# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Sugar_tr PF00083.19 EDN02138.1 - 3.3e-73 246.7 15.9 5.5e-73 246.0 11.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN02138.1 - 6.7e-13 48.0 27.5 1.6e-12 46.8 19.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Oxysterol_BP PF01237.13 EDN02139.1 - 3.7e-73 246.0 3.0 8.4e-61 205.4 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Kinesin-relat_1 PF12711.2 EDN02139.1 - 0.0062 16.9 0.2 0.016 15.6 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor RTA1 PF04479.8 EDN02140.1 - 1.3e-30 106.6 15.0 1.8e-30 106.1 10.4 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF788 PF05620.6 EDN02140.1 - 0.0034 17.2 0.0 0.0034 17.2 0.0 3.4 4 2 1 5 5 5 1 Protein of unknown function (DUF788) CUE PF02845.11 EDN02141.1 - 9.5e-10 37.7 0.0 1.5e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF2477 PF10631.4 EDN02143.1 - 2.8 8.1 7.1 4.2 7.5 4.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2477) UCH PF00443.24 EDN02144.1 - 5.5e-41 140.4 0.3 3.8e-34 118.0 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDN02144.1 - 9.7e-14 51.4 4.3 2.5e-13 50.1 0.7 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase InaF-motif PF15018.1 EDN02144.1 - 0.44 10.0 1.1 0.87 9.0 0.8 1.5 1 0 0 1 1 1 0 TRP-interacting helix Methyltransf_23 PF13489.1 EDN02145.1 - 5.5e-13 48.9 0.0 8.3e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN02145.1 - 8.7e-05 22.1 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN02145.1 - 0.0011 19.3 0.0 0.0024 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN02145.1 - 0.0058 17.1 0.0 0.06 13.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN02145.1 - 0.0096 16.3 0.0 0.03 14.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain F_bP_aldolase PF01116.15 EDN02146.1 - 3.5e-70 236.3 0.0 4e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF221 PF02714.10 EDN02148.1 - 1e-96 323.6 24.4 1.6e-96 322.9 16.9 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EDN02148.1 - 3.1e-41 140.5 2.9 3.1e-41 140.5 2.0 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EDN02148.1 - 2.3e-14 53.6 0.0 7e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF996 PF06195.8 EDN02148.1 - 0.034 14.1 0.5 0.034 14.1 0.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF996) DUF1192 PF06698.6 EDN02148.1 - 0.16 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3445 PF11927.3 EDN02149.1 - 1e-92 310.0 0.1 1.3e-92 309.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3169 PF11368.3 EDN02149.1 - 0.1 11.7 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Homoserine_dh PF00742.14 EDN02150.1 - 9.5e-51 172.0 0.0 1.3e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EDN02150.1 - 7.3e-12 45.7 0.0 2.6e-11 43.9 0.0 2.0 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF1010 PF06231.6 EDN02150.1 - 0.37 10.8 10.7 0.046 13.7 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1010) DUF4078 PF13300.1 EDN02151.1 - 6.6e-32 109.4 9.9 2.7e-31 107.5 6.8 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4078) HrpA_pilin PF09589.5 EDN02151.1 - 0.53 10.7 5.3 1.9 8.9 3.7 2.2 1 1 0 1 1 1 0 HrpA pilus formation protein ATG11 PF10377.4 EDN02152.1 - 1.9e-42 144.2 0.0 9.1e-42 142.0 0.0 2.3 1 0 0 1 1 1 1 Autophagy-related protein 11 APG17 PF04108.7 EDN02152.1 - 0.00018 20.4 2.0 0.00018 20.4 1.4 5.3 3 2 1 4 4 4 2 Autophagy protein Apg17 M_domain PF12938.2 EDN02152.1 - 0.02 14.7 2.7 1.1 9.0 0.1 2.9 2 0 0 2 2 2 0 M domain of GW182 ApoO PF09769.4 EDN02152.1 - 0.78 9.4 10.3 2.6 7.7 0.6 4.0 2 2 2 4 4 4 0 Apolipoprotein O RPW8 PF05659.6 EDN02152.1 - 0.94 9.0 10.8 3.3 7.2 0.1 4.6 4 1 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 CENP-H PF05837.7 EDN02153.1 - 4e-20 71.9 8.2 7.6e-19 67.8 0.5 2.1 1 1 1 2 2 2 2 Centromere protein H (CENP-H) YL1 PF05764.8 EDN02153.1 - 0.018 14.6 5.3 0.024 14.2 3.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein HMG_box PF00505.14 EDN02154.1 - 2.2e-24 85.5 1.5 2.2e-24 85.5 1.0 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDN02154.1 - 8.5e-19 67.7 2.0 8.5e-19 67.7 1.4 1.5 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 EDN02154.1 - 0.00088 19.0 0.8 0.00088 19.0 0.6 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 EDN02154.1 - 0.022 14.9 1.3 0.052 13.7 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) DUF1517 PF07466.6 EDN02158.1 - 0.047 12.6 0.3 0.076 11.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) SKG6 PF08693.5 EDN02158.1 - 0.053 12.8 0.2 0.053 12.8 0.1 2.1 3 0 0 3 3 3 0 Transmembrane alpha-helix domain Granulin PF00396.13 EDN02158.1 - 0.98 9.5 17.9 3.7 7.7 3.8 2.4 2 0 0 2 2 2 0 Granulin GMC_oxred_N PF00732.14 EDN02159.1 - 2e-32 112.5 0.0 2.9e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EDN02159.1 - 1.2e-06 27.6 0.5 1.9e-06 27.0 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GMC_oxred_C PF05199.8 EDN02159.1 - 1.4e-05 25.4 0.9 0.21 11.8 0.0 3.2 3 1 0 3 3 3 2 GMC oxidoreductase DAO PF01266.19 EDN02159.1 - 7.1e-05 21.8 0.1 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN02159.1 - 0.00026 20.9 0.3 0.00061 19.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDN02159.1 - 0.00036 19.7 0.3 0.00063 18.9 0.2 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EDN02159.1 - 0.00048 19.0 0.9 0.00071 18.5 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EDN02159.1 - 0.0028 17.4 0.0 0.0058 16.4 0.0 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDN02159.1 - 0.004 17.0 0.1 0.0065 16.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EDN02159.1 - 0.0057 15.3 0.4 0.0086 14.7 0.3 1.2 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.9 EDN02159.1 - 0.0073 14.8 0.6 0.011 14.2 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein DnaJ PF00226.26 EDN02160.1 - 4.4e-09 35.9 1.9 9.2e-09 34.9 1.3 1.6 1 0 0 1 1 1 1 DnaJ domain LEA_4 PF02987.11 EDN02163.1 - 0.037 13.9 4.5 0.037 13.9 3.1 2.5 3 1 0 3 3 3 0 Late embryogenesis abundant protein YbjQ_1 PF01906.12 EDN02163.1 - 0.045 14.1 0.7 0.079 13.3 0.5 1.5 1 1 0 1 1 1 0 Putative heavy-metal-binding Pilt PF15453.1 EDN02163.1 - 0.27 10.8 3.2 0.31 10.6 2.2 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DUF883 PF05957.8 EDN02163.1 - 0.45 10.9 6.2 1.4 9.3 2.2 2.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) UvsW PF11637.3 EDN02163.1 - 0.5 10.0 3.9 1.1 8.9 0.1 2.4 1 1 1 2 2 2 0 ATP-dependant DNA helicase UvsW YtxH PF12732.2 EDN02163.1 - 2.2 8.6 6.0 13 6.2 4.1 2.0 1 1 0 1 1 1 0 YtxH-like protein NB-ARC PF00931.17 EDN02164.1 - 1.7e-13 50.0 0.0 2.8e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EDN02164.1 - 3.4e-06 27.1 0.0 1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PGAP1 PF07819.8 EDN02164.1 - 0.0002 21.0 0.0 0.00048 19.7 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.7 EDN02164.1 - 0.00033 20.3 0.0 0.0025 17.5 0.0 2.2 2 0 0 2 2 2 1 NACHT domain Abhydrolase_6 PF12697.2 EDN02164.1 - 0.001 19.0 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Arch_ATPase PF01637.13 EDN02164.1 - 0.0015 18.2 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EDN02164.1 - 0.0041 17.2 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.9 EDN02164.1 - 0.0064 15.8 0.1 0.018 14.3 0.1 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) KaiC PF06745.8 EDN02164.1 - 0.0093 15.1 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_17 PF13207.1 EDN02164.1 - 0.019 15.7 0.0 0.051 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EDN02164.1 - 0.02 14.3 0.0 0.064 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Sigma54_activat PF00158.21 EDN02164.1 - 0.037 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EDN02164.1 - 0.044 12.8 0.4 0.49 9.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AFG1_ATPase PF03969.11 EDN02164.1 - 0.049 12.4 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase ECH PF00378.15 EDN02165.1 - 9.9e-51 172.2 0.3 1.2e-50 171.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pox_P21 PF05313.7 EDN02165.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DDE_1 PF03184.14 EDN02167.1 - 6.9e-06 25.3 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN02167.1 - 0.0033 16.9 0.2 0.0058 16.1 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN02167.1 - 0.083 12.7 0.0 0.19 11.5 0.0 1.8 1 1 0 1 1 1 0 Tc5 transposase DNA-binding domain FluMu_gp41 PF10109.4 EDN02168.1 - 0.016 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 Mu-like prophage FluMu protein gp41 Med28 PF11594.3 EDN02169.1 - 0.092 12.9 2.9 2.3 8.4 0.3 2.3 1 1 1 2 2 2 0 Mediator complex subunit 28 DUF1786 PF08735.5 EDN02169.1 - 0.17 11.0 0.2 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) GatB_N PF02934.10 EDN02170.1 - 5.5e-42 143.5 0.0 4.8e-19 68.2 0.0 3.1 1 1 2 3 3 3 3 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EDN02170.1 - 2.9e-11 43.2 0.3 4.4e-11 42.7 0.2 1.3 1 0 0 1 1 1 1 GatB domain Arginase PF00491.16 EDN02171.1 - 3e-79 266.2 0.3 3.5e-79 266.0 0.2 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.18 EDN02172.1 - 0.0088 15.8 18.0 0.016 15.0 12.5 1.5 1 1 0 1 1 1 1 Membrane-associating domain 7TMR-DISM_7TM PF07695.6 EDN02172.1 - 0.075 12.6 19.4 0.016 14.9 9.0 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling Asp PF00026.18 EDN02173.1 - 5.2e-106 354.4 0.1 6.5e-106 354.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDN02173.1 - 3.4e-12 46.6 0.1 1.4e-11 44.6 0.0 2.0 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EDN02173.1 - 1.7e-05 25.2 0.1 0.25 11.8 0.0 3.4 3 2 1 4 4 4 2 Aspartyl protease TAXi_C PF14541.1 EDN02173.1 - 2.5e-05 23.8 0.0 0.00035 20.1 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal NIF PF03031.13 EDN02174.1 - 1.8e-26 92.7 0.3 4.7e-26 91.3 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EDN02174.1 - 1.1e-11 44.4 0.1 2.1e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EDN02174.1 - 7.5e-10 38.8 0.4 4e-09 36.5 0.0 2.4 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain McrBC PF10117.4 EDN02174.1 - 0.035 13.0 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component AAA PF00004.24 EDN02175.1 - 8e-45 152.2 0.4 1.9e-44 151.0 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDN02175.1 - 1.8e-08 34.2 0.1 6.3e-08 32.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDN02175.1 - 9.9e-08 32.0 0.0 2.1e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EDN02175.1 - 1.5e-06 28.3 0.8 0.00055 20.0 0.5 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EDN02175.1 - 2.7e-06 26.4 0.0 6.1e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EDN02175.1 - 4.4e-06 26.8 0.0 1.4e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EDN02175.1 - 0.0003 20.6 0.0 0.0018 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN02175.1 - 0.0005 20.8 0.0 0.0047 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDN02175.1 - 0.00058 18.9 0.0 0.0013 17.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EDN02175.1 - 0.00066 19.6 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EDN02175.1 - 0.00072 18.3 0.0 0.0013 17.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus NACHT PF05729.7 EDN02175.1 - 0.0011 18.6 0.6 0.056 13.0 0.0 2.7 2 1 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EDN02175.1 - 0.002 17.8 0.4 0.0049 16.5 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain UPF0079 PF02367.12 EDN02175.1 - 0.002 17.7 0.0 0.016 14.8 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EDN02175.1 - 0.0031 17.6 0.0 0.0068 16.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EDN02175.1 - 0.0043 16.1 0.1 0.013 14.5 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 EDN02175.1 - 0.0063 15.9 0.1 0.024 14.0 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.1 EDN02175.1 - 0.0081 15.7 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EDN02175.1 - 0.0084 15.2 0.1 0.019 14.1 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EDN02175.1 - 0.0091 15.7 0.0 0.026 14.2 0.0 1.8 1 0 0 1 1 1 1 NTPase AAA_33 PF13671.1 EDN02175.1 - 0.0097 15.7 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EDN02175.1 - 0.01 15.4 0.1 0.034 13.7 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EDN02175.1 - 0.013 15.0 0.0 0.037 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EDN02175.1 - 0.015 15.5 0.0 0.054 13.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 EDN02175.1 - 0.016 14.7 0.2 0.041 13.4 0.2 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EDN02175.1 - 0.017 14.7 0.9 0.14 11.8 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase Bac_DnaA PF00308.13 EDN02175.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.1 EDN02175.1 - 0.023 14.0 2.6 0.11 11.9 0.1 2.4 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.1 EDN02175.1 - 0.026 14.8 0.4 0.84 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EDN02175.1 - 0.039 13.0 1.1 0.5 9.4 0.0 2.5 3 0 0 3 3 3 0 KaiC DivIVA PF05103.8 EDN02175.1 - 0.041 13.9 0.4 0.12 12.4 0.1 1.8 2 0 0 2 2 1 0 DivIVA protein Sigma54_activat PF00158.21 EDN02175.1 - 0.079 12.4 0.1 2 7.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EDN02175.1 - 0.13 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PfkB PF00294.19 EDN02176.1 - 1.7e-17 63.5 0.0 5.9e-17 61.7 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase ARID PF01388.16 EDN02178.1 - 2.7e-13 49.5 0.1 5.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Img2 PF05046.9 EDN02179.1 - 1.2e-28 99.1 0.0 2.4e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) eIF3_N PF09440.5 EDN02180.1 - 1.2e-54 184.0 4.2 2.9e-54 182.8 2.9 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EDN02180.1 - 1.3e-13 51.1 0.4 7.7e-13 48.6 0.0 2.5 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EDN02180.1 - 0.01 15.5 0.0 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 SAP PF02037.22 EDN02182.1 - 0.00033 20.0 1.8 0.00033 20.0 1.3 2.0 3 0 0 3 3 3 1 SAP domain DDE_1 PF03184.14 EDN02183.1 - 9.7e-29 100.0 0.0 1.9e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN02183.1 - 1.3e-05 24.8 0.0 5.5e-05 22.9 0.0 2.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN02183.1 - 0.0045 16.5 0.6 0.0045 16.5 0.4 2.2 2 0 0 2 2 2 1 helix-turn-helix, Psq domain TraG_N PF07916.6 EDN02183.1 - 0.64 8.3 3.7 0.92 7.8 2.6 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Borrelia_P83 PF05262.6 EDN02183.1 - 1 7.5 20.1 1.4 7.0 14.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein GBP_C PF02841.9 EDN02183.1 - 4.2 6.4 20.0 6.9 5.7 13.9 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF2229 PF09989.4 EDN02183.1 - 5.6 6.3 9.3 47 3.3 6.5 2.1 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) ArsA_ATPase PF02374.10 EDN02184.1 - 6.6e-114 380.0 0.0 7.6e-114 379.8 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EDN02184.1 - 1.5e-17 63.6 0.2 2.4e-17 62.9 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EDN02184.1 - 1.6e-08 34.6 0.0 1.7e-07 31.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EDN02184.1 - 1.9e-06 27.3 0.1 4.9e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EDN02184.1 - 3.3e-05 23.4 0.5 0.00079 18.9 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EDN02184.1 - 0.0032 16.8 0.2 0.013 14.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 EDN02184.1 - 0.0081 15.2 0.1 0.032 13.3 0.0 1.9 3 0 0 3 3 3 1 ATPase MipZ AAA_19 PF13245.1 EDN02184.1 - 0.0084 15.8 0.1 0.025 14.3 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain NB-ARC PF00931.17 EDN02184.1 - 0.0094 14.8 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain PhoH PF02562.11 EDN02184.1 - 0.02 14.1 0.1 0.048 12.8 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein YhjQ PF06564.7 EDN02184.1 - 0.024 13.9 0.0 0.061 12.6 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein IstB_IS21 PF01695.12 EDN02184.1 - 0.026 13.9 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AIP3 PF03915.8 EDN02184.1 - 0.093 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Transthyretin PF00576.16 EDN02185.1 - 4.3e-16 58.7 0.0 1.5e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 HIUase/Transthyretin family Mucin PF01456.12 EDN02185.1 - 0.015 15.0 14.3 0.021 14.5 9.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Aft1_HRA PF11786.3 EDN02186.1 - 8.2e-24 83.6 10.0 8.2e-24 83.6 6.9 2.3 2 0 0 2 2 2 1 Aft1 HRA domain Aft1_HRR PF11787.3 EDN02186.1 - 1.1e-23 84.0 3.6 1.1e-23 84.0 2.5 4.8 4 1 1 5 5 5 1 Aft1 HRR domain Aft1_OSA PF11785.3 EDN02186.1 - 1.7e-21 76.5 11.9 1.7e-21 76.5 8.3 3.8 4 0 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 EDN02186.1 - 8e-13 48.1 5.6 1.4e-12 47.3 3.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EDN02186.1 - 4.4e-07 29.6 5.6 4.4e-07 29.6 3.9 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EDN02186.1 - 0.0019 18.4 3.8 0.0019 18.4 2.6 3.0 2 1 1 3 3 3 1 bZIP Maf transcription factor Prp18 PF02840.10 EDN02186.1 - 0.043 13.6 0.4 0.12 12.1 0.2 1.8 1 1 0 1 1 1 0 Prp18 domain Spc97_Spc98 PF04130.8 EDN02187.1 - 5.5e-107 358.3 0.0 7.7e-107 357.8 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family FSA_C PF10479.4 EDN02187.1 - 0.087 10.8 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF2373 PF10180.4 EDN02188.1 - 1.6e-21 75.5 0.1 3.5e-21 74.5 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.21 EDN02189.1 - 1.2e-44 151.9 0.0 1.4e-40 138.6 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EDN02189.1 - 3.2e-12 45.5 0.3 6.2e-12 44.6 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribosomal_L27e PF01777.13 EDN02191.1 - 4.6e-38 129.2 4.0 5.9e-38 128.8 2.7 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EDN02191.1 - 0.00046 19.7 0.9 0.0015 18.1 0.1 2.3 2 0 0 2 2 2 1 KOW motif LPP PF04728.8 EDN02192.1 - 0.0015 18.3 10.1 0.1 12.4 0.3 4.9 3 0 0 3 3 3 2 Lipoprotein leucine-zipper HALZ PF02183.13 EDN02192.1 - 8.1 6.2 16.1 0.32 10.7 1.8 5.5 7 0 0 7 7 7 0 Homeobox associated leucine zipper TRAM_LAG1_CLN8 PF03798.11 EDN02193.1 - 5.6e-48 163.1 18.6 8.2e-48 162.5 12.9 1.2 1 0 0 1 1 1 1 TLC domain NfeD PF01957.13 EDN02193.1 - 0.069 13.2 0.1 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding PHD PF00628.24 EDN02194.1 - 6.8e-10 38.4 10.0 1.2e-09 37.6 6.9 1.4 1 0 0 1 1 1 1 PHD-finger FYVE_2 PF02318.11 EDN02194.1 - 0.1 12.5 3.4 0.19 11.6 2.3 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger C1_1 PF00130.17 EDN02194.1 - 0.11 12.2 7.3 0.044 13.5 2.5 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EDN02194.1 - 0.26 11.0 9.0 0.032 13.9 2.6 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EDN02194.1 - 1.2 8.4 9.5 0.19 11.0 3.0 2.3 2 1 0 2 2 2 0 PHD-finger zf-B_box PF00643.19 EDN02194.1 - 1.9 8.4 9.2 7.6 6.5 0.1 2.7 2 0 0 2 2 2 0 B-box zinc finger HypA PF01155.14 EDN02194.1 - 2.3 7.9 7.3 8.8 6.0 0.2 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Na_H_Exchanger PF00999.16 EDN02195.1 - 6.9e-33 113.7 33.5 5.5e-28 97.5 16.5 3.0 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family Tim54 PF11711.3 EDN02195.1 - 0.081 11.5 1.0 0.21 10.1 0.8 1.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CoA_transf_3 PF02515.12 EDN02196.1 - 2.7e-57 193.1 0.0 3.7e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Lum_binding PF00677.12 EDN02197.1 - 4.6e-40 135.4 0.3 1.4e-22 79.3 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain Brix PF04427.13 EDN02198.1 - 1.1e-48 165.4 0.8 1.4e-48 165.0 0.6 1.1 1 0 0 1 1 1 1 Brix domain CAF-1_p150 PF11600.3 EDN02198.1 - 0.075 12.4 20.6 0.18 11.1 14.3 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FoP_duplication PF13865.1 EDN02198.1 - 0.16 12.4 15.1 0.054 13.9 7.9 2.2 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 DEAD PF00270.24 EDN02199.1 - 3.2e-46 156.8 0.0 5.2e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN02199.1 - 3e-26 91.1 0.0 7.5e-26 89.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN02199.1 - 0.0014 18.5 0.0 0.0045 16.8 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EDN02199.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain PGM_PMM_I PF02878.11 EDN02200.1 - 2.6e-16 59.3 0.0 1.3e-08 34.3 0.0 2.9 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EDN02200.1 - 1.3e-15 57.5 0.1 6.1e-15 55.4 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EDN02200.1 - 9.4e-11 41.5 1.2 3.6e-10 39.6 0.3 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EDN02200.1 - 0.0024 17.9 0.0 0.0051 16.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Per1 PF04080.8 EDN02201.1 - 4.6e-107 357.4 8.4 5.7e-107 357.1 5.8 1.1 1 0 0 1 1 1 1 Per1-like PrmA PF06325.8 EDN02202.1 - 2.2e-11 43.4 0.0 3.8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EDN02202.1 - 4.6e-11 42.5 0.0 7.4e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN02202.1 - 4.8e-09 36.2 0.0 1.3e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN02202.1 - 6.4e-09 36.3 0.0 1.1e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EDN02202.1 - 1.6e-07 30.5 0.0 3e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 EDN02202.1 - 2e-07 31.4 0.0 3.7e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN02202.1 - 4e-06 27.1 0.0 1.2e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN02202.1 - 4.5e-06 26.4 0.0 7.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EDN02202.1 - 5.8e-06 25.2 0.1 9.5e-06 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 EDN02202.1 - 4.7e-05 22.8 0.0 8.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EDN02202.1 - 5.6e-05 22.3 0.0 7.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EDN02202.1 - 0.0013 18.7 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 EDN02202.1 - 0.0027 18.1 0.0 0.0052 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EDN02202.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.1 EDN02202.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EDN02202.1 - 0.044 13.3 0.1 0.069 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MaoC_dehydratas PF01575.14 EDN02203.1 - 7.8e-19 67.2 0.0 1.4e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EDN02203.1 - 1.2e-07 31.6 0.0 7.3e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase SIC PF03482.8 EDN02203.1 - 0.04 13.5 0.8 0.056 13.0 0.5 1.1 1 0 0 1 1 1 0 sic protein TauD PF02668.11 EDN02204.1 - 6e-27 94.9 0.0 9e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AAA PF00004.24 EDN02205.1 - 2.3e-41 141.1 0.2 8.1e-41 139.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDN02205.1 - 1.2e-07 31.5 2.2 0.00024 20.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EDN02205.1 - 0.0001 21.4 0.0 0.00037 19.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EDN02205.1 - 0.0002 21.4 0.1 0.011 15.7 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EDN02205.1 - 0.00037 20.6 0.2 0.021 14.9 0.0 2.9 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 EDN02205.1 - 0.00048 19.1 1.3 0.012 14.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 EDN02205.1 - 0.0012 18.7 2.0 0.0039 17.1 0.0 2.8 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EDN02205.1 - 0.0021 17.3 1.2 0.033 13.4 0.1 2.5 3 0 0 3 3 3 1 PhoH-like protein Mg_chelatase PF01078.16 EDN02205.1 - 0.0065 15.6 0.1 0.019 14.0 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EDN02205.1 - 0.0096 15.7 0.0 0.028 14.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN02205.1 - 0.014 15.0 0.3 0.036 13.8 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EDN02205.1 - 0.02 14.3 0.1 0.039 13.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 EDN02205.1 - 0.036 13.6 0.1 0.14 11.7 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDN02205.1 - 0.047 13.0 1.1 0.44 9.9 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EDN02205.1 - 0.065 14.0 0.1 0.065 14.0 0.1 3.0 2 2 0 2 2 1 0 AAA domain AAA_11 PF13086.1 EDN02205.1 - 0.14 11.7 4.4 0.38 10.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain F-box-like PF12937.2 EDN02206.1 - 0.00054 19.6 1.4 0.0019 17.8 0.4 2.5 2 1 0 2 2 2 1 F-box-like Pkinase PF00069.20 EDN02207.1 - 1.1e-72 244.2 0.0 2.1e-72 243.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02207.1 - 5.8e-32 110.7 0.0 8.8e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EDN02207.1 - 4.4e-12 46.3 2.3 4.4e-12 46.3 0.0 2.3 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EDN02207.1 - 1e-09 37.8 0.1 2.1e-09 36.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 EDN02207.1 - 0.0016 18.2 0.1 0.069 13.0 0.1 2.6 2 0 0 2 2 2 1 C2 domain APH PF01636.18 EDN02207.1 - 0.0027 17.4 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EDN02207.1 - 0.034 13.4 0.0 0.088 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EDN02207.1 - 0.097 11.7 0.1 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4246 PF14033.1 EDN02208.1 - 1.9e-181 604.0 2.5 1.5e-122 409.7 0.8 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EDN02208.1 - 0.00085 19.5 0.0 0.0023 18.1 0.0 1.7 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 EDN02208.1 - 0.098 13.1 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily CRC_subunit PF08624.5 EDN02209.1 - 1.9e-57 193.0 0.0 3e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit TrkH PF02386.11 EDN02210.1 - 1.9e-45 154.9 1.2 6.5e-41 140.0 0.2 2.9 2 1 0 2 2 2 2 Cation transport protein Cyclin PF08613.6 EDN02211.1 - 2.5e-14 53.9 0.0 3.3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EDN02211.1 - 0.0072 15.8 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Atrophin-1 PF03154.10 EDN02212.1 - 0.0065 14.6 7.7 0.0065 14.6 5.4 1.6 2 0 0 2 2 2 1 Atrophin-1 family DUF1777 PF08648.7 EDN02212.1 - 3.5 7.3 15.5 0.04 13.6 5.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1777) Dor1 PF04124.7 EDN02213.1 - 3.4e-55 186.8 2.7 2.6e-49 167.5 1.8 2.5 1 1 1 2 2 2 2 Dor1-like family Vps51 PF08700.6 EDN02213.1 - 0.004 16.9 0.2 0.011 15.4 0.1 1.8 1 0 0 1 1 1 1 Vps51/Vps67 EAF PF09816.4 EDN02214.1 - 4.6e-25 87.7 0.2 4.6e-25 87.7 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor Cyclin_N PF00134.18 EDN02214.1 - 7.8e-15 54.5 0.2 7.8e-15 54.5 0.1 2.4 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDN02214.1 - 4.3e-07 29.8 0.4 2e-05 24.4 0.0 2.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 EDN02214.1 - 0.0059 16.3 5.0 0.75 9.6 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Methyltransf_23 PF13489.1 EDN02216.1 - 7.5e-27 94.0 0.0 1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN02216.1 - 5.4e-06 26.8 0.0 0.16 12.4 0.0 2.9 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EDN02216.1 - 8.8e-06 26.0 0.1 7.9e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN02216.1 - 6.1e-05 22.6 0.0 0.018 14.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EDN02216.1 - 6.4e-05 23.5 0.0 0.00016 22.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN02216.1 - 0.0001 22.7 0.0 0.017 15.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN02216.1 - 0.0048 16.0 0.0 0.14 11.2 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Pex14_N PF04695.8 EDN02216.1 - 0.099 12.6 5.9 1.3 9.1 0.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DAO PF01266.19 EDN02217.1 - 4.7e-52 177.0 0.9 5.9e-52 176.7 0.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDN02217.1 - 2.3e-08 34.1 0.3 0.0016 18.3 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN02217.1 - 1.9e-05 24.4 0.4 0.06 13.1 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 EDN02217.1 - 2.1e-05 23.5 0.1 0.0013 17.6 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EDN02217.1 - 0.00015 20.8 0.1 0.0086 15.0 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EDN02217.1 - 0.00022 20.0 0.1 0.084 11.4 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EDN02217.1 - 0.0007 19.5 1.1 0.0012 18.8 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EDN02217.1 - 0.002 18.5 0.0 0.0059 16.9 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDN02217.1 - 0.0038 17.3 0.1 4.6 7.2 0.1 3.0 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDN02217.1 - 0.013 14.3 0.5 1.2 7.8 0.0 2.5 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 EDN02217.1 - 0.029 13.4 0.0 0.31 10.0 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.13 EDN02217.1 - 0.034 14.1 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain TBP PF00352.16 EDN02218.1 - 9.7e-70 229.9 0.3 1e-34 117.7 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EDN02218.1 - 0.00011 22.1 0.0 0.43 10.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) ETF_QO PF05187.8 EDN02221.1 - 3.2e-46 155.8 0.0 5e-46 155.2 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EDN02221.1 - 1.9e-09 36.8 0.0 0.00017 20.6 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDN02221.1 - 9.4e-08 31.3 0.2 0.0024 16.7 0.5 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EDN02221.1 - 1e-05 25.4 0.0 2.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EDN02221.1 - 2.9e-05 23.3 0.0 5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDN02221.1 - 0.00011 22.2 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDN02221.1 - 0.00035 19.1 0.6 0.00055 18.5 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EDN02221.1 - 0.00084 19.4 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN02221.1 - 0.0016 17.5 0.0 0.0051 15.9 0.1 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EDN02221.1 - 0.0028 16.7 0.1 0.0046 16.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EDN02221.1 - 0.0034 17.7 0.1 4.7 7.7 0.3 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EDN02221.1 - 0.0052 15.4 0.1 0.076 11.6 0.1 2.2 1 1 1 2 2 2 1 Tryptophan halogenase Fer4_7 PF12838.2 EDN02221.1 - 0.0062 16.8 0.7 0.025 14.9 0.5 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain NAD_binding_9 PF13454.1 EDN02221.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EDN02221.1 - 0.031 13.2 0.3 0.049 12.5 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EDN02221.1 - 0.12 11.1 0.2 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A RRM_1 PF00076.17 EDN02222.1 - 1e-20 73.1 0.0 5.5e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN02222.1 - 4.4e-13 48.9 0.0 8.3e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN02222.1 - 5.2e-11 42.2 0.0 0.00028 20.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EDN02223.1 - 3.8e-63 213.0 0.0 5.1e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02223.1 - 2.3e-27 95.6 0.0 3.5e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FolB PF02152.13 EDN02223.1 - 2.6e-15 56.5 0.0 6e-13 48.9 0.1 2.6 2 0 0 2 2 2 1 Dihydroneopterin aldolase Kinase-like PF14531.1 EDN02223.1 - 0.031 13.2 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EDN02223.1 - 0.088 12.5 1.4 3.1 7.4 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ndc80_HEC PF03801.8 EDN02225.1 - 1.9e-64 215.9 0.2 5.7e-64 214.3 0.1 1.9 1 0 0 1 1 1 1 HEC/Ndc80p family IncA PF04156.9 EDN02225.1 - 0.0012 18.4 15.3 0.0012 18.4 10.6 3.8 2 2 2 4 4 4 1 IncA protein TPR_MLP1_2 PF07926.7 EDN02225.1 - 0.004 16.8 9.6 0.004 16.8 6.6 3.7 2 2 1 3 3 3 2 TPR/MLP1/MLP2-like protein GAS PF13851.1 EDN02225.1 - 0.0053 15.9 16.6 0.0053 15.9 11.5 3.0 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding Cast PF10174.4 EDN02225.1 - 0.01 13.9 40.1 0.16 9.9 10.8 2.1 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Filament PF00038.16 EDN02225.1 - 0.3 10.5 42.9 1.8 7.9 14.1 2.7 2 1 0 2 2 2 0 Intermediate filament protein Pex14_N PF04695.8 EDN02226.1 - 4.7e-38 130.3 11.6 5.9e-38 129.9 0.0 2.7 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 EDN02226.1 - 0.037 13.6 0.1 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 IncA protein DUF3584 PF12128.3 EDN02226.1 - 0.072 10.4 1.6 0.1 9.9 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-C4H2 PF10146.4 EDN02226.1 - 0.49 10.3 4.5 0.12 12.3 0.9 1.7 2 1 0 2 2 2 0 Zinc finger-containing protein DUF1664 PF07889.7 EDN02226.1 - 0.87 9.3 2.8 2.8 7.7 1.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4164 PF13747.1 EDN02226.1 - 0.97 9.6 9.2 0.55 10.3 2.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) FlgN PF05130.7 EDN02226.1 - 0.97 9.6 6.0 0.13 12.5 1.2 1.7 2 0 0 2 2 2 0 FlgN protein ABC_tran PF00005.22 EDN02228.1 - 1.1e-36 126.0 0.0 3.5e-36 124.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EDN02228.1 - 1.7e-15 57.1 8.8 1.7e-15 57.1 6.1 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EDN02228.1 - 0.001 18.3 0.0 0.0035 16.5 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EDN02228.1 - 0.0024 17.0 0.0 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EDN02228.1 - 0.0099 14.9 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_21 PF13304.1 EDN02228.1 - 0.012 15.5 0.0 0.84 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EDN02228.1 - 0.048 13.1 0.7 0.16 11.5 0.0 2.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EDN02228.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 EDN02228.1 - 0.067 12.0 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SbcCD_C PF13558.1 EDN02228.1 - 2.9 7.8 6.0 0.6 10.0 0.1 2.9 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Seipin PF06775.9 EDN02229.1 - 7.9e-66 221.3 0.3 1.2e-65 220.8 0.2 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) TTL PF03133.10 EDN02229.1 - 1e-51 175.6 0.0 2.3e-51 174.4 0.0 1.5 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EDN02229.1 - 1.2e-32 112.8 0.0 2.4e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 EDN02229.1 - 0.0011 17.7 0.0 0.0062 15.3 0.0 2.0 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 EDN02229.1 - 0.0048 16.6 0.0 0.96 9.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EDN02229.1 - 0.19 11.1 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Not1 PF04054.10 EDN02230.1 - 9.8e-143 475.5 2.3 1.6e-142 474.8 0.4 2.4 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EDN02230.1 - 2.9e-51 173.0 1.0 8e-51 171.5 0.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) FCH PF00611.18 EDN02231.1 - 9e-21 73.8 0.2 5.1e-20 71.4 0.0 2.5 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Tic20 PF09685.5 EDN02232.1 - 2.1e-07 30.9 1.4 2.7e-07 30.5 1.0 1.2 1 0 0 1 1 1 1 Tic20-like protein DASH_Duo1 PF08651.5 EDN02233.1 - 5.8e-30 102.6 1.3 1e-29 101.9 0.9 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF745 PF05335.8 EDN02233.1 - 0.0019 17.7 4.6 0.0033 16.9 3.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF745) zf-primase PF09329.6 EDN02235.1 - 9.4e-20 69.9 0.4 2e-19 68.8 0.3 1.6 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.5 EDN02236.1 - 2e-63 214.3 2.9 2.6e-63 214.0 2.0 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Menin PF05053.8 EDN02236.1 - 0.0066 14.6 0.8 0.011 13.9 0.5 1.3 1 0 0 1 1 1 1 Menin DUF1682 PF07946.9 EDN02236.1 - 0.024 13.4 4.6 0.037 12.8 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PVL_ORF50 PF07768.6 EDN02236.1 - 8.3 6.4 13.3 1 9.3 5.1 2.4 3 0 0 3 3 3 0 PVL ORF-50-like family GalKase_gal_bdg PF10509.4 EDN02237.1 - 6.4e-19 66.9 0.0 1.3e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EDN02237.1 - 5.8e-14 52.0 0.0 1.3e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EDN02237.1 - 7.3e-13 48.3 1.1 1.9e-12 47.0 0.8 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain HTH_3 PF01381.17 EDN02237.1 - 0.036 13.9 0.1 1.2 9.0 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix Methyltransf_23 PF13489.1 EDN02238.1 - 2.4e-23 82.6 0.0 5.6e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN02238.1 - 1e-10 42.1 0.1 7e-10 39.4 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN02238.1 - 1.5e-08 34.3 0.0 6.5e-08 32.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN02238.1 - 3.2e-08 33.9 0.0 1.7e-07 31.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN02238.1 - 5.5e-07 29.9 0.0 9.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN02238.1 - 4.3e-05 23.8 0.0 7.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EDN02238.1 - 0.0035 16.4 0.0 0.0099 14.9 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EDN02238.1 - 0.0039 16.5 0.0 0.013 14.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EDN02238.1 - 0.035 13.2 0.0 0.21 10.6 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EDN02238.1 - 0.094 12.2 0.1 1.4 8.3 0.1 2.1 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EDN02238.1 - 0.11 11.5 0.1 2.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Acyl_transf_1 PF00698.16 EDN02239.1 - 3.1e-48 164.7 0.0 7.3e-48 163.5 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EDN02239.1 - 6.8e-48 163.3 0.0 1.1e-47 162.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 EDN02239.1 - 9.4e-42 143.2 0.1 9.1e-30 103.9 0.0 2.5 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EDN02239.1 - 6.4e-37 126.0 0.0 6.4e-37 126.0 0.0 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EDN02239.1 - 4.3e-28 98.2 4.9 5.5e-25 88.0 0.1 2.8 1 1 1 2 2 2 2 KR domain adh_short PF00106.20 EDN02239.1 - 1.5e-19 70.5 3.7 6.2e-17 62.0 0.1 2.8 1 1 1 2 2 2 2 short chain dehydrogenase ADH_zinc_N PF00107.21 EDN02239.1 - 1.8e-19 69.6 0.0 6.9e-19 67.6 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EDN02239.1 - 4.9e-19 68.6 0.0 1.8e-18 66.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN02239.1 - 1.8e-15 56.9 0.0 4.4e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN02239.1 - 4.5e-14 52.3 0.0 1.4e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN02239.1 - 5.9e-10 39.5 0.0 1.9e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN02239.1 - 1.5e-08 35.2 0.0 6.1e-08 33.2 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EDN02239.1 - 9.2e-08 33.0 0.0 1.4e-06 29.1 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN02239.1 - 1.7e-07 30.9 0.5 4.3e-07 29.6 0.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.1 EDN02239.1 - 6.5e-05 23.2 0.0 0.00021 21.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN02239.1 - 0.00061 18.9 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EDN02239.1 - 0.0032 17.6 0.2 0.011 15.9 0.1 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site DUF938 PF06080.7 EDN02239.1 - 0.0065 16.0 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 EDN02239.1 - 0.0075 16.2 0.0 0.026 14.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 EDN02239.1 - 0.02 14.3 0.0 0.084 12.2 0.0 1.9 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TPP_enzyme_N PF02776.13 EDN02240.1 - 5.2e-51 172.5 0.1 1.1e-50 171.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EDN02240.1 - 5.7e-49 165.6 0.4 8e-47 158.6 0.0 3.0 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDN02240.1 - 3.4e-38 130.4 0.3 8.6e-38 129.1 0.1 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EDN02240.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CO_dh PF02552.11 EDN02240.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit RINGv PF12906.2 EDN02241.1 - 2.5e-05 24.2 6.9 4.2e-05 23.4 4.8 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EDN02241.1 - 0.00012 22.0 3.3 0.00022 21.1 2.3 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EDN02241.1 - 0.0026 17.5 5.8 0.0041 16.9 4.0 1.3 1 0 0 1 1 1 1 Ring finger domain PsbK PF02533.10 EDN02241.1 - 8.5 6.4 6.9 2.3 8.2 0.3 2.7 3 0 0 3 3 3 0 Photosystem II 4 kDa reaction centre component MRP-L28 PF09812.4 EDN02242.1 - 7.3e-07 29.1 0.0 9.3e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Ras PF00071.17 EDN02243.1 - 1.4e-46 157.8 0.0 1.6e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN02243.1 - 1.6e-16 60.8 0.0 2.9e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN02243.1 - 5e-07 29.1 0.0 6.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDN02243.1 - 0.0021 17.3 0.0 0.0034 16.6 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EDN02243.1 - 0.011 15.2 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EDN02243.1 - 0.015 14.4 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region NST1 PF13945.1 EDN02244.1 - 2.1e-81 272.5 6.2 2.1e-81 272.5 4.3 2.6 2 1 0 2 2 2 1 Salt tolerance down-regulator Nucleoplasmin PF03066.10 EDN02244.1 - 0.11 12.0 16.0 0.33 10.4 0.8 2.5 2 0 0 2 2 2 0 Nucleoplasmin Vps35 PF03635.12 EDN02247.1 - 0 1027.7 1.4 0 1027.5 1.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 WD40 PF00400.27 EDN02248.1 - 0.01 15.6 9.8 4 7.4 0.0 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF1749 PF08538.5 EDN02249.1 - 2e-93 312.6 0.0 2.4e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.2 EDN02249.1 - 2.6e-06 27.2 0.0 5.5e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN02249.1 - 0.00016 21.5 0.0 0.00022 21.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EDN02249.1 - 0.011 15.3 0.0 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase PGAP1 PF07819.8 EDN02249.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein NRDE-2 PF08424.5 EDN02249.1 - 0.26 10.1 0.7 0.39 9.5 0.5 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Glycos_transf_2 PF00535.21 EDN02250.1 - 3.6e-33 114.6 0.0 4.4e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EDN02250.1 - 2.7e-13 50.2 0.0 4e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EDN02250.1 - 1e-07 31.3 0.0 1.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EDN02250.1 - 0.00039 19.7 0.0 0.00067 18.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 TPR_19 PF14559.1 EDN02251.1 - 7.3e-08 32.6 2.6 0.0014 18.9 0.1 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDN02251.1 - 0.0004 20.2 3.8 0.0043 16.9 0.6 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDN02251.1 - 0.00083 19.9 3.7 0.074 13.7 0.1 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDN02251.1 - 0.01 16.2 1.4 20 5.9 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDN02251.1 - 0.09 12.7 4.5 7 6.8 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDN02251.1 - 0.11 12.5 2.5 2.3 8.2 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EDN02251.1 - 0.12 12.0 2.1 0.58 9.8 0.1 2.9 2 1 1 3 3 3 0 TPR repeat SAC3_GANP PF03399.11 EDN02252.1 - 4.9e-06 26.2 0.2 1.2e-05 24.9 0.1 1.5 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EDN02252.1 - 0.038 13.7 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 HlyIII PF03006.15 EDN02253.1 - 7.6e-59 198.7 17.4 8.7e-59 198.6 12.1 1.0 1 0 0 1 1 1 1 Haemolysin-III related adh_short PF00106.20 EDN02254.1 - 1.2e-19 70.8 2.5 2.1e-13 50.5 0.0 2.5 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EDN02254.1 - 2.6e-16 60.1 0.7 3.7e-14 53.0 0.0 2.7 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN02254.1 - 1.2e-06 28.3 0.9 0.0008 19.1 0.0 2.2 1 1 1 2 2 2 2 KR domain AdoHcyase_NAD PF00670.16 EDN02254.1 - 0.02 14.7 0.5 0.045 13.5 0.4 1.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 EDN02254.1 - 0.086 12.4 0.2 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.20 EDN02255.1 - 3.2e-38 131.3 0.0 4.5e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02255.1 - 4.5e-20 71.8 0.0 6.2e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN02255.1 - 0.0023 16.9 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN02255.1 - 0.004 16.9 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EDN02255.1 - 0.022 13.8 0.0 0.031 13.3 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EDN02255.1 - 0.08 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.15 EDN02255.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrhK PF14145.1 EDN02256.1 - 2e-05 24.1 21.7 0.00073 19.1 0.5 5.0 2 2 2 4 4 4 3 YrhK-like protein Pkinase PF00069.20 EDN02257.1 - 1e-52 178.8 0.0 2.1e-52 177.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02257.1 - 5.9e-23 81.2 0.0 1.9e-22 79.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EDN02257.1 - 0.022 13.5 0.1 0.032 13.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TMA7 PF09072.5 EDN02258.1 - 1.7e-26 92.4 22.4 1.8e-26 92.3 15.5 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 LMP PF04778.7 EDN02259.1 - 0.071 12.8 1.7 0.072 12.8 0.1 1.7 2 0 0 2 2 2 0 LMP repeated region IncA PF04156.9 EDN02259.1 - 0.13 11.8 0.5 0.2 11.2 0.4 1.2 1 0 0 1 1 1 0 IncA protein Cyt-b5 PF00173.23 EDN02260.1 - 6e-15 54.8 0.0 8.4e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ish1 PF10281.4 EDN02261.1 - 3e-77 254.2 12.8 6.6e-14 51.6 0.0 7.4 7 0 0 7 7 7 6 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EDN02261.1 - 1e-06 28.1 0.5 0.66 9.5 0.0 4.8 5 0 0 5 5 5 3 HeH/LEM domain Slx4 PF09494.5 EDN02261.1 - 8.2e-06 25.4 0.6 8.5 6.2 0.0 4.8 5 0 0 5 5 5 2 Slx4 endonuclease SAP PF02037.22 EDN02261.1 - 0.00063 19.1 0.0 3.1 7.4 0.0 4.9 5 0 0 5 5 5 1 SAP domain APC2 PF08672.6 EDN02261.1 - 0.0062 16.7 3.2 28 5.0 0.0 5.1 6 0 0 6 6 6 0 Anaphase promoting complex (APC) subunit 2 ECM11 PF15463.1 EDN02261.1 - 0.0084 16.4 0.5 0.025 14.8 0.3 1.9 1 0 0 1 1 1 1 Extracellular mutant protein 11 Tir_receptor_M PF03549.9 EDN02261.1 - 0.032 14.3 0.0 2.6 8.2 0.0 3.3 3 0 0 3 3 3 0 Translocated intimin receptor (Tir) intimin-binding domain Kua-UEV1_localn PF10520.4 EDN02261.1 - 0.048 13.3 0.1 3.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain Rotamase_2 PF13145.1 EDN02261.1 - 1.3 9.6 5.3 1.1e+02 3.4 3.7 3.8 2 1 0 2 2 2 0 PPIC-type PPIASE domain PQ-loop PF04193.9 EDN02262.1 - 1.3e-12 47.0 2.3 1.3e-12 47.0 1.6 2.9 3 1 1 4 4 4 1 PQ loop repeat DUF1240 PF06836.7 EDN02262.1 - 0.54 10.5 4.8 0.077 13.2 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) DUF3611 PF12263.3 EDN02262.1 - 2.3 7.5 7.9 0.46 9.8 1.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3611) DUF3112 PF11309.3 EDN02262.1 - 2.5 7.8 10.8 6.3 6.5 7.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) DUF1628 PF07790.6 EDN02264.1 - 0.048 14.4 1.3 0.12 13.1 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) DUF3169 PF11368.3 EDN02264.1 - 0.17 11.0 1.2 0.27 10.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Gly-zipper_Omp PF13488.1 EDN02264.1 - 0.21 11.2 10.1 0.41 10.3 7.0 1.4 1 0 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.10 EDN02264.1 - 0.32 10.7 11.0 0.59 9.8 7.6 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 EDN02264.1 - 0.73 9.3 11.1 1.5 8.3 7.7 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 EDN02264.1 - 9.2 5.9 6.8 19 4.9 4.7 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain SAM_MT PF04445.8 EDN02265.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Surp PF01805.15 EDN02266.1 - 3.6e-18 64.9 0.0 6.3e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Surp module TEX19 PF15553.1 EDN02266.1 - 9.9 6.0 10.1 16 5.3 2.3 3.0 2 1 1 3 3 3 0 Testis-expressed protein 19 NTF2 PF02136.15 EDN02267.1 - 3e-15 56.6 0.0 4.8e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Polyoma_coat PF00718.15 EDN02267.1 - 0.042 12.7 0.0 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein Cg6151-P PF10233.4 EDN02268.1 - 3.6e-39 133.2 13.8 4.3e-39 132.9 9.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Cytochrom_B558a PF05038.8 EDN02268.1 - 2.8 7.5 5.9 1e+02 2.4 4.1 2.3 1 1 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit PRA1 PF03208.14 EDN02268.1 - 8 5.7 15.2 19 4.5 10.5 1.6 1 1 0 1 1 1 0 PRA1 family protein WD40 PF00400.27 EDN02269.1 - 1.2e-56 186.6 23.8 1.4e-11 43.7 0.1 10.4 11 0 0 11 11 10 7 WD domain, G-beta repeat NACHT PF05729.7 EDN02269.1 - 2.9e-12 46.5 0.1 7.5e-12 45.2 0.1 1.6 1 0 0 1 1 1 1 NACHT domain eIF2A PF08662.6 EDN02269.1 - 9.2e-11 41.8 0.0 0.18 11.4 0.0 5.2 1 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EDN02269.1 - 4.7e-07 29.3 0.3 21 4.9 0.0 6.3 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EDN02269.1 - 4.3e-06 26.0 0.7 2.4 7.2 0.0 4.7 3 2 2 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EDN02269.1 - 1.1e-05 23.7 1.0 0.39 8.8 0.0 4.5 3 1 1 4 4 4 1 Nucleoporin Nup120/160 AAA_16 PF13191.1 EDN02269.1 - 0.00015 21.7 0.1 0.00053 20.0 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EDN02269.1 - 0.0031 16.4 0.0 0.0066 15.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EDN02269.1 - 0.0034 17.5 0.3 0.012 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Cytochrom_D1 PF02239.11 EDN02269.1 - 0.0073 14.6 0.0 4.6 5.4 0.0 3.4 3 0 0 3 3 3 1 Cytochrome D1 heme domain APS_kinase PF01583.15 EDN02269.1 - 0.02 14.5 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_19 PF13245.1 EDN02269.1 - 0.022 14.4 0.0 0.072 12.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EDN02269.1 - 0.065 12.9 0.7 1.1 8.8 0.0 2.6 3 0 0 3 3 3 0 Archaeal ATPase RNA_helicase PF00910.17 EDN02269.1 - 0.068 13.3 0.0 0.28 11.3 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EDN02269.1 - 0.078 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EDN02269.1 - 0.11 13.3 0.3 0.67 10.7 0.2 2.4 1 1 0 1 1 1 0 AAA domain RVT_1 PF00078.22 EDN02272.1 - 1.1e-13 51.0 0.0 5.3e-12 45.5 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 EDN02272.1 - 0.092 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EDN02273.1 - 0.0018 18.1 5.0 0.0031 17.3 3.5 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF2353 PF09789.4 EDN02273.1 - 0.014 14.6 4.3 0.017 14.4 3.0 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Cytochrom_C550 PF14495.1 EDN02273.1 - 0.014 14.8 0.5 0.021 14.2 0.3 1.3 1 0 0 1 1 1 0 Cytochrome c-550 domain DUF2052 PF09747.4 EDN02273.1 - 0.033 14.1 5.0 0.036 13.9 3.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) zf-CCHC_2 PF13696.1 EDN02273.1 - 0.048 13.1 2.0 0.087 12.3 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Cep57_CLD_2 PF14197.1 EDN02273.1 - 2.5 8.1 7.8 0.16 11.9 1.8 1.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 RVT_1 PF00078.22 EDN02274.1 - 1.6e-07 30.9 0.0 1.9e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EDN02275.1 - 3.7e-30 104.8 0.0 1.1e-29 103.3 0.0 1.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN02275.1 - 4.6e-09 36.7 0.0 1.7e-08 34.8 0.0 2.0 1 1 0 1 1 1 1 RNase H DUF4398 PF14346.1 EDN02277.1 - 0.11 12.5 2.8 0.1 12.6 0.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) AAA PF00004.24 EDN02278.1 - 1.1e-14 54.7 0.0 1.6e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN02278.1 - 0.00095 19.1 0.0 0.027 14.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EDN02278.1 - 0.0021 17.4 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDN02278.1 - 0.02 13.9 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EDN02278.1 - 0.026 15.3 0.1 0.052 14.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EDN02278.1 - 0.033 14.3 0.2 0.71 10.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.9 EDN02278.1 - 0.11 12.1 0.1 0.54 9.9 0.0 2.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EDN02278.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EDN02278.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin IBR PF01485.16 EDN02280.1 - 8.3e-06 25.5 54.2 0.00036 20.3 7.2 5.3 5 1 0 5 5 5 3 IBR domain Nucleoplasmin PF03066.10 EDN02280.1 - 2.8 7.4 5.3 7.1 6.1 3.7 1.7 1 0 0 1 1 1 0 Nucleoplasmin Chalcone PF02431.10 EDN02281.1 - 3.5e-44 150.6 0.0 4.1e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Glutaredoxin PF00462.19 EDN02282.1 - 7.4e-09 35.4 0.0 9.6e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin VGCC_beta4Aa_N PF12052.3 EDN02283.1 - 0.4 10.5 6.6 0.95 9.3 4.6 1.7 1 1 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal BAG PF02179.11 EDN02285.1 - 2.1e-16 59.8 0.2 3.9e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 BAG domain LMBR1 PF04791.11 EDN02285.1 - 1e-08 34.2 0.0 1e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 LMBR1-like membrane protein NST1 PF13945.1 EDN02285.1 - 5.5 7.0 10.4 11 6.0 7.2 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Bactofilin PF04519.8 EDN02287.1 - 0.23 11.4 2.5 0.41 10.6 1.7 1.3 1 0 0 1 1 1 0 Polymer-forming cytoskeletal K-box PF01486.12 EDN02288.1 - 0.03 14.1 1.9 0.48 10.2 0.0 2.5 2 0 0 2 2 2 0 K-box region EamA PF00892.15 EDN02290.1 - 0.0004 20.4 3.4 0.00048 20.1 2.3 1.0 1 0 0 1 1 1 1 EamA-like transporter family MBOAT PF03062.14 EDN02291.1 - 8.1e-30 104.0 11.8 2.2e-29 102.5 8.2 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family TniB PF05621.6 EDN02292.1 - 0.041 12.6 0.0 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein Adaptin_N PF01602.15 EDN02293.1 - 6.3e-102 341.5 1.9 8.4e-102 341.1 1.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EDN02293.1 - 4.1e-10 39.9 0.0 8.3e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EDN02293.1 - 0.0034 17.6 4.9 2 8.7 0.1 4.0 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 EDN02293.1 - 0.014 15.2 3.0 0.049 13.4 0.3 3.1 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 EDN02293.1 - 0.017 14.7 0.1 0.048 13.2 0.1 1.8 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) HEAT PF02985.17 EDN02293.1 - 0.082 13.0 1.0 67 3.9 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat DUF563 PF04577.9 EDN02295.1 - 5.9e-35 121.0 0.0 9.4e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DnaJ PF00226.26 EDN02297.1 - 2.5e-22 78.3 0.9 5.2e-22 77.3 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L13 PF00572.13 EDN02300.1 - 2e-22 79.5 0.7 4.9e-11 42.7 0.0 2.5 1 1 1 2 2 2 2 Ribosomal protein L13 AMP-binding PF00501.23 EDN02301.1 - 2.5e-56 190.8 0.1 1.5e-39 135.5 0.0 2.0 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EDN02301.1 - 1.1e-07 32.6 0.0 2.5e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain F-box-like PF12937.2 EDN02302.1 - 1.1e-11 44.2 0.8 1.1e-11 44.2 0.6 2.5 3 0 0 3 3 3 1 F-box-like LRR_8 PF13855.1 EDN02302.1 - 3.8e-10 39.3 14.6 0.0059 16.3 0.2 5.7 3 2 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 EDN02302.1 - 9.3e-07 28.3 14.5 0.25 10.9 0.0 6.9 4 3 4 8 8 8 4 Leucine Rich repeats (2 copies) F-box PF00646.28 EDN02302.1 - 3e-06 26.7 4.7 4.3e-06 26.2 1.0 2.6 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.1 EDN02302.1 - 1.2e-05 24.8 23.8 4.5 7.6 0.1 10.7 13 0 0 13 13 13 1 Leucine Rich repeat LRR_1 PF00560.28 EDN02302.1 - 5e-05 22.7 21.2 30 5.1 0.0 10.1 10 1 0 10 10 10 0 Leucine Rich Repeat DUF1699 PF08004.6 EDN02302.1 - 0.031 13.7 0.3 0.6 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) STAS_2 PF13466.1 EDN02302.1 - 0.07 13.1 0.3 0.42 10.6 0.1 2.4 2 1 0 2 2 2 0 STAS domain Adeno_E4_34 PF04528.8 EDN02302.1 - 0.11 12.1 8.3 0.94 9.0 1.9 2.8 2 0 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region TPR_11 PF13414.1 EDN02303.1 - 0.00071 19.1 0.0 0.011 15.3 0.0 2.2 1 1 1 2 2 2 1 TPR repeat TPR_1 PF00515.23 EDN02303.1 - 0.00078 18.9 0.0 0.071 12.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDN02303.1 - 0.016 14.9 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDN02303.1 - 0.019 14.8 0.0 0.39 10.7 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDN02303.1 - 0.076 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDN02303.1 - 0.15 12.7 0.2 0.26 11.9 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Macoilin PF09726.4 EDN02303.1 - 9.6 4.3 8.6 14 3.7 5.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Peptidase_M28 PF04389.12 EDN02304.1 - 1.3e-15 57.5 0.0 2.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EDN02304.1 - 0.025 14.1 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Med10 PF09748.4 EDN02305.1 - 2.2e-31 108.3 0.0 2.6e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 EDN02305.1 - 0.094 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Pkinase PF00069.20 EDN02307.1 - 3e-38 131.4 0.0 4.5e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02307.1 - 1e-27 96.8 0.0 1.4e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN02307.1 - 0.00018 20.5 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDN02307.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF498 PF04430.9 EDN02307.1 - 0.14 11.7 0.1 0.32 10.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) MFS_1 PF07690.11 EDN02309.1 - 4.9e-22 78.1 11.4 5.5e-22 77.9 7.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EDN02309.1 - 0.00047 18.3 1.3 0.00067 17.8 0.9 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF4040 PF13244.1 EDN02309.1 - 0.072 13.0 1.7 5.8 6.9 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4040) ATG22 PF11700.3 EDN02309.1 - 0.9 7.9 12.1 2.7 6.3 0.1 2.1 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like HC2 PF07382.6 EDN02310.1 - 0.0095 15.8 32.2 0.015 15.1 22.3 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 DUF1614 PF07758.6 EDN02310.1 - 0.011 15.4 1.2 0.017 14.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1614) MIP-T3 PF10243.4 EDN02310.1 - 0.15 10.4 48.3 0.22 9.9 33.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Asp-B-Hydro_N PF05279.6 EDN02310.1 - 9.4 5.9 37.1 14 5.3 25.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4098 PF13345.1 EDN02311.1 - 2.5e-06 27.3 1.5 0.013 15.4 0.0 3.3 3 0 0 3 3 3 3 Domain of unknown function (DUF4098) TPR_1 PF00515.23 EDN02312.1 - 4.4e-30 102.0 9.9 2.7e-07 29.9 0.3 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EDN02312.1 - 2.7e-29 98.6 8.0 2.2e-06 27.1 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 EDN02312.1 - 6.1e-29 99.4 11.2 8.1e-19 67.0 0.8 4.8 5 0 0 5 5 5 3 TPR repeat DnaJ PF00226.26 EDN02312.1 - 4.4e-28 96.7 9.1 1.1e-27 95.5 1.2 3.6 4 0 0 4 4 3 1 DnaJ domain TPR_19 PF14559.1 EDN02312.1 - 8.7e-21 74.0 7.8 3e-06 27.4 0.3 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDN02312.1 - 2.2e-19 68.1 5.7 1.3e-05 25.3 0.1 6.5 4 2 3 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EDN02312.1 - 1.3e-18 67.1 6.1 6.3e-07 29.9 0.2 4.8 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDN02312.1 - 1.4e-15 55.7 5.3 0.0024 17.5 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 EDN02312.1 - 1.9e-14 52.2 10.1 0.0019 17.8 0.0 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EDN02312.1 - 1.5e-13 50.4 8.5 0.0059 16.5 0.0 4.7 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.1 EDN02312.1 - 2.3e-11 43.3 10.0 0.00066 19.9 0.0 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EDN02312.1 - 7.6e-11 42.0 3.9 9.5e-07 28.8 1.6 3.7 3 1 1 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EDN02312.1 - 1.1e-09 37.6 12.0 0.0065 16.5 0.3 6.5 8 0 0 8 8 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 EDN02312.1 - 2.2e-09 37.0 0.5 0.011 15.5 0.1 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 EDN02312.1 - 2.4e-06 26.8 3.5 0.0098 14.9 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 EDN02312.1 - 0.00014 21.9 0.4 2.7 8.6 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EDN02312.1 - 0.00017 21.3 5.9 1.5 8.8 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDN02312.1 - 0.001 18.8 3.5 1.3 8.9 0.0 3.8 1 1 2 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 EDN02312.1 - 0.0018 18.0 4.6 0.12 12.3 0.3 4.0 1 1 3 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 EDN02312.1 - 0.0069 16.1 0.3 5.1 7.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EDN02312.1 - 0.0087 16.2 2.1 0.2 11.8 1.1 2.7 1 1 0 1 1 1 1 Alkyl sulfatase dimerisation PPR PF01535.15 EDN02312.1 - 0.011 15.7 0.0 33 4.7 0.0 4.2 3 0 0 3 3 3 0 PPR repeat BTAD PF03704.12 EDN02312.1 - 0.029 14.6 1.3 1.1 9.5 0.2 3.4 2 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_20 PF14561.1 EDN02312.1 - 0.042 13.9 6.1 2.6 8.1 0.1 3.3 1 1 3 4 4 4 0 Tetratricopeptide repeat RPT PF13446.1 EDN02312.1 - 0.2 11.0 1.6 4.5 6.7 0.0 3.2 3 1 1 4 4 3 0 A repeated domain in UCH-protein DUF4451 PF14616.1 EDN02313.1 - 1.3e-33 115.4 0.3 2.5e-33 114.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Dynamin_N PF00350.18 EDN02314.1 - 1.6e-05 24.7 0.0 6.9e-05 22.7 0.0 2.1 1 0 0 1 1 1 1 Dynamin family PRP1_N PF06424.7 EDN02314.1 - 0.36 11.1 2.9 1.4 9.2 2.0 2.0 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Vps54 PF07928.7 EDN02316.1 - 2.4e-30 105.4 0.0 4.3e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Vps54-like protein Pkinase PF00069.20 EDN02317.1 - 4.1e-25 88.4 0.0 4.9e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02317.1 - 2.3e-16 59.6 0.0 2.9e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Acyltransferase PF01553.16 EDN02318.1 - 0.1 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Acyltransferase EHN PF06441.7 EDN02319.1 - 2.9e-35 120.5 0.3 3.7e-35 120.2 0.2 1.1 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EDN02319.1 - 0.0011 18.8 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN02319.1 - 0.057 12.9 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold tRNA_bind_2 PF13725.1 EDN02319.1 - 0.08 13.0 0.0 0.55 10.3 0.0 2.1 2 1 0 2 2 2 0 Possible tRNA binding domain Sec39 PF08314.6 EDN02320.1 - 3.9e-231 768.8 0.0 6.4e-141 470.6 0.0 2.0 1 1 1 2 2 2 2 Secretory pathway protein Sec39 Ndufs5 PF10200.4 EDN02321.1 - 9.7e-05 22.2 0.0 0.00012 22.0 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 EDN02321.1 - 0.0056 16.7 0.8 0.0099 15.9 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 EDN02321.1 - 0.026 14.5 0.2 0.036 14.0 0.2 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.7 EDN02321.1 - 0.13 12.1 1.3 0.22 11.3 0.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) DUF3535 PF12054.3 EDN02322.1 - 1.4e-156 521.6 0.1 5.6e-156 519.5 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) HEAT PF02985.17 EDN02322.1 - 1.6e-17 61.9 16.1 0.15 12.2 0.0 10.7 11 0 0 11 11 11 6 HEAT repeat HEAT_2 PF13646.1 EDN02322.1 - 3.5e-10 40.0 11.3 0.043 14.1 0.0 8.3 6 2 0 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EDN02322.1 - 5e-07 30.0 0.1 0.25 11.7 0.0 4.3 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EDN02322.1 - 0.00012 22.4 17.1 0.72 10.4 0.0 8.8 10 0 0 10 10 10 1 HEAT-like repeat CLASP_N PF12348.3 EDN02322.1 - 0.0025 17.1 1.3 0.18 11.1 0.0 3.8 3 1 2 5 5 5 1 CLASP N terminal SNF2_N PF00176.18 EDN02322.1 - 0.0036 16.1 0.1 0.0071 15.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cnd1 PF12717.2 EDN02322.1 - 0.0039 17.0 0.1 3.1 7.6 0.0 4.4 5 1 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 DUF1546 PF07571.8 EDN02322.1 - 0.0059 16.6 0.0 26 5.0 0.0 5.2 6 1 1 7 7 7 0 Protein of unknown function (DUF1546) Helicase_C PF00271.26 EDN02323.1 - 8.3e-16 57.6 0.0 2.3e-15 56.2 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain M16C_assoc PF08367.6 EDN02324.1 - 0.021 13.6 1.1 0.038 12.8 0.7 1.3 1 0 0 1 1 1 0 Peptidase M16C associated Erythro_esteras PF05139.9 EDN02325.1 - 2.7e-109 365.5 3.4 1.3e-106 356.7 0.1 2.0 1 1 1 2 2 2 2 Erythromycin esterase Scs3p PF10261.4 EDN02327.1 - 7.8e-10 38.2 0.9 1e-09 37.8 0.6 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM EBP PF05241.7 EDN02328.1 - 0.0025 16.8 5.9 0.0061 15.5 4.1 1.8 1 1 0 1 1 1 1 Emopamil binding protein Glyco_hydro_3 PF00933.16 EDN02329.1 - 5.4e-95 317.8 0.0 8.1e-95 317.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EDN02329.1 - 1.9e-57 194.4 0.1 6.7e-57 192.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain ClpB_D2-small PF10431.4 EDN02333.1 - 0.11 12.4 0.1 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein TBCA PF02970.11 EDN02334.1 - 0.073 13.1 5.5 0.13 12.3 1.0 2.0 1 1 1 2 2 2 0 Tubulin binding cofactor A DivIVA PF05103.8 EDN02334.1 - 0.24 11.4 4.5 0.27 11.3 3.1 1.2 1 0 0 1 1 1 0 DivIVA protein YebO PF13974.1 EDN02334.1 - 0.26 11.0 1.5 0.33 10.7 1.1 1.2 1 0 0 1 1 1 0 YebO-like protein DDRGK PF09756.4 EDN02334.1 - 2.8 7.3 10.3 3.3 7.0 7.2 1.0 1 0 0 1 1 1 0 DDRGK domain DDE_1 PF03184.14 EDN02335.1 - 0.00018 20.7 0.0 0.00027 20.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease UBN2 PF14223.1 EDN02337.1 - 0.013 15.2 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Imm3 PF14425.1 EDN02337.1 - 0.042 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Immunity protein Imm3 Fungal_trans PF04082.13 EDN02338.1 - 2.1e-22 79.2 0.0 2.9e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN02338.1 - 1.2e-09 37.9 11.7 2.2e-09 37.0 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EDN02339.1 - 0.95 7.6 32.4 1.2 7.3 22.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CIMR PF00878.13 EDN02340.1 - 0.0039 16.9 0.1 0.04 13.7 0.0 2.4 2 1 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat Herpes_LMP1 PF05297.6 EDN02340.1 - 3.8 6.3 5.3 4.9 5.9 3.7 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) ERG4_ERG24 PF01222.12 EDN02341.1 - 2.1e-12 46.3 0.0 2.4e-12 46.1 0.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family 60KD_IMP PF02096.15 EDN02341.1 - 0.12 12.0 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein A_deamin PF02137.13 EDN02342.1 - 2.8e-15 56.4 0.1 3.5e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain SF3b10 PF07189.6 EDN02343.1 - 6.3e-36 122.0 0.0 7e-36 121.8 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Stathmin PF00836.14 EDN02345.1 - 0.0045 16.6 6.3 0.0057 16.2 4.4 1.1 1 0 0 1 1 1 1 Stathmin family Cas_Csy4 PF09618.5 EDN02345.1 - 0.2 11.4 3.5 0.25 11.1 2.5 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) TMPIT PF07851.8 EDN02345.1 - 1.6 7.6 4.5 2.1 7.3 3.1 1.0 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.9 EDN02345.1 - 2 8.3 6.7 2.7 7.9 4.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4446 PF14584.1 EDN02345.1 - 5.7 6.7 6.4 7.1 6.4 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2058 PF09831.4 EDN02345.1 - 9.6 6.0 10.2 12 5.7 7.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) NT-C2 PF10358.4 EDN02346.1 - 2.9e-23 81.9 0.0 4.1e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SLS PF14611.1 EDN02347.1 - 3.9e-58 196.3 0.0 6.1e-58 195.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator MHYT PF03707.11 EDN02348.1 - 0.14 12.3 0.1 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat Myotub-related PF06602.9 EDN02349.1 - 2.6e-125 417.8 0.0 3.7e-125 417.3 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EDN02349.1 - 0.035 14.3 0.1 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 EDN02349.1 - 0.18 11.1 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase KH_2 PF07650.12 EDN02350.1 - 2.4e-12 46.2 0.1 3.9e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 KH domain Ribosomal_S3_C PF00189.15 EDN02350.1 - 1.1e-06 28.7 0.0 2.4e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain UN_NPL4 PF11543.3 EDN02350.1 - 0.053 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 B3_4 PF03483.12 EDN02351.1 - 4.2e-25 88.1 0.1 8.9e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EDN02351.1 - 2.1e-18 65.8 0.0 2.6e-15 55.9 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain HEAT PF02985.17 EDN02352.1 - 9.3e-43 140.4 14.9 0.0028 17.5 0.1 12.2 12 0 0 12 12 12 11 HEAT repeat HEAT_2 PF13646.1 EDN02352.1 - 6.8e-35 119.2 2.1 2.2e-09 37.4 0.0 7.2 3 2 4 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.2 EDN02352.1 - 2.2e-11 44.0 5.4 0.0007 19.9 0.1 6.9 5 2 3 8 8 8 4 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EDN02352.1 - 1.2e-09 38.3 11.3 0.036 14.5 0.0 8.4 6 3 4 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.15 EDN02352.1 - 3.7e-06 25.5 5.3 0.04 12.2 0.1 4.2 3 1 2 5 5 5 2 Adaptin N terminal region CLASP_N PF12348.3 EDN02352.1 - 0.0032 16.8 1.3 1.2 8.4 0.1 4.2 3 2 1 4 4 4 1 CLASP N terminal Arm PF00514.18 EDN02352.1 - 0.019 14.8 5.7 2.3 8.1 0.0 5.6 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 EDN02352.1 - 0.023 13.6 0.3 0.071 12.0 0.2 1.8 1 1 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.2 EDN02352.1 - 0.18 11.6 3.6 11 5.8 0.1 4.3 3 1 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 EDN02352.1 - 0.72 8.0 5.2 0.76 7.9 0.1 2.7 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit PI-PLC-X PF00388.14 EDN02353.1 - 7.6e-11 41.6 1.1 1.4e-10 40.7 0.8 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Glyco_transf_8 PF01501.15 EDN02353.1 - 0.00014 21.3 0.1 0.00022 20.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Prok-E2_E PF14462.1 EDN02353.1 - 0.51 9.9 2.0 1.9 8.1 0.5 2.2 2 0 0 2 2 2 0 Prokaryotic E2 family E Abhydrolase_6 PF12697.2 EDN02354.1 - 1.2e-23 84.2 3.3 1.9e-23 83.5 2.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN02354.1 - 6.7e-09 35.6 0.3 1.6e-08 34.3 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN02354.1 - 4e-08 33.0 0.1 1.5e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Arb2 PF09757.4 EDN02354.1 - 0.064 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Arb2 domain Glyco_transf_90 PF05686.7 EDN02355.1 - 6.1e-13 48.2 15.2 3e-10 39.3 7.7 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 CDO_I PF05995.7 EDN02356.1 - 1.4e-41 141.5 0.0 1.6e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EDN02356.1 - 0.00025 20.4 0.0 0.00031 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) TGS PF02824.16 EDN02357.1 - 1.1e-12 47.5 0.0 2.6e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EDN02357.1 - 3e-08 33.6 0.0 6.7e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDN02357.1 - 0.0096 15.7 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.22 EDN02357.1 - 0.025 14.0 0.1 1.9 7.8 0.0 3.1 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain RVT_2 PF07727.9 EDN02358.1 - 1.2e-58 197.9 0.0 8.1e-58 195.2 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN02358.1 - 4.1e-14 52.7 0.0 1.4e-13 50.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN02358.1 - 5.7e-08 32.2 0.0 2.3e-07 30.3 0.0 2.1 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 EDN02358.1 - 1.3 9.0 5.5 2.9 7.9 3.8 1.6 1 0 0 1 1 1 0 Zinc knuckle BTB PF00651.26 EDN02359.1 - 0.067 13.1 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain Ribosomal_L37 PF08561.5 EDN02361.1 - 2.5e-27 94.2 2.2 2.6e-26 90.9 1.5 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 DUF1996 PF09362.5 EDN02362.1 - 3.5e-82 275.5 0.2 5e-82 275.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HECT_2 PF09814.4 EDN02363.1 - 1.8e-30 105.8 0.0 2.3e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding HECT_2 PF09814.4 EDN02364.1 - 5.1e-30 104.3 0.0 7.2e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF4243 PF14027.1 EDN02365.1 - 1.3e-86 291.0 2.1 1.6e-86 290.7 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF2516 PF10724.4 EDN02365.1 - 0.1 12.6 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2516) DUF3481 PF11980.3 EDN02365.1 - 0.15 11.8 1.1 10 5.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) DUF3763 PF12592.3 EDN02365.1 - 0.27 10.9 1.2 0.69 9.5 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3763) DEAD PF00270.24 EDN02366.1 - 2.3e-11 43.4 0.0 8.2e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN02366.1 - 7.4e-05 22.6 0.0 0.001 18.9 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA PF00004.24 EDN02370.1 - 1.1e-49 167.9 0.0 5.1e-43 146.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDN02370.1 - 2.9e-06 28.0 0.0 0.0013 19.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN02370.1 - 4.7e-05 22.8 0.3 0.00073 18.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDN02370.1 - 0.00014 20.9 0.0 0.00045 19.3 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EDN02370.1 - 0.0003 20.9 0.0 0.0065 16.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDN02370.1 - 0.00034 20.6 0.1 0.029 14.3 0.0 3.4 1 1 0 2 2 2 1 AAA ATPase domain Parvo_NS1 PF01057.12 EDN02370.1 - 0.00042 19.2 0.0 0.00079 18.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.12 EDN02370.1 - 0.0013 18.1 0.0 0.0029 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EDN02370.1 - 0.0013 18.6 0.0 0.0036 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EDN02370.1 - 0.0017 18.4 0.0 0.013 15.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 EDN02370.1 - 0.0047 16.6 0.0 0.027 14.1 0.0 2.3 2 0 0 2 2 1 1 Part of AAA domain TIP49 PF06068.8 EDN02370.1 - 0.005 15.5 0.0 0.0091 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus KaiC PF06745.8 EDN02370.1 - 0.0082 15.2 0.2 0.073 12.1 0.1 2.4 1 1 1 2 2 2 1 KaiC Mg_chelatase PF01078.16 EDN02370.1 - 0.02 14.0 0.1 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDN02370.1 - 0.022 14.4 0.0 0.066 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EDN02370.1 - 0.026 14.8 0.0 0.095 13.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDN02370.1 - 0.026 14.3 0.0 0.28 11.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.1 EDN02370.1 - 0.039 13.8 0.0 0.26 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EDN02370.1 - 0.04 13.1 0.0 0.084 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 EDN02370.1 - 0.056 12.9 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 EDN02370.1 - 0.061 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 EDN02370.1 - 0.25 9.9 0.0 0.38 9.3 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase BSP_II PF05432.6 EDN02371.1 - 0.0035 16.6 6.8 0.0043 16.3 4.7 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Daxx PF03344.10 EDN02371.1 - 0.0069 14.9 7.7 0.0059 15.1 5.3 1.1 1 0 0 1 1 1 1 Daxx Family Nucleoplasmin PF03066.10 EDN02371.1 - 0.0096 15.4 8.1 0.016 14.7 5.6 1.4 1 0 0 1 1 1 1 Nucleoplasmin DUF3381 PF11861.3 EDN02371.1 - 0.019 14.5 5.9 1.6 8.2 4.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) MYCBPAP PF14646.1 EDN02371.1 - 0.021 13.5 1.1 0.025 13.3 0.7 1.1 1 0 0 1 1 1 0 MYCBP-associated protein family IFT57 PF10498.4 EDN02371.1 - 0.043 12.5 1.6 0.046 12.4 1.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4246 PF14033.1 EDN02371.1 - 0.074 11.6 2.8 0.081 11.5 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) DUF1510 PF07423.6 EDN02371.1 - 0.097 12.0 4.4 0.12 11.7 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM176 PF14851.1 EDN02371.1 - 0.14 11.8 4.0 0.19 11.4 2.8 1.2 1 0 0 1 1 1 0 FAM176 family DUF3682 PF12446.3 EDN02371.1 - 0.15 12.3 9.2 0.28 11.4 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Nop14 PF04147.7 EDN02371.1 - 0.16 9.8 7.3 0.18 9.7 5.0 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 EDN02371.1 - 0.24 10.3 3.7 0.29 10.1 2.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit VID27 PF08553.5 EDN02371.1 - 0.38 8.9 5.5 0.41 8.8 3.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Paf1 PF03985.8 EDN02371.1 - 0.4 9.3 9.3 0.55 8.9 6.4 1.1 1 0 0 1 1 1 0 Paf1 Sigma70_ner PF04546.8 EDN02371.1 - 0.45 10.0 9.2 0.69 9.4 6.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Pox_Ag35 PF03286.9 EDN02371.1 - 0.55 9.7 6.5 0.63 9.5 4.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RXT2_N PF08595.6 EDN02371.1 - 0.63 9.8 5.9 0.95 9.2 4.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Herpes_gE PF02480.11 EDN02371.1 - 0.75 7.9 2.5 0.86 7.7 1.7 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E YqfQ PF14181.1 EDN02371.1 - 1 9.3 3.8 1.5 8.8 2.6 1.4 1 0 0 1 1 1 0 YqfQ-like protein CDC45 PF02724.9 EDN02371.1 - 1.7 6.6 5.7 1.9 6.4 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.13 EDN02371.1 - 1.7 6.9 9.5 2.5 6.3 6.6 1.2 1 0 0 1 1 1 0 Hsp90 protein CobT PF06213.7 EDN02371.1 - 1.8 7.6 11.7 2.4 7.2 8.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFIIF_alpha PF05793.7 EDN02371.1 - 2 6.6 11.5 2.4 6.4 8.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PPP4R2 PF09184.6 EDN02371.1 - 2.2 7.7 13.4 3.1 7.2 9.3 1.2 1 0 0 1 1 1 0 PPP4R2 Nucleo_P87 PF07267.6 EDN02371.1 - 3.7 6.1 8.7 4.7 5.7 6.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NESP55 PF06390.7 EDN02371.1 - 3.9 6.7 20.4 0.44 9.8 0.9 2.1 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Myc_N PF01056.13 EDN02371.1 - 4.9 6.2 11.2 7 5.7 7.7 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Sporozoite_P67 PF05642.6 EDN02371.1 - 5.7 4.6 8.0 7.6 4.2 5.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_RNA_Pol_19 PF05320.7 EDN02371.1 - 9.8 5.9 8.6 14 5.3 6.0 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit HTH_7 PF02796.10 EDN02372.1 - 1.5e-07 31.1 0.0 4.2e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.1 EDN02372.1 - 4.8e-07 29.9 0.0 1.2e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_33 PF13592.1 EDN02372.1 - 1.7e-06 27.4 0.0 4.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EDN02372.1 - 2.2e-06 27.0 0.5 0.00017 21.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 EDN02372.1 - 4.9e-05 22.7 0.0 0.00065 19.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.1 EDN02372.1 - 0.00027 20.8 0.0 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.13 EDN02372.1 - 0.00061 19.4 0.0 0.00099 18.8 0.0 1.4 1 1 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.1 EDN02372.1 - 0.04 14.7 0.0 0.23 12.2 0.0 2.0 1 1 1 2 2 2 0 Homeodomain-like domain HTH_Tnp_IS630 PF01710.11 EDN02372.1 - 0.043 13.4 0.0 0.068 12.8 0.0 1.4 1 1 0 1 1 1 0 Transposase GerE PF00196.14 EDN02372.1 - 0.055 12.7 0.9 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Terminase_5 PF06056.7 EDN02372.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Trp_repressor PF01371.14 EDN02372.1 - 0.12 12.2 0.1 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein Peptidase_S9 PF00326.16 EDN02373.1 - 8.6e-41 139.4 0.0 1.1e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDN02373.1 - 1.3e-07 31.4 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EDN02373.1 - 0.00064 19.2 0.0 0.0084 15.5 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EDN02373.1 - 0.0012 18.7 1.2 0.077 12.8 0.8 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EDN02373.1 - 0.05 12.0 0.7 3.7 5.9 0.0 2.8 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) DLH PF01738.13 EDN02373.1 - 0.19 10.9 0.3 0.64 9.2 0.2 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family PD40 PF07676.7 EDN02374.1 - 4.1e-05 23.1 2.2 0.0042 16.7 0.1 2.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.10 EDN02374.1 - 0.02 13.4 0.0 0.049 12.1 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain zf-C2H2 PF00096.21 EDN02375.1 - 0.00022 21.3 3.9 0.00022 21.3 2.7 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN02375.1 - 0.25 11.7 17.3 0.046 14.0 1.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3818 PF12825.2 EDN02376.1 - 1.7e-138 461.0 3.8 2.4e-138 460.4 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EDN02376.1 - 7.2e-44 148.7 0.6 2e-43 147.2 0.4 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EDN02376.1 - 6.4e-12 45.2 2.1 4.6e-11 42.5 0.0 3.2 3 1 0 3 3 3 1 PX domain DUF2474 PF10617.4 EDN02377.1 - 0.62 9.7 0.3 0.62 9.7 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2474) Met_10 PF02475.11 EDN02379.1 - 3.2e-62 209.6 0.0 6e-62 208.8 0.0 1.4 1 1 0 1 1 1 1 Met-10+ like-protein RNA_pol_Rpb4 PF03874.11 EDN02380.1 - 6.4e-23 80.9 2.9 8.1e-23 80.6 2.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF4102 PF13356.1 EDN02380.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4102) MT-A70 PF05063.9 EDN02380.1 - 0.11 11.9 0.5 0.97 8.9 0.0 2.1 1 1 1 2 2 2 0 MT-A70 DUF2312 PF10073.4 EDN02380.1 - 0.14 11.5 2.2 0.17 11.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) RhoGAP PF00620.22 EDN02381.1 - 8.3e-35 119.6 0.1 1.7e-34 118.6 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EDN02381.1 - 3.7e-28 97.3 34.8 4.6e-12 45.8 4.7 4.9 5 0 0 5 5 5 4 LIM domain Nbl1_Borealin_N PF10444.4 EDN02382.1 - 1.5e-23 81.8 2.1 2.4e-23 81.2 1.4 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.1 EDN02383.1 - 1.5e-07 31.7 0.0 2.4e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EDN02383.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 EDN02383.1 - 0.0035 16.7 0.3 0.0035 16.7 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin interaction motif VWA PF00092.23 EDN02383.1 - 0.029 14.1 0.1 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain RSS_P20 PF11757.3 EDN02383.1 - 0.046 13.8 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like Spc7 PF08317.6 EDN02383.1 - 0.16 10.6 1.3 0.21 10.1 0.3 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Sybindin PF04099.7 EDN02384.1 - 4.9e-46 155.9 0.0 1.3e-42 144.8 0.0 2.2 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EDN02384.1 - 8.9e-08 32.0 0.0 1.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region bZIP_2 PF07716.10 EDN02384.1 - 0.0019 17.9 8.6 0.0036 17.0 6.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EDN02384.1 - 0.0045 16.9 8.9 0.0045 16.9 6.2 1.7 1 1 0 1 1 1 1 bZIP transcription factor DUF745 PF05335.8 EDN02384.1 - 0.21 11.0 0.7 0.33 10.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Methyltransf_31 PF13847.1 EDN02385.1 - 1.8e-22 79.5 0.0 3.1e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN02385.1 - 2.8e-15 56.5 0.0 6.9e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN02385.1 - 5.4e-13 48.9 0.0 1e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN02385.1 - 1.6e-10 40.4 0.1 2.7e-10 39.7 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EDN02385.1 - 3.9e-09 37.0 0.1 9.3e-09 35.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN02385.1 - 8.1e-09 35.7 0.0 3.3e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EDN02385.1 - 1.3e-08 34.3 0.5 2.4e-08 33.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EDN02385.1 - 1.7e-08 34.5 0.1 3.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN02385.1 - 1.8e-07 31.5 0.0 3.4e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDN02385.1 - 3.9e-05 23.2 0.0 6.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EDN02385.1 - 9e-05 21.9 0.1 0.00016 21.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EDN02385.1 - 0.00047 19.3 0.0 0.00065 18.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EDN02385.1 - 0.0026 17.4 0.0 0.0062 16.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EDN02385.1 - 0.0035 16.3 0.1 0.61 8.9 0.0 2.2 1 1 0 2 2 2 2 NNMT/PNMT/TEMT family Met_10 PF02475.11 EDN02385.1 - 0.05 13.1 0.1 0.096 12.2 0.1 1.4 1 0 0 1 1 1 0 Met-10+ like-protein FtsJ PF01728.14 EDN02385.1 - 0.082 12.8 0.1 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase AA_permease_2 PF13520.1 EDN02386.1 - 7.6e-38 130.1 22.8 4.6e-20 71.5 10.6 2.4 1 1 1 2 2 2 2 Amino acid permease DDE_1 PF03184.14 EDN02387.1 - 2.1e-51 174.1 0.0 6.8e-51 172.4 0.0 1.9 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN02387.1 - 3.7e-09 35.9 0.1 8.5e-09 34.8 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN02387.1 - 1.7e-08 34.1 0.1 6e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.1 EDN02387.1 - 0.0054 16.7 0.1 0.017 15.1 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain zf-CCHC_4 PF14392.1 EDN02387.1 - 0.04 13.5 0.5 0.04 13.5 0.3 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EDN02387.1 - 0.05 13.2 0.4 0.45 10.2 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle NUMOD1 PF07453.8 EDN02387.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 NUMOD1 domain zf-CCHC PF00098.18 EDN02387.1 - 0.27 11.2 1.0 0.48 10.4 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle GCR1_C PF12550.3 EDN02388.1 - 1.4e-20 72.8 0.7 4e-20 71.4 0.1 2.0 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes DUF3716 PF12511.3 EDN02388.1 - 0.015 14.8 0.1 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) HTH_7 PF02796.10 EDN02389.1 - 1.3e-07 31.3 0.0 2.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.1 EDN02389.1 - 3.4e-06 27.1 0.0 4.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EDN02389.1 - 2e-05 24.0 0.0 0.0001 21.8 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain PAX PF00292.13 EDN02389.1 - 7.9e-05 22.3 0.0 9.4e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 'Paired box' domain HTH_38 PF13936.1 EDN02389.1 - 0.00013 21.4 0.0 0.00037 19.9 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EDN02389.1 - 0.0034 18.1 0.0 0.022 15.5 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EDN02389.1 - 0.0059 16.5 0.1 0.012 15.5 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.1 EDN02389.1 - 0.049 13.1 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix Terminase_5 PF06056.7 EDN02389.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Trp_repressor PF01371.14 EDN02389.1 - 0.095 12.6 0.1 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Trp repressor protein GerE PF00196.14 EDN02389.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Nucleo_P87 PF07267.6 EDN02390.1 - 0.064 11.9 7.0 0.082 11.5 4.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Nucleoplasmin PF03066.10 EDN02390.1 - 0.41 10.1 4.9 0.74 9.3 3.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin NESP55 PF06390.7 EDN02390.1 - 0.46 9.8 22.0 0.14 11.4 2.1 2.1 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) PBP1_TM PF14812.1 EDN02390.1 - 2.1 8.7 7.7 4.5 7.6 5.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal bZIP_1 PF00170.16 EDN02391.1 - 0.00017 21.4 4.6 0.00032 20.5 3.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor UQ_con PF00179.21 EDN02392.1 - 1.1e-23 83.2 0.0 5.4e-10 38.8 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDN02392.1 - 0.00079 19.1 0.1 0.0025 17.5 0.0 2.0 2 1 0 2 2 2 1 Prokaryotic E2 family B 3Beta_HSD PF01073.14 EDN02393.1 - 3.4e-47 160.4 0.0 5.8e-41 140.0 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDN02393.1 - 1.2e-23 83.7 0.0 1.9e-22 79.9 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EDN02393.1 - 5e-14 51.8 0.0 1.3e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EDN02393.1 - 1.4e-06 28.4 0.0 0.00023 21.1 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EDN02393.1 - 1.6e-06 27.2 0.0 6.3e-05 22.0 0.0 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EDN02393.1 - 0.00037 19.4 0.0 0.74 8.6 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.20 EDN02393.1 - 0.0067 16.3 0.0 0.35 10.7 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EDN02393.1 - 0.17 11.5 0.1 0.61 9.7 0.1 2.1 1 1 0 1 1 1 0 KR domain Pkinase PF00069.20 EDN02394.1 - 1.6e-59 201.1 0.0 1.9e-38 132.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02394.1 - 8.6e-29 100.3 0.0 1.9e-20 73.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EDN02394.1 - 4.9e-11 42.6 0.0 1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EDN02394.1 - 2.3e-06 26.8 0.1 2.9e-05 23.1 0.0 2.4 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EDN02394.1 - 1.9e-05 24.5 0.0 0.0053 16.5 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family PAS PF00989.19 EDN02394.1 - 0.0028 17.4 0.1 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 PAS fold Kdo PF06293.9 EDN02394.1 - 0.0041 16.2 0.0 0.008 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EDN02394.1 - 0.064 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family PAS_9 PF13426.1 EDN02394.1 - 0.078 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 PAS domain Seadorna_VP7 PF07387.6 EDN02394.1 - 0.12 11.2 0.1 0.27 10.0 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 NARP1 PF12569.3 EDN02395.1 - 0.042 12.6 0.1 0.055 12.2 0.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Myb_DNA-bind_6 PF13921.1 EDN02396.1 - 0.0027 17.7 0.2 0.0091 16.0 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain CCDC92 PF14916.1 EDN02396.1 - 1.2 8.7 4.3 6.4 6.4 0.3 2.4 1 1 1 2 2 2 0 Coiled-coil domain of unknown function Pkinase PF00069.20 EDN02397.1 - 6.2e-06 25.5 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EDN02397.1 - 0.00024 20.2 0.0 0.00047 19.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN02397.1 - 0.0035 17.1 3.1 0.0087 15.8 0.1 2.9 2 1 0 3 3 3 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.1 EDN02397.1 - 0.008 15.9 0.0 0.28 11.0 0.0 2.3 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) RIO1 PF01163.17 EDN02397.1 - 0.25 10.6 0.0 0.48 9.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family RVT_1 PF00078.22 EDN02399.1 - 2.9e-29 101.9 0.0 8.2e-29 100.4 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN02399.1 - 2.3e-18 65.9 0.1 8e-18 64.1 0.1 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN02399.1 - 4.2e-18 65.9 0.0 1.2e-17 64.5 0.0 1.8 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN02399.1 - 1.3e-05 24.8 0.0 4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like zf-CCHC PF00098.18 EDN02399.1 - 0.0081 16.0 4.2 0.024 14.5 2.9 1.9 1 0 0 1 1 1 1 Zinc knuckle Lac_bphage_repr PF06543.7 EDN02400.1 - 0.064 12.8 1.3 0.15 11.5 0.5 1.9 2 0 0 2 2 2 0 Lactococcus bacteriophage repressor DUF3723 PF12520.3 EDN02401.1 - 1.5e-19 69.9 0.1 1.4e-09 37.0 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) DUF3435 PF11917.3 EDN02402.1 - 1.8e-146 488.1 4.1 2.6e-94 316.3 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EDN02402.1 - 0.002 17.8 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 Phage integrase family OmpH PF03938.9 EDN02402.1 - 0.02 14.8 1.7 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) eIF-3_zeta PF05091.7 EDN02403.1 - 3e-199 662.9 0.0 3.5e-199 662.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AflR PF08493.5 EDN02404.1 - 0.54 9.2 7.7 0.16 10.9 3.3 1.5 2 0 0 2 2 2 0 Aflatoxin regulatory protein Amidase PF01425.16 EDN02406.1 - 9.1e-87 291.7 0.0 1.2e-86 291.3 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF3546 PF12066.3 EDN02408.1 - 1.5e-28 98.9 3.1 1.5e-28 98.9 2.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 EDN02408.1 - 6.5e-25 86.4 0.1 1.4e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 EDN02408.1 - 3.9e-09 37.0 0.3 9.1e-09 35.8 0.2 1.6 1 1 0 1 1 1 1 Arsenite-resistance protein 2 Glyco_transf_90 PF05686.7 EDN02409.1 - 1.6e-28 99.4 1.0 2.5e-28 98.8 0.7 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EDN02409.1 - 8.1e-05 22.8 0.1 0.00017 21.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2531 PF10748.4 EDN02409.1 - 0.048 12.8 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2531) Cu-oxidase_3 PF07732.10 EDN02410.1 - 3.5e-10 39.6 0.3 4e-07 29.7 0.1 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EDN02410.1 - 3.7e-07 29.7 0.1 0.028 13.9 0.0 3.0 3 0 0 3 3 3 2 Multicopper oxidase Kinesin PF00225.18 EDN02411.1 - 1.5e-111 372.3 0.0 2.3e-111 371.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EDN02411.1 - 8.1e-44 148.6 0.0 1.7e-43 147.6 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein KIF1B PF12423.3 EDN02411.1 - 8.7e-07 28.8 0.3 2.5e-06 27.4 0.2 1.9 1 0 0 1 1 1 1 Kinesin protein 1B PH PF00169.24 EDN02411.1 - 6.4e-06 26.3 0.0 1.9e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 PH domain Tmemb_cc2 PF10267.4 EDN02411.1 - 0.0062 15.1 3.8 0.046 12.3 0.5 2.2 2 0 0 2 2 2 2 Predicted transmembrane and coiled-coil 2 protein RVT_1 PF00078.22 EDN02413.1 - 1.1e-28 100.0 0.0 1.8e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN02413.1 - 1.1e-12 47.5 0.0 2.5e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN02413.1 - 1.1e-06 28.9 0.0 3e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 RNase H AIF_C PF14721.1 EDN02415.1 - 0.036 14.3 1.6 0.04 14.1 1.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PPO1_KFDV PF12143.3 EDN02415.1 - 0.096 12.5 1.1 0.11 12.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF_B2219) STAG PF08514.6 EDN02415.1 - 0.12 12.1 2.7 0.15 11.8 1.8 1.2 1 0 0 1 1 1 0 STAG domain TMCO5 PF14992.1 EDN02415.1 - 0.15 11.2 6.8 0.15 11.1 4.7 1.0 1 0 0 1 1 1 0 TMCO5 family GLYCAM-1 PF05242.6 EDN02415.1 - 0.25 11.2 4.6 0.28 11.1 3.2 1.1 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Peptidase_S49_N PF08496.5 EDN02415.1 - 1.5 8.6 7.7 1.7 8.3 5.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RVT_1 PF00078.22 EDN02416.1 - 1.4e-21 76.8 0.1 3e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN02416.1 - 1.2e-17 64.1 0.4 3.5e-17 62.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EDN02416.1 - 3.6e-13 48.9 1.0 8.6e-13 47.7 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EDN02416.1 - 0.00015 21.0 0.1 0.00045 19.5 0.0 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Tudor-knot PF11717.3 EDN02416.1 - 0.0032 17.1 0.4 0.029 14.0 0.0 2.6 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain RVP PF00077.15 EDN02416.1 - 0.018 14.9 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EDN02416.1 - 0.071 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDN02416.1 - 0.17 12.3 0.0 0.37 11.3 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.6 EDN02416.1 - 0.19 11.6 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Ring_hydroxyl_A PF00848.14 EDN02419.1 - 4.2e-21 75.5 5.4 1.6e-14 54.0 0.0 2.8 2 1 1 3 3 3 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EDN02419.1 - 3.5e-16 58.5 0.0 7.9e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain AA_permease_2 PF13520.1 EDN02421.1 - 1.5e-60 204.9 50.9 1.8e-60 204.6 35.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN02421.1 - 6.2e-26 90.7 41.0 8.2e-26 90.3 28.4 1.1 1 0 0 1 1 1 1 Amino acid permease Tmemb_18A PF09771.4 EDN02421.1 - 0.85 9.5 5.9 69 3.4 0.4 4.0 4 0 0 4 4 4 0 Transmembrane protein 188 Gram_pos_anchor PF00746.16 EDN02421.1 - 1.1 9.1 0.0 1.1 9.1 0.0 3.6 3 0 0 3 3 3 0 Gram positive anchor Fungal_trans_2 PF11951.3 EDN02422.1 - 4e-54 183.6 1.7 8.7e-54 182.5 1.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN02422.1 - 2.1e-05 24.3 3.3 5.2e-05 23.0 2.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sad1_UNC PF07738.8 EDN02423.1 - 1.7e-12 47.2 0.0 5.1e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal CytochromB561_N PF09786.4 EDN02423.1 - 0.35 9.2 9.6 0.0054 15.2 1.4 1.6 2 0 0 2 2 2 0 Cytochrome B561, N terminal WD40 PF00400.27 EDN02424.1 - 9e-38 126.8 6.0 3.7e-10 39.2 0.2 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EDN02424.1 - 4.1e-07 28.5 9.3 0.06 11.4 0.4 4.9 2 2 2 5 5 5 4 Nucleoporin Nup120/160 ADH_zinc_N PF00107.21 EDN02424.1 - 0.068 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PQQ_2 PF13360.1 EDN02424.1 - 0.075 12.4 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 PQQ-like domain DUF3883 PF13020.1 EDN02425.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) CM_2 PF01817.16 EDN02426.1 - 2.2e-07 30.8 0.3 7e-05 22.8 0.0 3.2 2 1 0 2 2 2 2 Chorismate mutase type II BCIP PF13862.1 EDN02427.1 - 2e-71 239.5 0.2 2.6e-71 239.1 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein RVT_1 PF00078.22 EDN02428.1 - 9e-35 119.9 0.0 1.8e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN02428.1 - 2.1e-15 56.3 0.0 1e-14 54.1 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN02428.1 - 0.00055 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EDN02428.1 - 0.00057 19.6 4.1 0.00057 19.6 2.9 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 EDN02428.1 - 1 9.0 12.8 3.3 7.4 1.0 2.7 1 1 1 2 2 2 0 Zinc knuckle APH PF01636.18 EDN02429.1 - 1.1e-09 38.3 0.0 9e-09 35.4 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN02429.1 - 0.0058 16.2 0.0 0.0084 15.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase zf-C2H2_6 PF13912.1 EDN02431.1 - 0.00048 19.9 9.8 0.0087 15.9 0.4 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EDN02431.1 - 0.00075 19.5 0.5 0.58 10.2 0.0 2.2 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EDN02431.1 - 0.00093 19.3 3.2 0.016 15.4 0.2 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EDN02431.1 - 0.017 15.4 9.9 2 8.9 0.1 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EDN02431.1 - 0.11 12.6 5.4 15 5.8 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EDN02431.1 - 0.28 11.6 7.2 17 5.9 0.0 4.0 3 1 0 3 3 3 0 C2H2-type zinc finger Inhibitor_I67 PF11405.3 EDN02431.1 - 0.43 10.6 3.0 1.3 9.1 2.1 1.7 1 1 0 1 1 1 0 Bromelain inhibitor VI Kdo PF06293.9 EDN02433.1 - 0.002 17.2 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NmrA PF05368.8 EDN02436.1 - 0.005 16.1 0.2 0.027 13.7 0.1 1.9 1 1 0 1 1 1 1 NmrA-like family Apt1 PF10351.4 EDN02436.1 - 0.034 13.0 0.8 0.047 12.5 0.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3744 PF12558.3 EDN02437.1 - 0.063 13.7 0.1 0.13 12.7 0.0 1.5 2 0 0 2 2 2 0 ATP-binding cassette cobalt transporter BCS1_N PF08740.6 EDN02439.1 - 1.2e-13 51.1 0.1 1.4e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 BCS1 N terminal Aa_trans PF01490.13 EDN02444.1 - 7.1e-28 97.2 32.2 8.7e-28 96.9 22.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EDN02444.1 - 2.3e-05 23.1 26.2 2.3e-05 23.1 18.2 2.1 1 1 1 2 2 2 2 Amino acid permease Hydantoinase_A PF01968.13 EDN02446.1 - 2.5e-81 272.9 8.3 6.3e-81 271.6 1.7 2.7 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.9 EDN02446.1 - 7.6e-66 222.4 0.0 1.5e-65 221.4 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.8 EDN02446.1 - 8.3e-43 145.9 1.1 4.1e-40 137.1 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EDN02446.1 - 2.8e-06 25.9 0.9 0.0088 14.4 0.1 2.4 2 0 0 2 2 2 2 MutL protein Rop-like PF05082.8 EDN02446.1 - 0.047 13.1 0.1 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Rop-like BcrAD_BadFG PF01869.15 EDN02446.1 - 0.1 11.8 0.8 0.35 10.1 0.1 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 EDN02446.1 - 0.36 10.6 6.2 1.7 8.4 0.3 3.0 3 0 0 3 3 3 0 Cell division protein FtsA Tektin PF03148.9 EDN02446.1 - 0.42 9.0 0.3 0.71 8.3 0.2 1.2 1 0 0 1 1 1 0 Tektin family DDE_Tnp_1_7 PF13843.1 EDN02451.1 - 0.0015 17.6 0.2 0.0015 17.6 0.1 1.2 1 1 0 1 1 1 1 Transposase IS4 Kinesin PF00225.18 EDN02453.1 - 8.6e-81 271.2 0.1 8.6e-81 271.2 0.1 3.9 4 1 0 4 4 4 1 Kinesin motor domain DUF812 PF05667.6 EDN02453.1 - 0.001 17.6 31.6 0.001 17.6 21.9 7.1 3 2 4 7 7 7 1 Protein of unknown function (DUF812) Glycos_transf_1 PF00534.15 EDN02454.1 - 1.4e-28 99.4 0.8 1.7e-27 95.9 0.5 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EDN02454.1 - 2.9e-10 40.1 0.0 0.00018 21.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EDN02454.1 - 5.8e-09 36.2 0.7 4e-08 33.5 0.5 2.1 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EDN02454.1 - 8.4e-08 32.4 0.1 1.3e-05 25.3 0.0 2.4 1 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EDN02454.1 - 0.0008 19.6 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF4611 PF15387.1 EDN02454.1 - 0.044 13.9 0.2 0.099 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Peptidase_M16_C PF05193.16 EDN02457.1 - 2.4e-33 115.3 0.0 1.7e-22 80.0 0.0 3.7 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EDN02457.1 - 1e-27 96.6 10.3 2.5e-21 75.9 0.7 3.5 4 0 0 4 4 4 2 Insulinase (Peptidase family M16) DBR1 PF05011.8 EDN02458.1 - 7.3e-51 171.8 0.0 7.3e-51 171.8 0.0 2.1 3 0 0 3 3 3 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EDN02458.1 - 3.4e-05 23.3 0.5 6.2e-05 22.4 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2435 PF10363.4 EDN02459.1 - 1.2e-26 92.3 0.2 4.5e-25 87.3 0.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EDN02459.1 - 2.8e-11 42.6 0.0 7.3e-11 41.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) Polysacc_deac_1 PF01522.16 EDN02460.1 - 3.8e-28 97.5 0.0 6e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Clathrin PF00637.15 EDN02463.1 - 1.1e-21 76.9 5.7 2.4e-19 69.3 2.6 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-RING_5 PF14634.1 EDN02463.1 - 6.4e-05 22.5 7.6 0.00013 21.5 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDN02463.1 - 0.00016 21.5 7.2 0.00035 20.5 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) VPS11_C PF12451.3 EDN02463.1 - 0.00018 21.2 0.1 0.00046 19.9 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 EDN02463.1 - 0.0011 18.7 8.7 0.0021 17.8 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDN02463.1 - 0.0034 17.4 2.2 0.007 16.4 1.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger TPR_11 PF13414.1 EDN02463.1 - 0.0042 16.7 0.3 0.033 13.8 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.1 EDN02463.1 - 0.013 16.0 0.1 4.4 8.2 0.0 4.5 6 0 0 6 6 4 0 Tetratricopeptide repeat Leuk-A4-hydro_C PF09127.6 EDN02463.1 - 0.092 12.3 1.1 0.43 10.1 0.1 2.2 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal zf-Apc11 PF12861.2 EDN02463.1 - 0.1 12.4 1.1 0.33 10.8 0.8 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EDN02463.1 - 0.12 12.0 7.4 0.24 11.1 5.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EDN02463.1 - 0.13 12.0 1.4 0.33 10.7 1.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TPR_2 PF07719.12 EDN02463.1 - 0.17 11.8 0.1 0.17 11.8 0.1 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.1 EDN02463.1 - 0.55 10.1 5.5 1.4 8.8 3.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_12 PF13424.1 EDN02463.1 - 0.83 9.6 12.7 0.61 10.0 0.4 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDN02463.1 - 4.2 7.1 5.9 4.6 7.0 0.3 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat LRR_4 PF12799.2 EDN02464.1 - 3.1e-32 109.6 30.6 4.1e-08 32.6 0.5 8.2 5 3 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDN02464.1 - 1.2e-22 79.3 34.4 6.3e-08 32.2 0.1 7.2 4 1 4 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 EDN02464.1 - 6.9e-14 49.7 31.3 0.088 12.8 0.0 11.9 11 1 1 12 12 12 7 Leucine Rich Repeat LRR_6 PF13516.1 EDN02464.1 - 4.8e-07 29.1 23.7 0.31 11.2 0.1 9.6 8 1 1 9 9 9 3 Leucine Rich repeat LRR_9 PF14580.1 EDN02464.1 - 1.8e-06 27.6 6.5 0.00059 19.4 0.5 3.7 2 1 2 4 4 4 2 Leucine-rich repeat LRR_7 PF13504.1 EDN02464.1 - 3.7e-06 26.2 33.1 1.2 9.6 0.1 11.0 9 1 1 10 10 10 2 Leucine rich repeat IPK PF03770.11 EDN02465.1 - 2.5e-57 193.7 0.0 4e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 EDN02465.1 - 0.029 14.0 0.1 0.098 12.3 0.0 1.9 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 MFS_1 PF07690.11 EDN02466.1 - 7.7e-17 61.0 16.4 1.6e-16 59.9 11.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EDN02466.1 - 1.4e-06 27.7 6.3 1.6e-06 27.5 1.0 2.2 2 0 0 2 2 2 1 Nodulin-like ERCC4 PF02732.10 EDN02467.1 - 1.1e-22 80.3 0.0 8.5e-21 74.2 0.0 2.5 1 1 0 1 1 1 1 ERCC4 domain CAF-1_p150 PF11600.3 EDN02467.1 - 0.099 12.0 17.8 0.27 10.5 12.3 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RVT_1 PF00078.22 EDN02469.1 - 1.6e-26 92.9 0.0 3.4e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN02469.1 - 1.2e-17 64.1 0.1 5.7e-17 61.9 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EDN02469.1 - 1.7e-13 50.0 2.5 2.3e-13 49.5 0.7 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EDN02469.1 - 0.036 13.4 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger Mtf2_C PF14061.1 EDN02469.1 - 0.063 13.1 0.5 0.17 11.8 0.1 1.8 1 1 1 2 2 2 0 Polycomb-like MTF2 factor 2 Tmemb_9 PF05434.6 EDN02470.1 - 0.035 13.8 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 TMEM9 Apis_Csd PF11671.3 EDN02470.1 - 0.043 13.6 2.7 0.045 13.5 1.9 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein PRA1 PF03208.14 EDN02470.1 - 1.8 7.9 6.2 2.2 7.6 4.3 1.1 1 0 0 1 1 1 0 PRA1 family protein GerA PF03323.8 EDN02471.1 - 0.023 12.8 0.5 0.032 12.3 0.3 1.2 1 1 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein TSCPD PF12637.2 EDN02472.1 - 0.084 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 TSCPD domain NUDIX_2 PF13869.1 EDN02473.1 - 2.6e-82 274.7 0.0 3.2e-82 274.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase DUF4316 PF14195.1 EDN02473.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) zf-CHCC PF10276.4 EDN02474.1 - 2.1e-15 56.2 2.0 2.1e-15 56.2 1.4 2.0 2 0 0 2 2 2 1 Zinc-finger domain CoaE PF01121.15 EDN02475.1 - 1.3e-40 138.6 0.0 4.9e-21 74.9 0.0 2.2 2 0 0 2 2 2 2 Dephospho-CoA kinase AAA_17 PF13207.1 EDN02475.1 - 0.00014 22.6 0.1 0.00032 21.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDN02475.1 - 0.00026 20.9 0.1 0.0044 16.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain DUF393 PF04134.7 EDN02475.1 - 0.068 14.2 2.7 0.15 13.1 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF393 AAA_18 PF13238.1 EDN02475.1 - 0.14 12.4 0.0 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain TPR_10 PF13374.1 EDN02475.1 - 0.48 10.4 3.3 0.41 10.6 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3431 PF11913.3 EDN02476.1 - 1.9e-92 308.7 0.1 1.3e-91 306.0 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3431) IncA PF04156.9 EDN02476.1 - 0.47 10.0 0.0 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 IncA protein ECH PF00378.15 EDN02477.1 - 1.1e-46 158.9 0.0 2.9e-46 157.5 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pyr_redox_3 PF13738.1 EDN02478.1 - 5.2e-23 82.1 0.0 1.3e-22 80.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDN02478.1 - 2e-16 59.3 0.1 1.9e-15 56.1 0.0 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EDN02478.1 - 4.3e-09 35.7 0.0 1.2e-05 24.4 0.0 3.2 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EDN02478.1 - 7.4e-06 25.8 0.5 2.8e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EDN02478.1 - 0.00055 19.7 0.5 0.031 14.0 0.0 3.2 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDN02478.1 - 0.00058 19.7 0.0 0.18 11.6 0.0 3.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Ribophorin_I PF04597.9 EDN02478.1 - 0.1 11.0 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribophorin I Fungal_trans PF04082.13 EDN02479.1 - 2.8e-14 52.6 0.1 4.5e-14 51.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Exo_endo_phos PF03372.18 EDN02480.1 - 3.2e-21 76.4 0.0 5.8e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PQQ_3 PF13570.1 EDN02480.1 - 2.6 8.4 6.6 8 6.8 0.1 4.2 4 0 0 4 4 4 0 PQQ-like domain zf-CHY PF05495.7 EDN02482.1 - 2.2e-13 50.1 20.5 2.9e-13 49.7 14.2 1.1 1 0 0 1 1 1 1 CHY zinc finger Cytochrome_C7 PF14522.1 EDN02482.1 - 0.33 10.6 13.5 0.5 10.0 9.4 1.3 1 0 0 1 1 1 0 Cytochrome c7 DUF3797 PF12677.2 EDN02482.1 - 0.97 9.1 0.0 0.97 9.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) C1_4 PF07975.7 EDN02482.1 - 2.3 8.2 16.3 8.1 6.5 5.6 2.5 1 1 2 3 3 3 0 TFIIH C1-like domain HypA PF01155.14 EDN02482.1 - 2.6 7.7 12.5 19 4.9 8.7 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 EDN02482.1 - 4.9 7.2 13.0 0.98 9.4 4.7 2.6 1 1 1 2 2 2 0 zinc-finger Proteasome PF00227.21 EDN02483.1 - 9.8e-55 184.7 0.0 1.3e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDN02483.1 - 2.6e-13 49.0 0.1 2.6e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.7 EDN02483.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) AMP-binding PF00501.23 EDN02484.1 - 3.1e-30 104.9 0.1 1.7e-27 95.8 0.0 2.1 1 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EDN02484.1 - 4.5e-05 24.3 0.3 0.00011 23.0 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Rtt106 PF08512.7 EDN02484.1 - 0.092 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Histone chaperone Rttp106-like FAD-oxidase_C PF02913.14 EDN02485.1 - 5e-60 202.8 0.0 6.9e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EDN02485.1 - 1.4e-34 118.5 0.3 2.7e-34 117.6 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pkinase PF00069.20 EDN02486.1 - 1.1e-70 237.8 0.0 1.6e-70 237.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02486.1 - 1.7e-47 161.7 0.0 2.8e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN02486.1 - 1.7e-06 27.1 0.0 3.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDN02486.1 - 0.018 14.7 0.0 2.1 8.0 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ku_PK_bind PF08785.6 EDN02487.1 - 0.055 13.3 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Ku C terminal domain like p450 PF00067.17 EDN02488.1 - 1.1e-60 205.4 0.0 1.4e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_19 PF13245.1 EDN02488.1 - 0.026 14.2 0.0 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain Acetyltransf_10 PF13673.1 EDN02489.1 - 7.6e-08 32.4 0.0 1.6e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN02489.1 - 1.2e-06 28.4 0.0 2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN02489.1 - 6.8e-06 26.1 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDN02489.1 - 0.0001 22.1 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDN02489.1 - 0.058 13.1 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 EDN02489.1 - 0.1 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4048 PF13257.1 EDN02491.1 - 2.4e-89 299.3 25.6 2.4e-89 299.3 17.7 2.9 4 1 0 4 4 4 1 Domain of unknown function (DUF4048) TPD52 PF04201.10 EDN02491.1 - 0.015 15.0 0.5 0.028 14.1 0.3 1.4 1 0 0 1 1 1 0 Tumour protein D52 family IFP_35_N PF07334.8 EDN02491.1 - 0.12 12.3 4.3 0.083 12.8 0.3 2.6 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF3782 PF12644.2 EDN02491.1 - 0.14 11.9 0.7 0.37 10.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Tim17 PF02466.14 EDN02492.1 - 2.2e-50 170.0 6.4 2.2e-50 170.0 4.5 1.9 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Fer4_13 PF13370.1 EDN02492.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain DUF543 PF04418.7 EDN02492.1 - 1 9.3 5.2 0.68 9.9 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF543) Oxidored_molyb PF00174.14 EDN02493.1 - 4.8e-54 182.2 0.0 7.5e-54 181.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Tim17 PF02466.14 EDN02493.1 - 2.4e-49 166.6 6.4 2.4e-49 166.6 4.5 2.7 3 0 0 3 3 3 1 Tim17/Tim22/Tim23/Pmp24 family NAD_binding_10 PF13460.1 EDN02494.1 - 1e-08 35.3 0.1 1.5e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EDN02494.1 - 0.03 14.2 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF3435 PF11917.3 EDN02495.1 - 3.1e-167 556.5 0.5 4.2e-167 556.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EDN02495.1 - 5.4e-06 26.1 0.1 0.00068 19.3 0.0 2.4 2 0 0 2 2 2 2 Phage integrase family OmpH PF03938.9 EDN02495.1 - 0.37 10.7 8.9 0.43 10.4 0.0 2.7 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Acyl_transf_3 PF01757.17 EDN02496.1 - 1.2e-09 37.4 1.4 1.5e-09 37.2 1.0 1.0 1 0 0 1 1 1 1 Acyltransferase family DUF1624 PF07786.7 EDN02496.1 - 0.0056 16.0 0.5 0.011 15.0 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1624) F-box-like PF12937.2 EDN02498.1 - 6.6e-06 25.7 0.1 1.4e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like DUF1580 PF07618.6 EDN02498.1 - 7.2 6.0 6.1 0.76 9.1 0.2 2.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1580) APH PF01636.18 EDN02500.1 - 2.9e-12 46.8 0.0 1.3e-11 44.7 0.0 2.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family EcKinase PF02958.15 EDN02500.1 - 0.00096 18.3 0.0 0.016 14.3 0.0 2.1 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.15 EDN02500.1 - 0.0025 17.4 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EDN02500.1 - 0.023 13.3 0.0 0.25 9.9 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1679) Pkinase PF00069.20 EDN02501.1 - 3.4e-05 23.1 0.1 0.00066 18.9 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Lac_bphage_repr PF06543.7 EDN02502.1 - 0.14 11.6 2.4 0.33 10.4 1.7 1.5 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor SurA_N_3 PF13624.1 EDN02504.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain BCS1_N PF08740.6 EDN02507.1 - 4.5e-41 140.5 0.1 7.2e-41 139.8 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN02507.1 - 1.3e-19 70.6 0.0 5.3e-19 68.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN02507.1 - 0.00056 19.9 0.5 0.0018 18.3 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EDN02507.1 - 0.0049 17.6 0.0 0.037 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN02507.1 - 0.0087 15.4 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDN02507.1 - 0.041 13.6 0.0 0.1 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN02507.1 - 0.042 13.9 0.0 0.19 11.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EDN02507.1 - 0.045 13.6 0.1 0.42 10.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EDN02507.1 - 0.069 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 EDN02507.1 - 0.074 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 EDN02507.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Myb_DNA-binding PF00249.26 EDN02508.1 - 5.9e-10 39.0 0.0 1.3e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN02508.1 - 3.9e-06 26.8 0.2 9.2e-06 25.6 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain AAA_assoc PF14363.1 EDN02509.1 - 0.082 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA zf-C3HC4_3 PF13920.1 EDN02511.1 - 0.00049 19.6 9.5 0.00076 19.0 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN02511.1 - 0.00066 19.2 3.6 0.0015 18.1 2.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DegS PF05384.6 EDN02511.1 - 0.0028 16.9 0.7 0.0041 16.3 0.5 1.2 1 0 0 1 1 1 1 Sensor protein DegS Sec2p PF06428.6 EDN02511.1 - 0.0083 15.9 1.1 0.013 15.3 0.8 1.3 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p zf-RING_2 PF13639.1 EDN02511.1 - 0.015 15.0 8.7 0.037 13.8 6.0 1.6 1 1 0 1 1 1 0 Ring finger domain HAUS5 PF14817.1 EDN02511.1 - 0.024 13.2 0.2 0.028 13.0 0.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Med28 PF11594.3 EDN02511.1 - 0.028 14.6 0.2 0.043 14.0 0.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 28 HALZ PF02183.13 EDN02511.1 - 0.031 13.9 3.4 0.19 11.4 0.3 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper ADIP PF11559.3 EDN02511.1 - 0.037 13.9 0.9 0.052 13.4 0.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 EDN02511.1 - 0.038 13.9 1.3 0.064 13.2 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) zf-RING_5 PF14634.1 EDN02511.1 - 0.045 13.4 10.5 0.077 12.7 7.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDN02511.1 - 0.049 13.6 9.0 0.095 12.7 6.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ERM PF00769.14 EDN02511.1 - 0.068 12.6 2.2 0.096 12.2 1.5 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF2730 PF10805.3 EDN02511.1 - 0.11 12.1 0.2 0.34 10.6 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) RmuC PF02646.11 EDN02511.1 - 0.14 10.9 0.7 0.19 10.5 0.5 1.1 1 0 0 1 1 1 0 RmuC family IncA PF04156.9 EDN02511.1 - 0.33 10.5 1.6 0.46 10.0 1.1 1.2 1 0 0 1 1 1 0 IncA protein Myb_DNA-bind_6 PF13921.1 EDN02512.1 - 0.002 18.1 0.1 0.0037 17.3 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN02512.1 - 0.016 15.2 0.1 0.032 14.2 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF4244 PF14029.1 EDN02512.1 - 0.036 13.1 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) Myb_DNA-bind_6 PF13921.1 EDN02513.1 - 0.002 18.2 0.1 0.0036 17.3 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN02513.1 - 0.015 15.3 0.1 0.031 14.3 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF4244 PF14029.1 EDN02513.1 - 0.036 13.1 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) DUF3435 PF11917.3 EDN02515.1 - 4.4e-160 532.9 0.0 6.3e-160 532.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) TPR_12 PF13424.1 EDN02515.1 - 2.3e-150 488.8 24.0 2.3e-19 69.0 0.1 7.6 1 1 9 10 10 10 10 Tetratricopeptide repeat TPR_10 PF13374.1 EDN02515.1 - 4.3e-123 398.2 13.6 4.9e-12 45.3 0.1 12.0 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_7 PF13176.1 EDN02515.1 - 7.3e-50 162.8 3.6 0.00096 18.7 0.0 12.2 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_11 PF13414.1 EDN02515.1 - 6.5e-39 131.4 2.4 2e-07 30.5 0.0 6.8 2 2 5 8 8 8 8 TPR repeat TPR_1 PF00515.23 EDN02515.1 - 2.3e-37 125.0 17.5 0.0047 16.4 0.1 11.5 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 EDN02515.1 - 2.7e-30 101.7 17.4 0.084 12.8 0.0 12.4 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_16 PF13432.1 EDN02515.1 - 9e-28 96.3 6.6 0.00013 22.5 0.1 7.7 5 1 2 7 7 7 6 Tetratricopeptide repeat TPR_4 PF07721.9 EDN02515.1 - 3.3e-21 73.4 2.0 1.3 9.6 0.0 10.9 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 EDN02515.1 - 5.5e-20 69.8 0.1 5.1 7.5 0.0 10.8 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN02515.1 - 1.1e-19 69.0 7.2 0.85 10.4 0.1 12.1 10 2 2 12 12 11 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDN02515.1 - 8.7e-19 65.8 15.0 1 9.3 0.0 11.9 11 0 0 11 11 11 2 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 EDN02515.1 - 1.6e-14 53.4 0.1 5.1e-14 51.8 0.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily Apc3 PF12895.2 EDN02515.1 - 1.4e-12 47.5 0.0 0.32 11.1 0.0 6.1 1 1 5 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EDN02515.1 - 3.1e-11 43.4 13.7 0.12 12.7 0.3 7.6 4 1 4 8 8 8 3 Tetratricopeptide repeat Rab5-bind PF09311.6 EDN02515.1 - 6.1e-09 36.0 2.0 0.64 9.8 0.0 6.7 1 1 5 6 6 6 2 Rabaptin-like protein TPR_3 PF07720.7 EDN02515.1 - 1.4e-08 34.3 0.1 66 3.4 0.0 8.9 10 0 0 10 10 10 0 Tetratricopeptide repeat DUF1925 PF09094.6 EDN02515.1 - 3.2e-08 33.4 0.1 1.2e+02 2.8 0.0 9.3 10 0 0 10 10 9 0 Domain of unknown function (DUF1925) PPR PF01535.15 EDN02515.1 - 1.4e-07 31.0 7.9 30 4.8 0.0 9.4 13 0 0 13 13 10 0 PPR repeat Atu4866 PF11512.3 EDN02515.1 - 1.8e-07 30.8 11.5 4 7.2 0.0 7.4 9 1 0 9 9 6 2 Agrobacterium tumefaciens protein Atu4866 Tcf25 PF04910.9 EDN02515.1 - 8.2e-06 25.0 0.0 6.3 5.6 0.0 5.6 2 2 3 6 6 6 0 Transcriptional repressor TCF25 NACHT PF05729.7 EDN02515.1 - 2.1e-05 24.2 0.0 4.8e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain nec1 PF10379.4 EDN02515.1 - 9.9e-05 21.6 0.1 35 3.6 0.0 6.4 1 1 5 7 7 7 0 Virulence protein nec1 NB-ARC PF00931.17 EDN02515.1 - 0.0027 16.6 0.0 0.0062 15.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 EDN02515.1 - 0.0032 17.3 0.0 0.0074 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain MIT PF04212.13 EDN02515.1 - 0.0044 16.8 2.7 54 3.7 0.0 5.5 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 EDN02515.1 - 0.0061 16.6 0.0 0.029 14.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain Nipped-B_C PF12830.2 EDN02515.1 - 0.046 13.3 1.1 2.4 7.7 0.1 2.4 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus Pkinase PF00069.20 EDN02516.1 - 0.0014 17.7 0.0 0.0014 17.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Spore_coat_CotO PF14153.1 EDN02516.1 - 0.0058 16.0 2.5 0.0097 15.3 1.8 1.3 1 0 0 1 1 1 1 Spore coat protein CotO DUF1675 PF07897.6 EDN02516.1 - 0.024 14.5 5.5 0.041 13.7 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) APH PF01636.18 EDN02516.1 - 0.1 12.3 0.1 0.1 12.3 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family RR_TM4-6 PF06459.7 EDN02516.1 - 0.29 11.0 4.4 0.41 10.4 3.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AIF_C PF14721.1 EDN02516.1 - 2.9 8.1 5.3 11 6.2 3.7 1.9 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Myb_DNA-binding PF00249.26 EDN02517.1 - 1.3e-11 44.2 0.3 5.9e-10 39.0 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN02517.1 - 2.1e-07 30.9 1.0 1.7e-06 28.0 0.2 2.3 1 1 1 2 2 2 1 Myb-like DNA-binding domain BCS1_N PF08740.6 EDN02518.1 - 6.9e-40 136.6 0.1 1.1e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN02518.1 - 1.3e-19 70.6 0.0 5.3e-19 68.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN02518.1 - 0.00044 20.2 0.5 0.0012 18.8 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EDN02518.1 - 0.0071 17.1 0.0 0.045 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN02518.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDN02518.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN02518.1 - 0.062 13.4 0.0 0.24 11.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EDN02518.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 EDN02518.1 - 0.089 12.5 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EDN02518.1 - 0.098 12.5 0.1 0.49 10.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EDN02518.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus FKBP_C PF00254.23 EDN02519.1 - 2.6e-19 69.0 0.0 5.7e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DDE_1 PF03184.14 EDN02521.1 - 7.8e-37 126.5 0.0 1.3e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1675 PF07897.6 EDN02521.1 - 6.3 6.5 12.5 9.1 6.0 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PALP PF00291.20 EDN02522.1 - 7.9e-62 209.2 0.2 9.3e-62 208.9 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Cnd3 PF12719.2 EDN02523.1 - 4e-100 334.6 0.1 1.9e-99 332.4 0.0 2.1 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EDN02523.1 - 3.5e-09 36.8 7.5 2.3e-05 24.5 0.2 5.0 4 2 1 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 EDN02523.1 - 5.5e-05 23.5 3.4 0.0033 17.8 0.3 4.4 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.17 EDN02523.1 - 0.0078 16.2 8.2 0.068 13.2 0.0 5.0 7 0 0 7 7 7 1 HEAT repeat RICTOR_N PF14664.1 EDN02523.1 - 0.018 13.6 0.0 0.077 11.5 0.0 2.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term MMS19_N PF14500.1 EDN02523.1 - 0.059 12.6 0.2 0.9 8.7 0.0 2.7 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II zf-RanBP PF00641.13 EDN02524.1 - 1.5e-20 71.9 8.3 5.6e-11 41.3 1.1 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RNase_T PF00929.19 EDN02524.1 - 4.4e-06 27.0 0.0 7.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DZR PF12773.2 EDN02524.1 - 0.99 9.2 8.7 0.63 9.9 0.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon F-box-like PF12937.2 EDN02525.1 - 4.9e-10 38.9 2.5 1.4e-09 37.5 1.8 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EDN02525.1 - 0.00086 18.8 2.2 0.45 10.2 0.4 2.8 2 0 0 2 2 2 2 F-box domain LRR_8 PF13855.1 EDN02525.1 - 0.37 10.5 5.6 0.33 10.7 0.5 2.9 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 EDN02525.1 - 0.43 10.2 7.5 1.9 8.2 0.0 4.3 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) SKG6 PF08693.5 EDN02526.1 - 4.2e-06 25.9 0.0 1.1e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EDN02526.1 - 0.086 12.3 0.3 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) HTH_Tnp_Tc5 PF03221.11 EDN02527.1 - 1.7e-10 40.5 0.1 3.2e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN02527.1 - 1.2e-06 27.9 0.1 1.2e-06 27.9 0.1 1.7 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_1 PF01527.15 EDN02527.1 - 0.023 14.6 0.3 0.073 13.0 0.0 2.0 2 0 0 2 2 2 0 Transposase AAA_27 PF13514.1 EDN02527.1 - 0.028 12.1 1.3 0.037 11.7 0.9 1.1 1 0 0 1 1 1 0 AAA domain GCOM2 PF15328.1 EDN02528.1 - 0.004 16.9 2.9 0.0049 16.6 2.0 1.2 1 0 0 1 1 1 1 Putative GRINL1B complex locus protein 2 Nucleoplasmin PF03066.10 EDN02528.1 - 0.12 11.8 5.4 0.22 11.0 3.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF3682 PF12446.3 EDN02528.1 - 1.3 9.3 9.7 0.25 11.6 4.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) PBP1_TM PF14812.1 EDN02528.1 - 7.9 6.8 11.6 2.9 8.2 3.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3431 PF11913.3 EDN02531.1 - 5.4e-85 284.3 0.0 7.3e-85 283.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DMPK_coil PF08826.5 EDN02531.1 - 0.61 10.0 4.4 9.7 6.1 0.3 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like PH PF00169.24 EDN02532.1 - 0.0033 17.6 0.5 0.0072 16.5 0.4 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EDN02532.1 - 0.11 12.8 1.1 0.24 11.6 0.7 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain RmlD_sub_bind PF04321.12 EDN02533.1 - 2.3e-48 164.5 0.0 1.1e-47 162.3 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EDN02533.1 - 2.3e-22 79.5 0.0 3e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EDN02533.1 - 2.8e-13 49.3 0.1 2.2e-10 39.8 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EDN02533.1 - 2.2e-09 36.4 0.0 3e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EDN02533.1 - 1.4e-08 34.0 0.1 2e-07 30.1 0.1 2.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EDN02533.1 - 0.00036 20.5 0.1 0.00051 20.0 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EDN02533.1 - 0.0022 17.9 0.3 0.0062 16.4 0.2 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.20 EDN02534.1 - 2.6e-14 53.4 0.2 6.7e-14 52.1 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EDN02534.1 - 1.5e-06 27.9 0.4 4e-06 26.6 0.1 1.8 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EDN02534.1 - 0.00015 21.5 0.0 0.00051 19.8 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EDN02534.1 - 0.0057 16.7 0.1 0.013 15.5 0.1 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EDN02534.1 - 0.017 14.0 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EDN02534.1 - 0.051 12.5 0.1 0.078 11.9 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkH PF02386.11 EDN02536.1 - 6.4e-114 380.2 11.2 3.3e-113 377.8 4.6 2.0 2 0 0 2 2 2 2 Cation transport protein Toxin_12 PF07740.7 EDN02537.1 - 0.038 14.4 2.6 0.038 14.4 1.8 2.1 2 0 0 2 2 2 0 Ion channel inhibitory toxin Tachystatin_A PF11406.3 EDN02537.1 - 0.063 13.1 5.0 0.11 12.3 3.5 1.5 1 1 0 1 1 1 0 Antimicrobial peptide tachystatin A Conotoxin PF02950.12 EDN02537.1 - 0.082 13.7 0.2 0.096 13.4 0.1 1.2 1 0 0 1 1 1 0 Conotoxin Agouti PF05039.7 EDN02537.1 - 0.086 13.1 0.8 0.09 13.1 0.5 1.1 1 0 0 1 1 1 0 Agouti protein Omega-toxin PF06357.6 EDN02537.1 - 0.26 10.9 7.6 0.42 10.2 5.3 1.4 1 0 0 1 1 1 0 Omega-atracotoxin Toxin_19 PF08088.7 EDN02537.1 - 0.36 10.7 8.2 0.96 9.4 5.7 1.7 1 1 0 1 1 1 0 Conotoxin I-superfamily Toxin_7 PF05980.7 EDN02537.1 - 0.39 10.7 7.0 0.77 9.8 4.9 1.7 1 1 0 1 1 1 0 Toxin 7 Pkinase PF00069.20 EDN02538.1 - 4.3e-15 55.5 0.0 1e-14 54.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02538.1 - 0.00044 19.4 0.0 0.00078 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Dynamin_M PF01031.15 EDN02539.1 - 9.6e-106 352.8 0.0 1.9e-105 351.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EDN02539.1 - 3.9e-47 160.1 0.3 7e-47 159.3 0.2 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EDN02539.1 - 1.4e-27 95.3 5.4 1.4e-27 95.3 3.7 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EDN02539.1 - 2e-06 27.7 0.1 7.7e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDN02539.1 - 0.001 19.5 0.1 0.0031 17.9 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 EDN02539.1 - 0.0077 15.3 0.1 0.38 9.8 0.0 2.4 2 0 0 2 2 2 1 AIG1 family ATP-synt_ab PF00006.20 EDN02540.1 - 4.8e-108 359.6 0.0 7.1e-108 359.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDN02540.1 - 2.7e-14 53.6 0.1 4.8e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDN02540.1 - 3.7e-05 23.8 0.4 8.1e-05 22.7 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain YccJ PF13993.1 EDN02540.1 - 0.037 14.0 0.1 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 YccJ-like protein WD40 PF00400.27 EDN02541.1 - 6.1e-28 95.6 18.1 1.1e-05 25.1 0.1 7.2 8 1 0 8 8 8 5 WD domain, G-beta repeat CLTH PF10607.4 EDN02541.1 - 0.0002 21.0 0.1 0.00036 20.2 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PD40 PF07676.7 EDN02541.1 - 0.00042 19.8 0.1 4.6 7.0 0.0 4.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EDN02541.1 - 0.0092 14.1 0.0 0.017 13.2 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DEAD PF00270.24 EDN02542.1 - 3.5e-40 137.2 0.4 7.1e-40 136.2 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN02542.1 - 3.4e-29 100.5 0.2 6.7e-29 99.5 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EDN02542.1 - 0.0039 16.9 0.1 0.009 15.7 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EDN02542.1 - 0.017 14.6 0.2 0.038 13.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EDN02542.1 - 0.03 14.1 0.1 0.065 13.0 0.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EDN02542.1 - 0.047 13.4 0.1 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 EDN02542.1 - 0.11 12.5 0.7 0.53 10.4 0.5 2.0 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 EDN02542.1 - 0.13 11.3 0.0 0.31 10.1 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) AAA_11 PF13086.1 EDN02542.1 - 0.15 11.6 0.3 0.2 11.1 0.2 1.5 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.3 EDN02543.1 - 6.4e-71 237.9 1.2 8.9e-71 237.4 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EDN02543.1 - 8.4e-14 50.8 0.6 1.8e-13 49.7 0.4 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 EDN02543.1 - 2.3e-08 33.9 1.3 9.3e-07 28.8 0.4 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDN02543.1 - 6.1e-08 32.5 3.3 1.7e-07 31.1 0.3 2.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EDN02543.1 - 0.00063 19.8 0.1 0.013 15.6 0.0 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) SpoIISB_antitox PF14185.1 EDN02543.1 - 0.036 13.8 0.4 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Antitoxin SpoIISB, type II toxin-antitoxin system DUF951 PF06107.6 EDN02543.1 - 0.062 12.8 0.2 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) zf-C2H2_4 PF13894.1 EDN02543.1 - 0.87 10.0 3.4 7 7.2 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN02543.1 - 2.1 8.8 3.9 5.5 7.5 0.5 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNA_ligase_A_M PF01068.16 EDN02544.1 - 2e-16 59.9 0.0 1.6e-09 37.4 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EDN02544.1 - 7.4e-06 25.8 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus TPR_11 PF13414.1 EDN02545.1 - 3.4e-15 55.4 10.2 1.8e-06 27.4 0.1 3.6 4 0 0 4 4 4 3 TPR repeat TPR_8 PF13181.1 EDN02545.1 - 3e-13 48.5 4.3 0.0073 16.0 0.0 4.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EDN02545.1 - 3.2e-13 48.6 8.9 0.0028 17.1 0.0 5.2 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EDN02545.1 - 1.4e-12 47.8 17.7 2.3e-05 24.9 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDN02545.1 - 2.2e-12 45.8 15.5 0.013 15.3 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDN02545.1 - 6.9e-08 32.4 13.8 0.047 14.3 0.0 5.3 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDN02545.1 - 7.3e-08 32.6 7.7 0.2 12.0 0.1 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDN02545.1 - 2.7e-07 30.4 15.6 0.007 16.2 0.0 4.4 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDN02545.1 - 3.9e-07 29.7 2.9 0.74 10.1 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EDN02545.1 - 6.2e-07 29.1 6.5 0.00019 21.2 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDN02545.1 - 5.1e-05 22.7 8.2 0.22 11.3 0.1 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDN02545.1 - 6.1e-05 23.2 18.9 0.23 12.0 0.2 6.5 6 1 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EDN02545.1 - 0.0062 16.6 2.6 0.58 10.3 0.0 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR_3 PF13812.1 EDN02545.1 - 0.029 14.6 0.4 2.9 8.3 0.0 3.5 4 0 0 4 4 3 0 Pentatricopeptide repeat domain TPR_15 PF13429.1 EDN02545.1 - 0.046 12.7 5.2 1.1 8.2 1.6 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDN02545.1 - 0.058 13.3 12.5 3.3 7.7 0.3 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF3856 PF12968.2 EDN02545.1 - 0.14 11.9 1.0 0.82 9.4 0.1 2.5 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) CDC45 PF02724.9 EDN02545.1 - 0.74 7.7 2.6 0.89 7.5 1.8 1.1 1 0 0 1 1 1 0 CDC45-like protein APC8 PF04049.8 EDN02546.1 - 2.3e-54 182.9 0.1 4.7e-54 182.0 0.1 1.5 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 DDE_Tnp_1_7 PF13843.1 EDN02546.1 - 1.3e-28 100.0 1.5 1e-09 37.9 0.1 4.3 2 2 2 4 4 4 4 Transposase IS4 PNP_UDP_1 PF01048.15 EDN02548.1 - 3.1e-09 36.1 0.1 5.3e-05 22.3 0.0 2.3 2 1 0 2 2 2 2 Phosphorylase superfamily polyprenyl_synt PF00348.12 EDN02549.1 - 2.9e-70 236.0 0.0 3.4e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Phospholip_A2_3 PF09056.6 EDN02550.1 - 8.2e-35 119.3 1.1 9.9e-35 119.1 0.7 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Glycogen_syn PF05693.8 EDN02551.1 - 0 1122.6 0.0 0 1122.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EDN02551.1 - 1.1e-06 28.1 0.0 0.002 17.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EDN02551.1 - 1.3e-06 28.6 0.1 2.6e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Vps54 PF07928.7 EDN02552.1 - 3e-47 160.1 0.3 8.3e-47 158.7 0.2 1.8 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 EDN02552.1 - 1.6e-08 33.8 0.9 4.5e-08 32.3 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 EDN02552.1 - 0.006 16.3 0.4 0.02 14.6 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) MCM PF00493.18 EDN02553.1 - 1.4e-142 474.4 0.1 1.8e-142 474.0 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDN02553.1 - 5.1e-19 68.9 0.6 1.3e-18 67.6 0.4 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDN02553.1 - 4.2e-06 26.0 0.0 0.00071 18.7 0.0 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDN02553.1 - 5.4e-05 22.9 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EDN02553.1 - 0.00072 19.1 0.1 0.0026 17.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EDN02553.1 - 0.0088 16.4 0.1 0.028 14.8 0.1 1.9 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EDN02553.1 - 0.028 13.8 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 EDN02553.1 - 0.069 13.3 0.1 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MFS_1 PF07690.11 EDN02554.1 - 1.2e-25 90.0 23.3 1.7e-25 89.5 16.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN02554.1 - 1.3e-08 33.5 10.3 1.8e-08 33.0 7.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EDN02554.1 - 2.1e-08 33.1 11.9 2.1e-08 33.1 8.3 1.9 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EDN02554.1 - 0.044 11.9 7.4 0.065 11.3 5.1 1.3 1 1 0 1 1 1 0 Transmembrane secretion effector ATG22 PF11700.3 EDN02554.1 - 0.26 9.7 13.2 0.26 9.7 5.0 2.1 1 1 0 2 2 2 0 Vacuole effluxer Atg22 like ECH PF00378.15 EDN02555.1 - 4.1e-11 42.4 0.0 5.2e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1464 PF07318.7 EDN02555.1 - 0.11 11.2 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) PfkB PF00294.19 EDN02556.1 - 8e-28 97.4 1.0 1.1e-15 57.5 0.1 3.2 2 1 1 3 3 3 3 pfkB family carbohydrate kinase Tau95 PF09734.4 EDN02558.1 - 1.7e-69 234.5 0.0 2.5e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit DUF4568 PF15132.1 EDN02558.1 - 0.06 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) Mucin PF01456.12 EDN02558.1 - 2.5 7.8 9.6 0.07 12.8 2.1 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein B56 PF01603.15 EDN02560.1 - 2.9e-168 559.7 5.6 3.6e-168 559.4 3.9 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) FAT PF02259.18 EDN02561.1 - 2.3e-74 250.4 10.6 5.1e-74 249.3 7.4 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EDN02561.1 - 2.1e-28 99.4 0.3 1e-27 97.1 0.1 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EDN02561.1 - 1e-09 37.6 0.2 3.1e-09 36.1 0.2 1.9 1 0 0 1 1 1 1 FATC domain DUF572 PF04502.8 EDN02562.1 - 1.1e-73 248.3 17.5 1.4e-73 247.9 12.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.8 EDN02562.1 - 0.0039 16.6 0.3 0.0085 15.5 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Benyvirus_14KDa PF07255.6 EDN02562.1 - 0.018 14.8 0.1 0.035 13.9 0.1 1.4 1 0 0 1 1 1 0 Benyvirus 14KDa protein zinc_ribbon_5 PF13719.1 EDN02562.1 - 0.036 13.6 0.6 10 5.8 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EDN02562.1 - 0.058 13.0 0.9 9.6 5.9 0.0 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zf-FCS PF06467.9 EDN02562.1 - 0.081 12.5 3.8 0.24 11.0 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-ribbon_3 PF13248.1 EDN02562.1 - 0.11 11.7 0.3 0.53 9.5 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EDN02562.1 - 0.18 11.2 2.0 13 5.3 0.2 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit SprT-like PF10263.4 EDN02562.1 - 0.59 9.7 2.6 0.99 9.0 1.5 1.6 1 1 0 1 1 1 0 SprT-like family TF_Zn_Ribbon PF08271.7 EDN02562.1 - 1.6 8.0 6.4 2.8 7.3 1.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding D5_N PF08706.6 EDN02562.1 - 9.1 6.3 11.1 3.6 7.6 5.6 2.0 2 1 0 2 2 2 0 D5 N terminal like TPR_2 PF07719.12 EDN02563.1 - 7.4e-30 100.4 12.0 0.00016 21.3 0.0 10.9 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 EDN02563.1 - 8.2e-30 102.2 19.2 3.4e-11 42.6 0.1 8.4 6 3 1 8 8 8 6 TPR repeat TPR_1 PF00515.23 EDN02563.1 - 2.1e-27 93.5 6.6 0.0015 18.0 0.2 10.1 11 0 0 11 11 11 6 Tetratricopeptide repeat Apc3 PF12895.2 EDN02563.1 - 2e-24 85.5 11.5 5.9e-20 71.1 1.0 5.7 6 0 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EDN02563.1 - 2.8e-17 62.3 26.3 1.2e-09 37.9 0.5 8.9 7 2 2 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 EDN02563.1 - 1.7e-15 56.1 16.8 0.12 13.0 0.2 9.6 7 3 3 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 EDN02563.1 - 1.2e-14 54.3 14.6 3.8e-05 23.9 0.1 7.0 6 2 3 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EDN02563.1 - 1.3e-13 51.2 23.8 0.0036 17.9 0.4 8.8 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 EDN02563.1 - 2.5e-12 45.6 3.7 0.14 12.0 0.0 8.4 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDN02563.1 - 1.6e-10 39.9 14.8 0.11 12.3 0.1 8.5 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDN02563.1 - 2.9e-08 33.2 2.4 0.3 11.3 0.0 7.4 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDN02563.1 - 8.9e-08 32.1 9.7 2.7 8.6 0.1 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 EDN02563.1 - 1.2e-07 31.4 11.8 0.039 14.3 1.4 7.8 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 EDN02563.1 - 8.2e-07 28.7 17.4 0.002 17.9 0.1 6.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_21 PF09976.4 EDN02563.1 - 0.013 15.4 5.2 7.9 6.4 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EDN02563.1 - 0.45 10.3 18.7 6.3 6.7 0.1 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat p450 PF00067.17 EDN02564.1 - 2.7e-71 240.4 0.0 3.2e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short_C2 PF13561.1 EDN02565.1 - 3.2e-34 118.7 0.0 4.4e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN02565.1 - 6.8e-33 113.9 0.1 8.8e-33 113.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN02565.1 - 8.4e-10 38.5 0.2 2.2e-09 37.2 0.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN02565.1 - 6.4e-06 25.7 0.1 1.6e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EDN02565.1 - 0.0051 16.8 0.2 0.011 15.7 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding DFP PF04127.10 EDN02565.1 - 0.1 12.2 0.2 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein DUF1996 PF09362.5 EDN02566.1 - 9.1e-81 270.9 0.0 1.2e-80 270.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Cyclase PF04199.8 EDN02569.1 - 9.8e-05 22.1 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.19 EDN02570.1 - 6.3e-73 245.8 25.4 7.4e-73 245.6 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN02570.1 - 1.4e-16 60.1 49.2 6.9e-14 51.3 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.9 EDN02571.1 - 2.6e-14 53.6 0.0 4.5e-14 52.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN02571.1 - 8.9e-12 45.2 0.1 3.5e-09 36.9 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDN02571.1 - 1.8e-11 44.5 2.7 0.00089 19.3 0.1 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDN02571.1 - 0.0035 16.3 0.1 0.13 11.1 0.1 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) CoA_binding_2 PF13380.1 EDN02571.1 - 0.0055 16.8 0.3 0.027 14.6 0.1 2.2 2 1 0 2 2 2 1 CoA binding domain Lycopene_cycl PF05834.7 EDN02571.1 - 0.065 12.1 0.0 7.9 5.2 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.19 EDN02571.1 - 0.07 12.1 0.2 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase ELO PF01151.13 EDN02572.1 - 1.8e-25 89.7 8.6 2.2e-25 89.4 6.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RDD PF06271.7 EDN02572.1 - 5.1 7.0 9.0 1 9.2 2.0 2.0 2 0 0 2 2 2 0 RDD family COX5A PF02284.11 EDN02573.1 - 2.2e-38 130.5 0.5 2.9e-38 130.1 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Fungal_trans PF04082.13 EDN02574.1 - 2.9e-07 29.6 1.0 8.8e-07 28.0 0.7 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN02574.1 - 1.8e-06 27.7 12.2 3.3e-06 26.8 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EDN02575.1 - 7.7e-33 113.6 35.3 5.7e-32 110.7 21.7 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN02575.1 - 3.2e-08 32.2 4.4 4.9e-08 31.6 3.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_Mycoplasma PF07672.8 EDN02575.1 - 0.002 17.3 6.6 0.002 17.3 4.6 1.7 2 0 0 2 2 2 1 Mycoplasma MFS transporter NKAIN PF05640.9 EDN02575.1 - 0.0055 15.6 0.0 0.013 14.5 0.0 1.6 1 0 0 1 1 1 1 Na,K-Atpase Interacting protein DUF2178 PF09946.4 EDN02575.1 - 0.01 15.5 2.9 0.033 13.9 2.0 1.9 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) DUF3099 PF11298.3 EDN02575.1 - 0.18 11.5 4.2 2.6 7.8 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) GATase_5 PF13507.1 EDN02576.1 - 3.5e-97 324.3 0.0 6.3e-97 323.5 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EDN02576.1 - 7.7e-45 152.6 0.5 8.7e-22 77.7 0.0 2.7 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EDN02576.1 - 1.1e-25 89.6 0.9 9e-25 86.7 0.0 2.7 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain Ribosomal_L7Ae PF01248.21 EDN02576.1 - 0.14 11.6 0.1 0.44 10.0 0.1 1.7 1 1 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Spc97_Spc98 PF04130.8 EDN02577.1 - 9.1e-63 212.3 13.5 9.1e-63 212.3 9.4 1.5 2 0 0 2 2 2 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 EDN02577.1 - 0.02 13.0 0.8 0.089 10.8 0.1 2.0 2 0 0 2 2 2 0 gamma-Tubulin ring complex non-core subunit mod21 Glyco_transf_15 PF01793.11 EDN02578.1 - 1.4e-134 448.2 11.5 1.7e-134 447.9 8.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Peptidase_S8 PF00082.17 EDN02579.1 - 1.3e-39 136.0 0.1 1.9e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Methyltransf_32 PF13679.1 EDN02580.1 - 1.9e-15 56.7 1.8 4.8e-15 55.4 1.3 1.7 1 1 0 1 1 1 1 Methyltransferase domain Syntaxin-6_N PF09177.6 EDN02582.1 - 2.8e-26 91.7 0.8 3.7e-25 88.1 0.0 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EDN02582.1 - 1.6e-12 46.9 8.1 8.2e-12 44.6 2.6 3.1 3 0 0 3 3 3 1 SNARE domain NPV_P10 PF05531.7 EDN02582.1 - 0.099 12.9 3.6 1 9.6 0.1 3.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Myosin_tail_1 PF01576.14 EDN02582.1 - 0.17 9.5 5.0 0.71 7.5 0.8 2.0 2 0 0 2 2 2 0 Myosin tail Baculo_PEP_C PF04513.7 EDN02582.1 - 0.22 11.3 1.6 2.1 8.1 0.1 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2072 PF09845.4 EDN02582.1 - 0.47 10.3 2.2 0.54 10.1 0.0 2.0 2 1 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) FlaC_arch PF05377.6 EDN02582.1 - 0.7 9.8 3.1 10 6.0 0.1 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF3618 PF12277.3 EDN02582.1 - 2 8.4 9.7 1.6 8.8 0.2 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3618) NAP PF00956.13 EDN02583.1 - 1.4e-23 83.3 0.1 1.4e-23 83.3 0.1 2.7 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) NmrA PF05368.8 EDN02584.1 - 4.9e-61 205.9 0.0 7.6e-61 205.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Mucin PF01456.12 EDN02584.1 - 0.12 12.1 14.0 0.21 11.3 9.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein ADH_N PF08240.7 EDN02585.1 - 0.0038 16.9 0.0 0.017 14.8 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain 120_Rick_ant PF12574.3 EDN02585.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen Asparaginase PF00710.15 EDN02586.1 - 1.4e-101 339.4 0.0 2.2e-101 338.8 0.0 1.3 2 0 0 2 2 2 1 Asparaginase MTTB PF06253.6 EDN02586.1 - 0.11 10.2 0.5 0.18 9.5 0.3 1.3 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Fungal_trans_2 PF11951.3 EDN02587.1 - 0.033 12.8 0.2 0.045 12.3 0.1 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain LCCL PF03815.14 EDN02590.1 - 9.2e-15 54.4 0.0 1.5e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Chromo PF00385.19 EDN02591.1 - 0.0021 17.7 0.2 0.0037 16.8 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain ACT_7 PF13840.1 EDN02593.1 - 4.4e-22 77.3 0.1 9.1e-17 60.3 0.0 3.4 3 0 0 3 3 3 3 ACT domain WD40 PF00400.27 EDN02594.1 - 3.6e-30 102.7 17.5 2.9e-07 30.1 0.4 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat E_Pc_C PF06752.7 EDN02594.1 - 0.066 12.7 0.7 0.12 11.8 0.5 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus VID27 PF08553.5 EDN02594.1 - 0.19 9.9 0.1 0.34 9.1 0.1 1.3 1 1 0 1 1 1 0 VID27 cytoplasmic protein Septin PF00735.13 EDN02595.1 - 1.2e-114 382.1 0.2 1.2e-114 382.1 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EDN02595.1 - 2.1e-07 30.9 0.0 4.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDN02595.1 - 4.4e-06 26.2 0.4 7.9e-05 22.1 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EDN02595.1 - 1.8e-05 23.9 0.0 5.1e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EDN02595.1 - 0.0028 18.1 0.0 0.0093 16.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EDN02595.1 - 0.003 17.1 0.1 0.006 16.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDN02595.1 - 0.0039 17.3 0.5 0.013 15.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.11 EDN02595.1 - 0.0045 16.1 0.0 0.0085 15.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 EDN02595.1 - 0.0056 15.5 0.0 0.011 14.5 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 EDN02595.1 - 0.0096 15.4 0.8 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 EDN02595.1 - 0.013 14.7 0.1 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 EDN02595.1 - 0.027 13.8 0.6 0.072 12.4 0.2 1.9 2 1 0 2 2 2 0 Ras family T2SE PF00437.15 EDN02595.1 - 0.029 13.2 0.0 0.073 11.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Dynamin_N PF00350.18 EDN02595.1 - 0.034 13.9 5.8 0.82 9.4 0.0 3.1 2 1 1 3 3 3 0 Dynamin family ABC_tran PF00005.22 EDN02595.1 - 0.039 14.2 0.1 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 EDN02595.1 - 0.042 13.5 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EDN02595.1 - 0.058 13.3 1.2 0.31 10.9 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 EDN02595.1 - 0.073 12.5 0.3 2.9 7.3 0.2 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 EDN02595.1 - 0.076 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Bacillus_HBL PF05791.6 EDN02595.1 - 0.092 12.1 1.1 0.16 11.3 0.3 1.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ATP_bind_1 PF03029.12 EDN02595.1 - 0.14 11.7 0.7 8.8 5.7 0.1 2.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 EDN02595.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 EDN02595.1 - 0.19 10.7 2.5 0.33 9.8 1.7 1.7 1 1 0 1 1 1 0 KAP family P-loop domain ArgK PF03308.11 EDN02595.1 - 0.22 10.2 2.3 0.98 8.1 0.0 2.5 3 0 0 3 3 3 0 ArgK protein APG6 PF04111.7 EDN02595.1 - 3 6.8 8.9 5.6 5.9 6.1 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 WD40 PF00400.27 EDN02596.1 - 9e-51 168.0 31.2 5e-12 45.2 0.3 12.1 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.7 EDN02596.1 - 3.9e-28 97.5 0.0 6.6e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EDN02596.1 - 3.9e-08 33.2 2.8 0.011 15.4 0.5 6.3 7 1 0 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EDN02596.1 - 0.00041 18.6 4.3 0.42 8.6 0.0 4.2 2 1 2 4 4 4 2 Nucleoporin Nup120/160 CoiA PF06054.6 EDN02596.1 - 0.12 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Competence protein CoiA-like family DUF1817 PF08847.6 EDN02596.1 - 0.17 11.4 0.1 0.35 10.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1817) SKIP_SNW PF02731.10 EDN02597.1 - 1.5e-67 225.9 5.6 1.5e-67 225.9 3.9 2.4 2 0 0 2 2 2 1 SKIP/SNW domain FAM60A PF15396.1 EDN02597.1 - 1.9 8.1 12.1 4.3 7.0 8.4 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Gly-zipper_OmpA PF13436.1 EDN02598.1 - 2.2e-05 24.0 12.1 3.5e-05 23.4 8.4 1.3 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain SseC PF04888.7 EDN02598.1 - 0.12 11.6 5.4 0.17 11.1 3.7 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF3395 PF11875.3 EDN02600.1 - 1.4e-18 66.9 0.5 2.3e-18 66.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EDN02600.1 - 2.3e-13 49.6 1.5 4.5e-13 48.7 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 EDN02601.1 - 8.8e-12 44.4 0.1 1.3e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_L4 PF00573.17 EDN02604.1 - 1.7e-41 141.7 0.1 2.3e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EDN02604.1 - 1.2e-28 98.7 0.7 1.2e-28 98.7 0.5 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain IFR3_antag PF14754.1 EDN02604.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Papain-like auto-proteinase RVT_2 PF07727.9 EDN02605.1 - 1e-58 198.2 0.0 1.4e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN02605.1 - 2.8e-11 43.5 0.0 7.3e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Glyco_hydro_61 PF03443.9 EDN02607.1 - 0.00073 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AMP-binding PF00501.23 EDN02608.1 - 8.2e-48 162.8 0.0 1.1e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme UPF0029 PF01205.14 EDN02609.1 - 5.7e-08 32.4 0.0 8.9e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EDN02609.1 - 1.1e-07 31.7 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain Aminotran_1_2 PF00155.16 EDN02610.1 - 4.9e-09 35.6 0.0 5.2e-08 32.2 0.0 2.3 2 1 0 2 2 2 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EDN02610.1 - 0.16 10.4 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase RVT_1 PF00078.22 EDN02611.1 - 1.7e-26 92.9 0.0 3.4e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN02611.1 - 3.5e-20 72.2 0.2 1.8e-19 70.0 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EDN02611.1 - 1.6e-13 50.0 2.5 2.3e-13 49.5 0.7 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EDN02611.1 - 0.00023 21.1 3.0 0.00023 21.1 2.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.5 EDN02611.1 - 0.035 13.5 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger Mtf2_C PF14061.1 EDN02611.1 - 0.05 13.4 0.6 0.17 11.8 0.1 2.0 1 1 1 2 2 2 0 Polycomb-like MTF2 factor 2 2-Hacid_dh_C PF02826.14 EDN02612.1 - 0.091 11.9 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Chromo PF00385.19 EDN02613.1 - 0.00075 19.1 0.1 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pet191_N PF10203.4 EDN02614.1 - 0.01 15.8 1.5 0.016 15.2 1.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 DUF1732 PF08340.6 EDN02614.1 - 0.02 14.6 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) Peptidase_C41 PF05417.6 EDN02614.1 - 0.076 12.5 0.3 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Hepatitis E cysteine protease Pkinase PF00069.20 EDN02615.1 - 4.2e-09 35.9 0.1 7.5e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02615.1 - 0.019 14.0 0.1 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 EDN02615.1 - 0.033 13.8 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family HSDR_N_2 PF13588.1 EDN02616.1 - 0.015 15.1 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Mnd1 PF03962.10 EDN02616.1 - 1.2 8.7 5.9 2 8.0 4.1 1.3 1 0 0 1 1 1 0 Mnd1 family DUF2514 PF10721.4 EDN02616.1 - 2.6 7.7 17.3 5.4 6.6 12.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) AAA PF00004.24 EDN02618.1 - 0.029 14.5 0.1 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SET_assoc PF11767.3 EDN02618.1 - 0.042 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated POX PF07526.6 EDN02618.1 - 0.11 12.6 1.4 0.36 11.0 1.0 1.8 1 0 0 1 1 1 0 Associated with HOX Pkinase PF00069.20 EDN02619.1 - 1.1e-08 34.5 0.0 2.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Adeno_terminal PF02459.10 EDN02620.1 - 0.39 8.8 2.4 0.51 8.4 1.7 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Nucleoplasmin PF03066.10 EDN02620.1 - 0.73 9.3 5.2 0.54 9.7 1.4 2.1 2 0 0 2 2 2 0 Nucleoplasmin Nucleo_P87 PF07267.6 EDN02620.1 - 1.5 7.3 4.9 1.9 7.1 3.1 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 XRN_N PF03159.13 EDN02621.1 - 3.9e-48 163.8 1.0 4.9e-48 163.5 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus DUF830 PF05708.7 EDN02621.1 - 0.11 12.5 0.2 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) DUF2672 PF10878.3 EDN02621.1 - 0.51 10.1 4.1 2.5 7.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2672) WD40 PF00400.27 EDN02622.1 - 1.3e-41 139.0 5.0 4.4e-08 32.7 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EDN02622.1 - 1.7e-29 101.5 1.0 3.6e-29 100.4 0.7 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex GTP_cyclohydroI PF01227.17 EDN02623.1 - 9.2e-73 243.3 0.1 1.3e-72 242.8 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EDN02623.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 QueF-like protein Pkinase PF00069.20 EDN02626.1 - 5.9e-73 245.2 0.0 8.3e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02626.1 - 3.9e-35 121.1 0.0 7.1e-35 120.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN02626.1 - 9.9e-06 24.7 0.8 0.0013 17.7 0.0 2.9 1 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 EDN02626.1 - 6.1e-05 22.1 0.3 0.00013 21.1 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN02626.1 - 0.0019 17.9 0.9 0.28 10.8 0.0 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family NUDIX PF00293.23 EDN02627.1 - 1.1e-16 60.6 0.2 1.8e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EDN02627.1 - 2e-13 50.5 0.0 7.2e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EDN02627.1 - 0.00019 20.8 1.5 0.00035 20.0 1.1 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Pkinase PF00069.20 EDN02628.1 - 2.6e-10 39.9 0.0 2e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF572 PF04502.8 EDN02629.1 - 0.066 12.4 3.9 0.1 11.7 2.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Dynamin_N PF00350.18 EDN02630.1 - 8.9e-22 77.6 0.0 2e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EDN02630.1 - 8e-13 47.8 0.1 1.4e-11 43.6 0.0 2.6 2 1 1 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.18 EDN02630.1 - 3.6e-05 23.6 0.0 0.00021 21.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 EDN02630.1 - 0.0032 17.3 1.3 0.0065 16.3 0.2 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain FeoB_N PF02421.13 EDN02630.1 - 0.052 12.8 0.0 0.89 8.8 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.1 EDN02630.1 - 0.075 13.3 0.6 6.4 7.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF4243 PF14027.1 EDN02631.1 - 1.1e-84 284.7 5.3 9.8e-75 252.0 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF4243) NADH5_C PF06455.6 EDN02631.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus Helicase_C_3 PF13625.1 EDN02632.1 - 7.1e-26 90.4 0.0 3.2e-25 88.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN02632.1 - 6.9e-15 55.3 0.0 1.4e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDN02632.1 - 1.1e-12 47.6 0.0 2.5e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDN02632.1 - 1.6e-12 46.8 0.2 2.7e-12 46.0 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EDN02632.1 - 4.4e-07 29.5 0.0 1.1e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.1 EDN02632.1 - 0.0014 17.4 0.1 0.0023 16.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 MIT PF04212.13 EDN02633.1 - 2 8.3 5.8 10 6.1 0.6 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain PNP_UDP_1 PF01048.15 EDN02634.1 - 2.2e-10 39.9 0.0 8e-10 38.0 0.0 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 EDN02634.1 - 4.7e-07 29.6 0.0 1.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EDN02634.1 - 3.1e-06 27.3 0.0 9e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDN02634.1 - 5.6e-06 26.4 0.1 4e-05 23.6 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EDN02634.1 - 0.028 14.5 0.2 0.36 11.0 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EDN02634.1 - 0.038 12.9 0.0 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AA_permease_N PF08403.5 EDN02634.1 - 0.052 12.8 2.4 0.092 12.0 0.0 2.5 3 0 0 3 3 3 0 Amino acid permease N-terminal KaiC PF06745.8 EDN02634.1 - 0.063 12.3 1.2 0.42 9.6 0.5 2.4 1 1 1 2 2 2 0 KaiC Myb_DNA-bind_6 PF13921.1 EDN02635.1 - 0.0067 16.5 5.1 0.0067 16.5 3.5 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain MRI PF15325.1 EDN02635.1 - 6.1 7.8 13.2 0.16 12.9 2.8 2.8 2 1 1 3 3 3 0 Modulator of retrovirus infection Pkinase PF00069.20 EDN02636.1 - 4.9e-09 35.7 0.0 5.7e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02636.1 - 1.8e-08 33.7 0.0 2.1e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EDN02636.1 - 0.0041 16.4 0.0 0.0056 16.0 0.0 1.1 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Ycf1 PF05758.7 EDN02637.1 - 0.0029 15.3 0.0 0.0035 15.1 0.0 1.0 1 0 0 1 1 1 1 Ycf1 Sporozoite_P67 PF05642.6 EDN02637.1 - 0.15 9.9 1.2 0.17 9.7 0.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TRAP_alpha PF03896.11 EDN02637.1 - 0.15 11.0 2.0 0.19 10.6 1.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 EDN02637.1 - 0.79 8.1 10.0 0.95 7.8 6.9 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 EDN02637.1 - 1.6 7.3 9.9 4.5 5.8 7.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Myc_N PF01056.13 EDN02637.1 - 5.7 6.0 10.1 7.4 5.6 7.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DDE_1 PF03184.14 EDN02638.1 - 3.8e-28 98.1 0.0 7.7e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN02638.1 - 2.2e-05 24.1 0.0 7.4e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN02638.1 - 0.0067 15.9 0.6 0.0067 15.9 0.4 2.2 2 0 0 2 2 2 1 helix-turn-helix, Psq domain TraG_N PF07916.6 EDN02638.1 - 1.1 7.6 3.8 1.6 7.0 2.7 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Borrelia_P83 PF05262.6 EDN02638.1 - 1.9 6.6 20.6 3.2 5.9 14.2 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2229 PF09989.4 EDN02638.1 - 2.6 7.4 5.9 5.7 6.3 4.1 1.5 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF2841 PF11001.3 EDN02640.1 - 1.1e-44 151.3 3.1 1.1e-44 151.3 2.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) MAP65_ASE1 PF03999.7 EDN02644.1 - 0.017 13.7 0.1 0.025 13.2 0.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF2520 PF10728.4 EDN02644.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) DUF3435 PF11917.3 EDN02645.1 - 8.8e-122 406.8 3.3 3.2e-89 299.5 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) RVT_1 PF00078.22 EDN02646.1 - 1.3e-21 76.9 0.1 2.8e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN02646.1 - 1.2e-17 64.1 0.0 3.2e-17 62.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EDN02646.1 - 3.4e-13 49.0 1.0 8e-13 47.8 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EDN02646.1 - 0.00014 21.1 0.1 0.00042 19.6 0.0 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Tudor-knot PF11717.3 EDN02646.1 - 0.0028 17.3 0.4 0.027 14.1 0.0 2.6 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain RVP PF00077.15 EDN02646.1 - 0.027 14.3 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EDN02646.1 - 0.067 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDN02646.1 - 0.14 12.7 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease CTD_bind PF04818.8 EDN02647.1 - 1.6e-05 25.0 0.0 2.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF4066 PF13278.1 EDN02648.1 - 0.0013 18.0 0.5 0.2 10.9 0.3 2.6 2 1 0 2 2 2 2 Putative amidotransferase Ank_2 PF12796.2 EDN02649.1 - 2.1e-27 95.2 1.8 1.2e-09 38.3 0.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Pkinase PF00069.20 EDN02649.1 - 8.8e-24 84.0 0.0 1.8e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02649.1 - 2.5e-16 59.5 0.0 4e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.1 EDN02649.1 - 2.5e-16 59.6 4.7 6e-05 23.4 0.1 7.6 6 2 2 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.25 EDN02649.1 - 1.3e-14 53.1 23.5 0.011 15.4 0.0 9.0 9 0 0 9 9 9 5 Ankyrin repeat Ank_3 PF13606.1 EDN02649.1 - 9.9e-14 50.0 10.0 1.7 9.1 0.1 9.4 9 0 0 9 9 9 2 Ankyrin repeat Ank_5 PF13857.1 EDN02649.1 - 2e-08 34.2 9.6 0.64 10.3 0.1 6.7 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Sel1 PF08238.7 EDN02649.1 - 0.0022 18.5 0.7 0.0022 18.5 0.5 2.3 2 0 0 2 2 2 1 Sel1 repeat Kdo PF06293.9 EDN02649.1 - 0.053 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HeLo PF14479.1 EDN02650.1 - 6.9e-23 81.5 0.9 6.9e-23 81.5 0.6 1.8 2 0 0 2 2 2 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 EDN02650.1 - 0.018 14.1 0.0 0.095 11.7 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EDN02650.1 - 0.046 12.8 0.0 0.098 11.7 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain EMP24_GP25L PF01105.19 EDN02651.1 - 2.6e-44 151.1 0.4 3.8e-44 150.5 0.3 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DEAD PF00270.24 EDN02651.1 - 5.4e-11 42.2 0.0 1.5e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN02651.1 - 0.00062 19.6 0.0 0.0019 18.0 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit USP7_ICP0_bdg PF12436.3 EDN02652.1 - 1.1e-74 250.8 0.0 9.7e-74 247.7 0.0 2.5 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EDN02652.1 - 3.1e-71 239.1 1.0 3.2e-70 235.8 0.1 2.8 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 EDN02652.1 - 2.5e-38 131.7 0.2 4.1e-38 131.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDN02652.1 - 1.7e-18 67.1 0.0 3e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EDN02652.1 - 0.034 14.4 0.0 4 7.7 0.0 3.2 1 1 1 2 2 2 0 MATH domain A_deaminase PF00962.17 EDN02653.1 - 6.7e-37 127.1 0.0 1.2e-36 126.3 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase c-SKI_SMAD_bind PF08782.5 EDN02654.1 - 0.15 12.1 0.1 0.56 10.3 0.2 1.8 2 0 0 2 2 2 0 c-SKI Smad4 binding domain DUF3649 PF12365.3 EDN02654.1 - 0.18 11.3 1.7 0.66 9.5 1.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) BCDHK_Adom3 PF10436.4 EDN02655.1 - 7.1e-47 158.9 0.1 1.7e-45 154.4 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EDN02655.1 - 3.4e-09 36.3 0.0 6.6e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EDN02655.1 - 0.0022 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPC22 PF04573.7 EDN02657.1 - 1.6e-33 115.4 0.0 5.6e-25 87.5 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Peptidase_C48 PF02902.14 EDN02658.1 - 2.3e-31 109.1 0.2 1.3e-30 106.6 0.2 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.13 EDN02659.1 - 2.7e-52 176.6 0.0 3.9e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E GST_N_3 PF13417.1 EDN02661.1 - 1.1e-08 35.1 0.0 2.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDN02661.1 - 7.1e-06 25.9 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EDN02661.1 - 0.0028 17.5 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AMP-binding PF00501.23 EDN02662.1 - 6.1e-18 64.4 0.0 8.1e-18 64.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Peptidase_M19 PF01244.16 EDN02663.1 - 3.9e-95 318.4 0.0 4.7e-95 318.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) POT1 PF02765.12 EDN02664.1 - 7.3e-21 74.6 0.0 1.3e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Lin-8 PF03353.10 EDN02664.1 - 5.3 6.2 22.1 2.1 7.5 9.0 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist FMO-like PF00743.14 EDN02665.1 - 3.5e-47 160.8 0.0 9.7e-24 83.4 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EDN02665.1 - 1.8e-16 60.8 0.1 4.5e-15 56.2 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDN02665.1 - 1.6e-10 41.1 0.0 1e-05 25.5 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN02665.1 - 1.1e-09 38.2 0.3 1.2e-07 31.5 0.5 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EDN02665.1 - 4.8e-09 35.5 0.1 3.8e-06 26.0 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EDN02665.1 - 6e-08 32.6 0.0 1.7e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDN02665.1 - 1.1e-05 24.7 0.1 0.00027 20.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EDN02665.1 - 0.0017 16.8 0.0 0.077 11.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EDN02665.1 - 0.0021 16.9 0.0 0.078 11.8 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDN02665.1 - 0.034 14.5 0.0 0.58 10.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EDN02665.1 - 0.046 12.8 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EDN02665.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HDA2-3 PF11496.3 EDN02666.1 - 5.3e-41 140.3 0.0 7.9e-41 139.7 0.0 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 IF-2B PF01008.12 EDN02667.1 - 3.1e-22 78.8 0.0 4e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Transglut_core PF01841.14 EDN02668.1 - 1.3e-09 38.2 0.0 3.1e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily DHH PF01368.15 EDN02669.1 - 7.3e-07 28.9 0.0 4.6e-06 26.3 0.0 2.3 1 1 0 1 1 1 1 DHH family DHHA2 PF02833.9 EDN02669.1 - 0.0083 16.3 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain PLU-1 PF08429.6 EDN02671.1 - 7.7e-110 366.9 19.8 1.2e-107 359.7 13.0 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EDN02671.1 - 5.6e-44 149.0 0.3 1.4e-43 147.7 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EDN02671.1 - 1.5e-26 92.0 0.1 3.9e-26 90.7 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 EDN02671.1 - 5.6e-18 64.3 30.7 6.6e-10 38.5 4.5 3.7 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.11 EDN02671.1 - 2.2e-16 59.6 11.8 6.4e-16 58.1 8.2 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger C1_1 PF00130.17 EDN02671.1 - 0.81 9.4 20.7 0.54 10.0 0.5 3.7 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) V_ATPase_I PF01496.14 EDN02671.1 - 2.9 5.6 6.3 4.7 4.9 4.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF927 PF06048.6 EDN02673.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) Thymidylate_kin PF02223.12 EDN02674.1 - 6.4e-47 159.3 0.0 8e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 EDN02674.1 - 0.00041 19.6 0.1 0.0015 17.8 0.0 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 EDN02674.1 - 0.00043 20.2 0.0 0.00057 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EDN02674.1 - 0.044 13.4 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 EDN02674.1 - 0.07 13.4 0.0 1.3 9.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain APS_kinase PF01583.15 EDN02674.1 - 0.079 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase TGT PF01702.13 EDN02675.1 - 1.9e-44 151.7 0.0 2.5e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MFS_1 PF07690.11 EDN02676.1 - 7.3e-38 130.1 22.3 9.4e-38 129.8 15.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EDN02676.1 - 0.0081 15.9 0.2 0.0081 15.9 0.2 2.9 3 0 0 3 3 3 1 MFS_1 like family Folate_carrier PF01770.13 EDN02676.1 - 0.015 13.8 0.6 0.042 12.3 0.0 2.0 1 1 0 2 2 2 0 Reduced folate carrier MTHFR PF02219.12 EDN02677.1 - 1.5e-95 319.5 0.0 2.1e-95 319.0 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Abhydrolase_3 PF07859.8 EDN02678.1 - 9e-54 182.2 0.0 1.2e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EDN02678.1 - 6.9e-08 31.6 0.0 2.5e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family FLILHELTA PF10306.4 EDN02679.1 - 6.1e-28 96.6 0.0 8.4e-28 96.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA NDK PF00334.14 EDN02680.1 - 5.5e-55 184.8 0.0 6.3e-55 184.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 EDN02681.1 - 2.2e-148 494.7 2.7 2.8e-148 494.4 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EDN02681.1 - 2.8e-23 81.5 0.1 7.1e-23 80.2 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like PQ-loop PF04193.9 EDN02682.1 - 5.8e-22 77.0 3.9 8e-13 47.7 0.2 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF981 PF06168.6 EDN02682.1 - 0.018 14.8 0.5 0.03 14.1 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF981) DUF4491 PF14898.1 EDN02682.1 - 4.1 7.6 5.9 4.8 7.4 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4491) NMT1 PF09084.6 EDN02683.1 - 0.0037 16.8 0.0 0.015 14.8 0.0 1.9 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 EDN02683.1 - 0.033 13.4 0.0 0.24 10.6 0.0 2.1 1 1 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Tetraspannin PF00335.15 EDN02684.1 - 2.2e-06 27.1 4.3 4.9e-06 25.9 3.0 1.6 1 1 0 1 1 1 1 Tetraspanin family FtsX PF02687.16 EDN02684.1 - 5.7 6.7 13.6 0.45 10.2 4.1 2.4 3 0 0 3 3 3 0 FtsX-like permease family Claudin_2 PF13903.1 EDN02684.1 - 7.5 6.2 8.3 5 6.7 2.9 2.2 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Ribosomal_L1 PF00687.16 EDN02685.1 - 1.8e-34 119.0 0.3 3.2e-34 118.1 0.2 1.5 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family TarH PF02203.10 EDN02685.1 - 0.019 14.8 0.4 0.034 13.9 0.3 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue Agglutinin PF07468.6 EDN02685.1 - 0.031 14.2 0.1 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Agglutinin COG2 PF06148.6 EDN02686.1 - 1.2e-32 112.5 0.6 1.2e-32 112.5 0.4 1.6 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EDN02686.1 - 1.2e-06 28.2 0.3 4.6e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Vps51/Vps67 ING PF12998.2 EDN02686.1 - 0.0037 17.5 4.3 0.46 10.7 0.3 2.5 2 1 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding COG5 PF10392.4 EDN02686.1 - 0.0042 17.0 0.2 0.0042 17.0 0.1 2.1 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.9 EDN02686.1 - 0.039 13.5 0.5 3.1 7.4 0.1 2.3 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain IncA PF04156.9 EDN02686.1 - 0.2 11.2 5.4 0.032 13.8 0.5 1.9 2 0 0 2 2 2 0 IncA protein ParA PF10609.4 EDN02688.1 - 5.5e-28 96.6 2.1 5.5e-28 96.6 1.5 3.0 2 1 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EDN02688.1 - 2.4e-11 43.4 0.0 2.9e-10 39.9 0.0 2.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EDN02688.1 - 5.9e-07 28.8 0.0 1.4e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 EDN02688.1 - 0.00013 21.9 0.0 0.00098 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN02688.1 - 0.0005 19.5 0.1 0.0011 18.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EDN02688.1 - 0.0016 17.5 2.0 0.0019 17.3 0.4 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase YhjQ PF06564.7 EDN02688.1 - 0.0095 15.3 1.9 0.02 14.2 0.1 2.0 2 1 0 2 2 2 1 YhjQ protein SRP54 PF00448.17 EDN02688.1 - 0.015 14.7 0.9 3.4 7.0 0.1 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ArgK PF03308.11 EDN02688.1 - 0.016 13.9 0.5 0.016 13.9 0.3 1.5 2 0 0 2 2 2 0 ArgK protein APS_kinase PF01583.15 EDN02688.1 - 0.043 13.4 0.1 0.071 12.7 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF3598 PF12204.3 EDN02688.1 - 0.071 12.3 0.6 0.42 9.7 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3598) AAA_26 PF13500.1 EDN02688.1 - 0.091 12.3 1.6 0.4 10.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain NADHdeh_related PF10125.4 EDN02688.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase I, subunit N related protein OrfB_Zn_ribbon PF07282.6 EDN02688.1 - 0.21 11.2 1.2 0.46 10.1 0.8 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Neisseria_TspB PF05616.8 EDN02688.1 - 2.3 6.5 8.6 3.2 6.0 6.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein TFIIA PF03153.8 EDN02688.1 - 3.3 7.5 10.3 7.3 6.3 1.5 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TOM13 PF08219.6 EDN02689.1 - 1.8e-33 114.1 0.0 2.3e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.15 EDN02690.1 - 1.4e-28 99.9 0.0 1.4e-28 99.9 0.0 1.7 2 0 0 2 2 2 1 60Kd inner membrane protein HDV_ag PF01517.13 EDN02690.1 - 2.2 7.8 10.3 0.93 9.1 5.5 1.5 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen SAM_decarbox PF01536.11 EDN02691.1 - 2.6e-66 223.5 0.0 3.3e-42 144.3 0.0 2.7 1 1 1 2 2 2 2 Adenosylmethionine decarboxylase DUF1546 PF07571.8 EDN02692.1 - 1.3e-33 114.9 0.0 3.1e-33 113.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EDN02692.1 - 1e-25 89.4 0.1 2.1e-25 88.4 0.1 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EDN02692.1 - 8.4e-06 25.8 0.1 3e-05 24.0 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDN02692.1 - 0.0018 18.2 0.1 0.0064 16.5 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EDN02692.1 - 0.06 13.5 0.1 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Kinetochore component CENP-S TFIID-31kDa PF02291.10 EDN02692.1 - 0.094 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CRAL_TRIO PF00650.15 EDN02693.1 - 2.6e-18 65.9 0.1 4.6e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDN02693.1 - 6.8e-07 29.3 0.0 2e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain AMP-binding PF00501.23 EDN02694.1 - 1.5e-13 49.9 0.3 8.8e-13 47.4 0.2 1.8 1 1 0 1 1 1 1 AMP-binding enzyme IPP-2 PF04979.9 EDN02695.1 - 1.3e-12 48.0 4.3 3.7e-08 33.6 0.6 2.3 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) DUF2064 PF09837.4 EDN02697.1 - 0.057 13.0 0.1 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) CoA_transf_3 PF02515.12 EDN02700.1 - 1e-51 174.9 0.0 1.4e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Reo_sigmaC PF04582.7 EDN02701.1 - 0.0043 16.2 6.1 0.0043 16.2 4.3 4.3 2 1 1 4 4 4 2 Reovirus sigma C capsid protein DUF1192 PF06698.6 EDN02701.1 - 0.011 15.5 2.7 0.011 15.5 1.9 6.9 7 1 0 7 7 7 0 Protein of unknown function (DUF1192) Filament PF00038.16 EDN02701.1 - 0.18 11.2 67.1 0.015 14.7 2.9 5.1 2 1 0 4 4 4 0 Intermediate filament protein APG6 PF04111.7 EDN02701.1 - 0.37 9.7 70.2 0.29 10.1 1.9 4.2 2 1 2 4 4 4 0 Autophagy protein Apg6 adh_short_C2 PF13561.1 EDN02702.1 - 2.7e-29 102.6 0.1 3.2e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN02702.1 - 3.4e-28 98.6 1.5 4.3e-28 98.3 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN02702.1 - 2.9e-14 53.1 0.8 3.8e-14 52.7 0.6 1.1 1 0 0 1 1 1 1 KR domain Glyco_hydro_18 PF00704.23 EDN02703.1 - 2e-09 37.3 0.0 2.3e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PhoD PF09423.5 EDN02704.1 - 7.2e-58 196.2 0.0 9.6e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase SRP54 PF00448.17 EDN02706.1 - 4e-74 248.3 2.1 5.7e-74 247.8 1.4 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EDN02706.1 - 1.1e-13 51.1 0.0 2.1e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EDN02706.1 - 1.7e-09 37.3 1.0 3.5e-09 36.3 0.1 2.0 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EDN02706.1 - 3e-07 30.4 0.3 7.4e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EDN02706.1 - 1e-05 25.2 0.2 2.9e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EDN02706.1 - 2.3e-05 25.2 0.0 5.8e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 EDN02706.1 - 5.5e-05 22.6 0.5 0.0002 20.8 0.4 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EDN02706.1 - 6e-05 21.9 0.3 0.00029 19.6 0.2 2.0 1 1 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 EDN02706.1 - 6.8e-05 22.9 0.3 0.00034 20.6 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_31 PF13614.1 EDN02706.1 - 0.00025 20.9 0.0 0.47 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EDN02706.1 - 0.00039 19.5 0.1 0.00065 18.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.15 EDN02706.1 - 0.00045 19.9 0.0 0.00081 19.0 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 EDN02706.1 - 0.0021 18.2 0.0 0.0051 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 EDN02706.1 - 0.0021 17.6 0.1 0.011 15.2 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.12 EDN02706.1 - 0.0053 16.1 0.1 0.018 14.4 0.0 1.9 2 0 0 2 2 2 1 Thymidylate kinase AAA_18 PF13238.1 EDN02706.1 - 0.0065 16.7 0.1 0.016 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain 6PF2K PF01591.13 EDN02706.1 - 0.0082 15.2 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase TrwB_AAD_bind PF10412.4 EDN02706.1 - 0.01 14.4 0.0 0.03 12.9 0.0 1.7 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SRP_SPB PF02978.14 EDN02706.1 - 0.011 15.9 0.1 0.35 11.1 0.0 2.6 2 0 0 2 2 2 0 Signal peptide binding domain AAA_28 PF13521.1 EDN02706.1 - 0.011 15.6 0.1 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EDN02706.1 - 0.021 14.4 0.3 0.044 13.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EDN02706.1 - 0.027 14.4 0.0 0.14 12.1 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase VirE PF05272.6 EDN02706.1 - 0.038 13.4 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E AAA_25 PF13481.1 EDN02706.1 - 0.047 13.0 0.8 0.095 12.0 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EDN02706.1 - 0.089 12.9 0.2 0.2 11.8 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EDN02706.1 - 0.089 12.2 0.0 0.12 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA-like domain Arf PF00025.16 EDN02706.1 - 0.096 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family ABC_tran PF00005.22 EDN02706.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EDN02706.1 - 0.11 11.9 0.8 0.63 9.5 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 EDN02706.1 - 0.12 12.1 1.5 0.35 10.6 0.3 2.3 2 1 1 3 3 2 0 Part of AAA domain SRPRB PF09439.5 EDN02706.1 - 0.14 11.3 0.6 1.2 8.3 0.4 2.1 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Rrp15p PF07890.7 EDN02707.1 - 1.1e-27 96.6 4.1 1.1e-27 96.6 2.8 2.0 2 0 0 2 2 2 1 Rrp15p Gemini_AL2 PF01440.11 EDN02707.1 - 0.027 14.5 0.7 0.059 13.4 0.5 1.7 1 0 0 1 1 1 0 Geminivirus AL2 protein Fer2 PF00111.22 EDN02708.1 - 1.2e-13 50.5 0.6 1.6e-13 50.2 0.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 EDN02709.1 - 6.2e-09 35.4 0.3 0.79 9.4 0.0 5.7 3 2 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_24 PF13578.1 EDN02711.1 - 5.4e-13 49.6 0.0 8.7e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EDN02711.1 - 3.8e-06 26.0 0.0 1.8e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EDN02711.1 - 0.00028 21.4 0.0 0.0024 18.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN02711.1 - 0.0048 16.5 0.0 0.008 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF2089 PF09862.4 EDN02711.1 - 0.034 13.9 0.0 0.07 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) CmcI PF04989.7 EDN02711.1 - 0.05 12.9 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase ADH_N PF08240.7 EDN02712.1 - 1.8e-27 95.2 1.2 1.8e-27 95.2 0.9 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EDN02712.1 - 2.9e-06 26.8 0.2 2.9e-06 26.8 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated AMP-binding PF00501.23 EDN02714.1 - 0.027 12.8 0.0 0.035 12.5 0.0 1.3 1 0 0 1 1 1 0 AMP-binding enzyme Hid1 PF12722.2 EDN02715.1 - 2e-79 267.3 0.0 2.4e-79 267.1 0.0 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein NPCC PF08058.6 EDN02715.1 - 2.6e-33 114.8 0.2 8.5e-24 84.0 0.0 2.2 1 1 1 2 2 2 2 Nuclear pore complex component Dymeclin PF09742.4 EDN02715.1 - 1.1e-14 53.5 0.0 1.2e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.2 EDN02716.1 - 0.15 9.7 0.0 0.17 9.5 0.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cupin_2 PF07883.6 EDN02718.1 - 3.8e-08 32.7 0.0 5.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EDN02718.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) APH PF01636.18 EDN02719.1 - 2e-10 40.8 0.0 4.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN02719.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 EDN02719.1 - 0.18 10.9 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase PFL PF02901.10 EDN02720.1 - 0.0088 14.5 2.2 0.0093 14.4 1.1 1.3 1 1 0 1 1 1 1 Pyruvate formate lyase KAT11 PF08214.6 EDN02721.1 - 4.8e-104 348.1 0.0 6.2e-104 347.7 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Chorion_2 PF03964.10 EDN02722.1 - 9.2 6.8 6.9 3.2 8.3 2.5 1.9 2 0 0 2 2 2 0 Chorion family 2 Pyr_redox_3 PF13738.1 EDN02723.1 - 1.2e-15 58.1 0.0 2.5e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDN02723.1 - 4.4e-11 41.6 0.0 5.9e-10 37.9 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EDN02723.1 - 7.4e-10 38.2 0.0 1.1e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Hydrolase_3 PF08282.7 EDN02724.1 - 0.0015 18.1 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDN02724.1 - 0.014 15.8 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Glyco_transf_21 PF13506.1 EDN02726.1 - 6.5e-11 41.8 0.0 1.4e-05 24.4 0.0 3.5 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EDN02726.1 - 3.2e-10 40.1 0.0 1.7e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EDN02726.1 - 0.00034 20.3 2.2 0.00034 20.3 1.6 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EDN02726.1 - 0.00061 19.5 0.1 0.0028 17.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 2 Ank_2 PF12796.2 EDN02727.1 - 4.2e-13 49.4 0.1 9.9e-13 48.2 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDN02727.1 - 3.4e-10 39.8 1.2 9.9e-08 31.9 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EDN02727.1 - 4.6e-10 38.7 1.6 1.2e-08 34.2 0.2 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EDN02727.1 - 4.8e-09 36.5 0.5 1.3e-07 31.9 0.1 2.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN02727.1 - 1.3e-08 34.2 1.3 3.5e-05 23.6 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat WW PF00397.21 EDN02728.1 - 2.6e-05 23.9 0.9 6.6e-05 22.6 0.6 1.7 1 0 0 1 1 1 1 WW domain PGP_phosphatase PF09419.5 EDN02729.1 - 0.02 14.2 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase Sensor_TM1 PF13755.1 EDN02729.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain Hydrophobin PF01185.13 EDN02730.1 - 2.1e-15 56.9 11.3 2.8e-15 56.5 7.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin NMO PF03060.10 EDN02731.1 - 4.2e-62 210.2 0.4 6.3e-62 209.6 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EDN02731.1 - 4.5e-11 42.2 0.0 0.00011 21.1 0.3 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EDN02731.1 - 0.0021 16.9 0.6 0.004 16.0 0.4 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EDN02731.1 - 0.061 12.2 0.5 0.12 11.2 0.4 1.6 1 1 0 1 1 1 0 Conserved region in glutamate synthase Sdh_cyt PF01127.17 EDN02732.1 - 2.4e-24 85.4 3.3 3.2e-24 85.0 2.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ribonucleas_3_3 PF14622.1 EDN02733.1 - 9.4e-26 90.2 0.1 1.8e-25 89.3 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EDN02733.1 - 0.00013 22.4 0.0 0.00025 21.4 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease III domain Adap_comp_sub PF00928.16 EDN02734.1 - 3.1e-90 301.8 0.0 4.2e-90 301.3 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EDN02734.1 - 7.1e-08 32.2 0.6 1.2e-07 31.5 0.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EDN02734.1 - 0.079 12.1 0.0 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Amidoligase_2 PF12224.3 EDN02738.1 - 0.028 14.0 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme Peptidase_M18 PF02127.10 EDN02739.1 - 3.3e-136 454.2 0.0 3.8e-136 454.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EDN02739.1 - 0.024 13.4 0.1 2.5 6.7 0.0 2.4 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase NOB1_Zn_bind PF08772.6 EDN02740.1 - 2.2e-31 107.4 3.0 3.7e-31 106.7 2.1 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EDN02740.1 - 0.00065 19.5 10.5 0.0019 18.0 7.3 2.0 1 1 0 1 1 1 1 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 EDN02740.1 - 0.0073 15.8 0.7 0.023 14.1 0.5 1.9 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain LsmAD PF06741.8 EDN02740.1 - 3.7 7.7 5.8 1.8 8.7 1.7 2.2 2 0 0 2 2 2 0 LsmAD domain Nop10p PF04135.7 EDN02741.1 - 1.9e-20 72.3 0.4 2.4e-20 72.0 0.3 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DUF2584 PF10763.4 EDN02741.1 - 0.061 13.1 0.0 0.067 13.0 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2584) tRNA_int_endo PF01974.12 EDN02742.1 - 4e-20 71.3 0.1 1.2e-19 69.8 0.1 1.8 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EDN02742.1 - 1.6e-05 24.3 0.0 3.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Rad9_Rad53_bind PF08605.5 EDN02743.1 - 1.4e-14 53.9 0.0 2.7e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 EDN02743.1 - 5.5e-08 32.8 0.0 1.3e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF2602 PF10782.4 EDN02743.1 - 0.33 10.8 0.2 0.69 9.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2602) Ribosomal_L27 PF01016.14 EDN02744.1 - 3.8e-27 93.8 0.1 3.8e-27 93.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal L27 protein Baculo_VP91_N PF08475.5 EDN02745.1 - 0.15 11.3 0.2 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal Scramblase PF03803.10 EDN02746.1 - 3.7e-54 183.1 0.0 2.7e-29 101.8 0.0 3.1 1 1 0 2 2 2 2 Scramblase DUF533 PF04391.7 EDN02746.1 - 0.13 11.5 2.6 0.25 10.6 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Sporozoite_P67 PF05642.6 EDN02746.1 - 3 5.6 8.8 0.35 8.6 2.0 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen UQ_con PF00179.21 EDN02747.1 - 3e-50 169.3 0.0 3.4e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDN02747.1 - 0.17 11.8 0.5 0.39 10.6 0.4 2.0 1 1 0 1 1 1 0 RWD domain TP6A_N PF04406.9 EDN02748.1 - 4.7e-20 71.0 0.0 1.2e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Prenyltrans_2 PF13249.1 EDN02749.1 - 3.8e-34 117.4 10.5 3.5e-14 53.1 0.3 4.8 3 2 2 5 5 5 5 Prenyltransferase-like Prenyltrans PF00432.16 EDN02749.1 - 6.2e-32 108.8 1.8 2e-09 36.8 0.2 5.3 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EDN02749.1 - 3.2e-28 97.9 0.8 6e-17 61.6 0.2 5.3 4 1 1 5 5 5 4 Prenyltransferase-like Pec_lyase PF09492.5 EDN02749.1 - 2.6e-06 26.8 0.8 0.5 9.4 0.0 4.5 3 1 2 5 5 5 3 Pectic acid lyase SGS PF05002.10 EDN02750.1 - 6.1e-24 83.5 10.5 6.1e-24 83.5 7.3 2.6 2 1 0 2 2 2 1 SGS domain CS PF04969.11 EDN02750.1 - 2.8e-16 59.8 0.0 5.5e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 CS domain CDC27 PF09507.5 EDN02750.1 - 0.004 16.4 15.6 0.004 16.4 10.8 1.5 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 Acetyltransf_1 PF00583.19 EDN02751.1 - 1.8e-07 31.0 0.0 7.4e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN02751.1 - 0.00037 20.6 0.0 0.00057 19.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDN02751.1 - 0.00094 19.2 0.4 0.0044 17.1 0.3 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain tRNA-synt_1e PF01406.14 EDN02752.1 - 2.1e-113 378.4 0.0 2.9e-113 377.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EDN02752.1 - 0.00013 20.8 0.1 0.11 11.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 EDN02752.1 - 0.074 13.3 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 DALR domain GCD14 PF08704.5 EDN02753.1 - 1.6e-60 204.6 0.0 2.4e-59 200.8 0.0 2.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EDN02753.1 - 0.001 19.0 0.0 0.0025 17.8 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain TPR_11 PF13414.1 EDN02754.1 - 1.8e-11 43.5 0.8 7.4e-10 38.3 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EDN02754.1 - 6.1e-07 28.8 0.2 0.22 11.5 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat UBA PF00627.26 EDN02754.1 - 3.2e-06 26.7 0.4 1e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain TPR_12 PF13424.1 EDN02754.1 - 5.1e-06 26.3 0.3 0.00079 19.3 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDN02754.1 - 2.5e-05 23.6 0.1 1.5 8.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN02754.1 - 0.0003 21.3 2.7 0.11 13.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN02754.1 - 0.05 14.2 2.0 7.4 7.5 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Peptidase_S64 PF08192.6 EDN02754.1 - 0.18 10.1 1.9 0.33 9.2 1.3 1.4 1 0 0 1 1 1 0 Peptidase family S64 DUF1688 PF07958.6 EDN02755.1 - 1.7e-180 600.0 0.0 2e-180 599.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF2625 PF10946.3 EDN02755.1 - 0.16 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2625 Gtr1_RagA PF04670.7 EDN02756.1 - 6.8e-49 166.0 0.8 1.1e-26 93.4 0.1 2.2 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EDN02756.1 - 0.0001 22.2 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EDN02756.1 - 0.0012 18.3 0.3 0.0041 16.6 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Arf PF00025.16 EDN02756.1 - 0.0021 17.3 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family ABC_tran PF00005.22 EDN02756.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.8 EDN02756.1 - 0.015 14.2 0.1 0.025 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AIG1 PF04548.11 EDN02756.1 - 0.065 12.3 0.1 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 AIG1 family DUF258 PF03193.11 EDN02756.1 - 0.11 11.6 0.4 0.16 11.1 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 EDN02756.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein G-alpha PF00503.15 EDN02756.1 - 1.1 7.8 2.5 3.8 6.0 0.7 2.0 1 1 1 2 2 2 0 G-protein alpha subunit AA_permease PF00324.16 EDN02757.1 - 3.8e-120 401.4 35.0 4.4e-120 401.2 24.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDN02757.1 - 2e-33 115.6 36.9 2.4e-33 115.3 25.6 1.1 1 0 0 1 1 1 1 Amino acid permease RdRP PF05183.7 EDN02758.1 - 2.2e-109 366.7 0.0 1.3e-65 222.2 0.0 2.1 1 1 1 2 2 2 2 RNA dependent RNA polymerase Abhydrolase_6 PF12697.2 EDN02759.1 - 6.7e-20 71.9 3.6 4.3e-19 69.3 2.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN02759.1 - 3.5e-07 30.0 0.1 4.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN02759.1 - 0.02 14.4 0.1 1 8.8 0.0 2.5 2 1 1 3 3 3 0 alpha/beta hydrolase fold BNR_2 PF13088.1 EDN02760.1 - 1.6e-06 27.6 1.2 0.00014 21.3 0.4 2.8 1 1 2 3 3 3 3 BNR repeat-like domain BNR_3 PF13859.1 EDN02760.1 - 0.0051 15.9 0.2 0.017 14.1 0.1 1.8 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 EDN02760.1 - 0.13 12.1 16.6 2 8.5 1.2 4.5 4 0 0 4 4 4 0 BNR/Asp-box repeat Opi1 PF08618.5 EDN02761.1 - 2.7e-83 280.2 19.0 1.2e-53 182.6 2.7 3.3 1 1 3 4 4 4 3 Transcription factor Opi1 adh_short_C2 PF13561.1 EDN02762.1 - 2.3e-24 86.5 1.1 3.2e-24 86.0 0.7 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN02762.1 - 2.4e-20 73.1 1.2 4e-20 72.4 0.9 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN02762.1 - 2.6e-08 33.7 1.2 5.5e-08 32.6 0.8 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN02762.1 - 0.0022 17.4 0.6 1.1 8.6 0.0 2.3 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EDN02762.1 - 0.024 14.4 1.0 0.056 13.2 0.7 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ProRS-C_1 PF09180.6 EDN02762.1 - 0.025 14.5 0.2 0.18 11.7 0.1 2.1 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal 2-Hacid_dh_C PF02826.14 EDN02762.1 - 0.037 13.1 0.3 0.13 11.3 0.0 2.0 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EDN02762.1 - 0.11 12.1 0.2 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rifin_STEVOR PF02009.11 EDN02763.1 - 2.4 7.6 3.2 3.9 7.0 2.2 1.2 1 0 0 1 1 1 0 Rifin/stevor family Voldacs PF03517.8 EDN02764.1 - 2.7e-36 124.4 1.9 4.1e-36 123.8 1.3 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling CAP_N PF01213.14 EDN02764.1 - 0.023 14.0 2.0 0.04 13.2 1.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EDN02764.1 - 9.6 5.4 11.9 2.5 7.4 6.0 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator Peroxidase_2 PF01328.12 EDN02765.1 - 3.9e-16 58.6 0.0 4.6e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DUF2235 PF09994.4 EDN02766.1 - 1.5e-43 149.1 4.5 2.6e-22 79.5 0.1 2.2 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.10 EDN02767.1 - 5.7e-25 87.6 0.0 1.6e-24 86.2 0.0 1.6 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EDN02767.1 - 2.2e-12 46.2 0.0 6e-12 44.8 0.0 1.8 3 0 0 3 3 3 1 Cytochrome P450 GerE PF00196.14 EDN02767.1 - 0.034 13.4 0.1 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_38 PF13936.1 EDN02767.1 - 0.062 12.8 0.0 0.25 10.9 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain Metallophos PF00149.23 EDN02769.1 - 2.6e-35 121.6 0.5 3.7e-35 121.1 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_S8 PF00082.17 EDN02771.1 - 2.2e-56 191.1 9.5 3.1e-56 190.5 6.6 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EDN02771.1 - 2.4e-18 66.4 1.0 3.5e-18 65.9 0.2 1.7 2 0 0 2 2 2 1 Peptidase inhibitor I9 Beach PF02138.13 EDN02773.1 - 5.3e-46 157.2 0.1 7e-46 156.8 0.1 1.1 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EDN02773.1 - 1.1e-11 44.1 3.8 2.3e-06 27.2 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat CPSF_A PF03178.10 EDN02773.1 - 0.069 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 CPSF A subunit region Transaldolase PF00923.14 EDN02774.1 - 1.5e-94 316.3 0.2 1.7e-94 316.1 0.1 1.0 1 0 0 1 1 1 1 Transaldolase DUF4246 PF14033.1 EDN02775.1 - 3.1e-184 613.2 0.0 5e-184 612.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Sod_Cu PF00080.15 EDN02778.1 - 5.5e-47 159.4 4.9 6.4e-47 159.2 3.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DDE_1 PF03184.14 EDN02779.1 - 4.9e-52 176.2 0.0 3.9e-51 173.2 0.0 2.3 3 0 0 3 3 3 1 DDE superfamily endonuclease CDI PF02234.14 EDN02779.1 - 0.73 9.6 3.3 16 5.4 0.1 3.2 2 1 1 3 3 3 0 Cyclin-dependent kinase inhibitor Fungal_trans PF04082.13 EDN02780.1 - 1.9e-11 43.3 0.1 3.5e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2855 PF11017.3 EDN02781.1 - 4.2e-09 35.9 0.2 1.1e-05 24.7 0.1 2.9 2 1 1 3 3 3 3 Protein of unknown function (DUF2855) SNase PF00565.12 EDN02782.1 - 3.5e-80 265.3 3.6 5.4e-26 90.9 0.0 5.8 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EDN02782.1 - 2.2e-27 95.3 0.0 6.2e-27 93.8 0.0 1.8 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 EDN02782.1 - 0.0057 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF3297 PF11730.3 EDN02782.1 - 0.074 12.7 0.1 0.26 10.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3297) CRAL_TRIO PF00650.15 EDN02783.1 - 1.6e-23 82.9 0.0 2.3e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDN02783.1 - 1.8e-09 37.5 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain AT_hook PF02178.14 EDN02784.1 - 7.9e-05 21.9 49.4 0.079 12.6 0.5 5.7 5 0 0 5 5 5 4 AT hook motif Glycophorin_A PF01102.13 EDN02785.1 - 0.0016 18.1 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 Glycophorin A EphA2_TM PF14575.1 EDN02785.1 - 0.0023 18.2 0.0 0.0062 16.8 0.0 1.8 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 EDN02785.1 - 0.029 13.1 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Protocadherin PF08374.6 EDN02785.1 - 0.09 12.3 0.0 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 Protocadherin SKG6 PF08693.5 EDN02785.1 - 0.89 8.9 9.0 1.7 8.0 6.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF1620 PF07774.8 EDN02786.1 - 8.2e-77 257.3 0.0 1.6e-76 256.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EDN02786.1 - 2.1e-24 86.2 15.2 2.7e-19 69.5 1.3 4.3 2 2 0 4 4 4 3 PQQ-like domain PQQ PF01011.16 EDN02786.1 - 4.3e-12 44.9 5.1 0.0012 18.2 0.1 6.6 7 0 0 7 7 7 4 PQQ enzyme repeat DUF1479 PF07350.7 EDN02787.1 - 3.3e-166 552.9 0.0 3.8e-166 552.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Apolipoprotein PF01442.13 EDN02788.1 - 0.0015 18.0 0.0 0.0027 17.2 0.0 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain AAA_24 PF13479.1 EDN02788.1 - 0.004 16.7 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Apc4 PF12896.2 EDN02788.1 - 0.0087 15.3 0.8 0.024 13.9 0.4 1.7 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 DUF585 PF04522.7 EDN02788.1 - 0.01 15.2 0.6 0.015 14.7 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF585) Baculo_PEP_C PF04513.7 EDN02788.1 - 0.014 15.2 0.0 0.042 13.6 0.0 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lipoprotein_7 PF01540.11 EDN02788.1 - 0.021 13.9 0.2 0.023 13.8 0.2 1.2 1 0 0 1 1 1 0 Adhesin lipoprotein DUF1978 PF09321.5 EDN02788.1 - 0.021 14.2 1.9 0.027 13.9 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) RAM PF15320.1 EDN02788.1 - 0.028 14.6 0.1 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Syntaxin_2 PF14523.1 EDN02788.1 - 0.042 13.8 1.6 0.084 12.9 1.1 1.5 1 0 0 1 1 1 0 Syntaxin-like protein FCD PF07729.7 EDN02788.1 - 0.051 13.8 0.4 0.1 12.8 0.0 1.7 2 0 0 2 2 1 0 FCD domain tRNA-synt_1e PF01406.14 EDN02788.1 - 0.059 12.4 1.4 0.071 12.2 0.9 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain MAGSP PF03082.9 EDN02788.1 - 0.061 12.7 0.1 0.071 12.4 0.1 1.1 1 0 0 1 1 1 0 Male accessory gland secretory protein RICH PF05062.7 EDN02788.1 - 0.089 12.9 0.7 13 5.9 0.0 2.4 2 0 0 2 2 2 0 RICH domain Angiomotin_C PF12240.3 EDN02788.1 - 0.1 12.1 1.7 0.2 11.0 0.6 1.8 1 1 1 2 2 2 0 Angiomotin C terminal Egg_lysin PF01303.12 EDN02788.1 - 0.2 11.6 1.7 0.64 10.0 1.2 1.9 1 1 0 1 1 1 0 Egg lysin (Sperm-lysin) HSCB_C PF07743.8 EDN02788.1 - 0.2 12.1 3.2 0.76 10.2 0.8 2.5 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain FliD_C PF07195.7 EDN02788.1 - 0.3 10.3 3.0 0.58 9.4 0.5 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus OmpH PF03938.9 EDN02788.1 - 0.42 10.5 4.3 0.56 10.1 3.0 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Aa_trans PF01490.13 EDN02789.1 - 1.3e-80 270.8 23.8 2.7e-80 269.8 16.5 1.4 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bax1-I PF01027.15 EDN02790.1 - 8.2e-21 74.5 11.2 8e-17 61.5 4.4 2.0 1 1 1 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 Orbi_NS3 PF01616.11 EDN02790.1 - 0.042 12.8 2.1 1.1 8.1 0.1 2.1 2 0 0 2 2 2 0 Orbivirus NS3 Spore_YhaL PF14147.1 EDN02790.1 - 0.13 11.7 0.1 0.4 10.1 0.1 1.8 1 0 0 1 1 1 0 Sporulation protein YhaL DUF2721 PF11026.3 EDN02790.1 - 3.6 7.2 7.3 0.36 10.4 1.2 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2721) UQ_con PF00179.21 EDN02791.1 - 2.6e-28 98.2 0.0 3.2e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Autophagy_N PF03986.8 EDN02791.1 - 0.045 13.5 3.0 0.075 12.8 2.0 1.3 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Nop14 PF04147.7 EDN02791.1 - 2.2 6.1 14.9 2.6 5.8 10.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EDN02791.1 - 2.4 7.3 15.0 2.9 7.1 10.4 1.2 1 0 0 1 1 1 0 SDA1 DUF2796 PF10986.3 EDN02791.1 - 3.5 7.5 10.0 34 4.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) CDC45 PF02724.9 EDN02791.1 - 4.4 5.2 11.8 5.9 4.8 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EDN02791.1 - 5.8 6.0 12.3 7.7 5.6 8.5 1.3 1 0 0 1 1 1 0 NOA36 protein ABC_tran PF00005.22 EDN02792.1 - 2e-52 177.1 0.0 9.4e-31 106.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDN02792.1 - 2.3e-47 161.7 20.4 1.9e-27 96.4 2.1 4.0 3 1 1 4 4 4 3 ABC transporter transmembrane region AAA_21 PF13304.1 EDN02792.1 - 4.4e-09 36.7 2.9 0.00054 20.0 0.4 3.6 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EDN02792.1 - 2.8e-07 30.1 0.1 0.025 13.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EDN02792.1 - 6.7e-07 29.8 1.6 0.00059 20.2 0.1 3.1 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.14 EDN02792.1 - 2.2e-06 27.0 6.4 0.066 12.4 0.9 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EDN02792.1 - 3.4e-05 23.8 0.8 0.38 10.7 0.2 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EDN02792.1 - 7.9e-05 22.1 0.7 0.34 10.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EDN02792.1 - 0.00038 19.4 0.0 0.026 13.4 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EDN02792.1 - 0.00038 20.3 0.1 0.21 11.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EDN02792.1 - 0.00083 18.5 0.6 0.17 10.9 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.12 EDN02792.1 - 0.00091 19.1 0.9 0.072 12.8 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF258 PF03193.11 EDN02792.1 - 0.00098 18.3 0.7 0.41 9.8 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EDN02792.1 - 0.0016 17.9 0.4 2.6 7.4 0.0 2.9 3 0 0 3 3 3 2 AAA-like domain Miro PF08477.8 EDN02792.1 - 0.002 18.5 0.8 2.5 8.6 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EDN02792.1 - 0.0033 18.2 0.3 4.8 8.0 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EDN02792.1 - 0.0039 17.3 1.0 7.1 6.7 0.1 3.5 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 EDN02792.1 - 0.0063 16.0 0.2 2.2 7.7 0.2 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EDN02792.1 - 0.011 16.1 0.7 3.8 7.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EDN02792.1 - 0.014 15.0 0.2 6.7 6.4 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2721 PF11026.3 EDN02792.1 - 0.016 14.8 0.1 0.016 14.8 0.1 3.7 3 0 0 3 3 2 0 Protein of unknown function (DUF2721) IstB_IS21 PF01695.12 EDN02792.1 - 0.017 14.5 0.1 6 6.2 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.24 EDN02792.1 - 0.14 12.3 1.3 9.9 6.3 0.1 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EDN02792.1 - 0.14 11.0 0.1 0.75 8.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EDN02792.1 - 0.15 11.7 0.1 0.6 9.7 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase Pox_A32 PF04665.7 EDN02792.1 - 0.25 10.5 0.5 11 5.2 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Dynamin_N PF00350.18 EDN02792.1 - 0.26 11.0 3.5 3.7 7.3 0.2 2.8 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 EDN02792.1 - 0.27 10.8 1.8 4.2 7.0 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 EDN02792.1 - 0.33 10.7 2.2 2.5 7.8 0.2 2.8 2 1 0 2 2 2 0 Part of AAA domain ATP-synt_ab PF00006.20 EDN02792.1 - 0.49 9.8 2.4 6.4 6.2 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 EDN02792.1 - 1.3 8.3 3.4 1.5 8.2 0.4 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_12 PF13087.1 EDN02793.1 - 4e-29 101.4 0.0 6.3e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EDN02793.1 - 0.0056 16.2 0.0 0.0085 15.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.1 EDN02793.1 - 0.0091 15.4 0.0 0.027 13.9 0.0 1.6 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain Baculo_8kDa PF06096.6 EDN02793.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae 8.2 KDa protein AAA_11 PF13086.1 EDN02794.1 - 3.1e-14 53.1 0.0 1.4e-13 50.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN02794.1 - 4.2e-10 39.2 0.1 1.3e-09 37.7 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EDN02794.1 - 3.8e-07 29.8 0.1 9.4e-07 28.5 0.0 1.7 3 0 0 3 3 3 1 AAA domain ResIII PF04851.10 EDN02794.1 - 0.0026 17.6 0.0 0.0055 16.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EDN02794.1 - 0.0048 16.1 0.0 0.013 14.7 0.0 1.7 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.24 EDN02794.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF2075 PF09848.4 EDN02794.1 - 0.076 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EDN02794.1 - 0.12 11.7 0.0 0.38 10.1 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 EDN02794.1 - 0.13 13.0 2.0 2.2 9.0 0.6 3.1 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EDN02794.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain WD40 PF00400.27 EDN02795.1 - 1.4e-16 59.6 8.6 0.0097 15.7 0.1 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat PRP38 PF03371.10 EDN02797.1 - 1.9e-67 226.1 0.0 2.3e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 PRP38 family FAD_binding_3 PF01494.14 EDN02798.1 - 8.6e-55 186.2 0.0 1.6e-53 182.0 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EDN02798.1 - 3.1e-25 88.7 0.0 5.7e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 EDN02798.1 - 0.0062 15.4 0.0 0.0096 14.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase PDGLE PF13190.1 EDN02799.1 - 0.044 13.4 0.1 0.13 11.9 0.0 1.9 1 0 0 1 1 1 0 PDGLE domain VSP PF03302.8 EDN02801.1 - 0.00065 18.4 3.2 0.00093 17.9 2.2 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Glycophorin_A PF01102.13 EDN02801.1 - 0.0014 18.4 3.2 0.0021 17.8 2.2 1.3 1 0 0 1 1 1 1 Glycophorin A Podoplanin PF05808.6 EDN02801.1 - 0.0023 17.5 6.9 0.0047 16.5 4.8 1.5 1 0 0 1 1 1 1 Podoplanin Rifin_STEVOR PF02009.11 EDN02801.1 - 0.016 14.8 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family TMEM154 PF15102.1 EDN02801.1 - 0.022 14.4 1.1 0.041 13.6 0.8 1.5 1 1 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.1 EDN02801.1 - 0.06 11.8 0.1 0.079 11.4 0.1 1.2 1 0 0 1 1 1 0 Amnionless Alpha_GJ PF03229.8 EDN02801.1 - 0.11 12.7 6.8 0.2 12.0 4.7 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J MtrF PF09472.5 EDN02801.1 - 0.14 11.4 4.1 0.25 10.6 2.9 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Syndecan PF01034.15 EDN02801.1 - 0.17 11.5 0.1 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Vpu PF00558.14 EDN02801.1 - 0.2 11.2 0.3 0.32 10.5 0.2 1.3 1 0 0 1 1 1 0 Vpu protein DUF2668 PF10873.3 EDN02801.1 - 0.91 9.6 8.7 4.1 7.5 6.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2668) Mid2 PF04478.7 EDN02801.1 - 10 5.5 13.2 93 2.3 9.1 2.1 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor HNH_2 PF13391.1 EDN02803.1 - 5.9e-12 45.1 0.1 1.1e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease GST_C PF00043.20 EDN02804.1 - 1.8e-08 34.2 0.0 3.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDN02804.1 - 4.3e-08 32.9 0.5 9.6e-08 31.8 0.4 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EDN02804.1 - 0.00025 21.1 0.0 0.00067 19.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DDOST_48kD PF03345.9 EDN02807.1 - 1.8e-169 563.7 0.0 2.1e-169 563.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Pet191_N PF10203.4 EDN02808.1 - 6.2e-27 93.4 2.5 7.7e-27 93.1 1.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COBRA PF04833.10 EDN02808.1 - 0.061 13.0 0.4 0.084 12.6 0.3 1.2 1 0 0 1 1 1 0 COBRA-like protein Abhydro_lipase PF04083.11 EDN02809.1 - 3.1e-24 84.0 0.0 7.6e-24 82.8 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EDN02809.1 - 4e-18 65.8 0.3 6.9e-18 65.0 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDN02809.1 - 2.3e-05 24.4 0.0 8.8e-05 22.4 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN02809.1 - 0.00034 20.3 0.0 0.0011 18.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EDN02809.1 - 0.00062 19.2 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EDN02809.1 - 0.045 13.1 0.1 11 5.3 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.15 EDN02809.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase zf-MYND PF01753.13 EDN02810.1 - 2.1e-09 37.1 11.9 3.9e-09 36.2 8.3 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EDN02810.1 - 3.5e-05 23.5 5.5 8.2e-05 22.3 3.8 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Ras PF00071.17 EDN02811.1 - 3.3e-37 127.3 0.1 5.4e-36 123.4 0.1 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EDN02811.1 - 7.4e-10 39.3 0.0 8.4e-09 35.9 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN02811.1 - 0.0029 16.8 0.1 0.0059 15.8 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Gly-zipper_OmpA PF13436.1 EDN02811.1 - 0.018 14.6 0.7 0.031 13.9 0.5 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain GTP_EFTU PF00009.22 EDN02811.1 - 0.059 12.8 0.0 0.61 9.4 0.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Carboxyl_trans PF01039.17 EDN02812.1 - 6.4e-144 479.9 0.0 8.1e-144 479.6 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Acyl-CoA_dh_1 PF00441.19 EDN02813.1 - 1.3e-40 138.9 1.3 2.3e-40 138.1 0.9 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EDN02813.1 - 4.8e-30 104.4 0.0 9.9e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EDN02813.1 - 3.2e-20 71.3 0.2 8e-20 70.0 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EDN02813.1 - 6e-17 62.1 0.5 1.1e-16 61.3 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EDN02813.1 - 0.0039 16.6 0.2 0.024 14.0 0.1 2.1 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal CPSase_L_D2 PF02786.12 EDN02814.1 - 1.3e-73 246.7 0.0 2.5e-73 245.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EDN02814.1 - 4.5e-35 119.8 0.0 1.4e-34 118.2 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EDN02814.1 - 5.5e-34 116.5 0.0 1.4e-33 115.2 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EDN02814.1 - 5.1e-18 65.4 0.0 1.7e-17 63.7 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EDN02814.1 - 9.6e-16 57.1 1.7 3e-15 55.5 1.2 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EDN02814.1 - 2e-13 49.7 0.0 3.5e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EDN02814.1 - 6.8e-10 38.6 0.0 1.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EDN02814.1 - 3.1e-06 26.7 0.1 0.055 13.1 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EDN02814.1 - 0.00098 19.0 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EDN02814.1 - 0.0011 18.4 0.0 0.0045 16.5 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 EDN02814.1 - 0.026 14.8 0.1 0.66 10.3 0.0 2.9 3 0 0 3 3 2 0 HlyD family secretion protein GCV_H PF01597.14 EDN02814.1 - 0.028 14.1 0.2 0.12 12.1 0.1 2.0 2 0 0 2 2 2 0 Glycine cleavage H-protein ATPgrasp_ST PF14397.1 EDN02814.1 - 0.03 13.4 0.0 0.073 12.1 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF1752 PF08550.5 EDN02815.1 - 9.1e-10 37.9 5.1 1.8e-09 36.9 3.6 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) VIT1 PF01988.14 EDN02816.1 - 0.17 11.3 2.2 0.2 11.1 1.5 1.1 1 0 0 1 1 1 0 VIT family DUF3755 PF12579.3 EDN02817.1 - 0.083 12.2 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) MIP-T3 PF10243.4 EDN02818.1 - 1 7.7 32.0 1.4 7.2 22.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 eIF-5a PF01287.15 EDN02819.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Abhydrolase_6 PF12697.2 EDN02822.1 - 1.1e-18 67.9 0.5 6.7e-18 65.3 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN02822.1 - 1.2e-11 44.6 0.0 7e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN02822.1 - 9.5e-07 28.6 0.0 1.2e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EDN02822.1 - 0.0056 16.1 0.0 0.0066 15.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 EDN02822.1 - 0.0074 16.1 0.0 0.022 14.6 0.0 1.8 1 1 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EDN02822.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family SRR1 PF07985.7 EDN02823.1 - 2.2e-19 69.0 0.2 4.7e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 SRR1 Isochorismatase PF00857.15 EDN02824.1 - 3.4e-38 131.2 0.1 3.8e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Glyco_hydro_17 PF00332.13 EDN02825.1 - 2.1e-08 33.5 1.8 9.9e-05 21.5 0.2 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF3169 PF11368.3 EDN02825.1 - 0.28 10.3 3.0 0.44 9.7 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Tyrosinase PF00264.15 EDN02827.1 - 2.2e-32 113.0 1.3 2.8e-32 112.6 0.9 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF1031 PF06275.6 EDN02828.1 - 0.049 13.6 0.4 0.09 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Peptidase_C6 PF00851.13 EDN02828.1 - 0.058 12.0 0.0 0.081 11.5 0.0 1.1 1 0 0 1 1 1 0 Helper component proteinase Kringle PF00051.13 EDN02835.1 - 0.098 12.7 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Kringle domain zf-C3H1 PF10650.4 EDN02836.1 - 5.8e-12 44.8 3.3 9.1e-12 44.2 2.3 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain V_ATPase_I PF01496.14 EDN02836.1 - 4.2 5.1 4.0 7 4.3 2.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myosin_head PF00063.16 EDN02837.1 - 1.8e-246 819.5 0.0 5.7e-246 817.8 0.0 2.0 1 0 0 1 1 1 1 Myosin head (motor domain) Isy1 PF06246.7 EDN02837.1 - 1.2e-82 277.1 0.2 1.2e-82 277.1 0.2 8.0 4 3 1 5 5 5 1 Isy1-like splicing family Myosin_tail_1 PF01576.14 EDN02837.1 - 3.8e-24 84.5 249.5 2.4e-14 52.1 32.3 6.3 3 2 3 6 6 6 6 Myosin tail Myosin_N PF02736.14 EDN02837.1 - 0.00015 21.4 0.0 0.00058 19.4 0.0 2.1 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain Filament PF00038.16 EDN02837.1 - 0.0023 17.4 35.0 0.0023 17.4 24.3 8.4 3 2 4 7 7 7 3 Intermediate filament protein AAA_19 PF13245.1 EDN02837.1 - 0.056 13.1 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain MMR_HSR1 PF01926.18 EDN02838.1 - 1.5e-12 47.4 0.0 3.5e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDN02838.1 - 5.6e-05 22.4 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EDN02838.1 - 0.0006 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MobB PF03205.9 EDN02838.1 - 0.0027 17.4 0.0 0.007 16.0 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 EDN02838.1 - 0.0079 15.0 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 EDN02838.1 - 0.0094 15.7 0.0 0.083 12.7 0.0 2.3 2 1 0 2 2 2 1 Dynamin family Miro PF08477.8 EDN02838.1 - 0.021 15.3 0.0 0.046 14.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein ArgK PF03308.11 EDN02838.1 - 0.025 13.3 0.1 0.04 12.6 0.1 1.3 1 0 0 1 1 1 0 ArgK protein PI3Ka PF00613.15 EDN02840.1 - 7.2e-58 194.8 0.0 1.2e-57 194.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EDN02840.1 - 5.1e-10 39.2 0.0 2e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EDN02840.1 - 0.0021 17.8 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4336 PF14234.1 EDN02842.1 - 2e-16 60.0 0.0 1e-11 44.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) Nse4_C PF08743.5 EDN02843.1 - 2.2e-36 123.7 0.0 8.3e-36 121.8 0.0 2.0 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EDN02843.1 - 2.4e-17 62.4 0.1 1.1e-16 60.3 0.0 2.2 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE MARVEL PF01284.18 EDN02844.1 - 9.7e-16 57.8 6.5 1.2e-15 57.5 4.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2530 PF10745.4 EDN02844.1 - 0.015 15.2 0.3 0.015 15.2 0.2 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) PepSY_TM_2 PF13703.1 EDN02844.1 - 0.15 12.2 0.2 0.15 12.2 0.2 2.8 2 1 1 3 3 3 0 PepSY-associated TM helix UPF0233 PF06781.7 EDN02844.1 - 1.1 8.9 3.9 0.38 10.4 0.5 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) SCAMP PF04144.8 EDN02844.1 - 3.4 7.5 7.4 46 3.8 5.2 2.0 1 1 0 1 1 1 0 SCAMP family Metallophos PF00149.23 EDN02845.1 - 1.3e-12 47.5 0.1 3.2e-12 46.2 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDN02845.1 - 1.4e-08 34.7 0.0 2.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ThiF PF00899.16 EDN02846.1 - 9.1e-36 122.6 0.0 1.7e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 EDN02846.1 - 0.0061 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.11 EDN02846.1 - 0.01 15.2 0.1 0.018 14.5 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EDN02846.1 - 0.057 12.4 0.2 0.095 11.7 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 EDN02846.1 - 0.058 12.2 0.3 0.16 10.8 0.1 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Saccharop_dh PF03435.13 EDN02846.1 - 0.095 11.6 1.1 0.15 10.9 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EDN02846.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EDN02846.1 - 0.15 11.4 0.5 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 EDN02846.1 - 0.15 10.6 0.5 0.65 8.5 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase Abhydrolase_1 PF00561.15 EDN02848.1 - 1.1e-19 70.8 0.2 5.3e-19 68.6 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDN02848.1 - 1.8e-09 37.8 15.2 8.2e-09 35.6 5.8 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 EDN02848.1 - 0.0011 18.4 0.1 0.0031 16.9 0.0 1.7 2 0 0 2 2 2 1 Putative esterase SR-25 PF10500.4 EDN02849.1 - 0.44 9.9 5.4 0.71 9.3 3.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 EDN02850.1 - 1.7e-61 207.6 0.0 2.2e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02850.1 - 3e-33 114.9 0.0 6.6e-33 113.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EDN02850.1 - 2.9e-05 23.9 0.1 0.08 12.6 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EDN02850.1 - 0.0072 15.3 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ATP-synt_C PF00137.16 EDN02851.1 - 4.4e-05 23.3 13.9 0.00096 19.0 2.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ApbE PF02424.10 EDN02851.1 - 0.11 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 ApbE family CNH PF00780.17 EDN02852.1 - 8e-28 97.6 0.0 9e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 CNH domain Septin PF00735.13 EDN02853.1 - 5e-107 357.1 0.1 9.5e-107 356.1 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EDN02853.1 - 7.5e-05 22.6 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDN02853.1 - 0.0014 18.5 5.2 0.25 11.1 0.0 2.9 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EDN02853.1 - 0.0025 17.0 0.3 0.0084 15.3 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EDN02853.1 - 0.0041 16.5 0.0 0.12 11.8 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EDN02853.1 - 0.023 15.1 0.3 0.062 13.7 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 EDN02853.1 - 0.068 13.3 0.7 0.18 11.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EDN02853.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.11 EDN02853.1 - 0.09 11.8 0.0 0.09 11.8 0.0 2.0 2 0 0 2 2 2 0 AIG1 family AAA_17 PF13207.1 EDN02853.1 - 0.15 12.9 4.6 0.34 11.7 0.1 2.9 2 2 0 2 2 2 0 AAA domain FMN_bind PF04205.9 EDN02853.1 - 0.15 12.2 0.4 0.52 10.5 0.0 2.0 2 0 0 2 2 2 0 FMN-binding domain ABC_tran PF00005.22 EDN02853.1 - 0.23 11.7 1.4 1.2 9.4 0.0 2.5 2 1 0 2 2 2 0 ABC transporter WD40 PF00400.27 EDN02854.1 - 1.8e-07 30.7 0.0 0.0027 17.5 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat Clathrin_propel PF01394.15 EDN02854.1 - 0.094 13.0 0.0 0.69 10.3 0.0 2.4 2 0 0 2 2 2 0 Clathrin propeller repeat RRM_1 PF00076.17 EDN02855.1 - 2.5e-20 71.8 0.4 9.3e-19 66.8 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN02855.1 - 1.5e-12 47.3 0.0 3.9e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN02855.1 - 4.2e-07 29.7 0.0 1.2e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelP_N PF04592.9 EDN02855.1 - 6.2 6.1 14.5 9.1 5.5 10.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DLIC PF05783.6 EDN02856.1 - 4.4e-40 137.7 0.3 1e-35 123.3 0.0 3.0 3 0 0 3 3 3 3 Dynein light intermediate chain (DLIC) Myb_CC_LHEQLE PF14379.1 EDN02856.1 - 0.16 11.5 3.8 0.33 10.5 2.6 1.5 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif Peptidase_S9 PF00326.16 EDN02857.1 - 3.6e-53 179.9 0.0 5.6e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDN02857.1 - 6e-10 39.0 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN02857.1 - 7.2e-08 32.5 0.6 1.7e-07 31.3 0.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.7 EDN02857.1 - 1.3e-05 24.7 1.8 0.11 12.1 0.3 3.9 3 1 0 3 3 3 2 WD40-like Beta Propeller Repeat COesterase PF00135.23 EDN02857.1 - 0.027 13.2 0.3 0.039 12.6 0.2 1.1 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_2 PF02230.11 EDN02857.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Y_phosphatase3 PF13350.1 EDN02858.1 - 1.3e-31 110.1 0.0 1.9e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EDN02858.1 - 1.2e-14 54.1 0.0 1.2e-13 50.9 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EDN02858.1 - 0.0051 16.1 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EDN02858.1 - 0.025 13.9 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EDN02858.1 - 0.087 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Methyltransf_26 PF13659.1 EDN02859.1 - 8.5e-06 25.7 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.12 EDN02859.1 - 9.2e-06 24.7 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase DUF2052 PF09747.4 EDN02860.1 - 1.3e-37 129.4 12.2 3.8e-37 127.9 8.4 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Pkinase PF00069.20 EDN02861.1 - 9.3e-52 175.7 0.0 1.5e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02861.1 - 9.6e-26 90.3 0.0 1.7e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN02861.1 - 0.00088 18.3 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like AMP-binding PF00501.23 EDN02863.1 - 1.6e-38 132.2 0.2 2.1e-38 131.8 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN02863.1 - 9.3e-11 42.5 0.3 2.3e-10 41.2 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UBA_4 PF14555.1 EDN02864.1 - 3.5e-13 48.8 0.7 9.6e-13 47.4 0.5 1.8 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.11 EDN02864.1 - 0.076 12.5 0.0 3.1 7.3 0.0 2.9 2 0 0 2 2 2 0 CUE domain ATP-synt_B PF00430.13 EDN02864.1 - 1.6 8.4 6.8 0.68 9.7 1.2 2.5 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) SH3_1 PF00018.23 EDN02866.1 - 5e-09 35.4 0.1 9.6e-09 34.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDN02866.1 - 2.1e-06 27.2 0.0 4.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDN02866.1 - 1.4e-05 24.5 0.0 2.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4191 PF13829.1 EDN02866.1 - 0.029 13.4 1.4 0.042 12.9 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF1129 PF06570.6 EDN02866.1 - 0.21 10.8 3.8 0.31 10.3 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PRA1 PF03208.14 EDN02866.1 - 4.1 6.7 7.1 0.72 9.1 2.1 1.7 2 0 0 2 2 2 0 PRA1 family protein DUF3446 PF11928.3 EDN02867.1 - 0.0034 17.5 9.0 0.59 10.3 4.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3446) Secretin_N_2 PF07655.8 EDN02867.1 - 0.011 16.1 3.7 0.017 15.4 2.5 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Bot1p PF12298.3 EDN02869.1 - 4.1e-57 192.8 1.2 4.1e-57 192.8 0.9 1.8 3 0 0 3 3 3 1 Eukaryotic mitochondrial regulator protein RRM_1 PF00076.17 EDN02870.1 - 2.6e-14 52.5 0.0 8.2e-14 50.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN02870.1 - 1.2e-05 25.1 0.0 4.1e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mem_trans PF03547.13 EDN02871.1 - 0.1 10.9 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 Membrane transport protein Ribosomal_S16 PF00886.14 EDN02872.1 - 5.2e-25 86.9 0.0 7.2e-25 86.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.10 EDN02873.1 - 8e-33 113.4 0.0 1.1e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus PUL PF08324.6 EDN02874.1 - 2.6e-56 190.3 0.2 3.4e-56 190.0 0.2 1.1 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 EDN02874.1 - 4.1e-43 143.7 18.8 2.2e-08 33.6 0.9 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat PFU PF09070.6 EDN02874.1 - 2.1e-42 143.8 0.1 3.7e-42 143.0 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) BBS2_Mid PF14783.1 EDN02874.1 - 0.0035 17.0 0.0 0.34 10.7 0.0 3.2 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 EDN02875.1 - 8e-22 76.2 10.3 0.00014 21.5 0.9 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EDN02875.1 - 0.0023 16.1 0.1 0.74 7.8 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.6 EDN02875.1 - 0.0049 15.5 0.0 0.35 9.4 0.0 2.2 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) RRM_1 PF00076.17 EDN02876.1 - 1.5e-17 62.9 0.0 2.9e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN02876.1 - 4e-13 49.1 0.0 8.6e-12 44.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EDN02876.1 - 4.8e-07 30.1 9.1 4.8e-07 30.1 6.3 3.7 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EDN02876.1 - 0.00027 20.7 0.0 0.00048 19.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CH PF00307.26 EDN02877.1 - 2.5e-33 114.3 0.0 8.9e-20 70.7 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EDN02877.1 - 1.2e-14 54.0 0.1 3.6e-14 52.4 0.1 1.9 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EDN02877.1 - 2.5e-12 46.2 0.9 1.7e-08 33.9 0.0 3.0 3 0 0 3 3 3 2 CAMSAP CH domain Spectrin PF00435.16 EDN02877.1 - 0.00056 20.1 4.9 0.55 10.5 2.6 2.5 2 0 0 2 2 2 2 Spectrin repeat EF-hand_8 PF13833.1 EDN02877.1 - 0.00062 19.3 0.1 0.0029 17.1 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EDN02877.1 - 0.0011 18.7 0.1 0.0096 15.7 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EDN02877.1 - 0.0056 15.8 0.1 0.054 12.8 0.0 2.5 2 0 0 2 2 2 1 EF hand EIAV_Rev PF11129.3 EDN02877.1 - 0.063 13.2 2.0 0.16 11.9 1.4 1.6 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus G-alpha PF00503.15 EDN02878.1 - 3.4e-130 434.2 2.1 4.2e-130 433.9 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EDN02878.1 - 8e-16 57.7 1.3 9.6e-11 41.2 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EDN02878.1 - 0.00037 19.9 0.0 0.0016 17.9 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.7 EDN02878.1 - 0.00085 18.5 2.8 0.044 12.9 0.0 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EDN02878.1 - 0.0013 19.1 0.5 2.5 8.6 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EDN02878.1 - 0.015 14.8 0.1 0.042 13.3 0.1 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EDN02878.1 - 0.024 14.0 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDN02878.1 - 0.024 14.5 0.0 1.2 9.1 0.0 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EDN02878.1 - 0.098 12.9 1.3 0.12 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EDN02878.1 - 0.15 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF3573 PF12097.3 EDN02879.1 - 0.13 10.8 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DDE_1 PF03184.14 EDN02880.1 - 1.5e-36 125.5 0.0 3.3e-36 124.4 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN02880.1 - 0.01 15.6 0.0 0.03 14.1 0.0 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN02880.1 - 0.11 12.0 0.0 0.33 10.5 0.0 1.8 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Nucleoplasmin PF03066.10 EDN02881.1 - 0.13 11.7 9.1 0.25 10.8 6.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 EDN02881.1 - 0.16 11.6 2.5 0.42 10.2 1.7 1.7 1 0 0 1 1 1 0 FAM176 family Ribosomal_60s PF00428.14 EDN02881.1 - 1.6 9.1 10.2 4.4 7.7 7.1 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nup188 PF10487.4 EDN02883.1 - 3.4e-54 184.1 1.3 6.7e-54 183.1 0.9 1.4 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.16 EDN02884.1 - 2.1e-94 315.3 0.0 5.4e-94 313.9 0.0 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EDN02884.1 - 5.4e-51 172.9 0.1 3.4e-49 167.0 0.1 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EDN02884.1 - 1.2e-15 57.5 0.0 3e-15 56.1 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I QRPTase_C PF01729.14 EDN02884.1 - 0.0045 16.5 0.1 0.017 14.6 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain FMN_dh PF01070.13 EDN02884.1 - 0.0077 15.1 0.2 0.082 11.7 0.0 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NanE PF04131.9 EDN02884.1 - 0.012 14.6 0.1 0.38 9.6 0.0 2.5 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 EDN02884.1 - 0.018 14.3 0.2 0.12 11.5 0.0 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein PTCB-BRCT PF12738.2 EDN02885.1 - 0.042 13.7 0.5 0.089 12.6 0.3 1.6 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.21 EDN02885.1 - 0.083 13.0 0.2 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Brix PF04427.13 EDN02886.1 - 3e-46 157.4 0.3 4.1e-46 157.0 0.2 1.2 1 0 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.5 EDN02887.1 - 1.1e-73 245.9 1.7 1.9e-73 245.0 1.2 1.5 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EDN02887.1 - 4.7e-59 199.1 0.0 7.1e-59 198.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EDN02887.1 - 1.8e-57 194.6 1.2 2.7e-57 194.0 0.9 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN02887.1 - 1.4e-14 53.5 0.1 4.2e-14 52.0 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EDN02887.1 - 2e-12 47.0 0.3 5e-11 42.5 0.2 2.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EDN02887.1 - 4.5e-09 36.4 0.0 8.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EDN02887.1 - 2.8e-05 23.7 0.1 0.23 10.9 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EDN02887.1 - 0.00021 20.4 0.8 0.0017 17.4 0.0 2.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EDN02887.1 - 0.00053 19.3 0.0 0.0064 15.8 0.0 2.3 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EDN02887.1 - 0.0008 19.0 0.5 0.0031 17.1 0.0 2.1 2 0 0 2 2 2 1 Helicase PIF1 PF05970.9 EDN02887.1 - 0.0023 16.9 0.1 0.47 9.3 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase DEAD PF00270.24 EDN02887.1 - 0.0057 16.1 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_S13_N PF08069.7 EDN02887.1 - 0.0088 15.8 0.0 0.026 14.3 0.0 1.8 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain KaiC PF06745.8 EDN02887.1 - 0.015 14.4 0.0 0.049 12.7 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.1 EDN02887.1 - 0.033 13.5 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 EDN02887.1 - 0.035 13.5 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 EDN02887.1 - 0.053 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EDN02887.1 - 0.087 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EDN02887.1 - 0.1 11.8 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 EDN02887.1 - 0.17 12.1 0.4 0.53 10.4 0.3 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AhpC-TSA_2 PF13911.1 EDN02888.1 - 0.026 14.4 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme RNase_H PF00075.19 EDN02889.1 - 1.2e-07 32.0 0.0 2.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 RNase H RNase_H PF00075.19 EDN02891.1 - 2e-06 28.1 0.0 3.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 RNase H Pkinase PF00069.20 EDN02894.1 - 5.4e-09 35.5 0.0 1.1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN02894.1 - 0.013 15.2 0.0 0.06 13.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN02894.1 - 0.065 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Pet191_N PF10203.4 EDN02895.1 - 0.014 15.3 1.7 0.023 14.7 1.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cytomega_gL PF01801.11 EDN02895.1 - 0.14 11.6 0.3 11 5.4 0.0 2.0 1 1 1 2 2 2 0 Cytomegalovirus glycoprotein L PI-PLC-Y PF00387.14 EDN02896.1 - 1.4e-08 34.7 0.1 2.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EDN02896.1 - 1.3e-07 31.3 0.0 2.9e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 C2 domain EF-hand_6 PF13405.1 EDN02897.1 - 0.00056 19.5 0.2 1.3 9.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_like PF09279.6 EDN02897.1 - 0.0016 18.3 0.0 0.016 15.2 0.0 2.2 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.27 EDN02897.1 - 0.0032 16.6 0.5 0.092 12.1 0.0 2.7 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 EDN02897.1 - 0.0041 16.7 0.1 0.065 12.8 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 EDN02897.1 - 0.0068 16.5 1.2 0.064 13.3 0.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair DUF2852 PF11014.3 EDN02897.1 - 0.09 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) HNH_2 PF13391.1 EDN02899.1 - 5.6e-17 61.2 0.2 1.2e-16 60.2 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease FMN_dh PF01070.13 EDN02900.1 - 4.8e-23 81.5 0.6 1.8e-19 69.8 0.1 2.0 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Oxidored_molyb PF00174.14 EDN02901.1 - 2e-49 167.2 0.0 2.8e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EDN02901.1 - 3e-09 36.6 0.2 6.8e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Sec5 PF15469.1 EDN02902.1 - 5.3e-32 111.0 0.0 9.9e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 EDN02902.1 - 1.1e-05 25.1 0.6 3.1e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Vps51/Vps67 Eaf7 PF07904.8 EDN02903.1 - 0.0087 16.0 0.2 1.2 9.1 0.0 2.6 1 1 1 2 2 2 1 Chromatin modification-related protein EAF7 Prothymosin PF03247.9 EDN02903.1 - 0.021 14.9 11.4 0.037 14.1 7.9 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF573 PF04504.9 EDN02903.1 - 0.034 14.4 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF573 NOA36 PF06524.7 EDN02903.1 - 0.34 10.1 4.8 0.46 9.6 3.3 1.1 1 0 0 1 1 1 0 NOA36 protein S-antigen PF05756.6 EDN02903.1 - 0.61 10.1 4.6 1.1 9.2 3.2 1.4 1 0 0 1 1 1 0 S-antigen protein Vfa1 PF08432.5 EDN02903.1 - 2.2 8.2 6.5 3.2 7.7 4.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Myc_N PF01056.13 EDN02903.1 - 7.9 5.5 8.3 1.6 7.8 3.2 1.7 2 0 0 2 2 2 0 Myc amino-terminal region Spc97_Spc98 PF04130.8 EDN02904.1 - 1.1e-55 189.0 0.5 1.1e-55 189.0 0.3 1.3 2 0 0 2 2 2 1 Spc97 / Spc98 family Pox_A_type_inc PF04508.7 EDN02904.1 - 0.061 13.1 0.5 0.28 11.0 0.3 2.2 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat rRNA_processing PF08524.6 EDN02905.1 - 0.00044 20.0 0.5 0.00044 20.0 0.4 2.2 2 0 0 2 2 2 1 rRNA processing Phlebovirus_NSM PF07246.6 EDN02905.1 - 0.46 9.6 7.3 0.16 11.0 2.3 1.8 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M Hepatitis_core PF00906.15 EDN02905.1 - 3.9 7.0 9.5 5.9 6.4 6.6 1.2 1 0 0 1 1 1 0 Hepatitis core antigen Chromosome_seg PF13889.1 EDN02906.1 - 3.8e-22 77.9 0.3 8.6e-22 76.7 0.2 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.1 EDN02906.1 - 4.8e-14 52.4 0.0 1.2e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) CAP_N PF01213.14 EDN02907.1 - 3.8e-64 216.9 14.8 1e-31 110.3 0.0 3.3 2 1 1 3 3 3 3 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EDN02907.1 - 1.1e-54 184.0 1.8 1.5e-54 183.6 1.3 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EDN02907.1 - 0.17 11.2 4.8 1.2 8.5 1.7 2.2 1 1 0 2 2 2 0 Tubulin binding cofactor C PfkB PF00294.19 EDN02908.1 - 8.6e-16 57.9 0.0 1.5e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribonucleas_3_3 PF14622.1 EDN02910.1 - 4.9e-07 29.7 0.0 0.00098 19.0 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EDN02910.1 - 6.9e-06 26.4 0.0 1.3e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 EDN02910.1 - 0.0002 21.9 0.0 0.00038 20.9 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif BSP PF04450.7 EDN02911.1 - 4.1e-36 124.3 0.0 6.2e-28 97.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase of plants and bacteria CLASP_N PF12348.3 EDN02912.1 - 8.8e-150 496.3 0.1 1.2e-85 286.5 0.0 2.6 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 EDN02912.1 - 3.7e-09 35.8 0.2 0.015 15.3 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EDN02912.1 - 2.6e-07 30.8 1.0 0.046 14.0 0.0 4.2 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EDN02912.1 - 0.00059 20.2 0.1 1.1 9.8 0.0 3.5 2 0 0 2 2 2 2 HEAT-like repeat Cnd1 PF12717.2 EDN02912.1 - 0.0023 17.8 0.0 0.019 14.7 0.0 2.6 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EDN02912.1 - 0.072 12.9 0.0 41 4.2 0.0 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RhoGAP PF00620.22 EDN02913.1 - 8.1e-46 155.3 0.0 1.9e-45 154.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EDN02913.1 - 1.4e-14 53.8 18.4 9.7e-10 38.3 1.5 2.4 2 0 0 2 2 2 2 LIM domain DUF3078 PF11276.3 EDN02913.1 - 0.079 13.1 0.9 0.48 10.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3078) CmcI PF04989.7 EDN02913.1 - 0.089 12.0 0.3 0.17 11.1 0.2 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase OrfB_Zn_ribbon PF07282.6 EDN02913.1 - 2.9 7.6 14.7 0.31 10.7 0.3 3.5 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 EDN02913.1 - 4.1 7.4 21.4 0.66 9.9 1.0 4.3 4 0 0 4 4 4 0 Zinc ribbon domain Thiolase_N PF00108.18 EDN02916.1 - 1.4e-70 237.3 0.0 2.1e-70 236.7 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDN02916.1 - 1.1e-41 141.0 0.9 2.2e-41 140.1 0.1 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EDN02916.1 - 0.0049 16.5 0.0 0.49 10.0 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 EDN02916.1 - 0.053 13.5 0.0 0.36 10.8 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AA_permease PF00324.16 EDN02918.1 - 4.2e-49 167.1 20.7 3.6e-45 154.2 9.1 2.8 2 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EDN02918.1 - 4.3e-18 65.0 18.6 2.1e-17 62.7 12.9 2.1 1 1 0 1 1 1 1 Amino acid permease DUF2207 PF09972.4 EDN02918.1 - 1.3 7.5 4.0 2.2 6.7 0.1 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) HSP70 PF00012.15 EDN02919.1 - 4.6e-166 553.2 1.2 6.1e-166 552.8 0.0 1.7 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EDN02919.1 - 1.7e-10 40.0 0.0 4.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 EDN02919.1 - 0.00074 19.3 1.7 1.1 9.1 0.1 3.4 2 2 0 2 2 2 2 Cell division protein FtsA Trans_reg_C PF00486.23 EDN02919.1 - 0.13 12.2 0.0 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal V_ATPase_I PF01496.14 EDN02919.1 - 0.15 9.8 4.9 0.24 9.1 3.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Chitin_synth_2 PF03142.10 EDN02920.1 - 5e-17 61.4 0.6 6.9e-17 61.0 0.4 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EDN02920.1 - 0.00017 21.3 11.0 0.00046 19.9 7.6 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDN02920.1 - 0.096 12.4 0.1 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 TRP PF06011.7 EDN02921.1 - 1.2 7.5 6.2 1.6 7.2 4.3 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel La PF05383.12 EDN02922.1 - 2e-16 59.4 0.1 3.2e-16 58.8 0.1 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EDN02922.1 - 1.2e-05 24.8 0.1 2.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN02922.1 - 1.6e-05 24.7 0.0 5e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN02922.1 - 0.07 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DAO PF01266.19 EDN02923.1 - 2.9e-34 118.5 0.0 3.5e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase MFS_1 PF07690.11 EDN02924.1 - 5e-22 78.0 37.0 5e-22 78.0 25.6 2.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN02924.1 - 3.8e-06 25.3 9.3 6.1e-06 24.7 6.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EDN02924.1 - 0.0035 15.5 5.6 0.052 11.6 1.5 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector Zn_clus PF00172.13 EDN02925.1 - 3.4e-10 39.6 12.4 4.8e-10 39.1 8.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.5 EDN02925.1 - 0.032 14.2 0.4 2 8.4 0.0 2.2 2 0 0 2 2 2 0 HalX domain DUF1192 PF06698.6 EDN02925.1 - 0.35 10.7 1.5 0.42 10.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) bZIP_1 PF00170.16 EDN02925.1 - 7.3 6.6 7.5 5.9 6.9 0.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor Rox3 PF08633.5 EDN02927.1 - 3.9e-33 115.3 0.0 6.8e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Rox3 mediator complex subunit HAD_2 PF13419.1 EDN02928.1 - 2.2e-25 89.8 0.0 3.1e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN02928.1 - 0.0011 18.5 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Thr_synth_N PF14821.1 EDN02929.1 - 2.9e-29 100.8 0.0 6.3e-29 99.8 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EDN02929.1 - 1.1e-14 54.3 0.0 3.1e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4202 PF13875.1 EDN02930.1 - 4.1e-69 231.9 0.8 4.6e-69 231.7 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) RuvA_C PF07499.8 EDN02930.1 - 0.13 12.4 0.2 18 5.6 0.0 2.7 3 0 0 3 3 3 0 RuvA, C-terminal domain VIT1 PF01988.14 EDN02931.1 - 2.4e-49 167.7 6.0 2.7e-49 167.5 4.2 1.0 1 0 0 1 1 1 1 VIT family Abhydrolase_9_N PF15420.1 EDN02931.1 - 0.028 14.1 1.2 0.062 13.0 0.9 1.5 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus MadL PF03817.8 EDN02931.1 - 2.4 8.0 9.1 0.11 12.2 2.1 1.9 2 1 0 2 2 2 0 Malonate transporter MadL subunit VPS9 PF02204.13 EDN02933.1 - 1.5e-28 98.8 0.0 2.7e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EDN02933.1 - 7.6e-10 38.0 0.1 4.5e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 CUE domain Asn_synthase PF00733.16 EDN02934.1 - 3e-52 177.6 0.0 4.4e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EDN02934.1 - 3.5e-06 26.7 0.0 9.8e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EDN02934.1 - 0.018 14.2 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein GATase_6 PF13522.1 EDN02934.1 - 0.095 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain zf-RING_2 PF13639.1 EDN02935.1 - 1.1e-13 50.7 10.2 1.7e-13 50.1 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDN02935.1 - 8.9e-08 32.1 5.1 1.8e-07 31.1 3.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDN02935.1 - 8.7e-07 28.5 7.4 1.4e-06 27.8 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN02935.1 - 3.3e-05 23.5 7.4 5.1e-05 22.9 5.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDN02935.1 - 3.8e-05 23.6 9.0 6e-05 22.9 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN02935.1 - 7.2e-05 22.3 5.4 0.00011 21.7 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDN02935.1 - 0.0055 16.5 5.0 0.014 15.2 3.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EDN02935.1 - 0.26 10.9 9.7 0.43 10.1 6.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EDN02935.1 - 0.41 10.6 5.9 1.2 9.1 4.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 EDN02935.1 - 0.43 10.3 9.7 1.5 8.5 6.7 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 EDN02935.1 - 1.6 8.4 9.1 2.7 7.7 6.3 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 EDN02935.1 - 1.9 8.6 9.0 3.5 7.7 6.3 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EDN02935.1 - 3.9 7.4 8.4 8.5 6.3 5.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3844 PF12955.2 EDN02936.1 - 3.1e-40 136.4 2.9 4.9e-40 135.8 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 EDN02936.1 - 0.041 14.0 6.9 0.18 11.9 4.8 2.1 1 1 0 1 1 1 0 EGF-like domain Thioredoxin_4 PF13462.1 EDN02939.1 - 8.6e-09 35.6 0.0 1.2e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EDN02939.1 - 0.15 11.6 1.5 0.8 9.2 1.0 2.3 1 1 0 1 1 1 0 DSBA-like thioredoxin domain CKS PF01111.14 EDN02940.1 - 9.5e-36 121.4 1.1 1.2e-35 121.0 0.2 1.5 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 EDN02940.1 - 8.1 6.6 14.4 3.7 7.7 0.3 4.2 4 0 0 4 4 4 0 APC 15 residue motif Bromodomain PF00439.20 EDN02941.1 - 1.7e-21 75.9 0.7 1.9e-14 53.3 0.0 2.7 3 0 0 3 3 3 2 Bromodomain SpoVG PF04026.7 EDN02941.1 - 0.024 14.6 0.1 2.7 8.0 0.0 2.7 2 1 0 2 2 2 0 SpoVG HSP70 PF00012.15 EDN02942.1 - 4.3e-230 764.7 5.7 4.8e-230 764.5 4.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDN02942.1 - 1.5e-15 56.6 0.0 1.4e-14 53.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EDN02942.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain MRC1 PF09444.5 EDN02942.1 - 0.44 10.8 5.4 0.11 12.8 1.1 1.9 2 0 0 2 2 2 0 MRC1-like domain Metallophos PF00149.23 EDN02943.1 - 1.2e-11 44.4 0.0 1.5e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 EDN02945.1 - 1.5e-11 43.6 0.1 2.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Trm112p PF03966.11 EDN02947.1 - 2.3e-16 59.9 0.0 2.8e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 EDN02947.1 - 0.046 13.9 0.1 0.085 13.1 0.1 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF1451 PF07295.6 EDN02947.1 - 0.065 13.0 0.5 0.09 12.5 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1451) DUF59 PF01883.14 EDN02948.1 - 5e-06 26.4 0.1 1e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 GTP_EFTU PF00009.22 EDN02949.1 - 3.1e-42 144.1 0.0 4.7e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EDN02949.1 - 6e-19 67.7 0.0 1.6e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDN02949.1 - 1.2e-07 31.7 0.0 2.8e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EDN02949.1 - 2.2e-07 30.6 0.2 2.7e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EDN02949.1 - 0.00034 20.5 0.0 0.00067 19.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDN02949.1 - 0.00088 19.7 0.0 0.0021 18.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein SCAN PF02023.12 EDN02949.1 - 0.038 13.4 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 SCAN domain Thiolase_C PF02803.13 EDN02950.1 - 2.4e-36 123.8 3.6 2.8e-36 123.6 2.5 1.0 1 0 0 1 1 1 1 Thiolase, C-terminal domain Fungal_trans_2 PF11951.3 EDN02951.1 - 1.9e-08 33.3 0.2 3.2e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zip PF02535.17 EDN02952.1 - 1.1e-30 106.7 2.3 1.7e-30 106.1 1.6 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2401 PF10287.4 EDN02953.1 - 1.3e-87 293.2 0.0 1.5e-87 293.0 0.0 1.0 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) Atg14 PF10186.4 EDN02954.1 - 9.1e-86 287.5 0.3 1.2e-85 287.0 0.2 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 EDN02954.1 - 0.087 12.5 1.7 0.19 11.4 1.2 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Baculo_p24 PF05073.7 EDN02954.1 - 0.11 12.0 1.1 0.23 11.0 0.7 1.5 1 0 0 1 1 1 0 Baculovirus P24 capsid protein FlgN PF05130.7 EDN02954.1 - 0.17 12.1 1.8 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 FlgN protein Rabaptin PF03528.10 EDN02954.1 - 3.7 7.5 7.6 0.16 11.9 0.4 2.2 2 1 1 3 3 3 0 Rabaptin DUF4654 PF15547.1 EDN02956.1 - 7.8 6.8 8.3 1.5 9.0 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4654) LMBR1 PF04791.11 EDN02957.1 - 4.5e-18 65.0 3.6 4.5e-18 65.0 2.5 2.2 1 1 1 2 2 2 2 LMBR1-like membrane protein CPSF_A PF03178.10 EDN02958.1 - 1.2e-103 346.5 0.0 1.3e-102 343.1 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EDN02958.1 - 0.014 13.6 0.0 0.059 11.4 0.0 2.0 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term AAA PF00004.24 EDN02960.1 - 3.4e-49 166.4 0.0 6.3e-42 142.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EDN02960.1 - 2.9e-07 30.0 0.0 7.4e-06 25.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 EDN02960.1 - 1.7e-06 28.1 0.0 2.3e-05 24.4 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain Bromodomain PF00439.20 EDN02960.1 - 3.7e-06 26.7 0.0 1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Bromodomain AAA_2 PF07724.9 EDN02960.1 - 1.1e-05 25.4 0.0 3.2e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EDN02960.1 - 6.6e-05 22.6 0.0 0.0009 18.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 EDN02960.1 - 6.9e-05 22.9 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.1 EDN02960.1 - 0.0001 22.4 0.6 0.0023 18.0 0.0 3.0 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EDN02960.1 - 0.0013 18.2 0.0 0.004 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EDN02960.1 - 0.0013 18.9 0.0 0.0037 17.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 EDN02960.1 - 0.002 18.0 0.0 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDN02960.1 - 0.008 15.9 8.9 0.025 14.3 0.0 3.7 4 0 0 4 4 3 1 Part of AAA domain AAA_33 PF13671.1 EDN02960.1 - 0.0086 15.9 1.0 0.029 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EDN02960.1 - 0.01 14.5 0.0 0.018 13.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 EDN02960.1 - 0.017 14.3 0.1 0.076 12.1 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EDN02960.1 - 0.017 15.9 0.0 0.017 15.9 0.0 3.8 4 0 0 4 4 3 0 AAA domain RuvB_N PF05496.7 EDN02960.1 - 0.044 12.8 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EDN02960.1 - 0.058 13.0 0.0 0.16 11.6 0.0 1.8 1 1 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EDN02960.1 - 0.059 12.8 0.0 2.1 7.7 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_3 PF07726.6 EDN02960.1 - 0.081 12.5 0.0 0.25 10.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EDN02960.1 - 0.091 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EDN02960.1 - 0.14 10.9 0.0 0.4 9.4 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 EDN02960.1 - 0.45 10.3 0.1 1.4 8.8 0.0 1.7 2 0 0 2 2 1 0 Torsin Sec66 PF09802.4 EDN02961.1 - 1.3e-83 279.0 0.1 1.6e-83 278.7 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Duffy_binding PF05424.6 EDN02961.1 - 0.027 14.2 1.3 0.091 12.5 0.9 1.8 1 1 0 1 1 1 0 Duffy binding domain PPR_2 PF13041.1 EDN02962.1 - 1.6e-11 43.9 0.1 0.017 15.0 0.0 5.5 5 1 1 6 6 6 2 PPR repeat family PPR_3 PF13812.1 EDN02962.1 - 1.8e-08 33.9 1.5 0.3 11.4 0.0 6.3 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 EDN02962.1 - 0.00057 19.6 2.3 0.046 13.7 0.0 4.1 4 0 0 4 4 4 1 PPR repeat PPR_1 PF12854.2 EDN02962.1 - 0.067 12.6 1.2 0.54 9.7 0.5 2.7 3 0 0 3 3 3 0 PPR repeat Metal_resist PF13801.1 EDN02962.1 - 0.09 12.7 0.4 0.37 10.7 0.3 2.2 1 0 0 1 1 1 0 Heavy-metal resistance ORC3_N PF07034.6 EDN02963.1 - 3.4e-32 111.7 0.0 2.6e-31 108.8 0.0 1.9 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Nop14 PF04147.7 EDN02965.1 - 1.6e-288 959.2 27.9 1.9e-288 959.0 19.3 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.8 EDN02965.1 - 0.051 12.4 0.1 0.13 11.0 0.1 1.6 1 0 0 1 1 1 0 Noc2p family COesterase PF00135.23 EDN02966.1 - 9.6e-94 314.9 0.2 1.1e-93 314.7 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EDN02966.1 - 8.2e-08 32.0 0.0 1.7e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDN02966.1 - 0.00029 20.1 0.0 0.00049 19.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Cupin_8 PF13621.1 EDN02968.1 - 1.5e-43 149.1 0.0 2.3e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 EDN02968.1 - 2.6e-19 69.5 0.0 3.7e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Cupin_4 PF08007.7 EDN02968.1 - 1.2e-05 24.7 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_4 PF13418.1 EDN02968.1 - 0.0022 17.7 19.6 0.0034 17.1 0.2 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EDN02968.1 - 0.0029 17.5 8.9 0.51 10.3 1.0 3.5 3 0 0 3 3 3 2 Kelch motif WD40 PF00400.27 EDN02969.1 - 2.4e-06 27.2 1.2 0.0003 20.5 0.0 3.9 5 0 0 5 5 5 1 WD domain, G-beta repeat CNH PF00780.17 EDN02969.1 - 0.0099 15.3 0.0 3 7.1 0.0 2.3 2 0 0 2 2 2 2 CNH domain Hira PF07569.6 EDN02969.1 - 0.027 13.6 0.0 0.085 12.0 0.0 1.8 2 0 0 2 2 2 0 TUP1-like enhancer of split Coatomer_WDAD PF04053.9 EDN02969.1 - 0.11 11.2 0.0 0.33 9.6 0.0 1.8 3 0 0 3 3 3 0 Coatomer WD associated region PNP_UDP_1 PF01048.15 EDN02970.1 - 2.1e-05 23.6 0.1 0.0005 19.1 0.1 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily Fungal_trans_2 PF11951.3 EDN02972.1 - 0.0083 14.7 1.3 0.016 13.8 0.9 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN02972.1 - 0.033 14.0 5.2 0.065 13.1 3.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EDN02973.1 - 1.4e-23 83.2 38.6 2e-23 82.6 26.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Met_10 PF02475.11 EDN02974.1 - 0.0005 19.7 0.0 0.00093 18.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EDN02974.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain EF-hand_6 PF13405.1 EDN02975.1 - 1.8e-09 36.6 0.0 0.0031 17.2 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EDN02975.1 - 3.3e-05 23.9 1.1 0.0017 18.4 0.1 2.8 2 2 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EDN02975.1 - 9.1e-05 21.4 0.0 0.00074 18.6 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EDN02975.1 - 0.078 12.6 0.0 0.15 11.6 0.0 1.6 1 1 0 1 1 1 0 EF-hand domain pair DUF342 PF03961.8 EDN02976.1 - 3 6.1 4.7 13 4.0 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) OB_NTP_bind PF07717.11 EDN02977.1 - 4.6e-24 84.4 0.0 1e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EDN02977.1 - 8.2e-24 83.5 0.1 3.5e-23 81.5 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDN02977.1 - 5.7e-11 42.1 0.0 1.8e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN02977.1 - 1.6e-06 27.7 0.3 3.2e-06 26.7 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDN02977.1 - 1.9e-05 24.8 0.1 0.00011 22.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EDN02977.1 - 0.00071 19.0 0.2 0.0019 17.6 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 EDN02977.1 - 0.00089 19.0 0.1 0.0017 18.1 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 EDN02977.1 - 0.0094 15.7 0.1 3.8 7.3 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EDN02977.1 - 0.045 13.7 0.0 0.19 11.7 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EDN02977.1 - 0.11 12.8 0.1 0.25 11.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter YfhO PF09586.5 EDN02977.1 - 0.11 10.5 0.1 0.15 10.0 0.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO AAA_29 PF13555.1 EDN02977.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRMT5 PF05185.11 EDN02978.1 - 8.7e-124 413.8 0.0 3.9e-79 266.6 0.0 2.1 2 0 0 2 2 2 2 PRMT5 arginine-N-methyltransferase GDPD PF03009.12 EDN02979.1 - 1.3e-43 149.3 0.0 1.7e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SPX PF03105.14 EDN02980.1 - 2.9e-26 92.8 0.2 3.7e-12 46.6 0.0 3.3 1 1 2 3 3 3 3 SPX domain Ank_2 PF12796.2 EDN02980.1 - 2.5e-22 79.0 0.4 3.4e-12 46.5 0.4 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDN02980.1 - 9e-20 70.6 1.4 6.7e-09 36.0 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EDN02980.1 - 9.2e-19 66.2 2.7 0.00069 19.3 0.1 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EDN02980.1 - 4.1e-15 55.4 2.3 2.6e-06 27.4 0.1 5.1 3 3 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN02980.1 - 2e-11 42.9 3.1 0.016 15.3 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat UNC45-central PF11701.3 EDN02981.1 - 1.2e-40 138.6 0.5 3.2e-40 137.3 0.1 2.0 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central RICTOR_N PF14664.1 EDN02981.1 - 0.0047 15.5 0.5 0.0084 14.7 0.1 1.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term Arm PF00514.18 EDN02981.1 - 0.025 14.4 8.7 1.9 8.4 0.0 5.0 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Tfb4 PF03850.9 EDN02982.1 - 4.9e-111 370.4 0.0 5.9e-111 370.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 EDN02982.1 - 0.015 15.4 0.1 0.035 14.1 0.1 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain Asparaginase_2 PF01112.13 EDN02983.1 - 1.8e-38 132.0 4.8 7.9e-24 83.9 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Actin PF00022.14 EDN02984.1 - 1.3e-89 300.3 0.0 2e-89 299.8 0.0 1.2 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EDN02984.1 - 0.00021 19.9 0.1 0.0087 14.6 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Methyltransf_31 PF13847.1 EDN02985.1 - 1.6e-07 31.0 0.0 3.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EDN02985.1 - 2.8e-06 26.2 0.1 7.8e-05 21.5 0.0 2.6 3 0 0 3 3 3 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_26 PF13659.1 EDN02985.1 - 0.0017 18.3 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN02985.1 - 0.0028 18.2 0.0 0.0075 16.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EDN02985.1 - 0.0036 16.8 0.0 0.017 14.6 0.0 2.0 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.7 EDN02985.1 - 0.016 15.6 0.0 0.049 14.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EDN02985.1 - 0.036 13.1 0.0 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_25 PF13649.1 EDN02985.1 - 0.045 14.1 0.0 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EDN02985.1 - 0.051 14.0 0.0 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain RNA_capsid PF03035.9 EDN02985.1 - 0.16 11.7 2.4 0.86 9.3 0.5 2.1 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein MTS PF05175.9 EDN02985.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 EDN02985.1 - 0.73 8.8 2.5 0.36 9.9 0.1 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_S5_C PF03719.10 EDN02986.1 - 7.9e-21 73.1 0.0 1.7e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EDN02986.1 - 3.4e-10 39.5 2.4 4.1e-10 39.2 0.4 2.0 1 1 1 2 2 2 1 Ribosomal protein S5, N-terminal domain HhH-GPD PF00730.20 EDN02986.1 - 0.0015 18.7 0.2 2.1 8.6 0.0 2.9 2 1 0 2 2 2 2 HhH-GPD superfamily base excision DNA repair protein DUF4473 PF14747.1 EDN02986.1 - 0.038 14.2 0.7 0.14 12.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) DASH_Dad3 PF08656.5 EDN02987.1 - 6.7e-17 60.9 0.0 6.7e-17 60.9 0.0 1.8 2 0 0 2 2 2 1 DASH complex subunit Dad3 BAF1_ABF1 PF04684.8 EDN02987.1 - 0.86 8.3 5.5 0.12 11.1 1.2 1.5 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Pkinase PF00069.20 EDN02988.1 - 2.4e-42 144.8 0.0 9.4e-22 77.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN02988.1 - 2.9e-15 56.0 0.0 2e-07 30.3 0.0 2.1 1 1 0 2 2 2 2 Protein tyrosine kinase DUF566 PF04484.7 EDN02989.1 - 5.9 6.3 8.2 3.8 6.9 4.7 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF566) CytadhesinP1 PF12378.3 EDN02989.1 - 7.8 6.5 7.2 16 5.5 5.0 1.5 1 0 0 1 1 1 0 Trypsin-sensitive surface-exposed protein His_Phos_2 PF00328.17 EDN02991.1 - 1.7e-07 30.8 0.0 1.9e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1097 PF06496.6 EDN02991.1 - 0.023 14.5 0.0 0.036 13.8 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1097) TRF PF08558.5 EDN02992.1 - 6.4e-91 303.9 0.7 1e-90 303.2 0.5 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EDN02992.1 - 1.5e-05 24.8 0.1 3.3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain TFIID_30kDa PF03540.8 EDN02993.1 - 7e-24 83.3 0.1 1.1e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 EDN02993.1 - 3.8 8.0 8.3 2.9 8.3 2.3 2.4 1 1 1 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_S19 PF00203.16 EDN02994.1 - 3.2e-19 68.3 0.0 5.3e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 IPK PF03770.11 EDN02995.1 - 2.2e-60 203.6 0.0 3.8e-60 202.9 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.5 EDN02996.1 - 5.7e-112 374.4 0.4 2.5e-55 187.9 1.0 3.1 1 1 2 3 3 3 3 Argonaute siRNA chaperone (ARC) complex subunit Arb1 HGTP_anticodon2 PF12745.2 EDN02996.1 - 0.22 10.6 2.9 0.33 10.0 2.0 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs ADH_zinc_N PF00107.21 EDN02997.1 - 8.8e-29 99.6 0.1 1.4e-28 99.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN02997.1 - 4e-23 82.6 0.0 8.5e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN02997.1 - 5.3e-11 42.2 0.0 1.2e-09 37.8 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.16 EDN02997.1 - 0.092 12.6 0.1 0.77 9.7 0.0 2.6 3 1 0 3 3 3 0 Chaperonin 10 Kd subunit Clp1 PF06807.9 EDN03000.1 - 3.8e-12 46.3 0.0 1.9e-05 24.5 0.0 2.9 2 1 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EDN03000.1 - 1.5e-07 31.1 0.0 3.6e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EDN03000.1 - 0.00093 18.8 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EDN03000.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EDN03000.1 - 0.11 12.7 0.4 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_35 PF14516.1 EDN03000.1 - 0.21 10.1 0.0 0.32 9.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain KilA-N PF04383.8 EDN03002.1 - 0.001 18.6 0.0 0.052 13.1 0.0 2.4 1 1 1 2 2 2 2 KilA-N domain Metallophos PF00149.23 EDN03003.1 - 4.2e-42 143.8 0.6 5.6e-42 143.4 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Adaptin_N PF01602.15 EDN03005.1 - 2e-72 244.2 0.0 2.5e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EDN03005.1 - 9.3e-08 32.2 0.7 0.18 12.0 0.0 3.9 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EDN03005.1 - 0.002 18.0 0.4 0.74 10.0 0.0 5.0 7 0 0 7 7 6 1 HEAT repeat HEAT_EZ PF13513.1 EDN03005.1 - 0.015 15.7 1.0 2.8 8.5 0.0 3.9 3 0 0 3 3 3 0 HEAT-like repeat Daxx PF03344.10 EDN03005.1 - 0.047 12.1 21.4 0.073 11.5 14.8 1.2 1 0 0 1 1 1 0 Daxx Family RasGEF_N_2 PF14663.1 EDN03005.1 - 0.059 13.3 0.5 0.36 10.7 0.1 2.4 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Nop14 PF04147.7 EDN03005.1 - 0.082 10.8 23.1 0.14 10.0 16.0 1.3 1 0 0 1 1 1 0 Nop14-like family Arm PF00514.18 EDN03005.1 - 0.084 12.7 3.5 1 9.2 0.2 3.6 4 0 0 4 4 3 0 Armadillo/beta-catenin-like repeat BUD22 PF09073.5 EDN03005.1 - 0.32 9.9 20.4 0.53 9.2 14.1 1.2 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.7 EDN03005.1 - 0.64 8.3 20.3 1 7.6 14.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 EDN03005.1 - 0.65 7.9 15.9 1 7.3 11.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.7 EDN03005.1 - 1.3 7.3 23.6 2.1 6.6 16.3 1.2 1 0 0 1 1 1 0 Mpp10 protein CENP-T PF15511.1 EDN03005.1 - 5.9 6.0 17.9 0.88 8.7 9.8 1.5 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T DUF1510 PF07423.6 EDN03005.1 - 7.2 5.9 22.7 15 4.8 15.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2457 PF10446.4 EDN03005.1 - 7.7 5.1 23.0 14 4.2 16.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nuf2 PF03800.9 EDN03007.1 - 1.5e-32 112.5 9.1 2.8e-17 63.0 0.1 4.0 3 2 1 4 4 4 2 Nuf2 family Reo_sigmaC PF04582.7 EDN03007.1 - 0.033 13.3 8.1 0.056 12.6 1.6 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IF-2B PF01008.12 EDN03008.1 - 5.3e-43 147.0 0.0 6.7e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 EDN03008.1 - 0.067 12.8 0.0 9.2 5.8 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain TPR_5 PF12688.2 EDN03008.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Tetratrico peptide repeat DUF1681 PF07933.9 EDN03010.1 - 6.3e-62 207.8 0.0 8.7e-62 207.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF1180 PF06679.7 EDN03010.1 - 9.1 6.1 9.9 14 5.5 2.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) DNA_binding_1 PF01035.15 EDN03013.1 - 0.061 13.0 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Thioredoxin PF00085.15 EDN03014.1 - 1.3e-27 95.5 0.3 1.5e-27 95.2 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EDN03014.1 - 3.4e-08 33.6 0.7 5.4e-07 29.8 0.5 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDN03014.1 - 1.6e-06 28.1 0.0 1.4e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EDN03014.1 - 6.8e-06 25.6 0.0 7.4e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EDN03014.1 - 3.5e-05 23.3 0.3 0.00071 19.1 0.2 2.0 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 EDN03014.1 - 0.0018 17.9 0.3 0.0066 16.1 0.2 1.8 1 1 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.11 EDN03014.1 - 0.0027 16.4 0.0 0.0033 16.1 0.0 1.1 1 0 0 1 1 1 1 Phosducin TraF PF13728.1 EDN03014.1 - 0.0092 15.4 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Glutaredoxin PF00462.19 EDN03014.1 - 0.0099 15.8 0.2 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.1 EDN03014.1 - 0.012 15.6 0.2 0.022 14.7 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_5 PF13743.1 EDN03014.1 - 0.035 13.6 0.1 0.11 12.0 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin HyaE PF07449.6 EDN03014.1 - 0.067 13.0 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF566 PF04484.7 EDN03015.1 - 9.4 5.6 7.4 4.3 6.7 2.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF566) OTU PF02338.14 EDN03016.1 - 1.2e-08 35.5 0.0 2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DAO PF01266.19 EDN03017.1 - 1.9e-22 79.6 1.0 8.4e-22 77.5 0.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN03017.1 - 0.011 15.7 0.1 0.032 14.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EDN03017.1 - 0.059 13.7 0.3 0.17 12.2 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN03017.1 - 0.12 11.4 2.4 0.17 10.9 0.1 2.3 3 0 0 3 3 3 0 Thi4 family FAD_binding_4 PF01565.18 EDN03018.1 - 6.7e-26 90.4 0.6 1.1e-25 89.6 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain COPI_assoc PF08507.5 EDN03019.1 - 3.4e-46 156.3 3.4 3.7e-46 156.2 2.4 1.0 1 0 0 1 1 1 1 COPI associated protein Bax1-I PF01027.15 EDN03019.1 - 0.0012 18.4 6.8 0.0014 18.2 4.7 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3995 PF13160.1 EDN03019.1 - 0.0065 16.5 0.8 0.0091 16.0 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3995) ATP_synt_I PF03899.10 EDN03019.1 - 1.7 8.8 8.9 1.8 8.7 5.5 1.5 1 1 0 1 1 1 0 ATP synthase I chain DUF3784 PF12650.2 EDN03019.1 - 4.4 7.3 9.1 1.3 9.0 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF751 PF05421.6 EDN03019.1 - 5.8 7.2 11.3 0.24 11.7 1.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF751) Rhomboid PF01694.17 EDN03019.1 - 6.8 6.7 9.9 8.5 6.3 6.9 1.1 1 0 0 1 1 1 0 Rhomboid family SdpI PF13630.1 EDN03019.1 - 7.2 6.4 11.5 0.67 9.6 0.9 2.3 2 0 0 2 2 2 0 SdpI/YhfL protein family ExoD PF06055.7 EDN03019.1 - 7.7 5.5 8.1 3.8 6.5 2.1 2.0 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD SPC12 PF06645.8 EDN03019.1 - 9 6.1 6.4 1.6 8.5 1.5 1.9 1 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) GATA PF00320.22 EDN03020.1 - 5.4e-29 99.2 17.9 1.3e-15 56.4 2.7 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EDN03020.1 - 7.1e-05 22.0 2.4 0.0098 15.1 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.13 EDN03020.1 - 0.0094 15.7 1.9 0.37 10.5 0.1 2.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.6 EDN03020.1 - 0.03 13.9 0.8 0.03 13.9 0.6 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 EDN03020.1 - 0.098 12.6 3.0 6.3 6.8 0.2 2.8 2 0 0 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.7 EDN03020.1 - 0.24 11.2 3.9 1.3 8.8 0.1 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.2 EDN03020.1 - 0.42 10.4 14.5 1e+03 -0.4 10.1 3.2 1 1 0 1 1 1 0 Double zinc ribbon eIF-5_eIF-2B PF01873.12 EDN03020.1 - 0.82 9.3 5.6 3.1 7.4 0.4 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 HypA PF01155.14 EDN03020.1 - 4 7.1 4.5 4.3 7.0 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family adh_short PF00106.20 EDN03022.1 - 6.6e-11 42.4 0.4 1e-10 41.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EDN03022.1 - 0.0011 18.4 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EDN03022.1 - 0.0013 18.6 0.1 0.0032 17.2 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN03022.1 - 0.048 13.3 0.2 0.075 12.6 0.1 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 EDN03022.1 - 0.077 12.9 2.5 0.16 12.0 0.7 2.2 3 0 0 3 3 3 0 NADH(P)-binding adh_short PF00106.20 EDN03025.1 - 1.4e-35 122.6 0.0 1.9e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN03025.1 - 1.9e-15 57.3 0.0 2.4e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN03025.1 - 2.6e-13 50.0 0.0 3.7e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EDN03025.1 - 0.0023 16.9 0.0 0.004 16.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EDN03025.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EDN03025.1 - 0.085 12.6 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EDN03025.1 - 0.086 11.9 1.4 0.9 8.5 0.0 2.7 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AAA_22 PF13401.1 EDN03025.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cofilin_ADF PF00241.15 EDN03026.1 - 5.3e-06 26.3 0.0 6.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3675 PF12428.3 EDN03026.1 - 0.03 14.5 0.2 0.04 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) NESP55 PF06390.7 EDN03027.1 - 0.018 14.4 1.5 0.018 14.4 1.1 2.1 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Nucleoplasmin PF03066.10 EDN03027.1 - 0.09 12.2 6.7 0.17 11.4 4.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 EDN03027.1 - 0.11 11.0 6.2 0.1 11.0 4.3 1.1 1 0 0 1 1 1 0 Daxx Family DUF3682 PF12446.3 EDN03027.1 - 0.15 12.3 6.5 0.3 11.3 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) FAM176 PF14851.1 EDN03027.1 - 0.55 9.8 3.3 0.91 9.1 2.3 1.3 1 0 0 1 1 1 0 FAM176 family Trypan_PARP PF05887.6 EDN03027.1 - 1.2 8.9 30.7 0.037 13.8 3.0 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) BSP_II PF05432.6 EDN03027.1 - 1.5 8.0 11.1 2.2 7.4 7.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PBP1_TM PF14812.1 EDN03027.1 - 1.7 8.9 6.3 4.3 7.7 4.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleo_P87 PF07267.6 EDN03027.1 - 2.8 6.5 7.3 3.9 6.0 5.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CobT PF06213.7 EDN03027.1 - 3.5 6.6 8.8 5 6.1 6.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HTH_29 PF13551.1 EDN03028.1 - 1.3e-07 31.7 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.10 EDN03028.1 - 1.6e-07 31.0 0.0 4.2e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_33 PF13592.1 EDN03028.1 - 1.7e-06 27.4 0.0 4.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EDN03028.1 - 2.3e-06 27.0 0.5 0.00017 21.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 EDN03028.1 - 5.1e-05 22.7 0.0 0.00065 19.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.13 EDN03028.1 - 0.00012 21.8 0.0 0.00018 21.1 0.0 1.3 1 1 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.1 EDN03028.1 - 0.00027 20.8 0.0 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EDN03028.1 - 0.0033 18.2 0.0 0.017 15.9 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_IS630 PF01710.11 EDN03028.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Transposase GerE PF00196.14 EDN03028.1 - 0.056 12.7 0.9 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Terminase_5 PF06056.7 EDN03028.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Trp_repressor PF01371.14 EDN03028.1 - 0.13 12.1 0.1 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Trp repressor protein MoCF_biosynth PF00994.19 EDN03029.1 - 2.4e-34 117.7 0.0 4.3e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.17 EDN03030.1 - 3.2e-45 153.4 0.2 3.8e-45 153.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN03030.1 - 2.3e-19 70.0 0.0 2.7e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN03030.1 - 2.3e-08 33.4 0.0 2.6e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDN03030.1 - 9.2e-07 28.4 0.1 8.6e-06 25.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDN03030.1 - 0.00073 19.4 0.0 0.00084 19.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase IstB_IS21 PF01695.12 EDN03030.1 - 0.018 14.4 0.6 0.41 10.0 0.1 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein Gtr1_RagA PF04670.7 EDN03030.1 - 0.031 13.4 0.1 0.037 13.1 0.1 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EDN03030.1 - 0.036 13.2 0.1 0.048 12.8 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EDN03030.1 - 0.14 11.5 0.1 0.27 10.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.14 EDN03032.1 - 3.8e-09 36.0 0.6 7.7e-08 31.7 0.4 2.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EDN03032.1 - 3.2e-05 22.9 0.2 0.00019 20.4 0.0 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN03032.1 - 0.0048 16.9 0.0 0.031 14.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EDN03032.1 - 0.011 14.4 0.4 0.026 13.1 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Patatin PF01734.17 EDN03032.1 - 0.067 13.1 0.6 0.21 11.4 0.3 1.9 2 0 0 2 2 2 0 Patatin-like phospholipase MFS_1 PF07690.11 EDN03033.1 - 1.1e-33 116.4 55.6 1.1e-33 116.4 38.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN03033.1 - 1.6e-12 46.4 25.0 3.6e-12 45.2 17.4 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4229 PF14012.1 EDN03033.1 - 1.4 8.8 9.8 1 9.2 3.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) FYVE_2 PF02318.11 EDN03035.1 - 0.039 13.8 14.5 0.67 9.8 1.3 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger zf-HC5HC2H PF13771.1 EDN03035.1 - 0.23 11.6 19.3 0.031 14.3 4.3 2.3 1 1 0 2 2 2 0 PHD-like zinc-binding domain Siva PF05458.7 EDN03035.1 - 0.33 10.5 16.2 0.43 10.1 1.4 2.5 3 0 0 3 3 3 0 Cd27 binding protein (Siva) zf-RING_6 PF14835.1 EDN03035.1 - 0.64 9.8 15.3 1.8 8.4 2.9 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EDN03035.1 - 7.4 6.3 24.9 4.4 7.1 4.5 2.6 2 1 0 2 2 2 0 zinc-RING finger domain DUF1735 PF08522.5 EDN03036.1 - 0.034 14.5 0.0 0.034 14.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1735) Copper-bind PF00127.15 EDN03037.1 - 0.00087 19.4 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family 2OG-FeII_Oxy PF03171.15 EDN03038.1 - 4.1e-15 55.8 0.0 6.4e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EDN03038.1 - 3.9e-13 49.9 0.0 6.5e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal UPF0086 PF01868.11 EDN03039.1 - 3.7e-29 100.1 0.1 5.5e-29 99.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 tRNA_int_endo PF01974.12 EDN03040.1 - 1.5e-16 59.9 0.0 3.5e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain PAXNEB PF05625.6 EDN03041.1 - 5e-122 407.2 0.0 6.1e-122 406.9 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein RNA_pol_Rpb8 PF03870.10 EDN03042.1 - 1.8e-27 96.2 0.0 2.1e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 NUDIX PF00293.23 EDN03043.1 - 1.7e-06 27.7 0.0 2.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF1956 PF09209.6 EDN03044.1 - 0.18 11.7 0.5 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1956) Tir_receptor_C PF07489.6 EDN03045.1 - 0.092 12.4 11.1 0.15 11.8 7.7 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus TMEM154 PF15102.1 EDN03045.1 - 0.21 11.2 5.8 0.24 11.0 4.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Dicty_REP PF05086.7 EDN03045.1 - 0.52 8.0 11.0 0.6 7.8 7.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 EDN03045.1 - 4.1 7.1 33.2 5.7 6.7 23.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein BSP_II PF05432.6 EDN03045.1 - 4.3 6.5 8.7 5 6.3 6.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) LRR_9 PF14580.1 EDN03046.1 - 5.7e-50 169.2 0.1 5.7e-50 169.2 0.1 1.7 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.1 EDN03046.1 - 1e-10 41.1 13.8 2.3e-06 27.2 2.9 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EDN03046.1 - 1.5e-09 37.2 13.0 7.1e-05 22.3 1.8 4.0 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EDN03046.1 - 0.028 14.4 8.3 9.9 6.6 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich Repeat HTH_38 PF13936.1 EDN03046.1 - 0.068 12.7 0.6 0.15 11.6 0.4 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain LRR_7 PF13504.1 EDN03046.1 - 0.29 11.5 5.6 58 4.5 0.1 4.6 4 1 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 EDN03046.1 - 3.4 8.0 5.9 1.1e+02 3.4 0.1 4.3 3 1 1 4 4 4 0 Leucine Rich repeat GDA1_CD39 PF01150.12 EDN03047.1 - 2.1e-96 323.0 0.0 3.4e-96 322.3 0.0 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Acyltransferase PF01553.16 EDN03048.1 - 5.1e-09 35.6 0.0 0.00011 21.6 0.0 2.6 1 1 1 2 2 2 2 Acyltransferase rve PF00665.21 EDN03050.1 - 5e-17 62.1 0.1 2.6e-16 59.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EDN03050.1 - 3.1e-15 55.5 2.8 7.4e-15 54.3 2.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EDN03050.1 - 0.0027 17.0 0.1 0.0067 15.8 0.0 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger DUF972 PF06156.8 EDN03051.1 - 0.00039 20.7 6.4 0.00067 19.9 0.1 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF972) MscS_porin PF12795.2 EDN03051.1 - 0.0011 18.2 15.6 0.0018 17.6 10.8 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Leu_zip PF15294.1 EDN03051.1 - 0.0031 16.6 5.3 0.0048 16.0 3.7 1.3 1 0 0 1 1 1 1 Leucine zipper DUF3552 PF12072.3 EDN03051.1 - 0.0044 16.2 12.7 0.0044 16.2 8.8 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) APG6 PF04111.7 EDN03051.1 - 0.025 13.6 8.1 0.036 13.1 5.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 EDN03051.1 - 0.027 13.1 6.2 0.04 12.5 4.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EDN03051.1 - 0.043 13.4 14.0 0.069 12.7 9.7 1.2 1 0 0 1 1 1 0 IncA protein IATP PF04568.7 EDN03051.1 - 0.054 13.5 1.0 0.17 11.9 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF4200 PF13863.1 EDN03051.1 - 0.13 12.1 13.7 0.27 11.1 9.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.3 EDN03051.1 - 0.17 11.6 9.7 0.1 12.3 0.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.7 EDN03051.1 - 0.18 11.5 1.3 0.43 10.3 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 EDN03051.1 - 0.29 8.9 3.9 0.4 8.4 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 EDN03051.1 - 2.8 6.8 10.7 4.1 6.2 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.6 EDN03051.1 - 3.5 7.3 12.9 4.5 6.9 0.5 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ADIP PF11559.3 EDN03051.1 - 6.9 6.5 15.8 17 5.2 10.9 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EDN03052.1 - 0.0011 19.2 0.1 0.0011 19.2 0.1 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF972) DUF3552 PF12072.3 EDN03052.1 - 0.0067 15.6 12.2 0.0067 15.6 8.5 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) MscS_porin PF12795.2 EDN03052.1 - 0.0095 15.2 17.3 0.016 14.5 12.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Spc7 PF08317.6 EDN03052.1 - 0.083 11.5 6.6 0.13 10.8 4.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 EDN03052.1 - 0.13 11.2 9.7 0.23 10.4 6.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 eIF3g PF12353.3 EDN03052.1 - 0.14 12.0 0.1 0.44 10.4 0.1 1.8 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G DUF4200 PF13863.1 EDN03052.1 - 0.18 11.7 13.7 0.48 10.3 9.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF1664 PF07889.7 EDN03052.1 - 0.34 10.7 1.1 0.63 9.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 EDN03052.1 - 0.37 10.6 9.8 0.2 11.5 0.7 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EDN03052.1 - 0.37 10.3 16.5 0.83 9.2 11.5 1.5 1 0 0 1 1 1 0 IncA protein ADIP PF11559.3 EDN03052.1 - 0.43 10.4 11.2 1.2 9.0 7.8 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 EDN03052.1 - 1.5 6.5 4.7 2.3 5.9 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 EDN03052.1 - 5.5 6.9 10.9 15 5.5 7.5 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 EDN03052.1 - 6.6 5.0 4.3 11 4.3 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 EDN03052.1 - 8 6.1 12.7 7.2 6.3 0.5 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 rve PF00665.21 EDN03053.1 - 9.5e-17 61.2 0.0 1.6e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EDN03053.1 - 8.4e-09 34.9 0.1 1.8e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 EDN03053.1 - 3.6e-05 23.2 0.0 6.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 EDN03053.1 - 0.038 13.6 0.1 0.075 12.6 0.1 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain SurA_N_3 PF13624.1 EDN03054.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain DUF3435 PF11917.3 EDN03055.1 - 8.8e-103 344.2 8.0 2.5e-91 306.5 1.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EDN03055.1 - 0.0095 15.6 0.1 0.079 12.6 0.1 2.5 1 1 0 1 1 1 1 Phage integrase family Pantoate_ligase PF02569.10 EDN03057.1 - 4.3e-83 278.3 0.0 1.9e-82 276.1 0.0 1.8 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Glyco_hydro_100 PF12899.2 EDN03057.1 - 0.11 10.8 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Alkaline and neutral invertase DEAD PF00270.24 EDN03058.1 - 1e-41 142.2 0.1 1.7e-41 141.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EDN03058.1 - 1.4e-19 69.3 0.0 3.1e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EDN03058.1 - 2e-19 69.2 0.0 4.6e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN03058.1 - 0.0031 17.3 0.0 0.0066 16.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WD40 PF00400.27 EDN03059.1 - 1.9e-05 24.3 0.1 0.00012 21.8 0.0 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat Pyridox_oxase_2 PF12766.2 EDN03060.1 - 2.9e-06 27.5 0.0 5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase POPLD PF08170.7 EDN03062.1 - 0.1 12.4 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 POPLD (NUC188) domain Dscam_C PF12355.3 EDN03063.1 - 0.0025 18.0 0.6 0.004 17.4 0.4 1.4 1 0 0 1 1 1 1 Down syndrome cell adhesion molecule C terminal adh_short PF00106.20 EDN03064.1 - 9.1e-15 54.9 0.2 1.6e-14 54.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN03064.1 - 0.00056 19.7 0.0 0.00069 19.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN03064.1 - 0.001 18.7 0.2 0.0019 17.9 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN03064.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF221 PF02714.10 EDN03067.1 - 5.7e-113 377.0 17.4 5.7e-113 377.0 12.1 3.0 4 0 0 4 4 4 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EDN03067.1 - 6.9e-47 158.9 0.8 6.9e-47 158.9 0.5 3.3 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EDN03067.1 - 5.2e-32 109.5 0.5 7.7e-31 105.8 0.1 2.6 3 0 0 3 3 3 1 Phosphate metabolism protein DUF4463 PF14703.1 EDN03067.1 - 6.8e-19 68.1 0.4 1.3e-18 67.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) CRPA PF05745.6 EDN03067.1 - 0.03 14.1 0.0 0.14 11.9 0.0 2.2 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) YajC PF02699.10 EDN03067.1 - 0.092 12.4 0.0 0.092 12.4 0.0 3.9 5 0 0 5 5 5 0 Preprotein translocase subunit FAM117 PF15388.1 EDN03067.1 - 0.23 10.6 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein Family FAM117 HisKA_2 PF07568.7 EDN03068.1 - 0.18 11.6 0.9 1.5 8.7 0.1 2.6 3 0 0 3 3 3 0 Histidine kinase MCM PF00493.18 EDN03069.1 - 7e-133 442.5 0.1 1.2e-132 441.7 0.1 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDN03069.1 - 7.1e-19 68.4 2.4 4.4e-18 65.9 0.0 2.9 3 1 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDN03069.1 - 1e-05 24.8 0.0 0.00019 20.6 0.0 2.8 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EDN03069.1 - 0.0023 17.4 0.0 0.006 16.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EDN03069.1 - 0.0026 17.4 0.0 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EDN03069.1 - 0.005 16.4 0.0 0.019 14.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Helicase_C PF00271.26 EDN03070.1 - 2.1e-07 30.6 0.0 3.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FNIP_N PF14636.1 EDN03072.1 - 1.8e-22 80.2 0.6 1.8e-22 80.2 0.4 4.3 4 1 0 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 EDN03072.1 - 0.01 15.4 1.6 0.067 12.7 0.2 2.3 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain DUF3608 PF12257.3 EDN03073.1 - 1.7e-67 227.2 0.0 9.2e-67 224.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3608) DEP PF00610.16 EDN03073.1 - 1.5e-29 101.5 1.0 3.1e-29 100.5 0.7 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Fungal_trans PF04082.13 EDN03075.1 - 2.3e-26 92.2 0.4 3.5e-26 91.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SH3_9 PF14604.1 EDN03076.1 - 2.4e-07 30.2 0.2 5.9e-07 28.9 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDN03076.1 - 0.00052 19.3 0.1 0.001 18.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain She9_MDM33 PF05546.6 EDN03077.1 - 6.6e-07 29.0 0.1 1.1e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family She9_MDM33 PF05546.6 EDN03078.1 - 4.1e-83 278.0 5.3 6.4e-83 277.4 3.7 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 EDN03078.1 - 0.015 14.8 4.7 0.021 14.3 0.7 2.2 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein UCR_TM PF02921.9 EDN03079.1 - 5.7e-19 68.1 2.4 1.1e-18 67.2 1.6 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EDN03079.1 - 6.3e-17 60.9 0.0 1e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FeoB_C PF07664.7 EDN03079.1 - 0.21 11.0 2.3 0.27 10.7 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B C terminus CBFD_NFYB_HMF PF00808.18 EDN03080.1 - 2.9e-11 43.2 0.7 6.3e-11 42.1 0.5 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Calcipressin PF04847.7 EDN03080.1 - 0.049 13.2 0.1 0.069 12.7 0.1 1.2 1 0 0 1 1 1 0 Calcipressin Voltage_CLC PF00654.15 EDN03081.1 - 8.2e-38 130.3 11.1 8.2e-38 130.3 7.7 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EDN03082.1 - 8.2e-14 51.1 0.0 1.5e-06 27.8 0.0 2.3 2 0 0 2 2 2 2 CBS domain EamA PF00892.15 EDN03083.1 - 0.00039 20.4 11.7 0.00067 19.6 8.1 1.5 1 1 0 1 1 1 1 EamA-like transporter family EmrE PF13536.1 EDN03083.1 - 0.0049 17.0 8.0 0.0049 17.0 5.6 1.8 1 1 1 2 2 2 1 Multidrug resistance efflux transporter DUF914 PF06027.7 EDN03083.1 - 0.0076 15.1 0.4 0.012 14.4 0.2 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) DUF2632 PF10943.3 EDN03083.1 - 0.0079 15.7 0.4 0.01 15.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2632) UPF0546 PF10639.4 EDN03083.1 - 0.058 13.2 1.9 0.075 12.8 1.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 TPT PF03151.11 EDN03083.1 - 0.68 9.5 9.7 4.9 6.7 7.1 1.9 1 1 1 2 2 2 0 Triose-phosphate Transporter family TPPK_C PF12555.3 EDN03083.1 - 2 8.2 7.0 17 5.2 1.2 2.7 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal PPR_2 PF13041.1 EDN03084.1 - 2.9e-45 151.9 8.5 5e-10 39.1 0.0 12.5 8 4 7 15 15 15 8 PPR repeat family PPR_3 PF13812.1 EDN03084.1 - 7.6e-34 113.1 17.0 1.6e-07 31.0 0.0 14.6 15 0 0 15 15 15 7 Pentatricopeptide repeat domain PPR PF01535.15 EDN03084.1 - 5e-30 101.3 10.3 0.00036 20.2 0.0 12.8 14 0 0 14 14 14 6 PPR repeat PPR_1 PF12854.2 EDN03084.1 - 2.4e-23 81.2 0.9 1.5e-07 30.7 0.0 10.1 10 0 0 10 10 10 4 PPR repeat RPM2 PF08579.6 EDN03084.1 - 1.8e-08 34.5 0.0 1.3e-05 25.3 0.0 4.4 5 0 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.1 EDN03084.1 - 3e-07 30.4 1.3 19 6.2 0.0 9.0 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDN03084.1 - 0.0015 18.7 0.3 1.3 9.4 0.0 5.4 6 1 0 6 6 6 1 Tetratricopeptide repeat ECSIT PF06239.6 EDN03084.1 - 0.0019 17.1 0.1 5.3 5.8 0.0 3.6 3 0 0 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway BTAD PF03704.12 EDN03084.1 - 0.0061 16.8 0.3 1.4 9.2 0.0 3.8 2 1 1 3 3 3 1 Bacterial transcriptional activator domain DUF1542 PF07564.6 EDN03084.1 - 0.021 14.7 0.4 0.048 13.6 0.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) PRANC PF09372.5 EDN03084.1 - 0.13 12.2 0.1 27 4.8 0.0 2.7 2 0 0 2 2 2 0 PRANC domain GHMP_kinases_N PF00288.21 EDN03085.1 - 5.2e-14 52.0 3.9 1.4e-12 47.4 0.3 3.1 3 0 0 3 3 3 2 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EDN03085.1 - 1.3e-08 34.9 0.0 3.4e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Rad60-SLD_2 PF13881.1 EDN03086.1 - 3e-10 39.9 0.3 7.3e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EDN03086.1 - 0.00015 21.1 0.0 0.00034 19.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EDN03086.1 - 0.091 12.9 0.5 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain UMP1 PF05348.6 EDN03087.1 - 1e-21 77.2 0.0 1.2e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Ribosom_S12_S23 PF00164.20 EDN03088.1 - 4.5e-32 110.0 0.3 7.7e-32 109.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Glyco_transf_15 PF01793.11 EDN03089.1 - 2e-137 457.6 14.1 2.3e-137 457.3 9.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.4 EDN03090.1 - 9.4e-244 811.3 22.3 7.6e-242 805.0 15.4 2.0 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Epimerase PF01370.16 EDN03091.1 - 1.2e-27 96.8 0.2 2.2e-22 79.6 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EDN03091.1 - 7.5e-26 89.8 0.1 1.5e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EDN03091.1 - 4.9e-12 45.1 0.0 6.8e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EDN03091.1 - 1e-06 27.8 0.0 1.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EDN03091.1 - 1.3e-06 28.3 0.0 2.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EDN03091.1 - 1.8e-05 24.8 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EDN03091.1 - 0.00013 20.9 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short_C2 PF13561.1 EDN03091.1 - 0.0028 17.4 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.9 EDN03091.1 - 0.0093 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain KR PF08659.5 EDN03091.1 - 0.011 15.4 0.0 0.021 14.4 0.0 1.4 1 1 0 1 1 1 0 KR domain NAD_binding_4 PF07993.7 EDN03091.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein DAO PF01266.19 EDN03091.1 - 0.02 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase adh_short PF00106.20 EDN03092.1 - 2.1e-12 47.2 0.0 2.1e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EDN03092.1 - 3.4e-08 33.3 0.0 6.7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EDN03092.1 - 0.00026 20.8 0.0 0.00084 19.1 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase G-patch PF01585.18 EDN03093.1 - 6.3e-06 25.8 0.5 1.4e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 G-patch domain Mito_fiss_reg PF05308.6 EDN03093.1 - 0.38 10.0 7.0 0.61 9.4 4.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Sec1 PF00995.18 EDN03094.1 - 7.3e-57 193.2 0.0 9.8e-55 186.2 0.0 2.1 1 1 0 1 1 1 1 Sec1 family DUF444 PF04285.7 EDN03094.1 - 0.02 13.5 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Apo-CIII PF05778.7 EDN03094.1 - 0.042 13.2 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Sec1 PF00995.18 EDN03095.1 - 5.8e-14 51.6 0.1 6.8e-14 51.4 0.1 1.0 1 0 0 1 1 1 1 Sec1 family DUF3983 PF13137.1 EDN03095.1 - 0.22 11.2 1.2 0.46 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3983) SUV3_C PF12513.3 EDN03096.1 - 1.3e-15 56.5 0.0 4.1e-15 54.9 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EDN03096.1 - 9.8e-06 25.3 0.0 3e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 EDN03097.1 - 3.6e-30 103.9 0.2 1e-29 102.5 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EDN03097.1 - 8.7e-26 89.9 0.0 2.3e-25 88.6 0.0 1.7 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EDN03097.1 - 5.1e-12 45.4 0.0 1.5e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EDN03097.1 - 9e-11 41.7 0.8 9e-11 41.7 0.6 1.8 2 0 0 2 2 2 1 S1 RNA binding domain DEAD PF00270.24 EDN03097.1 - 7.9e-06 25.4 0.1 2.1e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EDN03097.1 - 0.00022 20.2 0.0 0.00047 19.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EDN03097.1 - 0.00039 20.5 0.0 0.0013 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN03097.1 - 0.026 14.2 0.7 0.1 12.3 0.2 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 EDN03097.1 - 0.13 12.1 0.3 1.1 9.2 0.2 2.3 1 1 0 1 1 1 0 AAA domain Npa1 PF11707.3 EDN03099.1 - 1e-99 333.6 0.0 2.5e-99 332.4 0.0 1.7 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Creb_binding PF09030.5 EDN03099.1 - 0.045 13.9 1.6 0.18 11.9 0.0 2.8 3 0 0 3 3 3 0 Creb binding Vfa1 PF08432.5 EDN03101.1 - 0.43 10.5 12.9 2.1 8.3 0.2 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 UPRTase PF14681.1 EDN03102.1 - 1.6e-40 138.5 0.0 3e-40 137.6 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 EDN03102.1 - 2.7e-34 118.4 0.0 4.3e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CPT PF07931.7 EDN03102.1 - 7.1e-06 25.7 0.0 1.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 EDN03102.1 - 1.3e-05 25.5 0.1 3e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN03102.1 - 4.6e-05 24.2 0.0 0.00013 22.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDN03102.1 - 0.0049 15.9 0.0 0.018 14.1 0.0 2.0 2 1 1 3 3 3 1 Zeta toxin Cytidylate_kin2 PF13189.1 EDN03102.1 - 0.077 12.8 0.1 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 Cytidylate kinase-like family DUF87 PF01935.12 EDN03102.1 - 0.081 12.7 0.3 0.16 11.7 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF87 Pribosyltran PF00156.22 EDN03102.1 - 0.085 12.5 0.2 1.3 8.7 0.0 2.7 3 0 0 3 3 3 0 Phosphoribosyl transferase domain CLTH PF10607.4 EDN03103.1 - 1.7e-36 125.0 0.2 2.2e-36 124.7 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EDN03103.1 - 3.5e-09 36.1 0.0 6.5e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 LisH Pyr_redox_2 PF07992.9 EDN03104.1 - 5.1e-21 75.4 0.0 7.4e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN03104.1 - 2.1e-12 47.2 0.1 1.9e-10 40.9 0.0 3.3 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EDN03104.1 - 3e-07 29.2 0.2 9.3e-07 27.7 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EDN03104.1 - 1.9e-06 27.2 0.4 6.5e-06 25.6 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EDN03104.1 - 6.5e-06 26.1 0.0 2.5e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EDN03104.1 - 6.9e-06 25.1 0.8 6.9e-06 25.1 0.5 2.1 3 0 0 3 3 3 1 EF hand Nipped-B_C PF12830.2 EDN03105.1 - 6.5e-37 126.9 3.9 5.5e-36 123.9 0.1 3.7 3 1 1 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EDN03105.1 - 7.7e-13 48.0 4.4 1.8e-12 46.9 1.7 2.7 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EDN03105.1 - 5.6e-06 26.0 1.1 0.42 10.8 0.0 5.3 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 EDN03105.1 - 0.57 10.0 8.6 0.63 9.8 0.3 3.6 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 ABC2_membrane PF01061.19 EDN03106.1 - 3.3e-85 284.5 60.5 7.2e-45 152.7 14.4 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_trans_N PF14510.1 EDN03106.1 - 1.7e-24 85.7 0.0 3.3e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC_tran PF00005.22 EDN03106.1 - 2.5e-21 76.3 0.0 5.4e-14 52.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EDN03106.1 - 8.9e-09 34.9 8.4 6.7e-06 25.7 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter DUF3220 PF11516.3 EDN03106.1 - 0.036 14.0 0.0 0.44 10.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) FtsK_SpoIIIE PF01580.13 EDN03106.1 - 0.18 11.2 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC2_membrane_3 PF12698.2 EDN03106.1 - 1.4 7.9 51.8 0.062 12.3 8.6 3.1 3 0 0 3 3 3 0 ABC-2 family transporter protein HEAT_2 PF13646.1 EDN03107.1 - 1.8e-30 105.0 4.3 6.2e-14 52.0 0.0 3.8 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 EDN03107.1 - 1.7e-18 65.1 2.2 0.0031 17.8 0.0 6.4 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EDN03107.1 - 2.3e-07 31.0 9.0 0.028 14.8 0.0 5.0 3 2 3 6 6 6 3 HEAT-like repeat HEAT PF02985.17 EDN03107.1 - 1.9e-05 24.3 7.0 2.7 8.3 0.0 6.4 8 0 0 8 8 8 3 HEAT repeat Arm PF00514.18 EDN03107.1 - 0.024 14.4 1.0 25 4.8 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat ETC_C1_NDUFA4 PF04800.7 EDN03108.1 - 1.4e-37 127.5 1.3 2.2e-37 126.9 0.9 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.4 EDN03109.1 - 1.6e-40 137.2 0.2 1.8e-40 137.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EDN03109.1 - 0.0046 16.9 0.0 0.0056 16.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f MOZ_SAS PF01853.13 EDN03111.1 - 6.4e-85 283.1 0.0 9.2e-85 282.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EDN03111.1 - 5.4e-23 80.4 0.0 1.1e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EDN03111.1 - 0.032 13.9 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain HTH_9 PF08221.6 EDN03111.1 - 0.098 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Myb_Cef PF11831.3 EDN03112.1 - 1.8e-68 230.2 1.1 1.8e-68 230.2 0.8 3.5 3 1 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EDN03112.1 - 2.5e-19 69.0 3.7 1.2e-08 34.8 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN03112.1 - 1.5e-18 66.5 5.4 3.3e-12 46.3 0.9 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Nop53 PF07767.6 EDN03113.1 - 1.7e-121 405.8 30.3 2e-121 405.6 21.0 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) RNase_T PF00929.19 EDN03114.1 - 3.9e-26 92.2 0.0 5.7e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Exonuclease RNase_H2_suC PF08615.6 EDN03115.1 - 4.5e-32 110.7 0.1 5.7e-32 110.4 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) AF1Q PF15017.1 EDN03115.1 - 3.1 7.7 8.2 4.6 7.2 3.7 2.2 1 1 1 2 2 2 0 Drug resistance and apoptosis regulator Alk_phosphatase PF00245.15 EDN03116.1 - 3.5e-62 210.4 2.8 1e-30 106.7 0.0 2.3 2 1 0 2 2 2 2 Alkaline phosphatase Phosphodiest PF01663.17 EDN03116.1 - 5e-06 26.0 0.2 8.2e-06 25.3 0.1 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EDN03116.1 - 1.2e-05 24.6 1.5 9.6e-05 21.7 1.1 2.2 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EDN03116.1 - 0.014 13.8 0.2 0.021 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) HHH_3 PF12836.2 EDN03116.1 - 0.02 14.8 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif FTA4 PF13093.1 EDN03116.1 - 0.025 14.0 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DcpS_C PF11969.3 EDN03117.1 - 8.8e-30 103.3 0.0 1.3e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EDN03117.1 - 2.4e-29 101.9 0.0 4.5e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Peptidase_C12 PF01088.16 EDN03118.1 - 2.6e-63 213.0 0.0 3.1e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 EDN03118.1 - 0.014 15.9 0.0 0.058 13.9 0.0 1.8 1 1 1 2 2 2 0 Glyoxalase-like domain CH PF00307.26 EDN03118.1 - 0.094 12.7 0.0 12 5.9 0.0 2.2 2 0 0 2 2 2 0 Calponin homology (CH) domain MT-A70 PF05063.9 EDN03119.1 - 4.6e-21 75.1 0.1 2.5e-20 72.7 0.1 2.0 1 1 0 1 1 1 1 MT-A70 tRNA-synt_2 PF00152.15 EDN03120.1 - 4.1e-76 255.9 0.0 6.5e-76 255.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDN03120.1 - 1e-07 31.6 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1565 PF07602.6 EDN03120.1 - 0.096 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) DUF3763 PF12592.3 EDN03122.1 - 0.04 13.5 1.1 0.37 10.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) DUF1762 PF08574.5 EDN03125.1 - 8.1e-17 61.4 2.0 8.1e-17 61.4 1.4 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1762) Use1 PF09753.4 EDN03125.1 - 0.013 14.9 2.7 0.022 14.2 1.9 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 Bd3614_N PF14442.1 EDN03126.1 - 0.32 10.9 3.2 0.39 10.7 2.2 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal RRM_1 PF00076.17 EDN03127.1 - 1.6e-32 110.9 0.2 1.2e-11 44.0 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN03127.1 - 5.2e-30 103.2 0.1 1.8e-09 37.4 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN03127.1 - 3.4e-15 55.6 0.1 0.00011 22.0 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDN03127.1 - 1.9e-05 24.4 1.0 0.042 13.6 0.0 3.0 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.1 EDN03127.1 - 0.005 16.5 0.1 4.8 7.0 0.0 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.1 EDN03127.1 - 0.018 14.6 0.0 0.96 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) RNA_bind PF08675.6 EDN03127.1 - 0.02 14.8 0.3 0.15 12.0 0.0 2.5 3 1 0 3 3 3 0 RNA binding domain GST_N_3 PF13417.1 EDN03128.1 - 2.5e-09 37.2 0.0 4.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDN03128.1 - 8e-09 35.3 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EDN03128.1 - 5.7e-06 26.4 0.0 1.4e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain YL1 PF05764.8 EDN03129.1 - 4.9e-20 72.1 18.3 5.7e-20 71.9 12.7 1.1 1 0 0 1 1 1 1 YL1 nuclear protein PUF PF00806.14 EDN03130.1 - 1.1e-29 100.1 0.0 9.1e-06 24.8 0.0 6.0 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EDN03130.1 - 1e-09 37.8 0.0 3.6e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN03130.1 - 4.2e-07 29.7 0.0 9.9e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN03130.1 - 8e-05 22.5 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CAP59_mtransfer PF11735.3 EDN03131.1 - 3.9e-72 242.3 0.0 5.7e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF1349 PF07081.6 EDN03132.1 - 6.2e-25 87.6 0.0 7.9e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) ParA PF10609.4 EDN03133.1 - 5.3e-36 122.3 0.0 1.1e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EDN03133.1 - 5.2e-16 58.6 0.0 7.8e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EDN03133.1 - 6.3e-07 29.4 0.0 3.1e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EDN03133.1 - 1.2e-06 27.7 0.4 0.0002 20.5 0.1 2.9 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EDN03133.1 - 0.00039 19.5 0.0 0.00074 18.6 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 EDN03133.1 - 0.0023 17.5 0.0 0.65 9.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EDN03133.1 - 0.0098 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EDN03133.1 - 0.011 14.9 0.1 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EDN03133.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zn_Tnp_IS1595 PF12760.2 EDN03133.1 - 0.051 13.3 0.1 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain AAA_17 PF13207.1 EDN03133.1 - 0.063 14.0 0.0 0.089 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDN03133.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase VirE PF05272.6 EDN03133.1 - 0.19 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E T2SE PF00437.15 EDN03133.1 - 0.21 10.4 0.1 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Asp PF00026.18 EDN03135.1 - 1.7e-63 214.7 0.2 2.1e-63 214.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDN03135.1 - 1.7e-07 31.6 3.0 0.00087 19.7 0.4 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EDN03135.1 - 6.6e-07 29.4 0.0 4.1e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EDN03135.1 - 0.065 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease p450 PF00067.17 EDN03136.1 - 1.6e-46 158.8 0.0 2.1e-42 145.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Pkinase PF00069.20 EDN03137.1 - 2.3e-08 33.5 0.0 4.2e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Anp1 PF03452.9 EDN03138.1 - 6.4e-87 291.1 0.6 1.1e-86 290.4 0.0 1.6 2 0 0 2 2 2 1 Anp1 DUF2036 PF09724.4 EDN03139.1 - 6.1e-16 58.4 0.0 1.6e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2036) Lipl32 PF12103.3 EDN03140.1 - 0.069 12.6 0.0 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order UBACT PF02134.16 EDN03141.1 - 1.7e-40 136.4 2.2 8e-26 89.4 0.6 3.0 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein ThiF PF00899.16 EDN03141.1 - 4.8e-40 136.5 0.1 4.9e-20 71.7 0.0 2.9 3 0 0 3 3 3 2 ThiF family UBA_e1_C PF09358.5 EDN03141.1 - 1.4e-37 128.6 0.1 2.8e-37 127.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 EDN03141.1 - 5.8e-21 73.6 0.5 1.1e-20 72.6 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site GST_N_2 PF13409.1 EDN03142.1 - 6.5e-18 64.4 0.1 3.9e-17 61.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDN03142.1 - 5.1e-15 55.1 0.0 2e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EDN03142.1 - 4.4e-06 26.5 0.0 8.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDN03142.1 - 0.0089 16.4 0.0 0.021 15.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Amidohydro_1 PF01979.15 EDN03143.1 - 4.2e-21 75.9 0.8 2.1e-09 37.4 0.2 3.1 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EDN03143.1 - 6.4e-16 57.9 0.2 6.4e-16 57.9 0.2 2.6 2 1 1 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 EDN03143.1 - 6.1e-09 35.5 1.8 3.5e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EDN03143.1 - 7.9e-09 35.9 0.9 0.0013 18.8 0.1 2.8 3 1 0 3 3 3 2 Amidohydrolase Mito_carr PF00153.22 EDN03144.1 - 3.6e-55 183.6 4.6 3.3e-23 81.1 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EDN03144.1 - 3.5e-20 71.8 7.3 2.5e-13 49.9 0.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EDN03144.1 - 3.3e-18 63.5 7.4 7.3e-06 24.9 0.9 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EDN03144.1 - 1.5e-15 55.5 7.9 0.00023 20.7 0.4 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EDN03144.1 - 1.3e-14 52.7 6.3 8.3e-05 21.7 0.5 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EDN03144.1 - 9.7e-14 50.7 3.7 4.4e-07 29.4 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EDN03144.1 - 6.8e-07 29.3 0.6 0.00062 19.7 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EDN03144.1 - 0.0038 16.9 4.6 0.33 10.7 0.1 3.1 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand CRF PF00473.12 EDN03144.1 - 0.15 12.1 0.0 0.45 10.6 0.0 1.8 1 0 0 1 1 1 0 Corticotropin-releasing factor family MIP PF00230.15 EDN03145.1 - 2.8e-16 59.7 3.3 3.5e-16 59.3 2.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein HIRAN PF08797.6 EDN03148.1 - 0.023 14.5 0.5 0.062 13.2 0.0 2.0 2 1 0 2 2 2 0 HIRAN domain zf-TRAF PF02176.13 EDN03149.1 - 1.4e-10 41.4 36.2 2e-06 28.1 9.7 3.6 1 1 3 4 4 4 4 TRAF-type zinc finger K-box PF01486.12 EDN03149.1 - 0.039 13.7 0.2 0.6 9.9 0.0 2.3 2 1 0 2 2 2 0 K-box region bZIP_2 PF07716.10 EDN03149.1 - 0.046 13.5 0.8 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 Basic region leucine zipper RasGAP_C PF03836.10 EDN03149.1 - 0.12 12.0 0.0 0.85 9.2 0.0 2.1 2 0 0 2 2 2 0 RasGAP C-terminus DUF2205 PF10224.4 EDN03149.1 - 0.14 11.7 0.5 6.1 6.4 0.1 2.3 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Het-C PF07217.6 EDN03150.1 - 1.3e-223 743.6 0.0 1.5e-191 637.7 0.0 2.1 2 0 0 2 2 2 2 Heterokaryon incompatibility protein Het-C Spc97_Spc98 PF04130.8 EDN03151.1 - 1.4e-72 244.8 0.0 2.2e-72 244.1 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family MFS_1 PF07690.11 EDN03152.1 - 3.5e-30 104.9 17.0 3.5e-30 104.9 11.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EDN03152.1 - 4.2e-05 23.2 6.6 0.039 13.7 0.2 2.8 2 0 0 2 2 2 2 MFS_1 like family APH PF01636.18 EDN03153.1 - 1.6e-13 50.9 0.0 3.9e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family TPD52 PF04201.10 EDN03155.1 - 0.0049 16.6 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Tumour protein D52 family GILT PF03227.11 EDN03156.1 - 0.00045 20.0 0.0 0.0013 18.5 0.0 1.9 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_2 PF03727.11 EDN03157.1 - 2e-29 102.4 0.0 2.3e-23 82.6 0.0 2.3 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EDN03157.1 - 8.3e-19 67.7 0.0 4e-15 55.7 0.0 2.3 2 0 0 2 2 2 2 Hexokinase TFIIA_gamma_C PF02751.9 EDN03158.1 - 1.9e-27 94.8 2.1 2.6e-27 94.3 1.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EDN03158.1 - 2.1e-26 91.2 0.2 3e-26 90.7 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain SAB PF04382.8 EDN03159.1 - 0.046 13.4 0.0 0.17 11.6 0.0 2.0 1 0 0 1 1 1 0 SAB domain Kinesin-relat_1 PF12711.2 EDN03160.1 - 0.019 15.3 0.2 0.021 15.2 0.1 1.2 1 0 0 1 1 1 0 Kinesin motor Aldedh PF00171.17 EDN03161.1 - 1.1e-122 409.7 0.1 1.3e-122 409.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EDN03161.1 - 1.8e-07 30.2 0.0 1.7e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) Methyltransf_33 PF10017.4 EDN03162.1 - 9.9e-30 103.0 0.0 5.7e-29 100.5 0.0 2.1 2 0 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EDN03162.1 - 8.7e-20 71.1 0.5 5.3e-10 39.0 0.1 2.5 3 0 0 3 3 3 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EDN03162.1 - 0.00024 21.4 0.8 0.00075 19.8 0.1 2.2 2 0 0 2 2 2 1 DinB superfamily Methyltransf_25 PF13649.1 EDN03162.1 - 0.00065 20.0 0.0 0.0015 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF92 PF01940.11 EDN03163.1 - 1.5e-61 207.4 2.9 2e-61 207.0 2.0 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 4HBT PF03061.17 EDN03165.1 - 8.7e-10 38.5 0.0 7.7e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.1 EDN03165.1 - 0.36 10.5 7.3 2.6 7.6 5.0 2.2 1 1 0 1 1 1 0 Thioesterase-like superfamily RNA_pol PF00940.14 EDN03166.1 - 1e-166 554.4 0.1 2.8e-166 552.9 0.0 1.7 2 0 0 2 2 2 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EDN03166.1 - 1.3e-76 257.9 0.3 2.5e-76 256.9 0.2 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal ABC_tran_2 PF12848.2 EDN03166.1 - 4.2 7.2 9.5 2.6 7.9 0.2 3.3 3 0 0 3 3 3 0 ABC transporter Sin_N PF04801.8 EDN03167.1 - 1.6e-11 43.6 0.0 2.1e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region Rho_RNA_bind PF07497.7 EDN03167.1 - 0.026 14.1 0.1 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Rho termination factor, RNA-binding domain DEC-1_N PF04625.8 EDN03167.1 - 0.03 13.0 4.9 0.039 12.6 3.4 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region NIR_SIR PF01077.17 EDN03168.1 - 7.9e-06 25.3 0.0 1.1e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain POR_N PF01855.14 EDN03169.1 - 1.4e-09 37.7 0.0 2.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Pil1 PF13805.1 EDN03170.1 - 0.12 11.4 0.2 0.13 11.4 0.1 1.0 1 0 0 1 1 1 0 Eisosome component PIL1 MethyltransfD12 PF02086.10 EDN03171.1 - 0.044 13.2 2.3 0.063 12.7 1.6 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase G10 PF01125.12 EDN03171.1 - 5.8 6.4 6.9 0.77 9.3 0.9 2.3 3 0 0 3 3 3 0 G10 protein RVT_1 PF00078.22 EDN03172.1 - 1.2e-24 86.9 0.0 2.6e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 EDN03172.1 - 0.084 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase thumb domain RVT_2 PF07727.9 EDN03172.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EDN03173.1 - 0.00051 19.4 0.1 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger FEZ PF07763.8 EDN03173.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 FEZ-like protein DUF1729 PF08354.5 EDN03174.1 - 0.19 11.5 0.6 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) adh_short PF00106.20 EDN03175.1 - 3e-28 98.8 4.2 7.4e-14 52.0 0.1 2.7 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 EDN03175.1 - 5.7e-20 71.7 3.4 3.1e-12 46.5 0.1 2.4 2 0 0 2 2 2 2 KR domain Cas_Csy1 PF09611.5 EDN03176.1 - 0.087 11.7 0.5 0.14 11.0 0.4 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy1) Ras PF00071.17 EDN03177.1 - 5.7e-54 181.8 0.2 2.5e-53 179.7 0.1 1.8 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EDN03177.1 - 4.6e-17 62.6 0.0 9.4e-17 61.6 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN03177.1 - 5.9e-15 54.9 0.2 3.7e-13 49.0 0.1 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDN03177.1 - 1.9e-06 27.4 0.0 4.7e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDN03177.1 - 3.2e-05 23.8 0.0 5.6e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EDN03177.1 - 0.0025 16.9 0.1 0.013 14.6 0.1 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EDN03177.1 - 0.022 13.9 0.0 0.21 10.7 0.0 2.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EDN03177.1 - 0.044 13.5 0.1 3.4 7.4 0.0 2.4 2 1 0 2 2 2 0 Dynamin family DDHD PF02862.12 EDN03178.1 - 1.2e-31 110.2 0.0 1.2e-30 107.0 0.0 2.1 1 1 0 1 1 1 1 DDHD domain DUF2305 PF10230.4 EDN03178.1 - 0.0011 18.4 0.2 0.0019 17.6 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 EDN03178.1 - 0.0019 17.9 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN03178.1 - 0.0022 17.9 0.0 0.0024 17.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EDN03178.1 - 0.029 13.9 0.1 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.7 EDN03178.1 - 0.061 12.6 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Collagen PF01391.13 EDN03178.1 - 0.11 12.1 1.0 0.16 11.5 0.7 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) FAD_binding_3 PF01494.14 EDN03180.1 - 1.5e-11 43.9 0.0 2.3e-11 43.3 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EDN03180.1 - 0.065 13.1 0.0 0.068 13.0 0.0 1.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EDN03180.1 - 0.069 12.7 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Apis_Csd PF11671.3 EDN03181.1 - 0.18 11.5 14.8 0.2 11.4 10.2 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein MARVEL PF01284.18 EDN03181.1 - 0.33 10.7 2.8 0.34 10.7 1.9 1.1 1 0 0 1 1 1 0 Membrane-associating domain UPF0029 PF01205.14 EDN03182.1 - 0.17 11.5 0.3 0.29 10.8 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized protein family UPF0029 LSM PF01423.17 EDN03185.1 - 1.7e-20 72.2 0.2 2e-20 72.0 0.2 1.1 1 0 0 1 1 1 1 LSM domain APH PF01636.18 EDN03186.1 - 4.2e-09 36.4 0.0 6.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EDN03186.1 - 0.21 10.6 0.1 0.35 9.9 0.1 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF3431 PF11913.3 EDN03187.1 - 1.2e-34 119.7 0.0 1.5e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) zf-SNAP50_C PF12251.3 EDN03188.1 - 0.12 11.7 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Ras PF00071.17 EDN03189.1 - 2.8e-30 104.8 0.0 3.7e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN03189.1 - 3.2e-10 40.5 0.0 4.5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN03189.1 - 0.0001 21.6 0.0 0.00013 21.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDN03189.1 - 0.019 14.1 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EDN03189.1 - 0.022 13.9 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PAP2 PF01569.16 EDN03190.1 - 1.3e-13 50.7 2.3 1.3e-13 50.7 1.6 2.1 3 0 0 3 3 3 1 PAP2 superfamily Borealin PF10512.4 EDN03190.1 - 0.05 13.5 1.0 0.089 12.7 0.1 1.8 2 0 0 2 2 2 0 Cell division cycle-associated protein 8 DUF4073 PF13285.1 EDN03190.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) E1-E2_ATPase PF00122.15 EDN03192.1 - 2.7e-56 190.1 2.0 2.7e-56 190.1 1.4 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EDN03192.1 - 2.3e-27 96.7 0.0 3.9e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDN03192.1 - 4.8e-13 49.6 0.0 1.1e-12 48.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDN03192.1 - 3.3e-08 33.4 0.0 8.1e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_hydro_16 PF00722.16 EDN03194.1 - 0.00019 20.7 1.1 0.012 14.8 0.2 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Reo_sigmaC PF04582.7 EDN03195.1 - 1.2e-06 27.9 2.8 2.3e-06 27.0 1.9 1.4 1 0 0 1 1 1 1 Reovirus sigma C capsid protein ADIP PF11559.3 EDN03195.1 - 0.00056 19.8 5.7 0.00056 19.8 4.0 1.9 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EDN03195.1 - 0.00057 19.0 4.1 0.00098 18.2 2.8 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 Atg14 PF10186.4 EDN03195.1 - 0.00085 18.3 6.3 0.0016 17.4 4.4 1.5 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 LPP PF04728.8 EDN03195.1 - 0.0012 18.6 6.6 0.017 14.9 2.5 3.0 1 1 1 2 2 2 1 Lipoprotein leucine-zipper DUF1664 PF07889.7 EDN03195.1 - 0.0024 17.6 9.1 0.26 11.0 0.1 3.7 3 1 2 5 5 3 2 Protein of unknown function (DUF1664) COG5 PF10392.4 EDN03195.1 - 0.0027 17.6 3.5 0.0027 17.6 2.5 2.1 3 0 0 3 3 1 1 Golgi transport complex subunit 5 IncA PF04156.9 EDN03195.1 - 0.0031 17.1 5.9 0.0031 17.1 4.1 1.6 2 0 0 2 2 1 1 IncA protein WEMBL PF05701.6 EDN03195.1 - 0.0033 15.9 1.2 0.0048 15.4 0.8 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light TBPIP PF07106.8 EDN03195.1 - 0.0035 16.9 2.2 0.0035 16.9 1.6 2.0 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG16 PF08614.6 EDN03195.1 - 0.0053 16.6 10.2 0.013 15.3 4.5 2.5 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DHC_N2 PF08393.8 EDN03195.1 - 0.0079 14.7 1.1 0.012 14.1 0.8 1.3 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 TMF_TATA_bd PF12325.3 EDN03195.1 - 0.012 15.3 5.1 1 9.1 0.7 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2046 PF09755.4 EDN03195.1 - 0.016 14.0 3.0 0.036 12.9 1.6 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) CENP-F_leu_zip PF10473.4 EDN03195.1 - 0.019 14.8 5.2 0.29 10.9 1.2 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 EDN03195.1 - 0.023 14.4 1.7 0.023 14.4 1.1 1.8 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 EDN03195.1 - 0.041 13.7 8.3 0.18 11.6 5.8 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.6 EDN03195.1 - 0.047 13.0 3.8 0.12 11.7 2.6 1.7 2 0 0 2 2 1 0 Bacillus haemolytic enterotoxin (HBL) EzrA PF06160.7 EDN03195.1 - 0.05 11.7 2.9 0.18 9.9 1.9 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF2730 PF10805.3 EDN03195.1 - 0.055 13.1 5.5 2.9 7.6 0.2 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF2730) DUF2422 PF10337.4 EDN03195.1 - 0.068 11.9 0.7 0.091 11.5 0.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2422) Tup_N PF08581.5 EDN03195.1 - 0.077 13.2 1.9 0.2 11.8 0.3 2.3 1 1 1 2 2 2 0 Tup N-terminal Myosin_tail_1 PF01576.14 EDN03195.1 - 0.11 10.1 6.8 0.0078 13.9 1.4 1.3 2 0 0 2 2 2 0 Myosin tail GAS PF13851.1 EDN03195.1 - 0.14 11.3 4.1 0.033 13.3 0.7 1.6 2 0 0 2 2 1 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.17 EDN03195.1 - 0.16 12.0 1.9 0.35 10.9 0.5 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 EDN03195.1 - 0.16 10.5 6.4 0.019 13.6 1.7 1.5 2 0 0 2 2 1 0 Spc7 kinetochore protein DUF972 PF06156.8 EDN03195.1 - 0.22 11.8 8.8 4.3 7.7 0.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Nup54 PF13874.1 EDN03195.1 - 0.24 11.0 8.6 0.098 12.3 3.2 2.3 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Macoilin PF09726.4 EDN03195.1 - 0.26 9.5 10.6 0.016 13.5 3.2 1.8 2 1 1 3 3 3 0 Transmembrane protein DivIC PF04977.10 EDN03195.1 - 0.27 10.7 2.8 6.6 6.3 0.1 2.5 1 1 2 3 3 3 0 Septum formation initiator COG7 PF10191.4 EDN03195.1 - 0.27 9.0 7.3 1.4 6.7 2.4 2.2 1 1 1 2 2 2 0 Golgi complex component 7 (COG7) DUF3573 PF12097.3 EDN03195.1 - 0.29 9.6 4.7 0.62 8.6 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) Fib_alpha PF08702.5 EDN03195.1 - 0.31 11.1 10.5 3.9 7.5 0.3 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF904 PF06005.7 EDN03195.1 - 0.51 10.6 4.0 0.77 10.0 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Laminin_II PF06009.7 EDN03195.1 - 0.53 10.0 4.2 5.5 6.7 0.9 2.4 1 1 1 2 2 2 0 Laminin Domain II HALZ PF02183.13 EDN03195.1 - 0.53 10.0 5.7 1.2 8.9 0.1 2.8 2 1 1 3 3 2 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 EDN03195.1 - 0.62 9.8 7.8 1.7 8.3 1.7 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein MscS_porin PF12795.2 EDN03195.1 - 0.88 8.8 13.7 0.069 12.4 5.8 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Microtub_assoc PF07989.6 EDN03195.1 - 0.95 9.3 3.8 13 5.7 0.8 3.2 1 1 2 3 3 3 0 Microtubule associated DUF4618 PF15397.1 EDN03195.1 - 1 8.6 8.1 2.5 7.3 2.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) PspA_IM30 PF04012.7 EDN03195.1 - 1.4 8.2 5.2 4.3 6.6 1.0 2.3 1 1 1 2 2 2 0 PspA/IM30 family V-SNARE PF05008.10 EDN03195.1 - 1.6 8.9 7.1 2.3 8.4 2.1 2.8 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Dapper PF15268.1 EDN03195.1 - 2.3 6.9 9.0 0.81 8.4 4.3 1.6 2 0 0 2 2 2 0 Dapper Syntaxin PF00804.20 EDN03195.1 - 2.3 8.4 8.9 1.2 9.3 1.0 2.7 2 1 1 3 3 2 0 Syntaxin BRE1 PF08647.6 EDN03195.1 - 2.5 8.1 5.5 0.5 10.3 0.9 2.0 2 0 0 2 2 1 0 BRE1 E3 ubiquitin ligase DUF2968 PF11180.3 EDN03195.1 - 2.5 7.4 9.6 2 7.7 4.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) NPV_P10 PF05531.7 EDN03195.1 - 3 8.1 11.0 2.6 8.3 4.0 2.9 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein DUF4631 PF15450.1 EDN03195.1 - 4.3 5.4 13.4 17 3.4 6.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4631) WXG100 PF06013.7 EDN03195.1 - 4.9 7.2 6.6 9.7 6.2 1.0 3.3 2 1 2 4 4 3 0 Proteins of 100 residues with WXG YlqD PF11068.3 EDN03195.1 - 5.5 7.0 9.7 0.74 9.8 1.2 2.6 2 1 1 3 3 2 0 YlqD protein Vps51 PF08700.6 EDN03195.1 - 6.6 6.6 10.2 5.5 6.8 0.1 3.3 2 1 2 4 4 3 0 Vps51/Vps67 bZIP_2 PF07716.10 EDN03195.1 - 7.6 6.4 10.5 5.4 6.9 0.2 3.1 4 0 0 4 4 2 0 Basic region leucine zipper DUF948 PF06103.6 EDN03195.1 - 7.7 6.4 7.7 16 5.4 4.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DENN PF02141.16 EDN03197.1 - 4e-40 137.5 0.1 8.1e-40 136.5 0.0 1.5 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.13 EDN03197.1 - 7.3e-05 22.6 0.0 0.0003 20.6 0.0 2.1 2 0 0 2 2 2 1 uDENN domain zf-HIT PF04438.11 EDN03198.1 - 4.4e-10 39.0 10.3 7.2e-10 38.3 7.1 1.4 1 0 0 1 1 1 1 HIT zinc finger adh_short PF00106.20 EDN03199.1 - 1.3e-18 67.4 0.0 1.7e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN03199.1 - 2.8e-08 33.6 0.0 3.6e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EDN03199.1 - 5e-06 26.4 0.0 6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Asp_Glu_race PF01177.17 EDN03199.1 - 0.049 13.5 0.0 0.077 12.8 0.0 1.4 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase PA PF02225.17 EDN03199.1 - 0.059 13.0 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 PA domain RabGAP-TBC PF00566.13 EDN03200.1 - 6.2e-45 153.2 0.0 2.2e-44 151.5 0.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Death PF00531.17 EDN03200.1 - 0.012 15.3 0.6 0.086 12.6 0.1 2.6 2 0 0 2 2 2 0 Death domain Ank_2 PF12796.2 EDN03201.1 - 5.3e-30 103.6 0.0 1.8e-15 57.0 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDN03201.1 - 6e-25 85.7 0.4 0.00015 21.3 0.0 5.2 4 1 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EDN03201.1 - 4.8e-19 68.3 0.1 1.8e-08 34.6 0.0 5.0 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN03201.1 - 6.9e-19 66.0 0.0 0.0011 18.9 0.0 4.7 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EDN03201.1 - 1.2e-13 50.7 0.3 1.9e-06 27.9 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) F-box-like PF12937.2 EDN03201.1 - 6.7e-06 25.7 0.2 6.7e-06 25.7 0.1 1.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EDN03201.1 - 0.17 11.6 2.3 1.4 8.6 1.6 2.3 1 1 0 1 1 1 0 F-box domain TMF_TATA_bd PF12325.3 EDN03202.1 - 0.42 10.3 7.0 1.5 8.5 0.4 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FA_desaturase PF00487.19 EDN03203.1 - 3.3e-14 52.9 18.6 3.3e-14 52.9 12.9 2.1 1 1 1 2 2 2 1 Fatty acid desaturase WD40 PF00400.27 EDN03204.1 - 6.2e-16 57.6 8.1 1.8e-09 37.0 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat HEAT PF02985.17 EDN03204.1 - 1.5e-10 40.2 6.4 0.064 13.3 0.1 6.6 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EDN03204.1 - 1.1e-05 25.6 0.1 0.25 11.6 0.0 3.8 1 1 2 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 EDN03204.1 - 0.05 14.1 4.3 0.4 11.2 0.3 3.8 4 0 0 4 4 4 0 HEAT-like repeat CPSF_A PF03178.10 EDN03204.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 CPSF A subunit region NUDIX PF00293.23 EDN03208.1 - 9.1e-19 67.4 0.0 1.4e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF202 PF02656.10 EDN03209.1 - 1.2e-14 54.2 2.5 4.9e-14 52.2 1.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF202) TMEM187 PF15100.1 EDN03209.1 - 0.042 13.2 0.5 0.054 12.8 0.3 1.2 1 0 0 1 1 1 0 TMEM187 protein family COX4_pro_2 PF07835.7 EDN03209.1 - 0.09 12.7 1.0 0.42 10.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV CTP-dep_RFKase PF01982.11 EDN03209.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF120 MatE PF01554.13 EDN03210.1 - 2.3e-12 46.8 9.4 7.7e-09 35.3 0.8 2.5 2 1 1 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EDN03210.1 - 0.014 15.2 5.2 0.014 15.2 3.6 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DnaJ PF00226.26 EDN03211.1 - 5.9e-15 54.7 3.3 1e-14 54.0 0.5 2.6 3 0 0 3 3 3 1 DnaJ domain DEAD PF00270.24 EDN03212.1 - 2.3e-44 150.8 0.1 4.8e-44 149.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN03212.1 - 1.9e-21 75.6 0.0 5.5e-21 74.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EDN03212.1 - 4.4e-18 64.5 0.0 9.8e-18 63.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EDN03212.1 - 0.00058 19.7 0.4 0.002 17.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDN03212.1 - 0.00089 18.1 0.0 0.0017 17.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 EDN03212.1 - 0.0091 15.9 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DDE_Tnp_1_7 PF13843.1 EDN03213.1 - 2.4e-10 40.0 0.2 3e-10 39.6 0.2 1.3 1 0 0 1 1 1 1 Transposase IS4 Mur_ligase_C PF02875.16 EDN03213.1 - 0.14 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain DDE_1 PF03184.14 EDN03214.1 - 9.6e-52 175.2 0.0 1.7e-51 174.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN03214.1 - 2.1e-11 43.4 0.0 7.7e-11 41.6 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN03214.1 - 2.2e-10 39.9 0.2 5.5e-10 38.6 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN03214.1 - 4.4e-06 26.4 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease AA_permease PF00324.16 EDN03216.1 - 1.3e-123 412.8 42.9 1.6e-123 412.5 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDN03216.1 - 2.4e-39 135.0 48.1 3.2e-39 134.6 33.3 1.2 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.13 EDN03218.1 - 7.5e-05 22.5 12.0 0.00011 22.0 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 EDN03219.1 - 9.1e-45 152.1 0.1 2.7e-44 150.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN03219.1 - 1.5e-20 72.8 0.3 7.4e-20 70.6 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EDN03219.1 - 7e-19 67.3 2.1 7e-19 67.3 1.4 2.5 2 0 0 2 2 2 1 DBP10CT (NUC160) domain tRNA_anti-codon PF01336.20 EDN03220.1 - 1.2e-06 28.3 0.0 2.5e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.6 EDN03220.1 - 0.00022 21.5 0.0 0.00055 20.3 0.0 1.7 1 0 0 1 1 1 1 Replication protein A C terminal PAPS_reduct PF01507.14 EDN03221.1 - 2.6e-20 72.9 0.5 3.1e-14 53.1 0.1 2.3 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family PAPS_reduct PF01507.14 EDN03222.1 - 1.1e-19 70.8 0.0 1.2e-17 64.2 0.0 2.5 2 1 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family Kdo PF06293.9 EDN03222.1 - 0.0072 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.17 EDN03223.1 - 4e-10 39.1 0.0 1.3e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN03223.1 - 6.2e-07 29.2 0.0 2.4e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.15 EDN03224.1 - 1.6e-62 210.7 0.0 2.5e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EDN03224.1 - 1.4e-32 112.6 1.0 2.4e-32 111.8 0.7 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EDN03224.1 - 1.4e-22 80.2 0.0 8.4e-22 77.8 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain APH PF01636.18 EDN03226.1 - 0.00048 19.9 0.0 0.012 15.3 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family MOR2-PAG1_N PF14222.1 EDN03227.1 - 1.1e-146 489.7 0.0 1.3e-95 321.2 0.0 2.7 2 1 1 3 3 3 2 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EDN03227.1 - 2.2e-97 325.9 0.1 7.5e-97 324.1 0.0 2.0 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EDN03227.1 - 1.7e-38 131.9 8.7 4e-19 67.8 0.2 3.9 2 1 1 3 3 3 3 Cell morphogenesis central region HET PF06985.6 EDN03228.1 - 4.6e-21 75.4 0.0 8.6e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Corona_5a PF06336.6 EDN03228.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Coronavirus 5a protein NAD_binding_11 PF14833.1 EDN03229.1 - 1.6e-31 108.8 0.0 2.3e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EDN03229.1 - 5.4e-26 91.3 0.0 8.1e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CPSF_A PF03178.10 EDN03230.1 - 8.4e-78 261.6 0.0 4.9e-76 255.8 0.0 3.3 4 0 0 4 4 4 1 CPSF A subunit region MMS1_N PF10433.4 EDN03230.1 - 5.7e-73 245.7 0.0 6.3e-62 209.3 0.0 2.5 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF2460 PF09343.5 EDN03230.1 - 0.12 11.6 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) PGA2 PF07543.7 EDN03231.1 - 9.6e-50 168.0 0.4 1.1e-49 167.8 0.3 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 CENP-S PF15630.1 EDN03232.1 - 1e-29 102.5 0.0 1.3e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EDN03232.1 - 4.3e-07 29.5 0.0 5.7e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EDN03232.1 - 0.00051 19.7 0.0 0.00086 18.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated DUF2235 PF09994.4 EDN03235.1 - 1.2e-105 352.8 0.0 2.1e-105 352.0 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.10 EDN03236.1 - 2.2e-92 310.1 0.0 5.5e-80 269.2 0.0 2.3 1 1 1 2 2 2 2 Animal haem peroxidase TPR_12 PF13424.1 EDN03236.1 - 2.9e-16 59.1 0.1 3.4e-08 33.3 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EDN03236.1 - 4.8e-08 32.6 0.0 0.0023 17.7 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDN03236.1 - 1.7e-06 27.6 0.2 0.093 12.3 0.0 3.3 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 EDN03236.1 - 0.0027 17.2 0.8 4.3 7.1 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDN03236.1 - 0.0058 16.4 0.4 3.8 7.6 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDN03236.1 - 0.05 13.4 0.2 14 5.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_31 PF01055.21 EDN03237.1 - 9.2e-167 555.3 1.0 1.2e-166 555.0 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EDN03237.1 - 0.0084 15.9 0.9 0.025 14.4 0.3 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like Hexapep_2 PF14602.1 EDN03238.1 - 3e-06 26.6 0.8 0.00062 19.2 0.3 3.0 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 EDN03238.1 - 7.1e-06 25.2 9.8 0.00072 18.9 2.0 4.4 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 EDN03238.1 - 0.09 11.3 0.1 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 L-fucokinase Arf PF00025.16 EDN03239.1 - 1.7e-29 102.3 0.0 2e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDN03239.1 - 0.0051 16.0 0.1 0.0065 15.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit F-box-like PF12937.2 EDN03241.1 - 0.0055 16.3 0.4 0.025 14.2 0.3 2.0 1 1 0 1 1 1 1 F-box-like MFS_1 PF07690.11 EDN03242.1 - 1.4e-17 63.4 8.4 1.9e-17 63.0 5.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN03242.1 - 6.5e-06 24.9 0.2 6.7e-06 24.9 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MCM PF00493.18 EDN03243.1 - 1.1e-137 458.3 0.0 1.5e-137 457.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EDN03243.1 - 1.5e-36 125.7 33.8 1.5e-36 125.7 23.5 2.2 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EDN03243.1 - 1.8e-18 67.2 0.0 3.9e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDN03243.1 - 1.8e-08 33.7 0.1 2.6e-06 26.7 0.0 2.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDN03243.1 - 1e-05 25.2 0.1 7e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EDN03243.1 - 0.0003 20.4 0.0 0.0021 17.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDN03243.1 - 0.002 17.6 0.2 0.022 14.2 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain zf-TFIIB PF13453.1 EDN03243.1 - 0.018 14.2 1.0 0.038 13.1 0.7 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger PHD PF00628.24 EDN03244.1 - 0.094 12.4 3.2 0.41 10.3 1.0 2.5 2 0 0 2 2 2 0 PHD-finger Pkinase PF00069.20 EDN03245.1 - 3.8e-31 108.2 0.0 3.2e-27 95.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN03245.1 - 5.5e-12 45.3 0.0 8.1e-11 41.4 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase DUF1688 PF07958.6 EDN03246.1 - 4.2e-128 427.4 0.0 4.9e-128 427.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Sugar_tr PF00083.19 EDN03247.1 - 4.8e-81 272.6 17.3 6.5e-81 272.2 12.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN03247.1 - 2.8e-27 95.3 68.0 2e-24 86.0 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EDN03247.1 - 0.0003 19.1 3.2 0.0003 19.1 2.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TPT PF03151.11 EDN03249.1 - 9.5e-15 54.5 18.7 1.1e-14 54.3 5.7 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EDN03249.1 - 3.7e-05 23.7 8.9 3.7e-05 23.7 6.2 2.4 2 0 0 2 2 2 2 EamA-like transporter family MIS13 PF08202.6 EDN03250.1 - 2.8e-26 92.2 4.7 1.4e-12 47.2 0.2 2.6 1 1 1 2 2 2 2 Mis12-Mtw1 protein family TSC22 PF01166.13 EDN03250.1 - 0.013 15.4 0.1 0.037 13.9 0.1 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.10 EDN03250.1 - 0.058 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator AT_hook PF02178.14 EDN03250.1 - 0.066 12.9 0.7 0.066 12.9 0.5 3.4 4 0 0 4 4 4 0 AT hook motif SNAPc19 PF15497.1 EDN03250.1 - 0.093 12.9 3.9 1 9.5 0.6 2.7 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 PS_Dcarbxylase PF02666.10 EDN03251.1 - 2.8e-52 176.9 0.0 4e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EDN03251.1 - 4.5e-34 116.1 0.0 3.8e-17 61.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.27 EDN03251.1 - 0.0035 16.5 0.0 0.012 14.8 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EDN03251.1 - 0.0043 17.1 0.1 0.012 15.7 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EDN03251.1 - 0.0093 15.7 0.0 0.042 13.7 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EDN03251.1 - 0.028 13.7 0.0 0.088 12.1 0.0 1.9 1 0 0 1 1 1 0 EF hand Ank PF00023.25 EDN03252.1 - 2.8e-20 71.0 0.0 4.5e-06 26.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EDN03252.1 - 5e-19 68.4 0.1 2.7e-10 40.4 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDN03252.1 - 4.5e-14 52.5 0.1 1.1e-08 35.3 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN03252.1 - 1.2e-11 44.4 0.3 9.2e-07 28.9 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN03252.1 - 1.9e-11 43.0 0.0 0.00081 19.4 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat DUF2288 PF10052.4 EDN03252.1 - 0.077 12.7 0.6 0.23 11.1 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2288) Ank PF00023.25 EDN03254.1 - 5.9e-14 51.0 3.3 3.8e-10 39.0 0.2 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EDN03254.1 - 3.9e-13 49.5 0.2 1.2e-08 35.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDN03254.1 - 1.9e-11 43.8 0.4 1.9e-07 31.0 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN03254.1 - 2.1e-10 40.8 0.5 1.5e-06 28.5 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN03254.1 - 1.3e-09 37.3 0.4 1.8e-06 27.6 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EDN03254.1 - 0.00011 21.7 0.0 0.00064 19.3 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain tRNA_bind_2 PF13725.1 EDN03254.1 - 0.36 10.9 5.3 13 5.9 0.1 2.9 1 1 1 2 2 2 0 Possible tRNA binding domain GCS PF03074.11 EDN03256.1 - 2.5e-151 503.9 0.0 2.1e-149 497.5 0.0 2.1 1 1 0 1 1 1 1 Glutamate-cysteine ligase VIT PF08487.5 EDN03259.1 - 5.7e-22 77.6 0.0 1.6e-21 76.1 0.0 1.7 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.1 EDN03259.1 - 1.4e-17 63.7 0.0 3.1e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EDN03259.1 - 4.5e-13 48.4 0.0 1.2e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EDN03259.1 - 1.7e-05 25.0 0.0 3.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EDN03259.1 - 0.00012 21.8 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain CobT_C PF11775.3 EDN03259.1 - 0.0068 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT VWA domain GATA PF00320.22 EDN03260.1 - 7.9e-15 53.9 5.2 1.9e-14 52.7 3.6 1.7 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 EDN03260.1 - 0.27 11.2 1.9 0.57 10.2 1.3 1.5 1 0 0 1 1 1 0 zinc-finger Acetyltransf_4 PF13420.1 EDN03263.1 - 3.5e-05 23.8 0.0 0.00017 21.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDN03263.1 - 0.014 15.5 0.0 0.024 14.8 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN03263.1 - 0.024 14.6 0.0 0.047 13.7 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family HGTP_anticodon PF03129.15 EDN03263.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain Macro PF01661.16 EDN03264.1 - 1.8e-40 137.5 0.1 2.7e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 Macro domain GLTP PF08718.6 EDN03267.1 - 1.1e-38 132.5 0.0 1.7e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) E1-E2_ATPase PF00122.15 EDN03268.1 - 6.6e-21 74.4 0.0 2.5e-20 72.5 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EDN03268.1 - 8.9e-06 26.2 0.4 0.063 13.6 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDN03268.1 - 8.6e-05 22.7 3.9 0.02 15.0 2.7 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDN03268.1 - 0.006 16.1 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EDN03268.1 - 0.14 11.3 0.5 0.48 9.6 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Ank_2 PF12796.2 EDN03269.1 - 3.6e-36 123.3 12.4 7.3e-16 58.2 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EDN03269.1 - 6.7e-22 76.1 5.4 6.1e-06 25.7 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EDN03269.1 - 1.4e-20 73.2 2.6 3.4e-09 36.9 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN03269.1 - 1.5e-16 58.8 2.5 0.0032 17.5 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EDN03269.1 - 3.7e-16 58.7 4.8 1.8e-07 31.1 0.1 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) FYVE PF01363.16 EDN03270.1 - 5e-06 26.3 11.4 9e-06 25.4 6.8 2.0 2 0 0 2 2 2 1 FYVE zinc finger zf-AN1 PF01428.11 EDN03270.1 - 0.00087 19.1 4.0 0.00087 19.1 2.8 2.0 3 0 0 3 3 3 1 AN1-like Zinc finger zf-Di19 PF05605.7 EDN03270.1 - 0.029 14.4 0.0 0.029 14.4 0.0 2.3 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.16 EDN03270.1 - 1.7 8.5 11.3 0.12 12.2 1.7 2.6 2 1 1 3 3 3 0 IBR domain PKD_channel PF08016.7 EDN03271.1 - 7.3e-05 21.3 19.1 0.0022 16.5 13.0 2.2 1 1 0 1 1 1 1 Polycystin cation channel CAML PF14963.1 EDN03271.1 - 1 8.6 3.9 1.7 7.9 2.7 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand EIF_2_alpha PF07541.7 EDN03272.1 - 3.2e-38 129.9 0.0 7.3e-38 128.8 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EDN03272.1 - 7.7e-13 48.3 1.0 1.8e-12 47.1 0.7 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Sulfate_transp PF00916.15 EDN03273.1 - 9e-41 139.7 8.4 9e-41 139.7 5.8 2.4 1 1 1 2 2 2 1 Sulfate transporter family STAS PF01740.16 EDN03273.1 - 2e-09 36.8 0.0 5.9e-09 35.3 0.0 1.8 1 1 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EDN03273.1 - 0.0021 18.0 0.0 0.0052 16.7 0.0 1.6 1 0 0 1 1 1 1 STAS domain DUF1286 PF06939.6 EDN03273.1 - 1.1 9.4 9.3 5.3 7.2 3.0 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1286) CENP-L PF13092.1 EDN03274.1 - 7.4e-58 194.9 0.1 9.9e-58 194.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Palm_thioest PF02089.10 EDN03276.1 - 2.3e-44 151.4 0.2 3.2e-25 88.6 0.0 2.0 1 1 1 2 2 2 2 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 EDN03276.1 - 0.00026 20.6 0.0 0.00056 19.5 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF915 PF06028.6 EDN03276.1 - 0.00068 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF3328 PF11807.3 EDN03277.1 - 4.4e-13 49.4 0.8 5.7e-13 49.0 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) RNase_H2-Ydr279 PF09468.5 EDN03277.1 - 0.094 11.8 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) AlaDh_PNT_N PF05222.10 EDN03281.1 - 5.9e-24 84.6 0.0 9e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EDN03281.1 - 1.2e-11 44.5 0.0 1.8e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF2675 PF11247.3 EDN03281.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) BAR PF03114.13 EDN03282.1 - 1.1e-60 205.0 7.4 1.3e-60 204.7 5.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EDN03282.1 - 2.5e-16 58.7 0.1 5.4e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDN03282.1 - 1.1e-11 44.1 0.0 2.1e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDN03282.1 - 1.7e-09 36.9 0.1 4.7e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.5 EDN03282.1 - 0.14 11.3 10.9 1.3 8.2 7.5 2.0 1 1 0 1 1 1 0 Vps5 C terminal like YlqD PF11068.3 EDN03282.1 - 0.76 9.8 7.5 2.6 8.0 0.0 3.1 2 1 1 3 3 3 0 YlqD protein Aminotran_5 PF00266.14 EDN03283.1 - 3.2e-96 322.2 0.0 8.8e-96 320.8 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V FAD_binding_4 PF01565.18 EDN03283.1 - 2.7e-18 65.7 0.0 1.3e-17 63.5 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Beta_elim_lyase PF01212.16 EDN03283.1 - 4.9e-07 29.1 0.0 7.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase BBE PF08031.7 EDN03283.1 - 3.6e-05 23.5 0.0 7.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DegT_DnrJ_EryC1 PF01041.12 EDN03283.1 - 0.0019 17.3 0.0 0.0044 16.1 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EDN03283.1 - 0.046 12.1 0.0 0.07 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Cytokin-bind PF09265.5 EDN03283.1 - 0.18 10.9 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding IDO PF01231.13 EDN03284.1 - 4.5e-171 568.9 0.0 5.2e-171 568.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EDN03284.1 - 0.0029 16.2 0.0 0.0082 14.7 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1864) CsbD PF05532.7 EDN03285.1 - 4.4e-07 29.4 8.1 4.4e-07 29.4 5.6 3.2 2 1 1 3 3 3 2 CsbD-like PP28 PF10252.4 EDN03285.1 - 1.1 9.3 10.7 0.28 11.2 2.5 2.1 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 ERG2_Sigma1R PF04622.7 EDN03286.1 - 3.4e-39 134.3 0.1 8.1e-39 133.1 0.1 1.5 1 1 0 1 1 1 1 ERG2 and Sigma1 receptor like protein UEV PF05743.8 EDN03287.1 - 3.2e-37 126.8 0.0 5.5e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EDN03287.1 - 2.3e-19 68.7 0.2 7.7e-19 67.0 0.0 2.0 2 0 0 2 2 2 1 Vps23 core domain ADIP PF11559.3 EDN03287.1 - 3.2e-05 23.8 3.6 3.2e-05 23.8 2.5 1.6 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EDN03287.1 - 0.0026 17.0 7.6 0.0037 16.5 5.3 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein UQ_con PF00179.21 EDN03287.1 - 0.0081 15.5 0.1 0.02 14.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Cep57_MT_bd PF06657.8 EDN03287.1 - 0.011 15.6 0.4 0.034 14.0 0.2 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Fib_alpha PF08702.5 EDN03287.1 - 0.015 15.3 0.0 0.051 13.6 0.0 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 EDN03287.1 - 0.057 13.7 3.1 0.11 12.8 2.1 1.5 1 0 0 1 1 1 0 Snapin/Pallidin DUF904 PF06005.7 EDN03287.1 - 0.1 12.8 0.1 0.27 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Prominin PF05478.6 EDN03287.1 - 0.23 8.9 4.4 0.33 8.4 3.0 1.1 1 0 0 1 1 1 0 Prominin Salt_tol_Pase PF09506.5 EDN03287.1 - 0.43 9.0 2.8 1.6 7.2 1.9 1.7 1 1 1 2 2 2 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) STE2 PF02116.10 EDN03288.1 - 5.2e-103 343.9 24.1 6.1e-103 343.7 16.7 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Abhydrolase_9_N PF15420.1 EDN03288.1 - 4.1 7.1 14.5 0.56 9.9 3.4 2.2 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Kdo PF06293.9 EDN03289.1 - 1.6e-07 30.5 0.0 0.0014 17.7 0.0 3.6 4 0 0 4 4 4 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN03289.1 - 1.6e-06 28.0 0.0 0.001 18.8 0.0 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EDN03289.1 - 0.00087 18.5 0.0 0.0042 16.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EDN03289.1 - 0.018 14.4 0.0 0.97 8.7 0.0 2.4 2 0 0 2 2 2 0 RIO1 family Clat_adaptor_s PF01217.15 EDN03290.1 - 1.4e-50 170.6 1.7 1.6e-50 170.4 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.5 EDN03291.1 - 1e-41 142.7 0.1 2.2e-41 141.6 0.0 1.5 2 0 0 2 2 2 1 Maf1 regulator Type_III_YscX PF09474.5 EDN03291.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) Snapin_Pallidin PF14712.1 EDN03292.1 - 0.00014 22.1 2.7 0.042 14.1 0.0 2.7 3 0 0 3 3 3 2 Snapin/Pallidin PAT1 PF09770.4 EDN03292.1 - 0.11 10.7 18.7 0.15 10.2 13.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EDN03292.1 - 0.21 10.9 21.7 0.25 10.7 15.0 1.1 1 0 0 1 1 1 0 Vta1 like GAS PF13851.1 EDN03292.1 - 1.3 8.1 12.5 0.2 10.8 2.1 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding COPIIcoated_ERV PF07970.7 EDN03293.1 - 8.5e-31 107.3 0.0 1.9e-29 102.8 0.0 2.0 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EDN03293.1 - 0.0064 16.4 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.20 EDN03294.1 - 1.7e-33 115.8 0.3 2.3e-33 115.4 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN03294.1 - 2.7e-12 46.3 0.2 3.7e-12 45.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN03294.1 - 0.0025 17.5 0.1 0.055 13.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDN03294.1 - 0.034 13.5 0.1 0.085 12.1 0.0 1.7 1 1 1 2 2 2 0 RIO1 family Choline_kinase PF01633.15 EDN03294.1 - 0.045 13.3 0.6 0.15 11.6 0.3 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase Slu7 PF11708.3 EDN03296.1 - 2.2e-79 266.6 22.0 2.2e-79 266.6 15.3 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EDN03296.1 - 0.019 14.6 0.8 0.04 13.5 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle DNA_pol_B_exo1 PF03104.14 EDN03297.1 - 4.3e-11 42.2 0.1 6.1e-11 41.7 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EDN03298.1 - 3.1e-19 69.1 0.0 4.3e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EDN03298.1 - 1.1e-15 57.3 0.0 1.6e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain Acetyltransf_9 PF13527.1 EDN03299.1 - 0.0071 16.1 0.0 0.057 13.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDN03299.1 - 0.0074 16.4 0.1 0.065 13.3 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN03299.1 - 0.028 14.4 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_1 PF00583.19 EDN03300.1 - 9.3e-06 25.5 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN03300.1 - 5e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDN03300.1 - 0.00078 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDN03300.1 - 0.0032 17.5 0.0 0.0066 16.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EDN03300.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 EDN03300.1 - 0.029 14.0 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Ank_2 PF12796.2 EDN03301.1 - 1.1e-34 118.5 13.5 2e-09 37.6 0.3 6.0 1 1 7 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDN03301.1 - 6.4e-26 90.2 4.9 2.4e-05 24.7 0.1 7.8 6 1 2 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.25 EDN03301.1 - 7.2e-26 88.6 2.5 6.8e-05 22.4 0.0 9.6 9 1 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.1 EDN03301.1 - 2.8e-25 87.7 6.8 0.00018 21.5 0.0 8.0 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN03301.1 - 8.2e-19 65.8 5.1 0.035 14.3 0.0 9.6 10 0 0 10 10 10 4 Ankyrin repeat Snf7 PF03357.16 EDN03301.1 - 0.12 11.7 0.2 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Snf7 I_LWEQ PF01608.12 EDN03303.1 - 2.9e-64 215.6 8.0 2.9e-64 215.6 5.6 6.1 5 2 2 7 7 7 1 I/LWEQ domain ANTH PF07651.11 EDN03303.1 - 3.6e-56 189.9 0.1 3.6e-56 189.9 0.1 3.7 3 2 0 3 3 3 1 ANTH domain DUF4393 PF14337.1 EDN03305.1 - 0.085 12.2 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) COX6A PF02046.10 EDN03308.1 - 6.5e-41 138.8 0.1 7.4e-41 138.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos_2 PF14529.1 EDN03309.1 - 1.7e-06 27.6 0.0 1.1e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN03309.1 - 0.00035 20.5 0.0 0.0028 17.6 0.0 2.4 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 EDN03309.1 - 0.00067 19.5 0.1 0.0022 17.8 0.1 2.0 1 0 0 1 1 1 1 GRF zinc finger Med12 PF09497.5 EDN03310.1 - 2.6e-26 91.3 0.1 7.4e-26 89.9 0.1 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 CIA30 PF08547.7 EDN03311.1 - 1.2e-38 132.4 0.0 2.1e-25 89.4 0.0 2.1 1 1 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Cation_ATPase_N PF00690.21 EDN03311.1 - 0.07 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus SAICAR_synt PF01259.13 EDN03312.1 - 1.1e-85 286.7 0.0 3e-85 285.2 0.0 1.6 1 1 1 2 2 2 2 SAICAR synthetase Apc5 PF12862.2 EDN03313.1 - 8.1e-37 124.9 3.4 1.7e-36 123.9 2.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 SUI1 PF01253.17 EDN03314.1 - 1.9e-29 101.2 5.6 2.5e-29 100.9 3.9 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF520 PF04461.8 EDN03314.1 - 0.19 11.5 3.4 0.23 11.2 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF520) Glyco_hydro_47 PF01532.15 EDN03315.1 - 1.2e-138 462.5 0.1 1.9e-138 461.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Exo_endo_phos_2 PF14529.1 EDN03316.1 - 3.1e-15 55.8 0.0 1.9e-14 53.2 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EDN03316.1 - 2.6e-13 49.8 0.1 5.8e-13 48.6 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 EDN03316.1 - 2.8e-05 24.1 0.0 0.0035 17.2 0.0 2.3 1 1 1 2 2 2 2 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EDN03316.1 - 0.00038 20.2 4.1 0.00038 20.2 2.9 2.6 3 0 0 3 3 3 1 Zinc knuckle DUF837 PF05769.6 EDN03316.1 - 0.088 12.3 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF837) zf-CCHC_4 PF14392.1 EDN03316.1 - 2.8 7.6 11.8 3.6 7.3 2.7 2.6 1 1 1 2 2 2 0 Zinc knuckle SSF PF00474.12 EDN03317.1 - 1.8e-05 23.5 24.9 0.0012 17.5 17.2 2.5 1 1 0 1 1 1 1 Sodium:solute symporter family FCH PF00611.18 EDN03318.1 - 4.8e-16 58.7 1.0 1e-15 57.6 0.1 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 EDN03318.1 - 3.1e-11 43.1 0.0 1.1e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain IFT43 PF15305.1 EDN03318.1 - 0.16 11.9 1.5 0.38 10.7 1.1 1.6 1 0 0 1 1 1 0 Intraflagellar transport protein 43 Ras PF00071.17 EDN03319.1 - 4.2e-55 185.5 0.0 4.8e-55 185.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN03319.1 - 2.9e-17 63.2 0.0 4.2e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN03319.1 - 5.2e-09 35.5 0.0 6.4e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RRM_6 PF14259.1 EDN03320.1 - 4.9e-11 42.4 0.1 1.7e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN03320.1 - 3.2e-10 39.5 0.0 8.2e-10 38.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CMS1 PF14617.1 EDN03321.1 - 2.8e-74 249.3 0.5 3.7e-74 248.9 0.3 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EDN03321.1 - 0.0002 20.8 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase CENP-T PF15511.1 EDN03322.1 - 6.3e-92 308.9 28.0 5.5e-50 170.8 11.4 2.8 2 1 1 3 3 3 2 Centromere kinetochore component CENP-T CENP-S PF15630.1 EDN03322.1 - 3.8e-08 33.3 0.0 7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EDN03322.1 - 6.6e-07 29.3 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDN03322.1 - 0.0006 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DDE_Tnp_IS66 PF03050.9 EDN03322.1 - 0.046 12.9 0.1 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 Transposase IS66 family SURF1 PF02104.10 EDN03323.1 - 7.4e-56 189.3 0.0 9.4e-56 188.9 0.0 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.15 EDN03324.1 - 1.4e-11 44.2 0.0 2.8e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain DUF1703 PF08011.6 EDN03324.1 - 0.59 9.8 2.8 1.1 8.9 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1703) Cytadhesin_P30 PF07271.6 EDN03324.1 - 0.84 8.8 7.3 0.15 11.2 2.4 1.7 2 0 0 2 2 2 0 Cytadhesin P30/P32 DUF2076 PF09849.4 EDN03325.1 - 4.2e-08 33.5 10.0 4.9e-08 33.3 6.9 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EDN03325.1 - 0.0044 16.8 0.4 0.0072 16.2 0.3 1.4 1 0 0 1 1 1 1 CHCH domain VirionAssem_T7 PF11653.3 EDN03325.1 - 0.11 13.2 0.1 0.11 13.2 0.1 1.9 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein HpaP PF09483.5 EDN03325.1 - 8 6.3 17.1 1.9 8.4 7.9 2.0 2 0 0 2 2 2 0 Type III secretion protein (HpaP) DUF605 PF04652.11 EDN03325.1 - 8.1 5.7 10.4 10 5.3 7.2 1.2 1 0 0 1 1 1 0 Vta1 like Sas10_Utp3 PF04000.10 EDN03326.1 - 1.1e-18 67.1 0.2 1.1e-18 67.1 0.1 1.9 2 0 0 2 2 2 1 Sas10/Utp3/C1D family MdcE PF06833.6 EDN03326.1 - 0.2 10.8 0.0 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) DUF4407 PF14362.1 EDN03326.1 - 1 8.2 17.6 0.2 10.5 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Med13_N PF11597.3 EDN03326.1 - 2.4 6.7 9.4 3.3 6.2 6.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal ApbA PF02558.11 EDN03327.1 - 2.3e-06 27.1 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EDN03327.1 - 0.083 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 ThiF family F420_oxidored PF03807.12 EDN03327.1 - 0.15 12.4 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent LIP PF03583.9 EDN03329.1 - 1.2e-65 221.5 0.0 1.8e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 EDN03329.1 - 0.013 15.4 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sec2p PF06428.6 EDN03330.1 - 8e-26 89.8 14.6 8e-26 89.8 10.1 2.0 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p zf-AD PF07776.10 EDN03330.1 - 0.035 14.1 0.1 2.8 8.0 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) PRP21_like_P PF12230.3 EDN03331.1 - 8.1e-48 162.9 21.9 2.2e-46 158.2 15.2 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EDN03331.1 - 1.6e-38 130.1 3.8 5.6e-20 70.7 0.0 2.7 3 0 0 3 3 3 2 Surp module DUF4035 PF13227.1 EDN03331.1 - 0.039 13.3 1.1 0.069 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4035) UPF0547 PF10571.4 EDN03331.1 - 0.12 12.0 0.6 0.22 11.2 0.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF2197 PF09963.4 EDN03331.1 - 1.6 8.7 4.0 3.5 7.6 0.4 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) PBP_sp32 PF07222.7 EDN03331.1 - 1.9 7.5 7.8 2 7.4 1.8 2.2 2 0 0 2 2 2 0 Proacrosin binding protein sp32 PMT PF02366.13 EDN03332.1 - 2.1e-79 266.3 18.7 2.1e-79 266.3 13.0 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EDN03332.1 - 1.8e-50 171.1 0.1 3.1e-50 170.3 0.1 1.3 1 0 0 1 1 1 1 MIR domain zf-DHHC PF01529.15 EDN03334.1 - 6.9e-35 119.9 6.8 1.2e-34 119.2 4.7 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase KorB_C PF06613.6 EDN03334.1 - 0.13 11.7 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 KorB C-terminal beta-barrel domain SET PF00856.23 EDN03335.1 - 0.00028 21.2 10.9 0.00028 21.2 7.5 4.1 3 1 0 3 3 3 1 SET domain Fungal_trans PF04082.13 EDN03336.1 - 6.3e-25 87.5 0.0 9.7e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PMP1_2 PF08114.6 EDN03336.1 - 0.078 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase proteolipid family FGGY_C PF02782.11 EDN03337.1 - 8.6e-72 240.9 0.9 1.4e-71 240.2 0.4 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EDN03337.1 - 7.2e-25 87.7 0.5 7.8e-24 84.3 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.15 EDN03338.1 - 3e-30 105.3 2.4 2.6e-28 99.0 0.0 2.2 1 1 0 2 2 2 2 Major intrinsic protein Pkinase PF00069.20 EDN03340.1 - 1.7e-46 158.4 0.0 3.8e-46 157.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN03340.1 - 2.3e-31 108.7 0.0 4.7e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN03340.1 - 1.1e-06 27.8 0.0 1.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDN03340.1 - 0.0022 17.1 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DAO PF01266.19 EDN03342.1 - 1.8e-48 165.2 0.0 2.6e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDN03342.1 - 6.2e-09 35.1 1.4 2.1e-08 33.4 0.9 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EDN03342.1 - 1e-07 31.3 0.1 1.8e-05 24.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDN03342.1 - 9.9e-05 22.2 0.1 0.00051 19.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EDN03342.1 - 0.00057 19.5 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EDN03342.1 - 0.0018 17.4 0.0 0.44 9.5 0.0 2.6 2 1 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EDN03342.1 - 0.0037 17.2 0.1 0.014 15.3 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EDN03342.1 - 0.0073 15.2 0.1 0.034 13.0 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EDN03342.1 - 0.013 13.9 0.2 0.022 13.2 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 EDN03342.1 - 0.047 12.5 0.3 0.074 11.9 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EDN03342.1 - 0.054 13.9 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN03342.1 - 0.057 12.5 0.1 0.14 11.2 0.1 1.6 1 0 0 1 1 1 0 Thi4 family PAT1 PF09770.4 EDN03343.1 - 3 5.9 14.7 4.3 5.4 10.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glucan_synthase PF02364.10 EDN03345.1 - 0.23 9.2 0.1 0.33 8.7 0.1 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase component MFS_1 PF07690.11 EDN03346.1 - 0.081 11.6 15.1 0.016 13.9 4.2 2.4 2 0 0 2 2 2 0 Major Facilitator Superfamily ATP-sulfurylase PF01747.12 EDN03347.1 - 2e-84 282.2 0.1 2.8e-84 281.7 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EDN03347.1 - 9.9e-57 190.9 0.1 1.5e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EDN03347.1 - 8.4e-53 178.0 0.0 1.4e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AA_permease_2 PF13520.1 EDN03349.1 - 5.9e-53 179.9 43.7 7.5e-53 179.5 30.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN03349.1 - 1.5e-27 96.1 36.9 2e-27 95.6 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease ELF PF03317.8 EDN03349.1 - 0.12 11.6 0.3 0.21 10.8 0.2 1.3 1 0 0 1 1 1 0 ELF protein Glyco_transf_17 PF04724.8 EDN03350.1 - 3.2e-45 154.6 0.2 1.3e-44 152.6 0.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 17 PAPS_reduct PF01507.14 EDN03351.1 - 1.4e-41 142.1 0.0 1.8e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Radical_SAM PF04055.16 EDN03352.1 - 1.2e-12 48.3 0.0 1.8e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily adh_short PF00106.20 EDN03353.1 - 1.9e-09 37.6 0.0 3.5e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN03353.1 - 5.8e-05 22.9 0.0 9.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN03353.1 - 0.14 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 KR domain SlyX PF04102.7 EDN03355.1 - 0.085 13.2 6.9 0.18 12.1 4.8 1.6 1 0 0 1 1 1 0 SlyX GAS PF13851.1 EDN03355.1 - 0.19 10.8 9.6 0.28 10.3 6.6 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Gon7 PF08738.5 EDN03355.1 - 0.65 10.0 4.3 0.73 9.8 2.2 1.8 1 1 0 1 1 1 0 Gon7 family DUF972 PF06156.8 EDN03355.1 - 1.7 8.9 5.8 3.2 8.1 3.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 EDN03355.1 - 4.8 6.7 9.1 3.7 7.1 2.7 2.4 1 1 0 2 2 2 0 Septum formation initiator Methyltrn_RNA_3 PF02598.12 EDN03356.1 - 4.2e-36 124.8 0.0 4.8e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase DeoC PF01791.4 EDN03357.1 - 1.6e-38 132.3 5.7 2e-38 132.0 4.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 EDN03357.1 - 0.00089 18.3 0.7 0.0014 17.6 0.5 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase GRP PF07172.6 EDN03358.1 - 6.1e-05 23.4 8.0 8e-05 23.0 5.5 1.1 1 0 0 1 1 1 1 Glycine rich protein family M_domain PF12938.2 EDN03358.1 - 2.7 7.7 4.9 3.6 7.3 3.4 1.2 1 0 0 1 1 1 0 M domain of GW182 TP_methylase PF00590.15 EDN03359.1 - 3.4e-48 164.1 0.1 6.5e-48 163.2 0.1 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_C PF14823.1 EDN03359.1 - 4.5e-06 25.8 0.0 1.6e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.1 EDN03359.1 - 5e-05 23.5 0.0 9.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding PCI PF01399.22 EDN03360.1 - 4.7e-21 75.0 0.0 1.4e-20 73.5 0.0 1.8 1 0 0 1 1 1 1 PCI domain FSH1 PF03959.8 EDN03361.1 - 2e-58 197.3 0.0 2.7e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EDN03361.1 - 1e-05 25.3 0.0 1.6e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN03361.1 - 1.1e-05 25.3 0.6 0.00019 21.4 0.4 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EDN03361.1 - 0.013 14.7 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase DLH PF01738.13 EDN03361.1 - 0.017 14.4 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Ribosomal_S27e PF01667.12 EDN03363.1 - 2.5e-29 100.5 5.9 3.2e-29 100.2 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EDN03363.1 - 0.0064 16.3 1.2 0.0071 16.1 0.8 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 EDN03363.1 - 0.12 11.8 0.6 0.22 11.0 0.4 1.5 1 0 0 1 1 1 0 CSL zinc finger CDP-OH_P_transf PF01066.16 EDN03365.1 - 9.2e-14 51.5 4.5 9.2e-14 51.5 3.1 3.1 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase GWT1 PF06423.7 EDN03365.1 - 0.00093 19.3 2.3 0.47 10.5 0.1 2.7 1 1 1 2 2 2 2 GWT1 NIPSNAP PF07978.8 EDN03366.1 - 2.7e-29 101.1 0.7 9.1e-29 99.4 0.1 2.1 3 0 0 3 3 3 1 NIPSNAP Pyridox_oxidase PF01243.15 EDN03367.1 - 9.6e-14 51.1 0.0 1.9e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CEP44 PF15007.1 EDN03370.1 - 0.056 13.1 0.2 0.063 12.9 0.2 1.1 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 Peptidase_C65 PF10275.4 EDN03372.1 - 1.5e-42 145.6 0.0 1e-38 133.0 0.0 2.1 1 1 1 2 2 2 2 Peptidase C65 Otubain Chorismate_synt PF01264.16 EDN03372.1 - 0.0071 14.8 0.0 0.021 13.3 0.0 1.6 2 0 0 2 2 2 1 Chorismate synthase PCI PF01399.22 EDN03374.1 - 1.7e-14 54.0 0.1 3.5e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 PCI domain CWC25 PF12542.3 EDN03375.1 - 6.8e-15 55.3 1.1 6.8e-15 55.3 0.8 2.7 2 1 0 2 2 2 1 Pre-mRNA splicing factor Cir_N PF10197.4 EDN03375.1 - 1.6e-12 47.2 14.0 1.6e-12 47.2 9.7 2.4 2 1 1 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Ras PF00071.17 EDN03376.1 - 6.5e-37 126.4 0.0 8.4e-37 126.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN03376.1 - 3.3e-08 34.0 0.0 5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN03376.1 - 2.8e-05 23.4 0.1 4e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDN03376.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RVT_2 PF07727.9 EDN03377.1 - 1.6e-16 60.0 0.6 2.8e-16 59.2 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 EDN03377.1 - 6.8e-08 32.0 0.0 1.5e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 EDN03377.1 - 0.0064 16.2 0.3 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EDN03377.1 - 0.029 13.8 0.1 0.083 12.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) UBN2_2 PF14227.1 EDN03377.1 - 0.036 13.6 0.0 0.093 12.2 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type polyprenyl_synt PF00348.12 EDN03380.1 - 2.3e-43 147.9 0.0 3.2e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EDN03380.1 - 0.0051 16.3 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Rpn3_C PF08375.6 EDN03381.1 - 3.6e-25 88.1 0.2 1.1e-24 86.5 0.1 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EDN03381.1 - 1.8e-19 69.9 0.2 8.2e-19 67.8 0.0 2.1 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EDN03381.1 - 0.017 14.8 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 DASH_Spc34 PF08657.5 EDN03382.1 - 9.8e-69 231.8 0.3 1.5e-68 231.2 0.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Spc34 Uds1 PF15456.1 EDN03382.1 - 0.011 15.7 3.0 0.031 14.2 2.1 1.7 1 0 0 1 1 1 0 Up-regulated During Septation IncA PF04156.9 EDN03382.1 - 0.066 12.8 2.3 0.1 12.1 1.6 1.3 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EDN03382.1 - 0.19 11.2 0.6 9.1 5.8 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF465 PF04325.8 EDN03382.1 - 0.26 11.0 4.4 0.2 11.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF465) TMF_DNA_bd PF12329.3 EDN03382.1 - 0.26 11.1 2.2 1.8 8.4 0.1 2.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding PspB PF06667.7 EDN03382.1 - 0.97 9.4 2.8 7.6 6.5 0.2 2.4 2 0 0 2 2 2 0 Phage shock protein B Mnd1 PF03962.10 EDN03382.1 - 1.7 8.3 4.7 3.3 7.3 3.3 1.4 1 1 0 1 1 1 0 Mnd1 family TFIID_20kDa PF03847.8 EDN03384.1 - 1.1e-09 38.4 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Glyco_hydro_18 PF00704.23 EDN03385.1 - 9.6e-94 314.6 0.9 1.1e-93 314.3 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EDN03385.1 - 1.3e-12 47.4 0.0 2.4e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 LysM domain CorA PF01544.13 EDN03386.1 - 1.3e-15 57.2 0.1 2.1e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Reticulon PF02453.12 EDN03386.1 - 0.032 13.8 0.3 2.1 7.9 0.2 2.2 2 0 0 2 2 2 0 Reticulon TcpE PF12648.2 EDN03386.1 - 0.14 12.2 3.4 0.26 11.4 2.4 1.3 1 0 0 1 1 1 0 TcpE family NAD_binding_6 PF08030.7 EDN03387.1 - 1.5e-21 76.8 0.0 2.9e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EDN03387.1 - 4.5e-21 74.6 0.0 1.1e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EDN03387.1 - 2.6e-17 63.0 8.3 2.6e-17 63.0 5.7 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EDN03387.1 - 8.7e-05 22.5 0.0 0.00022 21.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain eIF2A PF08662.6 EDN03388.1 - 3.4e-83 278.1 0.1 2.4e-82 275.3 0.0 2.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EDN03388.1 - 8.4e-05 22.2 1.2 1.4 8.9 0.1 5.1 5 0 0 5 5 5 1 WD domain, G-beta repeat CDV3 PF15359.1 EDN03388.1 - 0.024 14.7 1.5 0.024 14.7 1.0 3.9 4 1 1 5 5 5 0 Carnitine deficiency-associated protein 3 Cytochrom_D1 PF02239.11 EDN03388.1 - 0.047 11.9 0.0 0.092 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 EDN03388.1 - 0.54 9.6 1.9 11 5.4 0.1 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Acetyltransf_13 PF13880.1 EDN03391.1 - 7.1e-29 99.3 0.0 2.4e-28 97.6 0.0 2.0 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EDN03391.1 - 1.3e-16 59.8 0.4 3.1e-16 58.6 0.3 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Glyoxalase_2 PF12681.2 EDN03392.1 - 1.3e-08 35.3 0.0 2.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain EMG1 PF03587.9 EDN03394.1 - 7.7e-78 260.4 0.0 9.1e-78 260.1 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase UQ_con PF00179.21 EDN03395.1 - 5.4e-51 171.7 0.0 6e-51 171.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDN03395.1 - 0.00011 22.0 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDN03395.1 - 0.0047 16.8 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EDN03395.1 - 0.013 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain XPG_N PF00752.12 EDN03397.1 - 1.2e-30 105.7 0.0 4.2e-30 103.9 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EDN03397.1 - 2.6e-30 104.3 0.1 6.5e-30 103.0 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EDN03397.1 - 1.4e-05 25.2 1.6 3.2e-05 24.1 0.0 2.4 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.6 EDN03397.1 - 0.099 11.5 3.3 0.19 10.6 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) AMP-binding PF00501.23 EDN03398.1 - 3.6e-68 229.8 0.0 5.1e-68 229.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN03398.1 - 1.8e-14 54.4 0.2 3.4e-13 50.3 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Aminotran_3 PF00202.16 EDN03399.1 - 1.6e-23 83.1 0.0 1.9e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Replic_Relax PF13814.1 EDN03399.1 - 0.017 14.9 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 Replication-relaxation adh_short PF00106.20 EDN03400.1 - 1.5e-22 80.2 0.0 6.2e-22 78.2 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN03400.1 - 2.6e-16 60.1 0.0 1.5e-15 57.6 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN03400.1 - 1.1e-10 41.5 0.0 1.6e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN03400.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EDN03400.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2493 PF10686.4 EDN03400.1 - 0.16 11.5 0.4 5.8 6.5 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2493) Polysacc_synt_2 PF02719.10 EDN03400.1 - 0.17 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 EDN03401.1 - 1.1e-14 53.8 30.5 1.1e-14 53.8 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily QCR10 PF09796.4 EDN03401.1 - 0.17 11.5 0.1 0.17 11.5 0.1 3.4 3 1 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) GMC_oxred_C PF05199.8 EDN03403.1 - 4e-28 98.5 0.0 9.2e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EDN03403.1 - 3.6e-27 95.2 0.0 1.6e-26 93.1 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EDN03403.1 - 5.1e-05 22.2 0.0 0.00014 20.8 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Linker_histone PF00538.14 EDN03405.1 - 2.6e-21 75.5 0.8 3.4e-21 75.1 0.1 1.5 2 0 0 2 2 2 1 linker histone H1 and H5 family Ribosomal_L19e PF01280.15 EDN03405.1 - 1.3 8.7 8.3 0.35 10.6 0.4 2.1 2 0 0 2 2 2 0 Ribosomal protein L19e PIP5K PF01504.13 EDN03406.1 - 4.2e-85 284.8 0.6 6e-85 284.3 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase PC_rep PF01851.17 EDN03409.1 - 0.00029 20.8 0.3 0.38 11.0 0.1 3.5 4 0 0 4 4 4 2 Proteasome/cyclosome repeat Fungal_trans_2 PF11951.3 EDN03410.1 - 8.3e-19 67.4 0.0 2e-15 56.2 0.0 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF3357 PF11837.3 EDN03413.1 - 0.12 12.2 0.4 0.2 11.5 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Phosphoesterase PF04185.9 EDN03414.1 - 3.1e-56 191.2 1.7 6.9e-56 190.0 0.3 1.8 2 0 0 2 2 2 1 Phosphoesterase family Sugar_tr PF00083.19 EDN03415.1 - 3.3e-48 164.4 4.2 4e-48 164.1 2.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN03415.1 - 4.3e-13 48.6 1.7 4.3e-13 48.6 1.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Cons_hypoth698 PF03601.9 EDN03415.1 - 0.0027 16.4 2.4 0.0033 16.1 1.6 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 698 CaATP_NAI PF12515.3 EDN03415.1 - 0.11 11.9 0.7 0.26 10.8 0.5 1.6 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain HUN PF08729.5 EDN03418.1 - 4.5e-11 42.4 0.0 9.6e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Phage_lysis PF03245.8 EDN03418.1 - 0.1 12.6 2.1 0.2 11.6 1.5 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein RPAP1_C PF08620.5 EDN03419.1 - 1.2e-27 95.5 0.0 1.7e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 RPAP1-like, C-terminal PDR_CDR PF06422.7 EDN03420.1 - 0.095 12.3 1.5 0.24 11.0 1.0 1.6 1 0 0 1 1 1 0 CDR ABC transporter ABC2_membrane PF01061.19 EDN03421.1 - 6.1e-38 130.0 22.2 6.1e-38 130.0 15.4 1.9 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.7 EDN03421.1 - 2.2e-26 91.5 1.8 5.5e-26 90.2 0.0 2.3 2 0 0 2 2 2 1 CDR ABC transporter ABC_tran PF00005.22 EDN03421.1 - 1.5e-23 83.6 0.0 3e-17 63.2 0.0 3.0 3 0 0 3 3 3 2 ABC transporter AAA_25 PF13481.1 EDN03421.1 - 5e-07 29.3 0.1 1.5e-06 27.7 0.0 1.9 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.2 EDN03421.1 - 1.2e-05 24.5 20.2 2.9e-05 23.2 13.8 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.1 EDN03421.1 - 3.6e-05 23.8 0.0 8.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EDN03421.1 - 3.6e-05 23.8 0.0 0.11 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EDN03421.1 - 3.8e-05 23.1 0.1 0.00059 19.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EDN03421.1 - 0.00027 20.4 0.0 0.00049 19.5 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EDN03421.1 - 0.00091 18.4 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EDN03421.1 - 0.0015 17.8 0.0 0.49 9.5 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EDN03421.1 - 0.0046 17.7 0.0 0.013 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDN03421.1 - 0.0049 17.1 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDN03421.1 - 0.0088 15.9 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDN03421.1 - 0.027 14.6 0.0 0.11 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain Pax2_C PF12403.3 EDN03421.1 - 0.032 13.8 0.4 0.16 11.6 0.2 2.0 2 0 0 2 2 2 0 Paired-box protein 2 C terminal NACHT PF05729.7 EDN03421.1 - 0.035 13.7 0.1 0.08 12.5 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 EDN03421.1 - 0.044 14.1 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EDN03421.1 - 0.09 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EDN03421.1 - 0.12 12.2 0.1 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EDN03421.1 - 0.15 11.0 0.0 1.1 8.2 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain Chs3p PF12271.3 EDN03424.1 - 4.7e-142 472.2 19.3 5.3e-142 472.0 13.4 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit CoatB PF10389.4 EDN03424.1 - 2.9 7.8 8.5 0.22 11.3 1.1 2.6 3 0 0 3 3 3 0 Bacteriophage coat protein B DUF3382 PF11862.3 EDN03424.1 - 3.2 7.7 10.2 0.082 12.8 1.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) Abhydrolase_5 PF12695.2 EDN03425.1 - 1.6e-05 24.7 0.0 4.8e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EDN03425.1 - 7.8e-05 22.0 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EDN03425.1 - 0.00012 21.7 0.3 0.00025 20.6 0.2 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EDN03425.1 - 0.00027 20.8 1.3 0.00044 20.2 0.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EDN03425.1 - 0.0038 16.2 0.0 0.0056 15.6 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 EDN03425.1 - 0.026 13.8 0.1 0.64 9.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_2 PF02230.11 EDN03425.1 - 0.035 13.5 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 EDN03425.1 - 0.041 14.1 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 Thioesterase domain Pex14_N PF04695.8 EDN03425.1 - 0.13 12.3 1.2 0.23 11.5 0.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF915 PF06028.6 EDN03425.1 - 0.15 11.1 0.0 9.3 5.2 0.0 2.9 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) DUF1459 PF07312.6 EDN03425.1 - 0.44 10.5 7.0 6.6 6.7 0.0 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF1459) YCII PF03795.9 EDN03426.1 - 2e-09 37.4 0.0 3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Med25_VWA PF11265.3 EDN03426.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A AMP-binding PF00501.23 EDN03429.1 - 1.1e-37 129.4 0.0 1.7e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN03429.1 - 0.0046 17.8 0.0 0.05 14.5 0.0 2.6 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_M16 PF00675.15 EDN03430.1 - 3.8e-30 104.5 0.0 5e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EDN03431.1 - 2.3e-34 118.6 0.0 3.1e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Abhydrolase_2 PF02230.11 EDN03432.1 - 1.6e-28 99.6 0.0 2.8e-19 69.4 0.0 3.0 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EDN03432.1 - 1.2e-10 41.7 2.2 2.6e-10 40.5 1.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN03432.1 - 2.5e-06 27.3 0.0 8.2e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDN03432.1 - 0.0028 16.8 0.0 0.006 15.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 EDN03432.1 - 0.0072 15.7 0.0 0.015 14.7 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Aminotran_1_2 PF00155.16 EDN03433.1 - 4.5e-34 117.9 0.0 6.2e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Tmemb_18A PF09771.4 EDN03433.1 - 0.0017 18.3 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein 188 Aminotran_5 PF00266.14 EDN03433.1 - 0.0099 14.6 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V PQ-loop PF04193.9 EDN03434.1 - 3.8e-21 74.4 6.6 3.2e-18 65.0 1.2 2.7 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EDN03434.1 - 0.34 10.7 0.1 0.34 10.7 0.1 2.2 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange SH3_1 PF00018.23 EDN03435.1 - 1.9e-05 23.9 0.1 3.9e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Pkinase PF00069.20 EDN03436.1 - 2.8e-48 164.3 0.0 3.6e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN03436.1 - 5.8e-26 91.1 0.0 9.9e-25 87.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L18e PF00828.14 EDN03437.1 - 1.4e-06 28.6 0.1 2.7e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 AATase PF07247.7 EDN03439.1 - 2.6e-10 39.4 0.0 1.2e-09 37.2 0.0 1.9 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EDN03439.1 - 1.5e-06 27.2 0.2 2.6e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 Condensation domain WES_acyltransf PF03007.11 EDN03439.1 - 0.0043 16.6 0.5 0.012 15.1 0.1 1.8 2 0 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Pyr_redox_2 PF07992.9 EDN03440.1 - 1.9e-26 93.2 0.1 5.6e-16 59.0 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN03440.1 - 1.6e-11 44.4 0.0 1.5e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDN03440.1 - 0.0014 18.7 0.6 1.9 8.5 0.1 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDN03440.1 - 0.14 10.6 2.2 0.53 8.6 0.2 2.5 2 1 1 3 3 3 0 HI0933-like protein DUF4211 PF13926.1 EDN03442.1 - 2.6e-43 147.0 0.0 4.1e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) ScpA_ScpB PF02616.9 EDN03442.1 - 0.23 11.0 2.2 0.34 10.4 1.5 1.2 1 0 0 1 1 1 0 ScpA/B protein DUF4449 PF14613.1 EDN03443.1 - 2.6e-59 199.8 0.6 2.6e-59 199.8 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) PTPLA PF04387.9 EDN03444.1 - 1.5e-26 92.7 3.5 1.8e-26 92.5 2.4 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Adaptin_binding PF10199.4 EDN03445.1 - 1.7e-17 63.9 2.8 1.7e-17 63.9 2.0 2.0 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 DUF1241 PF06840.6 EDN03445.1 - 0.022 14.0 0.1 0.049 12.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) LSM PF01423.17 EDN03446.1 - 1.3e-13 50.2 0.4 1.7e-13 49.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain PGP_phosphatase PF09419.5 EDN03447.1 - 2e-41 141.1 0.0 5.9e-40 136.3 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EDN03447.1 - 0.00034 20.2 0.0 0.0007 19.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDN03447.1 - 0.0048 17.3 0.0 2.3 8.6 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Homeobox PF00046.24 EDN03448.1 - 8e-20 70.2 4.0 1.7e-19 69.1 2.8 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EDN03448.1 - 0.00013 21.6 0.4 0.00037 20.1 0.3 1.8 1 0 0 1 1 1 1 Homeobox KN domain MFS_1 PF07690.11 EDN03450.1 - 2.6e-35 121.7 14.5 3.3e-35 121.4 10.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EDN03450.1 - 0.0043 16.8 0.6 0.014 15.1 0.1 2.2 2 0 0 2 2 2 1 MFS_1 like family DUF4118 PF13493.1 EDN03450.1 - 0.052 13.7 0.3 0.052 13.7 0.2 3.5 4 1 0 4 4 4 0 Domain of unknown function (DUF4118) Hydrolase PF00702.21 EDN03451.1 - 7.2e-18 65.7 0.0 9.2e-17 62.1 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EDN03451.1 - 6.8e-15 54.7 0.8 6.8e-15 54.7 0.5 2.2 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EDN03451.1 - 4.7e-14 53.0 0.5 1.1e-12 48.4 0.3 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN03451.1 - 1.5e-10 40.8 0.0 4.6e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EDN03451.1 - 0.00099 18.7 0.1 0.0024 17.5 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NAD_binding_10 PF13460.1 EDN03452.1 - 5e-13 49.4 0.0 6.3e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EDN03452.1 - 0.00013 20.7 0.0 0.00018 20.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EDN03452.1 - 0.00016 21.9 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EDN03452.1 - 0.0002 20.8 0.0 0.0004 19.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EDN03452.1 - 0.001 18.9 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EDN03452.1 - 0.0037 16.2 0.0 0.0076 15.1 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.8 EDN03452.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 EDN03452.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain vWA-TerF-like PF10138.4 EDN03453.1 - 3.4e-05 23.7 0.0 4.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus SRP72 PF08492.7 EDN03455.1 - 4.9e-18 65.2 4.9 4.9e-18 65.2 3.4 2.2 2 0 0 2 2 2 1 SRP72 RNA-binding domain Apc3 PF12895.2 EDN03455.1 - 3.7e-05 23.7 3.3 0.55 10.4 0.1 4.3 3 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EDN03455.1 - 0.00015 21.9 10.4 0.0032 17.7 0.1 5.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDN03455.1 - 0.00086 19.9 12.1 2.2 9.0 0.0 5.7 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDN03455.1 - 0.0027 18.1 13.5 1.5 9.6 0.0 7.8 7 4 3 10 10 9 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDN03455.1 - 0.0077 16.0 2.8 37 4.5 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Dicty_REP PF05086.7 EDN03455.1 - 0.14 9.8 1.9 0.21 9.3 1.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PPR PF01535.15 EDN03455.1 - 0.3 11.1 0.9 27 5.0 0.0 3.9 4 0 0 4 4 4 0 PPR repeat TPR_20 PF14561.1 EDN03455.1 - 0.33 11.0 5.0 1.4 9.0 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDN03455.1 - 0.37 10.7 7.3 16 5.5 0.0 5.1 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 EDN03455.1 - 0.9 10.1 4.5 4.4 8.0 0.1 3.8 4 0 0 4 4 2 0 Tetratricopeptide repeat adh_short PF00106.20 EDN03456.1 - 1.4e-09 38.0 0.1 0.00019 21.4 0.2 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EDN03456.1 - 0.023 14.3 0.1 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 KR domain FAD_binding_1 PF00667.15 EDN03457.1 - 3.8e-17 62.4 0.0 1.1e-10 41.3 0.0 2.3 1 1 1 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.16 EDN03457.1 - 1.5e-09 38.3 0.0 2.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Med20 PF08612.6 EDN03459.1 - 2.9e-93 311.1 0.0 3.6e-93 310.8 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex EF-hand_1 PF00036.27 EDN03460.1 - 3.1e-41 135.5 11.5 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EDN03460.1 - 9.2e-37 125.0 5.9 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EDN03460.1 - 1.5e-34 117.3 11.8 6.8e-16 57.6 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EDN03460.1 - 1.5e-30 102.3 6.8 3.4e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EDN03460.1 - 1.8e-26 90.2 7.7 1.9e-06 26.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EDN03460.1 - 1.2e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EDN03460.1 - 5.1e-10 39.0 1.5 0.00063 19.4 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EDN03460.1 - 1.6e-08 34.5 0.0 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EDN03460.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EDN03460.1 - 5.8e-07 29.3 2.4 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EDN03460.1 - 0.00015 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EDN03460.1 - 0.0004 19.9 0.1 0.064 12.8 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein Tenui_NCP PF04876.7 EDN03460.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EDN03460.1 - 0.0027 17.6 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 EDN03460.1 - 0.0059 16.9 1.4 1.8 8.9 0.0 2.5 1 1 1 2 2 2 2 Toprim-like DUF3349 PF11829.3 EDN03460.1 - 0.025 14.9 0.4 8.4 6.8 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 EDN03460.1 - 0.14 11.8 2.4 0.84 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 EDN03460.1 - 0.28 10.8 4.1 0.59 9.7 0.3 2.3 1 1 1 2 2 2 0 RloB-like protein PB1 PF00564.19 EDN03460.1 - 0.43 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 EDN03461.1 - 1.1e-14 53.7 9.0 2.3e-14 52.8 1.4 3.1 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EDN03461.1 - 2.1e-13 50.2 1.1 2.1e-13 50.2 0.8 2.1 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EDN03461.1 - 0.0072 15.8 6.1 0.079 12.4 0.6 2.3 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF349 PF03993.7 EDN03461.1 - 0.023 14.8 1.9 0.3 11.2 0.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DNA_repr_REX1B PF14966.1 EDN03461.1 - 0.03 14.7 0.9 0.093 13.1 0.1 2.2 2 0 0 2 2 2 0 DNA repair REX1-B KxDL PF10241.4 EDN03461.1 - 0.22 11.4 2.0 6 6.8 0.2 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein Syntaxin_2 PF14523.1 EDN03461.1 - 1.3 9.1 7.0 0.99 9.4 3.0 2.2 2 1 0 2 2 2 0 Syntaxin-like protein SlyX PF04102.7 EDN03461.1 - 3.6 8.0 7.7 6.8 7.1 0.4 3.2 3 1 1 4 4 4 0 SlyX CTD_bind PF04818.8 EDN03462.1 - 4.5e-14 52.4 0.8 8.2e-14 51.6 0.6 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Clathrin_lg_ch PF01086.12 EDN03463.1 - 9.5e-66 221.9 0.6 1.1e-65 221.7 0.4 1.0 1 0 0 1 1 1 1 Clathrin light chain ATP-synt_B PF00430.13 EDN03463.1 - 0.52 10.1 5.7 0.81 9.4 3.9 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Acyl_transf_3 PF01757.17 EDN03464.1 - 1.7e-14 53.4 22.5 2.1e-14 53.1 15.6 1.1 1 0 0 1 1 1 1 Acyltransferase family Acyl_transf_3 PF01757.17 EDN03465.1 - 1.5e-23 83.1 45.4 8e-14 51.2 3.2 2.9 1 1 1 2 2 2 2 Acyltransferase family RseC_MucC PF04246.7 EDN03465.1 - 5.8 6.4 6.4 4.4 6.8 0.6 2.8 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Mannosyl_trans3 PF11051.3 EDN03466.1 - 1.1e-73 247.9 0.0 5e-73 245.7 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EDN03466.1 - 0.17 11.1 0.1 0.34 10.2 0.1 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 8 CDC37_N PF03234.9 EDN03467.1 - 8.4e-60 202.1 6.3 1.8e-59 201.0 4.3 1.6 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EDN03467.1 - 5.1e-45 153.0 0.1 1.4e-44 151.6 0.0 1.7 1 1 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EDN03467.1 - 7.3e-09 35.3 2.4 3.3e-08 33.2 0.0 3.0 2 1 0 2 2 2 1 Cdc37 C terminal domain DUF3552 PF12072.3 EDN03467.1 - 0.0045 16.2 3.9 0.0045 16.2 2.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) MecA_N PF05223.6 EDN03467.1 - 0.032 14.2 2.4 0.068 13.2 0.7 2.2 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain DUF4407 PF14362.1 EDN03467.1 - 2.2 7.1 4.4 0.53 9.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ABC_tran PF00005.22 EDN03468.1 - 7.2e-18 65.2 0.0 1.7e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EDN03468.1 - 0.0012 18.1 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EDN03468.1 - 0.01 14.4 0.1 0.013 14.0 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class SbcCD_C PF13558.1 EDN03468.1 - 0.012 15.4 3.3 0.038 13.8 0.6 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EDN03468.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Nucleoside_tran PF01733.13 EDN03469.1 - 1.3e-31 109.9 18.7 3.5e-24 85.5 1.6 2.7 3 0 0 3 3 3 2 Nucleoside transporter Fungal_trans PF04082.13 EDN03470.1 - 3.9e-06 25.9 0.8 3.9e-06 25.9 0.6 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3635 PF12330.3 EDN03471.1 - 4e-07 30.0 0.5 1e-06 28.7 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3635) DUF1814 PF08843.6 EDN03473.1 - 0.00038 20.3 0.0 0.00042 20.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) DUF2204 PF09970.4 EDN03473.1 - 0.0055 16.2 0.0 0.0066 15.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) DUF2404 PF10296.4 EDN03474.1 - 0.00012 22.1 0.0 0.00026 21.0 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF3824 PF12868.2 EDN03474.1 - 0.079 13.8 0.6 0.13 13.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF1682 PF07946.9 EDN03475.1 - 1.1e-115 385.8 0.0 1.3e-115 385.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) COX7a PF02238.10 EDN03476.1 - 0.033 13.9 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa PPR_3 PF13812.1 EDN03477.1 - 9.8e-05 22.3 0.0 0.02 15.1 0.0 4.2 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EDN03477.1 - 0.00081 19.3 0.0 0.0094 15.9 0.0 2.7 3 0 0 3 3 3 1 PPR repeat family PPR PF01535.15 EDN03477.1 - 0.003 17.4 0.0 14 5.9 0.0 4.3 4 0 0 4 4 4 2 PPR repeat Ins_P5_2-kin PF06090.7 EDN03478.1 - 5.6e-73 245.6 0.0 7.2e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DDE_1 PF03184.14 EDN03479.1 - 6.8e-37 126.7 0.0 1.2e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN03479.1 - 1.9e-05 24.3 2.4 8.1e-05 22.3 0.0 3.0 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain PFL PF02901.10 EDN03479.1 - 0.018 13.4 2.4 0.021 13.2 1.0 1.5 1 1 0 1 1 1 0 Pyruvate formate lyase Nitroreductase PF00881.19 EDN03481.1 - 1.7e-15 57.2 0.0 2.1e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family YEATS PF03366.11 EDN03482.1 - 7.2e-36 121.7 1.1 1.2e-35 121.1 0.7 1.3 1 0 0 1 1 1 1 YEATS family Synaptobrevin PF00957.16 EDN03482.1 - 0.16 11.5 0.5 0.28 10.7 0.3 1.3 1 0 0 1 1 1 0 Synaptobrevin NAD_binding_10 PF13460.1 EDN03483.1 - 4.7e-12 46.3 0.0 8.8e-11 42.1 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDN03483.1 - 1.7e-07 30.9 0.0 2.5e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EDN03483.1 - 1.8e-05 24.7 0.0 0.0001 22.3 0.0 2.1 2 1 1 3 3 3 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EDN03483.1 - 2e-05 23.4 0.0 6.8e-05 21.6 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EDN03483.1 - 0.022 13.7 0.1 2.3 7.0 0.0 2.4 2 1 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.12 EDN03483.1 - 0.027 13.3 0.0 0.091 11.6 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.5 EDN03483.1 - 0.074 12.7 0.0 0.83 9.2 0.0 2.1 2 0 0 2 2 2 0 KR domain SYF2 PF08231.7 EDN03484.1 - 1e-41 142.5 14.7 1e-41 142.5 10.2 2.3 2 1 0 2 2 2 1 SYF2 splicing factor CAF-1_p150 PF11600.3 EDN03484.1 - 0.88 8.9 19.6 0.72 9.1 9.8 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF607 PF04678.8 EDN03484.1 - 1.6 8.5 6.8 0.64 9.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF607 DUF4266 PF14086.1 EDN03486.1 - 0.45 11.0 7.2 1 9.8 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) TPR_12 PF13424.1 EDN03487.1 - 0.03 14.2 6.9 0.048 13.5 0.1 3.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDN03487.1 - 3.5 8.5 5.6 42 5.1 0.1 4.6 4 2 2 6 6 6 0 Tetratricopeptide repeat Ribosomal_L12 PF00542.14 EDN03488.1 - 2.4e-18 65.9 5.4 1.6e-17 63.2 3.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Dermcidin PF15291.1 EDN03488.1 - 0.028 14.6 0.9 0.06 13.5 0.6 1.6 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide Ribosomal_60s PF00428.14 EDN03488.1 - 1 9.7 10.2 0.091 13.1 3.0 2.2 1 1 1 2 2 2 0 60s Acidic ribosomal protein Cpn60_TCP1 PF00118.19 EDN03490.1 - 4.4e-32 111.3 0.7 5.2e-32 111.1 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M48 PF01435.13 EDN03491.1 - 4.8e-32 111.3 0.0 5.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 ACT_6 PF13740.1 EDN03491.1 - 0.15 11.7 0.7 0.4 10.4 0.3 1.8 1 1 1 2 2 2 0 ACT domain FAD_binding_4 PF01565.18 EDN03494.1 - 8.3e-16 57.7 1.7 1.9e-15 56.5 0.5 2.1 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.7 EDN03494.1 - 2.1e-08 33.9 0.1 4.2e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like E1_dh PF00676.15 EDN03495.1 - 1.2e-112 375.5 0.1 1.4e-112 375.2 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EDN03495.1 - 6.7e-05 21.9 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase MR_MLE_C PF13378.1 EDN03495.1 - 0.0092 15.9 0.0 3.8 7.5 0.0 2.4 2 0 0 2 2 2 2 Enolase C-terminal domain-like TPP_enzyme_C PF02775.16 EDN03495.1 - 0.043 13.4 0.9 0.1 12.1 0.6 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain GRDA PF04723.9 EDN03496.1 - 0.023 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A Macoilin PF09726.4 EDN03496.1 - 1.3 7.2 17.5 1.6 6.9 12.1 1.1 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 EDN03496.1 - 6.7 6.4 32.4 11 5.7 22.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit S4 PF01479.20 EDN03497.1 - 2.1e-14 52.6 0.0 3.8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EDN03497.1 - 0.046 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 S4 domain SSP160 PF06933.6 EDN03497.1 - 3.6 5.4 10.8 5.1 4.9 7.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CTP_transf_1 PF01148.15 EDN03500.1 - 2.3e-58 197.9 4.0 2.6e-58 197.6 2.8 1.0 1 0 0 1 1 1 1 Cytidylyltransferase family Cyclin_N PF00134.18 EDN03501.1 - 3.9e-11 42.6 0.0 2.7e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.14 EDN03501.1 - 0.14 12.0 0.9 0.88 9.4 0.2 2.4 2 1 0 2 2 2 0 Transcription factor TFIIB repeat zf-C2H2 PF00096.21 EDN03502.1 - 4e-14 52.0 52.6 0.026 14.8 0.2 10.1 9 1 1 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN03502.1 - 8.4e-10 38.2 48.1 0.064 13.6 0.1 9.8 8 2 2 10 10 10 6 C2H2-type zinc finger WAC_Acf1_DNA_bd PF10537.4 EDN03502.1 - 3e-05 24.1 2.7 0.011 15.8 0.1 2.8 2 0 0 2 2 2 2 ATP-utilising chromatin assembly and remodelling N-terminal zf-C2H2_jaz PF12171.3 EDN03502.1 - 9e-05 22.4 45.9 0.23 11.6 0.3 8.7 7 1 1 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDN03502.1 - 0.0039 17.3 34.6 0.37 11.0 0.1 7.3 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 EDN03502.1 - 0.035 14.3 2.0 0.035 14.3 1.4 4.8 5 1 1 6 6 6 0 C2H2-type zinc-finger domain GST_N_3 PF13417.1 EDN03503.1 - 1.9e-16 60.0 0.1 4e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDN03503.1 - 5.3e-10 39.1 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDN03503.1 - 2.1e-06 27.4 0.0 3.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EDN03503.1 - 2.3e-06 27.4 0.0 4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EDN03503.1 - 0.00048 20.2 0.0 0.00092 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EDN03503.1 - 0.007 16.8 0.0 0.012 16.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Arm PF00514.18 EDN03504.1 - 1e-06 28.3 9.7 0.9 9.4 0.1 8.2 10 1 0 10 10 10 4 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EDN03504.1 - 0.0062 16.5 1.2 4 7.7 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 EDN03504.1 - 0.031 14.7 6.0 3.8 8.1 0.0 5.7 6 1 1 7 7 7 0 HEAT-like repeat Cyclin PF08613.6 EDN03505.1 - 7e-16 58.9 0.2 1.3e-15 58.1 0.0 1.5 2 0 0 2 2 2 1 Cyclin BC10 PF06726.7 EDN03506.1 - 4.9e-16 58.5 10.0 7.2e-16 57.9 6.9 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Glyoxalase_2 PF12681.2 EDN03508.1 - 6.8e-09 36.3 0.1 8.5e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EDN03508.1 - 0.0049 16.8 0.2 0.017 15.1 0.2 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Chs3p PF12271.3 EDN03509.1 - 1.1e-115 385.6 2.0 1.4e-115 385.3 1.4 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF423 PF04241.10 EDN03509.1 - 2.3 8.2 8.8 0.45 10.4 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF423) UCH PF00443.24 EDN03511.1 - 4.2e-23 81.8 0.2 1.1e-21 77.1 0.2 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDN03511.1 - 2.2e-08 33.9 0.1 0.0011 18.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase HNOBA PF07701.9 EDN03511.1 - 0.046 12.9 0.0 0.062 12.5 0.0 1.2 1 0 0 1 1 1 0 Heme NO binding associated zf-C3HC4_2 PF13923.1 EDN03512.1 - 6.7e-09 35.6 9.3 1.1e-08 34.9 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN03512.1 - 7.6e-08 31.8 8.1 1.4e-07 31.0 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN03512.1 - 6.7e-07 29.0 7.7 1.1e-06 28.3 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDN03512.1 - 1.7e-06 27.6 5.5 2.9e-06 26.8 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDN03512.1 - 4.6e-06 26.4 6.3 3e-05 23.8 4.8 1.9 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EDN03512.1 - 3.3e-05 23.4 5.6 6.6e-05 22.5 3.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EDN03512.1 - 0.029 14.0 5.6 0.031 13.9 3.0 1.8 1 1 0 1 1 1 0 RING-type zinc-finger PucR PF07905.6 EDN03512.1 - 0.051 13.1 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family TerY-C PF15616.1 EDN03512.1 - 0.29 11.0 1.7 0.28 11.1 0.2 1.6 2 0 0 2 2 1 0 TerY-C metal binding domain FYVE PF01363.16 EDN03512.1 - 0.44 10.4 2.5 1.3 8.9 1.7 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-rbx1 PF12678.2 EDN03512.1 - 1.3 9.1 5.0 5.2 7.2 3.5 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger ERG4_ERG24 PF01222.12 EDN03513.1 - 1.6e-141 471.7 17.4 1.9e-141 471.5 12.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Methyltransf_23 PF13489.1 EDN03514.1 - 1.4e-19 70.3 0.0 9.1e-19 67.7 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN03514.1 - 5.2e-09 36.6 0.0 2.6e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN03514.1 - 1.2e-06 28.9 0.0 0.017 15.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EDN03514.1 - 7.6e-06 25.9 0.0 3.1e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN03514.1 - 1.1e-05 25.8 0.0 0.064 13.7 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 EDN03514.1 - 0.00015 21.3 0.0 0.009 15.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain DUF3606 PF12244.3 EDN03514.1 - 0.0019 17.7 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3606) FtsJ PF01728.14 EDN03514.1 - 0.0059 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EDN03514.1 - 0.0067 16.7 0.0 0.023 15.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 EDN03514.1 - 0.021 14.3 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.13 EDN03514.1 - 0.039 13.0 0.0 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EDN03514.1 - 0.072 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EDN03514.1 - 0.073 12.4 0.0 0.52 9.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EDN03514.1 - 0.12 11.3 0.0 0.45 9.5 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Cauli_VI PF01693.11 EDN03515.1 - 1.4e-32 111.4 5.1 4.4e-17 61.8 0.1 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EDN03515.1 - 1.9e-29 102.6 0.0 3.6e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 RNase H Pkinase PF00069.20 EDN03516.1 - 7e-37 126.9 0.0 1.2e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN03516.1 - 1.5e-23 83.2 0.0 2.1e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN03516.1 - 8.6e-06 24.9 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN03516.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FMN_dh PF01070.13 EDN03518.1 - 7.5e-58 196.0 2.6 4.4e-48 163.9 1.2 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EDN03518.1 - 1.6e-22 79.1 0.0 3.4e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EDN03518.1 - 1e-06 27.9 0.1 1.5e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EDN03518.1 - 2.6e-06 26.5 0.2 3.2e-05 23.0 0.1 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ATP11 PF06644.6 EDN03518.1 - 0.00061 19.3 0.0 0.00087 18.8 0.0 1.2 1 0 0 1 1 1 1 ATP11 protein His_biosynth PF00977.16 EDN03518.1 - 0.015 14.5 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 EDN03518.1 - 0.042 12.9 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DHO_dh PF01180.16 EDN03518.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF202 PF02656.10 EDN03519.1 - 0.0019 18.3 2.2 0.0052 16.9 1.5 1.7 1 1 1 2 2 2 2 Domain of unknown function (DUF202) 6PF2K PF01591.13 EDN03520.1 - 2.5e-68 229.4 0.0 5.4e-47 159.7 0.0 2.1 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EDN03520.1 - 3.7e-27 95.3 0.0 6.6e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EDN03520.1 - 2.6e-06 27.3 0.0 0.083 12.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EDN03520.1 - 0.00073 20.3 0.1 0.0031 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EDN03520.1 - 0.0024 17.0 0.1 1.6 7.7 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin KTI12 PF08433.5 EDN03520.1 - 0.041 13.0 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 VTC PF09359.5 EDN03521.1 - 5.9e-88 294.5 0.1 9.3e-88 293.9 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EDN03521.1 - 1.5e-21 77.4 10.9 8.6e-15 55.2 1.5 2.9 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EDN03521.1 - 7.1e-08 32.5 6.5 7.1e-08 32.5 4.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CYTH PF01928.16 EDN03521.1 - 5.4e-05 22.9 0.1 0.00013 21.6 0.1 1.6 1 0 0 1 1 1 1 CYTH domain CBFD_NFYB_HMF PF00808.18 EDN03522.1 - 4e-06 26.7 0.2 4.9e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.1 EDN03522.1 - 0.019 14.9 0.1 0.05 13.5 0.1 1.6 1 1 0 1 1 1 0 Centromere kinetochore component W AAA_32 PF13654.1 EDN03522.1 - 0.029 13.0 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EDN03524.1 - 5.5e-18 64.7 22.5 1.9e-17 63.0 4.8 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily WD40 PF00400.27 EDN03527.1 - 2.3e-19 68.4 0.9 8.5e-08 31.8 0.0 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat DUF3639 PF12341.3 EDN03527.1 - 1e-11 44.6 2.7 1e-11 44.6 1.9 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 EDN03527.1 - 2.3e-05 23.3 0.0 9.3e-05 21.3 0.0 1.9 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 EDN03527.1 - 0.00018 21.2 0.0 0.098 12.3 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DNA_pol_alpha_N PF12254.3 EDN03527.1 - 0.015 15.1 4.0 0.042 13.6 2.7 1.8 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal IKI3 PF04762.7 EDN03527.1 - 0.42 8.3 0.2 0.88 7.2 0.0 1.7 2 0 0 2 2 2 0 IKI3 family PQQ_3 PF13570.1 EDN03527.1 - 2.3 8.5 5.6 22 5.4 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain p450 PF00067.17 EDN03528.1 - 2e-12 46.4 0.0 3.7e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Amidase PF01425.16 EDN03530.1 - 7e-47 160.2 0.1 8.4e-47 160.0 0.1 1.1 1 0 0 1 1 1 1 Amidase RNA12 PF10443.4 EDN03531.1 - 3.6e-56 190.4 0.0 4.4e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 RNA12 protein Glu_synthase PF01645.12 EDN03532.1 - 5.7e-159 528.9 0.0 9.9e-159 528.1 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.9 EDN03532.1 - 2.2e-120 401.2 0.0 1.4e-119 398.6 0.0 2.0 2 0 0 2 2 2 1 Glutamate synthase central domain GATase_2 PF00310.16 EDN03532.1 - 3.6e-113 377.9 0.0 5.3e-113 377.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GXGXG PF01493.14 EDN03532.1 - 2.1e-65 219.5 1.0 3.9e-65 218.6 0.7 1.4 1 0 0 1 1 1 1 GXGXG motif FMN_dh PF01070.13 EDN03532.1 - 0.081 11.7 0.7 0.41 9.4 0.4 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase HSP70 PF00012.15 EDN03533.1 - 2.5e-113 379.1 1.1 4.5e-113 378.2 0.3 1.5 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EDN03533.1 - 4e-11 42.0 0.0 6.2e-11 41.4 0.0 1.3 1 1 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EDN03533.1 - 0.0077 15.3 0.0 0.016 14.2 0.0 1.5 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase StbA PF06406.6 EDN03533.1 - 0.096 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 StbA protein DUF4582 PF15189.1 EDN03533.1 - 0.1 11.8 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) CHZ PF09649.5 EDN03534.1 - 4.1e-17 61.1 0.9 4.1e-17 61.1 0.7 2.1 2 0 0 2 2 2 1 Histone chaperone domain CHZ EBV-NA3 PF05009.7 EDN03534.1 - 0.07 12.3 3.9 0.49 9.5 1.3 2.1 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) SNARE PF05739.14 EDN03536.1 - 8.7e-09 34.9 1.7 1.2e-08 34.5 1.2 1.2 1 0 0 1 1 1 1 SNARE domain Apc15p PF05841.6 EDN03537.1 - 2.5e-29 102.5 2.5 2.5e-29 102.5 1.7 2.4 2 0 0 2 2 2 1 Apc15p protein Mito_carr PF00153.22 EDN03538.1 - 3.6e-06 26.5 0.2 0.00012 21.7 0.0 2.5 2 1 0 2 2 2 2 Mitochondrial carrier protein Coprogen_oxidas PF01218.13 EDN03539.1 - 4.8e-121 402.8 0.2 1.1e-119 398.3 0.0 2.6 2 1 0 2 2 2 1 Coproporphyrinogen III oxidase HOOK PF05622.7 EDN03540.1 - 1.6e-27 95.7 51.8 2.2e-27 95.2 35.9 1.2 1 0 0 1 1 1 1 HOOK protein IncA PF04156.9 EDN03540.1 - 0.0027 17.3 7.8 0.0027 17.3 5.4 5.8 1 1 5 6 6 6 2 IncA protein Fib_alpha PF08702.5 EDN03540.1 - 0.0067 16.5 7.1 0.0067 16.5 4.9 6.4 3 2 4 7 7 7 2 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.4 EDN03540.1 - 0.0081 16.0 14.5 0.0081 16.0 10.1 6.7 3 2 3 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EDN03540.1 - 0.056 12.6 20.5 0.037 13.2 3.0 3.6 1 1 2 4 4 4 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EDN03540.1 - 0.079 12.7 0.1 0.079 12.7 0.0 6.0 5 2 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EDN03540.1 - 1.4 9.2 37.0 0.19 12.0 1.6 7.0 5 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein FliJ PF02050.11 EDN03540.1 - 3.6 7.6 60.2 0.023 14.7 7.6 6.6 3 3 2 6 6 6 0 Flagellar FliJ protein Spc7 PF08317.6 EDN03540.1 - 9.2 4.8 62.9 0.0069 15.0 8.6 4.3 2 1 2 5 5 5 0 Spc7 kinetochore protein Myb_DNA-binding PF00249.26 EDN03544.1 - 0.00031 20.7 0.1 0.00066 19.6 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF573 PF04504.9 EDN03544.1 - 0.00088 19.5 0.8 0.0025 18.0 0.6 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF573 Myb_DNA-bind_6 PF13921.1 EDN03544.1 - 0.0021 18.1 1.0 0.0051 16.8 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDN03544.1 - 0.019 15.0 2.3 0.28 11.3 1.6 2.3 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF3505 PF12013.3 EDN03545.1 - 3.1e-37 127.1 5.1 3.1e-37 127.1 3.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) DEAD PF00270.24 EDN03545.1 - 1.6e-15 56.9 0.0 5.5e-15 55.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN03545.1 - 3.5e-15 55.6 0.1 1e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN03545.1 - 3.3e-06 27.0 0.9 7.8e-05 22.5 0.0 3.4 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DDE_Tnp_1_7 PF13843.1 EDN03547.1 - 0.005 15.9 0.0 0.005 15.9 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 Ste5 PF11610.3 EDN03550.1 - 0.00011 21.6 11.7 1.3 8.6 0.1 4.8 5 0 0 5 5 5 3 Scaffold protein Ste5-Fus5 binding region CaATP_NAI PF12515.3 EDN03550.1 - 0.047 13.2 2.9 39 3.8 0.0 3.8 3 0 0 3 3 3 0 Ca2+-ATPase N terminal autoinhibitory domain Helicase_C PF00271.26 EDN03551.1 - 5.4e-12 45.4 0.0 1.3e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DDE_Tnp_1_7 PF13843.1 EDN03552.1 - 0.005 15.9 0.0 0.005 15.9 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 zf-CCHC PF00098.18 EDN03553.1 - 0.0002 21.1 2.4 0.00033 20.4 1.7 1.4 1 0 0 1 1 1 1 Zinc knuckle UBN2 PF14223.1 EDN03553.1 - 0.00021 21.0 0.9 0.00042 20.0 0.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type RVT_2 PF07727.9 EDN03554.1 - 3.2e-52 176.9 0.0 4.7e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN03554.1 - 5.8e-16 58.6 0.1 2.2e-15 56.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DUF4219 PF13961.1 EDN03554.1 - 0.023 14.1 1.9 0.05 13.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) gag_pre-integrs PF13976.1 EDN03554.1 - 0.024 14.2 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain Pkinase PF00069.20 EDN03555.1 - 3e-09 36.4 0.0 6.2e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN03555.1 - 2.7e-06 27.2 0.0 2.7e-06 27.2 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EDN03555.1 - 0.00026 20.1 0.3 0.00057 19.0 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family HSDR_N_2 PF13588.1 EDN03555.1 - 0.0052 16.5 0.0 0.71 9.6 0.0 2.4 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) Pkinase_Tyr PF07714.12 EDN03555.1 - 0.0063 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EDN03555.1 - 0.057 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L38e PF01781.13 EDN03555.1 - 0.11 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L38e protein family Chromo PF00385.19 EDN03556.1 - 7.9e-05 22.2 0.5 0.00016 21.2 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EDN03557.1 - 9.3e-11 41.8 0.0 5.5e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EDN03557.1 - 4e-08 32.7 0.0 9.2e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_3 PF14244.1 EDN03557.1 - 0.007 15.9 0.6 0.013 15.0 0.4 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EDN03557.1 - 0.012 15.0 0.5 0.035 13.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) UBN2_2 PF14227.1 EDN03557.1 - 0.043 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RVT_2 PF07727.9 EDN03558.1 - 4.2e-59 199.4 0.0 2.1e-46 157.9 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) PBP_sp32 PF07222.7 EDN03559.1 - 6.6 5.8 7.2 12 4.9 5.0 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DDE_1 PF03184.14 EDN03560.1 - 2.4e-05 23.5 0.0 0.00012 21.2 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN03560.1 - 0.012 15.4 0.1 0.043 13.6 0.0 2.1 2 1 0 2 2 2 0 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN03560.1 - 0.046 13.2 0.4 0.084 12.4 0.0 1.6 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_8 PF02954.14 EDN03560.1 - 0.064 12.8 2.0 0.53 9.8 0.0 2.8 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family RVT_1 PF00078.22 EDN03561.1 - 5.5e-20 71.6 0.0 8.5e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN03562.1 - 2.1e-15 56.3 0.0 4.6e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EDN03562.1 - 2.1e-05 23.9 0.0 3.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 EDN03562.1 - 0.00025 21.0 0.0 0.00042 20.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.19 EDN03564.1 - 5.9e-15 55.7 0.0 9.7e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN03564.1 - 0.11 12.2 0.1 0.37 10.5 0.1 1.9 1 1 0 1 1 1 0 Reverse transcriptase-like DDE_3 PF13358.1 EDN03565.1 - 2.9e-05 23.8 0.1 4.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EDN03566.1 - 7.3e-27 93.2 0.0 1.2e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EDN03566.1 - 0.00047 20.9 0.0 0.001 19.8 0.0 1.7 1 1 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 EDN03566.1 - 0.00092 19.3 0.0 0.0016 18.6 0.0 1.4 1 1 0 1 1 1 1 Winged helix-turn helix HTH_21 PF13276.1 EDN03566.1 - 0.0025 17.7 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 HTH-like domain HTH_23 PF13384.1 EDN03566.1 - 0.0091 15.6 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.1 EDN03566.1 - 0.1 12.1 0.1 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_10 PF04967.7 EDN03566.1 - 0.15 11.6 0.1 2.9 7.5 0.0 2.6 2 2 0 2 2 2 0 HTH DNA binding domain DDE_1 PF03184.14 EDN03567.1 - 2.4e-11 43.2 0.0 3.7e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Lyase_1 PF00206.15 EDN03568.1 - 1.5e-22 80.1 0.1 2.4e-22 79.5 0.1 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EDN03568.1 - 1.3e-14 53.9 0.0 5.9e-14 51.8 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus RNase_H PF00075.19 EDN03569.1 - 1.1e-07 32.1 0.0 2.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 RNase H Baculo_PEP_C PF04513.7 EDN03570.1 - 0.11 12.3 0.8 0.78 9.5 0.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EXS PF03124.9 EDN03571.1 - 1.1e-68 231.7 16.5 4.4e-59 200.2 7.0 2.1 1 1 1 2 2 2 2 EXS family SPX PF03105.14 EDN03571.1 - 5.1e-68 229.8 0.0 1.1e-67 228.7 0.0 1.5 2 0 0 2 2 2 1 SPX domain DUF3332 PF11810.3 EDN03571.1 - 0.19 11.3 0.1 18 4.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3332) LKAAEAR PF15478.1 EDN03571.1 - 0.43 10.8 3.9 8 6.7 0.3 2.4 2 0 0 2 2 2 0 Family of unknown function with LKAAEAR motif OEP PF02321.13 EDN03571.1 - 1.3 8.5 4.3 5.8 6.4 0.1 2.7 3 0 0 3 3 3 0 Outer membrane efflux protein Abhydrolase_1 PF00561.15 EDN03572.1 - 3.3e-46 157.7 0.1 4.8e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDN03572.1 - 6.1e-15 55.7 1.1 4e-14 53.0 0.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN03572.1 - 0.00016 21.4 0.1 0.16 11.7 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EDN03572.1 - 0.016 15.0 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein DUF2424 PF10340.4 EDN03572.1 - 0.078 11.5 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Ank_5 PF13857.1 EDN03575.1 - 4.1e-18 64.9 0.0 5.8e-13 48.6 0.0 5.1 3 2 2 5 5 5 1 Ankyrin repeats (many copies) VPS9 PF02204.13 EDN03575.1 - 2e-17 63.1 0.1 4.9e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 EDN03575.1 - 3.2e-11 43.4 0.0 9.4e-07 29.0 0.0 3.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EDN03575.1 - 9.7e-09 34.6 0.0 0.055 13.7 0.0 6.4 7 0 0 7 7 7 1 Ankyrin repeat PX PF00787.19 EDN03575.1 - 4.4e-07 29.6 0.2 1.2e-06 28.2 0.1 1.8 1 0 0 1 1 1 1 PX domain Ank_4 PF13637.1 EDN03575.1 - 1.1e-06 28.9 0.0 0.055 13.9 0.0 4.7 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.25 EDN03575.1 - 3.1e-06 26.6 0.1 0.029 14.1 0.0 5.0 4 1 0 4 4 4 1 Ankyrin repeat HisKA_3 PF07730.8 EDN03575.1 - 0.024 14.9 2.0 0.23 11.8 0.8 3.1 3 0 0 3 3 3 0 Histidine kinase Ribosomal_S11 PF00411.14 EDN03577.1 - 6.7e-10 39.1 0.0 1.1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.10 EDN03578.1 - 1.1e-32 113.0 0.1 2.5e-32 111.9 0.0 1.7 2 0 0 2 2 2 1 Tim44-like domain IGF2_C PF08365.6 EDN03578.1 - 0.047 13.4 0.2 0.16 11.7 0.1 2.0 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide XPC-binding PF09280.6 EDN03579.1 - 0.0023 17.3 6.8 0.0038 16.6 1.3 2.4 2 0 0 2 2 2 1 XPC-binding domain Collar PF07484.7 EDN03579.1 - 0.022 14.5 0.4 0.81 9.5 0.1 2.3 2 0 0 2 2 2 0 Phage Tail Collar Domain DUF3070 PF11270.3 EDN03579.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3070) RIC1 PF07064.8 EDN03580.1 - 3.4e-47 161.0 0.0 6.9e-25 87.9 0.0 3.3 1 1 2 3 3 3 3 RIC1 PUA PF01472.15 EDN03581.1 - 1.6e-13 50.2 0.5 3.2e-13 49.1 0.3 1.6 1 1 0 1 1 1 1 PUA domain YchF-GTPase_C PF06071.8 EDN03582.1 - 1.9e-33 114.0 0.3 4.1e-33 113.0 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EDN03582.1 - 5.4e-13 48.9 0.0 9.8e-13 48.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDN03582.1 - 0.0015 17.8 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EDN03582.1 - 0.021 14.6 0.1 0.076 12.8 0.1 2.0 1 1 0 1 1 1 0 TGS domain MobB PF03205.9 EDN03582.1 - 0.043 13.5 0.7 2.7 7.6 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PPAK PF02818.10 EDN03582.1 - 0.046 13.6 2.3 0.16 11.9 1.6 2.0 1 0 0 1 1 1 0 PPAK motif CBM_X2 PF03442.9 EDN03582.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain X2 GFA PF04828.9 EDN03584.1 - 0.0039 17.1 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CHCH PF06747.8 EDN03585.1 - 0.00095 19.0 0.1 0.0014 18.4 0.1 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EDN03585.1 - 0.031 14.2 0.7 0.069 13.2 0.6 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 EDN03585.1 - 0.081 12.9 2.3 0.72 9.9 0.1 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) NPR3 PF03666.8 EDN03586.1 - 9.4e-103 344.1 0.8 3.1e-58 197.4 0.2 4.0 3 1 1 4 4 4 2 Nitrogen Permease regulator of amino acid transport activity 3 Thioesterase PF00975.15 EDN03587.1 - 0.031 14.4 0.0 0.037 14.2 0.0 1.3 1 1 0 1 1 1 0 Thioesterase domain AMP-binding PF00501.23 EDN03588.1 - 5.3e-47 160.1 0.0 3.3e-46 157.5 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme RVT_2 PF07727.9 EDN03589.1 - 3.1e-41 140.9 0.0 5e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN03589.1 - 4.8e-16 58.9 0.1 1.6e-15 57.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EDN03589.1 - 0.018 14.6 0.0 0.048 13.2 0.0 1.7 1 0 0 1 1 1 0 GAG-pre-integrase domain La PF05383.12 EDN03590.1 - 1.6e-17 63.0 0.2 3.6e-17 61.9 0.2 1.6 1 0 0 1 1 1 1 La domain Band_7 PF01145.20 EDN03591.1 - 1e-30 106.9 0.8 1.8e-30 106.1 0.5 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EDN03591.1 - 0.048 13.1 0.0 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 SPFH domain-Band 7 family DRTGG PF07085.7 EDN03591.1 - 0.13 11.8 1.6 0.65 9.6 0.1 2.4 2 0 0 2 2 2 0 DRTGG domain DUF3659 PF12396.3 EDN03591.1 - 0.21 11.2 1.3 0.29 10.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Hira PF07569.6 EDN03592.1 - 1.1e-82 276.5 0.0 2.1e-82 275.5 0.0 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EDN03592.1 - 6e-36 121.0 24.7 1.1e-06 28.3 0.0 8.9 8 0 0 8 8 8 8 WD domain, G-beta repeat HIRA_B PF09453.5 EDN03592.1 - 2.7e-10 39.5 0.2 6.9e-10 38.2 0.1 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EDN03592.1 - 0.0001 21.8 1.4 32 4.3 0.0 5.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 EDN03592.1 - 0.02 14.6 0.1 3 7.5 0.0 3.0 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 EDN03592.1 - 0.11 10.2 0.1 0.62 7.8 0.0 2.0 3 0 0 3 3 3 0 IKI3 family DDE_1 PF03184.14 EDN03593.1 - 1.7e-52 177.6 0.0 2.8e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN03593.1 - 3.4e-11 42.7 0.0 6.6e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN03593.1 - 4.2e-06 26.2 0.1 1e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain zf-CCHC_4 PF14392.1 EDN03593.1 - 0.12 12.1 0.1 0.29 10.8 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.14 EDN03594.1 - 1.8e-43 148.2 0.0 1.2e-42 145.5 0.0 2.2 2 1 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN03594.1 - 0.0023 17.6 0.0 0.035 13.8 0.0 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN03594.1 - 0.024 14.4 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain RVT_1 PF00078.22 EDN03595.1 - 1.5e-24 86.5 0.0 3.1e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN03595.1 - 3e-16 59.6 0.8 1.2e-15 57.6 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain Chromo PF00385.19 EDN03595.1 - 1.5e-13 50.2 2.5 2.1e-13 49.6 0.7 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.18 EDN03595.1 - 1.5e-05 24.6 1.0 3.4e-05 23.5 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EDN03595.1 - 0.00018 21.4 2.7 0.00018 21.4 1.9 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein Mtf2_C PF14061.1 EDN03595.1 - 0.045 13.6 0.6 0.15 11.9 0.1 2.0 1 1 1 2 2 2 0 Polycomb-like MTF2 factor 2 zf-CCHC_4 PF14392.1 EDN03595.1 - 0.25 11.0 1.4 0.57 9.8 1.0 1.6 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 EDN03598.1 - 2.5e-16 59.8 0.0 5.1e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EDN03599.1 - 4.2e-06 26.2 0.0 1.1e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EDN03599.1 - 0.0095 15.8 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease UBN2 PF14223.1 EDN03599.1 - 0.011 15.5 1.3 0.026 14.2 0.3 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type gag-asp_proteas PF13975.1 EDN03599.1 - 0.026 14.3 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDN03599.1 - 0.047 14.1 0.0 0.098 13.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.6 EDN03599.1 - 0.096 12.6 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease RNase_H PF00075.19 EDN03600.1 - 3e-15 56.7 0.0 4.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN03600.1 - 0.078 12.7 0.1 0.28 10.9 0.1 2.0 1 1 0 1 1 1 0 Reverse transcriptase-like PAP2 PF01569.16 EDN03601.1 - 4.2e-08 32.9 5.4 1.9e-07 30.7 0.6 2.8 2 1 0 2 2 2 1 PAP2 superfamily DUF2628 PF10947.3 EDN03601.1 - 8.6 6.2 7.5 41 4.0 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) Mod_r PF07200.8 EDN03602.1 - 4.5e-13 49.3 1.2 5.9e-13 48.9 0.8 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Ank_5 PF13857.1 EDN03603.1 - 3e-10 39.9 0.2 2.6e-09 37.0 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN03603.1 - 3.6e-07 30.5 0.0 8.9e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EDN03603.1 - 3.1e-05 23.5 0.5 0.00066 19.3 0.1 2.7 2 1 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EDN03603.1 - 5.7e-05 23.3 0.1 0.00015 21.9 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EDN03603.1 - 0.00016 21.5 0.2 0.00099 19.1 0.1 2.4 2 1 0 2 2 2 1 Ankyrin repeat YejG PF13989.1 EDN03603.1 - 0.00056 19.9 0.0 0.0009 19.2 0.0 1.3 1 0 0 1 1 1 1 YejG-like protein tRNA_lig_CPD PF08302.6 EDN03604.1 - 2.1e-92 308.9 0.0 3e-92 308.4 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 EDN03604.1 - 1e-81 273.6 0.0 2.3e-81 272.5 0.0 1.6 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 EDN03604.1 - 3.8e-49 166.7 0.1 7.1e-49 165.8 0.1 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_33 PF13671.1 EDN03604.1 - 0.0062 16.4 0.1 0.018 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN03604.1 - 0.013 16.2 0.0 0.092 13.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Got1 PF04178.7 EDN03605.1 - 1.6e-31 108.8 16.8 1.6e-31 108.8 11.7 2.1 2 0 0 2 2 2 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 EDN03605.1 - 0.03 13.2 0.0 0.063 12.2 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M50 Syndecan PF01034.15 EDN03605.1 - 0.053 13.1 0.5 0.19 11.3 0.3 1.9 1 0 0 1 1 1 0 Syndecan domain HLH PF00010.21 EDN03606.1 - 6.2e-13 48.2 0.0 1.5e-12 47.0 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mito_carr PF00153.22 EDN03607.1 - 1.1e-12 47.5 0.0 1.1e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Dna2 PF08696.6 EDN03608.1 - 4.5e-76 254.7 0.1 7e-75 250.9 0.0 2.3 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 EDN03608.1 - 2.1e-51 174.1 0.0 3.7e-51 173.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EDN03608.1 - 3.3e-41 141.4 0.2 2.9e-21 76.1 0.0 2.9 2 1 1 3 3 3 2 AAA domain Cas_Cas4 PF01930.12 EDN03608.1 - 3.7e-13 49.7 0.1 1.8e-10 41.0 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 AAA_30 PF13604.1 EDN03608.1 - 3.7e-13 49.5 0.0 1.1e-12 47.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain PDDEXK_1 PF12705.2 EDN03608.1 - 1.9e-12 47.1 0.6 3.8e-12 46.1 0.1 1.7 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily AAA_19 PF13245.1 EDN03608.1 - 4.7e-11 42.2 0.2 1.1e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EDN03608.1 - 1.9e-07 30.8 0.9 0.22 11.0 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF911 PF06023.7 EDN03608.1 - 2.8e-06 26.7 0.0 1.1e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Archaeal protein of unknown function (DUF911) CbiA PF01656.18 EDN03608.1 - 6.3e-05 22.4 0.0 0.00016 21.1 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Helicase_RecD PF05127.9 EDN03608.1 - 0.00012 21.7 0.0 0.00031 20.4 0.0 1.7 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.1 EDN03608.1 - 0.00021 21.3 0.0 0.0018 18.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.17 EDN03608.1 - 0.00024 20.6 0.1 0.00043 19.7 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PIF1 PF05970.9 EDN03608.1 - 0.00056 18.9 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 PIF1-like helicase MobB PF03205.9 EDN03608.1 - 0.001 18.7 0.0 0.0029 17.3 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B UvrD-helicase PF00580.16 EDN03608.1 - 0.0012 18.1 0.2 0.0033 16.7 0.1 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 EDN03608.1 - 0.0045 16.4 0.1 0.015 14.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain DUF2075 PF09848.4 EDN03608.1 - 0.0053 15.7 0.0 0.0097 14.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 EDN03608.1 - 0.0054 16.4 0.0 0.18 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EDN03608.1 - 0.0058 16.5 0.1 0.083 12.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDN03608.1 - 0.011 15.8 0.1 0.076 13.1 0.0 2.5 2 1 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EDN03608.1 - 0.011 15.1 0.1 0.031 13.7 0.1 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.14 EDN03608.1 - 0.016 14.6 0.1 0.056 12.8 0.0 1.9 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF853 PF05872.7 EDN03608.1 - 0.029 12.7 0.1 0.048 12.0 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_10 PF12846.2 EDN03608.1 - 0.06 12.7 0.0 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain ArgK PF03308.11 EDN03608.1 - 0.065 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 ArgK protein DUF87 PF01935.12 EDN03608.1 - 0.071 12.9 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA PF00004.24 EDN03608.1 - 0.092 12.9 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EDN03608.1 - 0.12 12.0 0.1 0.34 10.5 0.1 1.7 1 0 0 1 1 1 0 NTPase Ribonuc_P_40 PF08584.6 EDN03609.1 - 1.5e-12 47.1 0.0 1.7e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.27 EDN03610.1 - 3.9e-32 108.9 15.7 1.3e-08 34.3 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EDN03610.1 - 1.3e-10 40.0 0.0 3e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EDN03610.1 - 1.9e-05 24.4 0.1 0.083 12.5 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EDN03610.1 - 0.0013 16.9 0.2 0.048 11.7 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 IKI3 PF04762.7 EDN03610.1 - 0.019 12.7 0.0 0.053 11.3 0.0 1.6 2 0 0 2 2 2 0 IKI3 family Apc4_WD40 PF12894.2 EDN03610.1 - 0.11 11.9 0.0 0.34 10.4 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 EDN03610.1 - 0.18 10.6 0.0 0.69 8.6 0.0 1.8 2 0 0 2 2 2 0 Coatomer WD associated region VID27 PF08553.5 EDN03610.1 - 0.25 9.5 0.2 0.35 9.0 0.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Ribosomal_L2_C PF03947.13 EDN03612.1 - 1.3e-37 128.5 0.7 1.1e-32 112.5 0.6 2.6 2 0 0 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EDN03612.1 - 1.9e-29 101.3 0.7 3.3e-29 100.6 0.5 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Dynactin_p62 PF05502.8 EDN03613.1 - 1.4 7.6 9.8 2.2 6.9 6.8 1.3 1 0 0 1 1 1 0 Dynactin p62 family VirionAssem_T7 PF11653.3 EDN03613.1 - 1.7 9.4 10.1 0.18 12.5 2.9 2.2 1 1 2 3 3 3 0 Bacteriophage T7 virion assembly protein HABP4_PAI-RBP1 PF04774.10 EDN03613.1 - 2.7 8.5 12.9 0.19 12.2 4.8 2.0 2 1 0 2 2 2 0 Hyaluronan / mRNA binding family HIT PF01230.18 EDN03614.1 - 4.1e-15 56.0 0.3 8.2e-15 55.1 0.0 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EDN03614.1 - 0.00047 20.3 0.2 0.0011 19.1 0.1 1.6 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EDN03614.1 - 0.0015 18.1 0.2 0.006 16.2 0.1 2.0 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 UPF0020 PF01170.13 EDN03615.1 - 2.5e-10 40.2 0.0 4.4e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EDN03615.1 - 2e-08 34.2 0.0 3.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EDN03615.1 - 0.0042 16.2 0.0 0.0065 15.5 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.10 EDN03615.1 - 0.0046 16.4 0.4 0.014 14.8 0.0 1.9 3 0 0 3 3 3 1 D12 class N6 adenine-specific DNA methyltransferase N6_N4_Mtase PF01555.13 EDN03615.1 - 0.0093 15.4 0.0 0.086 12.3 0.0 2.2 2 0 0 2 2 2 1 DNA methylase YojJ PF10372.4 EDN03616.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus DUF4622 PF15415.1 EDN03616.1 - 0.11 11.2 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4622) DUF2985 PF11204.3 EDN03617.1 - 2.7e-23 81.5 3.6 6.1e-23 80.3 2.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) SIR2 PF02146.12 EDN03618.1 - 5.1e-60 202.2 0.0 7.3e-60 201.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EDN03618.1 - 8.2e-05 22.2 0.2 0.00016 21.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EDN03618.1 - 0.00061 19.5 0.1 0.36 10.6 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain zf-4CXXC_R1 PF10497.4 EDN03618.1 - 0.044 13.9 0.7 0.089 12.9 0.5 1.4 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Ribosomal_L34e PF01199.13 EDN03618.1 - 0.13 12.4 0.3 0.24 11.6 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L34e TPR_12 PF13424.1 EDN03619.1 - 3.5e-13 49.2 0.0 8.8e-07 28.7 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDN03619.1 - 3.1e-11 42.7 0.1 1.3e-05 24.7 0.0 3.5 2 1 2 4 4 4 2 TPR repeat TPR_16 PF13432.1 EDN03619.1 - 6.5e-10 39.4 4.8 1.2e-05 25.7 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDN03619.1 - 1.2e-08 35.1 4.1 0.001 19.3 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDN03619.1 - 1.6e-08 33.8 0.0 0.00064 19.4 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDN03619.1 - 1.5e-06 27.5 0.1 0.0021 17.5 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDN03619.1 - 2.4e-06 26.8 0.0 0.00024 20.6 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN03619.1 - 1.3e-05 25.4 10.7 0.2 12.4 0.0 5.4 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDN03619.1 - 2.6e-05 23.9 7.9 1.6 8.6 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 EDN03619.1 - 4e-05 22.8 1.6 0.12 11.4 0.0 3.4 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EDN03619.1 - 0.00012 21.8 4.1 1.2 9.1 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDN03619.1 - 0.0023 18.0 0.0 28 5.2 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDN03619.1 - 0.0056 16.3 0.5 0.2 11.5 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EDN03619.1 - 0.045 12.9 0.0 0.16 11.2 0.0 2.0 1 0 0 1 1 1 0 SHNi-TPR TPR_5 PF12688.2 EDN03619.1 - 0.17 11.8 1.2 33 4.5 0.0 3.1 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_21 PF09976.4 EDN03619.1 - 0.19 11.6 2.4 0.48 10.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDN03619.1 - 0.63 10.6 4.6 6.9 7.3 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat NOA36 PF06524.7 EDN03619.1 - 5.1 6.2 6.1 6.8 5.8 4.2 1.2 1 0 0 1 1 1 0 NOA36 protein RWD PF05773.17 EDN03620.1 - 5e-25 87.6 0.3 5e-25 87.6 0.2 1.6 2 0 0 2 2 2 1 RWD domain DHHA2 PF02833.9 EDN03620.1 - 0.022 14.9 1.9 0.038 14.2 1.1 1.6 1 1 0 1 1 1 0 DHHA2 domain DDHD PF02862.12 EDN03620.1 - 0.039 13.7 1.6 0.051 13.3 1.1 1.1 1 0 0 1 1 1 0 DDHD domain UQ_con PF00179.21 EDN03622.1 - 1e-19 70.3 0.0 1.2e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDN03622.1 - 0.025 14.4 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain Sec7_N PF12783.2 EDN03623.1 - 3.4e-40 137.2 2.8 3.4e-40 137.2 1.9 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EDN03623.1 - 0.0016 17.9 0.0 0.0088 15.5 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) DUF3926 PF13080.1 EDN03623.1 - 0.014 14.9 0.7 0.036 13.6 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) Vps26 PF03643.10 EDN03624.1 - 2e-101 338.4 0.2 2.6e-101 338.0 0.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 AAA_18 PF13238.1 EDN03625.1 - 4.1e-12 46.5 0.0 1e-11 45.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDN03625.1 - 4.9e-12 45.9 0.0 1.3e-11 44.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN03625.1 - 3.8e-10 40.6 0.3 4.2e-09 37.2 0.2 2.1 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 EDN03625.1 - 6.9e-10 39.0 0.2 0.00052 19.9 0.0 2.3 2 0 0 2 2 2 2 Shikimate kinase Rad17 PF03215.10 EDN03625.1 - 3.1e-07 29.4 0.0 4.9e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 EDN03625.1 - 1.8e-05 24.4 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EDN03625.1 - 2.5e-05 24.4 0.0 4.2e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDN03625.1 - 8.6e-05 22.4 0.0 0.00034 20.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EDN03625.1 - 9.2e-05 22.6 0.0 0.0002 21.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EDN03625.1 - 0.00016 20.8 0.0 0.00025 20.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 EDN03625.1 - 0.0015 18.6 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EDN03625.1 - 0.0019 18.1 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EDN03625.1 - 0.0021 18.3 0.0 0.0042 17.3 0.0 1.6 1 1 0 1 1 1 1 ABC transporter Cytidylate_kin2 PF13189.1 EDN03625.1 - 0.0028 17.5 0.1 0.019 14.8 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase-like family ATP_bind_2 PF03668.10 EDN03625.1 - 0.0032 16.5 0.1 0.13 11.2 0.0 2.1 2 0 0 2 2 2 1 P-loop ATPase protein family AAA_28 PF13521.1 EDN03625.1 - 0.0034 17.3 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDN03625.1 - 0.0042 16.1 0.0 0.0069 15.4 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 EDN03625.1 - 0.0063 16.2 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 NTPase AAA_5 PF07728.9 EDN03625.1 - 0.0072 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EDN03625.1 - 0.0075 15.1 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_24 PF13479.1 EDN03625.1 - 0.0082 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN03625.1 - 0.0089 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain PRK PF00485.13 EDN03625.1 - 0.01 15.4 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.15 EDN03625.1 - 0.011 15.3 0.1 0.052 13.2 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase PhoH PF02562.11 EDN03625.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 EDN03625.1 - 0.014 14.8 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EDN03625.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EDN03625.1 - 0.018 13.9 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ADK PF00406.17 EDN03625.1 - 0.019 14.8 0.1 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase Arch_ATPase PF01637.13 EDN03625.1 - 0.023 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase CoaE PF01121.15 EDN03625.1 - 0.024 14.0 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase Viral_helicase1 PF01443.13 EDN03625.1 - 0.04 13.4 0.0 0.074 12.5 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DNA_pol3_delta2 PF13177.1 EDN03625.1 - 0.046 13.3 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 EDN03625.1 - 0.046 12.8 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 EDN03625.1 - 0.052 12.7 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 EDN03625.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain KTI12 PF08433.5 EDN03625.1 - 0.085 12.0 0.1 0.29 10.3 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 IstB_IS21 PF01695.12 EDN03625.1 - 0.099 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein 2-oxoacid_dh PF00198.18 EDN03626.1 - 1e-78 263.7 0.1 1.4e-78 263.3 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EDN03626.1 - 3.3e-13 49.0 0.0 7.1e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EDN03626.1 - 8.4e-13 47.7 0.3 2e-12 46.5 0.2 1.7 1 0 0 1 1 1 1 e3 binding domain Cid2 PF09774.4 EDN03627.1 - 2e-52 177.2 0.0 2.4e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Fapy_DNA_glyco PF01149.19 EDN03628.1 - 3.7e-27 94.9 1.0 1.1e-26 93.5 0.0 2.0 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EDN03628.1 - 2.4e-21 75.2 0.0 4.3e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EDN03628.1 - 0.0095 14.5 0.0 0.018 13.6 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF2263 PF10021.4 EDN03629.1 - 1.8e-32 112.3 0.0 3.2e-32 111.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Fe_hyd_lg_C PF02906.9 EDN03630.1 - 9.5e-61 205.5 0.0 2.2e-60 204.3 0.0 1.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain HTH_18 PF12833.2 EDN03630.1 - 0.085 12.9 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain DNA_RNApol_7kD PF03604.8 EDN03631.1 - 8.4e-17 60.3 6.9 1.1e-16 59.9 4.8 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.14 EDN03631.1 - 0.0014 18.3 0.2 0.0014 18.3 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DUF2197 PF09963.4 EDN03631.1 - 0.0014 18.5 2.0 0.13 12.2 0.1 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) A2L_zn_ribbon PF08792.5 EDN03631.1 - 0.0018 17.6 2.2 0.18 11.2 0.1 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain DUF2318 PF10080.4 EDN03631.1 - 0.0031 17.2 0.2 0.0032 17.1 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) DZR PF12773.2 EDN03631.1 - 0.0045 16.7 0.5 0.0062 16.3 0.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon Zn-ribbon_8 PF09723.5 EDN03631.1 - 0.0066 16.3 1.9 0.012 15.5 1.3 1.4 1 0 0 1 1 1 1 Zinc ribbon domain Rubredoxin PF00301.15 EDN03631.1 - 0.012 15.4 0.1 0.47 10.3 0.0 2.1 2 0 0 2 2 2 0 Rubredoxin GFA PF04828.9 EDN03631.1 - 0.021 14.7 1.1 2.6 8.0 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2296 PF10058.4 EDN03631.1 - 0.087 12.5 0.2 0.91 9.3 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Rep_fac-A_C PF08646.5 EDN03631.1 - 0.092 12.4 0.4 0.099 12.3 0.3 1.1 1 0 0 1 1 1 0 Replication factor-A C terminal domain DUF3268 PF11672.3 EDN03631.1 - 0.11 12.5 1.2 0.53 10.3 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3268) DUF2082 PF09855.4 EDN03631.1 - 0.15 11.9 1.0 0.18 11.6 0.1 1.6 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) TFIIS_C PF01096.13 EDN03631.1 - 0.2 11.3 4.4 5 6.8 0.5 2.5 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 EDN03631.1 - 0.21 11.4 3.7 1 9.2 2.7 1.9 1 1 1 2 2 2 0 Transposase zinc-ribbon domain RRN7 PF11781.3 EDN03631.1 - 0.28 10.7 0.2 0.28 10.7 0.1 2.1 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF951 PF06107.6 EDN03631.1 - 0.29 10.6 3.2 1.2 8.7 0.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) Ribosomal_L40e PF01020.12 EDN03631.1 - 0.37 10.4 3.5 0.53 9.9 2.5 1.2 1 0 0 1 1 1 0 Ribosomal L40e family OrfB_Zn_ribbon PF07282.6 EDN03631.1 - 0.63 9.7 3.8 1.3 8.7 2.4 1.6 1 1 1 2 2 2 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.7 EDN03631.1 - 0.72 9.2 5.4 7.6 5.9 0.3 2.2 1 1 2 3 3 3 0 TFIIB zinc-binding Zn_ribbon_recom PF13408.1 EDN03631.1 - 0.88 9.8 7.1 2.4 8.4 0.7 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf-DNL PF05180.7 EDN03631.1 - 4.6 7.0 6.0 7.5 6.3 0.1 2.5 2 1 1 3 3 2 0 DNL zinc finger Glycos_transf_3 PF00591.16 EDN03632.1 - 1.5e-60 204.7 0.0 2.2e-49 168.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EDN03632.1 - 8.3e-07 28.5 0.2 1.5e-06 27.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain PI-PLC-X PF00388.14 EDN03633.1 - 1.2e-07 31.1 0.0 2.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain NARP1 PF12569.3 EDN03634.1 - 4.7e-214 711.9 16.4 4.6e-212 705.3 9.6 2.4 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 EDN03634.1 - 7e-22 75.5 31.3 2.2e-05 24.0 0.2 11.4 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 EDN03634.1 - 5.7e-20 70.0 20.9 0.015 15.8 0.2 10.5 8 2 2 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 EDN03634.1 - 9.5e-20 70.0 38.8 6.8e-06 25.6 1.2 7.6 6 2 2 9 9 8 6 TPR repeat TPR_16 PF13432.1 EDN03634.1 - 2.5e-18 66.1 26.5 0.00096 19.7 0.0 8.7 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EDN03634.1 - 3e-18 65.9 28.6 0.0019 18.4 0.6 7.4 6 2 1 7 7 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 EDN03634.1 - 1e-12 47.0 24.6 3.7e-05 23.1 0.3 9.0 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EDN03634.1 - 1.7e-10 39.8 17.0 0.00025 20.5 0.2 7.5 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDN03634.1 - 2.5e-09 36.6 17.2 0.86 9.9 0.0 9.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDN03634.1 - 2.6e-09 36.8 29.5 0.00075 19.3 0.5 8.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 EDN03634.1 - 5.6e-08 32.5 11.8 0.00024 20.8 0.3 6.3 5 2 1 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EDN03634.1 - 1.5e-06 28.2 20.0 0.1 12.7 0.1 6.1 5 3 1 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EDN03634.1 - 4.4e-05 22.9 19.4 0.042 13.6 0.1 7.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 EDN03634.1 - 0.00051 20.2 12.3 0.3 11.6 0.5 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat BTAD PF03704.12 EDN03634.1 - 0.00088 19.5 0.8 0.00088 19.5 0.6 3.2 3 0 0 3 3 2 1 Bacterial transcriptional activator domain TPR_5 PF12688.2 EDN03634.1 - 0.016 15.2 0.2 0.32 11.0 0.0 3.1 2 1 0 2 2 2 0 Tetratrico peptide repeat TPR_6 PF13174.1 EDN03634.1 - 0.075 13.5 24.0 2.5 8.7 0.2 7.9 10 0 0 10 10 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDN03634.1 - 3.8 7.5 22.3 13 5.8 1.2 7.8 10 0 0 10 10 9 0 Tetratricopeptide repeat Tim54 PF11711.3 EDN03635.1 - 8.7e-75 251.6 11.9 1.6e-58 198.1 4.2 3.0 2 1 0 2 2 2 2 Inner membrane protein import complex subunit Tim54 Glu_synthase PF01645.12 EDN03635.1 - 7.1e-12 44.9 0.0 1.2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Pkinase PF00069.20 EDN03636.1 - 2.1e-49 168.0 0.2 3.7e-33 114.7 0.2 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN03636.1 - 2.7e-21 75.8 0.6 7.4e-16 57.9 0.1 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EDN03636.1 - 0.00034 20.4 0.2 0.025 14.2 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EDN03636.1 - 0.00079 18.4 0.0 0.002 17.1 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EDN03636.1 - 0.017 13.9 0.1 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EDN03636.1 - 0.044 12.5 0.1 0.068 11.9 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EDN03636.1 - 0.086 11.8 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-met PF12874.2 EDN03637.1 - 1.9e-05 24.6 0.6 4.2e-05 23.5 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DNA_ligase_OB_2 PF14743.1 EDN03637.1 - 0.0046 16.5 0.2 0.24 11.0 0.0 3.3 4 0 0 4 4 4 1 DNA ligase OB-like domain PRP4 PF08799.6 EDN03637.1 - 0.057 12.7 0.9 0.1 11.8 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like GATase_5 PF13507.1 EDN03637.1 - 0.14 10.9 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain zf-U1 PF06220.7 EDN03637.1 - 0.65 9.6 2.5 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 U1 zinc finger CAP_GLY PF01302.20 EDN03638.1 - 2.9e-19 68.5 0.2 4.7e-19 67.8 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EDN03638.1 - 6.7e-14 51.1 2.6 0.0011 18.4 0.2 5.0 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EDN03638.1 - 2.6e-07 29.7 5.1 0.8 9.9 0.1 5.7 5 1 1 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 EDN03638.1 - 3.2e-07 29.4 0.6 0.096 12.9 0.0 5.8 6 0 0 6 6 6 1 Leucine rich repeat LRR_8 PF13855.1 EDN03638.1 - 5e-06 26.1 5.5 0.018 14.7 1.7 4.2 3 1 1 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EDN03638.1 - 7.1e-05 22.4 6.3 0.49 10.6 0.1 6.0 6 1 0 7 7 7 1 Leucine Rich repeat GIDE PF12483.3 EDN03638.1 - 0.13 11.5 0.2 0.26 10.6 0.2 1.4 1 0 0 1 1 1 0 E3 Ubiquitin ligase DDE_1 PF03184.14 EDN03639.1 - 3.9e-36 124.2 0.0 2.1e-17 62.9 0.0 2.4 2 1 1 3 3 3 2 DDE superfamily endonuclease zf-CCHC_4 PF14392.1 EDN03639.1 - 0.0067 16.0 0.3 0.012 15.2 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle DDE_3 PF13358.1 EDN03639.1 - 0.013 15.2 0.0 0.47 10.2 0.0 2.4 1 1 0 1 1 1 0 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN03639.1 - 0.024 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain zf-CCHC PF00098.18 EDN03639.1 - 0.041 13.8 0.5 0.093 12.7 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EDN03639.1 - 0.13 11.9 1.3 0.28 10.9 0.9 1.5 1 0 0 1 1 1 0 Zinc knuckle DDE_1 PF03184.14 EDN03640.1 - 1.3e-07 30.9 0.0 4.9e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN03640.1 - 0.0026 17.5 0.0 0.013 15.3 0.0 2.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Borrelia_P83 PF05262.6 EDN03640.1 - 1.1 7.4 21.3 1.5 6.9 14.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PLRV_ORF5 PF01690.12 EDN03640.1 - 5.8 5.9 11.4 10 5.1 7.9 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein AAA PF00004.24 EDN03641.1 - 3.2e-17 62.9 0.0 7.3e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN03641.1 - 4.7e-05 23.4 0.1 0.0036 17.3 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 EDN03641.1 - 0.00034 20.9 0.8 0.17 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN03641.1 - 0.00074 20.3 1.6 0.0018 19.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDN03641.1 - 0.00095 18.9 0.0 0.0027 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN03641.1 - 0.0014 18.7 0.4 0.057 13.5 0.0 3.1 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EDN03641.1 - 0.0096 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EDN03641.1 - 0.021 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EDN03641.1 - 0.03 13.8 0.0 0.075 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDN03641.1 - 0.075 13.2 0.0 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_3 PF07726.6 EDN03641.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2205 PF10224.4 EDN03643.1 - 2.3e-16 59.1 0.2 3.8e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Ku_PK_bind PF08785.6 EDN03643.1 - 0.1 12.5 0.3 0.18 11.6 0.0 1.5 2 0 0 2 2 2 0 Ku C terminal domain like Rapamycin_bind PF08771.6 EDN03643.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Rapamycin binding domain Hpt PF01627.18 EDN03643.1 - 0.22 11.5 1.1 0.4 10.6 0.8 1.4 1 0 0 1 1 1 0 Hpt domain V-SNARE PF05008.10 EDN03643.1 - 0.3 11.2 2.5 0.52 10.5 0.5 2.0 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF288 PF03385.12 EDN03644.1 - 0.13 10.7 0.0 0.2 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF288 DDE_1 PF03184.14 EDN03645.1 - 1.9e-39 135.0 0.0 5.2e-39 133.6 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN03645.1 - 9e-06 25.5 0.0 3.1e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN03647.1 - 3.9e-05 23.4 0.3 9.1e-05 22.2 0.2 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 EDN03648.1 - 0.037 14.1 0.0 0.07 13.2 0.0 1.5 1 1 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.1 EDN03648.1 - 0.061 12.9 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.1 EDN03648.1 - 0.066 13.2 0.2 0.46 10.5 0.1 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain DUF3435 PF11917.3 EDN03649.1 - 4e-150 500.1 1.2 5.2e-150 499.7 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF896 PF05979.7 EDN03649.1 - 0.25 10.9 3.6 7.5 6.2 0.1 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) zf-C2H2_4 PF13894.1 EDN03649.1 - 1.1 9.7 5.7 0.82 10.1 1.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.7 EDN03650.1 - 3.5e-08 32.8 0.7 5.5e-08 32.2 0.5 1.3 1 0 0 1 1 1 1 U1 zinc finger ABC_tran_2 PF12848.2 EDN03650.1 - 0.12 12.2 2.0 0.32 10.8 0.7 2.1 2 0 0 2 2 2 0 ABC transporter Zn_clus PF00172.13 EDN03651.1 - 1.2e-08 34.6 10.5 2.1e-08 33.8 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 EDN03652.1 - 4.2e-54 182.3 0.0 5.6e-54 181.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDN03652.1 - 4.7e-14 51.9 0.0 5.9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EDN03652.1 - 0.00077 19.3 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EDN03652.1 - 0.035 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain CwfJ_C_1 PF04677.10 EDN03653.1 - 1.3e-31 108.8 0.0 3.7e-31 107.3 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EDN03653.1 - 4e-25 88.1 0.0 4e-25 88.1 0.0 2.2 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 ATP_bind_1 PF03029.12 EDN03654.1 - 8.2e-69 231.7 0.0 1.1e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 EDN03654.1 - 2.3e-05 23.3 0.2 0.002 16.9 0.0 2.2 2 0 0 2 2 2 1 ArgK protein GTP_EFTU PF00009.22 EDN03654.1 - 8e-05 22.1 0.0 0.006 16.0 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EDN03654.1 - 0.00044 20.7 0.0 0.35 11.3 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EDN03654.1 - 0.00045 20.1 0.0 0.0025 17.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDN03654.1 - 0.00066 18.9 0.0 0.034 13.4 0.0 2.9 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_22 PF13401.1 EDN03654.1 - 0.0008 19.5 0.0 0.0039 17.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain Arf PF00025.16 EDN03654.1 - 0.0016 17.6 0.0 3.1 6.9 0.0 3.1 2 1 0 2 2 2 2 ADP-ribosylation factor family NACHT PF05729.7 EDN03654.1 - 0.0031 17.2 0.0 0.021 14.5 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 EDN03654.1 - 0.0047 16.8 0.0 0.0099 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain PRK PF00485.13 EDN03654.1 - 0.0059 16.1 0.0 0.085 12.4 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 EDN03654.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.9 EDN03654.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EDN03654.1 - 0.014 14.8 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EDN03654.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EDN03654.1 - 0.02 13.7 0.1 0.042 12.6 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 EDN03654.1 - 0.031 15.0 2.8 0.044 14.5 0.0 2.3 2 1 0 2 2 1 0 AAA domain cobW PF02492.14 EDN03654.1 - 0.033 13.6 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.12 EDN03654.1 - 0.035 13.4 0.0 3.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase PduV-EutP PF10662.4 EDN03654.1 - 0.043 13.3 0.1 1.7 8.1 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CbiA PF01656.18 EDN03654.1 - 0.091 12.1 0.3 0.41 10.0 0.0 2.1 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 EDN03654.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 EDN03654.1 - 0.93 8.1 4.9 2.3 6.7 0.0 2.7 3 1 0 3 3 3 0 G-protein alpha subunit SUZ PF12752.2 EDN03657.1 - 0.0057 17.1 7.0 0.0057 17.1 4.9 2.6 1 1 1 2 2 2 1 SUZ domain Synaphin PF05835.7 EDN03657.1 - 0.098 12.8 4.3 0.21 11.7 3.0 1.5 1 0 0 1 1 1 0 Synaphin protein NUP50 PF08911.6 EDN03657.1 - 1.1 9.6 11.1 3.3 8.1 2.6 3.0 2 1 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) Senescence_reg PF04520.8 EDN03657.1 - 4.1 7.8 9.7 7.2 7.0 4.3 2.6 1 1 1 2 2 2 0 Senescence regulator TPPII_N PF12583.3 EDN03658.1 - 0.25 11.4 2.2 0.31 11.1 1.4 1.3 1 1 0 1 1 1 0 Tripeptidyl peptidase II N terminal DUF1661 PF07877.6 EDN03659.1 - 1.2 8.6 5.8 7.7 6.1 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) Aldo_ket_red PF00248.16 EDN03660.1 - 1.9e-11 43.3 0.4 3.6e-10 39.1 0.0 2.4 1 1 1 2 2 2 2 Aldo/keto reductase family MoCF_biosynth PF00994.19 EDN03661.1 - 0.15 11.4 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Probable molybdopterin binding domain F-box-like PF12937.2 EDN03662.1 - 0.0001 21.9 0.2 0.00044 19.9 0.1 2.2 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EDN03662.1 - 0.0045 16.9 0.4 8.7 6.7 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.28 EDN03662.1 - 3.6 7.9 8.1 77 3.9 0.0 5.8 7 0 0 7 7 7 0 Leucine Rich Repeat BSD PF03909.12 EDN03663.1 - 4.8e-26 90.2 14.1 4.3e-15 55.1 0.3 3.7 4 0 0 4 4 4 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EDN03663.1 - 1.8e-12 46.7 0.0 5.5e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Syntaxin PF00804.20 EDN03663.1 - 0.097 12.8 3.4 1.3 9.2 0.1 2.9 2 0 0 2 2 2 0 Syntaxin DDE_1 PF03184.14 EDN03664.1 - 2e-08 33.6 0.1 6.7e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN03664.1 - 1.4e-07 31.2 0.0 2.9e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Nucleo_P87 PF07267.6 EDN03665.1 - 0.019 13.6 3.9 0.025 13.3 2.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.1 EDN03665.1 - 4.9 7.5 7.4 1.2 9.4 2.9 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HTH_29 PF13551.1 EDN03666.1 - 3.5e-06 27.1 0.0 1.4e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EDN03666.1 - 6e-06 25.7 0.2 0.0007 19.1 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EDN03666.1 - 6.2e-06 25.9 0.0 5.1e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_33 PF13592.1 EDN03666.1 - 2.7e-05 23.6 0.0 8e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 EDN03666.1 - 3.4e-05 23.2 0.0 0.00045 19.7 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.1 EDN03666.1 - 0.0011 18.9 0.0 0.1 12.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.13 EDN03666.1 - 0.0084 15.8 0.0 0.014 15.1 0.0 1.4 1 1 0 1 1 1 1 'Paired box' domain HTH_Tnp_IS630 PF01710.11 EDN03666.1 - 0.021 14.4 0.0 0.031 13.9 0.0 1.5 1 1 0 1 1 1 0 Transposase Terminase_5 PF06056.7 EDN03666.1 - 0.051 13.1 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) DUF1751 PF08551.5 EDN03668.1 - 0.017 15.4 0.3 0.035 14.4 0.0 1.7 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) PHD PF00628.24 EDN03669.1 - 9.3e-10 38.0 8.2 1.5e-09 37.4 5.7 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EDN03669.1 - 0.00041 20.5 0.0 0.00073 19.7 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 EDN03669.1 - 0.023 14.8 2.0 0.044 13.9 1.4 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Transket_pyr PF02779.19 EDN03670.1 - 5.9e-65 218.0 0.0 9.6e-65 217.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EDN03670.1 - 1e-49 168.8 0.0 1.5e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component PNTB PF02233.11 EDN03671.1 - 2.3e-42 145.3 0.3 2.6e-42 145.1 0.2 1.0 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit Sld5 PF05916.6 EDN03675.1 - 2.5e-09 37.4 0.0 3.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Microtub_assoc PF07989.6 EDN03677.1 - 0.042 13.6 12.2 0.042 13.6 5.7 2.5 1 1 1 2 2 2 0 Microtubule associated APG6 PF04111.7 EDN03677.1 - 1.5 7.7 12.4 2.5 7.0 8.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc7 PF08317.6 EDN03677.1 - 4.1 5.9 13.2 6.9 5.2 9.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF972 PF06156.8 EDN03677.1 - 7.4 6.9 11.9 3.6 7.9 5.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Sod_Fe_C PF02777.13 EDN03678.1 - 3.1e-39 133.0 0.3 5.7e-39 132.2 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EDN03678.1 - 2.3e-29 101.4 2.2 3.6e-29 100.8 1.5 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain SpoIID PF08486.5 EDN03678.1 - 0.089 13.0 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 Stage II sporulation protein Imm15 PF15590.1 EDN03678.1 - 1.4 8.0 5.7 16 4.6 1.1 3.5 3 1 1 4 4 4 0 Immunity protein 15 GCFC PF07842.7 EDN03679.1 - 4.8e-91 304.9 5.1 4.8e-91 304.9 3.5 1.4 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EDN03679.1 - 6e-14 51.5 2.9 1.2e-13 50.5 2.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EDN03679.1 - 4.1e-07 29.7 0.7 1.5e-06 27.9 0.5 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site NatB_MDM20 PF09797.4 EDN03679.1 - 0.021 13.5 0.2 0.03 13.0 0.2 1.1 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit LGFP PF08310.6 EDN03680.1 - 0.04 13.5 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 LGFP repeat DUF1162 PF06650.7 EDN03681.1 - 3.6e-77 259.2 0.0 1.7e-76 257.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1162) ATG_C PF09333.6 EDN03681.1 - 2.2e-06 27.7 0.0 4.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 EDN03682.1 - 7.7e-41 138.3 0.0 2.5e-40 136.6 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF3429 PF11911.3 EDN03683.1 - 2.9e-42 143.9 9.7 5e-42 143.2 6.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FGGY_N PF00370.16 EDN03684.1 - 5.8e-63 212.4 0.0 7.4e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EDN03684.1 - 3.8e-52 176.7 0.9 6e-48 163.1 0.2 2.3 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 EDN03684.1 - 0.06 12.6 0.2 2.3 7.4 0.0 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M41 PF01434.13 EDN03685.1 - 4.5e-68 228.8 0.2 8.5e-68 228.0 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EDN03685.1 - 1.6e-41 141.6 0.0 4.2e-41 140.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN03685.1 - 0.00013 22.1 1.2 0.041 14.0 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN03685.1 - 0.00032 21.4 0.0 0.00092 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN03685.1 - 0.0011 18.9 0.0 0.0032 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EDN03685.1 - 0.0047 16.6 0.0 0.015 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EDN03685.1 - 0.022 13.5 0.2 0.059 12.0 0.0 1.8 2 0 0 2 2 2 0 TIP49 C-terminus AAA_19 PF13245.1 EDN03685.1 - 0.026 14.2 0.1 0.081 12.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EDN03685.1 - 0.037 13.4 0.6 7.5 5.9 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_2 PF07724.9 EDN03685.1 - 0.047 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EDN03685.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.11 EDN03685.1 - 0.08 12.1 0.1 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.1 EDN03685.1 - 0.093 12.6 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Imm41 PF15583.1 EDN03685.1 - 0.12 12.2 0.2 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 41 KaiC PF06745.8 EDN03685.1 - 0.41 9.7 2.5 40 3.2 0.1 3.4 4 0 0 4 4 4 0 KaiC NTP_transferase PF00483.18 EDN03687.1 - 1.5e-47 162.0 0.0 3.6e-47 160.7 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EDN03687.1 - 9.3e-12 43.9 13.3 1.9e-09 36.5 1.8 3.8 2 1 2 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EDN03687.1 - 1.8e-09 37.8 0.0 2.8e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EDN03687.1 - 8.8e-07 28.3 1.8 8.8e-07 28.3 1.2 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 EDN03687.1 - 0.074 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase adh_short PF00106.20 EDN03688.1 - 0.00049 20.0 0.2 0.1 12.4 0.1 2.6 1 1 1 2 2 2 2 short chain dehydrogenase Nitrate_red_gam PF02665.9 EDN03689.1 - 0.047 13.0 0.2 0.091 12.0 0.1 1.4 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Suc_Fer-like PF06999.7 EDN03691.1 - 2.1e-34 119.5 0.0 1.5e-33 116.7 0.0 2.0 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Opiods_neuropep PF01160.13 EDN03691.1 - 1.6 8.5 4.0 0.71 9.6 1.0 1.7 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide 2-Hacid_dh_C PF02826.14 EDN03692.1 - 2.4e-43 147.3 0.0 4.1e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDN03692.1 - 3.9e-10 39.3 0.0 5.3e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF4129 PF13559.1 EDN03693.1 - 0.027 14.4 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) KAR9 PF08580.5 EDN03693.1 - 0.19 9.9 6.6 0.26 9.5 4.6 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Aminotran_1_2 PF00155.16 EDN03694.1 - 8.6e-38 130.2 0.0 1.1e-37 129.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CDC24 PF06395.6 EDN03696.1 - 3.9e-34 116.5 0.0 7.6e-34 115.6 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 EDN03696.1 - 7.5e-33 113.9 0.9 1.6e-32 112.7 0.6 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 EDN03696.1 - 9.4e-22 77.3 0.3 1e-20 74.0 0.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 EDN03696.1 - 1.8e-09 37.1 0.1 4.7e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.27 EDN03697.1 - 1.1e-40 136.0 6.5 2.9e-07 30.1 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EDN03697.1 - 6.1e-06 24.6 1.7 0.13 10.3 0.1 3.1 2 1 0 3 3 3 3 Nucleoporin Nup120/160 Uds1 PF15456.1 EDN03700.1 - 9.1e-46 154.8 3.7 9.1e-46 154.8 2.6 6.6 3 1 3 7 7 7 1 Up-regulated During Septation DUF3138 PF11336.3 EDN03700.1 - 0.69 8.0 3.5 1.8 6.6 1.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3138) Prp19 PF08606.6 EDN03700.1 - 2.8 7.7 16.9 0.031 13.9 1.2 4.0 4 0 0 4 4 4 0 Prp19/Pso4-like MFS_1 PF07690.11 EDN03702.1 - 1.6e-17 63.2 30.5 7.4e-16 57.7 21.2 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily UCR_hinge PF02320.11 EDN03703.1 - 3.1e-26 91.0 5.8 5.6e-26 90.2 4.0 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 EDN03703.1 - 0.014 15.0 4.9 0.014 15.0 3.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CobT PF06213.7 EDN03703.1 - 0.029 13.5 8.5 0.035 13.2 5.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4211 PF13926.1 EDN03703.1 - 0.04 13.3 1.1 0.055 12.8 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) DUF2722 PF10846.3 EDN03703.1 - 0.094 11.7 1.4 0.1 11.6 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Adeno_terminal PF02459.10 EDN03703.1 - 0.2 9.7 4.1 0.23 9.5 2.9 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein BSP_II PF05432.6 EDN03703.1 - 0.3 10.3 10.6 0.31 10.2 7.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Roughex PF06020.6 EDN03703.1 - 0.38 9.3 5.5 0.47 9.0 3.8 1.1 1 0 0 1 1 1 0 Drosophila roughex protein YqfQ PF14181.1 EDN03703.1 - 0.52 10.3 2.7 0.57 10.2 1.9 1.2 1 0 0 1 1 1 0 YqfQ-like protein ATHILA PF03078.10 EDN03703.1 - 1.1 7.8 5.8 1.2 7.6 4.0 1.2 1 0 0 1 1 1 0 ATHILA ORF-1 family TRAP_alpha PF03896.11 EDN03703.1 - 1.1 8.1 5.7 1.2 8.0 3.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pox_RNA_Pol_19 PF05320.7 EDN03703.1 - 4.7 6.9 7.2 6.1 6.5 5.0 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2890 PF11081.3 EDN03703.1 - 5 7.1 10.3 5.8 6.9 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) HSP90 PF00183.13 EDN03703.1 - 5.9 5.1 8.5 5.9 5.1 5.9 1.0 1 0 0 1 1 1 0 Hsp90 protein Coq4 PF05019.8 EDN03704.1 - 5.8e-99 329.4 0.0 7.3e-99 329.1 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 WWbp PF10349.4 EDN03705.1 - 9.6e-25 87.7 1.6 1.7e-24 86.9 1.1 1.4 1 0 0 1 1 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 EDN03705.1 - 0.00059 19.5 0.0 0.011 15.5 0.0 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EDN03705.1 - 0.0087 15.5 0.1 0.015 14.8 0.0 1.5 1 1 0 1 1 1 1 GRAM domain TMEM171 PF15471.1 EDN03705.1 - 0.68 8.6 2.8 0.92 8.2 1.9 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 FAM180 PF15173.1 EDN03707.1 - 0.0043 16.8 0.1 0.0069 16.1 0.1 1.3 1 0 0 1 1 1 1 FAM180 family COG2 PF06148.6 EDN03707.1 - 0.043 13.6 1.1 0.067 13.0 0.8 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_GPO PF05929.6 EDN03707.1 - 0.17 11.0 2.5 0.15 11.2 0.9 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4085 PF13315.1 EDN03707.1 - 0.17 11.1 9.0 0.23 10.8 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) DUF342 PF03961.8 EDN03707.1 - 0.6 8.4 3.2 0.82 8.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4248 PF14053.1 EDN03707.1 - 0.84 9.2 3.1 2.3 7.8 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) DUF4407 PF14362.1 EDN03707.1 - 6.9 5.5 7.7 15 4.4 5.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Acyltransferase PF01553.16 EDN03708.1 - 4.8e-10 38.9 0.6 0.00017 21.0 0.0 2.9 3 0 0 3 3 3 2 Acyltransferase DPM3 PF08285.6 EDN03708.1 - 0.035 13.9 5.1 0.11 12.3 3.5 1.8 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Prenyltransf PF01255.14 EDN03709.1 - 1.2e-78 263.3 0.0 1.7e-78 262.7 0.0 1.2 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Saccharop_dh PF03435.13 EDN03710.1 - 6.2e-121 404.0 0.0 7.1e-121 403.8 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EDN03710.1 - 0.00014 21.9 0.2 0.00024 21.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF2325 PF10087.4 EDN03710.1 - 0.0024 17.6 0.1 0.0047 16.7 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2325) Shikimate_DH PF01488.15 EDN03710.1 - 0.0092 16.0 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Cupin_2 PF07883.6 EDN03711.1 - 4.2e-08 32.5 0.0 7.9e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain CDO_I PF05995.7 EDN03711.1 - 0.013 14.7 0.0 0.022 13.9 0.0 1.4 1 1 0 1 1 1 0 Cysteine dioxygenase type I DUF4437 PF14499.1 EDN03711.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) GMC_oxred_N PF00732.14 EDN03712.1 - 7e-50 169.8 0.0 3.5e-30 105.1 0.0 2.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN03712.1 - 3.1e-35 121.5 0.0 5.1e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EDN03712.1 - 2.1e-05 23.5 0.2 0.042 12.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EDN03712.1 - 0.0005 20.1 0.1 0.21 11.5 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDN03712.1 - 0.00056 18.9 0.2 0.0036 16.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN03712.1 - 0.0016 18.4 0.0 0.0044 17.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EDN03712.1 - 0.0024 17.8 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.14 EDN03712.1 - 0.13 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EDN03712.1 - 0.19 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ADH_zinc_N_2 PF13602.1 EDN03713.1 - 9.3e-21 75.0 0.0 1.5e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EDN03713.1 - 1.5e-16 60.1 0.0 2.5e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EDN03713.1 - 4.1e-05 23.6 0.0 6.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding ADH_N PF08240.7 EDN03713.1 - 0.00047 19.8 0.0 0.00086 19.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fungal_trans PF04082.13 EDN03714.1 - 3.8e-11 42.3 0.1 6.1e-11 41.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN03714.1 - 1.9e-09 37.2 7.9 3.6e-09 36.3 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_15 PF00723.16 EDN03716.1 - 1.4e-61 208.4 0.0 1.4e-38 132.6 0.0 3.0 2 1 1 3 3 3 3 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EDN03716.1 - 4.3e-21 74.3 0.0 9.4e-21 73.2 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.19 EDN03717.1 - 2.6e-55 188.0 0.0 4.7e-55 187.2 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EDN03717.1 - 1.1e-28 99.0 0.0 2.3e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.1 EDN03717.1 - 0.031 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Aha1_N PF09229.6 EDN03718.1 - 5.4e-40 136.3 1.4 8.5e-40 135.7 0.9 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EDN03718.1 - 1.4e-15 57.4 0.3 2.7e-15 56.5 0.2 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein NMO PF03060.10 EDN03719.1 - 0.026 13.6 0.1 0.051 12.7 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase V_ATPase_I PF01496.14 EDN03720.1 - 1.4e-270 899.4 7.4 8.3e-146 486.8 0.0 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family CheZ PF04344.8 EDN03720.1 - 0.069 12.7 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ DUF1009 PF06230.6 EDN03720.1 - 0.095 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1009) DUF1515 PF07439.6 EDN03720.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Filament PF00038.16 EDN03720.1 - 0.15 11.5 1.6 7.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Intermediate filament protein DASH_Dam1 PF08653.5 EDN03720.1 - 0.21 11.3 1.7 41 4.0 0.0 3.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 IncA PF04156.9 EDN03720.1 - 0.3 10.6 2.0 0.32 10.5 0.2 1.9 2 0 0 2 2 2 0 IncA protein DUF3437 PF11919.3 EDN03721.1 - 2e-31 107.5 0.0 5.5e-31 106.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EDN03721.1 - 2.8e-05 23.8 0.1 0.47 10.6 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat CLASP_N PF12348.3 EDN03721.1 - 0.0037 16.6 0.0 0.015 14.6 0.0 2.1 1 0 0 1 1 1 1 CLASP N terminal HEAT_2 PF13646.1 EDN03721.1 - 0.018 15.2 0.0 7.3 6.9 0.0 4.3 5 1 0 5 5 5 0 HEAT repeats SRP-alpha_N PF04086.8 EDN03722.1 - 3.3 7.0 8.0 1.2 8.4 3.6 1.6 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Fil_haemagg_2 PF13332.1 EDN03722.1 - 10 5.9 10.0 1.5 8.5 3.7 1.8 2 0 0 2 2 2 0 Haemagluttinin repeat YTH PF04146.10 EDN03723.1 - 1.6e-35 121.7 0.0 2.7e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain Pro_CA PF00484.14 EDN03724.1 - 2.5e-44 150.9 0.1 3.1e-44 150.6 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Velvet PF11754.3 EDN03725.1 - 2.3e-56 190.6 0.0 5.3e-56 189.4 0.0 1.6 1 0 0 1 1 1 1 Velvet factor MOZ_SAS PF01853.13 EDN03727.1 - 7.8e-80 266.5 0.0 1.1e-79 266.0 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Toxin_44 PF15523.1 EDN03728.1 - 0.14 12.0 0.1 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 Putative toxin 44 Acetyltransf_2 PF00797.12 EDN03729.1 - 2.2e-16 60.1 0.0 2.6e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Methyltransf_6 PF03737.10 EDN03730.1 - 3.1e-22 79.0 0.0 4.8e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase AFOR_N PF02730.10 EDN03730.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain Thiolase_N PF00108.18 EDN03731.1 - 6.3e-79 264.6 3.6 1.1e-78 263.9 2.5 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDN03731.1 - 1.7e-44 150.1 0.2 3.2e-44 149.2 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EDN03731.1 - 0.012 15.1 1.3 0.053 12.9 0.3 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 EDN03731.1 - 0.062 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal MFS_1 PF07690.11 EDN03733.1 - 9.7e-13 47.5 20.9 3.7e-11 42.3 9.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Drf_GBD PF06371.8 EDN03734.1 - 7.1e-19 67.8 1.0 2e-11 43.5 0.0 2.6 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Snf7 PF03357.16 EDN03735.1 - 4e-38 130.4 14.4 5.9e-38 129.9 10.0 1.2 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 EDN03735.1 - 0.0018 17.7 5.7 0.0018 17.7 4.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) IncA PF04156.9 EDN03735.1 - 0.3 10.6 6.1 0.53 9.8 0.3 2.2 2 0 0 2 2 2 0 IncA protein Atg14 PF10186.4 EDN03735.1 - 0.65 8.8 8.3 0.93 8.3 5.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SAPS PF04499.10 EDN03736.1 - 1e-175 585.0 0.0 6.1e-175 582.4 0.0 1.9 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Complex1_51K PF01512.12 EDN03738.1 - 3.1e-47 160.0 0.0 4.8e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EDN03738.1 - 5.1e-19 67.1 1.5 5.1e-19 67.1 1.0 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EDN03738.1 - 3.9e-10 39.4 0.0 2.1e-09 37.1 0.0 2.3 2 0 0 2 2 2 1 SLBB domain Nup96 PF12110.3 EDN03739.1 - 9e-92 307.2 0.0 1.3e-91 306.7 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EDN03739.1 - 2.8e-46 156.8 0.0 4.8e-46 156.0 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase TFIIF_alpha PF05793.7 EDN03739.1 - 2.3 6.4 12.2 5 5.3 8.5 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AMP-binding PF00501.23 EDN03741.1 - 7.1e-92 307.9 0.0 9.2e-92 307.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN03741.1 - 3.1e-24 85.6 0.4 1e-20 74.4 0.1 3.0 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain DUF1967 PF09269.6 EDN03741.1 - 0.088 12.4 0.3 1.5 8.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) GET2 PF08690.5 EDN03743.1 - 1.1e-05 24.8 0.1 2.2e-05 23.8 0.1 1.6 1 1 0 1 1 1 1 GET complex subunit GET2 DUF3094 PF11293.3 EDN03743.1 - 0.17 11.4 1.9 0.34 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) C2 PF00168.25 EDN03744.1 - 7e-21 73.8 0.0 8.9e-15 54.3 0.0 2.7 2 0 0 2 2 2 2 C2 domain PFL PF02901.10 EDN03746.1 - 0.003 16.0 1.6 0.003 16.0 1.1 1.4 1 1 1 2 2 2 1 Pyruvate formate lyase DUF3819 PF12842.2 EDN03746.1 - 0.037 13.6 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) DUF3867 PF12983.2 EDN03746.1 - 0.12 12.2 1.2 0.15 12.0 0.8 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3867) DUF3746 PF12562.3 EDN03746.1 - 0.12 12.1 1.6 0.18 11.7 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3746) DUF4404 PF14357.1 EDN03746.1 - 0.19 12.1 1.3 2.4 8.6 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3435 PF11917.3 EDN03747.1 - 3e-167 556.6 0.4 4e-167 556.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EDN03747.1 - 7e-06 25.8 0.1 0.00091 18.9 0.0 2.4 2 0 0 2 2 2 2 Phage integrase family OmpH PF03938.9 EDN03747.1 - 0.41 10.5 8.6 0.43 10.5 0.0 2.7 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Lac_bphage_repr PF06543.7 EDN03749.1 - 0.044 13.3 2.4 0.14 11.6 1.7 1.8 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor NODP PF07684.7 EDN03751.1 - 0.043 13.4 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 NOTCH protein Piwi PF02171.12 EDN03752.1 - 2.8e-70 236.6 0.0 5.2e-70 235.7 0.0 1.5 1 1 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EDN03752.1 - 1.8e-15 56.0 0.1 4.1e-15 54.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EDN03752.1 - 6e-09 35.3 0.1 1.3e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 PAZ domain APH PF01636.18 EDN03754.1 - 4.1e-09 36.5 0.0 5.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EDN03754.1 - 0.0023 17.1 0.0 0.01 15.0 0.0 1.8 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.15 EDN03754.1 - 0.043 13.3 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EDN03754.1 - 0.15 10.6 0.0 0.4 9.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) APH PF01636.18 EDN03755.1 - 0.018 14.7 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ToxN_toxin PF13958.1 EDN03756.1 - 0.12 12.0 0.3 8.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Toxin ToxN, type III toxin-antitoxin system AAA PF00004.24 EDN03757.1 - 1.1e-14 54.7 0.0 1.6e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN03757.1 - 0.00095 19.1 0.0 0.027 14.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EDN03757.1 - 0.0021 17.4 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDN03757.1 - 0.02 13.9 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EDN03757.1 - 0.026 15.3 0.1 0.052 14.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EDN03757.1 - 0.033 14.3 0.2 0.71 10.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.9 EDN03757.1 - 0.11 12.1 0.1 0.54 9.9 0.0 2.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EDN03757.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EDN03757.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TPR_12 PF13424.1 EDN03758.1 - 6.5e-05 22.7 0.2 0.015 15.2 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDN03758.1 - 0.0054 16.3 0.3 2.8 7.6 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.1 EDN03758.1 - 0.017 15.4 0.0 0.057 13.7 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDN03758.1 - 0.022 14.6 0.1 32 4.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EDN03758.1 - 0.064 13.3 0.1 0.18 11.9 0.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EDN03758.1 - 0.074 13.7 0.0 0.27 11.9 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_5 PF12688.2 EDN03758.1 - 0.093 12.7 0.1 2.5 8.1 0.0 2.8 2 0 0 2 2 2 0 Tetratrico peptide repeat BCS1_N PF08740.6 EDN03759.1 - 1.9e-41 141.7 0.0 3.1e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN03759.1 - 1.4e-18 67.3 0.0 3.6e-18 66.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN03759.1 - 0.0014 18.6 0.1 0.0046 16.9 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EDN03759.1 - 0.007 17.1 0.7 0.041 14.7 0.0 2.6 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EDN03759.1 - 0.012 15.0 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDN03759.1 - 0.048 13.3 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN03759.1 - 0.051 13.7 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDN03759.1 - 0.055 13.3 0.1 0.37 10.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EDN03759.1 - 0.063 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 EDN03759.1 - 0.092 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain PPV_E1_C PF00519.12 EDN03759.1 - 0.11 11.1 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase AAA_18 PF13238.1 EDN03759.1 - 0.11 12.7 0.1 21 5.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain Myb_DNA-binding PF00249.26 EDN03760.1 - 3.8e-11 42.8 0.4 7.8e-10 38.6 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN03760.1 - 1.7e-07 31.2 0.9 2.6e-06 27.4 0.1 2.5 1 1 1 2 2 2 1 Myb-like DNA-binding domain DUF1886 PF09171.5 EDN03760.1 - 0.079 11.9 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) DegS PF05384.6 EDN03761.1 - 0.028 13.6 0.3 0.061 12.5 0.1 1.5 2 0 0 2 2 2 0 Sensor protein DegS HALZ PF02183.13 EDN03761.1 - 0.064 12.9 0.1 0.44 10.2 0.2 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Myb_DNA-bind_6 PF13921.1 EDN03762.1 - 0.0012 18.8 0.1 0.0022 18.0 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN03762.1 - 0.033 14.2 0.1 0.069 13.2 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF4244 PF14029.1 EDN03762.1 - 0.036 13.1 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) Ndc1_Nup PF09531.5 EDN03763.1 - 0.46 8.8 1.5 0.6 8.4 1.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nucleoplasmin PF03066.10 EDN03764.1 - 0.00058 19.4 3.5 0.00062 19.2 2.4 1.2 1 0 0 1 1 1 1 Nucleoplasmin Myc_N PF01056.13 EDN03764.1 - 0.0053 15.9 7.0 0.0075 15.4 4.8 1.2 1 0 0 1 1 1 1 Myc amino-terminal region BSP_II PF05432.6 EDN03764.1 - 0.015 14.6 10.5 0.019 14.2 7.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TFIIF_alpha PF05793.7 EDN03764.1 - 0.019 13.3 11.3 0.019 13.3 7.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) VID27 PF08553.5 EDN03764.1 - 0.02 13.1 6.6 0.023 12.9 4.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF1510 PF07423.6 EDN03764.1 - 0.021 14.1 7.9 0.03 13.6 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Merozoite_SPAM PF07133.6 EDN03764.1 - 0.044 13.6 17.2 0.077 12.8 11.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop14 PF04147.7 EDN03764.1 - 0.046 11.6 6.8 0.043 11.7 4.7 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_60s PF00428.14 EDN03764.1 - 0.052 13.9 12.4 0.1 12.9 8.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein PBP1_TM PF14812.1 EDN03764.1 - 0.075 13.3 7.2 0.16 12.3 5.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FimP PF09766.4 EDN03764.1 - 0.077 12.0 3.3 0.1 11.6 2.3 1.2 1 0 0 1 1 1 0 Fms-interacting protein Tim54 PF11711.3 EDN03764.1 - 0.1 11.1 3.8 0.15 10.6 2.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_polI_A34 PF08208.6 EDN03764.1 - 0.16 11.6 9.8 0.24 11.0 6.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 NOA36 PF06524.7 EDN03764.1 - 0.17 11.1 3.2 0.17 11.0 2.2 1.2 1 0 0 1 1 1 0 NOA36 protein SelP_N PF04592.9 EDN03764.1 - 0.18 11.1 3.0 0.26 10.6 2.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Lar_restr_allev PF14354.1 EDN03764.1 - 0.23 11.7 1.6 0.39 11.0 0.0 2.2 2 1 0 2 2 2 0 Restriction alleviation protein Lar RR_TM4-6 PF06459.7 EDN03764.1 - 0.55 10.0 10.3 0.69 9.7 7.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TRAP_alpha PF03896.11 EDN03764.1 - 0.56 9.1 5.7 0.74 8.7 3.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4407 PF14362.1 EDN03764.1 - 0.72 8.7 3.2 0.8 8.6 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VIT1 PF01988.14 EDN03764.1 - 0.76 9.2 5.1 1 8.7 3.5 1.2 1 0 0 1 1 1 0 VIT family Nucleo_P87 PF07267.6 EDN03764.1 - 0.83 8.2 6.2 0.82 8.2 4.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SLAIN PF15301.1 EDN03764.1 - 1.3 8.0 8.7 1.9 7.6 6.0 1.2 1 0 0 1 1 1 0 SLAIN motif-containing family Ycf1 PF05758.7 EDN03764.1 - 2.1 5.9 5.4 3.1 5.4 3.7 1.2 1 0 0 1 1 1 0 Ycf1 Prog_receptor PF02161.10 EDN03764.1 - 2.4 6.9 6.9 3.2 6.4 4.8 1.2 1 0 0 1 1 1 0 Progesterone receptor FYDLN_acid PF09538.5 EDN03764.1 - 2.5 8.7 11.8 0.22 12.1 4.9 1.6 2 0 0 2 2 1 0 Protein of unknown function (FYDLN_acid) NARP1 PF12569.3 EDN03764.1 - 2.6 6.7 6.8 3.1 6.4 4.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TORC_M PF12885.2 EDN03764.1 - 3.6 7.3 6.0 19 4.9 4.0 1.9 1 1 1 2 2 2 0 Transducer of regulated CREB activity middle domain RNase_H2-Ydr279 PF09468.5 EDN03764.1 - 7 5.7 6.9 9.4 5.3 4.8 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RNA_pol_Rpc4 PF05132.9 EDN03764.1 - 7.3 6.5 9.5 14 5.6 6.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF788 PF05620.6 EDN03764.1 - 8 6.2 7.8 12 5.7 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF2841 PF11001.3 EDN03767.1 - 2.1e-47 160.1 0.4 2.9e-47 159.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Lac_bphage_repr PF06543.7 EDN03768.1 - 0.16 11.4 2.0 0.34 10.4 1.4 1.5 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor AAA_assoc PF14363.1 EDN03769.1 - 0.027 14.5 0.1 0.037 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA RVT_2 PF07727.9 EDN03770.1 - 1.9e-66 223.5 0.0 1.1e-56 191.5 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN03770.1 - 1.7e-11 44.2 0.0 4.2e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN03770.1 - 6.5e-06 25.6 0.0 1.9e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain Pkinase PF00069.20 EDN03771.1 - 1.7e-13 50.3 0.2 7.9e-12 44.8 0.1 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN03771.1 - 1.1e-08 34.5 0.1 2.2e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase YgaB PF14182.1 EDN03773.1 - 0.049 13.8 1.6 0.32 11.2 0.2 2.3 1 1 1 2 2 2 0 YgaB-like protein KRAB PF01352.22 EDN03773.1 - 0.19 11.1 2.7 7.4 6.1 0.0 2.3 2 0 0 2 2 2 0 KRAB box FAD_binding_8 PF08022.7 EDN03776.1 - 9.8e-16 57.5 0.0 2.1e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EDN03776.1 - 1e-07 32.0 10.5 3.5e-07 30.3 7.3 1.9 1 1 0 1 1 1 1 Ferric reductase like transmembrane component CDP-OH_P_tran_2 PF08009.6 EDN03776.1 - 0.049 13.3 0.8 0.14 11.8 0.6 1.8 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 DUF3723 PF12520.3 EDN03777.1 - 6.7e-85 285.4 0.0 5.5e-72 242.8 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF3723) Patatin PF01734.17 EDN03778.1 - 0.0001 22.2 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Sgf11 PF08209.6 EDN03778.1 - 0.18 11.1 4.0 0.23 10.8 0.2 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) C1_1 PF00130.17 EDN03780.1 - 0.00012 21.7 2.9 0.00012 21.7 2.0 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.1 EDN03780.1 - 0.06 12.9 6.7 0.7 9.5 0.5 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Syntaxin PF00804.20 EDN03780.1 - 0.091 12.9 1.2 7.6 6.7 0.1 3.5 3 0 0 3 3 3 0 Syntaxin FYVE_2 PF02318.11 EDN03780.1 - 0.11 12.3 3.5 0.27 11.1 2.4 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Ta0938 PF11494.3 EDN03780.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 Ta0938 zf-C3HC4_3 PF13920.1 EDN03780.1 - 1.2 8.8 7.2 0.4 10.3 1.0 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EDN03780.1 - 2.2 8.0 7.3 5.1 6.8 5.0 1.7 1 0 0 1 1 1 0 PHD-finger Radial_spoke PF04712.7 EDN03784.1 - 0.0015 17.3 8.6 0.0015 17.3 5.9 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein Spore_coat_CotO PF14153.1 EDN03784.1 - 0.01 15.3 2.9 0.0089 15.4 2.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Sigma70_ner PF04546.8 EDN03784.1 - 0.019 14.6 6.0 0.022 14.4 4.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 EDN03784.1 - 0.025 14.3 5.1 0.032 14.0 3.5 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_Ag35 PF03286.9 EDN03784.1 - 0.049 13.1 5.0 0.058 12.9 3.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PAXIP1_C PF15364.1 EDN03784.1 - 0.075 12.9 5.2 0.093 12.6 3.6 1.2 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Vfa1 PF08432.5 EDN03784.1 - 0.1 12.6 3.2 0.11 12.4 2.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 EDN03784.1 - 0.14 10.6 13.6 0.14 10.5 9.4 1.0 1 0 0 1 1 1 0 Daxx Family Pox_RNA_Pol_19 PF05320.7 EDN03784.1 - 0.14 11.9 4.3 0.2 11.4 3.0 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DAP PF15228.1 EDN03784.1 - 0.16 12.7 0.8 0.22 12.2 0.5 1.3 1 0 0 1 1 1 0 Death-associated protein FAM176 PF14851.1 EDN03784.1 - 0.19 11.3 4.9 0.26 10.9 3.4 1.2 1 0 0 1 1 1 0 FAM176 family Sigma70_r1_1 PF03979.9 EDN03784.1 - 0.23 11.4 16.1 5.5 7.0 10.8 2.2 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 TRAP_alpha PF03896.11 EDN03784.1 - 0.47 9.4 6.4 0.51 9.2 4.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BSP_II PF05432.6 EDN03784.1 - 0.58 9.3 17.8 0.75 9.0 12.4 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Adeno_terminal PF02459.10 EDN03784.1 - 0.59 8.2 9.2 0.71 7.9 6.4 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Prothymosin PF03247.9 EDN03784.1 - 0.84 9.8 24.9 1.2 9.3 17.2 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF2890 PF11081.3 EDN03784.1 - 1.1 9.3 14.5 1.3 9.0 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) RNA_pol_Rpc4 PF05132.9 EDN03784.1 - 1.1 9.2 4.8 1.4 8.8 3.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Paf1 PF03985.8 EDN03784.1 - 1.2 7.8 14.0 1.4 7.5 9.7 1.1 1 0 0 1 1 1 0 Paf1 DUF2457 PF10446.4 EDN03784.1 - 1.4 7.5 14.2 1.9 7.1 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FCP1_C PF09309.5 EDN03784.1 - 1.4 8.1 12.4 1.8 7.7 8.6 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Nucleoplasmin PF03066.10 EDN03784.1 - 1.6 8.2 17.2 2.1 7.8 11.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin BTV_NS2 PF04514.7 EDN03784.1 - 1.6 7.5 7.1 1.9 7.3 4.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CENP-B_dimeris PF09026.5 EDN03784.1 - 1.8 8.8 14.1 3.1 8.0 9.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 EDN03784.1 - 1.8 6.4 8.3 2.1 6.2 5.7 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.3 EDN03784.1 - 1.9 8.3 20.2 0.13 12.1 10.4 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.7 EDN03784.1 - 2 6.1 14.4 2.4 5.9 10.0 1.0 1 0 0 1 1 1 0 Nop14-like family Ycf1 PF05758.7 EDN03784.1 - 2.3 5.8 5.8 2.6 5.6 4.0 1.0 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 EDN03784.1 - 3.4 6.9 11.0 4 6.7 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4337 PF14235.1 EDN03784.1 - 5.1 6.9 5.6 6.9 6.4 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Prog_receptor PF02161.10 EDN03784.1 - 5.3 5.7 6.5 5.6 5.6 4.5 1.1 1 0 0 1 1 1 0 Progesterone receptor DNA_pol_phi PF04931.8 EDN03784.1 - 7.5 4.1 16.6 8.3 4.0 11.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF740 PF05340.7 EDN03784.1 - 7.5 4.7 10.0 8.7 4.5 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) YqfQ PF14181.1 EDN03784.1 - 7.5 6.5 7.1 10 6.1 4.9 1.2 1 0 0 1 1 1 0 YqfQ-like protein IMS PF00817.15 EDN03785.1 - 1.4e-37 128.8 0.0 2.2e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EDN03785.1 - 0.00017 21.5 1.0 0.00084 19.2 0.4 2.3 2 1 0 2 2 2 1 impB/mucB/samB family C-terminal domain Sigma70_ner PF04546.8 EDN03785.1 - 0.05 13.2 6.0 0.78 9.3 2.1 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4611 PF15387.1 EDN03785.1 - 0.075 13.1 8.5 0.078 13.1 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TRAP_alpha PF03896.11 EDN03785.1 - 0.091 11.7 4.6 0.68 8.8 0.2 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 EDN03785.1 - 7.7 6.0 16.2 8.5 5.8 0.2 2.3 2 0 0 2 2 2 0 Nucleoplasmin DUF4453 PF14627.1 EDN03786.1 - 0.0041 17.2 0.5 0.0088 16.1 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4453) Pep_M12B_propep PF01562.14 EDN03786.1 - 0.0083 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide Disintegrin PF00200.18 EDN03787.1 - 3e-19 69.0 34.5 3e-19 69.0 23.9 3.6 2 1 0 2 2 2 1 Disintegrin DUF1191 PF06697.7 EDN03787.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EF-hand_7 PF13499.1 EDN03788.1 - 5.5e-15 55.2 0.1 1.5e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EDN03788.1 - 2.1e-14 51.6 2.2 3.4e-05 22.8 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EDN03788.1 - 4.9e-14 50.8 5.1 4.8e-06 26.0 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EDN03788.1 - 2.7e-11 42.8 2.4 5e-09 35.6 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EDN03788.1 - 0.043 13.1 8.2 0.3 10.5 0.5 2.9 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.2 EDN03788.1 - 0.089 12.5 0.0 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Metal_resist PF13801.1 EDN03788.1 - 8.5 6.3 11.5 0.28 11.1 0.5 2.9 2 1 1 3 3 3 0 Heavy-metal resistance MgsA_C PF12002.3 EDN03789.1 - 2.6e-57 193.1 0.0 4.7e-57 192.3 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EDN03789.1 - 1.5e-13 51.1 0.1 3.5e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDN03789.1 - 7.2e-10 38.3 0.0 2.4e-09 36.6 0.0 1.6 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EDN03789.1 - 2.9e-05 23.7 0.0 6.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 EDN03789.1 - 4.3e-05 23.0 0.1 0.0023 17.4 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EDN03789.1 - 4.4e-05 23.2 0.1 0.0027 17.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EDN03789.1 - 5.1e-05 22.5 0.1 0.053 12.6 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EDN03789.1 - 0.00088 19.4 0.2 0.0048 17.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDN03789.1 - 0.00088 19.1 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EDN03789.1 - 0.0013 18.3 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EDN03789.1 - 0.0014 18.6 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.8 EDN03789.1 - 0.0028 16.4 0.1 0.01 14.5 0.1 1.8 1 1 1 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 EDN03789.1 - 0.004 16.1 0.0 0.0065 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EDN03789.1 - 0.0043 17.8 0.0 0.017 15.9 0.0 1.9 1 1 0 2 2 1 1 AAA domain ResIII PF04851.10 EDN03789.1 - 0.0049 16.7 0.2 1.5 8.6 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EDN03789.1 - 0.011 15.9 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EDN03789.1 - 0.016 15.1 0.0 0.42 10.5 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 EDN03789.1 - 0.03 13.9 0.3 0.11 12.0 0.3 1.8 1 1 1 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EDN03789.1 - 0.04 12.7 0.0 0.2 10.5 0.0 2.1 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 SKI PF01202.17 EDN03789.1 - 0.043 13.6 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase NB-ARC PF00931.17 EDN03789.1 - 0.066 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Sgf11 PF08209.6 EDN03789.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Aminotran_1_2 PF00155.16 EDN03790.1 - 5.1e-57 193.4 0.0 1.3e-56 192.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EDN03790.1 - 0.003 16.6 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family KH_1 PF00013.24 EDN03791.1 - 5.3e-42 141.2 15.1 2e-15 56.1 1.1 3.7 3 1 1 4 4 4 3 KH domain KH_3 PF13014.1 EDN03791.1 - 3e-33 112.8 14.3 5.4e-11 41.8 0.5 4.9 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 EDN03791.1 - 2.9e-13 49.1 2.3 0.0016 17.9 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EDN03791.1 - 6.6e-10 38.4 1.0 0.013 15.0 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EDN03791.1 - 0.00033 20.3 3.4 4.9 7.0 0.1 3.6 3 0 0 3 3 3 3 NusA-like KH domain Ald_Xan_dh_C2 PF02738.13 EDN03794.1 - 2.9e-193 643.1 0.1 4e-193 642.6 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EDN03794.1 - 5.7e-47 159.3 0.0 1.1e-46 158.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EDN03794.1 - 1.4e-32 111.7 0.0 4.3e-32 110.1 0.0 1.9 1 0 0 1 1 1 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 EDN03794.1 - 9.6e-29 99.1 0.1 2.1e-28 98.0 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.17 EDN03794.1 - 8.2e-26 90.2 0.0 1.9e-25 89.1 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.22 EDN03794.1 - 2.1e-09 36.9 1.3 3.8e-09 36.1 0.1 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.12 EDN03794.1 - 0.016 14.7 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 DUF218 domain Syndecan PF01034.15 EDN03797.1 - 0.026 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain SCIMP PF15050.1 EDN03797.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 SCIMP protein AAA_17 PF13207.1 EDN03798.1 - 0.00067 20.4 0.0 0.0014 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDN03798.1 - 0.0053 17.0 0.0 0.028 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EDN03798.1 - 0.0061 16.8 0.1 0.012 15.9 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EDN03798.1 - 0.0087 15.5 0.1 0.026 14.0 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EDN03798.1 - 0.021 15.1 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EDN03798.1 - 0.021 14.3 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 EDN03798.1 - 0.077 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.15 EDN03798.1 - 0.079 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_28 PF13521.1 EDN03798.1 - 0.089 12.7 0.1 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EDN03799.1 - 2.1e-38 131.7 0.0 9.2e-34 116.5 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN03799.1 - 0.0003 20.5 0.0 0.0006 19.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HMG_box PF00505.14 EDN03800.1 - 1.5e-23 82.7 0.3 2.7e-23 82.0 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDN03800.1 - 1.4e-08 35.0 0.1 3.5e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain Ribosomal_S6e PF01092.14 EDN03801.1 - 3.1e-59 198.1 0.6 5.9e-59 197.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e Pribosyl_synth PF14572.1 EDN03802.1 - 8.7e-33 113.6 6.4 3.8e-26 91.9 3.2 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EDN03802.1 - 6.8e-28 96.7 3.8 3.2e-26 91.3 0.2 3.6 2 2 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EDN03802.1 - 2.8e-12 46.4 0.4 6.6e-12 45.2 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EDN03802.1 - 0.00076 18.7 0.5 0.0012 18.0 0.3 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF218 PF02698.12 EDN03802.1 - 0.12 11.8 0.1 0.39 10.1 0.0 1.8 1 1 0 1 1 1 0 DUF218 domain DUF913 PF06025.7 EDN03803.1 - 1.6e-138 461.6 0.0 1.6e-138 461.6 0.0 3.8 4 1 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 EDN03803.1 - 5.5e-86 288.8 0.3 5.5e-86 288.8 0.2 2.9 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) HECT PF00632.20 EDN03803.1 - 6.4e-81 271.9 0.1 1.1e-80 271.1 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.1 EDN03803.1 - 2.7e-35 120.5 6.6 2.7e-35 120.5 4.6 4.1 3 1 0 3 3 3 1 Domain of unknown function (DUF4414) An_peroxidase PF03098.10 EDN03804.1 - 8.1e-51 172.9 0.0 3e-41 141.4 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 EDN03804.1 - 6.2e-06 24.9 0.0 1.4e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 Steroid_dh PF02544.11 EDN03805.1 - 8.5e-24 84.0 0.0 1e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EDN03805.1 - 4e-05 23.6 0.2 6.3e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 EDN03805.1 - 0.00051 19.4 0.1 0.00061 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Glyco_transf_34 PF05637.7 EDN03806.1 - 8.6e-60 202.2 0.0 1.1e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Ribosomal_L28 PF00830.14 EDN03807.1 - 4.4e-19 68.0 1.5 4.4e-19 68.0 1.0 1.9 2 0 0 2 2 2 1 Ribosomal L28 family TIP49 PF06068.8 EDN03808.1 - 3.9e-179 595.5 0.4 6.7e-131 436.6 0.1 2.0 2 0 0 2 2 2 2 TIP49 C-terminus AAA PF00004.24 EDN03808.1 - 4.5e-10 39.8 0.1 2.5e-07 30.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDN03808.1 - 9.2e-10 37.9 0.1 3.8e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EDN03808.1 - 7e-05 22.5 0.1 0.0002 21.0 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EDN03808.1 - 0.00022 21.2 0.0 0.0063 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 EDN03808.1 - 0.00023 21.1 0.1 0.00049 20.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDN03808.1 - 0.0017 17.5 0.4 0.0038 16.3 0.3 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EDN03808.1 - 0.003 17.0 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDN03808.1 - 0.021 14.9 0.0 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EDN03808.1 - 0.031 13.6 0.1 0.057 12.8 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 EDN03808.1 - 0.039 13.0 0.2 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 KaiC DUF2075 PF09848.4 EDN03808.1 - 0.041 12.8 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EDN03808.1 - 0.055 13.7 0.1 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.10 EDN03808.1 - 0.065 12.1 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.1 EDN03808.1 - 0.066 14.0 0.1 0.19 12.5 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_5 PF07728.9 EDN03808.1 - 0.074 12.7 0.1 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.11 EDN03808.1 - 0.25 10.5 1.2 0.32 10.1 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein NAD_binding_8 PF13450.1 EDN03809.1 - 2.9e-10 40.0 0.1 6.4e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EDN03809.1 - 1.6e-06 27.5 0.0 0.00039 19.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 EDN03809.1 - 4e-06 25.9 0.5 2.1e-05 23.6 0.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EDN03809.1 - 1.7e-05 24.9 0.1 0.0005 20.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN03809.1 - 0.00014 22.2 0.1 0.00099 19.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN03809.1 - 0.00016 20.8 0.0 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EDN03809.1 - 0.00051 19.9 0.0 0.002 18.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDN03809.1 - 0.00075 18.6 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FMO-like PF00743.14 EDN03809.1 - 0.0015 16.8 0.0 0.0022 16.2 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like HI0933_like PF03486.9 EDN03809.1 - 0.0016 17.0 0.0 0.0055 15.2 0.0 1.9 2 1 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EDN03809.1 - 0.0025 17.5 0.0 0.024 14.4 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 EDN03809.1 - 0.013 14.3 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EDN03809.1 - 0.019 13.8 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FANCI_HD1 PF14679.1 EDN03809.1 - 0.03 14.0 0.2 0.08 12.6 0.1 1.7 1 0 0 1 1 1 0 FANCI helical domain 1 Vint PF14623.1 EDN03809.1 - 0.034 13.6 0.1 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Hint-domain IlvN PF07991.7 EDN03809.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_C PF01262.16 EDN03809.1 - 0.14 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain V-SNARE PF05008.10 EDN03810.1 - 2.6e-21 75.5 6.2 2.6e-21 75.5 4.3 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EDN03810.1 - 2.1e-15 56.5 3.2 2.1e-15 56.5 2.2 2.5 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EDN03810.1 - 0.0021 17.7 1.8 0.0036 16.9 0.1 2.1 2 0 0 2 2 2 1 Sec20 ApoLp-III PF07464.6 EDN03810.1 - 0.019 15.0 3.9 0.2 11.6 2.1 2.3 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Phe_tRNA-synt_N PF02912.13 EDN03810.1 - 0.065 12.9 2.1 7.1 6.4 1.0 2.5 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain YvbH_ext PF11724.3 EDN03810.1 - 0.072 12.7 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 YvbH-like oligomerisation region Fusion_gly PF00523.13 EDN03810.1 - 0.25 9.3 3.3 0.59 8.1 0.1 2.3 2 1 0 2 2 2 0 Fusion glycoprotein F0 Histone_HNS PF00816.16 EDN03810.1 - 2 8.9 7.2 0.23 11.9 1.7 1.8 2 0 0 2 2 2 0 H-NS histone family ZapA PF05164.8 EDN03810.1 - 4 7.4 8.9 1.4 8.9 0.1 3.6 2 1 0 2 2 2 0 Cell division protein ZapA DUF607 PF04678.8 EDN03810.1 - 4.5 7.1 5.4 0.65 9.9 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF607 DUF501 PF04417.7 EDN03810.1 - 5.1 6.9 5.5 1.3 8.9 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF501) DUF2407_C PF13373.1 EDN03811.1 - 2.1e-39 134.6 0.1 3.1e-39 134.0 0.1 1.3 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EDN03811.1 - 2.8e-33 113.9 0.0 5.5e-33 113.0 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EDN03811.1 - 0.00094 18.5 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family PAP1 PF08601.5 EDN03811.1 - 0.091 12.4 2.4 0.11 12.1 1.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Rad60-SLD_2 PF13881.1 EDN03811.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Fe-S_biosyn PF01521.15 EDN03812.1 - 2.4e-20 72.5 0.0 3.3e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Nucleic_acid_bd PF13820.1 EDN03812.1 - 0.062 12.8 0.4 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Putative nucleic acid-binding region DUF4527 PF15030.1 EDN03812.1 - 0.079 12.2 4.0 0.11 11.8 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) DUF605 PF04652.11 EDN03812.1 - 7.6 5.8 19.9 9.6 5.4 13.8 1.1 1 0 0 1 1 1 0 Vta1 like DUF1741 PF08427.5 EDN03813.1 - 4.9e-98 327.3 1.0 1e-97 326.2 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) MRG PF05712.8 EDN03814.1 - 3.8e-56 189.1 0.2 5.5e-56 188.5 0.2 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EDN03814.1 - 7.8e-09 35.1 3.3 2.2e-08 33.6 2.3 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EDN03814.1 - 0.2 11.3 3.4 0.23 11.1 1.1 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Cnl2_NKP2 PF09447.5 EDN03815.1 - 1.2e-28 98.5 0.5 1.9e-28 97.9 0.4 1.3 1 0 0 1 1 1 1 Cnl2/NKP2 family protein Ctf8 PF09696.5 EDN03817.1 - 3.3e-45 152.7 0.0 6.5e-45 151.8 0.0 1.4 1 1 0 1 1 1 1 Ctf8 Glyoxalase PF00903.20 EDN03818.1 - 7.6e-17 61.4 0.0 2.6e-14 53.2 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EDN03818.1 - 9.1e-13 48.1 0.0 9.4e-06 25.6 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EDN03818.1 - 1.1e-07 32.4 0.0 0.00015 22.3 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EDN03818.1 - 4.2e-06 26.7 0.0 0.46 10.3 0.0 3.5 4 0 0 4 4 4 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EDN03818.1 - 2e-05 24.5 0.0 0.0059 16.5 0.0 3.1 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal RabGAP-TBC PF00566.13 EDN03819.1 - 2.9e-49 167.4 0.1 2.9e-49 167.4 0.1 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Microtub_assoc PF07989.6 EDN03819.1 - 0.053 13.3 19.1 0.26 11.1 1.7 3.6 2 1 2 4 4 4 0 Microtubule associated Med9 PF07544.8 EDN03819.1 - 1.8 8.3 9.1 0.17 11.6 0.4 3.5 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Tho2 PF11262.3 EDN03819.1 - 4.6 6.1 6.5 8.4 5.3 4.5 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF972 PF06156.8 EDN03819.1 - 7.6 6.9 16.2 19 5.6 5.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PPTA PF01239.17 EDN03820.1 - 2.8e-31 105.5 12.0 5.8e-07 28.5 0.0 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Trns_repr_metal PF02583.12 EDN03820.1 - 0.099 12.8 0.7 0.4 10.9 0.1 2.3 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor Utp12 PF04003.7 EDN03823.1 - 2.1e-20 72.6 0.1 3.6e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family CENP-T PF15511.1 EDN03823.1 - 1.4 8.0 46.7 2.2 7.4 7.3 2.2 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Bromodomain PF00439.20 EDN03825.1 - 5.6e-40 135.1 0.2 1.2e-21 76.3 0.2 2.6 2 0 0 2 2 2 2 Bromodomain DUF3573 PF12097.3 EDN03825.1 - 0.0065 15.1 3.8 0.01 14.4 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) DUF812 PF05667.6 EDN03825.1 - 0.007 14.9 6.0 0.012 14.1 4.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) HeLo PF14479.1 EDN03825.1 - 0.064 13.0 5.3 0.17 11.6 3.7 1.7 1 0 0 1 1 1 0 Prion-inhibition and propagation DUF1631 PF07793.6 EDN03825.1 - 0.15 10.1 2.9 0.3 9.1 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Sulfate_transp PF00916.15 EDN03826.1 - 5.4e-40 137.1 9.2 7.5e-40 136.6 6.4 1.2 1 0 0 1 1 1 1 Sulfate transporter family HMG_box PF00505.14 EDN03827.1 - 1.3e-11 44.5 0.9 2.4e-11 43.7 0.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box MAT_Alpha1 PF04769.7 EDN03827.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 PHD PF00628.24 EDN03831.1 - 4.9e-10 38.9 8.5 1.2e-09 37.6 5.9 1.8 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EDN03831.1 - 8.4e-05 21.7 4.0 8.4e-05 21.7 2.8 2.2 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 EDN03831.1 - 3.4 7.4 6.8 0.48 10.1 1.9 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Rcd1 PF04078.8 EDN03832.1 - 8.4e-131 434.5 2.8 1.2e-130 434.0 2.0 1.2 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like FRQ PF09421.5 EDN03832.1 - 0.0067 14.2 4.7 0.009 13.8 3.2 1.3 1 0 0 1 1 1 1 Frequency clock protein Ycf1 PF05758.7 EDN03832.1 - 0.0093 13.7 0.1 0.014 13.1 0.1 1.3 2 0 0 2 2 2 1 Ycf1 MAT1 PF06391.8 EDN03832.1 - 0.13 11.8 8.7 0.19 11.2 6.0 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 TFIIA PF03153.8 EDN03832.1 - 0.14 12.0 26.2 0.2 11.5 18.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BRF1 PF07741.8 EDN03832.1 - 0.68 10.1 10.3 1.7 8.8 7.2 1.8 1 0 0 1 1 1 0 Brf1-like TBP-binding domain PAT1 PF09770.4 EDN03832.1 - 0.85 7.7 29.6 1 7.5 20.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HA2 PF04408.18 EDN03832.1 - 1.3 9.1 5.4 1.4 8.9 1.8 2.5 1 1 1 2 2 2 0 Helicase associated domain (HA2) DUF4175 PF13779.1 EDN03832.1 - 1.4 6.5 26.1 1.9 6.0 18.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med15 PF09606.5 EDN03832.1 - 1.5 6.9 42.9 1.8 6.6 29.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 EDN03832.1 - 1.8 7.8 9.8 3.3 7.0 6.8 1.4 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 EDN03832.1 - 5.6 6.5 13.1 9.2 5.8 9.1 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 EDN03832.1 - 9.2 3.7 13.7 53 1.2 9.0 1.9 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein MFS_1 PF07690.11 EDN03835.1 - 5.6e-32 110.8 36.6 1.2e-31 109.7 25.4 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN03835.1 - 8.1e-14 51.0 5.2 8.1e-14 51.0 3.6 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EDN03835.1 - 4.1e-10 38.5 10.8 5.9e-10 37.9 7.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Trypsin PF00089.21 EDN03836.1 - 4.8e-09 36.1 0.3 2.6e-08 33.7 0.1 2.0 1 1 1 2 2 2 1 Trypsin SUI1 PF01253.17 EDN03838.1 - 1.6e-16 59.9 0.0 3.6e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Kin17_mid PF10357.4 EDN03838.1 - 0.0055 16.3 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein Fungal_trans PF04082.13 EDN03839.1 - 7.6e-18 64.3 0.5 1.4e-17 63.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN03839.1 - 6.8e-09 35.4 7.2 1.6e-08 34.2 5.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERG4_ERG24 PF01222.12 EDN03840.1 - 1.5e-133 445.4 18.5 1.7e-133 445.2 12.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Velvet PF11754.3 EDN03843.1 - 7.7e-65 218.3 0.0 1.3e-64 217.5 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Pox_A_type_inc PF04508.7 EDN03844.1 - 0.083 12.7 2.6 0.26 11.1 1.8 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF4094 PF13334.1 EDN03844.1 - 2.4 8.6 6.3 0.57 10.5 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) MFS_1 PF07690.11 EDN03845.1 - 4.6e-33 114.4 25.3 4.6e-33 114.4 17.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 EDN03846.1 - 5.6e-66 222.1 0.0 7.4e-66 221.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDN03846.1 - 3.8e-07 29.5 0.0 1.8e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 EDN03846.1 - 6.5e-07 28.3 0.0 1e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EDN03846.1 - 4.9e-05 23.1 0.0 8.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EDN03846.1 - 0.00028 19.7 0.6 0.00097 17.9 0.4 1.7 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.4 EDN03846.1 - 0.058 12.6 0.7 0.17 11.0 0.1 1.9 1 1 1 2 2 2 0 Esterase PHB depolymerase DHDPS PF00701.17 EDN03848.1 - 7.7e-41 139.5 0.0 1e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Ribonuc_L-PSP PF01042.16 EDN03849.1 - 1.5e-38 131.2 0.0 1.7e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP D-ser_dehydrat PF14031.1 EDN03850.1 - 4.5e-25 87.6 0.0 8.1e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EDN03850.1 - 1.5e-15 57.4 0.0 2.3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Pyridox_oxase_2 PF12766.2 EDN03851.1 - 0.005 17.1 0.0 0.013 15.8 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3007 PF11460.3 EDN03851.1 - 0.024 14.7 0.3 0.071 13.1 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) DUF438 PF04282.8 EDN03851.1 - 0.13 12.0 0.6 0.99 9.2 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF438) Cyclase PF04199.8 EDN03852.1 - 1.9e-13 50.4 0.0 3.3e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase AA_permease_2 PF13520.1 EDN03853.1 - 1.7e-45 155.3 47.0 1.7e-37 128.9 13.7 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 EDN03853.1 - 7.9e-26 90.4 41.1 2.2e-22 79.0 28.5 2.0 1 1 0 1 1 1 1 Amino acid permease JmjC PF02373.17 EDN03856.1 - 3e-38 130.5 0.5 5.2e-38 129.7 0.4 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Carn_acyltransf PF00755.15 EDN03857.1 - 1.8e-144 482.0 0.3 1.8e-107 359.8 0.0 3.0 3 0 0 3 3 3 3 Choline/Carnitine o-acyltransferase PFL PF02901.10 EDN03859.1 - 0.0029 16.1 1.6 0.0029 16.1 1.1 1.5 1 1 1 2 2 2 1 Pyruvate formate lyase GCR1_C PF12550.3 EDN03859.1 - 0.16 11.8 0.9 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Latarcin PF10279.4 EDN03859.1 - 0.73 10.0 4.1 1.8 8.7 2.8 1.9 1 1 0 1 1 1 0 Latarcin precursor AA_permease_2 PF13520.1 EDN03860.1 - 5.2e-67 226.2 40.7 2.1e-34 118.7 10.1 2.4 1 1 1 2 2 2 2 Amino acid permease C5-epim_C PF06662.8 EDN03862.1 - 0.022 14.0 0.1 4.1 6.6 0.0 2.6 3 0 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus CPSase_L_D3 PF02787.14 EDN03862.1 - 0.05 13.3 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Glyco_hydro_88 PF07470.8 EDN03862.1 - 0.13 11.2 0.0 6.6 5.6 0.0 3.0 3 1 1 4 4 4 0 Glycosyl Hydrolase Family 88 DUF2805 PF10985.3 EDN03862.1 - 1.4 8.9 0.0 1.4 8.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2805) Thioredox_DsbH PF03190.10 EDN03863.1 - 5.9e-70 234.2 0.0 7.3e-70 233.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EDN03863.1 - 8e-09 35.4 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EDN03863.1 - 0.027 14.6 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain WD40 PF00400.27 EDN03864.1 - 1.2e-17 63.0 20.6 5.5e-06 26.0 0.7 6.2 5 1 0 5 5 5 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EDN03864.1 - 0.025 14.0 0.4 1.9 7.9 0.1 2.2 2 0 0 2 2 2 0 PQQ-like domain Reg_prop PF07494.6 EDN03864.1 - 0.035 14.0 0.1 1.9 8.7 0.0 2.9 2 0 0 2 2 2 0 Two component regulator propeller Nup160 PF11715.3 EDN03864.1 - 0.046 11.8 4.5 0.46 8.5 0.2 2.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF771 PF05595.6 EDN03864.1 - 0.088 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF771) LSM14 PF12701.2 EDN03865.1 - 2.4e-31 107.3 0.1 5.5e-29 99.8 0.0 2.5 1 1 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EDN03865.1 - 2.9e-22 79.1 3.1 9.3e-22 77.5 2.1 1.9 1 0 0 1 1 1 1 FDF domain KIAA1328 PF15369.1 EDN03865.1 - 2.9 7.6 3.7 4.8 6.8 2.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 ACBP PF00887.14 EDN03866.1 - 6.9e-27 92.9 0.0 1.5e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein eIF-3c_N PF05470.7 EDN03866.1 - 0.067 11.2 11.8 0.098 10.7 8.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2456 PF10445.4 EDN03866.1 - 0.13 12.1 1.1 0.22 11.4 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) Nop14 PF04147.7 EDN03866.1 - 1.4 6.7 22.6 2 6.2 15.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EDN03866.1 - 2.3 6.1 22.4 3.3 5.6 15.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EDN03866.1 - 6.6 5.0 17.7 12 4.2 12.3 1.4 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 EDN03866.1 - 7 5.2 35.5 0.24 10.0 20.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Pox_RNA_Pol_19 PF05320.7 EDN03866.1 - 7.1 6.3 8.4 13 5.4 5.8 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CHCH PF06747.8 EDN03868.1 - 8.8e-09 35.0 11.6 1e-06 28.4 3.5 2.4 2 0 0 2 2 2 2 CHCH domain Pet191_N PF10203.4 EDN03868.1 - 0.013 15.5 10.4 0.049 13.6 1.2 3.0 1 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EDN03868.1 - 0.077 13.0 10.3 0.92 9.5 0.6 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 EDN03868.1 - 0.13 12.0 13.0 0.22 11.3 3.0 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Prefoldin PF02996.12 EDN03870.1 - 4.9e-22 77.8 0.0 9e-22 76.9 0.0 1.4 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EDN03870.1 - 0.025 14.3 0.3 2.7 7.8 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit Prefoldin_3 PF13758.1 EDN03870.1 - 0.065 13.0 0.1 0.14 11.9 0.1 1.7 1 1 0 1 1 1 0 Prefoldin subunit YscO PF07321.7 EDN03870.1 - 0.67 9.7 3.3 9.5 6.0 0.2 2.2 2 0 0 2 2 2 0 Type III secretion protein YscO tRNA-synt_2b PF00587.20 EDN03871.1 - 4.5e-24 84.9 0.1 7.7e-24 84.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDN03871.1 - 2.5e-10 40.1 0.0 6.4e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain TraB PF01963.12 EDN03871.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 TraB family zinc_ribbon_5 PF13719.1 EDN03871.1 - 3.7 7.2 4.8 7.4 6.2 0.1 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EDN03871.1 - 4.9 6.9 5.2 7.9 6.2 0.1 2.9 2 0 0 2 2 2 0 zinc-ribbon domain CBF PF03914.12 EDN03872.1 - 6.6e-49 165.5 0.1 1.9e-48 163.9 0.0 1.9 1 0 0 1 1 1 1 CBF/Mak21 family Kelch_1 PF01344.20 EDN03872.1 - 0.23 11.0 0.0 0.53 9.8 0.0 1.6 1 0 0 1 1 1 0 Kelch motif LANC_like PF05147.8 EDN03873.1 - 6.1e-24 84.2 0.0 6.5e-15 54.5 0.0 3.2 1 1 1 2 2 2 2 Lanthionine synthetase C-like protein Ribosomal_L27 PF01016.14 EDN03873.1 - 0.029 14.1 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L27 protein Aa_trans PF01490.13 EDN03874.1 - 2.3e-18 65.8 20.2 2.3e-18 65.8 14.0 1.9 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein TPR_19 PF14559.1 EDN03874.1 - 0.00038 20.7 0.8 0.044 14.1 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN03874.1 - 0.0021 18.5 0.7 0.099 13.3 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_22 PF13401.1 EDN03874.1 - 0.023 14.8 0.0 0.069 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain LAM_C PF12544.3 EDN03874.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Lysine-2,3-aminomutase TPR_17 PF13431.1 EDN03874.1 - 0.14 12.4 0.2 1.1 9.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDN03874.1 - 0.16 12.4 0.7 55 4.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2534 PF10749.4 EDN03874.1 - 1.9 8.4 8.8 0.18 11.7 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) DnaG_DnaB_bind PF08278.6 EDN03875.1 - 0.042 14.0 0.2 0.096 12.9 0.1 1.6 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding DUF1495 PF07381.6 EDN03875.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) APS_kinase PF01583.15 EDN03877.1 - 9e-42 142.3 0.2 7.6e-27 93.8 0.1 2.1 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_33 PF13671.1 EDN03877.1 - 3.2e-05 23.8 0.0 4.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN03877.1 - 4e-05 24.4 0.0 4.6e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDN03877.1 - 7.3e-05 23.0 0.0 9.3e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EDN03877.1 - 0.0038 16.4 0.0 0.0051 16.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 EDN03877.1 - 0.051 13.0 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EDN03877.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EDN03877.1 - 0.12 12.2 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.13 EDN03877.1 - 0.14 11.2 0.0 0.35 9.9 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase V-ATPase_C PF03223.10 EDN03878.1 - 5e-111 371.2 0.0 5.6e-111 371.0 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C 4HBT PF03061.17 EDN03879.1 - 2.9e-12 46.5 0.0 5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Ligase_CoA PF00549.14 EDN03881.1 - 5.5e-19 68.2 0.0 6.4e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 CoA-ligase DUF3435 PF11917.3 EDN03883.1 - 2.4e-36 125.3 0.0 1.7e-35 122.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) DUF371 PF04027.8 EDN03883.1 - 0.11 12.1 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF371) Myb_DNA-binding PF00249.26 EDN03887.1 - 4.6e-10 39.3 0.0 9e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN03887.1 - 2.6e-06 27.4 0.1 5.8e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain BH4 PF02180.12 EDN03887.1 - 0.042 13.3 0.8 0.43 10.1 0.0 2.3 2 0 0 2 2 2 0 Bcl-2 homology region 4 BCS1_N PF08740.6 EDN03888.1 - 1e-34 119.7 0.0 1.8e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN03888.1 - 4.1e-19 69.0 0.0 1e-18 67.7 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDN03888.1 - 0.004 17.9 0.1 0.036 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDN03888.1 - 0.0067 16.4 0.1 0.049 13.6 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EDN03888.1 - 0.0075 15.6 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDN03888.1 - 0.038 13.8 0.1 0.43 10.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EDN03888.1 - 0.038 13.7 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN03888.1 - 0.045 13.8 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDN03888.1 - 0.059 13.6 0.0 20 5.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain PPV_E1_C PF00519.12 EDN03888.1 - 0.067 11.7 0.0 0.13 10.8 0.0 1.4 1 0 0 1 1 1 0 Papillomavirus helicase KaiC PF06745.8 EDN03888.1 - 0.09 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 EDN03888.1 - 0.099 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DDE_1 PF03184.14 EDN03891.1 - 4e-21 75.1 0.2 7.9e-21 74.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease PFL PF02901.10 EDN03891.1 - 0.0087 14.5 1.6 0.0087 14.5 1.1 1.4 1 1 0 1 1 1 1 Pyruvate formate lyase Pkinase PF00069.20 EDN03892.1 - 9.6e-30 103.5 0.0 1.4e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN03892.1 - 2.1e-11 43.4 0.0 1.5e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Chromo PF00385.19 EDN03893.1 - 2.8e-06 26.8 0.3 5.7e-06 25.9 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 EDN03894.1 - 2.1e-28 99.1 0.0 3.4e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN03894.1 - 1.9e-13 50.0 0.0 4e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN03894.1 - 7.8e-09 35.9 0.0 2.9e-08 34.1 0.0 2.0 1 1 0 1 1 1 1 RNase H Myb_DNA-bind_6 PF13921.1 EDN03896.1 - 0.00016 21.6 0.1 0.00039 20.4 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain CDC45 PF02724.9 EDN03896.1 - 9.2 4.1 6.8 13 3.6 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA PF00004.24 EDN03897.1 - 9.3e-19 67.9 0.0 2.5e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN03897.1 - 0.00021 21.3 0.2 0.0014 18.6 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain AAA_17 PF13207.1 EDN03897.1 - 0.00042 21.1 2.5 0.0017 19.1 0.1 3.0 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EDN03897.1 - 0.00055 20.2 0.5 0.094 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDN03897.1 - 0.00058 19.5 0.0 0.0016 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN03897.1 - 0.0021 18.2 0.1 0.042 13.9 0.0 2.7 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EDN03897.1 - 0.0088 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.6 EDN03897.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EDN03897.1 - 0.017 14.6 0.0 0.076 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EDN03897.1 - 0.019 13.9 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EDN03897.1 - 0.045 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDN03897.1 - 0.046 13.9 0.0 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 EDN03897.1 - 0.051 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain tRNA-synt_1d PF00750.14 EDN03898.1 - 0.048 12.4 1.3 0.058 12.2 0.9 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (R) APH PF01636.18 EDN03899.1 - 8.6e-05 22.3 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Tmpp129 PF10272.4 EDN03900.1 - 0.053 12.2 0.3 0.071 11.8 0.2 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor RasGEF PF00617.14 EDN03901.1 - 9e-07 28.8 0.1 5.3e-05 23.0 0.0 2.4 1 1 0 1 1 1 1 RasGEF domain F-box-like PF12937.2 EDN03902.1 - 0.00028 20.5 0.0 0.00073 19.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF4589 PF15252.1 EDN03904.1 - 3.1 7.5 14.5 0.075 12.8 4.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4589) Rad60-SLD PF11976.3 EDN03905.1 - 8.6e-21 73.4 0.5 1.1e-20 73.0 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EDN03905.1 - 9.3e-10 37.7 0.2 1.1e-09 37.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 EDN03905.1 - 0.028 14.1 0.1 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Nup84_Nup100 PF04121.8 EDN03906.1 - 1.5e-06 26.2 3.0 2.9e-06 25.2 2.1 1.4 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Daxx PF03344.10 EDN03906.1 - 0.0025 16.3 26.7 0.0036 15.8 18.5 1.2 1 0 0 1 1 1 1 Daxx Family Nup84_Nup100 PF04121.8 EDN03907.1 - 2.3e-29 101.6 0.0 1.6e-19 69.0 0.0 2.2 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 HD PF01966.17 EDN03908.1 - 0.00075 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 HD domain Anti-adapt_IraP PF10796.4 EDN03908.1 - 0.086 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein E1-E2_ATPase PF00122.15 EDN03909.1 - 7.6e-58 195.2 1.7 1.8e-57 194.0 1.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDN03909.1 - 3.7e-43 147.1 9.6 3.7e-43 147.1 6.7 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDN03909.1 - 7.5e-27 95.1 0.0 4.1e-26 92.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN03909.1 - 1.7e-20 72.7 0.0 3.2e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EDN03909.1 - 1.3e-12 48.2 0.0 3e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDN03909.1 - 7.8e-06 25.2 0.1 2.9e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Chromo PF00385.19 EDN03910.1 - 8.4e-05 22.1 0.1 0.00018 21.1 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.20 EDN03911.1 - 1.4e-09 37.4 0.0 2.6e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN03911.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 EDN03911.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3091 PF11291.3 EDN03912.1 - 0.065 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) DEAD PF00270.24 EDN03913.1 - 3e-11 43.1 0.0 6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN03913.1 - 5.4e-05 23.1 0.1 0.00076 19.3 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDN03913.1 - 0.11 12.6 0.1 0.39 10.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain DUF2236 PF09995.4 EDN03914.1 - 4.1e-10 39.3 0.3 1e-09 38.0 0.2 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Aldedh PF00171.17 EDN03915.1 - 2e-101 339.6 0.3 2.8e-101 339.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tubulin PF00091.20 EDN03916.1 - 1.2e-55 188.6 0.0 3.2e-55 187.2 0.0 1.7 1 1 1 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDN03916.1 - 2e-48 163.6 0.1 3.3e-48 162.8 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EDN03916.1 - 0.005 16.3 0.0 0.0091 15.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 EDN03917.1 - 3.1e-16 58.7 0.5 1.2e-07 31.2 0.1 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN03917.1 - 4.9e-12 45.6 0.2 1.7e-06 27.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN03917.1 - 2.1e-10 40.3 0.0 7.4e-07 28.9 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EDN03918.1 - 1.9e-64 217.3 0.0 3.4e-64 216.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN03918.1 - 2.2e-34 118.6 0.0 2.3e-33 115.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN03918.1 - 7.6e-08 31.6 0.1 1.1e-06 27.8 0.1 2.2 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EDN03918.1 - 0.00011 22.0 0.5 0.0022 17.7 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDN03918.1 - 0.012 14.4 0.1 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 EDN03918.1 - 0.094 12.0 0.2 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 RIO1 family EF1_GNE PF00736.14 EDN03919.1 - 4.8e-13 48.5 0.7 1.2e-09 37.6 0.5 2.4 2 0 0 2 2 2 2 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EDN03919.1 - 1.3e-10 41.1 1.0 1.3e-10 41.1 0.7 3.6 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EDN03919.1 - 0.025 15.0 0.0 0.07 13.6 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EDN03919.1 - 0.079 12.9 0.1 0.23 11.4 0.1 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AAA PF00004.24 EDN03920.1 - 1.5e-11 44.5 0.0 2.1e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN03920.1 - 3.6e-08 33.5 0.3 0.00015 21.7 0.1 2.2 1 1 1 2 2 2 2 AAA ATPase domain Arch_ATPase PF01637.13 EDN03920.1 - 2.3e-05 24.2 0.2 0.005 16.5 0.1 2.1 1 1 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EDN03920.1 - 7.7e-05 22.8 0.1 0.00014 22.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN03920.1 - 0.0012 18.5 0.1 0.0024 17.6 0.1 1.6 1 1 0 1 1 1 1 Part of AAA domain TrwB_AAD_bind PF10412.4 EDN03920.1 - 0.0047 15.6 0.1 0.017 13.7 0.0 1.7 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 EDN03920.1 - 0.0065 16.7 0.1 0.0098 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EDN03920.1 - 0.0071 15.7 0.0 0.008 15.6 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EDN03920.1 - 0.0096 15.8 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EDN03920.1 - 0.0097 14.8 0.1 0.061 12.2 0.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.7 EDN03920.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.4 1 1 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 EDN03920.1 - 0.014 14.8 0.1 0.12 11.7 0.1 1.9 1 1 1 2 2 2 0 AAA domain DUF853 PF05872.7 EDN03920.1 - 0.015 13.6 0.1 0.019 13.3 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_30 PF13604.1 EDN03920.1 - 0.017 14.6 0.1 0.031 13.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.16 EDN03920.1 - 0.018 14.3 0.3 0.031 13.5 0.1 1.4 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain Sigma54_activat PF00158.21 EDN03920.1 - 0.029 13.8 0.2 0.091 12.2 0.1 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 EDN03920.1 - 0.03 14.0 0.2 0.07 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EDN03920.1 - 0.033 14.0 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EDN03920.1 - 0.07 12.1 0.0 0.078 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain TniB PF05621.6 EDN03920.1 - 0.074 11.8 0.0 0.099 11.3 0.0 1.4 1 1 0 1 1 1 0 Bacterial TniB protein Miro PF08477.8 EDN03920.1 - 0.09 13.2 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein PhoH PF02562.11 EDN03920.1 - 0.091 11.9 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ClpB_D2-small PF10431.4 EDN03921.1 - 1.4e-26 92.1 0.0 2.4e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_2 PF07724.9 EDN03921.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) MutS_V PF00488.16 EDN03922.1 - 2.1e-24 86.2 0.0 8.5e-15 54.8 0.0 3.1 2 1 1 3 3 3 2 MutS domain V MutS_III PF05192.13 EDN03922.1 - 2.9e-13 50.0 0.0 3.9e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain III RdRP_3 PF00998.18 EDN03922.1 - 0.15 10.5 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase Sas10 PF09368.5 EDN03923.1 - 3.7e-30 103.8 9.0 3.7e-30 103.8 6.2 2.6 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EDN03923.1 - 1.4e-18 66.8 0.1 6.8e-18 64.6 0.0 2.2 2 0 0 2 2 2 1 Sas10/Utp3/C1D family adh_short PF00106.20 EDN03924.1 - 5.8e-20 71.8 0.0 7.8e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN03924.1 - 3.8e-09 36.4 0.1 8.2e-08 32.1 0.1 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EDN03924.1 - 1e-05 25.6 0.1 0.00014 21.8 0.0 2.4 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 EDN03924.1 - 5.6e-05 23.0 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EDN03924.1 - 9.4e-05 21.9 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EDN03924.1 - 0.00015 21.8 0.0 0.00039 20.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 EDN03924.1 - 0.001 18.1 0.2 0.0017 17.4 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.11 EDN03924.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EDN03924.1 - 0.053 13.7 0.0 0.096 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EDN03924.1 - 0.083 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EDN03924.1 - 0.088 12.6 0.1 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF1218 PF06749.7 EDN03926.1 - 0.22 12.0 3.4 7 7.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) PP1_inhibitor PF05361.7 EDN03927.1 - 0.019 14.6 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor Ribosomal_L6e PF01159.14 EDN03928.1 - 1.9e-38 130.9 0.6 1.9e-38 130.9 0.4 1.4 2 0 0 2 2 2 1 Ribosomal protein L6e Proteasom_Rpn13 PF04683.8 EDN03929.1 - 4.4e-27 93.9 0.0 6.3e-27 93.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ion_trans PF00520.26 EDN03930.1 - 3.7e-105 349.5 73.5 1.4e-33 115.8 4.6 5.1 5 0 0 5 5 5 4 Ion transport protein PKD_channel PF08016.7 EDN03930.1 - 0.00014 20.4 57.3 0.0058 15.1 1.1 6.3 6 0 0 6 6 6 5 Polycystin cation channel EF-hand_1 PF00036.27 EDN03930.1 - 0.0039 16.3 0.0 0.013 14.7 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EDN03930.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair JSRP PF15312.1 EDN03930.1 - 0.052 13.5 0.0 0.28 11.1 0.0 2.3 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein DAGK_cat PF00781.19 EDN03932.1 - 1.1e-23 83.0 0.1 2.6e-23 81.8 0.0 1.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.7 EDN03933.1 - 4.4e-43 147.2 0.2 3.5e-36 124.6 0.3 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 TAN PF11640.3 EDN03933.1 - 0.029 14.0 0.1 0.066 12.9 0.0 1.6 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair TP1 PF02079.11 EDN03933.1 - 1.5 8.6 8.0 4.1 7.2 5.6 1.7 1 0 0 1 1 1 0 Nuclear transition protein 1 RIO1 PF01163.17 EDN03934.1 - 0.17 11.2 0.0 7.9 5.7 0.0 2.2 2 0 0 2 2 2 0 RIO1 family DUF3435 PF11917.3 EDN03935.1 - 7.4e-118 393.8 0.6 8.7e-114 380.4 0.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) rve PF00665.21 EDN03936.1 - 4.6e-15 55.7 0.0 1.1e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.9 EDN03936.1 - 1.1e-06 27.7 0.0 1.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EDN03936.1 - 9e-05 22.2 2.2 0.00021 21.0 1.5 1.7 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.1 EDN03936.1 - 0.00018 21.0 0.1 0.0006 19.4 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-C4pol PF14260.1 EDN03936.1 - 0.42 10.6 3.2 0.92 9.5 1.3 2.1 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta RVT_1 PF00078.22 EDN03937.1 - 5.1e-28 97.9 0.0 8.2e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN03937.1 - 1.9e-14 54.1 0.0 3.9e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 RNase H Pkinase PF00069.20 EDN03938.1 - 4.1e-35 121.1 0.6 4.2e-22 78.5 0.1 3.1 1 1 1 2 2 2 2 Protein kinase domain KA1 PF02149.14 EDN03938.1 - 1.9e-17 62.4 0.2 3.4e-17 61.6 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Pkinase_Tyr PF07714.12 EDN03938.1 - 3.3e-15 55.8 0.1 6.6e-09 35.2 0.1 2.6 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDN03938.1 - 0.0071 15.3 0.0 0.038 12.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like DUF1604 PF07713.8 EDN03939.1 - 1.9e-38 130.1 4.0 4.4e-38 128.9 0.7 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EDN03939.1 - 3.9e-07 29.7 0.6 3.9e-07 29.7 0.4 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EDN03939.1 - 0.023 14.5 4.4 0.025 14.4 0.8 2.8 2 1 0 2 2 2 0 DExH-box splicing factor binding site NUDE_C PF04880.8 EDN03940.1 - 0.35 11.2 2.8 0.24 11.7 0.3 1.8 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region NAM-associated PF14303.1 EDN03940.1 - 0.53 10.5 5.1 1 9.6 3.6 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Pkinase PF00069.20 EDN03941.1 - 7e-21 74.5 0.0 2.7e-13 49.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN03941.1 - 2.3e-06 26.8 0.0 0.0025 16.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase CCDC92 PF14916.1 EDN03942.1 - 0.039 13.5 0.1 0.053 13.1 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain of unknown function RmuC PF02646.11 EDN03942.1 - 0.06 12.1 0.3 0.081 11.7 0.2 1.2 1 0 0 1 1 1 0 RmuC family ubiquitin PF00240.18 EDN03943.1 - 0.0024 17.2 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EDN03943.1 - 0.042 13.5 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDN03943.1 - 0.048 13.8 0.1 0.16 12.1 0.0 1.8 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain DUF837 PF05769.6 EDN03944.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF837) Exo_endo_phos_2 PF14529.1 EDN03945.1 - 8.6e-10 38.2 0.0 1.4e-05 24.6 0.0 2.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN03945.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EDN03946.1 - 4e-20 72.0 0.0 6.2e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Sigma_1s PF02454.11 EDN03947.1 - 0.094 12.4 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Sigma 1s protein SET PF00856.23 EDN03948.1 - 7.1e-22 78.4 0.1 1.8e-21 77.0 0.0 1.7 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EDN03948.1 - 3.3e-13 49.7 0.7 3.3e-13 49.7 0.5 2.5 3 0 0 3 3 3 2 Pre-SET motif Adaptin_N PF01602.15 EDN03949.1 - 2.3e-95 319.9 8.4 2.3e-95 319.9 5.8 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 EDN03949.1 - 4.4e-63 211.1 0.5 9.6e-63 210.0 0.4 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 EDN03949.1 - 1e-61 206.3 0.0 3.1e-61 204.8 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 EDN03949.1 - 2.5e-11 43.7 7.1 1.7e-06 28.2 0.0 4.8 2 2 3 5 5 5 3 HEAT repeats Cnd1 PF12717.2 EDN03949.1 - 1.1e-06 28.6 8.2 0.048 13.5 0.0 4.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EDN03949.1 - 0.00035 20.4 2.0 1.2 9.3 0.0 5.2 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EDN03949.1 - 0.0021 18.4 6.2 0.41 11.1 0.0 5.3 5 1 1 6 6 6 2 HEAT-like repeat AP4E_app_platf PF14807.1 EDN03949.1 - 0.018 15.2 0.1 0.09 13.0 0.1 2.3 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Arm PF00514.18 EDN03949.1 - 0.041 13.7 0.1 3.7 7.5 0.0 4.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Mago_nashi PF02792.9 EDN03950.1 - 1e-21 77.1 1.3 1.3e-21 76.7 0.9 1.1 1 0 0 1 1 1 1 Mago nashi protein Vac_ImportDeg PF09783.4 EDN03951.1 - 5.1e-44 149.8 3.2 7.9e-43 145.9 0.4 2.1 1 1 1 2 2 2 2 Vacuolar import and degradation protein DUF508 PF04370.7 EDN03951.1 - 0.26 10.8 3.1 0.45 10.1 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) PAN_2 PF08276.6 EDN03952.1 - 0.68 9.8 4.7 0.24 11.2 0.8 1.9 2 0 0 2 2 2 0 PAN-like domain MMgT PF10270.4 EDN03953.1 - 1.4e-29 102.5 0.0 1.7e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter FAD_binding_4 PF01565.18 EDN03954.1 - 3.1e-26 91.5 0.1 5.4e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain UQ_con PF00179.21 EDN03956.1 - 4.1e-07 29.4 0.0 9.8e-07 28.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RNB PF00773.14 EDN03957.1 - 1.1e-63 215.5 8.1 1.1e-43 149.7 0.0 3.2 3 1 1 4 4 4 2 RNB domain GLE1 PF07817.8 EDN03958.1 - 2.4e-13 49.6 0.9 7.7e-13 47.9 0.0 2.2 2 0 0 2 2 2 1 GLE1-like protein MIP-T3 PF10243.4 EDN03958.1 - 0.027 12.9 42.3 0.036 12.5 29.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 LMBR1 PF04791.11 EDN03958.1 - 0.13 10.8 4.5 0.11 11.0 2.5 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein SOBP PF15279.1 EDN03958.1 - 0.76 10.0 7.3 1.3 9.3 5.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Asp-B-Hydro_N PF05279.6 EDN03958.1 - 1.7 8.4 37.4 3.2 7.5 26.0 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF572 PF04502.8 EDN03958.1 - 2.1 7.5 34.6 2.9 7.0 24.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) PLRV_ORF5 PF01690.12 EDN03958.1 - 7.5 5.5 21.6 9.9 5.1 15.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DDE_3 PF13358.1 EDN03959.1 - 1.1e-06 28.4 2.2 3.1e-06 27.0 1.5 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease zf-3CxxC PF13695.1 EDN03960.1 - 1.9e-22 79.2 1.4 2e-22 79.2 0.0 1.7 2 1 0 2 2 2 1 Zinc-binding domain DUF711 PF05167.7 EDN03960.1 - 0.088 11.5 0.0 0.099 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) RVT_1 PF00078.22 EDN03961.1 - 3.4e-28 98.4 0.0 5.5e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN03961.1 - 7.2e-15 55.4 0.0 1.5e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 RNase H Glyco_hydro_17 PF00332.13 EDN03963.1 - 1.9e-31 109.2 0.3 1.9e-29 102.6 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Myb_DNA-bind_6 PF13921.1 EDN03964.1 - 0.0001 22.3 0.6 0.011 15.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN03964.1 - 0.0005 20.0 0.7 0.13 12.3 0.2 2.5 2 1 0 2 2 2 2 Myb-like DNA-binding domain PAT1 PF09770.4 EDN03964.1 - 2 6.5 17.3 2.7 6.0 12.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EMP24_GP25L PF01105.19 EDN03966.1 - 2.1e-06 27.6 0.0 2.4e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD KR PF08659.5 EDN03968.1 - 6.1e-24 84.6 0.9 3.8e-12 46.2 0.0 2.3 1 1 1 2 2 2 2 KR domain adh_short PF00106.20 EDN03968.1 - 5.1e-19 68.8 1.1 2e-10 40.8 0.0 2.5 1 1 1 2 2 2 2 short chain dehydrogenase Fungal_trans PF04082.13 EDN03968.1 - 1.7e-15 56.6 0.2 3.1e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.21 EDN03968.1 - 2.8e-12 46.6 0.0 5.4e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ADH_zinc_N PF00107.21 EDN03968.1 - 1.3e-06 27.9 0.0 3.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN03968.1 - 0.0072 16.0 0.0 0.021 14.5 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain F420_oxidored PF03807.12 EDN03968.1 - 0.02 15.2 0.1 0.061 13.7 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EDN03968.1 - 0.021 13.7 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EDN03968.1 - 0.053 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EDN03968.1 - 0.1 12.0 0.1 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family HpcH_HpaI PF03328.9 EDN03969.1 - 7.7e-10 38.0 0.1 8.9e-05 21.4 0.0 2.1 2 0 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family CS PF04969.11 EDN03970.1 - 7.1e-08 32.8 0.1 9e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 CS domain GCR1_C PF12550.3 EDN03972.1 - 4.7e-15 55.2 0.1 2.1e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes DRY_EERY PF09750.4 EDN03972.1 - 0.23 11.5 3.3 0.47 10.5 1.7 1.8 1 1 0 1 1 1 0 Alternative splicing regulator Fungal_trans PF04082.13 EDN03973.1 - 1.1e-24 86.6 0.0 1.4e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3716 PF12511.3 EDN03974.1 - 5.4e-16 57.9 2.5 7.1e-16 57.5 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Methyltransf_3 PF01596.12 EDN03975.1 - 1.1e-28 99.7 0.0 1.6e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EDN03975.1 - 2.1e-15 57.4 0.0 3.3e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN03975.1 - 8e-11 42.5 0.0 1.1e-10 42.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN03975.1 - 1.7e-09 37.4 0.0 2.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN03975.1 - 6e-05 23.0 0.0 0.00016 21.6 0.0 1.5 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN03975.1 - 9.1e-05 22.7 0.0 0.00013 22.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN03975.1 - 0.00045 20.6 0.0 0.00088 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDN03975.1 - 0.0024 17.4 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 EDN03975.1 - 0.0047 16.3 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.7 EDN03975.1 - 0.0052 17.2 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF3224 PF11528.3 EDN03975.1 - 0.031 13.7 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) CMAS PF02353.15 EDN03975.1 - 0.069 12.2 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase CmcI PF04989.7 EDN03975.1 - 0.09 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_23 PF13489.1 EDN03975.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 EDN03976.1 - 1.5e-71 241.3 0.0 1.8e-71 241.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.7 EDN03977.1 - 1.1e-06 28.3 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CtnDOT_TraJ PF07863.6 EDN03977.1 - 0.072 13.5 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon AMP-binding PF00501.23 EDN03978.1 - 2.4e-173 576.3 0.0 5.7e-90 301.6 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EDN03978.1 - 3.7e-54 183.6 0.0 5.4e-21 74.7 0.0 4.4 3 1 1 4 4 4 4 Condensation domain AMP-binding_C PF13193.1 EDN03978.1 - 1.1e-10 42.2 0.0 0.001 19.9 0.0 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EDN03978.1 - 6.7e-08 32.6 0.0 2.3e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF3405 PF11885.3 EDN03979.1 - 1.1e-220 733.1 0.0 1.2e-220 732.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DUF4046 PF13255.1 EDN03980.1 - 0.012 14.3 0.1 0.018 13.7 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4046) Arf PF00025.16 EDN03982.1 - 3.4e-66 221.7 0.2 4.9e-66 221.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDN03982.1 - 1.2e-12 47.4 0.0 1.5e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EDN03982.1 - 5.3e-11 42.1 0.0 6.9e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EDN03982.1 - 5.4e-11 41.7 1.4 1.2e-08 34.1 0.2 2.1 1 1 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDN03982.1 - 1.6e-09 37.2 0.0 2e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDN03982.1 - 4e-07 30.5 0.0 5.2e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDN03982.1 - 6.2e-05 22.9 0.0 8.7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EDN03982.1 - 0.1 11.6 0.1 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase rve PF00665.21 EDN03983.1 - 4.2e-16 59.1 0.0 8.7e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN03983.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain DUF4219 PF13961.1 EDN03983.1 - 0.025 14.0 0.2 0.025 14.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) zf-CCHC PF00098.18 EDN03983.1 - 2.5 8.1 4.3 4.7 7.3 3.0 1.5 1 0 0 1 1 1 0 Zinc knuckle CorA PF01544.13 EDN03984.1 - 0.00034 19.7 0.6 0.00034 19.7 0.4 2.3 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Herpes_V23 PF01802.12 EDN03984.1 - 0.058 12.4 0.2 0.091 11.7 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein SieB PF14163.1 EDN03984.1 - 1.2 8.6 6.0 0.32 10.5 1.6 1.9 2 0 0 2 2 2 0 Superinfection exclusion protein B Ribosomal_L1 PF00687.16 EDN03985.1 - 3e-53 180.4 0.7 3.6e-53 180.1 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DEK_C PF08766.6 EDN03985.1 - 0.3 10.9 0.1 0.3 10.9 0.0 2.6 3 0 0 3 3 3 0 DEK C terminal domain GLYCAM-1 PF05242.6 EDN03986.1 - 0.12 12.2 1.2 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) WH2 PF02205.15 EDN03987.1 - 2.8e-09 36.2 0.6 2.8e-09 36.2 0.4 2.1 2 0 0 2 2 2 1 WH2 motif zf-B_box PF00643.19 EDN03988.1 - 0.32 10.9 12.6 0.081 12.8 1.0 3.4 3 0 0 3 3 3 0 B-box zinc finger LSM PF01423.17 EDN03989.1 - 1.4e-14 53.4 0.1 2e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain Peptidase_U32 PF01136.14 EDN03989.1 - 0.035 13.0 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase family U32 DUF3377 PF11857.3 EDN03991.1 - 1 9.0 6.2 2.1 8.0 3.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) SURF4 PF02077.10 EDN03992.1 - 1.2e-94 316.6 6.8 1.3e-94 316.5 4.7 1.0 1 0 0 1 1 1 1 SURF4 family UPF0139 PF03669.8 EDN03992.1 - 0.031 13.7 1.2 0.085 12.3 0.8 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0139) DUF1430 PF07242.6 EDN03992.1 - 0.66 10.0 7.8 3.3 7.8 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) eIF_4EBP PF05456.6 EDN03993.1 - 0.32 10.6 5.9 0.38 10.4 0.4 2.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) IU_nuc_hydro PF01156.14 EDN03994.1 - 2.2e-53 181.5 0.0 6.4e-52 176.7 0.0 2.1 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase p450 PF00067.17 EDN03996.1 - 8.5e-27 93.7 0.0 1e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EDN03997.1 - 7.5e-19 67.6 0.2 1.2e-18 66.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN03997.1 - 2.6e-07 30.4 9.2 4.8e-07 29.5 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EDN03998.1 - 1.9e-16 59.7 23.6 4.2e-16 58.6 13.4 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily Cu_amine_oxid PF01179.15 EDN03999.1 - 3.6e-161 536.5 0.0 4.3e-161 536.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EDN03999.1 - 4.7e-07 29.7 0.0 9.6e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EDN03999.1 - 2e-05 24.5 0.0 3.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DCR PF14047.1 EDN03999.1 - 0.072 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Dppa2/4 conserved region Rad51 PF08423.6 EDN04000.1 - 5.4e-23 81.1 0.0 8.6e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EDN04000.1 - 2.8e-12 46.4 0.0 5.9e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EDN04000.1 - 3.9e-06 26.1 0.2 5.3e-05 22.4 0.2 2.3 1 1 0 1 1 1 1 KaiC RecA PF00154.16 EDN04000.1 - 0.0017 17.4 0.1 0.15 11.1 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_22 PF13401.1 EDN04000.1 - 0.11 12.6 0.0 0.41 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain FA_desaturase PF00487.19 EDN04001.1 - 9.3e-25 87.5 21.0 1.3e-24 87.0 14.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EDN04001.1 - 1e-07 32.0 0.0 1.8e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) TRAPPC10 PF12584.3 EDN04002.1 - 4.2e-36 123.6 0.0 7.2e-36 122.8 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Ank_2 PF12796.2 EDN04002.1 - 2.3e-12 47.0 0.1 5.1e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EDN04002.1 - 1.2e-11 43.7 5.9 2.6e-05 23.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 EDN04002.1 - 1.9e-10 40.5 0.3 1.9e-10 40.5 0.2 3.5 4 0 0 4 4 4 1 IPT/TIG domain Ank_4 PF13637.1 EDN04002.1 - 2.7e-10 40.4 0.6 8.7e-10 38.8 0.4 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN04002.1 - 2.5e-09 36.4 1.6 0.0025 17.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EDN04002.1 - 1.1e-07 31.8 2.0 4.9e-05 23.4 1.4 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Foie-gras_1 PF11817.3 EDN04002.1 - 0.0092 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 Bap31 PF05529.7 EDN04002.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Pro_isomerase PF00160.16 EDN04005.1 - 3.1e-46 157.4 0.6 3.4e-46 157.2 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_2c PF01411.14 EDN04006.1 - 8.5e-208 691.1 0.0 1.2e-207 690.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EDN04006.1 - 5.6e-18 64.5 0.6 1.4e-17 63.2 0.4 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EDN04006.1 - 1.9e-07 30.7 0.7 5.4e-07 29.2 0.5 1.9 1 0 0 1 1 1 1 DHHA1 domain DUF3752 PF12572.3 EDN04008.1 - 6e-45 153.0 9.4 6e-45 153.0 6.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) A_deaminase PF00962.17 EDN04013.1 - 3.6e-110 367.9 0.0 4.9e-110 367.5 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase F-box-like PF12937.2 EDN04014.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EDN04014.1 - 0.19 11.4 0.0 0.55 9.9 0.0 1.7 1 0 0 1 1 1 0 F-box domain DUF4192 PF13830.1 EDN04014.1 - 3.7 7.1 6.5 7.4 6.1 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) SH3_9 PF14604.1 EDN04015.1 - 3.2e-16 58.6 0.8 1.1e-11 44.1 0.3 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EDN04015.1 - 7.5e-15 54.0 1.6 6.2e-09 35.1 0.3 2.5 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.15 EDN04015.1 - 9.2e-10 38.4 0.0 2.1e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.12 EDN04015.1 - 6.4e-07 28.7 1.0 1.4e-06 27.6 0.0 2.1 3 0 0 3 3 3 1 Variant SH3 domain PBP PF01161.15 EDN04016.1 - 8.2e-27 93.8 0.4 1.1e-26 93.4 0.3 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PLRV_ORF5 PF01690.12 EDN04016.1 - 0.16 11.0 11.8 0.24 10.5 8.2 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Dynamin_M PF01031.15 EDN04017.1 - 4.2e-114 380.2 0.0 6.8e-114 379.6 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 EDN04017.1 - 1.2e-31 108.4 0.4 3.7e-31 106.8 0.3 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain Dynamin_N PF00350.18 EDN04017.1 - 6.9e-14 52.0 0.9 5.9e-13 48.9 0.0 2.6 3 0 0 3 3 3 1 Dynamin family zf-CCHC_4 PF14392.1 EDN04017.1 - 0.1 12.2 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle GMC_oxred_N PF00732.14 EDN04018.1 - 3.9e-66 223.2 0.0 5e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN04018.1 - 1.7e-33 115.9 0.0 4e-33 114.7 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EDN04018.1 - 2.6e-09 36.4 1.2 9.1e-05 21.5 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDN04018.1 - 1.8e-06 27.0 1.1 0.00083 18.3 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EDN04018.1 - 1.9e-05 24.5 0.2 5.2e-05 23.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EDN04018.1 - 0.00015 20.8 0.1 0.00023 20.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EDN04018.1 - 0.00021 19.9 0.3 0.014 13.9 0.1 2.9 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.9 EDN04018.1 - 0.0016 18.3 0.1 0.0054 16.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDN04018.1 - 0.01 14.8 0.1 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EDN04018.1 - 0.036 14.4 0.1 0.25 11.7 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN04018.1 - 0.04 12.9 0.1 0.099 11.7 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EDN04018.1 - 0.046 13.7 0.1 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UAA PF08449.6 EDN04019.1 - 5.6e-34 117.4 3.2 7e-34 117.1 2.2 1.1 1 0 0 1 1 1 1 UAA transporter family Rad17 PF03215.10 EDN04020.1 - 1.5e-42 145.9 0.0 3.2e-41 141.6 0.0 2.2 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein ELMO_CED12 PF04727.8 EDN04021.1 - 1.5e-50 171.0 0.1 3.8e-50 169.7 0.1 1.7 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3361 PF11841.3 EDN04021.1 - 1.2e-05 25.0 0.2 0.00017 21.3 0.2 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) APH PF01636.18 EDN04023.1 - 0.00022 21.0 0.1 0.0005 19.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family SUI1 PF01253.17 EDN04024.1 - 2.2e-23 81.8 1.8 2.7e-23 81.5 0.4 1.8 1 1 1 2 2 2 1 Translation initiation factor SUI1 Peptidase_S64 PF08192.6 EDN04025.1 - 0.12 10.6 13.3 0.19 10.0 9.2 1.2 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.4 EDN04025.1 - 2.8 6.0 28.5 3.9 5.6 19.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cgr1 PF03879.9 EDN04026.1 - 4.8e-40 136.1 29.1 5.6e-40 135.8 20.2 1.0 1 0 0 1 1 1 1 Cgr1 family DUF572 PF04502.8 EDN04026.1 - 0.042 13.0 13.2 0.043 13.0 9.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PRP1_N PF06424.7 EDN04026.1 - 0.3 11.3 9.2 0.4 11.0 6.4 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal SprA-related PF12118.3 EDN04026.1 - 1.6 8.0 10.1 1.8 7.8 7.0 1.0 1 0 0 1 1 1 0 SprA-related family Ndufs5 PF10200.4 EDN04026.1 - 1.9 8.5 11.0 0.21 11.5 3.8 1.9 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CCDC74_C PF14917.1 EDN04026.1 - 2.6 8.1 10.4 0.021 14.8 1.7 1.6 2 0 0 2 2 2 0 Coiled coil protein 74, C terminal Mito_carr PF00153.22 EDN04027.1 - 5.2e-64 212.0 0.2 8e-22 76.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.17 EDN04028.1 - 1.3e-15 56.9 1.1 1.5e-15 56.6 0.8 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EDN04028.1 - 4.5e-10 39.5 1.6 9.8e-09 35.2 0.2 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EDN04028.1 - 0.034 13.5 4.2 0.18 11.1 0.1 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Kdo PF06293.9 EDN04030.1 - 0.0021 17.1 1.6 0.0021 17.1 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN04030.1 - 0.004 16.9 0.1 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN04030.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EDN04030.1 - 0.049 12.9 0.0 0.073 12.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 EDN04030.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain OmpH PF03938.9 EDN04031.1 - 0.03 14.2 0.2 0.064 13.2 0.1 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2381 PF09544.5 EDN04031.1 - 0.13 11.3 4.9 0.19 10.8 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) DUF4192 PF13830.1 EDN04031.1 - 0.27 10.8 6.5 0.4 10.2 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) LppC PF04348.8 EDN04033.1 - 0.091 11.2 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 LppC putative lipoprotein BNR PF02012.15 EDN04034.1 - 6.7e-11 40.3 30.5 0.93 9.5 0.1 11.9 12 0 0 12 12 12 7 BNR/Asp-box repeat Mo-co_dimer PF03404.11 EDN04034.1 - 0.0025 17.4 1.5 4 7.0 0.0 4.7 5 0 0 5 5 5 2 Mo-co oxidoreductase dimerisation domain Adeno_E3_CR2 PF02439.10 EDN04034.1 - 1.8 8.1 4.6 4.7 6.8 3.2 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TFIIS_M PF07500.9 EDN04036.1 - 3.8e-28 97.8 1.7 4.6e-28 97.5 0.5 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain Med26 PF08711.6 EDN04036.1 - 4.5e-15 54.8 0.4 9.7e-15 53.8 0.3 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain TFIIS_C PF01096.13 EDN04036.1 - 2.1e-14 52.8 3.2 4.8e-14 51.6 2.2 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) MPP6 PF10175.4 EDN04036.1 - 0.041 14.2 0.6 0.084 13.2 0.4 1.5 1 0 0 1 1 1 0 M-phase phosphoprotein 6 DUF3800 PF12686.2 EDN04036.1 - 0.047 13.3 0.1 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) Chordopox_A33R PF05966.7 EDN04036.1 - 0.052 12.3 0.5 0.19 10.5 0.0 2.0 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Cathelicidins PF00666.12 EDN04037.1 - 0.047 13.8 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Cathelicidin Fungal_trans PF04082.13 EDN04038.1 - 9.9e-19 67.2 0.1 1.2e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN04038.1 - 6.6e-08 32.3 13.6 1.3e-07 31.3 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec10 PF07393.6 EDN04040.1 - 9.8e-234 777.7 0.0 1.2e-233 777.4 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 LRR_6 PF13516.1 EDN04041.1 - 1.7e-08 33.6 0.1 8.1 6.8 0.0 6.0 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 EDN04041.1 - 7e-07 28.7 0.8 0.85 9.3 0.0 5.5 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EDN04041.1 - 0.0042 16.9 0.3 64 4.1 0.2 5.4 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 EDN04041.1 - 0.025 14.6 0.1 43 4.9 0.0 4.8 5 0 0 5 5 5 0 Leucine rich repeat Herpes_pp38 PF04846.8 EDN04042.1 - 0.013 14.7 0.2 0.027 13.7 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein RRM_1 PF00076.17 EDN04043.1 - 2.3e-40 136.0 0.0 5.3e-19 67.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN04043.1 - 1.9e-34 117.4 0.0 1.2e-16 60.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN04043.1 - 2.9e-20 71.8 0.0 2.3e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OapA PF04225.7 EDN04043.1 - 0.12 12.2 0.6 0.22 11.4 0.4 1.4 1 0 0 1 1 1 0 Opacity-associated protein A LysM-like domain Alg6_Alg8 PF03155.10 EDN04044.1 - 2.4e-128 428.9 27.2 7.5e-84 282.2 8.6 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family HNH_2 PF13391.1 EDN04047.1 - 3.2e-05 23.6 0.2 0.00013 21.6 0.1 2.1 1 1 0 1 1 1 1 HNH endonuclease Pkinase PF00069.20 EDN04048.1 - 7.9e-24 84.2 0.0 1.5e-11 43.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN04048.1 - 1.7e-09 37.1 2.0 0.00085 18.4 0.0 3.6 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EDN04048.1 - 0.12 11.2 0.0 4.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pex19 PF04614.7 EDN04050.1 - 2.5e-67 227.1 0.2 5.5e-67 225.9 0.1 1.7 1 1 0 1 1 1 1 Pex19 protein family Stm1_N PF09598.5 EDN04052.1 - 2.7e-17 63.2 3.0 2.7e-17 63.2 2.1 4.3 2 1 2 4 4 4 1 Stm1 GBA2_N PF12215.3 EDN04053.1 - 0.04 13.0 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal tRNA-synt_1c PF00749.16 EDN04054.1 - 3.4e-88 295.3 0.0 6.6e-88 294.3 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EDN04054.1 - 1.8e-31 109.1 0.0 3e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EDN04054.1 - 1.4e-07 31.9 0.0 4.6e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDN04054.1 - 0.093 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Helicase_C PF00271.26 EDN04057.1 - 2.5e-28 97.7 0.1 1.1e-27 95.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN04057.1 - 4.7e-18 65.2 0.0 1.2e-17 63.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EDN04057.1 - 0.054 12.2 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain HCO3_cotransp PF00955.16 EDN04058.1 - 4.1e-61 207.1 11.7 7.5e-41 140.3 3.5 3.1 1 1 2 3 3 3 3 HCO3- transporter family BCHF PF07284.6 EDN04058.1 - 0.016 15.0 0.4 0.052 13.4 0.2 1.9 1 1 0 1 1 1 0 2-vinyl bacteriochlorophyllide hydratase (BCHF) KH_1 PF00013.24 EDN04059.1 - 8.7e-09 34.8 0.2 1.6e-08 34.0 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EDN04059.1 - 1.4e-05 24.6 0.2 3.3e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.18 EDN04059.1 - 0.081 12.8 0.3 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle NAD_binding_6 PF08030.7 EDN04060.1 - 3.1e-17 62.9 0.0 1.8e-14 53.8 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EDN04060.1 - 6.3e-16 58.1 0.0 4.2e-15 55.5 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EDN04060.1 - 1.4e-07 31.6 11.9 2.2e-05 24.5 3.4 3.2 2 1 1 3 3 3 2 Ferric reductase like transmembrane component DUF1206 PF06724.6 EDN04060.1 - 0.87 9.3 0.0 0.87 9.3 0.0 3.6 5 0 0 5 5 5 0 Domain of Unknown Function (DUF1206) BCS1_N PF08740.6 EDN04061.1 - 1e-28 100.2 0.5 3.3e-25 88.7 0.0 2.4 1 1 1 2 2 2 2 BCS1 N terminal AAA PF00004.24 EDN04061.1 - 3.6e-11 43.3 0.4 1.4e-10 41.4 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF3619 PF12279.3 EDN04062.1 - 0.0061 16.6 0.2 0.0077 16.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3619) RNA_pol_Rpb4 PF03874.11 EDN04062.1 - 0.14 12.1 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb4 Pkinase PF00069.20 EDN04064.1 - 2.4e-13 49.8 0.0 2.9e-12 46.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN04064.1 - 3e-07 29.7 0.0 4.8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN04064.1 - 0.11 12.2 0.0 0.81 9.3 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family UQ_con PF00179.21 EDN04065.1 - 6.2e-40 135.8 0.0 7e-40 135.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDN04065.1 - 4.9e-07 29.5 0.0 6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDN04065.1 - 0.03 14.2 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 EDN04065.1 - 0.078 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain Peptidase_S24 PF00717.18 EDN04066.1 - 1.1e-07 31.3 0.2 2e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like BTB PF00651.26 EDN04069.1 - 6.2e-05 22.9 0.0 0.00025 21.0 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain RVT_1 PF00078.22 EDN04071.1 - 1.4e-25 89.8 0.0 3e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN04071.1 - 3.2e-20 72.4 0.1 1.5e-19 70.2 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EDN04071.1 - 9.9e-14 50.7 2.5 1.4e-13 50.2 0.7 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Retrotrans_gag PF03732.12 EDN04071.1 - 0.00013 21.9 2.0 0.00013 21.9 1.4 2.9 2 0 0 2 2 2 1 Retrotransposon gag protein zf-H2C2 PF09337.5 EDN04071.1 - 0.034 13.5 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger Mtf2_C PF14061.1 EDN04071.1 - 0.085 12.7 0.8 0.26 11.2 0.2 2.0 1 1 1 2 2 2 0 Polycomb-like MTF2 factor 2 Aminotran_1_2 PF00155.16 EDN04072.1 - 1.6e-82 277.3 0.0 2.2e-82 276.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EDN04072.1 - 1.7e-06 27.0 0.0 2.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EDN04072.1 - 4.7e-06 25.1 0.0 8.2e-06 24.3 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EDN04072.1 - 5.9e-05 22.2 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EDN04072.1 - 0.00011 21.4 0.0 0.00045 19.4 0.0 1.9 2 0 0 2 2 2 1 Beta-eliminating lyase RNA_pol_I_A49 PF06870.7 EDN04073.1 - 6.4e-46 156.6 0.0 9.7e-28 96.8 0.0 2.1 1 1 0 2 2 2 2 A49-like RNA polymerase I associated factor GATase PF00117.23 EDN04074.1 - 3.9e-46 156.9 0.0 5.3e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EDN04074.1 - 1.4e-44 150.7 0.0 2.4e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 EDN04074.1 - 8.6e-05 22.0 0.2 0.0012 18.2 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 DUF1250 PF06855.7 EDN04074.1 - 0.076 12.5 0.0 9.7 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) Peptidase_S10 PF00450.17 EDN04075.1 - 5.2e-48 164.2 0.0 1.1e-47 163.0 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.17 EDN04076.1 - 3.5e-10 39.6 0.0 5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase RNA_helicase PF00910.17 EDN04077.1 - 0.042 14.0 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ZZ PF00569.12 EDN04077.1 - 0.36 10.4 12.9 0.38 10.3 7.3 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type NIF PF03031.13 EDN04078.1 - 1e-48 165.0 0.0 1.2e-48 164.8 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Flexi_CP PF00286.15 EDN04078.1 - 0.15 11.7 0.1 1.1 8.9 0.1 2.1 2 0 0 2 2 2 0 Viral coat protein DUF963 PF06131.6 EDN04078.1 - 0.18 11.0 3.3 0.3 10.4 2.3 1.3 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) p450 PF00067.17 EDN04079.1 - 1.2e-47 162.5 0.0 1.5e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 His_Phos_2 PF00328.17 EDN04079.1 - 0.03 13.6 0.0 0.042 13.1 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) DIT1_PvcA PF05141.7 EDN04080.1 - 2.2e-85 286.3 0.0 3e-85 285.8 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein IF-2B PF01008.12 EDN04081.1 - 8.8e-53 179.1 0.2 1.7e-37 128.9 0.0 2.0 2 0 0 2 2 2 2 Initiation factor 2 subunit family 3HCDH_N PF02737.13 EDN04081.1 - 0.09 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ribosom_S12_S23 PF00164.20 EDN04082.1 - 7.9e-41 138.3 0.4 9.1e-41 138.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L17 PF01196.14 EDN04084.1 - 2.1e-30 105.1 0.0 3.7e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 Mn_catalase PF05067.7 EDN04084.1 - 0.11 11.2 0.1 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Manganese containing catalase SUZ PF12752.2 EDN04085.1 - 9.3e-22 77.3 3.1 9.3e-22 77.3 2.1 3.4 3 1 0 3 3 3 1 SUZ domain R3H PF01424.17 EDN04085.1 - 3.8e-06 26.5 0.0 8.6e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-CCHC_3 PF13917.1 EDN04086.1 - 6.1e-07 29.0 0.4 1.2e-06 28.1 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle cwf18 PF08315.7 EDN04087.1 - 1.1e-42 145.5 3.9 1.1e-42 145.5 2.7 1.9 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor PPR_3 PF13812.1 EDN04088.1 - 3.6e-10 39.2 1.1 0.072 13.3 0.0 6.6 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EDN04088.1 - 4.7e-09 36.0 0.0 0.00039 20.3 0.0 4.2 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.15 EDN04088.1 - 0.004 17.0 0.0 1.6 8.8 0.0 4.6 6 0 0 6 6 6 1 PPR repeat PPR_1 PF12854.2 EDN04088.1 - 0.015 14.7 0.0 10 5.7 0.0 3.3 3 0 0 3 3 3 0 PPR repeat MRP-S27 PF10037.4 EDN04088.1 - 0.041 12.8 0.0 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 DUF1242 PF06842.7 EDN04089.1 - 1.5e-14 53.1 0.1 2.3e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) TFIID-18kDa PF02269.11 EDN04090.1 - 3.1e-14 52.5 0.0 5.4e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 EDN04090.1 - 0.00028 20.9 0.0 0.00047 20.2 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EDN04090.1 - 0.0095 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID_20kDa PF03847.8 EDN04090.1 - 0.069 13.4 0.1 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A JAB PF01398.16 EDN04091.1 - 2.3e-17 62.7 0.0 3.8e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EDN04091.1 - 1.7e-16 60.3 0.1 3.1e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.8 EDN04091.1 - 0.032 13.7 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF1253 PF06862.7 EDN04092.1 - 5.9e-167 555.5 0.0 7.6e-167 555.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 EDN04092.1 - 0.017 14.5 0.0 0.8 9.1 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF2895 PF11444.3 EDN04092.1 - 0.1 11.8 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) EamA PF00892.15 EDN04093.1 - 2.8e-12 46.7 27.0 5.9e-08 32.8 3.7 3.5 3 1 0 3 3 3 3 EamA-like transporter family CTP_transf_2 PF01467.21 EDN04094.1 - 4.8e-15 55.9 0.0 9.5e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase PP2C PF00481.16 EDN04095.1 - 9e-26 90.7 4.8 2.1e-14 53.5 0.2 2.8 2 1 1 3 3 3 2 Protein phosphatase 2C Nop14 PF04147.7 EDN04095.1 - 0.0049 14.8 10.1 0.0064 14.4 7.0 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 EDN04095.1 - 0.018 13.1 10.3 0.023 12.7 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EDN04095.1 - 0.037 13.5 5.7 0.075 12.5 3.9 1.5 1 0 0 1 1 1 0 Nucleoplasmin SDA1 PF05285.7 EDN04095.1 - 0.24 10.6 9.4 0.34 10.1 6.5 1.1 1 0 0 1 1 1 0 SDA1 Menin PF05053.8 EDN04095.1 - 0.42 8.7 4.2 0.49 8.4 2.9 1.1 1 0 0 1 1 1 0 Menin IR1-M PF12185.3 EDN04095.1 - 0.97 9.2 6.6 2.5 7.8 4.6 1.7 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain CENP-B_dimeris PF09026.5 EDN04095.1 - 1.4 9.1 11.0 2.6 8.3 7.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain eIF-3c_N PF05470.7 EDN04095.1 - 1.7 6.6 6.1 2.2 6.2 4.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sporozoite_P67 PF05642.6 EDN04095.1 - 1.8 6.3 10.5 2.4 5.8 7.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 EDN04095.1 - 4.9 5.5 15.9 6.5 5.1 11.1 1.1 1 0 0 1 1 1 0 Daxx Family Ebola_NP PF05505.7 EDN04095.1 - 7.4 4.4 10.9 10 4.0 7.6 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Acetyltransf_1 PF00583.19 EDN04096.1 - 9e-09 35.2 0.3 1.7e-08 34.3 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EDN04096.1 - 8.8e-07 29.0 0.1 1.2e-06 28.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EDN04096.1 - 2.6e-05 24.2 0.5 7.4e-05 22.8 0.1 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EDN04096.1 - 0.002 17.9 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EDN04096.1 - 0.01 15.5 0.1 0.02 14.6 0.1 1.5 1 1 0 1 1 1 0 FR47-like protein DUF3749 PF12568.3 EDN04096.1 - 0.046 13.3 0.5 0.074 12.6 0.3 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZART1 PF12554.3 EDN04097.1 - 4e-25 86.9 1.3 5.4e-25 86.6 0.9 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DUF2489 PF10675.4 EDN04097.1 - 0.077 12.6 0.3 2.3 7.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) OB_NTP_bind PF07717.11 EDN04099.1 - 2.6e-22 78.7 0.0 4.5e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EDN04099.1 - 1.2e-17 63.7 0.0 2.7e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDN04099.1 - 3.5e-13 49.2 0.0 7.6e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EDN04099.1 - 4.5e-05 23.6 0.0 0.00013 22.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EDN04099.1 - 0.0013 18.2 0.1 0.0035 16.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EDN04099.1 - 0.0058 15.5 0.1 0.016 14.1 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein cobW PF02492.14 EDN04099.1 - 0.0082 15.5 0.1 0.2 11.0 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EDN04099.1 - 0.015 14.9 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EDN04099.1 - 0.037 13.9 0.1 2.7 7.9 0.1 2.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EDN04099.1 - 0.041 12.9 0.7 0.17 10.9 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.4 EDN04099.1 - 0.072 11.7 0.0 0.14 10.7 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 EDN04099.1 - 0.14 12.0 0.2 1.5 8.6 0.1 2.3 2 1 0 2 2 2 0 AAA domain PITH PF06201.8 EDN04100.1 - 3.6e-46 156.6 0.0 4.4e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 PITH domain Snf7 PF03357.16 EDN04101.1 - 4.6e-31 107.5 7.1 4.6e-31 107.5 4.9 1.8 2 0 0 2 2 2 1 Snf7 Silic_transp PF03842.8 EDN04101.1 - 0.11 10.4 0.4 0.16 9.9 0.3 1.2 1 0 0 1 1 1 0 Silicon transporter TCP PF03634.8 EDN04101.1 - 0.91 9.8 6.5 0.3 11.4 1.0 2.1 2 0 0 2 2 2 0 TCP family transcription factor DUF4559 PF15112.1 EDN04101.1 - 5.3 6.1 7.1 1.3 8.1 2.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) DUF2203 PF09969.4 EDN04101.1 - 6.7 6.9 8.0 17 5.6 1.0 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) AAA PF00004.24 EDN04102.1 - 6e-86 285.3 0.0 3.9e-44 150.0 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN04102.1 - 1.3e-13 51.2 0.5 0.0032 17.6 0.0 5.6 3 2 2 5 5 5 2 AAA domain AAA_16 PF13191.1 EDN04102.1 - 1.7e-13 50.9 0.6 2e-05 24.6 0.0 4.1 2 2 2 4 4 4 2 AAA ATPase domain RuvB_N PF05496.7 EDN04102.1 - 1.8e-13 50.0 0.0 2.5e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EDN04102.1 - 2.4e-11 43.8 0.0 4.1e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EDN04102.1 - 2.6e-11 43.4 0.2 0.00075 19.2 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EDN04102.1 - 1.5e-10 41.9 0.0 1.9e-05 25.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EDN04102.1 - 3.5e-10 39.9 0.0 0.00016 21.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EDN04102.1 - 8.8e-10 38.5 0.0 0.00047 20.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EDN04102.1 - 1.9e-09 36.8 0.0 0.0018 17.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EDN04102.1 - 6.2e-09 35.0 0.0 9.4e-05 21.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EDN04102.1 - 1.9e-08 33.9 0.3 0.0085 15.8 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain RNA_helicase PF00910.17 EDN04102.1 - 5.2e-08 33.0 0.0 0.0044 17.1 0.0 2.7 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 EDN04102.1 - 1.7e-07 30.8 0.4 0.019 14.4 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 EDN04102.1 - 2.7e-07 30.6 0.0 0.0079 16.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EDN04102.1 - 3.5e-07 29.5 0.5 0.018 14.1 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EDN04102.1 - 6.3e-07 29.7 0.0 0.0078 16.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EDN04102.1 - 7.9e-07 28.7 0.0 0.0029 17.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EDN04102.1 - 1e-06 28.5 0.3 0.12 12.0 0.0 3.9 3 1 1 4 4 4 2 NACHT domain AAA_25 PF13481.1 EDN04102.1 - 2.5e-06 27.0 4.5 1 8.7 0.1 4.4 2 2 2 4 4 4 3 AAA domain KaiC PF06745.8 EDN04102.1 - 2.4e-05 23.5 0.2 0.56 9.2 0.0 3.5 3 1 0 4 4 4 2 KaiC Cytidylate_kin2 PF13189.1 EDN04102.1 - 2.5e-05 24.2 0.0 0.003 17.5 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family Sigma54_activ_2 PF14532.1 EDN04102.1 - 4.7e-05 23.4 0.0 0.38 10.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EDN04102.1 - 6.2e-05 23.3 0.0 0.38 11.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.21 EDN04102.1 - 7.8e-05 22.2 0.0 0.27 10.6 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain SKI PF01202.17 EDN04102.1 - 0.00011 22.1 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 2 Shikimate kinase PhoH PF02562.11 EDN04102.1 - 0.00011 21.4 0.0 0.25 10.5 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Arch_ATPase PF01637.13 EDN04102.1 - 0.00018 21.3 0.0 1.9 8.1 0.0 3.7 2 2 1 3 3 3 1 Archaeal ATPase AFG1_ATPase PF03969.11 EDN04102.1 - 0.00042 19.2 0.1 0.14 10.9 0.0 2.7 2 1 0 2 2 2 1 AFG1-like ATPase NB-ARC PF00931.17 EDN04102.1 - 0.0005 19.0 0.0 0.28 10.0 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.10 EDN04102.1 - 0.00069 18.4 0.0 0.36 9.4 0.0 2.4 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein Parvo_NS1 PF01057.12 EDN04102.1 - 0.0008 18.3 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 EDN04102.1 - 0.00086 19.1 0.0 1.6 8.5 0.0 2.6 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit DUF815 PF05673.8 EDN04102.1 - 0.0016 17.4 0.0 0.044 12.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 EDN04102.1 - 0.0018 17.8 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 EDN04102.1 - 0.0026 17.4 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EDN04102.1 - 0.0026 17.3 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EDN04102.1 - 0.0057 16.3 0.1 2 8.0 0.0 3.1 2 1 0 3 3 3 1 NTPase ATP-synt_ab PF00006.20 EDN04102.1 - 0.0076 15.7 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 EDN04102.1 - 0.013 15.0 0.1 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 EDN04102.1 - 0.015 14.9 0.0 0.33 10.5 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.4 EDN04102.1 - 0.04 12.8 0.0 3.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 EDN04102.1 - 0.065 13.5 0.2 2.4 8.4 0.0 2.8 3 0 0 3 3 2 0 AAA domain IPT PF01745.11 EDN04102.1 - 0.074 12.2 0.1 7 5.7 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KTI12 PF08433.5 EDN04102.1 - 0.11 11.7 0.0 21 4.2 0.0 3.1 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 EDN04102.1 - 0.12 11.9 0.0 14 5.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EDN04102.1 - 0.2 11.1 0.3 44 3.5 0.0 3.2 2 2 1 4 4 3 0 DEAD/DEAH box helicase BOP1NT PF08145.7 EDN04103.1 - 8.4e-103 343.6 4.8 8.4e-103 343.6 3.3 1.4 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.27 EDN04103.1 - 1.1e-25 88.5 9.6 2.6e-10 39.7 0.2 6.6 7 1 0 7 7 7 4 WD domain, G-beta repeat DUF3419 PF11899.3 EDN04103.1 - 0.29 9.8 0.0 0.45 9.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Zn_clus PF00172.13 EDN04104.1 - 2.1e-09 37.1 6.6 4.5e-09 36.0 4.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Leo1 PF04004.8 EDN04105.1 - 1.1e-34 119.6 0.1 1.7e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Leo1-like protein Rhomboid PF01694.17 EDN04106.1 - 3.3e-14 53.1 1.4 7.5e-14 51.9 1.0 1.5 1 0 0 1 1 1 1 Rhomboid family PhoD PF09423.5 EDN04107.1 - 2.6e-10 39.4 0.1 3.5e-10 39.0 0.1 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Gryzun PF07919.7 EDN04108.1 - 1.7e-147 492.1 2.8 2.2e-147 491.7 2.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EDN04108.1 - 1.3e-69 234.4 0.0 1.8e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.2 EDN04108.1 - 0.047 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Abhydrolase_6 PF12697.2 EDN04109.1 - 1.2e-18 67.9 0.2 5.1e-18 65.7 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN04109.1 - 1.8e-08 34.2 0.0 0.0047 16.6 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN04109.1 - 8.6e-06 25.4 0.0 2.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDN04109.1 - 0.099 11.8 0.0 0.85 8.7 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family DivIC PF04977.10 EDN04109.1 - 1.9 8.0 3.7 3.9 7.0 2.6 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF465 PF04325.8 EDN04109.1 - 1.9 8.2 5.0 4.8 6.9 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF465) RTA1 PF04479.8 EDN04110.1 - 2.3e-18 66.5 0.4 4.4e-18 65.5 0.0 1.5 1 1 1 2 2 2 1 RTA1 like protein YqhR PF11085.3 EDN04110.1 - 0.0071 15.9 1.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 2 Conserved membrane protein YqhR tRNA_bind_2 PF13725.1 EDN04111.1 - 0.24 11.5 2.0 2.2 8.4 0.1 2.5 2 0 0 2 2 2 0 Possible tRNA binding domain HTH_33 PF13592.1 EDN04113.1 - 4.3e-09 35.7 0.0 1.4e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_29 PF13551.1 EDN04113.1 - 7.1e-07 29.3 0.0 1.2e-06 28.5 0.0 1.4 1 1 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.10 EDN04113.1 - 2.3e-06 27.3 0.0 5.8e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 EDN04113.1 - 4.2e-06 26.2 0.4 0.0004 19.9 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 EDN04113.1 - 3.3e-05 23.3 0.0 0.00049 19.5 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.1 EDN04113.1 - 0.00073 19.4 0.0 0.062 13.3 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.13 EDN04113.1 - 0.0032 17.1 0.0 0.0052 16.4 0.0 1.4 1 1 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.1 EDN04113.1 - 0.019 15.7 0.0 0.2 12.4 0.0 2.1 1 1 1 2 2 2 0 Homeodomain-like domain Terminase_5 PF06056.7 EDN04113.1 - 0.023 14.2 0.2 0.072 12.6 0.0 1.9 2 1 1 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_IS630 PF01710.11 EDN04113.1 - 0.08 12.6 0.0 0.11 12.1 0.0 1.3 1 1 0 1 1 1 0 Transposase Glutaredoxin PF00462.19 EDN04115.1 - 3e-13 49.5 0.0 9.1e-13 47.9 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.1 EDN04115.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ribosomal_L6 PF00347.18 EDN04116.1 - 2e-09 37.7 0.0 2.7e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L6 DUF3336 PF11815.3 EDN04117.1 - 5.3e-37 126.5 0.0 9.2e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EDN04117.1 - 6e-15 55.7 0.1 1.4e-14 54.4 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase RXT2_N PF08595.6 EDN04118.1 - 2.3e-44 150.8 0.3 2.3e-44 150.8 0.2 2.1 2 0 0 2 2 2 1 RXT2-like, N-terminal PEMT PF04191.8 EDN04119.1 - 1.6e-26 92.4 3.6 3.3e-26 91.4 2.5 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase PXA PF02194.10 EDN04120.1 - 2.9e-49 167.1 0.1 2e-48 164.4 0.0 2.4 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EDN04120.1 - 3.5e-23 81.8 1.1 9.1e-23 80.5 0.0 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EDN04120.1 - 8.3e-17 61.0 1.4 2.7e-16 59.3 1.0 1.9 1 0 0 1 1 1 1 PX domain RGS PF00615.14 EDN04120.1 - 9.8e-07 28.8 0.0 2.5e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain Serglycin PF04360.7 EDN04120.1 - 0.025 14.3 0.9 0.082 12.6 0.1 2.1 2 0 0 2 2 2 0 Serglycin LRR19-TM PF15176.1 EDN04120.1 - 0.42 10.3 1.8 1.4 8.6 0.1 2.7 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain ABC2_membrane_4 PF12730.2 EDN04120.1 - 1.1 8.3 3.7 1.7 7.7 2.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein WD40 PF00400.27 EDN04121.1 - 3.8e-28 96.3 3.6 4.5e-08 32.6 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat tRNA-synt_1g PF09334.6 EDN04123.1 - 3.6e-135 450.6 0.0 4.4e-135 450.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EDN04123.1 - 1.2e-05 23.5 0.1 0.018 13.1 0.0 3.5 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Elongin_A PF06881.6 EDN04123.1 - 0.0033 17.7 1.8 0.0046 17.3 0.3 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A UPF0547 PF10571.4 EDN04123.1 - 0.35 10.5 1.5 2.1 8.1 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Yae1_N PF09811.4 EDN04124.1 - 1.6e-08 33.9 4.2 3.7e-08 32.7 2.9 1.7 1 0 0 1 1 1 1 Essential protein Yae1, N terminal ICE2 PF08426.5 EDN04125.1 - 4.2e-153 509.8 10.7 5e-153 509.5 7.4 1.0 1 0 0 1 1 1 1 ICE2 Endosulfine PF04667.12 EDN04126.1 - 2.9e-06 27.1 0.2 7.1e-06 25.8 0.1 1.7 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Peptidase_S10 PF00450.17 EDN04128.1 - 5.6e-113 378.2 0.0 7.6e-113 377.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EDN04128.1 - 0.066 13.0 0.0 0.37 10.6 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family YukC PF10140.4 EDN04128.1 - 0.25 9.8 0.0 0.4 9.2 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC WD40 PF00400.27 EDN04129.1 - 4.5e-50 165.8 20.8 2.3e-10 39.9 0.3 8.2 8 1 0 8 8 8 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EDN04129.1 - 0.00086 18.7 0.0 0.12 11.8 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Tcp11 PF05794.8 EDN04130.1 - 8.1e-44 150.0 4.3 4.2e-43 147.6 0.1 2.7 2 1 0 2 2 2 1 T-complex protein 11 DUF1446 PF07287.6 EDN04131.1 - 3.5e-65 219.8 0.0 4.2e-42 143.9 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1446) DUF4402 PF14352.1 EDN04131.1 - 0.075 13.5 0.2 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4402) HMA PF00403.21 EDN04132.1 - 1e-14 54.3 0.2 1.3e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF2293 PF10056.4 EDN04133.1 - 5.2e-28 96.8 0.2 1.4e-27 95.5 0.2 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Complex1_LYR PF05347.10 EDN04136.1 - 4.7e-10 39.1 0.2 7.5e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDN04136.1 - 0.0034 17.5 0.7 0.0071 16.5 0.4 1.6 1 1 0 1 1 1 1 Complex1_LYR-like zinc_ribbon_6 PF14599.1 EDN04137.1 - 6.7e-26 89.8 0.7 6.7e-26 89.8 0.5 4.8 6 0 0 6 6 6 1 Zinc-ribbon zf-CHY PF05495.7 EDN04137.1 - 1.3e-14 54.0 20.7 1.3e-14 54.0 14.4 4.8 3 1 0 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 EDN04137.1 - 1e-08 34.8 9.3 1e-08 34.8 6.5 4.3 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDN04137.1 - 1.1e-07 31.3 6.4 1.1e-07 31.3 4.5 6.2 3 3 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN04137.1 - 5.3e-07 29.5 7.3 5.3e-07 29.5 5.1 5.7 4 2 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN04137.1 - 6.8e-05 22.5 9.6 6.8e-05 22.5 6.6 6.9 5 4 1 6 6 6 1 zinc-RING finger domain Rrn6 PF10214.4 EDN04138.1 - 6.1e-78 262.7 0.0 5.4e-69 233.1 0.1 2.1 1 1 1 2 2 2 2 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.7 EDN04139.1 - 6.8e-21 74.0 0.0 1.1e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF4614 PF15391.1 EDN04139.1 - 0.0027 17.5 2.1 0.0043 16.8 0.2 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4614) PNPOx_C PF10590.4 EDN04139.1 - 2.6 7.6 6.0 24 4.5 0.0 3.1 3 0 0 3 3 3 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region WD40 PF00400.27 EDN04140.1 - 2.4e-26 90.6 16.9 7e-11 41.5 0.3 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EDN04140.1 - 0.0056 16.4 0.0 0.027 14.1 0.0 2.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EDN04140.1 - 0.0057 15.7 1.1 2.6 7.0 0.0 3.2 3 1 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.4 EDN04140.1 - 0.031 13.6 5.6 1.3 8.4 0.1 3.3 2 2 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Saf-Nte_pilin PF09460.5 EDN04140.1 - 0.096 12.4 0.9 0.65 9.7 0.2 2.1 2 0 0 2 2 2 0 Saf-pilin pilus formation protein Septin PF00735.13 EDN04141.1 - 7.4e-112 372.9 0.3 8.9e-112 372.7 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EDN04141.1 - 2.1e-06 27.6 0.0 3.5e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EDN04141.1 - 6.5e-06 25.4 0.0 1.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EDN04141.1 - 5.4e-05 22.4 0.0 9.8e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDN04141.1 - 0.00062 19.6 0.4 1.4 8.7 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EDN04141.1 - 0.00073 19.0 0.2 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EDN04141.1 - 0.0054 16.2 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 EDN04141.1 - 0.0087 16.4 0.0 0.013 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDN04141.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EDN04141.1 - 0.013 15.8 0.7 0.02 15.2 0.5 1.8 1 1 0 1 1 1 0 ABC transporter T2SE PF00437.15 EDN04141.1 - 0.03 13.2 0.0 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 EDN04141.1 - 0.032 13.0 0.0 0.057 12.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 EDN04141.1 - 0.037 14.0 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EDN04141.1 - 0.038 13.4 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 EDN04141.1 - 0.072 12.2 0.1 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EDN04141.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.16 EDN04142.1 - 3.3e-66 222.2 0.0 3.7e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 EDN04142.1 - 1.9e-07 31.0 0.0 5.5e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN04142.1 - 4.4e-07 30.0 0.0 7.7e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN04142.1 - 4.2e-06 26.9 0.0 0.00014 22.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EDN04142.1 - 2.9e-05 24.0 0.0 4.8e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EDN04142.1 - 6.1e-05 23.3 0.1 0.0013 18.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EDN04142.1 - 0.0001 21.5 0.0 0.00018 20.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EDN04142.1 - 0.00012 22.8 0.4 0.00049 20.9 0.3 2.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EDN04142.1 - 0.00029 21.1 0.0 0.00066 19.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 EDN04142.1 - 0.0012 18.6 0.0 0.002 18.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EDN04142.1 - 0.0014 18.0 0.0 0.0037 16.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EDN04142.1 - 0.0016 18.4 0.2 0.0054 16.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain Miro PF08477.8 EDN04142.1 - 0.0027 18.1 0.0 0.0043 17.5 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein AAA_10 PF12846.2 EDN04142.1 - 0.0047 16.4 0.0 0.013 14.9 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 EDN04142.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 EDN04142.1 - 0.0057 16.8 0.0 0.076 13.2 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EDN04142.1 - 0.0086 16.2 0.0 0.012 15.8 0.0 1.5 1 1 0 1 1 1 1 RNA helicase cobW PF02492.14 EDN04142.1 - 0.0091 15.4 0.0 0.089 12.2 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EDN04142.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 EDN04142.1 - 0.023 14.2 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EDN04142.1 - 0.025 13.2 0.0 0.029 13.0 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF1895 PF08988.5 EDN04142.1 - 0.026 14.5 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) Arch_ATPase PF01637.13 EDN04142.1 - 0.031 13.9 0.0 0.045 13.4 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase Thymidylate_kin PF02223.12 EDN04142.1 - 0.033 13.5 0.1 0.66 9.3 0.0 2.4 2 1 1 3 3 3 0 Thymidylate kinase NTPase_1 PF03266.10 EDN04142.1 - 0.037 13.7 0.1 0.082 12.6 0.1 1.8 1 1 0 1 1 1 0 NTPase AAA_23 PF13476.1 EDN04142.1 - 0.039 14.2 2.5 0.11 12.8 1.7 1.9 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EDN04142.1 - 0.059 12.8 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 EDN04142.1 - 0.067 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EDN04142.1 - 0.12 11.3 0.0 1.7 7.5 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EDN04142.1 - 0.12 11.9 0.1 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 EDN04142.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region T2SE PF00437.15 EDN04142.1 - 0.14 11.0 0.0 0.33 9.8 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein GRAB PF10375.4 EDN04143.1 - 7.1e-05 22.3 2.4 0.00021 20.8 1.6 1.8 1 1 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 EDN04143.1 - 0.018 14.2 14.8 0.21 10.7 2.9 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Mqo PF06039.10 EDN04143.1 - 0.026 12.7 3.2 0.47 8.5 0.2 2.3 1 1 1 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Mt_ATP-synt_D PF05873.7 EDN04143.1 - 0.11 12.1 10.0 0.018 14.7 3.4 2.2 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) NPV_P10 PF05531.7 EDN04143.1 - 0.47 10.7 20.3 0.18 12.0 1.1 4.4 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein HlyD PF00529.15 EDN04143.1 - 3.9 6.6 33.3 1.4 8.1 6.5 2.6 2 1 0 2 2 2 0 HlyD family secretion protein DUF3367 PF11847.3 EDN04143.1 - 5.3 4.8 4.4 7.9 4.2 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) Baculo_PEP_C PF04513.7 EDN04143.1 - 5.9 6.7 16.6 1.8 8.4 1.0 3.6 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliJ PF02050.11 EDN04143.1 - 8.4 6.4 49.2 7 6.7 6.3 3.8 1 1 4 5 5 5 0 Flagellar FliJ protein DUF814 PF05670.8 EDN04144.1 - 4.3e-07 29.7 0.0 8.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) DAO PF01266.19 EDN04146.1 - 2.2e-46 158.4 0.0 3.3e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EDN04146.1 - 8.7e-05 21.7 0.1 0.0037 16.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDN04146.1 - 0.00019 20.4 2.4 0.004 16.0 1.6 2.2 1 1 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.13 EDN04146.1 - 0.033 13.8 0.1 0.068 12.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EDN04146.1 - 0.085 12.9 0.2 0.3 11.1 0.2 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDN04146.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDN04147.1 - 7.2e-14 51.6 0.0 2e-13 50.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EDN04147.1 - 0.037 12.8 0.0 0.12 11.1 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Ecl1 PF12855.2 EDN04149.1 - 3e-07 29.6 1.2 6.2e-07 28.5 0.8 1.6 1 1 0 1 1 1 1 Life-span regulatory factor CAF-1_p150 PF11600.3 EDN04150.1 - 0.003 16.9 6.6 0.0033 16.8 4.6 1.0 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1777 PF08648.7 EDN04150.1 - 0.55 9.9 11.5 0.59 9.8 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF4603 PF15376.1 EDN04150.1 - 0.64 7.1 4.9 0.7 7.0 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Shugoshin_N PF07558.6 EDN04151.1 - 7.9e-17 60.7 3.7 2.3e-16 59.2 2.6 1.9 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EDN04151.1 - 6.3e-10 38.3 6.6 6.3e-10 38.3 4.6 3.9 4 0 0 4 4 4 1 Shugoshin C terminus PPI_Ypi1 PF07491.6 EDN04152.1 - 7.2e-25 86.3 1.5 2.1e-24 84.9 1.0 1.8 1 1 0 1 1 1 1 Protein phosphatase inhibitor AF-4 PF05110.8 EDN04152.1 - 0.085 10.7 3.0 0.11 10.3 2.1 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MTBP_C PF14920.1 EDN04152.1 - 1.4 8.3 5.5 0.21 11.0 0.5 2.0 2 1 0 3 3 3 0 MDM2-binding DUF3385 PF11865.3 EDN04153.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Adaptin_N PF01602.15 EDN04153.1 - 0.013 13.9 0.0 0.037 12.3 0.0 1.6 1 1 1 2 2 2 0 Adaptin N terminal region C8 PF08742.6 EDN04153.1 - 0.14 12.4 1.2 0.44 10.8 0.0 2.2 3 0 0 3 3 3 0 C8 domain Mac PF12464.3 EDN04154.1 - 7.3e-14 51.5 0.6 1.6e-13 50.4 0.4 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 EDN04154.1 - 7.7e-13 47.3 6.5 1.7e-07 30.4 0.3 3.5 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.13 EDN04154.1 - 1.8e-09 37.3 8.2 3.3e-09 36.5 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.1 EDN04154.1 - 6.1e-09 35.2 6.3 8.7e-07 28.4 0.1 3.1 2 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase ALAD PF00490.16 EDN04155.1 - 2.7e-111 371.5 0.0 3.4e-111 371.2 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CIAPIN1 PF05093.8 EDN04156.1 - 1.5e-33 114.8 4.6 2.7e-33 113.9 3.2 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis HABP4_PAI-RBP1 PF04774.10 EDN04157.1 - 0.016 15.7 1.7 0.025 15.0 1.2 1.5 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family Nucleoporin_C PF03177.9 EDN04159.1 - 4.7e-140 467.8 0.6 5.5e-140 467.6 0.4 1.0 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal zf-UBP PF02148.14 EDN04160.1 - 3.7e-09 36.5 20.3 9.6e-06 25.6 5.3 2.8 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein Rep_fac-A_C PF08646.5 EDN04161.1 - 1.9e-51 173.5 11.2 9.4e-49 164.8 4.4 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EDN04161.1 - 7e-23 80.3 0.0 1.8e-22 79.0 0.0 1.7 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EDN04161.1 - 5.8e-15 54.9 0.1 2e-10 40.3 0.0 3.9 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain PIG-X PF08320.7 EDN04161.1 - 0.056 12.7 0.1 0.098 11.9 0.1 1.3 1 0 0 1 1 1 0 PIG-X / PBN1 ADH_zinc_N PF00107.21 EDN04162.1 - 1.1e-21 76.7 0.0 2.1e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN04162.1 - 1.4e-16 61.5 0.0 2.6e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN04162.1 - 2.5e-10 40.0 0.0 8e-10 38.4 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DEAD PF00270.24 EDN04163.1 - 1.7e-45 154.5 0.0 4.1e-44 150.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN04163.1 - 1.6e-26 91.9 0.0 1e-25 89.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN04163.1 - 6.5e-06 26.1 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDN04163.1 - 6.4e-05 21.8 0.0 9.7e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain CMS1 PF14617.1 EDN04163.1 - 0.021 13.9 0.0 0.056 12.5 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EDN04163.1 - 0.072 11.4 0.1 1.9 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Rft-1 PF04506.8 EDN04164.1 - 2.5e-86 290.2 5.0 3.2e-86 289.8 3.5 1.0 1 0 0 1 1 1 1 Rft protein OST3_OST6 PF04756.8 EDN04165.1 - 1.3e-20 73.5 4.6 2.1e-20 72.8 3.2 1.3 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EDN04165.1 - 0.027 14.1 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin CD20 PF04103.10 EDN04165.1 - 5 7.0 10.8 1.1 9.2 0.0 3.2 3 0 0 3 3 3 0 CD20-like family DUF3037 PF11236.3 EDN04166.1 - 0.081 12.9 2.3 0.21 11.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) Reo_sigmaC PF04582.7 EDN04166.1 - 0.86 8.7 11.8 0.056 12.6 4.3 1.7 2 1 0 2 2 2 0 Reovirus sigma C capsid protein COG2 PF06148.6 EDN04166.1 - 7.2 6.4 22.2 1 9.2 2.1 3.9 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FtsJ PF01728.14 EDN04167.1 - 4.1e-39 134.4 0.0 5.6e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase ThiF PF00899.16 EDN04168.1 - 1.9e-27 95.7 0.0 3.1e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EDN04168.1 - 0.00053 20.0 0.0 0.0018 18.4 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase PS_Dcarbxylase PF02666.10 EDN04168.1 - 0.042 13.1 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase 2-Hacid_dh_C PF02826.14 EDN04168.1 - 0.079 12.1 0.0 0.31 10.1 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain His_biosynth PF00977.16 EDN04170.1 - 2.7e-47 160.9 0.2 8.2e-47 159.3 0.2 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EDN04170.1 - 2.8e-30 105.2 0.0 4.5e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EDN04170.1 - 5.4e-11 42.4 0.0 2.7e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EDN04170.1 - 1.2e-08 34.7 0.0 2.9e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EDN04170.1 - 0.004 16.6 0.0 0.011 15.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 DWNN PF08783.6 EDN04171.1 - 9.8e-33 111.9 0.1 2.2e-32 110.8 0.1 1.6 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EDN04171.1 - 4.7e-06 25.9 7.3 1.5e-05 24.3 5.1 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EDN04171.1 - 0.016 15.1 1.2 0.016 15.1 0.8 2.1 2 0 0 2 2 2 0 Zinc knuckle Pol_alpha_B_N PF08418.5 EDN04171.1 - 0.036 13.6 15.7 0.089 12.3 10.9 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal MGC-24 PF05283.6 EDN04171.1 - 0.15 11.7 5.5 0.31 10.8 3.8 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) zf-C3HC4 PF00097.20 EDN04171.1 - 0.74 9.5 8.9 1.9 8.2 6.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDN04171.1 - 1.7 8.5 9.7 4.4 7.2 6.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EDN04171.1 - 4 7.3 13.9 0.062 13.1 4.7 1.8 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 EDN04171.1 - 5.8 7.0 15.8 0.2 11.6 5.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN04171.1 - 8 6.2 14.6 0.67 9.7 6.0 2.2 2 1 0 2 2 2 0 zinc-RING finger domain ATG22 PF11700.3 EDN04172.1 - 7.9e-154 512.6 5.0 1e-153 512.3 3.5 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EDN04172.1 - 2.7e-06 26.3 37.0 0.00014 20.7 4.1 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily BT1 PF03092.11 EDN04172.1 - 0.00096 17.9 3.9 0.0034 16.1 2.7 1.7 1 1 0 1 1 1 1 BT1 family DUF2498 PF10692.4 EDN04172.1 - 0.16 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2498) MFS_1_like PF12832.2 EDN04172.1 - 0.3 10.9 6.1 5.1 6.9 0.0 2.9 3 0 0 3 3 3 0 MFS_1 like family SWIRM PF04433.12 EDN04173.1 - 8.6e-15 54.6 0.0 1.5e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain Ribonuclease PF00545.15 EDN04173.1 - 0.35 10.9 2.0 3.2 7.8 0.6 2.4 2 0 0 2 2 2 0 ribonuclease CDC50 PF03381.10 EDN04174.1 - 4.6e-66 222.8 0.1 5.5e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family p450 PF00067.17 EDN04175.1 - 4e-21 75.0 0.0 5.7e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SPT16 PF08644.6 EDN04176.1 - 1.2e-60 203.8 0.0 3.5e-60 202.2 0.0 1.9 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EDN04176.1 - 2.5e-41 140.9 2.1 2.4e-23 82.4 0.0 3.3 2 1 1 3 3 3 2 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EDN04176.1 - 1.4e-24 86.8 0.0 2.4e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EDN04176.1 - 2.8e-21 75.3 0.2 9.3e-21 73.6 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Mito_carr PF00153.22 EDN04177.1 - 5.1e-20 70.9 0.9 5.3e-13 48.4 0.0 2.8 3 0 0 3 3 3 2 Mitochondrial carrier protein Sugar_tr PF00083.19 EDN04178.1 - 1.3e-99 333.8 16.4 1.4e-99 333.6 11.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN04178.1 - 5.4e-25 87.8 27.1 3.2e-23 82.0 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tmemb_18A PF09771.4 EDN04178.1 - 0.31 11.0 1.4 6.6 6.7 0.0 3.0 3 1 1 4 4 4 0 Transmembrane protein 188 DUF4219 PF13961.1 EDN04180.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) CAP_N PF01213.14 EDN04180.1 - 0.092 12.0 4.5 0.14 11.4 3.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PMT PF02366.13 EDN04183.1 - 1.6e-64 217.6 18.5 4.7e-33 114.5 9.4 3.6 2 2 2 4 4 4 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EDN04183.1 - 2.3e-38 131.6 0.7 3.1e-38 131.2 0.5 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.17 EDN04184.1 - 6e-46 155.7 0.0 2.1e-35 121.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EDN04184.1 - 2.4e-16 60.2 0.0 3.3e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 EDN04184.1 - 3.8e-07 29.5 0.0 1.1e-06 27.9 0.0 1.8 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDN04184.1 - 2.4e-06 27.1 0.0 4.5e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDN04184.1 - 0.00023 20.3 0.0 0.0013 17.9 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EDN04184.1 - 0.0042 17.0 0.0 0.029 14.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase TAT_signal PF10518.4 EDN04184.1 - 0.049 13.6 0.6 0.12 12.4 0.4 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence AAA_22 PF13401.1 EDN04184.1 - 0.064 13.3 0.0 0.61 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3100 PF11299.3 EDN04186.1 - 0.017 14.3 2.2 0.021 14.0 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) DUF2668 PF10873.3 EDN04186.1 - 0.19 11.9 0.4 0.23 11.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) DUF3681 PF12442.3 EDN04186.1 - 3.8 7.7 7.4 12 6.1 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3681) Aldo_ket_red PF00248.16 EDN04188.1 - 9.9e-06 24.5 0.0 1.2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 EDN04189.1 - 1.4e-105 353.4 0.0 1.7e-105 353.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF3296 PF11726.3 EDN04189.1 - 0.041 13.4 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3296) zf-CCHC PF00098.18 EDN04191.1 - 4.6e-41 136.8 47.3 4.9e-09 35.7 1.0 6.7 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_4 PF14392.1 EDN04191.1 - 1.5e-07 30.9 35.9 0.038 13.6 0.4 6.1 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_3 PF13917.1 EDN04191.1 - 0.014 15.0 40.6 0.19 11.5 0.3 5.5 4 1 2 6 6 6 0 Zinc knuckle zf-CCHC_6 PF15288.1 EDN04191.1 - 0.043 13.4 0.9 0.043 13.4 0.6 5.6 5 1 1 6 6 6 0 Zinc knuckle zf-CCHC_2 PF13696.1 EDN04191.1 - 0.76 9.3 26.0 0.75 9.3 0.1 5.4 3 1 2 5 5 5 0 Zinc knuckle F-box PF00646.28 EDN04192.1 - 1.5e-07 30.8 0.0 3.4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN04192.1 - 2.6e-06 27.0 0.1 5.4e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EDN04192.1 - 0.012 15.5 0.6 4.9 7.2 0.0 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Pex16 PF08610.5 EDN04193.1 - 3e-96 322.3 0.4 3e-96 322.3 0.3 2.3 3 0 0 3 3 3 1 Peroxisomal membrane protein (Pex16) SAE2 PF08573.5 EDN04193.1 - 7.4e-30 103.5 0.5 4.8e-29 100.9 0.0 2.7 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF972 PF06156.8 EDN04193.1 - 0.62 10.4 5.3 3.1 8.1 2.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) RNase_HII PF01351.13 EDN04194.1 - 5.2e-47 160.0 0.0 1e-46 159.1 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease HII CENP-C_C PF11699.3 EDN04195.1 - 1.2e-35 121.3 1.1 2.1e-35 120.5 0.7 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 EDN04195.1 - 9.7e-33 113.6 2.0 9.7e-33 113.6 1.4 4.1 3 1 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 EDN04195.1 - 9.2e-07 28.2 0.0 2.4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Myb_DNA-binding PF00249.26 EDN04196.1 - 1.3e-11 44.3 2.2 3.3e-09 36.6 0.1 2.9 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN04196.1 - 2.5e-09 37.1 0.7 3.9e-06 26.8 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Methyltransf_11 PF08241.7 EDN04197.1 - 8.5e-12 45.4 0.0 1.6e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN04197.1 - 2.8e-08 33.6 0.0 6e-08 32.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN04197.1 - 8.2e-06 26.2 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN04197.1 - 0.0002 21.8 0.0 0.00031 21.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN04197.1 - 0.00024 21.3 0.0 0.00085 19.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN04197.1 - 0.017 14.7 0.0 0.037 13.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain ACT_4 PF13291.1 EDN04197.1 - 0.043 14.1 0.1 0.078 13.3 0.0 1.3 1 0 0 1 1 1 0 ACT domain RVT_2 PF07727.9 EDN04198.1 - 3.1e-52 176.9 0.0 4.5e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN04198.1 - 5.9e-15 55.4 0.1 2.2e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EDN04198.1 - 0.023 14.3 0.0 0.061 12.9 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain DUF4219 PF13961.1 EDN04198.1 - 0.023 14.1 1.9 0.048 13.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) CAP_N PF01213.14 EDN04198.1 - 6.6 5.9 9.9 20 4.3 6.9 1.8 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MARVEL PF01284.18 EDN04201.1 - 6.1e-27 94.2 15.5 7.4e-27 93.9 10.8 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF3413 PF11893.3 EDN04201.1 - 2 7.2 8.5 1.7 7.4 4.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3413) EF-hand_4 PF12763.2 EDN04202.1 - 9.5e-39 131.3 0.0 2.3e-15 56.1 0.0 3.9 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EDN04202.1 - 2.3e-11 43.6 0.0 2.4e-06 27.5 0.0 3.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EDN04202.1 - 1.3e-08 33.5 0.2 0.0024 17.0 0.0 5.9 7 0 0 7 7 6 1 EF hand UBA PF00627.26 EDN04202.1 - 2.6e-08 33.4 0.0 5.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_8 PF13833.1 EDN04202.1 - 3.2e-06 26.6 0.2 0.0053 16.3 0.0 3.9 4 0 0 4 4 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EDN04202.1 - 7.5e-05 22.2 0.4 3.3 7.8 0.0 5.3 5 0 0 5 5 5 1 EF-hand domain TPR_MLP1_2 PF07926.7 EDN04202.1 - 0.00021 21.0 23.1 0.014 15.1 8.7 2.5 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 EDN04202.1 - 0.0011 16.7 30.0 0.012 13.3 20.7 1.9 1 1 0 1 1 1 1 Myosin tail Spc7 PF08317.6 EDN04202.1 - 0.0079 14.9 23.1 0.13 10.9 2.5 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EDN04202.1 - 0.029 13.5 8.6 0.0068 15.6 1.5 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ERM PF00769.14 EDN04202.1 - 0.062 12.8 21.4 0.19 11.2 14.8 1.8 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.4 EDN04202.1 - 0.076 12.8 22.5 0.58 10.0 4.4 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF960 PF06124.6 EDN04202.1 - 0.13 12.5 0.0 45 4.3 0.0 3.3 3 0 0 3 3 3 0 Staphylococcal protein of unknown function (DUF960) GAS PF13851.1 EDN04202.1 - 0.18 10.9 23.5 0.31 10.2 6.5 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF812 PF05667.6 EDN04202.1 - 0.27 9.6 20.0 0.36 9.2 13.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Filament PF00038.16 EDN04202.1 - 0.35 10.3 24.8 2.9 7.2 0.4 2.8 1 1 2 3 3 3 0 Intermediate filament protein IncA PF04156.9 EDN04202.1 - 0.79 9.2 27.5 1.1 8.8 14.3 2.2 1 1 1 2 2 2 0 IncA protein FH2 PF02181.18 EDN04202.1 - 0.88 8.3 13.1 0.76 8.5 1.9 2.3 1 1 2 3 3 3 0 Formin Homology 2 Domain MbeD_MobD PF04899.7 EDN04202.1 - 1.1 9.1 19.2 0.52 10.2 4.3 3.7 1 1 2 3 3 3 0 MbeD/MobD like AAA_13 PF13166.1 EDN04202.1 - 1.2 7.4 20.1 3.3 6.0 13.8 1.6 1 1 0 1 1 1 0 AAA domain APG6 PF04111.7 EDN04202.1 - 1.6 7.6 23.8 0.29 10.1 12.7 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 ATG16 PF08614.6 EDN04202.1 - 1.7 8.4 27.0 1 9.1 6.0 3.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-K PF11802.3 EDN04202.1 - 2.4 7.2 8.9 3.9 6.6 6.2 1.2 1 0 0 1 1 1 0 Centromere-associated protein K ADIP PF11559.3 EDN04202.1 - 7 6.5 28.7 10 5.9 3.2 3.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 EDN04202.1 - 7.2 6.4 10.1 2.3 8.0 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tubulin PF00091.20 EDN04203.1 - 2.6e-54 184.3 0.0 4.1e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDN04203.1 - 1.9e-49 166.8 0.1 3.3e-49 166.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EDN04203.1 - 0.0017 17.8 0.0 0.0035 16.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Phage_C PF12025.3 EDN04204.1 - 0.034 14.1 0.1 6.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Phage protein C Pga1 PF10333.4 EDN04205.1 - 0.0024 17.5 0.1 0.11 12.0 0.0 2.3 2 0 0 2 2 2 2 GPI-Mannosyltransferase II co-activator Brix PF04427.13 EDN04207.1 - 1.2e-29 103.3 0.0 1.6e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Brix domain WW PF00397.21 EDN04208.1 - 4e-06 26.5 1.9 8.9e-06 25.4 1.3 1.6 1 0 0 1 1 1 1 WW domain TMEMspv1-c74-12 PF11044.3 EDN04208.1 - 0.22 11.0 0.3 0.33 10.5 0.2 1.2 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein F-box-like PF12937.2 EDN04209.1 - 0.021 14.5 0.3 0.056 13.1 0.2 1.7 1 0 0 1 1 1 0 F-box-like DUF4396 PF14342.1 EDN04210.1 - 1.2e-28 99.9 1.9 1.5e-28 99.6 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Spore_YtrH PF14034.1 EDN04210.1 - 0.074 12.9 0.2 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Sporulation protein YtrH ERCC4 PF02732.10 EDN04213.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.6 1 1 0 1 1 1 0 ERCC4 domain DUF829 PF05705.9 EDN04214.1 - 7.3e-43 146.9 0.0 9.5e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) UFD1 PF03152.9 EDN04215.1 - 6.5e-70 233.8 0.0 8.2e-70 233.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EDN04215.1 - 0.077 12.6 0.0 1.8 8.2 0.0 2.3 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 GYF PF02213.11 EDN04216.1 - 9.1e-13 47.5 1.0 2.1e-12 46.4 0.7 1.6 1 0 0 1 1 1 1 GYF domain ScpA_ScpB PF02616.9 EDN04216.1 - 0.055 13.0 1.4 0.09 12.3 1.0 1.3 1 0 0 1 1 1 0 ScpA/B protein TIP49 PF06068.8 EDN04217.1 - 3.4e-174 579.2 4.1 4e-174 578.9 2.8 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EDN04217.1 - 2.4e-08 33.3 0.2 2e-05 23.7 0.0 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EDN04217.1 - 4.4e-08 33.3 0.1 3.4e-05 24.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 EDN04217.1 - 1.1e-06 27.7 0.3 1.8e-06 27.0 0.2 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EDN04217.1 - 6.5e-05 23.0 0.0 0.0004 20.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN04217.1 - 8.2e-05 22.7 0.0 0.089 12.9 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_25 PF13481.1 EDN04217.1 - 0.0023 17.3 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EDN04217.1 - 0.0036 16.4 1.0 0.045 12.9 0.3 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EDN04217.1 - 0.005 16.7 0.0 2.2 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDN04217.1 - 0.0056 16.3 0.5 0.63 9.7 0.0 3.1 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EDN04217.1 - 0.0092 15.4 0.0 3 7.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 EDN04217.1 - 0.013 15.2 0.4 0.043 13.5 0.2 2.0 1 1 1 2 2 2 0 Part of AAA domain AAA_11 PF13086.1 EDN04217.1 - 0.089 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EDN04217.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Baculo_PEP_C PF04513.7 EDN04218.1 - 5.3e-07 29.5 31.0 0.023 14.5 3.6 4.4 3 1 1 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EDN04218.1 - 1.1e-06 28.1 27.7 1.3e-05 24.5 2.0 3.3 2 1 0 3 3 3 3 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EDN04218.1 - 0.0022 17.7 0.1 0.0022 17.7 0.1 5.3 3 2 1 4 4 3 1 TPR/MLP1/MLP2-like protein DUF869 PF05911.6 EDN04218.1 - 0.064 11.4 47.4 0.22 9.7 15.9 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF869) DUF1664 PF07889.7 EDN04218.1 - 0.2 11.4 36.7 0.23 11.2 2.0 6.1 4 2 2 6 6 6 0 Protein of unknown function (DUF1664) FliD_N PF02465.13 EDN04218.1 - 0.38 11.1 0.1 0.38 11.1 0.1 5.9 2 2 2 4 4 4 0 Flagellar hook-associated protein 2 N-terminus DUF4164 PF13747.1 EDN04218.1 - 0.89 9.7 38.2 0.032 14.3 1.7 6.9 4 1 3 8 8 8 0 Domain of unknown function (DUF4164) Syntaxin PF00804.20 EDN04218.1 - 1.4 9.1 40.1 0.12 12.5 6.0 4.3 3 1 2 5 5 5 0 Syntaxin DUF948 PF06103.6 EDN04218.1 - 1.6 8.6 13.8 1 9.2 0.6 4.8 3 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) YvrJ PF12841.2 EDN04218.1 - 2 7.7 8.7 3.3 7.0 0.0 4.4 5 1 1 6 6 6 0 YvrJ protein family WEMBL PF05701.6 EDN04218.1 - 7.9 4.8 46.0 0.97 7.8 15.5 2.5 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Prefoldin_2 PF01920.15 EDN04218.1 - 8 6.2 40.3 0.31 10.8 0.8 7.5 3 3 3 7 7 7 0 Prefoldin subunit Exo_endo_phos_2 PF14529.1 EDN04224.1 - 6.4e-07 29.0 0.0 1.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF3505 PF12013.3 EDN04227.1 - 4.3e-38 129.8 5.4 1.6e-37 128.0 3.8 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) DUF3505 PF12013.3 EDN04230.1 - 4.4e-15 55.8 0.0 9.5e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) KH_3 PF13014.1 EDN04231.1 - 0.029 14.0 1.6 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 KH domain Nucleoplasmin PF03066.10 EDN04234.1 - 0.16 11.5 4.6 0.18 11.3 3.2 1.1 1 0 0 1 1 1 0 Nucleoplasmin zf-DHHC PF01529.15 EDN04234.1 - 0.28 10.5 1.2 0.34 10.2 0.8 1.0 1 0 0 1 1 1 0 DHHC palmitoyltransferase Trypan_PARP PF05887.6 EDN04234.1 - 0.32 10.7 6.0 0.33 10.7 4.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Borrelia_P83 PF05262.6 EDN04234.1 - 0.37 9.0 2.4 0.39 8.9 1.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein RNA_pol_Rpo13 PF12136.3 EDN04234.1 - 4 7.2 10.2 57 3.5 6.2 2.1 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain DUF3505 PF12013.3 EDN04235.1 - 8.1e-06 26.0 3.7 1.5e-05 25.2 0.3 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) Tom37_C PF11801.3 EDN04235.1 - 2.6 7.8 5.6 0.73 9.6 0.3 2.2 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF4219 PF13961.1 EDN04238.1 - 0.0051 16.2 0.2 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Mito_fiss_reg PF05308.6 EDN04238.1 - 4.4 6.5 16.7 5.5e+02 -0.3 11.5 2.7 1 1 0 1 1 1 0 Mitochondrial fission regulator Helicase_C PF00271.26 EDN04239.1 - 6.5e-14 51.5 0.1 1.6e-13 50.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Acyl-CoA_dh_N PF02771.11 EDN04240.1 - 1.2e-25 90.2 0.6 3.1e-25 88.9 0.1 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EDN04240.1 - 8.1e-25 87.6 0.1 1.3e-24 87.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDN04240.1 - 2.2e-17 62.3 0.0 5e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EDN04240.1 - 2.1e-07 31.2 0.2 3.5e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SEF14_adhesin PF06443.6 EDN04241.1 - 0.00013 21.6 1.7 0.00016 21.3 1.2 1.1 1 0 0 1 1 1 1 SEF14-like adhesin TraT PF05818.7 EDN04241.1 - 0.34 10.3 2.1 0.37 10.1 1.4 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein RVT_2 PF07727.9 EDN04242.1 - 4.1e-07 29.2 0.2 4.3e-07 29.1 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN04243.1 - 8.4e-15 55.2 0.0 1.4e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 RNase H NAD_binding_6 PF08030.7 EDN04244.1 - 0.013 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EDN04244.1 - 0.34 11.0 15.7 0.074 13.1 4.9 3.4 2 2 0 2 2 2 0 Ferric reductase like transmembrane component DDE_1 PF03184.14 EDN04245.1 - 5e-11 42.1 0.0 2.4e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease CK_II_beta PF01214.13 EDN04245.1 - 0.048 13.1 0.1 0.098 12.1 0.0 1.6 1 0 0 1 1 1 0 Casein kinase II regulatory subunit MRP-S26 PF14943.1 EDN04245.1 - 0.059 12.9 11.7 0.035 13.6 5.2 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 HTH_psq PF05225.11 EDN04245.1 - 0.091 12.3 1.2 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 helix-turn-helix, Psq domain NAPRTase PF04095.11 EDN04246.1 - 0.089 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Vps39_1 PF10366.4 EDN04246.1 - 0.099 12.6 0.2 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Cohesin_HEAT PF12765.2 EDN04248.1 - 0.063 13.2 0.9 0.75 9.8 0.1 2.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Methyltransf_23 PF13489.1 EDN04249.1 - 1.7e-10 40.8 0.0 3.8e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN04249.1 - 0.00011 21.8 0.3 0.0068 16.0 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN04249.1 - 0.00056 20.4 0.2 0.038 14.5 0.2 2.5 1 1 0 1 1 1 1 Methyltransferase domain dsDNA_bind PF01984.15 EDN04250.1 - 5.3e-34 116.4 13.0 6.3e-34 116.1 9.0 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 EDN04250.1 - 0.037 14.2 1.0 0.06 13.5 0.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) Imm35 PF15581.1 EDN04250.1 - 0.045 13.7 0.3 0.072 13.1 0.2 1.4 1 0 0 1 1 1 0 Immunity protein 35 FHA PF00498.21 EDN04251.1 - 5.5e-05 23.2 0.4 0.00014 21.8 0.3 1.7 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 EDN04251.1 - 0.022 14.8 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain IMS PF00817.15 EDN04252.1 - 3.9e-41 140.2 0.1 6.8e-41 139.5 0.1 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.3 EDN04252.1 - 8.3e-07 28.7 0.0 3.1e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 IMS family HHH motif DDE_1 PF03184.14 EDN04253.1 - 9.2e-52 175.3 0.0 3e-51 173.6 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease DnaJ-X PF14308.1 EDN04255.1 - 2.5e-57 193.4 6.7 2.5e-57 193.4 4.7 3.1 3 2 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EDN04255.1 - 2.1e-26 91.4 0.2 7.1e-26 89.7 0.2 2.0 1 0 0 1 1 1 1 DnaJ domain HisG_C PF08029.6 EDN04255.1 - 0.0016 18.3 0.1 0.0033 17.3 0.1 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain OrfB_IS605 PF01385.14 EDN04255.1 - 0.046 13.1 3.7 0.11 11.9 2.6 1.5 1 0 0 1 1 1 0 Probable transposase HA PF03457.9 EDN04255.1 - 0.47 10.5 2.8 2.9 8.0 0.5 3.0 3 0 0 3 3 3 0 Helicase associated domain Dicty_REP PF05086.7 EDN04255.1 - 0.9 7.2 5.4 1.5 6.4 3.8 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SQS_PSY PF00494.14 EDN04256.1 - 1.2e-41 142.8 0.0 1.1e-40 139.6 0.0 2.0 2 0 0 2 2 2 1 Squalene/phytoene synthase DUF2207 PF09972.4 EDN04256.1 - 0.0065 15.1 0.0 0.01 14.4 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Fungal_trans PF04082.13 EDN04257.1 - 5.8e-07 28.6 0.0 8e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH PF00378.15 EDN04259.1 - 0.00013 21.1 0.0 0.00019 20.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family RVT_2 PF07727.9 EDN04260.1 - 7.4e-58 195.4 0.0 1.1e-57 194.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Mannosyl_trans PF05007.8 EDN04262.1 - 9.6e-77 258.1 15.2 1.3e-76 257.7 10.6 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EDN04262.1 - 2.1e-13 49.8 4.3 2.1e-13 49.8 2.9 2.0 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EDN04262.1 - 0.00051 19.6 20.9 0.00051 19.6 14.5 3.1 2 2 0 2 2 2 1 Protein of unknown function (DUF2029) Translin PF01997.11 EDN04263.1 - 5e-69 231.9 0.1 5.9e-69 231.6 0.0 1.0 1 0 0 1 1 1 1 Translin family RPEL PF02755.10 EDN04264.1 - 4.2e-28 95.8 14.9 2.5e-10 39.3 0.8 3.4 3 0 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.1 EDN04264.1 - 0.01 16.0 0.4 0.022 15.0 0.1 1.6 1 1 1 2 2 2 0 PPIC-type PPIASE domain DUF2737 PF10930.3 EDN04264.1 - 0.026 14.1 0.8 1.2 8.8 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2737) MEA1 PF06910.6 EDN04264.1 - 0.058 13.0 0.2 0.072 12.7 0.1 1.2 1 0 0 1 1 1 0 Male enhanced antigen 1 (MEA1) Dpy-30 PF05186.8 EDN04264.1 - 0.14 11.7 0.1 0.37 10.3 0.0 1.7 1 0 0 1 1 1 0 Dpy-30 motif DUF4174 PF13778.1 EDN04264.1 - 0.16 12.0 0.9 1.6 8.8 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4174) CP12 PF02672.10 EDN04264.1 - 0.33 11.4 3.7 4.8 7.7 0.2 2.7 3 0 0 3 3 3 0 CP12 domain MCPVI PF02993.9 EDN04264.1 - 0.66 10.0 3.3 0.89 9.6 2.1 1.3 1 1 0 1 1 1 0 Minor capsid protein VI Zip PF02535.17 EDN04265.1 - 1.9e-55 188.0 8.9 2.8e-55 187.5 6.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF872 PF05915.7 EDN04265.1 - 0.18 11.6 1.0 2 8.2 0.0 2.5 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Tom37_C PF11801.3 EDN04266.1 - 9.8e-44 149.1 0.8 1.1e-41 142.5 0.0 2.2 2 0 0 2 2 2 2 Tom37 C-terminal domain Tom37 PF10568.4 EDN04266.1 - 1e-27 96.1 0.3 2.6e-26 91.6 0.0 2.6 3 0 0 3 3 3 1 Outer mitochondrial membrane transport complex protein DUF4366 PF14283.1 EDN04266.1 - 0.017 14.5 1.9 0.026 13.9 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) GST_C_2 PF13410.1 EDN04266.1 - 0.029 14.2 0.2 0.071 13.0 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Nucleoplasmin PF03066.10 EDN04266.1 - 0.23 10.9 6.0 0.37 10.2 4.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin VID27 PF08553.5 EDN04266.1 - 0.39 8.8 1.6 0.53 8.4 1.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DDE_Tnp_1_7 PF13843.1 EDN04267.1 - 4.3e-63 213.4 1.4 1.3e-30 106.6 0.2 2.1 2 0 0 2 2 2 2 Transposase IS4 PBP1_TM PF14812.1 EDN04268.1 - 8.4 6.7 11.6 0.59 10.4 4.3 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NAPRTase PF04095.11 EDN04269.1 - 5.2e-48 163.4 0.3 3.5e-26 91.9 0.1 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family SNARE PF05739.14 EDN04270.1 - 1.9e-11 43.4 7.8 2.3e-11 43.2 3.6 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EDN04270.1 - 3.6e-07 30.2 0.1 3.6e-07 30.2 0.1 2.5 2 1 0 2 2 2 1 Syntaxin Gp-FAR-1 PF05823.7 EDN04270.1 - 0.00012 22.0 1.8 0.0002 21.3 0.1 2.0 1 1 1 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) MCPsignal PF00015.16 EDN04270.1 - 0.009 15.5 6.5 0.027 14.0 3.2 2.1 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-CpG_bind_C PF12269.3 EDN04270.1 - 0.012 15.1 7.6 0.056 12.9 0.2 2.2 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain Gag_p30 PF02093.11 EDN04270.1 - 0.027 13.6 0.0 0.068 12.3 0.0 1.7 1 0 0 1 1 1 0 Gag P30 core shell protein COG5 PF10392.4 EDN04270.1 - 0.043 13.7 1.4 2.4 8.1 0.1 2.5 2 1 0 2 2 2 0 Golgi transport complex subunit 5 PTA_PTB PF01515.14 EDN04270.1 - 0.067 12.2 1.4 0.11 11.5 1.0 1.3 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase BLOC1_2 PF10046.4 EDN04270.1 - 0.14 12.3 6.4 0.56 10.3 0.6 3.2 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1542 PF07564.6 EDN04270.1 - 0.41 10.6 6.2 11 6.0 0.0 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) Spectrin PF00435.16 EDN04270.1 - 1 9.6 8.7 1.2 9.4 0.1 2.8 2 1 2 4 4 4 0 Spectrin repeat HisKA_3 PF07730.8 EDN04270.1 - 2.1 8.7 7.0 4.8 7.5 0.1 3.8 3 1 2 5 5 5 0 Histidine kinase SlyX PF04102.7 EDN04270.1 - 3.7 7.9 9.6 0.61 10.4 1.2 3.4 2 1 1 4 4 4 0 SlyX AMP-binding PF00501.23 EDN04271.1 - 1.6e-62 211.3 0.0 2.2e-62 210.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN04271.1 - 1.6e-10 41.7 0.0 3.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.13 EDN04272.1 - 5.3e-60 201.7 0.9 6.4e-60 201.4 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CEP44 PF15007.1 EDN04274.1 - 0.096 12.3 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 RVT_1 PF00078.22 EDN04275.1 - 2.1e-35 122.0 0.0 3.3e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN04275.1 - 1.3e-14 54.7 0.0 3.2e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN04275.1 - 3.5e-12 45.9 0.0 7.7e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_2 PF07727.9 EDN04276.1 - 2.7e-46 157.5 0.1 1.2e-36 125.9 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN04276.1 - 1.5e-12 47.6 0.0 5.6e-12 45.8 0.0 2.0 1 1 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 EDN04276.1 - 0.00027 20.7 4.1 0.00051 19.8 2.8 1.5 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.1 EDN04276.1 - 0.0017 17.9 0.0 0.0062 16.1 0.0 2.0 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 EDN04276.1 - 0.01 15.6 1.1 0.017 14.8 0.0 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type RTC4 PF14474.1 EDN04279.1 - 2.7e-31 108.0 0.0 3.3e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 RTC4-like domain Pkinase_Tyr PF07714.12 EDN04281.1 - 0.075 12.0 0.0 0.21 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase DUF3435 PF11917.3 EDN04283.1 - 1.5e-148 494.9 0.2 2e-148 494.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2_4 PF13894.1 EDN04283.1 - 0.71 10.3 7.4 1.2 9.6 0.7 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Bestrophin PF01062.16 EDN04284.1 - 0.079 11.8 0.4 0.3 10.0 0.1 1.9 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel Zn_clus PF00172.13 EDN04285.1 - 2.4e-08 33.7 8.7 6e-08 32.4 6.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTC4 PF14474.1 EDN04288.1 - 2e-29 102.0 0.0 2.8e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 RTC4-like domain Myb_DNA-bind_6 PF13921.1 EDN04288.1 - 0.00012 22.1 0.7 0.00031 20.7 0.5 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN04288.1 - 0.12 12.4 3.2 0.09 12.8 0.6 2.2 2 1 0 2 2 2 0 Myb-like DNA-binding domain Pkinase PF00069.20 EDN04289.1 - 5.8e-05 22.3 0.0 6.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EDN04289.1 - 0.002 17.2 0.1 0.0029 16.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YolD PF08863.5 EDN04289.1 - 0.023 14.5 0.0 0.078 12.8 0.0 1.8 2 0 0 2 2 2 0 YolD-like protein APH PF01636.18 EDN04289.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family UBA_e1_C PF09358.5 EDN04290.1 - 0.0054 16.8 0.3 0.006 16.7 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain HTH_psq PF05225.11 EDN04290.1 - 0.026 14.0 0.1 0.072 12.6 0.0 1.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN04290.1 - 0.034 13.9 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Pkinase PF00069.20 EDN04292.1 - 7.6e-07 28.5 0.1 1.5e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EDN04292.1 - 0.025 13.9 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EDN04292.1 - 0.072 12.8 0.0 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S5 PF00333.15 EDN04295.1 - 2.4e-28 97.6 3.2 2.4e-28 97.6 1.4 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EDN04295.1 - 1.5e-22 78.6 0.0 2.8e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Bac_rhodopsin PF01036.13 EDN04297.1 - 8.7e-40 136.3 18.6 1.1e-39 136.0 12.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein 7TM_GPCR_Srz PF10325.4 EDN04297.1 - 0.21 10.6 9.7 0.39 9.7 1.0 2.5 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz Trep_Strep PF09605.5 EDN04297.1 - 0.24 11.0 14.0 2.3 7.8 4.7 2.6 2 1 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF1435 PF07256.7 EDN04297.1 - 2.1 8.3 13.4 1.2 9.1 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1435) tRNA-synt_1 PF00133.17 EDN04299.1 - 8.1e-147 489.7 0.0 5.5e-92 308.6 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) UPF0183 PF03676.9 EDN04299.1 - 3.6e-33 114.7 0.0 1e-27 96.8 0.0 3.1 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0183) Anticodon_1 PF08264.8 EDN04299.1 - 3.3e-21 75.6 0.6 6.3e-21 74.7 0.4 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EDN04299.1 - 7.1e-17 61.1 0.0 5.7e-10 38.4 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EDN04299.1 - 0.014 14.7 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.9 EDN04299.1 - 0.025 14.2 2.0 0.058 13.0 1.4 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS tRNA-synt_1d PF00750.14 EDN04299.1 - 0.075 11.8 0.0 0.39 9.4 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EDN04299.1 - 0.12 11.5 0.0 15 4.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Kinesin PF00225.18 EDN04300.1 - 6e-108 360.5 0.0 1.1e-107 359.5 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 EDN04300.1 - 4e-09 36.7 1.0 4e-09 36.7 0.7 4.9 4 1 2 6 6 6 1 Kinesin-associated microtubule-binding DUF3708 PF12501.3 EDN04300.1 - 2.9 7.7 4.2 66 3.2 0.1 3.5 2 1 1 3 3 3 0 Phosphate ATP-binding cassette transporter DUF948 PF06103.6 EDN04300.1 - 3.4 7.5 20.3 1.8 8.4 0.1 5.7 6 0 0 6 6 6 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 EDN04300.1 - 8.6 6.1 23.6 0.055 13.2 0.4 5.9 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus CSS-motif PF12792.2 EDN04301.1 - 0.0056 16.0 1.3 0.25 10.6 0.0 2.6 3 0 0 3 3 3 2 CSS motif domain associated with EAL CCDC84 PF14968.1 EDN04301.1 - 0.025 14.0 1.1 0.04 13.4 0.1 1.7 2 0 0 2 2 2 0 Coiled coil protein 84 CytochromB561_N PF09786.4 EDN04301.1 - 0.059 11.8 1.7 0.09 11.2 1.2 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal zf-Apc11 PF12861.2 EDN04302.1 - 2.3e-46 155.5 8.9 2.9e-46 155.2 6.2 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EDN04302.1 - 1.1e-32 111.9 7.9 1.3e-32 111.6 5.5 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EDN04302.1 - 7.4e-08 32.1 15.9 6.2e-07 29.1 11.0 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDN04302.1 - 9.3e-05 22.3 11.3 0.00076 19.4 7.8 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN04302.1 - 0.00019 21.0 11.7 0.0089 15.6 8.2 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN04302.1 - 0.00051 19.6 11.7 0.0021 17.6 8.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN04302.1 - 0.00095 18.8 12.7 0.0065 16.1 8.9 2.3 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EDN04302.1 - 0.0083 15.6 10.7 0.21 11.2 5.2 2.6 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EDN04302.1 - 0.022 14.6 4.1 0.022 14.6 2.8 2.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-HIT PF04438.11 EDN04302.1 - 0.043 13.4 1.4 0.043 13.4 0.9 2.4 2 0 0 2 2 2 0 HIT zinc finger zf-Nse PF11789.3 EDN04302.1 - 0.14 11.7 3.5 0.27 10.7 2.4 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EDN04302.1 - 0.17 11.8 15.9 2.9 7.9 11.0 3.0 1 1 0 1 1 1 0 FANCL C-terminal domain RecR PF02132.10 EDN04302.1 - 0.57 9.6 5.6 11 5.5 0.1 3.0 3 0 0 3 3 3 0 RecR protein DZR PF12773.2 EDN04302.1 - 0.58 10.0 11.2 5.8 6.8 5.4 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-RING-like PF08746.6 EDN04302.1 - 0.82 9.7 9.2 3.7 7.6 6.4 2.1 1 1 0 1 1 1 0 RING-like domain PHD PF00628.24 EDN04302.1 - 2.2 8.0 12.4 9.7 5.9 8.6 2.1 1 1 0 1 1 1 0 PHD-finger Opy2 PF09463.5 EDN04302.1 - 4.5 7.4 12.7 5.9 7.0 4.0 2.5 2 0 0 2 2 2 0 Opy2 protein zf-HC5HC2H PF13771.1 EDN04302.1 - 7.8 6.7 9.8 24 5.1 6.2 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain RINGv PF12906.2 EDN04302.1 - 8.3 6.5 11.6 23 5.1 7.4 2.2 1 1 0 1 1 1 0 RING-variant domain zf-HC5HC2H_2 PF13832.1 EDN04302.1 - 8.4 6.4 9.6 2.2 8.3 3.4 2.1 1 1 1 2 2 2 0 PHD-zinc-finger like domain Rhodanese PF00581.15 EDN04303.1 - 2.1e-17 63.4 0.0 2.8e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 Rhodanese-like domain Ribosom_S12_S23 PF00164.20 EDN04303.1 - 0.0008 18.8 0.2 0.0018 17.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S12/S23 PIN_4 PF13638.1 EDN04304.1 - 0.0069 16.4 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 PIN domain Cyt-b5 PF00173.23 EDN04305.1 - 2.1e-16 59.4 0.0 2.7e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FKBP_C PF00254.23 EDN04306.1 - 1.5e-31 108.2 0.0 1.8e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Abhydrolase_2 PF02230.11 EDN04309.1 - 4.5e-22 78.5 0.0 2.5e-15 56.5 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EDN04309.1 - 3.2e-08 33.7 0.1 4.3e-07 30.0 0.1 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN04309.1 - 1.3e-06 28.2 0.0 2.3e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EDN04309.1 - 0.00069 19.1 0.0 0.0026 17.2 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EDN04309.1 - 0.01 15.0 0.0 0.019 14.1 0.0 1.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family Acyl_transf_3 PF01757.17 EDN04310.1 - 3.1e-24 85.4 23.1 5.3e-24 84.6 16.0 1.4 1 1 0 1 1 1 1 Acyltransferase family TMEM219 PF14940.1 EDN04310.1 - 0.17 10.9 0.0 0.44 9.6 0.0 1.6 2 0 0 2 2 2 0 Transmembrane 219 Cyclin_N PF00134.18 EDN04311.1 - 1.7e-35 121.3 0.1 3.4e-35 120.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDN04311.1 - 2.4e-12 46.8 0.4 5.1e-12 45.7 0.3 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain DDE_1 PF03184.14 EDN04312.1 - 6e-51 172.6 0.0 1.4e-50 171.4 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN04312.1 - 3.6e-06 26.8 0.0 7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Metallophos_2 PF12850.2 EDN04313.1 - 0.0094 15.8 0.1 0.014 15.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.27 EDN04314.1 - 6e-16 57.6 4.3 0.013 15.3 0.0 8.3 9 0 0 9 9 9 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EDN04314.1 - 2.1e-05 24.1 0.1 0.0032 16.9 0.0 3.3 3 0 0 3 3 3 1 PQQ-like domain F-box PF00646.28 EDN04315.1 - 0.0001 21.8 0.4 0.0004 19.9 0.3 2.0 2 0 0 2 2 2 1 F-box domain Jacalin PF01419.12 EDN04315.1 - 0.0021 17.9 0.0 0.0054 16.6 0.0 1.6 2 0 0 2 2 2 1 Jacalin-like lectin domain F-box-like PF12937.2 EDN04315.1 - 0.0025 17.5 0.2 0.0063 16.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like Rad4 PF03835.10 EDN04317.1 - 5.7e-08 32.2 0.7 9.4e-08 31.5 0.5 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Memo PF01875.12 EDN04318.1 - 1.6e-21 76.4 0.1 1.8e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein ANTH PF07651.11 EDN04321.1 - 2.5e-57 193.7 0.1 3.4e-57 193.2 0.1 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EDN04321.1 - 8.2e-11 41.8 0.3 4.9e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 ENTH domain Grp1_Fun34_YaaH PF01184.14 EDN04322.1 - 5.4e-87 290.5 18.7 6.7e-87 290.2 12.9 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Grp1_Fun34_YaaH PF01184.14 EDN04324.1 - 4.2e-14 52.3 3.7 5.4e-14 51.9 2.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Spore_YabQ PF09578.5 EDN04324.1 - 0.0072 16.2 6.1 0.013 15.4 4.2 1.5 1 0 0 1 1 1 1 Spore cortex protein YabQ (Spore_YabQ) DUF998 PF06197.8 EDN04324.1 - 0.17 11.1 10.9 0.35 10.1 7.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF998) DUF2207 PF09972.4 EDN04324.1 - 0.68 8.4 2.8 0.85 8.1 2.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3784 PF12650.2 EDN04324.1 - 0.98 9.4 9.2 4 7.4 4.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) DUF3040 PF11239.3 EDN04324.1 - 7 6.7 7.8 11 6.2 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) TRAP_alpha PF03896.11 EDN04325.1 - 0.11 11.4 1.0 0.39 9.6 0.7 2.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Cmc1 PF08583.5 EDN04326.1 - 0.033 13.9 1.7 0.079 12.7 1.2 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like WD40 PF00400.27 EDN04329.1 - 1.7e-24 84.7 4.5 1e-07 31.5 0.0 6.5 6 1 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EDN04329.1 - 0.00041 20.1 0.1 0.067 12.9 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 EDN04329.1 - 0.00081 18.8 1.5 0.0026 17.2 0.0 2.7 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.7 EDN04329.1 - 0.57 9.9 6.2 17 5.2 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Metallophos PF00149.23 EDN04330.1 - 5.7e-36 123.7 0.1 7.9e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pneumo_att_G PF05539.6 EDN04330.1 - 3.6 6.8 9.5 7.3 5.8 6.6 1.5 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Abhydrolase_6 PF12697.2 EDN04331.1 - 7.8e-26 91.3 1.6 1.2e-25 90.7 1.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN04331.1 - 0.018 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN04331.1 - 0.04 13.4 0.0 0.072 12.6 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold TGT PF01702.13 EDN04332.1 - 1.6e-86 289.4 0.0 2.2e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylat_synt PF00303.14 EDN04333.1 - 2.6e-92 308.6 0.0 3.1e-92 308.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase zf-AN1 PF01428.11 EDN04334.1 - 9.3e-25 86.2 26.1 3.7e-13 49.1 6.0 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EDN04334.1 - 0.0022 17.8 19.4 0.0028 17.5 2.8 2.4 2 1 0 2 2 2 2 IBR domain Transp_Tc5_C PF04236.10 EDN04334.1 - 0.033 14.4 17.7 0.088 13.0 2.9 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Pex14_N PF04695.8 EDN04335.1 - 0.77 9.8 7.8 0.15 12.1 2.7 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hist_deacetyl PF00850.14 EDN04336.1 - 2.1e-29 102.8 0.1 3.1e-29 102.2 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain R3H-assoc PF13902.1 EDN04338.1 - 3e-19 69.2 11.8 2.4e-10 40.4 0.0 3.1 3 0 0 3 3 3 2 R3H-associated N-terminal domain R3H PF01424.17 EDN04338.1 - 0.0093 15.6 0.0 0.033 13.8 0.0 1.9 1 0 0 1 1 1 1 R3H domain Peptidase_M28 PF04389.12 EDN04339.1 - 5.7e-27 94.6 0.1 1.2e-26 93.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EDN04339.1 - 6.8e-06 25.7 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EDN04339.1 - 0.0033 16.2 0.2 0.56 8.9 0.1 2.4 2 1 0 2 2 2 2 M42 glutamyl aminopeptidase DUF1774 PF08611.5 EDN04340.1 - 4.3e-39 132.5 1.4 4.3e-39 132.5 0.9 1.9 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) MIG-14_Wnt-bd PF06664.7 EDN04340.1 - 0.0023 16.8 1.1 0.0023 16.8 0.7 2.2 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Chitin_synth_1 PF01644.12 EDN04342.1 - 2.6e-84 280.9 0.1 3.8e-84 280.4 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EDN04342.1 - 3e-33 113.3 0.3 6.2e-33 112.3 0.2 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EDN04342.1 - 5.3e-22 77.8 0.8 7.4e-21 74.1 0.0 2.3 1 1 1 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EDN04342.1 - 1.2e-08 34.9 0.6 1.2e-08 34.9 0.4 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDN04342.1 - 4.1e-05 23.4 0.0 9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 zf-Dof PF02701.10 EDN04343.1 - 0.081 12.8 1.5 7.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Dof domain, zinc finger Brr6_like_C_C PF10104.4 EDN04343.1 - 0.13 11.8 0.3 0.15 11.5 0.2 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain AFG1_ATPase PF03969.11 EDN04344.1 - 4.1e-93 312.0 0.0 4.7e-88 295.4 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EDN04344.1 - 9.9e-05 22.3 0.3 0.064 13.2 0.2 3.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EDN04344.1 - 0.0032 17.3 0.0 0.0087 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EDN04344.1 - 0.014 15.6 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN04344.1 - 0.023 14.8 0.0 0.086 12.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDN04344.1 - 0.034 13.8 0.0 0.073 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EDN04344.1 - 0.092 12.9 0.0 0.48 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 EDN04344.1 - 0.1 12.2 0.1 0.68 9.5 0.0 2.4 3 0 0 3 3 3 0 NACHT domain Lactamase_B PF00753.22 EDN04346.1 - 1.8e-25 89.7 0.6 2.7e-25 89.1 0.4 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EDN04346.1 - 2.9e-06 26.9 0.1 4.2e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EDN04346.1 - 0.028 14.1 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain SH3_1 PF00018.23 EDN04348.1 - 3.9e-23 80.5 0.0 3.2e-11 42.4 0.0 3.0 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 EDN04348.1 - 4.7e-15 54.8 0.0 8.4e-07 28.4 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EDN04348.1 - 1.8e-13 50.2 0.0 3.4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EDN04348.1 - 8.7e-10 37.9 0.0 2.4e-05 23.6 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 EDN04348.1 - 1.7e-09 37.1 0.1 3.4e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 PB1 domain SAC3_GANP PF03399.11 EDN04349.1 - 3e-69 232.6 0.3 4.7e-69 232.0 0.2 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EDN04349.1 - 6.8e-06 25.9 0.1 2.2e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 EAP30 PF04157.11 EDN04350.1 - 8.2e-53 178.8 0.0 1.1e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EDN04350.1 - 5.2e-29 99.8 0.0 8.5e-29 99.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.10 EDN04350.1 - 0.00031 20.2 3.9 0.0037 16.7 0.3 2.5 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 EDN04350.1 - 0.00084 18.3 12.3 0.0084 15.1 0.8 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.15 EDN04350.1 - 0.017 14.6 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 GRAM domain DZR PF12773.2 EDN04350.1 - 0.064 13.0 0.3 0.064 13.0 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon Rubredoxin PF00301.15 EDN04350.1 - 9.6 6.1 7.0 6.2 6.7 0.1 3.5 3 1 0 4 4 4 0 Rubredoxin MFS_1 PF07690.11 EDN04351.1 - 2.9e-09 36.0 5.9 4.4e-09 35.5 4.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4404 PF14357.1 EDN04351.1 - 0.2 12.1 2.8 1.6 9.1 0.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) SNARE PF05739.14 EDN04351.1 - 0.95 9.1 7.4 4.5 7.0 0.1 3.3 3 0 0 3 3 3 0 SNARE domain FKBP_C PF00254.23 EDN04355.1 - 3.4e-22 78.2 0.0 8.6e-22 76.9 0.0 1.5 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase MBA1 PF07961.6 EDN04355.1 - 0.052 12.3 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 MBA1-like protein PHP PF02811.14 EDN04357.1 - 1.2e-05 25.1 0.0 3.6e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 PHP domain ACPS PF01648.15 EDN04358.1 - 3e-13 49.5 0.0 3.7e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily AAT PF03417.11 EDN04359.1 - 1.6e-30 106.2 0.0 2.1e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EDN04359.1 - 1.7e-05 25.0 0.0 3.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF2611 PF11022.3 EDN04360.1 - 1.2e-27 95.7 0.0 1.4e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) MTP18 PF10558.4 EDN04361.1 - 5.1e-68 227.6 0.2 8.4e-68 226.9 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2964 PF11177.3 EDN04361.1 - 0.063 13.2 0.2 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) Cys_Met_Meta_PP PF01053.15 EDN04363.1 - 2.3e-140 467.2 0.0 2.7e-140 467.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EDN04363.1 - 1.9e-05 23.5 0.0 3.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EDN04363.1 - 0.00042 19.4 0.0 0.0014 17.7 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 EDN04363.1 - 0.0021 16.4 0.0 0.022 13.0 0.0 2.0 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 EDN04363.1 - 0.021 13.9 0.0 0.081 12.0 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase POTRA_2 PF08479.6 EDN04363.1 - 0.046 13.3 0.0 0.15 11.7 0.0 1.9 1 0 0 1 1 1 0 POTRA domain, ShlB-type AAA PF00004.24 EDN04364.1 - 1.4e-37 128.8 0.0 3e-37 127.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EDN04364.1 - 7.5e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDN04364.1 - 2.2e-05 24.2 0.1 0.00023 20.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDN04364.1 - 2.4e-05 24.4 0.2 0.00065 19.7 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDN04364.1 - 2.7e-05 24.3 0.3 0.00065 19.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN04364.1 - 3.1e-05 24.7 0.0 9.1e-05 23.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EDN04364.1 - 4.8e-05 22.5 0.0 7.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EDN04364.1 - 0.00014 21.7 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EDN04364.1 - 0.00023 20.6 0.0 0.00051 19.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EDN04364.1 - 0.00037 19.9 0.1 0.036 13.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDN04364.1 - 0.0004 20.2 0.0 0.0008 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EDN04364.1 - 0.00084 19.4 0.0 0.0039 17.3 0.0 2.2 2 1 0 2 2 2 1 RNA helicase Sigma54_activ_2 PF14532.1 EDN04364.1 - 0.00085 19.3 0.0 0.0029 17.6 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EDN04364.1 - 0.00093 18.4 0.1 0.0018 17.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EDN04364.1 - 0.0035 17.0 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Parvo_NS1 PF01057.12 EDN04364.1 - 0.0035 16.2 0.0 0.0052 15.7 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 EDN04364.1 - 0.0036 16.4 0.0 0.0071 15.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EDN04364.1 - 0.0038 17.1 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN04364.1 - 0.0045 16.6 0.2 0.027 14.2 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_24 PF13479.1 EDN04364.1 - 0.0069 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDN04364.1 - 0.0076 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EDN04364.1 - 0.014 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 EDN04364.1 - 0.022 14.3 0.4 0.22 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EDN04364.1 - 0.022 15.0 0.5 0.079 13.2 0.0 2.1 2 0 0 2 2 2 0 ABC transporter DUF815 PF05673.8 EDN04364.1 - 0.055 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SKI PF01202.17 EDN04364.1 - 0.055 13.3 0.6 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase CPT PF07931.7 EDN04364.1 - 0.061 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Rad17 PF03215.10 EDN04364.1 - 0.063 11.9 0.0 0.095 11.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EDN04364.1 - 0.077 12.6 0.0 0.26 10.9 0.0 1.7 1 1 1 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 EDN04364.1 - 0.1 11.4 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.13 EDN04364.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 EDN04364.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 EDN04364.1 - 0.16 10.6 0.1 0.31 9.7 0.0 1.5 2 0 0 2 2 2 0 TIP49 C-terminus Csm1 PF12539.3 EDN04365.1 - 1.8e-28 98.8 0.1 7.5e-28 96.8 0.1 2.1 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 IncA PF04156.9 EDN04365.1 - 0.0033 17.0 6.9 0.0033 17.0 4.8 2.9 3 0 0 3 3 3 1 IncA protein Med4 PF10018.4 EDN04365.1 - 0.0041 16.5 2.9 0.0041 16.5 2.0 2.6 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 TMF_DNA_bd PF12329.3 EDN04365.1 - 0.0044 16.8 5.8 0.0044 16.8 4.1 4.3 4 1 1 5 5 5 1 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.1 EDN04365.1 - 0.0086 15.5 13.9 0.0086 15.5 9.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Baculo_PEP_C PF04513.7 EDN04365.1 - 0.21 11.4 6.8 0.14 11.9 3.3 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EDN04365.1 - 0.74 8.9 7.0 0.9 8.6 4.0 1.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 EDN04365.1 - 1.2 8.8 5.4 2.5 7.9 3.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PigN PF04987.9 EDN04366.1 - 3.6e-141 470.8 37.0 1.9e-100 336.6 12.6 2.2 1 1 1 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EDN04366.1 - 3.4e-10 39.8 0.1 3.9e-09 36.3 0.0 2.2 1 1 1 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EDN04366.1 - 1e-08 34.7 0.0 1.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EDN04366.1 - 0.00041 19.8 0.0 0.00067 19.1 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Fungal_trans PF04082.13 EDN04368.1 - 1.2e-31 109.5 0.0 2.5e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EDN04373.1 - 8.4e-61 204.7 5.0 2.2e-31 109.0 0.3 2.4 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EDN04373.1 - 2.7e-29 101.0 0.0 5.6e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EDN04373.1 - 9.6e-28 97.0 0.6 2.2e-14 53.5 0.0 2.3 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.14 EDN04373.1 - 7.3e-06 25.1 0.3 0.00051 19.1 0.3 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EDN04373.1 - 0.0011 18.4 2.6 0.31 10.4 0.0 3.3 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family DAO PF01266.19 EDN04373.1 - 0.022 13.6 1.2 0.042 12.7 0.8 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF4161 PF13722.1 EDN04373.1 - 0.24 11.7 0.7 9.8 6.4 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) DUF543 PF04418.7 EDN04373.1 - 0.37 10.7 3.5 13 5.8 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Yip1 PF04893.12 EDN04375.1 - 1e-12 47.9 20.2 1.7e-12 47.1 14.0 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EDN04375.1 - 0.4 10.3 12.6 0.73 9.4 8.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) 7TM_transglut PF14402.1 EDN04375.1 - 4 6.2 12.0 5.2 5.8 8.3 1.2 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase Ran_BP1 PF00638.13 EDN04376.1 - 8.2e-14 51.6 0.0 2.2e-07 30.9 0.1 2.5 2 0 0 2 2 2 2 RanBP1 domain DEAD PF00270.24 EDN04377.1 - 1.1e-24 86.7 0.0 2e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN04377.1 - 7.7e-11 41.7 0.1 2.2e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EDN04377.1 - 5.3e-10 39.7 0.2 5.2e-09 36.5 0.1 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) Fungal_trans_2 PF11951.3 EDN04378.1 - 3e-10 39.2 0.3 5.3e-10 38.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_2 PF13639.1 EDN04379.1 - 9.3e-15 54.1 6.7 1.5e-14 53.4 4.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDN04379.1 - 2.2e-09 37.2 2.8 4.5e-09 36.2 1.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDN04379.1 - 9.5e-08 31.5 5.8 1.6e-07 30.8 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN04379.1 - 2.7e-07 30.5 5.2 4.2e-07 29.8 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN04379.1 - 4.6e-06 26.2 4.1 7.3e-06 25.6 2.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDN04379.1 - 7.5e-05 22.3 2.8 0.00012 21.6 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDN04379.1 - 0.00032 20.4 2.9 0.0011 18.7 2.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EDN04379.1 - 0.0017 18.3 7.5 0.0027 17.6 5.2 1.4 1 0 0 1 1 1 1 RING-variant domain zf-Nse PF11789.3 EDN04379.1 - 0.019 14.4 2.2 0.047 13.2 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EDN04379.1 - 0.022 14.6 4.1 0.043 13.7 2.8 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 EDN04379.1 - 0.13 11.9 5.4 0.34 10.6 3.8 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 EDN04379.1 - 0.19 11.3 3.4 0.34 10.5 2.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EDN04379.1 - 0.71 9.6 5.5 0.21 11.3 1.4 2.0 2 0 0 2 2 2 0 RING-type zinc-finger RNA_pol_I_TF PF04090.7 EDN04380.1 - 3.4e-09 36.2 0.0 6.8e-08 32.0 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor ECM11 PF15463.1 EDN04381.1 - 8.2e-26 90.9 1.9 1.8e-25 89.8 0.3 2.3 2 0 0 2 2 2 1 Extracellular mutant protein 11 VPS9 PF02204.13 EDN04382.1 - 9.8e-25 86.5 0.1 2.7e-24 85.1 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Lipase_3 PF01764.20 EDN04383.1 - 5.1e-06 26.1 0.0 9.4e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EDN04383.1 - 0.04 13.6 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 EDN04383.1 - 0.059 13.0 0.2 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) PAS_3 PF08447.6 EDN04385.1 - 4e-08 33.2 0.0 7.6e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 EDN04385.1 - 7.7e-07 28.8 0.0 0.02 14.6 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EDN04385.1 - 1.7e-06 28.3 0.0 0.018 15.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 EDN04385.1 - 1.7e-05 24.7 0.0 0.00021 21.2 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EDN04385.1 - 0.0004 20.4 0.0 0.096 12.7 0.0 2.3 2 0 0 2 2 2 2 PAS fold DUF3419 PF11899.3 EDN04386.1 - 2.8e-159 529.8 0.0 4.3e-159 529.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EDN04386.1 - 3.9e-14 52.6 0.0 2.2e-12 46.9 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN04386.1 - 4.7e-10 39.8 0.0 1.2e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN04386.1 - 3.5e-09 37.2 0.0 1.4e-08 35.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN04386.1 - 4.8e-08 33.3 0.0 3.3e-05 24.2 0.0 3.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN04386.1 - 6.6e-08 32.6 0.0 3.5e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN04386.1 - 9.5e-07 28.5 0.0 5.8e-06 25.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN04386.1 - 6.7e-05 22.1 0.0 0.13 11.3 0.0 2.4 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EDN04386.1 - 0.0027 17.2 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EDN04386.1 - 0.0037 16.3 0.0 0.0079 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 EDN04386.1 - 0.0069 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 EDN04386.1 - 0.036 13.4 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.13 EDN04387.1 - 8.1e-34 116.8 0.0 1.1e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EDN04387.1 - 0.00033 20.4 0.0 0.00053 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN04387.1 - 0.0025 18.3 0.0 0.0053 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Mur_ligase_C PF02875.16 EDN04389.1 - 0.021 14.8 0.0 0.061 13.3 0.0 1.8 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Acetyltransf_1 PF00583.19 EDN04389.1 - 0.037 14.0 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN04389.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain A_deaminase PF00962.17 EDN04390.1 - 1.9e-39 135.4 0.0 3.8e-39 134.5 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase ECH PF00378.15 EDN04392.1 - 7.5e-70 234.8 0.1 9.1e-70 234.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EDN04392.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Rer1 PF03248.8 EDN04393.1 - 5.6e-81 270.3 3.6 6.2e-81 270.1 2.5 1.0 1 0 0 1 1 1 1 Rer1 family DUF4400 PF14348.1 EDN04393.1 - 2 7.7 9.0 2.6 7.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Fungal_trans_2 PF11951.3 EDN04394.1 - 0.00051 18.7 0.1 0.00071 18.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Helicase_C PF00271.26 EDN04395.1 - 9.6e-05 22.1 0.4 0.00019 21.2 0.3 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Catalase PF00199.14 EDN04398.1 - 2.9e-186 618.7 0.3 3.5e-186 618.4 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EDN04398.1 - 3.9e-11 42.6 0.3 1.2e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive Sugar_tr PF00083.19 EDN04400.1 - 2.7e-96 322.8 22.9 3.7e-96 322.4 15.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN04400.1 - 5.4e-25 87.8 48.5 1.3e-23 83.2 17.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Arf PF00025.16 EDN04401.1 - 8.1e-75 249.8 0.0 9.2e-75 249.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDN04401.1 - 7.5e-12 44.8 0.0 9.1e-12 44.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EDN04401.1 - 6.4e-11 41.9 0.0 7.5e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EDN04401.1 - 2.1e-10 39.8 1.0 1e-06 27.7 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDN04401.1 - 6.9e-09 35.1 0.0 8.5e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDN04401.1 - 3.4e-08 33.9 0.0 4.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDN04401.1 - 4e-06 26.7 0.0 5.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDN04401.1 - 2.2e-05 23.9 0.0 0.0032 16.9 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EDN04401.1 - 0.0052 16.0 0.4 0.027 13.7 0.3 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3986 PF13143.1 EDN04401.1 - 0.11 12.9 0.2 0.25 11.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Actin PF00022.14 EDN04402.1 - 8.3e-31 106.7 0.0 1.8e-16 59.5 0.0 2.9 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EDN04402.1 - 0.00092 17.9 0.0 0.091 11.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Paf1 PF03985.8 EDN04403.1 - 1.8e-36 125.8 0.0 1.1e-25 90.2 0.0 3.0 2 1 0 2 2 2 2 Paf1 RICTOR_N PF14664.1 EDN04404.1 - 9e-139 462.1 0.1 5.9e-138 459.4 0.0 2.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EDN04404.1 - 1.5e-90 302.1 2.2 4e-89 297.4 0.2 3.6 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EDN04404.1 - 1e-44 151.1 0.0 5.9e-43 145.4 0.0 3.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EDN04404.1 - 3.1e-22 78.2 3.0 2.6e-21 75.3 0.1 3.9 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EDN04404.1 - 2.4e-11 43.1 10.5 4.9e-11 42.2 7.3 1.6 1 0 0 1 1 1 1 Hr1 repeat Proteasom_PSMB PF10508.4 EDN04404.1 - 0.00031 19.1 0.1 0.17 10.1 0.0 3.7 3 1 1 4 4 4 1 Proteasome non-ATPase 26S subunit Uricase PF01014.13 EDN04405.1 - 9.7e-83 275.1 1.8 4e-46 156.5 0.3 2.0 2 0 0 2 2 2 2 Uricase Ribosomal_L13 PF00572.13 EDN04406.1 - 1.1e-39 135.3 0.0 1.5e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.14 EDN04407.1 - 6.2e-40 136.2 0.5 7.1e-40 136.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AAR2 PF05282.6 EDN04408.1 - 5.1e-89 298.7 0.0 2.8e-87 293.0 0.0 2.1 1 1 0 1 1 1 1 AAR2 protein Ribosomal_S11 PF00411.14 EDN04409.1 - 1e-40 138.3 0.4 1.2e-40 138.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PDH PF02153.12 EDN04410.1 - 2.8e-12 46.1 0.0 4e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase DOMON PF03351.12 EDN04412.1 - 9.9e-05 22.2 0.0 0.00024 21.0 0.0 1.7 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 EDN04412.1 - 0.00026 20.8 9.5 0.00058 19.7 6.6 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EDN04412.1 - 5.6 6.5 7.8 0.24 10.9 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) DUF1516 PF07457.6 EDN04412.1 - 7.3 6.7 8.1 6.7 6.8 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) RRM_6 PF14259.1 EDN04413.1 - 0.0068 16.3 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Paf67 PF10255.4 EDN04414.1 - 1.4e-114 383.1 0.0 1.6e-114 382.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EDN04414.1 - 0.0069 16.2 0.0 0.075 12.9 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDN04414.1 - 0.048 13.2 0.0 0.54 9.9 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDN04414.1 - 0.072 13.0 0.4 0.94 9.4 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Fe-S_biosyn PF01521.15 EDN04415.1 - 8.3e-08 32.1 0.0 2.1e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Hemerythrin PF01814.18 EDN04416.1 - 1.9e-11 44.2 3.4 2.1e-11 44.0 1.8 1.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain MFS_1 PF07690.11 EDN04417.1 - 1.6e-30 106.0 23.9 1.6e-30 106.0 16.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily 2TM PF13239.1 EDN04417.1 - 0.22 11.6 4.0 0.75 9.8 2.8 1.9 1 0 0 1 1 1 0 2TM domain Lactamase_B PF00753.22 EDN04418.1 - 6.5e-10 38.9 0.1 1.2e-07 31.5 0.0 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EDN04418.1 - 0.0058 16.2 0.0 0.0068 15.9 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Adaptin_N PF01602.15 EDN04421.1 - 2e-108 363.0 11.1 2.3e-106 356.2 7.7 2.0 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EDN04421.1 - 1.6e-11 44.2 5.5 0.004 17.4 0.0 5.5 2 2 2 5 5 5 4 HEAT repeats Cnd1 PF12717.2 EDN04421.1 - 1.3e-08 34.9 1.3 5.3e-05 23.1 0.0 4.1 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EDN04421.1 - 8.4e-05 22.3 4.8 0.21 11.7 0.0 5.4 7 0 0 7 7 7 2 HEAT repeat Atx10homo_assoc PF09759.4 EDN04421.1 - 0.00034 20.2 0.1 0.19 11.4 0.0 3.4 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.1 EDN04421.1 - 0.024 15.1 7.8 5.4 7.6 0.1 5.8 4 1 2 6 6 6 0 HEAT-like repeat Arm PF00514.18 EDN04421.1 - 0.037 13.8 5.1 5.8 6.8 0.0 4.6 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF1077 PF06417.7 EDN04422.1 - 2.7e-35 120.4 8.1 9.6e-35 118.6 2.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1077) MFS_1 PF07690.11 EDN04423.1 - 3.6e-38 131.1 14.1 3.6e-38 131.1 9.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN04423.1 - 4.2e-11 42.0 5.5 4.2e-11 42.0 3.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3353 PF11833.3 EDN04423.1 - 5.5e-05 22.7 0.8 0.00011 21.7 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3353) ATG22 PF11700.3 EDN04423.1 - 0.00083 17.9 0.9 0.00083 17.9 0.6 3.3 3 1 1 4 4 4 2 Vacuole effluxer Atg22 like TRI12 PF06609.8 EDN04423.1 - 0.0019 16.4 0.7 0.0019 16.4 0.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EDN04423.1 - 0.015 13.4 0.4 0.065 11.2 0.5 1.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SH3_2 PF07653.12 EDN04424.1 - 3.1e-11 42.5 0.1 5.7e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDN04424.1 - 4.5e-10 38.7 0.3 9.9e-10 37.6 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDN04424.1 - 1.3e-09 37.5 0.2 2.4e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain RPAP2_Rtr1 PF04181.8 EDN04425.1 - 4.1e-17 62.0 0.0 8.2e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family Dicty_REP PF05086.7 EDN04425.1 - 0.24 9.1 0.9 0.33 8.6 0.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ribosomal_S17e PF00833.13 EDN04426.1 - 2.6e-58 195.1 0.5 3e-58 194.8 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EDN04426.1 - 0.026 15.1 0.1 0.038 14.6 0.1 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Mit_ribos_Mrp51 PF11709.3 EDN04427.1 - 6.2e-108 360.7 0.0 7.3e-108 360.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit FAT PF02259.18 EDN04428.1 - 1.9e-129 431.6 0.6 1.9e-129 431.6 0.4 1.8 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 EDN04428.1 - 1.3e-63 213.6 2.4 2.8e-60 202.8 1.1 3.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 EDN04428.1 - 4.3e-56 190.0 0.6 8.8e-56 188.9 0.4 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 EDN04428.1 - 8.4e-40 134.9 0.1 6.6e-39 132.0 0.0 2.8 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 EDN04428.1 - 7.1e-18 64.6 8.1 3.6e-05 23.9 0.0 7.1 4 2 4 8 8 7 5 HEAT repeats HEAT_EZ PF13513.1 EDN04428.1 - 2.6e-16 59.5 7.0 9.4e-05 22.7 0.1 10.4 7 2 4 11 11 10 3 HEAT-like repeat FATC PF02260.15 EDN04428.1 - 4.3e-15 54.8 0.3 9.7e-15 53.7 0.2 1.6 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EDN04428.1 - 7.9e-13 47.3 17.9 0.031 14.3 0.0 11.8 13 0 0 13 13 13 3 HEAT repeat Adaptin_N PF01602.15 EDN04428.1 - 3.4e-05 22.3 5.8 1.1 7.5 1.5 5.5 3 2 0 3 3 3 2 Adaptin N terminal region UME PF08064.8 EDN04428.1 - 0.00011 22.1 2.0 8 6.4 0.0 5.9 7 1 1 8 8 7 2 UME (NUC010) domain TPR_7 PF13176.1 EDN04428.1 - 0.047 13.5 0.4 16 5.6 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EDN04428.1 - 0.099 12.7 2.3 35 4.6 0.0 4.3 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EDN04428.1 - 0.5 10.7 8.4 13 6.2 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Methyltransf_18 PF12847.2 EDN04430.1 - 4e-12 46.6 0.0 6.6e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN04430.1 - 4e-10 39.4 0.0 7.6e-10 38.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN04430.1 - 7.2e-09 36.0 0.0 1.2e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN04430.1 - 7.5e-09 35.4 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN04430.1 - 2.3e-08 34.4 0.0 4.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN04430.1 - 1.6e-06 28.3 0.0 3.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EDN04430.1 - 2.1e-06 27.7 0.0 3.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_26 PF13659.1 EDN04430.1 - 4.8e-06 26.5 0.0 8.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN04430.1 - 0.00031 20.1 0.1 0.0007 19.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EDN04430.1 - 0.00054 19.4 0.0 0.00079 18.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase adh_short_C2 PF13561.1 EDN04430.1 - 0.0011 18.8 0.1 0.003 17.3 0.1 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase TehB PF03848.9 EDN04430.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB DREV PF05219.7 EDN04430.1 - 0.033 13.0 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase CMAS PF02353.15 EDN04430.1 - 0.077 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EDN04430.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family KR PF08659.5 EDN04430.1 - 0.098 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 KR domain TPMT PF05724.6 EDN04430.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) NAD_binding_10 PF13460.1 EDN04433.1 - 2.1e-18 66.9 0.0 1.5e-16 60.9 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDN04433.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EDN04433.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DUF3939 PF13075.1 EDN04433.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) Pex24p PF06398.6 EDN04434.1 - 8.9e-38 129.9 12.2 1.2e-37 129.5 8.5 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Pam16 PF03656.8 EDN04435.1 - 4.6e-36 123.4 0.9 5.4e-36 123.1 0.7 1.0 1 0 0 1 1 1 1 Pam16 Aldo_ket_red PF00248.16 EDN04437.1 - 1.8e-77 259.9 0.0 2.5e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3628 PF12300.3 EDN04437.1 - 0.03 14.3 0.1 0.053 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) XRCC4 PF06632.7 EDN04437.1 - 0.19 10.5 0.2 0.3 9.8 0.1 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PAP_assoc PF03828.14 EDN04438.1 - 4.9e-13 48.8 0.1 9.9e-13 47.8 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EDN04438.1 - 1.2e-08 35.1 0.0 8.2e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 Nucleotidyltransferase domain NmrA PF05368.8 EDN04440.1 - 1.1e-41 142.6 0.0 1.7e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN04440.1 - 1.7e-16 60.7 0.1 3.1e-16 59.9 0.0 1.4 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EDN04440.1 - 7.3e-06 24.8 0.0 1.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDN04440.1 - 0.0015 18.0 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EDN04440.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF4357 PF14267.1 EDN04441.1 - 0.013 15.1 0.1 0.024 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) Hydrolase_like2 PF13246.1 EDN04441.1 - 0.14 12.1 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit RNase_H2_suC PF08615.6 EDN04443.1 - 0.033 14.0 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Cauli_DNA-bind PF03310.8 EDN04443.1 - 0.069 13.0 0.2 0.096 12.5 0.2 1.2 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein PRKCSH-like PF12999.2 EDN04444.1 - 1e-40 139.2 12.6 1.1e-38 132.5 8.8 2.6 1 1 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EDN04444.1 - 4e-31 107.5 1.3 1.3e-30 105.9 0.2 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EDN04444.1 - 8.2e-13 48.9 1.0 2.7e-12 47.3 0.7 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.5 EDN04444.1 - 0.0012 18.1 1.9 0.0024 17.1 1.3 1.4 1 0 0 1 1 1 1 Autophagy-related protein 27 Calci_bind_CcbP PF11535.3 EDN04444.1 - 0.018 15.2 0.8 0.52 10.5 0.2 2.9 3 0 0 3 3 3 0 Calcium binding Fib_alpha PF08702.5 EDN04444.1 - 0.12 12.4 2.7 3.3 7.8 0.9 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CbiX PF01903.12 EDN04444.1 - 0.94 9.6 3.3 0.74 9.9 0.5 2.1 3 0 0 3 3 3 0 CbiX SlyX PF04102.7 EDN04444.1 - 2.3 8.6 5.2 1.4 9.3 0.9 2.4 2 0 0 2 2 2 0 SlyX XhlA PF10779.4 EDN04444.1 - 3.6 7.5 5.6 10 6.1 2.3 2.6 2 0 0 2 2 2 0 Haemolysin XhlA Rtf2 PF04641.7 EDN04445.1 - 8.6e-61 205.3 0.4 1.1e-60 205.0 0.3 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EDN04445.1 - 3.5e-09 36.0 0.2 0.0017 17.8 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EDN04445.1 - 3.9e-07 29.6 0.7 1.2e-06 28.1 0.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EDN04445.1 - 0.0015 18.1 0.2 0.003 17.2 0.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EDN04445.1 - 0.0073 16.1 0.9 0.03 14.1 0.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDN04445.1 - 0.033 13.8 0.4 0.072 12.7 0.3 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L50 PF10501.4 EDN04447.1 - 2.9e-31 107.7 0.1 4.9e-31 106.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S Thiolase_N PF00108.18 EDN04448.1 - 9.4e-76 254.2 0.1 1.4e-75 253.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDN04448.1 - 7.2e-46 154.6 0.4 7.2e-46 154.6 0.3 2.2 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EDN04448.1 - 0.018 14.5 2.2 0.033 13.6 0.8 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain DAHP_synth_1 PF00793.15 EDN04450.1 - 1.2e-95 319.3 0.0 1.4e-95 319.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.1 EDN04452.1 - 5.6e-05 22.6 0.0 5.6e-05 22.6 0.0 2.5 3 1 0 3 3 3 1 Cytochrome oxidase c assembly CCP_MauG PF03150.9 EDN04452.1 - 0.007 16.6 0.5 0.014 15.7 0.1 1.6 2 0 0 2 2 2 1 Di-haem cytochrome c peroxidase p450 PF00067.17 EDN04455.1 - 3.5e-48 164.2 0.0 1.6e-47 162.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 TDH PF03347.8 EDN04455.1 - 0.0075 15.8 0.0 0.033 13.7 0.0 1.9 2 0 0 2 2 2 1 Vibrio thermostable direct hemolysin Exo_endo_phos_2 PF14529.1 EDN04458.1 - 2.7e-05 23.7 0.1 5.6e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN04459.1 - 4.6e-06 26.9 0.0 6.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 RNase H DUF1729 PF08354.5 EDN04460.1 - 0.19 11.5 0.6 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) zf-H2C2 PF09337.5 EDN04461.1 - 0.001 18.4 0.1 0.0025 17.2 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 EDN04462.1 - 2.8e-19 69.3 0.0 6.3e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FlxA PF14282.1 EDN04462.1 - 0.89 9.5 10.2 0.62 10.0 2.4 2.3 2 0 0 2 2 2 0 FlxA-like protein DUF3435 PF11917.3 EDN04463.1 - 3.7e-34 118.1 0.0 1.3e-33 116.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) DegS PF05384.6 EDN04464.1 - 5.2e-05 22.5 1.9 6.9e-05 22.1 1.3 1.1 1 0 0 1 1 1 1 Sensor protein DegS zf-C3HC4 PF00097.20 EDN04464.1 - 0.00026 20.5 8.2 0.00052 19.6 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN04464.1 - 0.0006 19.4 9.6 0.00087 18.9 6.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NTR2 PF15458.1 EDN04464.1 - 0.0016 17.7 1.4 0.0017 17.6 0.9 1.0 1 0 0 1 1 1 1 Nineteen complex-related protein 2 zf-RING_5 PF14634.1 EDN04464.1 - 0.0022 17.6 8.0 0.0036 16.9 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Macoilin PF09726.4 EDN04464.1 - 0.0026 16.1 3.4 0.0031 15.8 2.4 1.0 1 0 0 1 1 1 1 Transmembrane protein TMF_TATA_bd PF12325.3 EDN04464.1 - 0.003 17.2 1.5 0.004 16.8 1.0 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF2730 PF10805.3 EDN04464.1 - 0.0036 17.0 0.5 0.0053 16.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) DivIC PF04977.10 EDN04464.1 - 0.008 15.6 2.0 0.013 14.9 1.4 1.4 1 0 0 1 1 1 1 Septum formation initiator Troponin PF00992.15 EDN04464.1 - 0.0092 16.0 5.3 0.012 15.6 3.6 1.1 1 0 0 1 1 1 1 Troponin ADIP PF11559.3 EDN04464.1 - 0.012 15.5 1.8 0.015 15.1 1.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 EDN04464.1 - 0.013 15.4 5.4 0.022 14.7 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Fez1 PF06818.10 EDN04464.1 - 0.014 15.4 1.2 0.017 15.1 0.9 1.1 1 0 0 1 1 1 0 Fez1 Med28 PF11594.3 EDN04464.1 - 0.014 15.6 1.6 0.022 15.0 1.1 1.3 1 1 0 1 1 1 0 Mediator complex subunit 28 FlaC_arch PF05377.6 EDN04464.1 - 0.016 15.1 1.9 4.7 7.1 1.4 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) HALZ PF02183.13 EDN04464.1 - 0.022 14.4 1.5 0.033 13.9 0.6 1.5 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF4618 PF15397.1 EDN04464.1 - 0.027 13.8 1.0 0.034 13.5 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) GOLGA2L5 PF15070.1 EDN04464.1 - 0.029 12.9 0.2 0.033 12.6 0.1 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Fib_alpha PF08702.5 EDN04464.1 - 0.03 14.4 0.7 0.046 13.8 0.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spectrin PF00435.16 EDN04464.1 - 0.03 14.5 0.8 0.041 14.1 0.6 1.2 1 0 0 1 1 1 0 Spectrin repeat RmuC PF02646.11 EDN04464.1 - 0.032 13.0 1.2 0.041 12.7 0.8 1.1 1 0 0 1 1 1 0 RmuC family HAUS5 PF14817.1 EDN04464.1 - 0.036 12.6 2.7 0.043 12.3 1.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 zf-RING_2 PF13639.1 EDN04464.1 - 0.039 13.7 9.4 0.088 12.6 6.5 1.6 1 1 0 1 1 1 0 Ring finger domain DUF641 PF04859.7 EDN04464.1 - 0.042 13.6 1.2 0.055 13.2 0.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.3 EDN04464.1 - 0.045 13.5 1.8 0.076 12.8 1.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 EDN04464.1 - 0.046 13.5 5.0 0.068 13.0 3.5 1.2 1 0 0 1 1 1 0 Tropomyosin like Cep57_CLD PF14073.1 EDN04464.1 - 0.05 13.4 2.3 0.063 13.1 1.6 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 zf-C3HC4_2 PF13923.1 EDN04464.1 - 0.054 13.5 9.2 0.1 12.6 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1192 PF06698.6 EDN04464.1 - 0.067 13.0 3.1 0.087 12.6 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4164 PF13747.1 EDN04464.1 - 0.093 12.8 5.0 0.13 12.3 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF3373 PF11853.3 EDN04464.1 - 0.094 11.2 0.2 0.11 11.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Seryl_tRNA_N PF02403.17 EDN04464.1 - 0.096 12.7 1.8 0.13 12.2 1.2 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FadA PF09403.5 EDN04464.1 - 0.12 12.4 1.8 0.15 12.0 1.2 1.1 1 0 0 1 1 1 0 Adhesion protein FadA Prefoldin_2 PF01920.15 EDN04464.1 - 0.13 12.0 4.3 0.26 11.0 3.0 1.5 1 1 0 1 1 1 0 Prefoldin subunit Bunya_RdRp PF04196.7 EDN04464.1 - 0.13 10.2 0.1 0.16 9.9 0.0 1.0 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase Flg_hook PF02120.11 EDN04464.1 - 0.13 11.9 0.3 0.18 11.5 0.2 1.1 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK SOCS_box PF07525.11 EDN04464.1 - 0.15 11.9 0.9 0.96 9.3 0.2 2.3 2 0 0 2 2 2 0 SOCS box bZIP_1 PF00170.16 EDN04464.1 - 0.2 11.6 5.3 1.6 8.7 3.7 2.1 1 1 0 1 1 1 0 bZIP transcription factor IncA PF04156.9 EDN04464.1 - 0.25 10.9 3.1 0.35 10.4 2.2 1.2 1 0 0 1 1 1 0 IncA protein CENP-Q PF13094.1 EDN04464.1 - 0.32 11.0 6.3 0.81 9.6 4.5 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1843 PF08898.5 EDN04464.1 - 1.3 9.0 4.4 6.2 6.9 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) RNase_H PF00075.19 EDN04465.1 - 1.5e-18 67.3 0.0 3.2e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN04465.1 - 4.1e-05 23.2 0.1 8.9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like YrhC PF14143.1 EDN04465.1 - 0.12 12.3 0.2 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 YrhC-like protein RVT_1 PF00078.22 EDN04466.1 - 3.4e-29 101.7 0.0 6.4e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN04466.1 - 2.7e-18 65.7 0.1 9.1e-18 64.0 0.1 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN04466.1 - 7.3e-18 65.1 0.0 2e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN04466.1 - 0.00017 21.3 0.1 0.00048 19.8 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like PuR_N PF09182.5 EDN04466.1 - 0.016 14.7 0.0 0.052 13.1 0.0 1.8 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal zf-CCHC PF00098.18 EDN04466.1 - 0.017 15.0 4.9 0.05 13.5 3.4 1.8 1 0 0 1 1 1 0 Zinc knuckle AAA_assoc PF14363.1 EDN04469.1 - 0.079 13.0 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA Tegument_dsDNA PF12818.2 EDN04470.1 - 0.03 13.1 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 dsDNA viral tegument protein Acetyltransf_7 PF13508.1 EDN04470.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN04470.1 - 0.13 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RVT_1 PF00078.22 EDN04471.1 - 7e-34 117.0 0.0 1.2e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN04471.1 - 9.8e-24 83.2 0.0 3e-23 81.6 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN04471.1 - 8.6e-17 61.7 0.0 1.9e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EDN04471.1 - 1.5e-09 38.2 0.2 3e-09 37.1 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_3 PF13456.1 EDN04471.1 - 0.00038 20.1 0.0 0.0012 18.5 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase-like zf-C2H2 PF00096.21 EDN04471.1 - 0.19 12.1 0.1 0.19 12.1 0.0 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type HTH_Tnp_Tc5 PF03221.11 EDN04473.1 - 0.016 15.0 0.6 0.027 14.2 0.4 1.5 1 1 0 1 1 1 0 Tc5 transposase DNA-binding domain RVT_1 PF00078.22 EDN04478.1 - 7.9e-35 120.1 0.0 1.6e-34 119.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN04478.1 - 6.9e-15 54.7 0.0 3e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN04478.1 - 0.00052 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Hexokinase_1 PF00349.16 EDN04479.1 - 2e-37 128.5 0.0 3e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EDN04479.1 - 2.7e-37 128.2 0.0 1.2e-29 103.2 0.0 2.4 2 0 0 2 2 2 2 Hexokinase Dicty_REP PF05086.7 EDN04479.1 - 3.4 5.3 5.2 4.8 4.8 3.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2389 PF09493.5 EDN04480.1 - 0.6 10.4 3.5 0.37 11.0 0.8 1.8 1 1 1 2 2 2 0 Tryptophan-rich protein (DUF2389) NDT80_PhoG PF05224.7 EDN04481.1 - 7.6e-37 127.1 0.4 1.7e-36 125.9 0.0 1.9 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_3 PF00933.16 EDN04485.1 - 1.4e-58 198.2 0.0 2.2e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 EDN04485.1 - 6.7e-05 22.8 0.0 0.00038 20.4 0.0 2.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EDN04485.1 - 0.0034 17.5 0.0 0.012 15.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EDN04485.1 - 0.012 15.7 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glucosamine_iso PF01182.15 EDN04486.1 - 1.5e-17 63.9 0.0 2.3e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Aldedh PF00171.17 EDN04487.1 - 2.3e-157 524.0 0.1 2.7e-157 523.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.17 EDN04488.1 - 9.1e-51 172.8 0.0 4.7e-49 167.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 EDN04490.1 - 5.1e-49 167.0 0.0 6.5e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN04490.1 - 1.2e-39 135.8 0.0 1.8e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EDN04490.1 - 3.2e-06 26.3 0.2 0.00011 21.2 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDN04490.1 - 1.7e-05 23.9 0.0 2.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EDN04490.1 - 0.0001 22.2 0.1 0.0003 20.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDN04490.1 - 0.0002 20.3 0.0 0.11 11.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 EDN04490.1 - 0.0058 15.3 0.0 0.0083 14.8 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EDN04490.1 - 0.016 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN04490.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EDN04490.1 - 0.087 11.8 0.5 0.68 8.9 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EDN04490.1 - 0.11 11.5 0.1 0.71 8.9 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Hydrophobin PF01185.13 EDN04491.1 - 1.8e-05 25.0 7.0 8.2e-05 22.9 4.9 1.9 1 1 0 1 1 1 1 Fungal hydrophobin Amidohydro_4 PF13147.1 EDN04493.1 - 1.5e-07 31.7 2.8 8.2e-07 29.3 1.7 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EDN04493.1 - 4.8e-07 29.3 0.1 9.1e-07 28.4 0.1 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EDN04493.1 - 1.2e-05 25.2 0.1 2.4e-05 24.1 0.0 1.6 1 1 1 2 2 2 1 Amidohydrolase family Excalibur PF05901.6 EDN04494.1 - 0.0093 16.2 0.1 1.8 8.9 0.0 2.6 1 1 1 2 2 2 1 Excalibur calcium-binding domain Glypican PF01153.14 EDN04494.1 - 0.066 11.8 3.7 0.065 11.8 2.6 1.0 1 0 0 1 1 1 0 Glypican DUF2201_N PF13203.1 EDN04494.1 - 0.096 11.8 2.8 0.1 11.7 1.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain MFS_1 PF07690.11 EDN04495.1 - 4e-17 61.9 30.0 5.3e-17 61.5 20.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EDN04495.1 - 3.1e-09 36.5 7.2 3.1e-09 36.5 5.0 2.7 2 2 0 2 2 2 1 Ion channel regulatory protein UNC-93 Fungal_trans PF04082.13 EDN04496.1 - 4.1e-36 124.2 1.9 4.1e-36 124.2 1.3 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Secretin_N_2 PF07655.8 EDN04496.1 - 3.6 8.0 14.3 0.15 12.4 2.9 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain FAD_binding_3 PF01494.14 EDN04498.1 - 3.5e-14 52.6 0.1 1.1e-13 51.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EDN04498.1 - 0.016 14.0 0.3 0.12 11.2 0.0 2.3 2 1 1 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EDN04498.1 - 0.057 13.1 0.0 7.6 6.2 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EDN04498.1 - 0.13 12.2 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Kinetocho_Slk19 PF12709.2 EDN04499.1 - 1.1e-21 76.6 10.1 1.1e-21 76.6 7.0 5.0 4 1 1 5 5 5 2 Central kinetochore-associated DUF1664 PF07889.7 EDN04499.1 - 1.5 8.6 11.7 0.16 11.7 1.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF1241 PF06840.6 EDN04499.1 - 1.6 7.9 9.2 1 8.5 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1241) DUF2244 PF10003.4 EDN04500.1 - 0.039 13.3 0.0 0.039 13.3 0.0 2.8 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) RRM_5 PF13893.1 EDN04501.1 - 0.0033 17.2 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 EDN04501.1 - 0.015 14.9 0.1 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain DUF1168 PF06658.7 EDN04502.1 - 0.81 9.1 19.0 2.2 7.8 6.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Peptidase_S49_N PF08496.5 EDN04502.1 - 2.6 7.8 5.9 0.35 10.6 0.9 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Prok_Ub PF14454.1 EDN04503.1 - 0.053 13.1 0.1 1 9.0 0.0 2.8 2 1 1 3 3 3 0 Prokaryotic Ubiquitin IBN_N PF03810.14 EDN04505.1 - 1.8e-13 50.2 3.6 1.6e-12 47.1 0.0 3.9 5 0 0 5 5 5 1 Importin-beta N-terminal domain Cse1 PF08506.5 EDN04505.1 - 1.1e-07 30.7 0.0 3e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Cse1 HEAT_2 PF13646.1 EDN04505.1 - 6.2e-06 26.4 2.2 0.026 14.8 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats Xpo1 PF08389.7 EDN04505.1 - 0.00055 19.8 2.5 0.022 14.6 0.0 4.1 4 0 0 4 4 4 1 Exportin 1-like protein DUF2435 PF10363.4 EDN04505.1 - 0.002 17.9 0.2 0.0093 15.8 0.2 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) DSHCT PF08148.7 EDN04506.1 - 7e-61 204.6 0.5 1.7e-60 203.3 0.3 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EDN04506.1 - 3.1e-20 72.3 0.0 7.5e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN04506.1 - 3e-06 27.0 0.0 8.1e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN04506.1 - 0.0085 15.9 0.1 0.13 12.0 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Choline_transpo PF04515.7 EDN04507.1 - 1.1e-84 284.0 15.3 1.1e-84 284.0 10.6 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF2415 PF10313.4 EDN04508.1 - 6.8e-14 51.2 0.0 1.6e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) HSP70 PF00012.15 EDN04510.1 - 1.7e-265 881.6 14.1 1.9e-265 881.4 9.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDN04510.1 - 1.9e-14 53.0 8.1 3.2e-13 48.9 1.2 2.7 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.11 EDN04510.1 - 8e-05 22.3 0.1 0.00021 20.9 0.1 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EDN04510.1 - 0.00037 20.3 8.6 0.82 9.5 1.3 4.9 2 1 1 3 3 3 2 Cell division protein FtsA AalphaY_MDB PF04611.7 EDN04510.1 - 0.077 12.8 0.4 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 Mating type protein A alpha Y mating type dependent binding region Tom22 PF04281.8 EDN04510.1 - 9.7 5.7 11.4 0.89 9.0 4.1 2.1 1 1 1 2 2 2 0 Mitochondrial import receptor subunit Tom22 Macro_2 PF14519.1 EDN04511.1 - 0.019 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Macro-like domain Methyltransf_16 PF10294.4 EDN04512.1 - 5.5e-12 45.4 0.1 1.7e-07 30.8 0.0 2.7 3 0 0 3 3 3 2 Putative methyltransferase AMP-binding PF00501.23 EDN04514.1 - 3.1e-81 272.8 0.0 4.9e-81 272.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NDT80_PhoG PF05224.7 EDN04515.1 - 2.6e-41 141.6 0.0 5.1e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family YfhO PF09586.5 EDN04515.1 - 0.0099 13.9 0.8 0.015 13.3 0.5 1.1 1 0 0 1 1 1 1 Bacterial membrane protein YfhO eIF3g PF12353.3 EDN04517.1 - 2.8e-46 156.5 1.2 5.3e-46 155.6 0.8 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EDN04517.1 - 2.6e-16 59.0 0.1 4.1e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN04517.1 - 3.8e-12 46.0 0.1 6.8e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN04517.1 - 2.9e-07 30.2 0.1 5.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TIM21 PF08294.6 EDN04519.1 - 1.2e-43 148.2 0.0 1.6e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EDN04519.1 - 1.3e-06 27.8 0.0 3.5e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 CIA30 PF08547.7 EDN04519.1 - 0.016 15.0 0.1 0.055 13.3 0.0 1.7 2 0 0 2 2 2 0 Complex I intermediate-associated protein 30 (CIA30) B12D PF06522.6 EDN04519.1 - 0.074 12.7 1.4 0.11 12.1 0.3 1.9 2 1 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit ArfGap PF01412.13 EDN04520.1 - 6.9e-35 119.3 0.2 1.2e-34 118.5 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3275 PF11679.3 EDN04520.1 - 0.053 13.1 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) IF2_N PF04760.10 EDN04520.1 - 0.087 12.4 0.1 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Pterin_bind PF00809.17 EDN04521.1 - 2.6e-62 209.9 0.0 2.2e-61 206.9 0.0 2.3 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EDN04521.1 - 4.5e-40 136.3 0.0 8.4e-40 135.4 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Aminotran_5 PF00266.14 EDN04522.1 - 3.2e-40 138.0 0.0 5.9e-40 137.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V NMO PF03060.10 EDN04524.1 - 9.9e-70 235.2 0.6 1.2e-69 234.9 0.4 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EDN04524.1 - 1.6e-08 33.8 0.0 5.7e-07 28.7 0.0 2.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EDN04524.1 - 6.3e-07 28.5 1.0 1.2e-06 27.6 0.7 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EDN04524.1 - 1.5e-05 24.1 0.3 2.3e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EDN04524.1 - 0.00047 19.1 0.8 0.00081 18.4 0.6 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Neuroparsin PF07327.6 EDN04525.1 - 0.046 13.9 1.2 2.1 8.6 1.5 2.3 2 1 0 2 2 2 0 Neuroparsin PWI PF01480.12 EDN04526.1 - 1.3e-09 38.0 0.7 3.8e-09 36.5 0.5 1.9 1 0 0 1 1 1 1 PWI domain Chromo PF00385.19 EDN04526.1 - 6.1e-09 35.4 0.1 2.3e-08 33.5 0.1 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RRM_1 PF00076.17 EDN04526.1 - 0.0023 17.5 0.0 0.0049 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN04526.1 - 0.17 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Retrotrans_gag PF03732.12 EDN04527.1 - 0.0063 16.5 0.5 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein Drf_FH3 PF06367.11 EDN04527.1 - 0.069 12.5 0.2 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Diaphanous FH3 Domain Elongin_A PF06881.6 EDN04527.1 - 0.22 11.9 2.1 8.6 6.8 1.5 2.2 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A RVT_1 PF00078.22 EDN04528.1 - 1.3e-19 70.4 0.3 3.8e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2783 PF10932.3 EDN04530.1 - 0.031 13.7 0.1 0.064 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) ALIX_LYPXL_bnd PF13949.1 EDN04530.1 - 0.032 13.2 5.9 0.055 12.4 1.1 2.1 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Syntaxin-6_N PF09177.6 EDN04530.1 - 0.035 14.5 2.7 3.5 8.1 0.1 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.2 EDN04530.1 - 0.047 13.5 4.8 0.52 10.1 0.2 2.1 2 0 0 2 2 2 0 Tropomyosin like Prenyltrans_1 PF13243.1 EDN04530.1 - 0.07 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Prenyltransferase-like Cytochrom_B562 PF07361.6 EDN04530.1 - 0.094 13.1 0.0 16 5.9 0.0 2.4 2 0 0 2 2 2 0 Cytochrome b562 YscO PF07321.7 EDN04530.1 - 0.096 12.5 3.0 0.22 11.3 0.5 2.0 2 0 0 2 2 2 0 Type III secretion protein YscO Spc7 PF08317.6 EDN04530.1 - 0.1 11.2 1.3 0.36 9.4 0.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein HR1 PF02185.11 EDN04530.1 - 0.12 12.1 5.5 7.9 6.3 0.0 3.2 2 1 1 3 3 3 0 Hr1 repeat TBPIP PF07106.8 EDN04530.1 - 0.14 11.7 3.0 2.6 7.5 0.1 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 EDN04530.1 - 0.18 11.6 0.9 1.2 8.9 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.4 EDN04530.1 - 0.52 10.2 4.1 0.3 11.0 0.3 2.1 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DASH_Spc34 PF08657.5 EDN04530.1 - 1.9 8.0 6.6 1.4 8.4 0.8 2.1 2 0 0 2 2 2 0 DASH complex subunit Spc34 SlyX PF04102.7 EDN04530.1 - 2.5 8.5 6.4 21 5.5 0.3 2.5 2 1 0 2 2 2 0 SlyX Tektin PF03148.9 EDN04530.1 - 3.3 6.1 7.8 4.3 5.7 0.2 2.1 2 0 0 2 2 2 0 Tektin family MerR-DNA-bind PF09278.6 EDN04530.1 - 4 7.8 8.0 12 6.3 0.2 3.0 2 1 1 3 3 3 0 MerR, DNA binding F-box PF00646.28 EDN04531.1 - 0.00014 21.4 0.0 0.00032 20.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN04531.1 - 0.0014 18.3 0.1 0.0039 16.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EDN04531.1 - 0.05 13.5 0.0 0.33 10.9 0.0 2.2 2 0 0 2 2 2 0 PRANC domain PTSIIB_sorb PF03830.10 EDN04531.1 - 0.12 12.2 0.0 0.86 9.4 0.0 2.0 2 0 0 2 2 2 0 PTS system sorbose subfamily IIB component DUF390 PF04094.9 EDN04532.1 - 0.0039 15.3 4.5 0.0058 14.7 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF390) OmpH PF03938.9 EDN04532.1 - 0.0046 16.9 2.0 0.0087 16.0 1.4 1.4 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Synaptobrevin PF00957.16 EDN04532.1 - 0.023 14.3 3.3 0.17 11.4 2.7 2.1 2 0 0 2 2 2 0 Synaptobrevin HAUS6_N PF14661.1 EDN04532.1 - 0.27 10.5 10.2 0.48 9.7 7.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DivIVA PF05103.8 EDN04532.1 - 1.2 9.1 11.2 2.6 8.1 7.8 1.5 1 0 0 1 1 1 0 DivIVA protein GAS PF13851.1 EDN04532.1 - 1.3 8.2 11.6 2.8 7.1 8.0 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 EDN04532.1 - 1.3 7.8 10.9 2.2 7.1 7.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 EAP30 PF04157.11 EDN04532.1 - 5.3 6.1 7.3 9.4 5.3 5.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family MAP7 PF05672.6 EDN04532.1 - 5.5 6.3 33.5 12 5.2 23.2 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family APG6 PF04111.7 EDN04532.1 - 8.1 5.3 12.5 14 4.5 8.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4337 PF14235.1 EDN04532.1 - 9.1 6.0 12.1 19 5.0 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PGI PF00342.14 EDN04536.1 - 1.1e-218 726.5 0.4 1.3e-218 726.3 0.3 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Ribosomal_S21 PF01165.15 EDN04538.1 - 5.4e-11 41.7 4.1 9.4e-11 41.0 2.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 PBAN PF05874.6 EDN04538.1 - 0.0045 16.3 0.3 0.0074 15.6 0.2 1.3 1 0 0 1 1 1 1 Pheromone biosynthesis activating neuropeptide (PBAN) Leu_Phe_trans PF03588.9 EDN04538.1 - 0.07 12.2 1.0 0.098 11.7 0.7 1.2 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase DUF605 PF04652.11 EDN04538.1 - 0.88 8.9 11.6 1 8.7 8.0 1.2 1 0 0 1 1 1 0 Vta1 like Rhodanese PF00581.15 EDN04539.1 - 3.1e-11 43.6 0.0 3.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_28 PF02636.12 EDN04540.1 - 8e-84 280.9 0.0 9.9e-84 280.6 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase USP7_ICP0_bdg PF12436.3 EDN04542.1 - 0.065 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 MIF4G PF02854.14 EDN04543.1 - 4.8e-50 169.8 0.0 9.2e-50 168.9 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EDN04543.1 - 3.3e-23 81.3 2.1 1.1e-22 79.7 1.5 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Actin PF00022.14 EDN04544.1 - 3.1e-160 532.9 0.0 3.5e-160 532.7 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EDN04544.1 - 0.036 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fes1 PF08609.5 EDN04545.1 - 1.1e-33 115.6 2.2 3.1e-33 114.1 1.0 2.0 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EDN04545.1 - 7.8e-06 26.0 0.7 3e-05 24.2 0.0 2.1 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 EDN04545.1 - 0.00011 22.6 0.0 0.00037 20.8 0.0 1.9 1 0 0 1 1 1 1 HEAT-like repeat HEAT PF02985.17 EDN04545.1 - 0.016 15.2 0.1 0.097 12.8 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat RICTOR_V PF14668.1 EDN04545.1 - 0.031 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 UPF0220 PF05255.6 EDN04546.1 - 5.5e-68 227.4 2.3 6.1e-68 227.2 1.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) G3P_antiterm PF04309.7 EDN04546.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Vps55 PF04133.9 EDN04548.1 - 4e-44 149.2 6.8 4.4e-44 149.0 4.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 UPF0149 PF03695.8 EDN04548.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) Proteasome PF00227.21 EDN04549.1 - 1.1e-49 168.3 0.1 1.4e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDN04549.1 - 8.4e-12 44.1 0.3 1.4e-11 43.5 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.11 EDN04549.1 - 0.072 12.7 0.4 11 5.7 0.0 3.1 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Lysine_decarbox PF03641.9 EDN04550.1 - 1.6e-27 95.9 0.0 2.6e-27 95.2 0.0 1.4 1 1 0 1 1 1 1 Possible lysine decarboxylase Med6 PF04934.9 EDN04551.1 - 1.3e-43 147.9 0.0 1.8e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component RdRP PF05183.7 EDN04552.1 - 2.6e-142 475.5 0.0 3e-103 346.5 0.0 2.2 1 1 1 2 2 2 2 RNA dependent RNA polymerase Chorismate_bind PF00425.13 EDN04554.1 - 3.1e-65 220.0 0.1 1e-63 215.0 0.0 2.4 2 1 0 2 2 2 1 chorismate binding enzyme GATase PF00117.23 EDN04554.1 - 7.8e-31 107.0 0.0 1.3e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EDN04554.1 - 3.9e-12 46.3 0.0 8e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EDN04554.1 - 6.1e-07 29.1 0.0 1.5e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 DUF3684 PF12449.3 EDN04555.1 - 0 1538.8 0.1 0 1538.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EDN04555.1 - 5.9e-05 22.7 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDN04555.1 - 0.01 15.5 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRAPPC9-Trs120 PF08626.6 EDN04556.1 - 6.9e-138 460.9 0.0 1.7e-137 459.5 0.0 1.7 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Abhydrolase_6 PF12697.2 EDN04557.1 - 5.8e-11 42.7 0.0 8.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN04557.1 - 6.7e-10 38.9 0.0 1.3e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN04557.1 - 4e-05 23.3 0.0 9e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Complex1_LYR_2 PF13233.1 EDN04559.1 - 0.00079 19.8 0.1 0.00091 19.6 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EDN04559.1 - 0.037 13.8 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DUF4618 PF15397.1 EDN04559.1 - 0.089 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) RNA_pol_L_2 PF13656.1 EDN04560.1 - 4.8e-30 102.8 0.0 6.3e-30 102.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EDN04560.1 - 2.9e-10 39.1 0.0 4e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Peptidase_M22 PF00814.20 EDN04562.1 - 1.7e-84 283.5 0.0 2.1e-84 283.2 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Hydantoinase_A PF01968.13 EDN04562.1 - 0.072 12.1 0.0 0.19 10.7 0.0 1.7 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase SET PF00856.23 EDN04563.1 - 4.3e-15 56.4 0.0 7.5e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 EDN04563.1 - 3.2e-10 39.9 0.3 1.8e-09 37.6 0.2 2.1 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding EPL1 PF10513.4 EDN04564.1 - 3e-30 105.6 10.7 2.1e-29 102.8 0.4 2.9 2 1 0 2 2 2 2 Enhancer of polycomb-like Latarcin PF10279.4 EDN04564.1 - 0.49 10.6 4.5 1.1 9.4 1.5 2.5 2 0 0 2 2 2 0 Latarcin precursor EF-hand_1 PF00036.27 EDN04565.1 - 4.5e-19 66.2 12.3 3.1e-08 32.3 0.4 3.2 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.1 EDN04565.1 - 4.5e-14 51.0 7.5 1.9e-07 30.1 0.2 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EDN04565.1 - 6.2e-14 51.8 4.8 3.7e-12 46.2 0.5 2.3 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EDN04565.1 - 6.6e-14 50.4 4.0 6.1e-05 22.5 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 EDN04565.1 - 9.4e-11 41.1 13.7 1e-05 25.0 0.7 3.4 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EDN04565.1 - 0.00018 21.1 5.4 0.04 13.6 0.1 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EDN04565.1 - 0.00025 21.0 0.1 0.00049 20.1 0.0 1.6 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EDN04565.1 - 0.032 14.1 0.1 0.37 10.7 0.0 2.4 2 1 1 3 3 3 0 EF-hand domain Anthrax-tox_M PF09156.5 EDN04565.1 - 0.084 11.9 0.1 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain Methyltransf_23 PF13489.1 EDN04566.1 - 1.8e-07 31.0 0.1 2.2e-05 24.2 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EDN04566.1 - 0.00051 19.6 0.9 0.043 13.3 0.7 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN04566.1 - 0.33 11.5 2.8 13 6.4 0.4 2.6 2 1 1 3 3 3 0 Methyltransferase domain Ribosomal_S9 PF00380.14 EDN04569.1 - 5.7e-35 120.2 0.0 1.1e-34 119.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Myc_target_1 PF15179.1 EDN04569.1 - 0.16 11.5 2.0 0.26 10.8 1.4 1.2 1 0 0 1 1 1 0 Myc target protein 1 EF1G PF00647.14 EDN04570.1 - 2.2e-47 159.1 0.1 4.2e-47 158.2 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EDN04570.1 - 9.8e-12 44.7 0.1 5.2e-11 42.3 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDN04570.1 - 4.1e-08 32.9 0.1 9.8e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EDN04570.1 - 2.9e-07 30.5 0.0 6.5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EDN04570.1 - 9.3e-07 29.2 0.1 1.9e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EDN04570.1 - 3e-06 27.3 0.0 6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDN04570.1 - 0.095 12.7 0.1 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF947 PF06102.7 EDN04571.1 - 3.9e-40 137.3 17.2 3.9e-40 137.3 11.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF947) DNA_pol_phi PF04931.8 EDN04571.1 - 4.7 4.8 15.1 0.12 10.0 6.0 1.6 2 0 0 2 2 2 0 DNA polymerase phi NIF PF03031.13 EDN04572.1 - 2.3e-19 69.6 0.1 4.2e-18 65.5 0.1 2.2 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase AMPKBI PF04739.10 EDN04574.1 - 5.4e-25 87.1 0.3 1.4e-24 85.8 0.0 2.0 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain ABC1 PF03109.11 EDN04576.1 - 6.2e-34 116.5 0.0 1.4e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 EDN04576.1 - 0.13 11.3 0.0 1.9 7.5 0.0 2.2 1 1 0 1 1 1 0 Protein kinase domain Rotamase PF00639.16 EDN04576.1 - 0.2 12.4 0.7 12 6.6 0.4 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain UreF PF01730.11 EDN04577.1 - 1.2e-13 51.4 0.1 2.2e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 UreF BRE1 PF08647.6 EDN04578.1 - 7.6e-28 96.3 11.6 7.6e-28 96.3 8.0 6.5 5 2 1 6 6 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EDN04578.1 - 1.4e-09 37.8 10.7 2.4e-09 37.0 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN04578.1 - 6.4e-09 35.3 8.4 1.1e-08 34.6 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN04578.1 - 8.1e-08 31.7 10.8 1.5e-07 30.9 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN04578.1 - 2.4e-07 30.4 8.3 4.5e-07 29.5 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EDN04578.1 - 3.1e-06 26.8 11.4 5.1e-06 26.1 7.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EDN04578.1 - 1.4e-05 24.7 6.5 3.5e-05 23.4 4.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EDN04578.1 - 0.0019 18.0 7.2 0.0034 17.2 5.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EDN04578.1 - 0.0022 18.0 3.4 0.0066 16.5 1.8 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger Reo_sigmaC PF04582.7 EDN04578.1 - 0.013 14.7 36.3 0.034 13.3 2.2 4.8 1 1 4 5 5 5 0 Reovirus sigma C capsid protein zf-RING_4 PF14570.1 EDN04578.1 - 0.037 13.6 7.7 0.13 11.8 5.4 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 EDN04578.1 - 0.04 13.7 5.6 0.093 12.6 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.1 EDN04578.1 - 0.05 13.1 3.6 0.1 12.1 2.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EDN04578.1 - 0.13 12.0 4.0 0.26 11.1 2.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.2 EDN04578.1 - 1 9.2 6.1 2.5 8.0 4.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon FYVE PF01363.16 EDN04578.1 - 1.4 8.8 12.9 24 4.8 8.4 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2 PF00096.21 EDN04578.1 - 1.7 9.1 8.3 1.5 9.3 0.3 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-Nse PF11789.3 EDN04578.1 - 2.2 7.8 10.2 0.38 10.3 4.3 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF2680 PF10925.3 EDN04578.1 - 4.2 7.3 11.0 1.7 8.5 0.1 4.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) Phage_Gp23 PF10669.4 EDN04579.1 - 0.026 14.6 1.1 0.074 13.1 0.7 1.7 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) TFIIA PF03153.8 EDN04579.1 - 1.8 8.3 16.8 3.3 7.4 11.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1183 PF06682.7 EDN04580.1 - 3e-58 197.9 2.6 5.6e-58 197.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1183) DUF2404 PF10296.4 EDN04580.1 - 0.00019 21.5 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ARD PF03079.9 EDN04581.1 - 7.6e-48 162.4 0.0 9.2e-48 162.1 0.0 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EDN04581.1 - 4.5e-11 42.0 0.1 6.8e-11 41.5 0.1 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EDN04581.1 - 3.2e-06 26.8 0.0 4.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EDN04581.1 - 1.9e-05 24.1 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EDN04581.1 - 0.0011 18.2 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EDN04581.1 - 0.035 13.7 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 Cupin Cupin_8 PF13621.1 EDN04581.1 - 0.067 12.6 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Cupin-like domain GIDA PF01134.17 EDN04582.1 - 3.4e-154 513.4 0.0 4.2e-154 513.1 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EDN04582.1 - 1.7e-16 59.9 0.0 5.8e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EDN04582.1 - 6.2e-07 29.5 0.4 1.6e-06 28.1 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDN04582.1 - 4.3e-05 22.7 3.2 7.3e-05 22.0 2.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EDN04582.1 - 0.00041 19.3 2.1 0.27 10.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EDN04582.1 - 0.0016 18.0 0.5 0.0039 16.7 0.3 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 EDN04582.1 - 0.0042 15.9 2.9 0.0042 15.9 2.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EDN04582.1 - 0.041 14.3 0.3 0.1 13.0 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDN04582.1 - 0.052 12.0 0.9 0.44 8.9 0.4 2.1 2 0 0 2 2 2 0 HI0933-like protein tRNA-synt_1c PF00749.16 EDN04583.1 - 4.8e-94 314.5 0.0 5.9e-94 314.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EDN04583.1 - 6e-30 104.1 0.0 1.3e-29 103.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Sec1 PF00995.18 EDN04584.1 - 4.5e-155 517.4 0.0 5.2e-155 517.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_tran_WecB PF03808.8 EDN04584.1 - 0.014 14.8 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family adh_short PF00106.20 EDN04585.1 - 1.2e-19 70.8 0.0 1.8e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN04585.1 - 3e-12 46.5 0.0 4.5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN04585.1 - 1.8e-07 30.8 0.0 3.9e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EDN04585.1 - 0.00055 18.9 0.0 0.00069 18.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EDN04585.1 - 0.001 18.0 0.0 0.0026 16.7 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EDN04585.1 - 0.0028 16.4 0.1 0.0038 15.9 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EDN04585.1 - 0.0057 15.9 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN04585.1 - 0.02 14.9 0.0 0.062 13.2 0.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding HTH_Tnp_Tc5 PF03221.11 EDN04587.1 - 1.6e-14 53.4 0.1 3.8e-14 52.2 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN04587.1 - 1e-05 24.9 1.2 1.2e-05 24.7 0.1 1.7 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_1 PF01527.15 EDN04587.1 - 0.049 13.5 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Transposase Tyr-DNA_phospho PF06087.7 EDN04588.1 - 2.2e-42 145.2 0.0 3.1e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase ATP-synt_J PF04911.7 EDN04588.1 - 0.086 12.3 0.1 0.42 10.0 0.0 2.1 2 0 0 2 2 2 0 ATP synthase j chain Tyr-DNA_phospho PF06087.7 EDN04589.1 - 6.1e-07 28.4 0.0 1.7e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase ABC2_membrane PF01061.19 EDN04590.1 - 6.8e-91 303.1 65.4 1.4e-46 158.3 14.4 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EDN04590.1 - 2.2e-38 131.6 0.8 7.4e-20 71.6 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 EDN04590.1 - 1.6e-31 108.0 2.7 1.5e-27 95.2 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EDN04590.1 - 5.2e-07 29.6 0.1 2e-06 27.8 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 EDN04590.1 - 1.1e-06 28.8 0.1 0.0018 18.3 0.0 3.1 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EDN04590.1 - 2.1e-06 27.2 0.1 0.027 13.8 0.1 2.7 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EDN04590.1 - 3.4e-06 27.3 0.1 0.0026 18.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 EDN04590.1 - 3.7e-06 26.4 0.1 0.00082 18.8 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EDN04590.1 - 8.4e-06 25.0 0.0 0.00025 20.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EDN04590.1 - 1.1e-05 25.3 0.0 0.027 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EDN04590.1 - 1.5e-05 25.1 0.0 0.012 15.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 EDN04590.1 - 1.9e-05 24.3 0.7 0.096 12.3 0.2 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EDN04590.1 - 3.3e-05 23.4 0.1 0.0076 15.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 EDN04590.1 - 3.8e-05 23.7 0.5 0.0028 17.6 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 EDN04590.1 - 0.00016 20.8 20.1 0.00016 20.8 13.9 3.8 2 2 1 3 3 2 1 ABC-2 family transporter protein NACHT PF05729.7 EDN04590.1 - 0.00046 19.8 0.3 0.14 11.8 0.2 2.6 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 EDN04590.1 - 0.00056 20.7 0.0 0.049 14.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EDN04590.1 - 0.0012 18.8 0.5 0.0099 15.8 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 EDN04590.1 - 0.0018 18.4 0.0 3.7 7.7 0.0 3.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EDN04590.1 - 0.0028 16.5 0.3 0.41 9.4 0.1 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.1 EDN04590.1 - 0.0038 16.8 0.2 0.36 10.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EDN04590.1 - 0.0044 16.2 0.2 0.15 11.2 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDN04590.1 - 0.0051 16.3 3.2 0.028 13.9 0.2 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EDN04590.1 - 0.0069 16.1 0.5 2.6 7.8 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 EDN04590.1 - 0.01 15.7 0.0 0.36 10.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EDN04590.1 - 0.012 15.3 0.0 4 7.0 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 EDN04590.1 - 0.023 14.1 2.0 0.47 9.8 0.2 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_15 PF13175.1 EDN04590.1 - 0.034 13.1 1.3 1.9 7.4 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Miro PF08477.8 EDN04590.1 - 0.034 14.6 0.0 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein T2SE PF00437.15 EDN04590.1 - 0.037 12.9 0.2 0.26 10.1 0.1 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 EDN04590.1 - 0.068 12.7 0.4 2.3 7.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 EDN04590.1 - 0.07 12.4 0.4 0.8 8.9 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein PduV-EutP PF10662.4 EDN04590.1 - 0.081 12.4 0.6 0.77 9.2 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.13 EDN04590.1 - 0.18 11.2 0.0 6.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Septin PF00735.13 EDN04590.1 - 0.19 10.7 3.0 0.29 10.1 0.0 2.4 3 0 0 3 3 2 0 Septin Gti1_Pac2 PF09729.4 EDN04591.1 - 8.3e-63 211.2 0.0 1.4e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Gti1/Pac2 family GluR_Homer-bdg PF10606.4 EDN04593.1 - 0.22 11.4 4.2 1.3 8.9 1.0 2.2 2 0 0 2 2 2 0 Homer-binding domain of metabotropic glutamate receptor gag-asp_proteas PF13975.1 EDN04597.1 - 0.026 14.3 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease MBOAT PF03062.14 EDN04600.1 - 6.3e-31 107.6 3.5 8.8e-31 107.2 2.4 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Abi PF02517.11 EDN04600.1 - 0.95 9.6 7.1 19 5.4 0.2 3.1 3 0 0 3 3 3 0 CAAX protease self-immunity KIAA1328 PF15369.1 EDN04601.1 - 0.52 10.0 2.7 1 9.0 1.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 zf-C2H2_4 PF13894.1 EDN04605.1 - 0.00013 22.0 12.2 0.026 14.8 2.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 EDN04605.1 - 0.003 17.6 5.9 0.046 13.8 2.0 2.7 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EDN04605.1 - 0.0064 16.7 4.5 0.0064 16.7 3.1 4.1 5 0 0 5 5 5 1 Zinc finger, C2H2 type zf-BED PF02892.10 EDN04605.1 - 0.2 11.4 4.4 0.56 10.0 3.0 1.9 1 1 0 1 1 1 0 BED zinc finger rve PF00665.21 EDN04606.1 - 2.5e-20 72.7 0.0 5.6e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EDN04606.1 - 4e-14 52.0 1.1 8.7e-14 50.9 0.7 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 EDN04606.1 - 0.022 14.6 0.7 0.068 13.0 0.1 2.0 1 1 1 2 2 2 0 Polycomb-like MTF2 factor 2 Helicase_C PF00271.26 EDN04608.1 - 3e-14 52.6 0.1 7.4e-14 51.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1388 PF07142.7 EDN04609.1 - 0.00084 18.9 3.9 0.78 9.5 0.2 3.5 2 2 2 4 4 4 4 Repeat of unknown function (DUF1388) Collagen PF01391.13 EDN04609.1 - 1.1 8.8 8.8 0.78 9.3 3.2 2.5 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) DUF3505 PF12013.3 EDN04611.1 - 4.8e-28 97.5 0.2 4.8e-28 97.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 EDN04611.1 - 0.0039 17.3 1.4 0.016 15.3 0.2 2.5 2 0 0 2 2 2 1 C2H2-type zinc-finger domain DUF4219 PF13961.1 EDN04612.1 - 0.002 17.4 0.1 0.0037 16.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) TSP9 PF11493.3 EDN04612.1 - 0.13 12.8 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 Ribul_P_3_epim PF00834.14 EDN04613.1 - 2.2e-57 193.4 0.0 2.8e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 EDN04613.1 - 0.0045 16.5 0.7 0.071 12.6 0.0 2.2 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.19 EDN04613.1 - 0.0048 16.3 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.9 EDN04613.1 - 0.023 13.7 0.1 0.032 13.3 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG SH3BGR PF04908.10 EDN04614.1 - 0.00022 21.1 0.0 0.00059 19.7 0.0 1.8 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein HyaE PF07449.6 EDN04614.1 - 0.076 12.9 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Aa_trans PF01490.13 EDN04616.1 - 1.2e-25 89.9 30.3 1.2e-24 86.6 21.0 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein RVT_1 PF00078.22 EDN04617.1 - 1.4e-21 76.8 0.1 3e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN04617.1 - 1.1e-17 64.2 0.4 3.5e-17 62.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EDN04617.1 - 3.6e-13 48.9 1.0 8.6e-13 47.7 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EDN04617.1 - 0.00016 21.0 0.1 0.00046 19.5 0.0 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Tudor-knot PF11717.3 EDN04617.1 - 0.0029 17.2 0.3 0.029 14.0 0.0 2.6 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain RVP PF00077.15 EDN04617.1 - 0.028 14.3 0.0 0.084 12.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EDN04617.1 - 0.071 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDN04617.1 - 0.14 12.6 0.0 0.32 11.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease Methyltransf_11 PF08241.7 EDN04618.1 - 8.1e-08 32.6 0.0 3.4e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Enoyl_reductase PF12241.3 EDN04618.1 - 0.44 9.4 1.0 1.6 7.6 0.4 1.9 2 0 0 2 2 2 0 Trans-2-enoyl-CoA reductase catalytic region LSM PF01423.17 EDN04619.1 - 3.9e-15 55.1 0.9 5.7e-15 54.6 0.6 1.2 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.3 EDN04619.1 - 0.055 13.2 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) HTH_25 PF13413.1 EDN04619.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DRMBL PF07522.9 EDN04620.1 - 1.2e-34 118.6 0.1 3e-34 117.3 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EDN04620.1 - 3.5e-10 39.7 0.2 8e-10 38.5 0.2 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain zf-BED PF02892.10 EDN04621.1 - 0.014 15.1 5.0 0.47 10.2 0.3 2.6 2 0 0 2 2 2 0 BED zinc finger zf-Di19 PF05605.7 EDN04621.1 - 0.39 10.8 2.3 0.9 9.7 1.6 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EDN04621.1 - 1.4 9.4 7.3 0.21 11.9 1.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1092 PF06485.6 EDN04622.1 - 0.22 10.4 0.7 0.24 10.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) Pro-rich PF15240.1 EDN04622.1 - 8.1 6.5 25.0 10 6.1 17.3 1.1 1 0 0 1 1 1 0 Proline-rich zf-C2H2_4 PF13894.1 EDN04623.1 - 0.01 16.1 0.7 0.01 16.1 0.5 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger Abhydro_lipase PF04083.11 EDN04624.1 - 3.9e-11 42.1 0.0 7.4e-11 41.2 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EDN04624.1 - 0.00073 19.4 0.8 0.0013 18.6 0.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN04624.1 - 0.01 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN04624.1 - 0.034 13.7 0.0 0.069 12.6 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold MS_channel PF00924.13 EDN04625.1 - 9.7e-24 83.8 3.5 2e-23 82.8 2.4 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EDN04625.1 - 0.00035 19.6 0.3 0.00075 18.6 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EDN04625.1 - 0.00093 19.2 0.1 0.0025 17.9 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EDN04625.1 - 0.001 18.7 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EDN04625.1 - 0.0013 17.9 0.0 0.0028 16.9 0.0 1.6 1 0 0 1 1 1 1 EF hand Senescence PF06911.7 EDN04625.1 - 0.026 14.2 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Senescence-associated protein Tubulin PF00091.20 EDN04626.1 - 1.1e-64 218.2 0.0 1.4e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDN04626.1 - 3.6e-44 149.8 0.0 5.5e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EDN04626.1 - 0.00053 19.4 0.0 0.00094 18.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 EDN04626.1 - 0.1 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Mito_carr PF00153.22 EDN04627.1 - 2.7e-64 212.9 0.5 2.9e-21 74.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Spore_YhaL PF14147.1 EDN04627.1 - 0.12 11.8 0.5 2.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Sporulation protein YhaL TauD PF02668.11 EDN04628.1 - 3.9e-54 184.0 0.0 6.2e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EDN04628.1 - 0.078 11.8 0.0 0.21 10.4 0.0 1.6 2 0 0 2 2 2 0 CsiD PhyH PF05721.8 EDN04628.1 - 0.089 12.8 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Glutaredoxin PF00462.19 EDN04629.1 - 2.4e-20 72.2 0.0 5.4e-18 64.7 0.0 2.5 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EDN04629.1 - 1.2e-13 50.6 0.0 3.4e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 EDN04629.1 - 5.8e-05 23.1 0.0 0.0015 18.5 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like TrbC_Ftype PF09673.5 EDN04629.1 - 0.013 15.0 0.0 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_2 PF13098.1 EDN04629.1 - 0.013 15.6 0.1 0.36 11.0 0.0 2.9 2 2 1 3 3 3 0 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EDN04629.1 - 0.023 14.5 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin domain HyaE PF07449.6 EDN04629.1 - 0.083 12.7 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE RNase_T PF00929.19 EDN04630.1 - 4e-24 85.7 0.0 7.4e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Exonuclease TSC22 PF01166.13 EDN04631.1 - 0.018 15.0 1.2 0.56 10.2 0.0 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.10 EDN04631.1 - 0.38 10.2 2.9 16 5.1 0.1 2.8 1 1 1 2 2 2 0 Septum formation initiator Pkinase PF00069.20 EDN04632.1 - 3.4e-39 134.5 0.0 2.8e-25 88.9 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN04632.1 - 3.4e-13 49.2 0.0 9.8e-05 21.5 0.0 3.3 1 1 1 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 EDN04632.1 - 2.6e-08 33.8 0.3 7.2e-08 32.4 0.1 1.9 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EDN04632.1 - 0.045 12.7 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SOG2 PF10428.4 EDN04632.1 - 4.7 5.7 7.1 7.7 5.0 4.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3716 PF12511.3 EDN04634.1 - 3.6e-18 64.9 4.9 7.2e-18 63.9 3.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF2890 PF11081.3 EDN04634.1 - 0.0024 17.9 1.9 0.0033 17.5 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) Sporozoite_P67 PF05642.6 EDN04634.1 - 0.0063 14.4 2.1 0.0076 14.1 1.4 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 EDN04634.1 - 0.016 14.7 0.4 0.022 14.2 0.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin LAT PF15234.1 EDN04634.1 - 0.036 13.5 1.6 0.059 12.8 1.1 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells VESA1_N PF12785.2 EDN04634.1 - 0.062 12.2 7.4 0.084 11.8 5.1 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 DUF605 PF04652.11 EDN04634.1 - 0.073 12.4 6.2 0.097 12.0 4.3 1.1 1 0 0 1 1 1 0 Vta1 like Nop14 PF04147.7 EDN04634.1 - 0.32 8.8 7.0 0.4 8.5 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 EDN04634.1 - 0.64 9.6 3.0 1 9.0 2.1 1.3 1 0 0 1 1 1 0 FAM176 family Ebola_NP PF05505.7 EDN04634.1 - 2.4 6.1 5.2 3.2 5.6 3.6 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Glyco_transf_34 PF05637.7 EDN04635.1 - 6.8e-32 110.8 0.0 9.5e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family NDUFB10 PF10249.4 EDN04636.1 - 0.0058 16.7 0.0 0.0071 16.4 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Pyr_excise PF03013.9 EDN04636.1 - 0.11 12.2 0.1 0.21 11.3 0.0 1.4 2 0 0 2 2 2 0 Pyrimidine dimer DNA glycosylase BRO1 PF03097.13 EDN04637.1 - 0.0002 20.2 0.0 0.00068 18.4 0.0 1.7 1 1 0 1 1 1 1 BRO1-like domain Bromo_TP PF07524.8 EDN04638.1 - 2.3e-09 36.8 0.0 4.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TAFII55_N PF04658.8 EDN04639.1 - 2.2e-53 180.0 0.0 3.8e-53 179.3 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region F-box-like PF12937.2 EDN04640.1 - 0.021 14.5 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EDN04640.1 - 0.072 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 F-box domain FMO-like PF00743.14 EDN04642.1 - 1.8e-19 69.3 0.0 2.6e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EDN04642.1 - 2.3e-17 63.7 0.2 1.6e-16 61.0 0.1 2.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDN04642.1 - 7.3e-17 61.2 0.0 4.2e-13 48.9 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EDN04642.1 - 6.1e-10 39.3 0.4 0.00024 21.0 0.0 3.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN04642.1 - 3e-05 24.3 0.1 0.0023 18.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN04642.1 - 7.2e-05 21.9 0.8 0.11 11.5 0.1 2.4 2 0 0 2 2 2 2 Thi4 family SnoaL_4 PF13577.1 EDN04642.1 - 0.00068 19.5 0.2 0.12 12.2 0.0 3.3 3 0 0 3 3 3 1 SnoaL-like domain FAD_binding_2 PF00890.19 EDN04642.1 - 0.0026 16.6 0.6 0.11 11.3 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 EDN04642.1 - 0.02 14.9 0.0 0.058 13.4 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SnoaL_2 PF12680.2 EDN04642.1 - 0.029 14.7 0.0 0.42 11.0 0.0 2.6 3 0 0 3 3 3 0 SnoaL-like domain ELFV_dehydrog PF00208.16 EDN04642.1 - 0.1 12.1 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase FAD_binding_3 PF01494.14 EDN04642.1 - 0.14 11.1 0.9 1.7 7.5 0.1 2.3 2 1 1 3 3 3 0 FAD binding domain Ofd1_CTDD PF10637.4 EDN04643.1 - 7.1e-105 349.9 1.2 1.4e-98 329.2 2.2 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EDN04643.1 - 3.5e-16 59.5 0.0 7.5e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PRD PF00874.15 EDN04643.1 - 0.07 13.2 0.3 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 PRD domain DUF966 PF06136.8 EDN04643.1 - 0.24 10.7 7.4 0.48 9.7 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Nop14 PF04147.7 EDN04643.1 - 1.4 6.7 23.5 2.4 5.9 16.3 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EDN04643.1 - 9.6 5.7 25.4 8 5.9 3.5 2.4 2 0 0 2 2 2 0 Nucleoplasmin Trypan_PARP PF05887.6 EDN04644.1 - 0.053 13.3 4.3 0.063 13.1 3.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PROL5-SMR PF15621.1 EDN04644.1 - 4 7.9 9.5 5.7 7.4 6.6 1.3 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Inhibitor_I10 PF12559.3 EDN04647.1 - 0.026 14.7 1.6 3.4 8.0 0.1 2.9 2 0 0 2 2 2 0 Serine endopeptidase inhibitors SDF PF00375.13 EDN04648.1 - 4.8e-88 295.5 30.7 6.1e-88 295.2 21.3 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family CAAD PF14159.1 EDN04648.1 - 0.046 13.3 0.2 0.046 13.3 0.2 2.9 2 1 1 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase UCH PF00443.24 EDN04649.1 - 1.4e-42 145.6 0.1 2.7e-42 144.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 EDN04649.1 - 2.8e-34 118.4 0.0 7.3e-34 117.1 0.0 1.7 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 EDN04649.1 - 8.1e-19 68.1 0.1 1.9e-17 63.6 0.1 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EDN04649.1 - 0.0053 16.9 0.1 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 MATH domain RA PF00788.18 EDN04649.1 - 0.075 13.5 0.0 0.3 11.6 0.0 2.0 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Phosphodiest PF01663.17 EDN04650.1 - 4.5e-88 296.0 0.5 5.8e-88 295.6 0.4 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EDN04650.1 - 0.00071 18.8 0.0 0.14 11.3 0.0 2.3 1 1 1 2 2 2 2 Sulfatase PglZ PF08665.7 EDN04650.1 - 0.011 15.3 0.0 0.2 11.3 0.0 2.4 2 0 0 2 2 2 0 PglZ domain DUF229 PF02995.12 EDN04650.1 - 0.2 10.0 0.0 0.3 9.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Pyr_redox PF00070.22 EDN04651.1 - 3.2e-14 53.0 0.3 3e-11 43.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDN04651.1 - 7e-13 49.0 0.0 1.2e-05 25.5 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDN04651.1 - 9.4e-08 32.1 0.0 0.01 15.7 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDN04651.1 - 9.8e-06 24.7 0.0 0.00039 19.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EDN04651.1 - 1.3e-05 24.2 0.5 0.0083 15.0 0.1 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDN04651.1 - 1.8e-05 23.8 0.7 0.00032 19.7 0.0 2.6 2 1 1 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EDN04651.1 - 0.0007 18.7 0.5 0.11 11.4 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.1 EDN04651.1 - 0.016 15.4 0.0 0.34 11.1 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.1 EDN04651.1 - 0.024 14.6 0.1 5.9 6.9 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EDN04651.1 - 0.048 13.6 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.17 EDN04651.1 - 0.073 11.9 0.0 1.7 7.4 0.0 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EDN04651.1 - 0.082 11.5 0.1 0.55 8.7 0.1 2.2 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.9 EDN04651.1 - 0.12 10.8 0.5 0.49 8.7 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EDN04651.1 - 0.14 11.2 1.2 4.8 6.2 0.1 2.5 3 0 0 3 3 3 0 Thi4 family FAD_binding_2 PF00890.19 EDN04651.1 - 0.2 10.4 1.0 6.7 5.4 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 EDN04651.1 - 0.56 9.2 4.2 0.71 8.8 0.2 2.5 2 1 0 3 3 3 0 FAD dependent oxidoreductase ABC_membrane PF00664.18 EDN04652.1 - 2.4e-70 237.1 30.8 1e-36 126.7 5.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDN04652.1 - 6e-69 230.6 0.1 5e-34 117.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EDN04652.1 - 4.4e-17 62.0 2.9 4.4e-06 26.0 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDN04652.1 - 8e-10 39.1 1.0 0.015 15.3 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EDN04652.1 - 4.1e-09 35.8 0.6 0.0011 18.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EDN04652.1 - 4.9e-09 37.0 0.0 0.0017 19.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EDN04652.1 - 6.7e-08 31.5 0.4 0.00055 18.6 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EDN04652.1 - 1.7e-07 31.4 1.6 0.0018 18.3 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EDN04652.1 - 5.4e-07 29.8 0.5 0.14 12.3 0.1 4.2 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EDN04652.1 - 1.3e-06 27.9 0.1 0.058 12.7 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 EDN04652.1 - 1.8e-06 27.6 1.2 0.15 11.6 0.0 4.3 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 EDN04652.1 - 2.2e-06 26.9 0.0 0.017 14.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 EDN04652.1 - 3.6e-05 23.6 0.1 0.34 10.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 EDN04652.1 - 4.3e-05 23.3 0.2 0.23 11.3 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EDN04652.1 - 5.1e-05 22.8 1.8 0.12 11.7 0.0 3.5 3 1 0 3 3 3 1 AAA-like domain AAA_18 PF13238.1 EDN04652.1 - 6.7e-05 23.1 0.2 0.29 11.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 EDN04652.1 - 0.0002 21.7 0.1 0.65 10.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 EDN04652.1 - 0.00033 20.5 2.9 0.021 14.6 0.1 2.9 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_5 PF07728.9 EDN04652.1 - 0.00041 20.0 0.0 1.9 8.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA PF00004.24 EDN04652.1 - 0.00044 20.4 0.9 5.3 7.2 0.1 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EDN04652.1 - 0.001 18.2 0.1 0.038 13.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.15 EDN04652.1 - 0.0041 16.7 0.2 3.3 7.3 0.0 2.4 2 0 0 2 2 2 2 Adenylylsulphate kinase Mg_chelatase PF01078.16 EDN04652.1 - 0.0046 16.1 0.1 2 7.4 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI G-alpha PF00503.15 EDN04652.1 - 0.016 13.9 0.0 1.2 7.6 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_14 PF13173.1 EDN04652.1 - 0.032 14.1 0.0 14 5.6 0.0 3.5 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.13 EDN04652.1 - 0.039 13.4 0.1 0.42 10.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 EDN04652.1 - 0.044 13.4 0.1 13 5.5 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EDN04652.1 - 0.046 13.2 1.6 1.3 8.4 0.3 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.18 EDN04652.1 - 0.063 13.2 0.1 18 5.3 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.17 EDN04652.1 - 0.065 12.0 0.2 28 3.4 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain AAA_28 PF13521.1 EDN04652.1 - 0.17 11.8 0.0 5.6 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AMP-binding PF00501.23 EDN04653.1 - 9.2e-10 37.4 0.0 1.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EDN04654.1 - 1.9e-59 200.9 0.0 1.7e-36 125.6 0.0 2.5 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EDN04654.1 - 1e-24 86.5 0.7 7.3e-11 42.1 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site RTA1 PF04479.8 EDN04655.1 - 2.3e-14 53.4 7.0 3e-14 53.0 4.9 1.1 1 0 0 1 1 1 1 RTA1 like protein TRI12 PF06609.8 EDN04656.1 - 9.8e-10 37.2 18.3 3e-09 35.6 12.6 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EDN04656.1 - 1.3e-09 37.3 20.0 1.3e-09 37.3 13.9 3.7 3 1 1 5 5 5 3 Major Facilitator Superfamily Pox_A14 PF05767.7 EDN04656.1 - 0.0033 17.3 0.8 0.014 15.3 0.5 2.1 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 MaoC_dehydratas PF01575.14 EDN04657.1 - 8.4e-18 63.9 0.0 1.9e-17 62.7 0.0 1.6 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EDN04657.1 - 5.4e-05 22.9 0.0 0.00029 20.6 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase K_oxygenase PF13434.1 EDN04658.1 - 2.5e-111 371.8 0.0 3e-111 371.6 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EDN04658.1 - 3.7e-10 40.2 0.0 1.9e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN04658.1 - 7.1e-09 35.6 0.0 2.3e-06 27.4 0.0 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDN04658.1 - 4.4e-08 33.2 0.0 5.7e-07 29.6 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN04658.1 - 0.00016 22.0 0.0 0.032 14.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EDN04658.1 - 0.0014 17.5 0.0 0.079 11.8 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EDN04658.1 - 0.065 12.0 0.0 0.83 8.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain AMP-binding PF00501.23 EDN04659.1 - 1e-96 323.8 0.0 1.2e-96 323.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN04659.1 - 3.3e-14 53.5 0.0 1.6e-13 51.3 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Acetyltransf_8 PF13523.1 EDN04660.1 - 1.9e-43 147.9 1.8 2.7e-43 147.4 1.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDN04660.1 - 0.025 14.7 0.1 0.039 14.1 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CBFB_NFYA PF02045.10 EDN04664.1 - 3.5e-25 88.3 5.5 3.5e-25 88.3 3.8 2.5 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 EDN04664.1 - 0.062 12.2 0.0 0.062 12.2 0.0 2.4 2 0 0 2 2 2 0 Hus1-like protein Med15 PF09606.5 EDN04664.1 - 9.8 4.2 68.6 11 4.0 47.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RNase_H PF00075.19 EDN04668.1 - 4.8e-15 56.0 0.0 8e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 EDN04669.1 - 1.6e-35 122.4 0.0 3.1e-35 121.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN04669.1 - 1.3e-14 54.6 0.0 3e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN04669.1 - 8.1e-11 41.5 0.0 1.9e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF1275 PF06912.6 EDN04671.1 - 8.2e-38 129.7 7.9 1.1e-37 129.3 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Acyl-CoA_dh_1 PF00441.19 EDN04672.1 - 1.4e-17 64.1 7.1 9e-12 45.3 0.9 2.3 1 1 1 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDN04672.1 - 1.8e-12 46.5 0.0 4e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EDN04672.1 - 3.6e-12 46.8 1.5 7.6e-12 45.8 0.0 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EDN04672.1 - 2e-06 28.0 5.7 0.00029 21.0 0.2 2.3 1 1 1 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain CPSase_L_chain PF00289.17 EDN04672.1 - 0.015 15.4 0.4 0.036 14.1 0.3 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Glucosaminidase PF01832.15 EDN04672.1 - 0.063 13.3 1.6 0.65 10.1 0.1 2.2 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase MFS_1 PF07690.11 EDN04673.1 - 5.1e-33 114.2 25.6 8.3e-33 113.5 17.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.20 EDN04675.1 - 2e-17 63.6 1.4 2.4e-17 63.3 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN04675.1 - 1.4e-08 34.8 0.0 1.8e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN04675.1 - 2.7e-08 33.6 0.4 3.4e-08 33.3 0.3 1.1 1 0 0 1 1 1 1 KR domain DUF1416 PF07210.7 EDN04675.1 - 0.071 12.7 1.2 0.29 10.7 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1416) ECH PF00378.15 EDN04678.1 - 3.3e-13 49.3 0.2 4.3e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF4276 PF14103.1 EDN04679.1 - 0.0058 16.5 0.5 0.01 15.7 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4276) RRM_1 PF00076.17 EDN04680.1 - 0.032 13.8 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Snf7 PF03357.16 EDN04682.1 - 1.5e-19 69.9 12.7 1.5e-19 69.9 8.8 1.6 1 1 1 2 2 2 1 Snf7 MerR-DNA-bind PF09278.6 EDN04682.1 - 0.11 12.9 12.1 1.7 9.0 0.0 4.3 4 0 0 4 4 4 0 MerR, DNA binding DUF2730 PF10805.3 EDN04682.1 - 0.62 9.8 5.5 7.9 6.2 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) BMFP PF04380.8 EDN04682.1 - 1.1 9.4 8.3 1.3 9.2 0.2 3.8 3 1 1 4 4 4 0 Membrane fusogenic activity CS PF04969.11 EDN04683.1 - 5.1e-06 26.9 0.0 8.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 CS domain zf-CCCH PF00642.19 EDN04686.1 - 4.7e-06 26.1 1.8 4.7e-06 26.1 1.2 2.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PTPS PF01242.14 EDN04686.1 - 0.019 14.6 0.6 1.4 8.6 0.1 2.4 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase FYVE_2 PF02318.11 EDN04686.1 - 0.45 10.4 6.7 8 6.3 0.0 3.2 3 0 0 3 3 3 0 FYVE-type zinc finger Ost4 PF10215.4 EDN04687.1 - 5.7e-19 67.3 0.5 7.5e-19 66.9 0.4 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase KOW PF00467.24 EDN04689.1 - 6.9e-08 31.9 1.8 6.9e-08 31.9 1.2 2.0 2 0 0 2 2 2 1 KOW motif Synaptobrevin PF00957.16 EDN04690.1 - 2.1e-29 100.9 0.0 3.1e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EDN04690.1 - 2.4e-14 52.6 0.0 3.7e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SpoIIAA-like PF11964.3 EDN04690.1 - 0.09 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 SpoIIAA-like DDE_1 PF03184.14 EDN04691.1 - 1.1e-52 178.3 0.0 2e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN04691.1 - 4.7e-11 42.3 0.0 9.4e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN04691.1 - 1.2e-08 34.3 0.1 2.9e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN04691.1 - 4.5e-07 29.7 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC_4 PF14392.1 EDN04691.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Zinc knuckle DEAD PF00270.24 EDN04692.1 - 4.1e-11 42.6 0.0 5.4e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN04692.1 - 0.00031 20.6 0.0 0.001 18.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SH3BP5 PF05276.9 EDN04694.1 - 1.8 7.8 10.9 0.065 12.5 3.5 1.4 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) CPSase_L_D2 PF02786.12 EDN04695.1 - 1.2e-112 374.3 0.1 8.7e-84 280.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EDN04695.1 - 3e-46 156.1 0.0 6.1e-46 155.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EDN04695.1 - 4.4e-45 153.5 0.0 9.9e-45 152.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EDN04695.1 - 2e-42 144.1 0.0 3.9e-42 143.2 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EDN04695.1 - 3.2e-40 136.7 0.0 7.5e-40 135.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EDN04695.1 - 3.2e-35 120.5 0.1 6.4e-18 64.8 0.0 3.8 3 0 0 3 3 3 3 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EDN04695.1 - 3.4e-35 121.4 0.3 2.3e-21 76.3 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain OTCace PF00185.19 EDN04695.1 - 2.2e-33 115.3 0.0 5.1e-33 114.1 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.17 EDN04695.1 - 7.5e-23 80.2 0.0 8e-22 76.9 0.0 2.7 2 0 0 2 2 2 1 MGS-like domain ATPgrasp_Ter PF15632.1 EDN04695.1 - 1.3e-20 73.3 0.1 2.3e-09 36.4 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EDN04695.1 - 2.9e-15 56.1 0.1 2.1e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EDN04695.1 - 3.1e-14 52.7 0.0 4.3e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EDN04695.1 - 1.5e-06 27.8 0.1 8.5e-05 22.0 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 EDN04695.1 - 4.4e-05 23.3 0.1 0.28 11.0 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 EDN04695.1 - 8.4e-05 22.1 0.0 0.075 12.5 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain DJ-1_PfpI PF01965.19 EDN04695.1 - 0.045 13.2 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family Ish1 PF10281.4 EDN04695.1 - 0.21 11.6 0.0 4.2 7.5 0.0 2.8 3 0 0 3 3 2 0 Putative stress-responsive nuclear envelope protein MRI PF15325.1 EDN04696.1 - 0.45 11.4 2.8 0.6 11.1 1.9 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection Sec62 PF03839.11 EDN04696.1 - 1 8.7 7.5 1.2 8.5 5.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 SGL PF08450.7 EDN04697.1 - 2e-20 73.2 0.1 2.9e-20 72.7 0.1 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region ABC_tran PF00005.22 EDN04698.1 - 1.3e-24 87.0 0.0 6.3e-11 42.7 0.0 3.1 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EDN04698.1 - 6.3e-09 36.2 0.1 0.001 19.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EDN04698.1 - 5.3e-05 23.0 0.0 0.059 13.2 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EDN04698.1 - 0.042 13.3 0.4 0.1 12.1 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.1 EDN04698.1 - 0.095 11.1 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EDN04698.1 - 0.11 12.5 0.2 2.1 8.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 EDN04698.1 - 0.16 12.4 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 EDN04698.1 - 5.1 7.3 5.3 1.4 9.1 1.1 1.9 2 0 0 2 2 2 0 AAA domain Vps51 PF08700.6 EDN04699.1 - 3.6e-18 65.1 2.8 1.1e-17 63.5 2.0 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.1 EDN04699.1 - 0.0076 15.9 0.6 1.1 8.9 0.1 2.5 2 0 0 2 2 2 2 Exocyst complex component Sec5 COG2 PF06148.6 EDN04699.1 - 0.013 15.4 0.7 0.035 13.9 0.1 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3829 PF12889.2 EDN04699.1 - 0.13 11.4 2.7 6 5.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DUF342 PF03961.8 EDN04699.1 - 0.23 9.8 3.0 0.1 11.0 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) TPR_MLP1_2 PF07926.7 EDN04699.1 - 2.9 7.6 10.1 0.4 10.4 3.2 2.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 EDN04699.1 - 7.4 6.3 8.6 1.2 8.9 1.5 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MAS20 PF02064.10 EDN04700.1 - 6e-18 64.9 0.1 1.4e-17 63.6 0.1 1.5 1 1 0 1 1 1 1 MAS20 protein import receptor Glyco_hydro_72 PF03198.9 EDN04701.1 - 3.3e-116 387.6 0.0 4.3e-116 387.2 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EDN04701.1 - 0.0067 15.3 0.0 0.03 13.2 0.0 1.8 1 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EDN04701.1 - 0.15 11.2 0.1 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) F-box-like PF12937.2 EDN04702.1 - 5.3e-12 45.2 0.4 1.1e-11 44.2 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN04702.1 - 1e-11 44.1 0.2 2.1e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain Apc4_WD40 PF12894.2 EDN04702.1 - 0.087 12.3 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Mre11_DNA_bind PF04152.9 EDN04703.1 - 3.6e-59 199.5 1.2 7.5e-59 198.5 0.8 1.6 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EDN04703.1 - 4.3e-24 85.0 1.6 6.2e-24 84.4 1.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mito_fiss_reg PF05308.6 EDN04703.1 - 0.028 13.7 0.4 0.028 13.7 0.3 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator Metallophos_3 PF14582.1 EDN04703.1 - 0.033 13.3 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily CAP_N PF01213.14 EDN04703.1 - 5.2 6.2 12.8 0.098 11.9 0.9 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Aldedh PF00171.17 EDN04705.1 - 2e-175 583.6 2.7 2.9e-175 583.0 1.9 1.3 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Metallophos PF00149.23 EDN04706.1 - 3.5e-28 98.3 0.0 1.2e-22 80.2 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Ctr PF04145.10 EDN04707.1 - 5.4e-37 127.0 5.0 6.8e-37 126.7 3.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF4131 PF13567.1 EDN04707.1 - 0.024 14.0 3.0 0.31 10.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1673 PF07895.6 EDN04707.1 - 0.059 12.8 1.7 0.22 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Transgly_assoc PF04226.8 EDN04707.1 - 0.41 10.7 5.7 5.5 7.1 0.4 2.6 2 1 0 2 2 2 0 Transglycosylase associated protein Fork_head_N PF08430.7 EDN04707.1 - 2.1 8.7 16.4 3 8.2 11.4 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region Sensor PF13796.1 EDN04707.1 - 4.8 6.7 8.1 2.6 7.6 0.1 2.3 2 1 0 2 2 2 0 Putative sensor CEP44 PF15007.1 EDN04708.1 - 0.056 13.1 0.2 0.063 12.9 0.2 1.1 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 RVT_1 PF00078.22 EDN04709.1 - 1.5e-34 119.2 0.0 2.3e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN04709.1 - 4.5e-14 52.9 0.0 1.1e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN04709.1 - 2.1e-13 49.9 0.0 4.4e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Herpes_LMP1 PF05297.6 EDN04711.1 - 1.1 8.1 3.4 1.8 7.4 2.3 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Aminotran_3 PF00202.16 EDN04713.1 - 2.1e-101 339.1 0.0 2.5e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EDN04713.1 - 0.079 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Spt4 PF06093.8 EDN04714.1 - 4.6e-32 109.7 0.2 7.5e-32 109.0 0.1 1.3 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger ETRAMP PF09716.5 EDN04714.1 - 0.02 14.8 0.9 0.032 14.1 0.6 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Coronavirus_5 PF05528.6 EDN04714.1 - 0.051 13.3 0.1 0.094 12.5 0.1 1.5 1 0 0 1 1 1 0 Coronavirus gene 5 protein Metallophos PF00149.23 EDN04715.1 - 1.3e-39 135.6 0.1 1.9e-39 135.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EDN04715.1 - 1.3e-28 98.8 0.1 2.8e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EDN04715.1 - 5.1e-18 64.4 4.0 3.4e-14 52.2 0.4 2.8 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 EDN04715.1 - 6.9e-09 34.9 5.1 0.00017 21.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDN04715.1 - 5e-08 32.2 5.1 0.011 15.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN04715.1 - 8.9e-05 23.0 3.1 0.17 12.6 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDN04715.1 - 0.00032 20.9 0.6 0.69 10.2 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDN04715.1 - 0.00036 20.3 0.2 0.004 16.9 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDN04715.1 - 0.0033 17.4 0.6 4.5 7.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN04715.1 - 0.012 16.2 1.6 5.4 7.9 0.1 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDN04715.1 - 0.026 14.9 1.0 7.6 7.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF89 PF01937.14 EDN04716.1 - 8.7e-132 439.2 0.0 1.1e-131 438.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Cut12 PF11500.3 EDN04717.1 - 4.2e-47 159.6 16.3 4.2e-47 159.6 11.3 3.3 3 1 0 3 3 3 1 Spindle pole body formation-associated protein HGTP_anticodon2 PF12745.2 EDN04718.1 - 8.3e-80 267.8 1.9 8.3e-80 267.8 1.3 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EDN04718.1 - 6.2e-32 110.7 7.9 1.7e-11 43.7 0.0 5.4 5 1 1 6 6 6 4 Protein kinase domain Pkinase_Tyr PF07714.12 EDN04718.1 - 1.6e-14 53.6 0.0 2.8e-06 26.5 0.0 3.9 3 1 1 4 4 4 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 EDN04718.1 - 4.6e-14 52.1 0.2 2.4e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase RWD PF05773.17 EDN04718.1 - 1.1e-13 51.0 0.0 6.4e-13 48.5 0.0 2.4 2 0 0 2 2 2 1 RWD domain HGTP_anticodon PF03129.15 EDN04718.1 - 1.6e-06 27.9 0.1 4.5e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain UPF0075 PF03702.9 EDN04718.1 - 0.23 10.3 0.0 0.43 9.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) RRM_1 PF00076.17 EDN04719.1 - 1.7e-08 33.9 0.0 3.4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN04719.1 - 1.1e-06 28.3 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN04719.1 - 9.8e-05 22.2 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDN04719.1 - 0.0023 17.6 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TGS PF02824.16 EDN04720.1 - 5.7e-21 74.1 0.5 1.1e-20 73.1 0.1 1.7 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.18 EDN04720.1 - 5.9e-19 68.1 0.1 1.1e-18 67.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDN04720.1 - 4.2e-13 48.8 0.0 6.9e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EDN04720.1 - 4.3e-05 23.4 0.4 0.13 12.0 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EDN04720.1 - 0.0012 19.3 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 EDN04720.1 - 0.049 12.4 0.1 0.11 11.2 0.1 1.6 1 0 0 1 1 1 0 ArgK protein AIG1 PF04548.11 EDN04720.1 - 0.063 12.3 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MCM PF00493.18 EDN04720.1 - 0.078 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family DnaJ PF00226.26 EDN04721.1 - 8.9e-27 92.6 2.8 1.4e-26 92.0 1.9 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EDN04721.1 - 8e-21 73.7 1.7 2e-19 69.2 0.1 2.5 2 1 0 2 2 2 2 DnaJ C terminal domain PIG-X PF08320.7 EDN04722.1 - 6.8e-79 263.9 0.0 8.8e-79 263.5 0.0 1.1 1 0 0 1 1 1 1 PIG-X / PBN1 RFX_DNA_binding PF02257.10 EDN04723.1 - 9e-24 83.4 0.2 2.3e-23 82.1 0.1 1.7 1 0 0 1 1 1 1 RFX DNA-binding domain TB2_DP1_HVA22 PF03134.14 EDN04724.1 - 8.8e-31 105.5 7.8 1.3e-30 105.0 5.4 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF1649 PF07855.7 EDN04725.1 - 7.9e-71 236.9 0.0 9.1e-71 236.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Peroxin-3 PF04882.7 EDN04726.1 - 1.6e-44 152.3 0.1 1.9e-44 152.1 0.1 1.0 1 0 0 1 1 1 1 Peroxin-3 Na_H_Exchanger PF00999.16 EDN04727.1 - 6.5e-70 235.5 42.1 9.8e-70 234.9 29.2 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Peroxin-3 PF04882.7 EDN04727.1 - 2.6e-45 154.9 1.0 3.6e-45 154.4 0.7 1.2 1 0 0 1 1 1 1 Peroxin-3 MFS_1 PF07690.11 EDN04729.1 - 2.6e-23 82.2 12.3 3.5e-23 81.8 8.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ThiF PF00899.16 EDN04731.1 - 1.7e-16 60.2 0.1 2.7e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 ThiF family Ytp1 PF10355.4 EDN04732.1 - 1.5e-86 290.0 12.8 1.5e-86 290.0 8.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EDN04732.1 - 4.3e-33 113.0 3.7 4.3e-33 113.0 2.6 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Ion_trans_2 PF07885.11 EDN04732.1 - 0.11 12.2 0.2 0.11 12.2 0.1 4.2 4 0 0 4 4 4 0 Ion channel BLOC1_2 PF10046.4 EDN04733.1 - 0.001 19.1 1.0 0.003 17.6 0.4 1.9 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec8_exocyst PF04048.9 EDN04733.1 - 0.012 15.2 1.8 0.013 15.0 0.5 1.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain IncA PF04156.9 EDN04733.1 - 0.015 14.9 6.8 0.052 13.1 4.3 2.0 2 0 0 2 2 2 0 IncA protein Nup88 PF10168.4 EDN04733.1 - 0.022 12.6 3.3 0.029 12.2 2.3 1.1 1 0 0 1 1 1 0 Nuclear pore component Tweety PF04906.8 EDN04733.1 - 0.047 12.1 1.6 0.12 10.8 0.6 1.7 2 0 0 2 2 2 0 Tweety Cytochrom_C PF00034.16 EDN04733.1 - 0.047 14.5 0.5 0.31 11.8 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c Fib_alpha PF08702.5 EDN04733.1 - 0.17 12.0 5.4 2.8 8.0 1.5 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4446 PF14584.1 EDN04733.1 - 1.6 8.5 4.6 60 3.4 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DivIVA PF05103.8 EDN04733.1 - 2.7 8.0 9.9 13 5.8 4.8 2.5 2 0 0 2 2 2 0 DivIVA protein COG2 PF06148.6 EDN04733.1 - 6.2 6.6 8.4 1.3 8.8 3.2 1.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4337 PF14235.1 EDN04733.1 - 6.7 6.5 6.8 12 5.7 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Cyclin_N PF00134.18 EDN04734.1 - 0.0042 16.6 0.0 0.11 12.0 0.0 2.7 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EDN04734.1 - 0.011 15.5 0.0 0.44 10.4 0.0 2.6 2 1 0 2 2 2 0 Transcription factor TFIIB repeat Autophagy_act_C PF03987.10 EDN04735.1 - 2e-23 82.3 0.2 7e-23 80.5 0.1 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EDN04735.1 - 1.3e-14 52.9 0.5 2.2e-14 52.2 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Glycos_transf_2 PF00535.21 EDN04736.1 - 1.1e-21 77.3 0.0 9.8e-19 67.6 0.0 2.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EDN04736.1 - 1.9e-07 31.1 0.1 0.019 14.8 0.1 3.7 2 1 1 3 3 3 2 Glycosyltransferase like family 2 DDE_1 PF03184.14 EDN04737.1 - 5.7e-05 22.3 0.0 0.00034 19.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN04737.1 - 0.011 15.5 0.0 0.037 13.8 0.0 2.0 1 1 0 1 1 1 0 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN04737.1 - 0.023 14.2 0.0 0.088 12.3 0.0 1.9 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_8 PF02954.14 EDN04737.1 - 0.026 14.0 0.1 0.54 9.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HTH_Tnp_IS630 PF01710.11 EDN04737.1 - 0.12 12.0 0.0 2.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Transposase DUF3818 PF12825.2 EDN04738.1 - 0.15 10.7 1.7 0.16 10.5 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) YebO PF13974.1 EDN04738.1 - 0.91 9.3 5.5 0.66 9.7 2.6 1.6 1 1 1 2 2 2 0 YebO-like protein RVT_1 PF00078.22 EDN04740.1 - 1.4e-21 76.8 0.1 3e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN04740.1 - 1.1e-17 64.2 0.4 3.5e-17 62.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EDN04740.1 - 3.6e-13 48.9 1.0 8.6e-13 47.7 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EDN04740.1 - 0.00016 21.0 0.1 0.00045 19.5 0.0 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Tudor-knot PF11717.3 EDN04740.1 - 0.0032 17.1 0.4 0.029 14.0 0.0 2.6 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain RVP PF00077.15 EDN04740.1 - 0.028 14.3 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EDN04740.1 - 0.071 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDN04740.1 - 0.15 12.5 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease APH PF01636.18 EDN04741.1 - 1.3e-07 31.5 0.0 2.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN04741.1 - 0.0002 21.0 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EDN04741.1 - 0.042 12.9 0.0 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase DDE_1 PF03184.14 EDN04742.1 - 5.2e-36 123.8 0.0 1.1e-35 122.7 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN04742.1 - 1.8e-11 43.7 0.0 3.4e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN04742.1 - 1.4e-10 40.5 0.2 2.6e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN04742.1 - 0.0004 20.1 0.0 0.00079 19.1 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 EDN04742.1 - 0.036 14.0 0.1 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain NUDIX PF00293.23 EDN04743.1 - 0.00065 19.3 0.1 0.0013 18.4 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 EDN04744.1 - 3e-17 62.5 0.0 4.7e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF3433 PF11915.3 EDN04745.1 - 3.6e-19 68.6 1.3 3.6e-19 68.6 0.9 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3433) DUF588 PF04535.7 EDN04745.1 - 0.0044 16.5 0.9 0.011 15.2 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF588) HAD_2 PF13419.1 EDN04746.1 - 2.9e-14 53.6 0.0 3.7e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NIF PF03031.13 EDN04746.1 - 1.8e-05 24.4 0.0 0.0025 17.5 0.0 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Hydrolase_like PF13242.1 EDN04746.1 - 4.1e-05 23.2 0.0 7.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDN04746.1 - 0.00035 21.0 0.0 0.0023 18.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase VitK2_biosynth PF02621.9 EDN04746.1 - 0.076 12.2 0.0 0.31 10.1 0.0 1.8 1 1 0 2 2 2 0 Menaquinone biosynthesis Init_tRNA_PT PF04179.7 EDN04747.1 - 4.1e-170 566.5 0.0 6.4e-170 565.8 0.0 1.3 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase BTB PF00651.26 EDN04748.1 - 0.0088 16.0 0.1 0.021 14.7 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain RVT_1 PF00078.22 EDN04749.1 - 2.4e-08 33.6 0.0 4.5e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EDN04750.1 - 1.1e-31 109.9 0.0 2.2e-31 108.8 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN04750.1 - 5e-15 55.1 0.0 2.5e-14 52.9 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 EDN04750.1 - 0.00047 19.9 4.1 0.00047 19.9 2.9 2.3 2 0 0 2 2 2 1 Zinc knuckle Exo_endo_phos PF03372.18 EDN04750.1 - 0.00066 19.6 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC_4 PF14392.1 EDN04750.1 - 0.76 9.5 12.8 2.7 7.7 1.0 2.6 1 1 1 2 2 2 0 Zinc knuckle CotJB PF12652.2 EDN04751.1 - 0.66 10.0 4.7 11 6.1 0.0 3.3 2 1 0 3 3 3 0 CotJB protein FlxA PF14282.1 EDN04751.1 - 3 7.8 11.4 0.32 10.9 2.3 2.4 2 0 0 2 2 2 0 FlxA-like protein Retrotrans_gag PF03732.12 EDN04751.1 - 3.8 7.6 14.1 0.86 9.7 1.3 3.3 2 1 1 3 3 3 0 Retrotransposon gag protein RVT_thumb PF06817.9 EDN04752.1 - 0.044 13.3 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase thumb domain RVP_2 PF08284.6 EDN04752.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Transp_cyt_pur PF02133.10 EDN04756.1 - 9.2e-75 251.8 18.2 1.1e-74 251.5 6.7 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Urb2 PF10441.4 EDN04757.1 - 5.2e-60 202.8 0.6 1.8e-58 197.7 0.0 2.7 2 0 0 2 2 2 1 Urb2/Npa2 family TMV_coat PF00721.16 EDN04757.1 - 0.064 13.1 0.6 0.32 10.8 0.0 2.5 2 0 0 2 2 2 0 Virus coat protein (TMV like) DUF543 PF04418.7 EDN04758.1 - 6.2e-25 86.9 0.1 7e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Halogen_Hydrol PF10112.4 EDN04758.1 - 0.14 11.5 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Copper-fist PF00649.13 EDN04759.1 - 2e-19 68.4 0.3 7.1e-19 66.7 0.2 2.0 1 0 0 1 1 1 1 Copper fist DNA binding domain Exo_endo_phos_2 PF14529.1 EDN04762.1 - 3.1e-14 52.6 0.0 6.9e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DASH_Dam1 PF08653.5 EDN04762.1 - 0.067 12.9 0.1 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Dam1 AvrE PF11725.3 EDN04762.1 - 0.088 9.8 3.4 0.12 9.3 2.3 1.1 1 0 0 1 1 1 0 Pathogenicity factor Rep-A_N PF04057.7 EDN04763.1 - 0.16 11.7 0.1 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain Aldo_ket_red PF00248.16 EDN04764.1 - 3.8e-19 68.5 0.0 4.8e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SLAC1 PF03595.12 EDN04765.1 - 1.3e-72 244.2 36.8 5.6e-47 159.9 12.6 2.0 1 1 1 2 2 2 2 Voltage-dependent anion channel EamA PF00892.15 EDN04767.1 - 1e-08 35.2 27.1 6.3e-07 29.4 1.4 3.3 3 0 0 3 3 3 3 EamA-like transporter family PgaD PF13994.1 EDN04767.1 - 6.5e-06 25.6 1.4 5.9e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 PgaD-like protein EmrE PF13536.1 EDN04767.1 - 0.00015 21.9 17.5 0.00032 20.8 0.6 2.9 2 1 1 3 3 3 2 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EDN04767.1 - 0.0053 15.9 1.2 0.0056 15.8 0.0 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter DUF914 PF06027.7 EDN04767.1 - 0.01 14.6 0.4 0.02 13.7 0.3 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) DUF1469 PF07332.6 EDN04767.1 - 0.015 15.0 0.1 0.015 15.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) TPT PF03151.11 EDN04767.1 - 0.4 10.3 15.6 0.47 10.0 2.7 3.1 3 1 0 3 3 3 0 Triose-phosphate Transporter family PRRSV_Env PF02340.10 EDN04767.1 - 1.2 8.2 9.7 0.34 10.0 1.4 2.6 2 1 1 3 3 3 0 PRRSV putative envelope protein DUF202 PF02656.10 EDN04767.1 - 2.4 8.4 15.8 0.2 11.8 1.5 3.8 3 2 0 3 3 3 0 Domain of unknown function (DUF202) Actin PF00022.14 EDN04768.1 - 1.6e-117 392.3 0.0 1.9e-117 392.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EDN04768.1 - 0.042 12.4 0.0 0.24 9.9 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein DUF3425 PF11905.3 EDN04769.1 - 4.1e-38 130.3 3.7 7.5e-38 129.4 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EDN04769.1 - 0.014 15.3 8.3 0.036 14.0 5.7 1.7 1 0 0 1 1 1 0 bZIP transcription factor Methyltransf_31 PF13847.1 EDN04770.1 - 4.7e-12 45.7 0.0 6.4e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN04770.1 - 2.7e-10 40.2 0.1 6e-10 39.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN04770.1 - 5.5e-08 33.1 0.1 5.1e-07 30.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN04770.1 - 4.6e-07 30.2 0.0 1.6e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN04770.1 - 2.6e-05 24.7 0.0 5.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN04770.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain SelP_N PF04592.9 EDN04770.1 - 0.17 11.2 6.1 0.25 10.6 4.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region GTP_cyclohydro2 PF00925.15 EDN04771.1 - 2.7e-32 111.3 0.1 3.1e-32 111.1 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II GTP_cyclohydro2 PF00925.15 EDN04772.1 - 0.0059 15.8 0.0 0.0082 15.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF1325 PF07039.6 EDN04773.1 - 7.5e-31 106.4 0.0 1.1e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Pap_E4 PF02711.9 EDN04773.1 - 0.078 13.7 1.3 0.13 13.0 0.9 1.3 1 0 0 1 1 1 0 E4 protein PMI_typeI PF01238.16 EDN04774.1 - 1.1e-143 478.7 0.0 1.3e-143 478.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Abhydrolase_3 PF07859.8 EDN04775.1 - 4.2e-22 78.7 0.0 6.1e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EDN04775.1 - 1.7e-16 59.8 0.0 2.2e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DUF2974 PF11187.3 EDN04775.1 - 0.014 14.8 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EDN04775.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Coatomer_E PF04733.9 EDN04776.1 - 9.2e-63 212.1 1.9 1.1e-62 211.9 1.3 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EDN04776.1 - 2.8e-06 27.5 11.6 0.0017 18.6 1.0 4.2 3 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDN04776.1 - 1e-05 26.0 3.5 0.084 13.5 0.0 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EDN04776.1 - 1.8e-05 24.7 0.0 0.13 12.3 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EDN04776.1 - 4.3e-05 23.3 0.7 0.13 12.2 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN04776.1 - 0.00023 21.5 8.3 0.039 14.5 0.0 4.7 4 1 2 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDN04776.1 - 0.00065 19.1 0.1 0.27 10.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDN04776.1 - 0.00096 19.4 0.0 1.4 9.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDN04776.1 - 0.0035 17.1 6.0 0.12 12.3 0.0 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDN04776.1 - 0.0057 16.2 0.1 2 8.1 0.0 3.6 4 1 0 4 4 4 1 TPR repeat TPR_20 PF14561.1 EDN04776.1 - 0.55 10.3 6.4 0.74 9.9 0.1 3.7 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EDN04776.1 - 0.69 10.5 16.0 2.7 8.6 0.1 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat AA_permease PF00324.16 EDN04778.1 - 8e-119 397.0 34.6 1e-118 396.7 24.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDN04778.1 - 2.4e-34 118.6 38.3 3.2e-34 118.2 26.6 1.0 1 0 0 1 1 1 1 Amino acid permease FTA4 PF13093.1 EDN04780.1 - 1.5e-64 217.3 6.7 9.4e-38 129.7 0.0 2.0 1 1 1 2 2 2 2 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 HAD_2 PF13419.1 EDN04781.1 - 1.3e-13 51.5 0.0 2.7e-13 50.5 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN04781.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Ribosomal_L18p PF00861.17 EDN04782.1 - 2.2e-43 147.2 0.3 2.2e-43 147.2 0.2 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EDN04782.1 - 2.8e-33 114.3 5.8 2.8e-33 114.3 4.0 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region LRR_6 PF13516.1 EDN04783.1 - 0.013 15.4 6.0 68 4.0 0.2 6.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.2 EDN04783.1 - 0.028 14.0 5.4 0.13 11.9 0.2 4.3 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF3135 PF11333.3 EDN04783.1 - 0.13 12.4 1.3 0.65 10.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) ABC_membrane_2 PF06472.10 EDN04784.1 - 5.1e-108 360.4 0.9 8e-108 359.8 0.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EDN04784.1 - 9e-09 35.7 0.0 1.6e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EDN04784.1 - 9.8e-05 22.4 0.0 0.0003 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EDN04784.1 - 0.019 15.3 0.0 0.036 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EDN04784.1 - 0.042 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 EDN04784.1 - 0.061 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EDN04784.1 - 0.08 12.9 0.5 0.25 11.2 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain Phosphorylase PF00343.15 EDN04785.1 - 8.5e-295 979.2 0.3 1.2e-294 978.7 0.2 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase Rsa3 PF14615.1 EDN04785.1 - 0.074 12.3 0.0 0.69 9.2 0.0 2.5 2 0 0 2 2 2 0 Ribosome-assembly protein 3 4HBT PF03061.17 EDN04786.1 - 2.6e-08 33.8 0.1 4.2e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EDN04786.1 - 0.00064 19.5 0.2 0.00087 19.1 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF2808 PF10989.3 EDN04786.1 - 0.012 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Glyco_hydro_47 PF01532.15 EDN04787.1 - 4.9e-132 440.8 0.2 5.9e-132 440.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 EDN04787.1 - 0.0052 16.1 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Avl9 PF09794.4 EDN04788.1 - 1.1e-108 363.0 0.0 1.6e-57 194.7 0.0 2.1 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.5 EDN04788.1 - 4.3e-05 23.1 0.0 8.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 EDN04788.1 - 0.0025 17.8 0.7 0.01 15.8 0.0 2.3 3 0 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2347 PF09804.4 EDN04788.1 - 0.014 14.6 0.5 2 7.6 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2347) Pkinase PF00069.20 EDN04789.1 - 1.8e-72 243.6 0.0 2.2e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN04789.1 - 1.3e-31 109.6 0.0 1.6e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDN04789.1 - 3.4e-05 22.9 0.0 0.00012 21.2 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDN04789.1 - 0.00029 19.8 0.0 0.028 13.4 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EDN04789.1 - 0.00043 20.0 0.1 0.0019 17.9 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDN04789.1 - 0.048 12.9 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EDN04790.1 - 3.7e-17 62.8 0.2 6.8e-17 61.9 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EDN04790.1 - 2.1e-05 23.3 0.3 0.0056 15.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EDN04790.1 - 4.1e-05 23.2 0.0 6.9e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EDN04790.1 - 0.00073 18.5 0.0 0.0013 17.7 0.0 1.5 1 1 0 1 1 1 1 Fructosamine kinase Pkinase PF00069.20 EDN04790.1 - 0.019 14.1 0.1 4.4 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain UPF0370 PF13980.1 EDN04790.1 - 0.064 13.0 1.7 0.55 10.0 0.0 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0370) WD40 PF00400.27 EDN04791.1 - 1.1e-76 250.1 17.2 9.1e-12 44.3 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EDN04791.1 - 5.6e-11 41.2 1.8 0.00068 17.8 0.0 4.0 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDN04791.1 - 0.0011 17.7 0.0 1.6 7.4 0.0 3.1 2 2 1 3 3 3 2 Nup133 N terminal like G-alpha PF00503.15 EDN04792.1 - 1.7e-25 89.5 0.0 1.9e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit zf-met PF12874.2 EDN04793.1 - 1.9e-24 85.0 25.6 2.5e-09 37.0 0.1 5.7 6 0 0 6 6 5 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDN04793.1 - 3.6e-23 81.0 19.4 8.3e-09 35.3 0.1 5.5 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EDN04793.1 - 7.2e-16 57.4 29.9 0.0056 16.9 0.2 6.7 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EDN04793.1 - 5.4e-12 45.6 22.9 0.0061 16.6 0.7 6.0 2 2 4 6 6 6 4 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EDN04793.1 - 9.8e-12 44.3 23.7 0.09 13.1 0.3 7.1 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EDN04793.1 - 5.2e-05 22.7 16.1 0.15 11.7 0.3 5.7 5 0 0 5 5 5 2 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 EDN04793.1 - 0.0001 22.4 21.2 1.6 9.1 0.1 6.5 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EDN04793.1 - 0.00054 19.7 25.1 0.31 10.9 0.0 5.9 6 0 0 6 6 5 3 C2H2-type zinc finger zf-DBF PF07535.7 EDN04793.1 - 0.0019 17.8 17.6 0.32 10.7 0.0 5.4 4 2 2 6 6 6 1 DBF zinc finger Rad50_zn_hook PF04423.9 EDN04793.1 - 0.3 10.5 3.4 7.5 6.1 0.0 3.4 4 0 0 4 4 4 0 Rad50 zinc hook motif HNH_5 PF14279.1 EDN04793.1 - 0.88 9.6 6.1 3.3 7.7 0.6 2.8 2 1 0 2 2 2 0 HNH endonuclease zf-BED PF02892.10 EDN04793.1 - 1.1 9.0 18.3 3.8 7.3 0.1 5.1 2 1 3 5 5 5 0 BED zinc finger C1_4 PF07975.7 EDN04793.1 - 1.3 9.0 21.4 3.7 7.6 1.1 4.3 2 1 1 4 4 4 0 TFIIH C1-like domain LIM PF00412.17 EDN04793.1 - 2.4 8.2 12.6 2.1 8.4 0.1 3.0 2 1 0 2 2 2 0 LIM domain zf-Sec23_Sec24 PF04810.10 EDN04793.1 - 3.5 7.2 8.8 2.7 7.6 0.1 3.4 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger zf-DNA_Pol PF08996.5 EDN04793.1 - 4 6.7 15.0 1.1 8.5 0.5 3.1 2 1 1 3 3 3 0 DNA Polymerase alpha zinc finger Cullin PF00888.17 EDN04794.1 - 3.4e-170 567.4 5.5 3.3e-89 300.0 1.4 2.2 1 1 1 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 EDN04794.1 - 6.7e-28 96.3 5.2 7.5e-28 96.1 2.1 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain UCH_1 PF13423.1 EDN04794.1 - 0.026 13.9 0.1 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Abi_C PF14355.1 EDN04794.1 - 0.077 12.9 0.0 0.3 11.0 0.0 2.0 1 0 0 1 1 1 0 Abortive infection C-terminus CBM_25 PF03423.8 EDN04795.1 - 0.012 15.6 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) MARVEL PF01284.18 EDN04796.1 - 0.001 18.8 1.7 0.0017 18.1 1.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain Mit_KHE1 PF10173.4 EDN04797.1 - 3.8e-65 219.2 1.1 5.9e-65 218.6 0.8 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related End3 PF12761.2 EDN04798.1 - 4.7e-76 254.8 0.1 6.2e-76 254.4 0.1 1.1 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EDN04798.1 - 2e-37 127.0 0.2 4.6e-37 125.9 0.1 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EDN04798.1 - 9.3e-08 30.8 0.3 2.5e-07 29.5 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EDN04798.1 - 2.1e-05 24.5 0.0 0.00011 22.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EDN04798.1 - 2.8e-05 23.6 0.0 6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EDN04798.1 - 3.7e-05 23.2 0.1 0.00018 21.1 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EDN04798.1 - 0.00061 19.0 0.6 0.0022 17.2 0.2 2.1 2 0 0 2 2 2 1 EF hand TPR_MLP1_2 PF07926.7 EDN04798.1 - 0.0016 18.2 2.5 0.048 13.4 0.7 2.4 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF4208 PF13907.1 EDN04798.1 - 0.19 11.9 1.1 0.58 10.4 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) DUF4407 PF14362.1 EDN04798.1 - 0.21 10.5 3.5 0.34 9.8 2.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Rabaptin PF03528.10 EDN04798.1 - 0.67 9.8 9.8 2.3 8.1 5.6 2.5 1 1 0 1 1 1 0 Rabaptin Spc24 PF08286.6 EDN04798.1 - 0.74 9.5 3.5 14 5.3 0.1 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Spc7 PF08317.6 EDN04798.1 - 0.87 8.1 6.1 1.2 7.7 2.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 EDN04798.1 - 1.1 8.8 6.0 26 4.3 0.0 2.2 2 0 0 2 2 2 0 IncA protein DUF947 PF06102.7 EDN04798.1 - 1.1 9.0 4.9 3.1 7.5 3.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF947) SNF2_N PF00176.18 EDN04799.1 - 6.1e-67 225.5 0.0 1.1e-66 224.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN04799.1 - 4.6e-16 58.4 0.1 3.7e-15 55.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DSPc PF00782.15 EDN04801.1 - 4.4e-10 39.2 0.0 2.5e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EDN04801.1 - 0.065 12.0 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase zf-C2H2_4 PF13894.1 EDN04803.1 - 3.1e-07 30.2 12.6 0.01 16.0 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN04803.1 - 1.2e-06 28.4 16.0 0.0029 17.8 0.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type FSIP1 PF15554.1 EDN04803.1 - 0.024 13.4 2.1 0.033 13.0 1.4 1.2 1 0 0 1 1 1 0 FSIP1 family Med4 PF10018.4 EDN04803.1 - 0.033 13.5 0.7 0.07 12.5 0.5 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 IncA PF04156.9 EDN04803.1 - 0.035 13.6 0.6 0.078 12.5 0.4 1.5 2 0 0 2 2 2 0 IncA protein ATG16 PF08614.6 EDN04803.1 - 0.037 13.8 0.6 0.056 13.2 0.4 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-H2C2_2 PF13465.1 EDN04803.1 - 0.052 13.8 16.2 0.4 11.0 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger double domain Spindle_Spc25 PF08234.7 EDN04805.1 - 0.024 14.6 0.0 0.025 14.5 0.0 1.0 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 A_deaminase PF00962.17 EDN04806.1 - 2.7e-30 105.4 0.0 3.3e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF1771 PF08590.5 EDN04807.1 - 2.6e-21 75.3 9.4 2.6e-21 75.3 6.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EDN04807.1 - 2e-16 59.9 0.3 4.7e-16 58.7 0.2 1.7 1 0 0 1 1 1 1 Smr domain Uds1 PF15456.1 EDN04807.1 - 0.38 10.7 2.5 8.3 6.4 0.9 2.5 3 0 0 3 3 3 0 Up-regulated During Septation Connexin43 PF03508.8 EDN04807.1 - 0.41 9.9 2.7 0.44 9.8 0.3 2.2 2 0 0 2 2 2 0 Gap junction alpha-1 protein (Cx43) Beta_elim_lyase PF01212.16 EDN04808.1 - 1.8e-77 260.3 0.0 2.3e-77 260.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EDN04808.1 - 7e-05 21.2 0.3 0.00012 20.5 0.0 1.4 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EDN04808.1 - 0.0099 14.9 0.1 0.12 11.3 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family polyprenyl_synt PF00348.12 EDN04809.1 - 6.1e-59 198.9 0.0 7.7e-59 198.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Sugar_tr PF00083.19 EDN04810.1 - 1.6e-81 274.1 18.7 2e-81 273.8 13.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN04810.1 - 6.5e-15 54.6 31.3 2.8e-10 39.4 9.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CDC14 PF08045.6 EDN04811.1 - 1.4e-102 342.2 0.0 1.6e-102 342.0 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component DDHD PF02862.12 EDN04813.1 - 0.037 13.8 8.9 0.037 13.8 6.2 1.0 1 0 0 1 1 1 0 DDHD domain IPP-2 PF04979.9 EDN04813.1 - 0.2 11.9 14.5 0.26 11.5 10.1 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) BORG_CEP PF14957.1 EDN04813.1 - 1.1 10.1 9.1 1.2 10.0 6.3 1.0 1 0 0 1 1 1 0 Cdc42 effector EPL1 PF10513.4 EDN04813.1 - 1.6 8.9 11.1 1.8 8.7 7.7 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like Pex14_N PF04695.8 EDN04813.1 - 1.7 8.7 10.0 2.3 8.2 7.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4613 PF15390.1 EDN04813.1 - 1.9 6.5 8.2 2 6.4 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) FAM176 PF14851.1 EDN04813.1 - 2.1 8.0 4.7 2.6 7.7 3.3 1.2 1 0 0 1 1 1 0 FAM176 family Zip PF02535.17 EDN04813.1 - 2.8 6.8 6.9 2.8 6.8 4.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DDRGK PF09756.4 EDN04813.1 - 3 7.2 12.5 3.2 7.1 8.7 1.0 1 0 0 1 1 1 0 DDRGK domain DUF1764 PF08576.5 EDN04813.1 - 5.5 7.8 11.0 7 7.4 7.6 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) SelP_N PF04592.9 EDN04813.1 - 6.2 6.1 13.3 6.8 5.9 9.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region AIF_C PF14721.1 EDN04813.1 - 6.3 7.0 6.8 7.3 6.8 4.7 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Activator_LAG-3 PF11498.3 EDN04813.1 - 9.1 4.8 21.9 9.6 4.8 15.2 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Folate_carrier PF01770.13 EDN04813.1 - 9.8 4.5 7.9 9.6 4.5 5.4 1.0 1 0 0 1 1 1 0 Reduced folate carrier HTH_29 PF13551.1 EDN04816.1 - 0.037 14.1 0.0 0.07 13.2 0.0 1.5 1 1 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.1 EDN04816.1 - 0.061 12.9 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.1 EDN04816.1 - 0.066 13.2 0.2 0.46 10.5 0.1 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain DDE_Tnp_1_7 PF13843.1 EDN04817.1 - 9.6e-20 70.9 0.9 2.8e-10 39.7 0.1 2.1 1 1 1 2 2 2 2 Transposase IS4 Tubulin PF00091.20 EDN04818.1 - 1.1e-48 165.9 0.9 3.7e-36 124.9 0.1 2.3 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDN04818.1 - 1.5e-40 138.1 0.7 2.4e-40 137.4 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EDN04818.1 - 6.1e-07 29.5 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Asp_Glu_race PF01177.17 EDN04818.1 - 1.8e-05 24.7 0.1 4.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase HSP9_HSP12 PF04119.7 EDN04819.1 - 0.00084 19.3 4.2 0.0013 18.8 2.9 1.3 1 1 0 1 1 1 1 Heat shock protein 9/12 Ipi1_N PF12333.3 EDN04820.1 - 4.8e-29 100.3 0.0 7e-28 96.5 0.0 2.4 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation CLASP_N PF12348.3 EDN04820.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 CLASP N terminal NfI_DNAbd_pre-N PF10524.4 EDN04820.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Pyrid_oxidase_2 PF13883.1 EDN04822.1 - 2.2e-33 115.4 0.0 3.2e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cyclin PF08613.6 EDN04823.1 - 4.4e-13 49.8 0.0 9.1e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EDN04823.1 - 0.0091 15.5 0.1 0.019 14.4 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Alb1 PF09135.6 EDN04824.1 - 0.039 14.5 2.3 0.052 14.1 1.6 1.2 1 0 0 1 1 1 0 Alb1 HSP90 PF00183.13 EDN04824.1 - 0.067 11.5 1.1 0.07 11.5 0.8 1.0 1 0 0 1 1 1 0 Hsp90 protein DUF3072 PF11272.3 EDN04825.1 - 0.17 11.5 1.0 0.26 10.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) APH PF01636.18 EDN04826.1 - 0.00066 19.4 0.1 0.019 14.6 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN04826.1 - 0.01 15.4 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase LBP_BPI_CETP_C PF02886.12 EDN04827.1 - 0.0075 15.5 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain FMO-like PF00743.14 EDN04829.1 - 1.5e-81 274.2 0.0 9.7e-43 146.1 0.0 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EDN04829.1 - 6.1e-14 52.5 0.0 3.9e-10 40.1 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN04829.1 - 8.2e-07 28.9 1.9 0.006 16.3 0.0 3.4 2 2 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EDN04829.1 - 1.4e-06 28.2 0.0 2.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDN04829.1 - 3e-05 23.0 0.0 0.047 12.5 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDN04829.1 - 7.4e-05 22.7 0.0 0.017 15.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDN04829.1 - 0.0029 16.1 0.2 0.026 13.0 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EDN04829.1 - 0.0066 15.5 0.1 0.013 14.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EDN04829.1 - 0.045 14.1 0.1 21 5.6 0.0 3.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDN04829.1 - 0.07 12.0 0.2 3.4 6.4 0.0 2.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lyase_1 PF00206.15 EDN04831.1 - 7.6e-103 343.9 0.0 1.3e-102 343.2 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EDN04831.1 - 3.2e-22 78.3 0.0 9.9e-22 76.7 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.7 EDN04831.1 - 0.16 11.7 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DDE_1 PF03184.14 EDN04832.1 - 1.5e-21 76.5 0.0 1.9e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN04832.1 - 0.0067 16.1 0.0 0.017 14.8 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF2229 PF09989.4 EDN04833.1 - 0.16 11.4 2.1 0.18 11.2 1.5 1.0 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Glyco_transf_20 PF00982.16 EDN04833.1 - 0.19 10.1 2.8 0.22 9.9 1.9 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 20 HDAC4_Gln PF12203.3 EDN04833.1 - 2.3 8.2 12.7 44 4.0 8.8 2.0 1 1 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 Borrelia_P83 PF05262.6 EDN04833.1 - 5.3 5.1 11.2 5.7 5.0 7.8 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3435 PF11917.3 EDN04835.1 - 3.1e-150 500.5 7.5 1.4e-149 498.3 5.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) OmpH PF03938.9 EDN04835.1 - 0.005 16.7 5.0 0.84 9.5 0.0 2.5 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) She9_MDM33 PF05546.6 EDN04835.1 - 0.0058 16.2 4.1 0.016 14.7 2.8 1.8 1 0 0 1 1 1 1 She9 / Mdm33 family Pkinase PF00069.20 EDN04837.1 - 1.3e-18 67.0 0.0 2.4e-11 43.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN04837.1 - 1.8e-06 27.2 0.2 1.9e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Ycf34 PF10718.4 EDN04840.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Hypothetical chloroplast protein Ycf34 Corona_3 PF04694.7 EDN04841.1 - 0.041 13.7 0.1 0.12 12.2 0.1 1.9 1 0 0 1 1 1 0 Coronavirus ORF3 protein APH PF01636.18 EDN04842.1 - 4.2e-08 33.2 0.2 4.3e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN04842.1 - 0.09 12.3 0.0 0.098 12.2 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Myb_DNA-bind_6 PF13921.1 EDN04843.1 - 0.013 15.5 1.2 0.03 14.4 0.8 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain SPX PF03105.14 EDN04846.1 - 0.00038 20.3 6.7 0.00085 19.1 4.5 1.6 1 1 0 1 1 1 1 SPX domain Col_cuticle_N PF01484.12 EDN04846.1 - 0.23 11.1 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Phyto_Pns9_10 PF05878.6 EDN04846.1 - 3.2 6.6 5.0 0.27 10.1 0.3 1.5 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns9/Pns10 Spo12 PF05032.7 EDN04847.1 - 4.6e-16 58.1 0.4 1.1e-15 56.8 0.3 1.7 1 0 0 1 1 1 1 Spo12 family Acyl-CoA_dh_1 PF00441.19 EDN04848.1 - 2e-29 102.6 1.4 3.6e-29 101.8 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDN04848.1 - 3.9e-15 55.0 0.0 9.3e-15 53.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EDN04848.1 - 4.9e-15 56.0 0.1 1.2e-14 54.8 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EDN04848.1 - 2.4e-14 53.7 5.2 2.7e-14 53.5 1.6 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain EST1_DNA_bind PF10373.4 EDN04849.1 - 9.3e-51 172.6 0.6 3.2e-50 170.9 0.0 2.1 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EDN04849.1 - 1.3e-09 38.0 2.0 3e-09 36.9 1.1 1.9 2 0 0 2 2 2 1 Telomerase activating protein Est1 PfkB PF00294.19 EDN04850.1 - 2.4e-65 220.6 0.2 3e-65 220.3 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EDN04850.1 - 0.00034 19.8 0.0 0.00057 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF1770 PF08589.5 EDN04851.1 - 4.2e-21 75.4 0.5 5e-21 75.1 0.4 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.1 EDN04852.1 - 0.0057 16.5 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Uteroglobin PF01099.12 EDN04852.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Uteroglobin family SDA1 PF05285.7 EDN04852.1 - 0.34 10.1 6.4 0.8 8.9 4.5 1.6 1 0 0 1 1 1 0 SDA1 Ribosomal_L2_C PF03947.13 EDN04853.1 - 3.9e-37 126.9 4.2 6.1e-37 126.3 2.9 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EDN04853.1 - 1.9e-12 46.9 0.1 4e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain APH PF01636.18 EDN04854.1 - 6.6e-11 42.4 0.0 2.7e-10 40.3 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EDN04855.1 - 0.00014 21.0 0.0 0.00014 21.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain DUF3473 PF11959.3 EDN04855.1 - 0.038 13.4 0.1 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) Ada_Zn_binding PF02805.11 EDN04856.1 - 1.7e-29 101.1 5.9 3.2e-29 100.2 4.1 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 EDN04856.1 - 5.5e-07 29.2 0.0 1.5e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EDN04856.1 - 0.0019 18.2 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DEAD PF00270.24 EDN04857.1 - 6.9e-11 41.9 0.0 9e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN04857.1 - 0.00039 20.3 0.0 0.0016 18.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.26 EDN04860.1 - 1e-09 38.2 0.6 1.8e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN04860.1 - 9.2e-07 28.8 0.9 1.7e-06 28.0 0.6 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain BH4 PF02180.12 EDN04860.1 - 0.071 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Bcl-2 homology region 4 IFR3_antag PF14754.1 EDN04860.1 - 0.11 11.4 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 Papain-like auto-proteinase DUF3435 PF11917.3 EDN04861.1 - 8.2e-145 482.6 0.3 1.1e-144 482.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DDE_Tnp_1_7 PF13843.1 EDN04864.1 - 7.2e-75 252.2 0.7 2.3e-41 142.0 0.0 2.2 2 0 0 2 2 2 2 Transposase IS4 DDE_1 PF03184.14 EDN04865.1 - 2.2e-41 141.4 0.0 8.3e-41 139.4 0.0 2.0 2 1 0 2 2 2 1 DDE superfamily endonuclease DUF3716 PF12511.3 EDN04865.1 - 9.5e-15 53.9 5.6 1.7e-14 53.1 3.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) HTH_Tnp_Tc5 PF03221.11 EDN04865.1 - 7.1e-11 41.7 0.0 1.9e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN04865.1 - 6.2e-06 25.6 0.8 1.2e-05 24.7 0.5 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_31 PF13560.1 EDN04865.1 - 0.03 14.5 0.3 0.19 11.9 0.2 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DDE_3 PF13358.1 EDN04865.1 - 0.051 13.3 0.1 0.88 9.3 0.0 2.8 2 1 0 2 2 2 0 DDE superfamily endonuclease DUF904 PF06005.7 EDN04865.1 - 0.077 13.2 0.1 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) BCS1_N PF08740.6 EDN04866.1 - 2.1e-35 122.0 0.0 3.3e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN04866.1 - 1.1e-19 70.9 0.0 4.5e-19 68.9 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN04866.1 - 0.0014 18.6 0.1 0.0041 17.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EDN04866.1 - 0.0056 16.1 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN04866.1 - 0.0089 16.8 0.0 0.039 14.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDN04866.1 - 0.033 13.9 0.0 0.14 11.8 0.0 2.0 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) PPV_E1_C PF00519.12 EDN04866.1 - 0.084 11.4 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase AAA_22 PF13401.1 EDN04866.1 - 0.084 13.0 0.0 0.25 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EDN04866.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EDN04866.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EDN04866.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 EDN04866.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EDN04866.1 - 0.14 11.9 0.1 0.51 10.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain Aa_trans PF01490.13 EDN04867.1 - 5.2e-39 133.8 36.4 6.2e-39 133.6 25.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.1 EDN04867.1 - 0.024 14.2 1.1 0.024 14.2 0.8 3.9 5 1 1 6 6 6 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Methyltransf_23 PF13489.1 EDN04868.1 - 4.3e-19 68.8 0.0 6.1e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN04868.1 - 3.5e-07 30.7 0.0 6.4e-06 26.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN04868.1 - 1.3e-05 25.5 0.0 2.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN04868.1 - 1.7e-05 24.4 0.0 0.00031 20.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN04868.1 - 6.2e-05 23.4 0.0 0.00056 20.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN04868.1 - 0.002 18.4 0.0 0.0052 17.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EDN04868.1 - 0.0055 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase FlxA PF14282.1 EDN04870.1 - 1.6 8.7 13.4 0.32 10.9 2.3 2.5 2 0 0 2 2 2 0 FlxA-like protein Retrotrans_gag PF03732.12 EDN04870.1 - 5.2 7.2 15.2 1.2 9.2 2.2 3.3 2 1 1 3 3 3 0 Retrotransposon gag protein RVT_1 PF00078.22 EDN04871.1 - 3.9e-12 46.0 0.1 1.3e-10 40.9 0.0 2.5 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_thumb PF06817.9 EDN04871.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase thumb domain RVT_2 PF07727.9 EDN04871.1 - 0.087 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN04872.1 - 2.3e-16 59.9 0.0 5e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EDN04872.1 - 2e-15 56.2 2.5 4.8e-15 54.9 1.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EDN04872.1 - 0.0028 17.0 0.1 0.0062 15.9 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger DUF3435 PF11917.3 EDN04873.1 - 3.9e-35 121.3 0.0 1.4e-34 119.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) DUF371 PF04027.8 EDN04873.1 - 0.12 12.0 0.0 9.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF371) DegS PF05384.6 EDN04874.1 - 5.2e-05 22.5 1.9 6.9e-05 22.1 1.3 1.1 1 0 0 1 1 1 1 Sensor protein DegS zf-C3HC4 PF00097.20 EDN04874.1 - 0.00026 20.5 8.2 0.00052 19.6 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN04874.1 - 0.0006 19.4 9.6 0.00087 18.9 6.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NTR2 PF15458.1 EDN04874.1 - 0.0016 17.7 1.4 0.0017 17.6 0.9 1.0 1 0 0 1 1 1 1 Nineteen complex-related protein 2 zf-RING_5 PF14634.1 EDN04874.1 - 0.0022 17.6 8.0 0.0036 16.9 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Macoilin PF09726.4 EDN04874.1 - 0.0026 16.1 3.4 0.0031 15.8 2.4 1.0 1 0 0 1 1 1 1 Transmembrane protein TMF_TATA_bd PF12325.3 EDN04874.1 - 0.003 17.2 1.5 0.004 16.8 1.0 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF2730 PF10805.3 EDN04874.1 - 0.0036 17.0 0.5 0.0053 16.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) DivIC PF04977.10 EDN04874.1 - 0.008 15.6 2.0 0.013 14.9 1.4 1.4 1 0 0 1 1 1 1 Septum formation initiator Troponin PF00992.15 EDN04874.1 - 0.0092 16.0 5.3 0.012 15.6 3.6 1.1 1 0 0 1 1 1 1 Troponin ADIP PF11559.3 EDN04874.1 - 0.012 15.5 1.8 0.015 15.1 1.2 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 EDN04874.1 - 0.013 15.4 5.4 0.022 14.7 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Fez1 PF06818.10 EDN04874.1 - 0.014 15.4 1.2 0.017 15.1 0.9 1.1 1 0 0 1 1 1 0 Fez1 Med28 PF11594.3 EDN04874.1 - 0.014 15.6 1.6 0.022 15.0 1.1 1.3 1 1 0 1 1 1 0 Mediator complex subunit 28 FlaC_arch PF05377.6 EDN04874.1 - 0.016 15.1 1.9 4.7 7.1 1.4 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) HALZ PF02183.13 EDN04874.1 - 0.022 14.4 1.5 0.033 13.9 0.6 1.5 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF4618 PF15397.1 EDN04874.1 - 0.027 13.8 1.0 0.034 13.5 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) GOLGA2L5 PF15070.1 EDN04874.1 - 0.029 12.9 0.2 0.033 12.6 0.1 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Fib_alpha PF08702.5 EDN04874.1 - 0.03 14.4 0.7 0.046 13.8 0.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spectrin PF00435.16 EDN04874.1 - 0.03 14.5 0.8 0.041 14.1 0.6 1.2 1 0 0 1 1 1 0 Spectrin repeat RmuC PF02646.11 EDN04874.1 - 0.032 13.0 1.2 0.041 12.7 0.8 1.1 1 0 0 1 1 1 0 RmuC family HAUS5 PF14817.1 EDN04874.1 - 0.036 12.6 2.7 0.043 12.3 1.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 zf-RING_2 PF13639.1 EDN04874.1 - 0.039 13.7 9.4 0.088 12.6 6.5 1.6 1 1 0 1 1 1 0 Ring finger domain DUF641 PF04859.7 EDN04874.1 - 0.042 13.6 1.2 0.055 13.2 0.9 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.3 EDN04874.1 - 0.045 13.5 1.8 0.076 12.8 1.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 EDN04874.1 - 0.046 13.5 5.0 0.068 13.0 3.5 1.2 1 0 0 1 1 1 0 Tropomyosin like Cep57_CLD PF14073.1 EDN04874.1 - 0.05 13.4 2.3 0.063 13.1 1.6 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 zf-C3HC4_2 PF13923.1 EDN04874.1 - 0.054 13.5 9.2 0.1 12.6 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1192 PF06698.6 EDN04874.1 - 0.067 13.0 3.1 0.087 12.6 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4164 PF13747.1 EDN04874.1 - 0.093 12.8 5.0 0.13 12.3 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF3373 PF11853.3 EDN04874.1 - 0.094 11.2 0.2 0.11 11.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Seryl_tRNA_N PF02403.17 EDN04874.1 - 0.096 12.7 1.8 0.13 12.2 1.2 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain FadA PF09403.5 EDN04874.1 - 0.12 12.4 1.8 0.15 12.0 1.2 1.1 1 0 0 1 1 1 0 Adhesion protein FadA Prefoldin_2 PF01920.15 EDN04874.1 - 0.13 12.0 4.3 0.26 11.0 3.0 1.5 1 1 0 1 1 1 0 Prefoldin subunit Bunya_RdRp PF04196.7 EDN04874.1 - 0.13 10.2 0.1 0.16 9.9 0.0 1.0 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase Flg_hook PF02120.11 EDN04874.1 - 0.13 11.9 0.3 0.18 11.5 0.2 1.1 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK SOCS_box PF07525.11 EDN04874.1 - 0.15 11.9 0.9 0.96 9.3 0.2 2.3 2 0 0 2 2 2 0 SOCS box bZIP_1 PF00170.16 EDN04874.1 - 0.2 11.6 5.3 1.6 8.7 3.7 2.1 1 1 0 1 1 1 0 bZIP transcription factor IncA PF04156.9 EDN04874.1 - 0.25 10.9 3.1 0.35 10.4 2.2 1.2 1 0 0 1 1 1 0 IncA protein CENP-Q PF13094.1 EDN04874.1 - 0.32 11.0 6.3 0.81 9.6 4.5 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1843 PF08898.5 EDN04874.1 - 1.3 9.0 4.4 6.2 6.9 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) Gasdermin PF04598.7 EDN04875.1 - 0.0015 17.3 1.3 0.0024 16.7 0.9 1.3 1 0 0 1 1 1 1 Gasdermin family DUF16 PF01519.11 EDN04875.1 - 0.0019 18.4 7.0 0.19 11.9 0.3 2.6 2 1 0 2 2 2 2 Protein of unknown function DUF16 HWE_HK PF07536.9 EDN04875.1 - 0.016 15.5 3.5 0.027 14.8 1.2 2.2 1 1 1 2 2 2 0 HWE histidine kinase DUF3502 PF12010.3 EDN04875.1 - 0.081 12.8 0.1 7.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3502) Syntaxin-6_N PF09177.6 EDN04875.1 - 0.12 12.7 9.5 3.5 8.1 0.6 3.5 3 1 1 4 4 4 0 Syntaxin 6, N-terminal MutS_IV PF05190.13 EDN04875.1 - 0.41 10.8 3.2 22 5.3 0.0 2.9 2 1 0 2 2 2 0 MutS family domain IV SYF2 PF08231.7 EDN04875.1 - 0.49 10.5 3.4 2 8.5 0.1 2.3 2 0 0 2 2 2 0 SYF2 splicing factor DUF327 PF03885.8 EDN04875.1 - 0.84 9.4 4.7 2.3 8.0 0.1 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF327) DUF4132 PF13569.1 EDN04875.1 - 2.6 7.5 6.8 3 7.3 2.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4132) Myb_DNA-binding PF00249.26 EDN04877.1 - 1.5e-11 44.1 0.2 5.7e-10 39.1 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN04877.1 - 2.4e-07 30.7 0.4 3.3e-06 27.1 0.1 2.3 1 1 1 2 2 2 1 Myb-like DNA-binding domain BCS1_N PF08740.6 EDN04878.1 - 2.7e-40 137.9 0.1 5.6e-40 136.9 0.0 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN04878.1 - 1.1e-19 70.9 0.0 3.9e-19 69.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN04878.1 - 0.00049 20.1 0.4 0.0011 18.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EDN04878.1 - 0.0076 17.0 0.0 0.043 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN04878.1 - 0.013 14.9 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDN04878.1 - 0.052 13.2 0.0 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN04878.1 - 0.066 13.3 0.0 0.27 11.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EDN04878.1 - 0.086 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 EDN04878.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EDN04878.1 - 0.11 12.3 0.2 0.48 10.2 0.1 2.2 2 1 0 2 2 2 0 AAA domain BTB PF00651.26 EDN04882.1 - 0.00028 20.8 0.0 0.00051 20.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Chromo PF00385.19 EDN04883.1 - 3.2e-06 26.7 0.4 6.3e-06 25.7 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain BAR PF03114.13 EDN04884.1 - 1.3e-15 57.5 0.6 1.4e-15 57.4 0.4 1.0 1 0 0 1 1 1 1 BAR domain Bromodomain PF00439.20 EDN04885.1 - 1.2e-26 92.3 1.0 8.6e-25 86.4 0.2 2.5 2 0 0 2 2 2 2 Bromodomain SnAC PF14619.1 EDN04885.1 - 2.1e-18 66.2 1.6 2.1e-18 66.2 1.1 2.5 2 2 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex CoA_binding PF02629.14 EDN04886.1 - 3.7e-25 88.2 0.2 4.5e-25 87.9 0.2 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding_2 PF13380.1 EDN04886.1 - 0.0038 17.3 0.1 0.0053 16.9 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain Radical_SAM PF04055.16 EDN04887.1 - 1.3e-17 64.4 0.0 2.7e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily His_biosynth PF00977.16 EDN04888.1 - 5.7e-28 97.7 0.0 1.9e-27 96.0 0.0 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 EDN04888.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family STE PF02200.11 EDN04890.1 - 1e-38 131.8 0.3 2.1e-38 130.8 0.1 1.6 2 0 0 2 2 1 1 STE like transcription factor zf-C2H2 PF00096.21 EDN04890.1 - 3.6e-12 45.8 10.4 8.8e-07 28.9 0.6 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN04890.1 - 6e-10 38.7 10.9 5e-05 23.3 1.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDN04890.1 - 2.1e-09 37.1 3.8 2.1e-09 37.1 2.6 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EDN04890.1 - 0.00093 19.0 0.2 0.0036 17.1 0.0 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger NOA36 PF06524.7 EDN04890.1 - 0.0014 17.9 4.5 0.0023 17.2 3.1 1.2 1 0 0 1 1 1 1 NOA36 protein zf-C2H2_jaz PF12171.3 EDN04890.1 - 0.0023 18.0 0.3 0.11 12.6 0.0 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Rtf2 PF04641.7 EDN04890.1 - 0.0045 16.2 0.8 0.009 15.2 0.5 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-TRAF PF02176.13 EDN04890.1 - 0.02 15.2 2.2 0.036 14.4 1.5 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2HC_2 PF13913.1 EDN04890.1 - 0.043 13.5 5.2 0.08 12.6 0.3 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FYDLN_acid PF09538.5 EDN04890.1 - 0.052 14.1 2.4 0.14 12.7 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-RING_3 PF14369.1 EDN04890.1 - 0.062 13.2 0.3 0.16 11.9 0.2 1.7 1 0 0 1 1 1 0 zinc-finger DUF4242 PF14026.1 EDN04892.1 - 0.017 15.1 0.0 0.082 13.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4242) PB1-F2 PF11986.3 EDN04893.1 - 0.078 13.0 1.7 0.17 11.9 1.2 1.6 1 0 0 1 1 1 0 Influenza A Proapoptotic protein DUF327 PF03885.8 EDN04893.1 - 0.12 12.1 3.3 2.4 7.9 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF327) HWE_HK PF07536.9 EDN04893.1 - 0.22 12.0 2.1 0.55 10.7 0.8 2.2 1 1 1 2 2 2 0 HWE histidine kinase DUF2267 PF10025.4 EDN04893.1 - 0.25 11.3 3.7 0.36 10.8 1.7 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) DUF1779 PF08680.5 EDN04893.1 - 0.27 11.0 4.0 0.4 10.5 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) HalX PF08663.5 EDN04893.1 - 0.36 10.8 7.6 0.38 10.7 1.3 3.1 2 1 1 3 3 3 0 HalX domain Prominin PF05478.6 EDN04893.1 - 0.38 8.2 8.8 0.19 9.2 1.6 1.9 1 1 1 2 2 2 0 Prominin DUF16 PF01519.11 EDN04893.1 - 0.58 10.4 4.5 2.6 8.3 3.1 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 V_ATPase_I PF01496.14 EDN04893.1 - 0.63 7.8 3.3 0.79 7.4 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Salp15 PF12115.3 EDN04893.1 - 2.8 8.1 5.7 67 3.7 4.0 2.3 1 1 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation APH PF01636.18 EDN04895.1 - 1.1e-08 35.0 0.4 1.1e-07 31.7 0.5 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family DAN PF03045.10 EDN04896.1 - 0.024 14.0 1.7 24 4.3 0.0 2.9 1 1 2 3 3 3 0 DAN domain DUF902 PF06001.8 EDN04896.1 - 0.34 11.0 13.0 8.9 6.5 1.7 3.3 1 1 2 3 3 3 0 Domain of Unknown Function (DUF902) uDENN PF03456.13 EDN04896.1 - 0.39 10.7 17.8 7.2 6.6 0.1 4.5 1 1 2 3 3 3 0 uDENN domain MFS_2 PF13347.1 EDN04897.1 - 1.3e-05 23.7 3.4 1.4e-05 23.6 1.3 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein Daxx PF03344.10 EDN04897.1 - 0.069 11.6 3.4 0.1 11.0 2.3 1.1 1 0 0 1 1 1 0 Daxx Family PUCC PF03209.10 EDN04897.1 - 0.12 11.0 3.9 0.66 8.6 0.1 2.3 2 0 0 2 2 2 0 PUCC protein Glycoprotein_B PF00606.13 EDN04897.1 - 0.17 9.8 0.4 0.26 9.2 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B MSP1_C PF07462.6 EDN04897.1 - 0.57 8.5 1.9 0.79 8.0 1.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Na_H_Exchanger PF00999.16 EDN04898.1 - 1.6e-60 204.6 38.0 2.4e-60 204.0 26.3 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM_2 PF13703.1 EDN04898.1 - 4.4 7.5 10.3 0.87 9.8 0.2 4.1 3 1 0 3 3 3 0 PepSY-associated TM helix ADH_zinc_N PF00107.21 EDN04899.1 - 3.7e-22 78.2 0.4 5.4e-22 77.7 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN04899.1 - 1.7e-06 27.7 0.0 3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EDN04899.1 - 0.00075 20.4 0.2 0.0011 19.9 0.2 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EDN04899.1 - 0.056 13.0 0.2 0.093 12.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EDN04899.1 - 0.074 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain APH PF01636.18 EDN04900.1 - 8.4e-14 51.8 0.0 2e-13 50.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EDN04900.1 - 0.018 13.7 0.1 0.2 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 EDN04900.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Chromo PF00385.19 EDN04902.1 - 3.1e-10 39.5 0.9 0.00019 21.0 0.2 2.7 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain p450 PF00067.17 EDN04903.1 - 3.8e-24 85.0 1.3 1.8e-13 49.8 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 AAA_16 PF13191.1 EDN04903.1 - 0.18 11.7 0.7 0.51 10.2 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain DBINO PF13892.1 EDN04904.1 - 2.7e-27 95.4 18.4 7.5e-27 94.0 10.0 4.5 4 1 1 5 5 5 2 DNA-binding domain MxiH PF09392.5 EDN04904.1 - 0.0019 18.7 0.3 1.1 9.9 0.0 3.6 3 1 0 3 3 3 1 Type III secretion needle MxiH like AAA PF00004.24 EDN04906.1 - 9e-12 45.3 0.3 4.4e-11 43.1 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-CCHC PF00098.18 EDN04909.1 - 0.015 15.2 5.6 0.024 14.5 3.9 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.1 EDN04909.1 - 1.7 8.1 6.0 0.27 10.7 1.0 1.9 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 EDN04910.1 - 2.8e-24 85.6 0.0 5.5e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EDN04910.1 - 0.0023 17.2 0.1 0.0079 15.5 0.0 2.0 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_thumb PF06817.9 EDN04910.1 - 0.057 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase thumb domain DUF1729 PF08354.5 EDN04911.1 - 0.19 11.5 0.6 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) RRM_1 PF00076.17 EDN04912.1 - 6.3e-51 169.8 0.0 4.1e-21 74.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN04912.1 - 2.8e-36 123.2 0.0 1e-13 51.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN04912.1 - 2e-20 72.3 0.0 2.9e-10 39.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDN04912.1 - 0.0002 21.0 0.0 0.14 11.9 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EDN04912.1 - 0.00065 19.5 0.0 0.68 9.9 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) PROL5-SMR PF15621.1 EDN04913.1 - 1.2 9.5 5.6 1.5 9.2 3.9 1.2 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Neisseria_TspB PF05616.8 EDN04913.1 - 4.9 5.4 9.9 5.2 5.3 6.8 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein AflR PF08493.5 EDN04913.1 - 5.1 6.0 6.4 6 5.8 4.4 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein DUF3505 PF12013.3 EDN04914.1 - 2.3e-38 130.7 5.5 2.3e-38 130.7 3.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) Ribonuc_red_lgC PF02867.10 EDN04916.1 - 1.4e-135 452.9 0.0 3.2e-91 306.5 0.0 2.1 1 1 1 2 2 2 2 Ribonucleotide reductase, barrel domain YppG PF14179.1 EDN04919.1 - 0.73 10.4 11.7 0.35 11.5 6.1 1.8 2 0 0 2 2 2 0 YppG-like protein Tom37_C PF11801.3 EDN04920.1 - 0.0021 17.9 1.3 0.0021 17.9 0.9 2.2 2 0 0 2 2 2 1 Tom37 C-terminal domain Nucleo_P87 PF07267.6 EDN04920.1 - 9.6 4.7 11.0 15 4.1 7.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Yae1_N PF09811.4 EDN04921.1 - 0.13 11.7 8.9 0.21 11.1 6.2 1.3 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Helicase_C PF00271.26 EDN04922.1 - 1.1e-11 44.4 0.0 3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ACTH_domain PF00976.13 EDN04924.1 - 0.88 9.4 6.2 1.2 8.9 0.1 3.2 3 0 0 3 3 3 0 Corticotropin ACTH domain DUF3505 PF12013.3 EDN04925.1 - 6.4e-16 58.5 0.2 7.9e-15 55.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) KH_3 PF13014.1 EDN04926.1 - 0.029 14.0 1.6 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 KH domain DUF4219 PF13961.1 EDN04928.1 - 0.005 16.2 0.2 0.012 14.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.18 EDN04928.1 - 1.3 9.0 4.3 2.2 8.3 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle ACTH_domain PF00976.13 EDN04929.1 - 0.88 9.4 6.2 1.2 8.9 0.1 3.2 3 0 0 3 3 3 0 Corticotropin ACTH domain KH_3 PF13014.1 EDN04932.1 - 0.3 10.7 1.6 5.7 6.7 0.0 2.6 2 0 0 2 2 2 0 KH domain DUF3505 PF12013.3 EDN04935.1 - 2.5e-05 24.4 0.4 2.5e-05 24.4 0.3 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3505) DUF3505 PF12013.3 EDN04938.1 - 6.4e-16 58.5 0.2 7.9e-15 55.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) DUF1426 PF07234.6 EDN04939.1 - 0.15 11.7 0.1 23 4.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1426) DEAD PF00270.24 EDN04941.1 - 1.2e-15 57.4 0.0 3.7e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN04941.1 - 2.5e-15 56.1 0.1 7.4e-15 54.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN04941.1 - 1.2e-06 28.4 0.5 5.3e-05 23.1 0.0 3.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDN04941.1 - 0.026 13.3 0.0 0.058 12.1 0.0 1.5 1 0 0 1 1 1 0 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN04944.1 - 2.4e-26 91.4 0.3 4.9e-13 48.7 0.1 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EDN04944.1 - 8.7e-13 48.1 0.1 5.2e-10 39.0 0.0 3.0 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF3505 PF12013.3 EDN04944.1 - 5.1e-11 42.7 1.0 5.1e-11 42.7 0.7 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3505) AAA_11 PF13086.1 EDN04944.1 - 0.038 13.5 0.0 0.038 13.5 0.0 3.4 4 0 0 4 4 4 0 AAA domain T4SS-DNA_transf PF02534.9 EDN04944.1 - 0.047 12.2 0.0 0.09 11.3 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Myb_DNA-binding PF00249.26 EDN04948.1 - 0.00084 19.3 0.6 0.0036 17.3 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN04948.1 - 0.035 14.2 0.3 0.035 14.2 0.2 2.3 3 0 0 3 3 3 0 Myb-like DNA-binding domain DUF573 PF04504.9 EDN04948.1 - 0.04 14.1 2.3 0.093 13.0 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF573 Myb_DNA-bind_4 PF13837.1 EDN04948.1 - 0.063 13.4 1.8 0.68 10.0 1.2 2.3 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain Helicase_C PF00271.26 EDN04949.1 - 1.7e-15 56.5 0.1 4.4e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Aft1_HRR PF11787.3 EDN04949.1 - 2.7 9.1 6.7 0.23 12.5 0.4 2.5 2 1 0 2 2 2 0 Aft1 HRR domain FlxA PF14282.1 EDN04953.1 - 0.1 12.5 10.3 0.24 11.3 2.4 2.5 2 0 0 2 2 2 0 FlxA-like protein Retrotrans_gag PF03732.12 EDN04953.1 - 6.3 6.9 15.5 0.85 9.7 1.8 3.4 1 1 2 3 3 3 0 Retrotransposon gag protein rve PF00665.21 EDN04954.1 - 1.4e-16 60.6 0.0 7.2e-16 58.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EDN04954.1 - 2.5e-11 43.3 0.4 4.9e-10 39.1 0.0 2.5 2 1 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EDN04954.1 - 0.0033 16.8 0.1 0.0082 15.5 0.0 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger DUF1729 PF08354.5 EDN04955.1 - 0.19 11.5 0.6 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) CFEM PF05730.6 EDN04957.1 - 1.3e-12 47.3 6.0 2e-12 46.7 4.2 1.3 1 0 0 1 1 1 1 CFEM domain Sas10_Utp3 PF04000.10 EDN04960.1 - 1.3e-14 54.1 0.1 2.3e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Mpp10 PF04006.7 EDN04960.1 - 0.023 13.0 3.9 0.037 12.3 2.7 1.3 1 0 0 1 1 1 0 Mpp10 protein Ebola_NP PF05505.7 EDN04960.1 - 1.4 6.8 4.6 1.9 6.4 3.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Cwf_Cwc_15 PF04889.7 EDN04960.1 - 3.5 7.2 11.4 0.065 12.9 2.8 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.8 EDN04960.1 - 5.9 4.5 5.1 9.6 3.8 3.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi Methyltransf_23 PF13489.1 EDN04961.1 - 1.7e-18 66.8 0.0 2.8e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN04961.1 - 1.3e-05 24.7 0.0 0.00023 20.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN04961.1 - 1.8e-05 25.2 0.0 0.00034 21.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN04961.1 - 0.0036 17.7 0.0 0.0066 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN04961.1 - 0.09 13.2 0.0 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain 5_nucleotid_C PF02872.13 EDN04962.1 - 2.1e-38 131.7 0.0 9.9e-38 129.5 0.0 2.1 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EDN04962.1 - 7.2e-09 35.3 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase His_Phos_1 PF00300.17 EDN04963.1 - 4.8e-10 39.7 0.0 4.3e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EDN04963.1 - 0.035 13.4 0.4 0.11 11.8 0.3 1.7 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) UQ_con PF00179.21 EDN04964.1 - 1.2e-51 173.7 0.0 1.4e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDN04964.1 - 3.2e-06 26.9 0.0 3.6e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDN04964.1 - 0.062 13.2 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.18 EDN04965.1 - 1.3e-111 372.5 0.1 3.2e-111 371.2 0.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain Peptidase_C1_2 PF03051.10 EDN04966.1 - 4.2e-148 493.5 0.0 5.1e-148 493.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EDN04966.1 - 3.2e-06 27.1 0.1 0.028 14.3 0.2 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Thiolase_N PF00108.18 EDN04967.1 - 3.8e-94 314.5 0.2 5e-94 314.1 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDN04967.1 - 1.7e-37 127.5 0.5 1.7e-37 127.5 0.3 1.9 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EDN04967.1 - 9.2e-05 22.0 0.9 0.0018 17.7 0.2 2.7 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EDN04967.1 - 0.55 9.9 5.3 15 5.3 0.0 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cation_efflux PF01545.16 EDN04968.1 - 3.5e-53 180.5 12.1 3.5e-53 180.5 8.4 3.1 4 0 0 4 4 4 2 Cation efflux family Glyco_trans_1_4 PF13692.1 EDN04970.1 - 1.1e-28 100.0 0.0 1.9e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EDN04970.1 - 0.0097 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF4133 PF13571.1 EDN04971.1 - 5.8 7.2 6.2 1.1 9.5 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) TFIIIC_delta PF12657.2 EDN04972.1 - 1.6e-29 102.8 6.7 1.4e-19 70.4 0.6 2.6 2 1 1 3 3 3 2 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EDN04972.1 - 4.9e-20 71.2 0.2 2.2e-09 37.0 0.2 2.4 2 0 0 2 2 2 2 Putative zinc-finger of transcription factor IIIC complex Mito_carr PF00153.22 EDN04973.1 - 4.9e-56 186.4 6.7 7.8e-20 70.3 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein UQ_con PF00179.21 EDN04975.1 - 4.4e-43 146.0 0.0 4.9e-43 145.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EMP70 PF02990.11 EDN04977.1 - 4.5e-180 599.5 1.7 5.4e-180 599.2 1.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 EF-hand_7 PF13499.1 EDN04978.1 - 2.3e-32 110.9 15.1 4.4e-13 49.1 0.5 2.8 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 EDN04978.1 - 2.4e-24 82.7 12.0 3.7e-08 32.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EDN04978.1 - 6.5e-24 81.6 1.5 2.9e-05 23.5 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EDN04978.1 - 1.2e-17 62.3 8.4 6.8e-05 22.0 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EDN04978.1 - 6.3e-15 54.5 12.8 2e-05 24.0 1.3 4.0 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EDN04978.1 - 9.6e-09 34.9 4.7 0.0019 17.9 0.1 3.2 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EDN04978.1 - 0.0021 17.9 0.2 0.086 12.7 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 EDN04978.1 - 0.0031 17.1 1.0 1.5 8.5 0.0 3.2 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.4 EDN04978.1 - 0.038 14.0 0.1 0.88 9.6 0.1 2.6 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.10 EDN04978.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain Med4 PF10018.4 EDN04979.1 - 5.9e-32 110.5 0.0 9.6e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 MFS_1 PF07690.11 EDN04980.1 - 1.2e-15 57.0 7.7 1.2e-15 57.0 5.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EDN04982.1 - 1e-23 83.6 24.2 5.8e-22 77.8 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 EDN04983.1 - 0.00017 21.2 1.0 0.0018 17.9 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EDN04983.1 - 0.00025 20.5 0.0 0.0006 19.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain AMP-binding PF00501.23 EDN04984.1 - 1.1e-76 257.9 0.0 1.6e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN04984.1 - 0.032 15.1 0.5 0.079 13.9 0.4 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Glyco_hydro_92 PF07971.7 EDN04986.1 - 4.3e-166 553.4 0.0 5.4e-166 553.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF4519 PF15012.1 EDN04987.1 - 8.2 6.4 7.8 20 5.2 5.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) RabGAP-TBC PF00566.13 EDN04988.1 - 2e-19 69.9 0.0 1.3e-18 67.3 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Myosin_tail_1 PF01576.14 EDN04988.1 - 0.0096 13.6 26.0 0.017 12.9 18.0 1.2 1 0 0 1 1 1 1 Myosin tail FUSC PF04632.7 EDN04988.1 - 0.48 8.7 8.5 1.1 7.5 5.9 1.6 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_S46 PF10459.4 EDN04988.1 - 1.1 7.5 11.5 1.7 6.9 8.0 1.2 1 0 0 1 1 1 0 Peptidase S46 DUF2972 PF11186.3 EDN04988.1 - 1.6 8.5 8.3 0.46 10.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2972) DUF3597 PF12200.3 EDN04988.1 - 2.4 8.5 6.4 0.71 10.2 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) EMP24_GP25L PF01105.19 EDN04988.1 - 4.1 7.0 8.4 3 7.5 0.6 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 EDN04988.1 - 4.7 5.2 19.4 0.27 9.3 3.3 2.9 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Spc24 PF08286.6 EDN04988.1 - 7.1 6.3 12.9 10 5.8 3.0 2.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DNA_topoisoIV PF00521.15 EDN04990.1 - 5.2e-137 457.1 0.0 1e-136 456.1 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EDN04990.1 - 2.2e-34 118.1 4.4 5.9e-34 116.7 3.1 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EDN04990.1 - 3.7e-13 49.3 0.1 5.8e-12 45.4 0.0 3.0 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EDN04990.1 - 5.6e-11 42.1 0.1 2.6e-10 39.9 0.0 2.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reticulon PF02453.12 EDN04992.1 - 1.8e-38 131.8 2.2 2.5e-38 131.3 1.5 1.2 1 0 0 1 1 1 1 Reticulon DUF3375 PF11855.3 EDN04992.1 - 0.0039 15.9 0.6 0.0058 15.4 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3375) Cytochrome-c551 PF10643.4 EDN04992.1 - 0.0068 15.7 0.7 0.015 14.5 0.5 1.5 1 1 0 1 1 1 1 Photosystem P840 reaction-centre cytochrome c-551 VGLL4 PF15245.1 EDN04992.1 - 0.16 11.7 1.3 0.24 11.2 0.9 1.2 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Acyl-CoA_dh_1 PF00441.19 EDN04993.1 - 3e-31 108.5 1.8 3e-31 108.5 1.3 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EDN04993.1 - 1.5e-22 80.2 0.4 3.4e-22 79.1 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EDN04993.1 - 1.9e-16 60.5 1.3 1.9e-16 60.5 0.9 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDN04993.1 - 2.3e-05 23.8 0.2 0.00021 20.7 0.1 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain INCENP_ARK-bind PF03941.10 EDN04994.1 - 1.9e-21 75.6 1.2 7.4e-21 73.7 0.8 2.1 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region APH PF01636.18 EDN04995.1 - 4.2e-07 29.9 0.1 5.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3624 PF12292.3 EDN04995.1 - 0.26 11.6 6.3 0.56 10.6 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) PDZ_1 PF12812.2 EDN04997.1 - 1.3e-53 178.7 0.2 7.1e-35 118.7 0.0 2.9 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.1 EDN04997.1 - 2.4e-14 53.3 0.1 8.2e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 EDN04997.1 - 5.6e-14 51.7 0.0 8.9e-06 25.5 0.0 3.9 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.19 EDN04997.1 - 1.3e-11 44.4 0.0 1.8e-05 24.8 0.0 3.6 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EDN04997.1 - 1.2e-05 25.0 0.1 0.071 12.9 0.0 3.3 3 0 0 3 3 3 2 Tricorn protease PDZ domain Trypsin PF00089.21 EDN04997.1 - 1.9e-05 24.3 0.0 6.2e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.16 EDN04997.1 - 0.066 12.6 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 EDN04997.1 - 0.1 11.9 0.2 0.16 11.2 0.2 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.4 EDN04997.1 - 0.16 10.3 0.3 0.33 9.3 0.1 1.5 2 0 0 2 2 2 0 Peptidase S46 SSXT PF05030.7 EDN04998.1 - 0.0025 17.3 5.5 0.49 10.0 0.0 2.7 3 0 0 3 3 3 2 SSXT protein (N-terminal region) Macoilin PF09726.4 EDN04998.1 - 0.21 9.8 6.7 0.2 9.8 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein TPR_11 PF13414.1 EDN04999.1 - 1.8e-08 33.8 1.6 1.8e-05 24.2 0.2 2.7 1 1 1 2 2 2 2 TPR repeat TPR_19 PF14559.1 EDN04999.1 - 0.014 15.7 0.0 0.036 14.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDN04999.1 - 0.024 14.2 5.5 4.1 7.1 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDN04999.1 - 0.032 14.1 0.6 20 5.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Pox_T4_N PF04491.7 EDN04999.1 - 0.1 12.4 0.0 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus FSH1 PF03959.8 EDN05000.1 - 5.5e-27 94.5 0.0 1e-26 93.6 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EDN05000.1 - 8.9e-10 38.8 0.1 4.5e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN05000.1 - 8.1e-05 22.4 0.0 0.0002 21.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN05000.1 - 0.017 14.7 0.3 0.99 8.9 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 EDN05000.1 - 0.034 13.4 0.0 0.083 12.1 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family DDE_1 PF03184.14 EDN05001.1 - 9.1e-37 126.2 0.0 1.6e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN05001.1 - 1.5e-05 24.6 0.0 5.8e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN05001.1 - 0.0054 16.2 0.6 0.0054 16.2 0.4 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain TraG_N PF07916.6 EDN05001.1 - 0.73 8.1 3.6 1.1 7.6 2.5 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF2229 PF09989.4 EDN05001.1 - 5.3 6.4 8.7 37 3.6 6.0 2.1 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DS PF01916.12 EDN05002.1 - 1.3e-140 467.7 0.1 1.5e-140 467.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EDN05002.1 - 0.11 11.5 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Carbamoyltransferase MCPsignal PF00015.16 EDN05003.1 - 0.0013 18.3 2.9 0.0018 17.8 2.0 1.2 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain IncA PF04156.9 EDN05003.1 - 0.0049 16.4 0.9 0.0074 15.9 0.6 1.3 1 0 0 1 1 1 1 IncA protein Laminin_II PF06009.7 EDN05003.1 - 0.005 16.5 1.5 0.0079 15.9 0.4 1.7 1 1 0 1 1 1 1 Laminin Domain II BLOC1_2 PF10046.4 EDN05003.1 - 0.0053 16.8 2.1 0.021 14.9 1.4 2.0 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.7 EDN05003.1 - 0.014 15.1 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 EDN05003.1 - 0.017 13.5 0.5 0.021 13.3 0.4 1.0 1 0 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.3 EDN05003.1 - 0.021 14.5 9.1 0.069 12.8 2.9 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Phage_lysis PF03245.8 EDN05003.1 - 0.031 14.2 3.8 0.091 12.7 2.2 1.9 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein DUF641 PF04859.7 EDN05003.1 - 0.035 13.8 3.5 0.08 12.7 0.5 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF1342 PF07072.6 EDN05003.1 - 0.04 13.5 1.3 0.35 10.4 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1342) Fib_alpha PF08702.5 EDN05003.1 - 0.055 13.5 2.1 3.9 7.5 0.6 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2317 PF10079.4 EDN05003.1 - 0.065 11.8 0.6 0.072 11.6 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF1664 PF07889.7 EDN05003.1 - 0.096 12.4 2.5 0.22 11.3 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CALCOCO1 PF07888.6 EDN05003.1 - 0.14 10.4 3.7 0.15 10.3 2.6 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like V_ATPase_I PF01496.14 EDN05003.1 - 0.14 9.9 0.5 0.15 9.8 0.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 EDN05003.1 - 0.18 11.3 3.0 2.1 7.8 2.1 2.1 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Apolipoprotein PF01442.13 EDN05003.1 - 0.28 10.6 5.2 0.4 10.1 3.6 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Val_tRNA-synt_C PF10458.4 EDN05003.1 - 0.32 11.0 5.6 0.43 10.6 0.5 2.5 1 1 1 2 2 2 0 Valyl tRNA synthetase tRNA binding arm PspA_IM30 PF04012.7 EDN05003.1 - 0.42 9.9 6.0 0.51 9.6 0.3 2.1 1 1 1 2 2 2 0 PspA/IM30 family Syntaxin-6_N PF09177.6 EDN05003.1 - 0.57 10.6 2.9 2.8 8.3 0.1 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.3 EDN05003.1 - 0.58 10.0 6.4 1.4e+02 2.3 4.7 2.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HisKA_3 PF07730.8 EDN05003.1 - 0.71 10.2 5.3 19 5.6 3.7 2.5 1 1 0 1 1 1 0 Histidine kinase DUF1049 PF06305.6 EDN05003.1 - 0.78 9.2 2.9 1.9 7.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DASH_Spc34 PF08657.5 EDN05003.1 - 0.81 9.3 6.3 1 8.9 4.3 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 FlaC_arch PF05377.6 EDN05003.1 - 0.88 9.5 5.2 1.8 8.4 0.4 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.4 EDN05003.1 - 1.5 8.6 10.8 44 3.9 7.5 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 EDN05003.1 - 3.7 7.4 7.8 46 3.9 5.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Pox_A_type_inc PF04508.7 EDN05003.1 - 3.8 7.5 15.5 1.7 8.6 0.7 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF919 PF06034.6 EDN05003.1 - 5.5 6.6 7.3 13 5.5 1.3 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Med9 PF07544.8 EDN05003.1 - 8 6.2 9.8 6.9e+02 0.0 6.3 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 peroxidase PF00141.18 EDN05004.1 - 1.1e-49 169.0 0.0 1.5e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4360 PF14273.1 EDN05007.1 - 1.2e-33 116.3 0.2 1.3e-33 116.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pyridoxal_deC PF00282.14 EDN05008.1 - 3.4e-79 266.0 0.0 4.3e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EDN05008.1 - 5.6e-05 22.0 0.0 9.7e-05 21.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EDN05008.1 - 0.031 13.3 0.1 0.12 11.3 0.0 1.9 2 1 1 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family HC2 PF07382.6 EDN05009.1 - 1.3e-05 25.2 29.7 0.00023 21.0 9.3 3.3 2 1 0 3 3 3 2 Histone H1-like nucleoprotein HC2 SBDS_C PF09377.5 EDN05011.1 - 1.1e-45 154.3 0.0 1.8e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EDN05011.1 - 3.1e-27 94.1 0.1 5.7e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein PBP1_TM PF14812.1 EDN05011.1 - 0.025 14.8 0.9 0.078 13.2 0.6 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EnY2 PF10163.4 EDN05011.1 - 0.06 13.2 0.1 0.49 10.3 0.0 2.2 2 0 0 2 2 2 0 Transcription factor e(y)2 NST1 PF13945.1 EDN05011.1 - 0.33 10.9 9.5 2.6 8.0 0.1 3.0 3 0 0 3 3 3 0 Salt tolerance down-regulator Peptidase_S10 PF00450.17 EDN05012.1 - 1.1e-130 436.5 1.2 1.3e-130 436.2 0.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EDN05012.1 - 2.7e-05 24.3 0.0 5.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EDN05012.1 - 0.00013 21.9 0.1 0.0039 17.0 0.0 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Ribosomal_S13 PF00416.17 EDN05013.1 - 1.2e-41 141.4 2.8 1.4e-41 141.2 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EDN05013.1 - 0.0091 14.5 0.1 0.011 14.3 0.0 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HNH_2 PF13391.1 EDN05015.1 - 1e-09 38.0 0.1 2.5e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease SNF5 PF04855.7 EDN05015.1 - 0.024 14.0 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 GMC_oxred_N PF00732.14 EDN05016.1 - 1.2e-44 152.7 0.0 2.1e-22 79.6 0.0 2.1 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN05016.1 - 5.1e-28 98.1 0.0 1.2e-27 96.9 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EDN05016.1 - 4.4e-05 22.5 0.0 0.04 12.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDN05016.1 - 0.0014 17.6 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EDN05016.1 - 0.0022 16.9 0.0 0.19 10.5 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EDN05016.1 - 0.0031 17.5 0.0 0.0071 16.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDN05016.1 - 0.059 12.4 0.1 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EDN05016.1 - 0.082 11.3 0.0 0.18 10.2 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 EDN05016.1 - 0.2 10.2 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pkinase PF00069.20 EDN05017.1 - 7.9e-10 38.3 0.0 1.7e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EDN05017.1 - 0.014 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.12 EDN05017.1 - 0.047 12.7 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase ARHGEF5_35 PF15441.1 EDN05017.1 - 0.19 10.5 0.1 0.26 10.0 0.1 1.1 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 Pkinase PF00069.20 EDN05018.1 - 5e-65 219.2 0.0 1.5e-64 217.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05018.1 - 9.9e-27 93.6 0.0 1.7e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN05018.1 - 0.0012 17.9 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EDN05018.1 - 0.015 14.6 0.6 0.015 14.6 0.4 1.6 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 EDN05018.1 - 0.02 13.9 0.1 0.036 13.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN05018.1 - 0.16 11.7 4.5 0.18 11.5 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family U79_P34 PF03064.11 EDN05018.1 - 0.81 9.1 8.3 1.4 8.3 5.8 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Sod_Cu PF00080.15 EDN05019.1 - 1.3e-14 54.5 0.0 1.9e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 EDN05019.1 - 5.5e-10 39.2 0.0 8.8e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain TPR_11 PF13414.1 EDN05020.1 - 3.3e-12 45.8 1.6 5.3e-08 32.3 0.0 3.2 1 1 2 3 3 3 2 TPR repeat TPR_2 PF07719.12 EDN05020.1 - 3.3e-12 45.3 5.5 0.00029 20.5 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 EDN05020.1 - 1.3e-11 43.5 5.5 0.00035 20.0 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDN05020.1 - 9.9e-08 31.8 1.0 4.4e-05 23.3 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDN05020.1 - 2.4e-07 30.0 2.0 0.026 14.2 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDN05020.1 - 3e-06 27.3 0.5 9.6 6.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EDN05020.1 - 0.00012 21.8 0.1 0.054 13.3 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDN05020.1 - 0.00012 22.6 1.1 0.0066 17.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDN05020.1 - 0.00013 21.4 0.4 0.0018 17.8 0.1 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat PB1 PF00564.19 EDN05020.1 - 0.00014 21.4 0.1 0.00031 20.3 0.0 1.6 1 0 0 1 1 1 1 PB1 domain TPR_17 PF13431.1 EDN05020.1 - 0.00036 20.5 0.4 0.037 14.2 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN05020.1 - 0.0072 16.8 0.2 0.61 10.8 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.2 EDN05020.1 - 0.046 13.7 0.3 3.3 7.7 0.0 2.9 3 0 0 3 3 3 0 Tetratrico peptide repeat Apc3 PF12895.2 EDN05020.1 - 0.89 9.7 4.2 2.8 8.1 0.1 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Syntaxin-18_N PF10496.4 EDN05021.1 - 2.5e-21 75.2 0.2 1.1e-20 73.2 0.0 2.2 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EDN05021.1 - 0.00017 21.1 2.5 0.00036 20.1 1.1 2.1 2 0 0 2 2 2 1 SNARE domain DUF3819 PF12842.2 EDN05021.1 - 0.011 15.4 0.5 0.011 15.4 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3819) Cluap1 PF10234.4 EDN05021.1 - 0.46 9.6 4.5 0.34 10.0 1.3 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF4588 PF15251.1 EDN05021.1 - 2.4 8.0 7.0 2.5 8.0 3.4 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4588) Acyl_transf_3 PF01757.17 EDN05022.1 - 3.5e-25 88.5 28.6 4.6e-25 88.1 19.8 1.1 1 0 0 1 1 1 1 Acyltransferase family Aminotran_1_2 PF00155.16 EDN05024.1 - 3.8e-81 272.8 0.0 4.3e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-RING_2 PF13639.1 EDN05025.1 - 2.1e-14 53.0 4.5 3.8e-14 52.2 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDN05025.1 - 9.5e-08 31.5 3.4 1.7e-07 30.7 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN05025.1 - 3.5e-07 30.1 5.3 6e-07 29.3 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDN05025.1 - 1.2e-06 28.5 1.2 2.5e-06 27.5 0.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EDN05025.1 - 6.5e-06 25.7 2.1 1.1e-05 25.0 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDN05025.1 - 1.6e-05 24.4 1.8 3e-05 23.5 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDN05025.1 - 0.00029 20.6 1.0 0.00059 19.6 0.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Glypican PF01153.14 EDN05025.1 - 0.003 16.2 3.6 0.0071 15.0 2.5 1.6 1 0 0 1 1 1 1 Glypican zf-RING_4 PF14570.1 EDN05025.1 - 0.0059 16.1 3.1 0.011 15.2 2.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF2615 PF11027.3 EDN05025.1 - 0.046 13.6 1.7 0.13 12.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) zf-RING-like PF08746.6 EDN05025.1 - 0.26 11.3 2.4 0.44 10.5 1.7 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 EDN05025.1 - 0.99 9.4 3.4 13 5.8 2.4 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain Mucin PF01456.12 EDN05025.1 - 2.4 7.9 33.9 0.59 9.9 18.2 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-C3HC4_4 PF15227.1 EDN05025.1 - 3.9 7.4 5.6 7.6 6.5 3.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PBP1_TM PF14812.1 EDN05026.1 - 0.1 12.9 3.2 1.3 9.3 1.5 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3602 PF12223.3 EDN05026.1 - 0.19 12.1 1.7 0.56 10.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3602) MS_channel PF00924.13 EDN05027.1 - 7.1e-20 71.2 1.6 1.6e-19 70.0 1.1 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.1 EDN05027.1 - 0.0017 18.0 0.1 0.021 14.6 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EDN05027.1 - 0.0051 16.0 0.1 0.0051 16.0 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EDN05027.1 - 0.011 15.7 0.3 0.067 13.3 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain pair Mgm101p PF06420.7 EDN05028.1 - 6.8e-93 308.6 0.0 9.3e-93 308.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 MSP1_C PF07462.6 EDN05028.1 - 0.0019 16.6 2.3 0.0024 16.3 1.6 1.1 1 0 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus ORC6 PF05460.8 EDN05028.1 - 8.4 5.3 12.6 18 4.2 8.8 1.5 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) KIAA1328 PF15369.1 EDN05028.1 - 8.5 6.0 7.4 11 5.7 5.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 BPL_N PF09825.4 EDN05029.1 - 1.8e-114 382.3 6.2 2.5e-104 349.0 2.3 3.3 2 1 1 3 3 3 2 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EDN05029.1 - 8.8e-15 54.8 0.0 2.1e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EDN05029.1 - 2.1e-06 27.3 0.0 4.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain NRDE PF05742.7 EDN05030.1 - 1.1e-46 159.4 0.0 5.4e-46 157.0 0.0 1.8 1 1 0 1 1 1 1 NRDE protein MFS_1 PF07690.11 EDN05031.1 - 5.6e-12 45.0 52.1 1.5e-09 37.0 12.4 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EDN05031.1 - 9.4e-08 30.7 22.7 1.3e-07 30.2 15.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TB2_DP1_HVA22 PF03134.14 EDN05032.1 - 5.1e-29 99.8 7.0 8.1e-29 99.2 4.9 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TMF_TATA_bd PF12325.3 EDN05033.1 - 0.054 13.2 1.0 0.13 12.0 0.7 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding SR-25 PF10500.4 EDN05033.1 - 0.22 10.9 10.2 0.36 10.2 7.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein THRAP3_BCLAF1 PF15440.1 EDN05033.1 - 2.4 6.7 14.5 3.2 6.2 10.0 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family PBP_like_2 PF12849.2 EDN05034.1 - 1.5e-10 40.9 0.0 1.9e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 PBP superfamily domain GARS_A PF01071.14 EDN05035.1 - 1.1e-82 276.3 0.0 1.8e-82 275.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EDN05035.1 - 4.6e-36 123.2 0.0 2.8e-35 120.7 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EDN05035.1 - 3.4e-30 105.0 0.1 7.5e-30 103.9 0.1 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EDN05035.1 - 6.5e-26 90.3 0.1 1.7e-25 89.0 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EDN05035.1 - 3.6e-15 55.9 1.7 3.6e-15 55.9 1.1 3.6 2 2 1 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EDN05035.1 - 8.7e-10 38.6 0.0 5.8e-09 35.9 0.0 2.4 3 0 0 3 3 3 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EDN05035.1 - 1.1e-07 30.9 0.0 2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EDN05035.1 - 4.3e-06 26.1 0.0 8.6e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EDN05035.1 - 0.00023 21.0 0.0 0.00054 19.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EDN05035.1 - 0.00091 18.5 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_2 PF08442.5 EDN05035.1 - 0.029 13.7 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EDN05035.1 - 0.078 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF1147 PF06615.6 EDN05035.1 - 0.15 11.8 0.4 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1147) Pet127 PF08634.5 EDN05036.1 - 5.6e-118 393.0 0.0 7.4e-118 392.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet127 PH PF00169.24 EDN05037.1 - 0.0047 17.1 0.0 0.017 15.3 0.0 2.0 1 0 0 1 1 1 1 PH domain LRR_7 PF13504.1 EDN05037.1 - 1.9 9.0 9.9 78 4.1 0.0 6.6 7 1 0 7 7 7 0 Leucine rich repeat Gly_transf_sug PF04488.10 EDN05038.1 - 1.4e-18 67.1 0.1 2.7e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Peptidase_M24 PF00557.19 EDN05040.1 - 8e-41 139.8 0.3 1.2e-40 139.3 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DnaJ PF00226.26 EDN05041.1 - 2.9e-21 74.9 0.1 5.1e-21 74.1 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Bul1_N PF04425.7 EDN05042.1 - 1.9e-10 39.8 2.8 5e-09 35.2 2.0 2.1 1 1 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.7 EDN05042.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Bul1 C terminus Arrestin_N PF00339.24 EDN05042.1 - 0.033 14.0 0.0 0.1 12.3 0.0 1.8 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain DUF605 PF04652.11 EDN05044.1 - 0.23 10.8 17.2 0.27 10.5 11.9 1.2 1 0 0 1 1 1 0 Vta1 like Usp PF00582.21 EDN05045.1 - 1.8e-20 73.6 0.0 4.1e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Universal stress protein family Nucleo_P87 PF07267.6 EDN05045.1 - 1.2 7.7 5.8 1.8 7.1 4.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SNF2_N PF00176.18 EDN05048.1 - 7.2e-72 241.7 0.0 1e-71 241.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN05048.1 - 2.7e-14 52.7 0.0 6.6e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EDN05048.1 - 1.1e-06 27.7 0.0 2.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Pkinase PF00069.20 EDN05049.1 - 2.7e-50 170.9 0.0 6.9e-50 169.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05049.1 - 4.7e-22 78.3 0.1 1e-21 77.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EDN05049.1 - 0.0005 19.8 0.1 0.0005 19.8 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDN05049.1 - 0.0032 16.8 0.2 0.011 15.1 0.1 1.8 1 1 0 1 1 1 1 RIO1 family eIF-3c_N PF05470.7 EDN05050.1 - 5.8e-174 579.5 29.5 6.9e-140 466.9 2.7 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EDN05050.1 - 6.8e-14 52.0 3.8 1.2e-12 48.0 0.0 3.7 3 0 0 3 3 3 1 PCI domain EAP30 PF04157.11 EDN05051.1 - 1.3e-56 191.3 0.0 2.6e-56 190.2 0.0 1.5 1 1 0 1 1 1 1 EAP30/Vps36 family Ribosomal_L30_N PF08079.7 EDN05052.1 - 1e-25 89.5 16.4 1.9e-25 88.6 11.4 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EDN05052.1 - 1.2e-17 63.1 3.5 1.6e-17 62.8 1.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DNA_pol_B PF00136.16 EDN05053.1 - 1.8e-110 369.9 7.3 1.8e-110 369.9 5.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EDN05053.1 - 4.4e-68 228.3 1.5 4.4e-68 228.3 1.0 1.8 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EDN05053.1 - 2.9e-33 115.1 0.0 5.8e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EDN05053.1 - 1.1e-24 85.9 8.0 1.1e-24 85.9 5.6 2.8 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Phos_pyr_kin PF08543.7 EDN05054.1 - 8.4e-85 283.8 4.4 1.1e-84 283.4 3.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EDN05054.1 - 6.1e-47 160.0 0.7 1.3e-31 110.0 0.1 2.2 1 1 1 2 2 2 2 TENA/THI-4/PQQC family PfkB PF00294.19 EDN05054.1 - 5.9e-07 28.9 1.1 1.8e-06 27.3 0.8 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 EDN05054.1 - 0.00069 18.8 1.7 0.013 14.6 0.2 2.4 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family Herpes_ori_bp PF02399.10 EDN05054.1 - 0.15 9.9 0.0 0.21 9.4 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein DEAD PF00270.24 EDN05055.1 - 4.4e-46 156.4 0.0 1.7e-44 151.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN05055.1 - 5.3e-28 96.6 0.0 1.2e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN05055.1 - 0.00015 21.6 0.0 0.00045 20.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EDN05055.1 - 0.0059 16.5 0.0 0.0096 15.8 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 EDN05055.1 - 0.028 12.8 0.0 1.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) DUF2443 PF10398.4 EDN05055.1 - 0.098 12.4 0.2 0.21 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) DUF3723 PF12520.3 EDN05058.1 - 3.3e-109 365.7 5.6 2.3e-82 277.1 0.7 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) RNase_H PF00075.19 EDN05058.1 - 7.6e-17 61.8 0.0 2.4e-16 60.2 0.0 1.8 2 0 0 2 2 2 1 RNase H RVT_3 PF13456.1 EDN05058.1 - 1.4e-05 24.7 0.2 4.3e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase-like Bindin PF02084.10 EDN05058.1 - 0.25 11.3 0.7 5.7 6.9 1.7 2.0 2 0 0 2 2 2 0 Bindin DUF2383 PF09537.5 EDN05059.1 - 0.00058 20.0 0.0 0.00073 19.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) Stork_head PF10264.4 EDN05059.1 - 0.014 15.5 0.0 0.047 13.8 0.0 1.7 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain Ferritin-like PF12902.2 EDN05059.1 - 0.049 13.2 0.1 0.059 12.9 0.1 1.1 1 0 0 1 1 1 0 Ferritin-like ASL_C2 PF14698.1 EDN05059.1 - 0.13 12.3 0.1 0.53 10.3 0.0 1.8 2 0 0 2 2 2 0 Argininosuccinate lyase C-terminal F-box PF00646.28 EDN05060.1 - 1.9e-05 24.1 0.0 4.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN05060.1 - 2.1e-05 24.1 0.0 4.9e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EDN05060.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 PRANC domain Mur_ligase_M PF08245.7 EDN05061.1 - 6.5e-08 32.8 0.0 1.6e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Rad9 PF04139.8 EDN05062.1 - 4.4e-64 216.0 1.4 5.3e-64 215.7 0.9 1.0 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EDN05062.1 - 2.2e-05 23.3 0.5 7.9e-05 21.5 0.4 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 CorA PF01544.13 EDN05062.1 - 0.0049 15.9 0.0 0.009 15.0 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RCC1 PF00415.13 EDN05063.1 - 4.1e-37 126.1 7.4 1.6e-08 34.6 0.0 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDN05063.1 - 1.1e-17 63.1 27.2 1.1e-07 31.2 0.3 6.7 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat PPR_2 PF13041.1 EDN05064.1 - 2.1e-08 34.0 0.0 0.0027 17.6 0.0 3.3 2 1 1 3 3 3 2 PPR repeat family PPR PF01535.15 EDN05064.1 - 0.011 15.6 0.0 14 5.9 0.0 4.1 4 0 0 4 4 4 0 PPR repeat CMV_US PF08001.6 EDN05064.1 - 0.05 12.6 0.0 0.093 11.7 0.0 1.4 1 0 0 1 1 1 0 CMV US NYD-SP28_assoc PF14775.1 EDN05064.1 - 0.35 10.5 1.9 1.9 8.2 0.5 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain Mannitol_dh_C PF08125.8 EDN05065.1 - 3.6e-47 160.6 0.0 5.2e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EDN05065.1 - 7e-22 77.9 0.2 2.9e-21 76.0 0.0 2.0 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 EDN05065.1 - 0.00021 20.6 0.9 0.00034 20.0 0.1 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EDN05065.1 - 0.00072 19.2 0.3 0.01 15.4 0.0 2.6 3 1 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Latarcin PF10279.4 EDN05065.1 - 0.026 14.7 0.0 0.068 13.3 0.0 1.8 2 0 0 2 2 2 0 Latarcin precursor Methyltransf_23 PF13489.1 EDN05065.1 - 0.08 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox PF00070.22 EDN05065.1 - 0.099 13.0 0.5 0.75 10.2 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3439 PF11921.3 EDN05066.1 - 0.73 9.5 4.7 1.6 8.4 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SWIRM PF04433.12 EDN05067.1 - 4e-17 62.1 0.0 1.3e-16 60.5 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 EDN05067.1 - 8.3e-09 34.8 7.3 1.5e-08 34.0 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EDN05067.1 - 4.9e-08 32.8 0.0 1.7e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pkinase PF00069.20 EDN05068.1 - 6.2e-70 235.3 0.0 8.7e-70 234.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05068.1 - 1.4e-32 112.7 0.0 2.1e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EDN05068.1 - 4e-09 36.8 0.1 1.2e-08 35.2 0.0 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EDN05068.1 - 4.8e-05 22.4 0.0 7.4e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF1373 PF07117.6 EDN05068.1 - 0.051 13.2 4.4 0.095 12.4 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) Coatomer_WDAD PF04053.9 EDN05069.1 - 7e-170 565.5 0.0 1.7e-169 564.3 0.0 1.6 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EDN05069.1 - 1.2e-46 155.0 8.1 3.1e-10 39.5 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EDN05069.1 - 0.00014 20.1 1.5 0.037 12.1 0.0 3.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EDN05069.1 - 0.0017 18.1 0.0 2.9 7.7 0.0 3.6 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region ETC_C1_NDUFA5 PF04716.9 EDN05070.1 - 3.1e-23 81.0 0.8 3.1e-23 81.0 0.5 2.6 3 0 0 3 3 3 1 ETC complex I subunit conserved region Chloroplast_duf PF14476.1 EDN05070.1 - 0.13 11.0 1.1 8 5.1 0.0 2.2 1 1 1 2 2 2 0 Petal formation-expressed DUF3416 PF11896.3 EDN05070.1 - 0.29 11.0 3.4 0.66 9.8 0.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3416) DUF4207 PF13904.1 EDN05070.1 - 3.2 7.0 10.1 3.5 6.9 6.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) Thioredoxin PF00085.15 EDN05071.1 - 7.8e-35 118.6 0.0 2.7e-23 81.6 0.0 3.8 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EDN05071.1 - 1.5e-11 44.4 0.0 0.008 15.9 0.0 4.5 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EDN05071.1 - 5.9e-06 26.4 2.7 0.2 11.8 0.1 4.3 4 1 0 4 4 4 2 Thioredoxin-like domain HyaE PF07449.6 EDN05071.1 - 0.00019 21.3 0.0 0.24 11.2 0.0 2.9 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.1 EDN05071.1 - 0.002 18.2 0.3 0.14 12.2 0.1 3.4 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EDN05071.1 - 0.0056 16.6 0.4 0.033 14.1 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EDN05071.1 - 0.038 13.8 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin domain Calsequestrin PF01216.12 EDN05071.1 - 0.069 11.9 0.1 0.14 10.8 0.1 1.4 1 0 0 1 1 1 0 Calsequestrin AA_permease_2 PF13520.1 EDN05072.1 - 1.6e-59 201.5 48.2 2e-59 201.2 33.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN05072.1 - 3e-16 58.8 38.0 4e-16 58.4 26.3 1.1 1 0 0 1 1 1 1 Amino acid permease HTH_29 PF13551.1 EDN05073.1 - 3.5e-06 27.1 0.0 1.4e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EDN05073.1 - 6e-06 25.7 0.2 0.0007 19.1 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EDN05073.1 - 6.3e-06 25.9 0.0 5.1e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_33 PF13592.1 EDN05073.1 - 2.7e-05 23.6 0.0 8e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 EDN05073.1 - 3.4e-05 23.2 0.0 0.00045 19.7 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.1 EDN05073.1 - 0.0011 18.8 0.0 0.1 12.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.13 EDN05073.1 - 0.0083 15.8 0.0 0.014 15.1 0.0 1.4 1 1 0 1 1 1 1 'Paired box' domain HTH_Tnp_IS630 PF01710.11 EDN05073.1 - 0.021 14.4 0.0 0.031 13.9 0.0 1.5 1 1 0 1 1 1 0 Transposase Terminase_5 PF06056.7 EDN05073.1 - 0.051 13.1 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Nucleo_P87 PF07267.6 EDN05074.1 - 0.11 11.1 3.6 0.16 10.6 2.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DDE_1 PF03184.14 EDN05075.1 - 4.9e-19 68.3 0.0 2.3e-16 59.6 0.0 2.8 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN05075.1 - 0.02 14.7 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DUF3760 PF12586.3 EDN05076.1 - 0.027 14.3 0.0 7 6.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3760) Cortex-I_coil PF09304.5 EDN05076.1 - 0.11 12.5 0.2 0.21 11.6 0.0 1.5 2 0 0 2 2 2 0 Cortexillin I, coiled coil ACBP PF00887.14 EDN05077.1 - 4.9e-25 87.0 0.1 5.6e-25 86.8 0.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein U-box PF04564.10 EDN05078.1 - 1.8e-23 82.2 0.1 3.4e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 EDN05078.1 - 2.1e-17 62.5 3.0 1.1e-16 60.1 0.0 2.7 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EDN05078.1 - 2.6e-09 36.2 2.9 0.0015 18.3 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EDN05078.1 - 3.6e-07 29.5 3.5 4.4e-05 22.8 0.1 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN05078.1 - 8.9e-07 29.4 6.4 7.2e-05 23.3 0.0 2.6 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDN05078.1 - 9.4e-06 25.4 0.9 0.00011 22.1 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN05078.1 - 9.1e-05 22.7 0.1 0.0013 19.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN05078.1 - 0.00012 22.4 3.1 0.06 14.0 0.0 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat GvpG PF05120.7 EDN05078.1 - 0.013 15.2 1.6 0.034 13.9 1.1 1.7 1 0 0 1 1 1 0 Gas vesicle protein G TPR_9 PF13371.1 EDN05078.1 - 0.031 14.1 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EDN05078.1 - 0.036 14.2 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 CALCOCO1 PF07888.6 EDN05078.1 - 0.079 11.2 0.7 0.098 10.9 0.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like zf-Nse PF11789.3 EDN05078.1 - 0.14 11.7 0.1 0.4 10.2 0.0 1.7 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EDN05078.1 - 0.14 11.8 0.0 0.42 10.3 0.0 1.8 1 1 0 1 1 1 0 RING-type zinc-finger TPR_12 PF13424.1 EDN05078.1 - 0.4 10.6 5.3 0.48 10.3 0.2 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat DDE_Tnp_4 PF13359.1 EDN05080.1 - 1.6e-09 37.5 0.0 2.8e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EDN05080.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_7 PF13843.1 EDN05081.1 - 8.5e-35 120.4 0.0 1e-34 120.1 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 PIF1 PF05970.9 EDN05083.1 - 2.7e-22 79.2 0.0 5.1e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 EDN05083.1 - 0.022 14.4 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain UvrD_C_2 PF13538.1 EDN05083.1 - 0.065 13.3 0.6 0.33 11.1 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain GAGA_bind PF06217.7 EDN05083.1 - 0.83 9.5 21.5 1.4 8.8 14.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Macoilin PF09726.4 EDN05083.1 - 9 4.4 30.5 15 3.6 21.1 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF3435 PF11917.3 EDN05085.1 - 1.8e-29 102.7 4.9 9.2e-17 60.8 0.4 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3435) AA_permease_N PF08403.5 EDN05085.1 - 0.016 14.4 0.4 0.016 14.4 0.3 2.1 2 0 0 2 2 2 0 Amino acid permease N-terminal DUF371 PF04027.8 EDN05085.1 - 0.037 13.6 0.0 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF371) DHO_dh PF01180.16 EDN05086.1 - 5.6e-61 206.0 0.3 5.4e-52 176.5 0.0 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 EDN05086.1 - 7.9e-07 28.5 1.2 0.0074 15.5 0.0 2.8 3 0 0 3 3 3 2 PcrB family DUF694 PF05107.7 EDN05086.1 - 0.00062 19.0 0.1 0.00095 18.4 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF694) FMN_dh PF01070.13 EDN05086.1 - 0.058 12.2 0.7 0.11 11.3 0.0 1.8 3 0 0 3 3 3 0 FMN-dependent dehydrogenase Lyase_catalyt PF09093.6 EDN05088.1 - 0.022 13.6 0.0 0.026 13.4 0.0 1.1 1 0 0 1 1 1 0 Lyase, catalytic SprA-related PF12118.3 EDN05090.1 - 1.4 8.1 12.3 1.7 7.9 8.6 1.1 1 0 0 1 1 1 0 SprA-related family DUF4661 PF15576.1 EDN05090.1 - 1.4 8.4 4.7 1.6 8.3 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF2201_N PF13203.1 EDN05090.1 - 1.5 7.8 7.1 1.9 7.6 4.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 EDN05090.1 - 2.9 5.8 14.2 3.6 5.4 9.8 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 EDN05090.1 - 3.2 5.7 6.6 3.2 5.7 4.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_C37 PF05416.7 EDN05090.1 - 3.5 5.8 10.6 5 5.2 7.3 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase ATP-synt_E PF05680.7 EDN05090.1 - 4.9 7.1 16.4 17 5.4 7.5 2.4 2 0 0 2 2 2 0 ATP synthase E chain TRAP_alpha PF03896.11 EDN05090.1 - 5.5 5.8 7.6 6.1 5.7 5.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SspB PF04386.8 EDN05090.1 - 7 6.2 8.3 11 5.5 5.8 1.4 1 0 0 1 1 1 0 Stringent starvation protein B AAA PF00004.24 EDN05091.1 - 1.5e-10 41.3 0.0 2.1e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-H2C2_2 PF13465.1 EDN05095.1 - 3e-06 27.2 13.6 6.6e-05 23.0 1.7 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDN05095.1 - 8.8e-06 25.6 14.8 0.00019 21.5 4.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EDN05095.1 - 0.0013 18.7 4.9 0.0025 17.9 3.4 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EDN05095.1 - 0.011 15.9 18.1 0.018 15.3 4.6 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EDN05095.1 - 0.057 13.5 1.0 0.057 13.5 0.7 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EDN05095.1 - 0.87 9.3 7.9 0.24 11.1 0.7 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.1 EDN05095.1 - 7.1 6.4 9.7 8.7 6.1 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type OmpH PF03938.9 EDN05096.1 - 0.00091 19.1 7.4 0.0017 18.2 5.1 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Choline_kinase PF01633.15 EDN05096.1 - 0.013 15.1 0.0 0.032 13.8 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EDN05096.1 - 0.033 13.9 0.2 0.033 13.9 0.2 3.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 EDN05096.1 - 0.042 13.1 0.0 0.042 13.1 0.0 1.7 2 0 0 2 2 2 0 RIO1 family HAUS6_N PF14661.1 EDN05096.1 - 4.5 6.5 15.6 8.2 5.7 10.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Atg14 PF10186.4 EDN05096.1 - 9.7 5.0 16.3 20 3.9 11.3 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 EST1_DNA_bind PF10373.4 EDN05099.1 - 0.00061 19.0 0.0 0.0012 18.1 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Macoilin PF09726.4 EDN05101.1 - 0.073 11.3 5.7 0.083 11.1 3.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Prp19 PF08606.6 EDN05101.1 - 0.097 12.4 2.0 0.24 11.1 1.4 1.7 1 0 0 1 1 1 0 Prp19/Pso4-like Fib_alpha PF08702.5 EDN05101.1 - 0.78 9.8 7.1 5.6 7.0 0.5 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4404 PF14357.1 EDN05101.1 - 5.9 7.3 13.8 16 5.9 0.5 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) Patatin PF01734.17 EDN05103.1 - 3.4e-17 63.0 0.2 8.7e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase zf-RING_5 PF14634.1 EDN05103.1 - 0.0094 15.6 7.5 0.0094 15.6 5.2 2.6 2 1 0 2 2 2 1 zinc-RING finger domain Cys_rich_CPXG PF14255.1 EDN05103.1 - 0.015 15.0 0.8 0.28 11.0 0.1 2.4 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-C3HC4_2 PF13923.1 EDN05103.1 - 0.016 15.2 10.1 0.067 13.2 6.3 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EDN05103.1 - 0.039 13.4 8.5 0.3 10.6 5.9 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 EDN05103.1 - 0.055 13.3 8.5 0.19 11.5 5.9 2.1 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 EDN05103.1 - 0.067 12.8 4.2 0.3 10.7 2.9 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN05103.1 - 0.61 9.8 13.7 0.02 14.5 4.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EDN05103.1 - 8.9 6.1 12.9 2.7 7.8 5.6 2.7 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Atg14 PF10186.4 EDN05104.1 - 8.1 5.2 10.3 10 4.9 7.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3723 PF12520.3 EDN05105.1 - 3.5e-148 494.2 0.0 4e-148 494.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) LGFP PF08310.6 EDN05105.1 - 0.086 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 LGFP repeat Pkinase PF00069.20 EDN05106.1 - 1.8e-10 40.4 0.1 2.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05106.1 - 1e-09 37.8 0.1 1.6e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_8 PF08022.7 EDN05108.1 - 1.3e-07 31.4 0.0 6.6e-07 29.1 0.0 2.1 3 0 0 3 3 3 1 FAD-binding domain NAD_binding_6 PF08030.7 EDN05108.1 - 6.7e-07 29.3 0.0 8.4e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF2505 PF10698.4 EDN05109.1 - 0.064 12.7 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) MFS_3 PF05977.8 EDN05110.1 - 0.22 9.6 0.2 0.31 9.1 0.1 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector DUF3435 PF11917.3 EDN05111.1 - 2.4e-171 570.0 0.5 3.9e-171 569.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Meckelin PF09773.4 EDN05111.1 - 0.16 9.6 0.1 0.32 8.7 0.0 1.4 2 0 0 2 2 2 0 Meckelin (Transmembrane protein 67) Tower PF09121.5 EDN05112.1 - 0.061 13.2 0.3 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 Tower NQRA_SLBB PF11973.3 EDN05112.1 - 0.072 13.4 0.0 0.2 12.0 0.0 1.7 2 0 0 2 2 2 0 NQRA C-terminal domain Usp PF00582.21 EDN05112.1 - 0.14 12.3 2.0 0.24 11.6 1.4 1.4 1 0 0 1 1 1 0 Universal stress protein family rve PF00665.21 EDN05113.1 - 3.5e-16 59.4 0.0 5.6e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EDN05113.1 - 8.3e-09 34.9 0.1 1.9e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag_pre-integrs PF13976.1 EDN05113.1 - 0.04 13.5 0.1 0.079 12.6 0.1 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain Y_phosphatase PF00102.22 EDN05114.1 - 6.9e-42 143.3 0.0 1e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EDN05114.1 - 0.00017 21.6 0.0 0.00037 20.5 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EDN05114.1 - 0.0071 15.9 0.5 0.02 14.4 0.0 2.1 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EDN05114.1 - 0.042 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family TraG-D_C PF12696.2 EDN05114.1 - 9.5 6.1 8.0 1.3 8.8 0.0 2.9 3 1 0 3 3 3 0 TraM recognition site of TraD and TraG VanZ PF04892.7 EDN05115.1 - 3.8e-12 46.2 0.1 4.9e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 VanZ like family Bromodomain PF00439.20 EDN05116.1 - 6.6e-22 77.2 2.0 3.3e-20 71.7 0.2 2.8 2 0 0 2 2 2 2 Bromodomain Bromo_TP PF07524.8 EDN05116.1 - 7.8e-07 28.7 0.0 2.5e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 Bromodomain associated APH PF01636.18 EDN05117.1 - 1.2e-07 31.6 0.1 3.1e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Lgl_C PF08596.5 EDN05118.1 - 1.1e-41 142.6 0.0 3.2e-41 141.1 0.0 1.7 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EDN05118.1 - 0.00038 20.2 2.9 0.11 12.4 0.1 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat ASF1_hist_chap PF04729.8 EDN05119.1 - 3.6e-39 133.8 0.4 5.8e-21 74.7 0.1 2.3 1 1 1 2 2 2 2 ASF1 like histone chaperone Nop14 PF04147.7 EDN05119.1 - 2.3 6.0 28.7 3.1 5.6 19.9 1.2 1 0 0 1 1 1 0 Nop14-like family Suf PF05843.9 EDN05120.1 - 4.3e-53 180.8 10.2 2.8e-38 132.2 0.0 4.7 4 2 2 6 6 6 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EDN05120.1 - 0.00033 21.0 0.1 0.22 12.2 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDN05120.1 - 0.00082 19.9 0.1 0.0058 17.2 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat HAT PF02184.11 EDN05120.1 - 0.0075 15.9 0.1 0.0075 15.9 0.1 3.0 4 0 0 4 4 4 1 HAT (Half-A-TPR) repeat Piwi PF02171.12 EDN05121.1 - 4.4e-72 242.6 0.0 6.1e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EDN05121.1 - 1.4e-17 62.8 0.1 3.7e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EDN05121.1 - 8.5e-13 47.7 0.1 1.6e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain TPP_enzyme_N PF02776.13 EDN05123.1 - 2.2e-28 98.9 0.1 3.7e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDN05123.1 - 6.1e-23 81.0 0.0 1.8e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EDN05123.1 - 3.8e-16 59.0 0.0 8.8e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EDN05123.1 - 0.003 16.3 0.0 0.005 15.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Fungal_trans PF04082.13 EDN05124.1 - 2.2e-32 111.9 0.1 4.5e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN05124.1 - 2.6e-11 43.2 12.6 4.2e-11 42.5 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EDN05124.1 - 0.079 12.9 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Gal4-like dimerisation domain Methyltransf_23 PF13489.1 EDN05125.1 - 0.0017 18.1 0.0 0.31 10.7 0.1 2.3 1 1 1 2 2 2 2 Methyltransferase domain Sugar_tr PF00083.19 EDN05126.1 - 5.5e-38 130.6 11.3 8e-38 130.1 7.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN05126.1 - 4.3e-13 48.7 17.2 7.1e-13 47.9 11.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF791 PF05631.9 EDN05126.1 - 0.015 14.0 2.3 0.024 13.3 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF791) TRI12 PF06609.8 EDN05126.1 - 0.035 12.3 2.4 0.048 11.8 1.7 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Phage_holin_5 PF06946.6 EDN05126.1 - 4.5 7.5 6.1 3.9 7.6 2.7 2.0 1 1 0 2 2 2 0 Phage holin Sugar_tr PF00083.19 EDN05127.1 - 1.2e-19 70.2 6.4 1.2e-19 70.2 4.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Collagen PF01391.13 EDN05128.1 - 0.19 11.3 1.8 0.3 10.6 1.3 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF3712 PF12505.3 EDN05129.1 - 1.3e-12 47.8 0.0 4.8e-10 39.5 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF3712) Fungal_trans_2 PF11951.3 EDN05130.1 - 4.8e-06 25.4 0.1 1e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sigma70_r2 PF04542.9 EDN05130.1 - 0.01 15.4 0.0 0.033 13.8 0.0 1.8 1 0 0 1 1 1 0 Sigma-70 region 2 PHD PF00628.24 EDN05131.1 - 3.3e-09 36.3 2.8 7.2e-09 35.2 2.0 1.5 1 0 0 1 1 1 1 PHD-finger MSA-2c PF12238.3 EDN05133.1 - 0.094 12.3 1.6 3.9 7.0 0.3 2.2 2 0 0 2 2 2 0 Merozoite surface antigen 2c Aldolase_II PF00596.16 EDN05134.1 - 5.4e-44 149.9 0.9 6.8e-44 149.6 0.6 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF4160 PF13711.1 EDN05134.1 - 0.06 13.1 0.3 5.5 6.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4160) Med31 PF05669.7 EDN05136.1 - 5.6e-29 99.9 0.0 7.6e-29 99.4 0.0 1.1 1 0 0 1 1 1 1 SOH1 Nic96 PF04097.9 EDN05136.1 - 0.11 10.5 0.0 0.13 10.4 0.0 1.0 1 0 0 1 1 1 0 Nup93/Nic96 Tcf25 PF04910.9 EDN05136.1 - 0.11 11.3 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Transcriptional repressor TCF25 Pal1 PF08316.6 EDN05138.1 - 1.3e-49 168.2 0.6 1.3e-49 168.2 0.4 2.9 3 1 0 3 3 3 1 Pal1 cell morphology protein Xan_ur_permease PF00860.15 EDN05139.1 - 4.4e-16 58.3 31.9 5.5e-08 31.6 8.3 3.5 2 1 0 2 2 2 2 Permease family MAGE PF01454.14 EDN05140.1 - 2.8e-40 137.7 0.0 3.6e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 MAGE family Ank_2 PF12796.2 EDN05141.1 - 9.9e-10 38.6 0.1 3.5e-08 33.6 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDN05141.1 - 1.4e-08 34.6 0.2 0.13 12.5 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN05141.1 - 4.2e-08 32.6 0.5 0.011 15.9 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EDN05141.1 - 6.2e-07 29.7 0.1 0.018 15.5 0.0 3.4 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EDN05141.1 - 6.4e-06 25.7 0.8 0.035 13.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat PPR_3 PF13812.1 EDN05141.1 - 0.15 12.3 0.2 51 4.5 0.0 3.2 3 0 0 3 3 3 0 Pentatricopeptide repeat domain RNA_POL_M_15KD PF02150.11 EDN05142.1 - 8.7e-06 25.3 2.4 3.2e-05 23.5 1.6 1.9 1 1 0 1 1 1 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EDN05142.1 - 0.11 12.3 0.5 0.17 11.6 0.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain GTP_EFTU PF00009.22 EDN05143.1 - 3.8e-57 192.7 0.0 6e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDN05143.1 - 6.8e-37 125.6 0.0 1.9e-36 124.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDN05143.1 - 3.1e-16 59.2 1.8 6.2e-16 58.2 0.7 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EDN05143.1 - 1.2e-05 24.8 0.2 3.7e-05 23.2 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EDN05143.1 - 0.0035 17.2 0.2 0.0097 15.8 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EDN05143.1 - 0.065 12.7 0.5 6.5 6.3 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF3210 PF11489.3 EDN05144.1 - 1.6e-245 817.2 67.8 1.6e-245 817.2 47.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3210) DUF1765 PF08578.5 EDN05145.1 - 5.7e-44 149.1 4.7 1.4e-43 147.9 3.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) ATP_sub_h PF10775.4 EDN05146.1 - 1.9e-25 88.3 2.2 2.8e-25 87.8 1.5 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h TFIIB PF00382.14 EDN05148.1 - 1.9e-39 133.3 0.1 1.2e-20 73.0 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EDN05148.1 - 6.7e-11 41.3 0.6 6.7e-11 41.3 0.4 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding DZR PF12773.2 EDN05148.1 - 0.12 12.1 1.1 0.62 9.9 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon Rubredoxin PF00301.15 EDN05148.1 - 0.77 9.6 5.4 1.2 9.0 0.1 2.8 3 0 0 3 3 3 0 Rubredoxin TFR_dimer PF04253.10 EDN05149.1 - 8.1e-30 102.9 0.1 1.3e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EDN05149.1 - 1.1e-13 51.2 0.0 2.2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EDN05149.1 - 6.9e-09 35.3 0.0 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 PA domain HMG_CoA_synt_C PF08540.5 EDN05150.1 - 3e-99 332.0 1.7 3.4e-97 325.3 1.1 2.1 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EDN05150.1 - 5.9e-96 318.9 0.1 1e-95 318.2 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal GFO_IDH_MocA PF01408.17 EDN05152.1 - 5.2e-11 43.1 0.1 1.9e-10 41.3 0.1 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EDN05152.1 - 0.02 14.7 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain PGM_PMM_I PF02878.11 EDN05153.1 - 3.3e-33 114.0 0.0 4.8e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EDN05153.1 - 2.2e-24 85.6 0.0 4.3e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EDN05153.1 - 3.1e-16 59.6 0.1 7.8e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EDN05153.1 - 1.6e-09 37.6 0.1 3.4e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.19 EDN05154.1 - 1.3e-24 87.3 0.0 1.5e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Exonuclease RVT_1 PF00078.22 EDN05156.1 - 6.6e-29 100.7 0.0 8.9e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3505 PF12013.3 EDN05158.1 - 2.6 8.3 5.1 0.84 9.8 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3505) CLPTM1 PF05602.7 EDN05159.1 - 0.097 11.3 0.1 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) PB1-F2 PF11986.3 EDN05160.1 - 0.084 12.9 1.7 0.18 11.8 1.2 1.6 1 0 0 1 1 1 0 Influenza A Proapoptotic protein DUF327 PF03885.8 EDN05160.1 - 0.15 11.8 3.5 2.4 7.9 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF327) HWE_HK PF07536.9 EDN05160.1 - 0.23 11.9 2.1 0.54 10.7 0.8 2.1 1 1 1 2 2 2 0 HWE histidine kinase DUF2267 PF10025.4 EDN05160.1 - 0.27 11.3 3.8 0.4 10.7 1.7 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) V_ATPase_I PF01496.14 EDN05160.1 - 0.32 8.8 2.6 0.39 8.5 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1779 PF08680.5 EDN05160.1 - 0.33 10.7 4.1 0.47 10.2 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) HalX PF08663.5 EDN05160.1 - 0.36 10.8 7.5 0.38 10.7 1.2 3.1 2 1 1 3 3 3 0 HalX domain DUF16 PF01519.11 EDN05160.1 - 0.93 9.7 5.1 3.7 7.8 3.6 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 Salp15 PF12115.3 EDN05160.1 - 3.5 7.8 6.2 90 3.3 4.3 2.3 1 1 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation DUF624 PF04854.9 EDN05161.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF624 Rep-A_N PF04057.7 EDN05161.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain Tenui_PVC2 PF06656.6 EDN05162.1 - 0.087 10.6 0.0 0.1 10.3 0.0 1.0 1 0 0 1 1 1 0 Tenuivirus PVC2 protein CAP59_mtransfer PF11735.3 EDN05163.1 - 3.8e-88 294.7 0.0 5.7e-88 294.2 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Suc_Fer-like PF06999.7 EDN05164.1 - 2.6e-38 132.3 0.1 1.8e-37 129.6 0.1 2.0 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Opiods_neuropep PF01160.13 EDN05164.1 - 0.17 11.6 1.5 0.41 10.4 1.0 1.7 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide Fungal_trans PF04082.13 EDN05165.1 - 3.5e-18 65.4 1.9 3.5e-18 65.4 1.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN05165.1 - 5.5e-07 29.3 5.4 1.3e-06 28.2 3.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAF1_ABF1 PF04684.8 EDN05165.1 - 2.9 6.6 6.6 4.5 6.0 4.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor adh_short PF00106.20 EDN05166.1 - 6.2e-19 68.5 6.7 6e-18 65.3 4.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN05166.1 - 4.2e-18 65.9 1.6 2.8e-17 63.2 1.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN05166.1 - 1.3e-06 28.2 3.6 1.2e-05 25.0 0.8 2.1 2 0 0 2 2 2 1 KR domain HHH_5 PF14520.1 EDN05166.1 - 0.1 12.7 0.4 0.39 10.9 0.3 2.1 1 1 0 1 1 1 0 Helix-hairpin-helix domain SMC_N PF02463.14 EDN05168.1 - 2.7e-78 262.2 0.0 6e-78 261.0 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDN05168.1 - 2.1e-28 98.6 0.1 1.1e-27 96.3 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EDN05168.1 - 1.3e-11 45.0 8.3 1.7e-05 24.9 0.8 3.3 2 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EDN05168.1 - 0.00055 19.4 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CRCB PF02537.10 EDN05168.1 - 0.26 11.1 0.0 0.49 10.2 0.0 1.3 1 0 0 1 1 1 0 CrcB-like protein Reo_sigmaC PF04582.7 EDN05168.1 - 0.51 9.4 24.7 3.5 6.6 0.4 4.8 2 1 2 4 4 4 0 Reovirus sigma C capsid protein ELYS PF13934.1 EDN05169.1 - 1.6e-77 260.2 0.5 2e-77 259.9 0.4 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly zf-CCCH PF00642.19 EDN05170.1 - 6.1e-05 22.5 1.7 0.00012 21.6 1.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_S10 PF00338.17 EDN05171.1 - 1.4e-27 95.3 0.6 1.7e-27 95.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.11 EDN05172.1 - 4.7e-10 38.7 0.0 8.2e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 CUE domain FA_desaturase PF00487.19 EDN05173.1 - 2.3e-35 122.2 30.5 3.3e-35 121.7 21.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EDN05173.1 - 4.1e-10 39.3 0.0 8.4e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PGM_PMM_II PF02879.11 EDN05174.1 - 2.8e-25 88.6 0.0 6.4e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_I PF02878.11 EDN05174.1 - 1.8e-24 85.7 0.0 3.2e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EDN05174.1 - 6.1e-13 48.8 0.0 1.3e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EDN05174.1 - 2.1e-10 40.4 0.0 5.3e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pyr_redox_2 PF07992.9 EDN05175.1 - 8.7e-40 136.7 13.0 1.4e-37 129.5 9.0 4.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EDN05175.1 - 9.2e-40 135.0 0.4 3.3e-39 133.3 0.3 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EDN05175.1 - 9.6e-22 77.1 12.0 7.1e-20 71.2 0.9 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDN05175.1 - 7.4e-11 41.7 8.3 2.2e-10 40.2 0.1 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 EDN05175.1 - 1.3e-10 40.7 10.0 8.3e-09 34.7 2.2 2.7 2 1 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EDN05175.1 - 5.5e-10 39.6 2.1 5.1e-07 29.9 0.1 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN05175.1 - 2.2e-09 37.2 5.7 5.1e-05 23.2 0.4 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDN05175.1 - 2.1e-08 33.4 11.1 5.4e-08 32.0 2.1 2.5 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EDN05175.1 - 5.8e-08 32.0 16.7 0.00016 20.6 1.1 3.7 3 1 1 4 4 4 3 FAD dependent oxidoreductase HI0933_like PF03486.9 EDN05175.1 - 1.2e-06 27.3 15.8 6.5e-05 21.5 1.4 3.9 4 0 0 4 4 4 3 HI0933-like protein K_oxygenase PF13434.1 EDN05175.1 - 1.2e-06 27.7 0.7 0.037 12.9 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EDN05175.1 - 2.6e-06 27.0 5.2 0.0016 18.0 0.2 3.1 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EDN05175.1 - 0.0001 21.4 1.8 0.0001 21.4 1.2 2.6 1 1 1 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EDN05175.1 - 0.0022 17.1 11.9 0.011 14.7 1.0 3.0 3 1 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.7 EDN05175.1 - 0.0022 16.9 1.3 0.056 12.3 0.0 2.5 2 0 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.19 EDN05175.1 - 0.025 13.6 0.3 0.17 10.9 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 EDN05175.1 - 0.11 12.7 6.6 0.39 10.9 0.1 3.1 3 1 0 3 3 3 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EDN05175.1 - 0.13 11.9 8.4 0.052 13.1 0.6 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.14 EDN05175.1 - 0.28 9.3 3.7 0.2 9.8 0.6 1.9 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.9 EDN05175.1 - 0.3 9.6 7.2 0.3 9.6 0.5 2.3 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 EDN05175.1 - 2.2 7.6 6.5 1.6 8.0 0.3 2.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RNase_T PF00929.19 EDN05177.1 - 2e-10 41.2 0.2 5.4e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 Exonuclease CHORD PF04968.7 EDN05177.1 - 0.00013 22.1 2.1 0.00029 21.0 1.5 1.6 1 0 0 1 1 1 1 CHORD DUF2072 PF09845.4 EDN05177.1 - 5.9 6.8 10.3 0.17 11.8 1.9 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) Sugar_tr PF00083.19 EDN05179.1 - 8.4e-30 103.7 32.9 6.5e-18 64.5 8.8 3.3 2 2 2 4 4 4 3 Sugar (and other) transporter MFS_1 PF07690.11 EDN05179.1 - 2.1e-14 53.0 37.6 5.2e-12 45.1 9.7 2.6 3 0 0 3 3 3 2 Major Facilitator Superfamily Myc_N PF01056.13 EDN05180.1 - 0.044 12.9 4.4 0.15 11.1 3.0 1.7 2 0 0 2 2 2 0 Myc amino-terminal region ATP-sulfurylase PF01747.12 EDN05180.1 - 0.14 11.3 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 ATP-sulfurylase Pox_RNA_Pol_19 PF05320.7 EDN05180.1 - 0.18 11.5 5.0 10 5.8 3.4 2.2 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Nucleoplasmin PF03066.10 EDN05180.1 - 0.58 9.6 6.8 0.91 9.0 4.2 1.6 2 0 0 2 2 2 0 Nucleoplasmin BSP_II PF05432.6 EDN05180.1 - 1.1 8.5 10.5 1.5 7.9 7.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FmdA_AmdA PF03069.10 EDN05181.1 - 5.9e-150 499.0 0.0 6.7e-150 498.8 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family FAD_binding_4 PF01565.18 EDN05182.1 - 1.2e-19 70.1 4.0 3e-19 68.8 2.7 1.7 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDN05182.1 - 1.2e-09 37.9 1.6 3.5e-09 36.4 0.6 2.1 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 EDN05182.1 - 0.077 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Pro_isomerase PF00160.16 EDN05183.1 - 1.5e-26 93.4 0.1 2.4e-26 92.8 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EDN05183.1 - 3.1e-09 36.3 8.0 0.00045 19.8 0.3 2.3 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EDN05183.1 - 2.5e-05 23.8 9.9 6.5e-05 22.5 2.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDN05183.1 - 0.00019 20.8 5.7 0.00022 20.7 0.7 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDN05183.1 - 0.00046 20.0 8.9 0.0021 17.9 4.5 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDN05183.1 - 0.01 16.4 13.1 0.22 12.2 6.5 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDN05183.1 - 0.016 14.9 0.7 0.016 14.9 0.5 2.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDN05183.1 - 0.04 14.5 5.3 0.19 12.4 1.7 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EDN05183.1 - 0.11 12.3 2.7 0.52 10.2 0.9 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDN05183.1 - 0.77 10.3 4.8 0.92 10.1 0.5 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat DSBA PF01323.15 EDN05183.1 - 2.3 7.7 6.0 1.2 8.6 1.9 1.9 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Tyr_Deacylase PF02580.11 EDN05184.1 - 7.3e-48 162.2 0.1 8.4e-48 162.0 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.10 EDN05185.1 - 2.4e-97 324.8 15.2 3.6e-97 324.2 10.6 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EDN05185.1 - 1.6e-42 144.5 11.6 4.3e-42 143.1 8.0 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Poty_PP PF08440.5 EDN05185.1 - 0.0042 16.1 0.9 0.008 15.2 0.6 1.4 1 0 0 1 1 1 1 Potyviridae polyprotein DUF2373 PF10180.4 EDN05185.1 - 0.013 14.9 3.5 0.028 13.9 2.4 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Syntaxin_2 PF14523.1 EDN05185.1 - 0.043 13.8 2.8 0.15 12.1 2.0 2.0 1 0 0 1 1 1 0 Syntaxin-like protein Cep57_MT_bd PF06657.8 EDN05185.1 - 0.068 13.1 0.3 0.068 13.1 0.2 2.9 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF2951 PF11166.3 EDN05185.1 - 3.9 7.4 6.8 0.95 9.3 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) zf-C2H2_4 PF13894.1 EDN05187.1 - 1.5e-05 24.9 6.6 0.025 14.8 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN05187.1 - 0.00044 20.4 7.1 0.2 12.0 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type CCDC14 PF15254.1 EDN05187.1 - 2.6 6.3 7.2 3.7 5.8 5.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 DNA_binding_1 PF01035.15 EDN05188.1 - 8e-25 86.4 0.0 1.1e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Pkinase PF00069.20 EDN05189.1 - 2.4e-23 82.6 0.0 2.8e-18 66.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05189.1 - 0.0051 15.9 0.0 0.014 14.4 0.0 1.7 2 1 0 2 2 2 1 Protein tyrosine kinase UPF0546 PF10639.4 EDN05190.1 - 5.2e-37 126.1 1.1 1.6e-36 124.5 0.8 1.7 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 DUF1211 PF06736.6 EDN05190.1 - 0.036 14.2 0.0 0.088 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) DUF3299 PF11736.3 EDN05190.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) EamA PF00892.15 EDN05190.1 - 0.17 11.9 5.8 0.12 12.3 2.1 2.0 2 0 0 2 2 2 0 EamA-like transporter family EmrE PF13536.1 EDN05190.1 - 0.45 10.7 6.6 0.051 13.7 1.6 1.7 2 0 0 2 2 2 0 Multidrug resistance efflux transporter Pkinase PF00069.20 EDN05191.1 - 1.6e-07 30.7 0.0 1.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EDN05191.1 - 0.0014 17.7 0.3 0.002 17.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN05191.1 - 0.0035 17.1 0.8 0.0045 16.7 0.6 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Deltaretro_Tax PF05599.6 EDN05191.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 Deltaretrovirus Tax protein Chitin_synth_1 PF01644.12 EDN05192.1 - 3e-81 271.0 0.1 4.3e-81 270.4 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EDN05192.1 - 3.5e-31 106.7 0.0 6.9e-31 105.7 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EDN05192.1 - 1e-21 76.9 2.7 1.5e-17 63.1 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EDN05192.1 - 1.9e-09 37.5 5.6 1.9e-09 37.5 3.9 3.1 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDN05192.1 - 3.2e-08 33.6 0.0 1.8e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF4190 PF13828.1 EDN05192.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) LMWPc PF01451.16 EDN05193.1 - 1.8e-32 112.5 0.0 4.4e-30 104.8 0.0 2.2 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase COQ7 PF03232.8 EDN05194.1 - 7.5e-62 207.8 0.0 1.1e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EDN05194.1 - 0.0024 18.2 0.1 0.0053 17.0 0.0 1.6 1 1 0 1 1 1 1 Rubrerythrin Plus-3 PF03126.13 EDN05195.1 - 1.9e-34 117.9 0.6 2.6e-33 114.3 0.0 2.6 3 0 0 3 3 3 1 Plus-3 domain MRC1 PF09444.5 EDN05196.1 - 1.5e-22 80.5 22.1 7e-19 68.5 4.9 8.6 6 3 2 8 8 8 2 MRC1-like domain PqqD PF05402.7 EDN05197.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) MIF4G PF02854.14 EDN05198.1 - 1.2e-22 80.3 1.2 2.9e-22 79.1 0.2 2.1 3 0 0 3 3 3 1 MIF4G domain MA3 PF02847.12 EDN05198.1 - 2.1e-17 62.8 0.0 9.3e-17 60.7 0.0 2.2 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.10 EDN05199.1 - 5.9e-22 77.3 0.0 8.7e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein EI24 PF07264.6 EDN05201.1 - 7.1e-08 32.1 7.8 1.1e-07 31.5 5.4 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4112 PF13430.1 EDN05201.1 - 0.4 10.6 2.3 8.8 6.2 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4112) DUF3487 PF11990.3 EDN05201.1 - 0.46 9.8 3.5 11 5.3 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3487) F-box PF00646.28 EDN05202.1 - 0.0012 18.4 0.5 0.0034 16.9 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN05202.1 - 0.0014 18.3 0.5 0.0028 17.3 0.4 1.6 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EDN05202.1 - 0.0048 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 PRANC domain SLT PF01464.15 EDN05204.1 - 0.0057 16.1 0.1 0.024 14.1 0.0 1.9 2 0 0 2 2 2 1 Transglycosylase SLT domain Lysozyme_like PF13702.1 EDN05204.1 - 0.025 14.0 0.0 2.3 7.6 0.0 2.1 2 0 0 2 2 2 0 Lysozyme-like NAGidase PF07555.8 EDN05205.1 - 1.2e-106 356.0 0.1 2.6e-106 355.0 0.2 1.4 2 0 0 2 2 2 1 beta-N-acetylglucosaminidase Glyco_hydro_20b PF02838.10 EDN05205.1 - 6.2e-12 46.1 0.0 1.8e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_67N PF03648.9 EDN05205.1 - 0.0001 22.3 0.0 0.00025 21.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Abhydrolase_6 PF12697.2 EDN05207.1 - 1.5e-18 67.5 0.6 3.1e-18 66.5 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN05207.1 - 6.2e-06 26.0 0.1 1e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family BenE PF03594.8 EDN05210.1 - 0.00036 19.1 12.7 0.13 10.7 0.1 2.9 2 1 0 2 2 2 2 Benzoate membrane transport protein Sulfate_transp PF00916.15 EDN05210.1 - 0.0015 17.5 9.5 0.0015 17.5 6.6 2.6 1 1 1 2 2 2 1 Sulfate transporter family FUSC-like PF12805.2 EDN05210.1 - 0.99 8.2 2.3 1.8 7.3 1.6 1.4 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS PhyH PF05721.8 EDN05211.1 - 6.1e-43 147.3 0.0 1.3e-42 146.2 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UTP15_C PF09384.5 EDN05212.1 - 8.6e-55 184.5 0.1 6.1e-54 181.7 0.0 2.0 1 1 1 2 2 2 1 UTP15 C terminal WD40 PF00400.27 EDN05212.1 - 2.2e-28 97.0 0.9 6.8e-09 35.2 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EDN05212.1 - 0.002 17.6 0.4 0.86 9.0 0.0 2.4 2 0 0 2 2 2 2 PQQ-like domain L31 PF09784.4 EDN05212.1 - 2.9 8.0 6.3 6.6 6.8 3.2 2.4 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L31 C2 PF00168.25 EDN05213.1 - 9.4e-13 47.8 0.0 2e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain DDE_1 PF03184.14 EDN05215.1 - 1.1e-31 109.6 0.0 1.7e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN05215.1 - 1.7e-13 50.1 1.4 1.9e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN05215.1 - 5.2e-06 25.9 0.1 1.3e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain AAA_27 PF13514.1 EDN05215.1 - 0.052 11.2 0.8 0.076 10.6 0.5 1.1 1 0 0 1 1 1 0 AAA domain HTH_Tnp_1 PF01527.15 EDN05215.1 - 0.1 12.5 0.0 0.31 11.0 0.0 1.9 1 0 0 1 1 1 0 Transposase HNH_2 PF13391.1 EDN05216.1 - 0.00092 18.9 0.1 0.0014 18.3 0.1 1.4 1 0 0 1 1 1 1 HNH endonuclease AAA_12 PF13087.1 EDN05217.1 - 3.7e-23 81.9 0.0 4.9e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Serglycin PF04360.7 EDN05217.1 - 0.089 12.5 1.7 0.13 12.0 0.3 1.9 2 0 0 2 2 2 0 Serglycin UvrD_C PF13361.1 EDN05217.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain RRM_1 PF00076.17 EDN05221.1 - 6.1e-51 169.9 0.0 9.7e-18 63.5 0.0 5.3 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN05221.1 - 2.9e-40 136.0 0.1 2.1e-12 46.8 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN05221.1 - 2.8e-22 78.3 0.0 8.3e-06 25.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDN05221.1 - 6.4e-05 22.6 0.0 0.18 11.5 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 EDN05221.1 - 0.0013 18.0 0.5 0.0035 16.6 0.3 1.7 1 0 0 1 1 1 1 Lsm interaction motif TPR_14 PF13428.1 EDN05221.1 - 0.059 14.0 5.0 0.51 11.1 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat IncFII_repA PF02387.10 EDN05221.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 IncFII RepA protein family NPHI_C PF08469.5 EDN05221.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Nucleoside triphosphatase I C-terminal PepSY_TM_2 PF13703.1 EDN05222.1 - 0.094 12.8 0.2 0.16 12.1 0.1 1.5 1 1 0 1 1 1 0 PepSY-associated TM helix L_HGMIC_fpl PF10242.4 EDN05223.1 - 0.0016 18.5 8.0 0.0038 17.2 5.4 1.8 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF4293 PF14126.1 EDN05223.1 - 0.43 10.4 4.8 4.6 7.1 0.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Amastin PF07344.6 EDN05223.1 - 0.47 10.0 9.7 0.65 9.6 3.6 2.2 2 0 0 2 2 2 0 Amastin surface glycoprotein His_Phos_1 PF00300.17 EDN05224.1 - 2e-14 53.9 0.0 2.9e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HNH_2 PF13391.1 EDN05225.1 - 3.5e-12 45.9 0.0 6.3e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease MARVEL PF01284.18 EDN05229.1 - 1.5e-20 73.4 12.5 1.7e-20 73.2 8.6 1.0 1 0 0 1 1 1 1 Membrane-associating domain Cytochrom_B_N PF00033.14 EDN05229.1 - 0.049 12.9 2.2 0.07 12.4 1.6 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Pkinase PF00069.20 EDN05230.1 - 1.9e-44 151.7 0.0 1e-43 149.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05230.1 - 4.8e-19 68.4 0.0 1e-18 67.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EDN05230.1 - 4.5e-07 29.9 0.0 9.2e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EDN05230.1 - 1.4e-05 24.2 0.0 2.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN05230.1 - 0.042 13.5 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EDN05230.1 - 0.045 12.5 0.3 0.069 11.9 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YukC PF10140.4 EDN05230.1 - 0.098 11.2 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC PRELI PF04707.9 EDN05231.1 - 1e-24 86.9 0.0 2.9e-21 75.6 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family UQ_con PF00179.21 EDN05232.1 - 6.5e-27 93.6 0.0 8.7e-27 93.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDN05232.1 - 0.083 12.7 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain Chitin_synth_1 PF01644.12 EDN05233.1 - 4.9e-69 231.3 0.0 7.2e-69 230.7 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EDN05233.1 - 6.1e-28 96.3 0.0 1.2e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EDN05233.1 - 4.2e-25 88.1 0.0 1.1e-19 70.2 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EDN05233.1 - 4.6e-11 42.8 0.4 4.6e-11 42.8 0.3 3.0 4 1 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDN05233.1 - 1.2e-06 28.5 0.0 5.2e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Aminotran_4 PF01063.14 EDN05234.1 - 1.6e-27 96.4 0.0 4.4e-27 95.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class IV DUF1049 PF06305.6 EDN05235.1 - 0.095 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) TAF8_C PF10406.4 EDN05236.1 - 7.7e-23 80.2 0.9 1.4e-22 79.4 0.2 1.9 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EDN05236.1 - 1.5e-07 31.0 0.0 3.5e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated Mitochondr_Som1 PF11093.3 EDN05237.1 - 1.1e-05 25.1 0.1 1.4e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 PALP PF00291.20 EDN05239.1 - 3.3e-67 226.8 3.3 4.7e-67 226.3 2.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4597 PF15366.1 EDN05239.1 - 0.11 12.1 0.3 0.63 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) IlvC PF01450.14 EDN05240.1 - 9e-45 152.1 0.0 1.3e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 EDN05240.1 - 1.2e-44 151.5 0.0 1.8e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EDN05240.1 - 0.029 14.1 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2OG-FeII_Oxy_2 PF13532.1 EDN05241.1 - 1.6e-22 80.3 0.0 4.6e-22 78.8 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 EDN05241.1 - 4.9e-21 75.4 0.0 1.4e-13 51.1 0.0 2.4 2 0 0 2 2 2 2 Isochorismatase family GST_C PF00043.20 EDN05241.1 - 0.013 15.4 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDN05241.1 - 0.059 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDN05241.1 - 0.067 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ECH PF00378.15 EDN05242.1 - 2.8e-33 115.0 0.1 5.3e-33 114.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2188 PF09954.4 EDN05242.1 - 0.05 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) UPF0506 PF11703.3 EDN05242.1 - 0.053 13.4 0.1 0.094 12.6 0.1 1.3 1 0 0 1 1 1 0 UPF0506 Methyltrn_RNA_4 PF09936.4 EDN05242.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase zf-C2H2_4 PF13894.1 EDN05244.1 - 0.0015 18.7 0.7 0.0015 18.7 0.5 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger RNA_pol_Rpb1_5 PF04998.12 EDN05245.1 - 7e-89 297.7 1.6 1.3e-88 296.8 1.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EDN05245.1 - 3.7e-83 279.5 0.0 5.6e-83 278.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EDN05245.1 - 2.6e-67 225.9 0.1 5.6e-67 224.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EDN05245.1 - 3.1e-36 124.4 0.0 1e-35 122.8 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EDN05245.1 - 1.2e-27 95.8 0.0 3.1e-27 94.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rpr2 PF04032.11 EDN05245.1 - 0.79 9.6 4.5 0.89 9.4 1.6 2.3 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GTP_EFTU PF00009.22 EDN05246.1 - 8.2e-49 165.5 0.0 1.3e-48 164.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EDN05246.1 - 3.8e-36 123.2 5.3 6.4e-36 122.5 3.7 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EDN05246.1 - 2e-18 66.0 0.0 3.5e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 EDN05246.1 - 4.5e-05 23.3 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EDN05246.1 - 0.0001 22.3 0.0 0.00025 21.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 EDN05246.1 - 0.00041 19.7 0.0 0.00089 18.6 0.0 1.6 1 0 0 1 1 1 1 Ras family EFG_II PF14492.1 EDN05246.1 - 0.0086 15.9 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 EDN05246.1 - 0.03 13.5 0.0 0.068 12.3 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit HORMA PF02301.13 EDN05247.1 - 3.6e-50 170.3 0.1 4.2e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 HORMA domain Alba PF01918.16 EDN05247.1 - 0.093 12.3 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Alba Sec1 PF00995.18 EDN05249.1 - 1.2e-138 463.2 0.0 6e-93 312.4 0.0 2.0 1 1 1 2 2 2 2 Sec1 family WHG PF13305.1 EDN05249.1 - 0.15 12.6 0.0 0.71 10.4 0.0 2.2 2 0 0 2 2 2 0 WHG domain DUF755 PF05501.6 EDN05251.1 - 0.12 12.4 4.0 0.18 11.8 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF755) GRP PF07172.6 EDN05252.1 - 0.013 15.9 4.8 0.026 14.9 3.3 1.5 1 0 0 1 1 1 0 Glycine rich protein family PAT1 PF09770.4 EDN05252.1 - 0.25 9.5 48.8 0.0021 16.3 23.5 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Mitoc_L55 PF09776.4 EDN05252.1 - 0.87 9.1 3.8 5.7 6.5 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 FHA PF00498.21 EDN05253.1 - 4.5e-11 42.7 0.0 1.2e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 FHA domain TPR_11 PF13414.1 EDN05254.1 - 1.5e-53 178.3 50.5 4e-12 45.5 1.3 7.6 2 2 9 11 11 11 11 TPR repeat TPR_1 PF00515.23 EDN05254.1 - 6.1e-36 120.5 32.8 2.1e-06 27.0 0.0 11.4 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 EDN05254.1 - 2.3e-34 114.5 32.2 9.2e-05 22.0 0.0 11.6 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.1 EDN05254.1 - 1.4e-22 79.8 30.0 2.8e-08 34.2 0.8 7.1 6 1 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EDN05254.1 - 1.9e-21 75.7 30.0 3e-05 23.8 0.4 7.3 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 EDN05254.1 - 4.6e-18 63.8 15.8 0.0027 17.7 0.0 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 EDN05254.1 - 9.1e-14 50.1 22.9 0.0091 15.7 0.0 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 EDN05254.1 - 1.1e-12 47.5 17.0 7.3e-07 28.9 1.3 6.5 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDN05254.1 - 4.5e-12 44.8 17.3 0.054 13.3 0.2 9.7 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDN05254.1 - 1.8e-11 44.2 21.8 9.1e-06 25.9 0.7 6.8 6 1 1 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EDN05254.1 - 1.2e-10 41.3 21.4 0.019 15.0 0.4 5.4 3 1 3 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EDN05254.1 - 3.1e-10 39.7 26.0 0.023 15.3 0.5 9.6 4 3 6 10 10 10 5 Tetratricopeptide repeat SHNi-TPR PF10516.4 EDN05254.1 - 0.00042 19.4 10.0 4.9 6.4 0.0 6.4 6 0 0 6 6 6 1 SHNi-TPR TPR_6 PF13174.1 EDN05254.1 - 0.00056 20.2 18.5 4.1 8.0 0.2 9.0 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF3856 PF12968.2 EDN05254.1 - 0.0033 17.2 4.4 1.9 8.2 0.0 4.5 4 2 0 4 4 4 2 Domain of Unknown Function (DUF3856) DUF1510 PF07423.6 EDN05254.1 - 0.0081 15.5 1.3 0.015 14.7 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 EDN05254.1 - 0.25 10.8 5.8 0.057 12.9 1.2 1.9 2 0 0 2 2 2 0 SpoIIIAH-like protein TPR_10 PF13374.1 EDN05254.1 - 0.55 10.2 17.9 3.9 7.5 0.5 6.2 8 0 0 8 8 5 0 Tetratricopeptide repeat Sel1 PF08238.7 EDN05254.1 - 0.56 10.9 5.7 31 5.3 0.1 4.2 3 0 0 3 3 3 0 Sel1 repeat TPR_4 PF07721.9 EDN05254.1 - 0.6 10.7 13.4 26 5.6 0.1 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Zip PF02535.17 EDN05255.1 - 4e-37 127.9 9.1 7e-37 127.1 6.3 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.7 EDN05255.1 - 7.4e-05 22.1 6.8 7.4e-05 22.1 4.7 2.4 2 0 0 2 2 2 1 HupE / UreJ protein Thyroglobulin_1 PF00086.13 EDN05255.1 - 0.22 10.9 1.8 46 3.4 0.1 3.3 3 0 0 3 3 3 0 Thyroglobulin type-1 repeat YniB PF14002.1 EDN05255.1 - 6.2 6.2 7.5 4.5 6.6 0.2 2.9 2 1 1 3 3 3 0 YniB-like protein DUF4175 PF13779.1 EDN05256.1 - 0.003 15.3 0.0 0.0038 15.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) TRAP_alpha PF03896.11 EDN05256.1 - 0.04 12.9 1.0 0.058 12.3 0.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Na_trans_assoc PF06512.8 EDN05256.1 - 0.047 13.6 2.8 0.079 12.9 2.0 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Nucleoplasmin PF03066.10 EDN05256.1 - 0.068 12.6 9.0 0.11 12.0 6.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin RNA_pol_Rpc4 PF05132.9 EDN05256.1 - 0.29 11.1 3.0 0.5 10.3 2.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Myb_Cef PF11831.3 EDN05256.1 - 0.43 9.7 6.8 0.67 9.1 4.7 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component YqfQ PF14181.1 EDN05256.1 - 1 9.3 5.1 1.8 8.5 3.6 1.3 1 0 0 1 1 1 0 YqfQ-like protein Daxx PF03344.10 EDN05256.1 - 1.2 7.5 8.9 1.7 7.0 6.2 1.1 1 0 0 1 1 1 0 Daxx Family HSP90 PF00183.13 EDN05256.1 - 1.5 7.1 11.7 2.1 6.6 8.1 1.1 1 0 0 1 1 1 0 Hsp90 protein TFIIF_alpha PF05793.7 EDN05256.1 - 3.5 5.9 13.6 4.8 5.4 9.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 EDN05256.1 - 6.2 4.6 11.3 1 7.1 5.3 1.5 2 0 0 2 2 2 0 Nop14-like family VID27 PF08553.5 EDN05256.1 - 9.2 4.3 9.3 13 3.8 6.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein FAD_binding_3 PF01494.14 EDN05257.1 - 6.2e-11 41.9 0.9 5.5e-08 32.2 0.0 3.0 3 0 0 3 3 3 2 FAD binding domain SE PF08491.5 EDN05257.1 - 0.023 13.5 0.0 0.16 10.7 0.0 2.3 2 1 1 3 3 3 0 Squalene epoxidase NAD_binding_8 PF13450.1 EDN05257.1 - 0.029 14.3 0.5 0.084 12.9 0.3 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain VPEP PF07589.6 EDN05257.1 - 0.36 10.7 1.8 2 8.4 0.0 2.7 2 0 0 2 2 2 0 PEP-CTERM motif Opy2 PF09463.5 EDN05258.1 - 1.4e-11 44.2 21.1 2.2e-11 43.6 14.6 1.3 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 EDN05258.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Glyoxalase_2 PF12681.2 EDN05259.1 - 3.4e-10 40.4 0.0 4.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EDN05259.1 - 3.5e-05 23.7 0.0 8.2e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Tbf5 PF06331.7 EDN05260.1 - 1.8e-26 91.7 0.5 2e-26 91.5 0.3 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF1325 PF07039.6 EDN05260.1 - 0.1 12.2 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 SGF29 tudor-like domain EABR PF12180.3 EDN05260.1 - 0.11 11.8 0.4 0.25 10.7 0.3 1.6 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 PHO4 PF01384.15 EDN05261.1 - 6.9e-112 373.2 9.2 8.1e-112 373.0 6.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family PhyH PF05721.8 EDN05262.1 - 5.5e-15 55.9 0.2 3e-11 43.7 0.1 2.1 1 1 1 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) RVT_1 PF00078.22 EDN05263.1 - 8.3e-35 120.0 0.0 1.6e-34 119.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN05263.1 - 1.4e-16 60.1 0.0 7.3e-16 57.8 0.0 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN05263.1 - 1.3e-07 31.8 0.0 2.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EDN05263.1 - 0.00053 19.7 4.1 0.00053 19.7 2.9 2.6 3 0 0 3 3 3 1 Zinc knuckle DUF837 PF05769.6 EDN05263.1 - 0.16 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF837) zf-CCHC_4 PF14392.1 EDN05263.1 - 0.89 9.2 12.8 3.1 7.5 1.0 2.7 1 1 1 2 2 2 0 Zinc knuckle KH_3 PF13014.1 EDN05264.1 - 0.078 12.6 0.7 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 KH domain DEAD PF00270.24 EDN05266.1 - 1.4e-15 57.2 0.0 4.7e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN05266.1 - 3e-15 55.8 0.1 9.1e-15 54.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN05266.1 - 6.3e-05 22.8 5.7 6.8e-05 22.7 0.0 3.6 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit Rgp1 PF08737.5 EDN05267.1 - 0.02 14.0 0.1 0.031 13.3 0.1 1.3 1 0 0 1 1 1 0 Rgp1 DDE_1 PF03184.14 EDN05269.1 - 8.3e-38 129.6 0.0 1.1e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN05269.1 - 7.2e-07 29.0 0.0 2.5e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease RNase_H PF00075.19 EDN05270.1 - 7.1e-10 39.3 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN05270.1 - 0.042 13.6 0.1 0.17 11.6 0.1 2.0 1 1 0 1 1 1 0 Reverse transcriptase-like RVT_2 PF07727.9 EDN05271.1 - 3.2e-42 144.2 0.0 1.4e-41 142.1 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4219 PF13961.1 EDN05272.1 - 0.0024 17.2 0.2 0.0045 16.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Mito_fiss_reg PF05308.6 EDN05272.1 - 7.1 5.9 16.6 0.4 9.9 4.6 2.0 1 1 1 2 2 2 0 Mitochondrial fission regulator BCS1_N PF08740.6 EDN05274.1 - 2e-41 141.6 0.0 3.2e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN05274.1 - 1e-19 71.0 0.0 4.2e-19 69.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN05274.1 - 0.00034 20.6 0.5 0.00093 19.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EDN05274.1 - 0.0048 17.7 0.0 0.037 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN05274.1 - 0.0097 15.3 0.0 0.022 14.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Queuosine_synth PF02547.10 EDN05274.1 - 0.012 14.3 0.0 0.023 13.4 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein AAA_5 PF07728.9 EDN05274.1 - 0.035 13.8 0.0 0.11 12.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN05274.1 - 0.042 14.0 0.0 0.2 11.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EDN05274.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.1 EDN05274.1 - 0.076 12.8 0.2 0.4 10.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EDN05274.1 - 0.077 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain PPV_E1_C PF00519.12 EDN05274.1 - 0.1 11.2 0.0 0.18 10.3 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase RuvB_N PF05496.7 EDN05274.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Tegument_dsDNA PF12818.2 EDN05275.1 - 0.018 13.9 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 dsDNA viral tegument protein Acetyltransf_7 PF13508.1 EDN05275.1 - 0.066 13.3 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDN05275.1 - 0.11 12.3 0.1 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN05275.1 - 0.13 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Lac_bphage_repr PF06543.7 EDN05277.1 - 0.065 12.7 1.4 0.16 11.5 0.9 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor RNase_H PF00075.19 EDN05278.1 - 4.9e-07 30.1 0.0 8.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 RNase H DUF3435 PF11917.3 EDN05279.1 - 2.3e-163 543.8 0.6 2.9e-163 543.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EDN05279.1 - 1.3e-06 28.1 0.2 0.00023 20.8 0.0 2.5 2 0 0 2 2 2 2 Phage integrase family Peptidase_M24 PF00557.19 EDN05281.1 - 4.2e-46 157.1 0.1 5.6e-46 156.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EDN05281.1 - 1.6e-17 63.1 0.0 4e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Nexin_C PF08628.7 EDN05282.1 - 3.1e-08 33.7 0.0 5.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 EDN05282.1 - 4.9e-08 32.7 0.1 9.7e-07 28.5 0.0 2.3 2 0 0 2 2 2 1 PX domain Acyl_transf_1 PF00698.16 EDN05283.1 - 1.5e-15 57.3 0.0 1.4e-13 50.9 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain GDPD PF03009.12 EDN05284.1 - 0.00031 20.3 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EDN05285.1 - 3.3e-35 120.2 3.4 2.1e-13 50.4 0.1 3.4 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDN05285.1 - 7.5e-31 105.9 7.6 9.6e-13 48.2 0.0 6.1 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 EDN05285.1 - 8.4e-25 85.3 13.5 1e-05 25.0 0.0 8.5 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 EDN05285.1 - 7.9e-19 67.2 10.1 5.7e-06 26.3 0.0 6.6 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN05285.1 - 3.1e-18 64.0 11.3 0.00058 19.8 0.0 8.3 9 0 0 9 9 9 4 Ankyrin repeat SKG6 PF08693.5 EDN05287.1 - 5.3e-08 32.0 3.2 1.1e-07 31.0 2.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EDN05287.1 - 0.00055 19.4 0.0 0.00078 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Rifin_STEVOR PF02009.11 EDN05287.1 - 0.0028 17.3 0.0 0.004 16.8 0.0 1.1 1 0 0 1 1 1 1 Rifin/stevor family VSP PF03302.8 EDN05287.1 - 0.0033 16.1 0.2 0.0046 15.6 0.2 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4381 PF14316.1 EDN05287.1 - 0.045 13.8 0.1 0.087 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3301 PF11743.3 EDN05287.1 - 0.13 11.7 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) CcmD PF04995.9 EDN05287.1 - 0.15 11.8 1.3 0.24 11.1 0.9 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Herpes_gE PF02480.11 EDN05287.1 - 0.18 10.0 0.0 0.18 10.0 0.0 2.1 1 1 2 3 3 3 0 Alphaherpesvirus glycoprotein E EzrA PF06160.7 EDN05287.1 - 0.26 9.4 0.1 0.33 9.0 0.1 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DOR PF14839.1 EDN05288.1 - 0.0021 17.8 7.6 0.0024 17.6 5.3 1.1 1 0 0 1 1 1 1 DOR family BLVR PF06375.6 EDN05288.1 - 0.013 15.3 2.9 0.016 15.0 2.0 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Sec62 PF03839.11 EDN05288.1 - 0.022 14.1 1.9 0.024 14.0 1.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S49_N PF08496.5 EDN05288.1 - 0.046 13.5 2.5 0.055 13.2 1.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal XRCC4 PF06632.7 EDN05288.1 - 0.085 11.7 2.5 0.086 11.6 1.8 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PGA2 PF07543.7 EDN05288.1 - 0.16 11.7 6.4 0.24 11.1 4.5 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 Sugar_tr PF00083.19 EDN05289.1 - 4.1e-92 309.1 3.2 3.8e-73 246.6 0.0 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDN05289.1 - 6.2e-21 74.4 18.0 7.8e-13 47.8 3.8 3.3 1 1 1 3 3 3 2 Major Facilitator Superfamily LacY_symp PF01306.14 EDN05289.1 - 8.1e-05 21.3 3.4 0.0024 16.4 0.1 2.3 2 0 0 2 2 2 2 LacY proton/sugar symporter PspC PF04024.7 EDN05289.1 - 0.035 13.5 0.3 0.21 11.0 0.2 2.3 1 0 0 1 1 1 0 PspC domain DUF829 PF05705.9 EDN05289.1 - 0.075 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) ABC_tran PF00005.22 EDN05290.1 - 7.6e-49 165.5 0.2 2.9e-23 82.6 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EDN05290.1 - 3.1e-20 71.7 5.9 3.1e-20 71.7 4.1 3.7 4 0 0 4 4 4 1 ABC transporter AAA_21 PF13304.1 EDN05290.1 - 4.2e-17 63.0 0.6 0.0011 19.0 0.0 4.5 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EDN05290.1 - 2e-11 43.5 0.5 0.0067 15.6 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EDN05290.1 - 6.5e-09 36.6 0.2 0.0085 16.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 EDN05290.1 - 1.1e-07 31.2 2.7 0.32 9.9 0.0 4.7 4 2 1 5 5 5 3 AAA ATPase domain Miro PF08477.8 EDN05290.1 - 2.6e-06 27.9 0.0 0.02 15.4 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 EDN05290.1 - 2.8e-06 27.6 0.2 0.25 11.6 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EDN05290.1 - 5e-06 25.9 0.4 0.077 12.5 0.1 3.0 2 1 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EDN05290.1 - 5.6e-06 25.6 0.0 0.048 12.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDN05290.1 - 1.6e-05 24.9 0.1 0.024 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EDN05290.1 - 1.8e-05 24.9 0.0 0.2 11.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EDN05290.1 - 2.1e-05 24.4 0.0 0.093 12.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 EDN05290.1 - 4.8e-05 23.0 0.1 0.19 11.4 0.1 3.1 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EDN05290.1 - 0.00013 21.9 2.1 0.062 13.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 EDN05290.1 - 0.00018 21.3 4.4 0.39 10.5 0.0 3.9 4 0 0 4 4 3 2 Dynamin family AAA_33 PF13671.1 EDN05290.1 - 0.00019 21.3 0.0 0.53 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EDN05290.1 - 0.00025 21.4 14.5 0.036 14.4 0.0 4.7 5 0 0 5 5 5 2 AAA domain NACHT PF05729.7 EDN05290.1 - 0.00039 20.1 0.1 0.6 9.7 0.0 2.5 2 0 0 2 2 2 2 NACHT domain ArgK PF03308.11 EDN05290.1 - 0.00073 18.3 0.1 0.77 8.4 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA PF00004.24 EDN05290.1 - 0.00087 19.5 0.0 0.78 9.9 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EDN05290.1 - 0.0016 17.9 0.2 1.6 8.1 0.0 3.6 4 1 0 4 4 3 1 AAA-like domain AAA_14 PF13173.1 EDN05290.1 - 0.002 18.0 0.0 2.2 8.1 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.1 EDN05290.1 - 0.0025 17.4 0.6 0.16 11.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EDN05290.1 - 0.0046 17.1 0.0 2.5 8.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 EDN05290.1 - 0.0052 15.8 0.0 0.59 9.1 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin NTPase_1 PF03266.10 EDN05290.1 - 0.0075 15.9 0.1 1.3 8.7 0.0 2.7 2 0 0 2 2 2 1 NTPase AAA_25 PF13481.1 EDN05290.1 - 0.0086 15.4 0.0 5.7 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EDN05290.1 - 0.01 15.7 0.3 4.1 7.3 0.1 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 EDN05290.1 - 0.014 14.9 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 EDN05290.1 - 0.018 14.5 0.4 1.5 8.2 0.3 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EDN05290.1 - 0.025 13.4 0.0 5.3 5.8 0.0 2.9 3 0 0 3 3 2 0 NB-ARC domain AAA_24 PF13479.1 EDN05290.1 - 0.028 14.0 0.1 5.2 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EDN05290.1 - 0.032 13.1 0.1 0.41 9.5 0.0 2.4 2 1 0 2 2 2 0 Type II/IV secretion system protein SRP54 PF00448.17 EDN05290.1 - 0.056 12.8 1.5 3.5 7.0 0.0 3.4 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 EDN05290.1 - 0.071 12.8 0.3 7.4 6.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EDN05290.1 - 0.11 11.9 0.0 18 4.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 EDN05290.1 - 0.33 10.7 8.3 1.9 8.2 0.0 4.0 5 0 0 5 5 4 0 Domain of unknown function DUF87 LGFP PF08310.6 EDN05291.1 - 0.13 11.9 0.0 0.93 9.1 0.0 2.3 2 1 1 3 3 3 0 LGFP repeat RMF PF04957.7 EDN05294.1 - 4.6 6.9 7.0 0.62 9.8 0.8 2.3 2 1 1 3 3 3 0 Ribosome modulation factor WD40 PF00400.27 EDN05295.1 - 4.5e-30 102.4 8.9 3.1e-13 49.0 0.4 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EDN05295.1 - 0.002 17.8 3.9 0.0091 15.7 1.6 2.5 2 1 0 3 3 3 1 Transcription factor IIIC subunit delta N-term ATP_synth_reg PF14960.1 EDN05295.1 - 0.0029 16.7 0.1 0.0055 15.8 0.1 1.4 1 0 0 1 1 1 1 ATP synthase regulation SNF5 PF04855.7 EDN05298.1 - 4.1e-61 206.5 0.0 5e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EDN05298.1 - 8.3e-05 21.8 2.4 8.3e-05 21.8 1.7 1.9 2 0 0 2 2 2 1 GATA zinc finger PIG-X PF08320.7 EDN05298.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 PIG-X / PBN1 Peptidase_M49 PF03571.10 EDN05299.1 - 3.1e-226 751.7 0.0 4.1e-226 751.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Pkinase PF00069.20 EDN05300.1 - 3.3e-14 52.6 0.0 7.3e-14 51.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05300.1 - 3.2e-08 32.9 0.0 1.5e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Aminotran_4 PF01063.14 EDN05302.1 - 2.5e-29 102.3 0.0 3.4e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV CK_II_beta PF01214.13 EDN05303.1 - 1.7e-21 76.6 0.0 2.3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF2457 PF10446.4 EDN05303.1 - 0.075 11.7 8.6 1.5 7.4 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Peptidase_M90 PF06167.7 EDN05303.1 - 0.098 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 Spt5_N PF11942.3 EDN05303.1 - 5.8 7.6 16.4 0.71 10.5 6.4 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.6 EDN05303.1 - 6.3 4.7 5.8 0.43 8.6 0.7 1.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Zn_clus PF00172.13 EDN05304.1 - 0.0006 19.6 10.7 0.0011 18.8 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_8 PF13621.1 EDN05305.1 - 4.4e-10 39.4 0.0 5e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EDN05305.1 - 0.037 13.2 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein JmjC PF02373.17 EDN05305.1 - 0.047 13.9 0.0 0.07 13.3 0.0 1.2 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_2 PF07883.6 EDN05305.1 - 0.073 12.5 0.1 0.099 12.1 0.1 1.3 1 0 0 1 1 1 0 Cupin domain AA_permease PF00324.16 EDN05306.1 - 6.4e-93 311.6 25.6 7.8e-93 311.3 17.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDN05306.1 - 4.4e-20 71.6 25.9 6e-20 71.1 18.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EDN05306.1 - 0.0096 15.6 3.6 0.0096 15.6 2.5 3.4 2 1 1 3 3 3 1 Domain of unknown function (DUF1772) Cyt-b5 PF00173.23 EDN05307.1 - 3.9e-10 39.3 0.0 4.6e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.17 EDN05308.1 - 3.7e-61 202.6 0.0 6.5e-20 70.5 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN05308.1 - 1.2e-41 140.5 0.0 1.9e-13 50.1 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN05308.1 - 1.3e-21 76.1 0.0 7.5e-09 35.3 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HVSL PF09749.4 EDN05308.1 - 0.015 14.3 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein Fungal_trans_2 PF11951.3 EDN05309.1 - 3.3e-05 22.6 0.4 0.0053 15.3 0.0 2.3 2 1 0 2 2 2 2 Fungal specific transcription factor domain Nitr_red_bet_C PF14711.1 EDN05309.1 - 0.22 11.0 3.4 14 5.2 0.0 2.6 2 0 0 2 2 2 0 Respiratory nitrate reductase beta C-terminal ABC_tran PF00005.22 EDN05310.1 - 2.1e-45 154.4 0.0 1.4e-31 109.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDN05310.1 - 3.7e-42 144.6 15.0 5.9e-42 143.9 10.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EDN05310.1 - 1.1e-13 51.8 0.0 0.00026 21.0 0.0 3.3 3 0 0 3 3 3 3 AAA domain SMC_N PF02463.14 EDN05310.1 - 7.4e-12 44.9 4.0 1.2e-05 24.6 0.0 3.2 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EDN05310.1 - 9.4e-11 40.9 0.9 0.00012 20.8 0.1 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class SbcCD_C PF13558.1 EDN05310.1 - 3.1e-05 23.7 3.3 0.2 11.6 0.2 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 EDN05310.1 - 0.00039 20.4 0.2 0.0017 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 EDN05310.1 - 0.0025 17.8 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDN05310.1 - 0.0025 17.9 0.6 0.4 10.8 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN05310.1 - 0.0047 17.7 0.0 0.016 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EDN05310.1 - 0.0094 15.5 0.5 0.88 9.1 0.1 3.1 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EDN05310.1 - 0.0097 15.1 0.0 0.022 13.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EDN05310.1 - 0.011 14.8 0.0 0.16 11.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 EDN05310.1 - 0.013 15.6 0.6 5.2 7.2 0.1 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EDN05310.1 - 0.017 14.5 0.6 0.083 12.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EDN05310.1 - 0.029 13.9 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RelB_N PF12910.2 EDN05310.1 - 0.15 11.4 0.5 0.4 10.0 0.3 1.7 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin stability system N-terminal AAA_15 PF13175.1 EDN05310.1 - 0.21 10.5 0.0 0.4 9.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Fungal_trans PF04082.13 EDN05311.1 - 1.1e-15 57.2 1.6 2e-15 56.3 0.8 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain c-SKI_SMAD_bind PF08782.5 EDN05311.1 - 0.0094 16.0 3.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 2 c-SKI Smad4 binding domain TRAM_LAG1_CLN8 PF03798.11 EDN05312.1 - 9.2e-29 100.4 15.9 1.6e-28 99.6 11.0 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EDN05312.1 - 1.2e-19 69.5 1.5 1.8e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 TRAM1-like protein DUF2973 PF11189.3 EDN05312.1 - 0.0095 15.6 0.2 0.39 10.5 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2973) DUF788 PF05620.6 EDN05312.1 - 0.45 10.3 2.3 1.4 8.7 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF788) ATP-synt_8 PF00895.15 EDN05313.1 - 2 8.6 6.6 8.7 6.6 0.3 2.9 2 0 0 2 2 2 0 ATP synthase protein 8 4F5 PF04419.9 EDN05314.1 - 2.1e-10 41.1 12.1 2.1e-10 41.1 8.4 2.5 2 1 0 2 2 2 1 4F5 protein family Phage_Gp23 PF10669.4 EDN05314.1 - 0.89 9.6 5.3 0.98 9.5 3.7 1.0 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) PP28 PF10252.4 EDN05314.1 - 4.6 7.3 17.1 5.9 6.9 11.8 1.2 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 CHD5 PF04420.9 EDN05316.1 - 8.8e-60 201.0 1.1 1e-59 200.7 0.8 1.0 1 0 0 1 1 1 1 CHD5-like protein Lebercilin PF15619.1 EDN05316.1 - 0.013 14.9 1.0 0.018 14.5 0.7 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease tRNA_lig_CPD PF08302.6 EDN05316.1 - 0.047 12.9 1.0 0.065 12.4 0.7 1.1 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain WXG100 PF06013.7 EDN05316.1 - 0.25 11.3 2.1 0.41 10.6 1.5 1.3 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF4407 PF14362.1 EDN05318.1 - 3.9 6.3 9.9 4.7 6.0 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRM_1 PF00076.17 EDN05319.1 - 2e-06 27.3 0.0 4.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN05319.1 - 0.00085 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SPT6_acidic PF14632.1 EDN05319.1 - 6.9 6.9 11.6 4.5 7.4 5.3 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 CENP-N PF05238.8 EDN05324.1 - 2.6e-57 194.7 0.0 2.9e-57 194.5 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like zf-RING_2 PF13639.1 EDN05325.1 - 8.8e-08 31.8 4.8 2e-07 30.7 3.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 EDN05325.1 - 2.3e-05 24.1 1.7 2.3e-05 24.1 1.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger SWIM PF04434.12 EDN05325.1 - 3.8e-05 23.0 0.2 7.1e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_5 PF14634.1 EDN05325.1 - 0.011 15.4 5.2 0.011 15.4 3.6 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.2 EDN05325.1 - 0.026 14.6 6.2 0.026 14.6 4.3 1.9 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EDN05325.1 - 0.032 13.8 5.4 0.064 12.8 3.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EDN05325.1 - 0.032 13.9 5.4 0.1 12.3 3.9 1.8 1 1 1 2 2 2 0 PHD-finger zf-C3HC4_3 PF13920.1 EDN05325.1 - 0.061 13.0 3.4 0.15 11.7 2.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EDN05325.1 - 0.066 13.1 9.8 0.063 13.2 4.1 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 EDN05325.1 - 0.25 11.3 6.5 0.61 10.1 4.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) bZIP_2 PF07716.10 EDN05328.1 - 1.6e-13 50.2 12.7 2.4e-13 49.6 8.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EDN05328.1 - 7.2e-07 29.0 10.9 1e-06 28.5 7.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor Herpes_BLRF2 PF05812.7 EDN05328.1 - 0.00072 19.3 0.2 0.00072 19.3 0.1 1.9 1 1 1 2 2 2 1 Herpesvirus BLRF2 protein CCDC144C PF14915.1 EDN05328.1 - 0.0039 16.1 1.9 0.0047 15.8 1.3 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region Phage-tail_3 PF13550.1 EDN05328.1 - 0.015 15.0 1.4 0.02 14.6 1.0 1.3 1 1 0 1 1 1 0 Putative phage tail protein Phlebovirus_NSM PF07246.6 EDN05328.1 - 0.018 14.1 4.7 0.022 13.9 3.2 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4094 PF13334.1 EDN05328.1 - 0.042 14.2 2.1 0.06 13.7 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF3552 PF12072.3 EDN05328.1 - 0.05 12.8 6.8 0.063 12.4 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TSC22 PF01166.13 EDN05328.1 - 0.074 13.0 0.4 0.15 12.0 0.2 1.5 1 1 0 1 1 1 0 TSC-22/dip/bun family Milton PF12448.3 EDN05328.1 - 0.11 12.6 1.0 0.13 12.4 0.7 1.1 1 0 0 1 1 1 0 Kinesin associated protein BSMAP PF12280.3 EDN05328.1 - 0.13 12.0 0.9 0.16 11.8 0.7 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein V_ATPase_I PF01496.14 EDN05328.1 - 0.21 9.3 0.8 0.23 9.3 0.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PEARLI-4 PF05278.7 EDN05328.1 - 0.64 9.3 4.3 0.8 9.0 3.0 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) BRO1 PF03097.13 EDN05329.1 - 3.1e-114 381.6 0.1 5.8e-114 380.7 0.0 1.5 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EDN05329.1 - 2.6e-46 157.9 5.4 6.9e-46 156.5 2.8 2.4 2 1 1 3 3 3 1 ALIX V-shaped domain binding to HIV Mito_carr PF00153.22 EDN05330.1 - 8.1e-38 128.0 18.6 9.5e-15 54.0 0.1 4.0 4 1 0 4 4 4 3 Mitochondrial carrier protein BAF1_ABF1 PF04684.8 EDN05330.1 - 0.13 11.0 7.1 0.19 10.5 4.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Dishevelled PF02377.10 EDN05330.1 - 0.13 12.4 11.7 0.29 11.3 8.1 1.5 1 0 0 1 1 1 0 Dishevelled specific domain Activator_LAG-3 PF11498.3 EDN05330.1 - 0.99 8.0 18.1 0.064 12.0 7.9 2.3 3 0 0 3 3 3 0 Transcriptional activator LAG-3 APC_CDC26 PF10471.4 EDN05330.1 - 7.7 7.3 14.5 18 6.1 10.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Thiolase_C PF02803.13 EDN05331.1 - 1.7e-11 43.6 2.2 4.8e-11 42.1 0.3 2.5 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EDN05331.1 - 2.2e-07 30.4 0.1 1.4e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EDN05331.1 - 5.4e-05 22.3 0.0 0.00021 20.3 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EDN05331.1 - 0.0095 15.4 0.4 0.021 14.3 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EDN05331.1 - 0.096 12.5 1.4 2.1 8.1 0.0 2.7 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain DUF974 PF06159.8 EDN05332.1 - 9.4e-34 116.9 0.0 1.6e-33 116.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF974) DDE_3 PF13358.1 EDN05333.1 - 9e-09 35.2 1.1 1e-08 35.0 0.8 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DENN PF02141.16 EDN05334.1 - 2e-43 148.2 0.0 2.6e-31 108.7 0.2 2.5 1 1 1 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.13 EDN05334.1 - 2.3e-19 69.1 0.0 5.1e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 uDENN domain HATPase_c_3 PF13589.1 EDN05338.1 - 1.4e-22 79.8 0.0 2.5e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EDN05338.1 - 3.1e-09 36.5 0.0 7.3e-08 32.1 0.0 2.5 2 1 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EDN05338.1 - 0.0021 17.7 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RasGEF PF00617.14 EDN05339.1 - 5.3e-56 189.3 0.0 8.8e-56 188.6 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EDN05339.1 - 1.7e-18 66.6 0.0 5.7e-18 64.9 0.0 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif MARVEL PF01284.18 EDN05340.1 - 0.095 12.5 1.4 0.094 12.5 1.0 1.0 1 0 0 1 1 1 0 Membrane-associating domain Apis_Csd PF11671.3 EDN05340.1 - 3.3 7.4 14.8 3.3 7.4 10.3 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein MIG-14_Wnt-bd PF06664.7 EDN05342.1 - 0.0088 14.9 0.2 0.01 14.6 0.1 1.0 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF4064 PF13273.1 EDN05342.1 - 0.015 15.3 1.4 0.026 14.6 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF1282 PF06930.7 EDN05342.1 - 0.021 14.4 0.4 0.025 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF4013 PF13197.1 EDN05342.1 - 0.025 13.9 2.2 0.028 13.7 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) MARVEL PF01284.18 EDN05342.1 - 0.035 13.9 3.2 0.042 13.6 2.2 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF3810 PF12725.2 EDN05342.1 - 0.072 11.9 0.6 0.084 11.7 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Yip1 PF04893.12 EDN05342.1 - 0.14 11.6 2.7 0.16 11.4 1.9 1.1 1 0 0 1 1 1 0 Yip1 domain CLPTM1 PF05602.7 EDN05343.1 - 0.16 10.6 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Helicase_C PF00271.26 EDN05346.1 - 3e-14 52.6 0.1 6.8e-14 51.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Aft1_HRR PF11787.3 EDN05346.1 - 0.17 12.9 0.5 0.41 11.7 0.4 1.7 1 0 0 1 1 1 0 Aft1 HRR domain Myb_DNA-binding PF00249.26 EDN05347.1 - 0.00013 21.9 0.1 0.00025 21.0 0.1 1.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain DUF573 PF04504.9 EDN05347.1 - 0.00028 21.0 0.9 0.00086 19.5 0.7 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF573 Myb_DNA-bind_6 PF13921.1 EDN05347.1 - 0.0011 19.0 0.2 0.0019 18.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDN05347.1 - 0.0064 16.6 2.4 0.11 12.6 1.6 2.2 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain EndoU_bacteria PF14436.1 EDN05348.1 - 0.1 12.4 0.5 0.53 10.1 0.0 2.4 1 1 1 3 3 3 0 Bacterial EndoU nuclease DNA_pol_E_B PF04042.11 EDN05348.1 - 1.8 7.7 5.8 16 4.7 0.0 3.3 4 0 0 4 4 4 0 DNA polymerase alpha/epsilon subunit B DUF2200 PF09966.4 EDN05350.1 - 0.0083 15.9 0.2 0.049 13.4 0.1 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2200) KH_3 PF13014.1 EDN05350.1 - 0.16 11.6 1.6 4.4 7.0 0.0 2.7 2 0 0 2 2 2 0 KH domain DUF3505 PF12013.3 EDN05355.1 - 5.7e-08 32.9 0.3 6.3e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) SCAN PF02023.12 EDN05359.1 - 0.052 13.0 0.3 0.13 11.7 0.1 1.6 2 0 0 2 2 2 0 SCAN domain Exo_endo_phos_2 PF14529.1 EDN05360.1 - 1.1e-13 50.7 0.0 2.5e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EDN05360.1 - 0.0032 16.8 0.0 0.0055 16.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN05360.1 - 0.0075 16.6 1.2 0.015 15.6 0.0 2.1 2 0 0 2 2 2 1 RNase H DUF3435 PF11917.3 EDN05363.1 - 1.2e-153 511.7 0.1 1.9e-153 511.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EDN05363.1 - 1e-05 25.2 0.1 0.00041 20.0 0.0 2.4 2 0 0 2 2 2 1 Phage integrase family Aldedh PF00171.17 EDN05364.1 - 4.8e-100 335.0 0.0 5.7e-100 334.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Sigma70_r4 PF04545.11 EDN05364.1 - 0.098 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Pro_dh PF01619.13 EDN05365.1 - 4.9e-27 94.7 1.4 8.4e-27 93.9 1.0 1.4 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.19 EDN05365.1 - 0.0047 16.2 0.2 0.016 14.5 0.1 1.9 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF2288 PF10052.4 EDN05365.1 - 0.063 13.0 0.0 0.26 11.0 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) Radical_SAM PF04055.16 EDN05367.1 - 1.9e-24 86.7 0.1 3.9e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EDN05367.1 - 1.5e-23 82.6 0.0 2.2e-22 78.8 0.0 2.6 2 0 0 2 2 2 1 Wyosine base formation Flavodoxin_1 PF00258.20 EDN05367.1 - 1e-08 35.2 0.9 3.8e-07 30.2 0.1 2.7 2 1 0 2 2 2 1 Flavodoxin DDE_1 PF03184.14 EDN05368.1 - 7.9e-52 175.5 0.0 1.5e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN05368.1 - 3.3e-06 26.9 0.0 8.3e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN05368.1 - 4.2e-06 26.4 0.0 1.7e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Smg4_UPF3 PF03467.10 EDN05369.1 - 1.4e-21 77.2 0.0 8.1e-21 74.8 0.0 2.1 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.17 EDN05369.1 - 7.3e-07 28.7 0.0 3.9e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN05369.1 - 8.1e-06 25.7 0.0 0.00031 20.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN05369.1 - 0.0011 18.8 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDN05369.1 - 0.18 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 EDN05369.1 - 0.34 9.3 25.0 0.49 8.8 17.3 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RVT_2 PF07727.9 EDN05370.1 - 1.3e-50 171.7 0.0 2.1e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN05370.1 - 0.00039 20.5 0.0 0.0009 19.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EDN05371.1 - 1.9e-35 122.1 0.0 4.3e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN05371.1 - 8.1e-14 52.1 0.0 2.1e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN05371.1 - 6.5e-11 41.8 0.0 2.4e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase ABM PF03992.11 EDN05372.1 - 3.9e-05 23.6 1.0 0.00016 21.6 0.1 2.1 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase DUF4473 PF14747.1 EDN05372.1 - 0.093 12.9 1.7 0.28 11.4 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) RVT_1 PF00078.22 EDN05374.1 - 2.5e-35 121.7 0.0 4.3e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN05374.1 - 7.8e-14 52.1 0.0 2.1e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN05374.1 - 3e-13 49.4 0.0 6.4e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DDE_1 PF03184.14 EDN05375.1 - 3.4e-09 36.1 0.0 1.4e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease MRP-S26 PF14943.1 EDN05375.1 - 0.012 15.1 10.9 0.031 13.8 7.5 1.6 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 HTH_Tnp_Tc5 PF03221.11 EDN05375.1 - 0.06 13.1 0.1 0.33 10.8 0.0 2.4 2 1 0 2 2 2 0 Tc5 transposase DNA-binding domain CAF-1_p150 PF11600.3 EDN05375.1 - 0.28 10.5 16.4 0.38 10.1 11.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4355 PF14265.1 EDN05375.1 - 0.47 10.3 15.3 15 5.5 10.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) CAP_N PF01213.14 EDN05376.1 - 0.008 15.5 1.1 0.011 15.0 0.7 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EDN05376.1 - 0.017 14.4 3.7 0.032 13.6 2.4 1.4 1 1 1 2 2 2 0 Mitochondrial fission regulator MIP-T3 PF10243.4 EDN05376.1 - 0.32 9.4 3.1 0.34 9.3 2.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RVT_1 PF00078.22 EDN05377.1 - 6.3e-35 120.4 0.0 9.5e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN05377.1 - 3.1e-15 55.8 0.0 9.1e-15 54.3 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN05377.1 - 0.00068 19.6 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Porph_ging PF09697.5 EDN05378.1 - 0.092 12.8 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (Porph_ging) VHS PF00790.14 EDN05379.1 - 3.6e-31 107.6 0.5 7e-31 106.7 0.4 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EDN05379.1 - 1.1e-17 63.1 0.1 1e-16 60.0 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EDN05379.1 - 2.7e-16 58.8 0.2 5.8e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDN05379.1 - 1.2e-13 50.3 0.0 2.7e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 EDN05379.1 - 0.003 16.9 0.6 0.0073 15.7 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif Pkinase PF00069.20 EDN05380.1 - 2.7e-70 236.5 0.0 3.8e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05380.1 - 3e-45 154.3 0.0 4.5e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EDN05380.1 - 2.8e-20 72.4 0.1 1.6e-19 70.0 0.1 2.5 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EDN05380.1 - 7.2e-07 28.4 0.0 1.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.7 EDN05380.1 - 0.042 13.0 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain APH PF01636.18 EDN05380.1 - 0.17 11.5 0.0 0.17 11.5 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family KH_1 PF00013.24 EDN05381.1 - 3e-82 270.1 25.6 1.1e-11 44.2 0.1 13.2 14 1 0 14 14 14 9 KH domain KH_3 PF13014.1 EDN05381.1 - 6.1e-64 210.8 22.6 6.6e-11 41.5 0.9 12.3 12 0 0 12 12 12 9 KH domain SLS PF14611.1 EDN05381.1 - 8.4e-13 48.2 0.3 0.047 13.0 0.0 7.4 4 2 3 7 7 7 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 EDN05381.1 - 5.7e-10 38.6 22.6 0.013 15.0 0.8 7.6 7 1 1 8 8 8 3 KH domain DUF1664 PF07889.7 EDN05381.1 - 0.0044 16.8 0.1 0.014 15.2 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) KH_4 PF13083.1 EDN05381.1 - 0.056 13.0 0.5 9.7 5.9 0.0 4.5 5 0 0 5 5 5 0 KH domain Nucleo_P87 PF07267.6 EDN05382.1 - 0.061 12.0 9.5 0.19 10.3 3.5 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 UCH_1 PF13423.1 EDN05383.1 - 1.7e-75 254.1 0.9 2.5e-75 253.6 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EDN05383.1 - 3.1e-19 69.8 0.0 2e-17 63.9 0.0 2.5 1 1 1 2 2 2 1 Exonuclease UCH PF00443.24 EDN05383.1 - 3.1e-07 29.7 0.4 6.7e-06 25.4 0.3 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase 2-Hacid_dh_C PF02826.14 EDN05384.1 - 9e-55 184.5 0.0 2e-54 183.4 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDN05384.1 - 3.2e-36 123.7 0.0 1.8e-35 121.2 0.0 2.2 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 EDN05384.1 - 0.0079 16.0 0.2 0.026 14.3 0.0 1.9 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 EDN05384.1 - 0.0095 16.2 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 XdhC Rossmann domain Fe-ADH PF00465.14 EDN05385.1 - 8.5e-100 333.9 0.0 1.1e-99 333.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EDN05385.1 - 2.8e-14 53.0 0.2 2.2e-10 40.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EDN05385.1 - 0.034 13.5 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Glyoxalase PF00903.20 EDN05386.1 - 4.1e-33 114.1 0.0 1.7e-17 63.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EDN05386.1 - 6.4e-29 100.7 0.0 5.1e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EDN05386.1 - 1.4e-12 47.6 0.0 8e-05 22.6 0.0 3.5 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EDN05386.1 - 0.00035 20.5 0.0 0.064 13.1 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain MoaF PF10703.4 EDN05386.1 - 0.063 12.3 0.0 0.95 8.4 0.0 2.0 2 0 0 2 2 2 0 Molybdenum cofactor biosynthesis protein F IZUMO PF15005.1 EDN05388.1 - 0.063 13.3 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Izumo sperm-egg fusion DUF4115 PF13464.1 EDN05388.1 - 0.094 12.3 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) Arrestin_N PF00339.24 EDN05389.1 - 2e-15 56.9 0.0 3.4e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EDN05389.1 - 0.00042 20.4 0.0 0.0026 17.8 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EDN05389.1 - 0.0012 18.4 0.0 0.005 16.3 0.0 2.0 3 0 0 3 3 3 1 Arrestin_N terminal like APH PF01636.18 EDN05390.1 - 2.7e-12 46.9 0.0 4.7e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EDN05390.1 - 0.0025 17.0 0.0 0.0077 15.4 0.0 1.7 2 0 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.15 EDN05390.1 - 0.065 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2816 PF10992.3 EDN05390.1 - 0.1 12.1 0.2 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2816) WD40 PF00400.27 EDN05391.1 - 5.5e-20 70.4 14.8 1.1e-06 28.3 0.2 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EDN05391.1 - 0.0013 17.0 0.0 0.0021 16.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain IKI3 PF04762.7 EDN05391.1 - 0.0015 16.4 0.0 0.0027 15.5 0.0 1.3 1 1 0 1 1 1 1 IKI3 family eIF2A PF08662.6 EDN05391.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Miro PF08477.8 EDN05392.1 - 1.4e-36 125.5 0.0 3.2e-19 69.5 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EDN05392.1 - 4.8e-34 115.9 0.0 9.3e-34 115.0 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EDN05392.1 - 6e-29 99.1 0.1 1.2e-28 98.1 0.1 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EDN05392.1 - 2.1e-24 85.7 0.0 5.4e-13 48.6 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EDN05392.1 - 2.2e-10 40.4 0.0 0.00063 19.6 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 EDN05392.1 - 5.8e-06 26.3 1.0 0.0022 18.1 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EDN05392.1 - 1.2e-05 24.2 0.9 0.028 13.7 0.1 2.7 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.1 EDN05392.1 - 1.9e-05 24.7 2.0 0.062 13.2 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.18 EDN05392.1 - 6.2e-05 22.8 1.4 0.4 10.4 0.1 3.6 4 0 0 4 4 4 2 Dynamin family AAA_29 PF13555.1 EDN05392.1 - 8.6e-05 21.9 0.1 0.061 12.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_6 PF13405.1 EDN05392.1 - 9.9e-05 21.9 2.7 0.011 15.5 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain AAA_22 PF13401.1 EDN05392.1 - 0.00014 22.0 0.4 0.67 10.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain EF-hand_8 PF13833.1 EDN05392.1 - 0.00076 19.0 0.8 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair AAA_28 PF13521.1 EDN05392.1 - 0.00091 19.2 0.0 0.44 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EDN05392.1 - 0.00099 18.8 0.0 0.07 12.8 0.1 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EDN05392.1 - 0.014 15.2 0.0 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EDN05392.1 - 0.015 14.7 0.0 25 4.2 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain EF-hand_5 PF13202.1 EDN05392.1 - 0.02 14.1 2.9 0.64 9.4 0.1 2.7 2 0 0 2 2 2 0 EF hand AAA_24 PF13479.1 EDN05392.1 - 0.021 14.4 0.1 0.19 11.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.1 EDN05392.1 - 0.026 14.1 0.5 0.23 11.1 0.1 2.3 2 0 0 2 2 2 0 EF hand RNA_helicase PF00910.17 EDN05392.1 - 0.027 14.6 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.1 EDN05392.1 - 0.028 13.8 0.1 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EDN05392.1 - 0.031 14.5 0.0 8.4 6.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EDN05392.1 - 0.06 12.8 0.1 15 4.9 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EDN05392.1 - 0.14 12.9 0.5 26 5.6 0.3 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EDN05392.1 - 0.19 12.0 0.0 10 6.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Arch_ATPase PF01637.13 EDN05392.1 - 0.23 11.1 0.0 25 4.4 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase DUF500 PF04366.7 EDN05393.1 - 2e-44 150.0 0.2 3.4e-44 149.3 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EDN05393.1 - 1.1e-13 50.2 0.4 2.3e-13 49.3 0.1 1.7 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EDN05393.1 - 2.7e-11 42.7 0.0 7.5e-11 41.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EDN05393.1 - 5.4e-11 41.9 0.0 1.2e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Zds_C PF08632.5 EDN05394.1 - 4.9e-27 93.0 0.2 1.1e-26 91.9 0.1 1.7 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF3435 PF11917.3 EDN05396.1 - 3.9e-162 539.7 0.1 5.4e-162 539.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) SGT1 PF07093.6 EDN05398.1 - 6 5.1 12.4 9.6 4.4 8.6 1.2 1 0 0 1 1 1 0 SGT1 protein WD40 PF00400.27 EDN05401.1 - 0.0025 17.6 2.6 0.21 11.5 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EDN05401.1 - 0.047 12.4 0.0 0.072 11.8 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like GSH_synth_ATP PF03917.12 EDN05402.1 - 7e-99 330.8 0.0 8.7e-99 330.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EDN05402.1 - 7.1e-27 93.5 0.0 1.6e-26 92.4 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic glutathione synthase SNF2_N PF00176.18 EDN05403.1 - 3.7e-22 78.4 1.0 2.5e-15 56.0 0.1 3.0 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN05403.1 - 1.7e-13 50.2 0.0 5.3e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SAM_2 PF07647.12 EDN05403.1 - 0.004 16.9 0.1 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 EDN05403.1 - 0.018 15.0 0.0 0.063 13.3 0.0 1.9 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SNF2_N PF00176.18 EDN05404.1 - 1.4e-63 214.4 0.0 2e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EDN05404.1 - 1.3e-13 50.7 0.0 2.5e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.1 EDN05404.1 - 1.9e-11 43.5 7.2 4.8e-11 42.3 5.0 1.7 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 EDN05404.1 - 8.1e-11 41.6 0.0 2.3e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EDN05404.1 - 1e-08 35.0 7.1 1e-08 35.0 4.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN05404.1 - 5.1e-08 32.4 8.3 5.1e-08 32.4 5.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN05404.1 - 1.5e-07 30.9 7.8 1.5e-07 30.9 5.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDN05404.1 - 2.9e-06 27.2 2.0 9.6e-06 25.6 1.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EDN05404.1 - 1.4e-05 24.8 7.7 1.4e-05 24.8 5.3 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EDN05404.1 - 4.7e-05 23.0 5.8 4.7e-05 23.0 4.0 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 EDN05404.1 - 0.00067 19.1 5.6 0.0018 17.7 3.9 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EDN05404.1 - 0.0008 19.3 0.3 0.0034 17.3 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-RING_UBOX PF13445.1 EDN05404.1 - 0.0029 17.2 3.9 0.0096 15.6 2.7 2.0 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.10 EDN05404.1 - 0.023 14.5 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-Apc11 PF12861.2 EDN05404.1 - 0.23 11.2 2.5 0.8 9.5 1.8 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MBOAT_2 PF13813.1 EDN05405.1 - 2.9e-22 78.5 4.2 2.9e-22 78.5 2.9 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MHYT PF03707.11 EDN05405.1 - 0.084 12.9 4.0 0.22 11.6 2.8 1.7 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat RIX1 PF08167.7 EDN05406.1 - 1.8e-54 183.8 0.6 5e-54 182.4 0.4 1.8 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis Terminase_6 PF03237.10 EDN05406.1 - 0.096 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family TPR_8 PF13181.1 EDN05407.1 - 4.3e-08 32.3 0.4 0.00019 20.9 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDN05407.1 - 7.8e-06 25.4 15.3 0.16 11.9 0.1 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDN05407.1 - 3.1e-05 23.5 10.5 0.027 14.1 0.0 4.9 5 0 0 5 5 5 2 TPR repeat TPR_14 PF13428.1 EDN05407.1 - 6.9e-05 23.1 24.0 0.44 11.3 0.1 7.6 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDN05407.1 - 0.00053 19.9 1.7 0.53 10.6 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN05407.1 - 0.0039 17.5 15.5 0.018 15.3 0.1 4.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDN05407.1 - 0.028 14.3 10.4 5.1 7.1 0.2 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EDN05407.1 - 0.23 11.3 3.1 27 4.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDN05407.1 - 3.5 7.4 11.0 9.3 6.0 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat NDUFA12 PF05071.11 EDN05408.1 - 5.4e-27 94.3 1.3 7.2e-27 93.9 0.9 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 LTV PF04180.9 EDN05410.1 - 1.8e-47 162.8 1.7 2e-38 133.0 0.1 2.2 1 1 1 2 2 2 2 Low temperature viability protein MMR_HSR1 PF01926.18 EDN05412.1 - 1e-09 38.3 0.0 2.2e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EDN05412.1 - 4.7e-05 22.7 0.8 0.01 15.1 0.1 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B cobW PF02492.14 EDN05412.1 - 0.016 14.6 0.9 0.041 13.3 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EDN05412.1 - 0.018 14.8 0.1 0.44 10.3 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AIG1 PF04548.11 EDN05412.1 - 0.044 12.8 0.0 0.087 11.9 0.0 1.5 1 0 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.22 EDN05412.1 - 0.06 12.7 0.1 0.91 8.9 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain zf-C2H2_4 PF13894.1 EDN05413.1 - 0.027 14.7 14.8 0.91 10.0 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN05413.1 - 0.07 13.5 0.4 0.07 13.5 0.3 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type Pkinase PF00069.20 EDN05416.1 - 9.6e-66 221.5 0.0 2e-65 220.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05416.1 - 3.3e-48 164.0 0.0 8e-48 162.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EDN05416.1 - 1.9e-30 104.8 0.0 3.7e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 EDN05416.1 - 6.5e-16 58.2 0.2 1.4e-15 57.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EDN05416.1 - 2.9e-13 49.4 0.1 6.2e-13 48.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EDN05416.1 - 7.1e-08 31.7 0.0 0.00042 19.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like DUF1221 PF06760.6 EDN05416.1 - 0.0071 15.6 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1221) Kdo PF06293.9 EDN05416.1 - 0.067 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L5_C PF00673.16 EDN05417.1 - 3.7e-26 90.6 0.0 6.7e-26 89.8 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus UCH_1 PF13423.1 EDN05418.1 - 4e-95 318.6 0.0 7.2e-95 317.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pep3_Vps18 PF05131.9 EDN05419.1 - 4e-48 162.5 0.0 1.4e-47 160.7 0.0 1.9 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EDN05419.1 - 8.2e-08 31.9 7.6 0.00057 19.5 0.1 3.9 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EDN05419.1 - 0.0003 20.5 0.2 0.00083 19.1 0.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EDN05419.1 - 0.0013 18.4 0.3 0.0034 17.0 0.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain TPR_19 PF14559.1 EDN05419.1 - 0.055 13.8 0.1 1.3 9.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps39_2 PF10367.4 EDN05419.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DUF2175 PF09943.4 EDN05419.1 - 0.1 12.6 0.1 0.31 11.1 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) PspA_IM30 PF04012.7 EDN05419.1 - 0.1 11.9 0.1 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 PspA/IM30 family zf-C3HC4_2 PF13923.1 EDN05419.1 - 0.24 11.4 0.9 0.59 10.2 0.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RVT_1 PF00078.22 EDN05423.1 - 5.3e-25 88.0 0.0 7.9e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN05423.1 - 1e-14 55.0 0.0 1.7e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 RNase H DDE_Tnp_1_7 PF13843.1 EDN05424.1 - 1.9e-16 60.1 1.9 6.9e-08 31.9 0.6 2.1 1 1 1 2 2 2 2 Transposase IS4 RVT_1 PF00078.22 EDN05425.1 - 1.4e-27 96.4 0.0 2.3e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN05425.1 - 1.4e-14 54.5 0.0 3.5e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 RNase H Myb_DNA-bind_6 PF13921.1 EDN05426.1 - 0.0029 17.6 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pkinase PF00069.20 EDN05427.1 - 2e-06 27.1 0.0 2.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain FTA2 PF13095.1 EDN05427.1 - 0.0037 16.8 0.0 0.0067 16.0 0.0 1.4 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.18 EDN05427.1 - 0.0067 16.1 0.0 1.4 8.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDN05427.1 - 0.035 12.9 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2788 PF10981.3 EDN05428.1 - 0.15 11.8 0.0 0.51 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2788) Cytochrom_C552 PF02335.10 EDN05429.1 - 0.0032 16.2 0.1 0.004 15.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c552 Zn_clus PF00172.13 EDN05431.1 - 9.4e-08 31.8 8.7 9.4e-08 31.8 6.0 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 7TMR-DISM_7TM PF07695.6 EDN05431.1 - 1 9.0 11.2 0.18 11.4 0.9 2.8 2 1 0 3 3 3 0 7TM diverse intracellular signalling Lac_bphage_repr PF06543.7 EDN05433.1 - 0.047 13.2 1.3 0.12 11.9 0.9 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor RVT_1 PF00078.22 EDN05434.1 - 0.0043 16.4 0.0 0.0075 15.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN05434.1 - 0.0056 16.2 0.3 0.019 14.6 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN05435.1 - 4.2e-15 56.2 0.0 6.6e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN05435.1 - 0.074 12.8 0.1 0.28 10.9 0.1 2.0 1 1 0 1 1 1 0 Reverse transcriptase-like Myb_DNA-binding PF00249.26 EDN05436.1 - 9.5e-05 22.3 0.1 0.00019 21.3 0.1 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain DUF573 PF04504.9 EDN05436.1 - 0.00024 21.3 1.0 0.00062 20.0 0.7 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF573 Myb_DNA-bind_6 PF13921.1 EDN05436.1 - 0.0008 19.4 0.2 0.0013 18.7 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDN05436.1 - 0.0049 16.9 2.6 0.09 12.9 1.8 2.2 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain RVT_thumb PF06817.9 EDN05439.1 - 0.031 13.8 0.1 0.096 12.2 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase thumb domain DnaJ PF00226.26 EDN05441.1 - 4.8e-22 77.4 1.4 4.8e-22 77.4 1.0 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.1 EDN05441.1 - 0.00018 21.7 2.1 0.00055 20.2 1.4 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDN05441.1 - 0.00044 19.7 2.4 0.007 15.9 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDN05441.1 - 0.00049 19.6 3.7 0.014 15.0 0.4 2.9 2 1 2 4 4 4 2 TPR repeat TPR_17 PF13431.1 EDN05441.1 - 0.0062 16.6 0.3 0.26 11.5 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDN05441.1 - 0.007 16.1 0.1 0.14 12.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN05441.1 - 0.019 15.5 0.1 4.5 8.1 0.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDN05441.1 - 0.022 14.5 4.8 0.17 11.7 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDN05441.1 - 0.17 11.7 1.3 23 5.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EDN05441.1 - 5.1 7.3 8.3 1.5 9.0 0.4 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RF-1 PF00472.15 EDN05442.1 - 2e-33 114.5 0.7 3.6e-33 113.7 0.5 1.4 1 0 0 1 1 1 1 RF-1 domain Mito_carr PF00153.22 EDN05443.1 - 1.5e-33 114.3 0.6 1.3e-21 76.1 0.2 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein AgrB PF04647.10 EDN05443.1 - 0.036 13.1 0.1 0.052 12.6 0.1 1.3 1 1 0 1 1 1 0 Accessory gene regulator B ECR1_N PF14382.1 EDN05443.1 - 0.071 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region DEAD PF00270.24 EDN05444.1 - 2.9e-42 144.0 0.1 4.7e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN05444.1 - 7e-24 83.4 0.1 1.6e-23 82.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EDN05444.1 - 0.034 13.2 0.0 0.08 12.0 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit COX14 PF14880.1 EDN05444.1 - 4.4 7.0 4.7 0.7 9.5 0.1 1.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly RVT_1 PF00078.22 EDN05445.1 - 9e-33 113.4 0.0 1.9e-32 112.4 0.0 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN05445.1 - 3.1e-15 55.8 0.0 2e-14 53.2 0.0 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.18 EDN05445.1 - 0.00039 20.2 4.1 0.00039 20.2 2.9 2.4 2 0 0 2 2 2 1 Zinc knuckle Exo_endo_phos PF03372.18 EDN05445.1 - 0.0005 20.0 0.0 0.00084 19.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF837 PF05769.6 EDN05445.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF837) zf-CCHC_4 PF14392.1 EDN05445.1 - 0.48 10.1 12.8 2.3 7.9 1.0 2.7 1 1 1 2 2 2 0 Zinc knuckle DUF3435 PF11917.3 EDN05446.1 - 1.2e-39 136.2 0.0 1.8e-38 132.3 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) RNase_H PF00075.19 EDN05447.1 - 6.3e-09 36.2 0.0 1.3e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN05447.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like DUF1021 PF06257.6 EDN05449.1 - 0.12 12.0 0.2 0.2 11.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1021) FlxA PF14282.1 EDN05453.1 - 0.011 15.7 3.5 0.13 12.1 2.5 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF1409 PF07197.7 EDN05453.1 - 3 7.9 6.1 5.3 7.1 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1409) RVP_2 PF08284.6 EDN05454.1 - 0.027 14.3 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Gly_transf_sug PF04488.10 EDN05456.1 - 2.6e-05 24.5 0.1 4.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EDN05456.1 - 0.0037 16.4 0.0 0.0051 16.0 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein p450 PF00067.17 EDN05457.1 - 0.028 12.9 0.0 0.028 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 CHCH PF06747.8 EDN05458.1 - 0.086 12.7 0.8 0.13 12.1 0.5 1.3 1 0 0 1 1 1 0 CHCH domain RVT_2 PF07727.9 EDN05459.1 - 1.3e-15 57.0 0.0 1.9e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Flavodoxin_1 PF00258.20 EDN05462.1 - 1.6e-27 96.2 0.0 2.5e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.12 EDN05462.1 - 1.9e-14 52.9 0.0 4.6e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain DDE_Tnp_1_7 PF13843.1 EDN05463.1 - 1.2e-27 96.8 0.0 1.3e-15 57.2 0.0 2.0 1 1 1 2 2 2 2 Transposase IS4 RNase_H PF00075.19 EDN05465.1 - 4.4e-10 40.0 0.0 7e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN05465.1 - 0.044 13.5 0.1 0.18 11.6 0.1 2.0 1 1 0 1 1 1 0 Reverse transcriptase-like Chromo PF00385.19 EDN05466.1 - 4.6e-06 26.2 0.4 8.7e-06 25.3 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA PF00004.24 EDN05468.1 - 9.4e-17 61.4 0.0 1e-15 58.0 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 EDN05468.1 - 2.4e-12 46.8 1.5 3.9e-12 46.1 1.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA_17 PF13207.1 EDN05468.1 - 6.1e-06 27.0 0.1 3.9e-05 24.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDN05468.1 - 0.00057 19.0 0.0 0.002 17.2 0.0 1.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EDN05468.1 - 0.00084 19.6 0.0 0.0043 17.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDN05468.1 - 0.0017 18.1 0.0 0.0044 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN05468.1 - 0.002 18.2 0.0 0.0065 16.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDN05468.1 - 0.0021 17.9 0.1 0.007 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN05468.1 - 0.0023 17.9 0.3 0.011 15.6 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 EDN05468.1 - 0.0026 17.7 0.1 0.0087 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EDN05468.1 - 0.0039 15.9 0.0 0.0079 14.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 EDN05468.1 - 0.0049 16.2 0.0 0.0086 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EDN05468.1 - 0.011 15.2 0.0 0.027 13.8 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein DUF815 PF05673.8 EDN05468.1 - 0.014 14.3 0.0 0.034 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 EDN05468.1 - 0.025 14.3 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Vac_ImportDeg PF09783.4 EDN05468.1 - 0.025 14.0 0.4 0.045 13.2 0.3 1.3 1 0 0 1 1 1 0 Vacuolar import and degradation protein Zeta_toxin PF06414.7 EDN05468.1 - 0.031 13.3 0.0 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 EDN05468.1 - 0.039 13.1 0.1 0.21 10.7 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EDN05468.1 - 0.039 14.2 0.1 0.12 12.6 0.1 2.0 1 1 0 1 1 1 0 ABC transporter DHBP_synthase PF00926.14 EDN05468.1 - 0.078 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 3,4-dihydroxy-2-butanone 4-phosphate synthase RNA_helicase PF00910.17 EDN05468.1 - 0.13 12.4 0.1 0.37 10.9 0.0 1.9 1 1 0 1 1 1 0 RNA helicase DUF1664 PF07889.7 EDN05470.1 - 0.013 15.2 0.7 0.047 13.5 0.2 2.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2783 PF10932.3 EDN05470.1 - 0.015 14.8 0.2 0.032 13.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2783) DUF869 PF05911.6 EDN05470.1 - 0.061 11.5 1.6 0.052 11.7 0.2 1.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) Syntaxin-6_N PF09177.6 EDN05470.1 - 0.13 12.6 0.6 0.74 10.2 0.1 2.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.2 EDN05470.1 - 0.13 12.0 0.2 0.13 12.0 0.1 1.6 2 0 0 2 2 2 0 Tropomyosin like Surfac_D-trimer PF09006.6 EDN05470.1 - 0.24 11.1 1.0 6.6 6.5 0.2 2.5 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Spectrin PF00435.16 EDN05470.1 - 0.24 11.7 2.9 2 8.7 0.1 2.3 2 1 0 2 2 2 0 Spectrin repeat HR1 PF02185.11 EDN05470.1 - 0.28 10.9 3.0 16 5.3 0.1 3.0 2 1 0 3 3 3 0 Hr1 repeat RVT_1 PF00078.22 EDN05471.1 - 2.2e-27 95.8 0.0 5.4e-27 94.5 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN05471.1 - 2.4e-15 57.0 0.1 1e-14 55.0 0.0 2.2 2 0 0 2 2 2 1 RNase H RVT_3 PF13456.1 EDN05471.1 - 0.13 12.1 0.1 1 9.2 0.0 2.3 1 1 0 1 1 1 0 Reverse transcriptase-like Exo_endo_phos_2 PF14529.1 EDN05472.1 - 5.4e-10 38.9 0.0 1.3e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN05472.1 - 0.007 16.3 0.0 0.0089 15.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HTH_33 PF13592.1 EDN05473.1 - 1.6e-06 27.5 0.0 3.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_29 PF13551.1 EDN05473.1 - 0.0001 22.3 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EDN05473.1 - 0.0013 18.3 0.9 0.094 12.4 0.1 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EDN05473.1 - 0.0056 17.4 0.0 0.012 16.4 0.0 1.5 1 1 1 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EDN05473.1 - 0.018 14.9 0.3 0.059 13.2 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Tnp_IS630 PF01710.11 EDN05473.1 - 0.037 13.7 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Transposase HTH_28 PF13518.1 EDN05473.1 - 0.062 13.3 0.0 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain PAX PF00292.13 EDN05473.1 - 0.075 12.7 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 'Paired box' domain HALZ PF02183.13 EDN05474.1 - 2.3e-05 24.0 0.6 4e-05 23.2 0.4 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper ATG16 PF08614.6 EDN05474.1 - 0.0028 17.5 0.5 0.0049 16.7 0.3 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Kinesin-relat_1 PF12711.2 EDN05474.1 - 0.013 15.9 0.0 0.04 14.3 0.1 1.7 2 0 0 2 2 2 0 Kinesin motor ADIP PF11559.3 EDN05474.1 - 0.028 14.3 1.4 0.09 12.6 0.6 1.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EDN05474.1 - 0.033 14.5 0.2 0.11 12.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 EDN05474.1 - 0.076 12.9 0.4 0.16 11.9 0.3 1.5 1 0 0 1 1 1 0 bZIP transcription factor DUF2216 PF10226.4 EDN05474.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) TSC22 PF01166.13 EDN05474.1 - 0.2 11.6 0.6 0.65 10.0 0.4 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family Mpp10 PF04006.7 EDN05475.1 - 1.3e-08 33.7 25.0 1.1e-06 27.4 17.4 2.0 1 1 0 1 1 1 1 Mpp10 protein SPX PF03105.14 EDN05477.1 - 1.8e-22 80.4 5.8 2.6e-14 53.6 1.3 2.4 1 1 1 2 2 2 2 SPX domain Rep-A_N PF04057.7 EDN05478.1 - 0.03 14.0 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain Tho2 PF11262.3 EDN05478.1 - 0.071 12.1 0.1 0.072 12.1 0.1 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CFIA_Pcf11 PF11526.3 EDN05481.1 - 7.1e-05 22.8 1.1 0.00018 21.5 0.7 1.7 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 zf-ISL3 PF14690.1 EDN05481.1 - 0.026 14.5 1.0 0.026 14.5 0.7 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-CCHC_4 PF14392.1 EDN05481.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle RRN7 PF11781.3 EDN05481.1 - 0.46 10.0 2.8 0.6 9.6 0.2 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 PAT1 PF09770.4 EDN05481.1 - 3.2 5.8 17.7 3.7 5.6 12.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GFO_IDH_MocA PF01408.17 EDN05482.1 - 3e-06 27.7 0.0 3.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ADK PF00406.17 EDN05485.1 - 6.7e-61 204.5 0.1 8.4e-61 204.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EDN05485.1 - 1.2e-14 53.6 0.0 3e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EDN05485.1 - 0.00013 21.8 0.0 0.00026 20.8 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN05485.1 - 0.0002 22.1 0.0 0.00058 20.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EDN05485.1 - 0.005 15.9 0.1 0.011 14.8 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EDN05485.1 - 0.0056 16.9 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain JAB PF01398.16 EDN05486.1 - 7.8e-28 96.5 0.0 2.2e-27 95.0 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EDN05486.1 - 3.3e-21 75.4 0.3 8.9e-21 74.1 0.1 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Thioesterase PF00975.15 EDN05486.1 - 0.033 14.4 0.1 2.1 8.5 0.2 2.3 1 1 1 2 2 2 0 Thioesterase domain AMP-binding PF00501.23 EDN05488.1 - 3.3e-73 246.4 0.0 5.3e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EDN05488.1 - 1.4e-67 227.2 0.0 2.6e-67 226.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EDN05488.1 - 1.1e-11 44.6 0.0 2.4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EDN05488.1 - 5.1e-10 40.1 0.0 7.1e-09 36.4 0.0 2.9 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EDN05488.1 - 5.5e-10 39.3 0.0 1.2e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EDN05488.1 - 1.7e-07 30.2 0.0 3.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EDN05488.1 - 0.058 12.2 0.0 0.78 8.5 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EDN05488.1 - 0.19 10.6 0.0 0.41 9.4 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CAP_GLY PF01302.20 EDN05489.1 - 3.1e-29 100.4 0.0 5.4e-29 99.7 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EDN05489.1 - 5.5e-17 61.8 0.0 9.7e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EDN05489.1 - 6.6e-06 25.4 1.5 1.1e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EDN05489.1 - 0.16 11.6 0.5 0.73 9.5 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Pkinase PF00069.20 EDN05491.1 - 2.9e-70 236.3 0.0 1.2e-59 201.5 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05491.1 - 2e-31 109.0 0.0 9.5e-28 96.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDN05491.1 - 0.00012 21.1 0.0 0.0002 20.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN05491.1 - 0.00032 20.5 0.6 0.69 9.6 0.1 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EDN05491.1 - 0.019 14.0 0.2 1.5 7.8 0.1 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SNF2_N PF00176.18 EDN05492.1 - 4.9e-16 58.3 0.4 6.4e-16 58.0 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Host_attach PF10116.4 EDN05492.1 - 0.03 14.5 0.1 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein required for attachment to host cells Myb_DNA-binding PF00249.26 EDN05493.1 - 0.00013 21.9 0.1 0.00025 21.0 0.1 1.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain DUF573 PF04504.9 EDN05493.1 - 0.00028 21.0 0.9 0.00086 19.5 0.7 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF573 Myb_DNA-bind_6 PF13921.1 EDN05493.1 - 0.0011 19.0 0.2 0.0019 18.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDN05493.1 - 0.0064 16.6 2.4 0.11 12.6 1.6 2.2 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Retrotrans_gag PF03732.12 EDN05496.1 - 8.6e-06 25.7 1.4 8.6e-06 25.7 1.0 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein CobA_CobO_BtuR PF02572.10 EDN05496.1 - 0.12 11.9 0.2 0.36 10.4 0.1 1.7 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP His_Phos_1 PF00300.17 EDN05496.1 - 0.12 12.4 0.6 0.17 11.9 0.4 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Colicin-DNase PF12639.2 EDN05496.1 - 0.27 11.4 1.5 2.7 8.2 0.0 2.3 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin Helicase_C PF00271.26 EDN05497.1 - 2e-12 46.8 0.0 4.9e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3505 PF12013.3 EDN05497.1 - 7.9e-06 26.0 0.4 4e-05 23.8 0.3 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) KH_3 PF13014.1 EDN05499.1 - 0.013 15.1 1.6 0.66 9.6 0.1 2.2 2 0 0 2 2 2 0 KH domain KH_1 PF00013.24 EDN05499.1 - 0.12 12.0 0.6 9.9 5.8 0.0 2.1 2 0 0 2 2 2 0 KH domain DUF3505 PF12013.3 EDN05500.1 - 5.2e-38 129.6 5.5 5.2e-38 129.6 3.8 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3505) DUF2200 PF09966.4 EDN05502.1 - 0.1 12.4 1.8 42 4.0 0.0 4.3 3 1 2 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2200) Myb_DNA-binding PF00249.26 EDN05503.1 - 0.00053 19.9 0.1 0.0011 18.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF573 PF04504.9 EDN05503.1 - 0.0013 18.9 0.7 0.0043 17.2 0.5 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF573 Myb_DNA-bind_6 PF13921.1 EDN05503.1 - 0.0054 16.8 1.4 0.0089 16.1 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDN05503.1 - 0.034 14.2 2.2 0.48 10.5 1.5 2.5 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF3505 PF12013.3 EDN05506.1 - 2.8e-38 130.5 5.5 2.8e-38 130.5 3.8 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) Borrelia_P83 PF05262.6 EDN05506.1 - 4.7 5.3 9.3 2.3 6.3 1.5 2.0 2 0 0 2 2 2 0 Borrelia P83/100 protein Pribosyltran PF00156.22 EDN05509.1 - 1.7e-17 63.3 0.0 2.3e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EDN05509.1 - 0.017 14.3 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_3 PF15610.1 EDN05509.1 - 0.035 13.0 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 PRTase ComF-like Nol1_Nop2_Fmu PF01189.12 EDN05510.1 - 1.4e-12 47.5 0.0 4.9e-06 26.1 0.0 3.0 3 0 0 3 3 3 2 NOL1/NOP2/sun family Ferric_reduct PF01794.14 EDN05511.1 - 0.00077 19.5 3.5 0.00077 19.5 2.4 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF998 PF06197.8 EDN05511.1 - 0.14 11.5 12.9 0.3 10.3 8.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF998) DUF4405 PF14358.1 EDN05511.1 - 1.9 8.7 9.6 0.21 11.7 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Pkinase PF00069.20 EDN05513.1 - 2.7e-17 62.7 0.9 4.3e-16 58.8 0.6 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05513.1 - 2.3e-09 36.7 0.0 3.4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDN05513.1 - 0.014 14.4 0.1 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EDN05513.1 - 0.016 14.0 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EDN05513.1 - 0.035 13.8 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EDN05513.1 - 0.094 12.0 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 RIO1 family DDE_1 PF03184.14 EDN05516.1 - 8.6e-37 126.3 0.0 1.7e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN05516.1 - 2.4e-05 24.0 0.0 7.4e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN05516.1 - 0.0067 15.9 0.6 0.0067 15.9 0.4 2.2 2 0 0 2 2 2 1 helix-turn-helix, Psq domain DUF2229 PF09989.4 EDN05516.1 - 0.48 9.8 5.9 3.7 6.9 4.0 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Borrelia_P83 PF05262.6 EDN05516.1 - 1.7 6.8 19.8 2.8 6.0 13.7 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein TraG_N PF07916.6 EDN05516.1 - 1.7 6.9 3.4 2.6 6.3 2.3 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region FAA_hydrolase PF01557.13 EDN05517.1 - 1.8e-47 161.6 0.0 2.4e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EDN05517.1 - 4.5e-24 84.5 0.0 8.2e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal GST_N_2 PF13409.1 EDN05518.1 - 9.1e-11 41.6 0.0 2.4e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EDN05518.1 - 8e-10 38.8 0.1 2.1e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EDN05518.1 - 3.6e-06 26.8 0.0 7.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EDN05518.1 - 5.9e-05 23.1 0.0 0.00031 20.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDN05518.1 - 0.00012 21.9 0.2 0.00025 20.8 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HAD PF12710.2 EDN05519.1 - 1.2e-15 58.1 0.0 1.6e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDN05519.1 - 8.3e-11 42.7 0.0 8.2e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDN05519.1 - 1.2e-09 38.1 0.0 1.5e-07 31.3 0.1 2.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EDN05519.1 - 5.5e-08 33.2 0.0 1.1e-06 28.9 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EDN05519.1 - 4.3e-05 22.7 0.0 0.0054 15.9 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase DUF705 PF05152.7 EDN05519.1 - 0.0012 17.9 0.2 0.0018 17.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) S6PP PF05116.8 EDN05519.1 - 0.022 14.0 0.1 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase RVT_2 PF07727.9 EDN05520.1 - 8.2e-59 198.5 0.0 1.2e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Semialdhyde_dhC PF02774.13 EDN05521.1 - 1.9e-32 112.6 0.0 2.9e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EDN05521.1 - 6.9e-25 87.6 0.0 1.2e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EDN05521.1 - 0.042 13.7 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GCV_T PF01571.16 EDN05522.1 - 2.2e-52 177.5 0.0 2.9e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EDN05522.1 - 5.6e-17 61.5 0.2 9.5e-17 60.8 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Glyco_hydro_71 PF03659.9 EDN05523.1 - 2.8e-155 516.5 1.8 3.2e-155 516.3 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 hGDE_central PF14702.1 EDN05523.1 - 0.067 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 central domain of human glycogen debranching enzyme GCR1_C PF12550.3 EDN05524.1 - 5.3e-23 80.6 0.4 1.7e-22 79.0 0.1 2.0 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes DUF3716 PF12511.3 EDN05524.1 - 1.7e-08 33.9 9.4 1.7e-08 33.9 6.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3716) BTB_2 PF02214.17 EDN05525.1 - 0.13 12.4 0.0 0.78 9.9 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain EF-hand_7 PF13499.1 EDN05526.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.8 1 1 0 1 1 1 0 EF-hand domain pair SAP18 PF06487.7 EDN05528.1 - 2.7e-47 159.5 0.0 3.4e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.10 EDN05529.1 - 2.1e-54 183.3 0.0 2.1e-54 183.3 0.0 2.0 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EDN05529.1 - 9.5e-12 43.9 0.5 9.5e-12 43.9 0.4 2.7 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like CAF-1_p150 PF11600.3 EDN05529.1 - 5.4 6.3 30.0 9.8 5.4 20.8 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pyr_redox_3 PF13738.1 EDN05530.1 - 3e-06 27.4 0.0 2.4e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN05530.1 - 0.0043 16.8 0.0 0.041 13.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Arf PF00025.16 EDN05531.1 - 1.1e-29 102.9 0.0 8.8e-17 60.8 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EDN05531.1 - 6.5e-06 25.0 0.0 1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit Ras PF00071.17 EDN05531.1 - 3.8e-05 23.1 0.0 0.039 13.3 0.0 2.2 2 0 0 2 2 2 2 Ras family GTP_EFTU PF00009.22 EDN05531.1 - 4.3e-05 23.0 0.0 6.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EDN05531.1 - 0.00068 20.1 0.0 0.0094 16.4 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EDN05531.1 - 0.003 16.7 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PIGA PF08288.7 EDN05532.1 - 2.5e-47 159.1 4.4 5e-47 158.2 1.1 2.3 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EDN05532.1 - 3.9e-30 104.5 0.0 5.9e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EDN05532.1 - 6.4e-18 65.2 0.0 1.1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EDN05532.1 - 5.9e-17 61.9 0.5 1.2e-16 60.9 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EDN05532.1 - 1.9e-13 50.8 0.0 3.1e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EDN05532.1 - 8.9e-06 25.5 0.3 1.7e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EDN05532.1 - 0.00052 20.2 0.0 0.0014 18.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 DEAD PF00270.24 EDN05533.1 - 8.4e-32 109.9 0.0 3.9e-15 55.7 0.0 2.9 2 1 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN05533.1 - 2.1e-18 65.9 0.1 4.2e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN05533.1 - 9.6e-08 32.0 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PT PF04886.7 EDN05534.1 - 1.8e-08 33.5 37.8 1.5e-06 27.4 9.8 8.9 5 2 3 8 8 8 2 PT repeat Asp_decarbox PF02261.11 EDN05535.1 - 0.074 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Aspartate decarboxylase Kelch_5 PF13854.1 EDN05536.1 - 7.1e-14 51.3 3.3 7.1e-14 51.3 2.3 3.2 4 0 0 4 4 4 1 Kelch motif SpoA PF01052.15 EDN05536.1 - 0.041 13.4 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) Kelch_6 PF13964.1 EDN05536.1 - 0.064 13.4 3.0 0.3 11.3 0.3 3.0 3 0 0 3 3 3 0 Kelch motif DUF865 PF05906.6 EDN05537.1 - 0.52 9.9 2.5 0.91 9.1 1.7 1.4 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) GMC_oxred_N PF00732.14 EDN05538.1 - 6.7e-27 94.4 3.7 1.4e-21 76.9 0.1 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN05538.1 - 2.9e-25 89.2 0.6 7.9e-25 87.8 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EDN05538.1 - 4.7e-08 32.3 0.4 0.0086 15.0 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDN05538.1 - 4.3e-07 29.1 0.1 7e-06 25.1 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EDN05538.1 - 9.5e-06 25.6 0.2 0.0004 20.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN05538.1 - 0.0011 19.0 0.4 0.014 15.3 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDN05538.1 - 0.0081 15.2 0.2 0.024 13.7 0.1 1.7 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EDN05538.1 - 0.029 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EDN05538.1 - 0.064 11.7 0.4 0.15 10.5 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.2 EDN05538.1 - 0.13 11.3 0.9 0.19 10.7 0.6 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FA_hydroxylase PF04116.8 EDN05539.1 - 4.8e-16 59.1 12.5 4.8e-16 59.1 8.7 2.3 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily TCTP PF00838.12 EDN05540.1 - 1.1e-33 116.6 0.0 1.4e-23 83.7 0.0 2.2 2 0 0 2 2 2 2 Translationally controlled tumour protein FliE PF02049.13 EDN05540.1 - 0.033 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE Sod_Fe_N PF00081.17 EDN05540.1 - 0.12 12.7 0.2 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain HTH_16 PF12645.2 EDN05540.1 - 0.14 12.1 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Fungal_trans PF04082.13 EDN05541.1 - 8e-16 57.6 0.0 1.6e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN05541.1 - 1e-08 34.9 10.1 2e-08 34.0 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SRP19 PF01922.12 EDN05542.1 - 1e-30 106.1 0.0 1.6e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Mtc PF03820.12 EDN05543.1 - 1.7e-102 342.2 0.0 3.3e-102 341.2 0.0 1.4 1 1 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.20 EDN05546.1 - 1.1e-55 188.5 0.0 1.8e-55 187.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05546.1 - 7.3e-19 67.8 0.0 3.5e-18 65.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EDN05546.1 - 0.075 12.6 0.1 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase SF3a60_bindingd PF12108.3 EDN05546.1 - 0.083 12.4 0.9 5.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain TAF4 PF05236.9 EDN05548.1 - 4.1e-17 62.3 0.1 2.4e-05 23.7 0.0 3.3 3 0 0 3 3 3 3 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.3 EDN05549.1 - 2.6e-72 242.7 0.0 1.2e-68 230.6 0.0 2.3 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EDN05549.1 - 4e-32 110.8 0.0 9e-32 109.6 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EDN05549.1 - 9.1e-17 61.3 0.1 2e-16 60.2 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EDN05549.1 - 1.2e-12 47.7 0.4 2.3e-12 46.8 0.3 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EDN05549.1 - 8.6e-07 28.6 0.1 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EDN05549.1 - 1.7e-05 24.5 0.1 4e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PHD PF00628.24 EDN05550.1 - 0.0018 17.8 1.7 0.0034 17.0 1.2 1.4 1 0 0 1 1 1 1 PHD-finger DUF2293 PF10056.4 EDN05551.1 - 1.5e-28 98.5 0.1 2.9e-28 97.6 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) BTB PF00651.26 EDN05552.1 - 3e-14 52.9 0.3 1.2e-13 50.9 0.1 2.2 2 1 0 2 2 2 1 BTB/POZ domain FcoT PF10862.3 EDN05552.1 - 0.036 13.6 0.2 0.1 12.1 0.2 1.8 1 0 0 1 1 1 0 FcoT-like thioesterase domain DUF1662 PF07878.6 EDN05552.1 - 0.096 12.4 0.2 24 4.7 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1662) Rho_Binding PF08912.6 EDN05552.1 - 0.12 12.6 0.8 0.35 11.1 0.6 1.7 1 0 0 1 1 1 0 Rho Binding RPE65 PF03055.10 EDN05553.1 - 5.6e-120 401.1 0.0 6.6e-120 400.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Dynamin_N PF00350.18 EDN05553.1 - 0.028 14.2 0.0 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Acetyltransf_1 PF00583.19 EDN05554.1 - 1.4e-10 41.0 0.0 3.8e-10 39.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN05554.1 - 3.2e-06 27.2 0.0 2.9e-05 24.1 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDN05554.1 - 0.001 19.1 0.0 0.0036 17.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDN05554.1 - 0.002 17.9 0.0 0.027 14.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain P12 PF12669.2 EDN05555.1 - 0.42 10.8 5.5 0.38 10.9 2.5 1.9 2 0 0 2 2 2 0 Virus attachment protein p12 family TruD PF01142.13 EDN05556.1 - 1.2e-55 188.6 0.0 1.3e-51 175.5 0.0 3.8 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) GMP_synt_C PF00958.17 EDN05557.1 - 8.5e-39 131.1 0.0 3.5e-38 129.2 0.0 2.0 2 0 0 2 2 2 1 GMP synthase C terminal domain GATase PF00117.23 EDN05557.1 - 2.7e-37 128.1 0.0 5.3e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EDN05557.1 - 1.8e-12 46.6 0.2 6.3e-07 28.5 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EDN05557.1 - 6.7e-08 32.2 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.8 EDN05557.1 - 0.00027 20.2 0.0 0.0013 18.1 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EDN05557.1 - 0.00066 18.3 0.1 0.0027 16.3 0.0 1.9 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 EDN05557.1 - 0.00085 18.8 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 EDN05557.1 - 0.00094 18.6 0.0 0.007 15.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 EDN05557.1 - 0.0081 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.14 EDN05557.1 - 0.018 14.1 0.1 0.038 13.0 0.0 1.5 2 0 0 2 2 2 0 Arginosuccinate synthase ATP_bind_3 PF01171.15 EDN05557.1 - 0.067 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 PP-loop family DDE_Tnp_1_7 PF13843.1 EDN05560.1 - 7.4e-32 110.7 0.1 9.8e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 RVT_1 PF00078.22 EDN05561.1 - 2.8e-35 121.6 0.0 4.2e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1814 PF08843.6 EDN05563.1 - 0.00048 19.9 0.0 0.015 15.0 0.0 2.1 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) NTP_transf_5 PF14907.1 EDN05563.1 - 0.0027 17.1 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase DUF2204 PF09970.4 EDN05563.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.5 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF2204) FANCI_S2 PF14676.1 EDN05564.1 - 0.018 14.9 0.1 0.022 14.6 0.1 1.1 1 0 0 1 1 1 0 FANCI solenoid 2 Phage_holin_1 PF04531.8 EDN05564.1 - 0.063 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin UPF0302 PF08864.5 EDN05564.1 - 0.076 12.8 0.3 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 UPF0302 domain Med10 PF09748.4 EDN05564.1 - 0.11 12.3 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex DDE_Tnp_1_7 PF13843.1 EDN05565.1 - 1.4e-31 109.8 0.0 2.5e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 Transposase IS4 ELO PF01151.13 EDN05566.1 - 2.1e-68 230.3 2.4 5.6e-54 183.0 1.6 2.1 2 0 0 2 2 2 2 GNS1/SUR4 family ATP-synt_G PF04718.10 EDN05568.1 - 1.2e-30 106.1 0.1 2.7e-30 105.0 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Helicase_C PF00271.26 EDN05569.1 - 1.1e-22 79.6 0.1 4e-22 77.8 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN05569.1 - 2.2e-08 33.7 0.0 4.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Methyltransf_16 PF10294.4 EDN05570.1 - 2.1e-21 76.1 0.0 4.1e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EDN05570.1 - 0.00016 21.4 0.0 0.00069 19.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN05570.1 - 0.1 13.1 0.0 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 EDN05570.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain VPS28 PF03997.7 EDN05571.1 - 8.3e-62 208.1 0.2 9.7e-62 207.9 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein Imm3 PF14425.1 EDN05571.1 - 0.14 12.0 0.9 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Immunity protein Imm3 GvpG PF05120.7 EDN05571.1 - 0.38 10.5 2.6 4.8 7.0 0.3 2.3 2 0 0 2 2 2 0 Gas vesicle protein G Noc2 PF03715.8 EDN05572.1 - 1.4e-120 401.6 0.0 3e-120 400.6 0.0 1.6 1 0 0 1 1 1 1 Noc2p family MoaC PF01967.16 EDN05573.1 - 2e-42 144.0 3.6 4.1e-20 71.8 1.3 2.4 2 0 0 2 2 2 2 MoaC family Mob_synth_C PF06463.8 EDN05573.1 - 1.4e-35 121.8 0.0 6e-35 119.7 0.0 2.0 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EDN05573.1 - 3.3e-21 76.1 0.0 7.1e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EDN05573.1 - 4.6e-05 23.5 0.0 8.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EDN05573.1 - 0.00089 19.2 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain ABC_tran PF00005.22 EDN05574.1 - 9.5e-35 119.8 4.4 5e-19 68.9 0.0 4.0 3 2 1 4 4 3 3 ABC transporter AAA_21 PF13304.1 EDN05574.1 - 7.7e-15 55.6 9.8 0.0018 18.3 0.0 4.2 3 1 0 4 4 4 4 AAA domain AAA_17 PF13207.1 EDN05574.1 - 6.1e-08 33.5 0.0 0.0022 18.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EDN05574.1 - 1.3e-06 27.8 0.3 0.0096 15.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.1 EDN05574.1 - 1.6e-06 28.1 0.0 0.0061 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EDN05574.1 - 1.7e-06 27.4 2.4 0.14 11.3 0.1 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EDN05574.1 - 2.4e-06 27.8 0.0 0.023 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EDN05574.1 - 7.9e-06 26.3 3.8 0.091 13.0 1.1 3.1 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 EDN05574.1 - 9.9e-06 26.0 0.0 0.084 13.3 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein ABC_tran_2 PF12848.2 EDN05574.1 - 3.5e-05 23.5 2.7 3.5e-05 23.5 1.9 2.3 2 1 1 3 3 2 1 ABC transporter MMR_HSR1 PF01926.18 EDN05574.1 - 4.1e-05 23.5 0.2 0.12 12.3 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_14 PF13173.1 EDN05574.1 - 4.6e-05 23.3 0.0 0.039 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EDN05574.1 - 8.9e-05 22.7 0.0 0.24 11.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EDN05574.1 - 0.00014 21.4 0.0 0.12 11.7 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 EDN05574.1 - 0.00017 21.3 0.2 0.39 10.4 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 EDN05574.1 - 0.00021 20.4 1.4 0.042 12.9 0.0 3.2 4 0 0 4 4 3 1 AAA ATPase domain AAA_33 PF13671.1 EDN05574.1 - 0.00024 20.9 0.4 0.82 9.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EDN05574.1 - 0.00026 20.2 0.2 0.58 9.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDN05574.1 - 0.00033 20.6 1.4 0.069 13.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EDN05574.1 - 0.00068 19.3 0.3 0.97 9.0 0.2 2.6 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 EDN05574.1 - 0.00082 19.5 3.0 0.52 10.4 0.0 3.4 3 1 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 EDN05574.1 - 0.001 19.2 0.1 0.22 11.6 0.0 2.7 2 1 0 2 2 2 1 RNA helicase AAA_30 PF13604.1 EDN05574.1 - 0.0021 17.6 0.3 0.75 9.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN05574.1 - 0.0021 17.4 0.0 2.7 7.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.12 EDN05574.1 - 0.0041 16.5 0.0 1.8 7.8 0.0 2.7 2 0 0 2 2 2 1 Thymidylate kinase DUF87 PF01935.12 EDN05574.1 - 0.0046 16.8 4.1 1 9.0 0.0 2.8 3 0 0 3 3 2 2 Domain of unknown function DUF87 ArgK PF03308.11 EDN05574.1 - 0.0048 15.7 3.1 1.1 7.9 0.0 3.0 3 0 0 3 3 3 2 ArgK protein Arf PF00025.16 EDN05574.1 - 0.011 15.0 0.2 0.42 9.8 0.1 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.14 EDN05574.1 - 0.011 15.1 1.3 0.42 10.0 0.4 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.1 EDN05574.1 - 0.017 13.6 1.0 3.4 5.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.17 EDN05574.1 - 0.026 13.9 0.0 5.7 6.3 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 EDN05574.1 - 0.029 14.0 0.6 0.61 9.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EDN05574.1 - 0.064 12.1 1.6 5.4 5.7 0.4 2.5 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 EDN05574.1 - 0.065 12.9 0.1 9.9 5.7 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 EDN05574.1 - 0.093 12.1 0.3 3.8 6.8 0.2 2.3 2 0 0 2 2 2 0 AAA-like domain PduV-EutP PF10662.4 EDN05574.1 - 0.095 12.1 0.6 4.2 6.8 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EDN05574.1 - 0.1 12.4 0.3 3.9 7.2 0.0 2.6 2 1 0 2 2 2 0 Dynamin family Pox_A32 PF04665.7 EDN05574.1 - 0.17 11.1 0.8 3 7.0 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein NTPase_1 PF03266.10 EDN05574.1 - 0.29 10.8 3.9 7.7 6.2 0.0 3.2 4 0 0 4 4 2 0 NTPase DUF3584 PF12128.3 EDN05574.1 - 5.7 4.1 9.4 0.12 9.6 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) RNase_H PF00075.19 EDN05577.1 - 0.0022 18.3 0.0 0.0046 17.2 0.0 1.7 1 1 0 1 1 1 1 RNase H DDE_Tnp_1_7 PF13843.1 EDN05578.1 - 4.2e-74 249.6 0.6 3.2e-41 141.5 0.0 2.3 2 0 0 2 2 2 2 Transposase IS4 APH PF01636.18 EDN05578.1 - 9.8e-07 28.7 0.0 0.008 15.9 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family RVT_1 PF00078.22 EDN05580.1 - 1.1e-36 126.1 0.0 1.9e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN05580.1 - 5.9e-15 55.7 0.0 1.8e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN05580.1 - 3e-11 42.9 0.0 8.4e-11 41.5 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase WD40 PF00400.27 EDN05582.1 - 1.2e-08 34.4 0.3 0.069 13.0 0.0 5.7 5 1 0 5 5 5 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EDN05582.1 - 0.00029 20.2 0.0 0.1 12.0 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EDN05582.1 - 0.00083 17.3 0.0 0.0022 15.9 0.0 1.6 2 0 0 2 2 2 1 IKI3 family eIF2A PF08662.6 EDN05582.1 - 0.03 14.0 0.1 0.24 11.0 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EDN05582.1 - 0.13 12.0 2.3 7.9 6.2 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ribosomal_S25 PF03297.10 EDN05583.1 - 1.9e-40 137.1 4.8 2.2e-40 136.9 3.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.2 EDN05583.1 - 0.01 15.4 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 0 MarR family HTH_DeoR PF08220.7 EDN05583.1 - 0.012 15.1 0.1 0.016 14.7 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain FeoC PF09012.5 EDN05583.1 - 0.027 14.1 0.3 0.072 12.8 0.0 1.7 1 1 1 2 2 2 0 FeoC like transcriptional regulator Rrf2 PF02082.15 EDN05583.1 - 0.031 14.3 0.1 0.048 13.7 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_11 PF08279.7 EDN05583.1 - 0.055 13.1 0.1 0.078 12.6 0.1 1.3 1 0 0 1 1 1 0 HTH domain TrmB PF01978.14 EDN05583.1 - 0.071 12.8 0.3 0.091 12.4 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_24 PF13412.1 EDN05583.1 - 0.1 11.9 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cyt-b5 PF00173.23 EDN05584.1 - 2.5e-06 27.1 0.0 3.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1464 PF07318.7 EDN05584.1 - 0.048 12.4 0.0 0.06 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Gtr1_RagA PF04670.7 EDN05585.1 - 9.2e-56 188.5 0.6 1.5e-55 187.8 0.1 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EDN05585.1 - 0.11 11.6 0.1 0.29 10.3 0.1 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family His_Phos_2 PF00328.17 EDN05586.1 - 3.5e-19 69.3 0.0 3.6e-18 66.0 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Methyltransf_23 PF13489.1 EDN05587.1 - 2.1e-21 76.3 0.0 3.8e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN05587.1 - 2.4e-13 50.4 0.0 4.7e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN05587.1 - 5.6e-11 43.0 0.0 1.5e-09 38.3 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN05587.1 - 1.1e-10 41.3 0.0 1.5e-09 37.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN05587.1 - 3e-08 34.0 0.0 3.1e-07 30.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN05587.1 - 9.8e-07 29.0 0.0 4.3e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN05587.1 - 1.6e-06 28.1 0.0 6e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN05587.1 - 4.8e-05 22.5 0.0 0.00033 19.8 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EDN05587.1 - 0.0007 19.0 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 EDN05587.1 - 0.0019 17.2 0.0 0.0087 15.1 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EDN05587.1 - 0.0073 15.7 0.0 0.038 13.3 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase small domain PCMT PF01135.14 EDN05587.1 - 0.021 14.3 0.0 0.046 13.2 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EDN05587.1 - 0.024 13.7 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EDN05587.1 - 0.061 13.3 0.1 0.14 12.1 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.15 EDN05587.1 - 0.077 12.0 0.0 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Aldo_ket_red PF00248.16 EDN05588.1 - 1.1e-37 129.4 0.0 1.4e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Lactamase_B_2 PF12706.2 EDN05589.1 - 2.6e-33 115.2 0.1 4.4e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EDN05589.1 - 3.6e-22 77.6 0.0 1.2e-21 75.9 0.0 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 EDN05589.1 - 6.1e-10 39.0 0.0 2.5e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily FadA PF09403.5 EDN05589.1 - 0.26 11.2 0.7 14 5.7 0.3 2.4 2 0 0 2 2 2 0 Adhesion protein FadA bZIP_1 PF00170.16 EDN05590.1 - 1.1e-09 38.0 10.3 2.6e-09 36.8 7.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EDN05590.1 - 0.00025 20.7 9.6 0.00025 20.7 6.6 2.9 3 0 0 3 3 3 1 Basic region leucine zipper Spt20 PF12090.3 EDN05590.1 - 0.88 8.8 10.4 0.6 9.4 3.6 2.4 2 0 0 2 2 2 0 Spt20 family Dus PF01207.12 EDN05592.1 - 7.9e-56 189.1 0.0 3.5e-55 187.0 0.0 2.0 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EDN05592.1 - 0.0063 15.5 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase MIF PF01187.13 EDN05593.1 - 1.8e-07 31.1 0.1 3.3e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Macro PF01661.16 EDN05594.1 - 2.9e-11 43.2 0.0 2.6e-06 27.3 0.0 2.7 2 1 0 2 2 2 2 Macro domain Mis12 PF05859.7 EDN05596.1 - 1.3e-44 151.5 0.0 1.8e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Mis12 protein FA_desaturase PF00487.19 EDN05597.1 - 0.00062 19.2 0.3 0.00062 19.2 0.2 1.6 2 0 0 2 2 2 1 Fatty acid desaturase Ni_hydr_CYTB PF01292.15 EDN05597.1 - 0.09 12.1 3.5 0.4 10.0 2.5 2.0 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Claudin_2 PF13903.1 EDN05597.1 - 0.64 9.6 10.2 0.31 10.7 1.8 2.6 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF202 PF02656.10 EDN05597.1 - 2.3 8.5 7.4 51 4.1 5.2 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF202) BCNT PF07572.7 EDN05598.1 - 3.3e-28 97.4 0.1 8.5e-28 96.1 0.0 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development DUF1168 PF06658.7 EDN05598.1 - 0.0016 17.9 3.0 0.0016 17.9 2.1 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF1168) zf-C2H2 PF00096.21 EDN05599.1 - 7.4e-08 32.2 7.0 8.8e-05 22.6 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDN05599.1 - 1.5e-07 31.3 2.2 1.5e-07 31.3 1.6 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDN05599.1 - 9.3e-07 28.7 7.7 0.011 16.0 1.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger Spt20 PF12090.3 EDN05600.1 - 2.9e-53 179.9 0.1 2.9e-53 179.9 0.1 4.3 3 1 0 3 3 3 1 Spt20 family Hexapep PF00132.19 EDN05602.1 - 4.7e-10 38.5 1.9 9.4e-05 21.7 0.6 2.7 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EDN05602.1 - 5.1 6.7 12.0 10 5.7 0.7 3.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase MFS_1 PF07690.11 EDN05605.1 - 1.1e-18 67.1 37.3 2.7e-12 46.1 18.0 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN05605.1 - 7.4e-13 47.8 15.8 6.7e-08 31.5 2.9 2.6 1 1 1 2 2 2 2 Sugar (and other) transporter DUF2583 PF10762.4 EDN05605.1 - 1.1 9.4 3.9 2 8.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2583) VanZ PF04892.7 EDN05606.1 - 0.0083 16.0 1.7 0.0083 16.0 1.2 1.9 2 1 0 2 2 2 1 VanZ like family DUF998 PF06197.8 EDN05606.1 - 0.28 10.4 10.8 0.08 12.2 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF998) DUF202 PF02656.10 EDN05606.1 - 4.3 7.6 7.3 12 6.2 0.5 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) PTR2 PF00854.16 EDN05607.1 - 1.1e-40 139.5 12.2 1e-39 136.4 6.7 2.4 2 1 0 2 2 2 1 POT family MFS_1 PF07690.11 EDN05607.1 - 9.7e-09 34.3 20.8 4.8e-06 25.5 6.3 3.0 3 0 0 3 3 3 2 Major Facilitator Superfamily Cation_efflux PF01545.16 EDN05607.1 - 0.016 14.3 0.6 0.16 11.0 0.0 2.2 2 0 0 2 2 2 0 Cation efflux family DUF1435 PF07256.7 EDN05607.1 - 4.4 7.3 6.9 1.2 9.1 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) Glyco_hydro_31 PF01055.21 EDN05608.1 - 2.3e-160 534.2 2.8 5.3e-81 272.6 0.6 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EDN05608.1 - 2.7e-10 39.9 1.2 8.1e-10 38.4 0.8 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like BPL_LplA_LipB PF03099.14 EDN05609.1 - 1.1e-08 35.1 0.0 2.4e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Amidohydro_2 PF04909.9 EDN05610.1 - 3.5e-19 69.4 0.0 4.3e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.13 EDN05611.1 - 9e-29 100.1 1.1 1.8e-28 99.1 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN05611.1 - 8.5e-11 41.5 7.6 1.6e-10 40.7 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_2b PF00587.20 EDN05613.1 - 4.9e-50 169.4 0.0 6.8e-50 169.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDN05613.1 - 2.2e-07 30.7 0.0 6e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain Fungal_trans PF04082.13 EDN05614.1 - 2.4e-08 33.1 0.7 9.6e-08 31.2 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain ECH PF00378.15 EDN05615.1 - 7.7e-33 113.6 0.0 1.4e-32 112.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pyr_redox_2 PF07992.9 EDN05616.1 - 1.3e-36 126.4 0.3 2.1e-36 125.6 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EDN05616.1 - 9.1e-33 112.5 0.7 1.9e-32 111.5 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EDN05616.1 - 4.2e-15 55.9 0.2 4.2e-15 55.9 0.1 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDN05616.1 - 0.00062 19.8 0.0 0.0015 18.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDN05616.1 - 0.0032 16.4 0.0 0.0052 15.7 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 EDN05616.1 - 0.038 13.6 0.2 0.038 13.6 0.2 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EDN05616.1 - 0.059 12.4 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EDN05616.1 - 0.1 11.0 1.3 2.3 6.5 0.1 2.6 2 1 1 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.19 EDN05616.1 - 0.12 11.2 3.9 5.4 5.7 0.6 3.0 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.17 EDN05616.1 - 0.3 9.9 2.1 0.79 8.5 0.3 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A DAO PF01266.19 EDN05616.1 - 0.98 8.2 4.2 0.26 10.1 0.2 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pkinase PF00069.20 EDN05617.1 - 4.2e-49 167.0 0.0 1.5e-46 158.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05617.1 - 6e-32 110.7 0.0 5.5e-31 107.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN05617.1 - 0.00026 20.0 0.0 0.0004 19.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EDN05617.1 - 0.0015 17.4 0.1 0.0024 16.7 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EDN05617.1 - 0.087 11.6 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MFS_1 PF07690.11 EDN05619.1 - 3.4e-17 62.1 60.3 2.4e-16 59.3 40.1 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily EphA2_TM PF14575.1 EDN05619.1 - 0.43 11.0 2.9 68 3.9 0.1 3.9 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF3391 PF11871.3 EDN05620.1 - 0.034 14.3 0.1 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Bromodomain PF00439.20 EDN05621.1 - 4.2e-24 84.2 0.1 8.1e-24 83.3 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EDN05621.1 - 1.1e-08 35.1 0.3 2.5e-08 33.9 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN05621.1 - 1.2e-08 34.9 0.2 4.9e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Mem_trans PF03547.13 EDN05622.1 - 7.4e-50 169.3 3.1 1.2e-49 168.6 2.2 1.3 1 0 0 1 1 1 1 Membrane transport protein DUF2587 PF10759.4 EDN05623.1 - 0.017 14.5 0.1 0.017 14.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2587) Choline_kinase PF01633.15 EDN05624.1 - 2.9e-61 206.7 0.0 4.6e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EDN05624.1 - 4.8e-20 70.7 0.0 9e-20 69.8 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EDN05624.1 - 4.2e-10 39.7 0.7 1.4e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Peptidase_C12 PF01088.16 EDN05625.1 - 5.6e-69 231.5 0.0 8.7e-69 230.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DDE_1 PF03184.14 EDN05626.1 - 7.4e-37 126.5 0.0 1.4e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN05626.1 - 3.9e-11 42.5 0.8 8.7e-10 38.2 0.0 3.1 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain PFL PF02901.10 EDN05626.1 - 0.0078 14.6 0.7 0.013 13.9 0.5 1.3 1 0 0 1 1 1 1 Pyruvate formate lyase Zn_clus PF00172.13 EDN05627.1 - 1.8e-07 30.9 16.5 3.8e-07 29.9 11.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT PF02985.17 EDN05628.1 - 2.6e-29 98.6 14.3 2.4e-05 24.0 0.0 10.6 12 0 0 12 12 11 6 HEAT repeat HEAT_2 PF13646.1 EDN05628.1 - 3.3e-27 94.5 0.3 2.5e-09 37.3 0.0 8.1 4 3 4 8 8 8 7 HEAT repeats HEAT_EZ PF13513.1 EDN05628.1 - 8.3e-27 92.9 13.6 1.2e-13 51.0 0.0 11.6 9 3 5 14 14 13 4 HEAT-like repeat Cnd1 PF12717.2 EDN05628.1 - 6e-13 49.0 0.0 4.4e-06 26.6 0.0 4.4 4 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EDN05628.1 - 2.6e-11 43.7 0.0 0.021 15.2 0.0 6.6 4 3 3 8 8 8 3 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EDN05628.1 - 7.8e-11 41.3 1.1 0.025 13.3 0.0 5.1 5 0 0 5 5 5 3 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 EDN05628.1 - 4.2e-08 31.9 1.6 0.0055 15.0 0.3 4.5 2 2 1 3 3 3 3 Adaptin N terminal region Xpo1 PF08389.7 EDN05628.1 - 7.6e-07 29.1 0.0 0.00064 19.6 0.0 4.2 3 1 0 3 3 3 1 Exportin 1-like protein CLASP_N PF12348.3 EDN05628.1 - 7.5e-06 25.4 0.2 3.1 7.0 0.0 6.1 5 3 1 6 6 6 1 CLASP N terminal Arm PF00514.18 EDN05628.1 - 8.4e-06 25.4 2.9 0.31 10.9 0.0 6.1 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 EDN05628.1 - 0.00034 20.3 1.3 4.5 6.9 0.0 5.2 5 2 2 7 7 7 1 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.11 EDN05628.1 - 0.00075 19.7 0.3 0.52 10.9 0.0 4.2 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat DUF3437 PF11919.3 EDN05628.1 - 0.034 13.8 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF3437) Nipped-B_C PF12830.2 EDN05628.1 - 0.036 13.7 0.0 10 5.7 0.0 3.8 3 1 0 4 4 4 0 Sister chromatid cohesion C-terminus Syja_N PF02383.13 EDN05630.1 - 4.4e-97 324.6 0.0 6.4e-97 324.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Mg_trans_NIPA PF05653.9 EDN05631.1 - 4.4e-101 337.7 19.6 1.9e-52 178.1 0.7 2.0 1 1 1 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EDN05631.1 - 1.1e-05 25.5 3.6 1.1e-05 25.5 2.5 3.6 2 1 1 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 EDN05631.1 - 2.5e-05 24.2 6.1 2.5e-05 24.2 4.2 3.6 3 1 1 4 4 4 2 EamA-like transporter family LAB_N PF07578.6 EDN05631.1 - 0.034 14.0 0.4 0.28 11.1 0.2 2.3 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain DUF2937 PF11157.3 EDN05631.1 - 1 8.6 4.7 0.41 9.9 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF2157 PF09925.4 EDN05631.1 - 4.7 6.8 10.3 0.11 12.1 1.7 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Chromo PF00385.19 EDN05633.1 - 8.7e-06 25.3 0.5 1.7e-05 24.4 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain WD40 PF00400.27 EDN05634.1 - 5.4e-22 76.8 0.0 5.2e-14 51.5 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat NACHT PF05729.7 EDN05634.1 - 6.4e-10 38.9 0.2 2.7e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EDN05634.1 - 1.8e-06 28.0 0.0 7e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 EDN05634.1 - 0.00064 19.4 0.1 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 EDN05634.1 - 0.0014 18.7 0.0 0.0091 16.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EDN05634.1 - 0.0022 16.8 0.0 0.0059 15.4 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 EDN05634.1 - 0.015 15.4 0.2 0.062 13.4 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytochrom_D1 PF02239.11 EDN05634.1 - 0.016 13.5 0.0 0.029 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain AAA_18 PF13238.1 EDN05634.1 - 0.024 14.9 0.1 0.19 12.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EDN05634.1 - 0.028 14.0 0.1 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EDN05634.1 - 0.031 15.1 0.0 0.13 13.1 0.0 2.2 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EDN05634.1 - 0.035 13.7 0.0 0.091 12.4 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 EDN05634.1 - 0.043 13.6 0.1 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EDN05634.1 - 0.049 13.8 0.1 0.33 11.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 EDN05634.1 - 0.074 12.7 0.0 0.26 10.9 0.0 1.9 2 0 0 2 2 1 0 NTPase MobB PF03205.9 EDN05634.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EDN05634.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Spc97_Spc98 PF04130.8 EDN05635.1 - 0.036 12.3 0.0 0.041 12.1 0.0 1.0 1 0 0 1 1 1 0 Spc97 / Spc98 family DUF2130 PF09903.4 EDN05635.1 - 0.095 11.4 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) DASH_Dam1 PF08653.5 EDN05635.1 - 0.13 12.0 0.6 14 5.5 0.0 2.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 TPR_10 PF13374.1 EDN05636.1 - 1.4e-68 225.0 2.4 3e-12 46.0 0.0 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 EDN05636.1 - 5e-65 215.4 1.1 4.7e-16 58.4 0.0 4.7 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 EDN05636.1 - 1.5e-17 61.8 5.3 0.0051 16.5 0.0 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 EDN05636.1 - 9.5e-15 54.2 0.3 3.1e-14 52.5 0.2 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_1 PF00515.23 EDN05636.1 - 3.6e-11 42.1 3.8 0.76 9.4 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 EDN05636.1 - 4.9e-10 38.9 0.4 0.0034 17.0 0.0 3.9 2 1 2 4 4 4 3 TPR repeat NB-ARC PF00931.17 EDN05636.1 - 5.2e-10 38.6 0.7 1.3e-09 37.3 0.1 1.9 2 0 0 2 2 2 1 NB-ARC domain TPR_2 PF07719.12 EDN05636.1 - 8.6e-09 34.6 6.0 2.5 8.2 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDN05636.1 - 3.6e-08 32.9 2.6 0.78 10.0 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 EDN05636.1 - 1.3e-07 31.3 0.1 2.2 8.9 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDN05636.1 - 3.4e-07 30.5 1.8 0.68 10.3 0.1 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDN05636.1 - 2.6e-05 24.7 0.3 5.2 7.8 0.0 5.1 1 1 4 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN05636.1 - 3.5e-05 24.0 6.6 14 6.6 0.0 6.5 5 1 1 6 6 6 0 Tetratricopeptide repeat AAA_22 PF13401.1 EDN05636.1 - 4.3e-05 23.6 0.0 0.00013 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_8 PF13181.1 EDN05636.1 - 0.00042 19.8 5.8 2.7 7.9 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat AAA_14 PF13173.1 EDN05636.1 - 0.0032 17.3 0.0 0.0074 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN05636.1 - 0.0068 17.2 0.1 0.58 10.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain DUF4074 PF13293.1 EDN05636.1 - 0.033 14.4 0.0 53 4.1 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4074) Rapsyn_N PF10579.4 EDN05636.1 - 0.047 13.4 0.2 7.4 6.4 0.0 3.2 2 1 2 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TPR_3 PF07720.7 EDN05636.1 - 0.067 13.0 0.0 25 4.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CSTF_C PF14304.1 EDN05636.1 - 0.072 12.3 0.9 0.26 10.6 0.7 2.0 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal SRP54 PF00448.17 EDN05636.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Pkinase PF00069.20 EDN05637.1 - 2.2e-09 36.8 0.0 4.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN05637.1 - 0.0086 15.8 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN05637.1 - 0.011 14.7 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.17 EDN05637.1 - 0.1 11.9 0.0 0.47 9.7 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Zn_clus PF00172.13 EDN05639.1 - 1.6e-07 31.0 8.5 1.6e-07 31.0 5.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GvpG PF05120.7 EDN05640.1 - 0.034 13.9 1.8 0.091 12.5 1.2 1.7 1 0 0 1 1 1 0 Gas vesicle protein G Acetyltransf_11 PF13720.1 EDN05640.1 - 0.044 13.9 0.3 19 5.5 0.0 2.8 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 CorA PF01544.13 EDN05640.1 - 0.29 10.1 2.4 1 8.3 0.4 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein NAP PF00956.13 EDN05640.1 - 0.31 10.1 3.2 0.77 8.8 2.2 1.6 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) HSCB_C PF07743.8 EDN05640.1 - 2.2 8.8 10.9 6.4 7.3 0.5 3.6 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain CP2 PF04516.10 EDN05641.1 - 2.6e-88 295.0 0.0 4.7e-85 284.4 0.0 2.2 2 0 0 2 2 2 2 CP2 transcription factor bZIP_1 PF00170.16 EDN05641.1 - 0.013 15.4 5.8 0.014 15.3 1.6 2.2 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 EDN05641.1 - 0.038 13.8 6.2 0.17 11.7 0.6 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Acetyltransf_1 PF00583.19 EDN05642.1 - 0.062 13.3 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EDN05642.1 - 0.089 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ets PF00178.17 EDN05642.1 - 0.24 11.5 0.3 0.24 11.5 0.2 1.6 2 0 0 2 2 2 0 Ets-domain zf-RING_5 PF14634.1 EDN05644.1 - 3.6e-08 32.9 5.6 5.9e-08 32.3 3.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDN05644.1 - 2.3e-07 30.3 5.8 4e-07 29.5 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN05644.1 - 2.5e-07 30.2 9.4 3.8e-07 29.6 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN05644.1 - 1.2e-05 25.2 8.3 2.2e-05 24.3 5.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN05644.1 - 2.3e-05 24.1 11.9 3.9e-05 23.3 8.3 1.4 1 0 0 1 1 1 1 Ring finger domain Lebercilin PF15619.1 EDN05644.1 - 0.0012 18.3 4.3 0.0018 17.7 3.0 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease zf-RING_6 PF14835.1 EDN05644.1 - 0.0014 18.3 5.8 0.0023 17.6 4.1 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein HAP1_N PF04849.8 EDN05644.1 - 0.0031 16.5 1.6 0.0041 16.1 1.1 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF4618 PF15397.1 EDN05644.1 - 0.0031 16.8 1.0 0.0044 16.3 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) zf-RING_4 PF14570.1 EDN05644.1 - 0.019 14.5 3.2 0.019 14.5 2.2 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain IncA PF04156.9 EDN05644.1 - 0.021 14.4 4.5 0.03 13.9 3.1 1.2 1 0 0 1 1 1 0 IncA protein AAA_23 PF13476.1 EDN05644.1 - 0.023 15.0 0.4 0.027 14.7 0.3 1.1 1 0 0 1 1 1 0 AAA domain HAUS6_N PF14661.1 EDN05644.1 - 0.033 13.5 1.7 0.049 12.9 1.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Prominin PF05478.6 EDN05644.1 - 0.039 11.4 0.3 0.048 11.1 0.2 1.1 1 0 0 1 1 1 0 Prominin Cauli_DNA-bind PF03310.8 EDN05644.1 - 0.047 13.5 0.5 0.29 10.9 0.0 2.4 2 1 1 3 3 3 0 Caulimovirus DNA-binding protein DNA_pol3_delta PF06144.8 EDN05644.1 - 0.048 13.1 0.6 0.07 12.6 0.4 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Med28 PF11594.3 EDN05644.1 - 0.093 12.9 2.8 0.12 12.5 0.8 1.8 1 1 1 2 2 2 0 Mediator complex subunit 28 RmuC PF02646.11 EDN05644.1 - 0.22 10.3 3.1 0.3 9.8 2.1 1.1 1 0 0 1 1 1 0 RmuC family FlaC_arch PF05377.6 EDN05644.1 - 0.25 11.2 2.1 14 5.6 0.2 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Macoilin PF09726.4 EDN05644.1 - 0.27 9.4 4.2 0.38 8.9 2.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Tnp_P_element PF12017.3 EDN05644.1 - 0.35 10.0 1.9 0.82 8.8 1.2 1.7 2 0 0 2 2 2 0 Transposase protein DUF1272 PF06906.6 EDN05644.1 - 0.44 10.4 6.2 0.84 9.5 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Fib_alpha PF08702.5 EDN05644.1 - 0.48 10.5 4.3 1 9.4 2.4 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 EDN05644.1 - 0.54 10.0 2.1 1.4 8.7 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.16 EDN05644.1 - 0.54 10.2 6.3 0.42 10.6 2.4 2.1 2 0 0 2 2 2 0 bZIP transcription factor DMPK_coil PF08826.5 EDN05644.1 - 0.9 9.4 6.8 1.9 8.4 4.7 1.5 1 0 0 1 1 1 0 DMPK coiled coil domain like zf-RING_UBOX PF13445.1 EDN05644.1 - 1 9.1 7.0 2 8.2 3.8 2.3 1 1 1 2 2 2 0 RING-type zinc-finger NUDE_C PF04880.8 EDN05644.1 - 2 8.7 7.0 0.55 10.5 2.7 1.6 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region zf-C3HC4_4 PF15227.1 EDN05644.1 - 3.5 7.5 10.4 5.1 7.0 6.2 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EDN05644.1 - 4.2 6.9 8.1 11 5.5 5.6 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DegS PF05384.6 EDN05645.1 - 8.9e-05 21.7 1.9 0.00013 21.2 1.3 1.2 1 0 0 1 1 1 1 Sensor protein DegS zf-C3HC4 PF00097.20 EDN05645.1 - 0.00047 19.7 8.2 0.00088 18.8 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN05645.1 - 0.001 18.6 9.6 0.0015 18.1 6.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NTR2 PF15458.1 EDN05645.1 - 0.0016 17.7 1.6 0.0019 17.5 1.1 1.1 1 0 0 1 1 1 1 Nineteen complex-related protein 2 zf-RING_5 PF14634.1 EDN05645.1 - 0.0038 16.9 8.0 0.0062 16.2 5.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Macoilin PF09726.4 EDN05645.1 - 0.0043 15.4 3.3 0.0054 15.0 2.3 1.1 1 0 0 1 1 1 1 Transmembrane protein TMF_TATA_bd PF12325.3 EDN05645.1 - 0.0053 16.4 1.4 0.0078 15.9 1.0 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF2730 PF10805.3 EDN05645.1 - 0.0064 16.2 0.5 0.0099 15.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) DivIC PF04977.10 EDN05645.1 - 0.0075 15.7 1.2 0.013 14.9 0.8 1.4 1 0 0 1 1 1 1 Septum formation initiator Med28 PF11594.3 EDN05645.1 - 0.012 15.7 0.7 0.019 15.1 0.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 28 Troponin PF00992.15 EDN05645.1 - 0.013 15.5 5.2 0.024 14.7 3.6 1.3 1 0 0 1 1 1 0 Troponin ADIP PF11559.3 EDN05645.1 - 0.019 14.8 1.9 0.032 14.1 1.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 EDN05645.1 - 0.025 14.5 5.4 0.042 13.7 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Fez1 PF06818.10 EDN05645.1 - 0.029 14.3 1.9 0.032 14.2 0.9 1.4 2 0 0 2 2 1 0 Fez1 HALZ PF02183.13 EDN05645.1 - 0.032 13.9 1.2 0.051 13.2 0.6 1.5 1 1 0 1 1 1 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 EDN05645.1 - 0.049 13.5 2.1 8.7 6.3 1.5 2.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) RmuC PF02646.11 EDN05645.1 - 0.05 12.4 1.0 0.071 11.9 0.7 1.1 1 0 0 1 1 1 0 RmuC family TMF_DNA_bd PF12329.3 EDN05645.1 - 0.051 13.3 1.3 0.093 12.5 0.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spectrin PF00435.16 EDN05645.1 - 0.053 13.8 0.8 0.076 13.3 0.6 1.2 1 0 0 1 1 1 0 Spectrin repeat DUF641 PF04859.7 EDN05645.1 - 0.053 13.2 1.0 0.086 12.5 0.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.5 EDN05645.1 - 0.059 13.4 0.7 0.092 12.8 0.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HAUS5 PF14817.1 EDN05645.1 - 0.065 11.7 2.9 0.086 11.3 2.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF1192 PF06698.6 EDN05645.1 - 0.067 13.0 2.5 0.14 12.0 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4618 PF15397.1 EDN05645.1 - 0.068 12.4 1.5 0.091 12.0 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Tropomyosin_1 PF12718.2 EDN05645.1 - 0.075 12.8 4.9 0.12 12.2 3.4 1.2 1 0 0 1 1 1 0 Tropomyosin like zf-C3HC4_2 PF13923.1 EDN05645.1 - 0.092 12.7 9.2 0.17 11.9 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4164 PF13747.1 EDN05645.1 - 0.15 12.2 5.0 0.26 11.4 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF3373 PF11853.3 EDN05645.1 - 0.17 10.3 0.2 0.21 10.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Apelin PF15360.1 EDN05645.1 - 0.18 12.0 0.2 0.18 12.0 0.2 2.1 2 1 0 2 2 2 0 APJ endogenous ligand Prefoldin_2 PF01920.15 EDN05645.1 - 0.21 11.3 4.1 0.41 10.4 2.9 1.5 1 1 0 1 1 1 0 Prefoldin subunit IncA PF04156.9 EDN05645.1 - 0.46 10.0 3.1 0.67 9.5 2.2 1.2 1 0 0 1 1 1 0 IncA protein CENP-Q PF13094.1 EDN05645.1 - 0.5 10.3 6.2 1.2 9.1 4.2 1.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-RING_2 PF13639.1 EDN05645.1 - 0.7 9.7 12.6 1.5 8.7 8.7 1.6 1 0 0 1 1 1 0 Ring finger domain DUF3435 PF11917.3 EDN05646.1 - 1.5e-35 122.7 0.0 1e-34 119.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) DUF371 PF04027.8 EDN05646.1 - 0.1 12.2 0.0 9.4 5.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF371) CEP44 PF15007.1 EDN05647.1 - 0.056 13.1 0.2 0.063 12.9 0.2 1.1 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 Adap_comp_sub PF00928.16 EDN05648.1 - 5.4e-22 78.1 0.2 8.1e-22 77.5 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EDN05648.1 - 5.2e-08 32.7 0.2 9.2e-08 31.9 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 EDN05648.1 - 0.0077 16.3 0.2 0.016 15.3 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF3647 PF12363.3 EDN05648.1 - 0.035 14.2 0.6 0.067 13.3 0.4 1.5 1 0 0 1 1 1 0 Phage protein DUF2420 PF10336.4 EDN05649.1 - 7.3e-12 44.8 0.0 1.9e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) PRMT5 PF05185.11 EDN05650.1 - 0.073 11.9 0.0 0.079 11.8 0.0 1.1 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase OMPdecase PF00215.19 EDN05652.1 - 2e-07 30.6 0.0 5e-06 26.0 0.0 2.4 3 0 0 3 3 3 2 Orotidine 5'-phosphate decarboxylase / HUMPS family Cyt-b5 PF00173.23 EDN05653.1 - 1.3e-19 69.7 0.3 5e-18 64.6 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EDN05653.1 - 8.7e-09 35.7 18.6 2.6e-08 34.2 11.1 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RRM_1 PF00076.17 EDN05654.1 - 3.7e-40 135.3 0.4 8.8e-19 66.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN05654.1 - 8.3e-32 108.9 0.1 3e-17 62.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EDN05654.1 - 9.5e-31 105.9 0.1 2.2e-30 104.7 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EDN05654.1 - 1.3e-21 76.1 0.0 5.7e-09 35.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDN05654.1 - 0.04 13.7 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif MIP-T3 PF10243.4 EDN05654.1 - 6.1 5.1 26.5 22 3.3 18.7 1.6 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Myosin_tail_1 PF01576.14 EDN05655.1 - 0.003 15.3 0.6 0.0039 14.9 0.4 1.0 1 0 0 1 1 1 1 Myosin tail MAD PF05557.8 EDN05655.1 - 0.0073 14.4 1.4 0.0097 14.0 1.0 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Tropomyosin PF00261.15 EDN05655.1 - 0.011 14.8 3.7 0.015 14.3 2.6 1.1 1 0 0 1 1 1 0 Tropomyosin Spc7 PF08317.6 EDN05655.1 - 0.011 14.3 2.3 0.018 13.7 1.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein SPATA24 PF15175.1 EDN05655.1 - 0.02 14.5 0.6 0.032 13.9 0.4 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF3584 PF12128.3 EDN05655.1 - 0.039 11.3 3.0 0.05 10.9 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Med2 PF11214.3 EDN05655.1 - 0.052 13.5 0.6 0.13 12.3 0.2 1.7 1 1 1 2 2 2 0 Mediator complex subunit 2 CENP-Q PF13094.1 EDN05655.1 - 0.11 12.4 2.6 0.25 11.3 1.8 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4200 PF13863.1 EDN05655.1 - 0.14 12.1 3.3 0.22 11.4 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Syntaxin PF00804.20 EDN05655.1 - 0.22 11.6 4.7 0.51 10.5 3.3 1.6 1 0 0 1 1 1 0 Syntaxin IncA PF04156.9 EDN05655.1 - 0.38 10.3 4.0 0.55 9.8 2.8 1.2 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 EDN05655.1 - 0.73 8.7 4.6 1.1 8.1 3.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 EDN05655.1 - 0.86 9.4 6.7 2.2 8.1 4.8 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3552 PF12072.3 EDN05655.1 - 0.94 8.6 7.4 0.29 10.3 2.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) SlyX PF04102.7 EDN05655.1 - 1.5 9.2 3.9 3.1 8.2 0.2 2.6 1 1 1 2 2 2 0 SlyX PP2C PF00481.16 EDN05656.1 - 3.3e-33 115.1 0.0 1.9e-27 96.2 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EDN05656.1 - 0.00021 20.7 0.1 0.00058 19.3 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C Iso_dh PF00180.15 EDN05657.1 - 8.7e-129 429.4 0.0 9.9e-129 429.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase APC10 PF03256.11 EDN05658.1 - 5.3e-30 104.4 0.0 1.2e-21 77.1 0.0 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) CENP-B_dimeris PF09026.5 EDN05658.1 - 0.024 14.8 7.4 0.024 14.8 5.1 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CDP-OH_P_transf PF01066.16 EDN05659.1 - 9.6e-19 67.5 4.7 9.6e-19 67.5 3.2 1.7 1 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase E1-E2_ATPase PF00122.15 EDN05661.1 - 2.8e-63 213.0 2.8 4.7e-63 212.3 1.9 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDN05661.1 - 1.6e-33 115.7 10.4 1.6e-33 115.7 7.2 2.6 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDN05661.1 - 1.6e-29 103.8 0.0 1.3e-27 97.5 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN05661.1 - 3.2e-17 62.2 0.0 6.4e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EDN05661.1 - 3.9e-13 49.9 0.0 9.6e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDN05661.1 - 3e-09 36.1 0.0 8.2e-09 34.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EDN05661.1 - 0.00014 21.5 0.2 0.00074 19.1 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EDN05662.1 - 2.3e-17 62.9 0.0 2.8e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05662.1 - 6.7e-05 22.0 0.0 7.4e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN05662.1 - 0.0014 18.4 0.1 0.016 14.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EDN05662.1 - 0.0047 15.9 0.0 0.0057 15.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDN05662.1 - 0.027 13.5 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EDN05662.1 - 0.03 13.6 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.15 EDN05662.1 - 0.042 12.9 0.0 0.091 11.8 0.0 1.5 2 0 0 2 2 2 0 Ecdysteroid kinase PS_Dcarbxylase PF02666.10 EDN05663.1 - 9.5e-78 260.1 0.0 3.4e-77 258.3 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase ubiquitin PF00240.18 EDN05664.1 - 0.0019 17.5 0.0 0.0038 16.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Terpene_synth_C PF03936.11 EDN05665.1 - 2.8e-08 33.3 0.3 2.6e-05 23.6 0.2 2.2 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Tobravirus_2B PF05271.6 EDN05665.1 - 0.054 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Tobravirus 2B protein MATH PF00917.21 EDN05667.1 - 0.13 12.5 0.1 0.28 11.4 0.0 1.6 2 0 0 2 2 2 0 MATH domain His_Phos_1 PF00300.17 EDN05668.1 - 1.2e-14 54.6 0.0 1.9e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_S8 PF00410.14 EDN05669.1 - 4.6e-25 87.9 0.1 6.5e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ank_2 PF12796.2 EDN05670.1 - 2.5e-52 175.1 5.2 3.1e-12 46.6 0.0 5.7 3 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EDN05670.1 - 2.7e-51 168.9 11.1 1.5e-08 34.0 0.0 11.0 10 2 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 EDN05670.1 - 3e-38 128.9 10.4 3.1e-10 39.9 0.1 6.9 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN05670.1 - 5.6e-37 125.4 5.5 2e-06 28.1 0.1 8.3 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN05670.1 - 2.1e-32 107.8 10.9 1.2e-05 25.0 0.0 11.1 10 3 0 10 10 10 6 Ankyrin repeat F-box-like PF12937.2 EDN05670.1 - 0.0038 16.9 0.0 0.0089 15.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like PmrD PF11183.3 EDN05670.1 - 0.1 12.3 0.0 0.76 9.6 0.0 2.5 1 1 1 2 2 2 0 Polymyxin resistance protein PmrD HEAT PF02985.17 EDN05671.1 - 1.2e-16 59.2 10.2 0.00037 20.3 0.0 9.7 10 0 0 10 10 10 3 HEAT repeat HEAT_2 PF13646.1 EDN05671.1 - 3e-13 49.8 10.9 1.3e-05 25.3 0.0 6.5 2 2 6 8 8 8 6 HEAT repeats HEAT_EZ PF13513.1 EDN05671.1 - 2.6e-09 37.2 15.9 1.3e-06 28.7 0.0 8.0 9 3 2 11 11 11 2 HEAT-like repeat IBN_N PF03810.14 EDN05671.1 - 1e-08 34.9 1.2 1.8e-06 27.7 0.1 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.18 EDN05671.1 - 9.2e-06 25.2 3.2 2.4 8.1 0.0 5.6 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EDN05671.1 - 1.9e-05 24.1 2.3 0.11 11.8 0.0 4.6 3 2 2 5 5 5 2 CLASP N terminal HEAT_PBS PF03130.11 EDN05671.1 - 0.00024 21.2 0.1 2.6 8.7 0.0 5.1 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat DUF3535 PF12054.3 EDN05671.1 - 0.00094 17.9 0.9 0.0039 15.8 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) Proteasom_PSMB PF10508.4 EDN05671.1 - 0.0066 14.7 0.2 3 5.9 0.0 3.1 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit Apc4 PF12896.2 EDN05672.1 - 1e-66 224.2 0.3 1.5e-66 223.7 0.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EDN05672.1 - 5e-15 54.7 0.0 1.2e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain IL1 PF00340.14 EDN05672.1 - 0.13 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Interleukin-1 / 18 Pkinase PF00069.20 EDN05674.1 - 2e-09 36.9 0.0 3.5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN05674.1 - 0.0091 15.7 0.0 0.024 14.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN05674.1 - 0.024 13.7 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DCD PF06559.6 EDN05678.1 - 0.11 10.8 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) APH PF01636.18 EDN05680.1 - 2.8e-16 60.0 0.1 4e-16 59.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN05680.1 - 8e-05 22.3 0.0 0.00017 21.2 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase DEAD PF00270.24 EDN05681.1 - 3e-11 43.1 0.0 6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN05681.1 - 5.4e-05 23.1 0.1 0.00076 19.3 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDN05681.1 - 0.11 12.6 0.1 0.39 10.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.20 EDN05682.1 - 4.5e-09 35.8 0.1 7.9e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN05682.1 - 0.013 15.2 0.0 0.039 13.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN05682.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DDE_1 PF03184.14 EDN05684.1 - 1.5e-26 92.8 0.0 2.6e-25 88.8 0.0 2.6 2 1 0 2 2 2 1 DDE superfamily endonuclease DUF1675 PF07897.6 EDN05684.1 - 5.4 6.7 12.6 9.7 5.9 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF3435 PF11917.3 EDN05685.1 - 7.4e-12 44.7 0.0 7.4e-12 44.7 0.0 2.7 4 0 0 4 4 4 1 Protein of unknown function (DUF3435) DUF668 PF05003.7 EDN05685.1 - 0.061 13.5 0.0 8.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF668) VWA_2 PF13519.1 EDN05686.1 - 1.1e-05 25.6 0.0 3.2e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EDN05686.1 - 1.3e-05 25.0 0.0 7.3e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EDN05686.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain Acetyltransf_1 PF00583.19 EDN05688.1 - 2.6e-08 33.7 0.0 4.7e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN05688.1 - 3.6e-07 30.2 0.0 6.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDN05688.1 - 4.3e-07 30.0 0.0 1.3e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EDN05688.1 - 0.00022 21.0 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EDN05688.1 - 0.051 13.4 0.0 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain BTB PF00651.26 EDN05689.1 - 5.3e-06 26.3 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain CDC45 PF02724.9 EDN05690.1 - 4.5e-204 679.0 14.7 7.3e-182 605.6 0.0 3.0 1 1 2 3 3 3 2 CDC45-like protein SDA1 PF05285.7 EDN05690.1 - 0.004 16.4 15.2 0.004 16.4 10.6 2.2 2 0 0 2 2 2 1 SDA1 Nop25 PF09805.4 EDN05690.1 - 0.29 11.2 22.1 0.14 12.2 9.7 2.4 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Herpes_DNAp_acc PF04929.7 EDN05690.1 - 3 6.7 9.6 0.086 11.7 0.2 2.3 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Nop14 PF04147.7 EDN05690.1 - 4.3 5.1 25.5 0.12 10.2 9.0 2.1 2 0 0 2 2 2 0 Nop14-like family FAM60A PF15396.1 EDN05690.1 - 6.3 6.4 13.5 0.17 11.6 2.3 2.2 2 0 0 2 2 2 0 Protein Family FAM60A BUD22 PF09073.5 EDN05690.1 - 6.9 5.6 36.3 5.5 5.9 13.3 2.3 2 0 0 2 2 2 0 BUD22 Peptidase_C13 PF01650.13 EDN05691.1 - 3e-40 138.1 0.0 3.7e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family F-box-like PF12937.2 EDN05692.1 - 5.8e-11 41.9 0.1 1.5e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN05692.1 - 1.2e-06 27.9 0.1 3.6e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 F-box domain DUF1014 PF06244.7 EDN05693.1 - 2.9e-24 85.6 7.5 7.9e-24 84.2 5.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Toprim_4 PF13662.1 EDN05693.1 - 1.7 8.6 4.2 0.3 11.1 0.1 2.0 2 1 0 2 2 2 0 Toprim domain Alpha-amylase PF00128.19 EDN05694.1 - 4.7e-13 49.2 0.7 8.9e-13 48.3 0.5 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EDN05694.1 - 2.4e-05 22.3 0.0 0.018 12.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 70 Mito_carr PF00153.22 EDN05695.1 - 9.5e-47 156.6 7.1 1.4e-17 63.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Flavin_Reduct PF01613.13 EDN05698.1 - 1.8e-18 66.8 0.0 3.5e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Flavin reductase like domain PAP_central PF04928.12 EDN05699.1 - 5.2e-104 346.5 0.0 6.8e-104 346.1 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EDN05699.1 - 7e-47 158.8 0.0 1.2e-46 158.0 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EDN05699.1 - 3.1e-10 40.2 0.1 6.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap PF03813.9 EDN05699.1 - 0.087 10.3 0.0 0.13 9.8 0.0 1.1 1 0 0 1 1 1 0 Nrap protein Amidase PF01425.16 EDN05700.1 - 5.8e-86 289.0 0.0 6.9e-86 288.8 0.0 1.0 1 0 0 1 1 1 1 Amidase Pyr_redox_2 PF07992.9 EDN05701.1 - 2.2e-27 96.2 0.0 4.1e-27 95.3 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN05701.1 - 1.4e-08 34.9 0.0 2.4e-07 31.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDN05701.1 - 0.0049 16.9 0.0 0.039 14.0 0.0 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN05701.1 - 0.03 14.0 0.0 0.39 10.4 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF2321 PF10083.4 EDN05702.1 - 0.059 12.8 0.6 0.1 12.1 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) FAM60A PF15396.1 EDN05702.1 - 0.76 9.4 5.8 1.1 8.9 4.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Trypan_glycop PF00913.14 EDN05702.1 - 1.1 8.1 5.8 0.23 10.3 1.1 1.8 1 1 1 2 2 2 0 Trypanosome variant surface glycoprotein (A-type) HSP20 PF00011.16 EDN05703.1 - 4.2e-10 39.3 0.1 8.4e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Herpes_capsid PF06112.6 EDN05703.1 - 0.84 9.6 4.9 1.5 8.8 0.8 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Pectate_lyase_3 PF12708.2 EDN05706.1 - 4.3e-92 308.3 15.5 1.8e-71 240.8 8.7 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EDN05706.1 - 3.4e-08 32.8 2.4 0.00034 20.0 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Aminotran_1_2 PF00155.16 EDN05707.1 - 1.3e-19 70.3 0.0 2.9e-16 59.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II PAP_central PF04928.12 EDN05711.1 - 9.6e-22 77.0 0.0 1.5e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain 2_5_RNA_ligase2 PF13563.1 EDN05711.1 - 5.1e-16 58.7 0.0 1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily DUF504 PF04457.7 EDN05711.1 - 3.6e-14 52.6 0.2 8.7e-14 51.4 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF504) Exo_endo_phos PF03372.18 EDN05711.1 - 1.4e-09 38.2 0.0 3.1e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PAP_RNA-bind PF04926.10 EDN05711.1 - 0.00059 19.3 0.1 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EDN05711.1 - 0.00089 19.5 0.0 0.0026 18.0 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain TarH PF02203.10 EDN05711.1 - 0.025 14.4 0.3 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Tar ligand binding domain homologue Exo_endo_phos_2 PF14529.1 EDN05711.1 - 0.029 13.9 0.0 1.7 8.2 0.0 3.1 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase Cation_efflux PF01545.16 EDN05712.1 - 6.4e-26 91.0 5.4 7.8e-26 90.7 3.7 1.1 1 0 0 1 1 1 1 Cation efflux family ADH_zinc_N_2 PF13602.1 EDN05714.1 - 4.4e-22 79.3 0.0 4.7e-21 76.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EDN05714.1 - 5e-15 55.2 0.7 2.5e-14 52.9 0.2 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase GAT PF03127.9 EDN05715.1 - 5.4e-09 35.9 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 GAT domain PROCN PF08083.6 EDN05715.1 - 0.21 9.9 0.1 0.3 9.4 0.1 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain NAD_binding_6 PF08030.7 EDN05717.1 - 7.8e-14 51.8 0.1 6.2e-10 39.1 0.0 2.6 2 1 1 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EDN05717.1 - 6.8e-12 45.1 0.2 4.3e-06 26.5 0.1 2.4 1 1 0 2 2 2 2 FAD-binding domain Ferric_reduct PF01794.14 EDN05717.1 - 1.1e-10 41.6 5.5 1.1e-10 41.6 3.8 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EDN05717.1 - 0.0075 16.8 0.0 0.093 13.3 0.0 2.6 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain adh_short PF00106.20 EDN05718.1 - 4.3e-20 72.3 0.0 5.9e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN05718.1 - 1.3e-15 57.8 0.0 1.5e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN05718.1 - 0.00029 20.5 0.0 0.00045 19.9 0.0 1.4 1 1 0 1 1 1 1 KR domain Gag_spuma PF03276.9 EDN05718.1 - 0.14 10.4 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Fungal_trans PF04082.13 EDN05719.1 - 9.3e-14 50.9 0.0 2.3e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EDN05719.1 - 9.5e-10 38.6 0.0 2.4e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Zn_clus PF00172.13 EDN05719.1 - 9.8e-06 25.3 8.1 1.8e-05 24.5 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 EDN05719.1 - 0.0038 17.0 0.0 0.074 12.7 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.7 EDN05720.1 - 1.7e-26 92.1 0.1 9.9e-26 89.6 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN05720.1 - 1.9e-09 37.1 0.1 1.8e-08 33.9 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 EDN05720.1 - 0.034 13.1 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase ApbA PF02558.11 EDN05720.1 - 0.044 13.2 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EDN05720.1 - 0.13 12.0 0.1 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 ThiF family DDE_3 PF13358.1 EDN05722.1 - 3.7e-08 33.2 0.4 5.6e-08 32.6 0.3 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease 2-Hacid_dh_C PF02826.14 EDN05723.1 - 7.5e-54 181.5 0.0 1.1e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDN05723.1 - 9.5e-21 73.6 0.0 1.2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Ribosomal_L22 PF00237.14 EDN05724.1 - 3.1e-35 120.2 0.0 4.7e-35 119.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Glyco_hydro_20 PF00728.17 EDN05725.1 - 2.5e-32 112.4 0.7 2e-31 109.4 0.5 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 EDN05725.1 - 2e-10 41.2 0.0 5.2e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Epimerase PF01370.16 EDN05726.1 - 5.4e-11 42.3 0.0 1e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDN05726.1 - 4.7e-08 32.0 0.0 7e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EDN05726.1 - 8.1e-08 31.4 0.1 0.00091 18.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EDN05726.1 - 5.4e-06 26.5 0.1 2.3e-05 24.5 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EDN05726.1 - 0.007 15.6 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family UBA_4 PF14555.1 EDN05727.1 - 7e-12 44.6 0.1 1.7e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EDN05727.1 - 1e-09 38.2 0.0 2.5e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 UBX domain Asp-B-Hydro_N PF05279.6 EDN05727.1 - 0.0046 16.8 0.7 0.0081 16.0 0.5 1.3 1 0 0 1 1 1 1 Aspartyl beta-hydroxylase N-terminal region DUF1682 PF07946.9 EDN05727.1 - 0.01 14.6 0.7 0.014 14.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Paf1 PF03985.8 EDN05727.1 - 0.53 8.9 6.8 0.9 8.2 4.7 1.3 1 0 0 1 1 1 0 Paf1 PKK PF12474.3 EDN05727.1 - 0.61 9.8 13.9 1.1 8.9 9.6 1.4 1 0 0 1 1 1 0 Polo kinase kinase DDRGK PF09756.4 EDN05727.1 - 3.5 6.9 13.5 6 6.2 9.4 1.3 1 0 0 1 1 1 0 DDRGK domain Pkinase PF00069.20 EDN05728.1 - 2.4e-08 33.4 0.0 4.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05728.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase LSM PF01423.17 EDN05729.1 - 1.4e-17 62.9 0.2 2.1e-17 62.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain FimP PF09766.4 EDN05729.1 - 0.0055 15.8 0.4 0.006 15.7 0.3 1.0 1 0 0 1 1 1 1 Fms-interacting protein Med15 PF09606.5 EDN05729.1 - 0.019 13.2 17.0 0.018 13.2 11.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3371 PF11851.3 EDN05729.1 - 0.023 15.3 0.9 0.029 15.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) FAM60A PF15396.1 EDN05729.1 - 0.07 12.8 0.1 0.095 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4175 PF13779.1 EDN05729.1 - 0.084 10.5 16.0 0.089 10.4 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.9 EDN05729.1 - 0.14 11.8 1.2 0.16 11.6 0.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 EDN05729.1 - 0.4 10.0 3.3 0.53 9.6 2.3 1.1 1 0 0 1 1 1 0 Spt20 family dsDNA_bind PF01984.15 EDN05729.1 - 1.5 8.8 13.1 2.4 8.1 9.1 1.3 1 0 0 1 1 1 0 Double-stranded DNA-binding domain DUF2201_N PF13203.1 EDN05729.1 - 2.2 7.4 7.1 2.7 7.0 4.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF533 PF04391.7 EDN05729.1 - 6.3 6.1 10.1 8.8 5.6 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) AAA PF00004.24 EDN05730.1 - 2.1e-19 70.0 0.0 3.6e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EDN05730.1 - 4.7e-05 23.6 0.2 0.00064 20.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDN05730.1 - 0.00012 22.1 0.0 0.00036 20.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EDN05730.1 - 0.00015 21.5 0.0 0.00032 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EDN05730.1 - 0.00016 21.3 0.1 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EDN05730.1 - 0.00023 21.9 1.1 0.00098 19.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDN05730.1 - 0.0006 19.9 0.7 0.0077 16.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EDN05730.1 - 0.0032 16.8 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EDN05730.1 - 0.0038 17.1 0.1 0.034 14.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain Zot PF05707.7 EDN05730.1 - 0.0047 16.4 0.2 0.12 11.7 0.0 2.3 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) Mg_chelatase PF01078.16 EDN05730.1 - 0.0088 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EDN05730.1 - 0.023 14.6 0.2 0.092 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.9 EDN05730.1 - 0.025 14.5 0.0 0.11 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_30 PF13604.1 EDN05730.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EDN05730.1 - 0.079 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EDN05730.1 - 0.095 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EDN05730.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EDN05730.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EDN05730.1 - 0.11 11.5 0.4 0.24 10.5 0.1 1.6 2 0 0 2 2 2 0 KaiC AAA_11 PF13086.1 EDN05730.1 - 0.15 11.5 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.13 EDN05731.1 - 0.089 12.7 10.5 0.24 11.3 7.3 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM125 PF15109.1 EDN05732.1 - 0.21 11.7 0.5 0.42 10.7 0.1 1.6 2 0 0 2 2 2 0 TMEM125 protein family CASP_C PF08172.7 EDN05734.1 - 3.1e-87 291.7 3.9 3.1e-87 291.7 2.7 3.4 2 1 1 3 3 3 1 CASP C terminal TPR_MLP1_2 PF07926.7 EDN05734.1 - 5.5 6.7 58.9 0.066 12.9 2.2 5.9 3 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein DUF2990 PF11693.3 EDN05735.1 - 5.6e-05 22.9 0.6 0.0001 22.0 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2990) Mannosyl_trans3 PF11051.3 EDN05736.1 - 1.9e-69 234.0 0.0 7.6e-69 232.0 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative Fibrillarin PF01269.12 EDN05737.1 - 4e-76 254.9 0.0 5.2e-76 254.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EDN05737.1 - 0.00013 21.5 0.1 0.00024 20.6 0.1 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Nol1_Nop2_Fmu PF01189.12 EDN05737.1 - 0.081 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 NOL1/NOP2/sun family PCMT PF01135.14 EDN05737.1 - 0.087 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Epimerase PF01370.16 EDN05738.1 - 0.00047 19.6 0.0 0.00074 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDN05738.1 - 0.097 11.3 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Peptidase_M16 PF00675.15 EDN05739.1 - 6e-56 188.3 0.4 1.8e-55 186.7 0.3 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EDN05739.1 - 3.6e-38 131.0 0.0 8.7e-37 126.5 0.0 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain ADH_zinc_N PF00107.21 EDN05740.1 - 5.2e-21 74.5 0.0 8.3e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN05740.1 - 8e-09 36.4 0.0 1.3e-08 35.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CybS PF05328.7 EDN05741.1 - 3.2e-54 182.1 0.0 7.8e-54 180.8 0.0 1.6 2 0 0 2 2 2 1 CybS Maf PF02545.9 EDN05742.1 - 5.2e-44 149.7 0.0 6.3e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein HLH PF00010.21 EDN05743.1 - 1.3e-07 31.2 0.0 3.3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF605 PF04652.11 EDN05743.1 - 0.037 13.4 12.7 0.035 13.5 8.8 1.1 1 0 0 1 1 1 0 Vta1 like CytochromB561_N PF09786.4 EDN05743.1 - 1.1 7.6 10.2 1.2 7.5 7.0 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Presenilin PF01080.12 EDN05743.1 - 2.8 6.6 4.2 2.8 6.6 2.9 1.1 1 0 0 1 1 1 0 Presenilin DUF566 PF04484.7 EDN05743.1 - 3.7 6.9 14.9 4.4 6.7 10.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ndc1_Nup PF09531.5 EDN05743.1 - 6.6 5.0 9.1 7.4 4.8 6.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GFA PF04828.9 EDN05744.1 - 0.0025 17.7 0.0 0.0051 16.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EDN05744.1 - 1.1 8.5 4.6 0.17 11.1 0.3 1.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 EDN05744.1 - 9 5.9 8.7 0.46 10.0 1.3 2.3 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain UBA_4 PF14555.1 EDN05746.1 - 0.0089 15.5 0.1 0.062 12.8 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain rve_2 PF13333.1 EDN05748.1 - 0.078 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain DUF3328 PF11807.3 EDN05750.1 - 5.4e-40 137.3 0.1 7.1e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_47 PF01532.15 EDN05751.1 - 8.3e-134 446.6 0.0 9.5e-134 446.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GST_C PF00043.20 EDN05752.1 - 3.6e-15 55.7 0.0 8.6e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EDN05752.1 - 1.2e-11 44.5 0.0 4e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EDN05752.1 - 4.6e-11 42.7 0.0 1.1e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDN05752.1 - 2.6e-10 40.1 0.0 6.7e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDN05752.1 - 7.7e-10 38.5 0.1 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDN05752.1 - 1.6e-07 31.6 0.1 2.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Histidinol_dh PF00815.15 EDN05754.1 - 5.9e-179 594.9 6.1 9.3e-179 594.3 4.2 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EDN05754.1 - 8.7e-26 89.3 0.3 1.8e-25 88.3 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase adh_short PF00106.20 EDN05754.1 - 2.6e-17 63.2 2.1 3e-17 63.0 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase PRA-PH PF01503.12 EDN05754.1 - 2.8e-11 43.5 1.1 6.1e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase KR PF08659.5 EDN05754.1 - 2.6e-06 27.2 0.3 1.3e-05 24.9 0.0 2.3 2 1 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EDN05754.1 - 7.7e-06 25.8 0.0 2.4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EDN05754.1 - 0.012 15.4 0.0 0.069 12.9 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Lant_dehyd_C PF04738.8 EDN05754.1 - 0.23 9.6 0.0 0.4 8.8 0.0 1.3 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus Utp11 PF03998.8 EDN05755.1 - 1.3e-55 188.8 29.9 2.2e-55 188.1 20.7 1.3 1 0 0 1 1 1 1 Utp11 protein Cmc1 PF08583.5 EDN05756.1 - 3.9e-17 61.7 4.8 3.9e-17 61.7 3.3 2.0 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like U79_P34 PF03064.11 EDN05756.1 - 0.0048 16.4 4.3 0.0056 16.2 3.0 1.1 1 0 0 1 1 1 1 HSV U79 / HCMV P34 DUF4629 PF15442.1 EDN05756.1 - 0.34 11.0 4.8 0.45 10.6 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) Nucleo_P87 PF07267.6 EDN05756.1 - 1.4 7.5 6.5 1.5 7.4 4.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC27 PF09507.5 EDN05756.1 - 8.1 5.5 13.3 12 4.9 9.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIID-31kDa PF02291.10 EDN05757.1 - 1.1e-28 99.6 0.0 4.7e-14 52.2 0.0 3.1 3 0 0 3 3 3 3 Transcription initiation factor IID, 31kD subunit LNS2 PF08235.8 EDN05758.1 - 9e-71 236.5 0.0 1.7e-70 235.6 0.0 1.5 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EDN05758.1 - 1.3e-40 137.4 0.0 3.3e-40 136.2 0.0 1.7 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EDN05758.1 - 0.0044 16.4 0.0 0.15 11.4 0.0 2.4 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) AF1Q PF15017.1 EDN05758.1 - 0.64 9.9 11.1 0.13 12.1 0.6 2.8 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator RNA_pol_Rpb1_1 PF04997.7 EDN05761.1 - 1.4e-117 392.7 0.0 2.2e-117 392.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EDN05761.1 - 2.3e-105 351.7 0.1 3.7e-105 351.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EDN05761.1 - 3.5e-69 232.0 0.0 7.6e-69 230.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EDN05761.1 - 8.3e-64 214.7 1.3 1.8e-63 213.6 0.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EDN05761.1 - 3e-47 160.2 0.0 7.9e-47 158.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EDN05761.1 - 6.7e-43 145.6 8.3 1.5e-42 144.5 5.8 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EDN05761.1 - 5.9e-37 125.7 0.1 1.3e-36 124.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EDN05761.1 - 2.1e-09 36.7 193.1 0.12 12.5 5.9 14.2 11 2 4 15 15 15 9 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.27 EDN05762.1 - 0.00018 21.2 2.2 0.023 14.5 0.0 3.8 4 1 0 4 4 4 2 WD domain, G-beta repeat DDE_1 PF03184.14 EDN05764.1 - 3.9e-52 176.5 0.0 7.1e-52 175.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN05764.1 - 2.1e-11 43.4 0.0 7.8e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN05764.1 - 2.2e-10 39.9 0.2 5.5e-10 38.6 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN05764.1 - 5e-06 26.3 0.0 1.2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_18 PF12847.2 EDN05765.1 - 0.00025 21.5 0.0 0.00039 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN05765.1 - 0.00095 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EDN05765.1 - 0.0053 16.4 0.0 0.015 15.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EDN05765.1 - 0.024 13.6 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_31 PF13847.1 EDN05765.1 - 0.037 13.6 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EDN05765.1 - 0.095 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase WD40 PF00400.27 EDN05767.1 - 6.8e-17 60.6 3.3 2.8e-05 23.8 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EDN05767.1 - 0.064 11.3 0.0 0.27 9.3 0.0 1.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDN05767.1 - 0.072 11.8 0.0 9.4 4.8 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like Aldedh PF00171.17 EDN05768.1 - 3e-145 484.1 0.1 3.4e-145 483.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EDN05768.1 - 0.00017 20.4 0.0 0.0018 17.1 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) NAD_binding_4 PF07993.7 EDN05769.1 - 4.8e-39 133.7 0.0 1.1e-38 132.5 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 EDN05769.1 - 7.8e-37 126.6 0.5 4.8e-36 124.0 0.3 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EDN05769.1 - 9.9e-10 38.2 0.0 1.5e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EDN05769.1 - 1.8e-06 28.1 0.0 4.9e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EDN05769.1 - 0.037 12.9 0.0 0.66 8.8 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EDN05769.1 - 0.04 12.8 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EDN05769.1 - 0.071 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase Sel1 PF08238.7 EDN05770.1 - 9.5e-36 121.4 41.9 1.4e-05 25.5 0.1 13.1 13 0 0 13 13 13 8 Sel1 repeat TPR_14 PF13428.1 EDN05770.1 - 0.024 15.2 4.3 9.2 7.2 0.2 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDN05770.1 - 0.08 13.6 12.4 0.8 10.4 0.5 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Sigma54_AID PF00309.15 EDN05770.1 - 0.19 11.2 0.2 0.35 10.3 0.1 1.3 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) MBD PF01429.14 EDN05771.1 - 0.024 14.1 0.0 0.055 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyl-CpG binding domain FlxA PF14282.1 EDN05772.1 - 0.075 12.9 0.1 0.25 11.3 0.1 1.9 1 0 0 1 1 1 0 FlxA-like protein DUF4140 PF13600.1 EDN05772.1 - 0.1 13.0 2.1 0.32 11.4 0.1 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Uds1 PF15456.1 EDN05772.1 - 1.6 8.7 6.5 6.9 6.6 4.5 2.0 1 1 0 1 1 1 0 Up-regulated During Septation Pol_alpha_B_N PF08418.5 EDN05772.1 - 5.1 6.5 9.0 7.8 5.9 6.2 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Kelch_3 PF13415.1 EDN05773.1 - 5.2e-16 58.3 2.2 1.7e-07 31.1 0.0 3.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.1 EDN05773.1 - 3.3e-15 55.5 0.3 7e-08 32.1 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EDN05773.1 - 5.1e-12 45.4 0.3 6.2e-05 23.0 0.1 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 EDN05773.1 - 4.5e-11 42.4 0.7 9.5e-06 25.4 0.1 3.1 3 0 0 3 3 3 2 Kelch motif BTB PF00651.26 EDN05773.1 - 5.9e-10 39.1 0.1 1.1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.10 EDN05773.1 - 4.1e-09 35.8 0.1 3.5e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.20 EDN05773.1 - 1.6e-08 33.9 1.0 0.0047 16.4 0.2 2.5 2 0 0 2 2 2 2 Kelch motif WD40 PF00400.27 EDN05774.1 - 5.4e-23 79.9 16.3 2.1e-06 27.3 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EDN05774.1 - 0.00014 21.6 0.4 0.011 15.4 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A RVT_1 PF00078.22 EDN05776.1 - 6.3e-24 84.5 0.0 1.4e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EDN05776.1 - 0.00012 21.4 0.1 0.00035 19.9 0.0 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVP PF00077.15 EDN05776.1 - 0.02 14.7 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EDN05776.1 - 0.039 13.7 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDN05776.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease TFIIA PF03153.8 EDN05777.1 - 2.4e-88 297.5 35.5 1.3e-87 295.1 24.6 1.8 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cor1 PF04803.7 EDN05777.1 - 0.017 14.8 4.5 0.054 13.2 3.1 1.8 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region zf-C2H2_4 PF13894.1 EDN05778.1 - 2.5e-05 24.2 10.7 0.062 13.6 0.6 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN05778.1 - 0.00057 20.0 12.6 0.072 13.4 1.0 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EDN05778.1 - 0.00065 19.7 1.3 0.056 13.6 0.0 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EDN05778.1 - 0.0007 19.7 9.7 0.013 15.7 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain SprT-like PF10263.4 EDN05778.1 - 0.039 13.6 0.4 0.069 12.8 0.3 1.4 1 0 0 1 1 1 0 SprT-like family RNHCP PF12647.2 EDN05778.1 - 0.055 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 RNHCP domain Tetraspannin PF00335.15 EDN05778.1 - 0.23 10.6 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 Tetraspanin family Macoilin PF09726.4 EDN05778.1 - 0.73 8.0 1.9 1.4 7.1 1.4 1.3 1 0 0 1 1 1 0 Transmembrane protein zf-met PF12874.2 EDN05778.1 - 2 8.7 4.6 4.7 7.5 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Dus PF01207.12 EDN05780.1 - 5e-42 143.8 0.1 1.4e-29 102.8 0.3 3.0 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EDN05780.1 - 0.03 14.0 3.6 2.8 7.7 0.4 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Bap31 PF05529.7 EDN05781.1 - 7.5e-67 224.5 0.2 8.7e-67 224.3 0.1 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DivIC PF04977.10 EDN05781.1 - 0.0003 20.2 0.8 0.025 14.0 0.1 3.2 3 0 0 3 3 3 1 Septum formation initiator TMF_DNA_bd PF12329.3 EDN05781.1 - 0.0057 16.4 1.5 0.0057 16.4 1.0 1.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Mod_r PF07200.8 EDN05781.1 - 0.017 15.0 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Cast PF10174.4 EDN05781.1 - 0.025 12.6 1.1 0.034 12.2 0.8 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Spc7 PF08317.6 EDN05781.1 - 0.039 12.6 0.2 0.061 11.9 0.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein MbeD_MobD PF04899.7 EDN05781.1 - 0.079 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 MbeD/MobD like Phage_GP20 PF06810.6 EDN05781.1 - 0.082 12.3 0.9 0.12 11.7 0.6 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 SlyX PF04102.7 EDN05781.1 - 0.2 12.0 1.7 0.4 11.0 0.2 2.1 2 1 1 3 3 3 0 SlyX DUF1385 PF07136.6 EDN05781.1 - 9.1 5.2 8.2 7.7 5.5 4.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) DUF2404 PF10296.4 EDN05782.1 - 0.0042 17.1 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DDE_3 PF13358.1 EDN05783.1 - 1.1e-11 44.6 0.4 1.7e-11 44.0 0.3 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease T4_baseplate PF12322.3 EDN05783.1 - 0.023 13.9 0.1 0.025 13.8 0.1 1.1 1 0 0 1 1 1 0 T4 bacteriophage base plate protein Chromo PF00385.19 EDN05785.1 - 6e-05 22.6 2.8 0.084 12.5 0.2 3.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.20 EDN05787.1 - 9.6e-09 34.7 0.0 2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN05787.1 - 0.0087 15.8 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN05787.1 - 0.043 12.8 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase AAA PF00004.24 EDN05788.1 - 2.5e-06 27.7 0.0 1e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_trans PF02486.14 EDN05788.1 - 0.028 13.9 1.0 0.077 12.4 0.0 2.1 2 0 0 2 2 2 0 Replication initiation factor SET_assoc PF11767.3 EDN05788.1 - 0.042 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Act-Frag_cataly PF09192.5 EDN05788.1 - 0.044 12.7 0.1 0.14 11.1 0.0 1.8 2 0 0 2 2 2 0 Actin-fragmin kinase, catalytic POX PF07526.6 EDN05788.1 - 0.42 10.8 3.9 0.36 11.0 1.0 2.1 2 0 0 2 2 2 0 Associated with HOX PPV_E1_N PF00524.13 EDN05791.1 - 0.049 13.8 1.3 0.049 13.8 0.9 1.6 2 0 0 2 2 2 0 E1 Protein, N terminal domain BCS1_N PF08740.6 EDN05792.1 - 1.5e-40 138.8 0.0 2.5e-40 138.1 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN05792.1 - 4e-20 72.3 0.0 1.7e-19 70.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN05792.1 - 0.00062 19.8 0.1 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EDN05792.1 - 0.0068 15.8 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN05792.1 - 0.018 15.8 1.4 0.1 13.3 0.0 2.9 3 1 0 3 3 3 0 AAA domain KaiC PF06745.8 EDN05792.1 - 0.025 13.6 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.1 EDN05792.1 - 0.028 14.2 0.0 0.22 11.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EDN05792.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN05792.1 - 0.14 12.3 0.0 0.38 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDN05792.1 - 0.16 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Myb_DNA-binding PF00249.26 EDN05793.1 - 3.1e-13 49.5 4.8 9.4e-09 35.2 0.1 3.3 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN05793.1 - 1.4e-08 34.6 0.8 1.6e-05 24.9 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain WRC PF08879.5 EDN05794.1 - 0.07 12.8 0.3 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 WRC Lac_bphage_repr PF06543.7 EDN05794.1 - 0.13 11.8 1.5 0.38 10.3 1.0 1.7 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor DUF3435 PF11917.3 EDN05795.1 - 1.1e-162 541.6 0.0 1.3e-162 541.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Nipped-B_C PF12830.2 EDN05795.1 - 0.015 14.9 1.4 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus EVE PF01878.13 EDN05795.1 - 0.11 12.5 0.7 51 3.8 0.0 3.2 3 0 0 3 3 3 0 EVE domain zf-C2H2_4 PF13894.1 EDN05795.1 - 0.21 11.9 4.6 7.7 7.1 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN05795.1 - 3.5 8.1 5.8 18 5.9 0.2 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pkinase PF00069.20 EDN05797.1 - 1.9e-45 155.0 0.0 3.7e-45 154.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05797.1 - 2.2e-19 69.5 0.0 4.5e-14 52.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDN05797.1 - 3.4e-05 22.9 0.0 0.033 13.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EDN05797.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ank_2 PF12796.2 EDN05799.1 - 6.8e-45 151.3 0.3 2.3e-12 47.0 0.2 8.6 7 2 2 9 9 9 7 Ankyrin repeats (3 copies) Ank PF00023.25 EDN05799.1 - 2.1e-31 106.1 4.7 4.6e-05 23.0 0.0 10.5 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.1 EDN05799.1 - 6e-31 105.7 1.3 1.6e-06 28.1 0.0 12.1 12 1 2 14 14 14 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN05799.1 - 6.9e-28 96.5 3.1 1.6e-05 25.2 0.0 10.9 10 1 1 11 11 11 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN05799.1 - 7e-26 87.7 1.5 0.1 12.8 0.0 12.1 13 0 0 13 13 13 7 Ankyrin repeat Senescence PF06911.7 EDN05801.1 - 8.1e-50 168.9 4.3 1.1e-49 168.5 3.0 1.2 1 0 0 1 1 1 1 Senescence-associated protein Acyl-CoA_dh_1 PF00441.19 EDN05802.1 - 4.3e-40 137.2 9.0 5.5e-40 136.9 6.2 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EDN05802.1 - 1.1e-16 61.3 3.1 4.4e-16 59.4 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EDN05802.1 - 4.8e-16 59.2 5.3 6.9e-16 58.7 3.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SR-25 PF10500.4 EDN05803.1 - 1.6 8.1 8.4 1.9 7.9 5.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_capsid PF06112.6 EDN05803.1 - 7.2 6.6 9.2 8.4 6.4 6.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Cupin_2 PF07883.6 EDN05804.1 - 4.3e-05 22.9 0.0 7.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EDN05804.1 - 0.0012 18.2 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EDN05804.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) GWT1 PF06423.7 EDN05805.1 - 1.8e-45 154.3 1.3 4.8e-45 152.9 0.9 1.8 1 0 0 1 1 1 1 GWT1 Amidase PF01425.16 EDN05806.1 - 5.1e-79 266.1 0.1 6.5e-79 265.8 0.1 1.1 1 0 0 1 1 1 1 Amidase PDEase_II PF02112.10 EDN05807.1 - 6.8e-58 196.1 0.0 5.5e-48 163.6 0.0 3.0 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EDN05807.1 - 6.4e-05 22.5 0.0 0.00015 21.3 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EDN05807.1 - 0.00027 20.6 0.2 0.001 18.7 0.1 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DXP_redisom_C PF08436.7 EDN05807.1 - 0.16 11.8 0.0 0.62 9.9 0.0 1.9 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal SPRY PF00622.23 EDN05808.1 - 1e-13 51.4 0.1 1e-12 48.2 0.1 2.2 1 1 0 1 1 1 1 SPRY domain DUF4117 PF13491.1 EDN05808.1 - 0.016 14.6 1.3 0.025 14.0 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4117) Peptidase_M24 PF00557.19 EDN05810.1 - 8.2e-57 192.1 0.0 1.2e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EDN05810.1 - 2.2e-24 85.3 0.0 4.3e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Sec63 PF02889.11 EDN05812.1 - 6.7e-40 137.2 0.0 1.6e-37 129.3 0.0 2.7 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EDN05812.1 - 1e-15 57.1 0.3 2.4e-15 56.0 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 EDN05814.1 - 4e-11 42.2 0.4 8.4e-11 41.2 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain HMG_box PF00505.14 EDN05816.1 - 0.006 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box SAM_1 PF00536.25 EDN05816.1 - 0.0072 16.4 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EDN05816.1 - 0.008 15.9 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Pkinase PF00069.20 EDN05817.1 - 2.1e-21 76.2 0.0 7.3e-21 74.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN05817.1 - 0.006 15.6 0.0 0.33 9.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase ALO PF04030.9 EDN05819.1 - 5.1e-84 281.9 0.0 8.4e-84 281.2 0.0 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EDN05819.1 - 1.2e-30 105.7 0.0 1.8e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Gelsolin PF00626.17 EDN05820.1 - 2e-11 43.3 0.0 0.005 16.4 0.0 3.4 3 0 0 3 3 3 3 Gelsolin repeat DUF4045 PF13254.1 EDN05821.1 - 7.5e-121 404.3 24.3 7.5e-121 404.3 16.9 4.0 3 2 1 4 4 4 1 Domain of unknown function (DUF4045) Paralemmin PF03285.10 EDN05821.1 - 0.0034 16.9 1.5 0.0061 16.0 0.2 2.1 2 0 0 2 2 2 1 Paralemmin Arf PF00025.16 EDN05822.1 - 2.5e-66 222.2 0.8 2.8e-66 222.0 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EDN05822.1 - 1.8e-12 46.9 0.0 2.1e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EDN05822.1 - 9.4e-12 44.3 2.9 2.2e-07 29.8 0.6 2.7 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDN05822.1 - 5.2e-11 42.1 0.0 6.3e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EDN05822.1 - 7.8e-09 35.5 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDN05822.1 - 3.3e-08 34.0 0.0 4.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EDN05822.1 - 6.8e-08 32.1 0.0 3.3e-06 26.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EDN05822.1 - 1.6e-06 27.4 0.0 2.1e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_17 PF13207.1 EDN05822.1 - 0.044 14.6 0.1 0.065 14.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EDN05822.1 - 0.054 12.7 0.2 0.2 10.9 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.7 EDN05822.1 - 0.077 12.6 0.1 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Acetyltransf_3 PF13302.1 EDN05823.1 - 0.0069 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN05823.1 - 0.0088 16.0 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF1501 PF07394.7 EDN05823.1 - 0.02 13.7 0.1 0.037 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Acetyltransf_10 PF13673.1 EDN05823.1 - 0.06 13.4 0.0 0.21 11.7 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF605 PF04652.11 EDN05824.1 - 1.8 7.9 13.5 2.3 7.5 9.4 1.1 1 0 0 1 1 1 0 Vta1 like HMGL-like PF00682.14 EDN05825.1 - 1.5e-67 227.7 0.0 3.9e-66 223.1 0.0 2.4 2 0 0 2 2 2 1 HMGL-like DEAD PF00270.24 EDN05825.1 - 1.9e-44 151.1 0.0 8e-44 149.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN05825.1 - 6.9e-27 93.1 2.6 9.9e-26 89.4 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain LeuA_dimer PF08502.5 EDN05825.1 - 2.9e-11 43.3 0.5 1.6e-09 37.6 0.4 2.5 2 0 0 2 2 2 1 LeuA allosteric (dimerisation) domain DUF1253 PF06862.7 EDN05825.1 - 3.3e-05 22.5 0.3 0.00019 19.9 0.1 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF1253) DnaG_DnaB_bind PF08278.6 EDN05825.1 - 0.11 12.7 5.4 4.5 7.5 3.3 2.5 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding AMP-binding PF00501.23 EDN05826.1 - 4.2e-46 157.1 0.4 5.9e-25 87.5 0.0 3.7 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.6 EDN05826.1 - 4.5e-07 30.4 0.0 2.6e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 DMAP1-binding Domain GvpG PF05120.7 EDN05826.1 - 0.0066 16.2 0.5 0.02 14.6 0.4 1.8 1 0 0 1 1 1 1 Gas vesicle protein G SHOCT PF09851.4 EDN05826.1 - 0.58 9.7 1.7 1.1 8.8 1.2 1.5 1 0 0 1 1 1 0 Short C-terminal domain Ribosomal_S7 PF00177.16 EDN05827.1 - 2.5e-39 134.2 1.7 3.1e-39 133.9 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.7 EDN05828.1 - 1.2e-94 317.2 33.9 1.2e-94 317.2 23.5 2.3 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EDN05828.1 - 4.2e-23 81.3 0.1 1.2e-22 79.9 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain RAI1 PF08652.6 EDN05828.1 - 6.2 6.6 8.7 10 6.0 0.1 3.0 3 0 0 3 3 3 0 RAI1 like PD-(D/E)XK nuclease RNR_inhib PF08591.5 EDN05829.1 - 0.0016 19.3 1.7 0.0032 18.3 0.1 2.2 2 1 0 2 2 2 1 Ribonucleotide reductase inhibitor dDENN PF03455.14 EDN05829.1 - 0.053 13.5 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 dDENN domain Chlorosome_CsmC PF11098.3 EDN05830.1 - 0.18 11.5 1.6 0.52 10.0 0.0 2.1 2 0 0 2 2 2 0 Chlorosome envelope protein C vATP-synt_AC39 PF01992.11 EDN05831.1 - 3.2e-109 365.1 0.0 3.9e-109 364.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.13 EDN05832.1 - 3.6e-54 182.1 0.5 1.1e-53 180.6 0.3 1.9 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EDN05832.1 - 8.2e-27 92.7 0.1 1.4e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EDN05832.1 - 2.3e-21 75.7 1.7 2.3e-21 75.7 1.2 3.5 4 0 0 4 4 4 1 NOP5NT (NUC127) domain HTH_17 PF12728.2 EDN05832.1 - 0.033 14.4 0.1 0.11 12.7 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain Vpu PF00558.14 EDN05832.1 - 3.8 7.1 5.5 15 5.2 3.8 2.0 1 0 0 1 1 1 0 Vpu protein DUF4613 PF15390.1 EDN05832.1 - 9.8 4.2 9.7 15 3.6 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) RNA_pol_Rpb4 PF03874.11 EDN05833.1 - 1.7e-05 24.7 4.8 0.0047 16.9 0.3 2.4 3 0 0 3 3 3 2 RNA polymerase Rpb4 CaM_binding PF07839.6 EDN05833.1 - 0.071 13.3 0.1 0.15 12.3 0.1 1.5 1 1 0 1 1 1 0 Plant calmodulin-binding domain Secretin_N_2 PF07655.8 EDN05833.1 - 7.3 7.0 10.5 0.96 9.8 4.4 1.6 2 0 0 2 2 2 0 Secretin N-terminal domain DUF4131 PF13567.1 EDN05834.1 - 0.06 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PARP PF00644.15 EDN05836.1 - 6e-10 38.8 0.0 1.2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EDN05836.1 - 4.3e-08 32.7 0.0 1.2e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDN05836.1 - 0.0049 16.7 0.1 0.04 13.7 0.0 2.2 2 0 0 2 2 2 1 RWD domain Prok-E2_B PF14461.1 EDN05836.1 - 0.051 13.3 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic E2 family B adh_short PF00106.20 EDN05837.1 - 2.5e-24 86.0 0.0 3.5e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN05837.1 - 1.2e-09 38.2 0.0 1.7e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN05837.1 - 9.8e-08 31.8 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EDN05837.1 - 0.00011 21.4 0.0 0.0002 20.5 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) WD40 PF00400.27 EDN05838.1 - 1.1e-26 91.7 12.1 1.3e-08 34.4 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat PCI PF01399.22 EDN05839.1 - 5e-22 78.2 0.9 1.2e-21 77.0 0.1 2.0 2 0 0 2 2 2 1 PCI domain DDRGK PF09756.4 EDN05839.1 - 0.00025 20.5 0.3 0.0004 19.8 0.2 1.3 1 0 0 1 1 1 1 DDRGK domain TPR_12 PF13424.1 EDN05839.1 - 0.00026 20.8 12.3 0.44 10.5 0.6 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDN05839.1 - 0.00067 19.2 5.1 1.2 9.0 0.0 5.7 5 1 0 6 6 6 1 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EDN05839.1 - 0.0028 17.4 1.7 0.0049 16.6 0.4 1.9 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_8 PF13181.1 EDN05839.1 - 0.0036 16.9 4.1 22 5.1 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat UPF0302 PF08864.5 EDN05839.1 - 0.0066 16.2 0.2 0.015 15.0 0.1 1.6 1 0 0 1 1 1 1 UPF0302 domain TPR_2 PF07719.12 EDN05839.1 - 0.019 14.8 5.0 29 4.8 0.1 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDN05839.1 - 0.048 14.3 9.3 2.7 8.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EDN05839.1 - 0.065 13.6 0.1 1.6 9.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_22 PF13401.1 EDN05839.1 - 0.074 13.1 1.7 0.88 9.7 0.0 2.8 2 2 0 2 2 2 0 AAA domain TPR_14 PF13428.1 EDN05839.1 - 0.091 13.4 7.4 25 5.8 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat Med29 PF11568.3 EDN05839.1 - 0.092 12.8 0.2 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 Mediator complex subunit 29 TPR_1 PF00515.23 EDN05839.1 - 1.1 8.9 9.4 2.7 7.7 0.1 5.1 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.4 EDN05839.1 - 7.9 6.4 9.2 0.31 10.9 0.4 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDN05839.1 - 9.1 6.7 10.6 1.8 8.9 0.2 4.3 5 1 1 6 6 5 0 Tetratricopeptide repeat Mpv17_PMP22 PF04117.7 EDN05840.1 - 7.9e-14 51.0 0.4 9.9e-12 44.3 0.3 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family HTH_29 PF13551.1 EDN05841.1 - 1.3e-07 31.7 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.10 EDN05841.1 - 1.6e-07 31.0 0.0 4.2e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_33 PF13592.1 EDN05841.1 - 1.7e-06 27.4 0.0 4.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EDN05841.1 - 2.3e-06 27.0 0.5 0.00017 21.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 EDN05841.1 - 5.1e-05 22.7 0.0 0.00065 19.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.13 EDN05841.1 - 0.00012 21.8 0.0 0.00018 21.1 0.0 1.3 1 1 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.1 EDN05841.1 - 0.00027 20.8 0.0 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EDN05841.1 - 0.0033 18.2 0.0 0.017 15.9 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_IS630 PF01710.11 EDN05841.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Transposase GerE PF00196.14 EDN05841.1 - 0.056 12.7 0.9 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Terminase_5 PF06056.7 EDN05841.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Trp_repressor PF01371.14 EDN05841.1 - 0.13 12.1 0.1 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Trp repressor protein BSP_II PF05432.6 EDN05842.1 - 0.0026 17.0 9.1 0.0034 16.7 6.3 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Daxx PF03344.10 EDN05842.1 - 0.0046 15.5 10.9 0.0039 15.7 7.6 1.1 1 0 0 1 1 1 1 Daxx Family Nucleoplasmin PF03066.10 EDN05842.1 - 0.0051 16.3 10.7 0.0088 15.5 7.4 1.4 1 0 0 1 1 1 1 Nucleoplasmin DUF3381 PF11861.3 EDN05842.1 - 0.013 15.0 8.7 1.3 8.4 6.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) IFT57 PF10498.4 EDN05842.1 - 0.031 13.0 2.9 0.033 12.9 2.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Nop14 PF04147.7 EDN05842.1 - 0.043 11.7 8.9 0.044 11.7 6.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4246 PF14033.1 EDN05842.1 - 0.043 12.4 3.8 0.048 12.2 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) eIF-3c_N PF05470.7 EDN05842.1 - 0.046 11.8 3.7 0.046 11.8 2.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF1510 PF07423.6 EDN05842.1 - 0.052 12.9 6.5 0.066 12.5 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MYCBPAP PF14646.1 EDN05842.1 - 0.057 12.1 3.7 0.062 12.0 2.6 1.2 1 0 0 1 1 1 0 MYCBP-associated protein family FAM176 PF14851.1 EDN05842.1 - 0.084 12.5 5.4 0.12 12.0 3.7 1.3 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.11 EDN05842.1 - 0.13 11.2 5.3 0.16 10.9 3.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit VID27 PF08553.5 EDN05842.1 - 0.19 9.9 7.0 0.21 9.7 4.9 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Paf1 PF03985.8 EDN05842.1 - 0.26 10.0 12.0 0.35 9.5 8.3 1.2 1 0 0 1 1 1 0 Paf1 Pox_Ag35 PF03286.9 EDN05842.1 - 0.27 10.7 7.5 0.32 10.4 5.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ycf1 PF05758.7 EDN05842.1 - 0.3 8.7 2.3 0.29 8.8 1.6 1.0 1 0 0 1 1 1 0 Ycf1 Sigma70_ner PF04546.8 EDN05842.1 - 0.41 10.2 11.8 0.67 9.5 8.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region TFIIF_alpha PF05793.7 EDN05842.1 - 0.46 8.7 12.9 0.57 8.4 8.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YqfQ PF14181.1 EDN05842.1 - 0.48 10.4 5.3 0.72 9.8 3.6 1.4 1 0 0 1 1 1 0 YqfQ-like protein Herpes_gE PF02480.11 EDN05842.1 - 0.64 8.2 3.1 0.77 7.9 2.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CDC45 PF02724.9 EDN05842.1 - 0.7 7.8 7.2 0.78 7.6 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.6 EDN05842.1 - 0.84 9.4 8.0 1.3 8.7 5.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal HSP90 PF00183.13 EDN05842.1 - 1 7.6 11.9 1.5 7.1 8.2 1.2 1 0 0 1 1 1 0 Hsp90 protein PPP4R2 PF09184.6 EDN05842.1 - 1.7 8.0 16.3 2.8 7.4 11.3 1.3 1 0 0 1 1 1 0 PPP4R2 RNA_pol_Rpc4 PF05132.9 EDN05842.1 - 2.5 8.0 6.7 3.9 7.4 4.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 CobT PF06213.7 EDN05842.1 - 3.1 6.8 15.6 4.3 6.3 10.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT AF1Q PF15017.1 EDN05842.1 - 4.7 7.1 16.5 10 6.1 11.4 1.5 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Myc_N PF01056.13 EDN05842.1 - 4.7 6.2 13.2 7.4 5.6 9.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region NESP55 PF06390.7 EDN05842.1 - 4.9 6.4 24.9 0.15 11.3 2.1 2.1 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Sporozoite_P67 PF05642.6 EDN05842.1 - 7.2 4.3 9.3 9.6 3.9 6.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3682 PF12446.3 EDN05842.1 - 7.6 6.8 17.3 0.21 11.8 7.6 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF3682) Pox_RNA_Pol_19 PF05320.7 EDN05842.1 - 10 5.8 10.6 15 5.2 7.3 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Mt_ATP-synt_B PF05405.9 EDN05844.1 - 0.049 13.0 0.3 0.064 12.7 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2145 PF09916.4 EDN05844.1 - 0.066 12.7 0.1 0.08 12.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) DUF2462 PF09495.5 EDN05844.1 - 0.092 13.4 0.2 0.14 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) RVT_1 PF00078.22 EDN05845.1 - 6.4e-35 120.4 0.0 9.6e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN05845.1 - 1.5e-15 56.8 0.0 3.9e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN05845.1 - 0.00078 19.4 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF837 PF05769.6 EDN05846.1 - 0.018 14.6 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF837) PEX11 PF05648.9 EDN05847.1 - 2.6e-14 53.0 0.0 6.3e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) AAA PF00004.24 EDN05849.1 - 1.4e-95 316.5 0.0 5e-47 159.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EDN05849.1 - 4.5e-18 64.9 0.5 1.1e-17 63.6 0.3 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EDN05849.1 - 1.8e-13 50.7 0.0 3.2e-07 30.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EDN05849.1 - 5.2e-13 49.0 0.0 3.4e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EDN05849.1 - 2.5e-12 46.3 0.0 9.1e-05 21.6 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EDN05849.1 - 1.8e-11 43.9 0.4 1.1e-05 25.1 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EDN05849.1 - 2.1e-11 44.7 0.0 0.00035 21.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EDN05849.1 - 5.8e-11 42.6 0.2 0.0035 17.5 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EDN05849.1 - 1.3e-09 38.3 0.3 0.0018 18.3 0.0 4.1 3 2 1 4 4 4 2 AAA ATPase domain TIP49 PF06068.8 EDN05849.1 - 3.7e-08 32.4 0.1 0.0064 15.2 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EDN05849.1 - 8.2e-08 31.8 0.0 0.0049 16.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EDN05849.1 - 1.2e-07 31.3 1.2 0.0047 16.6 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 EDN05849.1 - 1.6e-07 31.2 0.0 0.0077 16.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EDN05849.1 - 2.3e-07 30.1 0.0 0.0045 16.1 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EDN05849.1 - 7.1e-07 28.8 6.5 0.019 14.3 0.0 4.6 3 2 2 5 5 4 2 AAA domain Mg_chelatase PF01078.16 EDN05849.1 - 7.8e-07 28.4 0.3 0.027 13.6 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EDN05849.1 - 1.3e-06 28.5 0.0 0.025 14.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EDN05849.1 - 3.3e-06 27.4 0.0 0.062 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EDN05849.1 - 5e-06 26.4 0.0 0.0094 15.8 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit PhoH PF02562.11 EDN05849.1 - 1.2e-05 24.6 0.3 0.14 11.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_28 PF13521.1 EDN05849.1 - 1.3e-05 25.2 0.0 0.17 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 EDN05849.1 - 2.2e-05 23.6 1.3 0.53 9.3 0.0 3.4 2 1 1 3 3 3 1 KaiC ABC_tran PF00005.22 EDN05849.1 - 4.3e-05 23.8 0.0 0.22 11.8 0.0 3.3 2 1 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 EDN05849.1 - 4.3e-05 23.5 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 EDN05849.1 - 7.2e-05 22.5 0.0 0.63 9.6 0.0 3.4 4 0 0 4 4 4 2 Bacterial dnaA protein AAA_24 PF13479.1 EDN05849.1 - 0.00011 21.8 0.4 0.14 11.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 EDN05849.1 - 0.00012 21.8 0.1 10 5.7 0.0 3.9 2 2 2 4 4 4 0 Archaeal ATPase Parvo_NS1 PF01057.12 EDN05849.1 - 0.00016 20.6 0.1 0.083 11.7 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EDN05849.1 - 0.00016 21.1 0.1 1.3 8.4 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Vps4_C PF09336.5 EDN05849.1 - 0.00027 20.7 0.1 0.0015 18.3 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.8 EDN05849.1 - 0.00031 19.7 0.0 0.03 13.2 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.7 EDN05849.1 - 0.00075 19.1 0.1 0.78 9.3 0.0 3.3 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 EDN05849.1 - 0.00079 18.5 0.0 0.58 9.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EDN05849.1 - 0.0014 18.2 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EDN05849.1 - 0.0016 18.0 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EDN05849.1 - 0.0018 18.0 0.2 1 9.0 0.0 3.5 3 0 0 3 3 3 1 NTPase AAA_30 PF13604.1 EDN05849.1 - 0.0019 17.8 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EDN05849.1 - 0.0025 16.7 0.0 0.59 8.9 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.13 EDN05849.1 - 0.0094 15.4 0.0 0.54 9.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EDN05849.1 - 0.018 14.5 0.9 10 5.4 0.0 3.7 3 1 1 4 4 4 0 AAA-like domain KAP_NTPase PF07693.9 EDN05849.1 - 0.018 14.0 0.0 1 8.2 0.0 2.7 2 1 0 3 3 3 0 KAP family P-loop domain IPT PF01745.11 EDN05849.1 - 0.062 12.4 0.1 5.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase SKI PF01202.17 EDN05849.1 - 0.1 12.4 0.1 8.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase Zot PF05707.7 EDN05849.1 - 0.11 11.9 0.4 33 3.8 0.1 3.8 4 1 0 4 4 3 0 Zonular occludens toxin (Zot) PIF1 PF05970.9 EDN05849.1 - 0.11 11.3 0.0 13 4.5 0.0 2.5 2 0 0 2 2 2 0 PIF1-like helicase RA PF00788.18 EDN05850.1 - 2.1e-15 56.9 0.0 6.4e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 EDN05850.1 - 7.3e-15 54.5 0.0 1.3e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EDN05850.1 - 9.1e-13 48.1 0.0 1.7e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 EDN05850.1 - 0.09 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 IGR protein motif Nha1_C PF08619.5 EDN05851.1 - 1.2e-101 341.1 24.8 2.4e-101 340.1 17.2 1.5 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EDN05851.1 - 9.7e-65 218.5 21.3 1.2e-64 218.2 14.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EDN05851.1 - 0.071 13.0 1.1 0.27 11.1 0.8 2.0 1 0 0 1 1 1 0 YrhC-like protein PX PF00787.19 EDN05852.1 - 1.9e-16 59.8 0.4 4.9e-16 58.5 0.2 1.7 1 0 0 1 1 1 1 PX domain AAA PF00004.24 EDN05852.1 - 1e-08 35.4 0.0 1.6e-07 31.5 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EDN05852.1 - 9.3e-06 24.5 0.0 4.5e-05 22.3 0.0 2.1 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EDN05852.1 - 6.1e-05 23.8 0.1 0.00024 21.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EDN05852.1 - 0.00023 21.1 0.0 0.0011 18.9 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN05852.1 - 0.00089 19.4 0.0 0.0031 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN05852.1 - 0.00092 18.9 0.0 0.0028 17.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 EDN05852.1 - 0.0031 16.4 0.0 0.0068 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EDN05852.1 - 0.0046 16.8 0.7 0.35 10.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EDN05852.1 - 0.0089 14.7 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EDN05852.1 - 0.034 13.1 0.0 0.09 11.8 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EDN05852.1 - 0.039 13.6 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EDN05852.1 - 0.056 13.7 0.0 0.22 11.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain Tmemb_cc2 PF10267.4 EDN05852.1 - 0.069 11.7 0.4 0.16 10.5 0.3 1.5 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein NTPase_1 PF03266.10 EDN05852.1 - 0.1 12.3 0.0 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 EDN05852.1 - 0.11 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EDN05852.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Prefoldin_3 PF13758.1 EDN05852.1 - 0.67 9.7 2.8 0.5 10.1 0.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit zf-C2H2 PF00096.21 EDN05854.1 - 3.3e-09 36.5 16.4 0.00013 22.0 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDN05854.1 - 4.6e-06 26.6 7.4 4.6e-06 26.6 5.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain Fungal_trans PF04082.13 EDN05854.1 - 0.00034 19.5 0.1 0.086 11.6 0.1 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EDN05854.1 - 0.046 14.0 22.1 0.09 13.1 2.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger WD40 PF00400.27 EDN05856.1 - 1.3e-21 75.5 0.7 5.7e-08 32.3 0.1 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EDN05856.1 - 6.8e-19 67.5 0.0 1.5e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Pinin_SDK_N PF04697.8 EDN05856.1 - 0.027 14.5 0.3 0.05 13.6 0.2 1.4 1 0 0 1 1 1 0 pinin/SDK conserved region Suf PF05843.9 EDN05857.1 - 0.089 12.5 7.4 0.11 12.1 5.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 EDN05857.1 - 2.5 7.3 18.0 3.2 7.0 12.5 1.1 1 0 0 1 1 1 0 Vta1 like BAF1_ABF1 PF04684.8 EDN05857.1 - 3.4 6.4 10.1 5.9 5.6 7.0 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 EDN05857.1 - 4.5 5.3 19.9 5.5 5.0 13.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Transglut_core PF01841.14 EDN05858.1 - 1.6e-13 50.8 0.0 3.2e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 EDN05858.1 - 0.031 13.5 0.0 0.37 10.0 0.0 2.2 1 1 0 1 1 1 0 Transglutaminase-like domain HTH_23 PF13384.1 EDN05860.1 - 0.075 12.7 0.1 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.1 EDN05860.1 - 0.13 11.8 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EDN05860.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 Sugar_tr PF00083.19 EDN05861.1 - 3.2e-101 339.1 17.0 5.7e-101 338.3 11.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN05861.1 - 8.9e-26 90.4 56.4 8.4e-23 80.6 18.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EDN05861.1 - 0.00053 18.5 2.9 0.00053 18.5 2.0 3.3 3 1 0 3 3 3 2 MFS/sugar transport protein SET PF00856.23 EDN05862.1 - 3.5e-08 33.9 0.0 6.1e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 SET domain Zn_clus PF00172.13 EDN05863.1 - 9.1e-07 28.6 12.4 1.9e-06 27.6 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EDN05864.1 - 7.6e-11 41.6 0.1 4.7e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Prenyltrans_1 PF13243.1 EDN05865.1 - 0.0034 17.3 0.1 0.008 16.1 0.1 1.8 1 1 1 2 2 2 1 Prenyltransferase-like Prenyltrans PF00432.16 EDN05865.1 - 0.044 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat DUF1680 PF07944.7 EDN05866.1 - 2.5e-13 49.1 0.0 3.2e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) TRAM_LAG1_CLN8 PF03798.11 EDN05867.1 - 1.5e-34 119.2 16.7 3.1e-34 118.2 11.6 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EDN05867.1 - 7.2e-24 83.0 0.4 1.6e-23 81.9 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein TFIIF_alpha PF05793.7 EDN05868.1 - 0.51 8.6 20.2 0.54 8.5 14.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TIP120 PF08623.5 EDN05869.1 - 3.3e-62 209.0 0.5 1.7e-58 196.9 0.0 4.3 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EDN05869.1 - 4.5e-19 68.5 16.2 0.00019 21.6 0.0 8.1 6 3 2 8 8 8 6 HEAT repeats HEAT PF02985.17 EDN05869.1 - 8e-15 53.5 13.3 0.05 13.6 0.0 10.8 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.1 EDN05869.1 - 4.9e-06 26.8 25.4 5.6 7.5 0.0 12.2 12 2 3 15 15 14 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EDN05869.1 - 9.7e-05 22.6 0.2 0.31 11.4 0.0 5.4 6 1 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EDN05869.1 - 0.00016 20.1 7.2 2.2 6.4 0.1 6.2 4 3 1 6 6 6 2 Adaptin N terminal region Cnd1 PF12717.2 EDN05869.1 - 0.00034 20.5 0.2 0.012 15.4 0.0 3.7 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EDN05869.1 - 0.0011 18.8 0.1 0.0011 18.8 0.1 3.9 5 0 0 5 5 5 1 Protein of unknown function (DUF2435) HEAT_PBS PF03130.11 EDN05869.1 - 0.002 18.4 0.2 0.29 11.7 0.1 4.8 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat ParcG PF10274.4 EDN05869.1 - 0.012 15.5 4.2 25 4.6 0.0 5.5 5 1 1 6 6 6 0 Parkin co-regulated protein UME PF08064.8 EDN05869.1 - 0.014 15.3 4.3 0.073 13.0 0.0 4.2 6 0 0 6 6 5 0 UME (NUC010) domain CLASP_N PF12348.3 EDN05869.1 - 0.059 12.7 0.1 1.6 7.9 0.0 3.4 4 0 0 4 4 4 0 CLASP N terminal PalH PF08733.5 EDN05874.1 - 1.6e-91 306.7 0.7 2e-91 306.4 0.5 1.1 1 0 0 1 1 1 1 PalH/RIM21 SSrecog PF03531.9 EDN05875.1 - 0.015 14.6 0.0 0.052 12.8 0.0 1.7 2 0 0 2 2 2 0 Structure-specific recognition protein (SSRP1) F-box-like PF12937.2 EDN05875.1 - 0.028 14.1 0.4 0.028 14.1 0.3 2.1 2 0 0 2 2 2 0 F-box-like DUF605 PF04652.11 EDN05875.1 - 1.3 8.2 25.5 2.3 7.5 17.7 1.3 1 0 0 1 1 1 0 Vta1 like Zip PF02535.17 EDN05876.1 - 0.0054 15.7 2.0 0.0086 15.1 1.4 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter Atg14 PF10186.4 EDN05878.1 - 9.9e-29 100.2 0.7 1.6e-28 99.5 0.5 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF4391 PF14335.1 EDN05878.1 - 0.0011 18.4 0.3 0.0024 17.3 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4391) Sec8_exocyst PF04048.9 EDN05878.1 - 0.0081 15.7 6.2 0.81 9.3 0.1 2.3 1 1 1 2 2 2 2 Sec8 exocyst complex component specific domain FH2 PF02181.18 EDN05878.1 - 0.026 13.4 4.4 0.046 12.5 3.1 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain AAA_13 PF13166.1 EDN05878.1 - 0.08 11.3 5.9 0.12 10.7 4.1 1.2 1 0 0 1 1 1 0 AAA domain CDRT4 PF15213.1 EDN05878.1 - 0.083 12.9 2.3 0.21 11.6 1.6 1.6 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein DUF607 PF04678.8 EDN05878.1 - 0.092 12.6 0.4 0.23 11.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Snapin_Pallidin PF14712.1 EDN05878.1 - 1.4 9.3 9.5 0.53 10.6 4.7 1.8 2 0 0 2 2 2 0 Snapin/Pallidin Mhr1 PF12829.2 EDN05879.1 - 7.1e-32 109.1 0.1 1.6e-31 107.9 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination CDC45 PF02724.9 EDN05879.1 - 3.3 5.6 12.8 6.1 4.7 8.9 1.4 1 0 0 1 1 1 0 CDC45-like protein PP2C PF00481.16 EDN05880.1 - 5.2e-64 216.0 0.0 6.1e-52 176.5 0.0 3.2 2 1 0 2 2 2 2 Protein phosphatase 2C AKAP7_RIRII_bdg PF10470.4 EDN05880.1 - 2.6 7.9 5.5 2 8.2 0.3 3.0 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein Snf7 PF03357.16 EDN05881.1 - 4.5e-35 120.5 19.3 2.6e-34 118.0 13.1 1.9 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 EDN05881.1 - 0.0099 13.7 3.9 0.012 13.5 2.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Ist1 PF03398.9 EDN05881.1 - 0.13 11.6 5.7 0.2 11.0 4.0 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF1043 PF06295.7 EDN05881.1 - 0.98 9.0 5.7 3.9 7.1 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF2205 PF10224.4 EDN05882.1 - 0.0069 15.9 0.5 0.017 14.6 0.3 1.6 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Poty_PP PF08440.5 EDN05882.1 - 0.11 11.5 2.0 0.33 9.9 0.1 2.2 2 0 0 2 2 2 0 Potyviridae polyprotein TMF_TATA_bd PF12325.3 EDN05882.1 - 0.76 9.5 7.2 2.1 8.0 0.8 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding PTCB-BRCT PF12738.2 EDN05883.1 - 7.8e-45 150.5 0.5 6.7e-23 80.3 0.1 3.4 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 EDN05883.1 - 1e-26 92.8 0.2 1.6e-11 44.1 0.0 4.0 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PIF1 PF05970.9 EDN05884.1 - 5.3e-62 209.8 0.6 6.2e-49 166.8 0.1 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EDN05884.1 - 5.9e-19 68.4 0.0 1.3e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDN05884.1 - 1.4e-08 34.9 0.0 3.4e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN05884.1 - 5.9e-06 25.9 0.1 1.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EDN05884.1 - 4.5e-05 23.5 0.3 0.00049 20.2 0.2 2.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EDN05884.1 - 7.2e-05 20.7 0.1 0.00042 18.2 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA PF00004.24 EDN05884.1 - 0.00019 21.6 0.1 0.00053 20.1 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EDN05884.1 - 0.00079 18.7 0.2 0.014 14.6 0.0 2.4 1 1 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.1 EDN05884.1 - 0.00093 19.2 0.7 0.005 16.8 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 EDN05884.1 - 0.0014 18.7 0.1 0.01 16.0 0.0 2.5 3 0 0 3 3 1 1 RNA helicase UvrD-helicase PF00580.16 EDN05884.1 - 0.0014 17.9 0.4 0.0032 16.8 0.1 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_14 PF13173.1 EDN05884.1 - 0.0016 18.3 0.2 0.0074 16.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 EDN05884.1 - 0.0018 17.2 0.5 0.0038 16.1 0.1 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF2075 PF09848.4 EDN05884.1 - 0.0044 16.0 0.0 0.0094 14.9 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EDN05884.1 - 0.0046 16.4 0.8 2.3 7.7 0.1 3.4 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.4 EDN05884.1 - 0.0079 14.8 0.1 0.015 13.9 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 EDN05884.1 - 0.017 14.2 0.0 0.04 13.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EDN05884.1 - 0.018 14.7 0.9 0.045 13.4 0.6 1.7 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EDN05884.1 - 0.026 14.1 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EDN05884.1 - 0.042 12.6 0.0 0.078 11.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.21 EDN05884.1 - 0.06 12.8 0.1 0.39 10.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain MobB PF03205.9 EDN05884.1 - 0.06 13.0 0.1 0.18 11.4 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EDN05884.1 - 0.061 12.4 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EDN05884.1 - 0.068 13.4 0.2 0.22 11.7 0.2 2.1 1 1 0 1 1 1 0 ABC transporter AAA_11 PF13086.1 EDN05884.1 - 0.077 12.5 0.0 0.077 12.5 0.0 3.1 4 1 0 4 4 4 0 AAA domain AAA_5 PF07728.9 EDN05884.1 - 0.081 12.6 0.7 1.1 9.0 0.5 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) APH PF01636.18 EDN05885.1 - 0.003 17.3 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YjeF_N PF03853.10 EDN05886.1 - 4.1e-32 111.1 0.1 6.2e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EDN05886.1 - 4.6e-10 39.9 5.7 4.6e-10 39.9 4.0 2.2 2 0 0 2 2 2 1 FDF domain NTP_transferase PF00483.18 EDN05886.1 - 0.021 14.1 0.0 0.069 12.4 0.0 1.7 2 0 0 2 2 2 0 Nucleotidyl transferase Pro_isomerase PF00160.16 EDN05887.1 - 1.6e-37 129.1 0.0 3.3e-37 128.1 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EDN05887.1 - 5.2e-06 25.8 2.1 1.3e-05 24.5 1.5 1.7 1 1 0 1 1 1 1 Rtf2 RING-finger Peptidase_C97 PF05903.9 EDN05888.1 - 1.1e-33 116.1 0.0 1.8e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 EDN05888.1 - 4.2e-31 107.7 0.0 5.8e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 EDN05888.1 - 9.6e-17 60.5 0.0 1.7e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EDN05888.1 - 3.7e-05 23.8 0.2 0.0002 21.4 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EDN05888.1 - 0.00025 20.8 0.0 0.00067 19.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.1 EDN05888.1 - 0.00063 19.2 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF2847 PF11009.3 EDN05888.1 - 0.0059 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Redoxin PF08534.5 EDN05888.1 - 0.047 13.2 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.1 EDN05888.1 - 0.052 13.1 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DIM1 PF02966.11 EDN05888.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 EF-hand_8 PF13833.1 EDN05889.1 - 0.026 14.1 0.0 11 5.7 0.0 2.6 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_9 PF14658.1 EDN05889.1 - 0.061 13.2 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain UCH PF00443.24 EDN05890.1 - 9.6e-09 34.7 0.0 1.9e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FA_desaturase PF00487.19 EDN05890.1 - 0.034 13.5 0.1 0.054 12.9 0.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF3509 PF12021.3 EDN05890.1 - 0.036 13.8 1.3 0.28 10.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) Alb1 PF09135.6 EDN05891.1 - 1.2e-28 99.9 9.5 2.2e-28 99.0 6.6 1.4 1 0 0 1 1 1 1 Alb1 DUF4410 PF14366.1 EDN05891.1 - 0.097 12.4 4.2 0.068 12.8 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) ABC_tran_2 PF12848.2 EDN05891.1 - 0.77 9.6 6.4 2.3 8.1 4.4 1.7 1 0 0 1 1 1 0 ABC transporter SLX9 PF15341.1 EDN05891.1 - 1.8 9.0 11.6 6.6 7.2 8.0 1.9 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 Vps16_N PF04841.8 EDN05892.1 - 4.8e-102 341.5 0.0 7.7e-102 340.8 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EDN05892.1 - 1.1e-65 221.6 0.0 1.8e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Bestrophin PF01062.16 EDN05895.1 - 4.6e-40 137.3 0.8 1.2e-24 86.8 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel FHA PF00498.21 EDN05896.1 - 1e-13 51.2 0.0 1.7e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EDN05896.1 - 8.3e-06 25.5 10.5 1.8e-05 24.4 7.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDN05896.1 - 0.00079 19.4 5.0 0.0017 18.4 3.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EDN05896.1 - 0.012 15.2 7.6 0.024 14.3 5.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 EDN05896.1 - 0.015 15.0 1.8 0.032 14.0 1.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-H2C2_2 PF13465.1 EDN05896.1 - 0.021 15.1 0.3 0.021 15.1 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-C3HC4 PF00097.20 EDN05896.1 - 0.15 11.7 9.4 0.34 10.6 6.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN05896.1 - 0.3 11.1 10.7 0.62 10.1 7.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EDN05896.1 - 0.81 9.7 7.2 1.6 8.7 5.0 1.5 1 0 0 1 1 1 0 RING-like domain DUF3722 PF12519.3 EDN05898.1 - 2.7e-87 292.2 0.4 3.6e-87 291.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Ribosomal_L10 PF00466.15 EDN05899.1 - 3e-17 62.3 0.0 5e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Terminase_1 PF03354.10 EDN05899.1 - 0.081 11.3 0.0 0.15 10.4 0.0 1.3 1 1 0 1 1 1 0 Phage Terminase U1snRNP70_N PF12220.3 EDN05900.1 - 2.5e-34 117.4 1.3 3.7e-34 116.9 0.9 1.3 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EDN05900.1 - 2.6e-16 59.0 0.1 7.6e-16 57.5 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN05900.1 - 6.5e-12 45.2 0.0 1.1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN05900.1 - 7.4e-07 28.9 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L51_S25_CI-B8 PF05047.11 EDN05901.1 - 2.8e-15 55.7 0.1 4.1e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain zf-RING_5 PF14634.1 EDN05902.1 - 0.0052 16.4 2.7 0.01 15.5 1.9 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EDN05902.1 - 0.01 15.6 2.4 0.023 14.5 1.7 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDN05902.1 - 0.015 15.3 7.1 0.093 12.7 4.9 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EDN05902.1 - 0.19 11.6 3.8 0.32 10.9 2.7 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.20 EDN05902.1 - 0.23 11.1 5.1 3.6 7.3 4.3 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN05902.1 - 0.98 9.1 7.1 3.2 7.4 4.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prp19 PF08606.6 EDN05903.1 - 1.7e-32 110.9 1.2 4.4e-32 109.6 0.8 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EDN05903.1 - 1.4e-16 59.6 4.7 1.3e-06 28.0 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EDN05903.1 - 1.4e-07 31.4 0.6 0.069 12.8 0.0 3.4 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 EDN05903.1 - 0.011 13.9 0.0 0.019 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) zf-Nse PF11789.3 EDN05903.1 - 0.015 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cytochrom_D1 PF02239.11 EDN05903.1 - 0.026 12.8 0.1 0.16 10.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF4604 PF15377.1 EDN05904.1 - 2.8e-24 86.1 6.3 3.2e-24 85.9 4.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) GTP_EFTU PF00009.22 EDN05905.1 - 4.6e-38 130.5 0.8 1.3e-37 129.0 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 EDN05905.1 - 1.2e-08 34.8 0.0 4.1e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EDN05905.1 - 3.7e-07 29.9 0.0 8e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EDN05905.1 - 6.1e-05 22.5 0.0 0.0037 16.8 0.0 2.6 2 0 0 2 2 2 1 Elongation factor G, domain IV D123 PF07065.9 EDN05905.1 - 0.021 13.8 0.3 0.057 12.4 0.2 1.7 1 0 0 1 1 1 0 D123 EXOSC1 PF10447.4 EDN05906.1 - 2.5e-28 97.8 0.1 4.8e-28 96.9 0.1 1.5 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EDN05906.1 - 1.7e-14 52.7 0.1 2.8e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Arm PF00514.18 EDN05907.1 - 7.9e-51 168.2 20.4 3.1e-12 45.8 0.1 8.9 9 1 1 10 10 10 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EDN05907.1 - 2.4e-20 72.6 11.2 9.9e-07 28.9 0.2 6.6 3 2 1 5 5 5 4 HEAT repeats HEAT PF02985.17 EDN05907.1 - 2.2e-18 64.6 8.8 0.059 13.4 0.1 7.8 8 0 0 8 8 8 5 HEAT repeat HEAT_EZ PF13513.1 EDN05907.1 - 6.8e-16 58.2 9.4 0.0015 18.9 0.0 7.3 6 1 2 8 8 7 6 HEAT-like repeat Adaptin_N PF01602.15 EDN05907.1 - 5.9e-10 38.0 8.0 3.4e-08 32.2 0.4 2.9 2 1 1 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.8 EDN05907.1 - 1.4e-05 24.3 8.5 0.0001 21.4 2.8 2.5 1 1 1 2 2 2 2 Armadillo-like KAP PF05804.7 EDN05907.1 - 1.8e-05 22.9 1.5 3.2e-05 22.0 0.7 1.5 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EDN05907.1 - 6.5e-05 22.1 2.2 0.0023 17.1 1.4 2.5 1 1 0 1 1 1 1 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 EDN05907.1 - 0.019 15.3 0.4 0.9 9.9 0.1 3.2 1 1 3 4 4 4 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 EDN05907.1 - 0.025 15.0 5.2 90 3.9 0.0 6.3 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 EDN05907.1 - 0.032 14.1 2.7 12 5.8 0.4 3.3 1 1 3 4 4 4 0 V-ATPase subunit H TIM PF00121.13 EDN05908.1 - 1.1e-28 99.9 0.0 1.3e-28 99.7 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase FAM92 PF06730.6 EDN05910.1 - 0.063 12.6 3.9 0.086 12.1 2.7 1.2 1 0 0 1 1 1 0 FAM92 protein Kdo PF06293.9 EDN05911.1 - 0.00014 21.0 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN05911.1 - 0.00017 21.4 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EDN05911.1 - 0.00061 19.0 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EDN05911.1 - 0.009 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EDN05911.1 - 0.15 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinesin PF00225.18 EDN05912.1 - 1.9e-114 381.8 0.0 1.9e-114 381.8 0.0 1.4 2 0 0 2 2 2 1 Kinesin motor domain DUF1643 PF07799.7 EDN05912.1 - 0.065 12.9 0.0 0.25 11.0 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) DUF87 PF01935.12 EDN05912.1 - 1.8 8.3 6.7 0.66 9.7 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF87 LMBR1 PF04791.11 EDN05912.1 - 2.2 6.7 3.8 2.4 6.6 0.7 1.9 2 0 0 2 2 2 0 LMBR1-like membrane protein IF-2B PF01008.12 EDN05913.1 - 1.8e-76 256.8 0.1 2.4e-76 256.4 0.1 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family NARP1 PF12569.3 EDN05913.1 - 0.81 8.3 2.6 1.3 7.6 1.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Apc13p PF05839.6 EDN05914.1 - 5e-20 71.2 1.2 1.8e-17 63.0 0.0 2.2 2 1 0 2 2 2 2 Apc13p protein Pol_alpha_B_N PF08418.5 EDN05915.1 - 9.5e-45 153.1 0.0 1.3e-44 152.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EDN05915.1 - 3.7e-32 111.2 0.0 5.6e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CRAL_TRIO PF00650.15 EDN05916.1 - 1.9e-35 121.6 0.0 2.5e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDN05916.1 - 9.5e-12 44.8 0.1 2.8e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EDN05916.1 - 0.00011 22.0 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HrpB_C PF08482.5 EDN05916.1 - 0.098 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 ATP-dependent helicase C-terminal CBS PF00571.23 EDN05917.1 - 9.8e-27 92.4 7.0 5.4e-12 45.2 0.1 4.3 4 0 0 4 4 4 4 CBS domain ECH PF00378.15 EDN05921.1 - 9.6e-05 21.6 0.0 0.00029 20.0 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Ribosomal_L4 PF00573.17 EDN05922.1 - 3.7e-21 75.3 0.0 4.5e-21 75.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.15 EDN05923.1 - 7.3e-14 51.8 0.0 9.8e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_S24 PF00717.18 EDN05924.1 - 3.6e-07 29.7 0.0 4.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase S24-like Lactamase_B PF00753.22 EDN05927.1 - 1.5e-18 67.1 1.6 3.2e-17 62.8 0.4 2.1 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily BcrAD_BadFG PF01869.15 EDN05927.1 - 0.002 17.4 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family DDE_3 PF13358.1 EDN05928.1 - 0.0006 19.5 0.1 0.00095 18.9 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_hydro_35 PF01301.14 EDN05928.1 - 0.034 13.5 0.3 0.052 12.9 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 HTH_Tnp_Tc3_2 PF01498.13 EDN05929.1 - 6.2e-27 93.4 0.0 1.1e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EDN05929.1 - 0.00052 20.7 0.2 0.0012 19.5 0.0 1.7 2 1 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EDN05929.1 - 0.0016 18.6 0.0 0.0026 17.9 0.0 1.4 1 1 0 1 1 1 1 Winged helix-turn helix HTH_21 PF13276.1 EDN05929.1 - 0.0024 17.8 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 HTH-like domain HTH_23 PF13384.1 EDN05929.1 - 0.029 14.0 0.0 0.88 9.3 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_10 PF04967.7 EDN05929.1 - 0.061 12.9 0.1 2.9 7.5 0.0 2.6 2 2 0 2 2 2 0 HTH DNA binding domain HTH_33 PF13592.1 EDN05929.1 - 0.12 11.9 0.1 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix RR_TM4-6 PF06459.7 EDN05930.1 - 2.5e-05 24.3 18.0 3.4e-05 23.8 12.5 1.3 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 BSMAP PF12280.3 EDN05930.1 - 0.00053 19.9 4.2 0.00065 19.6 2.9 1.2 1 0 0 1 1 1 1 Brain specific membrane anchored protein DUF2207 PF09972.4 EDN05930.1 - 0.0008 18.1 8.2 0.0012 17.5 5.7 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Suf PF05843.9 EDN05930.1 - 0.0011 18.7 8.2 0.0012 18.5 5.7 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) VIT1 PF01988.14 EDN05930.1 - 0.0021 17.5 0.2 0.003 17.0 0.1 1.1 1 0 0 1 1 1 1 VIT family Ctr PF04145.10 EDN05930.1 - 0.0028 17.7 0.6 0.0047 16.9 0.4 1.4 1 0 0 1 1 1 1 Ctr copper transporter family Ycf1 PF05758.7 EDN05930.1 - 0.0036 15.1 17.3 0.0038 15.0 12.0 1.0 1 0 0 1 1 1 1 Ycf1 Raftlin PF15250.1 EDN05930.1 - 0.0061 15.1 10.6 0.0073 14.8 7.4 1.1 1 0 0 1 1 1 1 Raftlin DUF912 PF06024.7 EDN05930.1 - 0.0081 16.1 3.6 0.0081 16.1 2.5 2.2 1 1 1 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Neur_chan_memb PF02932.11 EDN05930.1 - 0.0094 15.8 10.9 0.012 15.5 7.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region FLO_LFY PF01698.11 EDN05930.1 - 0.011 14.6 17.8 0.014 14.2 12.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Band_3_cyto PF07565.8 EDN05930.1 - 0.011 15.2 6.5 0.012 15.1 4.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF1510 PF07423.6 EDN05930.1 - 0.012 15.0 33.9 0.015 14.6 23.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ABC2_membrane_3 PF12698.2 EDN05930.1 - 0.028 13.4 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein HCO3_cotransp PF00955.16 EDN05930.1 - 0.029 13.0 1.6 0.035 12.7 1.1 1.1 1 0 0 1 1 1 0 HCO3- transporter family SAPS PF04499.10 EDN05930.1 - 0.031 12.9 11.2 0.037 12.6 7.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ni_hydr_CYTB PF01292.15 EDN05930.1 - 0.041 13.2 0.0 0.061 12.7 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 GAGA_bind PF06217.7 EDN05930.1 - 0.043 13.7 28.6 0.067 13.1 19.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2370 PF10176.4 EDN05930.1 - 0.044 13.1 0.9 0.057 12.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) NARP1 PF12569.3 EDN05930.1 - 0.048 12.4 33.6 0.075 11.7 23.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 LicD PF04991.8 EDN05930.1 - 0.049 13.7 17.2 0.058 13.4 11.9 1.2 1 0 0 1 1 1 0 LicD family DUF4220 PF13968.1 EDN05930.1 - 0.05 12.6 6.2 0.055 12.5 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) CDC45 PF02724.9 EDN05930.1 - 0.057 11.4 22.6 0.067 11.2 15.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Herpes_UL95 PF03038.9 EDN05930.1 - 0.059 12.2 9.0 0.078 11.8 6.2 1.1 1 0 0 1 1 1 0 UL95 family DUF2427 PF10348.4 EDN05930.1 - 0.059 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Herpes_env PF01673.13 EDN05930.1 - 0.063 11.8 7.0 0.073 11.6 4.8 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DHHW PF14286.1 EDN05930.1 - 0.07 12.4 9.7 0.087 12.1 6.7 1.1 1 0 0 1 1 1 0 DHHW protein RP-C_C PF11800.3 EDN05930.1 - 0.07 12.8 8.7 0.096 12.3 6.0 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region SET PF00856.23 EDN05930.1 - 0.091 13.0 4.8 0.11 12.8 3.3 1.2 1 0 0 1 1 1 0 SET domain OPT PF03169.10 EDN05930.1 - 0.096 11.1 0.6 0.13 10.6 0.4 1.4 1 1 0 1 1 1 0 OPT oligopeptide transporter protein RPOL_N PF14700.1 EDN05930.1 - 0.097 11.9 13.7 0.11 11.7 9.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal BTV_NS2 PF04514.7 EDN05930.1 - 0.12 11.1 20.8 0.15 10.8 14.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF262 PF03235.9 EDN05930.1 - 0.14 12.0 14.1 0.17 11.8 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 DUF1632 PF07857.7 EDN05930.1 - 0.15 11.3 2.4 0.2 10.9 1.6 1.3 1 0 0 1 1 1 0 CEO family (DUF1632) LMBR1 PF04791.11 EDN05930.1 - 0.15 10.5 9.4 0.19 10.2 6.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SprA-related PF12118.3 EDN05930.1 - 0.17 11.1 21.3 0.2 10.9 14.8 1.1 1 0 0 1 1 1 0 SprA-related family YL1 PF05764.8 EDN05930.1 - 0.18 11.3 44.6 0.24 10.9 30.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein NPR3 PF03666.8 EDN05930.1 - 0.19 10.2 24.7 0.24 9.8 17.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cytochrom_B_N PF00033.14 EDN05930.1 - 0.19 11.0 2.2 0.79 9.0 1.5 1.9 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF913 PF06025.7 EDN05930.1 - 0.19 10.4 6.5 0.25 10.0 4.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.12 EDN05930.1 - 0.23 10.2 7.4 0.27 9.9 5.1 1.1 1 0 0 1 1 1 0 Presenilin Vma12 PF11712.3 EDN05930.1 - 0.24 11.1 8.0 0.34 10.6 5.6 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase SOBP PF15279.1 EDN05930.1 - 0.25 11.6 10.8 0.29 11.4 7.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein ATP11 PF06644.6 EDN05930.1 - 0.3 10.5 20.7 0.36 10.2 14.4 1.1 1 0 0 1 1 1 0 ATP11 protein Dsh_C PF12316.3 EDN05930.1 - 0.31 11.1 1.7 0.4 10.7 1.2 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Mem_trans PF03547.13 EDN05930.1 - 0.37 9.0 7.6 0.43 8.8 5.3 1.1 1 0 0 1 1 1 0 Membrane transport protein Vfa1 PF08432.5 EDN05930.1 - 0.38 10.7 41.0 0.57 10.1 28.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tyrosinase PF00264.15 EDN05930.1 - 0.49 10.5 2.9 0.59 10.2 2.0 1.3 1 0 0 1 1 1 0 Common central domain of tyrosinase RICTOR_N PF14664.1 EDN05930.1 - 0.54 8.7 3.1 0.83 8.1 2.2 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Tfb4 PF03850.9 EDN05930.1 - 0.58 9.3 5.1 0.75 8.9 3.6 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 FAM91_C PF14648.1 EDN05930.1 - 0.74 8.5 5.7 0.8 8.4 4.0 1.1 1 0 0 1 1 1 0 FAM91 C-terminus DUF3807 PF12720.2 EDN05930.1 - 0.82 9.8 29.9 1.2 9.2 20.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Apt1 PF10351.4 EDN05930.1 - 0.84 8.4 21.0 1 8.1 14.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2828 PF11443.3 EDN05930.1 - 0.92 7.6 17.3 1.3 7.1 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Serinc PF03348.10 EDN05930.1 - 1.1 7.9 12.7 1.6 7.3 8.8 1.4 1 1 0 1 1 1 0 Serine incorporator (Serinc) Scs3p PF10261.4 EDN05930.1 - 1.2 8.1 3.7 4.7 6.1 2.6 1.9 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2126 PF09899.4 EDN05930.1 - 1.2 7.0 7.2 1.6 6.6 5.0 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Mitofilin PF09731.4 EDN05930.1 - 1.4 7.5 25.9 1.7 7.2 17.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Apis_Csd PF11671.3 EDN05930.1 - 1.4 8.7 14.5 2 8.2 10.1 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein Cellulose_synt PF03552.9 EDN05930.1 - 1.5 7.0 12.1 1.8 6.7 8.4 1.1 1 0 0 1 1 1 0 Cellulose synthase Rtf2 PF04641.7 EDN05930.1 - 1.5 7.9 41.3 2.1 7.4 28.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger AAA_11 PF13086.1 EDN05930.1 - 1.6 8.2 18.7 2.2 7.7 13.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpb1_5 PF04998.12 EDN05930.1 - 1.8 7.7 18.4 2.1 7.5 12.8 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DDHD PF02862.12 EDN05930.1 - 1.8 8.3 19.5 3 7.5 13.5 1.4 1 0 0 1 1 1 0 DDHD domain DUF106 PF01956.11 EDN05930.1 - 2.1 7.8 14.7 3.5 7.1 10.2 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 Ndc1_Nup PF09531.5 EDN05930.1 - 2.3 6.5 10.0 2.6 6.3 6.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup YjgP_YjgQ PF03739.9 EDN05930.1 - 3.9 6.1 5.1 5 5.7 3.5 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family FliP PF00813.15 EDN05930.1 - 4.1 7.0 6.0 9.8 5.8 4.3 1.6 1 1 1 2 2 2 0 FliP family DUF4199 PF13858.1 EDN05930.1 - 5.3 6.9 7.2 21 5.0 5.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) DUF4407 PF14362.1 EDN05930.1 - 7.5 5.4 14.6 11 4.9 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Otopetrin PF03189.8 EDN05930.1 - 7.9 5.3 7.0 11 4.8 4.8 1.3 1 0 0 1 1 1 0 Otopetrin PIG-U PF06728.8 EDN05930.1 - 9.3 4.9 6.9 35 3.1 4.8 1.9 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U Myb_DNA-binding PF00249.26 EDN05931.1 - 1.9e-12 47.0 2.8 5e-09 36.0 0.1 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN05931.1 - 1.6e-08 34.5 0.7 1.2e-05 25.3 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Pkinase PF00069.20 EDN05932.1 - 2.1e-09 36.9 0.0 3.7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN05932.1 - 1.4e-07 31.4 0.2 2e-06 27.7 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EDN05932.1 - 0.00016 20.7 0.2 0.00035 19.6 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family HSDR_N_2 PF13588.1 EDN05932.1 - 0.0037 17.0 0.0 0.59 9.9 0.0 2.4 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) Pkinase_Tyr PF07714.12 EDN05932.1 - 0.0049 15.9 0.0 0.008 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EDN05932.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L38e PF01781.13 EDN05932.1 - 0.091 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L38e protein family EcKinase PF02958.15 EDN05932.1 - 0.18 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.17 EDN05933.1 - 0.018 14.4 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EDN05933.1 - 0.019 14.5 0.1 0.056 13.0 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.18 EDN05933.1 - 0.042 13.5 0.2 0.042 13.5 0.2 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family MAP7 PF05672.6 EDN05933.1 - 1.2 8.5 38.4 2.4 7.4 26.6 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family BCS1_N PF08740.6 EDN05935.1 - 2.5e-40 138.1 0.1 3.8e-40 137.4 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN05935.1 - 5.1e-20 72.0 0.0 2.8e-19 69.5 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN05935.1 - 0.0002 21.4 0.0 0.0008 19.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EDN05935.1 - 0.0045 17.7 0.1 0.029 15.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN05935.1 - 0.0094 15.3 0.0 0.022 14.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDN05935.1 - 0.016 15.0 0.0 0.46 10.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EDN05935.1 - 0.043 13.5 0.1 0.14 11.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EDN05935.1 - 0.056 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 EDN05935.1 - 0.063 13.4 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EDN05935.1 - 0.078 11.8 0.0 0.54 9.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 EDN05935.1 - 0.079 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 EDN05935.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF3435 PF11917.3 EDN05938.1 - 4.9e-164 546.0 0.2 6.3e-164 545.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DDE_Tnp_ISL3 PF01610.12 EDN05938.1 - 0.0019 17.8 1.3 0.0051 16.4 0.3 2.0 2 0 0 2 2 2 1 Transposase Phage_integrase PF00589.17 EDN05938.1 - 0.066 12.8 0.3 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Phage integrase family Zn-ribbon_8 PF09723.5 EDN05938.1 - 0.12 12.3 0.9 0.26 11.2 0.6 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Toxin_20 PF08089.6 EDN05938.1 - 4.4 7.2 7.2 0.13 12.1 0.5 1.7 2 0 0 2 2 2 0 Huwentoxin-II family AAA PF00004.24 EDN05939.1 - 3.1e-07 30.6 0.0 4.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NAD_kinase PF01513.16 EDN05942.1 - 1.2e-60 204.7 0.0 1.5e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase TRAPP PF04051.11 EDN05943.1 - 3.3e-34 117.5 0.0 4.3e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Prp19_bind PF06991.6 EDN05944.1 - 5.9e-29 101.2 21.8 5.9e-29 101.2 15.1 2.3 2 0 0 2 2 2 1 Splicing factor, Prp19-binding domain HNH_2 PF13391.1 EDN05945.1 - 5.8e-09 35.5 1.2 2.2e-08 33.7 0.0 2.6 4 0 0 4 4 4 1 HNH endonuclease Glyco_hydro_16 PF00722.16 EDN05946.1 - 1.6e-43 148.1 3.1 2.6e-43 147.4 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1191 PF06697.7 EDN05946.1 - 0.0058 15.4 0.0 0.0084 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Amidase_2 PF01510.20 EDN05947.1 - 1.2e-11 44.8 0.7 1.7e-11 44.2 0.5 1.2 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Rep_fac-A_3 PF08661.6 EDN05948.1 - 9.6e-24 83.3 0.0 1.1e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1 PF12658.2 EDN05948.1 - 0.017 14.8 0.1 0.22 11.2 0.1 2.0 1 1 0 1 1 1 0 Telomere capping, CST complex subunit SepZ PF06066.6 EDN05948.1 - 0.05 13.6 0.2 0.076 13.0 0.2 1.3 1 0 0 1 1 1 0 SepZ GATA PF00320.22 EDN05949.1 - 4.3e-06 25.9 4.8 0.00021 20.5 0.6 2.7 2 0 0 2 2 2 2 GATA zinc finger PA_decarbox PF05870.6 EDN05949.1 - 0.24 10.8 0.0 0.41 10.0 0.0 1.3 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) LSM PF01423.17 EDN05950.1 - 3.2e-18 65.0 0.1 4.2e-18 64.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain Baculo_44 PF04631.7 EDN05950.1 - 0.079 11.5 0.0 0.088 11.4 0.0 1.0 1 0 0 1 1 1 0 Baculovirus hypothetical protein Dak1 PF02733.12 EDN05952.1 - 1.2e-64 217.9 0.9 1.9e-64 217.2 0.7 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EDN05952.1 - 5.9e-43 146.5 0.1 9.7e-43 145.8 0.1 1.4 1 0 0 1 1 1 1 DAK2 domain DUF3414 PF11894.3 EDN05953.1 - 0 1170.0 15.0 0 1048.8 8.1 2.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3414) Cullin PF00888.17 EDN05953.1 - 2.4e-104 350.0 2.5 7e-104 348.4 1.7 1.7 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EDN05953.1 - 2.1e-23 81.8 0.7 5.2e-23 80.6 0.5 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain PI3_PI4_kinase PF00454.22 EDN05954.1 - 1.3e-46 158.9 0.0 2.4e-46 158.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EDN05954.1 - 5.6e-09 35.2 2.1 1.3e-08 34.0 0.1 2.5 3 0 0 3 3 3 1 FATC domain TPR_11 PF13414.1 EDN05954.1 - 0.0034 16.9 0.1 0.0088 15.6 0.1 1.7 1 0 0 1 1 1 1 TPR repeat zf-C3HC4_2 PF13923.1 EDN05955.1 - 2.1e-09 37.2 7.7 3.9e-09 36.3 5.3 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN05955.1 - 1.9e-08 33.8 8.4 2.8e-08 33.2 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN05955.1 - 9.2e-08 31.7 10.1 1.4e-07 31.1 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDN05955.1 - 1.4e-07 31.0 7.1 8.2e-07 28.5 5.3 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN05955.1 - 5.4e-06 26.0 10.2 9.4e-06 25.2 7.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EDN05955.1 - 2.9e-05 23.8 4.6 2.9e-05 23.8 3.2 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EDN05955.1 - 0.00036 20.1 7.3 0.0019 17.8 2.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 EDN05955.1 - 0.047 13.2 3.4 0.089 12.3 2.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-4CXXC_R1 PF10497.4 EDN05955.1 - 0.17 12.0 7.0 0.34 11.0 0.3 2.3 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_4 PF14570.1 EDN05955.1 - 0.37 10.3 8.0 1.2 8.7 5.6 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 EDN05955.1 - 0.68 9.6 4.3 1.3 8.7 3.0 1.5 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.2 EDN05955.1 - 0.86 9.7 6.2 3 7.9 4.3 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-met2 PF12907.2 EDN05955.1 - 1.8 8.5 6.6 12 5.9 1.3 2.5 2 0 0 2 2 2 0 Zinc-binding zf-Apc11 PF12861.2 EDN05955.1 - 2.5 7.9 7.9 14 5.5 5.5 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 EDN05955.1 - 3 7.3 5.3 4.4 6.8 0.3 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_6 PF14835.1 EDN05955.1 - 4.6 7.0 8.9 11 5.8 4.1 2.7 2 1 0 2 2 2 0 zf-RING of BARD1-type protein DNA_pol_A PF00476.15 EDN05956.1 - 1.7e-100 336.3 0.0 2.4e-100 335.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EDN05956.1 - 0.054 12.9 0.1 1.2 8.6 0.0 2.5 1 1 0 1 1 1 0 3'-5' exonuclease CorA PF01544.13 EDN05957.1 - 4.3e-17 62.0 7.2 1.4e-10 40.7 0.0 3.4 4 0 0 4 4 4 3 CorA-like Mg2+ transporter protein SQS_PSY PF00494.14 EDN05958.1 - 6.3e-44 150.2 0.0 9e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.18 EDN05959.1 - 6.9e-69 231.9 0.0 9.7e-69 231.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EDN05959.1 - 4.5e-16 58.7 0.0 9.1e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-C3HC4_2 PF13923.1 EDN05959.1 - 5.5e-07 29.4 8.4 1e-06 28.6 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 EDN05959.1 - 2.3e-06 27.3 0.0 7.4e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EDN05959.1 - 0.0002 20.9 7.6 0.0004 19.9 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN05959.1 - 0.00026 20.7 7.9 0.00052 19.7 5.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDN05959.1 - 0.00029 20.4 6.7 0.00055 19.5 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN05959.1 - 0.0033 17.1 6.9 0.0066 16.1 4.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain PLU-1 PF08429.6 EDN05959.1 - 0.0085 15.0 0.4 0.015 14.2 0.3 1.3 1 0 0 1 1 1 1 PLU-1-like protein zf-C3HC4_4 PF15227.1 EDN05959.1 - 0.025 14.4 7.0 0.048 13.5 4.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1574 PF07611.6 EDN05959.1 - 0.22 10.3 0.0 0.39 9.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) zf-RING_UBOX PF13445.1 EDN05959.1 - 0.46 10.2 5.5 1.1 9.0 3.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger GTP_EFTU PF00009.22 EDN05960.1 - 4.3e-22 78.4 0.0 1.5e-21 76.6 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDN05960.1 - 2.1e-15 56.6 0.1 5.2e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDN05960.1 - 1.2e-09 38.1 2.1 1.3e-08 34.7 0.8 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EDN05960.1 - 0.00048 19.6 0.3 0.47 9.9 0.1 3.4 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EDN05960.1 - 0.0029 18.0 0.1 0.045 14.2 0.1 2.9 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EDN05960.1 - 0.0065 16.4 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EDN05960.1 - 0.048 13.3 0.2 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EDN05960.1 - 0.1 12.3 0.7 0.26 11.0 0.1 1.9 2 0 0 2 2 2 0 Dynamin family GTP_EFTU_D4 PF14578.1 EDN05960.1 - 0.9 9.2 3.9 0.7 9.5 0.8 2.3 2 1 0 2 2 2 0 Elongation factor Tu domain 4 LSM PF01423.17 EDN05961.1 - 1.2e-17 63.2 0.3 1.6e-17 62.8 0.2 1.2 1 0 0 1 1 1 1 LSM domain ATP13 PF12921.2 EDN05962.1 - 8.5e-36 122.0 0.0 1.3e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.1 EDN05962.1 - 0.00025 20.9 0.0 0.0029 17.5 0.0 2.6 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.1 EDN05962.1 - 0.025 14.8 0.0 20 5.7 0.0 4.1 4 0 0 4 4 4 0 Pentatricopeptide repeat domain DUF1357 PF07094.6 EDN05962.1 - 0.061 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) PIG-L PF02585.12 EDN05963.1 - 1.5e-27 96.5 0.0 2.1e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase LDB19 PF13002.2 EDN05964.1 - 1.2e-64 217.3 0.0 1.9e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EDN05964.1 - 0.00021 21.1 0.0 0.00055 19.7 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF4606 PF15379.1 EDN05964.1 - 0.015 15.3 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) DUF2788 PF10981.3 EDN05965.1 - 0.079 12.7 0.3 0.25 11.1 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2788) MFS_1 PF07690.11 EDN05966.1 - 1.3e-25 89.9 24.1 1.3e-25 89.9 16.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.17 EDN05967.1 - 4.9e-22 78.0 0.0 4.9e-16 58.3 0.0 3.0 1 1 2 3 3 3 3 Cytochrome P450 TPP_enzyme_N PF02776.13 EDN05968.1 - 1.3e-34 119.1 0.0 3.1e-34 117.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDN05968.1 - 9.6e-19 67.5 0.0 2.6e-18 66.0 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EDN05968.1 - 7.1e-15 54.9 0.0 1.9e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EDN05968.1 - 0.023 13.4 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EDN05968.1 - 0.041 12.8 0.0 0.075 11.9 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Paramyx_P_V_C PF03210.8 EDN05970.1 - 0.089 12.6 0.7 0.095 12.5 0.5 1.1 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Exo_endo_phos_2 PF14529.1 EDN05971.1 - 0.00051 19.6 0.0 0.00099 18.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN05972.1 - 1.2e-14 54.7 0.0 2e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN05972.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like DIOX_N PF14226.1 EDN05973.1 - 3.3e-26 92.1 0.0 5.3e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EDN05973.1 - 4.2e-17 62.2 0.0 7.8e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DnaJ PF00226.26 EDN05974.1 - 5.8e-20 70.8 0.6 1.4e-19 69.5 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 EDN05974.1 - 0.12 12.0 0.3 0.43 10.2 0.2 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GCV_T_C PF08669.6 EDN05975.1 - 6.3e-05 22.9 0.0 8.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Big_4 PF07532.6 EDN05975.1 - 0.0071 15.8 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 4) phiKZ_IP PF12699.2 EDN05975.1 - 0.12 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins HTH_Tnp_Tc5 PF03221.11 EDN05976.1 - 0.0034 17.1 0.1 0.017 14.9 0.0 2.3 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_8 PF02954.14 EDN05976.1 - 0.02 14.4 2.0 0.28 10.7 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family HTH_psq PF05225.11 EDN05976.1 - 0.021 14.3 0.4 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_Tnp_IS630 PF01710.11 EDN05976.1 - 0.046 13.3 0.1 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Transposase Imm8 PF15560.1 EDN05976.1 - 0.12 12.0 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 8 DUF4112 PF13430.1 EDN05977.1 - 1.8e-21 76.0 0.3 2.4e-21 75.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF1405 PF07187.6 EDN05977.1 - 0.029 14.0 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1405) DUF2392 PF10288.4 EDN05978.1 - 1.6e-28 99.1 0.0 2.8e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Lung_7-TM_R PF06814.8 EDN05979.1 - 3.2e-37 128.0 21.1 4.2e-23 81.7 4.4 3.0 1 1 1 2 2 2 2 Lung seven transmembrane receptor DUF1308 PF07000.6 EDN05980.1 - 1.7e-41 142.0 0.0 1.9e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) WD40 PF00400.27 EDN05981.1 - 4.1e-14 51.8 8.9 6.5e-08 32.1 0.2 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF3312 PF11768.3 EDN05981.1 - 0.017 13.3 0.0 0.025 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF4263 PF14082.1 EDN05981.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) DUF4613 PF15390.1 EDN05981.1 - 0.058 11.5 0.0 0.09 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Coatomer_WDAD PF04053.9 EDN05981.1 - 0.15 10.8 0.0 0.26 10.0 0.0 1.4 1 1 0 1 1 1 0 Coatomer WD associated region Mito_carr PF00153.22 EDN05982.1 - 3.9e-36 122.6 1.5 8.3e-15 54.2 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Retrotrans_gag PF03732.12 EDN05983.1 - 2.3 8.3 16.2 1.4 9.0 1.9 3.8 2 1 2 4 4 4 0 Retrotransposon gag protein IncA PF04156.9 EDN05983.1 - 2.7 7.5 10.0 6.8 6.2 1.3 2.3 2 0 0 2 2 2 0 IncA protein FlxA PF14282.1 EDN05983.1 - 3.3 7.7 12.5 0.38 10.7 1.0 2.6 3 0 0 3 3 3 0 FlxA-like protein FUSC PF04632.7 EDN05983.1 - 6.4 5.0 5.4 16 3.7 1.3 2.3 2 1 0 2 2 2 0 Fusaric acid resistance protein family Angiomotin_C PF12240.3 EDN05983.1 - 8.7 5.7 11.4 2.5 7.5 0.4 2.2 2 0 0 2 2 2 0 Angiomotin C terminal UBN2 PF14223.1 EDN05984.1 - 0.0074 16.0 1.3 0.016 14.9 0.2 2.1 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Apelin PF15360.1 EDN05984.1 - 0.052 13.7 4.5 4.1 7.6 0.8 2.8 2 0 0 2 2 2 0 APJ endogenous ligand SCHIP-1 PF10148.4 EDN05984.1 - 0.76 9.1 6.0 0.24 10.7 2.0 1.6 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 DIOX_N PF14226.1 EDN05986.1 - 4.3e-18 65.9 0.1 6.8e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EDN05986.1 - 1.3e-11 44.6 0.0 0.00013 22.1 0.0 2.9 3 0 0 3 3 3 2 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.3 EDN05987.1 - 9.8e-79 263.7 0.0 2.6e-78 262.3 0.0 1.7 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EDN05987.1 - 2.6e-32 111.0 0.0 6.2e-32 109.7 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EDN05987.1 - 3e-12 46.4 0.0 6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EDN05987.1 - 0.00017 21.7 0.0 0.00038 20.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Thioredoxin PF00085.15 EDN05988.1 - 1.6e-59 198.0 0.0 1e-29 102.2 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EDN05988.1 - 6.6e-25 87.5 0.1 1.3e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EDN05988.1 - 2.1e-15 56.8 0.0 3.1e-07 30.5 0.0 3.3 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDN05988.1 - 2.5e-11 43.5 0.0 0.0014 18.6 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EDN05988.1 - 3.4e-11 43.0 0.0 0.00015 21.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EDN05988.1 - 2.4e-06 27.1 0.0 0.015 14.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EDN05988.1 - 4.7e-06 26.5 0.2 0.00064 19.5 0.1 2.8 2 1 1 3 3 3 1 Thioredoxin-like domain ERp29_N PF07912.8 EDN05988.1 - 6.1e-06 26.1 0.0 0.0017 18.2 0.0 2.6 2 1 0 2 2 2 1 ERp29, N-terminal domain AhpC-TSA PF00578.16 EDN05988.1 - 1.6e-05 24.5 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EDN05988.1 - 0.0001 21.8 0.1 0.2 11.2 0.0 2.5 2 1 0 2 2 2 2 Redoxin Thioredoxin_3 PF13192.1 EDN05988.1 - 0.00014 21.5 0.0 0.052 13.3 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain Glutaredoxin PF00462.19 EDN05988.1 - 0.0011 18.9 0.0 1.6 8.8 0.0 2.7 2 0 0 2 2 2 2 Glutaredoxin TraF PF13728.1 EDN05988.1 - 0.002 17.6 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 EDN05988.1 - 0.013 15.5 0.2 7.1 6.6 0.0 3.5 3 2 2 5 5 5 0 Thioredoxin DUF383 PF04063.9 EDN05988.1 - 0.04 13.4 0.0 0.28 10.6 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF383) DUF836 PF05768.9 EDN05988.1 - 0.16 12.2 0.0 6.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) MFS_1 PF07690.11 EDN05989.1 - 1.7e-16 59.8 69.6 1.1e-08 34.1 5.9 2.6 2 1 1 3 3 3 3 Major Facilitator Superfamily Ebp2 PF05890.7 EDN05990.1 - 5.6e-52 176.7 26.8 6.3e-52 176.5 18.5 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DUF106 PF01956.11 EDN05990.1 - 1.8 8.1 3.6 1.8 8.1 2.5 1.3 1 1 0 1 1 1 0 Integral membrane protein DUF106 SlyX PF04102.7 EDN05991.1 - 0.1 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 SlyX DNMT1-RFD PF12047.3 EDN05992.1 - 0.03 13.9 0.0 0.084 12.5 0.0 1.7 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain TruB_N PF01509.13 EDN05993.1 - 3.5e-44 150.5 0.0 1.1e-43 148.9 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) OHCU_decarbox PF09349.5 EDN05996.1 - 1.2e-52 178.4 0.4 1.5e-52 178.0 0.3 1.1 1 0 0 1 1 1 1 OHCU decarboxylase DUF4404 PF14357.1 EDN05996.1 - 3.4 8.1 7.4 1.2 9.6 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) PhoD PF09423.5 EDN05998.1 - 3.8e-151 503.7 5.8 4.4e-151 503.4 4.0 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase WD40 PF00400.27 EDN05999.1 - 2.6e-30 103.1 11.6 7.3e-08 32.0 0.0 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat SRP9-21 PF05486.7 EDN06000.1 - 7e-31 105.8 4.5 1.2e-30 105.0 3.2 1.4 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.16 EDN06001.1 - 1.5e-71 240.6 1.2 1.9e-71 240.3 0.8 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain RNase_H PF00075.19 EDN06003.1 - 2.9e-15 56.7 0.0 4.5e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN06003.1 - 0.069 12.9 0.1 0.26 11.0 0.1 2.0 1 1 0 1 1 1 0 Reverse transcriptase-like Pkinase PF00069.20 EDN06004.1 - 8.7e-09 34.9 0.1 1.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN06004.1 - 0.021 14.5 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN06004.1 - 0.036 13.1 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase WD40 PF00400.27 EDN06005.1 - 1.1e-36 123.4 21.8 1.3e-07 31.2 0.0 6.1 5 1 1 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 EDN06005.1 - 0.00076 19.2 0.0 0.053 13.2 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A 2-Hacid_dh_C PF02826.14 EDN06006.1 - 6.8e-51 171.9 0.0 9.2e-51 171.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDN06006.1 - 1.6e-14 53.4 0.0 1.9e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EDN06006.1 - 7.7e-07 29.0 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EDN06006.1 - 0.02 15.3 0.0 0.042 14.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Phosducin PF02114.11 EDN06007.1 - 1.4e-13 50.2 0.0 3e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 Phosducin Clathrin_lg_ch PF01086.12 EDN06007.1 - 0.044 13.7 3.8 0.061 13.2 2.6 1.3 1 1 0 1 1 1 0 Clathrin light chain Ran_BP1 PF00638.13 EDN06009.1 - 1.9e-50 170.0 1.9 2.8e-50 169.4 1.3 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EDN06009.1 - 4.2e-05 23.2 0.6 0.00032 20.3 0.4 2.0 1 1 0 1 1 1 1 WH1 domain RAI1 PF08652.6 EDN06009.1 - 0.14 11.9 0.6 0.65 9.8 0.1 2.1 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease Glyco_transf_15 PF01793.11 EDN06011.1 - 1e-133 445.4 3.7 1.3e-133 445.0 2.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PH PF00169.24 EDN06012.1 - 2.9e-27 94.9 1.0 5e-13 49.1 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_9 PF15410.1 EDN06012.1 - 2.6e-11 43.6 1.6 8.8e-06 25.8 0.0 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 EDN06012.1 - 8.3e-11 42.1 2.0 0.00032 20.9 0.5 3.5 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 EDN06012.1 - 0.00021 21.1 0.1 0.94 9.4 0.0 2.4 2 0 0 2 2 2 2 PH domain Mcp5_PH PF12814.2 EDN06012.1 - 0.038 13.9 0.1 0.72 9.7 0.0 2.2 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology DOT1 PF08123.8 EDN06013.1 - 6.2e-68 228.1 0.0 9.3e-68 227.5 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EDN06013.1 - 0.0029 17.6 0.0 0.0063 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ATG16 PF08614.6 EDN06014.1 - 1.4e-43 148.9 17.2 1.4e-43 148.9 11.9 1.4 2 0 0 2 2 1 1 Autophagy protein 16 (ATG16) DDE_3 PF13358.1 EDN06014.1 - 1.6e-07 31.1 1.5 3.6e-07 30.0 1.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease CCDC144C PF14915.1 EDN06014.1 - 0.0011 17.9 9.1 0.0021 17.0 6.3 1.4 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region ALIX_LYPXL_bnd PF13949.1 EDN06014.1 - 0.0039 16.2 9.5 1.1 8.2 6.6 2.4 2 0 0 2 2 2 2 ALIX V-shaped domain binding to HIV Drf_FH3 PF06367.11 EDN06014.1 - 0.058 12.7 3.9 0.091 12.1 2.7 1.2 1 0 0 1 1 1 0 Diaphanous FH3 Domain IncA PF04156.9 EDN06014.1 - 0.1 12.1 9.2 0.045 13.3 4.0 2.0 2 0 0 2 2 2 0 IncA protein Spc7 PF08317.6 EDN06014.1 - 0.12 11.0 10.6 1.2 7.7 5.5 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF4201 PF13870.1 EDN06014.1 - 0.14 11.6 12.5 0.29 10.5 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) ADK PF00406.17 EDN06014.1 - 0.14 12.0 1.6 5 6.9 0.3 2.2 1 1 1 2 2 2 0 Adenylate kinase TPR_MLP1_2 PF07926.7 EDN06014.1 - 0.17 11.6 18.6 3.8 7.2 1.2 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EDN06014.1 - 0.27 10.3 2.4 0.5 9.4 1.7 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Seryl_tRNA_N PF02403.17 EDN06014.1 - 1.1 9.3 11.9 0.36 10.8 5.0 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Snapin_Pallidin PF14712.1 EDN06014.1 - 1.9 8.8 10.6 5.9 7.2 2.4 2.9 2 1 2 4 4 3 0 Snapin/Pallidin HlyD PF00529.15 EDN06014.1 - 1.9 7.6 11.8 9.6 5.4 8.2 2.1 1 1 0 1 1 1 0 HlyD family secretion protein APG6 PF04111.7 EDN06014.1 - 2.5 7.0 12.1 4.2 6.3 8.4 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 EDN06014.1 - 2.6 7.2 16.5 1.1 8.3 8.3 2.4 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 EDN06014.1 - 2.9 5.6 6.4 4.6 4.9 4.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup54 PF13874.1 EDN06014.1 - 3.8 7.1 12.4 0.6 9.7 0.8 2.7 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 GvpG PF05120.7 EDN06014.1 - 4.7 7.0 7.9 0.82 9.5 0.6 2.6 1 1 1 2 2 2 0 Gas vesicle protein G Ras PF00071.17 EDN06015.1 - 1.6e-42 144.6 0.1 2e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN06015.1 - 4.5e-10 40.0 0.0 7.1e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN06015.1 - 9e-07 28.2 0.0 1.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDN06015.1 - 5.7e-05 22.6 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDN06015.1 - 0.012 14.7 0.0 0.015 14.4 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EDN06015.1 - 0.065 12.7 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein UAA PF08449.6 EDN06016.1 - 0.35 9.7 6.9 0.39 9.6 4.8 1.0 1 0 0 1 1 1 0 UAA transporter family EamA PF00892.15 EDN06016.1 - 0.85 9.6 15.7 0.99 9.4 10.9 1.1 1 0 0 1 1 1 0 EamA-like transporter family TPT PF03151.11 EDN06016.1 - 4 7.0 10.9 5.3 6.6 7.6 1.1 1 0 0 1 1 1 0 Triose-phosphate Transporter family Gly_kinase PF02595.10 EDN06017.1 - 1.5e-115 385.9 5.0 1.8e-115 385.7 3.4 1.0 1 0 0 1 1 1 1 Glycerate kinase family MFS_1 PF07690.11 EDN06018.1 - 3e-17 62.3 31.7 2e-11 43.1 4.8 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN06018.1 - 5.3e-09 35.1 0.9 5.3e-09 35.1 0.6 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Spb1_C PF07780.7 EDN06019.1 - 2.6e-75 252.6 23.0 2.6e-75 252.6 16.0 2.6 2 2 0 2 2 2 1 Spb1 C-terminal domain FtsJ PF01728.14 EDN06019.1 - 1.2e-54 185.0 0.0 2.3e-54 184.1 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF713 PF05218.9 EDN06021.1 - 0.032 13.9 0.1 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Fungal_trans PF04082.13 EDN06022.1 - 0.00057 18.8 0.1 0.00071 18.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_4 PF12763.2 EDN06023.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DNA_ligase_A_M PF01068.16 EDN06024.1 - 6.3e-46 156.2 0.0 1.2e-45 155.3 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EDN06024.1 - 1.3e-38 132.5 0.0 2.3e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EDN06024.1 - 1.7e-16 60.4 0.0 2.2e-15 56.8 0.0 2.6 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EDN06024.1 - 5.6e-07 29.6 0.0 0.00021 21.3 0.0 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 EDN06024.1 - 0.0059 16.3 0.0 0.2 11.3 0.0 2.9 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain Prothymosin PF03247.9 EDN06025.1 - 4.9e-05 23.4 12.0 8.6e-05 22.6 8.3 1.3 1 0 0 1 1 1 1 Prothymosin/parathymosin family DUF2890 PF11081.3 EDN06025.1 - 0.042 13.9 5.0 0.074 13.1 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 EDN06025.1 - 0.049 11.6 8.4 0.067 11.2 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 EDN06025.1 - 0.19 9.9 2.0 0.26 9.5 1.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Pox_Ag35 PF03286.9 EDN06025.1 - 0.44 10.0 4.5 1.2 8.6 3.1 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 EDN06025.1 - 0.55 8.0 13.0 0.79 7.5 9.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EDN06025.1 - 1.1 8.5 12.6 1.5 7.9 8.7 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 EDN06025.1 - 1.1 7.8 20.3 2.2 6.9 14.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 EDN06025.1 - 2 6.1 4.4 3.1 5.5 3.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_3_Rpc31 PF11705.3 EDN06025.1 - 2.1 8.1 20.6 4.1 7.2 14.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NOA36 PF06524.7 EDN06025.1 - 2.5 7.3 10.2 3.8 6.6 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 EDN06025.1 - 2.5 6.4 13.1 3.8 5.8 9.1 1.2 1 0 0 1 1 1 0 Daxx Family RXT2_N PF08595.6 EDN06025.1 - 2.5 7.8 7.4 6.1 6.6 5.1 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal VID27 PF08553.5 EDN06025.1 - 4 5.5 8.7 5.3 5.1 6.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Zn_clus PF00172.13 EDN06026.1 - 2.9e-09 36.6 8.5 6.6e-09 35.5 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.24 EDN06026.1 - 0.015 15.0 3.9 0.025 14.2 2.7 1.4 1 0 0 1 1 1 0 PHD-finger Sigma54_DBD PF04552.8 EDN06026.1 - 0.046 13.2 0.1 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54, DNA binding domain Metallophos PF00149.23 EDN06028.1 - 9.5e-35 119.8 0.8 2.3e-29 102.2 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF4646 PF15496.1 EDN06030.1 - 1e-09 38.4 0.0 1.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) ALG3 PF05208.8 EDN06031.1 - 1.4e-84 284.4 11.9 1.9e-84 284.0 8.3 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.14 EDN06032.1 - 2e-16 59.1 0.0 3.1e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Pkinase PF00069.20 EDN06033.1 - 5.8e-62 209.1 0.0 9.8e-62 208.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06033.1 - 1.7e-36 125.6 0.0 2.9e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EDN06033.1 - 4.4e-28 96.8 9.1 8.5e-15 54.2 0.9 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EDN06033.1 - 9.1e-14 50.9 19.9 8.4e-12 44.6 6.7 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EDN06033.1 - 3e-13 50.0 4.0 9.5e-13 48.4 2.8 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EDN06033.1 - 0.076 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like FYVE_2 PF02318.11 EDN06033.1 - 0.13 12.1 3.6 0.36 10.7 2.5 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger DUF605 PF04652.11 EDN06033.1 - 0.92 8.8 24.1 0.99 8.7 12.6 2.3 2 0 0 2 2 2 0 Vta1 like TFCD_C PF12612.3 EDN06035.1 - 2.4e-46 157.6 0.2 8.8e-46 155.7 0.1 2.1 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EDN06035.1 - 4.4e-10 38.7 5.9 1.2 9.3 0.0 7.7 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.1 EDN06035.1 - 7.1e-07 29.4 0.3 0.65 10.3 0.0 5.7 5 2 0 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EDN06035.1 - 0.0026 18.0 0.0 8.4 6.8 0.0 3.7 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EDN06035.1 - 0.0055 17.1 7.3 29 5.3 0.0 6.8 7 1 0 7 7 7 1 HEAT-like repeat RRM_1 PF00076.17 EDN06036.1 - 1.4e-22 79.1 3.2 1.9e-11 43.4 0.1 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN06036.1 - 5.3e-17 61.4 0.0 1.3e-09 37.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN06036.1 - 2.3e-15 56.2 0.7 2.6e-06 27.3 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ATP-synt_D PF01813.12 EDN06037.1 - 1e-65 220.9 2.2 1.6e-65 220.3 1.5 1.2 1 0 0 1 1 1 1 ATP synthase subunit D RICH PF05062.7 EDN06037.1 - 0.16 12.0 4.3 0.31 11.2 0.8 2.3 2 0 0 2 2 2 0 RICH domain Prefoldin PF02996.12 EDN06037.1 - 0.45 10.1 4.9 0.76 9.4 0.1 3.1 2 1 2 4 4 4 0 Prefoldin subunit Nup54 PF13874.1 EDN06037.1 - 0.98 9.0 4.9 2.4 7.8 0.1 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Viral_P18 PF04521.8 EDN06037.1 - 2 7.8 5.4 11 5.4 0.1 2.4 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein SYCE1 PF15233.1 EDN06037.1 - 3 7.7 8.0 0.24 11.3 1.5 2.1 3 1 0 3 3 3 0 Synaptonemal complex central element protein 1 TPR_14 PF13428.1 EDN06038.1 - 7.4e-15 54.1 7.8 1.5 9.6 0.0 11.9 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDN06038.1 - 3.8e-11 42.7 0.1 0.23 11.4 0.0 7.5 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN06038.1 - 6.9e-09 35.9 0.5 0.12 12.6 0.0 6.9 7 2 1 9 9 8 1 Tetratricopeptide repeat Suf PF05843.9 EDN06038.1 - 1.3e-08 34.9 13.9 0.13 11.9 0.0 6.3 4 1 2 6 6 6 3 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EDN06038.1 - 3.6e-07 29.7 8.3 2.8 7.6 0.0 7.8 8 2 1 9 9 8 1 TPR repeat TPR_2 PF07719.12 EDN06038.1 - 3.2e-06 26.6 10.7 3.6 7.7 0.0 7.9 8 0 0 8 8 7 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EDN06038.1 - 5.2e-05 23.0 9.7 0.87 9.3 0.1 6.6 6 1 0 7 7 7 1 Mad3/BUB1 homology region 1 TPR_8 PF13181.1 EDN06038.1 - 0.00022 20.7 4.8 0.97 9.3 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat HAT PF02184.11 EDN06038.1 - 0.00051 19.7 2.7 2.3 8.0 0.0 5.7 5 0 0 5 5 5 1 HAT (Half-A-TPR) repeat TPR_7 PF13176.1 EDN06038.1 - 0.0012 18.5 12.3 7 6.7 0.0 8.9 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDN06038.1 - 0.0052 16.8 5.4 0.57 10.5 0.0 6.5 10 0 0 10 10 7 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EDN06038.1 - 0.012 14.4 10.6 0.098 11.5 1.4 5.3 3 2 2 5 5 5 0 NRDE-2, necessary for RNA interference TPR_4 PF07721.9 EDN06038.1 - 0.043 14.2 7.3 5.7 7.6 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3563 PF12086.3 EDN06038.1 - 0.051 13.3 0.4 10 5.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3563) PPR PF01535.15 EDN06038.1 - 0.49 10.4 3.2 1.2e+02 3.0 0.0 5.0 5 0 0 5 5 4 0 PPR repeat Sec7 PF01369.15 EDN06040.1 - 1.9e-57 194.0 0.0 3e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EDN06040.1 - 1.1e-06 28.2 0.0 3.3e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal RhoGEF PF00621.15 EDN06041.1 - 1.1e-22 80.8 0.0 2.3e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 EDN06041.1 - 1.1e-08 34.8 0.0 2.1e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) ATP_bind_3 PF01171.15 EDN06043.1 - 4.9e-07 29.4 0.0 1.1e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 PP-loop family Mito_carr PF00153.22 EDN06044.1 - 4.9e-49 163.9 0.8 8.3e-21 73.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Cupin_5 PF06172.6 EDN06045.1 - 2e-20 73.1 0.0 4e-20 72.1 0.0 1.5 1 1 0 1 1 1 1 Cupin superfamily (DUF985) DUF3337 PF11816.3 EDN06046.1 - 4e-76 256.5 1.8 8.5e-72 242.3 3.5 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EDN06046.1 - 2.1e-24 84.4 20.3 1.2e-08 34.4 0.1 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Glyco_hydro_18 PF00704.23 EDN06047.1 - 6.9e-49 167.1 0.0 8.2e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.20 EDN06048.1 - 3.4e-56 190.2 0.2 1.9e-55 187.8 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06048.1 - 1.1e-19 70.5 0.0 2.2e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN06048.1 - 0.0077 15.9 0.1 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family BAF1_ABF1 PF04684.8 EDN06048.1 - 0.053 12.3 0.0 0.053 12.3 0.0 1.7 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Kinase-like PF14531.1 EDN06048.1 - 0.11 11.4 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ribosomal_L11_N PF03946.9 EDN06049.1 - 1.3e-26 91.8 0.2 1.6e-25 88.3 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EDN06049.1 - 4e-23 81.3 0.2 4e-23 81.3 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Svf1 PF08622.5 EDN06050.1 - 2.1e-129 431.1 0.0 2.7e-129 430.8 0.0 1.1 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 EDN06050.1 - 0.046 13.0 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Hydroxyneurosporene synthase (CrtC) TAF PF02969.12 EDN06051.1 - 0.012 15.5 0.3 0.022 14.7 0.0 1.6 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) YpjP PF14005.1 EDN06051.1 - 0.12 12.0 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 YpjP-like protein Acetyltransf_1 PF00583.19 EDN06053.1 - 9.2e-06 25.6 0.1 1.8e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EDN06053.1 - 0.0022 18.1 0.3 3.1 7.9 0.1 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EDN06053.1 - 0.041 13.6 0.4 0.08 12.6 0.3 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.1 EDN06053.1 - 0.058 13.5 0.1 0.52 10.5 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDN06053.1 - 0.1 12.4 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain HEAT PF02985.17 EDN06053.1 - 0.38 10.9 1.9 6.6 7.0 0.1 2.8 2 0 0 2 2 2 0 HEAT repeat CAF1-p150_C2 PF15539.1 EDN06053.1 - 1.7 7.6 5.5 8.8 5.3 0.1 2.2 2 0 0 2 2 2 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Dynein_heavy PF03028.10 EDN06054.1 - 5.5e-106 355.2 0.0 5.5e-106 355.2 0.0 1.6 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 EDN06054.1 - 9.5e-44 148.9 0.8 1.7e-43 148.0 0.1 1.9 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 EDN06054.1 - 1e-39 136.2 5.3 1.7e-39 135.5 3.7 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor 3-alpha PF03475.9 EDN06054.1 - 0.0026 17.4 0.1 0.0079 15.8 0.1 1.8 1 0 0 1 1 1 1 3-alpha domain BRE1 PF08647.6 EDN06054.1 - 0.004 17.1 1.2 0.004 17.1 0.8 3.5 2 1 0 2 2 2 1 BRE1 E3 ubiquitin ligase ERM PF00769.14 EDN06054.1 - 0.071 12.6 25.2 0.13 11.7 8.6 2.6 3 0 0 3 3 3 0 Ezrin/radixin/moesin family zf-C4H2 PF10146.4 EDN06054.1 - 0.075 13.0 0.0 0.075 13.0 0.0 2.9 3 0 0 3 3 3 0 Zinc finger-containing protein WXG100 PF06013.7 EDN06054.1 - 1.2 9.1 9.6 0.1 12.6 0.9 3.3 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DUF1664 PF07889.7 EDN06054.1 - 4.1 7.2 10.5 3 7.6 1.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DHC_N1 PF08385.7 EDN06055.1 - 1.8e-182 607.7 13.0 1.8e-182 607.7 9.0 3.5 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EDN06055.1 - 3.3e-131 437.5 9.1 1.1e-130 435.8 3.6 3.3 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EDN06055.1 - 2e-77 259.8 0.0 4.4e-77 258.7 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_5 PF07728.9 EDN06055.1 - 2.5e-23 82.3 0.0 1.5e-10 40.9 0.0 4.9 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EDN06055.1 - 5.9e-18 64.9 0.0 7.8e-17 61.2 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EDN06055.1 - 1.6e-10 41.2 0.2 0.0064 16.6 0.0 5.1 5 0 0 5 5 4 3 AAA domain AAA PF00004.24 EDN06055.1 - 2.1e-08 34.4 0.0 0.00029 21.0 0.0 3.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EDN06055.1 - 4.4e-06 26.6 0.9 0.47 10.3 0.0 4.1 4 0 0 4 4 3 2 AAA domain Zeta_toxin PF06414.7 EDN06055.1 - 8.2e-05 21.7 0.0 0.6 9.1 0.0 3.1 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 EDN06055.1 - 0.00037 20.4 0.0 0.12 12.3 0.0 4.3 4 0 0 4 4 3 1 AAA domain AAA_17 PF13207.1 EDN06055.1 - 0.00043 21.0 0.0 16 6.3 0.0 4.6 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EDN06055.1 - 0.00061 20.0 0.1 4 7.7 0.0 4.3 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.12 EDN06055.1 - 0.0022 17.4 0.1 0.22 10.9 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_19 PF13245.1 EDN06055.1 - 0.0026 17.4 0.5 0.56 9.9 0.0 3.6 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 EDN06055.1 - 0.0033 16.5 2.0 0.32 10.1 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EDN06055.1 - 0.0045 15.9 0.0 0.044 12.6 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_30 PF13604.1 EDN06055.1 - 0.0046 16.5 0.2 16 5.0 0.1 3.5 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 EDN06055.1 - 0.0066 15.9 0.0 1.6 8.3 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EDN06055.1 - 0.01 16.1 0.0 1.3 9.2 0.0 3.5 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 EDN06055.1 - 0.019 15.1 0.1 23 5.2 0.0 3.8 3 0 0 3 3 3 0 RNA helicase AAA_11 PF13086.1 EDN06055.1 - 0.02 14.4 1.9 2 7.9 0.0 3.7 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.13 EDN06055.1 - 0.024 14.1 0.5 14 5.1 0.0 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_25 PF13481.1 EDN06055.1 - 0.058 12.7 4.8 0.28 10.5 0.0 3.8 5 0 0 5 5 4 0 AAA domain DUF258 PF03193.11 EDN06055.1 - 0.12 11.5 0.0 6.7 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Ribonuclease_3 PF00636.21 EDN06056.1 - 7e-44 148.9 0.0 3.5e-21 75.7 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EDN06056.1 - 2.3e-27 95.4 0.0 1.4e-14 54.1 0.0 3.8 2 1 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EDN06056.1 - 2.9e-21 75.0 0.0 8.5e-20 70.3 0.0 2.7 2 0 0 2 2 2 1 Dicer dimerisation domain ResIII PF04851.10 EDN06056.1 - 0.00012 21.9 0.6 0.00028 20.7 0.2 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit dsrm PF00035.20 EDN06056.1 - 0.00071 20.1 0.2 0.053 14.1 0.1 2.7 2 0 0 2 2 2 1 Double-stranded RNA binding motif DEAD PF00270.24 EDN06056.1 - 0.00098 18.6 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TAP42 PF04177.7 EDN06057.1 - 2.3e-107 358.9 2.1 2.6e-107 358.7 1.5 1.0 1 0 0 1 1 1 1 TAP42-like family DUF4477 PF14780.1 EDN06057.1 - 0.11 11.8 0.5 0.19 11.1 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) Lipase_GDSL_2 PF13472.1 EDN06058.1 - 3.4e-06 27.2 0.0 0.011 15.8 0.0 2.3 1 1 1 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EDN06058.1 - 0.019 14.8 0.0 1.9 8.2 0.0 2.1 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase Porphobil_deam PF01379.15 EDN06059.1 - 1.1e-73 246.7 0.0 1.5e-73 246.2 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EDN06059.1 - 1.5e-17 63.4 0.3 3.1e-17 62.4 0.2 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Lon_C PF05362.8 EDN06060.1 - 2.1e-69 232.9 0.3 4.5e-69 231.8 0.2 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EDN06060.1 - 1.1e-24 87.0 0.0 5.5e-24 84.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 EDN06060.1 - 1.4e-23 83.7 0.6 2.8e-23 82.6 0.0 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 EDN06060.1 - 2.4e-08 33.4 0.0 9.9e-08 31.5 0.0 2.1 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EDN06060.1 - 5.1e-08 32.7 0.0 2.3e-07 30.6 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDN06060.1 - 2e-06 27.9 0.0 6.8e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EDN06060.1 - 8.8e-06 26.5 0.1 3.3e-05 24.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 EDN06060.1 - 9.1e-06 24.6 0.0 5.2e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_3 PF07726.6 EDN06060.1 - 6.6e-05 22.5 0.0 0.0002 20.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EDN06060.1 - 7.8e-05 22.3 0.1 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EDN06060.1 - 8.3e-05 22.0 0.0 0.00021 20.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EDN06060.1 - 0.00013 21.0 0.0 0.0015 17.6 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EDN06060.1 - 0.00042 20.2 0.0 0.0019 18.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EDN06060.1 - 0.00045 20.3 0.3 0.0037 17.3 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EDN06060.1 - 0.00058 19.7 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Birna_VP4 PF01768.11 EDN06060.1 - 0.00069 18.7 0.0 0.0016 17.5 0.0 1.6 1 0 0 1 1 1 1 Birnavirus VP4 protein AAA_14 PF13173.1 EDN06060.1 - 0.0016 18.3 0.0 0.0053 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDN06060.1 - 0.0023 17.0 0.0 0.005 15.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.1 EDN06060.1 - 0.0048 16.5 0.1 0.013 15.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EDN06060.1 - 0.0076 15.8 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDN06060.1 - 0.0089 15.4 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EDN06060.1 - 0.016 15.3 0.0 0.056 13.6 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EDN06060.1 - 0.017 14.2 0.1 0.046 12.8 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EDN06060.1 - 0.02 14.1 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EDN06060.1 - 0.024 14.3 0.0 0.077 12.6 0.0 1.9 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EDN06060.1 - 0.028 13.2 0.0 0.067 12.0 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 EDN06060.1 - 0.031 14.5 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EDN06060.1 - 0.032 14.5 0.1 0.032 14.5 0.0 3.1 1 1 1 2 2 1 0 AAA domain UPF0079 PF02367.12 EDN06060.1 - 0.047 13.3 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EDN06060.1 - 0.07 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_PrkA PF08298.6 EDN06060.1 - 0.076 11.6 0.1 0.5 9.0 0.0 2.0 2 0 0 2 2 2 0 PrkA AAA domain AAA_11 PF13086.1 EDN06060.1 - 0.081 12.4 4.7 0.12 11.9 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_10 PF12846.2 EDN06060.1 - 0.091 12.1 0.9 0.88 8.9 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 EDN06060.1 - 0.12 12.3 0.1 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EDN06060.1 - 0.12 12.1 1.1 0.67 9.6 0.0 2.8 3 0 0 3 3 3 0 NTPase ABC_tran PF00005.22 EDN06060.1 - 0.58 10.4 3.1 1.4 9.2 0.1 2.8 1 1 1 2 2 2 0 ABC transporter Ribosomal_L23 PF00276.15 EDN06061.1 - 3.2e-15 55.8 0.0 5.6e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 RIO1 PF01163.17 EDN06062.1 - 7.6e-33 113.4 0.1 2.5e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 RIO1 family APH PF01636.18 EDN06062.1 - 1.3e-07 31.5 0.1 0.00018 21.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EDN06062.1 - 3.4e-05 23.0 0.0 0.0018 17.3 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family COPI_C PF06957.6 EDN06062.1 - 0.39 9.2 4.9 0.5 8.8 3.4 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Daxx PF03344.10 EDN06062.1 - 1.9 6.8 7.4 8.8 4.6 6.0 1.4 2 0 0 2 2 2 0 Daxx Family NOA36 PF06524.7 EDN06062.1 - 6.4 5.9 6.2 8.6 5.5 4.3 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 EDN06062.1 - 9.8 6.4 10.6 19 5.5 7.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PC_rep PF01851.17 EDN06063.1 - 1.2e-15 56.7 19.8 4.1e-05 23.5 0.2 9.0 10 0 0 10 10 10 3 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EDN06063.1 - 5.4e-06 26.6 1.0 0.22 11.7 0.1 4.6 3 1 0 3 3 3 2 HEAT repeats RNase_P_p30 PF01876.11 EDN06063.1 - 0.016 14.4 0.1 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 RNase P subunit p30 DUF106 PF01956.11 EDN06063.1 - 0.086 12.3 0.1 5.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Integral membrane protein DUF106 TPR_5 PF12688.2 EDN06063.1 - 0.21 11.6 1.9 16 5.5 0.0 3.6 3 0 0 3 3 3 0 Tetratrico peptide repeat Pkinase PF00069.20 EDN06067.1 - 6.4e-10 38.6 0.0 1.2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN06067.1 - 0.017 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN06067.1 - 0.038 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase rve PF00665.21 EDN06068.1 - 4.3e-14 52.6 0.1 1.8e-13 50.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_2 PF07727.9 EDN06068.1 - 8.7e-12 44.5 0.0 1.6e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4219 PF13961.1 EDN06068.1 - 0.02 14.3 1.9 0.05 13.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) gag_pre-integrs PF13976.1 EDN06068.1 - 0.023 14.3 0.0 0.063 12.9 0.0 1.7 1 0 0 1 1 1 0 GAG-pre-integrase domain Kdo PF06293.9 EDN06069.1 - 6.8e-05 22.0 0.1 0.00017 20.6 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN06069.1 - 0.024 14.3 7.0 0.092 12.4 0.1 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN06069.1 - 0.038 13.5 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EDN06069.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Thioredoxin_9 PF14595.1 EDN06073.1 - 0.091 12.3 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin DSPc PF00782.15 EDN06074.1 - 0.0028 17.2 0.0 0.037 13.5 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain RTC4 PF14474.1 EDN06076.1 - 3.9e-30 104.3 0.0 6.4e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain Myb_DNA-bind_6 PF13921.1 EDN06076.1 - 9.3e-06 25.6 2.7 9.3e-06 25.6 1.9 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN06076.1 - 0.00049 20.0 2.1 0.0013 18.7 1.5 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain RHSP PF07999.6 EDN06076.1 - 0.17 10.4 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Retrotransposon hot spot protein DB PF01682.14 EDN06077.1 - 0.044 13.8 0.1 10 6.1 0.0 2.3 2 0 0 2 2 2 0 DB module ClpB_D2-small PF10431.4 EDN06077.1 - 0.083 12.7 0.2 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein Toxin_2 PF00451.14 EDN06077.1 - 1.2 9.3 2.9 9.2 6.4 0.2 2.2 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 Zn_clus PF00172.13 EDN06081.1 - 6.9e-05 22.6 2.0 0.00021 21.1 1.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2783 PF10932.3 EDN06083.1 - 0.064 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) bZIP_1 PF00170.16 EDN06084.1 - 0.014 15.3 0.4 0.027 14.4 0.3 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF281 PF03436.8 EDN06085.1 - 0.013 15.5 0.2 0.016 15.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF281) Lac_bphage_repr PF06543.7 EDN06088.1 - 0.055 13.0 1.7 0.15 11.6 1.2 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor DUF4593 PF15263.1 EDN06088.1 - 0.75 9.6 5.6 1.4 8.8 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4593) RVT_1 PF00078.22 EDN06090.1 - 2.9e-29 101.9 0.0 5.6e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN06090.1 - 1.9e-18 66.2 0.1 7.5e-18 64.2 0.1 2.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN06090.1 - 6.7e-18 65.3 0.0 1.9e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EDN06090.1 - 2.9e-07 30.7 0.2 7.8e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_3 PF13456.1 EDN06090.1 - 7.8e-05 22.3 0.0 0.00022 20.9 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like zf-CCHC PF00098.18 EDN06090.1 - 0.016 15.0 4.9 0.048 13.6 3.4 1.8 1 0 0 1 1 1 0 Zinc knuckle PuR_N PF09182.5 EDN06090.1 - 0.017 14.6 0.0 0.049 13.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal zf-C3HC4 PF00097.20 EDN06091.1 - 8.1e-05 22.2 3.7 0.00025 20.6 2.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN06091.1 - 0.0024 17.4 8.9 0.0046 16.6 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TMF_TATA_bd PF12325.3 EDN06091.1 - 0.0047 16.6 2.5 0.0069 16.1 1.7 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DegS PF05384.6 EDN06091.1 - 0.0053 15.9 4.2 0.0075 15.4 2.9 1.2 1 0 0 1 1 1 1 Sensor protein DegS ADIP PF11559.3 EDN06091.1 - 0.0055 16.6 2.7 0.0088 15.9 1.9 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DivIC PF04977.10 EDN06091.1 - 0.011 15.1 2.1 0.021 14.3 1.5 1.4 1 0 0 1 1 1 0 Septum formation initiator Med28 PF11594.3 EDN06091.1 - 0.012 15.8 0.9 0.019 15.1 0.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 28 DUF2730 PF10805.3 EDN06091.1 - 0.012 15.2 0.5 0.019 14.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) IncA PF04156.9 EDN06091.1 - 0.013 15.1 0.7 0.017 14.6 0.5 1.1 1 0 0 1 1 1 0 IncA protein Fez1 PF06818.10 EDN06091.1 - 0.013 15.5 2.0 0.021 14.8 1.4 1.2 1 0 0 1 1 1 0 Fez1 zf-C3HC4_2 PF13923.1 EDN06091.1 - 0.013 15.4 5.5 0.038 14.0 3.8 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Seryl_tRNA_N PF02403.17 EDN06091.1 - 0.015 15.3 0.7 0.022 14.7 0.5 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain zf-RING_5 PF14634.1 EDN06091.1 - 0.02 14.6 7.4 0.042 13.5 5.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain HALZ PF02183.13 EDN06091.1 - 0.025 14.2 1.9 0.04 13.6 0.8 1.7 1 1 0 1 1 1 0 Homeobox associated leucine zipper Macoilin PF09726.4 EDN06091.1 - 0.038 12.2 3.3 0.048 11.9 2.3 1.1 1 0 0 1 1 1 0 Transmembrane protein HAUS5 PF14817.1 EDN06091.1 - 0.04 12.4 3.3 0.05 12.1 2.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Tropomyosin_1 PF12718.2 EDN06091.1 - 0.04 13.7 3.9 0.058 13.2 2.7 1.1 1 0 0 1 1 1 0 Tropomyosin like DUF4618 PF15397.1 EDN06091.1 - 0.049 12.9 2.4 0.066 12.5 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF641 PF04859.7 EDN06091.1 - 0.052 13.2 1.7 0.082 12.6 1.2 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.5 EDN06091.1 - 0.059 13.4 1.4 0.092 12.8 0.9 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.15 EDN06091.1 - 0.086 12.6 2.6 0.14 11.9 1.8 1.4 1 0 0 1 1 1 0 Prefoldin subunit RmuC PF02646.11 EDN06091.1 - 0.15 10.8 2.7 0.19 10.5 1.9 1.1 1 0 0 1 1 1 0 RmuC family Flg_hook PF02120.11 EDN06091.1 - 0.16 11.6 0.7 0.22 11.2 0.5 1.2 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK DUF3435 PF11917.3 EDN06092.1 - 6.4e-163 542.3 0.6 1e-162 541.6 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Topoisom_I_N PF02919.10 EDN06093.1 - 0.52 9.5 4.1 1.2 8.3 2.7 1.6 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF4187 PF13821.1 EDN06095.1 - 3.3e-18 64.9 3.7 9.1e-18 63.6 2.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EDN06095.1 - 8.2e-10 38.3 0.6 7.6e-09 35.2 0.4 2.3 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EDN06095.1 - 0.065 13.0 2.3 0.31 10.9 0.2 3.1 2 0 0 2 2 2 0 DExH-box splicing factor binding site CAP_N PF01213.14 EDN06096.1 - 0.036 13.3 1.5 0.074 12.3 1.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CPSase_L_D2 PF02786.12 EDN06097.1 - 6.8e-107 355.5 0.0 5.7e-84 280.6 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EDN06097.1 - 1.4e-41 141.1 0.0 3.2e-41 139.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EDN06097.1 - 8e-37 125.7 0.0 1.1e-17 64.0 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EDN06097.1 - 1.7e-36 125.6 0.1 4.2e-20 72.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EDN06097.1 - 2.1e-23 82.5 0.0 1.9e-08 33.4 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EDN06097.1 - 1.2e-18 67.1 0.1 3.6e-09 36.2 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EDN06097.1 - 5.6e-16 58.5 0.6 1e-06 28.2 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EDN06097.1 - 6.6e-08 32.2 0.0 0.0017 17.8 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.14 EDN06097.1 - 0.00012 21.6 0.2 0.41 10.1 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 EDN06097.1 - 0.00027 20.2 0.0 0.053 12.7 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain Epimerase PF01370.16 EDN06097.1 - 0.021 14.2 0.0 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family zf-MYND PF01753.13 EDN06098.1 - 1e-09 38.1 8.3 1e-09 38.1 5.8 2.2 2 0 0 2 2 2 1 MYND finger SET PF00856.23 EDN06098.1 - 0.0035 17.6 0.0 0.099 12.9 0.0 2.4 1 1 0 1 1 1 1 SET domain SPT2 PF08243.6 EDN06099.1 - 1.7e-06 28.2 19.3 1.7e-06 28.2 13.3 2.5 2 1 0 2 2 2 1 SPT2 chromatin protein Ribosomal_60s PF00428.14 EDN06100.1 - 1.7e-16 60.3 9.1 1.8e-16 60.2 6.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.16 EDN06101.1 - 1.5e-34 117.4 0.3 2.3e-34 116.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 EDN06101.1 - 0.093 12.7 0.1 0.3 11.1 0.0 1.7 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Carb_kinase PF01256.12 EDN06102.1 - 1.2e-29 103.3 0.0 1.9e-29 102.6 0.0 1.3 1 1 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EDN06102.1 - 0.013 14.6 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family DUF3245 PF11595.3 EDN06104.1 - 0.026 14.7 0.6 0.084 13.1 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Methyltransf_16 PF10294.4 EDN06106.1 - 0.011 15.2 0.0 0.36 10.2 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase Cys_Met_Meta_PP PF01053.15 EDN06107.1 - 4.5e-111 370.8 0.1 1.3e-97 326.5 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme GDC-P PF02347.11 EDN06107.1 - 0.066 11.8 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycine cleavage system P-protein Aminotran_1_2 PF00155.16 EDN06107.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II RNA_pol_Rbc25 PF08292.7 EDN06108.1 - 8.6e-34 116.3 0.0 2e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EDN06108.1 - 2e-14 53.4 0.7 3.1e-14 52.8 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 HlyIII PF03006.15 EDN06108.1 - 1e-05 25.0 0.1 1.7e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Haemolysin-III related NUFIP1 PF10453.4 EDN06109.1 - 3.5e-14 52.0 8.4 3.5e-14 52.0 5.8 2.6 2 1 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DSBA PF01323.15 EDN06111.1 - 0.12 11.8 0.2 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain eIF3_subunit PF08597.5 EDN06112.1 - 0.0017 18.0 6.4 0.0022 17.6 4.4 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit tRNA-synt_1c PF00749.16 EDN06112.1 - 0.02 13.5 3.4 0.024 13.3 2.3 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain PcfK PF14058.1 EDN06112.1 - 0.037 14.1 3.3 0.045 13.8 2.3 1.1 1 0 0 1 1 1 0 PcfK-like protein GPI-anchored PF10342.4 EDN06113.1 - 1.2e-17 64.1 0.1 1.2e-17 64.1 0.0 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pex14_N PF04695.8 EDN06113.1 - 0.42 10.6 7.4 0.77 9.8 5.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mito_fiss_reg PF05308.6 EDN06113.1 - 2.1 7.6 9.5 3.3 6.9 6.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator RRM_1 PF00076.17 EDN06114.1 - 9e-08 31.6 0.0 2.2e-05 24.0 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN06114.1 - 8.1e-07 28.8 0.0 0.029 14.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN06114.1 - 5.8e-06 26.2 0.0 0.00014 21.8 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.6 EDN06116.1 - 3.3e-07 30.0 0.4 3.3e-07 30.0 0.3 3.0 2 2 0 2 2 2 1 Sds3-like DDE_1 PF03184.14 EDN06117.1 - 1.4e-50 171.4 0.0 3.5e-50 170.1 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN06117.1 - 1.3e-08 34.5 0.0 3.2e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DNA_pol_E_B PF04042.11 EDN06118.1 - 0.079 12.1 0.0 0.13 11.4 0.0 1.3 1 1 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Coiled-coil_56 PF09813.4 EDN06120.1 - 0.0016 18.4 0.0 0.0018 18.1 0.0 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 EDN06121.1 - 1.9e-82 276.2 2.0 3.6e-82 275.3 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) TPR_12 PF13424.1 EDN06122.1 - 3.9e-16 58.7 0.0 1.4e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EDN06122.1 - 1.9e-12 46.6 0.1 0.004 17.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EDN06122.1 - 3.2e-05 23.5 0.1 0.016 14.8 0.0 2.9 2 1 1 3 3 3 1 TPR repeat TPR_2 PF07719.12 EDN06122.1 - 4.4e-05 23.0 0.7 3.2 7.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDN06122.1 - 0.00014 21.3 3.1 0.89 9.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDN06122.1 - 0.0011 18.9 0.8 1.9 8.8 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDN06122.1 - 0.0019 17.8 0.1 3.7 7.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDN06122.1 - 0.0021 18.7 0.0 0.3 11.8 0.0 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EDN06122.1 - 0.014 15.5 0.0 0.12 12.5 0.0 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDN06122.1 - 0.025 15.0 0.9 0.39 11.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EDN06122.1 - 0.046 14.1 0.3 1.5 9.4 0.0 2.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDN06122.1 - 0.1 12.9 0.5 7.7 6.9 0.1 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat STT3 PF02516.9 EDN06123.1 - 7.4e-115 384.6 38.0 1e-110 371.0 24.2 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit ATP-synt_E PF05680.7 EDN06124.1 - 3.1e-24 84.7 0.1 3.3e-24 84.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF3752 PF12572.3 EDN06124.1 - 0.065 13.3 0.3 0.082 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) WD40 PF00400.27 EDN06125.1 - 6.4e-16 57.5 5.7 8.6e-05 22.2 0.1 5.5 4 1 0 4 4 4 4 WD domain, G-beta repeat TP2 PF01254.13 EDN06125.1 - 0.072 13.4 4.2 3.6 7.9 0.4 3.1 3 0 0 3 3 3 0 Nuclear transition protein 2 Dynein_IC2 PF11540.3 EDN06125.1 - 0.13 11.6 1.3 0.31 10.4 0.2 2.1 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 MFS_1 PF07690.11 EDN06126.1 - 4.4e-25 88.1 16.9 4.4e-25 88.1 11.7 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily AF1Q PF15017.1 EDN06127.1 - 0.2 11.5 2.3 0.42 10.5 1.6 1.5 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator PMT PF02366.13 EDN06128.1 - 2.9e-80 269.1 15.5 2.9e-80 269.1 10.7 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EDN06128.1 - 1.1e-17 64.1 3.1 1.6e-17 63.7 0.8 1.9 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 EDN06128.1 - 6.3e-05 22.9 8.7 6.3e-05 22.9 6.1 3.3 5 1 0 5 5 5 1 Dolichyl-phosphate-mannose-protein mannosyltransferase 7TM_GPCR_Str PF10326.4 EDN06128.1 - 0.015 14.4 0.0 0.036 13.2 0.0 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str Pirin PF02678.11 EDN06129.1 - 1.9e-32 111.3 0.1 3.4e-32 110.4 0.1 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EDN06129.1 - 1.9e-20 72.8 0.0 1.6e-19 69.9 0.0 2.4 2 1 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EDN06129.1 - 2.2e-05 23.8 0.9 0.0004 19.8 1.2 2.3 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 EDN06129.1 - 0.13 11.6 0.1 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) SHD1 PF03983.7 EDN06130.1 - 1.4e-35 120.7 0.0 2.6e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 EDN06130.1 - 2.7e-34 116.3 5.9 3.3e-14 52.0 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.1 EDN06130.1 - 2.5e-29 100.5 7.7 9.3e-13 47.5 0.2 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.12 EDN06130.1 - 1e-19 69.7 0.1 2.6e-08 33.2 0.0 3.6 3 0 0 3 3 3 3 Variant SH3 domain SH3_3 PF08239.6 EDN06130.1 - 0.017 15.3 4.9 0.1 12.8 0.1 3.2 3 0 0 3 3 3 0 Bacterial SH3 domain TT_ORF2 PF02957.10 EDN06131.1 - 0.77 10.4 3.5 1.5 9.5 2.4 1.4 1 0 0 1 1 1 0 TT viral ORF2 HSCB_C PF07743.8 EDN06132.1 - 3.7e-21 75.3 0.6 9.1e-20 70.9 0.2 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EDN06132.1 - 2e-10 40.2 0.1 4.7e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain F-box PF00646.28 EDN06133.1 - 1.8e-06 27.4 0.8 4.6e-06 26.1 0.6 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN06133.1 - 3.8e-05 23.3 0.2 8.4e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EDN06133.1 - 0.018 15.0 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 PRANC domain DUF951 PF06107.6 EDN06133.1 - 0.1 12.0 0.2 0.26 10.8 0.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) PRP4 PF08799.6 EDN06135.1 - 6.5e-15 54.0 3.0 1.6e-14 52.8 2.1 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like WD40 PF00400.27 EDN06135.1 - 0.017 14.9 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat Nbas_N PF15492.1 EDN06135.1 - 0.12 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal Sigma70_ner PF04546.8 EDN06135.1 - 0.32 10.5 6.2 0.51 9.9 4.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region ERG4_ERG24 PF01222.12 EDN06136.1 - 3.2e-91 306.0 12.8 3.7e-91 305.8 8.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EDN06136.1 - 0.0002 20.7 0.2 0.0002 20.7 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Mpv17_PMP22 PF04117.7 EDN06136.1 - 0.12 12.0 5.8 0.42 10.2 0.2 3.3 4 0 0 4 4 4 0 Mpv17 / PMP22 family rve PF00665.21 EDN06137.1 - 3.3e-20 72.3 0.0 6.1e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EDN06137.1 - 4.1e-14 52.0 1.1 9.3e-14 50.8 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 EDN06137.1 - 0.022 14.6 0.7 0.072 13.0 0.1 2.0 1 1 1 2 2 2 0 Polycomb-like MTF2 factor 2 PQ-loop PF04193.9 EDN06139.1 - 3.3e-06 26.5 0.7 1.5e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 PQ loop repeat SpoIIE PF07228.7 EDN06140.1 - 3.1e-06 27.0 0.0 4.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EDN06140.1 - 1.4e-05 24.5 0.1 0.12 11.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EDN06140.1 - 4.8e-05 22.8 0.0 6.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C GMC_oxred_N PF00732.14 EDN06142.1 - 6e-07 28.9 0.0 0.0062 15.7 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.9 EDN06142.1 - 0.00022 21.1 0.0 0.00045 20.1 0.0 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN06142.1 - 0.00033 20.6 0.6 0.0014 18.6 0.2 2.3 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDN06142.1 - 0.0032 16.3 0.0 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EDN06142.1 - 0.0036 16.2 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EDN06142.1 - 0.018 13.9 0.2 0.023 13.6 0.1 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EDN06142.1 - 0.024 13.6 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EDN06142.1 - 0.18 10.2 0.1 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein GMC_oxred_C PF05199.8 EDN06143.1 - 2e-13 50.8 0.0 2.2e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase PWWP PF00855.12 EDN06145.1 - 2.9e-13 49.8 0.1 2.9e-13 49.8 0.0 2.6 1 1 0 2 2 2 1 PWWP domain RTC PF01137.16 EDN06146.1 - 1.6e-18 66.3 0.0 2.3e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EDN06146.1 - 6.3e-09 35.7 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DDE_1 PF03184.14 EDN06147.1 - 1.9e-27 95.8 0.0 8.2e-23 80.6 0.0 2.7 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_psq PF05225.11 EDN06147.1 - 3.6e-09 36.0 0.1 7.1e-09 35.0 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN06147.1 - 1.4e-08 34.4 0.1 5e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.1 EDN06147.1 - 0.0048 16.8 0.1 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain zf-CCHC_4 PF14392.1 EDN06147.1 - 0.034 13.8 0.5 0.034 13.8 0.3 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EDN06147.1 - 0.035 13.7 0.3 0.38 10.4 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle NUMOD1 PF07453.8 EDN06147.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 NUMOD1 domain zf-CCHC PF00098.18 EDN06147.1 - 0.23 11.4 1.0 0.41 10.6 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle 3-HAO PF06052.7 EDN06148.1 - 9.1e-54 180.9 0.0 1.1e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EDN06148.1 - 0.00013 21.4 0.0 0.00022 20.6 0.0 1.5 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EDN06148.1 - 0.0057 16.0 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EDN06148.1 - 0.035 13.7 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain TF_Zn_Ribbon PF08271.7 EDN06148.1 - 9.9 5.5 6.6 7.1 6.0 0.7 2.7 1 1 2 3 3 3 0 TFIIB zinc-binding CAP_GLY PF01302.20 EDN06149.1 - 9.7e-17 60.4 1.1 2.3e-16 59.2 0.3 2.0 2 0 0 2 2 2 1 CAP-Gly domain Spc7 PF08317.6 EDN06149.1 - 0.0029 16.3 18.0 0.024 13.3 4.1 3.0 2 1 1 3 3 3 2 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 EDN06149.1 - 0.0051 16.5 25.8 1.5 8.6 0.4 5.5 4 1 1 5 5 5 2 TATA element modulatory factor 1 DNA binding AAA_13 PF13166.1 EDN06149.1 - 0.013 14.0 12.0 0.011 14.2 5.4 2.2 2 0 0 2 2 2 0 AAA domain MogR_DNAbind PF12181.3 EDN06149.1 - 0.093 12.4 0.1 1 9.0 0.0 2.2 2 0 0 2 2 2 0 DNA binding domain of the motility gene repressor (MogR) MscS_porin PF12795.2 EDN06149.1 - 0.12 11.7 25.0 1.2 8.4 0.5 3.3 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Laminin_II PF06009.7 EDN06149.1 - 0.84 9.3 10.3 0.052 13.2 0.3 2.9 2 1 1 3 3 3 0 Laminin Domain II DUF1664 PF07889.7 EDN06149.1 - 1.1 9.1 12.2 2 8.2 1.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF812 PF05667.6 EDN06149.1 - 1.3 7.4 23.6 0.49 8.8 0.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.7 EDN06149.1 - 1.4 8.6 22.3 0.029 14.1 5.4 3.3 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.10 EDN06149.1 - 1.9 8.4 26.8 6.1 6.7 15.1 2.9 2 1 1 3 3 3 0 Fez1 PVL_ORF50 PF07768.6 EDN06149.1 - 1.9 8.4 11.4 0.061 13.3 0.6 2.8 2 1 1 3 3 3 0 PVL ORF-50-like family BLOC1_2 PF10046.4 EDN06149.1 - 2 8.6 13.7 4.6 7.4 0.8 4.1 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 EDN06149.1 - 5.6 7.0 13.9 4.3 7.4 0.5 3.6 3 1 1 4 4 3 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 EDN06149.1 - 5.6 7.4 27.3 1.2 9.5 0.1 4.4 4 0 0 4 4 4 0 SlyX IncA PF04156.9 EDN06149.1 - 6.9 6.2 36.1 2.1 7.8 9.1 3.4 3 1 1 4 4 3 0 IncA protein NPV_P10 PF05531.7 EDN06149.1 - 6.9 6.9 9.5 22 5.3 0.2 3.7 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.6 EDN06149.1 - 7.2 6.3 31.3 0.5 10.1 4.2 3.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) PspA_IM30 PF04012.7 EDN06149.1 - 8.4 5.6 27.2 1.7 7.9 1.4 3.3 2 1 1 3 3 3 0 PspA/IM30 family Pkinase PF00069.20 EDN06150.1 - 2.7e-27 95.5 0.0 6.1e-21 74.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06150.1 - 2.2e-07 30.2 0.0 0.00043 19.4 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EDN06150.1 - 0.00038 19.5 0.0 0.3 10.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EDN06150.1 - 0.012 15.3 0.4 0.12 12.1 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_S9 PF00326.16 EDN06151.1 - 3.4e-52 176.7 0.1 5.1e-52 176.1 0.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDN06151.1 - 6.6e-10 38.9 0.0 8.6e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN06151.1 - 9e-08 32.2 0.6 3.4e-07 30.3 0.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EDN06151.1 - 4.8e-06 26.1 0.7 7.9e-06 25.4 0.5 1.3 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.7 EDN06151.1 - 2.3e-05 23.0 0.3 0.0022 16.5 0.2 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Macro_2 PF14519.1 EDN06151.1 - 0.06 12.4 0.1 0.09 11.8 0.1 1.2 1 0 0 1 1 1 0 Macro-like domain Sec63 PF02889.11 EDN06152.1 - 2.1e-78 263.7 9.7 3.8e-34 118.3 0.1 4.3 2 2 2 4 4 4 4 Sec63 Brl domain DEAD PF00270.24 EDN06152.1 - 1.6e-55 187.1 0.7 1.1e-31 109.5 0.0 4.1 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EDN06152.1 - 1.5e-17 64.0 0.2 2.2e-09 37.3 0.0 2.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDN06152.1 - 1.4e-10 40.8 0.0 1.1e-09 38.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EDN06152.1 - 4.6e-08 33.2 0.9 0.0008 19.5 0.1 4.1 3 1 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EDN06152.1 - 0.00025 20.6 0.1 3 7.2 0.0 4.1 4 1 0 4 4 4 2 AAA-like domain T2SE PF00437.15 EDN06152.1 - 0.0014 17.5 0.0 0.32 9.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.11 EDN06152.1 - 0.0021 17.3 0.0 0.44 9.7 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein AAA_19 PF13245.1 EDN06152.1 - 0.0086 15.8 0.0 2.2 8.0 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 EDN06152.1 - 0.012 15.1 0.0 0.053 12.9 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family MutS_I PF01624.15 EDN06153.1 - 1.8e-22 79.5 0.0 2.8e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EDN06153.1 - 4.3e-08 33.3 0.1 7.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain II Ureidogly_hydro PF04115.7 EDN06154.1 - 2.4e-14 53.0 0.0 3.3e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate hydrolase ADH_N PF08240.7 EDN06155.1 - 2.5e-07 30.4 1.2 3.8e-07 29.8 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN06155.1 - 0.046 13.2 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Tim17 PF02466.14 EDN06156.1 - 7.1e-25 87.5 2.9 9.7e-25 87.0 1.4 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family HTH_Tnp_Tc3_2 PF01498.13 EDN06157.1 - 5.4e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.1 EDN06157.1 - 4.4e-05 22.9 0.1 0.00013 21.3 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_29 PF13551.1 EDN06157.1 - 6.8e-05 22.9 0.0 0.00015 21.8 0.0 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EDN06157.1 - 0.00016 22.4 0.2 0.00062 20.5 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EDN06157.1 - 0.0022 17.9 0.1 0.009 16.0 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EDN06157.1 - 0.004 16.5 0.1 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.1 EDN06157.1 - 0.0087 15.6 0.6 0.029 14.0 0.1 2.0 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.11 EDN06157.1 - 0.092 12.0 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Brix PF04427.13 EDN06158.1 - 5.2e-29 101.2 0.0 7.1e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF4285 PF14113.1 EDN06158.1 - 0.051 13.5 0.3 0.41 10.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4285) RNase_P_p30 PF01876.11 EDN06159.1 - 7.4e-51 171.3 0.0 1e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Pkinase PF00069.20 EDN06160.1 - 2.5e-56 190.7 0.0 2.9e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06160.1 - 4.3e-18 65.3 0.0 6e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN06160.1 - 4.9e-07 29.7 0.0 0.00015 21.5 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN06160.1 - 0.011 15.2 0.1 0.032 13.8 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EDN06160.1 - 0.054 12.8 0.1 0.095 12.0 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EDN06160.1 - 0.063 12.3 0.1 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDN06160.1 - 0.07 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Aconitase_B_N PF11791.3 EDN06160.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Aconitate B N-terminal domain tRNA-synt_1 PF00133.17 EDN06161.1 - 1.5e-164 548.3 2.2 1.3e-129 433.0 0.1 3.0 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EDN06161.1 - 8.4e-15 54.3 0.2 8.9e-06 24.6 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EDN06161.1 - 4e-06 26.2 2.0 8.1e-05 21.9 0.0 2.6 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EDN06161.1 - 0.001 18.2 0.0 0.029 13.5 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EDN06161.1 - 0.0092 14.8 0.0 0.76 8.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (R) tRNA-synt_1f PF01921.13 EDN06161.1 - 0.037 12.6 0.0 0.063 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) C1q PF00386.16 EDN06164.1 - 0.11 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 C1q domain DUF3597 PF12200.3 EDN06164.1 - 0.44 10.9 4.3 1.6 9.1 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) PAT1 PF09770.4 EDN06164.1 - 5 5.2 11.8 5.9 5.0 8.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HMG-CoA_red PF00368.13 EDN06165.1 - 0.11 11.0 6.4 0.026 13.2 2.2 1.5 2 0 0 2 2 2 0 Hydroxymethylglutaryl-coenzyme A reductase DUF3431 PF11913.3 EDN06166.1 - 8e-89 296.9 0.1 1e-88 296.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) MFS_1 PF07690.11 EDN06168.1 - 2.3e-07 29.8 16.6 2.8e-06 26.3 6.8 3.9 4 1 0 4 4 4 3 Major Facilitator Superfamily Myb_DNA-bind_4 PF13837.1 EDN06169.1 - 0.018 15.1 1.9 0.019 15.1 0.1 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain ATP_transf PF09830.4 EDN06170.1 - 2.8e-21 75.0 0.0 5e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase zf-C2H2_4 PF13894.1 EDN06171.1 - 0.0033 17.6 16.5 0.13 12.6 0.0 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN06171.1 - 0.0038 17.4 20.1 1 9.8 0.0 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type TEX19 PF15553.1 EDN06171.1 - 0.013 15.3 1.2 2 8.2 0.0 2.5 2 0 0 2 2 2 0 Testis-expressed protein 19 RPN7 PF10602.4 EDN06172.1 - 1.1e-41 142.1 0.0 1.8e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EDN06172.1 - 3.1e-10 40.2 0.1 1.4e-09 38.2 0.0 2.1 2 0 0 2 2 2 1 PCI domain Phage_sheath_1 PF04984.9 EDN06172.1 - 0.11 10.8 0.0 0.2 10.0 0.0 1.3 1 0 0 1 1 1 0 Phage tail sheath protein DSBA PF01323.15 EDN06173.1 - 9.6e-07 28.5 0.0 1.4e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain adh_short PF00106.20 EDN06174.1 - 3.6e-14 53.0 0.1 6e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 EDN06174.1 - 0.12 12.2 0.7 0.82 9.5 0.7 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Rad33 PF08730.5 EDN06175.1 - 0.0032 16.9 0.0 0.0053 16.2 0.0 1.2 1 0 0 1 1 1 1 Rad33 NTR2 PF15458.1 EDN06176.1 - 1.1e-78 263.9 18.9 1.1e-78 263.9 13.1 1.6 2 0 0 2 2 2 1 Nineteen complex-related protein 2 LSM PF01423.17 EDN06177.1 - 1.1e-19 69.7 0.8 1.2e-19 69.5 0.6 1.0 1 0 0 1 1 1 1 LSM domain Peptidase_M1 PF01433.15 EDN06178.1 - 1.3e-06 27.7 0.0 0.0013 17.8 0.0 3.2 3 0 0 3 3 3 2 Peptidase family M1 VGCC_beta4Aa_N PF12052.3 EDN06178.1 - 0.28 11.0 3.0 5.7 6.8 0.2 2.6 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal CDP-OH_P_transf PF01066.16 EDN06179.1 - 4.5e-15 55.7 6.1 4.5e-15 55.7 4.2 2.7 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase LTD PF00932.14 EDN06180.1 - 0.085 12.9 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Lamin Tail Domain DUF3659 PF12396.3 EDN06181.1 - 2.1e-18 65.7 7.0 3.3e-18 65.1 4.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) AAA_PrkA PF08298.6 EDN06181.1 - 0.087 11.5 0.0 0.24 10.0 0.0 1.6 2 0 0 2 2 2 0 PrkA AAA domain DUF3659 PF12396.3 EDN06182.1 - 1.7e-37 126.9 14.6 5.9e-24 83.5 0.2 4.0 3 1 1 4 4 4 4 Protein of unknown function (DUF3659) LCCL PF03815.14 EDN06183.1 - 5.2e-12 45.5 0.3 7.7e-12 45.0 0.2 1.2 1 0 0 1 1 1 1 LCCL domain DUF3435 PF11917.3 EDN06187.1 - 2.8e-60 204.2 0.1 6.6e-43 146.9 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) PX PF00787.19 EDN06189.1 - 4.1e-06 26.5 0.0 8.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 PX domain PX PF00787.19 EDN06191.1 - 6.4e-15 54.9 0.0 1.2e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 PX domain SAS4 PF15460.1 EDN06192.1 - 7.8e-36 122.0 7.3 1.5e-35 121.1 5.1 1.5 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DUF605 PF04652.11 EDN06192.1 - 0.012 15.0 24.9 0.019 14.3 17.2 1.3 1 0 0 1 1 1 0 Vta1 like PEHE PF15275.1 EDN06192.1 - 0.019 15.4 2.9 0.019 15.4 2.0 4.0 3 2 0 4 4 4 0 PEHE domain HVSL PF09749.4 EDN06193.1 - 1.6e-75 253.1 0.0 5.3e-53 179.5 0.0 2.1 1 1 1 2 2 2 2 Uncharacterised conserved protein Pal1 PF08316.6 EDN06194.1 - 7e-06 26.5 0.7 1.3e-05 25.6 0.5 1.4 1 0 0 1 1 1 1 Pal1 cell morphology protein Methyltransf_28 PF02636.12 EDN06195.1 - 4.9e-40 137.5 0.0 6.6e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EDN06195.1 - 0.016 14.2 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PALP PF00291.20 EDN06196.1 - 1.6e-41 142.4 0.0 2.5e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Scm3 PF10384.4 EDN06197.1 - 1.2e-24 85.5 0.4 2.1e-24 84.7 0.3 1.4 1 0 0 1 1 1 1 Centromere protein Scm3 APG6 PF04111.7 EDN06198.1 - 2.2e-130 434.3 0.0 2.6e-130 434.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Rpr2 PF04032.11 EDN06198.1 - 0.067 13.0 0.5 0.54 10.1 0.0 2.5 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Peroxin-13_N PF04088.8 EDN06200.1 - 7.7e-59 198.1 0.0 1.2e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EDN06200.1 - 8.9e-09 34.7 0.0 1.5e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDN06200.1 - 1.2e-06 27.7 0.0 2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain ERO1 PF04137.10 EDN06201.1 - 9.6e-133 442.6 0.0 1.2e-132 442.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) TPP_enzyme_N PF02776.13 EDN06202.1 - 1.3e-44 151.7 0.1 2.6e-44 150.7 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDN06202.1 - 9.8e-36 122.5 0.0 1.9e-35 121.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EDN06202.1 - 8.2e-17 61.1 0.0 3.6e-16 59.0 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPR_11 PF13414.1 EDN06203.1 - 2.5e-26 91.1 7.4 2.2e-11 43.2 0.1 4.6 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 EDN06203.1 - 3e-26 89.9 2.8 1.7e-09 36.8 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EDN06203.1 - 4e-25 85.6 3.5 9.2e-08 31.4 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDN06203.1 - 3.1e-19 67.7 5.7 2.4e-05 24.5 0.0 6.2 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDN06203.1 - 1.3e-16 60.8 7.0 7.5e-06 26.4 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDN06203.1 - 2.9e-16 58.2 6.5 0.00058 19.8 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EDN06203.1 - 6.4e-15 55.2 4.6 0.00028 21.1 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EDN06203.1 - 2.3e-14 52.0 0.1 2.4e-05 23.7 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDN06203.1 - 1.4e-13 50.5 5.2 1.7e-07 31.0 0.1 4.1 3 2 1 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDN06203.1 - 1.1e-11 43.5 4.3 0.00044 19.8 0.0 6.3 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 EDN06203.1 - 1.9e-11 43.9 0.8 0.0011 19.0 0.1 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDN06203.1 - 2e-09 37.1 0.4 0.0041 16.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EDN06203.1 - 5.2e-08 32.9 0.7 7.1e-05 22.8 0.1 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDN06203.1 - 5.7e-08 32.7 2.5 1.2 9.7 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.1 EDN06203.1 - 0.00025 20.1 0.4 0.35 9.8 0.2 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 EDN06203.1 - 0.0053 16.6 0.4 3.2 7.6 0.0 4.0 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 EDN06203.1 - 0.0076 16.0 0.0 2.1 8.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EDN06203.1 - 0.019 14.9 3.6 0.33 10.9 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TOM20_plant PF06552.7 EDN06203.1 - 0.02 14.5 0.0 3 7.4 0.0 2.9 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF1641 PF07849.6 EDN06203.1 - 0.13 11.9 0.2 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) RRM_1 PF00076.17 EDN06204.1 - 3.6e-24 84.1 0.1 3.7e-15 55.2 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN06204.1 - 1.5e-17 63.2 0.2 3.1e-11 43.0 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN06204.1 - 8.8e-09 35.0 0.0 0.0025 17.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 EDN06205.1 - 1.4e-10 40.5 0.0 2.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNA_pol_Rbc25 PF08292.7 EDN06207.1 - 1.6 8.9 4.9 0.37 10.9 0.1 2.4 2 2 0 2 2 2 0 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EDN06208.1 - 6.2e-14 51.8 0.1 9.6e-14 51.2 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EDN06208.1 - 5.4e-11 42.4 0.0 8.2e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.6 EDN06209.1 - 1.2e-16 60.3 9.8 4.9e-15 55.1 6.8 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) ATP-synt_ab PF00006.20 EDN06210.1 - 2.2e-57 194.0 0.0 3.3e-57 193.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDN06210.1 - 8.8e-28 97.0 0.3 2.2e-27 95.7 0.2 1.7 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Tex_N PF09371.5 EDN06210.1 - 0.0099 15.2 0.1 0.021 14.1 0.1 1.5 1 0 0 1 1 1 1 Tex-like protein N-terminal domain THF_DHG_CYH PF00763.18 EDN06211.1 - 1.7e-16 60.2 0.0 2.6e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EDN06211.1 - 3.8e-12 45.5 0.1 4.4e-09 35.6 0.0 2.3 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SPC25 PF06703.6 EDN06212.1 - 8.4e-50 168.5 0.0 9.5e-50 168.3 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF106 PF01956.11 EDN06213.1 - 2.5e-55 186.5 0.1 3.5e-55 186.0 0.1 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 Fasciclin PF02469.17 EDN06214.1 - 0.00029 20.8 0.0 0.00047 20.1 0.0 1.3 1 1 0 1 1 1 1 Fasciclin domain MMS19_N PF14500.1 EDN06215.1 - 6.9e-46 156.6 1.7 5.5e-34 117.6 0.0 3.5 4 1 1 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EDN06215.1 - 1.1e-43 149.5 4.9 1.5e-43 149.1 0.0 2.7 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 EDN06215.1 - 8.5e-05 22.7 0.9 0.22 11.8 0.0 3.7 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EDN06215.1 - 0.056 13.5 0.0 29 5.1 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat MMS19_C PF12460.3 EDN06216.1 - 3.7e-16 58.8 1.3 6.6e-16 58.0 0.4 1.7 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT PF02985.17 EDN06216.1 - 0.00047 20.0 2.2 6.3 7.1 0.1 3.5 3 0 0 3 3 3 2 HEAT repeat AflR PF08493.5 EDN06216.1 - 0.95 8.4 6.8 1.3 7.9 4.7 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein HEAT_EZ PF13513.1 EDN06216.1 - 5.4 7.6 6.5 21 5.7 1.3 3.3 3 1 0 3 3 3 0 HEAT-like repeat adh_short PF00106.20 EDN06221.1 - 2.2e-16 60.2 0.4 3.7e-16 59.4 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN06221.1 - 6.5e-10 38.9 0.2 1.1e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EDN06221.1 - 0.00071 18.5 0.1 0.00098 18.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EDN06221.1 - 0.0025 17.6 0.0 0.0035 17.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EDN06221.1 - 0.0038 17.3 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF3842 PF12953.2 EDN06221.1 - 0.016 15.3 0.3 0.031 14.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) DUF3940 PF13076.1 EDN06221.1 - 0.033 13.7 1.0 0.1 12.1 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) NAD_binding_10 PF13460.1 EDN06221.1 - 0.046 13.7 0.2 0.091 12.7 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding NAD_binding_4 PF07993.7 EDN06222.1 - 7.1e-62 208.5 0.0 1.4e-61 207.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EDN06222.1 - 3.5e-45 154.1 0.0 3.1e-24 85.1 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme adh_short PF00106.20 EDN06222.1 - 1.5e-32 112.7 8.2 1.1e-30 106.8 1.5 2.7 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 EDN06222.1 - 2e-17 63.4 2.0 7.9e-14 51.7 0.6 2.5 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EDN06222.1 - 2.1e-15 57.1 0.0 3.9e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EDN06222.1 - 4.6e-15 55.6 0.0 5.1e-09 35.9 0.0 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDN06222.1 - 9.7e-11 40.8 0.0 2.9e-07 29.4 0.0 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EDN06222.1 - 1.9e-06 26.9 0.1 0.0043 15.9 0.0 3.2 3 0 0 3 3 3 2 RmlD substrate binding domain NAD_binding_10 PF13460.1 EDN06222.1 - 5.3e-06 26.5 0.7 0.008 16.1 0.2 3.3 3 1 1 4 4 4 2 NADH(P)-binding Polysacc_synt_2 PF02719.10 EDN06222.1 - 1.6e-05 23.9 0.3 0.1 11.4 0.0 3.3 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein DFP PF04127.10 EDN06222.1 - 0.027 14.0 0.4 0.095 12.3 0.4 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein ApbA PF02558.11 EDN06222.1 - 0.036 13.5 0.1 0.1 12.0 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Eno-Rase_NADH_b PF12242.3 EDN06222.1 - 0.063 13.0 0.4 0.27 11.0 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CBF PF03914.12 EDN06224.1 - 2.3e-49 166.9 0.1 5.3e-49 165.8 0.1 1.6 1 0 0 1 1 1 1 CBF/Mak21 family DUF3201 PF11447.3 EDN06224.1 - 0.061 12.7 0.1 0.21 10.9 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3201) Utp12 PF04003.7 EDN06224.1 - 0.07 13.0 0.2 0.23 11.3 0.1 2.0 1 1 0 1 1 1 0 Dip2/Utp12 Family Mt_ATP-synt_B PF05405.9 EDN06225.1 - 2.5e-51 173.3 12.0 3e-51 173.1 8.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3573 PF12097.3 EDN06225.1 - 0.11 11.1 2.6 0.13 10.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) PBP_sp32 PF07222.7 EDN06225.1 - 1.2 8.2 5.1 2 7.5 3.6 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pkinase_Tyr PF07714.12 EDN06226.1 - 2e-08 33.6 0.0 8.8e-08 31.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EDN06226.1 - 9.2e-08 31.5 0.0 7.7e-07 28.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Sel1 PF08238.7 EDN06227.1 - 4e-19 68.5 12.3 5.8e-08 33.1 0.2 3.4 3 0 0 3 3 3 3 Sel1 repeat TFIIF_beta PF02270.10 EDN06230.1 - 2.7e-77 260.2 6.5 1.1e-75 254.9 4.5 2.0 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Bestrophin PF01062.16 EDN06232.1 - 0.014 14.3 0.4 0.089 11.7 0.2 2.1 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel DUF1040 PF06288.8 EDN06232.1 - 0.22 11.7 4.0 0.096 12.9 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1040) RVT_2 PF07727.9 EDN06233.1 - 4.1e-52 176.5 0.0 6e-52 176.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN06233.1 - 5.4e-16 58.7 0.1 2.1e-15 56.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DUF4219 PF13961.1 EDN06233.1 - 0.021 14.2 1.9 0.048 13.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) gag_pre-integrs PF13976.1 EDN06233.1 - 0.022 14.3 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain CAP_N PF01213.14 EDN06233.1 - 3.7 6.7 10.2 12 5.1 7.1 1.9 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CP2 PF04516.10 EDN06234.1 - 1.4e-86 289.4 0.0 1.9e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 CP2 transcription factor DDE_1 PF03184.14 EDN06236.1 - 1.3e-44 151.8 0.0 4.4e-44 150.2 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN06236.1 - 2.7e-12 46.3 0.0 1.5e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN06236.1 - 2e-10 40.0 0.2 4.5e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN06236.1 - 9.7e-06 25.3 0.0 2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease AcetylCoA_hydro PF02550.10 EDN06237.1 - 2.6e-36 125.2 0.0 4.1e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain DDE_1 PF03184.14 EDN06237.1 - 5.6e-24 84.4 0.1 2.9e-23 82.1 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease Myc_N PF01056.13 EDN06238.1 - 0.012 14.8 0.2 0.012 14.8 0.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Adeno_terminal PF02459.10 EDN06238.1 - 0.023 12.8 0.4 0.024 12.7 0.3 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein LIN37 PF15306.1 EDN06238.1 - 0.077 12.9 1.2 0.083 12.8 0.8 1.1 1 0 0 1 1 1 0 LIN37 WTX PF09422.5 EDN06238.1 - 0.13 11.2 2.2 0.15 11.0 1.5 1.1 1 0 0 1 1 1 0 WTX protein Ribosomal_60s PF00428.14 EDN06238.1 - 0.19 12.1 2.0 0.24 11.8 1.4 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2701 PF10857.3 EDN06238.1 - 0.19 11.4 1.1 0.31 10.8 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2701) DUF3682 PF12446.3 EDN06238.1 - 0.32 11.2 3.2 0.36 11.1 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) PAH PF02671.16 EDN06239.1 - 2e-46 155.3 1.0 6.5e-17 60.8 0.3 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EDN06239.1 - 1.7e-41 140.0 1.0 3.1e-41 139.2 0.1 2.0 2 0 0 2 2 2 1 Sin3 family co-repressor Adeno_shaft PF00608.12 EDN06240.1 - 0.11 12.0 0.0 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) Pyr_redox_3 PF13738.1 EDN06241.1 - 2e-28 99.8 0.0 6.7e-28 98.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDN06241.1 - 1.3e-21 76.4 0.0 5.3e-21 74.4 0.0 1.9 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EDN06241.1 - 9.3e-15 54.3 1.2 1.3e-11 44.0 0.1 2.9 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EDN06241.1 - 8.1e-13 48.7 0.0 1.4e-09 38.1 0.0 2.8 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN06241.1 - 1.3e-10 41.5 0.2 0.013 15.9 0.0 3.5 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDN06241.1 - 4.2e-08 32.6 3.4 6.3e-05 22.1 0.6 2.7 2 1 1 3 3 3 2 FAD binding domain 3HCDH_N PF02737.13 EDN06241.1 - 1.1e-05 25.2 0.5 0.0046 16.6 0.1 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EDN06241.1 - 2.1e-05 23.2 0.9 0.0022 16.5 0.0 3.2 3 1 1 4 4 4 1 HI0933-like protein F420_oxidored PF03807.12 EDN06241.1 - 2.5e-05 24.6 0.4 0.014 15.8 0.1 3.1 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EDN06241.1 - 5.4e-05 22.6 0.1 0.16 11.3 0.0 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 EDN06241.1 - 6e-05 22.2 0.1 0.065 12.3 0.0 2.9 3 0 0 3 3 3 2 Thi4 family NAD_Gly3P_dh_N PF01210.18 EDN06241.1 - 7e-05 22.6 0.1 0.004 16.8 0.0 2.3 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 EDN06241.1 - 0.00012 21.2 0.3 0.038 13.1 0.1 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EDN06241.1 - 0.00017 21.2 0.0 0.1 12.1 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.1 EDN06241.1 - 0.00023 21.0 0.0 0.0026 17.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDN06241.1 - 0.00024 20.1 1.5 0.78 8.5 0.1 3.4 2 1 1 4 4 4 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EDN06241.1 - 0.00037 20.5 0.2 0.29 11.2 0.1 2.8 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EDN06241.1 - 0.0006 18.7 0.1 0.22 10.3 0.0 2.8 2 1 1 3 3 3 1 Glucose inhibited division protein A IlvN PF07991.7 EDN06241.1 - 0.0011 18.3 1.0 0.0017 17.7 0.2 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain FAD_binding_2 PF00890.19 EDN06241.1 - 0.0027 16.6 1.1 0.047 12.5 0.1 2.7 2 1 1 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.1 EDN06241.1 - 0.0048 17.1 1.2 0.035 14.3 0.1 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EDN06241.1 - 0.0052 16.5 3.7 2.5 7.8 0.2 3.5 2 2 0 2 2 2 2 FAD-NAD(P)-binding TrkA_N PF02254.13 EDN06241.1 - 0.0056 16.6 0.3 1.2 9.1 0.0 2.8 2 1 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.7 EDN06241.1 - 0.0067 15.3 0.1 0.53 9.1 0.0 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein DNA_pol3_a_NI PF14480.1 EDN06241.1 - 0.019 14.6 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus I NAD_binding_10 PF13460.1 EDN06241.1 - 0.039 13.9 0.6 3.5 7.6 0.1 2.5 2 0 0 2 2 2 0 NADH(P)-binding Mur_ligase PF01225.20 EDN06241.1 - 0.044 13.8 0.1 0.095 12.7 0.1 1.6 1 0 0 1 1 1 0 Mur ligase family, catalytic domain ThiF PF00899.16 EDN06241.1 - 0.09 12.5 0.9 12 5.7 0.0 2.8 2 0 0 2 2 2 0 ThiF family DUF605 PF04652.11 EDN06242.1 - 5.2 6.3 12.9 6.4 6.0 9.0 1.0 1 0 0 1 1 1 0 Vta1 like WD40 PF00400.27 EDN06243.1 - 6.4e-10 38.5 3.8 0.31 11.0 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat PCI PF01399.22 EDN06244.1 - 8.4e-11 42.1 0.0 3.5e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 EDN06244.1 - 1.1e-05 24.9 0.1 1.8e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_14 PF13428.1 EDN06244.1 - 0.0042 17.5 2.6 2.3 9.0 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN06244.1 - 0.0045 17.2 0.3 0.074 13.3 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDN06244.1 - 0.0081 16.0 0.2 6.3 6.8 0.3 3.3 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDN06244.1 - 0.012 15.3 0.0 1.5 8.7 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDN06244.1 - 0.095 12.5 0.1 3.3 7.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat RVT_1 PF00078.22 EDN06245.1 - 6.8e-20 71.3 0.0 1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN06245.1 - 2.6e-14 53.7 0.0 4.5e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 RNase H BORG_CEP PF14957.1 EDN06247.1 - 7.9 7.4 10.1 0.52 11.2 1.7 2.3 2 0 0 2 2 2 0 Cdc42 effector Pkinase PF00069.20 EDN06248.1 - 2.1e-05 23.8 0.0 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EDN06248.1 - 0.00044 19.3 0.1 0.0007 18.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 EDN06248.1 - 0.028 13.6 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 EDN06248.1 - 0.03 14.0 0.1 0.057 13.1 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RVT_2 PF07727.9 EDN06249.1 - 1.3e-32 112.7 0.0 3.1e-17 62.3 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN06249.1 - 3.4e-06 27.1 0.0 8.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain MFS_1 PF07690.11 EDN06252.1 - 2.1e-45 154.9 56.0 4.3e-45 153.9 37.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN06252.1 - 7.4e-14 50.8 26.2 1.1e-13 50.3 18.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EDN06252.1 - 9.9e-13 47.4 16.5 9.9e-13 47.4 11.4 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter Sel1 PF08238.7 EDN06253.1 - 3.1e-29 100.7 16.5 2.4e-07 31.1 0.0 5.3 5 0 0 5 5 5 5 Sel1 repeat Chitin_synth_2 PF03142.10 EDN06254.1 - 6.9e-293 971.8 0.9 8.9e-293 971.4 0.6 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EDN06254.1 - 1.5e-17 63.9 1.0 3.5e-17 62.7 0.7 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDN06254.1 - 8.7e-15 55.1 0.0 3.7e-13 49.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EDN06254.1 - 2.8e-07 30.2 0.0 7.7e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EDN06254.1 - 1e-05 24.9 0.0 0.00011 21.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EDN06254.1 - 0.0029 17.2 0.0 0.053 13.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 MFS_1 PF07690.11 EDN06256.1 - 9.7e-31 106.7 16.8 1.2e-30 106.4 11.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN06256.1 - 1.1e-11 44.0 11.4 1.4e-11 43.6 7.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EDN06256.1 - 1.6e-08 33.2 5.9 1.9e-08 33.0 4.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EDN06256.1 - 0.0056 15.1 9.2 0.0085 14.5 4.4 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein Fasciclin PF02469.17 EDN06257.1 - 2.3e-26 92.2 0.2 6.6e-16 58.4 0.1 2.5 2 1 0 2 2 2 2 Fasciclin domain LRR_9 PF14580.1 EDN06257.1 - 0.031 13.8 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat WD40 PF00400.27 EDN06259.1 - 5e-08 32.5 0.5 1.9e-07 30.6 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat NOA36 PF06524.7 EDN06259.1 - 4.1 6.5 11.9 7.5 5.7 8.2 1.3 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 EDN06259.1 - 4.8 6.7 6.6 7.7 6.0 4.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PARP PF00644.15 EDN06260.1 - 8.4e-64 214.7 1.6 2.4e-63 213.2 0.0 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EDN06260.1 - 4.7e-42 142.8 0.0 7.4e-42 142.1 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EDN06260.1 - 1.4e-21 76.1 0.2 3.9e-21 74.7 0.1 1.8 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 EDN06260.1 - 1.6e-07 31.3 0.1 6e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EDN06260.1 - 0.00033 20.4 0.1 0.00082 19.1 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF500 PF04366.7 EDN06261.1 - 6.4e-30 103.1 0.4 1.1e-29 102.3 0.3 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) FtsK_SpoIIIE PF01580.13 EDN06262.1 - 0.061 12.7 0.0 0.061 12.7 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family RTA1 PF04479.8 EDN06265.1 - 1.4e-48 165.3 2.1 1.8e-48 164.9 1.5 1.1 1 0 0 1 1 1 1 RTA1 like protein Tmemb_161AB PF10268.4 EDN06265.1 - 0.15 10.5 0.8 0.25 9.7 0.6 1.2 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB DUF885 PF05960.6 EDN06266.1 - 0.075 12.1 0.0 0.081 12.0 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DDE_1 PF03184.14 EDN06269.1 - 2.2e-14 53.1 0.1 4.2e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN06269.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain RVT_1 PF00078.22 EDN06270.1 - 1.1e-22 80.4 0.0 2.5e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EDN06270.1 - 5.2e-16 58.0 0.8 1.3e-15 56.8 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EDN06270.1 - 1.4e-08 34.8 0.0 4.5e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.1 EDN06270.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.5 EDN06270.1 - 0.022 14.1 0.0 0.056 12.8 0.0 1.7 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 EDN06270.1 - 0.052 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.15 EDN06270.1 - 0.093 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease WD40 PF00400.27 EDN06271.1 - 2e-17 62.3 8.1 4.7e-07 29.4 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Mg_trans_NIPA PF05653.9 EDN06272.1 - 1.9e-59 201.0 3.4 2.7e-59 200.5 2.4 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EDN06272.1 - 2.4e-05 24.5 0.6 2.4e-05 24.5 0.4 2.8 2 1 0 2 2 2 1 Multidrug resistance efflux transporter Secretin PF00263.16 EDN06272.1 - 0.054 12.8 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein Striatin PF08232.7 EDN06273.1 - 0.022 15.0 2.7 1.1 9.5 0.5 2.8 2 0 0 2 2 2 0 Striatin family SCP-1 PF05483.7 EDN06273.1 - 0.1 10.3 0.3 0.16 9.6 0.2 1.2 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Calpain_inhib PF00748.14 EDN06273.1 - 0.98 9.7 9.0 0.057 13.7 1.3 2.7 2 1 1 3 3 3 0 Calpain inhibitor GRAM PF02893.15 EDN06274.1 - 9.9e-17 60.2 0.0 2e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 GRAM domain TPR_11 PF13414.1 EDN06275.1 - 1.3e-10 40.7 0.0 4.5e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDN06275.1 - 9e-07 28.3 0.1 0.092 12.7 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDN06275.1 - 4.2e-05 22.9 0.0 0.022 14.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EDN06275.1 - 0.0015 18.3 0.0 0.0046 16.7 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EDN06275.1 - 0.0022 18.1 0.0 0.006 16.6 0.0 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EDN06275.1 - 0.0046 16.8 0.0 0.57 10.1 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN06275.1 - 0.009 16.3 0.0 0.13 12.6 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN06275.1 - 0.018 15.6 0.1 6.6 7.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDN06275.1 - 0.033 14.8 0.0 1.2 9.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Asp PF00026.18 EDN06276.1 - 1.2e-57 195.6 0.0 1.4e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDN06276.1 - 7.4e-07 29.5 0.0 0.009 16.4 0.0 3.0 3 1 0 3 3 3 2 Aspartyl protease TAXi_N PF14543.1 EDN06276.1 - 0.00075 19.4 0.0 0.015 15.2 0.0 2.6 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal RVP PF00077.15 EDN06276.1 - 0.00086 19.1 0.0 0.74 9.7 0.0 2.8 3 0 0 3 3 3 2 Retroviral aspartyl protease TAXi_C PF14541.1 EDN06276.1 - 0.0037 16.8 0.0 0.011 15.3 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EDN06276.1 - 0.13 12.1 0.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease CAF1 PF04857.15 EDN06277.1 - 1.7e-43 148.8 0.0 6.9e-37 127.2 0.0 2.2 1 1 1 2 2 2 2 CAF1 family ribonuclease NDUF_B12 PF08122.7 EDN06278.1 - 3.8e-16 58.5 1.7 5.8e-16 57.9 1.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family WD40 PF00400.27 EDN06279.1 - 1.3e-31 107.3 2.5 1.5e-06 27.8 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EDN06279.1 - 0.0085 15.5 0.0 0.32 10.5 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain AMP-binding PF00501.23 EDN06280.1 - 1.1e-51 175.5 0.0 3.7e-25 88.1 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EDN06280.1 - 1.5e-15 57.9 0.0 4.1e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Myb_DNA-binding PF00249.26 EDN06282.1 - 6.6e-10 38.8 0.0 1.4e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN06282.1 - 4.4e-06 26.6 0.2 1e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain BCS1_N PF08740.6 EDN06283.1 - 2.2e-34 118.7 0.0 3.7e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN06283.1 - 1.1e-19 70.9 0.0 5e-19 68.8 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN06283.1 - 0.00053 20.0 0.6 0.0016 18.4 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EDN06283.1 - 0.0057 17.4 0.5 0.035 14.9 0.0 2.5 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EDN06283.1 - 0.008 15.5 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDN06283.1 - 0.039 13.6 0.0 0.1 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN06283.1 - 0.047 13.8 0.0 0.2 11.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EDN06283.1 - 0.056 13.3 0.3 0.41 10.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EDN06283.1 - 0.066 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 EDN06283.1 - 0.077 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF815 PF05673.8 EDN06283.1 - 0.081 11.8 0.0 0.53 9.1 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF815) PPV_E1_C PF00519.12 EDN06283.1 - 0.093 11.3 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase RuvB_N PF05496.7 EDN06283.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Nsp1_C PF05064.8 EDN06284.1 - 0.055 13.1 0.4 0.09 12.4 0.3 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region PRTase_2 PF15609.1 EDN06286.1 - 0.051 12.8 0.4 0.33 10.2 0.2 2.1 2 0 0 2 2 2 0 Phosphoribosyl transferase APH PF01636.18 EDN06287.1 - 1.1e-06 28.5 0.8 0.00021 21.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EDN06287.1 - 1.9e-05 23.9 0.1 3.2e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EDN06287.1 - 8.5e-05 21.7 0.2 0.00016 20.8 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family AceK PF06315.6 EDN06287.1 - 0.00089 17.6 0.1 0.0013 17.1 0.0 1.2 1 0 0 1 1 1 1 Isocitrate dehydrogenase kinase/phosphatase (AceK) Pkinase_Tyr PF07714.12 EDN06287.1 - 0.016 14.2 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.15 EDN06287.1 - 0.024 14.2 0.0 0.074 12.6 0.0 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EDN06287.1 - 0.094 11.3 0.0 0.13 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF3435 PF11917.3 EDN06289.1 - 7.8e-167 555.2 0.3 1.1e-166 554.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EDN06289.1 - 5.2e-06 26.2 0.1 0.00068 19.3 0.0 2.4 2 0 0 2 2 2 2 Phage integrase family OmpH PF03938.9 EDN06289.1 - 0.42 10.5 6.9 0.43 10.4 0.0 2.7 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) CNH PF00780.17 EDN06290.1 - 6.8e-47 160.1 0.0 8.3e-24 84.4 0.0 2.3 1 1 1 2 2 2 2 CNH domain RhoGEF PF00621.15 EDN06290.1 - 1.5e-31 109.6 2.0 2.2e-31 109.1 0.2 2.0 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 EDN06290.1 - 1.7e-13 50.6 0.0 2.8e-12 46.7 0.0 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EDN06290.1 - 0.00053 20.1 0.0 0.0035 17.5 0.0 2.3 2 0 0 2 2 2 1 PH domain RabGAP-TBC PF00566.13 EDN06291.1 - 1.6e-40 138.9 0.0 2.9e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 EDN06291.1 - 0.0063 16.0 0.0 0.017 14.6 0.0 1.8 1 1 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.1 EDN06291.1 - 0.014 15.5 5.2 0.076 13.1 0.1 3.1 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 EDN06291.1 - 0.019 14.8 0.1 0.019 14.8 0.1 3.5 3 0 0 3 3 3 0 EF-hand domain DUF605 PF04652.11 EDN06291.1 - 0.61 9.4 7.4 0.038 13.3 1.4 1.6 2 0 0 2 2 2 0 Vta1 like DUF2457 PF10446.4 EDN06291.1 - 2.7 6.6 14.0 2.8 6.5 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) MxiH PF09392.5 EDN06293.1 - 0.0045 17.5 2.6 0.0045 17.5 1.8 3.1 3 1 0 3 3 3 1 Type III secretion needle MxiH like IncA PF04156.9 EDN06293.1 - 0.0096 15.5 23.1 0.015 14.8 11.4 2.8 2 1 0 2 2 2 2 IncA protein TMPIT PF07851.8 EDN06293.1 - 4 6.4 7.7 11 5.0 5.4 1.8 1 0 0 1 1 1 0 TMPIT-like protein adh_short_C2 PF13561.1 EDN06294.1 - 5.9e-19 68.7 0.0 9.1e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN06294.1 - 4.2e-17 62.5 0.9 6.1e-17 62.0 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN06294.1 - 2.6e-05 23.9 0.5 6.1e-05 22.7 0.1 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EDN06294.1 - 0.094 11.5 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein APH PF01636.18 EDN06296.1 - 1.1e-09 38.3 0.4 1.3e-06 28.3 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN06296.1 - 0.0074 15.8 0.2 0.0099 15.4 0.1 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase AMP-binding PF00501.23 EDN06297.1 - 1.6e-72 244.2 0.0 1.9e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN06297.1 - 5e-12 46.6 0.1 1.3e-11 45.2 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AAA PF00004.24 EDN06298.1 - 3.2e-41 140.6 0.0 5.1e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN06298.1 - 2.3e-07 31.0 0.2 0.0044 17.1 0.1 2.4 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 EDN06298.1 - 2.2e-06 27.7 0.0 4.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EDN06298.1 - 3.6e-05 23.5 0.1 0.00011 21.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EDN06298.1 - 4.1e-05 22.6 0.0 6.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 EDN06298.1 - 0.00064 18.8 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EDN06298.1 - 0.00081 19.4 0.1 0.0038 17.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EDN06298.1 - 0.00093 18.9 0.4 0.0024 17.5 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EDN06298.1 - 0.001 19.0 0.1 0.0021 18.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EDN06298.1 - 0.0035 16.7 0.0 0.007 15.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EDN06298.1 - 0.007 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EDN06298.1 - 0.0086 15.7 0.2 0.58 9.7 0.1 2.4 1 1 1 2 2 2 1 NACHT domain TIP49 PF06068.8 EDN06298.1 - 0.012 14.3 0.1 0.023 13.4 0.0 1.5 1 1 0 1 1 1 0 TIP49 C-terminus AAA_14 PF13173.1 EDN06298.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EDN06298.1 - 0.017 14.2 0.4 0.23 10.5 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_17 PF13207.1 EDN06298.1 - 0.02 15.7 0.3 0.047 14.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EDN06298.1 - 0.029 13.9 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EDN06298.1 - 0.036 14.3 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDN06298.1 - 0.038 13.3 1.7 0.53 9.6 0.3 2.3 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 EDN06298.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EDN06298.1 - 0.057 12.2 0.0 0.084 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 EDN06298.1 - 0.066 12.1 0.0 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EDN06298.1 - 0.071 13.2 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EDN06298.1 - 0.094 11.8 0.1 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EDN06298.1 - 0.11 11.7 0.3 0.37 9.9 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein CPT PF07931.7 EDN06298.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.1 EDN06298.1 - 0.13 11.8 0.2 0.29 10.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.21 EDN06299.1 - 2.1e-42 143.8 0.0 2.9e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EDN06299.1 - 1.3e-06 27.8 0.1 3.3e-06 26.6 0.0 1.7 1 1 1 2 2 2 1 Fungal ubiquitin-associated domain RWD PF05773.17 EDN06299.1 - 0.039 13.8 0.2 0.07 13.0 0.1 1.6 1 1 0 1 1 1 0 RWD domain DUF2095 PF09868.4 EDN06299.1 - 0.072 12.8 0.2 0.13 12.0 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) Cyclin_N PF00134.18 EDN06300.1 - 3.6e-06 26.5 0.0 7.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Xpo1 PF08389.7 EDN06300.1 - 0.023 14.6 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 Exportin 1-like protein TMEM247 PF15444.1 EDN06300.1 - 0.1 12.4 1.7 0.38 10.5 0.2 2.2 2 0 0 2 2 2 0 Transmembrane protein 247 ABC_tran PF00005.22 EDN06301.1 - 4.2e-47 159.8 0.0 2.4e-23 82.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EDN06301.1 - 1.1e-20 74.7 0.5 0.00046 20.2 0.0 4.3 3 1 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 EDN06301.1 - 4.8e-19 67.9 0.8 4.8e-19 67.9 0.6 2.9 4 0 0 4 4 2 1 ABC transporter SMC_N PF02463.14 EDN06301.1 - 4.1e-11 42.5 0.1 0.0024 17.1 0.0 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDN06301.1 - 4.2e-09 35.8 0.3 0.00051 19.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EDN06301.1 - 2.1e-07 30.2 0.0 0.0004 19.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EDN06301.1 - 5.6e-07 30.0 6.1 0.021 15.1 0.0 3.8 4 1 0 4 4 3 2 AAA domain AAA_17 PF13207.1 EDN06301.1 - 1.1e-06 29.4 0.3 0.013 16.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EDN06301.1 - 3.5e-06 27.3 0.1 0.057 13.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EDN06301.1 - 1.9e-05 24.8 0.0 0.27 11.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EDN06301.1 - 6.2e-05 22.2 0.0 0.082 11.9 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.1 EDN06301.1 - 8.6e-05 22.5 0.1 0.28 11.1 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EDN06301.1 - 0.0001 22.2 0.0 0.21 11.5 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase NACHT PF05729.7 EDN06301.1 - 0.00012 21.7 0.1 0.5 10.0 0.0 2.5 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.17 EDN06301.1 - 0.00013 22.1 1.8 0.89 9.7 0.0 3.5 3 0 0 3 3 3 2 RNA helicase MobB PF03205.9 EDN06301.1 - 0.0002 21.0 0.3 0.0069 16.0 0.1 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EDN06301.1 - 0.00026 21.4 0.0 0.53 10.7 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 EDN06301.1 - 0.00039 20.6 0.0 0.67 10.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EDN06301.1 - 0.00047 20.0 1.2 0.15 11.9 0.0 2.9 4 0 0 4 4 2 1 AAA domain NB-ARC PF00931.17 EDN06301.1 - 0.00072 18.5 0.0 0.39 9.5 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain Arch_ATPase PF01637.13 EDN06301.1 - 0.00073 19.3 0.4 0.89 9.2 0.0 3.2 3 1 0 3 3 3 1 Archaeal ATPase AAA_10 PF12846.2 EDN06301.1 - 0.00093 18.7 1.3 0.76 9.1 0.2 2.9 3 0 0 3 3 2 2 AAA-like domain AAA_28 PF13521.1 EDN06301.1 - 0.00095 19.1 0.0 0.77 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDN06301.1 - 0.0012 18.5 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EDN06301.1 - 0.0018 17.7 0.1 0.31 10.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EDN06301.1 - 0.0078 16.1 0.4 0.83 9.6 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EDN06301.1 - 0.0085 15.9 0.0 3.8 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EDN06301.1 - 0.018 14.8 0.1 18 5.0 0.0 3.8 3 1 1 4 4 3 0 Dynamin family AAA_30 PF13604.1 EDN06301.1 - 0.024 14.1 0.6 9.7 5.7 0.0 3.4 4 0 0 4 4 4 0 AAA domain PduV-EutP PF10662.4 EDN06301.1 - 0.027 13.9 0.5 2.1 7.8 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 EDN06301.1 - 0.033 13.1 0.0 4.2 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ArgK PF03308.11 EDN06301.1 - 0.045 12.5 1.5 3.8 6.2 0.1 2.9 3 0 0 3 3 3 0 ArgK protein VirE PF05272.6 EDN06301.1 - 0.047 13.1 0.1 1.8 8.0 0.0 2.9 3 0 0 3 3 3 0 Virulence-associated protein E ATP-synt_ab PF00006.20 EDN06301.1 - 0.053 13.0 0.0 0.43 10.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DAP3 PF10236.4 EDN06301.1 - 0.055 12.3 0.1 9.7 5.0 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF2813 PF11398.3 EDN06301.1 - 0.058 12.4 0.0 13 4.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) ABC_ATPase PF09818.4 EDN06301.1 - 0.059 11.9 0.0 8.7 4.7 0.0 3.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_24 PF13479.1 EDN06301.1 - 0.088 12.3 0.6 14 5.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 EDN06301.1 - 0.14 11.8 0.2 6.9 6.3 0.1 2.5 2 0 0 2 2 2 0 NTPase DUF87 PF01935.12 EDN06301.1 - 0.17 11.7 1.2 13 5.4 0.0 3.1 4 0 0 4 4 2 0 Domain of unknown function DUF87 DUF3584 PF12128.3 EDN06301.1 - 9.2 3.4 7.2 0.81 6.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) HPP PF04982.8 EDN06302.1 - 5.5e-24 84.3 3.5 5.5e-24 84.3 2.4 1.7 2 0 0 2 2 2 1 HPP family MFS_1 PF07690.11 EDN06302.1 - 0.00026 19.8 0.9 0.037 12.7 0.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3159 PF11361.3 EDN06302.1 - 0.16 11.3 3.6 0.2 11.1 2.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3159) Sec62 PF03839.11 EDN06303.1 - 0.016 14.6 3.4 0.016 14.6 2.4 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 Mob_synth_C PF06463.8 EDN06305.1 - 0.016 14.8 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C GFO_IDH_MocA PF01408.17 EDN06306.1 - 6.2e-09 36.4 0.0 6.8e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Kelch_4 PF13418.1 EDN06307.1 - 9.3e-15 54.1 6.5 3.6e-06 26.6 0.4 4.9 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EDN06307.1 - 1.3e-12 47.3 6.8 5.4e-08 32.6 0.0 5.6 6 0 0 6 6 6 1 Kelch motif Kelch_6 PF13964.1 EDN06307.1 - 1.1e-08 34.8 4.9 0.021 15.0 0.4 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 EDN06307.1 - 1.3e-05 25.1 13.3 0.035 14.2 0.2 5.4 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EDN06307.1 - 4.5e-05 22.9 5.9 0.14 11.7 0.2 4.1 4 0 0 4 4 4 2 Kelch motif SKG6 PF08693.5 EDN06307.1 - 0.002 17.4 0.9 0.002 17.4 0.6 2.6 3 0 0 3 3 3 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 EDN06307.1 - 0.11 11.3 0.1 0.63 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) Trp_oprn_chp PF09534.5 EDN06307.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Regulator_TrmB PF11495.3 EDN06308.1 - 0.078 11.9 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB MARVEL PF01284.18 EDN06309.1 - 3.9e-07 30.0 0.8 4.7e-07 29.7 0.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain RRM_1 PF00076.17 EDN06311.1 - 9.7e-29 98.8 0.0 6.8e-14 51.2 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN06311.1 - 1.9e-22 79.0 0.0 1.2e-11 44.4 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN06311.1 - 5.8e-07 29.2 0.0 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 EDN06311.1 - 0.016 13.7 2.9 0.022 13.2 2.0 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) ArfGap PF01412.13 EDN06312.1 - 3e-18 65.6 0.0 5.2e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GTP_EFTU PF00009.22 EDN06313.1 - 3.4e-54 183.1 0.0 7.3e-54 182.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EDN06313.1 - 1.6e-24 85.5 0.0 3.9e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EDN06313.1 - 7.6e-09 35.3 0.1 2.1e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDN06313.1 - 0.00018 21.5 0.0 0.00059 19.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Vps5 PF09325.5 EDN06314.1 - 1.6e-15 57.0 2.8 2.8e-15 56.2 1.9 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EDN06314.1 - 4.1e-08 32.9 0.0 8.8e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 PX domain TPR_12 PF13424.1 EDN06314.1 - 0.031 14.2 0.5 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat GFA PF04828.9 EDN06315.1 - 2.7e-15 56.0 0.2 4e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Herpes_UL49_1 PF03117.9 EDN06315.1 - 0.0018 17.4 0.9 0.0023 17.1 0.6 1.1 1 0 0 1 1 1 1 UL49 family Rpr2 PF04032.11 EDN06315.1 - 0.059 13.2 0.6 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain C1_1 PF00130.17 EDN06315.1 - 0.41 10.4 4.0 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Epimerase PF01370.16 EDN06316.1 - 2.4e-14 53.3 0.1 4.1e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EDN06316.1 - 8.2e-07 29.3 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EDN06316.1 - 8e-06 25.2 0.0 1.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EDN06316.1 - 0.00055 18.7 0.0 0.1 11.2 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EDN06316.1 - 0.0026 17.7 0.0 0.0091 16.0 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Silic_transp PF03842.8 EDN06316.1 - 0.031 12.3 0.0 0.045 11.8 0.0 1.1 1 0 0 1 1 1 0 Silicon transporter NAD_binding_4 PF07993.7 EDN06316.1 - 0.054 12.4 0.0 0.26 10.1 0.0 2.1 2 1 0 2 2 2 0 Male sterility protein Thoc2 PF11732.3 EDN06317.1 - 4.5e-31 106.4 0.0 1.4e-30 104.8 0.0 1.9 1 0 0 1 1 1 1 Transcription- and export-related complex subunit RGM_C PF06534.8 EDN06317.1 - 0.18 10.9 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus Tho2 PF11262.3 EDN06318.1 - 2.2e-94 315.8 0.0 2.9e-94 315.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 CN_hydrolase PF00795.17 EDN06320.1 - 0.15 11.4 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 0 Carbon-nitrogen hydrolase Fim-adh_lectin PF09222.5 EDN06320.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Fimbrial adhesin F17-AG, lectin domain DUF364 PF04016.7 EDN06323.1 - 0.091 12.0 0.0 0.099 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF364) JAB PF01398.16 EDN06324.1 - 6.6e-08 32.3 0.1 1e-07 31.6 0.1 1.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RNA_pol_3_Rpc31 PF11705.3 EDN06326.1 - 1.8e-44 152.4 25.9 4.2e-44 151.2 17.9 1.6 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 EDN06326.1 - 3.3 7.5 8.3 3.9 7.2 5.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAD_binding_1 PF00667.15 EDN06327.1 - 3.7e-20 72.3 0.0 7.8e-17 61.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.16 EDN06327.1 - 1.2e-08 35.4 0.0 9.9e-08 32.5 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain ETF PF01012.16 EDN06328.1 - 7.9e-37 126.4 0.2 1e-36 126.1 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF488 PF04343.8 EDN06329.1 - 2.5e-14 53.7 0.0 4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF488 RTC PF01137.16 EDN06330.1 - 1.6e-34 118.6 0.0 8.1e-32 109.8 0.0 3.2 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Exo_endo_phos PF03372.18 EDN06330.1 - 4.9e-17 62.6 0.1 8.3e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BRI3BP PF14965.1 EDN06332.1 - 4.4 6.6 8.3 0.08 12.3 0.6 1.9 2 1 1 3 3 3 0 Negative regulator of p53/TP53 DUF2439 PF10382.4 EDN06334.1 - 9.8e-26 89.7 0.0 1.8e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) DUF3405 PF11885.3 EDN06336.1 - 2.5e-172 573.5 0.0 3e-172 573.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Mcp5_PH PF12814.2 EDN06337.1 - 6.1e-45 152.1 0.1 1.3e-44 151.0 0.1 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 EDN06337.1 - 0.0012 19.0 0.4 0.0052 16.9 0.0 2.2 2 0 0 2 2 2 1 PH domain zf-C3HC4_2 PF13923.1 EDN06338.1 - 1.7e-08 34.3 10.4 2.9e-08 33.6 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN06338.1 - 5.8e-08 32.2 4.8 9.7e-08 31.5 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN06338.1 - 2e-07 30.7 7.2 3.4e-07 29.9 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EDN06338.1 - 5.9e-07 29.1 8.7 9.7e-07 28.4 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDN06338.1 - 3e-06 26.7 10.4 5.1e-06 26.0 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EDN06338.1 - 7.2e-06 25.5 2.3 7.2e-06 25.5 1.6 1.7 2 0 0 2 2 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_4 PF15227.1 EDN06338.1 - 0.0015 18.3 9.1 0.003 17.4 6.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EDN06338.1 - 0.0038 16.9 5.3 0.0079 15.8 3.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EDN06338.1 - 0.032 13.7 2.6 0.054 13.0 1.8 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cript PF10235.4 EDN06338.1 - 0.057 13.7 3.6 0.16 12.3 2.5 1.7 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT zf-rbx1 PF12678.2 EDN06338.1 - 0.97 9.5 5.2 2.5 8.2 3.6 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger rve PF00665.21 EDN06339.1 - 1.4e-16 60.7 0.0 7.2e-16 58.3 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EDN06339.1 - 2.6e-11 43.3 0.4 4.9e-10 39.1 0.0 2.5 2 1 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EDN06339.1 - 0.0033 16.8 0.1 0.0082 15.5 0.0 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger SRI PF08236.6 EDN06341.1 - 9.5e-21 73.5 12.6 9.5e-21 73.5 8.7 2.0 1 1 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.21 EDN06341.1 - 0.0015 18.3 0.5 0.0032 17.3 0.3 1.6 1 0 0 1 1 1 1 WW domain Las1 PF04031.8 EDN06341.1 - 0.096 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Las1-like DUF3287 PF11690.3 EDN06341.1 - 0.17 11.9 4.9 0.17 11.9 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) eIF-6 PF01912.13 EDN06342.1 - 1.1e-28 99.6 0.0 1.3e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 eIF-6 family DUF3431 PF11913.3 EDN06343.1 - 1.9e-41 141.9 4.7 8.9e-29 100.5 1.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3431) Ku PF02735.11 EDN06347.1 - 9e-36 123.1 0.0 1.7e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EDN06347.1 - 6.2e-33 114.1 0.0 8.3e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EDN06347.1 - 9.9e-15 54.8 0.2 2.8e-14 53.4 0.1 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm Ferrochelatase PF00762.14 EDN06348.1 - 2.3e-66 223.9 0.0 2.6e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase ADH_zinc_N PF00107.21 EDN06349.1 - 1.3e-26 92.6 0.7 2.9e-26 91.5 0.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN06349.1 - 1.1e-17 65.1 0.1 2e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN06349.1 - 1.6e-10 40.7 0.0 2.9e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EDN06349.1 - 0.02 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain rve PF00665.21 EDN06351.1 - 5.1e-20 71.7 0.0 1.9e-19 69.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-H2C2 PF09337.5 EDN06351.1 - 0.04 13.3 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger MFS_1 PF07690.11 EDN06352.1 - 4.7e-23 81.4 32.1 7.2e-23 80.8 22.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 EDN06352.1 - 0.0015 17.1 27.7 0.0015 17.0 4.9 3.1 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like PPR_3 PF13812.1 EDN06353.1 - 0.0001 22.2 0.2 6.2 7.3 0.0 6.1 5 1 2 7 7 7 2 Pentatricopeptide repeat domain SE PF08491.5 EDN06354.1 - 2.1e-96 321.9 0.0 2.6e-96 321.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EDN06354.1 - 5e-12 45.5 0.0 8.7e-11 41.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 EDN06354.1 - 1e-07 31.1 0.9 2.2e-05 23.4 0.7 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EDN06354.1 - 1.1e-07 31.1 0.8 3.9e-06 26.0 1.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EDN06354.1 - 1.1e-06 27.8 0.0 1.4e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EDN06354.1 - 2.3e-05 24.3 0.7 5.2e-05 23.2 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EDN06354.1 - 0.00012 21.2 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDN06354.1 - 0.00026 20.9 0.0 0.00039 20.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN06354.1 - 0.0005 19.2 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EDN06354.1 - 0.0012 17.8 0.1 0.0038 16.1 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 EDN06354.1 - 0.0013 17.2 0.2 0.0029 16.1 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EDN06354.1 - 0.0078 16.6 0.5 0.026 14.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EDN06354.1 - 0.0086 15.5 0.2 0.014 14.7 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GDI PF00996.13 EDN06354.1 - 0.038 12.2 0.0 0.057 11.7 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Trp_halogenase PF04820.9 EDN06354.1 - 0.05 12.2 0.1 0.55 8.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 EDN06354.1 - 0.11 12.2 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 EDN06354.1 - 0.12 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PAP_assoc PF03828.14 EDN06355.1 - 9.5e-09 35.0 0.7 7.4e-08 32.2 0.5 2.4 1 1 0 1 1 1 1 Cid1 family poly A polymerase CorA PF01544.13 EDN06358.1 - 2.8e-10 39.7 0.8 6.3e-10 38.5 0.6 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Tecti-min-caps PF09300.5 EDN06360.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Tectiviridae, minor capsid Exo_endo_phos PF03372.18 EDN06362.1 - 4.3e-05 23.5 0.0 6.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DCP1 PF06058.8 EDN06363.1 - 2.7e-17 62.9 0.0 7.5e-17 61.5 0.0 1.6 1 1 0 1 1 1 1 Dcp1-like decapping family DUF2305 PF10230.4 EDN06364.1 - 1.9e-56 191.4 0.0 3e-56 190.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 EDN06364.1 - 5.5e-05 22.9 0.8 0.0042 16.8 0.6 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN06364.1 - 0.00051 19.9 0.0 0.00076 19.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family EMP24_GP25L PF01105.19 EDN06364.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DEAD PF00270.24 EDN06365.1 - 3e-11 43.1 0.0 6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN06365.1 - 5.4e-05 23.1 0.1 0.00076 19.3 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDN06365.1 - 0.11 12.6 0.1 0.39 10.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain CobT PF06213.7 EDN06366.1 - 0.00052 19.2 4.4 0.00081 18.6 3.1 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT BUD22 PF09073.5 EDN06366.1 - 0.012 14.7 0.7 0.014 14.4 0.5 1.1 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.8 EDN06366.1 - 0.043 13.4 4.8 0.073 12.6 3.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF972 PF06156.8 EDN06366.1 - 0.071 13.4 1.5 0.12 12.6 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) RXT2_N PF08595.6 EDN06366.1 - 0.21 11.3 2.4 0.31 10.8 1.7 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.5 EDN06366.1 - 2.1 8.6 8.9 4.2 7.6 6.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HNH_2 PF13391.1 EDN06367.1 - 2.3e-14 52.9 0.0 5.6e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease SMK-1 PF04802.10 EDN06368.1 - 9.4e-60 201.4 0.6 2e-59 200.4 0.4 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DUF914 PF06027.7 EDN06369.1 - 2e-107 358.9 16.6 2.6e-107 358.5 11.5 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EDN06369.1 - 1.4e-05 25.0 28.9 2.6e-05 24.2 7.5 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EDN06369.1 - 0.012 15.2 6.0 0.012 15.2 4.1 2.6 2 2 0 2 2 2 0 Triose-phosphate Transporter family DUF1669 PF07894.7 EDN06370.1 - 0.098 11.8 0.9 0.18 10.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) FUSC PF04632.7 EDN06370.1 - 1.1 7.5 11.0 0.19 10.1 4.8 1.7 2 0 0 2 2 2 0 Fusaric acid resistance protein family STE3 PF02076.10 EDN06371.1 - 2e-100 335.5 14.5 2.3e-100 335.3 10.0 1.0 1 0 0 1 1 1 1 Pheromone A receptor SSB PF00436.20 EDN06372.1 - 1.8e-15 56.6 0.0 2.5e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family DUF4203 PF13886.1 EDN06374.1 - 6.5e-05 22.4 3.1 0.0001 21.8 2.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Toxin_56 PF15534.1 EDN06374.1 - 0.051 14.0 0.8 0.11 12.9 0.6 1.5 1 0 0 1 1 1 0 Putative toxin 56 Erf4 PF10256.4 EDN06375.1 - 1.9e-34 118.0 0.0 2.6e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Adap_comp_sub PF00928.16 EDN06376.1 - 2.5e-67 226.7 0.0 1.9e-53 181.2 0.0 2.2 1 1 1 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EDN06376.1 - 0.0093 15.6 1.2 0.058 13.1 0.4 2.3 1 1 1 2 2 2 1 Clathrin adaptor complex small chain APH PF01636.18 EDN06377.1 - 8.6e-08 32.2 0.2 7.6e-07 29.1 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family EcKinase PF02958.15 EDN06377.1 - 0.0048 16.0 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 EDN06377.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Myb_DNA-bind_6 PF13921.1 EDN06378.1 - 1.1e-05 25.4 0.0 3.8e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN06378.1 - 0.1 12.6 0.2 0.1 12.6 0.1 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain Pkinase PF00069.20 EDN06379.1 - 3e-59 200.2 0.1 5.9e-58 196.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06379.1 - 8.1e-32 110.3 0.0 2.5e-30 105.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EDN06379.1 - 1.6e-05 24.1 0.0 5.1e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDN06379.1 - 0.0021 17.0 0.0 0.0032 16.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN06379.1 - 0.0031 17.2 0.0 0.0077 15.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EDN06379.1 - 0.039 13.2 0.0 0.19 11.0 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Ank PF00023.25 EDN06380.1 - 0.0044 16.7 0.4 0.011 15.5 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 EDN06380.1 - 0.0045 17.2 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN06380.1 - 0.005 16.9 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Acetyltransf_10 PF13673.1 EDN06380.1 - 0.011 15.8 0.0 0.24 11.5 0.0 2.8 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.2 EDN06380.1 - 0.053 13.8 0.0 0.23 11.8 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) ABC_membrane PF00664.18 EDN06381.1 - 1.2e-40 139.7 11.1 1.2e-40 139.7 7.7 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 EDN06381.1 - 8.1e-20 71.5 0.0 4.6e-19 69.0 0.0 2.3 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EDN06381.1 - 0.00059 19.1 0.1 0.74 8.9 0.0 2.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EDN06381.1 - 0.0079 16.5 0.0 0.026 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EDN06381.1 - 0.022 13.9 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDN06381.1 - 0.031 14.0 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Dynamin family AAA_29 PF13555.1 EDN06381.1 - 0.035 13.6 0.0 0.14 11.6 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF999 PF06198.6 EDN06381.1 - 0.054 13.2 0.6 0.26 11.0 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF999) AAA_21 PF13304.1 EDN06381.1 - 0.077 12.9 0.1 0.33 10.8 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EDN06381.1 - 0.097 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EDN06381.1 - 0.13 12.1 0.2 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EDN06382.1 - 2e-25 89.7 0.1 1.1e-24 87.2 0.1 2.1 1 1 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EDN06382.1 - 7.3e-20 71.5 2.5 9.2e-20 71.1 1.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EDN06382.1 - 4.7e-06 25.9 1.6 0.00025 20.3 0.2 2.1 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EDN06382.1 - 0.052 13.5 2.9 0.18 11.7 2.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 EDN06382.1 - 0.063 12.6 0.3 13 5.1 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 EDN06382.1 - 0.084 12.2 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EDN06382.1 - 0.095 12.6 0.1 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 EDN06382.1 - 0.16 11.9 3.3 1.6 8.6 0.0 2.6 2 1 1 3 3 3 0 AAA domain DUF2841 PF11001.3 EDN06383.1 - 7.3e-47 158.3 0.7 1.2e-46 157.6 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) GATase PF00117.23 EDN06384.1 - 2.4e-26 92.4 0.0 8.7e-26 90.5 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EDN06384.1 - 0.0012 18.2 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C26 SAC3_GANP PF03399.11 EDN06386.1 - 7.6e-56 188.9 2.1 1e-55 188.4 1.5 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Zip PF02535.17 EDN06386.1 - 1.8e-35 122.4 4.7 9.6e-26 90.5 0.1 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter PCI_Csn8 PF10075.4 EDN06386.1 - 2.4e-05 24.1 0.1 8.1e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EDN06387.1 - 4.2e-56 189.7 2.1 5.4e-56 189.3 1.5 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EDN06387.1 - 1.2e-05 25.0 0.1 9.8e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 Sec8_exocyst PF04048.9 EDN06388.1 - 2.5e-48 163.3 0.5 1.1e-47 161.2 0.1 2.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EDN06388.1 - 2.5e-08 33.2 0.1 5.7e-08 31.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 EDN06388.1 - 0.00061 18.0 0.3 0.0018 16.5 0.1 1.8 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Peptidase_M24 PF00557.19 EDN06389.1 - 4.6e-41 140.6 0.0 6.2e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EDN06389.1 - 1.3e-23 83.9 0.0 8.8e-21 74.7 0.0 2.8 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain IBN_N PF03810.14 EDN06390.1 - 0.04 13.8 0.1 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Importin-beta N-terminal domain SOR_SNZ PF01680.12 EDN06391.1 - 8.7e-110 365.2 3.9 8.7e-110 365.2 2.7 1.6 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 EDN06391.1 - 1.9e-10 40.2 3.7 2.4e-07 30.0 0.0 2.6 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EDN06391.1 - 0.0015 17.8 0.6 0.2 10.8 0.0 2.9 2 1 1 3 3 3 1 Histidine biosynthesis protein Dus PF01207.12 EDN06391.1 - 0.0019 17.0 0.4 0.74 8.5 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.16 EDN06391.1 - 0.0054 15.8 0.0 0.068 12.2 0.0 2.5 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 EDN06391.1 - 0.011 14.6 0.4 0.28 10.1 0.0 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase PEP_mutase PF13714.1 EDN06391.1 - 0.038 13.2 1.3 0.19 10.9 0.2 2.4 2 1 1 3 3 3 0 Phosphoenolpyruvate phosphomutase NMO PF03060.10 EDN06391.1 - 0.31 10.1 6.5 0.4 9.7 0.6 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase FUN14 PF04930.10 EDN06392.1 - 1.9e-08 34.4 0.0 4.1e-08 33.4 0.0 1.5 2 0 0 2 2 2 1 FUN14 family ORC2 PF04084.9 EDN06393.1 - 3.4e-91 305.4 0.0 4.2e-91 305.1 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ArgJ PF01960.13 EDN06394.1 - 1e-134 448.8 0.1 1.2e-134 448.6 0.1 1.0 1 0 0 1 1 1 1 ArgJ family SecY PF00344.15 EDN06395.1 - 3.4e-97 325.4 8.4 4.2e-97 325.1 5.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EDN06395.1 - 2.6e-18 65.2 0.3 7.8e-18 63.6 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p DUF3584 PF12128.3 EDN06396.1 - 0.00053 17.4 22.4 0.0007 17.0 15.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF869 PF05911.6 EDN06396.1 - 0.027 12.7 26.5 0.032 12.4 17.5 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) DDR PF08841.5 EDN06396.1 - 0.038 12.8 0.0 0.076 11.8 0.0 1.4 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain ACR_tran PF00873.14 EDN06396.1 - 0.29 8.4 2.3 0.39 8.0 1.6 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF3450 PF11932.3 EDN06396.1 - 1.6 7.9 16.6 1 8.5 5.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.6 EDN06396.1 - 2 7.8 21.5 0.3 10.5 4.9 3.3 1 1 2 3 3 3 0 Phage minor structural protein GP20 APG6 PF04111.7 EDN06396.1 - 4.3 6.2 34.9 0.93 8.4 11.3 3.0 1 1 2 3 3 3 0 Autophagy protein Apg6 MFS_1 PF07690.11 EDN06399.1 - 0.034 12.8 7.7 0.039 12.6 5.4 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily PsbX PF06596.6 EDN06399.1 - 9.1 6.0 6.7 1.6 8.4 0.1 3.0 3 1 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) MUG113 PF13455.1 EDN06400.1 - 3e-30 104.4 1.4 5.5e-30 103.6 0.9 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EDN06400.1 - 2.3e-23 82.4 0.5 5.6e-23 81.2 0.4 1.6 1 0 0 1 1 1 1 T5orf172 domain ABC_tran PF00005.22 EDN06401.1 - 2.2e-33 115.4 0.0 3.3e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EDN06401.1 - 1.1e-06 27.9 0.7 5.6e-05 22.4 0.2 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EDN06401.1 - 4.8e-06 26.6 0.0 8.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EDN06401.1 - 5.7e-06 26.5 0.0 0.074 13.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EDN06401.1 - 0.00083 18.0 0.7 0.0015 17.1 0.1 1.6 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA PF00004.24 EDN06401.1 - 0.002 18.3 0.2 0.64 10.2 0.1 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EDN06401.1 - 0.0025 17.4 0.4 0.68 9.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EDN06401.1 - 0.0026 17.1 0.1 0.063 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN06401.1 - 0.0052 17.5 0.0 0.015 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDN06401.1 - 0.0058 16.7 0.3 0.12 12.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EDN06401.1 - 0.0088 15.5 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EDN06401.1 - 0.017 14.3 0.0 0.038 13.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EDN06401.1 - 0.037 13.9 0.7 0.26 11.2 0.5 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EDN06401.1 - 0.038 13.9 0.0 0.48 10.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 EDN06401.1 - 0.043 13.7 0.0 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EDN06401.1 - 0.082 12.3 0.5 3 7.1 0.1 2.2 1 1 0 2 2 2 0 AAA-like domain AAA_5 PF07728.9 EDN06401.1 - 0.14 11.8 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_membrane PF00664.18 EDN06402.1 - 1.6e-79 267.1 37.2 1.2e-45 156.0 15.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDN06402.1 - 4.9e-32 111.0 0.0 1.1e-31 109.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EDN06402.1 - 8.4e-07 28.4 0.1 0.0011 18.2 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDN06402.1 - 5.9e-05 23.1 0.2 0.012 15.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EDN06402.1 - 0.00013 21.4 0.2 0.0004 19.8 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EDN06402.1 - 0.0038 16.4 0.0 0.057 12.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EDN06402.1 - 0.0057 16.0 0.1 0.045 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 EDN06402.1 - 0.034 12.7 0.3 0.087 11.3 0.0 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_22 PF13401.1 EDN06402.1 - 0.043 13.9 0.0 0.33 11.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EDN06402.1 - 0.054 13.4 0.3 0.18 11.7 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EDN06402.1 - 0.077 13.8 0.5 0.32 11.8 0.4 2.2 1 1 0 1 1 1 0 AAA domain Pam17 PF08566.5 EDN06402.1 - 0.14 11.8 0.5 0.4 10.3 0.3 1.7 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 AAA_33 PF13671.1 EDN06402.1 - 0.16 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Serglycin PF04360.7 EDN06402.1 - 1.7 8.3 7.4 1.4 8.5 1.8 2.4 2 0 0 2 2 2 0 Serglycin Ribosomal_L39 PF00832.15 EDN06404.1 - 1.3e-22 79.0 9.0 1.4e-22 78.8 6.3 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Selenoprotein_S PF06936.6 EDN06404.1 - 0.11 11.9 0.7 0.13 11.7 0.5 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Skp1 PF01466.14 EDN06405.1 - 9.3e-39 131.3 2.2 1.4e-38 130.7 1.5 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EDN06405.1 - 8.8e-12 44.9 0.1 2.2e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 EDN06405.1 - 0.11 12.5 0.1 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4375) Glyco_transf_22 PF03901.12 EDN06406.1 - 1.5e-23 83.5 16.2 1.2e-13 50.8 4.0 3.1 2 1 1 3 3 3 3 Alg9-like mannosyltransferase family DUF3488 PF11992.3 EDN06406.1 - 0.41 9.2 5.6 0.33 9.5 2.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3488) p450 PF00067.17 EDN06407.1 - 3.3e-57 194.0 0.0 1.3e-56 192.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Sybindin PF04099.7 EDN06408.1 - 2.9e-27 95.1 0.0 3.6e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EDN06408.1 - 0.00052 19.8 0.1 0.00078 19.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.20 EDN06409.1 - 2.4e-48 164.5 0.0 4e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06409.1 - 5.5e-30 104.2 0.0 9.5e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN06409.1 - 2.4e-08 33.2 0.0 1.4e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDN06409.1 - 0.012 15.4 0.2 0.029 14.1 0.2 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_23 PF13489.1 EDN06411.1 - 1.4e-15 57.3 0.0 4.4e-15 55.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN06411.1 - 1.3e-08 34.5 0.0 7.7e-08 32.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN06411.1 - 2.8e-08 34.3 0.1 1.8e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN06411.1 - 1.3e-05 25.5 0.0 0.0001 22.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EDN06411.1 - 0.00037 19.6 0.0 0.00061 18.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EDN06411.1 - 0.026 13.8 0.0 0.078 12.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.7 EDN06411.1 - 0.033 14.6 0.0 0.095 13.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PhyH PF05721.8 EDN06412.1 - 1.7e-10 41.2 0.0 1.8e-09 37.9 0.0 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Cupin_2 PF07883.6 EDN06412.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Brix PF04427.13 EDN06413.1 - 7.2e-15 55.1 0.1 8.2e-15 54.9 0.1 1.0 1 0 0 1 1 1 1 Brix domain Pinin_SDK_N PF04697.8 EDN06413.1 - 0.032 14.2 0.1 0.037 14.0 0.1 1.1 1 0 0 1 1 1 0 pinin/SDK conserved region tRNA-synt_2b PF00587.20 EDN06414.1 - 1.6e-55 187.3 0.1 2.4e-55 186.7 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDN06414.1 - 3.9e-20 71.6 1.6 1.2e-19 70.0 0.0 2.8 3 1 0 3 3 3 1 Anticodon binding domain Pkinase PF00069.20 EDN06416.1 - 2.1e-70 236.8 0.0 4.4e-70 235.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06416.1 - 4.5e-52 176.6 0.0 8.4e-52 175.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH_11 PF15413.1 EDN06416.1 - 5.3e-30 103.9 0.5 1.4e-29 102.6 0.3 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PBD PF00786.23 EDN06416.1 - 1.2e-20 73.7 0.1 1.2e-19 70.4 0.0 2.7 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EDN06416.1 - 1.8e-06 27.1 0.0 3.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 EDN06416.1 - 9.8e-06 25.7 0.2 2.1e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 PH domain APH PF01636.18 EDN06416.1 - 0.00061 19.5 1.9 0.0057 16.4 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDN06416.1 - 0.033 13.0 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 NAD_kinase PF01513.16 EDN06417.1 - 9.1e-32 109.9 0.1 1.2e-31 109.6 0.1 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Acyltransferase PF01553.16 EDN06420.1 - 2.9e-20 72.0 0.0 5.2e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase TPR_11 PF13414.1 EDN06421.1 - 4.1e-24 84.0 21.8 2.9e-06 26.8 0.0 9.2 9 1 1 10 10 10 5 TPR repeat TPR_19 PF14559.1 EDN06421.1 - 5.3e-19 68.3 20.3 1.4e-06 28.5 0.2 9.5 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.12 EDN06421.1 - 1e-18 65.6 21.7 0.0022 17.7 0.1 10.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.23 EDN06421.1 - 2.1e-18 65.0 19.5 0.00014 21.2 0.1 8.8 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 EDN06421.1 - 3.5e-18 65.2 19.7 2.1e-05 24.3 0.1 9.4 9 2 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDN06421.1 - 1.7e-16 59.2 15.8 0.049 14.2 0.0 10.5 11 1 1 12 12 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDN06421.1 - 1.1e-11 45.0 26.8 0.0011 19.6 0.2 9.6 10 2 2 12 12 11 4 Tetratricopeptide repeat TPR_8 PF13181.1 EDN06421.1 - 7.3e-09 34.7 27.0 0.00019 20.9 0.1 9.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_6 PF13174.1 EDN06421.1 - 1.9e-07 31.1 26.5 0.15 12.6 0.0 10.7 11 0 0 11 11 10 2 Tetratricopeptide repeat Apc3 PF12895.2 EDN06421.1 - 4e-06 26.8 13.8 0.079 13.1 0.3 6.4 7 0 0 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EDN06421.1 - 7.4e-06 25.7 13.8 0.099 12.8 0.0 9.4 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDN06421.1 - 6.7e-05 22.3 31.4 0.0039 16.8 0.1 9.5 11 0 0 11 11 11 2 Tetratricopeptide repeat DNA_pack_N PF02500.10 EDN06421.1 - 0.046 13.2 0.2 0.046 13.2 0.1 2.4 3 0 0 3 3 2 0 Probable DNA packing protein, N-terminus TPR_3 PF07720.7 EDN06421.1 - 0.055 13.2 7.0 17 5.3 0.2 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat SGL PF08450.7 EDN06422.1 - 7.8e-27 94.2 0.1 3.5e-25 88.8 0.1 2.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EDN06422.1 - 0.082 12.9 0.3 0.57 10.1 0.0 2.6 3 0 0 3 3 3 0 Arylesterase Fungal_trans_2 PF11951.3 EDN06423.1 - 4.4e-05 22.2 0.2 5.8e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PBD PF00786.23 EDN06425.1 - 1.5 9.3 8.2 0.11 12.9 0.8 2.7 3 0 0 3 3 3 0 P21-Rho-binding domain Es2 PF09751.4 EDN06426.1 - 1.9e-118 396.4 4.9 2.4e-118 396.1 3.4 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 CAP_N PF01213.14 EDN06426.1 - 0.025 13.8 0.4 0.025 13.8 0.3 2.4 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal Mid1 PF12929.2 EDN06427.1 - 2.2e-150 501.1 5.2 2.6e-150 500.8 3.6 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EDN06427.1 - 0.033 14.5 3.9 0.51 10.7 0.4 2.3 2 0 0 2 2 2 0 Fz domain Kin17_mid PF10357.4 EDN06428.1 - 9.2e-52 173.9 0.3 1.9e-51 172.9 0.2 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EDN06428.1 - 0.00047 20.2 1.6 0.001 19.1 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDN06428.1 - 0.00052 20.1 2.5 0.001 19.1 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EDN06428.1 - 0.0078 16.2 2.5 0.009 16.1 0.2 2.0 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) IER PF05760.7 EDN06428.1 - 4.4 7.1 15.9 6.5 6.5 11.0 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) CorA PF01544.13 EDN06429.1 - 6.1e-41 140.3 0.0 1.8e-40 138.8 0.0 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein PI31_Prot_N PF11566.3 EDN06432.1 - 0.13 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal zf-rbx1 PF12678.2 EDN06433.1 - 2.7e-24 85.0 4.8 3.4e-24 84.7 3.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EDN06433.1 - 5.5e-10 38.9 4.2 8.4e-10 38.3 2.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EDN06433.1 - 0.011 15.5 4.0 0.047 13.5 2.8 1.9 1 1 0 1 1 1 0 Ring finger domain SPC12 PF06645.8 EDN06434.1 - 6.3e-28 96.4 0.1 7.4e-28 96.1 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF4199 PF13858.1 EDN06434.1 - 0.16 11.8 1.3 0.21 11.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) APH PF01636.18 EDN06435.1 - 7.4e-05 22.5 0.2 0.0013 18.4 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EDN06435.1 - 0.031 13.4 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF1679 PF07914.6 EDN06435.1 - 0.076 11.6 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) SMI1_KNR4 PF09346.5 EDN06437.1 - 2.4e-18 66.4 0.0 9.2e-18 64.5 0.0 1.8 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Dicty_REP PF05086.7 EDN06437.1 - 0.26 8.9 6.6 0.34 8.5 4.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AJAP1_PANP_C PF15298.1 EDN06437.1 - 0.66 9.8 9.5 1.8 8.3 6.6 1.7 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Thioredoxin PF00085.15 EDN06439.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin UAA PF08449.6 EDN06441.1 - 5.2e-10 38.7 13.7 6.7e-10 38.3 9.5 1.0 1 0 0 1 1 1 1 UAA transporter family DUF2431 PF10354.4 EDN06442.1 - 9.4e-41 139.5 0.0 4e-28 98.4 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF2431) CLTH PF10607.4 EDN06443.1 - 4.6e-35 120.4 0.0 9.1e-35 119.4 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EDN06443.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 LisH COX16 PF14138.1 EDN06443.1 - 0.098 12.8 0.9 0.22 11.7 0.6 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 TruB_N PF01509.13 EDN06444.1 - 1.8e-21 76.8 0.2 1.6e-18 67.2 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EDN06444.1 - 5.3e-20 70.9 1.2 9.7e-20 70.0 0.9 1.5 1 0 0 1 1 1 1 PUA domain DER1 PF04511.10 EDN06445.1 - 5.2e-23 81.5 2.5 6.7e-23 81.2 1.7 1.1 1 0 0 1 1 1 1 Der1-like family MaoC_dehydratas PF01575.14 EDN06446.1 - 2.4e-05 23.6 0.1 5.6e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 MaoC like domain PDT PF00800.13 EDN06447.1 - 2.4e-59 199.9 0.0 3.3e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EDN06447.1 - 1.8e-05 24.0 0.0 5.3e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EDN06447.1 - 0.16 11.8 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 ACT domain eRF1_2 PF03464.10 EDN06448.1 - 2e-47 160.8 0.1 3.3e-47 160.1 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EDN06448.1 - 1.5e-39 134.7 0.2 3.2e-39 133.6 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EDN06448.1 - 3e-28 98.0 0.0 5.5e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 YbjQ_1 PF01906.12 EDN06449.1 - 6e-25 87.6 0.0 8e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding Aa_trans PF01490.13 EDN06450.1 - 2.2e-47 161.4 31.6 3.6e-27 94.8 9.3 2.3 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein DUF3068 PF11271.3 EDN06450.1 - 4.8 6.1 4.8 7.8 5.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3068) DUF3321 PF11968.3 EDN06451.1 - 6.5e-100 333.2 0.0 7.5e-100 333.0 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EDN06451.1 - 0.0097 15.6 0.0 0.019 14.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ribosomal_L23eN PF03939.8 EDN06452.1 - 9.6e-23 79.9 13.5 3.1e-22 78.3 9.4 1.9 1 1 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EDN06452.1 - 1.2e-14 53.9 4.9 1.4e-14 53.8 2.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 PHA-1 PF06542.6 EDN06452.1 - 0.058 12.0 0.6 0.077 11.6 0.4 1.1 1 0 0 1 1 1 0 Regulator protein PHA-1 zf-Tim10_DDP PF02953.10 EDN06453.1 - 1.1e-22 79.0 1.0 1.3e-22 78.8 0.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger G10 PF01125.12 EDN06454.1 - 4.1e-39 133.4 0.3 4.4e-39 133.3 0.2 1.0 1 0 0 1 1 1 1 G10 protein DegS PF05384.6 EDN06455.1 - 0.02 14.1 0.1 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Sensor protein DegS NTR2 PF15458.1 EDN06455.1 - 0.061 12.5 0.3 0.075 12.2 0.2 1.2 1 0 0 1 1 1 0 Nineteen complex-related protein 2 DUF61 PF01886.11 EDN06455.1 - 0.13 12.1 0.8 0.23 11.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF61 BTB PF00651.26 EDN06456.1 - 2.8e-05 24.0 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PT PF04886.7 EDN06456.1 - 3.2e-05 23.1 28.5 2.6e+02 1.0 19.7 2.5 1 1 0 1 1 1 0 PT repeat Pkinase PF00069.20 EDN06458.1 - 1.4e-20 73.5 0.0 6e-20 71.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06458.1 - 1e-11 44.4 0.1 0.001 18.1 0.0 3.7 4 0 0 4 4 4 3 Protein tyrosine kinase Kdo PF06293.9 EDN06458.1 - 0.00046 19.3 0.0 0.085 11.9 0.0 2.4 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-binding PF00249.26 EDN06461.1 - 1.4e-09 37.8 0.0 3.1e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN06461.1 - 4.5e-06 26.6 0.1 1.8e-05 24.7 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-C2H2_4 PF13894.1 EDN06461.1 - 5.8e-05 23.1 6.7 0.017 15.4 0.3 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN06461.1 - 0.00041 20.5 3.7 0.34 11.3 0.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type RasGEF PF00617.14 EDN06462.1 - 0.019 14.6 0.1 6.8 6.3 0.0 2.7 3 0 0 3 3 3 0 RasGEF domain RVT_1 PF00078.22 EDN06463.1 - 4.8e-29 101.2 0.0 9.2e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN06463.1 - 1.2e-18 66.8 0.1 4.2e-18 65.0 0.1 2.1 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN06463.1 - 7.3e-18 65.1 0.0 2e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EDN06463.1 - 9.6e-08 32.2 0.2 2e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_3 PF13456.1 EDN06463.1 - 0.00017 21.2 0.1 0.00049 19.8 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like zf-CCHC PF00098.18 EDN06463.1 - 0.016 15.1 4.9 0.051 13.5 3.4 1.9 1 0 0 1 1 1 0 Zinc knuckle PuR_N PF09182.5 EDN06463.1 - 0.1 12.2 0.0 0.35 10.5 0.0 1.9 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal RVT_1 PF00078.22 EDN06465.1 - 2.7e-30 105.3 0.0 6e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN06465.1 - 6.6e-22 77.3 0.1 1.9e-21 75.8 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN06465.1 - 4.6e-16 59.3 0.3 1.5e-15 57.6 0.0 2.2 2 0 0 2 2 2 1 RNase H Exo_endo_phos PF03372.18 EDN06465.1 - 8.2e-07 29.2 0.3 1.6e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HALZ PF02183.13 EDN06465.1 - 5.3e-05 22.8 1.3 0.00012 21.7 0.9 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper ATG16 PF08614.6 EDN06465.1 - 0.015 15.1 1.3 0.057 13.2 0.9 2.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 EDN06465.1 - 0.052 13.8 0.2 0.18 12.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Kinesin-relat_1 PF12711.2 EDN06465.1 - 0.064 13.6 0.3 0.2 12.0 0.2 1.8 1 0 0 1 1 1 0 Kinesin motor TSC22 PF01166.13 EDN06465.1 - 0.4 10.6 1.6 1 9.3 0.1 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family Tegument_dsDNA PF12818.2 EDN06466.1 - 0.075 11.8 0.0 0.081 11.7 0.0 1.0 1 0 0 1 1 1 0 dsDNA viral tegument protein Acetyltransf_1 PF00583.19 EDN06466.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AAA PF00004.24 EDN06467.1 - 0.00067 19.8 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EDN06467.1 - 0.001 18.5 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN06467.1 - 0.0018 17.9 0.4 0.0031 17.2 0.3 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EDN06467.1 - 0.0093 16.7 0.0 0.015 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EDN06467.1 - 0.016 14.6 0.3 0.024 14.0 0.2 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EDN06467.1 - 0.024 14.9 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EDN06467.1 - 0.032 14.1 0.0 0.073 13.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EDN06467.1 - 0.071 12.6 0.0 0.071 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EDN06467.1 - 0.13 11.5 0.2 0.18 10.9 0.2 1.2 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.7 EDN06467.1 - 0.13 11.3 0.2 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EDN06467.1 - 0.15 11.6 0.2 0.23 11.0 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EDN06467.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain TIP49 PF06068.8 EDN06467.1 - 0.18 10.4 0.1 0.25 10.0 0.1 1.1 1 0 0 1 1 1 0 TIP49 C-terminus Lac_bphage_repr PF06543.7 EDN06468.1 - 0.096 12.2 1.2 0.24 10.9 0.8 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor ClpB_D2-small PF10431.4 EDN06469.1 - 0.16 11.8 0.0 9.3 6.2 0.0 2.3 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EDN06472.1 - 2.5e-05 24.4 0.0 5.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SET_assoc PF11767.3 EDN06472.1 - 0.02 14.2 0.0 0.057 12.7 0.0 1.7 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated DivIC PF04977.10 EDN06472.1 - 0.11 12.0 0.2 0.62 9.5 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator SurA_N_3 PF13624.1 EDN06473.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain DUF3435 PF11917.3 EDN06474.1 - 1.2e-162 541.4 0.5 1.6e-162 541.0 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EDN06474.1 - 4.9e-06 26.3 0.1 0.00067 19.3 0.0 2.5 2 0 0 2 2 2 2 Phage integrase family DUF3435 PF11917.3 EDN06475.1 - 1.4e-148 495.1 0.0 1.9e-148 494.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF3723 PF12520.3 EDN06477.1 - 1.6e-179 597.6 0.0 1.6e-179 597.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3723) DUF1480 PF07351.8 EDN06478.1 - 0.1 12.5 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) APH PF01636.18 EDN06479.1 - 2.1e-08 34.1 1.5 4.8e-08 33.0 1.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN06479.1 - 0.0039 16.7 0.3 0.02 14.4 0.0 2.3 3 0 0 3 3 3 1 Choline/ethanolamine kinase Ecl1 PF12855.2 EDN06480.1 - 0.0013 17.9 3.1 0.0018 17.5 0.7 2.1 2 0 0 2 2 2 1 Life-span regulatory factor RasGEF PF00617.14 EDN06481.1 - 0.014 15.1 0.0 0.066 12.9 0.0 2.1 2 1 0 2 2 2 0 RasGEF domain HTH_12 PF08461.5 EDN06481.1 - 0.078 12.7 0.1 0.81 9.4 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain Pkinase_Tyr PF07714.12 EDN06483.1 - 3.4e-17 62.3 0.1 1.4e-07 30.8 0.0 3.9 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EDN06483.1 - 1.1e-12 47.6 0.0 3.8e-08 32.8 0.0 3.3 1 1 2 3 3 3 2 Protein kinase domain YrbL-PhoP_reg PF10707.4 EDN06483.1 - 0.022 14.0 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL AAA PF00004.24 EDN06485.1 - 3.1e-17 63.0 0.0 6e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDN06485.1 - 1.8e-06 28.8 0.0 5.3e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN06485.1 - 6.4e-05 23.0 0.5 0.00021 21.3 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EDN06485.1 - 6.9e-05 22.6 0.1 0.00049 19.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EDN06485.1 - 0.00015 22.0 0.0 0.00036 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDN06485.1 - 0.00016 21.7 1.0 0.0017 18.4 0.1 3.0 3 1 0 3 3 2 1 AAA domain RuvB_N PF05496.7 EDN06485.1 - 0.0037 16.3 0.2 0.027 13.5 0.0 2.3 2 1 1 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EDN06485.1 - 0.007 16.1 0.2 0.03 14.0 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 EDN06485.1 - 0.016 14.3 0.0 0.06 12.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 EDN06485.1 - 0.016 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EDN06485.1 - 0.017 15.0 0.0 0.066 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EDN06485.1 - 0.039 13.9 0.0 0.096 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EDN06485.1 - 0.047 13.1 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 EDN06485.1 - 0.076 12.6 0.1 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EDN06485.1 - 0.082 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.5 EDN06485.1 - 0.089 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.16 EDN06485.1 - 0.095 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Aegerolysin PF06355.8 EDN06485.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Aegerolysin TIP49 PF06068.8 EDN06485.1 - 0.15 10.7 0.0 0.24 10.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_30 PF13604.1 EDN06485.1 - 0.17 11.4 0.1 0.91 9.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.20 EDN06487.1 - 1.1e-24 87.0 0.0 1.7e-11 43.7 0.0 3.2 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06487.1 - 5e-17 61.8 0.0 1.5e-11 43.8 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EDN06487.1 - 1.5e-08 34.6 1.3 1.1e-05 25.2 0.1 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN06487.1 - 1.2e-06 28.2 0.3 1e-05 25.2 0.0 2.4 3 0 0 3 3 3 1 Choline/ethanolamine kinase RIO1 PF01163.17 EDN06487.1 - 0.0079 15.5 0.0 3 7.1 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Kdo PF06293.9 EDN06487.1 - 0.027 13.5 0.0 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4129 PF13559.1 EDN06488.1 - 0.064 13.2 1.0 0.36 10.8 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4129) SOG2 PF10428.4 EDN06488.1 - 0.13 10.9 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Pkinase PF00069.20 EDN06493.1 - 0.00022 20.4 0.0 0.00025 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EDN06493.1 - 0.0058 15.7 0.0 0.0088 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN06493.1 - 0.012 15.3 0.2 0.037 13.7 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Myb_DNA-bind_6 PF13921.1 EDN06495.1 - 0.00073 19.5 0.1 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN06496.1 - 0.022 14.8 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain PBP1_TM PF14812.1 EDN06496.1 - 0.32 11.3 7.3 0.88 9.9 5.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AA_kinase PF00696.23 EDN06498.1 - 2.1e-39 135.5 0.2 3.6e-39 134.7 0.1 1.4 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.20 EDN06498.1 - 4e-08 32.5 0.1 9.1e-06 25.0 0.0 3.1 3 0 0 3 3 3 1 ACT domain ACT_7 PF13840.1 EDN06498.1 - 6.4e-07 28.8 0.3 0.00014 21.2 0.0 2.8 2 0 0 2 2 2 2 ACT domain SapB_1 PF05184.10 EDN06498.1 - 0.019 14.8 0.2 0.045 13.5 0.1 1.6 1 0 0 1 1 1 0 Saposin-like type B, region 1 Peptidase_C78 PF07910.8 EDN06499.1 - 4.2e-64 215.6 0.0 4.7e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C78 AAA_18 PF13238.1 EDN06500.1 - 6.1e-25 88.0 0.2 1.4e-24 86.8 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN06500.1 - 4e-14 53.4 0.6 8.8e-14 52.3 0.4 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EDN06500.1 - 0.00014 22.0 0.0 0.0003 20.9 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EDN06500.1 - 0.00043 20.2 0.0 0.0011 18.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDN06500.1 - 0.0019 18.0 0.0 0.0046 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 EDN06500.1 - 0.0033 17.2 0.0 0.014 15.2 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase NTPase_1 PF03266.10 EDN06500.1 - 0.0066 16.1 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 NTPase KTI12 PF08433.5 EDN06500.1 - 0.0067 15.6 0.0 0.015 14.5 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 EDN06500.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EDN06500.1 - 0.014 15.3 0.0 0.033 14.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.1 EDN06500.1 - 0.014 15.2 0.1 0.039 13.8 0.0 1.8 1 1 1 2 2 2 0 Cytidylate kinase-like family RNA_helicase PF00910.17 EDN06500.1 - 0.016 15.3 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 EDN06500.1 - 0.023 14.6 0.1 0.066 13.1 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain DUF2075 PF09848.4 EDN06500.1 - 0.042 12.8 0.0 0.053 12.4 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EDN06500.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.9 EDN06500.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EDN06500.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.9 EDN06500.1 - 0.15 11.8 0.1 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ham1p_like PF01725.11 EDN06501.1 - 3.8e-28 98.1 0.0 4.4e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Myosin_head PF00063.16 EDN06502.1 - 6.6e-191 635.9 4.0 5.3e-148 494.1 5.1 3.1 1 1 1 2 2 2 2 Myosin head (motor domain) DIL PF01843.14 EDN06502.1 - 2.8e-34 117.1 3.6 2.8e-34 117.1 2.5 2.2 2 0 0 2 2 1 1 DIL domain IQ PF00612.22 EDN06502.1 - 8.5e-14 49.8 28.5 5.9e-05 22.3 0.5 7.0 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_10 PF12846.2 EDN06502.1 - 0.0011 18.5 0.7 0.02 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EDN06502.1 - 0.0036 17.2 2.0 0.032 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain GAS PF13851.1 EDN06502.1 - 0.0093 15.1 27.2 0.19 10.8 7.9 2.6 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding AAA_22 PF13401.1 EDN06502.1 - 0.011 15.8 0.1 0.011 15.8 0.1 2.8 2 2 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EDN06502.1 - 0.03 14.0 0.0 0.085 12.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 EDN06502.1 - 0.044 12.9 4.9 0.062 12.4 2.8 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF2582 PF10771.4 EDN06502.1 - 0.056 13.3 0.4 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2582) Cortex-I_coil PF09304.5 EDN06502.1 - 0.22 11.5 26.6 0.14 12.2 7.4 3.2 2 1 1 3 3 3 0 Cortexillin I, coiled coil FlaC_arch PF05377.6 EDN06502.1 - 0.48 10.3 8.9 0.56 10.1 0.1 4.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 EDN06502.1 - 4.3 7.1 12.1 0.32 10.8 3.7 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DegQ PF08181.6 EDN06502.1 - 6 6.6 9.0 0.33 10.7 1.1 2.8 2 0 0 2 2 2 0 DegQ (SacQ) family NAP PF00956.13 EDN06503.1 - 1.5e-85 286.2 6.2 1.8e-85 285.9 4.3 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) P5-ATPase PF12409.3 EDN06504.1 - 1.5e-38 131.3 0.0 2.7e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 EDN06504.1 - 4.1e-29 102.1 0.0 9e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EDN06504.1 - 5.2e-17 61.6 0.0 1.5e-14 53.6 0.0 2.2 1 1 1 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.21 EDN06504.1 - 1.4e-15 58.2 0.0 1.9e-14 54.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN06504.1 - 0.035 14.0 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EDN06504.1 - 0.4 10.2 0.0 0.94 9.0 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NADH_B2 PF14813.1 EDN06505.1 - 0.084 12.5 0.1 0.085 12.5 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.20 EDN06506.1 - 8.5e-28 97.2 0.0 5.5e-15 55.2 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06506.1 - 8.9e-10 38.0 0.0 2e-07 30.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase 2-Hacid_dh_C PF02826.14 EDN06508.1 - 9.8e-52 174.6 0.0 1.6e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDN06508.1 - 2.6e-36 124.0 0.0 3.4e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EDN06508.1 - 1.7e-05 24.7 0.1 3.6e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 EDN06508.1 - 0.00024 20.4 0.0 0.0006 19.2 0.0 1.7 1 0 0 1 1 1 1 ACT domain 3HCDH_N PF02737.13 EDN06508.1 - 0.00085 19.0 5.0 2.1 7.9 0.3 4.0 3 1 1 4 4 4 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EDN06508.1 - 0.0071 16.2 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 EDN06508.1 - 0.011 15.1 0.1 0.04 13.2 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain tRNA-synt_2b PF00587.20 EDN06509.1 - 1.4e-22 80.0 0.1 3.7e-22 78.7 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EDN06509.1 - 3.1e-09 36.8 15.0 3.1e-09 36.8 10.4 2.7 2 1 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF4375 PF14300.1 EDN06509.1 - 0.35 10.8 6.0 0.65 9.9 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) PFL PF02901.10 EDN06510.1 - 0.0017 16.8 0.9 0.0026 16.2 0.6 1.2 1 0 0 1 1 1 1 Pyruvate formate lyase NeuB PF03102.9 EDN06510.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 NeuB family AF1Q PF15017.1 EDN06510.1 - 0.28 11.1 0.1 0.28 11.1 0.1 2.1 1 1 1 2 2 2 0 Drug resistance and apoptosis regulator PSK_trans_fac PF07704.6 EDN06510.1 - 0.39 11.4 3.1 0.24 12.1 0.5 1.8 2 0 0 2 2 2 0 Rv0623-like transcription factor CbiK PF06180.6 EDN06511.1 - 0.066 12.2 0.1 0.084 11.9 0.1 1.2 1 1 0 1 1 1 0 Cobalt chelatase (CbiK) Ras PF00071.17 EDN06512.1 - 3.2e-44 150.1 0.4 3.6e-44 150.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN06512.1 - 3.5e-14 53.3 0.2 4.9e-14 52.8 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN06512.1 - 1.8e-08 33.8 0.0 2.1e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EDN06512.1 - 1.4e-06 28.2 0.0 2e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDN06512.1 - 2.6e-05 23.7 0.2 0.00049 19.5 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EDN06512.1 - 0.0042 16.3 0.0 0.0058 15.8 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF383 PF04063.9 EDN06513.1 - 0.07 12.6 0.0 0.089 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF383) WAPL PF07814.8 EDN06514.1 - 9.3e-15 54.2 0.0 1.6e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.1 EDN06515.1 - 3.5e-59 199.5 0.0 4.1e-39 133.9 0.0 2.0 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Flu_C_NS1 PF03506.8 EDN06515.1 - 0.037 13.7 0.2 0.063 13.0 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.8 EDN06516.1 - 2.1e-25 88.2 0.4 3e-25 87.7 0.3 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Effector_1 PF04518.7 EDN06516.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Effector from type III secretion system zf-C2H2_6 PF13912.1 EDN06516.1 - 0.17 11.8 0.5 0.17 11.8 0.3 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Sec23_Sec24 PF04810.10 EDN06516.1 - 0.52 9.9 3.9 5.7 6.5 0.6 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger AATase PF07247.7 EDN06517.1 - 2.1e-07 29.8 0.3 1.3e-06 27.2 0.2 1.9 1 1 0 1 1 1 1 Alcohol acetyltransferase Cnd1 PF12717.2 EDN06521.1 - 4.8e-41 140.5 5.9 7e-29 100.9 0.5 4.1 2 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EDN06521.1 - 7.7e-41 139.5 0.1 2.5e-40 137.8 0.1 1.9 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EDN06521.1 - 1.5e-13 50.8 1.5 4.9e-06 26.7 0.0 5.0 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EDN06521.1 - 4.5e-09 35.6 9.8 0.049 13.7 0.0 6.7 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EDN06521.1 - 2e-06 28.0 3.4 0.11 12.9 0.0 5.2 4 1 1 5 5 5 2 HEAT-like repeat DUF2435 PF10363.4 EDN06521.1 - 0.0022 17.8 0.3 3.2 7.7 0.0 4.5 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 EDN06521.1 - 0.0078 16.1 4.9 6.2 6.8 0.0 5.0 6 0 0 6 6 6 2 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.2 EDN06521.1 - 0.056 12.4 6.6 0.18 10.7 1.1 3.5 2 2 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain SVM_signal PF12113.3 EDN06522.1 - 2.4 8.0 6.3 4.8 7.1 4.4 1.4 1 0 0 1 1 1 0 SVM protein signal sequence zf-LITAF-like PF10601.4 EDN06522.1 - 9 6.2 7.8 14 5.5 5.4 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Fcf1 PF04900.7 EDN06523.1 - 0.56 10.3 2.4 0.86 9.7 0.4 2.1 1 1 1 2 2 2 0 Fcf1 DUF972 PF06156.8 EDN06523.1 - 2 8.7 9.0 0.71 10.2 4.3 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF972) NICE-3 PF07406.6 EDN06523.1 - 6.3 6.2 7.5 8.7 5.8 5.2 1.3 1 1 0 1 1 1 0 NICE-3 protein DUF3505 PF12013.3 EDN06524.1 - 6.9e-16 58.4 0.3 8.4e-15 54.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) DUF2630 PF10944.3 EDN06527.1 - 1.6 8.9 7.1 0.57 10.3 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) DUF3505 PF12013.3 EDN06530.1 - 0.00084 19.5 1.9 0.001 19.2 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) DUF1041 PF06292.12 EDN06530.1 - 3.5 7.8 5.6 14 5.8 0.4 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) Exo_endo_phos_2 PF14529.1 EDN06533.1 - 9.7e-17 60.6 0.0 2e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN06533.1 - 6e-05 23.0 0.0 9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PRKCSH PF07915.8 EDN06534.1 - 4.9e-16 59.2 0.2 2.5e-15 57.0 0.0 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF751 PF05421.6 EDN06535.1 - 0.26 11.6 0.1 0.26 11.6 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF751) DUF1282 PF06930.7 EDN06535.1 - 4.7 6.8 13.7 0.16 11.6 3.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1282) Sod_Cu PF00080.15 EDN06536.1 - 4.8e-15 55.9 0.0 9.1e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Microvir_J PF04726.8 EDN06536.1 - 0.21 11.5 0.7 0.42 10.5 0.5 1.5 1 0 0 1 1 1 0 Microvirus J protein Choline_kinase PF01633.15 EDN06538.1 - 3.5e-46 157.4 0.0 6.2e-45 153.3 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EDN06538.1 - 2.8e-13 50.1 0.6 5.4e-13 49.2 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Metallophos PF00149.23 EDN06539.1 - 2.8e-05 23.5 1.7 8e-05 22.1 1.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PSI PF01437.20 EDN06540.1 - 1.6e-05 24.9 8.6 2.4e-05 24.4 6.0 1.3 1 0 0 1 1 1 1 Plexin repeat DUF4219 PF13961.1 EDN06542.1 - 0.0045 16.3 0.2 0.011 15.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.18 EDN06542.1 - 1.1 9.2 4.3 2 8.4 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle peroxidase PF00141.18 EDN06544.1 - 4.9e-12 45.8 0.0 8.6e-12 45.0 0.0 1.4 1 1 0 1 1 1 1 Peroxidase DUF3505 PF12013.3 EDN06545.1 - 5.7e-39 132.7 5.9 5.7e-39 132.7 4.1 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3505) DUF2225 PF09986.4 EDN06545.1 - 0.032 13.7 0.2 0.74 9.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) YkuI_C PF10388.4 EDN06545.1 - 0.24 11.0 1.7 0.35 10.5 0.1 1.8 2 0 0 2 2 2 0 EAL-domain associated signalling protein domain Helicase_C PF00271.26 EDN06546.1 - 1.2e-15 57.0 0.1 2.8e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DDE_Tnp_1_7 PF13843.1 EDN06548.1 - 1.3e-07 31.0 0.0 1.3e-07 31.0 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DUF865 PF05906.6 EDN06550.1 - 0.49 10.0 10.6 69 3.1 0.2 5.6 2 1 3 5 5 5 0 Herpesvirus-7 repeat of unknown function (DUF865) DUF2981 PF11200.3 EDN06552.1 - 0.11 11.4 5.5 0.14 11.2 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) EndoU_bacteria PF14436.1 EDN06555.1 - 0.08 12.7 0.3 0.58 10.0 0.0 2.5 1 1 2 3 3 3 0 Bacterial EndoU nuclease DNA_pol_E_B PF04042.11 EDN06555.1 - 1.4 8.0 5.6 12 5.0 0.2 3.3 3 1 0 3 3 3 0 DNA polymerase alpha/epsilon subunit B Pkinase PF00069.20 EDN06556.1 - 1.4e-09 37.5 0.0 2.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN06556.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN06556.1 - 0.027 13.5 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.17 EDN06556.1 - 0.091 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF4658 PF15555.1 EDN06557.1 - 1.8 8.4 5.6 5 7.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4658) Tom37_C PF11801.3 EDN06557.1 - 8.2 6.2 12.6 0.1 12.4 2.0 2.5 2 1 1 3 3 3 0 Tom37 C-terminal domain Oxysterol_BP PF01237.13 EDN06560.1 - 2.8e-61 206.9 0.1 3.2e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Kinesin-relat_1 PF12711.2 EDN06560.1 - 0.0046 17.3 0.0 0.0083 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor RVT_1 PF00078.22 EDN06561.1 - 5.3e-13 48.8 0.0 8e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 EDN06563.1 - 5.7e-07 28.7 0.0 8.3e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 EDN06564.1 - 1.1e-59 201.3 0.0 1.4e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HLH PF00010.21 EDN06565.1 - 7.8e-11 41.5 1.2 2.9e-10 39.6 0.6 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Wbp11 PF09429.5 EDN06565.1 - 0.029 14.3 0.8 0.029 14.3 0.5 1.9 2 0 0 2 2 2 0 WW domain binding protein 11 SDF PF00375.13 EDN06567.1 - 4.5e-24 84.9 2.5 6.2e-24 84.4 1.8 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family CAAD PF14159.1 EDN06567.1 - 0.015 14.9 0.2 0.015 14.9 0.2 2.4 2 1 1 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF760 PF05542.6 EDN06567.1 - 0.094 12.9 0.0 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF760) MNHE PF01899.11 EDN06567.1 - 1.1 8.8 6.5 0.88 9.1 0.4 2.7 2 1 1 3 3 3 0 Na+/H+ ion antiporter subunit DUF4199 PF13858.1 EDN06567.1 - 1.5 8.7 5.5 3 7.7 3.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) UPF0052 PF01933.13 EDN06569.1 - 5.7e-29 101.3 0.0 7.4e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 DDE_1 PF03184.14 EDN06570.1 - 1.1e-06 27.9 0.0 1.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EDN06571.1 - 7.8e-37 126.5 0.0 1.2e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN06571.1 - 1.7e-05 24.5 0.0 4.9e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN06571.1 - 0.0047 16.4 0.6 0.0047 16.4 0.4 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain AIF_C PF14721.1 EDN06571.1 - 0.032 14.4 0.4 0.064 13.5 0.3 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Myb_DNA-bind_6 PF13921.1 EDN06573.1 - 4.3e-06 26.7 0.5 4.3e-06 26.7 0.4 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN06573.1 - 0.02 14.9 1.8 0.053 13.5 1.3 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF4219 PF13961.1 EDN06574.1 - 0.0071 15.7 0.2 0.016 14.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.18 EDN06574.1 - 1.8 8.6 4.3 3.1 7.9 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4400 PF14348.1 EDN06576.1 - 0.35 10.2 1.4 11 5.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Ebp2 PF05890.7 EDN06577.1 - 5e-73 245.7 8.6 7.2e-73 245.2 5.9 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 OmpH PF03938.9 EDN06577.1 - 0.15 12.0 7.0 0.27 11.1 4.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Tom37_C PF11801.3 EDN06577.1 - 5.4 6.8 8.6 3.8 7.3 2.3 2.2 2 0 0 2 2 2 0 Tom37 C-terminal domain RVT_1 PF00078.22 EDN06578.1 - 5.3e-32 110.9 0.0 6.7e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MOZART1 PF12554.3 EDN06580.1 - 0.31 10.5 1.1 8.3 5.9 0.1 2.5 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated CNH PF00780.17 EDN06582.1 - 3.4e-52 177.5 0.0 4.1e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 CNH domain RVT_2 PF07727.9 EDN06588.1 - 3e-52 177.0 0.0 4.3e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN06588.1 - 5.4e-06 26.5 0.1 2.3e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EDN06588.1 - 0.022 14.3 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain DUF4219 PF13961.1 EDN06588.1 - 0.028 13.8 1.9 0.047 13.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) Spore_coat_CotO PF14153.1 EDN06589.1 - 0.03 13.7 0.4 0.032 13.6 0.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Peptidase_S30 PF01577.11 EDN06589.1 - 0.042 13.2 2.4 0.12 11.7 1.1 1.8 2 0 0 2 2 2 0 Potyvirus P1 protease DEAD PF00270.24 EDN06590.1 - 1.6e-34 118.8 0.0 2e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.1 EDN06590.1 - 0.0074 15.3 0.0 0.014 14.4 0.0 1.4 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit RVT_1 PF00078.22 EDN06592.1 - 8.3e-28 97.2 0.0 1.1e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PRELI PF04707.9 EDN06593.1 - 2.9e-44 150.4 0.5 3.4e-44 150.1 0.3 1.1 1 0 0 1 1 1 1 PRELI-like family DUF724 PF05266.9 EDN06594.1 - 0.035 13.7 0.7 0.046 13.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Gag_p24 PF00607.15 EDN06594.1 - 0.07 12.6 0.6 0.61 9.5 0.2 2.0 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) Helicase_C PF00271.26 EDN06596.1 - 1.8e-15 56.5 0.1 4.6e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Smr PF01713.16 EDN06599.1 - 8.6e-11 41.8 0.5 2.7e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.5 EDN06599.1 - 5.6e-06 26.2 8.3 1.6e-05 24.8 5.7 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.11 EDN06599.1 - 6.5e-06 25.5 0.0 1.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 CUE domain SelR PF01641.13 EDN06600.1 - 1.4e-50 170.1 0.1 1.7e-50 169.8 0.1 1.0 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.1 EDN06600.1 - 0.007 16.2 4.4 0.042 13.6 0.2 3.1 2 1 1 3 3 3 1 Zinc-finger of mitochondrial splicing suppressor 51 GFA PF04828.9 EDN06600.1 - 0.014 15.3 0.9 1 9.3 0.0 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EDN06600.1 - 0.019 14.7 3.9 0.99 9.2 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon Ribosomal_S27e PF01667.12 EDN06600.1 - 0.068 12.7 0.1 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 DUF2296 PF10058.4 EDN06600.1 - 0.092 12.5 0.6 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Yippee-Mis18 PF03226.9 EDN06600.1 - 0.093 12.7 0.2 0.34 10.9 0.2 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_2 PF13240.1 EDN06600.1 - 0.14 11.6 1.3 13 5.3 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EDN06600.1 - 0.23 10.7 2.4 13 5.0 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 EDN06600.1 - 0.24 11.6 2.7 10 6.5 0.1 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_L37e PF01907.14 EDN06600.1 - 0.27 11.0 6.0 1.6 8.5 1.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L37e DNA_RNApol_7kD PF03604.8 EDN06600.1 - 0.92 9.0 3.4 16 5.0 0.4 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Coiled PF05710.7 EDN06600.1 - 4.9 7.6 5.8 5.2 7.6 0.5 2.2 1 1 1 2 2 2 0 Coiled coil zf-NADH-PPase PF09297.6 EDN06600.1 - 5.8 6.5 11.6 5 6.7 0.1 3.5 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain HTH_33 PF13592.1 EDN06601.1 - 1.6e-06 27.5 0.0 3.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_29 PF13551.1 EDN06601.1 - 0.0001 22.4 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EDN06601.1 - 0.0013 18.3 0.9 0.094 12.4 0.1 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EDN06601.1 - 0.0055 17.4 0.0 0.012 16.4 0.0 1.5 1 1 1 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EDN06601.1 - 0.018 14.8 0.3 0.059 13.2 0.2 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Tnp_IS630 PF01710.11 EDN06601.1 - 0.037 13.7 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Transposase HTH_28 PF13518.1 EDN06601.1 - 0.061 13.3 0.0 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain PAX PF00292.13 EDN06601.1 - 0.075 12.7 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 'Paired box' domain ArfGap PF01412.13 EDN06602.1 - 1.9e-40 137.2 2.0 2.9e-40 136.6 1.4 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Synaptobrevin PF00957.16 EDN06603.1 - 0.11 12.1 4.2 1.4 8.6 0.6 2.2 1 1 1 2 2 2 0 Synaptobrevin Myb_DNA-bind_6 PF13921.1 EDN06605.1 - 0.0034 17.4 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN06605.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Kdo PF06293.9 EDN06606.1 - 0.00026 20.1 0.1 0.00059 18.9 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN06606.1 - 0.017 14.8 5.7 0.026 14.2 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN06606.1 - 0.02 14.4 0.0 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EDN06606.1 - 0.022 14.1 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Zn_clus PF00172.13 EDN06607.1 - 5.9e-08 32.4 8.7 5.9e-08 32.4 6.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bestrophin PF01062.16 EDN06608.1 - 0.1 11.5 0.4 0.31 9.9 0.1 1.8 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel EST1_DNA_bind PF10373.4 EDN06609.1 - 0.00051 19.3 0.0 0.00089 18.5 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain YwiC PF14256.1 EDN06609.1 - 0.045 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 YwiC-like protein APH PF01636.18 EDN06610.1 - 4.4e-09 36.4 0.1 1.3e-07 31.6 0.3 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family ERM PF00769.14 EDN06612.1 - 0.00042 19.9 10.1 0.00042 19.9 7.0 1.8 2 0 0 2 2 2 1 Ezrin/radixin/moesin family IncA PF04156.9 EDN06612.1 - 0.025 14.2 11.2 0.04 13.5 7.7 1.3 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EDN06612.1 - 0.15 9.8 3.2 0.21 9.4 2.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF45 PF01863.12 EDN06612.1 - 0.37 10.5 6.2 1 9.1 4.3 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF45 Atg14 PF10186.4 EDN06612.1 - 6.2 5.6 11.2 9.4 5.0 7.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4407 PF14362.1 EDN06612.1 - 6.5 5.6 13.2 0.074 11.9 3.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ank_2 PF12796.2 EDN06613.1 - 8.9e-22 77.2 0.0 7.9e-10 38.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDN06613.1 - 3.1e-21 75.3 0.0 4e-09 36.7 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EDN06613.1 - 3.4e-19 67.6 0.0 1.1e-08 34.3 0.0 4.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EDN06613.1 - 3.4e-17 62.0 0.0 1.1e-07 31.8 0.0 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN06613.1 - 2.4e-13 48.9 0.0 3.9e-05 23.4 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat PLAC8 PF04749.12 EDN06614.1 - 2e-09 37.9 2.8 2.6e-09 37.5 1.9 1.2 1 0 0 1 1 1 1 PLAC8 family DivIC PF04977.10 EDN06615.1 - 0.00027 20.3 2.1 0.0012 18.2 0.1 2.0 2 0 0 2 2 2 1 Septum formation initiator HALZ PF02183.13 EDN06615.1 - 0.0094 15.6 3.7 0.52 10.0 0.1 2.3 2 0 0 2 2 2 2 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.7 EDN06615.1 - 0.073 12.8 4.0 0.094 12.4 2.8 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 EDN06615.1 - 0.077 10.8 0.4 0.085 10.6 0.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RICH PF05062.7 EDN06615.1 - 0.1 12.7 4.3 0.24 11.5 0.6 2.2 1 1 1 2 2 2 0 RICH domain DUF3677 PF12432.3 EDN06615.1 - 0.11 12.9 1.1 0.14 12.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) Phosducin PF02114.11 EDN06615.1 - 0.11 11.2 0.6 0.12 11.0 0.4 1.1 1 0 0 1 1 1 0 Phosducin DUF972 PF06156.8 EDN06615.1 - 0.14 12.4 3.7 4.3 7.7 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Orthopox_A5L PF06193.6 EDN06615.1 - 0.16 11.9 1.3 0.79 9.6 0.5 1.9 1 1 1 2 2 2 0 Orthopoxvirus A5L protein-like bZIP_1 PF00170.16 EDN06615.1 - 0.17 11.8 0.1 0.17 11.8 0.1 2.1 2 1 0 2 2 2 0 bZIP transcription factor CENP-H PF05837.7 EDN06615.1 - 0.85 9.8 3.8 1.8 8.7 0.1 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) IncA PF04156.9 EDN06615.1 - 1.3 8.5 4.7 2.3 7.8 3.2 1.4 1 1 0 1 1 1 0 IncA protein DUF904 PF06005.7 EDN06615.1 - 4.1 7.7 7.3 13 6.1 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) ATG16 PF08614.6 EDN06616.1 - 0.00025 20.9 1.4 0.00034 20.4 1.0 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 EDN06616.1 - 0.00072 17.4 5.0 0.00086 17.1 3.5 1.0 1 0 0 1 1 1 1 Myosin tail Macoilin PF09726.4 EDN06616.1 - 0.012 13.9 0.2 0.013 13.8 0.1 1.0 1 0 0 1 1 1 0 Transmembrane protein NEMO PF11577.3 EDN06616.1 - 0.018 14.8 5.5 0.034 13.8 0.3 3.0 2 2 0 3 3 3 0 NF-kappa-B essential modulator NEMO DivIC PF04977.10 EDN06616.1 - 0.02 14.3 2.5 0.84 9.1 0.2 2.7 2 1 1 3 3 3 0 Septum formation initiator DUF2205 PF10224.4 EDN06616.1 - 0.027 14.0 1.5 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) GTPase_Cys_C PF12631.2 EDN06616.1 - 0.1 13.0 1.1 0.19 12.1 0.7 1.5 1 0 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE SIR2 PF02146.12 EDN06616.1 - 0.11 12.2 8.8 0.014 15.1 2.6 1.8 1 1 1 2 2 2 0 Sir2 family DUF3450 PF11932.3 EDN06616.1 - 0.22 10.7 1.8 0.28 10.4 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fer4_21 PF14697.1 EDN06616.1 - 0.33 10.8 8.1 0.38 10.6 0.9 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf-CXXC PF02008.15 EDN06616.1 - 1.9 8.3 12.9 0.3 10.9 0.9 2.7 2 1 0 2 2 2 0 CXXC zinc finger domain CtIP_N PF10482.4 EDN06616.1 - 2.7 7.8 6.9 1.3 8.8 0.1 2.4 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Fer4_2 PF12797.2 EDN06616.1 - 3.7 7.6 8.6 5.6 7.0 1.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Pkinase PF00069.20 EDN06617.1 - 5e-13 48.8 0.1 1.8e-12 46.9 0.1 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06617.1 - 1.7e-07 30.5 0.0 3.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Patatin PF01734.17 EDN06618.1 - 1.2e-23 84.1 0.4 3e-23 82.8 0.3 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Ank_2 PF12796.2 EDN06618.1 - 7.3e-19 67.8 0.0 3.2e-08 33.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDN06618.1 - 6.4e-17 60.4 1.3 1.2e-07 31.2 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EDN06618.1 - 1.5e-16 60.0 0.4 1.1e-08 35.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN06618.1 - 3.7e-14 51.4 0.0 7.8e-06 25.6 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EDN06618.1 - 3.8e-11 43.1 1.5 4.8e-05 23.7 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) FAD_binding_8 PF08022.7 EDN06619.1 - 1.7e-11 43.9 0.0 4.2e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EDN06619.1 - 2e-07 31.1 10.7 2e-06 27.9 4.3 2.7 2 1 0 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EDN06619.1 - 1.1e-06 28.6 0.0 2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain SRF-TF PF00319.13 EDN06619.1 - 0.0021 17.2 0.3 0.005 16.0 0.2 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3723 PF12520.3 EDN06621.1 - 2.1e-111 372.9 0.0 7.1e-95 318.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) Med2 PF11214.3 EDN06622.1 - 0.17 11.9 3.2 0.29 11.1 2.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Lac_bphage_repr PF06543.7 EDN06623.1 - 0.0098 15.4 0.8 0.022 14.2 0.5 1.6 1 0 0 1 1 1 1 Lactococcus bacteriophage repressor SOBP PF15279.1 EDN06623.1 - 2.7 8.2 8.2 3.9 7.7 5.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein RVT_1 PF00078.22 EDN06625.1 - 1.1e-29 103.3 0.0 2.2e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN06625.1 - 2.7e-18 65.7 0.1 9.1e-18 64.0 0.1 2.0 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN06625.1 - 7.9e-18 65.0 0.0 2e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN06625.1 - 8.7e-05 22.2 0.0 0.00024 20.8 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like PuR_N PF09182.5 EDN06625.1 - 0.01 15.4 0.0 0.031 13.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal zf-CCHC PF00098.18 EDN06625.1 - 0.017 15.0 4.9 0.05 13.5 3.4 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-C3HC4 PF00097.20 EDN06626.1 - 8.6e-05 22.1 3.7 0.00022 20.8 2.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN06626.1 - 0.0025 17.4 8.9 0.0038 16.8 6.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TMF_TATA_bd PF12325.3 EDN06626.1 - 0.0041 16.8 3.0 0.0062 16.2 2.1 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 EDN06626.1 - 0.006 16.4 2.4 0.006 16.4 1.7 1.5 2 0 0 2 2 1 1 Afadin- and alpha -actinin-Binding DegS PF05384.6 EDN06626.1 - 0.0061 15.7 4.6 0.0089 15.2 3.2 1.2 1 0 0 1 1 1 1 Sensor protein DegS Med28 PF11594.3 EDN06626.1 - 0.0062 16.7 1.4 0.0093 16.1 1.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit 28 Seryl_tRNA_N PF02403.17 EDN06626.1 - 0.0083 16.1 0.7 0.016 15.2 0.5 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Fez1 PF06818.10 EDN06626.1 - 0.011 15.7 1.8 0.016 15.1 1.3 1.2 1 0 0 1 1 1 0 Fez1 IncA PF04156.9 EDN06626.1 - 0.012 15.2 1.0 0.016 14.7 0.7 1.1 1 0 0 1 1 1 0 IncA protein DUF2730 PF10805.3 EDN06626.1 - 0.013 15.2 0.7 0.019 14.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) zf-C3HC4_2 PF13923.1 EDN06626.1 - 0.014 15.3 5.6 0.042 13.8 4.0 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DivIC PF04977.10 EDN06626.1 - 0.017 14.5 3.1 0.033 13.6 2.2 1.5 1 0 0 1 1 1 0 Septum formation initiator zf-RING_5 PF14634.1 EDN06626.1 - 0.021 14.5 7.4 0.036 13.8 5.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain HALZ PF02183.13 EDN06626.1 - 0.023 14.4 2.1 0.034 13.8 0.8 1.8 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF4618 PF15397.1 EDN06626.1 - 0.04 13.2 2.7 0.054 12.8 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Tropomyosin_1 PF12718.2 EDN06626.1 - 0.04 13.7 4.4 0.056 13.2 3.1 1.2 1 0 0 1 1 1 0 Tropomyosin like Macoilin PF09726.4 EDN06626.1 - 0.044 12.0 3.6 0.055 11.7 2.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Fib_alpha PF08702.5 EDN06626.1 - 0.045 13.8 1.5 0.07 13.2 1.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HAUS5 PF14817.1 EDN06626.1 - 0.046 12.2 3.3 0.06 11.8 2.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF641 PF04859.7 EDN06626.1 - 0.05 13.3 2.0 0.082 12.6 1.4 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) CENP-Q PF13094.1 EDN06626.1 - 0.13 12.2 3.3 0.18 11.8 2.3 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit RmuC PF02646.11 EDN06626.1 - 0.14 10.9 2.8 0.18 10.5 1.9 1.1 1 0 0 1 1 1 0 RmuC family Flg_hook PF02120.11 EDN06626.1 - 0.15 11.7 0.6 0.2 11.3 0.4 1.2 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Prefoldin_2 PF01920.15 EDN06626.1 - 0.3 10.8 4.5 0.47 10.2 3.1 1.3 1 1 0 1 1 1 0 Prefoldin subunit APG6 PF04111.7 EDN06626.1 - 0.78 8.7 3.5 1 8.3 2.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-RING_2 PF13639.1 EDN06626.1 - 0.97 9.3 10.4 2 8.3 7.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C4pol PF14260.1 EDN06626.1 - 2.2 8.3 6.9 0.33 10.9 1.9 1.9 2 1 0 2 2 1 0 C4-type zinc-finger of DNA polymerase delta DUF3435 PF11917.3 EDN06627.1 - 3.9e-62 210.3 7.4 5.7e-62 209.7 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF3435 PF11917.3 EDN06630.1 - 3.9e-162 539.7 0.1 5.4e-162 539.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) RVT_2 PF07727.9 EDN06631.1 - 3e-69 232.7 0.0 4.7e-69 232.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN06631.1 - 4.3e-16 59.1 0.0 1.7e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EDN06631.1 - 1e-07 31.4 0.0 2.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.1 EDN06631.1 - 0.029 13.7 0.1 0.084 12.3 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) WD40 PF00400.27 EDN06632.1 - 1.6e-10 40.4 23.4 3.2e-05 23.6 0.0 6.0 8 0 0 8 8 8 3 WD domain, G-beta repeat RWD PF05773.17 EDN06632.1 - 0.0019 18.1 0.0 0.004 17.0 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 EDN06632.1 - 0.16 11.8 17.2 0.3 10.9 7.5 2.5 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 EDN06632.1 - 3.9 7.5 19.4 0.11 12.5 8.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rep-A_N PF04057.7 EDN06633.1 - 0.12 12.2 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain DUF624 PF04854.9 EDN06633.1 - 0.21 11.4 0.0 0.21 11.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function, DUF624 HTH_Tnp_Tc3_2 PF01498.13 EDN06634.1 - 1.2e-16 60.4 0.0 2.6e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EDN06634.1 - 1.5e-06 27.9 2.3 4.1e-06 26.6 1.6 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 EDN06634.1 - 0.016 14.7 2.3 0.024 14.1 0.0 2.5 2 0 0 2 2 2 0 Winged helix-turn helix HTH_29 PF13551.1 EDN06635.1 - 0.043 13.9 0.0 0.083 13.0 0.0 1.5 1 1 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.1 EDN06635.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Homeodomain-like domain UQ_con PF00179.21 EDN06636.1 - 6.8e-46 155.1 0.0 8e-46 154.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDN06636.1 - 1.9e-05 24.4 0.0 2.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EDN06636.1 - 0.0047 16.5 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EDN06636.1 - 0.029 14.2 0.1 0.033 14.0 0.1 1.3 1 1 0 1 1 1 0 RWD domain Ribosomal_L24e PF01246.15 EDN06637.1 - 7.4e-30 102.6 0.2 7.4e-30 102.6 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e PGA2 PF07543.7 EDN06637.1 - 5.8 6.7 10.1 0.97 9.2 3.9 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 Ribosomal_S30 PF04758.9 EDN06638.1 - 9.7e-30 102.1 7.5 1e-29 102.0 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 BLVR PF06375.6 EDN06640.1 - 0.0038 17.0 2.4 0.0044 16.8 1.7 1.0 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) Acetyltransf_1 PF00583.19 EDN06641.1 - 4.1e-08 33.1 0.0 5.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN06641.1 - 1.2e-07 31.8 0.1 1.7e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain 4HBT PF03061.17 EDN06642.1 - 3.8e-10 39.7 0.0 7.5e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily UCH PF00443.24 EDN06643.1 - 5.2e-56 189.7 0.0 6.6e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDN06643.1 - 2.7e-16 59.8 0.0 9.1e-16 58.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EDN06643.1 - 7.6e-11 41.2 0.0 1.6e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family IMD PF08397.6 EDN06643.1 - 0.0093 15.2 3.5 0.51 9.5 0.0 2.5 2 0 0 2 2 2 2 IRSp53/MIM homology domain ACCA PF03255.9 EDN06643.1 - 2.8 7.4 8.3 0.89 9.0 0.2 2.4 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ARPC4 PF05856.7 EDN06644.1 - 4.1e-75 250.8 3.8 4.6e-75 250.6 2.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) TYW3 PF02676.9 EDN06646.1 - 1.1e-64 217.3 0.0 1.4e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF2461 PF09365.5 EDN06647.1 - 1.6e-33 115.9 1.9 1.6e-33 115.9 1.3 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein (DUF2461) HNH_2 PF13391.1 EDN06651.1 - 5.1e-05 22.9 0.0 9.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Pkinase PF00069.20 EDN06652.1 - 3.9e-71 239.2 0.0 5.9e-71 238.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06652.1 - 7.5e-33 113.6 0.0 2.8e-30 105.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EDN06652.1 - 0.00082 19.1 0.0 0.012 15.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EDN06652.1 - 0.0018 17.4 0.0 0.004 16.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDN06652.1 - 0.0041 16.1 0.0 0.0087 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EDN06652.1 - 0.017 14.7 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase PhoD PF09423.5 EDN06653.1 - 3e-148 494.1 0.1 3.7e-148 493.8 0.1 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase p450 PF00067.17 EDN06654.1 - 9.8e-29 100.1 0.0 1.5e-26 92.9 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 NLPC_P60 PF00877.14 EDN06655.1 - 7.9e-12 44.9 0.0 1.3e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family Fasciclin PF02469.17 EDN06656.1 - 1.8e-39 134.6 0.0 5.3e-21 74.9 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain DAO PF01266.19 EDN06657.1 - 2.1e-19 69.6 0.0 2.6e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDN06657.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Redoxin PF08534.5 EDN06658.1 - 4.5e-41 139.8 0.0 5e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EDN06658.1 - 9.6e-12 44.6 0.0 1.3e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF957 PF06117.6 EDN06658.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) POP1 PF06978.6 EDN06659.1 - 2.7e-66 222.8 9.5 2.7e-66 222.8 6.6 2.2 2 1 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EDN06659.1 - 3.5e-30 103.7 0.2 9e-30 102.3 0.1 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain DUF1690 PF07956.6 EDN06660.1 - 9.3e-21 74.2 2.2 3.6e-14 52.9 0.0 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) K167R PF08065.7 EDN06660.1 - 0.0028 17.7 0.1 0.0028 17.7 0.1 2.1 2 1 0 2 2 2 1 K167R (NUC007) repeat HrpA_pilin PF09589.5 EDN06660.1 - 1.2 9.5 7.5 8.3 6.8 1.6 2.2 1 1 1 2 2 2 0 HrpA pilus formation protein Hexokinase_2 PF03727.11 EDN06661.1 - 3.7e-69 232.6 0.0 5.4e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EDN06661.1 - 1.4e-63 214.0 0.0 3.5e-63 212.6 0.0 1.6 1 1 0 1 1 1 1 Hexokinase Gly-zipper_Omp PF13488.1 EDN06661.1 - 0.4 10.3 5.0 5.7 6.6 1.1 2.4 2 0 0 2 2 2 0 Glycine zipper zf-C2HC5 PF06221.8 EDN06662.1 - 1.8e-21 75.6 6.7 3.3e-21 74.7 4.6 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type SelP_N PF04592.9 EDN06662.1 - 8 5.7 13.0 0.36 10.1 3.7 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF604 PF04646.7 EDN06663.1 - 2.7e-07 30.0 0.0 4.6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EDN06663.1 - 2e-05 23.9 0.0 4.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Fringe-like Serglycin PF04360.7 EDN06663.1 - 0.0088 15.7 0.1 0.0088 15.7 0.0 2.1 2 0 0 2 2 2 1 Serglycin GDI PF00996.13 EDN06664.1 - 6.1e-43 146.7 0.0 8.1e-43 146.3 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Pro_isomerase PF00160.16 EDN06665.1 - 1.1e-44 152.3 0.0 1.3e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 EDN06666.1 - 5.3e-17 61.8 0.1 1.9e-15 56.7 0.0 2.8 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06666.1 - 8.3e-08 31.6 0.0 2e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EDN06666.1 - 0.00049 20.1 0.9 0.0011 19.0 0.1 2.1 2 0 0 2 2 2 1 FHA domain Kdo PF06293.9 EDN06666.1 - 0.066 12.2 0.0 0.19 10.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EDN06667.1 - 4.2e-09 35.9 0.0 7.9e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN06667.1 - 0.017 14.8 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN06667.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DDE_1 PF03184.14 EDN06668.1 - 4.7e-08 32.4 0.3 2.6e-07 29.9 0.2 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN06668.1 - 4.7e-07 29.5 0.4 1.4e-06 28.0 0.1 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN06668.1 - 4.4e-06 26.1 1.1 6.3e-06 25.6 0.1 1.8 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_1 PF01527.15 EDN06668.1 - 0.094 12.6 0.3 0.32 10.9 0.0 2.1 3 0 0 3 3 3 0 Transposase Peptidase_A22B PF04258.8 EDN06669.1 - 1.9e-34 119.4 0.2 6.5e-34 117.7 0.2 1.8 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EDN06669.1 - 5.1e-07 29.1 3.6 1e-06 28.1 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1119) PBP1_TM PF14812.1 EDN06669.1 - 0.037 14.3 0.3 0.037 14.3 0.2 3.3 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0233 PF06781.7 EDN06669.1 - 0.06 12.9 0.0 0.38 10.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) RNase_PH PF01138.16 EDN06670.1 - 5.4e-18 65.5 3.3 1.3e-16 61.0 2.3 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_binding_6 PF08030.7 EDN06671.1 - 1.4e-17 64.0 0.0 6.3e-17 61.9 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EDN06671.1 - 8.5e-17 61.4 9.3 1.9e-16 60.2 5.1 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EDN06671.1 - 0.0099 16.4 0.0 7.3 7.2 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DGCR6 PF07324.6 EDN06673.1 - 0.0056 16.1 0.1 0.0079 15.6 0.0 1.2 1 0 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein Tetraspannin PF00335.15 EDN06674.1 - 1.6e-06 27.5 2.0 2.9e-06 26.7 1.4 1.4 1 1 0 1 1 1 1 Tetraspanin family Fungal_trans_2 PF11951.3 EDN06675.1 - 5.9e-05 21.8 3.7 8.7e-05 21.2 0.7 2.2 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN06675.1 - 0.0012 18.7 2.4 0.0019 18.0 1.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 EDN06676.1 - 1.2e-18 67.2 0.0 4.6e-17 62.0 0.0 2.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN06676.1 - 1.9e-11 44.3 0.2 4.6e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 EDN06676.1 - 0.00041 19.4 0.0 0.00072 18.6 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EDN06676.1 - 0.00042 19.1 0.1 0.00096 17.9 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDN06676.1 - 0.00096 18.6 0.0 0.0022 17.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EDN06676.1 - 0.031 14.2 0.1 0.071 13.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EDN06676.1 - 0.057 12.8 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 EDN06676.1 - 0.081 12.8 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.15 EDN06676.1 - 0.11 12.6 0.0 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 EDN06676.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.19 EDN06676.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain SRF-TF PF00319.13 EDN06677.1 - 1.6e-23 81.6 0.2 2.3e-23 81.1 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Shadoo PF14999.1 EDN06677.1 - 0.0043 16.8 5.6 0.0074 16.1 3.9 1.3 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.14 EDN06677.1 - 0.11 12.8 15.2 0.048 14.0 8.5 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Mg_trans_NIPA PF05653.9 EDN06678.1 - 4.3e-10 39.0 6.9 6.4e-07 28.6 0.8 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EDN06678.1 - 6.7e-05 22.9 1.3 6.7e-05 22.9 0.9 2.6 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EDN06678.1 - 0.021 15.0 1.1 0.021 15.0 0.8 3.0 3 0 0 3 3 3 0 Multidrug resistance efflux transporter vATP-synt_E PF01991.13 EDN06679.1 - 8.8e-55 185.0 6.2 1.1e-54 184.6 4.3 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF2564 PF10819.3 EDN06679.1 - 1 9.5 6.8 25 5.0 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2564) Metallophos_2 PF12850.2 EDN06680.1 - 3.6e-08 33.3 0.0 8.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EDN06680.1 - 2.4e-06 27.0 0.2 3e-05 23.5 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase HAD PF12710.2 EDN06682.1 - 4.2e-14 53.1 0.0 1.1e-13 51.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDN06682.1 - 1.2e-12 48.6 1.2 6.5e-11 43.0 0.8 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN06682.1 - 1.7e-11 43.8 0.0 5.5e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 EDN06682.1 - 2.5e-11 43.0 0.0 6.2e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.7 EDN06682.1 - 0.0063 16.1 0.3 0.014 14.9 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EDN06683.1 - 0.00011 21.5 0.0 0.00014 21.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SEN1_N PF12726.2 EDN06684.1 - 3.2e-231 769.3 4.6 4.3e-231 768.9 3.2 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EDN06684.1 - 2.4e-68 230.2 0.6 2.4e-68 230.2 0.4 2.2 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 EDN06684.1 - 2.1e-60 203.5 0.0 4.5e-60 202.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN06684.1 - 7.7e-10 38.3 0.1 2.5e-09 36.7 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EDN06684.1 - 2.7e-08 33.6 0.3 3.9e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 EDN06684.1 - 5.1e-08 32.5 0.3 3.3e-06 26.6 0.0 2.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 EDN06684.1 - 2.5e-07 30.4 0.1 0.033 13.6 0.0 3.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EDN06684.1 - 0.00046 20.0 0.0 0.22 11.3 0.0 3.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.18 EDN06684.1 - 0.0052 16.6 1.0 0.0052 16.6 0.7 3.4 3 0 0 3 3 3 2 Zinc knuckle AAA_25 PF13481.1 EDN06684.1 - 0.016 14.6 0.0 0.038 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EDN06684.1 - 0.049 12.5 0.0 0.091 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-CCHC_4 PF14392.1 EDN06684.1 - 0.46 10.1 16.2 0.68 9.6 0.8 3.9 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.1 EDN06684.1 - 2.3 8.0 12.4 1.6 8.5 1.1 3.0 1 1 2 3 3 3 0 Zinc knuckle Amidohydro_4 PF13147.1 EDN06686.1 - 1.2e-08 35.3 0.1 1.7e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 EDN06686.1 - 4.9e-07 29.5 0.0 9.6e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EDN06686.1 - 2.2e-05 24.2 0.0 3.8e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Lipase_GDSL PF00657.17 EDN06687.1 - 6.9e-18 65.3 0.0 8.7e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EDN06687.1 - 2.7e-05 24.3 0.1 6.4e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family YL1_C PF08265.6 EDN06687.1 - 0.13 11.7 0.6 0.35 10.4 0.1 1.9 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain LIM PF00412.17 EDN06688.1 - 5.6e-21 74.3 44.9 7.7e-13 48.2 3.0 5.1 4 1 0 4 4 4 3 LIM domain CorA PF01544.13 EDN06689.1 - 2.3e-07 30.1 0.0 4.8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RHH_3 PF12651.2 EDN06689.1 - 0.065 12.9 3.4 0.092 12.4 0.4 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix domain UPF0104 PF03706.8 EDN06689.1 - 0.098 11.9 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Med3 PF11593.3 EDN06691.1 - 6.4 5.8 9.9 9 5.4 6.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal WH1 PF00568.18 EDN06692.1 - 1.9e-28 98.4 0.0 2.9e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EDN06692.1 - 7.8e-05 22.1 1.9 0.00014 21.3 0.3 2.2 2 0 0 2 2 2 1 WH2 motif DDE_Tnp_4 PF13359.1 EDN06696.1 - 2.2e-10 40.3 0.0 4.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EDN06696.1 - 0.0005 19.6 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.1 EDN06696.1 - 0.0094 15.4 0.2 0.018 14.5 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1_2 PF13586.1 EDN06696.1 - 0.053 13.7 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1_7 PF13843.1 EDN06697.1 - 3.8e-34 118.3 0.0 6e-14 51.8 0.0 3.3 2 1 1 3 3 3 3 Transposase IS4 eIF-1a PF01176.14 EDN06699.1 - 1.3e-28 98.2 0.1 1.8e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ERCC4 PF02732.10 EDN06700.1 - 5.4e-24 84.5 0.0 1.2e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.1 EDN06700.1 - 0.0083 16.2 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.18 EDN06700.1 - 0.073 12.7 0.5 0.47 10.2 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix motif HHH_2 PF12826.2 EDN06700.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif PTCB-BRCT PF12738.2 EDN06701.1 - 1.4e-13 50.4 0.0 2.9e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EDN06701.1 - 6.8e-08 32.5 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.3 EDN06701.1 - 0.0018 17.9 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.16 EDN06701.1 - 0.0042 17.1 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain MFS_1 PF07690.11 EDN06702.1 - 7.9e-51 172.8 36.8 7.9e-51 172.8 25.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN06702.1 - 3.9e-07 29.0 28.1 3.5e-06 25.8 19.4 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3353 PF11833.3 EDN06702.1 - 0.85 9.0 9.4 3 7.2 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) OATP PF03137.15 EDN06702.1 - 6.6 4.6 17.9 0.066 11.2 0.8 3.2 2 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Evr1_Alr PF04777.8 EDN06703.1 - 1.2e-27 95.5 0.2 1.9e-27 94.9 0.1 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Methyltransf_23 PF13489.1 EDN06704.1 - 5.7e-18 65.1 0.0 8.5e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN06704.1 - 3.2e-10 40.5 0.0 6.3e-09 36.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN06704.1 - 2.2e-07 31.2 0.0 4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN06704.1 - 5.6e-07 29.9 0.0 5.2e-06 26.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN06704.1 - 5.9e-07 29.1 0.0 8.9e-06 25.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN06704.1 - 4.2e-05 23.8 0.0 9.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EDN06704.1 - 0.014 15.4 0.0 0.025 14.5 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EDN06704.1 - 0.096 11.7 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase MFS_1 PF07690.11 EDN06705.1 - 1e-15 57.3 17.1 1.9e-12 46.5 5.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily zf-LYAR PF08790.6 EDN06706.1 - 0.064 12.9 0.2 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger R3H PF01424.17 EDN06707.1 - 1.5e-10 40.6 0.0 3.3e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EDN06707.1 - 0.00016 21.5 160.4 0.042 13.8 10.5 12.1 8 2 2 10 10 10 6 NF-X1 type zinc finger PAM2 PF07145.10 EDN06707.1 - 0.031 13.7 0.0 0.07 12.6 0.0 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region K_channel_TID PF07941.6 EDN06707.1 - 1.3 9.3 16.8 0.46 10.7 5.9 3.7 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain G_glu_transpept PF01019.16 EDN06708.1 - 5.3e-157 523.3 0.1 6.2e-157 523.1 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Nup160 PF11715.3 EDN06708.1 - 0.06 11.4 0.0 0.093 10.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 HhH-GPD PF00730.20 EDN06709.1 - 6.4e-08 32.8 0.0 7.7e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein APH PF01636.18 EDN06713.1 - 0.00033 20.4 0.4 0.89 9.2 0.0 2.6 3 0 0 3 3 3 2 Phosphotransferase enzyme family Phage_Treg PF04761.7 EDN06713.1 - 0.061 13.1 0.3 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator zf-AN1 PF01428.11 EDN06713.1 - 0.27 11.1 10.9 0.63 9.9 7.6 1.6 1 0 0 1 1 1 0 AN1-like Zinc finger Fungal_trans PF04082.13 EDN06714.1 - 9.4e-23 80.4 1.4 1.5e-22 79.7 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN06714.1 - 2.5e-08 33.6 10.6 4.9e-08 32.7 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.7 EDN06714.1 - 0.0073 16.0 5.0 0.017 14.8 3.5 1.6 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Git3 PF11710.3 EDN06716.1 - 7.5e-29 100.7 15.0 1.3e-28 99.9 10.4 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EDN06716.1 - 2.2e-09 36.9 0.1 1.2e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EDN06716.1 - 1.5e-07 30.8 9.4 1.5e-07 30.8 6.5 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EDN06716.1 - 8.1e-06 24.9 13.3 1.2e-05 24.4 9.2 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor RTA1 PF04479.8 EDN06717.1 - 9.3e-42 143.0 4.9 1.3e-41 142.5 3.4 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF1109 PF06532.6 EDN06719.1 - 0.0079 15.6 0.2 0.0086 15.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1109) PDR_CDR PF06422.7 EDN06719.1 - 0.059 13.0 0.1 0.062 12.9 0.1 1.1 1 0 0 1 1 1 0 CDR ABC transporter Ctr PF04145.10 EDN06719.1 - 0.098 12.6 0.1 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Spore_YhcN_YlaJ PF09580.5 EDN06721.1 - 0.002 18.2 11.0 0.002 18.2 7.6 1.1 1 0 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) SPX PF03105.14 EDN06721.1 - 0.13 11.9 14.2 0.029 14.1 6.8 1.8 2 0 0 2 2 2 0 SPX domain Gti1_Pac2 PF09729.4 EDN06721.1 - 1.3 8.8 7.8 1.8 8.3 5.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Folate_carrier PF01770.13 EDN06721.1 - 3.5 6.0 4.8 4.1 5.8 3.3 1.0 1 0 0 1 1 1 0 Reduced folate carrier Ctr PF04145.10 EDN06721.1 - 4.3 7.3 4.8 6.7 6.7 3.3 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Pex14_N PF04695.8 EDN06721.1 - 8.1 6.4 12.6 12 5.9 8.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NAD_binding_11 PF14833.1 EDN06726.1 - 1.5e-43 147.6 5.7 6.5e-27 94.0 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EDN06726.1 - 2e-33 115.5 1.5 3.9e-33 114.5 1.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EDN06726.1 - 0.0023 17.5 0.3 0.005 16.5 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EDN06726.1 - 0.027 14.8 0.5 0.081 13.3 0.3 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.21 EDN06727.1 - 3.6e-11 42.7 0.0 5.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN06727.1 - 0.011 16.6 0.0 0.017 16.0 0.0 1.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN06728.1 - 2.2e-05 24.1 0.0 2.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FAD_binding_3 PF01494.14 EDN06729.1 - 3.9e-72 243.2 0.0 5e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EDN06729.1 - 0.055 12.2 0.0 0.33 9.7 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase Pkinase PF00069.20 EDN06730.1 - 1e-27 96.9 0.0 2e-27 96.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06730.1 - 4.5e-10 39.0 0.0 6.5e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN06730.1 - 0.00051 19.0 0.0 0.00074 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like NMT1 PF09084.6 EDN06731.1 - 6.5e-62 208.9 0.0 8.6e-62 208.5 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EDN06731.1 - 0.012 15.0 0.0 0.13 11.5 0.0 2.1 1 1 2 3 3 3 0 NMT1-like family PBP_like PF12727.2 EDN06731.1 - 0.03 13.2 0.0 1.9 7.3 0.0 2.2 2 0 0 2 2 2 0 PBP superfamily domain Abhydrolase_6 PF12697.2 EDN06732.1 - 5.5e-28 98.3 0.1 9.2e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family F_bP_aldolase PF01116.15 EDN06732.1 - 1.1e-13 50.9 0.1 1.8e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Abhydrolase_1 PF00561.15 EDN06732.1 - 5.9e-10 39.1 0.1 7.3e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN06732.1 - 2.6e-08 33.7 0.0 3.7e-08 33.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EDN06732.1 - 0.00028 20.6 0.0 0.00075 19.3 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Fer2_3 PF13085.1 EDN06733.1 - 1.1e-31 108.9 0.0 1.9e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EDN06733.1 - 9.1e-10 38.7 5.9 9.1e-10 38.7 4.1 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EDN06733.1 - 1e-08 35.0 4.4 1e-08 35.0 3.0 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EDN06733.1 - 4.9e-05 23.6 6.4 5.8e-05 23.4 1.1 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EDN06733.1 - 0.00026 21.2 3.7 0.049 13.9 0.2 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EDN06733.1 - 0.00036 20.2 6.6 0.00039 20.1 2.7 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EDN06733.1 - 0.0058 16.3 0.4 0.0058 16.3 0.3 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 EDN06733.1 - 0.0061 16.9 5.7 0.0061 16.9 3.9 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_15 PF13459.1 EDN06733.1 - 2.1 8.9 5.8 1.3 9.6 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain DPBB_1 PF03330.13 EDN06734.1 - 3.1e-08 33.4 0.4 7.8e-08 32.2 0.0 1.9 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EDN06734.1 - 0.0049 16.5 0.1 0.008 15.8 0.1 1.3 1 0 0 1 1 1 1 Barwin family ThiF PF00899.16 EDN06735.1 - 2.2e-40 137.6 0.0 3.4e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EDN06735.1 - 4e-27 93.6 0.2 7.6e-27 92.7 0.1 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EDN06735.1 - 2.3e-09 37.6 0.0 5.7e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EDN06735.1 - 0.0076 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EDN06735.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.19 EDN06735.1 - 0.038 12.8 0.7 0.066 12.0 0.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EDN06735.1 - 0.046 12.7 1.0 0.071 12.1 0.7 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 EDN06735.1 - 0.14 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding SLX9 PF15341.1 EDN06736.1 - 3.5e-35 121.0 3.1 4.8e-35 120.6 2.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 NAD_Gly3P_dh_N PF01210.18 EDN06737.1 - 5.6e-46 156.1 0.0 1.1e-45 155.2 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EDN06737.1 - 2.1e-44 150.8 0.5 3.6e-44 150.0 0.3 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SOR PF07682.6 EDN06737.1 - 0.039 12.5 0.1 0.06 11.9 0.0 1.2 1 0 0 1 1 1 0 Sulphur oxygenase reductase hDGE_amylase PF14701.1 EDN06738.1 - 4.1e-171 569.5 0.0 5.5e-171 569.1 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EDN06738.1 - 2.6e-113 378.4 0.0 3.9e-113 377.9 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EDN06738.1 - 4.1e-87 291.6 0.0 6.4e-87 291.0 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EDN06738.1 - 1e-24 86.1 0.0 2.4e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Pkinase PF00069.20 EDN06738.1 - 4.7e-13 48.8 0.0 7.4e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06738.1 - 4.7e-09 35.6 0.0 7.2e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Alpha-amylase PF00128.19 EDN06738.1 - 0.0048 16.3 0.0 0.44 9.9 0.0 2.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DUF2026 PF09641.5 EDN06738.1 - 0.19 11.0 0.0 5.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2026) DUF221 PF02714.10 EDN06739.1 - 1.2e-81 274.1 16.5 2e-81 273.3 11.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EDN06739.1 - 1.7e-39 134.8 1.5 1.7e-39 134.8 1.1 2.2 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EDN06739.1 - 2.5e-22 79.1 0.1 7.7e-22 77.6 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) Anoctamin PF04547.7 EDN06739.1 - 0.0017 17.0 2.3 0.0017 17.0 1.6 1.9 2 0 0 2 2 2 1 Calcium-activated chloride channel DAHP_synth_1 PF00793.15 EDN06740.1 - 4.7e-101 337.0 0.0 5.7e-101 336.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family AIG2_2 PF13772.1 EDN06742.1 - 2.5e-06 27.4 0.1 7.9e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 AIG2-like family Cytochrom_C1 PF02167.10 EDN06743.1 - 1.2e-80 270.3 0.0 1.5e-80 269.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrom_C PF00034.16 EDN06743.1 - 0.031 15.0 0.3 0.11 13.3 0.1 2.1 2 1 0 2 2 2 0 Cytochrome c Cytochrome_CBB3 PF13442.1 EDN06743.1 - 0.053 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III AAA PF00004.24 EDN06744.1 - 1.1e-19 70.9 0.2 1.6e-19 70.3 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EDN06744.1 - 0.02 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sec10 PF07393.6 EDN06745.1 - 1.5e-152 509.3 0.5 1.8e-152 509.0 0.3 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EDN06745.1 - 3.8e-07 29.7 0.2 9.9e-07 28.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN06745.1 - 4.6e-05 22.9 0.1 0.00011 21.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain RNase_H PF00075.19 EDN06746.1 - 1.2e-14 54.7 0.0 2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 EDN06746.1 - 1.4e-12 47.4 0.0 2.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CEP44 PF15007.1 EDN06747.1 - 0.056 13.1 0.2 0.063 12.9 0.2 1.1 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 WD40 PF00400.27 EDN06748.1 - 2.7e-83 271.1 23.3 1.5e-14 53.2 0.1 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EDN06748.1 - 1.1e-08 35.0 0.0 0.014 15.0 0.0 3.6 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EDN06748.1 - 1.8e-06 26.3 8.4 0.23 9.5 0.1 5.4 2 2 2 5 5 5 4 Nucleoporin Nup120/160 NLE PF08154.7 EDN06748.1 - 2.3e-06 27.4 0.1 4.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain DUF1652 PF07865.6 EDN06748.1 - 0.087 12.4 0.0 71 3.1 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1652) MutS_V PF00488.16 EDN06749.1 - 1.1e-77 260.6 0.2 1.6e-77 260.1 0.2 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EDN06749.1 - 1.8e-28 99.7 1.9 1.8e-28 99.7 1.3 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EDN06749.1 - 2.3e-10 40.4 0.1 6.9e-10 38.9 0.1 1.9 1 0 0 1 1 1 1 MutS family domain IV Epsilon_antitox PF08998.6 EDN06749.1 - 0.0055 16.6 0.2 0.017 15.0 0.2 1.8 1 0 0 1 1 1 1 Bacterial epsilon antitoxin RVT_2 PF07727.9 EDN06750.1 - 9.2e-37 126.3 0.2 8.6e-19 67.4 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN06750.1 - 4.7e-16 58.9 0.0 1.5e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EDN06750.1 - 1.2e-07 31.1 0.0 3.5e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 EDN06750.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EDN06750.1 - 0.072 12.5 0.1 0.19 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) ComC PF03047.9 EDN06751.1 - 0.079 12.3 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 COMC family RVT_2 PF07727.9 EDN06752.1 - 5.1e-37 127.1 0.1 5.1e-19 68.2 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN06752.1 - 2.3e-16 59.9 0.0 9e-16 58.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EDN06752.1 - 9.4e-08 31.5 0.0 2.1e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 EDN06752.1 - 0.0092 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EDN06752.1 - 0.034 13.5 0.1 0.12 11.8 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) UBN2_2 PF14227.1 EDN06752.1 - 0.06 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF221 PF02714.10 EDN06753.1 - 1.6e-108 362.4 25.9 2.8e-108 361.6 18.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF3779 PF12621.3 EDN06753.1 - 1e-28 99.0 1.6 1.7e-28 98.3 0.5 1.9 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EDN06753.1 - 4.5e-20 71.9 1.5 8.4e-20 71.0 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) SWIB PF02201.13 EDN06755.1 - 5.6e-20 70.8 0.1 1.1e-19 69.8 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EDN06755.1 - 1.3e-12 47.3 0.4 1.3e-12 47.3 0.2 1.9 3 0 0 3 3 3 1 DEK C terminal domain Eno-Rase_FAD_bd PF07055.7 EDN06755.1 - 0.12 12.3 0.1 9.3 6.2 0.0 2.8 2 1 0 2 2 2 0 Enoyl reductase FAD binding domain eIF2A PF08662.6 EDN06756.1 - 1.8e-38 132.2 5.5 1.7e-36 125.7 1.3 3.9 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 EDN06756.1 - 2.7e-06 26.9 0.0 6.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN06756.1 - 3.3e-06 26.8 0.0 8.7e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN06756.1 - 1.1e-05 25.3 0.0 3.1e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EDN06756.1 - 0.0002 21.0 0.1 0.078 12.8 0.0 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF1669 PF07894.7 EDN06756.1 - 0.028 13.6 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) DLH PF01738.13 EDN06757.1 - 1.7e-08 34.0 0.0 1.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family NmrA PF05368.8 EDN06758.1 - 3.6e-10 39.5 0.0 1.5e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN06758.1 - 0.00067 19.7 0.1 0.0023 17.9 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EDN06758.1 - 0.0011 18.9 0.1 0.0052 16.7 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase Velvet PF11754.3 EDN06759.1 - 1.9e-81 272.5 0.0 2.4e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Far-17a_AIG1 PF04750.9 EDN06760.1 - 7.5e-65 217.8 13.2 8.7e-65 217.6 9.2 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF3177 PF11375.3 EDN06760.1 - 0.001 18.5 1.3 0.0023 17.3 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3177) TMEM213 PF15192.1 EDN06760.1 - 0.29 11.1 1.5 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 TMEM213 family Pam17 PF08566.5 EDN06761.1 - 1e-70 236.9 0.0 1.5e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 SCP1201-deam PF14428.1 EDN06762.1 - 0.1 12.2 0.2 1.9 8.2 0.0 2.6 3 0 0 3 3 3 0 SCP1.201-like deaminase MFS_1 PF07690.11 EDN06763.1 - 1.6e-31 109.3 21.6 2.2e-31 108.8 15.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DmsC PF04976.7 EDN06763.1 - 0.0007 18.9 1.6 0.0022 17.2 0.0 2.4 2 0 0 2 2 2 1 DMSO reductase anchor subunit (DmsC) Acyl_transf_3 PF01757.17 EDN06763.1 - 0.12 11.1 20.3 0.2 10.4 8.4 2.3 2 0 0 2 2 2 0 Acyltransferase family DUF2637 PF10935.3 EDN06763.1 - 1.8 8.5 5.6 8.7 6.2 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) DDE_1 PF03184.14 EDN06765.1 - 8.5e-52 175.4 0.0 3e-51 173.6 0.0 1.9 3 0 0 3 3 3 1 DDE superfamily endonuclease DDE_Tnp_1_7 PF13843.1 EDN06766.1 - 9.6e-22 77.5 1.2 2.2e-21 76.2 0.8 1.5 1 1 0 1 1 1 1 Transposase IS4 SMP_2 PF10144.4 EDN06769.1 - 0.038 13.0 0.0 0.045 12.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin adh_short PF00106.20 EDN06770.1 - 3.1e-25 89.0 0.2 3.9e-25 88.6 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN06770.1 - 4.7e-17 62.5 0.2 5.9e-17 62.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN06770.1 - 7.3e-11 42.0 0.2 9.2e-11 41.7 0.1 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDN06770.1 - 9.4e-08 31.7 0.1 2.6e-07 30.3 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EDN06770.1 - 9.8e-06 24.6 0.0 1.1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EDN06770.1 - 3.3e-05 23.9 0.1 4e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 EDN06770.1 - 6.5e-05 22.4 0.2 0.00018 21.0 0.2 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.12 EDN06770.1 - 0.00011 21.2 0.0 0.00014 20.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain DFP PF04127.10 EDN06770.1 - 0.00081 19.0 0.1 0.0014 18.2 0.0 1.3 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 EDN06770.1 - 0.0092 15.7 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EDN06770.1 - 0.012 14.8 0.1 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family DUF1776 PF08643.5 EDN06770.1 - 0.082 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2525 PF10733.4 EDN06770.1 - 0.1 12.4 0.0 0.51 10.1 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2525) Abhydrolase_1 PF00561.15 EDN06771.1 - 2.3e-12 46.9 0.0 4.1e-12 46.1 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDN06771.1 - 1.5e-09 38.1 0.0 2.8e-09 37.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN06771.1 - 0.082 12.6 0.0 0.7 9.6 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Aminotran_4 PF01063.14 EDN06772.1 - 1.3e-20 73.8 0.0 1.6e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Cytokin_check_N PF10407.4 EDN06773.1 - 0.14 11.7 0.4 0.49 10.0 0.0 1.9 2 0 0 2 2 2 0 Cdc14 phosphatase binding protein N-terminus Pkinase PF00069.20 EDN06774.1 - 9.7e-42 142.8 0.0 1.5e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EDN06774.1 - 1.9e-40 137.6 0.0 3.4e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EDN06774.1 - 8.4e-21 74.2 0.0 4.3e-20 71.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 EDN06774.1 - 0.00058 19.2 0.1 0.078 12.5 0.0 3.0 2 0 0 2 2 2 1 PQQ enzyme repeat Kdo PF06293.9 EDN06774.1 - 0.073 12.1 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cpn60_TCP1 PF00118.19 EDN06775.1 - 1.1e-133 446.4 10.7 1.3e-133 446.1 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pro_isomerase PF00160.16 EDN06776.1 - 2.4e-50 170.7 0.1 4.6e-50 169.8 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EDN06776.1 - 8.3e-11 41.3 4.8 0.0018 18.1 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat TAS2R PF05296.8 EDN06777.1 - 0.035 12.9 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) MFS_1 PF07690.11 EDN06777.1 - 0.069 11.8 0.0 0.088 11.5 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily RCR PF12273.3 EDN06777.1 - 5.1 7.6 8.1 0.17 12.4 0.6 2.1 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red AA_permease PF00324.16 EDN06778.1 - 1.7e-61 208.0 26.6 8.6e-60 202.4 15.4 2.3 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EDN06778.1 - 2.6e-15 55.8 21.0 3.8e-15 55.3 14.6 1.1 1 0 0 1 1 1 1 Amino acid permease SPC12 PF06645.8 EDN06778.1 - 2.4 8.0 5.7 0.95 9.3 0.9 2.5 1 1 1 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) p450 PF00067.17 EDN06779.1 - 8.2e-52 176.2 0.0 1.1e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EDN06781.1 - 8.7e-38 130.0 0.0 1.2e-37 129.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MoaE PF02391.12 EDN06781.1 - 1.9e-25 88.9 0.0 2.7e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 MoaE protein DUF775 PF05603.7 EDN06783.1 - 2.4e-67 226.3 0.1 2.7e-67 226.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF1034 PF06280.7 EDN06783.1 - 0.21 11.9 2.5 1.3 9.4 0.5 2.2 1 1 1 2 2 2 0 Fn3-like domain (DUF1034) Aldedh PF00171.17 EDN06784.1 - 3.3e-119 398.2 0.0 4.1e-119 397.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glycoprotein_B PF00606.13 EDN06785.1 - 0.028 12.4 2.6 0.028 12.4 1.8 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B SUR7 PF06687.7 EDN06785.1 - 0.37 10.3 2.9 0.4 10.1 2.0 1.0 1 0 0 1 1 1 0 SUR7/PalI family Adeno_E3_CR2 PF02439.10 EDN06785.1 - 6 6.5 8.8 0.95 9.0 2.5 2.2 1 1 1 2 2 2 0 Adenovirus E3 region protein CR2 FBPase PF00316.15 EDN06792.1 - 9.2e-120 399.3 0.0 1.1e-119 399.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase FAD_binding_2 PF00890.19 EDN06793.1 - 1.5e-62 211.7 0.1 2.3e-62 211.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EDN06793.1 - 5.6e-21 74.1 0.3 2.7e-19 68.7 0.1 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EDN06793.1 - 0.00013 20.9 0.0 0.00021 20.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GDPD PF03009.12 EDN06794.1 - 2.1e-34 119.2 0.0 5.2e-34 117.9 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EDN06794.1 - 9e-05 22.5 0.0 0.00024 21.1 0.0 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF3550 PF12070.3 EDN06795.1 - 0.15 10.8 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3550/UPF0682) DUF865 PF05906.6 EDN06795.1 - 6.3 6.4 8.2 2.7 7.6 2.5 2.4 2 0 0 2 2 2 0 Herpesvirus-7 repeat of unknown function (DUF865) Zip PF02535.17 EDN06796.1 - 2.2e-59 201.0 3.9 1.4e-57 195.0 2.7 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter IGPD PF00475.13 EDN06796.1 - 5.1e-44 149.6 0.1 9.3e-44 148.7 0.0 1.4 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Anp1 PF03452.9 EDN06797.1 - 2.2e-109 364.8 0.0 2.8e-109 364.4 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EDN06797.1 - 0.0037 16.9 0.0 0.008 15.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 RVT_1 PF00078.22 EDN06798.1 - 8.5e-26 90.6 0.0 1.8e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EDN06798.1 - 5.3e-16 58.0 0.8 1.3e-15 56.7 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EDN06798.1 - 1.5e-08 34.7 0.0 4.6e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EDN06798.1 - 0.0022 17.3 0.0 0.0086 15.4 0.0 2.0 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger gag-asp_proteas PF13975.1 EDN06798.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDN06798.1 - 0.054 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.15 EDN06798.1 - 0.097 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease GFA PF04828.9 EDN06799.1 - 1.4e-19 69.8 1.2 2.7e-09 36.8 0.0 3.6 2 2 1 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme WD40 PF00400.27 EDN06800.1 - 9.5e-25 85.5 16.0 3e-09 36.3 0.4 9.4 9 0 0 9 9 9 7 WD domain, G-beta repeat HpcH_HpaI PF03328.9 EDN06803.1 - 5.6e-36 123.5 0.3 8.9e-34 116.3 0.0 2.7 2 1 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EDN06803.1 - 1.4e-11 43.8 0.1 9.6e-08 31.2 0.0 2.3 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold F-box PF00646.28 EDN06804.1 - 0.00011 21.7 0.0 0.00027 20.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN06804.1 - 0.00037 20.1 0.1 0.0013 18.3 0.0 2.0 1 0 0 1 1 1 1 F-box-like Mur_ligase_M PF08245.7 EDN06804.1 - 0.012 15.6 0.7 0.043 13.8 0.5 2.0 1 1 0 1 1 1 0 Mur ligase middle domain Ric8 PF10165.4 EDN06805.1 - 2.3e-117 392.5 0.0 2.8e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Transket_pyr PF02779.19 EDN06806.1 - 6.3e-41 139.8 0.0 9.4e-41 139.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EDN06806.1 - 3.7e-31 107.6 0.0 7.2e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain XPG_N PF00752.12 EDN06807.1 - 3.6e-35 120.2 0.0 1.3e-34 118.5 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EDN06807.1 - 1.7e-25 88.8 0.0 5.1e-25 87.3 0.0 1.9 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EDN06807.1 - 0.0033 17.6 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.15 EDN06807.1 - 0.0045 16.4 0.5 0.017 14.6 0.4 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif adh_short PF00106.20 EDN06808.1 - 3.8e-17 62.7 0.0 1.3e-16 60.9 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN06808.1 - 3e-10 40.2 0.0 3.3e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN06808.1 - 0.012 15.2 0.1 0.042 13.5 0.0 1.8 1 1 0 1 1 1 0 KR domain FlxA PF14282.1 EDN06809.1 - 0.012 15.5 3.0 0.16 11.9 2.2 2.2 2 0 0 2 2 2 0 FlxA-like protein GrpE PF01025.14 EDN06809.1 - 7.5 6.0 8.1 1.7e+02 1.6 5.6 2.1 1 1 0 1 1 1 0 GrpE RVT_1 PF00078.22 EDN06810.1 - 1.8e-18 66.7 0.0 3.6e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 EDN06810.1 - 0.068 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN06811.1 - 0.013 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain DUF1729 PF08354.5 EDN06812.1 - 0.19 11.5 0.6 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) Inhibitor_I78 PF11720.3 EDN06813.1 - 2.4e-15 56.0 0.0 2.9e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EDN06813.1 - 0.00012 22.1 0.1 0.00015 21.8 0.0 1.3 1 1 0 1 1 1 1 Potato inhibitor I family Nefa_Nip30_N PF10187.4 EDN06814.1 - 3.5e-34 117.0 12.5 3.5e-34 117.0 8.6 1.8 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2075 PF09848.4 EDN06814.1 - 0.01 14.8 1.6 0.014 14.4 1.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF2570 PF10828.3 EDN06814.1 - 0.87 9.2 5.9 1.5 8.4 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) CK_II_beta PF01214.13 EDN06815.1 - 1.2e-71 240.0 0.0 1.6e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit FAD_binding_4 PF01565.18 EDN06817.1 - 6e-22 77.6 0.1 1.5e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDN06817.1 - 4.4e-10 39.2 0.0 7.8e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Dabb PF07876.7 EDN06818.1 - 3e-14 53.2 0.1 3.2e-14 53.1 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fungal_trans_2 PF11951.3 EDN06819.1 - 3.5e-28 98.2 0.3 6.3e-28 97.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAD PF03068.10 EDN06820.1 - 4.6e-20 71.4 0.0 6e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) IglC PF11550.3 EDN06821.1 - 0.0059 15.9 0.3 0.0063 15.8 0.2 1.1 1 0 0 1 1 1 1 Intracellular growth locus C protein Abhydrolase_3 PF07859.8 EDN06822.1 - 1.1e-05 25.0 0.0 0.038 13.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDN06822.1 - 1.7e-05 24.7 0.1 6.7e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN06822.1 - 0.00077 19.2 0.0 0.0013 18.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN06822.1 - 0.0053 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3089 PF11288.3 EDN06822.1 - 0.068 12.3 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) JAB PF01398.16 EDN06823.1 - 7.8e-08 32.0 0.3 5.5e-07 29.3 0.2 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GDE_N PF12439.3 EDN06823.1 - 0.12 11.5 3.7 0.2 10.8 0.5 2.1 2 0 0 2 2 2 0 Glycogen debranching enzyme N terminal Phage_XkdX PF09693.5 EDN06823.1 - 0.24 10.9 1.2 0.35 10.4 0.2 1.7 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) HMG_box PF00505.14 EDN06825.1 - 2.6e-10 40.4 2.3 2.6e-10 40.4 1.6 3.8 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EDN06825.1 - 2.6e-09 37.3 3.6 2.6e-09 37.3 2.5 4.2 4 2 0 4 4 4 1 HMG-box domain DUF3106 PF11304.3 EDN06825.1 - 3.4 8.1 21.2 0.21 11.9 1.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) Ofd1_CTDD PF10637.4 EDN06825.1 - 3.6 6.6 7.6 1.6 7.7 3.3 1.8 2 1 0 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Helicase_C PF00271.26 EDN06826.1 - 4.7e-25 87.2 0.0 9.1e-25 86.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN06826.1 - 4.9e-13 48.9 0.0 2e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C2H2 PF00096.21 EDN06829.1 - 3.2e-18 64.8 46.5 2.5e-06 27.5 0.6 6.4 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDN06829.1 - 6.1e-17 60.9 42.8 9.8e-08 31.9 0.7 6.4 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDN06829.1 - 6.7e-14 51.1 41.3 9.1e-05 22.5 1.1 6.3 6 0 0 6 6 6 5 C2H2-type zinc finger zf-met PF12874.2 EDN06829.1 - 4.2e-10 39.4 10.4 0.0006 19.9 0.4 4.1 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDN06829.1 - 0.00015 21.7 0.1 0.00015 21.7 0.1 5.3 7 0 0 7 7 5 3 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EDN06829.1 - 0.03 14.4 16.3 0.11 12.6 2.1 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EDN06829.1 - 0.25 11.2 0.2 0.25 11.2 0.1 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EDN06829.1 - 0.38 10.8 22.9 0.47 10.5 0.6 4.1 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 EDN06829.1 - 3.5 8.0 34.0 1.2 9.4 0.1 6.1 6 1 0 6 6 6 0 C2H2-type zinc-finger domain DUF629 PF04780.7 EDN06829.1 - 8.1 4.8 10.0 7.7 4.9 0.5 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF629) GAGA PF09237.6 EDN06829.1 - 8.9 5.9 8.6 0.47 10.0 1.2 2.5 3 1 1 4 4 4 0 GAGA factor AMP-binding_C PF13193.1 EDN06830.1 - 0.0015 19.4 0.1 0.0048 17.8 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DBD_Tnp_Hermes PF10683.4 EDN06831.1 - 0.044 13.2 0.1 0.086 12.3 0.1 1.4 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain FAM163 PF15069.1 EDN06831.1 - 1.3 9.6 5.7 1.5 9.4 0.6 3.1 3 0 0 3 3 3 0 FAM163 family zf-C2H2_4 PF13894.1 EDN06832.1 - 6e-07 29.3 10.4 0.00013 22.0 1.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN06832.1 - 4.3e-06 26.7 12.1 0.00012 22.2 2.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDN06832.1 - 9.2e-06 25.7 14.5 9.6e-06 25.6 1.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 EDN06832.1 - 0.0013 18.8 8.5 0.0024 18.0 0.5 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF2225 PF09986.4 EDN06832.1 - 0.017 14.6 0.2 0.028 13.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_jaz PF12171.3 EDN06832.1 - 0.044 13.9 1.1 0.044 13.9 0.8 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EDN06832.1 - 0.048 13.7 5.1 0.088 12.9 3.5 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EDN06832.1 - 0.09 12.7 1.1 0.23 11.4 0.8 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Kelch_6 PF13964.1 EDN06833.1 - 4.1e-06 26.7 7.0 0.00071 19.6 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EDN06833.1 - 0.001 18.5 1.4 0.26 10.8 0.0 3.1 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 EDN06833.1 - 0.0016 18.3 5.6 0.27 11.2 0.1 3.9 4 0 0 4 4 4 2 Kelch motif Suf PF05843.9 EDN06835.1 - 0.026 14.2 0.3 0.042 13.5 0.2 1.4 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) YkyA PF10368.4 EDN06835.1 - 0.054 12.8 0.6 0.075 12.3 0.4 1.3 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Vint PF14623.1 EDN06838.1 - 1.3e-55 187.2 0.0 2e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 EDN06838.1 - 1.3e-29 102.1 0.0 3.2e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 EDN06838.1 - 7.2e-19 68.5 0.0 1.6e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EDN06838.1 - 2.2e-17 63.1 0.0 2.2e-14 53.4 0.0 3.8 3 1 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.23 EDN06838.1 - 5.1e-15 55.6 0.0 2.6e-14 53.3 0.0 2.1 3 0 0 3 3 3 1 von Willebrand factor type A domain Aldo_ket_red PF00248.16 EDN06839.1 - 2.5e-53 180.7 0.0 2.9e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TIM-br_sig_trns PF09370.5 EDN06840.1 - 2.3e-134 446.5 0.7 2.6e-134 446.3 0.5 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein PcrB PF01884.12 EDN06840.1 - 0.0001 21.6 3.2 0.26 10.5 0.0 3.0 2 1 1 3 3 3 2 PcrB family NMO PF03060.10 EDN06840.1 - 0.00045 19.4 1.0 0.00089 18.5 0.1 1.7 2 0 0 2 2 2 1 Nitronate monooxygenase Radical_SAM PF04055.16 EDN06840.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 1 0 1 1 1 0 Radical SAM superfamily AdoHcyase PF05221.12 EDN06841.1 - 4.1e-133 442.3 0.1 5.3e-133 442.0 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EDN06841.1 - 2.2e-84 281.2 1.8 4.2e-84 280.3 1.2 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UPF0261 PF06792.6 EDN06841.1 - 3.8e-82 275.9 0.0 5.9e-82 275.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) 2-Hacid_dh_C PF02826.14 EDN06841.1 - 2.1e-07 30.2 0.6 5.9e-07 28.7 0.1 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EDN06841.1 - 0.0017 18.0 0.2 0.0033 17.0 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 EDN06841.1 - 0.0018 17.6 0.2 0.0036 16.6 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EDN06841.1 - 0.0037 17.2 0.1 0.024 14.6 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain MFS_1 PF07690.11 EDN06842.1 - 1.2e-46 159.1 40.4 5.3e-40 137.2 18.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EDN06842.1 - 0.016 13.2 0.0 0.016 13.2 0.0 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EDN06842.1 - 3.4 5.6 20.6 0.033 12.3 4.6 2.5 2 1 0 2 2 2 0 Transmembrane secretion effector DUF2371 PF10177.4 EDN06842.1 - 5.9 6.7 8.6 5.8 6.7 2.0 3.4 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2371) Beta-lactamase PF00144.19 EDN06843.1 - 2.8e-45 154.7 0.0 4.1e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EDN06843.1 - 0.16 11.2 0.0 0.46 9.7 0.0 1.7 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase FlgD_ig PF13860.1 EDN06844.1 - 0.12 12.0 0.1 18 5.1 0.0 2.2 2 0 0 2 2 2 0 FlgD Ig-like domain zf-H2C2_2 PF13465.1 EDN06845.1 - 4.8e-08 32.8 13.0 3.2e-07 30.2 0.7 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 EDN06845.1 - 1.4e-06 28.3 5.6 8.1e-06 25.8 0.5 3.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN06845.1 - 4.5e-05 23.4 9.0 6.6e-05 22.9 0.3 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDN06845.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDN06845.1 - 0.17 12.0 0.4 0.17 12.0 0.3 3.1 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SNF2_N PF00176.18 EDN06846.1 - 8.1e-66 221.8 0.0 1.3e-65 221.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EDN06846.1 - 3e-20 71.6 1.3 3.8e-10 39.2 0.2 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 EDN06846.1 - 8.4e-20 70.8 0.5 4.4e-19 68.5 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 EDN06846.1 - 3.3e-12 46.0 0.0 9.3e-12 44.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN06846.1 - 1.3e-06 28.4 0.1 8e-05 22.5 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C2H2 PF00096.21 EDN06847.1 - 0.021 15.1 0.1 7.9 7.0 0.0 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN06847.1 - 0.11 12.9 3.7 9.7 6.7 1.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.20 EDN06848.1 - 2.9e-09 36.4 0.0 5.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06848.1 - 0.0063 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN06848.1 - 0.02 14.6 0.0 0.053 13.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Myb_DNA-bind_6 PF13921.1 EDN06849.1 - 2e-05 24.5 0.0 2.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4244 PF14029.1 EDN06849.1 - 0.083 12.0 0.2 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) ABC_tran PF00005.22 EDN06851.1 - 5.3e-35 120.6 0.0 1.3e-17 64.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EDN06851.1 - 5.6e-15 56.0 5.0 0.0003 20.8 0.0 4.3 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 EDN06851.1 - 7.2e-12 45.0 1.8 0.002 17.4 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EDN06851.1 - 1.1e-06 27.9 0.1 1.1 8.1 0.0 4.3 4 1 1 5 5 5 2 AAA ATPase domain AAA_17 PF13207.1 EDN06851.1 - 1.9e-05 25.4 0.6 0.3 11.8 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EDN06851.1 - 2.2e-05 24.6 0.0 0.01 15.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EDN06851.1 - 2.4e-05 24.5 0.0 0.034 14.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EDN06851.1 - 8.6e-05 21.9 0.4 0.065 12.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EDN06851.1 - 0.00012 21.2 0.0 0.46 9.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 VirE PF05272.6 EDN06851.1 - 0.00015 21.3 0.1 0.34 10.3 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E AAA_18 PF13238.1 EDN06851.1 - 0.00019 21.7 0.1 0.54 10.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain Rad17 PF03215.10 EDN06851.1 - 0.00026 19.8 0.0 0.059 12.0 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Miro PF08477.8 EDN06851.1 - 0.00073 20.0 0.0 0.066 13.7 0.0 2.9 3 0 0 3 3 3 1 Miro-like protein AAA_33 PF13671.1 EDN06851.1 - 0.00079 19.3 0.2 0.06 13.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EDN06851.1 - 0.0012 18.5 1.1 0.19 11.3 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EDN06851.1 - 0.0019 18.3 0.1 0.91 9.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.1 EDN06851.1 - 0.0021 18.4 0.2 0.18 12.1 0.3 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN06851.1 - 0.0021 17.4 0.1 1.7 7.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain UPF0079 PF02367.12 EDN06851.1 - 0.003 17.1 0.1 0.04 13.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 EDN06851.1 - 0.0066 15.9 3.1 0.12 11.7 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.7 EDN06851.1 - 0.0082 15.8 3.0 0.5 10.0 0.0 2.8 3 0 0 3 3 3 1 NACHT domain Thymidylate_kin PF02223.12 EDN06851.1 - 0.023 14.0 0.2 10 5.4 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase AAA_16 PF13191.1 EDN06851.1 - 0.023 14.6 0.3 7.6 6.4 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 EDN06851.1 - 0.039 12.4 0.0 0.039 12.4 0.0 2.1 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 EDN06851.1 - 0.043 13.3 2.3 0.079 12.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EDN06851.1 - 0.043 13.7 0.1 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EDN06851.1 - 0.096 12.4 0.2 6.7 6.4 0.0 2.8 2 1 1 3 3 2 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EDN06851.1 - 0.1 11.6 0.2 0.34 10.0 0.0 1.9 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.17 EDN06851.1 - 0.14 10.9 0.1 8.2 5.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.1 EDN06851.1 - 0.15 11.9 1.2 11 5.9 0.0 3.2 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EDN06851.1 - 0.2 11.1 3.5 0.9 9.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 EDN06851.1 - 0.21 11.1 0.1 5.2 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EDN06851.1 - 0.59 9.8 1.9 26 4.4 0.1 2.7 2 0 0 2 2 2 0 NTPase FF PF01846.14 EDN06852.1 - 1e-53 179.0 17.4 6.1e-15 54.8 0.7 7.1 6 1 0 6 6 6 6 FF domain WW PF00397.21 EDN06852.1 - 4e-19 68.1 11.2 3.2e-10 39.6 0.7 2.6 2 0 0 2 2 2 2 WW domain Trs65 PF12735.2 EDN06853.1 - 1.1e-73 248.2 0.1 1.6e-73 247.6 0.1 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.7 EDN06854.1 - 6.1e-23 80.2 0.1 2.7e-22 78.1 0.1 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family DAD PF02109.11 EDN06854.1 - 0.069 13.2 0.1 5.1 7.2 0.0 2.6 2 0 0 2 2 2 0 DAD family PGK PF00162.14 EDN06855.1 - 5.2e-147 489.4 0.0 5.9e-147 489.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3530 PF12048.3 EDN06855.1 - 0.2 10.5 0.0 0.36 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Dioxygenase_C PF00775.16 EDN06856.1 - 1.4e-41 141.7 0.0 1.8e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EDN06856.1 - 5.8e-11 42.2 0.0 1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Lactonase PF10282.4 EDN06857.1 - 8.6e-19 67.8 0.1 2.9e-18 66.0 0.1 1.7 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller WD40 PF00400.27 EDN06857.1 - 0.023 14.5 0.0 15 5.6 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat SGL PF08450.7 EDN06857.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region FlxA PF14282.1 EDN06858.1 - 0.0041 17.0 1.8 0.052 13.4 1.3 2.2 2 0 0 2 2 2 1 FlxA-like protein DUF1409 PF07197.7 EDN06858.1 - 2 8.5 5.7 5.4 7.1 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1409) GrpE PF01025.14 EDN06858.1 - 8.3 5.9 8.7 2.4e+02 1.1 6.0 2.1 1 1 0 1 1 1 0 GrpE rve PF00665.21 EDN06859.1 - 1.3e-16 60.7 0.1 6.7e-16 58.4 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EDN06859.1 - 2.3e-11 43.4 0.4 3.9e-10 39.4 0.0 2.6 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EDN06859.1 - 0.0033 16.8 0.1 0.0078 15.6 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Chromo PF00385.19 EDN06860.1 - 0.0046 16.6 0.1 0.0093 15.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.20 EDN06861.1 - 7.1e-09 35.1 0.0 1.3e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN06861.1 - 0.021 14.5 0.0 0.085 12.5 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN06861.1 - 0.03 13.4 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase BCS1_N PF08740.6 EDN06862.1 - 2.1e-40 138.3 0.0 3.6e-40 137.5 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN06862.1 - 4e-20 72.3 0.0 1.7e-19 70.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN06862.1 - 0.00058 19.8 0.1 0.0014 18.6 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EDN06862.1 - 0.0068 15.8 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN06862.1 - 0.015 16.0 1.5 0.1 13.3 0.0 2.9 3 1 0 3 3 3 0 AAA domain KaiC PF06745.8 EDN06862.1 - 0.025 13.7 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.1 EDN06862.1 - 0.03 14.1 0.0 0.21 11.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EDN06862.1 - 0.1 12.2 0.0 0.32 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN06862.1 - 0.14 12.2 0.0 0.39 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDN06862.1 - 0.16 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Myb_DNA-binding PF00249.26 EDN06863.1 - 4.7e-12 45.7 4.5 8.7e-09 35.2 0.1 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN06863.1 - 6.6e-08 32.5 1.0 1.8e-05 24.7 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain WRC PF08879.5 EDN06864.1 - 0.097 12.3 0.2 0.097 12.3 0.2 1.6 2 0 0 2 2 2 0 WRC DDE_1 PF03184.14 EDN06865.1 - 1.1e-50 171.7 0.0 1.8e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN06865.1 - 1.5e-07 31.3 0.0 2.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Syntaxin-6_N PF09177.6 EDN06866.1 - 0.0083 16.5 8.2 1.6 9.1 0.6 3.8 3 1 0 3 3 3 1 Syntaxin 6, N-terminal DUF16 PF01519.11 EDN06866.1 - 0.012 15.8 6.8 1.4 9.1 0.6 3.0 3 1 0 3 3 3 0 Protein of unknown function DUF16 Med9 PF07544.8 EDN06866.1 - 0.012 15.3 5.2 0.61 9.8 0.0 3.2 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 HrpB7 PF09486.5 EDN06866.1 - 0.033 14.1 8.7 2.1 8.2 0.0 4.3 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) HWE_HK PF07536.9 EDN06866.1 - 0.043 14.2 3.7 0.14 12.5 0.9 2.8 2 1 1 3 3 3 0 HWE histidine kinase Baculo_PEP_C PF04513.7 EDN06866.1 - 0.046 13.5 3.8 6.6 6.5 0.3 3.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hemerythrin PF01814.18 EDN06866.1 - 0.047 13.8 2.8 35 4.5 0.0 3.6 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain DUF3502 PF12010.3 EDN06866.1 - 0.12 12.3 0.5 6.5 6.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3502) Syntaxin PF00804.20 EDN06866.1 - 0.19 11.8 2.5 1.1 9.4 0.3 2.9 2 1 1 3 3 3 0 Syntaxin Salp15 PF12115.3 EDN06866.1 - 0.2 11.8 1.8 8.4 6.6 0.3 2.5 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation COG2 PF06148.6 EDN06866.1 - 2.2 8.1 7.0 13 5.7 1.6 3.3 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 H-kinase_dim PF02895.9 EDN06866.1 - 5 7.5 8.1 0.46 10.8 0.1 3.0 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain DUF3435 PF11917.3 EDN06867.1 - 1.2e-114 383.2 1.2 1.1e-81 274.7 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) Nipped-B_C PF12830.2 EDN06867.1 - 0.0089 15.6 1.3 1 8.9 0.1 2.3 2 0 0 2 2 2 2 Sister chromatid cohesion C-terminus zf-C2H2_4 PF13894.1 EDN06867.1 - 0.17 12.3 4.2 8.2 7.0 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN06867.1 - 0.81 10.1 5.8 4.4 7.8 0.2 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type DDE_1 PF03184.14 EDN06868.1 - 7.2e-37 126.6 0.0 1.4e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN06868.1 - 2.1e-05 24.2 0.0 6.7e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN06868.1 - 0.0061 16.0 0.6 0.0061 16.0 0.4 2.2 2 0 0 2 2 2 1 helix-turn-helix, Psq domain Pox_VP8_L4R PF04498.7 EDN06868.1 - 0.068 12.4 0.0 3.7 6.8 0.0 2.7 2 1 1 3 3 3 0 Poxvirus nucleic acid binding protein VP8/L4R TraG_N PF07916.6 EDN06868.1 - 0.98 7.7 3.8 1.5 7.2 2.7 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Borrelia_P83 PF05262.6 EDN06868.1 - 3.4 5.8 21.4 5.5 5.1 14.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2229 PF09989.4 EDN06868.1 - 3.5 7.0 8.2 30 3.9 5.6 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Abhydrolase_6 PF12697.2 EDN06869.1 - 8.7e-24 84.6 0.3 1.8e-23 83.6 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN06869.1 - 2.7e-12 46.7 0.0 1.5e-10 41.0 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN06869.1 - 3.9e-08 33.1 0.0 9.5e-08 31.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Erythro-docking PF09277.6 EDN06869.1 - 0.015 14.9 0.2 0.055 13.1 0.0 2.0 2 0 0 2 2 2 0 Erythronolide synthase, docking Esterase PF00756.15 EDN06869.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Ndr PF03096.9 EDN06869.1 - 0.031 12.7 0.0 0.07 11.6 0.0 1.6 1 1 0 1 1 1 0 Ndr family EthD PF07110.6 EDN06869.1 - 0.04 14.8 0.1 10 7.1 0.0 2.7 2 0 0 2 2 2 0 EthD domain DSS1_SEM1 PF05160.8 EDN06870.1 - 1.1e-24 85.9 16.5 1.5e-24 85.5 11.4 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Cwf_Cwc_15 PF04889.7 EDN06870.1 - 0.14 11.8 6.7 0.16 11.6 4.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Colicin-DNase PF12639.2 EDN06870.1 - 0.14 12.3 0.6 0.17 12.1 0.4 1.2 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin HTH_Tnp_Tc3_1 PF11427.3 EDN06871.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Tc3 transposase DUF3808 PF10300.4 EDN06872.1 - 4.8e-117 391.3 0.6 6.1e-117 391.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) MFS_1 PF07690.11 EDN06872.1 - 1.2e-20 73.5 25.1 7e-19 67.7 10.0 2.5 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN06872.1 - 9e-06 24.5 10.1 1.1e-05 24.2 3.1 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter Rad51 PF08423.6 EDN06873.1 - 1.5e-108 361.5 0.1 1.2e-58 198.0 0.1 2.0 1 1 1 2 2 2 2 Rad51 AAA_25 PF13481.1 EDN06873.1 - 2.9e-08 33.3 0.0 2.1e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EDN06873.1 - 1.2e-06 28.5 0.1 4e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 EDN06873.1 - 5.2e-05 22.4 0.2 0.0017 17.4 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein KaiC PF06745.8 EDN06873.1 - 0.00023 20.3 0.0 0.0004 19.5 0.0 1.4 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 EDN06873.1 - 0.0029 16.5 0.1 0.0045 15.9 0.1 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain PAXNEB PF05625.6 EDN06873.1 - 0.0049 15.7 0.3 0.027 13.2 0.0 1.9 2 0 0 2 2 2 1 PAXNEB protein Nup160 PF11715.3 EDN06874.1 - 3.5e-111 372.0 9.2 2.1e-86 290.2 1.5 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 TPR_12 PF13424.1 EDN06874.1 - 0.0075 16.1 0.9 0.18 11.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3237 PF11578.3 EDN06875.1 - 0.07 12.4 0.1 0.095 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) KAT11 PF08214.6 EDN06875.1 - 0.077 12.0 0.0 0.08 12.0 0.0 1.0 1 0 0 1 1 1 0 Histone acetylation protein Protamine_P2 PF00841.14 EDN06876.1 - 0.033 14.7 0.8 0.097 13.2 0.5 1.7 1 0 0 1 1 1 0 Sperm histone P2 CPL PF08144.6 EDN06877.1 - 4e-13 49.4 0.0 2.7e-12 46.7 0.0 2.4 3 0 0 3 3 3 1 CPL (NUC119) domain PUF PF00806.14 EDN06877.1 - 0.00063 19.0 0.1 3.1 7.4 0.0 4.0 4 0 0 4 4 4 2 Pumilio-family RNA binding repeat Ndc1_Nup PF09531.5 EDN06877.1 - 6 5.1 6.6 8.3 4.7 4.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-BED PF02892.10 EDN06881.1 - 0.26 11.0 3.4 0.097 12.4 0.3 1.8 2 0 0 2 2 2 0 BED zinc finger DNA_pol_B_palm PF14792.1 EDN06882.1 - 2.1e-31 108.2 0.0 4.3e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EDN06882.1 - 9.6e-21 73.2 0.0 2.6e-20 71.8 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EDN06882.1 - 1.4e-20 72.5 0.4 2.8e-20 71.6 0.3 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EDN06882.1 - 7.1e-18 64.5 0.3 2.8e-17 62.6 0.4 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT PF00533.21 EDN06882.1 - 0.00075 19.6 0.0 0.0022 18.1 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 EDN06882.1 - 0.0021 18.3 0.0 0.0063 16.8 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain ATP-synt_10 PF05176.9 EDN06883.1 - 9.4e-96 319.9 0.0 1.6e-95 319.1 0.0 1.3 1 1 1 2 2 2 1 ATP10 protein V-SNARE_C PF12352.3 EDN06884.1 - 1.3e-09 38.0 0.3 1.3e-09 38.0 0.2 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Het-C PF07217.6 EDN06884.1 - 0.1 10.7 2.0 0.11 10.7 0.1 1.7 1 1 1 2 2 2 0 Heterokaryon incompatibility protein Het-C eIF3_N PF09440.5 EDN06884.1 - 0.63 10.2 3.3 0.89 9.7 0.6 2.2 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain Syntaxin-6_N PF09177.6 EDN06884.1 - 1.6 9.1 9.5 0.55 10.6 1.9 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FTA4 PF13093.1 EDN06884.1 - 3.4 7.0 11.3 16 4.8 8.0 1.9 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Uds1 PF15456.1 EDN06884.1 - 4.1 7.4 12.5 0.55 10.2 3.4 2.6 1 1 1 2 2 2 0 Up-regulated During Septation IncA PF04156.9 EDN06884.1 - 7 6.2 15.2 5.8 6.4 9.5 1.5 1 1 0 1 1 1 0 IncA protein Ribosomal_L29 PF00831.18 EDN06885.1 - 1.6e-18 66.1 0.3 1.6e-18 66.1 0.2 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein Cortex-I_coil PF09304.5 EDN06885.1 - 0.31 11.1 7.3 0.039 13.9 1.3 1.9 1 1 0 2 2 2 0 Cortexillin I, coiled coil CorA PF01544.13 EDN06885.1 - 0.33 9.9 1.7 0.5 9.3 1.2 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Snapin_Pallidin PF14712.1 EDN06885.1 - 0.82 10.0 4.6 0.37 11.1 0.4 2.1 1 1 2 3 3 3 0 Snapin/Pallidin FliT PF05400.8 EDN06885.1 - 1.3 9.4 4.3 2.1 8.8 0.1 2.3 2 1 0 2 2 2 0 Flagellar protein FliT Phe_tRNA-synt_N PF02912.13 EDN06885.1 - 8.9 6.1 8.0 3.1 7.5 0.1 2.6 3 1 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain Med16 PF11635.3 EDN06886.1 - 2.1e-192 641.0 0.0 8.5e-99 331.5 0.0 2.0 1 1 1 2 2 2 2 Mediator complex subunit 16 SIR2 PF02146.12 EDN06887.1 - 3e-28 98.7 0.0 6.1e-28 97.7 0.0 1.5 1 1 0 1 1 1 1 Sir2 family CBFD_NFYB_HMF PF00808.18 EDN06888.1 - 8.3e-07 28.9 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDN06888.1 - 0.019 15.0 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Nop14 PF04147.7 EDN06888.1 - 0.41 8.5 18.0 0.65 7.8 12.5 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EDN06888.1 - 2.4 6.5 25.7 0.14 10.5 13.8 1.7 2 0 0 2 2 2 0 Daxx Family GN3L_Grn1 PF08701.6 EDN06889.1 - 4.7e-26 90.5 17.1 1.2e-25 89.2 11.8 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EDN06889.1 - 9.4e-21 73.9 0.1 2.8e-15 56.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDN06889.1 - 2.1e-06 27.6 3.6 0.12 12.2 0.0 4.0 3 1 0 4 4 4 3 Dynamin family FeoB_N PF02421.13 EDN06889.1 - 5.9e-05 22.3 0.3 0.00017 20.9 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EDN06889.1 - 6.7e-05 22.4 0.0 0.22 10.9 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EDN06889.1 - 0.00037 19.7 0.1 0.00062 18.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EDN06889.1 - 0.0058 16.9 2.6 0.0082 16.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EDN06889.1 - 0.016 15.7 0.1 1.7 9.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein ArgK PF03308.11 EDN06889.1 - 0.02 13.6 2.3 0.028 13.1 0.0 2.0 2 0 0 2 2 2 0 ArgK protein AAA_16 PF13191.1 EDN06889.1 - 0.047 13.6 1.4 0.3 11.0 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain ORC3_N PF07034.6 EDN06889.1 - 0.15 10.9 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus AAA_17 PF13207.1 EDN06889.1 - 0.24 12.2 0.1 0.24 12.2 0.0 2.7 2 1 0 2 2 1 0 AAA domain PIN_4 PF13638.1 EDN06889.1 - 0.28 11.2 1.9 0.69 10.0 1.3 1.6 1 0 0 1 1 1 0 PIN domain HAD_2 PF13419.1 EDN06890.1 - 2e-19 70.5 0.0 2.4e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDN06890.1 - 4e-14 53.5 0.0 1.8e-12 48.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN06890.1 - 3.9e-09 36.0 0.2 9.2e-09 34.8 0.0 1.6 1 1 1 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 EDN06890.1 - 1.2e-05 25.5 0.0 1.5e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EDN06890.1 - 0.015 15.1 0.1 0.13 12.1 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF1106 PF06523.6 EDN06891.1 - 0.0089 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1106) DUF2628 PF10947.3 EDN06891.1 - 0.021 14.6 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Homeobox PF00046.24 EDN06892.1 - 4e-16 58.3 2.1 1.1e-15 56.9 1.5 1.9 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EDN06892.1 - 3.6e-05 23.3 0.8 3.6e-05 23.3 0.6 2.4 2 0 0 2 2 2 1 Homeobox KN domain DUF4638 PF15472.1 EDN06892.1 - 0.05 13.1 6.7 0.087 12.4 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) CRC_subunit PF08624.5 EDN06893.1 - 4.8e-56 188.5 0.1 7.1e-56 187.9 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Sdh_cyt PF01127.17 EDN06896.1 - 3e-22 78.7 1.5 4e-22 78.3 1.1 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PepSY_TM_1 PF13172.1 EDN06896.1 - 0.018 14.7 0.3 0.063 13.0 0.2 2.0 1 0 0 1 1 1 0 PepSY-associated TM helix SLD3 PF08639.5 EDN06897.1 - 1e-156 522.5 15.6 1.9e-156 521.5 10.8 1.5 1 0 0 1 1 1 1 DNA replication regulator SLD3 NYD-SP28_assoc PF14775.1 EDN06897.1 - 0.085 12.5 0.6 0.22 11.2 0.4 1.7 1 0 0 1 1 1 0 Sperm tail C-terminal domain S-AdoMet_synt_C PF02773.11 EDN06898.1 - 3.1e-78 260.1 0.2 6.5e-78 259.1 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EDN06898.1 - 5e-46 155.5 0.0 9.6e-46 154.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EDN06898.1 - 1.3e-42 144.0 0.6 3.1e-42 142.8 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain ATP_bind_1 PF03029.12 EDN06899.1 - 5.3e-76 255.2 0.0 7.6e-76 254.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EDN06899.1 - 5.6e-06 27.1 0.0 1.7e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDN06899.1 - 0.00036 20.4 0.0 0.00063 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDN06899.1 - 0.00061 19.9 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN06899.1 - 0.00068 19.3 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 EDN06899.1 - 0.0021 18.2 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EDN06899.1 - 0.0022 17.8 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EDN06899.1 - 0.0028 17.3 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EDN06899.1 - 0.0031 17.5 0.0 0.0065 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EDN06899.1 - 0.0033 16.3 0.0 0.0061 15.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_31 PF13614.1 EDN06899.1 - 0.0048 16.8 0.0 0.0098 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EDN06899.1 - 0.007 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase SRP54 PF00448.17 EDN06899.1 - 0.011 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 EDN06899.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EDN06899.1 - 0.013 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 EDN06899.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EDN06899.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EDN06899.1 - 0.028 14.7 0.0 0.097 12.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 EDN06899.1 - 0.044 13.2 0.0 0.1 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EDN06899.1 - 0.046 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EDN06899.1 - 0.046 14.0 0.0 0.087 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDN06899.1 - 0.047 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EDN06899.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family cobW PF02492.14 EDN06899.1 - 0.079 12.3 0.1 0.41 10.0 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KaiC PF06745.8 EDN06899.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.1 EDN06899.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EDN06899.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EDN06899.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Septin FAD_binding_8 PF08022.7 EDN06900.1 - 4.4e-08 32.9 0.0 0.0025 17.6 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 EDN06900.1 - 1.3e-06 28.3 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EDN06900.1 - 2.1e-05 24.6 1.1 2.1e-05 24.6 0.8 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF2031 PF09592.5 EDN06901.1 - 0.0013 17.9 0.4 0.0013 17.9 0.3 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2031) DUF869 PF05911.6 EDN06901.1 - 0.007 14.6 42.1 0.2 9.8 7.3 3.1 1 1 1 2 2 2 2 Plant protein of unknown function (DUF869) Filament PF00038.16 EDN06901.1 - 0.29 10.5 71.4 0.4 10.1 14.1 5.4 5 0 0 5 5 5 0 Intermediate filament protein Med26 PF08711.6 EDN06903.1 - 6e-12 44.8 0.0 1.1e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CAML PF14963.1 EDN06903.1 - 1.8 7.8 9.7 3.3 6.9 6.7 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Tom5 PF10642.4 EDN06904.1 - 8.1e-24 83.0 0.2 8.7e-24 82.9 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.1 EDN06905.1 - 2.1e-46 157.0 1.8 2.1e-46 157.0 1.3 2.2 1 1 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EDN06905.1 - 1.3e-12 47.8 84.1 4e-08 33.4 20.1 3.3 1 1 2 3 3 3 2 Nucleoporin FG repeat region DUF972 PF06156.8 EDN06905.1 - 1.7 8.9 6.1 4.2 7.7 3.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) AAA PF00004.24 EDN06906.1 - 9.9e-15 54.9 0.0 2.2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN06906.1 - 2.2e-10 40.8 0.0 1.3e-09 38.3 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN06906.1 - 1.7e-08 34.7 0.0 4.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN06906.1 - 5.2e-05 22.9 0.2 0.00021 20.9 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EDN06906.1 - 0.00049 20.9 0.0 0.0036 18.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EDN06906.1 - 0.00083 18.9 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain BAH PF01426.13 EDN06906.1 - 0.0012 18.6 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 BAH domain NACHT PF05729.7 EDN06906.1 - 0.0027 17.3 0.0 0.0076 15.9 0.0 1.7 1 1 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EDN06906.1 - 0.011 15.4 0.0 0.088 12.4 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 EDN06906.1 - 0.017 15.1 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDN06906.1 - 0.022 14.6 0.0 0.087 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDN06906.1 - 0.028 14.5 0.0 0.1 12.7 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA_32 PF13654.1 EDN06906.1 - 0.04 12.5 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EDN06906.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.9 EDN06906.1 - 0.07 12.8 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EDN06906.1 - 0.084 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EDN06906.1 - 0.14 11.1 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.27 EDN06907.1 - 8.5e-54 177.6 9.7 2.9e-10 39.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EDN06907.1 - 0.0008 17.6 5.1 1.9 6.4 0.1 4.5 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EDN06907.1 - 0.016 14.6 0.3 5.6 6.3 0.0 2.6 2 1 0 2 2 2 0 PQQ-like domain Nucleoporin_N PF08801.6 EDN06907.1 - 0.037 12.7 0.0 1.2 7.8 0.0 2.4 1 1 1 2 2 2 0 Nup133 N terminal like Ank_2 PF12796.2 EDN06908.1 - 1e-39 134.7 0.3 1.9e-16 60.1 0.4 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EDN06908.1 - 2.2e-36 121.8 1.9 1.2e-05 24.8 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 EDN06908.1 - 2.6e-34 116.4 3.3 3e-10 39.9 0.4 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN06908.1 - 2.2e-31 107.6 6.0 2e-08 34.4 0.0 5.2 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN06908.1 - 2.3e-27 92.2 0.5 0.0012 18.9 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat TMF_TATA_bd PF12325.3 EDN06909.1 - 2.5e-45 153.0 12.3 2.5e-45 153.0 8.5 5.8 3 2 2 5 5 5 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EDN06909.1 - 6.9e-24 83.4 18.6 6.9e-24 83.4 12.9 8.5 6 2 3 9 9 9 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 EDN06909.1 - 0.0014 18.5 5.1 0.0014 18.5 3.5 5.2 3 1 1 5 5 5 1 Autophagy protein 16 (ATG16) DUF2443 PF10398.4 EDN06909.1 - 0.0028 17.4 3.7 0.92 9.3 0.4 3.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2443) Tropomyosin PF00261.15 EDN06909.1 - 8 5.4 97.3 0.19 10.7 33.3 5.2 3 1 1 4 4 4 0 Tropomyosin V-ATPase_H_N PF03224.9 EDN06910.1 - 3.2e-82 276.1 0.0 4.2e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EDN06910.1 - 6.1e-39 132.6 0.0 2.1e-38 130.9 0.0 1.9 2 0 0 2 2 2 1 V-ATPase subunit H Acetyltransf_1 PF00583.19 EDN06911.1 - 1.6e-06 28.0 0.1 2.4e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN06911.1 - 5.8e-06 26.3 0.0 7.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDN06911.1 - 0.00044 20.0 0.0 0.00063 19.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDN06911.1 - 0.0006 19.9 0.0 0.00077 19.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDN06911.1 - 0.027 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein RHD3 PF05879.7 EDN06912.1 - 0 1053.7 0.0 0 1053.4 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EDN06912.1 - 2.9e-07 29.8 0.1 5.1e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EDN06912.1 - 9.9e-07 28.7 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EDN06912.1 - 0.00021 21.2 0.0 0.00044 20.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EDN06912.1 - 0.0013 18.6 0.0 0.004 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EDN06912.1 - 0.0032 17.9 0.0 0.0069 16.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 EDN06912.1 - 0.089 11.7 0.0 0.22 10.4 0.0 1.7 1 0 0 1 1 1 0 Septin GTP_EFTU PF00009.22 EDN06914.1 - 2e-49 167.6 0.0 2.7e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDN06914.1 - 5.5e-25 87.4 0.1 4.9e-24 84.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDN06914.1 - 2.1e-18 66.2 1.4 4.9e-18 65.0 1.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EDN06914.1 - 0.0008 19.0 0.3 0.0027 17.3 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EDN06914.1 - 0.045 13.7 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EDN06914.1 - 0.12 11.4 0.1 0.35 9.9 0.1 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region IF3_C PF00707.17 EDN06915.1 - 3.8e-12 45.7 1.6 6.3e-12 45.0 1.1 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EDN06915.1 - 6.7e-05 22.3 2.8 0.00011 21.6 1.9 1.4 1 0 0 1 1 1 1 Mitochondrial translation initiation factor IF3_N PF05198.11 EDN06915.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain GDA1_CD39 PF01150.12 EDN06916.1 - 8.9e-99 330.9 0.0 1.2e-98 330.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Asn_synthase PF00733.16 EDN06917.1 - 7.9e-52 176.2 0.0 1.2e-51 175.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EDN06917.1 - 9.2e-37 125.5 0.0 1.5e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EDN06917.1 - 1.9e-32 112.0 0.0 4.7e-32 110.7 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EDN06917.1 - 1.9e-05 23.5 0.0 0.057 12.1 0.0 3.1 1 1 2 3 3 3 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 EDN06917.1 - 4.9e-05 22.6 0.0 9.6e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EDN06917.1 - 0.23 10.3 0.3 0.71 8.7 0.1 1.9 1 1 1 2 2 2 0 NAD synthase Sod_Fe_N PF00081.17 EDN06918.1 - 2.1e-29 101.5 3.5 4.7e-29 100.4 1.5 2.1 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 EDN06918.1 - 9e-27 92.9 2.3 1.1e-25 89.4 1.6 2.2 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain DUF4598 PF15370.1 EDN06919.1 - 2.7e-23 82.4 1.0 2.7e-23 82.4 0.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) RAP1 PF07218.6 EDN06919.1 - 3.2 5.7 7.9 3.3 5.7 5.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IF4E PF01652.13 EDN06920.1 - 2.1e-37 128.2 0.4 2.5e-37 127.9 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF2517 PF10725.4 EDN06920.1 - 0.016 14.9 0.2 5.6 6.7 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2517) COMPASS-Shg1 PF05205.7 EDN06921.1 - 6.9e-31 106.6 0.1 6.9e-31 106.6 0.1 2.2 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 Cation_efflux PF01545.16 EDN06923.1 - 2.1e-32 112.3 7.8 3.5e-32 111.6 5.4 1.2 1 0 0 1 1 1 1 Cation efflux family DUF1418 PF07214.7 EDN06923.1 - 0.11 12.0 0.9 0.76 9.4 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) GCV_H PF01597.14 EDN06925.1 - 2.1e-41 140.3 2.2 2.5e-41 140.1 1.5 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein FTR_C PF02741.10 EDN06925.1 - 0.06 13.1 0.1 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 FTR, proximal lobe ECR1_N PF14382.1 EDN06927.1 - 2e-09 36.5 0.0 1.1e-08 34.2 0.0 2.4 2 1 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EDN06927.1 - 0.014 15.3 0.1 0.17 11.8 0.0 2.3 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Oxysterol_BP PF01237.13 EDN06928.1 - 8e-119 396.2 0.2 1.5e-118 395.3 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EDN06928.1 - 6.1e-39 131.9 0.1 1.4e-38 130.8 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EDN06928.1 - 0.0045 17.2 3.4 0.0079 16.4 0.1 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain MFS_1 PF07690.11 EDN06929.1 - 1.8e-38 132.1 41.4 2.1e-37 128.6 29.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN06929.1 - 2.5e-19 68.9 19.0 3.5e-19 68.4 13.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EDN06929.1 - 5e-17 61.6 8.9 5e-17 61.6 6.2 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter SH2_2 PF14633.1 EDN06930.1 - 1.2e-73 246.8 0.1 4.2e-73 245.0 0.0 2.0 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 EDN06930.1 - 3e-37 127.2 5.6 3e-37 127.2 3.9 3.6 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 EDN06930.1 - 1.6e-30 105.2 0.0 3.5e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EDN06930.1 - 2.3e-28 98.6 0.0 7.2e-28 97.0 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 EDN06930.1 - 1.6e-22 79.4 28.7 1.6e-22 79.4 19.9 5.5 5 1 1 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EDN06930.1 - 6.3e-21 74.5 5.4 2e-19 69.7 3.7 2.8 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_3 PF12836.2 EDN06930.1 - 0.018 15.0 0.0 0.056 13.3 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pkinase PF00069.20 EDN06931.1 - 3.8e-57 193.4 0.0 4.8e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06931.1 - 7.5e-32 110.4 0.0 1e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN06931.1 - 0.00027 19.9 0.0 0.0005 19.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EDN06931.1 - 0.022 13.5 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 EDN06931.1 - 0.16 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family IFRD PF05004.8 EDN06933.1 - 2e-34 119.1 0.0 3.1e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 EDN06933.1 - 0.0037 17.5 0.2 3 8.1 0.0 2.7 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 EDN06933.1 - 0.01 16.2 0.3 5.8 7.5 0.0 3.2 2 1 1 3 3 3 0 HEAT-like repeat PG_binding_2 PF08823.6 EDN06933.1 - 0.027 14.5 0.3 0.094 12.8 0.1 2.0 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Cnd3 PF12719.2 EDN06933.1 - 0.032 13.2 0.1 0.059 12.3 0.0 1.4 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Corona_nucleoca PF00937.13 EDN06933.1 - 0.56 9.0 6.9 0.91 8.4 4.8 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Arrestin_C PF02752.17 EDN06934.1 - 6.3e-25 87.8 0.0 1.7e-24 86.4 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EDN06934.1 - 2.9e-08 33.6 0.0 0.0001 22.1 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DDE_1 PF03184.14 EDN06935.1 - 6.4e-37 126.7 0.0 1.2e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN06935.1 - 1.8e-05 24.4 0.0 5.8e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN06935.1 - 0.0054 16.2 0.6 0.0054 16.2 0.4 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain TraG_N PF07916.6 EDN06935.1 - 0.73 8.1 3.6 1.1 7.6 2.5 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF2229 PF09989.4 EDN06935.1 - 4.1 6.7 8.7 37 3.6 6.0 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Borrelia_P83 PF05262.6 EDN06935.1 - 9.2 4.4 22.6 15 3.7 15.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Dicty_REP PF05086.7 EDN06936.1 - 3.7 5.1 22.6 0.3 8.7 5.1 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein DUF2370 PF10176.4 EDN06937.1 - 0.079 12.2 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) GATase_4 PF13230.1 EDN06939.1 - 8.6e-15 54.1 0.0 2.7e-13 49.2 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EDN06939.1 - 7e-10 38.9 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EDN06939.1 - 2.6e-06 26.3 0.0 0.00017 20.4 0.1 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Dynamin_N PF00350.18 EDN06940.1 - 4.2e-44 150.3 0.0 7.9e-44 149.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EDN06940.1 - 2.1e-09 36.5 0.1 1.6e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EDN06940.1 - 0.0011 18.9 0.0 0.0035 17.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDN06940.1 - 0.0034 17.8 0.0 0.0083 16.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EDN06940.1 - 0.0066 16.4 2.1 0.69 9.8 0.0 3.0 3 1 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.1 EDN06940.1 - 0.077 12.9 0.2 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Ribosomal_S6 PF01250.12 EDN06941.1 - 2.2e-06 27.4 0.0 3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Btz PF09405.5 EDN06943.1 - 3e-31 108.1 0.3 7e-31 106.9 0.2 1.6 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding RRM_1 PF00076.17 EDN06944.1 - 4.1e-26 90.4 0.4 1.3e-12 47.1 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN06944.1 - 7.4e-24 83.5 0.0 9.4e-11 41.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN06944.1 - 1.1e-08 34.7 0.2 0.0098 15.7 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDN06944.1 - 0.00077 19.1 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Pex14_N PF04695.8 EDN06944.1 - 0.24 11.4 5.1 0.36 10.8 0.8 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tom37_C PF11801.3 EDN06944.1 - 5.6 6.7 6.5 4.7 7.0 1.1 2.2 2 0 0 2 2 2 0 Tom37 C-terminal domain Ino80_Iec3 PF14612.1 EDN06945.1 - 7.1e-86 288.0 0.7 8.8e-86 287.7 0.5 1.1 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling IF2_N PF04760.10 EDN06945.1 - 0.093 12.4 0.2 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Pkinase PF00069.20 EDN06946.1 - 6.2e-17 61.6 0.0 8.8e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN06946.1 - 0.00013 21.1 0.0 0.00023 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase ZZ PF00569.12 EDN06947.1 - 8.4e-18 63.6 59.8 5e-07 29.1 4.0 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type LETM1 PF07766.8 EDN06948.1 - 7.6e-05 21.8 0.3 0.022 13.7 0.0 2.1 2 0 0 2 2 2 2 LETM1-like protein DUF1637 PF07847.7 EDN06949.1 - 0.041 13.2 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1637) BAF1_ABF1 PF04684.8 EDN06949.1 - 0.3 9.8 3.5 0.44 9.3 2.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Glyco_transf_20 PF00982.16 EDN06950.1 - 1.5e-148 495.2 0.0 2.1e-148 494.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EDN06950.1 - 4.5e-82 274.4 0.0 8.1e-82 273.6 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase HAD PF12710.2 EDN06950.1 - 0.09 12.9 0.4 0.67 10.0 0.3 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Acetyltransf_1 PF00583.19 EDN06951.1 - 6e-06 26.1 0.0 1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EDN06951.1 - 0.0021 18.1 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EDN06951.1 - 0.0024 17.9 0.0 0.0048 17.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EDN06951.1 - 0.033 14.0 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pyr_redox_3 PF13738.1 EDN06952.1 - 2.9e-19 69.9 0.0 1.3e-18 67.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDN06952.1 - 6.1e-09 35.2 0.0 7.7e-06 25.0 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EDN06952.1 - 1e-06 27.2 0.1 5.6e-06 24.8 0.1 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EDN06952.1 - 1.1e-05 25.3 0.0 3.3e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EDN06952.1 - 0.032 14.0 0.1 0.32 10.7 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.19 EDN06952.1 - 0.041 12.7 0.0 0.2 10.5 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase MFS_1 PF07690.11 EDN06953.1 - 2.2e-19 69.3 36.3 2.9e-19 68.9 25.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily SelB-wing_3 PF09107.6 EDN06953.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix PIRT PF15099.1 EDN06953.1 - 0.12 11.5 1.1 0.26 10.5 0.8 1.5 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family PP28 PF10252.4 EDN06954.1 - 3.2e-32 110.3 18.6 3.2e-32 110.3 12.9 3.2 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 Porphobil_deam PF01379.15 EDN06956.1 - 0.043 12.7 0.0 0.052 12.4 0.0 1.1 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain TT_ORF1 PF02956.9 EDN06957.1 - 9.4 4.5 8.2 10 4.4 5.7 1.0 1 0 0 1 1 1 0 TT viral orf 1 Sec7 PF01369.15 EDN06958.1 - 2.9e-42 144.5 0.0 9.5e-42 142.8 0.0 1.8 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 EDN06958.1 - 4.6e-17 62.2 0.0 8.6e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Lzipper-MIP1 PF14389.1 EDN06958.1 - 0.048 13.7 0.1 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Mto2_bdg PF12808.2 EDN06959.1 - 2.7e-36 123.4 27.5 2.1e-20 72.5 1.3 10.3 12 0 0 12 12 12 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Microtub_assoc PF07989.6 EDN06959.1 - 1.3e-23 82.5 8.7 1.3e-23 82.5 6.1 6.5 6 1 0 7 7 7 1 Microtubule associated Reo_sigmaC PF04582.7 EDN06959.1 - 1.3e-05 24.5 4.2 1.3e-05 24.5 2.9 5.6 5 2 2 7 7 7 2 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EDN06959.1 - 0.01 15.9 57.0 0.016 15.2 5.2 7.2 4 1 3 7 7 7 0 Fibrinogen alpha/beta chain family DUF904 PF06005.7 EDN06959.1 - 0.44 10.8 0.0 0.44 10.8 0.0 12.3 7 2 2 9 9 9 0 Protein of unknown function (DUF904) Zn_clus PF00172.13 EDN06961.1 - 1.9e-09 37.2 12.6 3.3e-09 36.5 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.15 EDN06962.1 - 1.3e-55 188.6 0.0 1.7e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Rad4 PF03835.10 EDN06964.1 - 0.018 14.4 1.2 0.026 13.9 0.8 1.3 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain DUF2057 PF09829.4 EDN06964.1 - 0.03 13.9 1.1 0.037 13.6 0.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Relaxase PF03432.9 EDN06964.1 - 0.13 11.6 0.2 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain DDE_1 PF03184.14 EDN06965.1 - 5.9e-37 126.9 0.0 9.4e-37 126.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN06965.1 - 3e-11 42.9 0.8 7.1e-10 38.5 0.0 3.0 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain PFL PF02901.10 EDN06965.1 - 0.016 13.6 1.0 0.024 13.0 0.7 1.3 1 0 0 1 1 1 0 Pyruvate formate lyase QRPTase_C PF01729.14 EDN06967.1 - 3.6e-47 160.0 0.2 3.4e-46 156.8 0.2 1.9 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EDN06967.1 - 2.8e-24 84.7 0.0 6e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain SWI-SNF_Ssr4 PF08549.5 EDN06967.1 - 0.035 12.4 0.6 0.043 12.1 0.4 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Ras PF00071.17 EDN06968.1 - 7.3e-26 90.4 0.0 3.2e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EDN06968.1 - 0.00094 19.6 0.0 0.0026 18.2 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein PAS_9 PF13426.1 EDN06969.1 - 2e-15 57.0 0.0 2.9e-05 24.4 0.0 3.7 3 0 0 3 3 3 3 PAS domain GATA PF00320.22 EDN06969.1 - 1.4e-14 53.0 7.9 4e-14 51.6 5.5 1.8 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EDN06969.1 - 5.7e-12 45.5 0.0 4.5e-09 36.2 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 EDN06969.1 - 3.9e-05 23.4 0.0 0.054 13.2 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 EDN06969.1 - 0.00012 22.0 0.0 0.19 11.6 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EDN06969.1 - 0.0011 19.0 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 2 PAS fold Cytochrome_C7 PF14522.1 EDN06969.1 - 0.14 11.7 1.4 0.33 10.5 0.9 1.6 1 0 0 1 1 1 0 Cytochrome c7 DMPK_coil PF08826.5 EDN06969.1 - 0.25 11.2 1.0 0.54 10.1 0.7 1.5 1 0 0 1 1 1 0 DMPK coiled coil domain like Peptidase_S41 PF03572.13 EDN06971.1 - 8.9e-10 38.2 0.0 2.1e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 Bromodomain PF00439.20 EDN06971.1 - 0.15 11.9 0.0 0.66 9.9 0.0 2.0 2 0 0 2 2 2 0 Bromodomain PLDc PF00614.17 EDN06972.1 - 2.1e-15 55.9 3.2 9.3e-07 28.4 0.1 3.1 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EDN06972.1 - 2.1e-12 46.8 0.0 8.6e-08 31.9 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain Abhydrolase_6 PF12697.2 EDN06973.1 - 1.7e-06 28.1 0.0 2.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN06973.1 - 3.6e-05 23.5 0.0 6.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDN06973.1 - 0.14 11.4 0.0 4.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ribosomal_L18e PF00828.14 EDN06974.1 - 2.7e-34 118.3 0.0 3.4e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 DEAD_2 PF06733.10 EDN06975.1 - 8.8e-19 67.5 3.5 1.7e-13 50.3 0.4 2.4 1 1 1 2 2 2 2 DEAD_2 Helicase_C_2 PF13307.1 EDN06975.1 - 1.5e-06 28.2 0.0 6.4e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain Sel1 PF08238.7 EDN06976.1 - 3.1e-15 56.2 24.5 5.8e-07 29.9 0.1 7.0 7 0 0 7 7 7 5 Sel1 repeat TPR_11 PF13414.1 EDN06976.1 - 0.0017 17.9 0.2 0.0017 17.9 0.1 2.7 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EDN06976.1 - 0.012 15.2 0.3 0.047 13.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDN06976.1 - 0.035 14.0 0.2 0.51 10.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDN06976.1 - 0.072 13.7 1.3 2.4 9.0 0.0 3.7 3 2 1 4 4 4 0 Tetratricopeptide repeat TBPIP PF07106.8 EDN06977.1 - 7.5e-15 54.8 0.2 9.9e-15 54.4 0.1 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4140 PF13600.1 EDN06977.1 - 0.0082 16.5 2.8 0.0084 16.5 0.9 1.8 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Macoilin PF09726.4 EDN06977.1 - 0.019 13.2 1.3 0.02 13.2 0.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Mito_fiss_reg PF05308.6 EDN06977.1 - 0.021 14.2 0.2 0.024 13.9 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF2267 PF10025.4 EDN06977.1 - 0.043 13.8 3.0 0.087 12.8 1.1 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) IncA PF04156.9 EDN06977.1 - 0.19 11.3 3.4 0.3 10.6 2.2 1.4 1 1 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 EDN06977.1 - 0.39 10.5 3.1 0.28 10.9 0.6 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.3 EDN06977.1 - 0.96 9.1 5.3 1.4 8.6 2.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 EDN06977.1 - 1.5 8.3 4.5 0.47 9.9 0.2 2.3 2 2 2 4 4 4 0 Septum formation initiator Mto2_bdg PF12808.2 EDN06977.1 - 2.1 8.4 5.9 18 5.5 0.8 3.1 2 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TPR_MLP1_2 PF07926.7 EDN06977.1 - 2.4 7.9 6.1 0.67 9.6 0.7 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SRP40_C PF05022.7 EDN06980.1 - 1.2e-21 76.9 0.7 4.1e-21 75.2 0.5 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain RNase_H PF00075.19 EDN06982.1 - 1.1e-14 54.9 0.0 1.9e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN06982.1 - 0.11 12.2 0.1 0.64 9.8 0.0 2.4 2 1 0 2 2 2 0 Reverse transcriptase-like Retrotrans_gag PF03732.12 EDN06983.1 - 3.3e-06 27.0 1.2 4.9e-06 26.5 0.8 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein EcoR124_C PF12008.3 EDN06983.1 - 0.015 14.5 0.8 0.017 14.3 0.5 1.0 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal DUF2408 PF10303.4 EDN06983.1 - 0.057 13.5 0.5 0.23 11.5 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Med15_fungi PF05397.7 EDN06983.1 - 0.062 13.2 0.2 0.077 12.9 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 15 RecO_N PF11967.3 EDN06983.1 - 0.13 12.1 0.1 0.27 11.1 0.1 1.6 1 1 0 1 1 1 0 Recombination protein O N terminal FlxA PF14282.1 EDN06985.1 - 0.012 15.5 3.0 0.16 11.9 2.2 2.2 2 0 0 2 2 2 0 FlxA-like protein GrpE PF01025.14 EDN06985.1 - 7.3 6.1 7.9 1.6e+02 1.7 5.5 2.1 1 1 0 1 1 1 0 GrpE rve PF00665.21 EDN06986.1 - 5.3e-17 62.0 0.2 3.5e-16 59.3 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain RVT_1 PF00078.22 EDN06986.1 - 2.5e-11 43.3 0.4 4.3e-10 39.3 0.0 2.6 2 1 1 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 EDN06986.1 - 0.0034 16.7 0.1 0.0085 15.4 0.0 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger DUF1729 PF08354.5 EDN06987.1 - 0.19 11.5 0.6 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) Bromodomain PF00439.20 EDN06989.1 - 4.6e-37 125.8 7.2 3.1e-18 65.4 0.2 2.8 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EDN06989.1 - 3.4e-16 59.0 0.7 7.7e-16 57.9 0.5 1.7 1 0 0 1 1 1 1 BAH domain DUF1353 PF07087.6 EDN06989.1 - 0.062 12.7 0.0 0.35 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) CDC45 PF02724.9 EDN06989.1 - 0.11 10.5 7.3 0.2 9.6 5.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EDN06989.1 - 0.12 11.8 7.1 0.31 10.5 4.9 1.7 1 0 0 1 1 1 0 Nucleoplasmin OTU PF02338.14 EDN06990.1 - 5.9e-13 49.4 0.0 1.2e-12 48.5 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2HC_2 PF13913.1 EDN06990.1 - 0.046 13.3 0.6 0.098 12.3 0.1 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Peptidase_C65 PF10275.4 EDN06990.1 - 0.047 13.0 0.0 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 Peptidase C65 Otubain 2-oxoacid_dh PF00198.18 EDN06991.1 - 7.3e-72 241.3 0.0 1.3e-71 240.5 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EDN06991.1 - 1.8e-18 65.9 0.8 3.2e-18 65.1 0.6 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 EDN06991.1 - 2.1e-05 23.8 1.0 0.0012 18.1 0.0 2.4 2 1 1 3 3 3 1 HlyD family secretion protein HlyD_3 PF13437.1 EDN06991.1 - 0.015 15.6 0.1 0.84 10.0 0.1 2.3 1 1 1 2 2 2 0 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EDN06991.1 - 0.022 14.4 0.1 0.16 11.6 0.1 2.1 1 1 1 2 2 2 0 Biotin-lipoyl like GCV_H PF01597.14 EDN06991.1 - 0.023 14.3 0.3 0.049 13.3 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD PF00529.15 EDN06991.1 - 0.034 13.4 0.1 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein Complex1_LYR PF05347.10 EDN06992.1 - 1.3e-07 31.2 0.9 1.3e-07 31.2 0.6 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDN06992.1 - 1.3e-05 25.3 2.7 1.4e-05 25.2 0.4 2.0 2 0 0 2 2 2 1 Complex1_LYR-like CtIP_N PF10482.4 EDN06992.1 - 0.42 10.4 6.5 8 6.2 0.0 2.1 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Histone PF00125.19 EDN06993.1 - 8.5e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDN06993.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDN06994.1 - 2.3e-22 78.9 0.2 3.2e-22 78.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDN06994.1 - 4.1e-05 23.5 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EDN06994.1 - 0.00021 21.4 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EDN06994.1 - 0.018 14.5 0.1 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 EDN06994.1 - 0.027 14.9 0.2 0.038 14.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Peptidase_C54 PF03416.14 EDN06995.1 - 1.3e-57 195.0 0.0 2.5e-45 154.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase family C54 Nop14 PF04147.7 EDN06995.1 - 2.5 5.9 12.8 0.18 9.6 5.1 1.7 2 0 0 2 2 2 0 Nop14-like family HTH_29 PF13551.1 EDN06996.1 - 1.3e-07 31.7 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.10 EDN06996.1 - 1.6e-07 31.0 0.0 4.2e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_33 PF13592.1 EDN06996.1 - 1.7e-06 27.4 0.0 4.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EDN06996.1 - 2.3e-06 27.0 0.5 0.00017 21.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 EDN06996.1 - 5.1e-05 22.7 0.0 0.00065 19.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.13 EDN06996.1 - 0.00012 21.8 0.0 0.00018 21.1 0.0 1.3 1 1 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.1 EDN06996.1 - 0.00027 20.8 0.0 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EDN06996.1 - 0.0033 18.2 0.0 0.017 15.9 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_IS630 PF01710.11 EDN06996.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Transposase GerE PF00196.14 EDN06996.1 - 0.056 12.7 0.9 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Terminase_5 PF06056.7 EDN06996.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Trp_repressor PF01371.14 EDN06996.1 - 0.13 12.1 0.1 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Trp repressor protein MYCBPAP PF14646.1 EDN06997.1 - 0.03 13.0 0.4 0.031 13.0 0.3 1.2 1 0 0 1 1 1 0 MYCBP-associated protein family Sigma70_ner PF04546.8 EDN06997.1 - 0.075 12.6 3.0 0.11 12.0 2.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.1 EDN06997.1 - 0.091 12.4 1.2 0.13 11.9 0.8 1.2 1 0 0 1 1 1 0 FAM176 family Nucleoplasmin PF03066.10 EDN06997.1 - 0.11 12.0 5.9 0.17 11.4 4.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF3381 PF11861.3 EDN06997.1 - 0.17 11.3 4.3 8.7 5.8 2.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) RXT2_N PF08595.6 EDN06997.1 - 0.19 11.4 2.6 0.3 10.8 1.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NESP55 PF06390.7 EDN06997.1 - 0.55 9.5 16.9 0.13 11.6 1.2 2.1 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Nucleo_P87 PF07267.6 EDN06997.1 - 1 7.9 3.5 1.4 7.5 2.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CobT PF06213.7 EDN06997.1 - 2.3 7.2 8.2 3.2 6.8 5.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Trypan_PARP PF05887.6 EDN06997.1 - 9.3 6.0 25.4 1.7 8.4 2.2 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) RVT_1 PF00078.22 EDN06999.1 - 1.7e-35 122.3 0.0 2.7e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN06999.1 - 1.1e-14 54.8 0.0 2.7e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN06999.1 - 1.3e-12 47.3 0.0 2.8e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase CEP44 PF15007.1 EDN07000.1 - 0.056 13.1 0.2 0.063 12.9 0.2 1.1 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 G-patch PF01585.18 EDN07001.1 - 6.8e-10 38.5 0.3 1.5e-09 37.5 0.2 1.6 1 0 0 1 1 1 1 G-patch domain R3H PF01424.17 EDN07001.1 - 4.2e-09 35.9 0.0 1e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 EDN07001.1 - 0.004 16.9 0.2 0.004 16.9 0.2 3.5 3 0 0 3 3 3 1 DExH-box splicing factor binding site DnaJ PF00226.26 EDN07002.1 - 1.2e-24 85.7 0.2 6.2e-24 83.5 0.2 2.3 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 EDN07002.1 - 2.3e-09 37.1 2.9 2.3e-09 37.1 2.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDN07002.1 - 3.1e-09 36.7 8.9 2.6e-08 33.7 0.9 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EDN07002.1 - 1.1e-06 28.6 3.3 0.0028 17.7 0.6 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EDN07002.1 - 0.00025 21.1 8.6 0.043 14.1 0.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type HsbA PF12296.3 EDN07002.1 - 0.005 16.6 0.8 0.015 15.1 0.6 1.8 1 0 0 1 1 1 1 Hydrophobic surface binding protein A AKAP95 PF04988.7 EDN07002.1 - 0.037 13.7 2.3 0.85 9.3 0.3 2.4 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_6 PF13912.1 EDN07002.1 - 0.056 13.3 7.3 0.49 10.3 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EDN07002.1 - 0.19 12.1 6.1 1.7 9.1 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger LIM PF00412.17 EDN07002.1 - 0.56 10.3 3.1 15 5.7 0.2 2.5 2 0 0 2 2 2 0 LIM domain zf-H2C2_2 PF13465.1 EDN07002.1 - 4.5 7.7 5.1 22 5.5 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain SPX PF03105.14 EDN07003.1 - 1e-41 143.5 0.0 1.4e-41 143.0 0.0 1.2 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EDN07003.1 - 3.6e-07 29.9 10.2 3.7e-07 29.9 5.7 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EDN07003.1 - 1.1e-05 25.1 9.6 2.3e-05 24.1 6.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDN07003.1 - 1.7e-05 24.3 10.2 1.7e-05 24.3 7.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN07003.1 - 5.2e-05 22.8 8.0 9.2e-05 22.0 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN07003.1 - 0.00019 21.0 9.5 0.00041 20.0 6.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDN07003.1 - 0.00049 20.0 11.1 0.0012 18.8 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CotJA PF11007.3 EDN07003.1 - 0.0062 16.1 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 Spore coat associated protein JA (CotJA) zf-RING_UBOX PF13445.1 EDN07003.1 - 0.016 14.9 7.9 0.016 14.9 5.5 2.2 2 0 0 2 2 2 0 RING-type zinc-finger DUF3347 PF11827.3 EDN07003.1 - 0.029 14.3 0.2 0.052 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) zf-MIZ PF02891.15 EDN07003.1 - 0.059 12.9 6.5 0.12 11.8 4.5 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-P11 PF03854.9 EDN07003.1 - 1.5 8.3 9.3 46 3.5 6.7 2.4 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.1 EDN07003.1 - 4 7.0 8.1 14 5.3 5.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain F-box-like PF12937.2 EDN07004.1 - 9e-08 31.7 1.0 1.8e-07 30.7 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN07004.1 - 1.2e-07 31.1 0.3 2.1e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 EDN07004.1 - 0.073 13.4 0.0 0.16 12.3 0.0 1.6 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A YccV-like PF08755.6 EDN07005.1 - 7.5e-19 67.5 0.2 1.3e-18 66.7 0.2 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like DUF1918 PF08940.6 EDN07007.1 - 0.0041 16.4 0.7 2.4 7.5 0.0 4.0 4 0 0 4 4 4 2 Domain of unknown function (DUF1918) Nrap PF03813.9 EDN07008.1 - 2.6e-303 1008.3 0.0 1.7e-237 790.4 0.0 2.0 1 1 1 2 2 2 2 Nrap protein PINIT PF14324.1 EDN07008.1 - 0.1 12.6 0.5 11 6.0 0.0 2.4 2 0 0 2 2 2 0 PINIT domain Cys_Met_Meta_PP PF01053.15 EDN07009.1 - 4.5e-34 117.3 0.0 6e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EDN07009.1 - 0.019 13.9 0.0 0.057 12.3 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II DUF1330 PF07045.6 EDN07009.1 - 0.1 12.4 0.0 4.2 7.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1330) MRP-L20 PF12824.2 EDN07011.1 - 1.2e-60 204.1 6.1 1.5e-60 203.9 4.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF1421 PF07223.6 EDN07011.1 - 0.058 13.1 8.8 0.065 13.0 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) CENP-B_N PF04218.8 EDN07011.1 - 0.07 12.5 0.0 0.2 11.1 0.0 1.8 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Peptidase_M20 PF01546.23 EDN07012.1 - 3.3e-25 88.6 0.0 5e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EDN07012.1 - 5.7e-14 51.8 0.0 9.9e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain SMC_N PF02463.14 EDN07013.1 - 1.3e-21 76.8 10.7 5.9e-21 74.7 7.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EDN07013.1 - 1.3e-09 38.6 30.9 1.3e-09 38.6 21.4 5.0 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EDN07013.1 - 4.3e-09 36.7 9.3 1.1e-06 28.8 0.5 2.9 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EDN07013.1 - 0.00051 19.5 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EDN07013.1 - 0.07 13.4 0.1 0.07 13.4 0.0 5.1 4 2 0 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 EDN07013.1 - 0.088 11.9 15.7 0.026 13.7 1.8 3.4 3 1 0 3 3 3 0 Reovirus sigma C capsid protein AAA_15 PF13175.1 EDN07013.1 - 6.5 5.6 24.9 0.24 10.4 10.8 2.8 2 1 0 2 2 2 0 AAA ATPase domain WD40 PF00400.27 EDN07018.1 - 4.1e-08 32.7 3.3 0.0014 18.4 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat DIOX_N PF14226.1 EDN07019.1 - 7.9e-30 103.7 0.3 2e-27 96.0 0.1 3.0 2 1 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EDN07019.1 - 9.5e-09 35.4 0.0 2.4e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EDN07020.1 - 8.9e-41 139.7 42.6 9.4e-40 136.3 29.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.14 EDN07020.1 - 1e-06 27.6 2.9 0.00011 20.8 0.1 2.4 2 0 0 2 2 2 2 LacY proton/sugar symporter DNA_primase_S PF01896.14 EDN07021.1 - 5.4e-54 181.9 0.0 8.7e-54 181.2 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit MAM33 PF02330.11 EDN07022.1 - 2.6e-32 112.2 4.5 9.4e-31 107.1 3.1 2.0 1 1 0 1 1 1 1 Mitochondrial glycoprotein DUF2962 PF11176.3 EDN07023.1 - 7.5e-52 175.0 1.0 8.5e-52 174.8 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) XPG_I PF00867.13 EDN07024.1 - 2.2e-25 88.4 0.1 4.6e-25 87.5 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EDN07024.1 - 2.5e-23 82.2 0.0 7e-23 80.8 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.2 EDN07024.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing TPR_2 PF07719.12 EDN07024.1 - 0.03 14.2 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Fig1 PF12351.3 EDN07025.1 - 3.1e-56 190.1 6.4 3.1e-56 190.1 4.4 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EDN07025.1 - 7.7e-07 28.8 8.2 1.6e-06 27.8 5.7 1.6 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EDN07025.1 - 0.0031 16.4 10.4 0.0031 16.4 7.2 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF2410 PF10307.4 EDN07026.1 - 1.4e-85 285.6 0.0 2.1e-85 285.1 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) zf-RING_2 PF13639.1 EDN07027.1 - 5.4e-08 32.5 5.6 9.5e-08 31.7 3.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDN07027.1 - 8e-07 28.9 4.8 1.4e-06 28.2 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN07027.1 - 1.5e-06 27.7 4.7 2.5e-06 27.0 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN07027.1 - 1.5e-06 27.7 3.3 2.4e-06 27.1 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDN07027.1 - 0.0003 20.8 5.1 0.00088 19.3 3.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger Peptidase_C41 PF05417.6 EDN07027.1 - 0.13 11.8 0.2 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Hepatitis E cysteine protease zf-RING_5 PF14634.1 EDN07027.1 - 0.47 10.2 3.1 0.84 9.4 2.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Drc1-Sld2 PF11719.3 EDN07028.1 - 8.8e-137 456.6 10.5 1e-136 456.4 7.3 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein DEAD PF00270.24 EDN07032.1 - 7.3e-11 41.8 0.0 2.4e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN07032.1 - 0.00035 20.4 0.1 0.0031 17.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit rve PF00665.21 EDN07033.1 - 2.2e-06 27.7 0.0 4.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EDN07034.1 - 2.3e-35 121.9 0.0 4.7e-35 120.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN07034.1 - 1.9e-14 54.1 0.0 4.3e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN07034.1 - 3.3e-13 49.2 0.0 6.8e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Acetyltransf_1 PF00583.19 EDN07035.1 - 1.7e-10 40.7 0.1 2.8e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EDN07035.1 - 0.0012 18.9 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDN07035.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EDN07035.1 - 0.0031 17.6 0.0 0.0061 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EDN07035.1 - 0.037 13.9 0.0 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain T2SF PF00482.18 EDN07036.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F FUSC PF04632.7 EDN07036.1 - 0.17 10.2 2.6 0.26 9.6 1.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-Q PF13094.1 EDN07036.1 - 3.4 7.6 14.9 3.4 7.6 6.3 2.7 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EDN07036.1 - 8.2 5.9 6.2 0.5 9.9 0.4 1.7 2 0 0 2 2 2 0 IncA protein HET PF06985.6 EDN07037.1 - 0.00092 19.3 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PCI PF01399.22 EDN07038.1 - 1.9e-10 41.0 0.8 5.8e-09 36.2 0.0 3.1 2 0 0 2 2 2 1 PCI domain G-gamma PF00631.17 EDN07039.1 - 5.3e-25 86.9 0.1 5.8e-25 86.8 0.0 1.0 1 0 0 1 1 1 1 GGL domain Rdx PF10262.4 EDN07040.1 - 7.6e-30 102.7 0.0 1.1e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Rdx family PDEase_I PF00233.14 EDN07041.1 - 1.1e-41 143.1 0.0 1.7e-41 142.5 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DEAD PF00270.24 EDN07042.1 - 5.2e-12 45.5 0.0 1.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN07042.1 - 1.3e-08 34.5 0.0 2.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 EDN07042.1 - 4.7e-06 26.6 0.4 4.9e-05 23.4 0.1 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain ResIII PF04851.10 EDN07042.1 - 0.006 16.4 0.0 0.041 13.7 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HTH_6 PF01418.12 EDN07042.1 - 0.044 13.5 0.3 0.75 9.5 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain, rpiR family DUF4332 PF14229.1 EDN07042.1 - 0.052 13.5 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) HTH_45 PF14947.1 EDN07042.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix BAH PF01426.13 EDN07044.1 - 2.1e-16 59.7 0.0 3.6e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.1 EDN07045.1 - 6.7e-23 80.6 9.8 2.9e-22 78.6 0.4 3.5 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EDN07045.1 - 2.5e-22 78.9 0.2 2.5e-22 78.9 0.1 3.1 4 0 0 4 4 4 1 PHD-zinc-finger like domain PHD_2 PF13831.1 EDN07045.1 - 6e-08 31.8 4.7 6e-08 31.8 3.2 4.1 5 0 0 5 5 5 1 PHD-finger PHD PF00628.24 EDN07045.1 - 6.5e-06 25.7 8.3 6.5e-06 25.7 5.7 4.7 5 0 0 5 5 5 2 PHD-finger C1_1 PF00130.17 EDN07045.1 - 0.0077 15.9 2.7 0.0077 15.9 1.8 4.4 4 1 1 5 5 5 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EDN07045.1 - 0.021 14.5 16.3 0.033 13.9 1.6 3.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EDN07045.1 - 0.17 11.9 23.7 0.87 9.6 5.6 3.1 2 0 0 2 2 2 0 RING-like domain SKG6 PF08693.5 EDN07045.1 - 3.6 6.9 4.0 7.5 5.9 0.6 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF1524 PF07510.6 EDN07046.1 - 0.089 12.6 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1524) Rieske PF00355.21 EDN07048.1 - 0.00026 20.5 0.4 0.00049 19.6 0.3 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain tRNA-synt_1f PF01921.13 EDN07048.1 - 0.13 10.8 0.0 0.68 8.5 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (K) DDE_1 PF03184.14 EDN07049.1 - 1.9e-25 89.2 0.0 8.8e-25 87.1 0.0 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN07049.1 - 1.2e-14 53.8 0.5 3.1e-14 52.5 0.1 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN07049.1 - 0.00083 18.8 0.0 0.0022 17.5 0.0 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN07049.1 - 0.0036 17.0 0.0 0.0071 16.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease AAA_27 PF13514.1 EDN07049.1 - 0.043 11.5 0.9 0.062 10.9 0.6 1.1 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 EDN07050.1 - 1.4e-09 37.4 0.0 2.4e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN07050.1 - 2.4e-07 30.7 0.0 1.4e-06 28.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EDN07050.1 - 0.0001 21.4 0.3 0.00025 20.1 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EDN07050.1 - 0.0025 16.9 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EDN07050.1 - 0.04 13.4 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L38e PF01781.13 EDN07050.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal L38e protein family EcKinase PF02958.15 EDN07050.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Seadorna_VP7 PF07387.6 EDN07050.1 - 0.21 10.3 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CLTH PF10607.4 EDN07053.1 - 1.7e-32 112.1 0.0 2.4e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DDE_Tnp_1_7 PF13843.1 EDN07054.1 - 1.2e-63 215.3 0.0 2.3e-42 145.3 0.0 2.0 2 0 0 2 2 2 2 Transposase IS4 APH PF01636.18 EDN07055.1 - 8.2e-13 48.6 0.0 1.6e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EDN07055.1 - 0.00048 18.8 0.0 0.00096 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.15 EDN07055.1 - 0.013 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 EDN07055.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PG_binding_1 PF01471.13 EDN07057.1 - 0.0067 16.3 0.0 1 9.3 0.0 3.0 3 0 0 3 3 3 1 Putative peptidoglycan binding domain TMCO5 PF14992.1 EDN07057.1 - 0.22 10.6 1.1 0.37 9.8 0.8 1.3 1 0 0 1 1 1 0 TMCO5 family zf-Tim10_DDP PF02953.10 EDN07058.1 - 2.4e-24 84.3 2.4 3.1e-24 84.0 1.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger tRNA-synt_2 PF00152.15 EDN07059.1 - 3.9e-49 167.2 0.0 7.2e-39 133.4 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDN07059.1 - 2.9e-07 30.2 0.0 5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain BTB PF00651.26 EDN07060.1 - 2.2e-06 27.5 0.0 9.3e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 EDN07060.1 - 0.037 14.1 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DUF433 PF04255.9 EDN07061.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF433) TPR_2 PF07719.12 EDN07061.1 - 0.045 13.6 0.2 0.12 12.3 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDN07061.1 - 0.1 12.2 0.8 0.25 10.9 0.6 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_L18ae PF01775.12 EDN07062.1 - 6.6e-60 200.4 0.9 8.5e-60 200.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain NAD_binding_1 PF00175.16 EDN07064.1 - 6e-30 104.0 0.0 1.3e-29 102.9 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EDN07064.1 - 7.9e-19 67.6 0.0 1.9e-18 66.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EDN07064.1 - 1.3e-09 38.1 0.0 1.6e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Phosphonate-bd PF12974.2 EDN07064.1 - 0.089 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein AAR2 PF05282.6 EDN07064.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 AAR2 protein HMG_box PF00505.14 EDN07065.1 - 2.1e-11 43.9 3.7 2.1e-11 43.9 2.6 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDN07065.1 - 2.6e-06 27.7 2.7 2.6e-06 27.7 1.9 2.2 2 0 0 2 2 2 1 HMG-box domain NOA36 PF06524.7 EDN07065.1 - 0.016 14.4 0.9 1.4 8.1 2.3 2.2 2 0 0 2 2 2 0 NOA36 protein Nucleoplasmin PF03066.10 EDN07065.1 - 0.73 9.3 12.4 1.5 8.3 8.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin EBV-NA3 PF05009.7 EDN07065.1 - 2.6 7.2 6.1 4.3 6.5 4.2 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CDC45 PF02724.9 EDN07065.1 - 5.7 4.8 13.5 9.6 4.0 9.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Amidohydro_1 PF01979.15 EDN07066.1 - 3.2e-59 201.2 0.8 5.7e-59 200.4 0.6 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EDN07066.1 - 3.1e-53 179.0 1.6 7.3e-53 177.8 1.1 1.7 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EDN07066.1 - 7.8e-42 141.1 0.1 1.3e-40 137.2 0.0 2.3 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 EDN07066.1 - 5.5e-38 128.9 0.1 1.4e-37 127.6 0.1 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EDN07066.1 - 1.9e-06 27.5 3.2 1.9e-06 27.5 2.2 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EDN07066.1 - 1.9e-05 24.0 0.2 0.0089 15.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Lactamase_B PF00753.22 EDN07067.1 - 0.0044 16.7 0.0 0.013 15.2 0.0 1.7 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EDN07067.1 - 0.0066 16.0 0.7 0.064 12.7 0.5 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Choline_sulf_C PF12411.3 EDN07067.1 - 0.057 13.2 0.3 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal NPR2 PF06218.6 EDN07070.1 - 1.8e-131 438.8 0.0 3.3e-131 437.9 0.0 1.4 2 0 0 2 2 2 1 Nitrogen permease regulator 2 Afi1 PF07792.7 EDN07070.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ada3 PF10198.4 EDN07071.1 - 6.4e-43 145.6 0.0 6.4e-43 145.6 0.0 1.8 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 zf-RING_2 PF13639.1 EDN07072.1 - 1.6e-13 50.2 5.8 3.1e-13 49.3 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EDN07072.1 - 1.5e-06 27.8 3.4 2.8e-06 26.9 2.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDN07072.1 - 1.5e-06 28.0 4.9 3e-06 27.1 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN07072.1 - 2.7e-06 26.9 1.9 4.8e-06 26.1 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN07072.1 - 8.6e-06 25.3 4.1 1.5e-05 24.5 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDN07072.1 - 5e-05 23.3 3.7 0.00012 22.1 2.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EDN07072.1 - 0.0017 18.1 2.3 0.0038 17.0 1.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EDN07072.1 - 0.0023 17.6 1.3 0.0084 15.8 0.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EDN07072.1 - 0.057 13.0 4.0 0.1 12.2 2.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EDN07072.1 - 0.11 12.0 3.4 0.24 10.9 2.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1049 PF06305.6 EDN07072.1 - 0.19 11.2 1.7 0.39 10.2 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) zf-RING-like PF08746.6 EDN07072.1 - 0.21 11.5 1.5 0.48 10.4 1.1 1.5 1 0 0 1 1 1 0 RING-like domain HAMP PF00672.20 EDN07072.1 - 0.21 11.7 2.4 0.65 10.2 1.7 1.8 1 0 0 1 1 1 0 HAMP domain zf-MIZ PF02891.15 EDN07072.1 - 0.42 10.1 4.7 1.2 8.6 3.3 1.9 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.1 EDN07072.1 - 0.44 10.4 6.1 1.4 8.8 4.2 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 EDN07072.1 - 5.6 6.5 8.3 0.35 10.3 1.8 1.9 2 0 0 2 2 2 0 P-11 zinc finger FRG1 PF06229.7 EDN07073.1 - 3.3e-62 209.3 0.1 4.5e-62 208.9 0.1 1.2 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EDN07073.1 - 0.024 14.7 0.0 0.083 12.9 0.0 2.0 1 0 0 1 1 1 0 Fascin domain TmoB PF06234.7 EDN07073.1 - 0.15 11.9 0.1 0.28 11.0 0.1 1.4 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) ADH_N PF08240.7 EDN07074.1 - 1.5e-26 92.2 1.5 6.5e-26 90.2 0.9 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN07074.1 - 1.6e-15 56.7 0.0 2.6e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN07074.1 - 0.00056 20.7 0.0 0.0011 19.8 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EDN07074.1 - 0.0039 17.7 0.0 0.0086 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_7 PF13241.1 EDN07074.1 - 0.017 15.3 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Gp_dh_N PF00044.19 EDN07074.1 - 0.024 14.6 0.0 0.056 13.3 0.0 1.6 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EDN07074.1 - 0.028 13.4 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADH_4Fe-4S PF10589.4 EDN07074.1 - 0.032 13.3 2.4 0.11 11.6 1.6 1.9 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region FAD_binding_3 PF01494.14 EDN07074.1 - 0.041 12.9 0.3 0.063 12.3 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain HECT PF00632.20 EDN07075.1 - 1.3e-76 257.8 0.0 1.7e-76 257.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4360 PF14273.1 EDN07079.1 - 4.8e-60 202.3 0.1 5.6e-60 202.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Ribosomal_L15e PF00827.12 EDN07080.1 - 4.6e-91 303.5 11.5 5.3e-91 303.3 7.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 Nucleoplasmin PF03066.10 EDN07081.1 - 1.4 8.4 7.9 3.2 7.2 5.5 1.6 1 0 0 1 1 1 0 Nucleoplasmin Spt5_N PF11942.3 EDN07081.1 - 4.9 7.8 24.1 4.6 7.9 12.5 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal NOA36 PF06524.7 EDN07081.1 - 8.8 5.4 11.2 16 4.6 7.8 1.4 1 0 0 1 1 1 0 NOA36 protein DUF2076 PF09849.4 EDN07081.1 - 9.8 6.1 11.9 22 5.0 8.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PSP1 PF04468.7 EDN07082.1 - 2.5e-31 107.4 1.6 4.1e-31 106.8 1.1 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.6 EDN07085.1 - 1.4e-26 91.9 0.0 3.6e-26 90.5 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EDN07085.1 - 3.9e-22 77.7 0.0 6.2e-22 77.1 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain RasGEF PF00617.14 EDN07086.1 - 2.3e-45 154.6 0.2 4.1e-45 153.8 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EDN07086.1 - 7.7e-16 58.0 0.0 1.7e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 EDN07086.1 - 7.5e-11 42.5 0.0 1.7e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EDN07086.1 - 0.1 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EDN07086.1 - 0.11 12.0 0.0 0.3 10.5 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Complex1_LYR_2 PF13233.1 EDN07087.1 - 2.1e-20 73.1 1.0 2.6e-20 72.8 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EDN07087.1 - 0.055 13.2 0.8 0.14 12.0 0.5 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDN07087.1 - 1.8 8.8 4.6 7 6.9 3.2 2.0 1 1 0 1 1 1 0 Complex1_LYR-like Cyclin_N PF00134.18 EDN07088.1 - 8.6e-12 44.7 0.0 1.7e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EDN07088.1 - 1.4e-08 35.2 0.0 2.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin CaM_bdg_C0 PF10562.4 EDN07089.1 - 0.087 12.6 0.0 0.087 12.6 0.0 1.8 2 0 0 2 2 2 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit Ras PF00071.17 EDN07090.1 - 6e-09 35.4 0.0 3.5e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EDN07090.1 - 0.00063 20.2 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein ThiI PF02568.9 EDN07090.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) ODC_AZ PF02100.12 EDN07092.1 - 1.4e-22 79.1 0.0 2.3e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Yippee-Mis18 PF03226.9 EDN07093.1 - 2.2e-25 88.5 0.1 3.6e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EDN07093.1 - 0.0094 15.8 1.6 0.067 13.0 0.0 2.1 2 0 0 2 2 2 1 C-terminal domain of RIG-I FAM72 PF14976.1 EDN07093.1 - 0.039 13.7 0.1 0.084 12.7 0.1 1.6 1 0 0 1 1 1 0 FAM72 protein SHNi-TPR PF10516.4 EDN07094.1 - 2.8e-15 55.2 1.1 2.8e-15 55.2 0.8 3.0 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.1 EDN07094.1 - 2.6e-07 30.4 8.2 0.00082 19.2 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDN07094.1 - 1.6e-06 27.6 5.8 0.011 15.3 0.0 2.9 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 EDN07094.1 - 0.0085 16.7 4.0 0.66 10.7 0.8 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDN07094.1 - 0.024 14.2 3.1 1.2 8.9 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PCAF_N PF06466.6 EDN07094.1 - 0.025 13.9 0.3 0.038 13.3 0.2 1.2 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain TPR_7 PF13176.1 EDN07094.1 - 0.032 14.0 2.1 4.7 7.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat UBN_AB PF14075.1 EDN07094.1 - 0.23 11.0 5.6 0.18 11.4 1.6 2.2 2 0 0 2 2 2 0 Ubinuclein conserved middle domain TPR_2 PF07719.12 EDN07094.1 - 0.57 10.2 14.9 0.62 10.1 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat KBP_C PF12309.3 EDN07094.1 - 0.6 9.0 7.6 1.7 7.5 5.3 1.7 1 1 0 1 1 1 0 KIF-1 binding protein C terminal TPR_14 PF13428.1 EDN07094.1 - 0.64 10.8 3.6 25 5.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 EDN07094.1 - 1.9 8.3 6.0 2.7 7.8 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1664 PF07889.7 EDN07094.1 - 2.4 7.9 7.7 0.8 9.5 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-B_dimeris PF09026.5 EDN07094.1 - 3 8.1 8.4 10 6.4 5.8 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_E_B PF04042.11 EDN07095.1 - 3.5e-48 163.6 0.1 4.8e-48 163.1 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Med14 PF08638.6 EDN07096.1 - 8.6e-75 250.2 0.0 1.7e-74 249.3 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 RVT_2 PF07727.9 EDN07098.1 - 5.5e-58 195.8 0.0 8.2e-58 195.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN07098.1 - 2.3e-15 56.7 0.0 5.3e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 EDN07098.1 - 0.00021 21.0 4.1 0.00044 20.0 2.8 1.6 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.1 EDN07098.1 - 0.0021 17.6 0.4 0.0052 16.3 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain UBN2 PF14223.1 EDN07098.1 - 0.0054 16.5 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Thioredoxin PF00085.15 EDN07099.1 - 9.8e-64 211.5 8.2 5.6e-32 109.5 0.1 4.3 4 1 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EDN07099.1 - 2.1e-50 171.1 1.4 3.7e-36 124.6 0.2 3.4 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EDN07099.1 - 3.7e-10 39.7 0.0 0.0011 18.9 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EDN07099.1 - 7.6e-10 38.9 1.2 0.00047 20.3 0.1 3.5 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDN07099.1 - 1.3e-09 38.0 0.3 0.0029 17.6 0.0 4.3 4 1 1 5 5 5 2 Thioredoxin-like Calsequestrin PF01216.12 EDN07099.1 - 1.4e-08 33.9 1.7 3.2e-08 32.7 0.1 2.2 3 0 0 3 3 3 1 Calsequestrin AhpC-TSA PF00578.16 EDN07099.1 - 2.2e-07 30.5 0.1 0.0029 17.2 0.0 2.7 2 0 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.8 EDN07099.1 - 1e-05 25.4 0.1 0.59 10.0 0.0 3.4 3 0 0 3 3 3 2 ERp29, N-terminal domain Redoxin PF08534.5 EDN07099.1 - 1.2e-05 24.9 1.4 0.039 13.5 0.0 3.4 3 0 0 3 3 3 2 Redoxin Thioredoxin_4 PF13462.1 EDN07099.1 - 0.0075 16.2 1.4 2.9 7.8 0.0 3.5 3 1 1 4 4 4 1 Thioredoxin RVT_1 PF00078.22 EDN07100.1 - 8.3e-35 120.0 0.0 1.7e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN07100.1 - 1.9e-15 56.5 0.0 9.8e-15 54.2 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN07100.1 - 0.00052 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EDN07100.1 - 0.00054 19.7 4.1 0.00054 19.7 2.9 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 EDN07100.1 - 0.92 9.2 12.8 3.1 7.5 1.0 2.7 1 1 1 2 2 2 0 Zinc knuckle gag_pre-integrs PF13976.1 EDN07101.1 - 1.2e-05 24.8 0.3 1.9e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain Baculo_E25 PF05274.6 EDN07102.1 - 0.089 12.3 0.9 0.087 12.4 0.7 1.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein E25 RVT_1 PF00078.22 EDN07103.1 - 3e-36 124.7 0.0 4.3e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UDG PF03167.14 EDN07104.1 - 9e-24 83.6 0.1 1.3e-23 83.1 0.1 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Actin PF00022.14 EDN07105.1 - 3e-111 371.6 0.0 3.7e-111 371.3 0.0 1.0 1 0 0 1 1 1 1 Actin Hep_59 PF07052.6 EDN07106.1 - 1.5e-21 76.6 0.2 1.5e-21 76.6 0.1 3.1 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 TRP PF06011.7 EDN07107.1 - 1.3e-142 475.4 15.8 1.7e-142 475.0 11.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EDN07107.1 - 6e-36 123.5 0.3 9.6e-36 122.9 0.2 1.3 1 0 0 1 1 1 1 ML-like domain RCR PF12273.3 EDN07107.1 - 0.064 13.8 0.0 0.064 13.8 0.0 2.1 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red E1_DerP2_DerF2 PF02221.10 EDN07107.1 - 0.085 13.1 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 ML domain IncA PF04156.9 EDN07107.1 - 1.6 8.3 18.8 0.4 10.2 1.7 3.5 3 0 0 3 3 3 0 IncA protein SCIMP PF15050.1 EDN07107.1 - 3.1 7.6 6.7 1.3 8.9 0.2 2.8 2 0 0 2 2 2 0 SCIMP protein DUF3487 PF11990.3 EDN07107.1 - 3.5 7.0 9.8 1.5 8.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) TRP PF06011.7 EDN07108.1 - 5.7e-36 124.0 1.4 7.3e-36 123.6 1.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EDN07108.1 - 1.7e-25 89.6 0.0 2.6e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 ML-like domain IncA PF04156.9 EDN07108.1 - 0.047 13.2 1.4 0.076 12.5 0.9 1.3 1 0 0 1 1 1 0 IncA protein RRM_1 PF00076.17 EDN07109.1 - 2.3e-28 97.6 0.1 4.8e-18 64.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN07109.1 - 2.1e-20 72.4 0.0 9.2e-14 51.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN07109.1 - 3.6e-09 36.3 0.1 2.8e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDN07109.1 - 0.0013 18.5 0.1 0.37 10.6 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EDN07109.1 - 0.059 13.1 0.0 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RabGAP-TBC PF00566.13 EDN07110.1 - 4.1e-38 130.9 0.0 1.6e-37 129.0 0.0 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RrnaAD PF00398.15 EDN07111.1 - 1.2e-24 86.7 0.0 1.5e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EDN07111.1 - 8.4e-11 41.9 0.0 3.1e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN07111.1 - 2.8e-08 34.3 0.0 4.6e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN07111.1 - 3.8e-06 26.3 0.1 5.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EDN07111.1 - 8e-06 26.2 0.0 1.5e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDN07111.1 - 1.4e-05 24.2 0.0 2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EDN07111.1 - 2.1e-05 24.1 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 EDN07111.1 - 2.2e-05 24.8 0.0 6.4e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN07111.1 - 2.8e-05 23.9 0.0 3.3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN07111.1 - 0.00025 20.6 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EDN07111.1 - 0.00054 19.2 0.0 0.00062 19.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 EDN07111.1 - 0.0021 17.1 0.0 0.0036 16.3 0.0 1.3 1 1 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EDN07111.1 - 0.0047 16.0 0.0 0.0054 15.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.11 EDN07111.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.3 1 1 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.8 EDN07111.1 - 0.017 14.2 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 EDN07111.1 - 0.019 13.8 0.0 0.021 13.7 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_25 PF13649.1 EDN07111.1 - 0.021 15.1 0.0 0.033 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EDN07111.1 - 0.029 14.3 0.0 0.038 13.9 0.0 1.1 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_28 PF02636.12 EDN07111.1 - 0.04 13.3 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DOT1 PF08123.8 EDN07111.1 - 0.052 12.8 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 NodS PF05401.6 EDN07111.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EDN07111.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EDN07111.1 - 0.14 10.8 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PRP1_N PF06424.7 EDN07112.1 - 8.4e-55 184.7 5.6 2.6e-54 183.1 3.9 1.9 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EDN07112.1 - 9.5e-27 91.0 29.5 0.00022 21.5 0.2 13.1 5 3 9 14 14 13 7 Tetratricopeptide repeat TPR_19 PF14559.1 EDN07112.1 - 1.7e-20 73.1 17.0 2.5e-05 24.5 0.1 9.2 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EDN07112.1 - 9.7e-19 67.5 21.5 8.5e-05 23.1 0.1 8.6 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 EDN07112.1 - 1.4e-12 47.1 12.7 2.4e-05 23.8 0.2 7.6 6 2 3 9 9 9 4 TPR repeat TPR_2 PF07719.12 EDN07112.1 - 1.4e-11 43.3 10.6 0.017 15.0 0.0 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EDN07112.1 - 5.5e-08 32.0 1.1 0.024 14.2 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDN07112.1 - 6.2e-07 28.7 0.2 0.32 10.8 0.1 6.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDN07112.1 - 6.7e-06 25.9 2.8 0.12 12.3 0.3 5.2 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDN07112.1 - 0.00026 20.9 9.4 8.8 6.8 0.2 7.8 8 1 1 9 9 9 1 Tetratricopeptide repeat Apc3 PF12895.2 EDN07112.1 - 0.00033 20.7 0.3 1.2 9.3 0.0 3.8 4 0 0 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Suf PF05843.9 EDN07112.1 - 0.0022 17.7 1.4 0.94 9.1 0.0 3.9 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_7 PF13176.1 EDN07112.1 - 0.041 13.6 5.7 4.9 7.1 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Cutinase PF01083.17 EDN07112.1 - 0.14 11.9 0.0 19 4.9 0.0 2.6 1 1 1 2 2 2 0 Cutinase TPR_6 PF13174.1 EDN07112.1 - 0.47 11.0 18.7 20 5.9 0.1 8.3 10 0 0 10 10 8 0 Tetratricopeptide repeat SAGA-Tad1 PF12767.2 EDN07113.1 - 6.3e-37 127.5 0.0 3e-30 105.7 0.0 2.2 1 1 1 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit Adhesin_Dr PF04619.7 EDN07113.1 - 0.082 12.6 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Dr-family adhesin FUSC_2 PF13515.1 EDN07114.1 - 3.1e-30 104.7 7.9 3.1e-30 104.7 5.5 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 EDN07114.1 - 1.9e-08 33.4 10.9 0.00029 19.6 5.1 3.5 3 1 0 3 3 3 2 Aluminium activated malate transporter FUSC PF04632.7 EDN07114.1 - 8.9e-07 27.7 2.1 8.9e-07 27.7 1.5 2.9 2 1 2 4 4 4 2 Fusaric acid resistance protein family DUF2421 PF10334.4 EDN07114.1 - 0.0034 17.0 1.0 0.013 15.1 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF4026 PF13218.1 EDN07114.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) DUF2422 PF10337.4 EDN07114.1 - 0.61 8.8 7.1 0.97 8.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) WD40 PF00400.27 EDN07115.1 - 2.4e-54 179.3 23.3 4.5e-10 39.0 0.3 11.5 11 0 0 11 11 11 9 WD domain, G-beta repeat IKI3 PF04762.7 EDN07115.1 - 0.061 11.1 0.2 7.7 4.1 0.1 2.9 2 1 1 3 3 3 0 IKI3 family PQQ_3 PF13570.1 EDN07115.1 - 0.72 10.2 9.5 6.3 7.2 0.2 5.3 5 0 0 5 5 5 0 PQQ-like domain Proteasome_A_N PF10584.4 EDN07115.1 - 1.9 7.9 5.4 5 6.5 0.0 3.7 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Ribosomal_S18 PF01084.15 EDN07116.1 - 5.7e-13 48.5 0.0 1.3e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 HTH_Tnp_Mu_1 PF02316.11 EDN07116.1 - 0.11 12.1 0.2 0.22 11.2 0.0 1.5 2 0 0 2 2 2 0 Mu DNA-binding domain PPR_2 PF13041.1 EDN07117.1 - 1.1e-12 47.6 0.2 0.034 14.1 0.0 6.2 7 0 0 7 7 7 4 PPR repeat family PPR_3 PF13812.1 EDN07117.1 - 1.3e-10 40.6 4.7 0.00027 20.9 0.0 6.2 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.15 EDN07117.1 - 6.8e-06 25.7 7.4 0.55 10.3 0.1 5.9 7 0 0 7 7 7 2 PPR repeat TPR_14 PF13428.1 EDN07117.1 - 0.022 15.3 0.7 2.8 8.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EDN07117.1 - 0.041 13.5 0.4 0.31 10.7 0.3 2.6 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.23 EDN07117.1 - 0.057 13.0 0.0 0.23 11.1 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat RPN7 PF10602.4 EDN07117.1 - 0.094 12.0 0.2 0.26 10.6 0.2 1.7 1 1 0 1 1 1 0 26S proteasome subunit RPN7 HTH_31 PF13560.1 EDN07117.1 - 0.099 12.8 0.3 0.72 10.0 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain BTAD PF03704.12 EDN07117.1 - 0.42 10.9 3.7 3.2 8.0 0.0 3.7 4 0 0 4 4 4 0 Bacterial transcriptional activator domain Ribosomal_S14 PF00253.16 EDN07118.1 - 4.6e-19 67.5 4.9 4.9e-19 67.4 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EDN07118.1 - 0.039 13.7 0.6 0.052 13.2 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DUF2318 PF10080.4 EDN07118.1 - 0.045 13.5 0.2 0.047 13.4 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) A2L_zn_ribbon PF08792.5 EDN07118.1 - 0.1 12.0 0.4 0.18 11.3 0.3 1.3 1 0 0 1 1 1 0 A2L zinc ribbon domain Prim_Zn_Ribbon PF08273.7 EDN07118.1 - 1 9.5 3.6 8.1 6.6 0.3 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase Toxin_17 PF08086.6 EDN07118.1 - 2.1 8.4 5.8 1.2 9.2 0.9 2.1 1 1 1 2 2 2 0 Ergtoxin family ELFV_dehydrog PF00208.16 EDN07119.1 - 3.3e-52 177.4 0.0 5.9e-52 176.6 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EDN07119.1 - 2.3e-17 61.8 0.1 5.4e-12 44.0 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EDN07119.1 - 0.0037 16.8 0.0 0.0094 15.5 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain TFIIIC_sub6 PF10419.4 EDN07122.1 - 1.4e-15 56.4 0.0 2.2e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit CDK2AP PF09806.4 EDN07122.1 - 0.047 13.9 1.8 0.079 13.1 1.3 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF946 PF06101.6 EDN07123.1 - 1e-12 46.8 1.3 1e-12 46.8 0.9 1.6 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) DUF1302 PF06980.6 EDN07123.1 - 0.026 13.1 0.1 0.038 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) Med15 PF09606.5 EDN07123.1 - 2.3 6.3 6.3 3.2 5.8 4.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Cupin_8 PF13621.1 EDN07124.1 - 1.5e-09 37.7 0.0 3.5e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EDN07124.1 - 1.5e-09 38.0 0.0 8.1e-09 35.7 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EDN07124.1 - 7.8e-08 31.8 4.2 7.8e-08 31.8 2.9 2.6 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.1 EDN07124.1 - 0.0068 15.6 2.0 0.034 13.4 1.4 2.3 1 0 0 1 1 1 1 PHD-finger Zn_clus PF00172.13 EDN07124.1 - 0.49 10.3 26.8 0.23 11.4 3.3 3.0 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 EDN07126.1 - 4.8e-19 67.7 0.3 8.4e-19 66.9 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN07126.1 - 5.8e-14 51.8 0.0 8.6e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN07126.1 - 1.6e-10 40.6 0.1 2.5e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3661 PF12400.3 EDN07127.1 - 9.6e-36 122.7 3.5 1.2e-35 122.3 2.4 1.1 1 0 0 1 1 1 1 Vaculolar membrane protein Hexokinase_1 PF00349.16 EDN07130.1 - 3.4e-70 235.5 0.6 9.6e-64 214.4 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_2 PF03727.11 EDN07130.1 - 5.4e-56 189.5 0.0 7e-37 126.9 0.0 2.2 1 1 1 2 2 2 2 Hexokinase Phospholip_A2_3 PF09056.6 EDN07130.1 - 0.16 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic phospholipase A2 SIR2 PF02146.12 EDN07131.1 - 2.2e-54 183.9 0.0 3.5e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family zf-dskA_traR PF01258.12 EDN07131.1 - 0.073 12.8 0.5 0.17 11.6 0.3 1.6 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger COG4 PF08318.7 EDN07132.1 - 1.1e-82 277.4 0.0 2.5e-53 180.9 0.0 2.5 2 1 1 3 3 3 2 COG4 transport protein Ammonium_transp PF00909.16 EDN07133.1 - 4e-113 377.9 29.9 4.6e-113 377.6 20.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family E1-E2_ATPase PF00122.15 EDN07134.1 - 1.9e-80 269.2 0.1 3.8e-80 268.2 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDN07134.1 - 9.6e-46 155.5 2.3 1e-45 155.4 0.1 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDN07134.1 - 3.7e-31 109.2 0.0 4.7e-30 105.6 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDN07134.1 - 2.4e-22 78.1 0.0 5.9e-22 76.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EDN07134.1 - 1.8e-15 57.6 0.0 5.4e-15 56.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN07134.1 - 3.5e-13 49.3 0.0 6.7e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EDN07134.1 - 4.8e-05 23.0 0.4 0.0005 19.7 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 EDN07135.1 - 5.7e-39 132.4 0.2 1.1e-38 131.6 0.0 1.6 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EDN07135.1 - 2.1e-08 33.2 0.0 4.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EDN07135.1 - 0.024 14.2 0.0 0.095 12.2 0.0 1.9 2 0 0 2 2 2 0 ScpA/B protein MFS_1 PF07690.11 EDN07136.1 - 1.7e-10 40.1 48.8 2.5e-10 39.5 15.8 3.4 2 1 1 3 3 3 3 Major Facilitator Superfamily Tyrosinase PF00264.15 EDN07137.1 - 1.8e-51 175.4 1.5 1.8e-51 175.4 1.0 1.6 2 0 0 2 2 2 1 Common central domain of tyrosinase Ribosomal_L35Ae PF01247.13 EDN07139.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L35Ae Zn_clus PF00172.13 EDN07140.1 - 0.016 15.0 9.2 0.016 15.0 6.4 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EDN07140.1 - 0.072 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 PAS fold Flavokinase PF01687.12 EDN07141.1 - 1e-25 90.0 0.0 2.5e-25 88.7 0.0 1.5 1 1 0 1 1 1 1 Riboflavin kinase DUF221 PF02714.10 EDN07144.1 - 9.4e-109 363.1 29.6 9.4e-109 363.1 20.5 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EDN07144.1 - 6.8e-45 152.4 0.8 6.8e-45 152.4 0.5 3.3 2 1 1 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EDN07144.1 - 1.9e-12 46.8 0.0 5.6e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EDN07144.1 - 4.6e-11 43.0 4.1 1.5e-06 28.6 1.4 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) MCM PF00493.18 EDN07146.1 - 6.4e-139 462.3 0.0 8.3e-139 461.9 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDN07146.1 - 6.1e-26 91.2 0.0 3.5e-25 88.8 0.0 2.3 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDN07146.1 - 5.1e-06 25.8 0.0 0.00019 20.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDN07146.1 - 1.1e-05 25.1 0.0 3.1e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EDN07146.1 - 0.0012 18.4 0.0 0.0045 16.5 0.0 2.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) VTC PF09359.5 EDN07147.1 - 9.6e-86 287.3 0.0 1.5e-85 286.7 0.0 1.2 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EDN07147.1 - 5.5e-30 105.0 3.1 1.6e-15 57.6 0.0 2.9 3 0 0 3 3 3 2 SPX domain DUF202 PF02656.10 EDN07147.1 - 5.9e-12 45.6 3.0 1.3e-11 44.5 2.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Ribophorin_I PF04597.9 EDN07148.1 - 3.6e-152 506.8 0.0 4.1e-152 506.6 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Pacs-1 PF10254.4 EDN07148.1 - 0.015 13.9 0.1 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Indigoidine_A PF04227.7 EDN07149.1 - 2.3e-106 355.2 0.6 3.3e-106 354.8 0.4 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EDN07149.1 - 1.9e-11 43.6 0.5 1.6e-05 24.1 0.1 2.4 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Ank_2 PF12796.2 EDN07150.1 - 1.5e-09 38.0 0.2 1e-06 28.9 0.1 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EDN07150.1 - 0.0037 16.9 0.1 0.02 14.6 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EDN07150.1 - 0.004 17.6 0.1 3.1 8.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN07150.1 - 0.0065 16.6 0.9 3.9 7.8 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN07150.1 - 0.081 13.2 0.4 27 5.3 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat Ferritin_2 PF13668.1 EDN07151.1 - 6.6e-41 139.4 0.2 8.8e-41 139.0 0.2 1.2 1 0 0 1 1 1 1 Ferritin-like domain Band_7 PF01145.20 EDN07152.1 - 1.4e-18 67.4 2.1 2.1e-18 66.8 1.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family CSTF2_hinge PF14327.1 EDN07153.1 - 2.1e-29 101.4 1.8 2.1e-29 101.4 1.3 3.2 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 EDN07153.1 - 2e-15 55.7 7.1 2e-15 55.7 4.9 2.4 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.17 EDN07153.1 - 2.8e-15 55.6 0.0 4.9e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN07153.1 - 9.4e-13 47.9 0.0 1.8e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN07153.1 - 5.1e-08 32.6 0.0 7.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNF2_N PF00176.18 EDN07154.1 - 2e-14 53.0 0.0 5e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.12 EDN07154.1 - 1.3e-13 50.8 0.0 6.4e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Fmp27_WPPW PF10359.4 EDN07154.1 - 0.041 12.3 2.5 0.066 11.6 1.8 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ResIII PF04851.10 EDN07154.1 - 0.12 12.2 0.7 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 EDN07155.1 - 6.2e-05 22.6 6.4 0.00017 21.2 4.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.26 EDN07155.1 - 0.0013 18.5 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EDN07155.1 - 0.0019 18.1 6.9 0.0042 17.0 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN07155.1 - 0.0065 16.1 6.9 0.015 14.9 4.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN07155.1 - 0.008 15.9 6.2 0.021 14.6 4.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EDN07155.1 - 0.73 9.7 6.9 3.1 7.7 4.8 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EDN07155.1 - 3.5 7.4 7.3 21 4.9 5.1 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein 2Fe-2S_thioredx PF01257.14 EDN07156.1 - 2.9e-59 198.8 0.1 3.5e-59 198.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Sua5_yciO_yrdC PF01300.13 EDN07158.1 - 9.7e-54 181.3 0.0 1.9e-53 180.4 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EDN07158.1 - 2.1e-25 89.1 0.0 1.7e-24 86.2 0.0 2.3 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding DUF3441 PF11923.3 EDN07159.1 - 2.9e-41 139.5 2.1 3e-41 139.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EDN07159.1 - 3.2e-29 101.8 8.9 3.6e-21 75.2 0.0 2.8 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EDN07159.1 - 1.2e-15 57.1 0.0 2.8e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Clat_adaptor_s PF01217.15 EDN07160.1 - 5.9e-13 48.7 0.0 8.9e-12 44.9 0.1 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain DUF1515 PF07439.6 EDN07161.1 - 0.0048 16.6 4.6 0.0048 16.6 3.2 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1515) Reo_sigmaC PF04582.7 EDN07161.1 - 0.053 12.6 1.8 0.092 11.9 1.2 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4613 PF15390.1 EDN07161.1 - 0.97 7.5 12.9 1.6 6.8 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) MIF4G_like_2 PF09090.6 EDN07161.1 - 1.3 8.2 9.9 1.2 8.3 5.6 1.7 1 1 0 1 1 1 0 MIF4G like DUF948 PF06103.6 EDN07161.1 - 2.7 7.9 5.0 0.85 9.5 1.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Ribosomal_L7Ae PF01248.21 EDN07163.1 - 4.2e-26 90.2 0.0 4.9e-26 90.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.13 EDN07164.1 - 1.5e-30 105.6 0.1 2.1e-30 105.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e TPR_1 PF00515.23 EDN07164.1 - 0.07 12.7 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Lambda_CIII PF02061.11 EDN07165.1 - 0.098 12.6 0.0 16 5.5 0.0 2.7 2 0 0 2 2 2 0 Lambda Phage CIII OB_NTP_bind PF07717.11 EDN07166.1 - 9.1e-20 70.6 0.0 2e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EDN07166.1 - 2e-18 66.3 0.1 6.1e-18 64.7 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDN07166.1 - 9.7e-11 41.3 0.0 3.3e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN07166.1 - 2.8e-05 23.6 0.0 0.00016 21.2 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_29 PF13555.1 EDN07166.1 - 0.0031 17.0 0.0 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EDN07166.1 - 0.0034 17.6 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 ABC transporter KaiC PF06745.8 EDN07166.1 - 0.019 14.0 0.0 0.058 12.5 0.0 1.8 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 EDN07166.1 - 0.021 14.9 0.2 0.13 12.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EDN07166.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Abhydrolase_6 PF12697.2 EDN07168.1 - 9.4e-18 64.9 0.0 1.3e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EDN07168.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Complex1_LYR PF05347.10 EDN07170.1 - 3.6e-09 36.2 0.1 5.8e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDN07170.1 - 2e-08 34.3 0.0 2.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EDN07170.1 - 6.4e-05 23.3 0.1 9.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Methyltransf_26 PF13659.1 EDN07171.1 - 5.1e-17 61.9 0.0 7.1e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN07171.1 - 0.0086 16.5 0.1 0.2 12.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EDN07171.1 - 0.014 14.7 0.1 0.6 9.4 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase small domain LSM PF01423.17 EDN07172.1 - 1.9e-16 59.3 0.0 2.4e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDN07172.1 - 0.00047 20.0 0.0 0.00065 19.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2763 PF10961.3 EDN07172.1 - 0.049 14.0 6.2 0.073 13.4 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) HlyD_3 PF13437.1 EDN07172.1 - 0.096 13.0 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein API5 PF05918.6 EDN07172.1 - 5 5.4 12.8 6.7 5.0 8.9 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) GTP_EFTU PF00009.22 EDN07173.1 - 1.7e-08 34.1 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EDN07173.1 - 0.26 10.7 0.3 4.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DDE_1 PF03184.14 EDN07174.1 - 1.8e-51 174.3 0.0 4.6e-51 173.0 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease zf-CCHC_4 PF14392.1 EDN07174.1 - 0.013 15.1 0.5 0.027 14.1 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.1 EDN07174.1 - 0.025 14.2 0.3 0.3 10.7 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EDN07174.1 - 0.19 11.7 1.0 0.32 11.0 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 EDN07175.1 - 1.8e-26 92.8 0.0 3.4e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN07175.1 - 4.5e-20 71.9 0.1 1.8e-19 70.0 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EDN07175.1 - 1.6e-13 50.0 2.5 2.3e-13 49.5 0.7 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EDN07175.1 - 0.035 13.5 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger Mtf2_C PF14061.1 EDN07175.1 - 0.049 13.5 0.6 0.16 11.8 0.1 2.0 1 1 1 2 2 2 0 Polycomb-like MTF2 factor 2 zf-C2H2 PF00096.21 EDN07177.1 - 8e-06 25.8 3.3 0.069 13.5 0.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN07177.1 - 1.8e-05 24.7 4.0 0.0077 16.4 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger UPF0547 PF10571.4 EDN07177.1 - 0.003 17.2 0.3 0.006 16.2 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zf-C2H2_6 PF13912.1 EDN07177.1 - 0.074 12.9 4.3 5.8 6.9 0.1 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EDN07177.1 - 1.1 9.1 4.4 0.39 10.5 0.9 1.9 2 1 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.1 EDN07177.1 - 1.4 9.3 5.4 0.35 11.2 1.1 2.0 2 1 0 2 2 2 0 Zinc-finger double domain Pkr1 PF08636.5 EDN07178.1 - 1.8e-33 114.4 5.9 2.2e-33 114.1 4.1 1.1 1 0 0 1 1 1 1 ER protein Pkr1 CXCL17 PF15211.1 EDN07179.1 - 0.1 12.9 0.0 0.33 11.3 0.0 1.7 2 0 0 2 2 2 0 VEGF co-regulated chemokine 1 DUF989 PF06181.6 EDN07179.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF989) APC2 PF08672.6 EDN07180.1 - 2.9e-23 81.8 0.0 4e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 DNA_pol3_gamma3 PF12169.3 EDN07180.1 - 0.076 12.7 0.2 0.14 11.9 0.1 1.5 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III F-box-like PF12937.2 EDN07181.1 - 9.4e-08 31.6 0.3 1.9e-07 30.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN07181.1 - 0.0017 17.9 0.1 0.0045 16.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain TPR_11 PF13414.1 EDN07181.1 - 0.055 13.1 0.2 0.096 12.3 0.1 1.3 1 0 0 1 1 1 0 TPR repeat Cwf_Cwc_15 PF04889.7 EDN07184.1 - 2.3 7.8 12.3 2.4 7.7 8.5 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ank_2 PF12796.2 EDN07186.1 - 1.7e-15 57.0 0.3 1.3e-07 31.8 0.0 4.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDN07186.1 - 7.2e-14 51.4 1.0 0.0055 16.9 0.0 6.4 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN07186.1 - 1.5e-12 47.6 0.3 3.3e-05 24.2 0.0 5.4 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EDN07186.1 - 5.6e-07 29.0 1.1 0.008 15.9 0.0 5.8 6 1 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.1 EDN07186.1 - 8e-07 28.7 1.5 0.08 13.2 0.0 6.5 7 0 0 7 7 7 1 Ankyrin repeat KAR9 PF08580.5 EDN07187.1 - 8.9e-115 384.5 17.6 8.9e-115 384.5 12.2 3.0 2 1 0 2 2 2 1 Yeast cortical protein KAR9 PhoU_div PF01865.11 EDN07187.1 - 0.0099 15.0 0.2 0.0099 15.0 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function DUF47 DUF3198 PF11433.3 EDN07187.1 - 0.019 14.8 0.2 0.12 12.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) FemAB PF02388.11 EDN07187.1 - 0.13 10.9 0.2 0.2 10.3 0.2 1.2 1 0 0 1 1 1 0 FemAB family MT0933_antitox PF14013.1 EDN07187.1 - 0.16 12.1 1.1 1.2 9.2 0.3 2.3 2 0 0 2 2 2 0 MT0933-like antitoxin protein CpeT PF06206.6 EDN07188.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) Med25_SD1 PF11235.3 EDN07188.1 - 9.6 6.4 10.6 4.2 7.6 3.4 2.4 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 Acylphosphatase PF00708.13 EDN07189.1 - 7.2e-28 96.5 0.1 7.8e-28 96.4 0.0 1.0 1 0 0 1 1 1 1 Acylphosphatase AOX PF01786.12 EDN07190.1 - 1.6e-92 308.6 0.1 2e-92 308.2 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase MBOAT PF03062.14 EDN07191.1 - 6.5e-31 107.6 15.7 7.3e-25 87.7 4.8 2.5 1 1 1 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family PufQ PF05398.6 EDN07191.1 - 0.001 19.0 0.8 0.89 9.6 0.1 2.5 2 0 0 2 2 2 2 PufQ cytochrome subunit zf-HIT PF04438.11 EDN07192.1 - 2.2e-10 40.0 8.4 3.3e-10 39.4 5.9 1.3 1 0 0 1 1 1 1 HIT zinc finger Mucin PF01456.12 EDN07192.1 - 4.3 7.1 18.1 9.7 5.9 12.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF566 PF04484.7 EDN07192.1 - 9.1 5.6 13.4 13 5.1 9.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Dopey_N PF04118.9 EDN07194.1 - 2.3e-122 407.5 0.1 1.5e-121 404.9 0.0 2.4 3 0 0 3 3 3 1 Dopey, N-terminal Mon1 PF03164.9 EDN07195.1 - 2e-90 303.4 0.0 3.6e-74 249.8 0.0 2.0 1 1 1 2 2 2 2 Trafficking protein Mon1 DEAD PF00270.24 EDN07196.1 - 3.7e-21 75.3 0.0 1.5e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN07196.1 - 4.1e-20 71.4 0.0 1.5e-19 69.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RQC PF09382.5 EDN07196.1 - 1.4e-16 60.0 0.0 4.2e-16 58.5 0.0 1.9 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 EDN07196.1 - 2.6e-10 39.8 0.6 9.2e-10 38.1 0.0 2.3 3 0 0 3 3 3 1 HRDC domain ResIII PF04851.10 EDN07196.1 - 0.017 14.9 0.0 0.052 13.3 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EDN07196.1 - 0.29 10.3 2.0 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 SecA DEAD-like domain DUF4110 PF13422.1 EDN07197.1 - 3.8e-31 106.7 0.5 3.8e-31 106.7 0.3 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 EDN07197.1 - 1.6e-13 50.4 10.5 0.00011 22.2 0.0 5.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EDN07197.1 - 3e-12 45.7 1.1 2.4e-06 27.0 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 EDN07197.1 - 1.6e-11 43.7 10.8 0.0011 18.6 0.0 5.1 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EDN07197.1 - 3.1e-11 42.6 0.5 1.5e-06 27.6 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 EDN07197.1 - 3.4e-11 42.8 0.9 0.00017 21.5 0.1 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 EDN07197.1 - 6.2e-11 42.0 1.3 5.4e-06 26.2 0.0 4.4 5 0 0 5 5 5 2 Kelch motif Pyridoxal_deC PF00282.14 EDN07198.1 - 1.2e-15 56.8 0.0 2.9e-15 55.6 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain MR_MLE_C PF13378.1 EDN07198.1 - 0.0074 16.2 1.1 0.72 9.8 0.0 3.0 3 0 0 3 3 3 1 Enolase C-terminal domain-like Beta_elim_lyase PF01212.16 EDN07198.1 - 0.0078 15.3 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase RWP-RK PF02042.10 EDN07198.1 - 0.014 15.2 0.0 0.047 13.5 0.0 1.8 2 0 0 2 2 2 0 RWP-RK domain Aminotran_1_2 PF00155.16 EDN07198.1 - 0.03 13.2 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Abhydrolase_5 PF12695.2 EDN07199.1 - 0.0003 20.5 0.0 0.0013 18.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN07199.1 - 0.015 15.1 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN07199.1 - 0.041 13.4 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold CENP-K PF11802.3 EDN07200.1 - 0.00017 20.9 4.1 0.11 11.6 0.0 2.5 2 1 1 3 3 3 1 Centromere-associated protein K DUF3373 PF11853.3 EDN07200.1 - 0.023 13.2 1.5 0.033 12.7 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) IFT46_B_C PF12317.3 EDN07200.1 - 0.21 10.9 1.1 3.3 7.0 0.1 2.4 2 1 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal P4Ha_N PF08336.6 EDN07200.1 - 2.1 8.1 8.1 0.31 10.8 1.3 2.5 1 1 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fzo_mitofusin PF04799.8 EDN07200.1 - 3 7.1 8.9 3.1 7.1 2.5 2.6 2 1 0 2 2 2 0 fzo-like conserved region TMPIT PF07851.8 EDN07200.1 - 9.2 5.2 8.9 0.43 9.6 0.2 2.0 1 1 1 2 2 2 0 TMPIT-like protein KH_1 PF00013.24 EDN07201.1 - 1.1e-35 121.0 3.3 6.5e-12 44.9 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EDN07201.1 - 1.4e-29 101.2 9.8 1.8e-10 40.2 0.9 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EDN07201.1 - 3.8e-10 39.1 2.7 0.012 15.1 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EDN07201.1 - 0.00041 20.0 5.3 1.1 9.1 0.0 3.6 3 0 0 3 3 3 3 NusA-like KH domain KH_4 PF13083.1 EDN07201.1 - 0.0042 16.6 0.2 3.4 7.3 0.0 3.1 3 0 0 3 3 3 2 KH domain ABM PF03992.11 EDN07202.1 - 0.0053 16.7 0.5 0.46 10.5 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Fungal_trans PF04082.13 EDN07204.1 - 2.4e-14 52.8 0.1 5.2e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN07204.1 - 6.4e-09 35.5 8.9 1.1e-08 34.8 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EDN07205.1 - 0.0029 17.4 0.2 2.3 8.2 0.1 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat DASH_Spc34 PF08657.5 EDN07205.1 - 0.011 15.3 1.0 0.021 14.4 0.2 1.8 1 1 0 1 1 1 0 DASH complex subunit Spc34 Phage_HK97_TLTM PF06120.6 EDN07205.1 - 0.012 14.9 2.1 0.022 14.1 1.5 1.3 1 0 0 1 1 1 0 Tail length tape measure protein Baculo_PEP_C PF04513.7 EDN07205.1 - 0.17 11.7 6.7 0.15 11.8 3.3 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DLIC PF05783.6 EDN07205.1 - 0.53 8.8 2.0 1 7.9 1.4 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) CorA PF01544.13 EDN07205.1 - 1.2 8.1 3.7 4.5 6.2 1.8 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4618 PF15397.1 EDN07205.1 - 2.3 7.5 8.8 18 4.5 6.1 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Proteasome PF00227.21 EDN07206.1 - 4.5e-44 150.0 0.0 5.4e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EDN07206.1 - 2.3e-15 55.5 0.0 5e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal RVT_2 PF07727.9 EDN07208.1 - 2.2e-58 197.1 0.0 3.2e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN07208.1 - 2.3e-15 56.7 0.0 5.9e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 EDN07208.1 - 0.00023 20.9 4.1 0.00047 19.9 2.8 1.6 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.1 EDN07208.1 - 0.0018 17.8 0.0 0.0057 16.2 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 EDN07208.1 - 0.0061 16.3 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 EDN07209.1 - 8.1e-05 22.3 2.3 0.00015 21.4 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.1 EDN07209.1 - 0.00018 21.0 0.1 0.00054 19.5 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 EDN07209.1 - 0.0065 16.2 0.0 0.015 15.0 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-C4pol PF14260.1 EDN07209.1 - 0.25 11.3 3.1 0.57 10.2 1.2 2.1 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Peptidase_M3 PF01432.15 EDN07211.1 - 1.6e-123 413.1 0.0 1.9e-123 412.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EDN07211.1 - 0.062 12.6 0.2 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like ApoO PF09769.4 EDN07212.1 - 2.4e-49 167.0 0.4 1.1e-48 164.9 0.1 1.8 2 0 0 2 2 2 1 Apolipoprotein O SBF PF01758.11 EDN07212.1 - 0.094 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Sodium Bile acid symporter family GRASP55_65 PF04495.9 EDN07213.1 - 7.5e-41 139.3 0.0 4.6e-40 136.8 0.0 1.9 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain Methyltransf_15 PF09445.5 EDN07214.1 - 4.4e-49 166.1 0.0 5.8e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 EDN07214.1 - 9.7e-11 41.6 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 EDN07214.1 - 9.7e-11 41.5 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EDN07214.1 - 2.2e-10 40.5 0.0 3.2e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN07214.1 - 1.4e-07 32.0 0.0 1.8e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EDN07214.1 - 1.7e-05 24.3 0.0 2.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 EDN07214.1 - 0.00052 19.6 0.0 0.00062 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.14 EDN07214.1 - 0.0088 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family Methyltransf_3 PF01596.12 EDN07214.1 - 0.018 14.0 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.9 EDN07214.1 - 0.018 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DNA_methylase PF00145.12 EDN07214.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase DUF3591 PF12157.3 EDN07215.1 - 7.7e-188 624.5 5.9 5.8e-187 621.6 4.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EDN07215.1 - 0.0038 16.8 1.2 0.0086 15.7 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EDN07215.1 - 0.014 15.3 0.9 0.025 14.5 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.20 EDN07216.1 - 2.8e-36 125.0 0.2 3.2e-19 69.0 0.0 3.3 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07216.1 - 1.7e-13 50.2 0.0 2.9e-06 26.5 0.0 3.3 2 1 1 3 3 3 3 Protein tyrosine kinase Pkinase_C PF00433.19 EDN07216.1 - 0.054 14.0 0.4 0.38 11.3 0.3 2.3 1 1 0 1 1 1 0 Protein kinase C terminal domain FKBP_C PF00254.23 EDN07217.1 - 7.8e-14 51.4 0.2 6.1e-13 48.5 0.0 2.6 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase CENP-T PF15511.1 EDN07217.1 - 1.5 8.0 33.9 0.41 9.8 7.3 2.2 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T IMS PF00817.15 EDN07218.1 - 1.1e-41 142.0 0.0 2.1e-41 141.1 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EDN07218.1 - 4.7e-18 65.3 0.0 1.1e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EDN07218.1 - 3.8e-11 42.8 6.7 0.0001 22.1 0.3 3.8 4 0 0 4 4 4 2 Domain of unknown function (DUF4414) BRCT PF00533.21 EDN07218.1 - 4.7e-06 26.6 0.0 1.4e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 EDN07218.1 - 1.4e-05 24.8 0.0 7.3e-05 22.5 0.0 2.3 1 0 0 1 1 1 1 IMS family HHH motif PTCB-BRCT PF12738.2 EDN07218.1 - 0.00033 20.4 0.0 0.0011 18.8 0.0 2.0 1 0 0 1 1 1 1 twin BRCT domain HHH_5 PF14520.1 EDN07218.1 - 0.053 13.7 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF4066 PF13278.1 EDN07219.1 - 3e-30 104.6 0.0 3.7e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EDN07219.1 - 4e-12 45.8 0.0 6.4e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EDN07219.1 - 0.0084 15.5 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Aminotran_1_2 PF00155.16 EDN07220.1 - 6.8e-70 235.8 0.0 8.1e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II BCS1_N PF08740.6 EDN07220.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 BCS1 N terminal MSC PF09402.5 EDN07222.1 - 7.3e-98 327.3 0.0 9.4e-98 326.9 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EDN07222.1 - 5.3e-17 61.0 1.4 1.1e-15 56.8 0.1 2.8 3 0 0 3 3 3 1 HeH/LEM domain DUF3637 PF12337.3 EDN07222.1 - 0.021 14.8 0.8 0.047 13.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3637) DUF3350 PF11830.3 EDN07222.1 - 0.17 11.9 3.1 0.5 10.4 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3350) PP2C PF00481.16 EDN07223.1 - 5.2e-55 186.5 0.0 7.6e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EDN07223.1 - 1.9e-28 97.5 31.6 4.8e-07 29.2 0.4 8.6 6 3 0 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDN07223.1 - 2.4e-19 68.8 31.1 1.6e-07 30.9 0.8 5.9 4 2 1 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 EDN07223.1 - 5.5e-17 59.1 27.5 0.19 11.9 0.1 11.8 11 1 0 11 11 11 6 Leucine Rich Repeat Guanylate_cyc PF00211.15 EDN07223.1 - 1.3e-11 44.1 0.0 2.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_7 PF13504.1 EDN07223.1 - 1.3e-09 36.6 30.6 3 8.4 0.0 12.9 13 0 0 13 13 13 1 Leucine rich repeat LRR_6 PF13516.1 EDN07223.1 - 5e-08 32.2 24.6 1.5 9.1 0.0 10.9 11 0 0 11 11 11 2 Leucine Rich repeat LRR_5 PF13306.1 EDN07223.1 - 0.0024 17.5 0.7 0.011 15.4 0.6 2.0 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) PP2C_2 PF13672.1 EDN07223.1 - 0.0029 17.0 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.1 EDN07223.1 - 0.0051 16.3 1.6 0.35 10.4 0.1 2.3 2 0 0 2 2 2 1 Leucine-rich repeat Dynamin_M PF01031.15 EDN07223.1 - 0.087 11.5 0.0 0.21 10.2 0.0 1.6 2 0 0 2 2 2 0 Dynamin central region Herpes_LMP2 PF07415.6 EDN07224.1 - 0.93 8.0 2.0 1.6 7.2 1.4 1.4 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Calcipressin PF04847.7 EDN07225.1 - 7.7e-30 103.8 0.0 1.4e-29 103.0 0.0 1.4 1 1 0 1 1 1 1 Calcipressin Uds1 PF15456.1 EDN07226.1 - 7.4e-31 106.7 3.2 1.5e-30 105.7 2.2 1.5 1 0 0 1 1 1 1 Up-regulated During Septation GrpE PF01025.14 EDN07227.1 - 2.1e-43 147.7 4.3 2.9e-43 147.2 3.0 1.2 1 0 0 1 1 1 1 GrpE AAA_32 PF13654.1 EDN07227.1 - 0.047 12.3 1.9 0.07 11.7 1.3 1.2 1 0 0 1 1 1 0 AAA domain Peptidase_S49 PF01343.13 EDN07227.1 - 0.05 13.3 0.6 0.077 12.7 0.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 Focal_AT PF03623.8 EDN07227.1 - 0.051 13.0 0.1 0.38 10.2 0.0 2.0 1 1 1 2 2 2 0 Focal adhesion targeting region DUF2277 PF10041.4 EDN07227.1 - 0.069 13.1 0.3 0.18 11.7 0.2 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2277) IncA PF04156.9 EDN07227.1 - 0.68 9.5 3.3 1.1 8.8 2.3 1.3 1 0 0 1 1 1 0 IncA protein tRNA-synt_2d PF01409.15 EDN07228.1 - 8.5e-48 162.6 0.1 5.2e-26 91.3 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EDN07228.1 - 2.1e-24 85.5 0.0 4.6e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain EFP_N PF08207.7 EDN07228.1 - 0.081 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Mito_carr PF00153.22 EDN07229.1 - 7.7e-62 205.0 0.0 1.3e-19 69.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein COX6B PF02297.12 EDN07230.1 - 4e-19 68.3 4.8 4.8e-19 68.1 3.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EDN07230.1 - 0.0014 17.9 0.5 0.0023 17.2 0.4 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain ketoacyl-synt PF00109.21 EDN07230.1 - 0.16 11.4 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain UPF0203 PF05254.7 EDN07230.1 - 2.7 7.9 5.9 2.1 8.2 0.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) B12D PF06522.6 EDN07231.1 - 0.00018 21.1 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF1179 PF06678.6 EDN07231.1 - 0.18 12.1 0.7 1.3 9.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1179) RRM_1 PF00076.17 EDN07232.1 - 9.1e-17 60.4 0.0 1.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN07232.1 - 6.8e-12 45.1 0.0 1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN07232.1 - 3.5e-09 36.3 0.0 4.9e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDN07232.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif WD40 PF00400.27 EDN07233.1 - 1.5e-16 59.5 9.0 0.00015 21.5 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 EDN07233.1 - 7.3e-13 48.5 0.0 2.1e-12 47.0 0.0 1.9 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 EDN07233.1 - 0.11 12.2 0.2 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 Prp18 domain Pex14_N PF04695.8 EDN07235.1 - 2.5e-28 98.8 2.6 3e-28 98.5 0.1 2.2 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAPA-1 PF04795.7 EDN07236.1 - 2.4e-30 105.0 2.4 9.7e-30 103.1 1.7 2.1 1 0 0 1 1 1 1 PAPA-1-like conserved region Mus7 PF09462.5 EDN07238.1 - 8.5e-176 586.4 7.9 1.2e-175 585.9 5.5 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family DUF4050 PF13259.1 EDN07239.1 - 3.2e-41 140.0 0.1 1.1e-40 138.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) CDC27 PF09507.5 EDN07239.1 - 0.036 13.2 1.8 0.079 12.1 1.2 1.5 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA PF00004.24 EDN07240.1 - 2.3e-38 131.3 0.0 2.2e-37 128.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN07240.1 - 2.1e-05 24.6 0.1 0.00052 20.1 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN07240.1 - 3.1e-05 24.0 0.7 0.0038 17.2 0.1 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EDN07240.1 - 7.1e-05 22.5 0.2 0.00067 19.3 0.0 2.6 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EDN07240.1 - 0.00017 21.4 0.0 0.0026 17.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDN07240.1 - 0.00025 20.1 0.0 0.00056 19.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EDN07240.1 - 0.00044 19.0 0.0 0.00099 17.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EDN07240.1 - 0.0016 18.1 0.2 0.008 15.9 0.1 2.2 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EDN07240.1 - 0.0017 19.1 0.0 0.0094 16.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EDN07240.1 - 0.002 18.0 0.0 0.0055 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EDN07240.1 - 0.0027 16.8 0.1 0.0074 15.4 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EDN07240.1 - 0.0029 17.0 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EDN07240.1 - 0.0048 16.7 0.0 0.027 14.3 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EDN07240.1 - 0.0055 16.1 0.2 2.8 7.2 0.0 2.4 1 1 1 2 2 2 2 AAA-like domain SHQ1 PF04925.10 EDN07240.1 - 0.011 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 SHQ1 protein AAA_25 PF13481.1 EDN07240.1 - 0.026 13.9 0.2 0.23 10.8 0.1 2.5 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 EDN07240.1 - 0.026 14.6 0.0 0.076 13.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EDN07240.1 - 0.059 12.9 1.2 0.092 12.3 0.2 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EDN07240.1 - 0.082 13.2 0.7 0.46 10.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain IPT PF01745.11 EDN07240.1 - 0.084 12.0 0.0 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 Isopentenyl transferase Sigma54_activat PF00158.21 EDN07240.1 - 0.094 12.1 0.1 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 EDN07240.1 - 0.097 12.3 0.1 0.29 10.7 0.1 1.8 2 0 0 2 2 1 0 NACHT domain Parvo_NS1 PF01057.12 EDN07240.1 - 0.21 10.4 0.0 0.36 9.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 LIM_bind PF01803.11 EDN07242.1 - 6.7e-68 228.3 0.1 6.7e-68 228.3 0.0 4.9 3 2 2 5 5 5 1 LIM-domain binding protein CDC45 PF02724.9 EDN07242.1 - 0.098 10.6 15.6 0.16 9.9 10.8 1.4 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 EDN07242.1 - 0.56 7.8 18.8 0.8 7.3 13.0 1.2 1 0 0 1 1 1 0 Ycf1 Herpes_env PF01673.13 EDN07242.1 - 2.7 6.4 17.8 5 5.5 12.3 1.4 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein LicD PF04991.8 EDN07242.1 - 9.7 6.2 7.4 8.3 6.4 3.5 1.9 2 0 0 2 2 2 0 LicD family cobW PF02492.14 EDN07244.1 - 2.3e-35 121.6 0.0 2.8e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EDN07244.1 - 3.6e-05 22.6 0.0 0.024 13.4 0.0 2.0 2 0 0 2 2 2 2 ArgK protein AAA_25 PF13481.1 EDN07244.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EDN07244.1 - 0.023 15.0 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EDN07244.1 - 0.032 14.1 0.0 0.087 12.7 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 EDN07244.1 - 0.038 14.7 0.0 0.067 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EDN07244.1 - 0.047 13.3 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 EDN07244.1 - 0.075 12.4 0.0 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA12 PF10443.4 EDN07244.1 - 0.14 10.5 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein BING4CT PF08149.6 EDN07245.1 - 2.8e-39 132.4 0.0 5.1e-36 122.0 0.0 2.8 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 EDN07245.1 - 8.6e-05 22.2 0.0 0.067 13.1 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF663 PF04950.7 EDN07246.1 - 3.5e-96 321.6 0.0 4.8e-96 321.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EDN07246.1 - 1.6e-23 82.0 0.0 3.6e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DUF726 PF05277.7 EDN07247.1 - 3.7e-119 397.6 1.2 5.4e-119 397.1 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 EDN07247.1 - 2.3e-06 28.0 0.0 0.00022 21.5 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 EDN07247.1 - 1.5e-05 24.9 0.4 4.4e-05 23.4 0.0 1.8 1 1 0 2 2 2 1 Alpha/beta hydrolase family Glu-tRNAGln PF02686.10 EDN07247.1 - 0.00079 19.1 0.3 0.0022 17.7 0.2 1.7 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Abhydrolase_5 PF12695.2 EDN07247.1 - 0.0041 16.8 1.1 0.0079 15.9 0.0 1.9 1 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN07247.1 - 0.021 14.4 0.0 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1469 PF07332.6 EDN07247.1 - 0.075 12.7 7.5 0.21 11.3 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) SNAP PF14938.1 EDN07248.1 - 4.3e-114 380.4 15.5 4.8e-114 380.2 10.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EDN07248.1 - 1.7e-07 31.0 14.7 0.00075 19.3 4.2 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDN07248.1 - 0.00025 21.6 14.2 0.089 13.4 1.9 3.6 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDN07248.1 - 0.0057 16.4 16.7 1.1 9.2 0.1 6.6 4 2 3 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDN07248.1 - 0.036 13.6 18.6 0.72 9.5 2.5 4.1 1 1 3 4 4 4 0 TPR repeat DFF40 PF09230.5 EDN07248.1 - 0.072 12.4 0.1 0.14 11.5 0.1 1.5 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa TPR_8 PF13181.1 EDN07248.1 - 0.13 12.0 14.1 0.99 9.3 0.4 5.3 3 2 1 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.7 EDN07248.1 - 0.21 12.2 8.3 5.7 7.7 0.3 4.6 2 1 2 4 4 4 0 Sel1 repeat TPR_6 PF13174.1 EDN07248.1 - 0.34 11.4 16.5 7.2 7.3 0.1 5.9 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDN07248.1 - 0.39 10.4 16.9 3 7.6 0.4 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat NSF PF02071.15 EDN07248.1 - 2.6 9.0 19.1 3.6 8.5 0.6 6.7 7 0 0 7 7 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_3 PF07720.7 EDN07248.1 - 3.5 7.5 11.7 1.6 8.6 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank PF00023.25 EDN07249.1 - 2.3e-09 36.5 0.0 5.3e-07 29.1 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EDN07249.1 - 2.9e-06 27.5 0.1 8.1e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EDN07249.1 - 0.00024 21.0 0.0 0.0031 17.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Torsin PF06309.6 EDN07249.1 - 0.00066 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Torsin Ank_4 PF13637.1 EDN07249.1 - 0.0026 18.2 0.0 0.015 15.8 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) AAA PF00004.24 EDN07249.1 - 0.011 15.9 0.0 0.06 13.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4556 PF15094.1 EDN07249.1 - 0.032 13.8 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) Ank_5 PF13857.1 EDN07249.1 - 0.065 13.5 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Pyr_redox_3 PF13738.1 EDN07254.1 - 0.0047 17.0 0.0 0.0077 16.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sec62 PF03839.11 EDN07256.1 - 2.8e-52 177.3 0.2 2.8e-52 177.3 0.2 1.7 2 0 0 2 2 2 1 Translocation protein Sec62 SinI PF08671.5 EDN07256.1 - 0.032 13.6 0.0 4.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Anti-repressor SinI APC_CDC26 PF10471.4 EDN07256.1 - 0.76 10.5 9.8 0.25 12.1 0.7 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Carn_acyltransf PF00755.15 EDN07259.1 - 5.7e-179 596.0 0.1 6.5e-179 595.8 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rxt3 PF08642.5 EDN07260.1 - 6.7e-26 90.7 0.0 1.1e-24 86.8 0.0 2.3 1 1 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EDN07260.1 - 0.00048 20.0 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 LCCL domain DUF3560 PF12083.3 EDN07261.1 - 0.14 12.1 1.1 0.19 11.7 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) FlxA PF14282.1 EDN07261.1 - 0.15 12.0 3.5 0.17 11.8 2.5 1.1 1 0 0 1 1 1 0 FlxA-like protein DUF4140 PF13600.1 EDN07261.1 - 0.17 12.3 2.6 0.21 12.0 1.8 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3435 PF11917.3 EDN07262.1 - 9.8e-128 426.4 0.5 1.2e-127 426.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Peptidase_M17_N PF02789.12 EDN07263.1 - 0.17 11.6 0.1 0.85 9.3 0.1 2.0 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain DEAD PF00270.24 EDN07265.1 - 2.4e-11 43.4 0.0 8.5e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN07265.1 - 7.7e-05 22.6 0.0 0.0011 18.8 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CLN3 PF02487.12 EDN07268.1 - 3.5e-83 279.6 22.6 1.8e-79 267.4 15.7 3.0 1 1 0 1 1 1 1 CLN3 protein F-box PF00646.28 EDN07268.1 - 8.2e-06 25.3 0.0 1.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN07268.1 - 9e-06 25.3 0.1 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like Abhydrolase_3 PF07859.8 EDN07269.1 - 1.4e-36 126.1 0.0 2.1e-27 96.0 0.0 3.1 4 0 0 4 4 4 2 alpha/beta hydrolase fold Aminotran_3 PF00202.16 EDN07270.1 - 4.3e-92 308.5 0.0 5.4e-92 308.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EDN07270.1 - 4.5e-06 25.8 0.0 7.7e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1674 PF07896.7 EDN07271.1 - 5e-08 33.0 1.2 1.2e-07 31.8 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) HMGL-like PF00682.14 EDN07272.1 - 1.8e-37 129.2 0.1 2.3e-36 125.6 0.1 2.0 1 1 0 1 1 1 1 HMGL-like Pkinase PF00069.20 EDN07274.1 - 9.1e-21 74.1 0.0 8e-18 64.5 0.0 2.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07274.1 - 0.0012 17.9 0.0 0.32 10.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Diphthamide_syn PF01866.12 EDN07275.1 - 5.4e-112 373.9 0.0 6.4e-112 373.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Bromodomain PF00439.20 EDN07276.1 - 1.2e-14 53.9 0.0 2.2e-14 53.0 0.0 1.5 1 1 0 1 1 1 1 Bromodomain AIRC PF00731.15 EDN07278.1 - 3.9e-58 194.9 1.2 9.4e-58 193.7 0.8 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EDN07278.1 - 9e-55 184.6 0.0 1.5e-54 183.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EDN07278.1 - 3.2e-11 43.3 0.0 6.9e-11 42.2 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EDN07278.1 - 1.8e-05 24.1 0.2 5.3e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 EDN07278.1 - 0.00016 20.5 0.0 0.039 12.6 0.0 2.9 3 0 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EDN07278.1 - 0.0067 15.8 0.0 0.17 11.2 0.0 2.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CoA_binding_2 PF13380.1 EDN07278.1 - 0.11 12.7 0.3 38 4.4 0.0 3.1 2 1 1 3 3 3 0 CoA binding domain Glyco_hydro_63 PF03200.11 EDN07279.1 - 2e-06 25.9 7.4 4.1e-06 24.9 1.1 3.8 3 1 0 3 3 3 1 Mannosyl oligosaccharide glucosidase Neugrin PF06413.6 EDN07280.1 - 1.4e-10 41.3 0.8 3.5e-10 40.1 0.1 1.8 1 1 1 2 2 2 1 Neugrin MRP-L20 PF12824.2 EDN07280.1 - 1.5e-07 31.5 2.4 3e-07 30.5 1.7 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_29 PF13551.1 EDN07280.1 - 0.0002 21.4 0.5 0.00056 20.0 0.4 1.8 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EDN07280.1 - 0.084 12.5 0.0 0.35 10.5 0.0 2.1 1 1 0 1 1 1 0 Homeodomain-like domain Sigma70_r4 PF04545.11 EDN07280.1 - 0.18 11.1 2.1 3.2 7.1 0.0 3.0 3 0 0 3 3 3 0 Sigma-70, region 4 Rgp1 PF08737.5 EDN07281.1 - 2.1e-115 386.1 0.0 3.7e-115 385.3 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 EDN07281.1 - 0.0082 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.6 EDN07281.1 - 0.023 14.0 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 SpoOM protein Mob1_phocein PF03637.12 EDN07283.1 - 8.2e-73 243.7 0.0 1e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 EDN07284.1 - 3.9e-39 134.2 1.1 4.9e-39 133.9 0.8 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit WD40 PF00400.27 EDN07285.1 - 3.1e-17 61.7 6.5 5.7e-05 22.8 0.0 7.2 6 0 0 6 6 6 4 WD domain, G-beta repeat DDE_Tnp_1_7 PF13843.1 EDN07287.1 - 7.6e-32 110.7 1.9 3.3e-20 72.4 0.1 3.1 1 1 2 3 3 3 3 Transposase IS4 RD3 PF14473.1 EDN07287.1 - 0.059 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 RD3 protein Mur_ligase_C PF02875.16 EDN07287.1 - 0.069 13.1 0.1 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain SPO22 PF08631.5 EDN07288.1 - 1.9e-60 204.2 4.1 2.3e-35 122.0 0.0 3.1 2 1 1 3 3 3 2 Meiosis protein SPO22/ZIP4 like SnoaL_2 PF12680.2 EDN07289.1 - 0.095 13.1 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain CENP-Q PF13094.1 EDN07290.1 - 3.5e-48 163.6 3.6 5e-48 163.1 2.5 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF904 PF06005.7 EDN07290.1 - 0.034 14.4 7.1 0.034 14.4 4.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF4444 PF14563.1 EDN07290.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) Spc24 PF08286.6 EDN07290.1 - 0.46 10.1 5.4 0.45 10.2 2.0 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Atg14 PF10186.4 EDN07290.1 - 1.6 7.5 8.8 3.5 6.4 4.9 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 HLH PF00010.21 EDN07291.1 - 1.7e-07 30.7 0.0 3.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain WT1 PF02165.10 EDN07293.1 - 0.069 12.2 0.0 0.091 11.8 0.0 1.1 1 0 0 1 1 1 0 Wilm's tumour protein Rep_fac_C PF08542.6 EDN07294.1 - 4.3e-24 84.2 0.0 1.6e-23 82.5 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EDN07294.1 - 1.3e-11 44.4 0.1 2.6e-11 43.4 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EDN07294.1 - 7.4e-06 26.1 0.1 1.5e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN07294.1 - 0.00026 21.1 1.6 0.0014 18.7 0.6 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EDN07294.1 - 0.0013 18.7 2.2 0.074 13.0 0.7 2.9 2 2 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EDN07294.1 - 0.01 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EDN07294.1 - 0.011 15.7 0.4 0.23 11.5 0.3 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 EDN07294.1 - 0.017 14.6 0.0 0.49 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain T4SS-DNA_transf PF02534.9 EDN07294.1 - 0.088 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer SNF2_N PF00176.18 EDN07294.1 - 0.11 11.3 0.1 0.13 11.0 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ribosomal_L16 PF00252.13 EDN07295.1 - 1.5e-30 105.6 0.8 1.9e-30 105.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Pkinase PF00069.20 EDN07296.1 - 1.1e-19 70.6 0.1 2e-19 69.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07296.1 - 3.1e-10 39.5 0.0 4.1e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN07296.1 - 0.052 12.5 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like F-box-like PF12937.2 EDN07297.1 - 7.6e-07 28.7 0.1 1.3e-05 24.8 0.2 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EDN07297.1 - 0.004 16.7 1.9 0.004 16.7 1.3 4.1 4 1 0 4 4 4 1 F-box domain F-box-like_2 PF13013.1 EDN07297.1 - 0.012 15.2 1.8 0.074 12.7 0.1 2.6 2 1 0 2 2 2 0 F-box-like domain APH PF01636.18 EDN07298.1 - 2.8e-09 37.0 0.0 1.5e-08 34.6 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family RFC1 PF08519.7 EDN07299.1 - 3.5e-60 202.2 0.4 1e-59 200.7 0.1 2.0 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EDN07299.1 - 2.3e-12 46.8 0.0 5.5e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EDN07299.1 - 1.2e-09 38.4 0.2 1e-08 35.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN07299.1 - 2.2e-05 24.6 0.0 5.8e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EDN07299.1 - 2.7e-05 23.0 0.0 0.0005 18.8 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EDN07299.1 - 7.4e-05 23.5 0.0 0.00026 21.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN07299.1 - 0.0028 17.3 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EDN07299.1 - 0.0029 17.4 0.0 0.008 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN07299.1 - 0.0033 17.4 0.0 0.036 14.0 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EDN07299.1 - 0.0047 15.9 0.0 0.015 14.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EDN07299.1 - 0.0083 16.4 0.1 0.032 14.5 0.1 2.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDN07299.1 - 0.028 14.3 0.0 0.079 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EDN07299.1 - 0.041 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDN07299.1 - 0.062 13.0 0.1 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EDN07299.1 - 0.089 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PsbW PF07123.7 EDN07299.1 - 1.8 8.6 3.6 1.2 9.1 0.2 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) NAD_binding_8 PF13450.1 EDN07300.1 - 2e-15 56.5 0.0 4.1e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EDN07300.1 - 3.1e-05 23.2 0.0 0.001 18.2 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EDN07300.1 - 0.0013 18.6 0.0 0.043 13.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDN07300.1 - 0.0034 16.3 0.0 0.0084 15.0 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EDN07300.1 - 0.028 13.4 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EDN07300.1 - 0.08 13.3 0.0 3.2 8.2 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mito_carr PF00153.22 EDN07303.1 - 4.3e-60 199.4 4.6 5.3e-21 74.1 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein UPF0121 PF03661.8 EDN07304.1 - 2.1e-10 40.2 3.4 3e-10 39.6 2.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Septin PF00735.13 EDN07305.1 - 6.8e-124 412.4 0.2 6.8e-124 412.4 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EDN07305.1 - 2e-07 30.9 0.0 4.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EDN07305.1 - 5.4e-05 22.4 0.4 0.00064 18.9 0.3 2.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EDN07305.1 - 0.00013 21.5 1.5 0.0065 15.9 0.0 3.2 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EDN07305.1 - 0.00016 21.9 4.4 0.017 15.4 0.0 2.9 2 1 0 3 3 3 1 ABC transporter AAA_16 PF13191.1 EDN07305.1 - 0.0007 19.6 0.2 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EDN07305.1 - 0.00071 19.0 1.4 0.0013 18.1 0.9 1.9 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EDN07305.1 - 0.0022 18.1 0.3 0.018 15.1 0.0 2.5 2 2 0 2 2 2 1 AAA domain Ras PF00071.17 EDN07305.1 - 0.0023 17.3 0.0 0.011 15.1 0.0 2.2 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EDN07305.1 - 0.0026 18.2 0.8 0.011 16.2 0.0 2.4 3 0 0 3 3 3 1 Miro-like protein AIG1 PF04548.11 EDN07305.1 - 0.0034 16.5 0.0 0.0034 16.5 0.0 2.3 2 1 0 2 2 2 1 AIG1 family ATP_bind_1 PF03029.12 EDN07305.1 - 0.0049 16.4 0.1 1.1 8.7 0.0 3.0 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 EDN07305.1 - 0.0063 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EDN07305.1 - 0.0074 15.7 1.5 0.02 14.4 0.0 2.3 3 0 0 3 3 3 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 EDN07305.1 - 0.011 15.5 7.6 0.46 10.2 0.0 3.7 4 1 0 4 4 4 0 Dynamin family MobB PF03205.9 EDN07305.1 - 0.052 13.2 0.1 0.19 11.4 0.0 2.0 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EDN07305.1 - 0.058 13.5 0.8 0.44 10.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 EDN07305.1 - 0.07 12.7 0.5 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2937 PF11157.3 EDN07305.1 - 0.18 11.1 2.4 0.33 10.2 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) YlqD PF11068.3 EDN07305.1 - 0.27 11.2 11.1 0.67 9.9 7.7 1.7 1 0 0 1 1 1 0 YlqD protein Exonuc_VII_L PF02601.10 EDN07305.1 - 1.1 8.3 12.2 0.96 8.5 7.5 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.6 EDN07305.1 - 1.7 7.8 8.0 2.6 7.2 5.6 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF87 PF01935.12 EDN07305.1 - 3.6 7.3 7.1 2.5 7.8 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 TPK_catalytic PF04263.11 EDN07306.1 - 7.7e-18 64.2 0.0 6.3e-17 61.2 0.0 2.0 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EDN07306.1 - 8.1e-18 63.9 0.0 1.7e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Upf2 PF04050.9 EDN07307.1 - 2.3e-64 216.2 18.6 2.3e-64 216.2 12.9 2.2 2 0 0 2 2 2 1 Up-frameshift suppressor 2 MIF4G PF02854.14 EDN07307.1 - 7.1e-56 188.9 0.0 3.5e-27 95.1 0.0 3.8 4 0 0 4 4 4 2 MIF4G domain SDP_N PF12278.3 EDN07307.1 - 1.2 8.8 15.6 0.015 14.9 1.1 3.1 3 0 0 3 3 3 0 Sex determination protein N terminal p450 PF00067.17 EDN07308.1 - 6.9e-46 156.7 0.1 9.7e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.1 EDN07309.1 - 5.5e-14 52.7 0.0 2.3e-13 50.6 0.0 1.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EDN07309.1 - 1.1e-08 33.8 1.2 0.00029 19.1 0.3 2.9 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EDN07309.1 - 1.8e-08 34.2 0.0 4.7e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EDN07309.1 - 3.3e-05 23.7 0.0 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EDN07309.1 - 7.4e-05 21.8 0.0 0.0055 15.6 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EDN07309.1 - 0.00014 21.0 0.5 0.00037 19.6 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EDN07309.1 - 0.006 15.4 0.2 0.011 14.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EDN07309.1 - 0.0091 15.8 0.0 0.56 10.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EDN07309.1 - 0.042 13.9 0.3 0.32 11.0 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EDN07309.1 - 0.067 12.2 0.4 0.11 11.5 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EDN07309.1 - 0.14 11.1 0.1 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Glyco_transf_8 PF01501.15 EDN07311.1 - 1.8e-25 89.7 0.0 2.1e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 SUN PF03856.8 EDN07312.1 - 1.2e-97 326.0 12.6 1.5e-97 325.7 8.7 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Ribosomal_L1 PF00687.16 EDN07315.1 - 5.4e-58 195.9 2.8 8.1e-58 195.3 2.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family ETF PF01012.16 EDN07316.1 - 2.2e-41 141.3 1.5 2.2e-41 141.3 1.0 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EDN07316.1 - 3.9e-34 116.1 0.0 8.3e-34 115.0 0.0 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain DDE_Tnp_4 PF13359.1 EDN07317.1 - 7.6e-28 97.1 0.0 1.2e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EDN07317.1 - 3.6e-08 33.2 0.0 8.8e-08 31.9 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.1 EDN07317.1 - 0.0034 16.9 0.2 0.0067 15.9 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Plant_tran PF04827.9 EDN07317.1 - 0.0058 16.0 0.0 0.013 14.9 0.0 1.5 1 1 0 1 1 1 1 Plant transposon protein DUF434 PF04256.7 EDN07317.1 - 0.017 14.4 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Hs1pro-1_N PF07231.7 EDN07317.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Hs1pro-1 N-terminus DDE_Tnp_1_2 PF13586.1 EDN07317.1 - 0.023 14.8 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain AAA PF00004.24 EDN07319.1 - 7e-12 45.6 0.0 1.5e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDN07319.1 - 1.9e-06 27.6 0.0 5.8e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN07319.1 - 5.5e-06 26.5 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EDN07319.1 - 2.4e-05 23.2 0.0 4.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EDN07319.1 - 3.2e-05 23.1 0.0 6.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EDN07319.1 - 7.5e-05 22.3 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EDN07319.1 - 0.00027 21.7 0.1 0.00084 20.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EDN07319.1 - 0.00042 20.2 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDN07319.1 - 0.00055 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDN07319.1 - 0.0013 17.9 0.0 0.0026 16.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EDN07319.1 - 0.0019 18.2 0.0 0.011 15.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EDN07319.1 - 0.0035 16.5 0.0 0.0066 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EDN07319.1 - 0.025 14.0 0.0 0.058 12.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.10 EDN07319.1 - 0.03 14.0 0.1 0.09 12.4 0.0 1.8 1 1 0 1 1 1 0 NTPase AAA_18 PF13238.1 EDN07319.1 - 0.032 14.5 0.0 0.089 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EDN07319.1 - 0.08 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EDN07319.1 - 0.13 10.9 0.0 0.51 9.0 0.0 1.9 2 0 0 2 2 2 0 TIP49 C-terminus Arch_ATPase PF01637.13 EDN07319.1 - 0.17 11.5 0.0 1.2 8.7 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 EDN07319.1 - 0.19 10.5 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SWIRM PF04433.12 EDN07320.1 - 1.2e-33 115.0 0.1 2.4e-33 114.1 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EDN07320.1 - 3.7e-07 30.0 0.0 9.8e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN07320.1 - 5.2e-06 26.4 0.0 1.5e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EDN07320.1 - 0.075 12.5 5.6 0.54 9.8 3.9 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type BCMA-Tall_bind PF09257.5 EDN07321.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 BCMA, TALL-1 binding PGAP1 PF07819.8 EDN07322.1 - 1.7e-81 273.1 0.0 3.9e-81 271.9 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein ResIII PF04851.10 EDN07322.1 - 4.6e-20 72.2 0.0 9.2e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDN07322.1 - 4e-14 52.2 0.0 1.1e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN07322.1 - 2.8e-09 36.6 0.0 5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Abhydrolase_5 PF12695.2 EDN07322.1 - 0.00013 21.7 0.0 0.00036 20.2 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN07322.1 - 0.00015 21.7 0.0 0.00048 20.0 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN07322.1 - 0.0019 17.7 0.2 0.0053 16.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.9 EDN07322.1 - 0.013 14.7 0.1 0.026 13.8 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.10 EDN07322.1 - 0.02 13.8 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase COesterase PF00135.23 EDN07322.1 - 0.13 10.9 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family NAD_binding_10 PF13460.1 EDN07323.1 - 2.1e-07 31.1 0.0 5.9e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EDN07323.1 - 0.0043 16.3 0.0 0.0085 15.3 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Cu-oxidase_2 PF07731.9 EDN07325.1 - 1.5e-33 115.1 7.3 1.1e-30 105.9 0.2 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EDN07325.1 - 2e-30 105.7 0.2 2e-30 105.7 0.1 2.7 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EDN07325.1 - 1.4e-27 95.7 8.5 3.9e-27 94.3 3.0 2.9 2 1 0 2 2 2 1 Multicopper oxidase WD40 PF00400.27 EDN07329.1 - 4.2e-54 178.6 20.7 2.3e-10 39.9 0.0 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EDN07329.1 - 1.1e-14 53.9 0.4 2.2e-14 52.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN07329.1 - 4.7e-11 42.0 0.1 1.1e-10 40.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EDN07329.1 - 1.2e-09 36.9 16.7 0.081 11.0 0.2 5.7 2 2 3 5 5 5 5 Nucleoporin Nup120/160 PRANC PF09372.5 EDN07329.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Nucleoporin_N PF08801.6 EDN07329.1 - 0.089 11.5 1.2 3.6 6.2 0.0 2.9 3 0 0 3 3 3 0 Nup133 N terminal like APG17 PF04108.7 EDN07330.1 - 6.2e-125 417.2 0.0 7.3e-125 416.9 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Med4 PF10018.4 EDN07330.1 - 0.012 15.0 1.4 3.9 6.8 0.1 2.8 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4358 PF14270.1 EDN07330.1 - 0.04 13.8 1.3 0.075 12.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Tweety PF04906.8 EDN07330.1 - 0.1 10.9 4.1 0.16 10.3 0.4 2.5 3 0 0 3 3 3 0 Tweety Snapin_Pallidin PF14712.1 EDN07330.1 - 0.13 12.5 4.2 3 8.1 0.0 3.8 5 0 0 5 5 5 0 Snapin/Pallidin DUF4047 PF13256.1 EDN07330.1 - 0.17 11.8 0.9 0.79 9.6 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) IFT20 PF14931.1 EDN07330.1 - 0.25 11.2 9.0 0.92 9.4 0.1 3.8 3 1 0 4 4 4 0 Intraflagellar transport complex B, subunit 20 RIO1 PF01163.17 EDN07331.1 - 1e-73 246.7 0.0 1e-73 246.7 0.0 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EDN07331.1 - 3.5e-05 23.6 0.2 0.0096 15.6 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EDN07331.1 - 0.00069 18.7 0.6 0.011 14.8 0.1 2.5 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SMC_N PF02463.14 EDN07332.1 - 1.9e-49 167.8 62.4 4.1e-48 163.5 43.3 3.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDN07332.1 - 1.7e-31 108.6 1.5 4.1e-30 104.2 0.0 3.3 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EDN07332.1 - 9.4e-18 65.1 3.3 1.4e-09 38.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EDN07332.1 - 6.2e-09 35.3 2.1 6.2e-09 35.3 1.4 3.9 2 2 1 3 3 3 1 AAA ATPase domain Reo_sigmaC PF04582.7 EDN07332.1 - 1.3e-05 24.5 36.5 0.056 12.6 0.7 5.8 4 2 1 5 5 5 4 Reovirus sigma C capsid protein AAA_23 PF13476.1 EDN07332.1 - 2.7e-05 24.6 49.3 2.7e-05 24.6 34.2 6.6 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 EDN07332.1 - 0.00036 20.0 0.0 0.00078 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EDN07332.1 - 0.29 9.5 0.0 0.071 11.5 10.3 6.7 4 2 3 7 7 7 0 AAA domain ABC_tran PF00005.22 EDN07332.1 - 0.47 10.7 0.0 0.47 10.7 0.0 6.1 3 2 1 4 4 4 0 ABC transporter GAS PF13851.1 EDN07332.1 - 5.9 6.0 107.4 0.033 13.3 5.8 6.8 4 2 1 6 6 6 0 Growth-arrest specific micro-tubule binding DUF3605 PF12239.3 EDN07333.1 - 2.8e-47 160.4 3.0 5.9e-44 149.6 2.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) FAD_binding_6 PF00970.19 EDN07334.1 - 5.4e-30 103.4 0.0 8.8e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EDN07334.1 - 1.9e-27 96.0 0.0 3.1e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EDN07334.1 - 9e-06 25.6 0.0 0.00086 19.2 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EDN07334.1 - 0.00042 20.2 0.0 0.0009 19.1 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain tRNA-synt_1d PF00750.14 EDN07335.1 - 2e-80 270.2 8.4 6.1e-41 140.4 4.3 2.0 1 1 1 2 2 2 2 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.11 EDN07335.1 - 0.00079 19.9 0.1 0.0035 17.8 0.0 2.2 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain AAA_3 PF07726.6 EDN07335.1 - 0.028 14.0 0.0 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Med9 PF07544.8 EDN07335.1 - 0.049 13.3 1.4 0.12 12.1 1.0 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Calsarcin PF05556.6 EDN07338.1 - 0.0004 19.6 0.7 0.00064 19.0 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) SelP_N PF04592.9 EDN07338.1 - 1.5 8.1 6.2 2.5 7.4 4.3 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RRM_1 PF00076.17 EDN07339.1 - 0.0064 16.1 0.0 0.032 13.8 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN07339.1 - 0.044 13.6 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pilt PF15453.1 EDN07339.1 - 9.7 5.7 14.1 2.7 7.6 4.2 2.1 2 0 0 2 2 2 0 Protein incorporated later into Tight Junctions Herpes_U34 PF04541.8 EDN07341.1 - 0.052 12.4 0.0 0.066 12.1 0.0 1.2 1 1 0 1 1 1 0 Herpesvirus virion protein U34 DEAD PF00270.24 EDN07343.1 - 1.1e-42 145.4 0.3 2.7e-42 144.1 0.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN07343.1 - 3e-22 78.2 0.1 1.6e-11 43.9 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EDN07343.1 - 0.00044 20.1 0.7 0.00096 19.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PBP1_TM PF14812.1 EDN07343.1 - 2.5 8.4 8.2 8.1 6.8 5.7 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Acyltransferase PF01553.16 EDN07345.1 - 4.8e-05 22.8 0.0 6.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase L31 PF09784.4 EDN07348.1 - 2.2e-47 159.3 1.8 2.4e-47 159.2 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 DUF2161 PF09929.4 EDN07348.1 - 0.065 13.1 0.3 0.093 12.6 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) DUF1639 PF07797.9 EDN07348.1 - 0.068 12.5 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) Annexin PF00191.15 EDN07349.1 - 3.7e-59 196.5 3.4 1.3e-17 63.4 0.0 4.3 4 0 0 4 4 4 4 Annexin Glyco_transf_7C PF02709.9 EDN07349.1 - 0.012 15.0 0.3 0.023 14.1 0.2 1.4 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Acetyltransf_11 PF13720.1 EDN07349.1 - 0.035 14.3 0.7 1.8 8.8 0.0 3.1 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 EBP PF05241.7 EDN07350.1 - 1.2e-69 233.2 5.3 1.4e-69 232.9 3.7 1.1 1 0 0 1 1 1 1 Emopamil binding protein tRNA-synt_1d PF00750.14 EDN07351.1 - 6.6e-57 192.9 0.7 4.1e-49 167.2 0.1 2.4 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EDN07351.1 - 1.7e-18 66.6 0.4 1.4e-17 63.7 0.3 2.4 1 1 0 1 1 1 1 DALR anticodon binding domain Retro_M PF02813.9 EDN07351.1 - 0.041 14.0 0.0 0.23 11.6 0.0 2.2 2 0 0 2 2 2 0 Retroviral M domain SH3_9 PF14604.1 EDN07352.1 - 5.1e-05 22.7 0.2 5.1e-05 22.7 0.1 2.6 3 0 0 3 3 3 1 Variant SH3 domain ZZ PF00569.12 EDN07352.1 - 0.0013 18.2 5.5 0.0013 18.2 3.8 2.4 2 0 0 2 2 2 1 Zinc finger, ZZ type SH3_2 PF07653.12 EDN07352.1 - 0.047 13.1 0.0 0.047 13.1 0.0 2.3 3 0 0 3 3 3 0 Variant SH3 domain Macoilin PF09726.4 EDN07352.1 - 0.79 7.9 6.7 1.3 7.1 4.6 1.3 1 0 0 1 1 1 0 Transmembrane protein CBM_21 PF03370.8 EDN07353.1 - 2.1e-34 117.8 3.0 3.6e-34 117.1 2.1 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Histone PF00125.19 EDN07354.1 - 1.9e-15 56.7 0.3 2.3e-15 56.4 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDN07354.1 - 4.9e-05 23.4 0.1 6.6e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EDN07354.1 - 7.1e-05 22.6 0.2 0.0001 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EDN07354.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EDN07354.1 - 0.0026 17.4 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 EDN07354.1 - 0.011 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 EDN07354.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Mito_carr PF00153.22 EDN07355.1 - 1.9e-45 152.4 1.9 3.3e-15 55.5 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Glutaredoxin PF00462.19 EDN07356.1 - 5e-15 55.2 0.0 3e-14 52.7 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin SIN1 PF05422.7 EDN07357.1 - 6.6e-33 114.0 0.0 9.2e-19 67.3 0.0 2.3 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EDN07357.1 - 0.021 14.7 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Pkinase PF00069.20 EDN07358.1 - 5.4e-65 219.1 0.0 7.4e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07358.1 - 4e-34 117.8 0.0 5.6e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN07358.1 - 4.3e-07 29.1 0.0 6.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EDN07358.1 - 0.023 14.0 0.6 0.084 12.1 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF2615 PF11027.3 EDN07358.1 - 0.13 12.1 0.5 0.42 10.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Rad21_Rec8 PF04824.11 EDN07358.1 - 0.17 11.0 0.2 0.4 9.9 0.1 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein zf-Tim10_DDP PF02953.10 EDN07359.1 - 6.8e-23 79.7 0.4 8.5e-23 79.4 0.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger AflR PF08493.5 EDN07359.1 - 0.0053 15.8 0.4 0.006 15.6 0.2 1.1 1 0 0 1 1 1 1 Aflatoxin regulatory protein Ins_beta PF03488.9 EDN07359.1 - 0.056 13.2 0.3 0.097 12.4 0.2 1.3 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type Lectin_leg-like PF03388.8 EDN07360.1 - 2.3e-64 216.6 0.0 3e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family ATG27 PF09451.5 EDN07360.1 - 0.0056 15.9 0.1 0.0069 15.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Lectin_legB PF00139.14 EDN07360.1 - 0.012 15.0 0.0 0.074 12.4 0.0 2.1 1 1 0 1 1 1 0 Legume lectin domain DDE_1 PF03184.14 EDN07361.1 - 7e-10 38.3 0.0 2.4e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN07361.1 - 0.0034 17.1 0.0 0.015 15.0 0.0 2.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Borrelia_P83 PF05262.6 EDN07361.1 - 0.19 9.9 18.2 0.27 9.4 12.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Asp-B-Hydro_N PF05279.6 EDN07361.1 - 6.4 6.5 16.4 10 5.8 11.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region OmpH PF03938.9 EDN07362.1 - 0.0013 18.7 5.9 0.0026 17.7 4.1 1.6 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) APH PF01636.18 EDN07362.1 - 0.021 14.5 0.4 0.021 14.5 0.3 3.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN07362.1 - 0.022 14.3 0.0 0.054 13.0 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EDN07362.1 - 0.046 13.0 0.1 0.046 13.0 0.0 1.8 2 0 0 2 2 2 0 RIO1 family HAUS6_N PF14661.1 EDN07362.1 - 3.4 6.9 15.2 6.1 6.1 10.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Atg14 PF10186.4 EDN07362.1 - 3.8 6.3 16.1 8.7 5.1 11.2 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Beta-lactamase PF00144.19 EDN07365.1 - 1.5e-24 86.6 0.0 2.9e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase PRCC PF10253.4 EDN07366.1 - 3.5e-42 145.1 1.6 3.5e-42 145.1 1.1 1.9 2 0 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting AAA_5 PF07728.9 EDN07367.1 - 2.6e-128 422.4 0.1 6.9e-22 77.6 0.0 9.7 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 EDN07367.1 - 1.4e-33 115.9 0.7 1.1e-05 25.6 0.1 7.5 7 0 0 7 7 6 6 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 EDN07367.1 - 4.5e-28 97.4 0.0 1.8e-10 40.5 0.0 7.3 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDN07367.1 - 2e-23 83.5 0.0 0.0012 19.6 0.0 7.4 6 0 0 6 6 6 4 AAA domain AAA_16 PF13191.1 EDN07367.1 - 3.1e-22 79.4 11.7 0.00041 20.3 0.0 8.0 7 0 0 7 7 6 5 AAA ATPase domain AAA_22 PF13401.1 EDN07367.1 - 2.9e-21 75.9 0.2 0.011 15.8 0.0 7.8 7 0 0 7 7 6 4 AAA domain AAA_33 PF13671.1 EDN07367.1 - 2e-19 69.8 0.0 0.097 12.5 0.0 7.7 7 0 0 7 7 6 5 AAA domain AAA_14 PF13173.1 EDN07367.1 - 5.4e-19 68.3 0.0 0.0011 18.8 0.0 7.8 8 0 0 8 8 6 3 AAA domain AAA_18 PF13238.1 EDN07367.1 - 6.6e-18 65.2 1.2 0.048 13.9 0.0 7.1 6 0 0 6 6 6 3 AAA domain ABC_tran PF00005.22 EDN07367.1 - 1.5e-16 60.9 4.8 0.0044 17.3 0.0 7.0 6 0 0 6 6 6 3 ABC transporter Sigma54_activ_2 PF14532.1 EDN07367.1 - 1.2e-15 57.7 2.4 0.0038 17.2 0.1 7.3 7 0 0 7 7 7 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 EDN07367.1 - 1.5e-15 57.0 0.0 0.0073 15.8 0.0 6.4 6 0 0 6 6 6 3 Sigma-54 interaction domain UPF0079 PF02367.12 EDN07367.1 - 2.5e-13 49.7 4.8 0.17 11.4 0.0 6.6 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EDN07367.1 - 2.8e-13 49.3 4.3 0.031 14.0 0.1 6.4 6 0 0 6 6 6 3 Part of AAA domain Mg_chelatase PF01078.16 EDN07367.1 - 3.3e-12 46.0 1.5 1.8 7.6 0.0 8.5 9 0 0 9 9 9 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EDN07367.1 - 3.9e-12 46.1 9.4 0.078 12.6 0.0 6.4 6 0 0 6 6 6 3 NACHT domain Miro PF08477.8 EDN07367.1 - 4e-12 46.6 4.6 0.085 13.3 0.0 7.0 6 0 0 6 6 6 2 Miro-like protein Zeta_toxin PF06414.7 EDN07367.1 - 1.2e-11 44.0 3.2 0.39 9.7 0.0 7.9 8 0 0 8 8 7 2 Zeta toxin SRP54 PF00448.17 EDN07367.1 - 1.5e-10 40.8 3.6 0.55 9.6 0.0 5.9 6 0 0 6 6 6 4 SRP54-type protein, GTPase domain T2SE PF00437.15 EDN07367.1 - 1.9e-10 40.0 2.4 0.46 9.3 0.0 6.1 6 0 0 6 6 6 3 Type II/IV secretion system protein RNA_helicase PF00910.17 EDN07367.1 - 4e-09 36.6 6.4 5.2 7.3 0.0 7.6 7 0 0 7 7 7 0 RNA helicase RuvB_N PF05496.7 EDN07367.1 - 6.2e-09 35.2 3.1 0.74 8.8 0.0 6.4 6 0 0 6 6 6 2 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EDN07367.1 - 7.4e-09 35.0 6.6 1.1 8.8 0.0 6.6 6 0 0 6 6 6 1 P-loop containing region of AAA domain DUF258 PF03193.11 EDN07367.1 - 1.5e-08 34.0 6.6 0.18 10.9 0.1 6.0 7 0 0 7 7 5 2 Protein of unknown function, DUF258 MobB PF03205.9 EDN07367.1 - 1.8e-08 34.1 4.8 1.2 8.8 0.0 6.5 6 0 0 6 6 6 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EDN07367.1 - 4.7e-08 32.6 3.8 0.26 10.6 0.0 6.1 6 0 0 6 6 5 1 AAA domain PduV-EutP PF10662.4 EDN07367.1 - 4.8e-08 32.5 6.0 0.27 10.7 0.0 6.3 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.2 EDN07367.1 - 1.6e-07 30.6 1.0 2 7.4 0.0 5.3 6 0 0 6 6 5 1 P-loop containing dynein motor region D3 AAA_28 PF13521.1 EDN07367.1 - 1.8e-06 28.0 12.6 0.17 11.8 0.4 6.2 6 0 0 6 6 6 2 AAA domain Bac_DnaA PF00308.13 EDN07367.1 - 2.3e-06 27.4 0.4 2.4 7.7 0.0 4.8 4 0 0 4 4 4 1 Bacterial dnaA protein IstB_IS21 PF01695.12 EDN07367.1 - 4.9e-06 26.0 0.6 1.9 7.8 0.0 5.3 6 0 0 6 6 5 1 IstB-like ATP binding protein ResIII PF04851.10 EDN07367.1 - 2.4e-05 24.2 1.2 1.6 8.5 0.0 4.8 5 0 0 5 5 3 2 Type III restriction enzyme, res subunit PhoH PF02562.11 EDN07367.1 - 0.00012 21.4 0.7 6.2 5.9 0.0 5.2 6 0 0 6 6 5 0 PhoH-like protein ATP_bind_1 PF03029.12 EDN07367.1 - 0.00029 20.4 7.7 11 5.4 0.1 6.4 7 0 0 7 7 6 0 Conserved hypothetical ATP binding protein CPT PF07931.7 EDN07367.1 - 0.00039 20.0 2.8 0.86 9.2 0.0 5.4 6 1 0 6 6 4 1 Chloramphenicol phosphotransferase-like protein MMR_HSR1 PF01926.18 EDN07367.1 - 0.00054 19.8 1.6 55 3.7 0.0 5.9 6 0 0 6 6 6 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 EDN07367.1 - 0.00058 19.4 3.6 1.4 8.3 0.2 5.2 5 1 0 5 5 5 1 Viral (Superfamily 1) RNA helicase TIP49 PF06068.8 EDN07367.1 - 0.0011 17.8 2.2 2.6 6.6 0.0 4.8 5 0 0 5 5 5 1 TIP49 C-terminus cobW PF02492.14 EDN07367.1 - 0.0032 16.9 8.8 8.6 5.7 0.0 5.2 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EDN07367.1 - 0.0042 16.8 9.4 1.4 8.5 0.0 5.4 5 0 0 5 5 5 1 NTPase ATP-synt_ab PF00006.20 EDN07367.1 - 0.0046 16.4 0.2 10 5.5 0.0 3.9 4 0 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain CbiA PF01656.18 EDN07367.1 - 0.0063 15.9 0.6 0.46 9.8 0.0 3.2 3 0 0 3 3 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain KaiC PF06745.8 EDN07367.1 - 0.014 14.4 3.2 14 4.7 0.0 5.3 7 0 0 7 7 5 0 KaiC MCM PF00493.18 EDN07367.1 - 0.029 13.1 1.3 6.9 5.3 0.0 4.3 5 0 0 5 5 5 0 MCM2/3/5 family PRK PF00485.13 EDN07367.1 - 0.031 13.8 0.3 7.1 6.1 0.0 3.9 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family Voltage_CLC PF00654.15 EDN07368.1 - 1.5e-75 254.4 25.4 1.5e-75 254.4 17.6 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EDN07368.1 - 7.8e-07 28.7 0.1 0.002 17.8 0.0 2.8 3 0 0 3 3 3 2 CBS domain P5CR_dimer PF14748.1 EDN07369.1 - 6e-33 113.0 2.5 1.1e-32 112.2 1.7 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EDN07369.1 - 1.7e-10 41.1 0.0 4.8e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pex26 PF07163.7 EDN07369.1 - 0.039 12.8 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Pex26 protein CTK3 PF12243.3 EDN07370.1 - 1.6e-58 196.2 0.5 2.2e-58 195.7 0.3 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EDN07370.1 - 2.1e-22 78.9 9.3 2.1e-22 78.9 6.4 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus NAM-associated PF14303.1 EDN07370.1 - 0.53 10.6 5.7 0.22 11.8 0.3 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Rhabdo_ncap PF00945.13 EDN07371.1 - 0.6 8.6 3.0 0.9 8.0 2.1 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF155 PF02582.9 EDN07372.1 - 2.1e-52 177.5 0.1 4.5e-52 176.4 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF3253 PF11625.3 EDN07373.1 - 0.099 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) DUF2018 PF09442.5 EDN07373.1 - 0.22 12.1 0.4 2.4 8.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2018) WD40 PF00400.27 EDN07374.1 - 1.1e-36 123.4 14.3 5.4e-08 32.4 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat F-box-like PF12937.2 EDN07374.1 - 9.9e-11 41.2 0.4 1.9e-10 40.3 0.3 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EDN07374.1 - 1.1e-06 27.0 9.3 0.13 10.3 0.1 4.7 1 1 3 4 4 4 4 Nucleoporin Nup120/160 F-box PF00646.28 EDN07374.1 - 0.00019 20.9 0.6 0.00039 19.9 0.4 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EDN07374.1 - 0.026 13.9 1.5 1 8.7 0.1 2.7 1 1 0 2 2 2 0 PQQ-like domain Zip PF02535.17 EDN07375.1 - 2.6e-32 112.0 6.5 1.6e-28 99.6 3.5 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter Hat1_N PF10394.4 EDN07376.1 - 1.5e-46 158.4 0.1 2.3e-46 157.7 0.1 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus LSM PF01423.17 EDN07378.1 - 2.3e-17 62.2 0.0 3.6e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDN07378.1 - 0.016 15.1 0.0 0.029 14.2 0.0 1.5 1 1 1 2 2 2 0 Ataxin 2 SM domain API5 PF05918.6 EDN07378.1 - 7.3 4.9 10.6 8.3 4.7 7.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DSPc PF00782.15 EDN07379.1 - 1.9e-10 40.4 0.0 3.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDN07379.1 - 0.0017 17.7 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EDN07379.1 - 0.016 15.4 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EDN07379.1 - 0.089 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate PPR_2 PF13041.1 EDN07380.1 - 3.7e-20 71.6 0.2 0.00076 19.4 0.0 7.1 6 1 1 7 7 7 4 PPR repeat family PPR_3 PF13812.1 EDN07380.1 - 1e-13 50.3 4.3 0.024 14.9 0.0 8.1 7 1 1 8 8 8 2 Pentatricopeptide repeat domain PPR PF01535.15 EDN07380.1 - 1.1e-11 43.8 9.3 0.067 13.1 0.1 7.7 8 1 0 8 8 8 3 PPR repeat PPR_1 PF12854.2 EDN07380.1 - 0.021 14.2 1.3 23 4.5 0.0 4.9 6 1 0 6 6 6 0 PPR repeat PLA2_B PF01735.13 EDN07381.1 - 9.3e-25 86.7 0.0 4.1e-24 84.6 0.0 1.9 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Exo70 PF03081.10 EDN07382.1 - 2.9e-70 236.9 0.0 1.7e-69 234.3 0.0 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit TPD52 PF04201.10 EDN07382.1 - 0.033 13.9 0.1 0.1 12.3 0.1 1.8 1 0 0 1 1 1 0 Tumour protein D52 family Sec3_C PF09763.4 EDN07382.1 - 0.12 10.4 0.9 0.24 9.4 0.6 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec3 Podoplanin PF05808.6 EDN07383.1 - 0.00055 19.5 0.8 0.00088 18.8 0.6 1.2 1 0 0 1 1 1 1 Podoplanin DUF2668 PF10873.3 EDN07383.1 - 0.0021 18.2 4.8 0.0021 18.2 3.3 3.1 3 1 0 3 3 3 2 Protein of unknown function (DUF2668) BCDHK_Adom3 PF10436.4 EDN07384.1 - 1.2e-68 229.7 0.0 1.9e-68 229.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EDN07384.1 - 1.8e-17 63.0 0.0 6.8e-17 61.1 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EDN07384.1 - 0.0091 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MFS_1 PF07690.11 EDN07385.1 - 1.7e-23 82.8 39.9 1.7e-23 82.8 27.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Methyltransf_2 PF00891.13 EDN07386.1 - 3.6e-31 108.2 0.0 5.6e-31 107.5 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase SKN1 PF03935.10 EDN07388.1 - 2.6e-206 685.6 0.0 3.3e-206 685.2 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Fructosamin_kin PF03881.9 EDN07391.1 - 2.8e-58 197.1 0.0 3.5e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EDN07391.1 - 5.7e-06 26.2 0.0 7.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_L3 PF00297.17 EDN07392.1 - 3e-118 393.9 8.6 3.5e-118 393.7 6.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 YqgF PF14639.1 EDN07393.1 - 0.083 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 DUF3435 PF11917.3 EDN07394.1 - 1.5e-168 560.8 0.1 3e-168 559.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) USP7_C2 PF14533.1 EDN07394.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal YebF PF13995.1 EDN07395.1 - 0.029 14.3 0.0 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 YebF-like protein DEAD PF00270.24 EDN07396.1 - 2.8e-11 43.2 0.0 6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN07396.1 - 4.8e-05 23.2 0.0 0.00067 19.5 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDN07396.1 - 0.11 12.6 0.1 0.39 10.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.20 EDN07397.1 - 1.1e-08 34.5 0.0 2.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN07397.1 - 0.0016 18.2 0.1 0.022 14.4 0.1 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN07397.1 - 0.016 14.2 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase F-box-like PF12937.2 EDN07398.1 - 0.00093 18.8 0.9 0.0016 18.1 0.6 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN07398.1 - 0.064 12.9 0.7 0.1 12.2 0.5 1.3 1 0 0 1 1 1 0 F-box domain TPR_1 PF00515.23 EDN07400.1 - 4.3e-51 168.5 23.7 4.8e-08 32.2 0.0 11.0 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 EDN07400.1 - 4.1e-46 151.2 18.4 2.3e-06 27.0 0.0 10.7 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 EDN07400.1 - 4e-43 144.9 19.7 3.2e-11 42.6 0.6 6.3 2 2 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 EDN07400.1 - 1.2e-38 127.9 17.0 3.6e-06 26.3 0.0 10.3 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 EDN07400.1 - 9.2e-34 115.3 5.6 1.4e-07 31.9 0.0 6.6 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EDN07400.1 - 4.8e-29 100.1 21.9 4.6e-08 32.8 0.3 7.0 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 EDN07400.1 - 2.8e-27 92.6 16.1 0.00053 19.9 0.1 10.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 EDN07400.1 - 4.1e-26 89.0 7.3 7.1e-05 23.1 0.0 9.1 4 3 5 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.1 EDN07400.1 - 1.4e-22 77.6 12.1 0.0033 17.1 0.0 9.9 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EDN07400.1 - 2.4e-21 75.8 13.8 3.8e-05 23.9 0.0 6.5 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 EDN07400.1 - 2.9e-21 74.4 13.7 0.00055 20.2 0.0 10.0 10 0 0 10 10 10 4 Tetratricopeptide repeat Apc3 PF12895.2 EDN07400.1 - 1e-12 48.0 11.8 3.9e-08 33.3 2.0 4.2 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EDN07400.1 - 2.8e-12 46.3 9.1 0.0038 17.0 0.1 6.5 2 1 3 7 7 7 4 Tetratricopeptide repeat TPR_15 PF13429.1 EDN07400.1 - 6.3e-09 35.3 9.9 0.00032 19.8 2.0 5.0 1 1 3 4 4 4 3 Tetratricopeptide repeat DUF1777 PF08648.7 EDN07400.1 - 0.0047 16.6 7.7 0.0047 16.6 5.3 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1777) TPR_20 PF14561.1 EDN07400.1 - 0.0054 16.8 1.7 0.79 9.8 0.0 4.1 3 1 1 4 4 3 1 Tetratricopeptide repeat DUF2225 PF09986.4 EDN07400.1 - 0.013 15.0 4.3 0.42 10.0 0.0 3.3 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 EDN07400.1 - 0.14 12.1 11.4 21 5.2 0.1 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 EDN07400.1 - 0.35 10.7 0.0 0.11 12.3 2.7 5.4 4 2 2 6 6 4 0 Tetratricopeptide repeat MIT PF04212.13 EDN07400.1 - 0.7 9.8 21.9 0.77 9.6 1.4 6.0 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 EDN07400.1 - 2.9 6.5 4.4 4.8 5.8 0.1 2.9 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) NUC173 PF08161.7 EDN07402.1 - 3.5e-80 268.0 0.3 1.7e-79 265.7 0.1 2.3 3 0 0 3 3 3 1 NUC173 domain HEAT_2 PF13646.1 EDN07402.1 - 0.22 11.8 5.2 4.3 7.6 0.1 5.0 4 2 2 6 6 6 0 HEAT repeats Cortex-I_coil PF09304.5 EDN07402.1 - 0.41 10.6 2.8 3.3 7.7 0.1 2.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil LSM PF01423.17 EDN07403.1 - 0.062 12.8 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 LSM domain PAT1 PF09770.4 EDN07403.1 - 0.16 10.1 7.1 0.18 10.0 4.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EDN07403.1 - 6.9 5.9 14.6 11 5.2 10.2 1.3 1 0 0 1 1 1 0 Vta1 like zf-C2H2 PF00096.21 EDN07404.1 - 8.3 6.9 6.7 3.3 8.2 1.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN07404.1 - 8.4 6.9 11.4 0.49 10.8 1.5 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger ArsB PF02040.10 EDN07406.1 - 1.3e-12 47.4 21.0 3.4e-07 29.5 6.0 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein RXT2_N PF08595.6 EDN07406.1 - 2.6 7.8 4.7 5.5 6.7 0.5 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal Ribonuclease_3 PF00636.21 EDN07407.1 - 4.4e-41 139.9 0.4 4.5e-19 68.9 0.0 3.4 3 0 0 3 3 3 2 Ribonuclease III domain Dicer_dimer PF03368.9 EDN07407.1 - 1.3e-24 85.8 0.0 3e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.1 EDN07407.1 - 3.6e-22 78.6 0.3 3.2e-11 43.2 0.0 3.7 2 1 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.24 EDN07407.1 - 1.1e-16 60.7 0.0 2.6e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN07407.1 - 2.1e-13 49.9 0.3 1.1e-12 47.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN07407.1 - 1.2e-07 31.7 0.0 4.9e-07 29.7 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Proteasome PF00227.21 EDN07408.1 - 1.9e-56 190.3 0.0 2.5e-32 111.6 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EDN07408.1 - 1.8e-11 43.1 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.10 EDN07408.1 - 0.048 12.1 0.1 0.69 8.3 0.0 2.0 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Methyltransf_2 PF00891.13 EDN07408.1 - 0.17 11.0 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase RINGv PF12906.2 EDN07409.1 - 6.2e-09 35.7 1.5 6.2e-09 35.7 1.0 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EDN07409.1 - 0.02 14.7 1.1 0.02 14.7 0.8 2.1 2 0 0 2 2 2 0 Ring finger domain zf-RanBP PF00641.13 EDN07409.1 - 0.039 13.0 0.1 0.092 11.8 0.0 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Cytochrom_B_N PF00033.14 EDN07409.1 - 0.11 11.9 2.8 0.16 11.2 1.9 1.3 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB PHD PF00628.24 EDN07409.1 - 4.7 6.9 6.6 1.4 8.6 2.0 1.9 2 0 0 2 2 2 0 PHD-finger Aldo_ket_red PF00248.16 EDN07410.1 - 1.7e-40 138.6 0.0 2.1e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 EDN07411.1 - 2.4e-12 46.3 2.0 1e-11 44.2 1.4 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN07411.1 - 5.8e-05 22.9 10.1 9.8e-05 22.1 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EDN07412.1 - 4.3e-34 117.7 68.7 1.5e-29 102.8 31.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EDN07412.1 - 2.8e-06 27.0 0.5 0.014 15.1 0.1 3.0 2 0 0 2 2 2 2 MFS_1 like family Zn_clus PF00172.13 EDN07413.1 - 1.1e-07 31.6 10.0 2.4e-07 30.5 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDN07413.1 - 0.0015 17.4 0.3 0.0031 16.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EDN07414.1 - 9.9e-88 294.6 31.4 1.2e-87 294.4 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN07414.1 - 4.6e-11 42.0 35.9 4.6e-11 42.0 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RVT_2 PF07727.9 EDN07415.1 - 3.6e-05 22.8 0.0 5.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) APH PF01636.18 EDN07416.1 - 1.1e-08 35.1 0.1 6.1e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family KNOX2 PF03791.8 EDN07416.1 - 0.005 16.0 0.4 0.012 14.8 0.3 1.6 1 0 0 1 1 1 1 KNOX2 domain Kdo PF06293.9 EDN07417.1 - 0.00015 20.9 0.0 0.0002 20.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EDN07417.1 - 0.00092 18.4 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EDN07417.1 - 0.056 13.0 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EDN07419.1 - 3.5e-09 36.7 0.0 4.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3829 PF12889.2 EDN07421.1 - 0.011 14.9 0.2 0.015 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) UPF0184 PF03670.8 EDN07421.1 - 0.013 15.6 6.3 0.24 11.5 1.5 2.7 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) Snapin_Pallidin PF14712.1 EDN07421.1 - 0.033 14.4 0.7 0.085 13.1 0.5 1.8 1 0 0 1 1 1 0 Snapin/Pallidin Seryl_tRNA_N PF02403.17 EDN07421.1 - 0.038 14.0 0.9 0.52 10.3 0.0 2.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain AKNA PF12443.3 EDN07421.1 - 0.04 13.9 0.3 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 AT-hook-containing transcription factor Baculo_PEP_C PF04513.7 EDN07421.1 - 0.045 13.5 6.5 0.038 13.8 3.4 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.3 EDN07421.1 - 0.046 13.6 0.8 0.064 13.1 0.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.4 EDN07421.1 - 0.05 13.7 0.4 0.14 12.3 0.1 2.0 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.7 EDN07421.1 - 0.051 13.3 1.1 0.23 11.2 0.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DASH_Spc19 PF08287.6 EDN07421.1 - 0.057 13.0 0.5 0.077 12.5 0.4 1.3 1 0 0 1 1 1 0 Spc19 Tropomyosin_1 PF12718.2 EDN07421.1 - 0.063 13.1 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Tropomyosin like NTR2 PF15458.1 EDN07421.1 - 0.07 12.3 0.5 0.09 11.9 0.4 1.1 1 0 0 1 1 1 0 Nineteen complex-related protein 2 TBPIP PF07106.8 EDN07421.1 - 0.087 12.3 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mer2 PF09074.5 EDN07421.1 - 0.088 12.7 1.7 0.2 11.5 0.1 2.0 1 1 1 2 2 2 0 Mer2 KLRAQ PF10205.4 EDN07421.1 - 0.088 12.8 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein CDC37_N PF03234.9 EDN07421.1 - 0.094 13.0 0.1 0.13 12.5 0.1 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Viral_P18 PF04521.8 EDN07421.1 - 0.11 11.9 0.2 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein NPV_P10 PF05531.7 EDN07421.1 - 0.14 12.4 3.1 1 9.6 2.0 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MerR-DNA-bind PF09278.6 EDN07421.1 - 0.28 11.6 3.2 0.88 10.0 1.7 2.1 1 1 1 2 2 2 0 MerR, DNA binding DUF2730 PF10805.3 EDN07421.1 - 0.28 10.9 1.5 0.52 10.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF4164 PF13747.1 EDN07421.1 - 0.3 11.2 4.6 0.81 9.8 3.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DASH_Dam1 PF08653.5 EDN07421.1 - 9.5 6.0 7.1 3.9 7.3 1.0 3.0 3 1 1 4 4 4 0 DASH complex subunit Dam1 Vps39_1 PF10366.4 EDN07422.1 - 2.5e-30 104.6 0.0 4.9e-29 100.5 0.0 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 EDN07422.1 - 9.1e-23 81.0 0.0 2.5e-22 79.6 0.0 1.7 1 1 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 EDN07422.1 - 7.4e-14 51.8 0.0 2.1e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 EDN07422.1 - 2.9e-07 30.1 0.0 7.2e-06 25.6 0.0 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS DUF3504 PF12012.3 EDN07422.1 - 0.072 12.8 0.1 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) 6PF2K PF01591.13 EDN07423.1 - 1.6e-69 233.3 0.0 2.2e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EDN07423.1 - 2e-35 122.2 0.0 4e-35 121.2 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EDN07423.1 - 5.3e-07 29.6 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EDN07423.1 - 0.0012 18.1 0.0 0.0032 16.7 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 DUF4398 PF14346.1 EDN07424.1 - 0.16 12.0 1.4 0.25 11.4 0.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) RVT_1 PF00078.22 EDN07425.1 - 2.9e-19 69.2 0.0 6.3e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FlxA PF14282.1 EDN07425.1 - 1.5 8.7 10.2 1.1 9.2 2.4 2.2 2 0 0 2 2 2 0 FlxA-like protein SlyX PF04102.7 EDN07425.1 - 4.8 7.6 10.0 3.6 8.0 1.3 3.0 3 0 0 3 3 3 0 SlyX SUR7 PF06687.7 EDN07426.1 - 0.15 11.5 6.1 0.19 11.2 4.2 1.1 1 0 0 1 1 1 0 SUR7/PalI family zf-CCHC PF00098.18 EDN07427.1 - 0.015 15.2 5.6 0.024 14.5 3.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Cytochrom_C550 PF14495.1 EDN07427.1 - 0.043 13.2 0.5 0.11 11.9 0.4 1.7 1 0 0 1 1 1 0 Cytochrome c-550 domain zf-CCHC_2 PF13696.1 EDN07427.1 - 4.4 6.8 7.3 0.27 10.7 1.0 2.0 2 0 0 2 2 2 0 Zinc knuckle RVT_1 PF00078.22 EDN07428.1 - 3e-24 85.5 0.0 7.6e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN07428.1 - 5e-16 58.8 0.1 3.1e-15 56.3 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.5 EDN07428.1 - 0.0039 16.5 0.1 0.012 15.0 0.0 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger FAD_binding_4 PF01565.18 EDN07430.1 - 2.2e-24 85.4 2.0 3.4e-24 84.8 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain DUF3435 PF11917.3 EDN07431.1 - 9.5e-140 465.9 4.5 6.6e-125 417.0 0.3 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EDN07431.1 - 4.5e-05 23.1 0.0 0.00062 19.4 0.0 2.3 2 0 0 2 2 2 1 Phage integrase family OmpH PF03938.9 EDN07431.1 - 0.22 11.4 8.4 0.4 10.5 0.0 2.7 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) HbrB PF08539.6 EDN07432.1 - 2.9e-52 176.6 0.0 4.3e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 HbrB-like Myb_DNA-bind_6 PF13921.1 EDN07433.1 - 2.2e-07 30.8 0.9 2.4e-06 27.5 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDN07433.1 - 0.03 14.4 1.9 0.039 14.0 0.1 2.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EDN07433.1 - 0.046 14.3 0.1 1.4 9.5 0.0 2.3 1 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain AAA PF00004.24 EDN07434.1 - 3.1e-16 59.7 0.0 8.9e-16 58.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EDN07434.1 - 1.9e-05 24.3 0.4 7.1e-05 22.4 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EDN07434.1 - 0.00018 21.6 0.5 0.0044 17.1 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 EDN07434.1 - 0.00018 21.2 0.0 0.00058 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDN07434.1 - 0.0045 16.9 0.0 0.017 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain MIP-T3 PF10243.4 EDN07434.1 - 0.0089 14.5 56.7 0.014 13.9 39.3 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 AAA_17 PF13207.1 EDN07434.1 - 0.014 16.2 0.1 0.09 13.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EDN07434.1 - 0.025 14.4 2.0 0.042 13.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain CDK2AP PF09806.4 EDN07435.1 - 0.88 9.7 6.8 1.1 9.5 4.7 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2051 PF09738.4 EDN07435.1 - 2.3 7.4 9.4 3 7.0 6.5 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Chorion_2 PF03964.10 EDN07435.1 - 4.7 7.8 9.4 5.6 7.5 6.5 1.3 1 1 0 1 1 1 0 Chorion family 2 DUF1675 PF07897.6 EDN07435.1 - 4.7 6.9 10.2 5.3 6.8 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Syntaxin PF00804.20 EDN07436.1 - 0.015 15.4 0.2 0.042 14.0 0.0 1.7 1 1 1 2 2 2 0 Syntaxin HWE_HK PF07536.9 EDN07436.1 - 0.095 13.1 1.7 0.2 12.0 0.5 2.0 1 1 1 2 2 2 0 HWE histidine kinase Apolipoprotein PF01442.13 EDN07436.1 - 0.49 9.8 6.3 0.87 9.0 4.3 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Ldh_1_C PF02866.13 EDN07438.1 - 9.4e-44 149.1 0.0 1.8e-43 148.2 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EDN07438.1 - 8.5e-43 145.5 0.0 1.7e-42 144.5 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EDN07438.1 - 0.0014 17.3 0.0 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 EDN07438.1 - 0.067 12.2 0.1 0.65 9.0 0.0 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.11 EDN07438.1 - 0.13 11.5 0.1 1 8.6 0.1 2.3 1 1 0 2 2 2 0 Family 4 glycosyl hydrolase V-SNARE_C PF12352.3 EDN07439.1 - 1.6e-09 37.7 0.2 3.8e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Rho_N PF07498.7 EDN07439.1 - 0.095 12.4 0.4 4.8 7.0 0.0 2.9 3 0 0 3 3 3 0 Rho termination factor, N-terminal domain 2-oxoacid_dh PF00198.18 EDN07441.1 - 5.9e-76 254.7 0.3 7.4e-76 254.4 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EDN07441.1 - 8.8e-17 60.5 0.8 8.8e-17 60.5 0.6 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EDN07441.1 - 3.6e-14 52.0 0.3 9.1e-14 50.8 0.2 1.7 1 0 0 1 1 1 1 e3 binding domain Sec7 PF01369.15 EDN07442.1 - 7e-64 215.0 2.1 1.1e-63 214.3 0.3 2.2 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 EDN07442.1 - 2.2e-54 183.3 7.8 2.2e-54 183.3 5.4 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EDN07442.1 - 1.5e-29 101.3 2.1 1.1e-28 98.5 0.0 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) NAD_binding_7 PF13241.1 EDN07443.1 - 3e-32 110.9 0.0 4.4e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EDN07443.1 - 3.4e-29 99.9 0.0 5.1e-29 99.3 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EDN07443.1 - 4.2e-16 57.6 0.1 6.6e-16 56.9 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.16 EDN07443.1 - 0.16 11.7 0.4 0.49 10.2 0.0 1.9 1 1 1 2 2 2 0 ThiF family Pribosyltran_N PF13793.1 EDN07444.1 - 5.3e-31 106.7 0.1 5.8e-31 106.6 0.0 1.0 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EDN07445.1 - 6.1e-34 117.3 0.0 3.2e-29 101.9 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EDN07445.1 - 5.1e-07 29.4 0.0 5.9e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl transferase domain RVT_1 PF00078.22 EDN07447.1 - 2.4e-35 121.8 0.0 3.6e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN07447.1 - 1.5e-14 54.4 0.0 3.1e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 RNase H Pkinase PF00069.20 EDN07449.1 - 2.8e-17 62.7 0.0 1.5e-16 60.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07449.1 - 1.3e-07 30.9 0.0 1.7e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DUF4092 PF13322.1 EDN07450.1 - 0.047 13.4 0.1 0.057 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4092) Nucleoplasmin PF03066.10 EDN07451.1 - 0.028 13.9 0.1 0.04 13.4 0.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin RVT_1 PF00078.22 EDN07452.1 - 1.1e-35 123.0 0.0 1.6e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN07452.1 - 2.3e-14 53.8 0.0 5.6e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN07452.1 - 4.2e-11 42.4 0.0 9.3e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase AvrE PF11725.3 EDN07452.1 - 0.96 6.3 2.7 1.4 5.8 1.9 1.1 1 0 0 1 1 1 0 Pathogenicity factor p450 PF00067.17 EDN07453.1 - 4.3e-62 210.1 0.1 5.6e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_10 PF05971.7 EDN07454.1 - 4.1e-05 22.8 0.2 4.4e-05 22.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_10 PF05971.7 EDN07455.1 - 2.9e-23 82.4 0.0 3.6e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Complex1_LYR PF05347.10 EDN07456.1 - 2.4e-07 30.4 1.5 4.7e-07 29.5 0.5 1.9 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDN07456.1 - 5.8e-06 26.4 4.9 1.3e-05 25.2 3.4 1.9 1 1 0 1 1 1 1 Complex1_LYR-like Ank_4 PF13637.1 EDN07457.1 - 3.1e-13 49.8 1.3 1.1e-10 41.7 0.1 3.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDN07457.1 - 7e-06 26.2 0.2 0.0032 17.7 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EDN07457.1 - 0.00092 19.2 3.1 0.17 12.2 0.1 4.2 4 1 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 EDN07457.1 - 0.0015 18.7 2.5 0.1 12.8 0.1 3.7 3 1 0 3 3 3 1 Ankyrin repeats (many copies) KilA-N PF04383.8 EDN07457.1 - 0.003 17.1 0.3 0.017 14.7 0.2 2.2 1 1 0 1 1 1 1 KilA-N domain PLU-1 PF08429.6 EDN07457.1 - 0.0072 15.2 3.3 0.012 14.4 2.3 1.3 1 0 0 1 1 1 1 PLU-1-like protein Tuberculin PF12198.3 EDN07457.1 - 0.025 14.4 0.6 0.11 12.4 0.4 2.1 1 0 0 1 1 1 0 Theoretical tuberculin protein Phage_GP20 PF06810.6 EDN07457.1 - 0.15 11.4 10.8 0.047 13.1 4.5 2.2 3 0 0 3 3 3 0 Phage minor structural protein GP20 Exonuc_VII_L PF02601.10 EDN07457.1 - 0.25 10.5 3.2 0.44 9.6 2.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spore_III_AB PF09548.5 EDN07457.1 - 1.7 8.4 5.4 3.3 7.4 3.7 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Ank PF00023.25 EDN07457.1 - 2.8 7.8 6.2 11 6.0 0.1 4.2 4 1 0 4 4 4 0 Ankyrin repeat Rick_17kDa_Anti PF05433.10 EDN07458.1 - 0.00027 20.5 19.0 0.00054 19.5 13.1 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EDN07458.1 - 0.031 13.9 7.3 0.071 12.7 5.1 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain SR-25 PF10500.4 EDN07458.1 - 0.15 11.5 13.7 0.19 11.1 9.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 EDN07458.1 - 0.18 11.8 19.0 0.24 11.4 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF533 PF04391.7 EDN07458.1 - 0.56 9.5 5.0 0.97 8.7 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) PT-VENN PF04829.8 EDN07458.1 - 1 8.9 4.8 2.9 7.5 3.3 1.7 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif PAT1 PF09770.4 EDN07458.1 - 1.7 6.8 10.0 1.7 6.7 6.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BLVR PF06375.6 EDN07458.1 - 3.5 7.4 13.1 4.7 7.0 9.1 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF1275 PF06912.6 EDN07459.1 - 1.6e-32 112.3 7.3 1.9e-32 112.1 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3483 PF11982.3 EDN07459.1 - 0.0045 16.3 0.3 0.0077 15.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3483) AzlD PF05437.7 EDN07459.1 - 4.7 7.2 10.6 2.1 8.3 0.8 3.1 1 1 3 4 4 4 0 Branched-chain amino acid transport protein (AzlD) Oxidored_q6 PF01058.17 EDN07460.1 - 4e-21 74.9 0.0 5.9e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Pkinase PF00069.20 EDN07461.1 - 7.5e-17 61.3 0.0 1.1e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07461.1 - 1.2e-06 27.8 0.0 0.0002 20.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase ABC_tran PF00005.22 EDN07462.1 - 1.3e-46 158.3 0.0 1.3e-23 83.8 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EDN07462.1 - 3.2e-19 69.9 0.2 9e-05 22.5 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EDN07462.1 - 9.3e-16 57.7 0.0 1.2e-05 24.7 0.0 3.7 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDN07462.1 - 6.4e-10 38.4 0.0 0.0011 18.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EDN07462.1 - 1.8e-09 38.2 1.3 0.0006 20.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EDN07462.1 - 2.5e-07 31.5 0.0 0.0029 18.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EDN07462.1 - 3.5e-07 29.5 0.0 0.001 18.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EDN07462.1 - 2.3e-06 27.5 0.0 0.024 14.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 EDN07462.1 - 5.1e-06 26.1 0.0 0.21 11.0 0.0 3.2 3 0 0 3 3 3 2 AAA-like domain AAA_28 PF13521.1 EDN07462.1 - 5.2e-06 26.5 0.0 0.018 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EDN07462.1 - 5.4e-06 26.5 0.0 0.038 14.1 0.0 3.2 3 0 0 3 3 2 2 AAA domain ArgK PF03308.11 EDN07462.1 - 1.4e-05 24.0 0.1 0.073 11.8 0.0 2.6 2 0 0 2 2 2 2 ArgK protein AAA_15 PF13175.1 EDN07462.1 - 1.6e-05 24.1 4.1 0.68 8.9 0.0 4.7 3 2 2 5 5 5 2 AAA ATPase domain SbcCD_C PF13558.1 EDN07462.1 - 1.7e-05 24.6 0.0 0.037 13.9 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EDN07462.1 - 2.2e-05 24.7 0.1 0.19 12.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EDN07462.1 - 2.4e-05 24.3 0.1 0.42 10.5 0.0 3.7 4 0 0 4 4 3 2 AAA ATPase domain NACHT PF05729.7 EDN07462.1 - 3.1e-05 23.7 0.0 0.037 13.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.4 EDN07462.1 - 3.5e-05 23.3 0.0 0.12 11.8 0.0 3.0 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EDN07462.1 - 4.8e-05 23.5 0.0 0.41 10.8 0.0 3.9 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EDN07462.1 - 5.2e-05 23.1 0.0 0.005 16.6 0.0 2.8 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.12 EDN07462.1 - 5.9e-05 22.9 0.1 0.21 11.4 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function DUF87 Miro PF08477.8 EDN07462.1 - 0.0001 22.7 0.0 0.12 12.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_33 PF13671.1 EDN07462.1 - 0.00013 21.8 0.0 0.62 9.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EDN07462.1 - 0.00013 22.0 0.0 0.59 10.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 EDN07462.1 - 0.0002 21.0 0.0 1 9.0 0.0 3.1 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EDN07462.1 - 0.00032 20.6 0.0 2.1 8.2 0.0 3.6 4 0 0 4 4 3 1 AAA domain Arch_ATPase PF01637.13 EDN07462.1 - 0.00037 20.2 0.0 0.58 9.8 0.0 3.2 2 0 0 2 2 2 1 Archaeal ATPase AAA_13 PF13166.1 EDN07462.1 - 0.00097 17.7 3.5 1.3 7.4 0.0 3.7 4 1 0 4 4 3 2 AAA domain cobW PF02492.14 EDN07462.1 - 0.001 18.5 0.2 1.2 8.5 0.0 3.4 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 EDN07462.1 - 0.002 17.6 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 EDN07462.1 - 0.0035 16.9 0.1 3.1 7.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EDN07462.1 - 0.0035 16.7 0.0 3.3 7.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain HEAT_2 PF13646.1 EDN07462.1 - 0.005 17.0 5.2 5.9 7.2 0.0 4.0 1 1 3 4 4 4 0 HEAT repeats ATP_bind_1 PF03029.12 EDN07462.1 - 0.012 15.1 0.0 4.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 EDN07462.1 - 0.013 15.0 0.2 2.9 7.2 0.0 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF3385 PF11865.3 EDN07462.1 - 0.018 14.9 0.0 0.14 12.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Septin PF00735.13 EDN07462.1 - 0.022 13.8 0.1 2.3 7.1 0.0 3.0 3 0 0 3 3 3 0 Septin ParcG PF10274.4 EDN07462.1 - 0.022 14.6 1.5 0.28 11.0 0.1 2.7 1 1 2 3 3 3 0 Parkin co-regulated protein T2SE PF00437.15 EDN07462.1 - 0.022 13.6 0.0 2.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 EDN07462.1 - 0.028 13.2 0.0 0.5 9.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MutS_V PF00488.16 EDN07462.1 - 0.028 13.8 0.1 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 MutS domain V AAA_19 PF13245.1 EDN07462.1 - 0.032 13.9 0.1 5.6 6.7 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain IstB_IS21 PF01695.12 EDN07462.1 - 0.075 12.4 0.0 21 4.4 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_5 PF07728.9 EDN07462.1 - 0.086 12.5 0.0 17 5.1 0.0 3.3 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EDN07462.1 - 0.095 11.8 0.4 5.2 6.1 0.0 3.0 4 0 0 4 4 2 0 Magnesium chelatase, subunit ChlI TPR_11 PF13414.1 EDN07465.1 - 2.3e-16 59.1 1.4 5.4e-09 35.5 0.1 4.8 4 1 1 5 5 5 2 TPR repeat TPR_1 PF00515.23 EDN07465.1 - 1.9e-08 33.5 7.1 2.4e-05 23.7 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDN07465.1 - 5.1e-07 29.3 1.6 0.04 14.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDN07465.1 - 1.5e-05 24.5 18.0 5.4e-05 22.8 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDN07465.1 - 9.9e-05 21.8 2.6 0.078 12.7 0.0 3.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDN07465.1 - 0.00075 19.1 4.5 0.038 13.7 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN07465.1 - 0.0023 18.4 0.2 0.0023 18.4 0.1 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN07465.1 - 0.0034 17.9 0.1 0.0034 17.9 0.0 4.9 5 1 1 6 6 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN07465.1 - 0.012 15.9 0.2 0.012 15.9 0.2 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDN07465.1 - 0.018 14.9 11.6 0.82 9.6 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EDN07465.1 - 0.23 11.3 4.7 8.5 6.3 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat SIMPL PF04402.9 EDN07466.1 - 4.2e-34 118.2 2.8 4.7e-34 118.0 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Ribosomal_L1 PF00687.16 EDN07466.1 - 0.016 14.5 0.0 0.14 11.5 0.0 2.0 1 1 1 2 2 2 0 Ribosomal protein L1p/L10e family Acyltransferase PF01553.16 EDN07467.1 - 0.013 14.8 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Acyltransferase Lipase_3 PF01764.20 EDN07468.1 - 5.7e-21 74.6 0.0 1.1e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2360 PF10152.4 EDN07468.1 - 5.4 7.2 7.1 2 8.6 0.7 2.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) ILVD_EDD PF00920.16 EDN07469.1 - 3.9e-202 672.3 1.2 4.5e-202 672.0 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family DDE_1 PF03184.14 EDN07471.1 - 1.8e-51 174.3 0.0 3e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN07471.1 - 4.7e-11 42.3 0.0 9.4e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN07471.1 - 1.2e-08 34.3 0.1 2.9e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Pkinase PF00069.20 EDN07472.1 - 2.9e-29 101.9 0.0 1.7e-14 53.6 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07472.1 - 2.4e-13 49.7 0.0 1e-09 37.8 0.0 2.4 2 1 1 3 3 3 2 Protein tyrosine kinase Tad_C PF09977.4 EDN07472.1 - 0.026 15.5 0.0 0.072 14.1 0.0 1.7 1 0 0 1 1 1 0 Putative Tad-like Flp pilus-assembly Kinase-like PF14531.1 EDN07472.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Lin-8 PF03353.10 EDN07472.1 - 0.21 10.8 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF3666 PF12408.3 EDN07473.1 - 0.033 13.2 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase Tim17 PF02466.14 EDN07474.1 - 4.5e-27 94.6 2.3 5.7e-27 94.2 1.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DDE_1 PF03184.14 EDN07475.1 - 2.7e-52 177.0 0.0 4.9e-52 176.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN07475.1 - 3.4e-06 26.8 0.0 8.7e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN07475.1 - 4.1e-06 26.5 0.0 1.6e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Synthase_beta PF11421.3 EDN07476.1 - 0.091 13.4 1.2 0.27 11.9 0.9 1.8 1 0 0 1 1 1 0 ATP synthase F1 beta subunit DUF2428 PF10350.4 EDN07477.1 - 1.3e-64 217.7 0.0 2.5e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) PX PF00787.19 EDN07478.1 - 1e-18 67.1 0.0 3.4e-18 65.4 0.0 1.9 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EDN07478.1 - 1e-09 38.0 8.2 2.2e-05 23.8 0.3 2.1 2 0 0 2 2 2 2 Vps5 C terminal like HTH_8 PF02954.14 EDN07478.1 - 0.071 12.6 0.2 0.58 9.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family UCH PF00443.24 EDN07479.1 - 1.3e-80 270.3 0.0 4.7e-80 268.5 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDN07479.1 - 7.4e-15 55.1 0.0 1.2e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EDN07479.1 - 2.6e-14 53.4 0.0 8.7e-14 51.7 0.0 2.0 1 0 0 1 1 1 1 DUSP domain USP7_C2 PF14533.1 EDN07479.1 - 0.023 14.1 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Sugar_tr PF00083.19 EDN07480.1 - 1e-74 251.7 21.8 1.3e-74 251.3 15.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN07480.1 - 1.7e-09 36.8 20.5 1.7e-09 36.8 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SYS1 PF09801.4 EDN07480.1 - 0.0093 15.9 1.5 0.021 14.8 0.1 2.2 2 0 0 2 2 2 1 Integral membrane protein S linking to the trans Golgi network Abhydrolase_6 PF12697.2 EDN07482.1 - 2.1e-06 27.8 0.0 2.3e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN07482.1 - 0.036 13.8 0.0 0.044 13.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Kinesin PF00225.18 EDN07483.1 - 4.6e-103 344.4 0.9 4.6e-103 344.4 0.6 2.2 2 1 0 2 2 2 1 Kinesin motor domain Apolipoprotein PF01442.13 EDN07483.1 - 0.089 12.2 30.2 0.034 13.6 16.3 2.5 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain ADSL_C PF10397.4 EDN07483.1 - 6.3 6.8 10.3 11 6.1 0.7 3.8 3 1 0 3 3 3 0 Adenylosuccinate lyase C-terminus DUF1900 PF08954.6 EDN07484.1 - 1.7e-37 128.0 0.0 7.2e-37 125.9 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EDN07484.1 - 5.4e-35 118.8 0.1 9.7e-35 118.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EDN07484.1 - 8.4e-17 60.3 0.6 6.9e-07 28.9 0.1 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat zf-C3HC4_3 PF13920.1 EDN07486.1 - 0.044 13.4 14.7 0.089 12.4 10.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EDN07486.1 - 0.91 9.3 8.3 1.7 8.5 5.7 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein CBFD_NFYB_HMF PF00808.18 EDN07487.1 - 1.6e-14 53.6 2.9 2.4e-14 53.1 2.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDN07487.1 - 2.3e-07 30.8 1.2 3.6e-07 30.2 0.8 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAT1 PF09770.4 EDN07487.1 - 3.8 5.6 11.5 4 5.5 8.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RAI16-like PF10257.4 EDN07488.1 - 5.2e-90 301.9 0.0 7.1e-90 301.4 0.0 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein Tom37_C PF11801.3 EDN07489.1 - 0.0064 16.3 0.4 0.0064 16.3 0.3 2.2 2 0 0 2 2 2 1 Tom37 C-terminal domain ATP-synt_E PF05680.7 EDN07489.1 - 2.2 8.2 5.3 0.94 9.4 1.2 2.2 2 0 0 2 2 2 0 ATP synthase E chain Myb_DNA-binding PF00249.26 EDN07491.1 - 0.00053 19.9 0.1 0.0011 18.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF573 PF04504.9 EDN07491.1 - 0.0013 18.9 0.7 0.0043 17.3 0.5 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF573 Myb_DNA-bind_6 PF13921.1 EDN07491.1 - 0.0052 16.8 1.4 0.0088 16.1 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDN07491.1 - 0.034 14.2 2.3 0.48 10.5 1.6 2.5 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF3505 PF12013.3 EDN07492.1 - 6e-14 52.2 1.5 6e-14 52.2 1.0 3.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3505) DUF3505 PF12013.3 EDN07493.1 - 9e-39 132.0 5.9 9e-39 132.0 4.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3505) YkuI_C PF10388.4 EDN07493.1 - 0.19 11.3 2.6 0.54 9.9 0.1 2.1 2 0 0 2 2 2 0 EAL-domain associated signalling protein domain DUF3505 PF12013.3 EDN07494.1 - 6.9e-16 58.4 0.3 8.4e-15 54.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) APH PF01636.18 EDN07496.1 - 9.3e-15 55.0 0.1 1.3e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DDE_1 PF03184.14 EDN07497.1 - 2.6e-52 177.1 0.0 4.8e-52 176.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN07497.1 - 3.3e-06 26.9 0.0 8.6e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN07497.1 - 4.1e-06 26.4 0.0 1.6e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EDN07498.1 - 3.1e-36 124.5 0.0 4.7e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN07498.1 - 1.3e-05 24.8 0.0 3.3e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN07498.1 - 0.0016 17.9 0.6 0.0034 16.8 0.4 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_Tnp_1_7 PF13843.1 EDN07499.1 - 1.2e-17 64.0 0.1 4.6e-14 52.2 0.0 2.0 1 1 1 2 2 2 2 Transposase IS4 DUF972 PF06156.8 EDN07501.1 - 0.15 12.3 2.2 0.32 11.3 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Myb_DNA-binding PF00249.26 EDN07503.1 - 0.00051 20.0 0.1 0.0011 18.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF573 PF04504.9 EDN07503.1 - 0.0013 18.9 0.7 0.0043 17.3 0.5 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF573 Myb_DNA-bind_6 PF13921.1 EDN07503.1 - 0.0051 16.8 1.4 0.0088 16.1 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDN07503.1 - 0.034 14.2 2.3 0.48 10.5 1.6 2.5 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain RVT_1 PF00078.22 EDN07504.1 - 2e-25 89.4 0.0 2.8e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3435 PF11917.3 EDN07509.1 - 1.8e-20 73.1 0.0 2.7e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-Di19 PF05605.7 EDN07509.1 - 0.21 11.7 2.1 0.59 10.3 0.4 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding POX PF07526.6 EDN07510.1 - 0.0024 18.1 0.5 0.0032 17.6 0.4 1.2 1 0 0 1 1 1 1 Associated with HOX HNF-1_N PF04814.8 EDN07510.1 - 0.37 10.8 2.0 0.46 10.5 1.4 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus EBV-NA3 PF05009.7 EDN07510.1 - 0.39 9.9 4.4 0.44 9.7 3.1 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CDC45 PF02724.9 EDN07510.1 - 0.67 7.9 9.5 0.72 7.8 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 EDN07510.1 - 1.1 8.8 5.9 1.2 8.6 4.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.6 EDN07510.1 - 1.7 6.6 6.5 2 6.4 4.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ste5 PF11610.3 EDN07512.1 - 0.058 12.9 11.2 0.71 9.4 0.0 5.3 6 0 0 6 6 6 0 Scaffold protein Ste5-Fus5 binding region DUF2244 PF10003.4 EDN07512.1 - 7.2 5.9 6.7 5.6 6.3 0.3 3.1 2 2 2 4 4 4 0 Integral membrane protein (DUF2244) Ricin_B_lectin PF00652.17 EDN07515.1 - 0.13 12.2 2.5 0.42 10.6 1.8 1.7 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain DUF3505 PF12013.3 EDN07516.1 - 6e-38 129.4 5.6 6e-38 129.4 3.9 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3505) Tom37_C PF11801.3 EDN07516.1 - 0.02 14.7 1.4 0.02 14.7 1.0 2.5 2 0 0 2 2 2 0 Tom37 C-terminal domain Nucleoplasmin PF03066.10 EDN07516.1 - 0.36 10.3 11.7 0.041 13.3 4.8 1.9 2 0 0 2 2 2 0 Nucleoplasmin TRAP_alpha PF03896.11 EDN07516.1 - 1.3 7.9 6.5 2.7 6.9 4.5 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pox_RNA_Pol_19 PF05320.7 EDN07516.1 - 2.4 7.8 10.5 6 6.5 4.2 2.3 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Spore_coat_CotO PF14153.1 EDN07516.1 - 4.9 6.5 21.5 0.54 9.6 5.5 2.4 2 0 0 2 2 2 0 Spore coat protein CotO DUF1041 PF06292.12 EDN07517.1 - 0.77 9.9 5.6 8.1 6.6 0.3 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) DUF3505 PF12013.3 EDN07519.1 - 0.00048 20.3 0.0 0.00056 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Trypan_PARP PF05887.6 EDN07522.1 - 0.99 9.2 4.8 1.9 8.2 3.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3505 PF12013.3 EDN07525.1 - 1.7e-15 57.1 0.1 5e-15 55.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) rve PF00665.21 EDN07526.1 - 4.6e-16 59.0 0.0 1e-15 57.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN07526.1 - 0.013 15.1 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain DUF4219 PF13961.1 EDN07526.1 - 0.028 13.8 0.2 0.028 13.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) zf-CCHC PF00098.18 EDN07526.1 - 2.9 7.9 4.3 5.2 7.1 3.0 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3505 PF12013.3 EDN07528.1 - 1.6e-05 25.1 2.9 1.6e-05 25.1 2.0 3.5 5 1 1 6 6 6 1 Protein of unknown function (DUF3505) DUF3505 PF12013.3 EDN07529.1 - 1.5e-11 44.4 2.6 1.8e-11 44.2 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) DEAD PF00270.24 EDN07529.1 - 3.4e-11 42.9 0.0 1.3e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.9 EDN07529.1 - 0.02 13.4 0.0 0.036 12.6 0.0 1.3 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer ResIII PF04851.10 EDN07529.1 - 0.021 14.6 0.0 0.18 11.5 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DDE_1 PF03184.14 EDN07531.1 - 3.4e-83 278.0 0.0 9.2e-51 172.0 0.0 3.4 2 1 1 3 3 3 3 DDE superfamily endonuclease DDE_3 PF13358.1 EDN07531.1 - 4.5e-09 36.1 0.0 1.3e-05 25.0 0.0 3.3 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN07531.1 - 7.7e-07 28.8 0.0 0.0048 16.6 0.0 2.5 2 0 0 2 2 2 2 Tc5 transposase DNA-binding domain LINES_C PF14695.1 EDN07531.1 - 0.022 14.0 0.1 4.9 6.4 0.0 3.0 3 0 0 3 3 3 0 Lines C-terminus Phenol_hyd_sub PF06099.6 EDN07531.1 - 0.039 13.7 0.1 6.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Phenol hydroxylase subunit MBD_C PF14048.1 EDN07531.1 - 0.23 12.0 4.0 13 6.4 0.1 2.7 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 Nucleoplasmin PF03066.10 EDN07533.1 - 0.16 11.5 4.6 0.18 11.3 3.2 1.1 1 0 0 1 1 1 0 Nucleoplasmin zf-DHHC PF01529.15 EDN07533.1 - 0.28 10.5 1.2 0.34 10.2 0.8 1.0 1 0 0 1 1 1 0 DHHC palmitoyltransferase Trypan_PARP PF05887.6 EDN07533.1 - 0.32 10.7 6.0 0.33 10.7 4.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Borrelia_P83 PF05262.6 EDN07533.1 - 0.37 9.0 2.4 0.39 8.9 1.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein RNA_pol_Rpo13 PF12136.3 EDN07533.1 - 4 7.2 10.2 57 3.5 6.2 2.1 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain DUF3505 PF12013.3 EDN07534.1 - 1e-37 128.6 5.9 1e-37 128.6 4.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3505) DEAD PF00270.24 EDN07534.1 - 1.4e-15 57.1 0.0 3.5e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN07534.1 - 4.5e-06 26.6 2.6 5e-05 23.2 0.0 3.4 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDN07534.1 - 0.0063 15.3 0.8 0.058 12.1 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Tom37_C PF11801.3 EDN07534.1 - 1.5 8.6 10.3 0.048 13.5 1.3 2.6 2 0 0 2 2 2 0 Tom37 C-terminal domain TRAP_alpha PF03896.11 EDN07534.1 - 5.5 5.8 7.2 13 4.6 5.0 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit C2 PF00168.25 EDN07535.1 - 1.2e-10 41.0 0.2 3.5e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 C2 domain Pkinase PF00069.20 EDN07536.1 - 5.6e-62 209.2 0.0 7.9e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07536.1 - 3e-33 115.0 0.0 4.5e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN07536.1 - 0.062 13.0 0.1 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EDN07536.1 - 0.1 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like IGR PF09597.5 EDN07537.1 - 4e-21 74.6 0.1 6.4e-21 74.0 0.1 1.3 1 0 0 1 1 1 1 IGR protein motif p450 PF00067.17 EDN07538.1 - 1.4e-67 228.2 0.0 1.7e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 K-box PF01486.12 EDN07538.1 - 0.023 14.4 0.1 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 K-box region DUF3684 PF12449.3 EDN07538.1 - 0.026 12.1 0.0 0.036 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) Pkinase PF00069.20 EDN07539.1 - 4.1e-68 229.3 0.0 6.5e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07539.1 - 3.7e-29 101.5 0.0 5.3e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EDN07539.1 - 3.2e-17 62.3 0.2 7.4e-17 61.2 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EDN07539.1 - 5e-05 22.3 0.1 0.00031 19.8 0.0 2.2 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EDN07539.1 - 0.0011 18.7 0.1 0.0069 16.1 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EDN07539.1 - 0.0045 16.0 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EDN07539.1 - 0.045 12.5 0.1 0.074 11.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EDN07539.1 - 0.16 11.2 0.1 0.43 9.8 0.0 1.5 1 1 0 2 2 2 0 RIO1 family PI3_PI4_kinase PF00454.22 EDN07540.1 - 8e-35 120.4 0.0 4.3e-34 118.0 0.0 2.2 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EDN07540.1 - 2.8e-24 85.3 0.2 7.2e-24 83.9 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) YTH PF04146.10 EDN07542.1 - 1.3e-35 122.0 0.0 2.8e-32 111.2 0.0 2.3 1 1 1 2 2 2 2 YT521-B-like domain RRM_6 PF14259.1 EDN07542.1 - 1.9e-06 27.7 0.0 3.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN07542.1 - 5.1e-06 26.0 0.0 9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN07542.1 - 0.037 13.8 0.1 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribonuclease PF00545.15 EDN07543.1 - 0.043 13.8 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 ribonuclease ArfGap PF01412.13 EDN07544.1 - 3.2e-33 113.9 0.1 3.2e-33 113.9 0.0 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EDN07544.1 - 2.8e-13 49.9 0.1 2.8e-13 49.9 0.1 2.1 2 0 0 2 2 2 1 PH domain EMP24_GP25L PF01105.19 EDN07544.1 - 0.048 13.3 1.2 0.28 10.8 0.8 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF3435 PF11917.3 EDN07546.1 - 3e-154 513.7 0.0 3.9e-154 513.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2_4 PF13894.1 EDN07546.1 - 0.22 11.9 4.2 7.8 7.0 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger RVT_2 PF07727.9 EDN07547.1 - 1.8e-71 239.9 0.0 2.9e-71 239.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN07547.1 - 2.9e-16 59.6 0.0 1.1e-15 57.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EDN07547.1 - 1.1e-07 31.3 0.0 2.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 EDN07547.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EDN07547.1 - 0.046 13.1 0.1 0.14 11.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Abhydrolase_6 PF12697.2 EDN07548.1 - 0.00086 19.2 0.3 0.00086 19.2 0.2 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Pectate_lyase_3 PF12708.2 EDN07550.1 - 5.6e-50 170.5 12.5 4.3e-42 144.7 1.5 3.1 3 0 0 3 3 3 2 Pectate lyase superfamily protein Peptidase_S8 PF00082.17 EDN07550.1 - 2.7e-15 56.2 0.0 8.7e-15 54.6 0.0 1.8 2 0 0 2 2 2 1 Subtilase family BNR_assoc_N PF14873.1 EDN07550.1 - 0.049 13.4 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of BNR-repeat neuraminidase HALZ PF02183.13 EDN07551.1 - 1.1e-05 25.0 1.1 2.2e-05 24.0 0.7 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper CALCOCO1 PF07888.6 EDN07551.1 - 0.0091 14.3 0.1 0.014 13.6 0.0 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF904 PF06005.7 EDN07551.1 - 0.013 15.7 0.2 0.025 14.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Cortex-I_coil PF09304.5 EDN07551.1 - 0.015 15.3 0.6 0.032 14.2 0.2 1.7 2 0 0 2 2 2 0 Cortexillin I, coiled coil ATG16 PF08614.6 EDN07551.1 - 0.064 13.0 0.2 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 EDN07551.1 - 0.067 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4618 PF15397.1 EDN07551.1 - 0.07 12.4 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) bZIP_1 PF00170.16 EDN07551.1 - 0.11 12.5 1.1 0.27 11.2 0.8 1.6 1 0 0 1 1 1 0 bZIP transcription factor TSC22 PF01166.13 EDN07551.1 - 0.16 11.9 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Myb_DNA-binding PF00249.26 EDN07552.1 - 5e-10 39.2 0.7 7.9e-10 38.6 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN07552.1 - 1e-06 28.7 0.9 1.9e-06 27.8 0.6 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain BH4 PF02180.12 EDN07552.1 - 0.084 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Bcl-2 homology region 4 IFR3_antag PF14754.1 EDN07552.1 - 0.14 11.1 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 Papain-like auto-proteinase BCS1_N PF08740.6 EDN07553.1 - 2.2e-40 138.2 0.0 3.6e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN07553.1 - 1.7e-19 70.3 0.0 5.6e-19 68.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN07553.1 - 0.00035 20.6 0.5 0.00085 19.3 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EDN07553.1 - 0.0067 17.2 0.0 0.041 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN07553.1 - 0.012 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDN07553.1 - 0.052 13.2 0.0 0.16 11.7 0.0 1.8 1 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN07553.1 - 0.068 13.3 0.0 0.31 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EDN07553.1 - 0.074 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.1 EDN07553.1 - 0.084 12.7 0.1 0.52 10.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EDN07553.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain RVT_1 PF00078.22 EDN07556.1 - 1.4e-34 119.3 0.0 2.2e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN07556.1 - 2.4e-15 56.1 0.0 1e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN07556.1 - 0.00055 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 EDN07557.1 - 5.5e-08 32.2 0.1 0.00069 18.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07557.1 - 0.034 13.2 0.1 1.5 7.7 0.0 2.0 1 1 1 2 2 2 0 Protein tyrosine kinase Rad60-SLD PF11976.3 EDN07560.1 - 3.7e-23 81.0 0.0 3.9e-20 71.3 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EDN07560.1 - 0.031 13.6 0.0 0.34 10.3 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin family LSM PF01423.17 EDN07561.1 - 7e-19 67.1 0.0 7.8e-19 66.9 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDN07561.1 - 0.0031 17.3 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain IF-2B PF01008.12 EDN07562.1 - 1.1e-70 237.8 0.2 1.3e-70 237.6 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family RAMP4 PF06624.7 EDN07563.1 - 7.5e-05 22.1 0.0 9e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 CoA_binding_3 PF13727.1 EDN07563.1 - 0.095 12.5 0.3 0.11 12.2 0.2 1.1 1 0 0 1 1 1 0 CoA-binding domain Adaptin_N PF01602.15 EDN07564.1 - 6.9e-53 179.7 0.0 1.3e-52 178.8 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 EDN07564.1 - 5.1e-05 23.0 1.1 2.3 8.5 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat Med19 PF10278.4 EDN07564.1 - 4.6 6.8 19.4 0.44 10.2 5.9 3.0 3 0 0 3 3 3 0 Mediator of RNA pol II transcription subunit 19 TPR_14 PF13428.1 EDN07565.1 - 3.4e-09 36.5 2.5 0.026 15.1 0.0 4.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EDN07565.1 - 8.2e-09 34.9 2.5 5.1e-05 22.8 0.4 3.3 2 1 1 4 4 4 2 TPR repeat TPR_17 PF13431.1 EDN07565.1 - 1.3e-08 34.3 0.0 6e-05 22.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN07565.1 - 7e-08 32.6 1.6 0.0015 18.8 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN07565.1 - 2.3e-06 28.1 2.9 0.34 11.6 0.2 3.9 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EDN07565.1 - 7.9e-06 25.2 3.7 1.1e-05 24.8 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDN07565.1 - 4.7e-05 22.9 3.1 0.0032 17.2 0.2 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDN07565.1 - 8.7e-05 22.3 0.2 0.27 11.1 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDN07565.1 - 0.0019 17.8 2.0 1.7 8.6 0.1 3.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDN07565.1 - 0.012 16.0 0.9 12 6.5 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDN07565.1 - 0.012 15.2 0.2 0.22 11.3 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EDN07565.1 - 0.013 15.3 1.3 0.079 12.8 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_3 PF13812.1 EDN07565.1 - 0.017 15.3 0.0 0.091 13.0 0.0 2.3 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Syja_N PF02383.13 EDN07567.1 - 5.9e-83 278.2 0.0 9.2e-83 277.6 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EDN07567.1 - 2.7e-28 99.5 0.1 5.6e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rer1 PF03248.8 EDN07568.1 - 0.1 12.1 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Rer1 family G-patch PF01585.18 EDN07569.1 - 7.7e-05 22.3 0.1 0.00063 19.4 0.1 2.4 1 1 0 1 1 1 1 G-patch domain DUF572 PF04502.8 EDN07569.1 - 0.82 8.8 21.9 1.1 8.4 15.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Surp PF01805.15 EDN07570.1 - 0.069 12.8 0.6 0.51 10.0 0.0 2.5 3 0 0 3 3 3 0 Surp module DAGAT PF03982.8 EDN07571.1 - 2.8e-92 308.5 0.0 3.7e-92 308.1 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 EDN07571.1 - 0.0074 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Rer1 family Kinesin PF00225.18 EDN07573.1 - 1e-97 326.8 0.3 2.7e-97 325.4 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain DNA_ligase_OB PF03120.11 EDN07573.1 - 0.094 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain N-SET PF11764.3 EDN07574.1 - 6.6e-53 179.0 0.8 6.6e-53 179.0 0.6 2.2 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EDN07574.1 - 6e-26 89.5 0.9 1.2e-25 88.6 0.6 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EDN07574.1 - 4.4e-24 85.6 0.2 4.4e-24 85.6 0.1 4.0 4 2 0 4 4 4 1 SET domain RRM_1 PF00076.17 EDN07574.1 - 0.00013 21.5 0.0 0.00027 20.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.23 EDN07575.1 - 3.9e-136 453.7 0.0 5.6e-71 239.1 0.0 3.2 2 1 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EDN07575.1 - 1.2e-90 303.4 0.0 3.1e-38 131.3 0.0 3.4 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 EDN07575.1 - 6.9e-31 106.3 0.1 1.2e-10 41.4 0.0 4.0 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EDN07575.1 - 2.2e-11 44.5 0.0 0.00015 22.5 0.0 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Csm1 PF12539.3 EDN07575.1 - 0.0034 17.8 0.1 1.7 9.1 0.0 2.9 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 Tox-SHH PF15652.1 EDN07575.1 - 0.16 12.5 0.0 0.74 10.4 0.0 2.1 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature TPM PF04536.9 EDN07575.1 - 0.2 11.5 0.1 0.84 9.5 0.0 2.1 2 0 0 2 2 2 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase AATase PF07247.7 EDN07575.1 - 1.3 7.5 2.6 62 1.9 0.0 3.6 5 0 0 5 5 5 0 Alcohol acetyltransferase AMP-binding PF00501.23 EDN07576.1 - 1.2e-65 221.5 0.0 2.4e-65 220.5 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.15 EDN07576.1 - 1.4e-49 168.6 0.3 1.3e-27 96.4 0.0 4.1 3 1 1 4 4 4 4 Condensation domain PP-binding PF00550.20 EDN07576.1 - 4.2e-11 42.9 2.8 7.1e-11 42.2 0.0 2.7 3 0 0 3 3 3 1 Phosphopantetheine attachment site MFS_1 PF07690.11 EDN07577.1 - 8.1e-21 74.1 27.9 8.1e-21 74.1 19.3 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN07577.1 - 9.2e-06 24.1 5.3 9.2e-06 24.1 3.7 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2457 PF10446.4 EDN07577.1 - 2.2 6.9 7.8 2.9 6.4 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TauE PF01925.14 EDN07577.1 - 2.9 7.2 36.5 0.31 10.4 15.0 2.9 2 1 1 3 3 3 0 Sulfite exporter TauE/SafE SIS PF01380.17 EDN07578.1 - 5.8e-54 181.2 0.0 1.4e-29 102.2 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EDN07578.1 - 3.8e-23 81.7 0.0 1.9e-17 63.0 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EDN07578.1 - 7.5e-19 68.0 0.0 1.5e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EDN07578.1 - 2e-11 43.6 0.0 4.3e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EDN07578.1 - 1.3e-06 27.3 0.0 2.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EDN07578.1 - 0.04 13.6 0.0 0.26 10.9 0.0 2.3 2 0 0 2 2 2 0 SIS domain DMRL_synthase PF00885.14 EDN07579.1 - 3.8e-42 143.3 0.0 4.9e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Proteasome PF00227.21 EDN07580.1 - 2.2e-45 154.3 0.0 3.5e-32 111.2 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EDN07580.1 - 6.9e-12 44.4 0.0 1.5e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Zn-ribbon_8 PF09723.5 EDN07581.1 - 0.031 14.2 1.5 0.092 12.7 0.6 2.0 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 EDN07581.1 - 1.8 7.8 5.0 0.92 8.8 1.5 2.0 2 1 0 2 2 2 0 zinc-ribbon domain Iso_dh PF00180.15 EDN07583.1 - 7.1e-73 245.5 0.0 8.3e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Copine PF07002.11 EDN07583.1 - 0.077 12.7 0.0 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 Copine WBS_methylT PF12589.3 EDN07584.1 - 2e-18 66.6 0.8 3.2e-18 65.9 0.6 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EDN07584.1 - 3.4e-10 40.2 0.0 5.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN07584.1 - 1.4e-07 31.7 0.0 2.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN07584.1 - 8.3e-06 25.4 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN07584.1 - 4.1e-05 24.1 0.0 8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN07584.1 - 5.4e-05 23.6 0.0 0.00014 22.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN07584.1 - 9.4e-05 22.1 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDN07584.1 - 0.00016 21.3 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EDN07584.1 - 0.0013 18.7 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN07584.1 - 0.0032 16.6 0.0 0.0096 15.0 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EDN07584.1 - 0.071 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EDN07584.1 - 0.17 10.9 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Erv26 PF04148.8 EDN07585.1 - 1.6e-88 295.5 1.7 1.9e-88 295.3 1.2 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Ferric_reduct PF01794.14 EDN07585.1 - 0.0012 18.9 5.0 0.013 15.5 3.5 2.2 1 1 0 1 1 1 1 Ferric reductase like transmembrane component RhoGAP PF00620.22 EDN07587.1 - 2.1e-39 134.5 0.0 5.4e-39 133.2 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EDN07587.1 - 7.7e-13 48.5 0.1 4.7e-12 46.0 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EDN07587.1 - 3.7e-10 40.0 0.0 8e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EDN07587.1 - 0.0077 16.2 0.0 0.034 14.2 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain MDM31_MDM32 PF08118.6 EDN07589.1 - 3.8e-190 632.6 0.0 5e-190 632.2 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_1 PF00013.24 EDN07590.1 - 0.00029 20.3 1.4 0.00074 19.1 0.8 1.8 2 0 0 2 2 2 1 KH domain Proteasome PF00227.21 EDN07591.1 - 1.8e-31 108.9 0.2 3.6e-31 107.9 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit RVT_1 PF00078.22 EDN07595.1 - 1.6e-24 86.5 0.0 3.3e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN07595.1 - 1.1e-19 70.6 0.5 4.8e-19 68.6 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain Chromo PF00385.19 EDN07595.1 - 1.6e-13 50.1 2.5 2.3e-13 49.6 0.7 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.18 EDN07595.1 - 9.1e-06 25.3 0.4 1.9e-05 24.3 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-H2C2 PF09337.5 EDN07595.1 - 0.033 13.5 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger Mtf2_C PF14061.1 EDN07595.1 - 0.047 13.5 0.6 0.16 11.8 0.1 2.0 1 1 1 2 2 2 0 Polycomb-like MTF2 factor 2 zf-CCHC_4 PF14392.1 EDN07595.1 - 0.13 11.9 1.5 0.35 10.5 1.0 1.7 1 0 0 1 1 1 0 Zinc knuckle HCNGP PF07818.8 EDN07596.1 - 6.9e-35 118.9 0.2 1.5e-34 117.8 0.1 1.6 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.21 EDN07597.1 - 7.8e-28 97.0 0.0 9.3e-28 96.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit FAA_hydrolase PF01557.13 EDN07598.1 - 1.4e-62 211.0 0.0 1.9e-62 210.5 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.10 EDN07599.1 - 1.9e-15 56.3 2.6 2.3e-15 56.1 1.8 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDN07599.1 - 3.6e-12 46.3 2.5 4.4e-12 46.0 1.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EDN07599.1 - 0.004 17.6 0.5 0.0051 17.2 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF4186 PF13811.1 EDN07599.1 - 0.036 13.7 0.1 0.045 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4186) RVT_2 PF07727.9 EDN07600.1 - 1.7e-19 69.7 0.0 2.8e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HSP20 PF00011.16 EDN07601.1 - 2.4e-19 69.0 0.1 1.8e-12 46.9 0.0 2.3 1 1 1 2 2 2 2 Hsp20/alpha crystallin family CENP-T PF15511.1 EDN07603.1 - 0.0028 16.9 6.4 0.0033 16.7 4.5 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Autophagy_act_C PF03987.10 EDN07603.1 - 0.004 17.3 0.1 0.0073 16.4 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain CDC45 PF02724.9 EDN07603.1 - 0.035 12.1 10.1 0.038 12.0 7.0 1.0 1 0 0 1 1 1 0 CDC45-like protein SPX PF03105.14 EDN07603.1 - 0.04 13.6 0.5 0.046 13.4 0.4 1.1 1 0 0 1 1 1 0 SPX domain Nop14 PF04147.7 EDN07603.1 - 0.045 11.6 17.3 0.05 11.5 12.0 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 EDN07603.1 - 0.068 11.2 9.8 0.08 11.0 6.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.8 EDN07603.1 - 0.17 9.6 18.7 0.19 9.4 13.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.6 EDN07603.1 - 0.17 11.3 15.2 0.22 11.0 10.6 1.1 1 0 0 1 1 1 0 PPP4R2 Vfa1 PF08432.5 EDN07603.1 - 0.18 11.7 4.7 0.23 11.4 3.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.7 EDN07603.1 - 0.27 10.4 13.9 0.32 10.2 9.7 1.1 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 EDN07603.1 - 0.87 8.2 32.7 1.1 7.8 22.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BTV_NS2 PF04514.7 EDN07603.1 - 1.2 7.9 7.1 1.5 7.6 4.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Nop25 PF09805.4 EDN07603.1 - 1.4 9.0 7.4 2 8.4 5.1 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Cwf_Cwc_15 PF04889.7 EDN07603.1 - 2.1 7.9 21.2 3.2 7.3 14.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1510 PF07423.6 EDN07603.1 - 2.3 7.5 10.3 3.2 7.0 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FYDLN_acid PF09538.5 EDN07603.1 - 4.1 8.0 27.6 7.3 7.2 19.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF2722 PF10846.3 EDN07603.1 - 7.9 5.3 7.8 9.1 5.1 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TRAP_alpha PF03896.11 EDN07603.1 - 9.3 5.1 10.8 13 4.6 7.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.7 EDN07603.1 - 9.6 5.3 21.4 12 4.9 14.8 1.1 1 0 0 1 1 1 0 NOA36 protein RRM_5 PF13893.1 EDN07604.1 - 1.9e-09 37.2 0.1 2.6e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN07604.1 - 7.8e-09 35.0 0.1 1.7e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN07604.1 - 7.8e-05 22.5 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EDN07604.1 - 0.0034 17.0 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Calcipressin WD40 PF00400.27 EDN07605.1 - 2.5e-17 62.0 11.5 0.00041 20.1 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Rax2 PF12768.2 EDN07605.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Gmad1 PF10647.4 EDN07605.1 - 0.002 17.5 0.1 0.4 10.0 0.0 3.3 3 1 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EDN07605.1 - 0.038 13.6 0.1 0.33 10.6 0.1 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DDE_1 PF03184.14 EDN07606.1 - 1.9e-36 125.2 0.0 3.5e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN07606.1 - 1.9e-05 24.4 0.0 6e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN07606.1 - 0.0057 16.1 0.6 0.0057 16.1 0.4 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain TraG_N PF07916.6 EDN07606.1 - 0.78 8.1 3.6 1.1 7.5 2.5 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF2229 PF09989.4 EDN07606.1 - 4.6 6.6 8.7 39 3.5 6.0 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) zf-C2H2 PF00096.21 EDN07608.1 - 0.00027 21.0 0.8 0.00027 21.0 0.5 2.6 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EDN07608.1 - 0.0008 19.2 0.4 0.002 17.9 0.3 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger EST1_DNA_bind PF10373.4 EDN07608.1 - 0.035 13.3 0.1 0.075 12.2 0.0 1.6 1 1 0 1 1 1 0 Est1 DNA/RNA binding domain TPR_17 PF13431.1 EDN07608.1 - 0.1 12.8 0.0 0.77 10.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.1 EDN07608.1 - 0.66 10.4 6.8 0.084 13.2 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_tranf_2_3 PF13641.1 EDN07609.1 - 6.1e-26 91.6 0.0 1.3e-25 90.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EDN07609.1 - 1.1e-09 37.7 0.0 2.9e-09 36.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EDN07609.1 - 7.5e-08 32.2 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 ThiF PF00899.16 EDN07609.1 - 0.022 14.5 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 ThiF family Ank_4 PF13637.1 EDN07610.1 - 2.4e-19 69.2 0.6 1.2e-07 32.0 0.0 4.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDN07610.1 - 1e-16 60.9 0.0 8.6e-11 42.0 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EDN07610.1 - 7.7e-14 50.7 1.7 0.015 15.0 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EDN07610.1 - 1.5e-10 40.9 4.8 0.0001 22.4 0.0 5.1 4 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN07610.1 - 1.6e-08 33.9 0.6 1.1 9.7 0.0 6.2 6 0 0 6 6 6 2 Ankyrin repeat 7TMR-DISM_7TM PF07695.6 EDN07611.1 - 0.64 9.6 12.0 0.07 12.7 2.2 2.2 1 1 0 2 2 2 0 7TM diverse intracellular signalling Pkinase PF00069.20 EDN07614.1 - 5e-07 29.1 0.0 9.3e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EDN07614.1 - 0.00027 20.0 0.0 0.00054 19.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN07614.1 - 0.003 17.3 2.1 0.0085 15.8 0.1 2.7 2 1 0 3 3 3 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.1 EDN07614.1 - 0.006 16.3 0.0 0.58 9.9 0.0 2.5 2 0 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) Chromo PF00385.19 EDN07615.1 - 0.00058 19.4 0.1 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Glyco_hydro_43 PF04616.9 EDN07617.1 - 7.7e-25 87.5 0.3 1.1e-24 86.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Lipase_3 PF01764.20 EDN07618.1 - 3.5e-32 110.9 0.0 5.4e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EDN07618.1 - 0.0024 17.6 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EDN07618.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.2 EDN07618.1 - 0.034 14.0 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EDN07618.1 - 0.035 13.6 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 EDN07618.1 - 0.052 13.0 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PBP1_TM PF14812.1 EDN07618.1 - 0.088 13.1 3.9 0.19 12.0 2.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2974 PF11187.3 EDN07618.1 - 0.099 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1455 PF07306.6 EDN07619.1 - 0.0062 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1455) PhoD PF09423.5 EDN07619.1 - 0.044 12.3 0.1 0.06 11.8 0.1 1.2 1 0 0 1 1 1 0 PhoD-like phosphatase Chlorosome_CsmC PF11098.3 EDN07619.1 - 0.11 12.2 1.5 0.21 11.3 1.1 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C WW PF00397.21 EDN07620.1 - 1.4e-08 34.3 0.3 3e-08 33.3 0.2 1.6 1 0 0 1 1 1 1 WW domain DUF4585 PF15232.1 EDN07620.1 - 0.0051 16.6 3.5 0.0055 16.5 0.0 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4585) Fungal_trans_2 PF11951.3 EDN07621.1 - 1.3e-20 73.4 4.4 1.7e-20 72.9 3.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN07621.1 - 0.00016 21.4 1.0 0.00032 20.5 0.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ecm29 PF13001.2 EDN07622.1 - 1.6e-161 538.2 0.0 1.2e-160 535.3 0.0 2.4 3 0 0 3 3 3 1 Proteasome stabiliser Ipi1_N PF12333.3 EDN07622.1 - 0.003 17.5 0.3 2.1 8.3 0.0 4.6 3 1 1 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 EDN07622.1 - 0.0042 17.5 11.1 0.64 10.5 0.1 7.3 8 1 0 8 8 8 1 HEAT-like repeat HEAT PF02985.17 EDN07622.1 - 0.019 15.0 14.0 1.7 8.9 0.0 8.9 11 0 0 11 11 11 0 HEAT repeat SNF2_N PF00176.18 EDN07623.1 - 5.1e-49 166.6 0.0 8.6e-49 165.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4 PF00097.20 EDN07623.1 - 1.4e-09 37.4 8.9 3.5e-09 36.1 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN07623.1 - 1.1e-08 34.7 10.6 2.5e-08 33.5 7.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDN07623.1 - 7e-08 32.0 6.5 1.7e-07 30.7 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN07623.1 - 2.4e-07 30.6 10.5 5.9e-07 29.4 7.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDN07623.1 - 0.0001 22.3 5.5 0.0001 22.3 3.8 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EDN07623.1 - 0.00022 20.8 8.6 0.00053 19.6 6.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain TPR_2 PF07719.12 EDN07623.1 - 0.00037 20.1 0.3 0.0012 18.5 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Helicase_C PF00271.26 EDN07623.1 - 0.00098 18.9 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 EDN07623.1 - 0.0034 17.2 8.2 0.007 16.2 5.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING TPR_14 PF13428.1 EDN07623.1 - 0.004 17.6 0.4 0.021 15.4 0.3 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat Baculo_IE-1 PF05290.6 EDN07623.1 - 0.0049 16.5 0.2 0.01 15.6 0.1 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) TPR_1 PF00515.23 EDN07623.1 - 0.0059 16.1 0.1 0.017 14.7 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDN07623.1 - 0.064 12.9 0.1 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 TPR repeat zf-RING_4 PF14570.1 EDN07623.1 - 0.19 11.3 4.9 0.72 9.4 3.4 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EDN07623.1 - 0.32 10.7 7.2 0.74 9.5 5.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 EDN07623.1 - 0.32 10.5 3.7 0.83 9.2 2.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.2 EDN07623.1 - 8.2 6.3 6.7 11 5.8 2.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon Pkinase PF00069.20 EDN07624.1 - 1.4e-17 63.7 0.0 2.4e-17 62.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07624.1 - 0.00025 20.1 0.0 0.00049 19.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase COesterase PF00135.23 EDN07625.1 - 5.7e-71 239.8 0.0 7.4e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EDN07625.1 - 4.4e-10 39.5 0.1 7.7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDN07625.1 - 0.00015 21.0 0.0 0.00028 20.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDN07625.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pribosyltran PF00156.22 EDN07626.1 - 1.1e-15 57.4 0.0 1.8e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PMP22_Claudin PF00822.15 EDN07626.1 - 0.11 12.1 0.1 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Tic20 PF09685.5 EDN07627.1 - 0.0029 17.5 3.1 0.0037 17.2 0.8 1.9 2 0 0 2 2 2 1 Tic20-like protein YhhN PF07947.9 EDN07627.1 - 0.02 14.2 0.1 0.21 10.9 0.1 2.3 3 0 0 3 3 3 0 YhhN-like protein DUF1469 PF07332.6 EDN07627.1 - 0.052 13.2 1.1 0.56 9.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Plasmid_RAQPRD PF09686.5 EDN07627.1 - 0.14 12.2 1.8 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Ank_2 PF12796.2 EDN07628.1 - 1e-28 99.4 10.0 1.1e-14 54.5 0.7 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EDN07628.1 - 1.5e-17 62.4 4.9 3.5e-06 26.5 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EDN07628.1 - 6.3e-14 50.7 2.2 0.00062 19.7 0.2 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EDN07628.1 - 7.5e-14 51.4 2.6 4.1e-06 26.8 0.4 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN07628.1 - 2.5e-11 43.7 0.6 0.00011 22.6 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PMM PF03332.8 EDN07629.1 - 4e-103 343.7 0.1 4.6e-103 343.5 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EDN07629.1 - 0.0013 18.3 0.0 0.0023 17.5 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EDN07629.1 - 0.016 14.3 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1640 PF07798.6 EDN07630.1 - 6.8e-63 211.8 3.6 8.1e-63 211.6 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Syntaxin PF00804.20 EDN07630.1 - 2.5 8.3 6.5 7.3 6.8 3.9 2.1 1 1 0 1 1 1 0 Syntaxin Trypsin_2 PF13365.1 EDN07631.1 - 3.2e-14 52.9 0.0 6.8e-14 51.8 0.0 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EDN07631.1 - 0.006 16.1 0.2 0.1 12.1 0.1 2.5 1 1 0 1 1 1 1 Trypsin Peptidase_C4 PF00863.14 EDN07631.1 - 0.015 14.2 0.0 0.074 12.0 0.0 1.9 2 0 0 2 2 2 0 Peptidase family C4 PNGaseA PF12222.3 EDN07632.1 - 9.3e-85 285.0 0.8 6.9e-81 272.3 0.0 2.2 1 1 1 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Fungal_trans PF04082.13 EDN07633.1 - 1.8e-22 79.4 0.7 2.9e-22 78.7 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN07633.1 - 1e-07 31.7 8.0 1.9e-07 30.8 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EDN07634.1 - 0.00029 19.6 40.8 0.00072 18.3 25.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DAP PF15228.1 EDN07635.1 - 0.068 13.9 0.1 0.082 13.6 0.1 1.1 1 0 0 1 1 1 0 Death-associated protein DnaJ PF00226.26 EDN07636.1 - 1.2e-17 63.3 0.2 2.5e-17 62.3 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Bacteriocin_IIc PF10439.4 EDN07636.1 - 0.2 11.8 5.3 0.41 10.7 3.7 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.1 EDN07636.1 - 2 8.0 13.7 0.16 11.6 6.2 1.6 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DnaJ PF00226.26 EDN07637.1 - 3.7e-11 42.6 0.1 7.4e-11 41.6 0.1 1.5 1 1 0 1 1 1 1 DnaJ domain PRA1 PF03208.14 EDN07638.1 - 1.5e-26 92.5 0.2 2.2e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 PRA1 family protein Frag1 PF10277.4 EDN07640.1 - 2.2e-22 79.6 6.4 1.4e-14 54.0 0.1 2.0 1 1 1 2 2 2 2 Frag1/DRAM/Sfk1 family DUF1109 PF06532.6 EDN07640.1 - 0.013 14.8 3.3 0.077 12.4 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1109) SUR7 PF06687.7 EDN07640.1 - 0.91 9.0 4.6 0.69 9.4 2.2 1.5 2 0 0 2 2 2 0 SUR7/PalI family Y_phosphatase3 PF13350.1 EDN07641.1 - 4.7e-17 62.7 0.0 1.6e-12 48.0 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EDN07641.1 - 3.9e-06 26.8 0.1 9.4e-06 25.6 0.1 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EDN07641.1 - 5.4e-06 25.8 0.0 8.8e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EDN07641.1 - 0.027 13.8 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 EDN07641.1 - 0.17 11.4 0.0 0.45 10.0 0.0 1.6 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain SpoIISB_antitox PF14185.1 EDN07642.1 - 0.09 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Antitoxin SpoIISB, type II toxin-antitoxin system DUF3812 PF12757.2 EDN07644.1 - 3.9e-25 88.2 18.6 1.1e-24 86.8 7.1 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3812) Acetyltransf_3 PF13302.1 EDN07645.1 - 3.8e-13 49.8 0.0 5.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EDN07645.1 - 2.3e-07 30.8 0.0 3.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN07645.1 - 0.0019 18.1 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AAA_17 PF13207.1 EDN07646.1 - 0.0024 18.6 0.0 0.0086 16.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDN07646.1 - 0.013 15.8 0.0 0.09 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EDN07646.1 - 0.032 14.1 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EDN07646.1 - 0.067 13.1 0.0 0.45 10.4 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain MFS_1 PF07690.11 EDN07647.1 - 4.3e-29 101.3 50.8 2.2e-21 75.9 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.6 EDN07647.1 - 0.15 11.3 7.4 0.052 12.8 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) MFS_1_like PF12832.2 EDN07647.1 - 0.19 11.5 6.9 0.29 10.9 0.3 3.4 4 0 0 4 4 4 0 MFS_1 like family Yae1_N PF09811.4 EDN07648.1 - 5.4e-05 22.6 16.1 0.64 9.5 11.2 2.8 1 1 0 1 1 1 1 Essential protein Yae1, N terminal Romo1 PF10247.4 EDN07648.1 - 0.05 13.7 22.9 1.5e+04 -5.0 15.9 3.2 1 1 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_Omp PF13488.1 EDN07648.1 - 0.32 10.6 24.2 29 4.3 16.8 2.2 1 1 0 1 1 1 0 Glycine zipper DUF2798 PF11391.3 EDN07648.1 - 1.4 8.7 16.7 3.8e+02 0.9 11.6 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2798) FUN14 PF04930.10 EDN07648.1 - 3.2 8.0 22.9 0.89 9.8 0.1 3.8 1 1 1 2 2 2 0 FUN14 family Abhydrolase_9_N PF15420.1 EDN07648.1 - 7 6.3 9.9 2.9e+02 1.0 6.8 2.4 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Gly-zipper_OmpA PF13436.1 EDN07648.1 - 9.5 5.9 14.3 36 4.0 9.9 1.8 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF1440 PF07274.7 EDN07648.1 - 9.7 6.1 7.1 56 3.7 4.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1440) Pkinase PF00069.20 EDN07650.1 - 4.8e-59 199.6 0.1 4.7e-58 196.3 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07650.1 - 5e-37 127.3 0.0 3.1e-36 124.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN07650.1 - 2.4e-09 36.5 0.0 2.4e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDN07650.1 - 0.0019 17.9 0.9 0.52 9.9 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EDN07650.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prenyltrans PF00432.16 EDN07651.1 - 2.9e-29 100.2 10.2 4.2e-06 26.2 0.1 6.5 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EDN07651.1 - 6.2e-21 74.9 0.0 3e-16 59.8 0.0 3.6 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EDN07651.1 - 1.6e-06 28.0 0.0 0.002 18.1 0.0 3.4 2 1 2 4 4 4 3 Prenyltransferase-like DDE_1 PF03184.14 EDN07652.1 - 7.4e-37 126.5 0.0 1.4e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN07652.1 - 3.9e-11 42.5 0.8 8.7e-10 38.2 0.0 3.1 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain PFL PF02901.10 EDN07652.1 - 0.0078 14.6 0.7 0.013 13.9 0.5 1.3 1 0 0 1 1 1 1 Pyruvate formate lyase DDE_Tnp_1_7 PF13843.1 EDN07653.1 - 5.4e-30 104.6 0.7 1.6e-14 53.7 0.0 3.1 2 1 1 3 3 3 3 Transposase IS4 COX7C PF02935.11 EDN07654.1 - 0.44 10.3 3.5 1.5 8.6 2.4 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIc MFS_1 PF07690.11 EDN07655.1 - 1.1e-30 106.5 13.0 1.1e-30 106.5 9.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN07655.1 - 0.0003 19.4 11.9 0.0003 19.4 8.3 3.8 3 3 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EDN07657.1 - 5.4e-09 35.2 31.8 9e-09 34.4 22.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EDN07657.1 - 1.7e-05 24.3 6.3 1.7e-05 24.3 4.4 3.2 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF1049 PF06305.6 EDN07657.1 - 0.44 10.0 0.0 0.44 10.0 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1049) PsbX PF06596.6 EDN07657.1 - 4 7.1 8.2 0.89 9.2 0.8 2.8 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) CBM_5_12 PF02839.9 EDN07659.1 - 4.7e-06 26.0 0.5 4.7e-06 26.0 0.3 2.3 2 0 0 2 2 2 1 Carbohydrate binding domain Striatin PF08232.7 EDN07659.1 - 2.4 8.4 8.9 2.6 8.3 4.3 2.3 2 0 0 2 2 2 0 Striatin family PT-TG PF14449.1 EDN07660.1 - 0.00011 21.9 0.0 0.00036 20.2 0.0 1.9 1 0 0 1 1 1 1 Pre-toxin TG Imm45 PF15603.1 EDN07660.1 - 0.26 11.4 1.4 2.6 8.2 0.0 2.8 3 0 0 3 3 3 0 Immunity protein 45 Ribosomal_L7Ae PF01248.21 EDN07661.1 - 7.1e-26 89.5 0.0 8.3e-26 89.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EDN07661.1 - 9.2e-05 22.3 0.1 0.00011 22.1 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EDN07661.1 - 0.008 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain E1-E2_ATPase PF00122.15 EDN07662.1 - 2.3e-64 216.6 8.9 1.9e-63 213.5 5.6 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDN07662.1 - 3.4e-46 157.0 5.4 3.4e-46 157.0 3.7 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDN07662.1 - 7.8e-34 117.9 0.0 6.9e-33 114.8 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN07662.1 - 3.3e-20 71.8 0.0 6.6e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EDN07662.1 - 1e-16 61.6 0.0 4.7e-16 59.5 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDN07662.1 - 4.4e-16 58.1 0.0 1.4e-15 56.4 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EDN07662.1 - 1.2e-08 34.8 1.4 2.1e-06 27.5 0.8 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EDN07662.1 - 0.0087 16.3 0.0 0.023 14.9 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase 14-3-3 PF00244.15 EDN07663.1 - 5e-102 339.9 0.1 6.7e-102 339.5 0.1 1.1 1 0 0 1 1 1 1 14-3-3 protein Ribosomal_60s PF00428.14 EDN07663.1 - 0.46 10.9 12.2 0.77 10.1 5.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_S32 PF05579.8 EDN07664.1 - 0.00064 18.7 0.0 0.0007 18.6 0.0 1.1 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.4 EDN07664.1 - 0.066 11.6 0.1 0.086 11.2 0.0 1.1 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S7 PF00949.16 EDN07664.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease eIF3_subunit PF08597.5 EDN07665.1 - 1.7e-70 237.4 24.6 1.9e-70 237.2 17.1 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit BTV_NS2 PF04514.7 EDN07665.1 - 0.0027 16.6 11.1 0.0043 16.0 7.7 1.3 1 0 0 1 1 1 1 Bluetongue virus non-structural protein NS2 Nucleo_P87 PF07267.6 EDN07665.1 - 0.34 9.5 14.9 0.56 8.8 10.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ycf1 PF05758.7 EDN07665.1 - 1.2 6.7 6.6 1.2 6.7 4.5 1.2 1 0 0 1 1 1 0 Ycf1 Plasmodium_Vir PF05795.6 EDN07665.1 - 2.3 7.3 6.0 0.4 9.8 1.6 1.6 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF3827 PF12877.2 EDN07665.1 - 3.5 5.5 9.9 0.39 8.7 4.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) TFIIF_alpha PF05793.7 EDN07665.1 - 3.7 5.7 27.3 0.082 11.2 12.6 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3408 PF11888.3 EDN07666.1 - 0.012 15.4 1.8 0.015 15.2 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DDE_1 PF03184.14 EDN07669.1 - 5.5e-34 117.2 0.0 4.5e-33 114.2 0.0 2.2 1 1 1 2 2 2 1 DDE superfamily endonuclease HNH_2 PF13391.1 EDN07669.1 - 2e-09 37.0 0.0 4.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease HTH_Tnp_Tc5 PF03221.11 EDN07669.1 - 2.2e-05 24.1 0.0 7.9e-05 22.3 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Enolase_N PF03952.11 EDN07670.1 - 2e-15 56.8 0.3 3.2e-15 56.2 0.2 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain DDE_Tnp_1_7 PF13843.1 EDN07670.1 - 0.0073 15.3 0.0 0.0098 14.9 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 AAA PF00004.24 EDN07671.1 - 5.2e-43 146.3 0.0 8.8e-43 145.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN07671.1 - 1.2e-07 31.8 0.0 2.5e-06 27.5 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EDN07671.1 - 1.5e-06 27.9 0.1 3.7e-05 23.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDN07671.1 - 2.5e-06 27.5 0.0 7.7e-06 25.9 0.0 1.9 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EDN07671.1 - 2.9e-06 27.4 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EDN07671.1 - 7.4e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EDN07671.1 - 0.00021 20.3 0.0 0.00058 18.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EDN07671.1 - 0.00034 20.2 0.0 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EDN07671.1 - 0.00071 20.3 0.5 0.0028 18.4 0.1 2.2 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EDN07671.1 - 0.0012 18.7 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDN07671.1 - 0.0017 18.2 0.0 0.0063 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EDN07671.1 - 0.0018 17.0 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 EDN07671.1 - 0.0028 17.9 0.1 0.0081 16.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EDN07671.1 - 0.0028 17.1 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EDN07671.1 - 0.0031 16.7 0.0 0.0062 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EDN07671.1 - 0.005 17.0 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EDN07671.1 - 0.0058 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EDN07671.1 - 0.0075 15.7 0.0 0.027 13.9 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EDN07671.1 - 0.0089 15.4 0.1 0.047 13.0 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 EDN07671.1 - 0.0094 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EDN07671.1 - 0.01 15.4 0.3 0.26 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF4200 PF13863.1 EDN07671.1 - 0.013 15.4 1.3 0.032 14.1 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AAA_23 PF13476.1 EDN07671.1 - 0.015 15.6 1.8 3.5 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EDN07671.1 - 0.018 14.8 0.0 0.062 13.1 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 EDN07671.1 - 0.018 14.6 0.1 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EDN07671.1 - 0.022 14.4 0.1 0.13 11.8 0.0 2.3 2 1 0 2 2 2 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EDN07671.1 - 0.023 14.7 0.0 0.065 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EDN07671.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EDN07671.1 - 0.029 13.4 0.3 0.11 11.5 0.0 2.1 3 0 0 3 3 2 0 KaiC PhoH PF02562.11 EDN07671.1 - 0.031 13.4 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EDN07671.1 - 0.041 13.5 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EDN07671.1 - 0.051 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EDN07671.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EDN07671.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IncA PF04156.9 EDN07671.1 - 1.4 8.4 3.9 2.7 7.5 2.7 1.4 1 0 0 1 1 1 0 IncA protein Glyco_hydro_47 PF01532.15 EDN07672.1 - 4.2e-163 543.1 0.0 5.1e-163 542.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 EDN07672.1 - 0.00036 19.9 0.1 0.00076 18.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Peptidase_M20 PF01546.23 EDN07673.1 - 2.6e-19 69.4 0.1 3.8e-19 68.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EDN07673.1 - 1.7e-18 66.4 0.0 3.7e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 EDN07673.1 - 0.048 12.4 0.0 0.6 8.8 0.0 2.1 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase HATPase_c PF02518.21 EDN07674.1 - 4.9e-19 68.0 0.0 9.2e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EDN07674.1 - 7.7e-16 58.0 0.5 7.4e-09 35.6 0.1 3.3 2 1 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EDN07674.1 - 2.8e-06 27.1 0.6 9.9e-06 25.4 0.0 2.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EDN07674.1 - 0.031 13.9 0.0 0.092 12.4 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MSA-2c PF12238.3 EDN07674.1 - 4.7 6.8 4.7 12 5.4 3.2 1.7 1 0 0 1 1 1 0 Merozoite surface antigen 2c Ribosomal_L36e PF01158.13 EDN07675.1 - 5.8e-40 135.2 8.1 6.6e-40 135.0 5.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EDN07675.1 - 0.0021 17.2 0.1 0.0023 17.0 0.1 1.0 1 0 0 1 1 1 1 LemA family MRP-L28 PF09812.4 EDN07675.1 - 0.092 12.5 1.2 0.11 12.3 0.8 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 TUG-UBL1 PF11470.3 EDN07676.1 - 1.2e-25 89.1 0.1 2.7e-25 88.0 0.1 1.6 1 0 0 1 1 1 1 GLUT4 regulating protein TUG FERM_N PF09379.5 EDN07676.1 - 0.02 14.9 0.0 0.55 10.3 0.0 2.5 2 1 0 2 2 2 0 FERM N-terminal domain RBD PF02196.10 EDN07676.1 - 0.023 14.4 0.1 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain Rad60-SLD PF11976.3 EDN07676.1 - 0.033 13.8 0.0 0.077 12.6 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF605 PF04652.11 EDN07676.1 - 1.4 8.2 20.2 2.1 7.6 14.0 1.2 1 0 0 1 1 1 0 Vta1 like Hemerythrin PF01814.18 EDN07677.1 - 8.4e-14 51.8 0.6 1.2e-13 51.3 0.4 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DEC-1_C PF04626.8 EDN07678.1 - 0.12 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Dec-1 protein, C terminal region Pkinase PF00069.20 EDN07679.1 - 4.2e-10 39.2 0.0 5.4e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07679.1 - 3.3e-05 23.0 0.0 4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Proteasome PF00227.21 EDN07680.1 - 3.5e-36 124.2 0.0 4e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit NatB_MDM20 PF09797.4 EDN07681.1 - 2.6e-102 342.2 0.8 3.8e-102 341.7 0.6 1.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 EDN07681.1 - 8.6e-06 26.0 5.7 0.051 13.9 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN07681.1 - 0.44 11.2 7.6 5.6 7.7 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3647 PF12363.3 EDN07683.1 - 0.22 11.6 3.9 0.7 10.0 0.2 2.9 3 0 0 3 3 3 0 Phage protein AAA PF00004.24 EDN07684.1 - 9.8e-18 64.6 0.0 2.2e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN07684.1 - 2.7e-05 24.2 0.2 0.00019 21.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDN07684.1 - 0.00019 21.5 0.1 0.00079 19.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDN07684.1 - 0.0031 17.4 0.0 0.37 10.6 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDN07684.1 - 0.0093 15.6 0.0 0.03 14.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EDN07684.1 - 0.01 16.6 0.1 0.058 14.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDN07684.1 - 0.019 14.6 2.6 0.077 12.7 0.7 2.5 2 1 0 2 2 2 0 Part of AAA domain CPT PF07931.7 EDN07684.1 - 0.033 13.8 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RuvB_N PF05496.7 EDN07684.1 - 0.05 12.6 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EDN07684.1 - 0.089 12.6 0.3 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain CHCH PF06747.8 EDN07685.1 - 0.00036 20.3 5.5 0.00072 19.4 3.8 1.6 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 EDN07685.1 - 0.0012 19.0 3.3 0.0018 18.3 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) zinc_ribbon_2 PF13240.1 EDN07686.1 - 0.038 13.4 1.3 0.11 12.0 0.9 1.9 1 0 0 1 1 1 0 zinc-ribbon domain WD40 PF00400.27 EDN07687.1 - 1.2e-24 85.2 18.6 1.8e-06 27.5 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EDN07687.1 - 0.017 13.9 1.6 0.66 8.6 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like Proteasome PF00227.21 EDN07688.1 - 1.8e-37 128.5 0.0 2e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit UCH PF00443.24 EDN07689.1 - 3.9e-22 78.6 0.0 1.1e-21 77.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EDN07689.1 - 1.2e-11 44.4 0.2 3.1e-11 43.2 0.1 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EDN07689.1 - 0.0055 16.1 0.0 0.0082 15.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EDN07692.1 - 2e-76 249.3 32.0 1.6e-08 34.0 0.4 12.1 11 1 0 11 11 11 11 WD domain, G-beta repeat Utp13 PF08625.6 EDN07692.1 - 2.3e-47 160.1 0.1 3.6e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EDN07692.1 - 3.7e-10 38.5 6.3 0.0065 14.6 0.1 5.1 3 1 1 5 5 5 4 Nucleoporin Nup120/160 DUF3312 PF11768.3 EDN07692.1 - 0.21 9.7 0.0 1.6 6.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) G-patch_2 PF12656.2 EDN07693.1 - 3.9e-28 97.1 0.1 1.4e-27 95.3 0.0 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site G-patch PF01585.18 EDN07693.1 - 0.019 14.7 0.3 0.019 14.7 0.2 1.9 2 0 0 2 2 2 0 G-patch domain HSA PF07529.8 EDN07694.1 - 7.6e-24 83.3 0.7 7.6e-24 83.3 0.5 4.5 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 EDN07694.1 - 2.3e-13 50.0 0.1 5e-12 45.7 0.1 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain WD40 PF00400.27 EDN07695.1 - 1.9e-09 37.0 0.0 0.62 10.0 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat GTP_EFTU PF00009.22 EDN07696.1 - 7.5e-38 129.8 0.5 1.2e-37 129.1 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EDN07696.1 - 1.1e-36 124.6 0.1 2.2e-36 123.7 0.1 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EDN07696.1 - 1.1e-11 44.6 0.2 2.6e-11 43.4 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDN07696.1 - 0.0034 17.3 0.0 0.0075 16.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDN07696.1 - 0.067 13.0 0.2 0.28 11.0 0.1 2.1 2 1 0 2 2 2 0 Dynamin family RNA_polI_A14 PF08203.6 EDN07699.1 - 0.0087 16.2 0.0 0.026 14.7 0.0 1.7 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 DUF4519 PF15012.1 EDN07699.1 - 6.2 6.8 8.8 11 6.0 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Peptidase_M48 PF01435.13 EDN07700.1 - 4.2e-52 176.9 0.0 6.4e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EDN07700.1 - 0.0094 14.9 0.1 0.031 13.2 0.0 1.9 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF4538 PF15061.1 EDN07700.1 - 0.087 12.1 3.8 0.05 12.9 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) DUF2201_N PF13203.1 EDN07700.1 - 0.23 10.6 0.1 0.41 9.7 0.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF955 PF06114.8 EDN07700.1 - 0.26 11.0 2.4 0.6 9.8 1.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF955) Peptidase_M16_C PF05193.16 EDN07701.1 - 8.2e-20 71.2 0.0 8.3e-16 58.1 0.0 3.6 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EDN07701.1 - 5.7e-06 26.1 0.7 2.8e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Racemase_4 PF13615.1 EDN07701.1 - 0.069 13.3 0.0 0.24 11.6 0.0 1.9 1 0 0 1 1 1 0 Putative alanine racemase M16C_assoc PF08367.6 EDN07701.1 - 1.2 7.8 4.4 3.6 6.3 1.1 2.4 2 1 0 2 2 2 0 Peptidase M16C associated Zw10 PF06248.8 EDN07702.1 - 1.5e-11 43.2 3.3 6.2e-05 21.3 0.6 3.2 2 1 1 3 3 3 3 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EDN07702.1 - 3.4e-05 23.1 1.5 6.2e-05 22.2 0.0 2.2 3 0 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal Syntaxin-6_N PF09177.6 EDN07702.1 - 0.00038 20.7 6.3 0.016 15.6 0.0 3.2 2 1 0 2 2 2 2 Syntaxin 6, N-terminal LUC7 PF03194.10 EDN07702.1 - 0.63 9.5 7.9 27 4.1 0.0 2.6 2 1 0 2 2 2 0 LUC7 N_terminus NPV_P10 PF05531.7 EDN07702.1 - 1.5 9.0 5.5 20 5.5 0.1 4.1 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein WD40 PF00400.27 EDN07703.1 - 1.1e-29 101.2 21.3 4e-08 32.8 0.4 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 EDN07703.1 - 9.3e-21 73.6 0.0 1.8e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Ribosomal_S13 PF00416.17 EDN07704.1 - 7.7e-15 55.2 0.5 8.8e-15 55.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.16 EDN07705.1 - 1.2e-46 158.7 0.9 1.4e-46 158.4 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD APH PF01636.18 EDN07706.1 - 3.3e-08 33.5 0.4 4.6e-06 26.5 0.4 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Scm3 PF10384.4 EDN07706.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Centromere protein Scm3 APH PF01636.18 EDN07707.1 - 3.5e-12 46.5 0.0 4.9e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans_2 PF11951.3 EDN07709.1 - 0.005 15.4 0.5 0.018 13.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain NmrA PF05368.8 EDN07710.1 - 7.3e-17 61.3 0.0 1.3e-16 60.5 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN07710.1 - 3.8e-07 30.3 0.0 7.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding DUF1635 PF07795.6 EDN07710.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DEAD PF00270.24 EDN07711.1 - 3.9e-47 159.8 0.0 4.8e-46 156.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN07711.1 - 2.8e-27 94.3 0.0 6.5e-27 93.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EDN07711.1 - 0.0082 14.6 0.0 0.068 11.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1253) ResIII PF04851.10 EDN07711.1 - 0.041 13.7 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit INSIG PF07281.7 EDN07713.1 - 5.4e-46 156.3 0.9 6.3e-46 156.1 0.7 1.0 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) AICARFT_IMPCHas PF01808.13 EDN07714.1 - 6e-107 357.3 0.0 9.1e-107 356.7 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EDN07714.1 - 1.7e-25 88.7 0.0 3.1e-25 87.9 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Clathrin PF00637.15 EDN07715.1 - 3.8e-197 645.7 43.1 6.8e-36 123.0 0.9 7.3 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EDN07715.1 - 9.7e-25 86.2 0.3 4.2e-24 84.2 0.0 2.4 2 0 0 2 2 1 1 Clathrin-H-link Clathrin-link PF09268.5 EDN07715.1 - 4.8e-11 41.4 0.1 1.1e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Clathrin_propel PF01394.15 EDN07715.1 - 2e-07 30.8 0.2 23 5.5 0.0 6.7 7 0 0 7 7 7 0 Clathrin propeller repeat TPR_7 PF13176.1 EDN07715.1 - 0.00031 20.3 3.2 58 3.8 0.0 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Vps39_1 PF10366.4 EDN07715.1 - 0.00056 19.8 3.2 1.8 8.6 0.0 4.9 3 1 1 4 4 4 1 Vacuolar sorting protein 39 domain 1 TPR_12 PF13424.1 EDN07715.1 - 0.0081 16.0 1.6 3.5 7.6 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF2191 PF09957.4 EDN07715.1 - 0.017 14.8 0.2 0.082 12.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2191) Ank_3 PF13606.1 EDN07715.1 - 0.086 13.1 0.0 1.1 9.7 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat TPR_14 PF13428.1 EDN07715.1 - 0.4 11.4 14.0 11 6.9 0.1 7.3 10 0 0 10 10 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDN07715.1 - 0.51 10.7 5.5 37 4.7 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DIM1 PF02966.11 EDN07716.1 - 9.6e-68 225.8 0.2 1.1e-67 225.5 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EDN07716.1 - 0.0022 18.0 0.4 0.004 17.2 0.3 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 EDN07716.1 - 0.0055 16.3 0.0 0.007 16.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EDN07716.1 - 0.062 13.3 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like CPSase_L_D2 PF02786.12 EDN07717.1 - 7.8e-80 267.1 0.1 1.2e-79 266.5 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EDN07717.1 - 2.1e-66 223.0 0.0 3.7e-66 222.3 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EDN07717.1 - 7.5e-36 122.5 0.0 1.5e-35 121.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EDN07717.1 - 1.2e-28 99.2 0.0 2.7e-28 98.0 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EDN07717.1 - 2.3e-26 92.8 0.0 3.9e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EDN07717.1 - 2.7e-18 66.3 0.1 5.3e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EDN07717.1 - 5e-15 55.0 0.0 2.3e-14 52.9 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EDN07717.1 - 9.3e-11 41.4 0.0 1.8e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EDN07717.1 - 7.5e-08 31.9 0.0 1.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EDN07717.1 - 2.1e-06 27.3 0.0 5.5e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Biotin_lipoyl PF00364.17 EDN07717.1 - 1.3e-05 24.6 1.7 0.00066 19.2 0.1 3.0 2 1 1 3 3 3 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.9 EDN07717.1 - 0.00011 22.1 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EDN07717.1 - 0.0015 18.1 1.5 1.1 8.9 0.0 3.2 3 0 0 3 3 3 2 Biotin-lipoyl like GARS_A PF01071.14 EDN07717.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Beta-lactamase PF00144.19 EDN07718.1 - 1.2e-61 208.6 0.1 1.4e-61 208.3 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase Ribosomal_L5_C PF00673.16 EDN07721.1 - 1.5e-22 79.1 0.0 2.4e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EDN07721.1 - 4.2e-21 74.4 0.0 1e-20 73.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 EDN07722.1 - 5.1e-17 61.1 0.0 7e-17 60.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.8 EDN07723.1 - 2.1e-20 72.8 1.9 1.1e-15 57.5 0.3 2.1 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0041) Aa_trans PF01490.13 EDN07724.1 - 3.3e-59 200.4 22.1 1e-37 129.6 3.4 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein AA_permease PF00324.16 EDN07725.1 - 2.1e-24 85.7 32.4 7.8e-17 60.7 16.6 2.2 1 1 1 2 2 2 2 Amino acid permease Sugar_tr PF00083.19 EDN07726.1 - 2.1e-106 356.2 13.1 2.8e-106 355.8 9.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN07726.1 - 5.8e-17 61.4 9.9 5.8e-17 61.4 6.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EDN07726.1 - 0.00063 17.9 2.9 0.0013 16.8 1.6 1.9 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.13 EDN07729.1 - 7.4e-06 25.7 8.7 1.4e-05 24.8 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GHMP_kinases_N PF00288.21 EDN07730.1 - 1.8e-19 69.5 0.1 4.4e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EDN07730.1 - 1e-07 32.0 0.0 2.8e-07 30.6 0.0 1.8 1 1 0 1 1 1 1 GHMP kinases C terminal PPTA PF01239.17 EDN07731.1 - 3e-33 111.7 15.1 1.7e-08 33.4 0.9 5.8 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Nucleoplasmin PF03066.10 EDN07731.1 - 0.053 13.0 10.9 0.55 9.7 3.4 2.3 2 0 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 EDN07731.1 - 0.081 12.5 9.0 0.84 9.2 2.8 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region PBP1_TM PF14812.1 EDN07731.1 - 2.5 8.4 14.1 4.3 7.7 1.4 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SPT6_acidic PF14632.1 EDN07731.1 - 6.5 6.9 22.7 3.2 7.9 5.8 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 PALP PF00291.20 EDN07732.1 - 1.4e-44 152.5 4.9 1.4e-44 152.5 3.4 2.9 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Anticodon_1 PF08264.8 EDN07733.1 - 1.4e-05 24.8 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EDN07733.1 - 0.00084 18.1 0.0 0.002 16.8 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1g PF09334.6 EDN07734.1 - 8.8e-73 245.2 0.0 1.5e-72 244.3 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EDN07734.1 - 2.4e-10 39.0 0.0 1.4e-08 33.2 0.0 2.7 2 1 1 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EDN07734.1 - 0.017 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain NTF2 PF02136.15 EDN07735.1 - 1.7e-08 34.8 0.1 5.8e-08 33.1 0.1 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Chorion_2 PF03964.10 EDN07735.1 - 0.0087 16.5 4.0 1.1 9.8 0.6 2.2 2 0 0 2 2 2 2 Chorion family 2 Mtr2 PF10429.4 EDN07735.1 - 0.012 15.4 0.0 0.03 14.0 0.0 1.6 2 0 0 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 Ribosomal_60s PF00428.14 EDN07735.1 - 0.032 14.6 3.8 0.032 14.6 2.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glucodextran_B PF09136.5 EDN07735.1 - 0.091 12.9 2.8 0.16 12.1 1.9 1.3 1 0 0 1 1 1 0 Glucodextranase, domain B Ribosomal_L38e PF01781.13 EDN07736.1 - 1.7e-32 110.9 2.7 2e-32 110.7 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family CLTH PF10607.4 EDN07736.1 - 0.069 12.8 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Acetyltransf_3 PF13302.1 EDN07737.1 - 2.8e-24 85.9 0.0 4.6e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EDN07737.1 - 0.019 14.8 0.0 0.87 9.4 0.0 2.6 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDN07737.1 - 0.021 14.5 0.8 2.2 8.0 0.0 2.8 3 0 0 3 3 3 0 FR47-like protein SR-25 PF10500.4 EDN07737.1 - 4.2 6.7 5.7 7.7 5.9 4.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DNA_pol_E_B PF04042.11 EDN07738.1 - 9.2e-49 165.5 0.0 1.3e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PLDc_2 PF13091.1 EDN07739.1 - 2.9e-18 65.8 0.0 2.5e-11 43.3 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EDN07739.1 - 0.061 13.1 1.5 2.9 7.8 0.0 3.0 2 1 0 2 2 2 0 Phospholipase D Active site motif NMO PF03060.10 EDN07740.1 - 4.9e-54 183.6 2.3 6.2e-54 183.3 1.6 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EDN07740.1 - 0.00082 18.3 1.3 0.0012 17.7 0.9 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EDN07740.1 - 0.0049 15.8 1.5 0.0049 15.8 1.1 1.9 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Taxilin PF09728.4 EDN07741.1 - 3.9e-100 334.9 48.8 3.9e-100 334.9 33.8 1.4 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DUF812 PF05667.6 EDN07741.1 - 0.013 14.0 41.3 0.062 11.8 10.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF3584 PF12128.3 EDN07741.1 - 0.1 9.9 49.1 0.032 11.5 31.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4201 PF13870.1 EDN07741.1 - 0.98 8.8 56.5 0.12 11.8 13.4 4.8 2 2 2 4 4 4 0 Domain of unknown function (DUF4201) IncA PF04156.9 EDN07741.1 - 2.8 7.5 51.0 1.6 8.3 9.1 4.0 1 1 2 3 3 3 0 IncA protein DUF725 PF05267.7 EDN07741.1 - 3 7.7 8.4 0.2 11.5 1.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF725) DUF3675 PF12428.3 EDN07741.1 - 3.7 7.8 6.0 11 6.2 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) TMF_TATA_bd PF12325.3 EDN07741.1 - 7.2 6.3 51.7 0.4 10.4 7.6 4.4 2 2 3 5 5 5 0 TATA element modulatory factor 1 TATA binding M16C_assoc PF08367.6 EDN07742.1 - 2e-57 193.9 0.7 3e-57 193.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EDN07742.1 - 5.4e-23 81.6 0.0 1.5e-11 44.3 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EDN07742.1 - 2e-10 40.6 0.0 2.2e-09 37.2 0.0 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DivIC PF04977.10 EDN07742.1 - 0.066 12.7 0.5 2.3 7.7 0.0 2.8 2 0 0 2 2 2 0 Septum formation initiator Methyltransf_11 PF08241.7 EDN07743.1 - 9.1e-16 58.1 0.0 1.8e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN07743.1 - 3.9e-15 55.9 0.0 5.3e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN07743.1 - 3.9e-15 55.7 0.0 5.2e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN07743.1 - 1.8e-14 53.9 0.0 3.2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN07743.1 - 1.1e-11 45.3 0.0 1.7e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN07743.1 - 1.3e-08 34.8 0.0 2.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN07743.1 - 1.6e-08 34.8 0.0 3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN07743.1 - 8.2e-08 31.8 0.0 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 EDN07743.1 - 6.3e-07 28.9 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 EDN07743.1 - 7e-06 25.3 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 EDN07743.1 - 2.7e-05 23.3 0.0 6.9e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 EDN07743.1 - 3.4e-05 22.7 0.0 8.5e-05 21.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 EDN07743.1 - 8e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EDN07743.1 - 8.3e-05 21.7 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.7 EDN07743.1 - 0.00031 19.6 0.0 0.00046 19.1 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.8 EDN07743.1 - 0.00039 19.6 0.0 0.00052 19.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.6 EDN07743.1 - 0.0051 16.2 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) FtsJ PF01728.14 EDN07743.1 - 0.0076 16.2 0.0 0.03 14.3 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.7 EDN07743.1 - 0.033 13.5 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EDN07743.1 - 0.042 13.5 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF202 PF02656.10 EDN07744.1 - 4.4e-15 55.6 0.1 4.4e-15 55.6 0.1 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF202) APH PF01636.18 EDN07745.1 - 6.1e-10 39.2 0.0 1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Cation_efflux PF01545.16 EDN07747.1 - 5.5e-79 265.1 0.0 1.1e-78 264.2 0.0 1.4 1 1 0 1 1 1 1 Cation efflux family S1-like PF14444.1 EDN07748.1 - 0.0095 15.6 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 S1-like Metallophos PF00149.23 EDN07749.1 - 3.2e-09 36.4 0.1 1.2e-06 28.1 0.0 2.8 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase 4HBT_2 PF13279.1 EDN07750.1 - 6.5e-07 29.8 0.1 8.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EDN07750.1 - 0.022 14.9 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily Tyrosinase PF00264.15 EDN07752.1 - 7.9e-53 179.8 1.3 9.5e-53 179.6 0.1 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase Fungal_trans PF04082.13 EDN07753.1 - 3.3e-18 65.5 0.0 5.3e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S8e PF01201.17 EDN07754.1 - 2e-35 121.8 3.0 8e-35 119.8 2.1 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e DUF2486 PF10667.4 EDN07754.1 - 0.075 13.5 1.3 0.1 13.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Ribosomal_L21p PF00829.16 EDN07755.1 - 0.037 14.1 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein DUF822 PF05687.8 EDN07755.1 - 8.1 6.7 7.5 2.8 8.3 1.1 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) Pkinase PF00069.20 EDN07756.1 - 5.9e-47 160.0 0.0 7.6e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07756.1 - 9.4e-18 64.2 0.0 1.4e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EDN07756.1 - 0.00023 20.5 0.7 0.00043 19.6 0.1 1.7 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.1 EDN07756.1 - 0.0019 17.2 0.0 0.0026 16.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN07756.1 - 0.063 12.9 0.1 3.6 7.2 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EDN07756.1 - 0.07 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PWI PF01480.12 EDN07757.1 - 8e-29 99.5 0.0 1.3e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 PWI domain Rootletin PF15035.1 EDN07760.1 - 0.00043 20.3 3.6 0.00045 20.2 2.5 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion 5_3_exonuc PF01367.15 EDN07760.1 - 0.028 14.6 0.2 0.036 14.2 0.1 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold TMF_DNA_bd PF12329.3 EDN07760.1 - 0.21 11.4 2.6 0.23 11.3 0.5 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FAA_hydrolase PF01557.13 EDN07761.1 - 9.5e-54 182.1 0.0 1.2e-53 181.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF605 PF04652.11 EDN07762.1 - 0.13 11.6 11.0 0.19 11.0 7.6 1.3 1 0 0 1 1 1 0 Vta1 like Peptidase_S46 PF10459.4 EDN07762.1 - 1.5 7.1 5.0 2 6.6 3.4 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF3584 PF12128.3 EDN07762.1 - 2.6 5.2 10.5 0.57 7.4 5.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DEAD PF00270.24 EDN07763.1 - 2.7e-43 147.4 2.9 3.2e-43 147.1 1.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN07763.1 - 5.1e-28 96.7 0.4 2.2e-27 94.7 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN07763.1 - 0.00051 19.9 0.1 0.0013 18.5 0.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EDN07763.1 - 0.0014 18.2 0.5 0.004 16.7 0.2 1.8 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.1 EDN07763.1 - 0.006 15.6 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EDN07763.1 - 0.012 15.3 0.1 0.037 13.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EDN07763.1 - 0.017 15.2 0.1 0.063 13.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain Fanconi_A PF03511.9 EDN07763.1 - 0.08 12.7 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Fanconi anaemia group A protein Flavi_DEAD PF07652.9 EDN07763.1 - 0.11 12.2 0.2 0.63 9.7 0.2 2.3 1 1 0 1 1 1 0 Flavivirus DEAD domain Cupin_8 PF13621.1 EDN07764.1 - 3.1e-15 56.3 0.0 5.3e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EDN07764.1 - 2e-07 31.2 0.2 0.0015 18.7 0.0 2.4 2 0 0 2 2 2 2 JmjC domain, hydroxylase F-box-like PF12937.2 EDN07764.1 - 1.2e-05 24.9 0.1 2.6e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN07764.1 - 0.00015 21.3 0.0 0.00033 20.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain Ctr PF04145.10 EDN07765.1 - 7.4e-08 32.5 0.2 1.9e-07 31.1 0.2 1.8 1 1 0 1 1 1 1 Ctr copper transporter family NuA4 PF09340.5 EDN07766.1 - 4.4e-27 93.5 0.1 4.4e-27 93.5 0.1 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF4551 PF15087.1 EDN07766.1 - 1.2 7.3 6.6 1.6 6.9 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Glyco_hydro_38 PF01074.17 EDN07767.1 - 4.3e-90 301.7 0.6 4.3e-90 301.7 0.4 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EDN07767.1 - 1.3e-73 248.3 0.0 5.5e-73 246.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EDN07767.1 - 7.5e-26 90.1 0.0 1.5e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain 7TMR-DISMED2 PF07696.6 EDN07767.1 - 0.042 13.2 0.1 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 7TMR-DISM extracellular 2 OPT PF03169.10 EDN07768.1 - 2.1e-75 254.4 43.8 2.5e-75 254.1 30.4 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3671 PF12420.3 EDN07768.1 - 3.9 7.4 4.4 5.2 7.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF3328 PF11807.3 EDN07769.1 - 9e-49 166.0 7.0 5.7e-48 163.4 4.9 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Pro-kuma_activ PF09286.6 EDN07771.1 - 5e-35 120.6 0.0 8.1e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EDN07771.1 - 1.2e-08 34.4 0.1 2e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Subtilase family DUF3328 PF11807.3 EDN07772.1 - 1.3e-55 188.4 0.6 1.7e-55 188.0 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 EDN07773.1 - 1.4e-18 66.7 22.8 1.1e-14 53.9 7.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN07773.1 - 1.5e-07 30.3 11.5 2.4e-07 29.7 2.7 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter SAYSvFN PF10260.4 EDN07773.1 - 0.8 9.5 3.8 0.86 9.4 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) Pro-kuma_activ PF09286.6 EDN07774.1 - 3.6e-35 121.0 0.0 1.8e-34 118.8 0.1 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EDN07774.1 - 5.6e-10 38.8 0.0 9e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Subtilase family DOMON PF03351.12 EDN07775.1 - 0.0034 17.3 0.0 0.0078 16.1 0.0 1.6 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 EDN07775.1 - 0.031 13.8 0.9 0.078 12.5 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) RAM PF15320.1 EDN07776.1 - 3.3 8.0 12.6 0.74 10.1 5.8 2.2 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein NUDIX PF00293.23 EDN07777.1 - 1.8e-10 40.5 0.0 3.1e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain GHL12 PF14882.1 EDN07777.1 - 0.068 13.2 2.4 0.16 12.1 1.7 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 12 LETM1 PF07766.8 EDN07778.1 - 1.6e-104 348.7 0.2 2.7e-104 347.9 0.2 1.4 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EDN07778.1 - 1.2e-06 27.8 0.0 0.0026 17.2 0.0 3.3 3 0 0 3 3 3 2 SAP domain DUF2838 PF10998.3 EDN07779.1 - 1.9e-46 156.4 10.2 1.9e-46 156.4 7.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Val_tRNA-synt_C PF10458.4 EDN07779.1 - 0.36 10.9 6.5 8.3 6.5 2.9 2.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Ank_2 PF12796.2 EDN07780.1 - 1e-61 205.2 4.0 1.5e-14 54.0 0.0 6.0 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EDN07780.1 - 1.5e-47 157.0 8.2 0.00029 20.4 0.0 12.2 12 0 0 12 12 12 10 Ankyrin repeat Ank_4 PF13637.1 EDN07780.1 - 9.9e-46 153.3 3.3 1.3e-08 35.1 0.0 8.0 4 3 4 9 9 9 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN07780.1 - 6.4e-38 127.9 9.6 4.4e-07 29.9 0.2 9.0 6 3 2 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN07780.1 - 9.9e-34 112.0 4.3 0.017 15.2 0.0 11.8 12 0 0 12 12 12 9 Ankyrin repeat SMC_N PF02463.14 EDN07781.1 - 1.6e-58 197.5 0.0 8.1e-58 195.2 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDN07781.1 - 3.9e-31 107.5 0.0 1.2e-30 105.8 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EDN07781.1 - 1.4e-11 44.8 10.0 4.8e-06 26.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EDN07781.1 - 1.5e-07 30.7 0.0 3.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EDN07781.1 - 0.00014 21.2 21.7 0.1 11.7 0.1 4.7 4 1 0 5 5 5 4 Reovirus sigma C capsid protein AAA_23 PF13476.1 EDN07781.1 - 0.0006 20.1 36.9 0.0006 20.1 25.6 6.4 2 2 1 3 3 3 1 AAA domain SbcCD_C PF13558.1 EDN07781.1 - 0.0011 18.8 0.0 0.0045 16.8 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 EDN07781.1 - 1.4 9.2 0.0 1.4 9.2 0.0 6.9 4 3 0 4 4 4 0 ABC transporter Spc7 PF08317.6 EDN07781.1 - 4.6 5.7 89.6 0.071 11.7 9.7 6.5 3 2 2 6 6 6 0 Spc7 kinetochore protein DUF2997 PF11211.3 EDN07783.1 - 0.015 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) Pertussis_S2S3 PF02918.10 EDN07783.1 - 0.029 14.0 0.0 0.26 11.0 0.0 2.1 1 1 1 2 2 2 0 Pertussis toxin, subunit 2 and 3, C-terminal domain E3_binding PF02817.12 EDN07784.1 - 6.8e-07 28.8 0.0 1.7e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain WD40 PF00400.27 EDN07785.1 - 6.1e-33 111.5 6.9 5.7e-07 29.1 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EDN07785.1 - 2.6e-06 27.2 0.1 0.0097 15.6 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Peptidase_M18 PF02127.10 EDN07787.1 - 2.4e-147 490.9 0.0 3.5e-147 490.3 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DUF904 PF06005.7 EDN07788.1 - 0.0012 19.0 3.3 0.0029 17.8 2.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF904) IncA PF04156.9 EDN07788.1 - 0.0028 17.2 0.4 0.0047 16.5 0.3 1.3 1 0 0 1 1 1 1 IncA protein CALCOCO1 PF07888.6 EDN07788.1 - 0.0055 15.0 0.8 0.008 14.5 0.6 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like PROL5-SMR PF15621.1 EDN07788.1 - 0.014 15.7 4.4 1 9.8 1.7 2.8 2 1 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family DUF972 PF06156.8 EDN07788.1 - 0.053 13.8 1.8 0.13 12.6 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Pox_A_type_inc PF04508.7 EDN07788.1 - 0.079 12.7 0.2 0.34 10.8 0.2 2.2 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Cep57_CLD_2 PF14197.1 EDN07788.1 - 0.096 12.6 2.4 0.16 11.9 1.0 1.9 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Syntaxin-6_N PF09177.6 EDN07788.1 - 0.098 13.0 1.7 0.5 10.8 0.9 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Microtub_assoc PF07989.6 EDN07788.1 - 0.18 11.6 5.8 1.4 8.7 0.4 2.5 1 1 1 2 2 2 0 Microtubule associated DivIC PF04977.10 EDN07788.1 - 0.48 9.9 6.8 1 8.9 0.4 2.8 1 1 2 3 3 3 0 Septum formation initiator HSP70 PF00012.15 EDN07789.1 - 3.1e-16 58.4 1.0 2.9e-12 45.3 0.1 2.1 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EDN07789.1 - 3.2e-05 22.6 0.4 0.016 13.7 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 EDN07789.1 - 0.0054 16.5 3.6 0.48 10.2 0.4 2.8 3 0 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.13 EDN07789.1 - 0.039 13.0 0.1 0.31 10.0 0.0 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase EutA PF06277.6 EDN07789.1 - 0.043 12.4 0.3 4.4 5.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA DUF1746 PF08508.5 EDN07790.1 - 2.3e-44 150.0 2.5 3.3e-44 149.5 1.7 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Med8 PF10232.4 EDN07790.1 - 0.048 13.1 0.0 0.068 12.6 0.0 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Requiem_N PF14051.1 EDN07790.1 - 0.12 12.2 0.1 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. CLP_protease PF00574.18 EDN07791.1 - 8.3e-69 230.8 0.0 1e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Clp protease Clr5 PF14420.1 EDN07791.1 - 0.013 15.3 0.9 0.026 14.4 0.7 1.4 1 0 0 1 1 1 0 Clr5 domain Hydrolase_6 PF13344.1 EDN07793.1 - 1.3e-29 102.0 0.0 2e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDN07793.1 - 1.3e-13 51.9 0.0 1.8e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN07793.1 - 3e-12 46.0 0.0 6.1e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EDN07793.1 - 3.3e-07 30.6 0.1 0.00078 19.7 0.0 2.9 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EDN07793.1 - 0.018 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) AAA PF00004.24 EDN07794.1 - 2.8e-12 46.9 0.0 6.9e-12 45.7 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN07794.1 - 1.4e-06 28.4 0.0 7.2e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN07794.1 - 2.1e-05 24.1 0.0 4.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EDN07794.1 - 3.5e-05 23.6 0.0 5.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.1 EDN07794.1 - 6.4e-05 22.6 0.0 0.0014 18.2 0.0 2.5 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA_5 PF07728.9 EDN07794.1 - 0.00011 21.9 0.2 0.026 14.2 0.1 2.9 1 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EDN07794.1 - 0.00015 21.4 0.0 0.0009 18.8 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EDN07794.1 - 0.00024 21.1 0.1 0.0056 16.6 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EDN07794.1 - 0.00079 18.5 0.0 0.0011 18.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 EDN07794.1 - 0.0011 18.1 0.1 0.06 12.4 0.0 2.6 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EDN07794.1 - 0.0015 18.1 0.2 0.0055 16.3 0.2 1.8 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EDN07794.1 - 0.0052 16.2 0.0 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_3 PF07726.6 EDN07794.1 - 0.0079 15.8 0.0 0.11 12.0 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EDN07794.1 - 0.008 16.4 0.0 0.014 15.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.18 EDN07794.1 - 0.0082 14.9 0.0 0.075 11.8 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_25 PF13481.1 EDN07794.1 - 0.0085 15.5 0.0 0.03 13.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDN07794.1 - 0.0088 15.1 0.1 0.021 13.8 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_23 PF13476.1 EDN07794.1 - 0.011 16.1 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EDN07794.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.7 2 1 0 2 2 1 0 AAA domain AAA_17 PF13207.1 EDN07794.1 - 0.017 15.9 0.1 0.031 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EDN07794.1 - 0.018 14.5 0.2 0.16 11.4 0.1 2.2 1 1 0 1 1 1 0 AAA-like domain DEAD PF00270.24 EDN07794.1 - 0.023 14.2 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF815 PF05673.8 EDN07794.1 - 0.029 13.2 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 EDN07794.1 - 0.056 13.0 0.0 0.35 10.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EDN07794.1 - 0.057 12.6 0.0 5.7 6.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 EDN07794.1 - 0.059 13.5 0.0 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 EDN07794.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain Rep_fac_C PF08542.6 EDN07794.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Replication factor C C-terminal domain AAA_29 PF13555.1 EDN07794.1 - 0.19 11.2 0.5 0.43 10.1 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain Sec20 PF03908.8 EDN07795.1 - 0.014 15.0 0.2 0.05 13.3 0.1 1.9 1 0 0 1 1 1 0 Sec20 NdhN PF11909.3 EDN07795.1 - 0.08 12.2 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N Fmp27_WPPW PF10359.4 EDN07795.1 - 0.29 9.4 2.3 0.32 9.3 1.6 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Mnd1 PF03962.10 EDN07795.1 - 0.47 10.1 4.8 0.79 9.3 3.3 1.5 1 0 0 1 1 1 0 Mnd1 family I_LWEQ PF01608.12 EDN07795.1 - 1 9.2 7.6 0.21 11.5 0.8 2.6 2 1 1 3 3 3 0 I/LWEQ domain Pyrophosphatase PF00719.14 EDN07797.1 - 2.6e-51 173.1 0.1 3.5e-51 172.7 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF4200 PF13863.1 EDN07798.1 - 0.13 12.2 1.0 0.19 11.7 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) PCDO_beta_N PF12391.3 EDN07798.1 - 0.17 11.3 1.7 0.28 10.6 1.2 1.3 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal Cwf_Cwc_15 PF04889.7 EDN07798.1 - 0.18 11.4 3.3 0.2 11.3 2.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HTH_Tnp_Tc5 PF03221.11 EDN07799.1 - 3.6e-15 55.5 0.8 9.7e-15 54.1 0.2 1.9 1 1 1 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN07799.1 - 7.7e-07 28.5 0.1 1.6e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_1 PF01527.15 EDN07799.1 - 0.035 14.0 0.1 0.073 13.0 0.0 1.7 1 1 0 1 1 1 0 Transposase Chol_subst-bind PF09129.6 EDN07799.1 - 0.08 12.0 0.1 0.091 11.8 0.0 1.1 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding DDE_1 PF03184.14 EDN07800.1 - 1.6e-09 37.2 0.2 3.1e-09 36.3 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease UPAR_LY6 PF00021.16 EDN07800.1 - 1.4 9.3 5.1 2.4 8.6 3.5 1.3 1 0 0 1 1 1 0 u-PAR/Ly-6 domain Dus PF01207.12 EDN07802.1 - 6.6e-45 153.2 0.1 2.5e-44 151.3 0.1 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_M28 PF04389.12 EDN07803.1 - 3.6e-32 111.5 0.0 5.5e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EDN07803.1 - 9.9e-13 47.6 0.6 2.4e-12 46.3 0.0 2.0 2 1 1 3 3 3 1 PA domain Peptidase_M20 PF01546.23 EDN07803.1 - 3.1e-06 26.8 0.0 5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EDN07803.1 - 0.1 11.3 0.0 0.94 8.1 0.0 2.2 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase SNF2_N PF00176.18 EDN07804.1 - 4.1e-60 203.0 0.1 6.5e-60 202.4 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN07804.1 - 3.3e-14 52.5 0.0 1.4e-13 50.4 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN07804.1 - 1.7e-08 34.5 0.0 4.6e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDN07804.1 - 1.7e-06 27.6 0.0 4.4e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HHH_3 PF12836.2 EDN07804.1 - 0.011 15.6 0.1 0.029 14.3 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif VMA21 PF09446.5 EDN07805.1 - 1.4e-08 34.5 8.5 2.6e-08 33.6 5.9 1.4 1 1 0 1 1 1 1 VMA21-like domain Ribosomal_L35Ae PF01247.13 EDN07808.1 - 3.3e-33 113.3 0.1 3.9e-33 113.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EDN07808.1 - 0.012 15.5 0.0 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 RimM N-terminal domain 2OG-FeII_Oxy PF03171.15 EDN07809.1 - 2.3e-17 63.1 0.0 4.2e-17 62.2 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EDN07809.1 - 0.01 16.3 0.1 0.015 15.7 0.1 1.3 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal RVT_1 PF00078.22 EDN07810.1 - 5.2e-25 88.0 0.0 8.2e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN07810.1 - 6.6e-15 55.6 0.0 1.1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 RNase H Glyco_hydro_18 PF00704.23 EDN07813.1 - 1.6e-79 267.8 5.1 1.9e-79 267.6 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EDN07813.1 - 0.00082 19.3 7.7 0.0017 18.2 5.3 1.6 1 0 0 1 1 1 1 Chitin recognition protein DUF3142 PF11340.3 EDN07813.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) DUF1708 PF08101.6 EDN07814.1 - 1.6e-163 544.4 0.0 2.2e-163 543.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Mito_carr PF00153.22 EDN07815.1 - 5.6e-48 160.5 7.9 2e-18 65.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1065 PF06358.6 EDN07815.1 - 0.065 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) CBS PF00571.23 EDN07816.1 - 0.00019 21.1 0.0 0.94 9.3 0.0 3.4 2 1 0 2 2 2 2 CBS domain MFS_2 PF13347.1 EDN07817.1 - 3.3e-11 42.2 17.0 8e-11 40.9 1.5 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein Nuc_H_symport PF03825.11 EDN07817.1 - 0.012 14.4 0.4 0.012 14.4 0.3 3.3 4 1 0 4 4 4 0 Nucleoside H+ symporter MFS_1_like PF12832.2 EDN07817.1 - 0.018 14.8 2.6 0.27 11.0 0.0 3.4 2 0 0 2 2 2 0 MFS_1 like family DUF3040 PF11239.3 EDN07817.1 - 0.73 9.9 5.8 0.87 9.6 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) ABC2_membrane PF01061.19 EDN07818.1 - 1.3e-91 305.4 54.5 5.7e-47 159.6 16.6 3.2 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EDN07818.1 - 3.8e-36 122.8 8.8 4.5e-33 112.9 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EDN07818.1 - 4.6e-28 98.2 0.0 5.7e-17 62.2 0.0 3.0 3 1 1 4 4 3 2 ABC transporter ABC_trans_N PF14510.1 EDN07818.1 - 2.4e-21 75.6 0.0 8.6e-21 73.8 0.0 1.9 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 EDN07818.1 - 0.00032 20.7 0.1 0.00064 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EDN07818.1 - 0.00033 20.1 0.0 0.00084 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EDN07818.1 - 0.001 18.2 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EDN07818.1 - 0.0065 15.7 0.0 0.56 9.4 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDN07818.1 - 0.0072 15.8 0.2 0.018 14.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EDN07818.1 - 0.011 16.0 0.0 0.038 14.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EDN07818.1 - 0.021 14.7 0.1 2 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EDN07818.1 - 0.025 14.0 0.1 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EDN07818.1 - 0.077 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.2 EDN07818.1 - 0.086 11.8 48.1 0.02 13.9 13.2 3.1 2 1 0 2 2 2 0 ABC-2 family transporter protein AAA_17 PF13207.1 EDN07818.1 - 0.15 12.8 0.0 0.49 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain G6PD_C PF02781.11 EDN07819.1 - 1.7e-135 450.5 0.0 2.4e-135 450.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EDN07819.1 - 1.1e-54 185.5 0.0 2.2e-54 184.4 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MFS_1 PF07690.11 EDN07820.1 - 9.6e-46 156.0 45.4 8.3e-45 153.0 31.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN07820.1 - 1.9e-24 85.7 15.8 6e-24 84.1 10.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EDN07820.1 - 2.6e-10 39.4 10.9 2.6e-10 39.4 7.5 2.9 1 1 1 2 2 2 1 Sugar (and other) transporter DUF983 PF06170.7 EDN07820.1 - 0.84 9.7 6.6 0.96 9.6 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF983) EF-hand_1 PF00036.27 EDN07821.1 - 1.8e-19 67.4 5.5 1.8e-06 26.7 0.1 4.3 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EDN07821.1 - 3.8e-18 63.6 2.7 3.5e-05 23.3 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EDN07821.1 - 5.1e-17 61.2 3.8 2.2e-07 30.3 0.2 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_7 PF13499.1 EDN07821.1 - 5.7e-17 61.6 0.5 2.6e-09 37.0 0.2 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EDN07821.1 - 1.2e-12 46.5 4.0 0.00018 20.7 0.1 3.8 4 0 0 4 4 4 3 EF hand DUF1282 PF06930.7 EDN07821.1 - 0.016 14.8 0.0 0.18 11.4 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1282) ChaC PF04752.7 EDN07822.1 - 5.2e-20 72.1 0.0 7e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein RRM_1 PF00076.17 EDN07823.1 - 2.6e-22 78.2 0.0 3.4e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN07823.1 - 9.7e-17 60.7 0.0 1.2e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN07823.1 - 4.4e-10 39.2 0.0 5.8e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDN07823.1 - 0.096 12.5 0.1 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Herpes_US9 PF06072.6 EDN07824.1 - 0.061 13.1 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 eIF-5_eIF-2B PF01873.12 EDN07825.1 - 2.2e-43 146.8 0.3 3.7e-43 146.1 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EDN07825.1 - 0.075 13.3 0.6 0.27 11.5 0.4 2.0 1 1 0 1 1 1 0 Restriction alleviation protein Lar Arc_trans_TRASH PF08394.5 EDN07825.1 - 1.2 9.3 7.1 1.1 9.4 0.2 2.8 1 1 1 2 2 2 0 Archaeal TRASH domain Tyrosinase PF00264.15 EDN07826.1 - 3.1e-36 125.6 2.3 4.4e-36 125.1 1.6 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase AIM24 PF01987.12 EDN07827.1 - 1.3e-55 188.2 0.3 1.5e-55 187.9 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 SH3_1 PF00018.23 EDN07828.1 - 1.1e-13 50.3 0.0 1.5e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDN07828.1 - 6.7e-12 44.8 0.0 9.3e-12 44.3 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDN07828.1 - 5.4e-09 35.4 0.0 8e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain MBF1 PF08523.5 EDN07829.1 - 4.3e-23 81.1 0.0 8.5e-23 80.1 0.0 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EDN07829.1 - 2.3e-08 33.7 0.1 3.5e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EDN07829.1 - 0.00013 22.1 0.0 0.00026 21.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EDN07829.1 - 0.00058 19.8 0.1 0.00089 19.2 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Xpo1 PF08389.7 EDN07831.1 - 0.00055 19.8 2.2 0.03 14.2 0.0 3.0 3 0 0 3 3 3 2 Exportin 1-like protein Pkinase PF00069.20 EDN07832.1 - 8.4e-36 123.4 0.7 9.9e-36 123.2 0.5 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07832.1 - 6.7e-23 81.0 0.9 8.2e-23 80.7 0.6 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EDN07832.1 - 0.0045 16.3 0.4 0.0057 16.0 0.3 1.1 1 0 0 1 1 1 1 RIO1 family Cellulase PF00150.13 EDN07833.1 - 5.1e-10 39.0 1.5 1.9e-07 30.6 0.2 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) TPR_11 PF13414.1 EDN07834.1 - 9.3e-46 153.3 23.1 9.1e-08 31.6 0.0 11.3 9 3 2 11 11 10 8 TPR repeat TPR_2 PF07719.12 EDN07834.1 - 3.4e-28 95.2 30.2 0.0018 18.0 0.0 14.6 15 0 0 15 15 15 7 Tetratricopeptide repeat TPR_14 PF13428.1 EDN07834.1 - 7e-28 94.5 20.8 0.0063 17.0 0.1 14.1 12 5 2 14 14 13 6 Tetratricopeptide repeat TPR_12 PF13424.1 EDN07834.1 - 2.5e-26 91.3 25.9 0.00093 19.0 0.0 11.2 9 2 1 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 EDN07834.1 - 3e-26 89.3 1.5 0.004 17.2 0.0 12.6 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDN07834.1 - 9.5e-26 89.8 29.4 2e-06 28.2 0.3 10.9 12 1 0 12 12 10 5 Tetratricopeptide repeat TPR_1 PF00515.23 EDN07834.1 - 1.3e-25 87.9 28.2 0.00042 19.8 0.0 14.4 15 1 0 15 15 15 6 Tetratricopeptide repeat TPR_19 PF14559.1 EDN07834.1 - 1.5e-21 76.5 7.5 0.0014 18.9 0.0 9.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 EDN07834.1 - 1.1e-17 62.3 18.1 0.17 11.7 0.0 12.8 14 1 1 15 15 13 4 Tetratricopeptide repeat TPR_7 PF13176.1 EDN07834.1 - 4.4e-15 54.1 13.3 0.011 15.4 0.0 11.3 12 0 0 12 12 11 3 Tetratricopeptide repeat Apc3 PF12895.2 EDN07834.1 - 8.1e-11 41.9 6.1 0.00032 20.7 0.1 6.0 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDN07834.1 - 3.9e-10 39.5 26.5 0.96 10.0 0.0 13.1 15 0 0 15 15 14 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDN07834.1 - 0.00046 19.9 18.3 4.5 7.1 0.1 7.8 7 2 1 8 8 8 3 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 EDN07834.1 - 0.0029 16.4 0.3 0.29 9.8 0.0 2.4 2 0 0 2 2 2 1 Coatomer WD associated region Fis1_TPR_C PF14853.1 EDN07834.1 - 0.0058 16.4 1.1 53 3.8 0.0 5.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.9 EDN07834.1 - 0.011 14.9 0.8 0.12 11.5 0.0 2.9 2 1 1 3 3 3 0 Coatomer epsilon subunit Ribosomal_L12 PF00542.14 EDN07834.1 - 0.034 14.1 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain TPR_20 PF14561.1 EDN07834.1 - 0.74 9.9 0.0 0.74 9.9 0.0 6.0 8 0 0 8 8 8 0 Tetratricopeptide repeat Vps51 PF08700.6 EDN07835.1 - 9.8e-25 86.2 0.0 1.7e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 EDN07835.1 - 0.009 14.5 0.1 0.011 14.1 0.1 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 EDN07835.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Fes1 PF08609.5 EDN07835.1 - 0.08 13.4 0.3 0.35 11.3 0.0 2.1 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 WD40 PF00400.27 EDN07836.1 - 0.11 12.4 6.7 22 5.1 0.0 5.2 7 0 0 7 7 7 0 WD domain, G-beta repeat PCI_Csn8 PF10075.4 EDN07837.1 - 1.5e-07 31.2 0.0 2.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EDN07837.1 - 0.029 13.9 2.6 1.4 8.4 0.0 2.3 2 1 1 3 3 3 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Pro-kuma_activ PF09286.6 EDN07838.1 - 2.4e-30 105.4 0.0 4.2e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EDN07838.1 - 8.6e-07 28.3 0.1 1.3e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Subtilase family TBCC PF07986.7 EDN07839.1 - 3.9e-35 119.8 1.1 6.7e-35 119.1 0.7 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C IL32 PF15225.1 EDN07839.1 - 0.085 12.8 0.3 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Interleukin 32 DUF4463 PF14703.1 EDN07839.1 - 0.098 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) JAB PF01398.16 EDN07840.1 - 4.5e-16 58.6 0.0 9.3e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EDN07840.1 - 6.6e-09 35.7 0.1 1.3e-08 34.7 0.1 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 EDN07840.1 - 7.7e-06 25.4 0.0 1.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RrnaAD PF00398.15 EDN07841.1 - 7.2e-06 25.2 0.0 1.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Med3 PF11593.3 EDN07841.1 - 0.046 12.9 0.3 0.087 12.0 0.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase PF00069.20 EDN07842.1 - 1.6e-14 53.7 0.0 2.1e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07842.1 - 2.9e-05 23.2 0.0 0.0055 15.8 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EDN07842.1 - 0.0025 17.5 0.0 0.0039 16.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family ApbA_C PF08546.6 EDN07843.1 - 9.3e-27 93.5 0.0 1.6e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EDN07843.1 - 7.7e-26 90.3 0.0 1.1e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EDN07843.1 - 0.0025 17.6 1.8 0.0069 16.2 1.1 1.8 2 0 0 2 2 2 1 ThiF family Shikimate_DH PF01488.15 EDN07843.1 - 0.03 14.4 0.2 0.064 13.3 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EDN07843.1 - 0.059 12.4 0.1 0.078 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain WD40 PF00400.27 EDN07846.1 - 1.3e-29 100.9 1.5 1.2e-08 34.4 0.0 6.2 6 1 0 6 6 6 5 WD domain, G-beta repeat Gmad1 PF10647.4 EDN07846.1 - 0.0053 16.1 0.1 0.0088 15.4 0.1 1.4 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain eIF2A PF08662.6 EDN07846.1 - 0.018 14.7 0.2 1.4 8.5 0.0 2.8 2 2 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EDN07846.1 - 0.11 10.5 0.0 0.2 9.7 0.0 1.4 2 0 0 2 2 2 0 Nucleoporin Nup120/160 FTHFS PF01268.14 EDN07847.1 - 1e-256 852.3 0.1 1.3e-256 852.0 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EDN07847.1 - 2.4e-46 156.7 2.4 3.4e-46 156.2 0.2 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EDN07847.1 - 1.4e-36 125.0 0.3 6.7e-36 122.8 0.3 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.16 EDN07847.1 - 0.016 15.0 0.8 0.25 11.1 0.1 2.6 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Iso_dh PF00180.15 EDN07848.1 - 2.2e-42 145.2 0.0 1.9e-32 112.6 0.0 2.2 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase GRIM-19 PF06212.7 EDN07849.1 - 8.4e-12 44.9 0.2 9.8e-12 44.7 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.16 EDN07850.1 - 1.2e-28 99.9 0.0 1.1e-27 96.8 0.0 2.3 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase NARP1 PF12569.3 EDN07850.1 - 0.076 11.7 6.6 0.14 10.8 4.6 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 VID27 PF08553.5 EDN07851.1 - 6e-234 778.8 8.0 9.7e-226 751.6 2.4 2.1 1 1 1 2 2 2 2 VID27 cytoplasmic protein PQQ_2 PF13360.1 EDN07851.1 - 0.016 14.6 0.0 0.059 12.8 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain TLD PF07534.11 EDN07852.1 - 4.1e-25 88.3 0.0 5.8e-15 55.4 0.0 2.4 2 0 0 2 2 2 2 TLD Adaptin_N PF01602.15 EDN07853.1 - 2.3e-139 465.1 1.7 2.7e-139 464.9 1.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EDN07853.1 - 5.5e-28 98.0 0.4 9.2e-25 87.5 0.0 2.9 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EDN07853.1 - 3.6e-18 65.6 2.1 1e-06 28.8 0.0 5.7 3 1 3 6 6 6 3 HEAT repeats HEAT PF02985.17 EDN07853.1 - 9.2e-12 44.0 4.1 0.0022 17.9 0.0 5.4 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EDN07853.1 - 8.1e-05 22.9 4.0 4.1 8.0 0.0 6.8 7 1 1 8 8 8 1 HEAT-like repeat Arm PF00514.18 EDN07853.1 - 0.00042 20.0 0.4 1.9 8.4 0.0 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat AF0941-like PF14591.1 EDN07853.1 - 0.0096 15.9 0.7 0.085 12.9 0.5 2.3 2 0 0 2 2 2 1 AF0941-like CLASP_N PF12348.3 EDN07853.1 - 0.032 13.5 0.2 4.4 6.5 0.0 3.4 3 1 0 3 3 3 0 CLASP N terminal Atx10homo_assoc PF09759.4 EDN07853.1 - 0.049 13.3 0.0 0.52 10.0 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DEK_C PF08766.6 EDN07854.1 - 0.0021 17.7 0.1 0.0072 16.0 0.1 1.9 1 0 0 1 1 1 1 DEK C terminal domain ATHILA PF03078.10 EDN07854.1 - 0.086 11.4 1.2 2.1 6.8 0.0 2.4 2 0 0 2 2 2 0 ATHILA ORF-1 family PLRV_ORF5 PF01690.12 EDN07854.1 - 6.2 5.8 22.9 8.7 5.3 15.9 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Evr1_Alr PF04777.8 EDN07855.1 - 5.3e-09 35.8 0.2 1.8e-08 34.1 0.1 1.8 2 0 0 2 2 2 1 Erv1 / Alr family LAT PF15234.1 EDN07855.1 - 0.13 11.7 4.3 0.18 11.2 3.0 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells Med3 PF11593.3 EDN07855.1 - 3.8 6.6 11.0 4.2 6.5 7.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Coatomer_WDAD PF04053.9 EDN07856.1 - 1.6e-144 482.0 0.0 2.4e-144 481.4 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EDN07856.1 - 8.6e-97 324.3 0.0 1.3e-96 323.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EDN07856.1 - 4.1e-48 159.6 12.7 8.9e-09 34.9 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EDN07856.1 - 0.0076 14.4 6.0 0.47 8.5 0.0 3.4 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Clathrin PF00637.15 EDN07856.1 - 0.0089 15.6 0.4 0.083 12.4 0.0 2.7 3 1 0 3 3 3 1 Region in Clathrin and VPS Phytase-like PF13449.1 EDN07858.1 - 1.4e-28 100.1 0.0 2.2e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase DUF2335 PF10097.4 EDN07859.1 - 1.7 8.3 5.0 4 7.1 3.5 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Selenoprotein_S PF06936.6 EDN07859.1 - 6.8 6.1 10.8 3.3 7.1 5.2 1.9 2 0 0 2 2 2 0 Selenoprotein S (SelS) Clr5 PF14420.1 EDN07860.1 - 5.4e-21 74.2 1.7 1.7e-20 72.6 1.2 1.9 1 0 0 1 1 1 1 Clr5 domain TAXi_C PF14541.1 EDN07860.1 - 0.034 13.7 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal DUF2407_C PF13373.1 EDN07860.1 - 0.084 12.7 0.4 0.24 11.2 0.1 1.9 2 0 0 2 2 2 0 DUF2407 C-terminal domain Sensor PF13796.1 EDN07860.1 - 0.61 9.6 2.1 1.4 8.4 1.5 1.6 1 0 0 1 1 1 0 Putative sensor Het-C PF07217.6 EDN07861.1 - 9.2e-256 849.8 0.0 9.2e-256 849.8 0.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein Het-C DUF2828 PF11443.3 EDN07862.1 - 1.3e-143 479.0 0.1 1.7e-90 303.7 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF2828) FAD-oxidase_C PF02913.14 EDN07863.1 - 5e-58 196.3 0.0 9.4e-58 195.4 0.0 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EDN07863.1 - 7.7e-37 125.8 0.0 1.5e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_2 PF00703.16 EDN07864.1 - 4.8e-11 43.0 1.5 8.6e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EDN07864.1 - 2.9e-08 33.4 0.0 1e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DDE_1 PF03184.14 EDN07865.1 - 1.7e-36 125.3 0.0 3.2e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN07865.1 - 4.3e-11 42.4 0.3 9.6e-10 38.1 0.0 3.0 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain PFL PF02901.10 EDN07865.1 - 0.0077 14.7 0.7 0.014 13.8 0.5 1.4 1 0 0 1 1 1 1 Pyruvate formate lyase ADH_N PF08240.7 EDN07866.1 - 2.8e-32 110.7 0.0 5e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN07866.1 - 3.7e-05 23.2 0.1 6.9e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EDN07866.1 - 0.0019 18.7 0.0 0.0035 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 EDN07866.1 - 0.0077 15.8 0.3 0.011 15.2 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EDN07866.1 - 0.019 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EDN07866.1 - 0.02 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.16 EDN07866.1 - 0.058 13.2 0.1 0.17 11.7 0.1 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CPSase_L_chain PF00289.17 EDN07866.1 - 0.082 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Methyltransf_11 PF08241.7 EDN07866.1 - 0.084 13.3 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EDN07866.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ras PF00071.17 EDN07867.1 - 1.2e-05 24.7 0.0 4.4e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Ras family PAF-AH_p_II PF03403.8 EDN07868.1 - 5.8e-38 130.1 0.0 1e-34 119.4 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EDN07868.1 - 7.3e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EDN07868.1 - 8.3e-05 21.5 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 EDN07868.1 - 0.0019 17.1 0.0 0.0036 16.2 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EDN07868.1 - 0.029 14.2 0.1 0.14 11.9 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family Na_Ca_ex PF01699.19 EDN07869.1 - 3.8e-06 26.5 2.8 7.1e-06 25.6 2.0 1.6 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF4081 PF13312.1 EDN07870.1 - 0.12 12.3 0.5 0.99 9.3 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4081) Glyco_tranf_2_3 PF13641.1 EDN07873.1 - 1.4e-22 80.6 0.0 1.7e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EDN07873.1 - 1.8e-09 37.5 0.0 2.9e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EDN07873.1 - 2e-08 33.7 0.0 2.9e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 ATP12 PF07542.6 EDN07875.1 - 2.3e-32 111.5 0.1 3.3e-32 111.0 0.1 1.1 1 0 0 1 1 1 1 ATP12 chaperone protein Oxysterol_BP PF01237.13 EDN07876.1 - 5.6e-134 446.0 0.0 1.2e-133 445.0 0.0 1.6 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 EDN07876.1 - 3.4e-18 65.7 0.0 8.5e-12 45.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDN07876.1 - 1.3e-17 62.6 0.7 7e-06 25.5 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EDN07876.1 - 1.2e-16 60.3 1.0 2.2e-09 37.2 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN07876.1 - 1.7e-15 57.0 0.2 1e-07 32.2 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN07876.1 - 3e-15 54.8 0.0 1.2e-05 25.1 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat PH_11 PF15413.1 EDN07876.1 - 3.8e-09 36.7 1.5 7.1e-09 35.9 0.2 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EDN07876.1 - 4.9e-07 29.9 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EDN07876.1 - 0.00023 21.1 0.2 0.00057 19.9 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain ERM PF00769.14 EDN07876.1 - 0.0028 17.2 3.2 0.0028 17.2 2.2 2.1 2 0 0 2 2 2 1 Ezrin/radixin/moesin family HisKA PF00512.20 EDN07876.1 - 0.036 14.0 0.1 0.13 12.2 0.1 2.0 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain LLC1 PF14945.1 EDN07876.1 - 1.8 8.9 8.4 0.17 12.2 1.3 2.3 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein zf-Mss51 PF13824.1 EDN07877.1 - 2.4e-28 97.7 6.1 2.4e-28 97.7 4.2 2.4 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 EDN07877.1 - 0.017 14.9 0.5 0.017 14.9 0.4 2.2 2 0 0 2 2 2 0 MYND finger ADH_zinc_N PF00107.21 EDN07879.1 - 1.8e-30 105.1 0.7 2.7e-30 104.5 0.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN07879.1 - 9.8e-07 28.5 0.0 3.4e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EDN07879.1 - 0.012 16.4 0.2 0.039 14.8 0.0 2.0 3 0 0 3 3 3 0 Zinc-binding dehydrogenase HupF_HypC PF01455.13 EDN07879.1 - 0.17 11.9 0.3 1.9 8.5 0.1 2.4 2 0 0 2 2 2 0 HupF/HypC family Pep_deformylase PF01327.16 EDN07879.1 - 0.18 11.2 0.1 0.31 10.4 0.1 1.3 1 0 0 1 1 1 0 Polypeptide deformylase HET PF06985.6 EDN07881.1 - 1.8e-29 102.6 0.0 3.1e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clr5 PF14420.1 EDN07882.1 - 1.9e-13 50.0 0.4 3.2e-13 49.3 0.3 1.4 1 0 0 1 1 1 1 Clr5 domain SNF2_N PF00176.18 EDN07883.1 - 1.1e-49 168.8 1.6 8.2e-49 166.0 1.1 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EDN07883.1 - 2e-06 27.7 0.0 0.00061 19.6 0.0 3.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.8 EDN07883.1 - 3.3e-05 23.6 7.7 0.00016 21.3 5.3 2.3 1 0 0 1 1 1 1 HSA NDUF_B8 PF05821.6 EDN07884.1 - 6.6e-05 22.6 0.1 7.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Membr_traf_MHD PF10540.4 EDN07886.1 - 3.4e-26 91.6 0.1 5.3e-25 87.7 0.0 2.5 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EDN07886.1 - 1.3e-15 56.9 0.0 3e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_2 PF09068.6 EDN07886.1 - 0.044 13.8 0.0 0.2 11.7 0.0 2.2 1 0 0 1 1 1 0 EF hand Ribonuc_L-PSP PF01042.16 EDN07887.1 - 4.2e-40 136.2 0.0 4.6e-40 136.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sigma54_DBD PF04552.8 EDN07887.1 - 0.15 11.5 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Sigma-54, DNA binding domain MFS_1 PF07690.11 EDN07889.1 - 2.7e-26 92.1 21.0 1.7e-25 89.4 14.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN07889.1 - 0.31 9.5 12.7 0.025 13.1 4.0 2.3 2 1 0 2 2 2 0 Sugar (and other) transporter DUF202 PF02656.10 EDN07889.1 - 0.91 9.7 3.5 18 5.6 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Glyco_hydro_47 PF01532.15 EDN07890.1 - 4e-133 444.3 0.0 5.1e-133 444.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MRAP PF15183.1 EDN07891.1 - 0.18 11.4 0.5 0.32 10.6 0.4 1.5 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family WD40 PF00400.27 EDN07892.1 - 9.9e-56 183.7 11.0 2.7e-08 33.3 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EDN07892.1 - 0.0016 17.2 2.2 0.12 11.1 0.2 2.8 2 2 0 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 EDN07892.1 - 0.039 13.4 0.1 9.5 5.6 0.0 2.8 2 1 1 3 3 3 0 PQQ-like domain TRAPP PF04051.11 EDN07893.1 - 2.1e-37 127.9 0.0 2.6e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.1 EDN07893.1 - 0.028 14.1 0.1 0.054 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) LisH PF08513.6 EDN07894.1 - 0.0003 20.4 0.2 0.00057 19.5 0.1 1.4 1 0 0 1 1 1 1 LisH DND1_DSRM PF14709.1 EDN07898.1 - 0.00048 20.3 1.7 0.005 17.0 0.4 3.1 2 2 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 RRM_1 PF00076.17 EDN07900.1 - 9.7e-45 150.0 0.0 8.5e-17 60.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN07900.1 - 1.4e-26 92.2 0.0 2.1e-09 37.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN07900.1 - 2.4e-20 72.1 0.0 2.8e-08 33.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDN07900.1 - 1.5e-05 24.7 0.0 0.00011 22.0 0.0 2.2 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EDN07900.1 - 0.00046 19.8 0.0 0.0092 15.7 0.0 2.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif UPF0086 PF01868.11 EDN07901.1 - 0.22 11.1 1.5 0.31 10.7 0.6 1.5 2 0 0 2 2 2 0 Domain of unknown function UPF0086 RRP7 PF12923.2 EDN07903.1 - 4.2e-31 107.6 11.0 8e-31 106.7 7.6 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_6 PF14259.1 EDN07903.1 - 0.025 14.5 0.1 0.23 11.4 0.0 2.6 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN07903.1 - 0.028 14.0 0.1 1.8 8.2 0.0 3.0 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad51 PF08423.6 EDN07904.1 - 2.7e-119 396.7 0.5 4.4e-88 294.4 0.1 2.2 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.1 EDN07904.1 - 2.6e-10 40.0 0.0 4.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EDN07904.1 - 2.1e-09 36.8 0.0 2.7e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 EDN07904.1 - 5.8e-09 35.9 1.3 1.3e-08 34.9 0.1 2.1 3 0 0 3 3 3 1 Helix-hairpin-helix domain KaiC PF06745.8 EDN07904.1 - 1e-06 28.0 0.0 2.9e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 KaiC DUF128 PF01995.11 EDN07904.1 - 0.079 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF128 RNA_pol_A_CTD PF03118.10 EDN07904.1 - 0.099 12.0 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain zf-CCHC PF00098.18 EDN07905.1 - 9.1e-30 101.1 36.5 8.9e-08 31.7 0.8 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.1 EDN07905.1 - 1.2e-07 31.2 27.1 0.087 12.4 0.5 6.0 6 0 0 6 6 6 4 Zinc knuckle zf-CCHC_3 PF13917.1 EDN07905.1 - 3.8e-07 29.7 17.2 0.12 12.0 0.0 5.2 4 1 1 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.1 EDN07905.1 - 0.00045 19.6 31.6 0.32 10.5 1.0 6.0 5 1 1 6 6 6 3 Zinc knuckle zf-TRAF PF02176.13 EDN07905.1 - 0.08 13.3 13.1 5.4 7.4 0.1 4.7 2 2 2 5 5 5 0 TRAF-type zinc finger zf-CCHC_6 PF15288.1 EDN07905.1 - 7.4 6.3 31.7 0.19 11.4 1.4 5.1 5 0 0 5 5 5 0 Zinc knuckle UDPGP PF01704.13 EDN07906.1 - 3.7e-54 183.8 0.0 5.1e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EDN07906.1 - 0.11 12.5 0.0 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 MobA-like NTP transferase domain Pro_isomerase PF00160.16 EDN07907.1 - 5.6e-35 120.8 0.0 8e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EDN07907.1 - 3.8e-16 58.4 0.0 7.7e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN07907.1 - 8.2e-12 44.9 0.1 2.6e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN07907.1 - 1.9e-10 40.4 0.0 7e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDN07907.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ribosomal_S24e PF01282.14 EDN07908.1 - 2.4e-33 113.7 0.1 3.6e-33 113.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Methyltransf_16 PF10294.4 EDN07909.1 - 1.2e-12 47.6 0.0 1.9e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EDN07909.1 - 1.8e-06 28.5 0.0 2.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDN07909.1 - 0.00015 21.0 0.0 0.0002 20.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EDN07909.1 - 0.00018 20.9 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EDN07909.1 - 0.0014 19.0 0.0 0.0033 17.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EDN07909.1 - 0.0017 17.4 0.0 0.0022 17.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 EDN07909.1 - 0.014 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EDN07909.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_11 PF08241.7 EDN07909.1 - 0.098 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GAGA_bind PF06217.7 EDN07910.1 - 0.42 10.5 7.5 0.99 9.3 5.2 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family DUF869 PF05911.6 EDN07910.1 - 0.5 8.5 21.5 0.4 8.8 13.9 1.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) DivIVA PF05103.8 EDN07910.1 - 1.1 9.2 0.0 1.1 9.2 0.0 3.4 2 1 0 2 2 2 0 DivIVA protein GAS PF13851.1 EDN07910.1 - 1.7 7.8 23.0 0.083 12.0 10.2 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding RED_C PF07807.6 EDN07911.1 - 0.027 14.6 0.4 0.031 14.4 0.3 1.1 1 0 0 1 1 1 0 RED-like protein C-terminal region Pal1 PF08316.6 EDN07911.1 - 0.12 12.7 0.1 0.13 12.7 0.1 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein V-ATPase_G PF03179.10 EDN07912.1 - 3e-28 98.1 12.3 3.5e-28 97.9 8.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DXP_synthase_N PF13292.1 EDN07912.1 - 0.0031 16.4 0.1 0.0039 16.1 0.1 1.1 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Exonuc_VII_L PF02601.10 EDN07912.1 - 0.016 14.4 2.9 0.018 14.2 2.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HypD PF01924.11 EDN07912.1 - 0.043 12.5 1.7 0.051 12.3 1.2 1.0 1 0 0 1 1 1 0 Hydrogenase formation hypA family DUF2201_N PF13203.1 EDN07912.1 - 0.11 11.5 4.9 0.13 11.4 3.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2203 PF09969.4 EDN07912.1 - 0.23 11.6 4.0 0.28 11.4 2.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF2151 PF10221.4 EDN07912.1 - 0.41 8.7 4.1 0.41 8.7 2.8 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator OmpH PF03938.9 EDN07912.1 - 0.46 10.4 9.5 0.52 10.2 6.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Med8 PF10232.4 EDN07912.1 - 0.55 9.6 5.1 0.64 9.4 3.6 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 ATP-synt_B PF00430.13 EDN07912.1 - 3.5 7.4 15.8 25 4.6 11.0 2.0 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Arrestin_N PF00339.24 EDN07914.1 - 2e-09 37.4 0.0 2.4e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Pyr_redox_2 PF07992.9 EDN07916.1 - 5.7e-30 104.6 0.0 1.4e-29 103.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN07916.1 - 5.8e-14 52.2 0.4 1.8e-11 44.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EDN07916.1 - 1.2e-12 47.2 0.0 2.4e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EDN07916.1 - 5.5e-07 29.8 0.0 0.0028 17.7 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EDN07916.1 - 2.5e-05 24.5 0.0 6.8e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 EDN07916.1 - 9.3e-05 21.4 0.1 0.31 9.9 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EDN07916.1 - 0.00034 20.4 0.3 0.8 9.4 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EDN07916.1 - 0.00049 19.1 0.4 1.3 7.8 0.0 4.0 4 1 0 4 4 4 1 FAD dependent oxidoreductase Rieske_2 PF13806.1 EDN07916.1 - 0.00054 19.6 0.0 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF1188 PF06690.6 EDN07916.1 - 0.0098 15.0 0.1 0.016 14.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) TrkA_N PF02254.13 EDN07916.1 - 0.014 15.3 2.0 1.4 8.9 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.1 EDN07916.1 - 0.016 15.4 0.2 0.15 12.3 0.0 2.2 1 1 1 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 EDN07916.1 - 0.019 13.4 0.2 5.3 5.3 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein Malic_M PF03949.10 EDN07916.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain AlaDh_PNT_C PF01262.16 EDN07916.1 - 0.077 12.5 2.0 0.41 10.2 0.0 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.20 EDN07916.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain SHS2_Rpb7-N PF03876.12 EDN07917.1 - 7e-06 26.0 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DnaJ PF00226.26 EDN07918.1 - 1.2e-13 50.6 0.1 2.1e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain SPRY PF00622.23 EDN07919.1 - 1.3e-16 60.7 0.4 2.1e-16 60.1 0.3 1.3 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 EDN07919.1 - 8e-16 58.0 0.0 1.4e-15 57.2 0.0 1.4 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EDN07919.1 - 0.016 14.9 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 LisH Glyco_hydro_16 PF00722.16 EDN07921.1 - 1.4e-05 24.4 0.2 2.1e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 IDO PF01231.13 EDN07922.1 - 4.7e-29 101.0 0.0 1.5e-24 86.1 0.0 2.5 2 1 0 2 2 2 2 Indoleamine 2,3-dioxygenase TPR_11 PF13414.1 EDN07923.1 - 9.7e-06 25.1 1.1 0.035 13.7 0.1 2.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDN07923.1 - 0.00016 21.3 2.4 0.35 10.8 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat LRR_4 PF12799.2 EDN07923.1 - 0.00023 20.7 20.9 0.0013 18.3 0.1 6.0 2 2 4 6 6 6 1 Leucine Rich repeats (2 copies) TPR_1 PF00515.23 EDN07923.1 - 0.00032 20.1 0.2 0.038 13.6 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDN07923.1 - 0.00075 19.3 1.0 0.48 10.3 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat LRR_8 PF13855.1 EDN07923.1 - 0.003 17.2 10.7 1.5 8.6 0.4 5.0 3 1 3 6 6 6 3 Leucine rich repeat Apc3 PF12895.2 EDN07923.1 - 0.0034 17.4 0.2 1.7 8.8 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 LRR_6 PF13516.1 EDN07923.1 - 0.0068 16.3 9.1 2.2 8.5 0.0 5.7 7 0 0 7 7 5 1 Leucine Rich repeat TPR_9 PF13371.1 EDN07923.1 - 0.017 14.9 0.6 0.53 10.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDN07923.1 - 0.023 15.3 3.2 5.8 7.8 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDN07923.1 - 0.059 14.0 3.2 3.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat FNIP PF05725.7 EDN07923.1 - 0.11 12.4 3.4 7.7 6.5 0.4 4.3 4 2 0 4 4 3 0 FNIP Repeat TPR_6 PF13174.1 EDN07923.1 - 0.12 12.9 4.9 1.1 9.8 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDN07923.1 - 0.13 12.0 3.1 0.63 9.9 0.0 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat LRR_7 PF13504.1 EDN07923.1 - 0.2 12.0 9.6 5.4 7.6 0.2 6.7 9 0 0 9 9 6 0 Leucine rich repeat LRR_1 PF00560.28 EDN07923.1 - 0.42 10.8 10.5 4.6 7.6 0.0 5.6 6 0 0 6 6 5 0 Leucine Rich Repeat ADIP PF11559.3 EDN07924.1 - 7.4e-27 94.1 16.7 7.4e-27 94.1 11.6 3.6 4 2 0 4 4 4 1 Afadin- and alpha -actinin-Binding ATP-grasp PF02222.17 EDN07925.1 - 0.08 12.2 0.0 0.09 12.1 0.0 1.0 1 0 0 1 1 1 0 ATP-grasp domain Nucleopor_Nup85 PF07575.8 EDN07927.1 - 6.6e-24 84.0 0.0 9.6e-22 76.9 0.0 3.1 1 1 0 1 1 1 1 Nup85 Nucleoporin DUF3425 PF11905.3 EDN07929.1 - 1.3e-16 60.7 4.7 1.3e-16 60.7 3.2 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3425) Fungal_trans PF04082.13 EDN07929.1 - 0.0056 15.5 0.1 0.01 14.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Golgin_A5 PF09787.4 EDN07930.1 - 0.35 9.3 3.4 0.46 8.9 2.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 RNA_pol_Rpb2_6 PF00562.23 EDN07931.1 - 2.5e-124 414.9 0.1 4.7e-124 414.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EDN07931.1 - 2.6e-61 206.0 0.0 4.4e-61 205.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EDN07931.1 - 6e-48 162.7 0.0 1.2e-47 161.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EDN07931.1 - 7.7e-31 106.1 0.0 1.7e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EDN07931.1 - 4e-25 87.4 0.9 1.1e-24 86.0 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EDN07931.1 - 3.8e-24 84.3 0.3 1e-23 83.0 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EDN07931.1 - 2e-22 78.7 1.2 2.6e-22 78.3 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 adh_short PF00106.20 EDN07933.1 - 1.4e-17 64.1 0.0 1.7e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN07933.1 - 5.3e-10 39.4 0.0 7.1e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.21 EDN07933.1 - 0.0031 17.0 0.0 0.0054 16.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.5 EDN07933.1 - 0.029 14.0 0.0 0.056 13.1 0.0 1.5 1 1 0 1 1 1 0 KR domain DUF294 PF03445.8 EDN07933.1 - 0.038 13.6 0.1 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 RNB PF00773.14 EDN07934.1 - 1.8e-39 135.9 0.0 3.3e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 RNB domain MARVEL PF01284.18 EDN07935.1 - 6e-06 26.1 4.4 7.7e-06 25.7 3.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain CytB6-F_Fe-S PF08802.5 EDN07935.1 - 0.012 15.5 0.8 0.035 14.1 0.5 1.8 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit Papilloma_E5 PF03025.9 EDN07935.1 - 0.5 10.3 8.4 0.089 12.7 3.2 1.7 2 0 0 2 2 2 0 Papillomavirus E5 DUF4229 PF14012.1 EDN07935.1 - 7.6 6.5 7.6 1.4 8.8 2.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Ras PF00071.17 EDN07936.1 - 0.00017 21.0 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 Ras family MAPEG PF01124.13 EDN07937.1 - 3.4e-15 55.7 1.9 4e-15 55.5 1.3 1.1 1 0 0 1 1 1 1 MAPEG family DPPIV_N PF00930.16 EDN07939.1 - 3e-111 371.4 2.4 4.2e-111 370.9 1.7 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EDN07939.1 - 9.1e-40 136.1 0.8 1.6e-39 135.3 0.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDN07939.1 - 7.2e-07 29.0 0.1 1.5e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN07939.1 - 0.00074 19.4 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 EDN07939.1 - 0.037 13.6 0.8 1.5 8.5 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Mannosyl_trans3 PF11051.3 EDN07940.1 - 1.8e-79 266.8 0.0 6.7e-79 265.0 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative ABC2_membrane PF01061.19 EDN07941.1 - 7.7e-31 106.8 31.8 9.7e-31 106.5 22.0 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EDN07941.1 - 1.9e-26 93.0 0.0 3.5e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EDN07941.1 - 1.8e-08 34.7 0.8 2e-05 24.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDN07941.1 - 7.2e-06 26.1 0.0 1.6e-05 24.9 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain DUF258 PF03193.11 EDN07941.1 - 4.9e-05 22.5 0.1 9.6e-05 21.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 EDN07941.1 - 0.00025 20.5 0.0 0.00049 19.5 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EDN07941.1 - 0.00077 18.9 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDN07941.1 - 0.0009 19.3 0.0 0.0029 17.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN07941.1 - 0.0011 19.7 0.0 0.0023 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN07941.1 - 0.0015 18.2 0.1 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EDN07941.1 - 0.0016 18.4 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EDN07941.1 - 0.0017 18.1 0.1 0.0042 16.8 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_29 PF13555.1 EDN07941.1 - 0.0023 17.4 0.1 0.0057 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EDN07941.1 - 0.0028 16.2 0.5 0.26 9.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EDN07941.1 - 0.0029 17.0 0.0 0.0092 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 EDN07941.1 - 0.0031 17.7 0.3 0.0082 16.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EDN07941.1 - 0.0052 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EDN07941.1 - 0.0078 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 EDN07941.1 - 0.0091 16.2 0.4 0.054 13.6 0.1 2.3 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 EDN07941.1 - 0.011 14.8 0.0 2.6 6.9 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain NACHT PF05729.7 EDN07941.1 - 0.012 15.3 0.0 0.029 14.0 0.0 1.7 2 0 0 2 2 1 0 NACHT domain AAA_14 PF13173.1 EDN07941.1 - 0.017 15.0 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EDN07941.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EDN07941.1 - 0.036 14.0 0.0 0.098 12.6 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EDN07941.1 - 0.045 13.2 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 EDN07941.1 - 0.049 12.5 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SbcCD_C PF13558.1 EDN07941.1 - 0.06 13.2 0.0 0.24 11.3 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 EDN07941.1 - 0.065 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RuvB_N PF05496.7 EDN07941.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EDN07941.1 - 0.074 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SMC_N PF02463.14 EDN07941.1 - 0.1 11.7 0.1 8.3 5.5 0.0 2.4 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.12 EDN07941.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein MobB PF03205.9 EDN07941.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EDN07941.1 - 0.13 12.6 1.9 0.27 11.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EDN07941.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 NTPase ABC2_membrane_3 PF12698.2 EDN07941.1 - 4.9 6.0 33.0 13 4.7 22.9 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein Fungal_trans PF04082.13 EDN07942.1 - 1.7e-10 40.2 0.0 2.5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GFA PF04828.9 EDN07943.1 - 6.9e-22 77.1 0.7 6.9e-22 77.1 0.5 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Cys_Met_Meta_PP PF01053.15 EDN07945.1 - 4.1e-59 199.8 0.0 1.2e-58 198.2 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EDN07945.1 - 0.00021 20.4 0.1 0.076 12.0 0.0 2.6 3 0 0 3 3 3 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EDN07945.1 - 0.0013 17.7 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EDN07945.1 - 0.0031 16.2 0.0 0.0085 14.8 0.0 1.6 1 1 1 2 2 2 1 Aminotransferase class-V DUF3665 PF12427.3 EDN07946.1 - 0.28 10.5 2.4 0.71 9.2 1.6 1.7 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase TRP PF06011.7 EDN07947.1 - 4.6e-86 289.1 26.0 2.5e-85 286.6 18.1 1.9 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EDN07947.1 - 3.6e-16 59.4 0.0 5.5e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 ML-like domain FYVE PF01363.16 EDN07948.1 - 3.2e-20 71.7 3.6 3.2e-20 71.7 2.5 3.2 4 0 0 4 4 4 1 FYVE zinc finger Zn_clus PF00172.13 EDN07948.1 - 4.6e-05 23.2 12.1 4.6e-05 23.2 8.4 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FYVE_2 PF02318.11 EDN07948.1 - 0.036 13.9 0.4 0.036 13.9 0.3 2.6 3 0 0 3 3 3 0 FYVE-type zinc finger Rad50_zn_hook PF04423.9 EDN07948.1 - 0.043 13.2 0.4 11 5.5 0.0 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif YiaAB PF05360.9 EDN07948.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 yiaA/B two helix domain zf-RING_2 PF13639.1 EDN07948.1 - 3.3 7.6 22.3 0.43 10.4 2.5 3.4 3 0 0 3 3 3 0 Ring finger domain NAD_binding_10 PF13460.1 EDN07949.1 - 6.3e-06 26.3 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDN07949.1 - 1.6e-05 24.4 0.0 3.1e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EDN07949.1 - 0.0012 17.8 0.0 0.2 10.5 0.0 2.6 3 0 0 3 3 3 2 Male sterility protein Semialdhyde_dh PF01118.19 EDN07949.1 - 0.054 13.8 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.11 EDN07950.1 - 7.7e-14 51.1 20.5 7.7e-14 51.1 14.2 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidase PF01425.16 EDN07951.1 - 2e-72 244.4 0.0 5.5e-72 243.0 0.0 1.7 1 1 0 1 1 1 1 Amidase zf-CCCH PF00642.19 EDN07953.1 - 1.8e-08 33.8 17.3 4e-07 29.5 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EDN07953.1 - 0.00016 21.4 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN07953.1 - 0.013 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN07953.1 - 0.1 12.6 0.0 0.28 11.1 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) UDPGP PF01704.13 EDN07957.1 - 5.6e-181 601.6 0.1 6.5e-181 601.4 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase RRM_1 PF00076.17 EDN07958.1 - 2.5e-16 59.0 0.0 5.5e-12 45.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN07958.1 - 1.1e-12 47.6 0.0 1.6e-08 34.4 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN07958.1 - 1.1e-08 34.7 0.0 9.5e-06 25.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) C2 PF00168.25 EDN07959.1 - 2.3e-65 216.4 0.2 1.7e-18 66.2 0.0 5.7 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 EDN07959.1 - 0.12 12.4 0.0 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) B56 PF01603.15 EDN07959.1 - 0.2 10.1 0.1 0.31 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) MFS_1 PF07690.11 EDN07960.1 - 2.9e-10 39.4 14.5 2.9e-10 39.4 10.0 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily TPR_11 PF13414.1 EDN07961.1 - 1.6e-51 171.8 21.0 3.7e-15 55.3 1.7 6.3 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 EDN07961.1 - 1.3e-40 135.3 19.3 6.5e-05 22.3 0.0 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EDN07961.1 - 8.9e-30 100.1 25.0 0.00012 21.6 0.0 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 EDN07961.1 - 2.5e-17 63.0 14.4 0.0025 18.4 0.0 6.6 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 EDN07961.1 - 9.6e-15 53.7 13.7 0.023 15.2 0.1 9.3 6 3 4 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 EDN07961.1 - 1.3e-14 53.8 13.3 1.6e-07 31.1 0.0 6.0 3 3 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDN07961.1 - 2.5e-12 46.9 16.5 0.0094 16.2 0.0 6.6 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EDN07961.1 - 5.3e-11 41.4 19.6 0.27 11.0 0.0 8.3 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 EDN07961.1 - 3.4e-09 36.1 9.0 0.29 11.4 0.0 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDN07961.1 - 8.9e-09 34.5 7.9 0.015 15.0 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EDN07961.1 - 4.4e-08 32.8 6.3 0.0025 17.6 0.5 4.9 4 2 1 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EDN07961.1 - 5.4e-07 29.6 4.4 0.007 16.4 0.1 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDN07961.1 - 5.2e-05 23.4 15.2 5.3 7.7 0.0 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat Inhibitor_I9 PF05922.11 EDN07961.1 - 0.0011 19.4 0.0 0.0041 17.6 0.0 2.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 Fis1_TPR_C PF14853.1 EDN07961.1 - 0.016 15.0 2.8 1.4 8.8 0.0 4.6 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat DUF627 PF04781.7 EDN07961.1 - 0.065 12.8 0.7 7.9 6.1 0.0 3.6 3 2 2 5 5 5 0 Protein of unknown function (DUF627) TPR_10 PF13374.1 EDN07961.1 - 0.14 12.1 1.6 2.7 8.0 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Trypan_PARP PF05887.6 EDN07961.1 - 0.52 10.1 18.0 3.9 7.2 10.6 2.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Alkyl_sulf_dimr PF14863.1 EDN07961.1 - 1.3 9.2 12.5 9.6 6.4 0.0 4.0 4 0 0 4 4 3 0 Alkyl sulfatase dimerisation TPR_3 PF07720.7 EDN07961.1 - 2.1 8.2 10.8 18 5.2 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat RNA_pol_Rpc34 PF05158.7 EDN07962.1 - 8.2e-108 360.4 0.0 9.8e-108 360.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit HTH_36 PF13730.1 EDN07962.1 - 0.0091 16.1 0.1 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 EDN07962.1 - 0.023 14.3 0.1 0.063 12.9 0.1 1.8 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.15 EDN07962.1 - 0.062 13.4 0.1 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator MarR PF01047.17 EDN07962.1 - 0.064 12.9 0.2 0.21 11.3 0.1 1.9 2 0 0 2 2 2 0 MarR family ING PF12998.2 EDN07963.1 - 2.4e-23 82.4 4.8 4.6e-23 81.5 3.4 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EDN07963.1 - 2.7e-08 33.3 10.1 4.8e-08 32.5 7.0 1.4 1 0 0 1 1 1 1 PHD-finger DUF4200 PF13863.1 EDN07963.1 - 0.0029 17.5 1.5 0.1 12.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) Hist_deacetyl PF00850.14 EDN07964.1 - 5.8e-78 262.3 0.1 8.2e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain HTH_Tnp_1 PF01527.15 EDN07965.1 - 0.013 15.4 0.0 0.019 14.8 0.0 1.4 1 1 0 1 1 1 0 Transposase Oxysterol_BP PF01237.13 EDN07966.1 - 2.5e-68 230.1 0.0 6e-49 166.4 0.0 2.2 1 1 1 2 2 2 2 Oxysterol-binding protein DUF3605 PF12239.3 EDN07967.1 - 2.5e-49 167.1 4.7 6.3e-48 162.6 3.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) Isochorismatase PF00857.15 EDN07968.1 - 1e-18 67.8 0.3 4.8e-18 65.7 0.2 1.8 1 1 0 1 1 1 1 Isochorismatase family Acyl-CoA_dh_1 PF00441.19 EDN07969.1 - 9.1e-17 61.5 0.5 4.6e-16 59.2 0.3 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDN07969.1 - 2.8e-05 23.5 0.6 0.00022 20.6 0.4 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AcylCoA_dehyd_C PF12186.3 EDN07969.1 - 0.0062 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase C terminal RVP PF00077.15 EDN07970.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EDN07970.1 - 0.14 12.7 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease p450 PF00067.17 EDN07971.1 - 5.9e-69 232.7 0.0 7.1e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ssu72 PF04722.8 EDN07972.1 - 7e-84 280.0 0.0 8.1e-84 279.8 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein SNF2_N PF00176.18 EDN07973.1 - 8.9e-53 179.0 0.0 1.4e-52 178.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EDN07973.1 - 5.4e-27 93.4 0.4 1.6e-26 91.9 0.2 1.9 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EDN07973.1 - 3.3e-13 49.3 0.0 6.4e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN07973.1 - 0.00026 20.8 0.1 0.0071 16.1 0.0 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit RNase_PH PF01138.16 EDN07974.1 - 2.1e-31 108.9 0.1 3.2e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Coiled PF05710.7 EDN07974.1 - 0.15 12.5 3.6 0.42 11.1 2.5 1.7 1 0 0 1 1 1 0 Coiled coil Pro_isomerase PF00160.16 EDN07975.1 - 4.8e-41 140.5 2.2 8.2e-41 139.7 1.5 1.3 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1840 PF08895.6 EDN07976.1 - 0.064 13.2 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) GIT_SHD PF08518.6 EDN07977.1 - 7.1e-18 63.6 2.6 4e-11 42.0 0.3 2.4 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT HMG-CoA_red PF00368.13 EDN07978.1 - 5.8e-71 239.1 1.4 6.9e-71 238.8 1.0 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Fungal_trans PF04082.13 EDN07980.1 - 1e-09 37.6 0.0 1.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN07980.1 - 2.2 8.2 5.3 0.22 11.4 0.4 1.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3_1 PF00018.23 EDN07981.1 - 5e-11 41.8 0.0 1.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDN07981.1 - 1.5e-10 40.5 0.0 3.2e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDN07981.1 - 8.6e-08 31.5 0.0 2.1e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF605 PF04652.11 EDN07981.1 - 0.088 12.1 10.2 0.14 11.4 7.1 1.4 1 0 0 1 1 1 0 Vta1 like ORC6 PF05460.8 EDN07981.1 - 0.32 10.0 6.5 0.46 9.5 4.5 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Anophelin PF10731.4 EDN07981.1 - 2.1 8.4 0.0 2.1 8.4 0.0 3.2 4 0 0 4 4 4 0 Thrombin inhibitor from mosquito Neisseria_TspB PF05616.8 EDN07981.1 - 5.9 5.1 12.2 8.8 4.5 8.5 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein ENTH PF01417.15 EDN07982.1 - 1.8e-47 160.2 0.4 4e-47 159.1 0.3 1.6 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EDN07982.1 - 7.3e-05 21.5 0.1 0.0001 21.0 0.1 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 EDN07982.1 - 0.066 12.8 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 VHS domain Transp_cyt_pur PF02133.10 EDN07983.1 - 1.8e-38 132.2 32.2 2.4e-38 131.8 22.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Phage_Coat_Gp8 PF05371.7 EDN07983.1 - 0.28 10.7 2.4 34 4.0 0.0 3.3 3 0 0 3 3 3 0 Phage major coat protein, Gp8 DUF1129 PF06570.6 EDN07983.1 - 1.6 7.9 5.4 0.36 10.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) RasGAP_C PF03836.10 EDN07984.1 - 3.3e-48 162.9 5.6 7.8e-48 161.7 3.9 1.7 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EDN07984.1 - 2.4e-39 135.0 0.1 6.8e-39 133.5 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EDN07984.1 - 4.3e-12 44.5 37.2 0.23 11.2 0.2 13.6 15 0 0 15 15 15 6 IQ calmodulin-binding motif CH PF00307.26 EDN07984.1 - 1.8e-10 40.8 0.0 4.6e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain IMPDH PF00478.20 EDN07985.1 - 2.1e-83 280.1 0.1 9e-44 149.7 0.0 2.0 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EDN07985.1 - 2.8e-09 36.6 0.0 1.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 CBS domain GATase PF00117.23 EDN07986.1 - 4.2e-15 55.6 0.0 5.7e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EDN07986.1 - 0.0019 17.7 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EDN07986.1 - 0.018 14.4 0.3 0.092 12.1 0.2 2.1 1 1 0 1 1 1 0 Peptidase C26 NUDIX PF00293.23 EDN07987.1 - 2.6e-15 56.2 0.0 1e-14 54.3 0.0 2.0 1 1 0 1 1 1 1 NUDIX domain Chromo PF00385.19 EDN07987.1 - 0.077 12.6 0.2 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_S21e PF01249.13 EDN07988.1 - 2.7e-42 142.5 0.1 3e-42 142.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e tRNA-synt_2d PF01409.15 EDN07989.1 - 1.7e-87 292.7 0.0 2.2e-87 292.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EDN07989.1 - 1.8e-05 23.7 0.4 0.00034 19.4 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EDN07989.1 - 0.00071 19.2 0.0 0.0013 18.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 EDN07989.1 - 0.043 12.8 0.2 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Histidyl-tRNA synthetase HAMP PF00672.20 EDN07992.1 - 3.6e-46 155.2 16.2 8.4e-10 38.6 0.2 6.9 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 EDN07992.1 - 1.4e-30 105.2 0.1 5.8e-30 103.2 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EDN07992.1 - 1.1e-26 92.9 1.5 6.7e-25 87.2 0.2 3.5 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 EDN07992.1 - 6.8e-17 61.2 5.0 2.8e-16 59.2 0.0 4.3 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain NAAA-beta PF15508.1 EDN07992.1 - 0.023 15.0 2.5 17 5.8 0.1 5.7 4 1 0 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase NOD PF06816.8 EDN07992.1 - 0.028 13.4 0.1 0.84 8.7 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein DUF2365 PF10157.4 EDN07992.1 - 0.085 12.7 17.7 5.8 6.7 0.0 6.9 7 2 0 7 7 7 0 Uncharacterized conserved protein (DUF2365) AAA_13 PF13166.1 EDN07992.1 - 0.13 10.6 24.4 0.28 9.5 0.9 4.1 1 1 1 4 4 4 0 AAA domain Las1 PF04031.8 EDN07992.1 - 0.29 10.7 4.1 11 5.7 0.1 4.6 6 0 0 6 6 6 0 Las1-like DUF2877 PF11392.3 EDN07992.1 - 4.8 7.4 12.8 7 6.9 0.4 4.8 2 2 2 4 4 4 0 Protein of unknown function (DUF2877) MFS_1 PF07690.11 EDN07994.1 - 6.5e-29 100.7 49.7 1.7e-23 82.9 29.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN07994.1 - 5.5e-11 41.7 38.1 1.5e-08 33.7 11.3 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EDN07996.1 - 9.5e-30 103.4 35.0 1.5e-18 66.6 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN07996.1 - 2.4e-20 72.5 18.2 8e-20 70.8 12.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.20 EDN07997.1 - 7.1e-69 231.8 0.0 1.1e-68 231.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN07997.1 - 7.1e-33 113.7 0.1 6.2e-31 107.4 0.1 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN07997.1 - 0.00038 19.5 0.3 0.57 9.0 0.0 2.6 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EDN07997.1 - 0.0046 16.3 0.9 0.009 15.3 0.6 1.4 1 0 0 1 1 1 1 RIO1 family Peptidase_S10 PF00450.17 EDN07998.1 - 6.5e-60 203.4 0.1 7.7e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Fungal_trans PF04082.13 EDN08000.1 - 1e-11 44.2 0.4 1.7e-11 43.5 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN08000.1 - 1.5e-06 28.0 8.7 3e-06 27.0 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDN08003.1 - 2.2e-19 69.3 0.2 9.3e-19 67.3 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN08003.1 - 2.2e-06 27.4 6.6 4.7e-06 26.3 4.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta_elim_lyase PF01212.16 EDN08004.1 - 2.6e-57 194.1 0.0 3.2e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase NIF PF03031.13 EDN08005.1 - 6.5e-39 133.1 0.1 9.3e-39 132.6 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase JAB PF01398.16 EDN08006.1 - 1.9e-18 66.2 0.0 3.7e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EDN08006.1 - 0.035 13.6 0.0 0.073 12.6 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.14 EDN08007.1 - 1.3e-46 159.3 0.1 1.5e-46 159.0 0.1 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Ribosomal_L14 PF00238.14 EDN08009.1 - 7.9e-33 112.8 0.0 8.8e-33 112.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Metallophos PF00149.23 EDN08010.1 - 0.00014 21.2 6.5 0.2 11.0 0.1 3.0 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase PH PF00169.24 EDN08011.1 - 4.1e-11 43.0 0.0 1.3e-10 41.3 0.0 1.9 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 EDN08011.1 - 7.3e-09 34.8 0.0 1.5e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDN08011.1 - 1.1e-08 34.4 0.1 2.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 EDN08011.1 - 2.8e-08 33.4 0.3 5e-08 32.6 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 EDN08011.1 - 1.2e-07 32.0 0.0 4e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 EDN08011.1 - 0.00013 21.3 0.1 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EDN08011.1 - 0.0031 17.6 0.2 0.0076 16.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.1 EDN08011.1 - 0.042 13.9 0.1 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain zf-MIZ PF02891.15 EDN08013.1 - 2.4e-10 39.7 0.1 5.8e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EDN08013.1 - 0.0047 16.4 0.5 0.019 14.4 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Nsp1_C PF05064.8 EDN08015.1 - 4.4e-42 142.4 3.2 4.4e-42 142.4 2.2 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EDN08015.1 - 0.0034 17.5 136.1 0.0098 16.1 32.5 4.7 1 1 2 3 3 2 2 Nucleoporin FG repeat region CENP-Q PF13094.1 EDN08015.1 - 0.0054 16.7 7.9 0.01 15.9 5.5 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF4200 PF13863.1 EDN08015.1 - 0.015 15.2 3.1 0.015 15.2 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) APG6 PF04111.7 EDN08015.1 - 0.051 12.6 9.4 0.077 12.0 6.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ParB PF08775.5 EDN08015.1 - 0.052 13.8 0.5 0.052 13.8 0.4 1.8 2 1 0 2 2 2 0 ParB family Macoilin PF09726.4 EDN08015.1 - 0.056 11.7 6.6 0.082 11.1 4.6 1.3 1 0 0 1 1 1 0 Transmembrane protein Baculo_PEP_C PF04513.7 EDN08015.1 - 0.12 12.1 4.2 0.22 11.3 2.5 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.2 EDN08015.1 - 0.18 11.1 14.4 0.29 10.4 8.9 1.9 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Spc7 PF08317.6 EDN08015.1 - 0.3 9.7 10.6 0.2 10.2 1.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.1 EDN08015.1 - 0.43 8.9 9.9 0.11 10.9 2.7 1.9 1 1 1 2 2 2 0 AAA domain Laminin_II PF06009.7 EDN08015.1 - 0.99 9.1 9.9 5.7 6.6 4.2 2.5 1 1 1 2 2 2 0 Laminin Domain II Syntaxin PF00804.20 EDN08015.1 - 1 9.5 7.2 11 6.2 5.0 2.2 1 1 0 1 1 1 0 Syntaxin IFT57 PF10498.4 EDN08015.1 - 1 8.0 12.4 6.5 5.3 8.4 1.9 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Tropomyosin_1 PF12718.2 EDN08015.1 - 1.7 8.4 11.2 0.29 10.9 4.9 1.7 1 1 0 1 1 1 0 Tropomyosin like Spectrin PF00435.16 EDN08015.1 - 1.9 8.7 9.4 0.64 10.3 2.8 2.5 1 1 1 2 2 2 0 Spectrin repeat IncA PF04156.9 EDN08015.1 - 2.5 7.6 14.1 5.2 6.6 9.6 1.6 1 1 0 1 1 1 0 IncA protein DUF342 PF03961.8 EDN08015.1 - 7.5 4.8 6.8 11 4.3 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 EDN08015.1 - 9.8 3.8 6.1 19 2.9 4.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family IATP PF04568.7 EDN08016.1 - 6e-20 71.1 0.9 7e-20 70.9 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Atg14 PF10186.4 EDN08016.1 - 0.0072 15.3 0.6 0.0077 15.2 0.4 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 BLOC1_2 PF10046.4 EDN08016.1 - 0.0089 16.1 0.7 0.012 15.7 0.5 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dad2 PF08654.5 EDN08016.1 - 0.01 15.8 1.3 0.014 15.4 0.9 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad2 NinG PF05766.7 EDN08016.1 - 0.011 15.5 0.8 0.013 15.2 0.5 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein HrpJ PF07201.6 EDN08016.1 - 0.012 15.6 1.7 0.017 15.1 1.2 1.3 1 0 0 1 1 1 0 HrpJ-like domain CENP-F_leu_zip PF10473.4 EDN08016.1 - 0.03 14.1 4.3 0.03 14.1 3.0 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0449 PF15136.1 EDN08016.1 - 0.13 12.5 2.0 0.18 12.0 1.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DivIC PF04977.10 EDN08016.1 - 0.24 10.8 1.8 0.37 10.3 1.3 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF1843 PF08898.5 EDN08016.1 - 0.3 11.1 3.7 0.73 9.9 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DUF883 PF05957.8 EDN08016.1 - 0.31 11.4 3.2 0.47 10.8 0.8 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) 14-3-3 PF00244.15 EDN08017.1 - 2.1e-115 383.7 8.4 2.4e-115 383.5 5.8 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EDN08017.1 - 0.042 13.3 3.4 2.3 7.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) Peptidase_M17_N PF02789.12 EDN08017.1 - 0.072 12.8 0.3 0.26 11.0 0.0 2.1 2 1 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain DUF885 PF05960.6 EDN08017.1 - 0.15 11.1 3.3 0.14 11.2 1.6 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF2205 PF10224.4 EDN08018.1 - 3.8e-28 96.8 1.6 6.7e-28 96.0 1.1 1.4 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Myosin_tail_1 PF01576.14 EDN08018.1 - 0.00027 18.8 3.9 0.00035 18.4 2.7 1.1 1 0 0 1 1 1 1 Myosin tail Macoilin PF09726.4 EDN08018.1 - 0.0015 16.8 5.2 0.0018 16.6 3.6 1.0 1 0 0 1 1 1 1 Transmembrane protein Prefoldin PF02996.12 EDN08018.1 - 0.0078 15.8 3.3 0.041 13.5 2.2 1.9 1 1 1 2 2 2 2 Prefoldin subunit DUF972 PF06156.8 EDN08018.1 - 0.0082 16.4 1.3 0.014 15.7 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF972) DUF4201 PF13870.1 EDN08018.1 - 0.0093 15.4 1.6 0.013 14.8 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.4 EDN08018.1 - 0.0093 15.8 2.1 0.017 14.9 1.4 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_32 PF13654.1 EDN08018.1 - 0.011 14.4 0.7 0.012 14.3 0.5 1.1 1 0 0 1 1 1 0 AAA domain ERM PF00769.14 EDN08018.1 - 0.013 15.1 3.0 0.019 14.4 2.1 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Tektin PF03148.9 EDN08018.1 - 0.013 14.0 2.0 0.02 13.4 1.4 1.2 1 0 0 1 1 1 0 Tektin family Rootletin PF15035.1 EDN08018.1 - 0.016 15.1 2.7 0.027 14.4 1.9 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Spectrin PF00435.16 EDN08018.1 - 0.02 15.1 1.0 0.033 14.4 0.7 1.3 1 0 0 1 1 1 0 Spectrin repeat DivIC PF04977.10 EDN08018.1 - 0.06 12.8 2.0 0.12 11.9 1.4 1.5 1 0 0 1 1 1 0 Septum formation initiator Sas10_Utp3 PF04000.10 EDN08018.1 - 0.072 13.3 0.5 0.21 11.7 0.1 1.8 2 0 0 2 2 2 0 Sas10/Utp3/C1D family ADIP PF11559.3 EDN08018.1 - 0.075 12.9 3.8 0.12 12.2 2.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 EDN08018.1 - 0.083 12.9 5.3 0.091 12.7 3.0 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit V_ATPase_I PF01496.14 EDN08018.1 - 0.085 10.7 0.5 0.084 10.7 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 EDN08018.1 - 0.09 12.5 0.7 0.14 11.9 0.5 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HALZ PF02183.13 EDN08018.1 - 0.14 11.9 5.3 2.5 7.8 0.1 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 EDN08018.1 - 0.22 10.6 3.5 0.081 12.0 0.3 1.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 EDN08018.1 - 0.28 10.7 4.6 0.13 11.8 1.2 1.7 2 0 0 2 2 2 0 IncA protein PP28 PF10252.4 EDN08018.1 - 0.92 9.5 6.0 0.29 11.1 1.6 1.9 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 MerR-DNA-bind PF09278.6 EDN08018.1 - 1 9.8 3.9 0.32 11.4 0.6 1.8 2 0 0 2 2 1 0 MerR, DNA binding DUF4140 PF13600.1 EDN08018.1 - 1.5 9.2 6.7 0.24 11.8 1.3 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlxA PF14282.1 EDN08018.1 - 7.6 6.5 9.4 0.25 11.3 0.7 2.2 2 0 0 2 2 2 0 FlxA-like protein Glyco_hydro_76 PF03663.9 EDN08020.1 - 1.1e-14 54.6 3.3 1.4e-14 54.2 1.7 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 RRM_1 PF00076.17 EDN08021.1 - 2.5e-07 30.2 0.3 1.5e-06 27.7 0.2 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN08021.1 - 1.1e-05 25.2 0.0 2.5e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN08021.1 - 7.7e-05 22.4 0.1 0.00084 19.1 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDN08021.1 - 0.019 14.7 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif Cutinase PF01083.17 EDN08022.1 - 2.2e-41 141.5 0.0 4.1e-41 140.6 0.0 1.4 2 0 0 2 2 2 1 Cutinase PE-PPE PF08237.6 EDN08022.1 - 0.00028 20.3 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Lipase_3 PF01764.20 EDN08022.1 - 0.003 17.1 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 EDN08022.1 - 0.0058 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EDN08022.1 - 0.0059 16.3 0.1 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_9 PF10081.4 EDN08022.1 - 0.037 12.7 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family VirJ PF06057.6 EDN08022.1 - 0.056 13.2 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Pes-10 PF07149.6 EDN08023.1 - 0.11 11.1 0.8 0.15 10.7 0.5 1.1 1 0 0 1 1 1 0 Pes-10 Alpha-amylase PF00128.19 EDN08024.1 - 6.8e-55 186.6 0.2 1e-54 186.1 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EDN08024.1 - 1.3e-22 79.6 0.0 2.7e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Bax1-I PF01027.15 EDN08025.1 - 1.3e-29 103.3 10.5 2e-29 102.6 7.3 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CGI-121 PF08617.5 EDN08026.1 - 2.5e-22 79.2 0.0 3.2e-16 59.4 0.0 2.1 1 1 1 2 2 2 2 Kinase binding protein CGI-121 Slx4 PF09494.5 EDN08027.1 - 6.2e-28 96.3 0.0 1.3e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 Slx4 endonuclease Zn_clus PF00172.13 EDN08028.1 - 0.00084 19.1 12.4 0.0016 18.3 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COPR5 PF15340.1 EDN08028.1 - 0.33 11.3 3.2 0.5 10.7 1.0 2.2 1 1 1 2 2 2 0 Cooperator of PRMT5 family Atg14 PF10186.4 EDN08028.1 - 2.2 7.1 22.0 0.064 12.2 8.8 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 EDN08028.1 - 6.2 4.5 7.3 0.3 8.8 1.3 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family cNMP_binding PF00027.24 EDN08029.1 - 3.6e-17 61.9 0.1 5.9e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EDN08029.1 - 4.3e-10 38.6 5.7 0.02 14.9 0.2 6.4 6 0 0 6 6 6 2 Leucine Rich repeat LRR_8 PF13855.1 EDN08029.1 - 2e-06 27.4 0.5 0.00061 19.4 0.3 3.8 2 1 2 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 EDN08029.1 - 2.1e-06 26.9 5.4 8.9 6.7 0.1 7.0 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_4 PF12799.2 EDN08029.1 - 0.001 18.6 0.0 0.037 13.6 0.0 3.4 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EDN08029.1 - 0.0029 17.5 12.5 27 5.5 0.1 6.6 7 0 0 7 7 7 0 Leucine rich repeat Ste50p-SAM PF09235.5 EDN08029.1 - 0.047 13.7 1.4 3.3 7.7 0.2 3.3 2 1 0 2 2 2 0 Ste50p, sterile alpha motif Kinesin PF00225.18 EDN08033.1 - 1.7e-116 388.5 0.0 2.6e-116 388.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA_33 PF13671.1 EDN08033.1 - 0.0089 15.9 0.0 0.048 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain PMSR PF01625.16 EDN08034.1 - 1.1e-57 194.2 0.0 1.4e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Pro_dh PF01619.13 EDN08035.1 - 6.7e-37 127.1 1.4 2.4e-35 122.0 1.0 2.5 1 1 0 1 1 1 1 Proline dehydrogenase B1 PF02246.10 EDN08035.1 - 0.021 14.6 0.8 0.048 13.5 0.3 1.7 2 0 0 2 2 2 0 Protein L b1 domain CCDC-167 PF15188.1 EDN08036.1 - 0.025 14.5 0.9 0.08 12.9 0.6 1.9 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Glyco_hydro_16 PF00722.16 EDN08037.1 - 6.8e-45 152.6 3.1 9.5e-45 152.1 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EDN08037.1 - 0.0096 15.8 13.4 0.02 14.8 9.3 1.4 1 0 0 1 1 1 1 Chitin recognition protein Alk_phosphatase PF00245.15 EDN08039.1 - 1.9e-98 329.9 0.0 2.3e-98 329.6 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase DUF498 PF04430.9 EDN08040.1 - 2e-25 88.4 0.0 3.9e-25 87.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) ABC_tran PF00005.22 EDN08041.1 - 5.2e-32 111.0 0.0 1.5e-31 109.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EDN08041.1 - 4e-16 59.2 6.3 1.7e-07 30.9 1.2 2.3 1 1 1 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EDN08041.1 - 1.9e-07 30.5 0.0 7e-06 25.4 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDN08041.1 - 4.8e-05 23.4 0.1 0.017 15.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN08041.1 - 0.0011 18.9 0.6 0.0048 16.9 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 EDN08041.1 - 0.0024 17.7 0.4 0.037 13.9 0.3 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EDN08041.1 - 0.0041 16.6 0.1 0.014 14.9 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EDN08041.1 - 0.012 15.7 0.4 0.11 12.6 0.1 2.4 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EDN08041.1 - 0.016 14.4 0.0 0.039 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EDN08041.1 - 0.072 12.8 0.1 0.96 9.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) WD40 PF00400.27 EDN08044.1 - 7.2e-25 85.9 10.2 9e-10 38.0 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EDN08044.1 - 0.00045 19.9 0.0 0.35 10.5 0.0 3.3 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A CAP_N PF01213.14 EDN08044.1 - 0.8 8.9 9.4 0.54 9.5 4.8 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal FYVE_2 PF02318.11 EDN08045.1 - 0.12 12.2 1.9 0.29 11.0 1.3 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger XLF PF09302.6 EDN08047.1 - 5.2e-10 39.3 0.0 5.5e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 XLF (XRCC4-like factor) Cactin_mid PF10312.4 EDN08048.1 - 1.7e-68 229.6 1.7 2.5e-68 229.1 1.1 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EDN08048.1 - 4e-55 184.7 6.8 6.9e-55 183.9 4.7 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Fork_head PF00250.13 EDN08049.1 - 3.5e-15 55.8 0.1 5.3e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Fork head domain Ribosomal_L34e PF01199.13 EDN08051.1 - 3.3e-37 126.5 3.3 4.6e-37 126.1 2.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e PDGF PF00341.12 EDN08051.1 - 0.084 12.9 0.1 0.084 12.9 0.1 1.7 2 1 0 2 2 2 0 PDGF/VEGF domain PROCN PF08083.6 EDN08052.1 - 9.3e-158 524.9 3.7 2.2e-157 523.7 2.5 1.6 1 1 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EDN08052.1 - 3e-126 419.3 2.2 5.4e-126 418.5 1.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EDN08052.1 - 4.5e-109 360.8 0.2 5.2e-64 214.4 0.0 2.6 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EDN08052.1 - 4.8e-78 260.0 1.9 1.3e-77 258.7 1.3 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EDN08052.1 - 1.7e-66 221.9 0.2 3.5e-66 220.9 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Hom_end_hint PF05203.11 EDN08052.1 - 1.4e-62 211.2 0.0 4.1e-59 199.8 0.0 3.4 2 1 0 2 2 2 1 Hom_end-associated Hint PROCT PF08084.6 EDN08052.1 - 1.3e-46 157.3 0.6 4.2e-46 155.7 0.1 2.2 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 EDN08052.1 - 2.4e-45 152.3 0.3 6.7e-45 150.8 0.2 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end PF05204.9 EDN08052.1 - 0.0001 22.1 0.0 0.00043 20.2 0.0 2.1 1 0 0 1 1 1 1 Homing endonuclease DUF3753 PF12575.3 EDN08052.1 - 0.16 11.8 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) OCD_Mu_crystall PF02423.10 EDN08052.1 - 0.37 9.5 1.6 0.65 8.6 1.1 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Myb_DNA-bind_6 PF13921.1 EDN08053.1 - 3e-13 49.6 0.0 2e-07 30.9 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN08053.1 - 3.7e-12 46.0 0.1 3.2e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain SelP_N PF04592.9 EDN08053.1 - 8 5.7 20.8 3.5 6.9 3.5 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region COX5B PF01215.14 EDN08054.1 - 3.9e-37 126.9 0.0 5.5e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 EDN08054.1 - 0.045 13.2 0.7 0.31 10.5 0.0 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Myb_DNA-binding PF00249.26 EDN08055.1 - 6.4e-14 51.7 5.2 2.1e-06 27.7 1.6 3.0 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN08055.1 - 4.2e-13 49.1 3.0 4.1e-06 26.8 0.2 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN08056.1 - 8.7e-08 32.1 0.4 0.00075 19.5 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN08056.1 - 0.0015 18.5 1.0 0.043 13.8 1.7 2.4 2 1 0 2 2 2 1 Myb-like DNA-binding domain Lac_bphage_repr PF06543.7 EDN08060.1 - 0.025 14.1 3.0 0.054 13.0 2.1 1.5 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor DUF3435 PF11917.3 EDN08061.1 - 7.2e-82 275.3 0.4 9.6e-82 274.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) eRF1_1 PF03463.10 EDN08062.1 - 5.5e-48 161.8 0.1 8.8e-48 161.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EDN08062.1 - 1.2e-18 67.7 0.0 7.3e-18 65.1 0.0 2.0 1 1 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EDN08062.1 - 8.7e-18 64.6 0.0 1.7e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 Aldo_ket_red PF00248.16 EDN08063.1 - 1.3e-42 145.5 0.0 1.1e-34 119.5 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Hepar_II_III PF07940.8 EDN08064.1 - 0.055 13.3 0.9 0.16 11.8 0.3 2.0 2 0 0 2 2 2 0 Heparinase II/III-like protein Daxx PF03344.10 EDN08064.1 - 0.14 10.5 13.6 0.18 10.2 9.4 1.1 1 0 0 1 1 1 0 Daxx Family Ribosomal_S19e PF01090.14 EDN08065.1 - 8.4e-57 190.5 0.3 9.5e-57 190.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Prim-Pol PF09250.6 EDN08065.1 - 0.029 14.3 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal DSPc PF00782.15 EDN08066.1 - 2e-09 37.1 0.0 1.1e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_6 PF12697.2 EDN08066.1 - 6.5e-08 32.7 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PTPlike_phytase PF14566.1 EDN08066.1 - 4.1e-05 23.6 0.0 7.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Ser_hydrolase PF06821.8 EDN08066.1 - 8.8e-05 22.1 0.0 0.00025 20.7 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_5 PF12695.2 EDN08066.1 - 0.00016 21.4 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EDN08066.1 - 0.023 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 EDN08066.1 - 0.033 13.7 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 EDN08066.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Y_phosphatase PF00102.22 EDN08066.1 - 0.1 11.9 0.0 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein-tyrosine phosphatase DUF900 PF05990.7 EDN08066.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) ILVD_EDD PF00920.16 EDN08067.1 - 5e-183 609.2 3.1 6e-183 608.9 2.1 1.0 1 0 0 1 1 1 1 Dehydratase family MFS_1 PF07690.11 EDN08068.1 - 6.7e-29 100.6 22.6 8.2e-29 100.4 15.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF596 PF04591.7 EDN08068.1 - 0.043 13.7 0.2 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF596 Paramecium_SA PF01508.11 EDN08069.1 - 7.9 6.7 15.0 0.23 11.6 4.7 2.3 2 0 0 2 2 2 0 Paramecium surface antigen domain Pex2_Pex12 PF04757.9 EDN08070.1 - 1.9e-39 135.4 1.1 2.6e-39 135.0 0.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EDN08070.1 - 0.0024 17.7 4.8 0.0024 17.7 3.3 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EDN08070.1 - 0.03 13.9 1.2 0.078 12.6 0.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN08070.1 - 0.031 14.2 8.4 0.13 12.3 3.1 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDN08070.1 - 0.035 13.8 2.8 0.26 11.0 1.9 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 EDN08070.1 - 0.59 10.0 6.8 10 6.0 2.5 2.6 2 1 0 2 2 2 0 Ring finger domain NEL PF14496.1 EDN08071.1 - 0.033 13.4 0.0 0.037 13.3 0.0 1.1 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting DUF905 PF06006.7 EDN08071.1 - 0.08 12.3 0.3 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) Ferritin_2 PF13668.1 EDN08071.1 - 0.083 12.8 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Ferritin-like domain APH PF01636.18 EDN08072.1 - 3e-11 43.4 0.0 1.6e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EDN08072.1 - 0.0097 15.0 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EDN08072.1 - 0.029 13.9 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EDN08072.1 - 0.069 11.7 0.0 0.095 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) APH_6_hur PF04655.9 EDN08072.1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase GBP PF02263.14 EDN08073.1 - 0.047 12.7 0.1 0.079 12.0 0.1 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Cellulase PF00150.13 EDN08074.1 - 3.4e-20 72.4 0.2 3.4e-20 72.4 0.1 1.3 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EDN08074.1 - 0.01 14.9 0.1 2.2 7.2 0.0 2.1 1 1 0 2 2 2 0 Beta-galactosidase GPI-anchored PF10342.4 EDN08077.1 - 1.2e-23 83.3 0.1 1.2e-23 83.3 0.1 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family USP8_interact PF08941.5 EDN08078.1 - 0.012 14.9 2.1 0.02 14.2 1.5 1.3 1 0 0 1 1 1 0 USP8 interacting TBPIP PF07106.8 EDN08078.1 - 1.3 8.5 10.3 0.82 9.2 0.3 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF16 PF01519.11 EDN08078.1 - 1.5 9.0 3.7 3.2 8.0 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 Tropomyosin_1 PF12718.2 EDN08078.1 - 1.5 8.6 14.6 2.6 7.9 6.5 2.4 1 1 1 2 2 2 0 Tropomyosin like CENP-F_leu_zip PF10473.4 EDN08078.1 - 2.4 8.0 14.9 1.4 8.7 4.6 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2413 PF10310.4 EDN08079.1 - 1.4e-145 485.5 0.0 1.6e-145 485.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) CMD PF02627.15 EDN08080.1 - 4e-08 32.9 0.1 1.4e-07 31.2 0.0 1.9 1 1 1 2 2 2 1 Carboxymuconolactone decarboxylase family zf-Mss51 PF13824.1 EDN08082.1 - 0.006 16.4 0.7 0.015 15.1 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 C1_1 PF00130.17 EDN08082.1 - 0.024 14.3 1.6 0.045 13.4 1.1 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PSD2 PF07624.6 EDN08082.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) DDE_1 PF03184.14 EDN08083.1 - 9.2e-51 172.0 0.0 2.1e-50 170.8 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN08083.1 - 7.4e-06 25.7 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease TFR_dimer PF04253.10 EDN08084.1 - 3.2e-19 68.7 0.1 5.5e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EDN08084.1 - 3e-16 59.6 0.3 6.9e-16 58.4 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 EDN08084.1 - 9.5e-08 31.6 0.0 1.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 EDN08084.1 - 0.029 13.6 0.3 0.056 12.6 0.0 1.5 2 0 0 2 2 2 0 Nicastrin MFS_1 PF07690.11 EDN08085.1 - 4e-35 121.1 39.3 6.6e-34 117.1 11.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN08085.1 - 1.4e-09 37.0 6.4 1.4e-09 37.0 4.4 2.9 2 2 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 EDN08085.1 - 3e-06 25.9 2.1 3e-06 25.9 1.4 2.6 3 0 0 3 3 3 1 MFS/sugar transport protein TRI12 PF06609.8 EDN08085.1 - 0.00036 18.8 0.7 0.00077 17.7 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 EDN08086.1 - 9.2e-55 185.9 0.0 3.3e-54 184.1 0.0 1.6 1 1 1 2 2 2 1 Cytochrome P450 DUF1582 PF07621.6 EDN08086.1 - 0.081 12.9 1.1 1.3 9.0 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1582) Fungal_trans PF04082.13 EDN08087.1 - 1.8e-14 53.2 0.7 2.9e-14 52.5 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DDE_Tnp_ISL3 PF01610.12 EDN08087.1 - 0.084 12.4 0.4 0.16 11.5 0.3 1.4 1 0 0 1 1 1 0 Transposase DUF726 PF05277.7 EDN08088.1 - 5.6e-128 426.6 3.2 7.8e-128 426.1 2.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) UPF0565 PF10561.4 EDN08088.1 - 0.085 11.7 1.3 0.12 11.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 Lipase_3 PF01764.20 EDN08088.1 - 0.1 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) RTC4 PF14474.1 EDN08089.1 - 1.6e-37 128.1 0.0 2.6e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain Tmemb_14 PF03647.8 EDN08090.1 - 1.6e-24 86.1 4.2 1.9e-24 85.8 2.9 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF1427 PF07235.6 EDN08090.1 - 0.23 11.5 1.4 0.54 10.3 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1427) DUF4131 PF13567.1 EDN08090.1 - 0.34 10.3 1.8 0.44 9.9 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DAD PF02109.11 EDN08091.1 - 1.1e-40 138.1 1.4 3.7e-39 133.2 1.0 2.0 1 1 0 1 1 1 1 DAD family DUF1180 PF06679.7 EDN08091.1 - 0.036 13.9 0.8 0.096 12.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) HA2 PF04408.18 EDN08092.1 - 6.5e-24 83.9 1.3 1.7e-23 82.5 0.0 2.5 4 0 0 4 4 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EDN08092.1 - 1.2e-23 83.0 0.0 1.1e-21 76.7 0.0 2.6 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EDN08092.1 - 9e-14 51.0 0.0 2.3e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN08092.1 - 7.9e-08 31.9 0.1 1.4e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDN08092.1 - 0.00033 20.7 0.1 0.00069 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EDN08092.1 - 0.0016 17.3 0.0 0.0037 16.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 EDN08092.1 - 0.0017 18.2 0.0 0.67 9.7 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.1 EDN08092.1 - 0.008 16.0 0.1 0.057 13.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 EDN08092.1 - 0.01 15.2 0.5 0.026 13.9 0.3 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DUF2075 PF09848.4 EDN08092.1 - 0.018 14.0 0.0 0.035 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EDN08092.1 - 0.02 14.0 0.1 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EDN08092.1 - 0.023 14.3 0.2 0.5 9.9 0.1 2.3 2 0 0 2 2 2 0 NACHT domain G-alpha PF00503.15 EDN08092.1 - 0.035 12.8 0.3 0.083 11.5 0.2 1.6 1 0 0 1 1 1 0 G-protein alpha subunit Flavi_DEAD PF07652.9 EDN08092.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain NB-ARC PF00931.17 EDN08092.1 - 0.1 11.4 0.0 0.23 10.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 EDN08092.1 - 0.16 11.4 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CBFD_NFYB_HMF PF00808.18 EDN08093.1 - 2.7e-13 49.7 0.2 4.5e-12 45.8 0.2 2.1 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sporozoite_P67 PF05642.6 EDN08093.1 - 0.17 9.6 1.6 0.18 9.5 1.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Fungal_trans PF04082.13 EDN08096.1 - 6.5e-05 21.9 0.3 0.00038 19.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain GCR1_C PF12550.3 EDN08097.1 - 6.5e-16 57.9 0.2 2.8e-15 55.9 0.0 2.3 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes DRY_EERY PF09750.4 EDN08097.1 - 0.24 11.5 3.4 0.46 10.5 1.8 1.8 1 1 0 1 1 1 0 Alternative splicing regulator Vasculin PF15337.1 EDN08099.1 - 0.054 13.9 0.2 0.15 12.5 0.2 1.7 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 dDENN PF03455.14 EDN08099.1 - 0.06 13.4 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 dDENN domain tRNA_Me_trans PF03054.11 EDN08100.1 - 0.1 11.1 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 tRNA methyl transferase AAA PF00004.24 EDN08101.1 - 2.5e-12 47.1 0.0 5.2e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN08101.1 - 3.2e-05 23.9 0.1 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDN08101.1 - 0.00095 19.3 0.0 0.0074 16.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDN08101.1 - 0.0022 18.8 0.0 0.01 16.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EDN08101.1 - 0.0082 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EDN08101.1 - 0.023 14.4 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EDN08101.1 - 0.092 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDN08101.1 - 0.097 12.9 0.0 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EDN08101.1 - 0.17 11.6 0.1 0.5 10.1 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Ank_2 PF12796.2 EDN08102.1 - 8.3e-44 147.8 3.3 6.9e-16 58.3 0.0 2.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EDN08102.1 - 1.3e-29 100.4 4.6 1.2e-11 43.8 0.0 4.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EDN08102.1 - 1.3e-19 69.7 0.4 3.5e-10 39.8 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN08102.1 - 1.4e-19 70.0 0.1 6.8e-06 26.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN08102.1 - 6.3e-19 66.1 0.6 7.9e-06 25.6 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat DDE_1 PF03184.14 EDN08103.1 - 2.9e-52 176.9 0.0 5e-52 176.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN08103.1 - 4.7e-11 42.3 0.0 9.4e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN08103.1 - 1.2e-08 34.3 0.1 2.9e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DUF3435 PF11917.3 EDN08104.1 - 3.6e-112 375.1 1.5 6.7e-111 370.9 0.6 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) DUF106 PF01956.11 EDN08105.1 - 0.19 11.2 1.5 0.26 10.7 1.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Dzip-like_N PF13815.1 EDN08105.1 - 0.54 10.0 10.6 0.36 10.6 5.2 2.2 2 1 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Pkinase PF00069.20 EDN08106.1 - 1.1e-09 37.8 0.1 2.1e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN08106.1 - 0.0016 18.1 0.1 0.0053 16.5 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN08106.1 - 0.014 14.4 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Aminotran_1_2 PF00155.16 EDN08107.1 - 3.8e-16 58.9 0.0 5e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EDN08107.1 - 0.00027 19.6 0.0 0.00091 17.8 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EDN08107.1 - 0.0029 16.7 0.0 0.019 14.0 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pkinase PF00069.20 EDN08108.1 - 3.3e-53 180.4 0.0 4.5e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN08108.1 - 2e-38 131.9 0.0 2.9e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN08108.1 - 1.7e-05 23.9 0.0 2.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN08108.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EDN08108.1 - 0.015 14.3 0.3 0.031 13.3 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EDN08108.1 - 0.052 12.8 0.1 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.4 EDN08108.1 - 0.18 11.0 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL ICAT PF06384.6 EDN08109.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT SR-25 PF10500.4 EDN08109.1 - 8.8 5.7 16.2 0.42 10.0 7.0 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 EDN08110.1 - 9.3e-62 208.5 0.0 1.4e-61 207.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN08110.1 - 1.7e-26 92.8 0.1 3.6e-26 91.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN08110.1 - 0.00099 18.1 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EDN08110.1 - 0.019 14.3 0.0 0.056 12.7 0.0 1.8 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EDN08110.1 - 0.021 14.5 0.1 0.067 12.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EDN08110.1 - 0.021 13.8 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.21 EDN08112.1 - 1.5e-20 73.0 8.1 4.4e-20 71.5 5.6 1.6 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDN08112.1 - 9e-05 22.3 0.7 0.00017 21.4 0.4 1.5 1 1 0 1 1 1 1 RWD domain Gryzun PF07919.7 EDN08112.1 - 0.0004 18.8 0.2 0.00052 18.4 0.2 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Prok-E2_B PF14461.1 EDN08112.1 - 0.00056 19.6 0.0 0.0024 17.6 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic E2 family B Mucin PF01456.12 EDN08112.1 - 0.0017 18.1 18.2 0.0023 17.7 12.6 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein BatD PF13584.1 EDN08112.1 - 0.028 13.0 0.6 0.036 12.6 0.4 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF2931 PF11153.3 EDN08112.1 - 0.033 13.5 0.1 0.044 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) Med3 PF11593.3 EDN08112.1 - 0.038 13.2 6.2 0.039 13.1 4.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF605 PF04652.11 EDN08112.1 - 0.11 11.9 4.7 0.1 12.0 3.2 1.1 1 0 0 1 1 1 0 Vta1 like SSP160 PF06933.6 EDN08112.1 - 0.24 9.3 11.5 0.27 9.1 8.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PRCC PF10253.4 EDN08112.1 - 0.31 11.7 2.1 0.38 11.4 1.4 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Lamp PF01299.12 EDN08112.1 - 0.48 9.5 10.6 0.7 8.9 7.3 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DUF515 PF04415.7 EDN08112.1 - 1.5 6.9 3.6 2.1 6.5 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) AflR PF08493.5 EDN08112.1 - 3.5 6.5 15.8 4.8 6.1 10.9 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein Complex1_49kDa PF00346.14 EDN08113.1 - 1.4e-134 447.3 0.0 1.7e-134 447.0 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit RNA_pol_A_bac PF01000.21 EDN08114.1 - 3.1e-27 94.9 0.0 5.6e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EDN08114.1 - 3.5e-12 45.2 0.0 4.6e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.16 EDN08115.1 - 8.2e-36 122.8 0.1 2.4e-35 121.3 0.0 1.8 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EDN08115.1 - 1.7e-24 85.1 0.9 3e-24 84.3 0.6 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 EDN08115.1 - 5.3e-24 83.7 0.1 9.4e-24 82.9 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 EDN08115.1 - 6.3e-14 51.0 2.1 6.3e-14 51.0 1.5 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 EDN08115.1 - 0.00072 19.1 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Ecm33 PF12454.3 EDN08115.1 - 0.043 13.6 2.3 0.091 12.6 1.6 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Telomere_reg-2 PF10193.4 EDN08116.1 - 2.2e-32 111.6 0.0 5.2e-32 110.4 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein Sec1 PF00995.18 EDN08117.1 - 4.8e-133 444.7 0.0 5.4e-133 444.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family zf-met PF12874.2 EDN08119.1 - 6.2e-06 26.2 1.5 1.8e-05 24.7 1.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EDN08119.1 - 1.5e-05 25.0 8.7 0.035 14.4 0.6 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EDN08119.1 - 1.8e-05 24.7 4.5 1.8e-05 24.7 3.1 2.2 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EDN08119.1 - 0.00011 22.1 2.1 0.00011 22.1 1.4 2.4 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EDN08119.1 - 0.00019 21.5 2.3 0.00019 21.5 1.6 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDN08119.1 - 0.0015 18.3 1.5 0.0038 17.0 1.1 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-BED PF02892.10 EDN08119.1 - 0.2 11.4 4.0 0.4 10.4 2.8 1.5 1 0 0 1 1 1 0 BED zinc finger Zip PF02535.17 EDN08119.1 - 0.2 10.5 0.4 0.19 10.7 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 EDN08119.1 - 2.4 6.9 18.4 3.5 6.3 12.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SelP_N PF04592.9 EDN08119.1 - 7.8 5.7 13.4 0.4 10.0 5.3 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region SF3b1 PF08920.5 EDN08121.1 - 1.4e-43 148.4 8.6 4.5e-43 146.7 0.4 2.4 1 1 1 2 2 2 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EDN08121.1 - 4.6e-15 55.6 4.5 0.01 16.0 0.0 7.3 7 1 1 8 8 8 5 HEAT repeats HEAT_EZ PF13513.1 EDN08121.1 - 7.1e-10 39.0 2.2 0.52 10.8 0.0 7.2 6 1 1 7 7 7 2 HEAT-like repeat HEAT PF02985.17 EDN08121.1 - 1.7e-09 36.9 12.2 0.84 9.8 0.1 9.2 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EDN08121.1 - 2.7e-05 24.4 0.0 1.3 9.4 0.0 5.0 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.7 EDN08121.1 - 0.0058 15.9 0.6 5.5 6.2 0.0 3.8 4 0 0 4 4 4 1 NUC173 domain CLASP_N PF12348.3 EDN08121.1 - 0.008 15.5 0.4 1 8.6 0.0 3.5 4 0 0 4 4 4 1 CLASP N terminal CRM1_C PF08767.6 EDN08121.1 - 0.19 10.5 0.4 0.75 8.6 0.1 2.0 2 0 0 2 2 2 0 CRM1 C terminal Methyltransf_11 PF08241.7 EDN08122.1 - 0.054 13.9 0.0 0.18 12.3 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain SAP PF02037.22 EDN08123.1 - 2.7e-12 45.8 1.0 1.5e-11 43.4 0.1 2.3 2 0 0 2 2 2 1 SAP domain Arr-ms PF12120.3 EDN08123.1 - 0.012 15.5 0.6 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Rifampin ADP-ribosyl transferase zf-Tim10_DDP PF02953.10 EDN08124.1 - 0.86 8.9 6.6 0.068 12.4 1.0 1.8 3 0 0 3 3 3 0 Tim10/DDP family zinc finger SSrecog PF03531.9 EDN08125.1 - 2.3e-67 226.5 0.2 2.7e-66 223.1 0.2 2.2 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EDN08125.1 - 1.6e-21 76.0 1.4 1e-20 73.5 0.1 2.6 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Glyco_hydro_76 PF03663.9 EDN08126.1 - 1.6e-36 126.4 0.7 1.6e-36 126.4 0.5 1.9 1 1 1 2 2 2 1 Glycosyl hydrolase family 76 Pro_CA PF00484.14 EDN08127.1 - 1e-48 165.2 0.0 1.9e-48 164.3 0.0 1.5 1 0 0 1 1 1 1 Carbonic anhydrase DUF3435 PF11917.3 EDN08127.1 - 2.3e-07 29.8 2.6 0.0024 16.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) ClpB_D2-small PF10431.4 EDN08128.1 - 0.094 12.6 0.0 6 6.8 0.0 2.4 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein Kdo PF06293.9 EDN08129.1 - 0.00029 19.9 0.1 0.00056 19.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EDN08129.1 - 0.014 14.7 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EDN08129.1 - 0.017 14.6 0.1 0.049 13.2 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.18 EDN08129.1 - 0.033 13.9 0.2 0.033 13.9 0.1 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family HlyD PF00529.15 EDN08129.1 - 4.5 6.4 9.8 7.1 5.8 6.8 1.2 1 0 0 1 1 1 0 HlyD family secretion protein RVT_2 PF07727.9 EDN08130.1 - 1.2e-58 197.9 0.0 9.2e-58 195.1 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN08130.1 - 4.2e-14 52.6 0.0 1.4e-13 50.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN08130.1 - 7.2e-08 31.9 0.0 2.2e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 EDN08130.1 - 1.4 9.0 5.5 2.9 7.9 3.8 1.6 1 0 0 1 1 1 0 Zinc knuckle BCS1_N PF08740.6 EDN08131.1 - 1e-22 80.6 0.2 2.5e-22 79.4 0.1 1.6 1 1 1 2 2 2 1 BCS1 N terminal AAA PF00004.24 EDN08131.1 - 2.2e-19 69.9 0.0 1.2e-18 67.5 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN08131.1 - 0.00018 21.5 0.1 0.00035 20.6 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EDN08131.1 - 0.0065 17.2 0.0 0.024 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN08131.1 - 0.0093 15.3 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDN08131.1 - 0.037 13.7 0.1 0.12 12.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EDN08131.1 - 0.051 12.6 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 EDN08131.1 - 0.053 13.6 0.0 0.16 12.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 EDN08131.1 - 0.059 12.2 0.0 0.45 9.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 EDN08131.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EDN08131.1 - 0.073 12.9 0.0 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.12 EDN08131.1 - 0.087 11.4 0.0 0.15 10.6 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase RuvB_N PF05496.7 EDN08131.1 - 0.089 11.8 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EDN08131.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain 7TMR-DISM_7TM PF07695.6 EDN08132.1 - 0.0089 15.7 2.4 0.0094 15.6 1.7 1.1 1 0 0 1 1 1 1 7TM diverse intracellular signalling Rnf-Nqr PF02508.9 EDN08132.1 - 0.087 12.4 0.9 0.14 11.7 0.5 1.4 1 1 0 1 1 1 0 Rnf-Nqr subunit, membrane protein Mur_ligase_M PF08245.7 EDN08134.1 - 1.1e-07 32.1 0.0 2.8e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain DUF2383 PF09537.5 EDN08136.1 - 0.015 15.5 0.1 0.038 14.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) zf-C2H2_4 PF13894.1 EDN08136.1 - 0.029 14.6 15.7 0.029 14.6 0.3 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN08136.1 - 0.042 14.1 11.5 0.56 10.6 1.6 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Ferritin-like PF12902.2 EDN08136.1 - 0.063 12.8 0.2 0.14 11.7 0.1 1.7 1 1 0 1 1 1 0 Ferritin-like DUF1273 PF06908.6 EDN08136.1 - 0.13 11.9 0.2 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) RVT_1 PF00078.22 EDN08137.1 - 4.5e-29 101.3 0.0 6.3e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF963 PF06131.6 EDN08138.1 - 0.067 12.4 1.6 0.25 10.6 0.4 2.0 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DUF3723 PF12520.3 EDN08139.1 - 4.4e-164 546.7 0.2 5.6e-164 546.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) 3HCDH_N PF02737.13 EDN08139.1 - 0.15 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3435 PF11917.3 EDN08140.1 - 1.5e-26 93.0 0.0 1.1e-25 90.2 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3435) Rax2 PF12768.2 EDN08142.1 - 2.2e-96 322.3 0.2 2.2e-91 305.9 0.0 4.3 4 2 1 5 5 5 2 Cortical protein marker for cell polarity Kelch_3 PF13415.1 EDN08142.1 - 0.08 13.1 4.9 11 6.3 0.0 5.4 6 0 0 6 6 6 0 Galactose oxidase, central domain OGG_N PF07934.7 EDN08144.1 - 5.8e-38 129.4 0.0 1.2e-37 128.4 0.0 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EDN08144.1 - 5.8e-18 65.1 0.0 1.1e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein RRM_1 PF00076.17 EDN08145.1 - 3e-36 122.8 0.6 2.4e-14 52.7 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN08145.1 - 1.5e-23 82.4 0.1 1.3e-08 34.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN08145.1 - 6.9e-16 57.8 0.2 5.8e-07 29.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EDN08145.1 - 8.7 4.6 17.3 11 4.2 12.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3435 PF11917.3 EDN08146.1 - 1.8e-16 59.8 0.1 3.6e-13 49.0 1.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) APH PF01636.18 EDN08148.1 - 1.7e-11 44.3 0.0 1.2e-09 38.2 0.0 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EDN08148.1 - 0.0014 17.8 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Dicty_CAR PF05462.6 EDN08150.1 - 0.00017 20.5 6.3 0.00021 20.2 4.3 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 EDN08150.1 - 0.00074 18.6 11.0 0.001 18.2 7.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Chromate_transp PF02417.10 EDN08151.1 - 2e-53 180.4 29.2 4.2e-27 94.8 10.9 2.3 2 0 0 2 2 2 2 Chromate transporter Ribosomal_S13_N PF08069.7 EDN08152.1 - 3.2e-30 103.7 0.1 5.9e-30 102.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EDN08152.1 - 3.1e-22 78.1 0.1 5.6e-22 77.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EDN08152.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain VRR_NUC PF08774.6 EDN08153.1 - 4.6e-18 65.0 0.0 1.1e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain SH3_1 PF00018.23 EDN08153.1 - 0.033 13.5 0.1 0.084 12.2 0.1 1.7 1 0 0 1 1 1 0 SH3 domain RRM_1 PF00076.17 EDN08154.1 - 7e-21 73.6 0.0 1.1e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN08154.1 - 1.5e-15 56.9 0.0 2.4e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN08154.1 - 1.8e-11 43.7 0.0 2.7e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-HC5HC2H_2 PF13832.1 EDN08155.1 - 3.9e-33 113.7 5.4 3.9e-33 113.7 3.8 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EDN08155.1 - 9.2e-28 96.2 2.7 9.2e-28 96.2 1.9 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EDN08155.1 - 6.1e-25 88.3 0.0 1.6e-24 86.9 0.0 1.8 1 0 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.1 EDN08155.1 - 5.3e-14 51.2 3.2 5.3e-14 51.2 2.2 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EDN08155.1 - 1.6e-08 34.0 24.7 5.8e-08 32.3 6.8 2.6 2 0 0 2 2 2 2 PHD-finger Myb_DNA-bind_6 PF13921.1 EDN08157.1 - 3.7e-10 39.7 0.7 1.1e-09 38.2 0.2 2.0 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN08157.1 - 0.019 15.0 0.0 0.077 13.0 0.0 2.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain Peptidase_M22 PF00814.20 EDN08158.1 - 3.7e-47 161.0 0.0 3.4e-41 141.5 0.0 3.7 2 1 0 2 2 2 2 Glycoprotease family YycC PF14174.1 EDN08158.1 - 0.0032 17.0 0.8 0.0052 16.4 0.0 1.8 2 0 0 2 2 2 1 YycC-like protein DUF508 PF04370.7 EDN08158.1 - 0.051 13.2 2.5 0.099 12.2 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Pol_alpha_B_N PF08418.5 EDN08159.1 - 2.1 7.8 7.6 2.7 7.4 5.3 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal EF-hand_1 PF00036.27 EDN08160.1 - 5.7e-15 53.4 1.2 7.2e-07 28.0 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EDN08160.1 - 1.1e-13 49.7 0.8 8.2e-07 28.3 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EDN08160.1 - 1.3e-11 43.8 0.9 0.012 15.2 0.1 4.2 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_7 PF13499.1 EDN08160.1 - 1.1e-10 41.4 4.1 1.6e-05 24.9 0.2 3.4 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EDN08160.1 - 2.3e-08 33.0 0.2 6.4e-06 25.2 0.1 3.2 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 EDN08160.1 - 0.0045 16.8 0.0 14 5.6 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 EDN08160.1 - 0.094 12.4 0.0 0.43 10.3 0.0 2.0 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Mito_carr PF00153.22 EDN08161.1 - 3.3e-06 26.7 0.0 4.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein MMR_HSR1 PF01926.18 EDN08162.1 - 0.00056 19.8 0.0 0.00095 19.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EDN08162.1 - 0.059 12.0 0.0 0.15 10.6 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit DUF1515 PF07439.6 EDN08162.1 - 0.074 12.8 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) ABC_tran PF00005.22 EDN08162.1 - 0.088 13.1 0.5 0.21 11.9 0.1 1.7 2 0 0 2 2 2 0 ABC transporter DUF87 PF01935.12 EDN08162.1 - 0.089 12.5 0.9 0.85 9.3 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function DUF87 AAA_17 PF13207.1 EDN08162.1 - 0.12 13.2 1.8 0.26 12.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF605 PF04652.11 EDN08162.1 - 0.82 8.9 3.8 1 8.6 2.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF572 PF04502.8 EDN08163.1 - 0.0039 16.4 0.2 0.0047 16.2 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) CCDC32 PF14989.1 EDN08163.1 - 0.029 14.2 0.6 0.05 13.4 0.4 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing 32 Peptidase_C50 PF03568.12 EDN08164.1 - 2.4e-117 391.8 0.0 4.1e-117 391.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 EDN08164.1 - 0.001 18.9 1.3 1.8 8.5 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat CHAT PF12770.2 EDN08164.1 - 0.0026 16.9 0.0 0.047 12.8 0.0 2.3 2 0 0 2 2 2 1 CHAT domain TPR_19 PF14559.1 EDN08164.1 - 0.062 13.6 0.3 9.5 6.6 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Esterase PF00756.15 EDN08165.1 - 5.3e-51 173.4 0.0 6.6e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 EDN08165.1 - 9.5e-06 25.0 0.0 7.5e-05 22.0 0.0 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EDN08165.1 - 1.1e-05 25.2 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN08165.1 - 2.8e-05 24.1 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDN08165.1 - 4.8e-05 22.6 0.1 8.5e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EDN08165.1 - 8.6e-05 22.1 0.0 0.00034 20.2 0.0 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EDN08165.1 - 0.0089 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase2 PF12740.2 EDN08165.1 - 0.014 14.2 0.0 0.031 13.1 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 EDN08165.1 - 0.026 14.0 0.0 0.19 11.2 0.0 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EDN08165.1 - 0.036 13.6 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein AXE1 PF05448.7 EDN08165.1 - 0.07 11.6 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EDN08165.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Xpo1 PF08389.7 EDN08166.1 - 1.8e-40 138.2 5.0 7e-40 136.3 0.2 3.3 4 0 0 4 4 4 1 Exportin 1-like protein DUF445 PF04286.7 EDN08166.1 - 0.085 12.3 2.7 4.5 6.7 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF445) HEAT PF02985.17 EDN08166.1 - 0.15 12.2 0.2 97 3.4 0.0 4.6 4 1 1 5 5 5 0 HEAT repeat TipAS PF07739.8 EDN08166.1 - 0.4 11.0 3.3 4.6 7.5 0.0 3.8 4 0 0 4 4 4 0 TipAS antibiotic-recognition domain FGGY_C PF02782.11 EDN08167.1 - 4.2e-31 108.1 0.0 1.6e-30 106.2 0.0 1.9 2 1 1 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EDN08167.1 - 1.4e-10 40.9 0.0 4.7e-05 22.8 0.0 3.0 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.16 EDN08168.1 - 9.8e-58 195.4 0.6 1.1e-57 195.2 0.4 1.0 1 0 0 1 1 1 1 Cation efflux family TrkH PF02386.11 EDN08168.1 - 0.016 13.7 0.0 0.027 13.0 0.0 1.2 1 0 0 1 1 1 0 Cation transport protein SIR2 PF02146.12 EDN08169.1 - 2.7e-31 108.6 0.0 5.2e-31 107.7 0.0 1.5 1 1 0 1 1 1 1 Sir2 family Pkinase PF00069.20 EDN08170.1 - 3.7e-76 255.7 0.0 4.5e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN08170.1 - 1.9e-37 128.7 0.0 2.7e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN08170.1 - 9e-05 21.5 0.2 0.00091 18.2 0.0 2.4 1 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 EDN08170.1 - 0.069 12.1 1.2 0.11 11.5 0.1 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN08170.1 - 0.1 12.3 3.9 0.061 13.0 0.5 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family TPR_11 PF13414.1 EDN08171.1 - 3.9e-06 26.4 9.8 0.015 14.9 0.1 4.5 4 1 0 4 4 4 2 TPR repeat TPR_17 PF13431.1 EDN08171.1 - 0.0022 18.0 1.1 1.5 9.2 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDN08171.1 - 0.35 11.6 10.6 1.1 10.0 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDN08171.1 - 2.7 8.8 9.8 2.6 8.9 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat NTF2 PF02136.15 EDN08173.1 - 1.2e-24 86.9 0.2 2.2e-24 86.0 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EDN08173.1 - 4e-06 26.3 0.1 8e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN08173.1 - 9.5e-05 22.3 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN08173.1 - 0.00017 21.3 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDN08173.1 - 0.021 14.6 0.1 0.083 12.7 0.0 2.0 1 0 0 1 1 1 0 RNA binding motif DDE_1 PF03184.14 EDN08174.1 - 4.7e-06 25.8 0.1 3.4e-05 23.0 0.1 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN08174.1 - 0.0072 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DUF1980 PF09323.5 EDN08174.1 - 0.011 15.5 0.9 0.017 14.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) NTPase_1 PF03266.10 EDN08174.1 - 0.013 15.1 0.1 0.018 14.7 0.1 1.2 1 0 0 1 1 1 0 NTPase HSP90 PF00183.13 EDN08176.1 - 1.3e-257 855.4 34.7 1.6e-257 855.1 24.0 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EDN08176.1 - 9.7e-13 47.9 0.3 9.7e-13 47.9 0.2 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDN08176.1 - 1.4e-11 44.0 0.0 2.6e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 EDN08176.1 - 0.073 12.8 2.3 0.14 11.9 0.1 2.6 3 0 0 3 3 3 0 Tumour suppressor protein DUF1676 PF07898.8 EDN08176.1 - 0.11 12.7 0.2 0.11 12.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Septin PF00735.13 EDN08177.1 - 1e-13 50.9 0.0 8.1e-10 38.1 0.0 2.3 2 0 0 2 2 2 2 Septin Miro PF08477.8 EDN08177.1 - 0.0051 17.3 0.0 0.013 15.9 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EDN08177.1 - 0.0074 16.2 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EDN08177.1 - 0.0074 15.4 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 EDN08177.1 - 0.013 15.7 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA PF00004.24 EDN08177.1 - 0.02 15.0 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EDN08177.1 - 0.03 13.5 0.1 0.1 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EDN08177.1 - 0.036 13.5 0.1 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EDN08177.1 - 0.043 12.9 0.2 1.6 7.7 0.1 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF815 PF05673.8 EDN08177.1 - 0.058 12.3 0.1 0.099 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PRK PF00485.13 EDN08177.1 - 0.072 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 EDN08177.1 - 0.073 12.7 0.2 0.24 11.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 EDN08177.1 - 0.082 12.0 0.0 0.3 10.2 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EDN08177.1 - 0.098 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EDN08177.1 - 0.1 12.1 0.0 0.31 10.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 EDN08177.1 - 0.13 10.9 0.1 0.3 9.7 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit DUF3435 PF11917.3 EDN08178.1 - 4.3e-45 154.1 3.2 4.3e-45 154.1 2.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) RNA_pol_Rpb5_N PF03871.9 EDN08178.1 - 0.029 14.7 1.8 0.067 13.5 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb5, N-terminal domain BTB PF00651.26 EDN08179.1 - 4.1e-05 23.5 0.1 0.00046 20.1 0.0 2.2 2 1 0 2 2 2 1 BTB/POZ domain DUF1338 PF07063.8 EDN08180.1 - 0.014 14.4 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) Dicty_REP PF05086.7 EDN08180.1 - 0.84 7.3 1.0 1.2 6.7 0.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AAA PF00004.24 EDN08181.1 - 1.1e-13 51.4 0.3 1.5e-06 28.3 0.0 2.5 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN08181.1 - 1.6e-06 28.2 0.6 7.6e-05 22.7 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain AAA_17 PF13207.1 EDN08181.1 - 3.7e-06 27.7 0.0 1.5e-05 25.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDN08181.1 - 0.0002 21.5 0.2 0.0029 17.7 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 EDN08181.1 - 0.00024 21.4 0.0 0.00092 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EDN08181.1 - 0.0019 18.0 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 EDN08181.1 - 0.0028 17.3 0.0 0.0066 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EDN08181.1 - 0.005 16.5 0.0 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EDN08181.1 - 0.012 15.4 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EDN08181.1 - 0.032 13.3 0.0 0.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RuvB_N PF05496.7 EDN08181.1 - 0.037 13.0 0.1 0.088 11.8 0.0 1.5 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Ribosomal_60s PF00428.14 EDN08181.1 - 0.052 13.9 0.0 2.6 8.5 0.0 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein RNA_helicase PF00910.17 EDN08181.1 - 0.059 13.5 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EDN08181.1 - 0.087 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 EDN08181.1 - 0.13 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF2559 PF10832.3 EDN08184.1 - 0.0092 15.7 0.3 0.028 14.2 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2559) DUF2011 PF09428.5 EDN08184.1 - 0.014 15.2 0.8 0.022 14.6 0.5 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) HlyD PF00529.15 EDN08184.1 - 0.035 13.3 0.4 0.041 13.1 0.3 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DivIC PF04977.10 EDN08184.1 - 0.05 13.0 7.5 0.25 10.8 1.2 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF3505 PF12013.3 EDN08184.1 - 0.052 13.7 0.2 0.094 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) Syntaxin-6_N PF09177.6 EDN08184.1 - 0.067 13.5 1.3 0.11 12.8 0.9 1.3 1 0 0 1 1 1 0 Syntaxin 6, N-terminal HLH PF00010.21 EDN08185.1 - 1.8e-14 53.1 0.1 3.7e-14 52.1 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF904 PF06005.7 EDN08185.1 - 0.14 12.5 2.0 0.15 12.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Leu_zip PF15294.1 EDN08185.1 - 0.37 9.8 2.9 0.62 9.1 2.0 1.2 1 0 0 1 1 1 0 Leucine zipper AAT PF03417.11 EDN08187.1 - 1.9e-08 34.0 0.0 3e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DDE_1 PF03184.14 EDN08188.1 - 1.8e-36 125.3 0.0 3.2e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN08188.1 - 1.8e-05 24.4 0.0 5.7e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN08188.1 - 0.0054 16.2 0.6 0.0054 16.2 0.4 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain TraG_N PF07916.6 EDN08188.1 - 0.73 8.2 3.6 1.1 7.6 2.5 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF2229 PF09989.4 EDN08188.1 - 4.1 6.8 8.7 37 3.6 6.0 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Borrelia_P83 PF05262.6 EDN08188.1 - 9.2 4.4 22.6 15 3.7 15.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SpoIIE PF07228.7 EDN08190.1 - 4.9e-05 23.1 0.7 0.00049 19.8 0.5 2.5 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EDN08190.1 - 0.0018 17.7 0.1 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EDN08190.1 - 0.015 14.7 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein phosphatase 2C WD40 PF00400.27 EDN08191.1 - 1.1e-27 94.7 3.8 5.3e-08 32.4 0.1 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 EDN08191.1 - 3.9e-05 22.0 3.4 0.001 17.3 0.1 2.7 2 1 0 2 2 2 2 Nucleoporin Nup120/160 DUF4241 PF14025.1 EDN08191.1 - 0.0085 15.8 0.1 0.019 14.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4241) RRN3 PF05327.6 EDN08193.1 - 1.1e-123 413.3 1.5 8.1e-85 285.0 0.0 3.9 1 1 3 4 4 4 2 RNA polymerase I specific transcription initiation factor RRN3 RecO_C PF02565.10 EDN08193.1 - 0.023 14.5 0.0 0.49 10.2 0.0 2.6 3 0 0 3 3 3 0 Recombination protein O C terminal U79_P34 PF03064.11 EDN08193.1 - 0.87 9.0 8.0 13 5.1 0.0 2.2 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Abhydrolase_3 PF07859.8 EDN08194.1 - 0.057 12.9 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold tRNA-synt_2 PF00152.15 EDN08195.1 - 1.3e-72 244.3 0.1 2e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EDN08195.1 - 4.8e-17 61.7 0.0 7e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EDN08195.1 - 1.5e-06 27.9 0.8 0.00015 21.5 0.4 2.5 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EDN08195.1 - 0.00066 18.9 0.8 0.93 8.6 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) P34-Arc PF04045.9 EDN08196.1 - 3.9e-105 350.5 0.0 4.7e-105 350.2 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EDN08196.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) WD40 PF00400.27 EDN08197.1 - 3.2e-72 236.0 24.8 7e-10 38.4 0.1 11.2 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 EDN08197.1 - 5.7e-22 77.7 0.1 1.1e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EDN08197.1 - 6.3e-05 21.3 4.6 0.013 13.7 0.0 4.7 4 2 1 5 5 5 1 Nucleoporin Nup120/160 DUF3312 PF11768.3 EDN08197.1 - 0.0082 14.4 0.1 0.19 9.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) CDtoxinA PF03498.9 EDN08197.1 - 0.012 14.9 0.1 1.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Cytolethal distending toxin A/C family Nucleoporin_N PF08801.6 EDN08197.1 - 0.061 12.0 8.7 0.18 10.5 0.1 4.4 2 2 1 4 4 4 0 Nup133 N terminal like WLM PF08325.5 EDN08198.1 - 3.6e-58 196.5 0.0 6.3e-58 195.7 0.0 1.4 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EDN08198.1 - 0.00017 20.6 21.8 0.00058 18.9 2.6 3.1 2 1 0 3 3 3 3 Zn-finger in Ran binding protein and others DUF45 PF01863.12 EDN08198.1 - 0.0017 18.1 1.7 0.0017 18.1 1.2 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 DZR PF12773.2 EDN08198.1 - 0.0021 17.8 7.0 0.23 11.3 0.4 2.4 2 0 0 2 2 2 2 Double zinc ribbon SprT-like PF10263.4 EDN08198.1 - 0.25 10.9 10.2 0.027 14.1 1.1 2.8 2 2 0 2 2 2 0 SprT-like family zf-Sec23_Sec24 PF04810.10 EDN08198.1 - 0.41 10.2 8.9 0.42 10.2 0.0 3.2 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger TrbC PF04956.8 EDN08199.1 - 0.032 14.2 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 TrbC/VIRB2 family C1_1 PF00130.17 EDN08200.1 - 0.078 12.7 8.9 0.62 9.8 1.0 2.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Far-17a_AIG1 PF04750.9 EDN08201.1 - 0.0002 20.5 21.0 0.00069 18.8 5.6 3.3 1 1 3 4 4 4 3 FAR-17a/AIG1-like protein DUF2632 PF10943.3 EDN08201.1 - 0.017 14.6 1.3 0.017 14.6 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2632) DUF1230 PF06799.6 EDN08201.1 - 2.7 7.8 10.0 3.2 7.5 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1230) DUF4088 PF13317.1 EDN08203.1 - 0.053 12.8 0.1 0.057 12.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) Sel1 PF08238.7 EDN08204.1 - 6.2e-15 55.2 6.9 0.00028 21.4 0.6 4.2 4 0 0 4 4 4 3 Sel1 repeat ATP-grasp_2 PF08442.5 EDN08205.1 - 2.6 7.3 4.6 3.7 6.8 3.1 1.4 1 1 0 1 1 1 0 ATP-grasp domain Chromo PF00385.19 EDN08206.1 - 0.00013 21.5 0.2 0.00022 20.8 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PLU-1 PF08429.6 EDN08208.1 - 0.0049 15.8 1.4 0.0067 15.3 0.4 1.6 2 0 0 2 2 2 1 PLU-1-like protein EAP30 PF04157.11 EDN08208.1 - 0.014 14.5 1.0 0.025 13.7 0.7 1.4 1 0 0 1 1 1 0 EAP30/Vps36 family Myb_DNA-binding PF00249.26 EDN08210.1 - 2.9e-10 40.0 0.6 6e-09 35.8 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN08210.1 - 3.3e-06 27.0 2.8 1.1e-05 25.3 0.1 2.5 2 1 1 3 3 3 1 Myb-like DNA-binding domain DUF1886 PF09171.5 EDN08210.1 - 0.047 12.7 0.1 0.065 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) BH4 PF02180.12 EDN08210.1 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Bcl-2 homology region 4 Zn_clus PF00172.13 EDN08213.1 - 1.3e-07 31.4 8.5 1.3e-07 31.4 5.9 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GvpG PF05120.7 EDN08214.1 - 0.034 13.9 2.1 0.087 12.6 1.4 1.7 1 0 0 1 1 1 0 Gas vesicle protein G HSCB_C PF07743.8 EDN08214.1 - 8 7.0 10.6 28 5.2 0.4 3.6 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain CP2 PF04516.10 EDN08215.1 - 6.3e-83 277.4 0.0 4.7e-80 268.0 0.0 2.3 2 0 0 2 2 2 2 CP2 transcription factor bZIP_1 PF00170.16 EDN08215.1 - 0.0099 15.8 4.5 0.0099 15.8 3.2 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EDN08215.1 - 0.014 15.2 6.4 0.057 13.2 0.7 2.3 2 0 0 2 2 2 0 Basic region leucine zipper GxGYxYP PF14323.1 EDN08215.1 - 0.16 10.6 0.8 0.26 9.9 0.5 1.2 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function Tegument_dsDNA PF12818.2 EDN08216.1 - 0.03 13.1 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 dsDNA viral tegument protein Acetyltransf_7 PF13508.1 EDN08216.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN08216.1 - 0.13 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Lac_bphage_repr PF06543.7 EDN08218.1 - 0.034 13.6 0.6 0.095 12.2 0.4 1.7 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor DUF1388 PF07142.7 EDN08219.1 - 0.00014 21.4 3.9 1.7 8.4 0.1 3.6 1 1 5 6 6 6 6 Repeat of unknown function (DUF1388) Collagen PF01391.13 EDN08219.1 - 0.59 9.7 11.2 18 4.9 7.8 2.9 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) DegS PF05384.6 EDN08220.1 - 8.9e-05 21.7 1.9 0.00013 21.2 1.3 1.2 1 0 0 1 1 1 1 Sensor protein DegS zf-C3HC4 PF00097.20 EDN08220.1 - 0.00047 19.7 8.2 0.00088 18.8 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN08220.1 - 0.001 18.6 9.6 0.0015 18.1 6.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NTR2 PF15458.1 EDN08220.1 - 0.0016 17.7 1.6 0.0019 17.5 1.1 1.1 1 0 0 1 1 1 1 Nineteen complex-related protein 2 zf-RING_5 PF14634.1 EDN08220.1 - 0.0038 16.9 8.0 0.0062 16.2 5.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Macoilin PF09726.4 EDN08220.1 - 0.0043 15.4 3.3 0.0054 15.0 2.3 1.1 1 0 0 1 1 1 1 Transmembrane protein TMF_TATA_bd PF12325.3 EDN08220.1 - 0.0053 16.4 1.4 0.0078 15.9 1.0 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF2730 PF10805.3 EDN08220.1 - 0.0064 16.2 0.5 0.0099 15.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) DivIC PF04977.10 EDN08220.1 - 0.0075 15.7 1.2 0.013 14.9 0.8 1.4 1 0 0 1 1 1 1 Septum formation initiator Med28 PF11594.3 EDN08220.1 - 0.012 15.7 0.7 0.019 15.1 0.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 28 Troponin PF00992.15 EDN08220.1 - 0.013 15.5 5.2 0.024 14.7 3.6 1.3 1 0 0 1 1 1 0 Troponin ADIP PF11559.3 EDN08220.1 - 0.019 14.8 1.9 0.032 14.1 1.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 EDN08220.1 - 0.025 14.5 5.4 0.042 13.7 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Fez1 PF06818.10 EDN08220.1 - 0.029 14.3 1.9 0.032 14.2 0.9 1.4 2 0 0 2 2 1 0 Fez1 HALZ PF02183.13 EDN08220.1 - 0.032 13.9 1.2 0.051 13.2 0.6 1.5 1 1 0 1 1 1 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 EDN08220.1 - 0.049 13.5 2.1 8.7 6.3 1.5 2.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) RmuC PF02646.11 EDN08220.1 - 0.05 12.4 1.0 0.071 11.9 0.7 1.1 1 0 0 1 1 1 0 RmuC family TMF_DNA_bd PF12329.3 EDN08220.1 - 0.051 13.3 1.3 0.093 12.5 0.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spectrin PF00435.16 EDN08220.1 - 0.053 13.8 0.8 0.076 13.3 0.6 1.2 1 0 0 1 1 1 0 Spectrin repeat DUF641 PF04859.7 EDN08220.1 - 0.053 13.2 1.0 0.086 12.5 0.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.5 EDN08220.1 - 0.059 13.4 0.7 0.092 12.8 0.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HAUS5 PF14817.1 EDN08220.1 - 0.065 11.7 2.9 0.086 11.3 2.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF1192 PF06698.6 EDN08220.1 - 0.067 13.0 2.5 0.14 12.0 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4618 PF15397.1 EDN08220.1 - 0.068 12.4 1.5 0.091 12.0 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Tropomyosin_1 PF12718.2 EDN08220.1 - 0.075 12.8 4.9 0.12 12.2 3.4 1.2 1 0 0 1 1 1 0 Tropomyosin like zf-C3HC4_2 PF13923.1 EDN08220.1 - 0.092 12.7 9.2 0.17 11.9 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4164 PF13747.1 EDN08220.1 - 0.15 12.2 5.0 0.26 11.4 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF3373 PF11853.3 EDN08220.1 - 0.17 10.3 0.2 0.21 10.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Apelin PF15360.1 EDN08220.1 - 0.18 12.0 0.2 0.18 12.0 0.2 2.1 2 1 0 2 2 2 0 APJ endogenous ligand Prefoldin_2 PF01920.15 EDN08220.1 - 0.21 11.3 4.1 0.41 10.4 2.9 1.5 1 1 0 1 1 1 0 Prefoldin subunit IncA PF04156.9 EDN08220.1 - 0.46 10.0 3.1 0.67 9.5 2.2 1.2 1 0 0 1 1 1 0 IncA protein CENP-Q PF13094.1 EDN08220.1 - 0.5 10.3 6.2 1.2 9.1 4.2 1.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit zf-RING_2 PF13639.1 EDN08220.1 - 0.7 9.7 12.6 1.5 8.7 8.7 1.6 1 0 0 1 1 1 0 Ring finger domain DUF3435 PF11917.3 EDN08221.1 - 2.8e-127 424.9 0.0 3.7e-127 424.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) HTH_29 PF13551.1 EDN08222.1 - 3.5e-06 27.1 0.0 1.4e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EDN08222.1 - 6e-06 25.7 0.2 0.0007 19.1 0.0 2.4 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EDN08222.1 - 7.9e-06 25.6 0.0 6.5e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_33 PF13592.1 EDN08222.1 - 2.7e-05 23.6 0.0 8e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_38 PF13936.1 EDN08222.1 - 4.3e-05 22.9 0.1 0.00055 19.4 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.1 EDN08222.1 - 0.001 18.9 0.0 0.1 12.6 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.13 EDN08222.1 - 0.0081 15.8 0.0 0.013 15.2 0.0 1.4 1 1 0 1 1 1 1 'Paired box' domain HTH_Tnp_IS630 PF01710.11 EDN08222.1 - 0.021 14.4 0.0 0.031 13.9 0.0 1.5 1 1 0 1 1 1 0 Transposase Terminase_5 PF06056.7 EDN08222.1 - 0.051 13.1 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Nucleo_P87 PF07267.6 EDN08223.1 - 0.026 13.2 3.1 0.033 12.8 2.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.1 EDN08223.1 - 0.077 13.3 0.8 0.11 12.7 0.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3435 PF11917.3 EDN08224.1 - 8.3e-129 429.9 0.1 3.2e-116 388.4 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) zf-C2H2 PF00096.21 EDN08224.1 - 0.51 10.7 12.3 6 7.4 1.5 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN08224.1 - 3.3 8.2 11.7 4 7.9 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Kdo PF06293.9 EDN08225.1 - 0.0018 17.3 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DDE_1 PF03184.14 EDN08227.1 - 9.2e-51 172.0 0.0 2.1e-50 170.8 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN08227.1 - 7.4e-06 25.7 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3723 PF12520.3 EDN08229.1 - 3.5e-96 322.7 15.4 7.8e-54 183.0 0.0 5.3 2 2 3 5 5 5 4 Protein of unknown function (DUF3723) DUF3435 PF11917.3 EDN08230.1 - 7.3e-160 532.2 0.7 9.5e-160 531.8 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Meckelin PF09773.4 EDN08230.1 - 0.16 9.6 0.0 0.32 8.7 0.0 1.4 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) DUF3712 PF12505.3 EDN08231.1 - 7e-25 87.4 3.0 4.2e-24 84.9 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EDN08231.1 - 0.00027 21.2 0.1 0.0014 18.9 0.0 2.3 2 1 0 2 2 2 1 Late embryogenesis abundant protein Big_2 PF02368.13 EDN08231.1 - 0.055 13.3 0.1 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) DUF1279 PF06916.8 EDN08231.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Glyco_hydro_18 PF00704.23 EDN08232.1 - 1e-62 212.6 0.0 1.5e-62 212.0 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 EDN08232.1 - 0.038 13.6 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) zf-CCCH PF00642.19 EDN08233.1 - 5.1e-19 67.5 30.3 1.5e-08 34.1 0.6 5.2 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 EDN08233.1 - 0.1 12.1 2.5 3 7.4 0.1 3.2 2 0 0 2 2 2 0 Putative zinc-finger domain zf-CCCH_2 PF14608.1 EDN08233.1 - 0.16 12.0 0.2 0.16 12.0 0.1 5.3 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type LRV_FeS PF05484.6 EDN08233.1 - 1.1 8.9 17.3 0.83 9.2 0.3 4.9 3 2 1 5 5 5 0 LRV protein FeS4 cluster Flavodoxin_1 PF00258.20 EDN08235.1 - 2.4e-09 37.3 0.0 4.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EDN08235.1 - 6.1e-08 32.3 0.0 8.3e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EDN08235.1 - 1.5e-07 31.1 0.0 1.9e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EDN08235.1 - 0.02 14.8 0.0 0.89 9.5 0.0 2.2 1 1 1 2 2 2 0 Flavodoxin domain Flavodoxin_4 PF12682.2 EDN08235.1 - 0.021 14.1 0.1 0.073 12.4 0.1 1.8 1 1 0 1 1 1 0 Flavodoxin NPL4 PF05021.10 EDN08236.1 - 4.9e-116 387.1 0.0 1.7e-115 385.4 0.0 1.7 1 1 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EDN08236.1 - 1e-71 239.3 0.1 1.7e-71 238.6 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region DUF2417 PF10329.4 EDN08237.1 - 3.2e-82 275.4 0.9 3.6e-82 275.2 0.1 1.4 2 0 0 2 2 2 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EDN08239.1 - 2.6e-22 79.8 0.0 4.4e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN08239.1 - 9.2e-08 31.9 0.0 2.6e-07 30.4 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN08239.1 - 2.9e-06 27.0 0.0 0.035 13.6 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 EDN08239.1 - 0.0082 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EDN08239.1 - 0.053 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein WD40 PF00400.27 EDN08240.1 - 6.8e-57 187.4 23.4 5.8e-11 41.8 0.8 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EDN08240.1 - 1.7e-47 161.0 0.0 2.5e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EDN08240.1 - 7.9e-05 20.9 2.3 0.028 12.5 0.1 3.5 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDN08240.1 - 0.00092 18.0 0.0 1.8 7.2 0.0 3.8 2 1 1 3 3 3 2 Nup133 N terminal like LisH PF08513.6 EDN08240.1 - 0.002 17.8 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 LisH Med11 PF10280.4 EDN08241.1 - 9.4e-38 128.8 0.0 1.1e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein F_actin_cap_B PF01115.12 EDN08242.1 - 1.5e-107 358.3 0.0 1.8e-107 358.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Helicase_C PF00271.26 EDN08243.1 - 3e-20 71.8 0.0 7.6e-20 70.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN08243.1 - 4.6e-07 29.4 0.0 1.3e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN08243.1 - 0.0012 18.6 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DPM2 PF07297.7 EDN08247.1 - 7.9e-35 118.9 0.6 1.1e-34 118.5 0.4 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EDN08247.1 - 0.0018 17.9 0.6 0.0023 17.5 0.4 1.2 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 EDN08247.1 - 0.008 16.0 0.2 0.008 16.0 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) DUF4083 PF13314.1 EDN08247.1 - 0.039 13.7 1.1 0.043 13.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF1469 PF07332.6 EDN08247.1 - 0.099 12.3 0.5 0.13 11.9 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) COX14 PF14880.1 EDN08247.1 - 0.14 11.7 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF1049 PF06305.6 EDN08247.1 - 3 7.3 4.5 0.43 10.0 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) PspC PF04024.7 EDN08247.1 - 7.4 6.1 6.9 4.1 6.9 1.0 2.1 2 0 0 2 2 2 0 PspC domain MA3 PF02847.12 EDN08248.1 - 1.1e-25 89.5 0.0 2.8e-25 88.2 0.0 1.8 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.14 EDN08248.1 - 3.6e-20 72.2 1.1 3.7e-19 68.9 0.7 2.2 1 1 0 1 1 1 1 MIF4G domain RRM_1 PF00076.17 EDN08249.1 - 2.4e-16 59.1 0.0 2e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN08249.1 - 4.2e-13 49.0 0.0 1.2e-09 38.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN08249.1 - 1.4e-05 24.8 0.0 9.3e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EDN08249.1 - 0.061 13.0 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 DUF1772 PF08592.6 EDN08250.1 - 4.7e-08 32.8 0.2 6.4e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Glucosamine_iso PF01182.15 EDN08252.1 - 1.2e-58 198.1 0.0 1.5e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PD40 PF07676.7 EDN08252.1 - 0.2 11.3 0.7 12 5.6 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF3458 PF11940.3 EDN08253.1 - 0.027 13.3 0.4 0.039 12.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) TMEM247 PF15444.1 EDN08253.1 - 0.13 12.1 0.1 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 247 WD40 PF00400.27 EDN08255.1 - 2.4e-24 84.2 15.7 1.2e-07 31.3 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Hyccin PF09790.4 EDN08255.1 - 0.25 10.1 0.0 0.49 9.2 0.0 1.4 1 0 0 1 1 1 0 Hyccin TPR_9 PF13371.1 EDN08256.1 - 0.0086 15.9 0.8 0.021 14.6 0.5 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat YqeY PF09424.5 EDN08256.1 - 0.041 13.7 0.1 0.068 13.0 0.1 1.3 1 0 0 1 1 1 0 Yqey-like protein TPR_11 PF13414.1 EDN08256.1 - 0.2 11.3 0.5 0.5 10.0 0.2 1.7 2 0 0 2 2 2 0 TPR repeat RabGAP-TBC PF00566.13 EDN08257.1 - 5.6e-07 29.2 0.2 7.2e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 EDN08259.1 - 1.6e-13 49.2 3.1 4.6e-06 26.0 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EDN08259.1 - 3.1e-12 44.8 3.9 2.3e-05 23.3 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EDN08259.1 - 1.1e-09 38.3 0.3 3.8e-09 36.5 0.2 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EDN08259.1 - 3.1e-09 35.7 6.6 0.00015 20.9 1.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EDN08259.1 - 4.1e-06 26.3 0.1 0.041 13.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 EDN08259.1 - 0.026 14.4 0.0 3 7.8 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain Afi1 PF07792.7 EDN08260.1 - 7.2e-62 207.6 0.0 1.3e-61 206.8 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EDN08260.1 - 3.8e-37 126.4 0.0 6.4e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EDN08260.1 - 1.6e-09 36.7 0.1 0.002 16.6 0.1 3.9 4 1 1 5 5 5 3 Transport protein Avl9 DUF72 PF01904.13 EDN08260.1 - 0.027 14.2 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF72 Formyl_trans_N PF00551.14 EDN08264.1 - 6.3e-39 133.3 0.1 7.5e-39 133.1 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase Phos_pyr_kin PF08543.7 EDN08265.1 - 4.7e-12 45.6 0.0 1.1e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EDN08265.1 - 7e-09 35.2 5.0 8.8e-08 31.6 0.3 2.9 3 1 0 3 3 3 2 pfkB family carbohydrate kinase dUTPase PF00692.14 EDN08266.1 - 6e-44 148.6 0.0 7.7e-44 148.2 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 EDN08266.1 - 0.017 13.5 0.0 0.023 13.0 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) APH PF01636.18 EDN08267.1 - 2.2e-40 138.9 0.1 8.7e-40 136.9 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EDN08267.1 - 5.9e-06 25.6 0.0 1.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EDN08267.1 - 2e-05 24.2 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EDN08267.1 - 4.2e-05 22.7 0.0 0.00035 19.7 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EDN08267.1 - 0.019 14.3 0.0 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Fructosamin_kin PF03881.9 EDN08267.1 - 0.024 13.6 0.0 1.6 7.6 0.0 2.3 2 1 0 2 2 2 0 Fructosamine kinase DUF1679 PF07914.6 EDN08267.1 - 0.069 11.7 0.0 0.15 10.6 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) zf-C2H2_4 PF13894.1 EDN08269.1 - 4.9e-09 35.8 11.2 0.00029 20.9 1.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN08269.1 - 1.2e-08 34.7 10.9 0.0016 18.6 1.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDN08269.1 - 0.00018 21.6 13.4 0.05 13.9 0.1 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-Di19 PF05605.7 EDN08269.1 - 1.1 9.4 11.2 0.14 12.2 0.7 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding PQ-loop PF04193.9 EDN08270.1 - 8.9e-37 124.4 5.3 1.1e-19 69.7 0.3 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF998 PF06197.8 EDN08271.1 - 0.026 13.8 18.4 0.0099 15.2 7.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Ribosomal_L29e PF01779.12 EDN08272.1 - 4.7e-19 67.9 9.3 8.9e-19 67.0 6.4 1.5 1 0 0 1 1 1 1 Ribosomal L29e protein family WD40 PF00400.27 EDN08273.1 - 0.011 15.6 0.0 2.1 8.3 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF2414 PF10309.4 EDN08274.1 - 1.4e-22 79.1 0.1 2.3e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Myb_DNA-binding PF00249.26 EDN08275.1 - 4.8e-11 42.5 3.4 8.3e-09 35.3 0.1 3.0 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN08275.1 - 1.5e-08 34.6 5.3 0.0029 17.6 0.6 3.3 1 1 1 3 3 3 2 Myb-like DNA-binding domain DUF2774 PF11242.3 EDN08275.1 - 0.0016 18.3 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2774) HTH_38 PF13936.1 EDN08275.1 - 0.018 14.5 0.1 0.045 13.2 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 EDN08275.1 - 0.069 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EDN08275.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Glyco_transf_41 PF13844.1 EDN08276.1 - 1.1e-101 340.0 0.1 8.5e-53 178.9 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EDN08276.1 - 1.4e-19 69.4 23.2 7.7e-09 35.0 0.1 5.1 5 0 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 EDN08276.1 - 4.8e-16 57.3 16.0 0.00077 19.2 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 EDN08276.1 - 8.3e-16 56.8 14.7 0.002 17.6 0.1 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EDN08276.1 - 3.7e-12 46.0 12.2 3.6e-06 26.8 0.2 4.4 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EDN08276.1 - 1.3e-11 44.8 17.1 1.3e-05 25.7 0.7 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDN08276.1 - 1.9e-11 43.4 9.0 0.0021 18.5 0.1 5.5 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 EDN08276.1 - 3.2e-10 39.0 0.9 0.0017 17.9 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDN08276.1 - 8.9e-10 37.6 6.7 0.14 11.9 0.0 5.6 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 EDN08276.1 - 5.6e-09 35.6 15.6 0.02 14.8 0.4 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDN08276.1 - 7.2e-09 35.1 11.6 0.14 12.4 0.2 5.5 6 0 0 6 6 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 EDN08276.1 - 8.2e-07 29.2 10.4 0.0014 18.9 0.1 3.2 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_5 PF12688.2 EDN08276.1 - 0.00017 21.5 0.8 0.05 13.6 0.1 2.9 3 0 0 3 3 3 1 Tetratrico peptide repeat BTAD PF03704.12 EDN08276.1 - 0.00047 20.4 0.1 1.3 9.3 0.0 2.9 2 0 0 2 2 2 2 Bacterial transcriptional activator domain Apc3 PF12895.2 EDN08276.1 - 0.00064 19.8 1.1 0.13 12.4 0.0 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EDN08276.1 - 0.00093 18.9 5.5 1.2 9.0 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EDN08276.1 - 0.0038 17.5 4.6 4.2 8.0 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EDN08276.1 - 0.0045 16.0 0.2 1.7 7.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 EDN08276.1 - 0.048 14.0 3.9 6.6 7.4 0.4 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.9 EDN08276.1 - 0.18 11.0 0.0 0.99 8.5 0.0 1.9 2 0 0 2 2 2 0 Coatomer epsilon subunit Sel1 PF08238.7 EDN08276.1 - 8.1 7.2 8.5 1.3 9.7 0.3 3.8 3 1 0 3 3 3 0 Sel1 repeat Ribosomal_L11 PF00298.14 EDN08278.1 - 0.0025 17.9 0.0 0.0036 17.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.10 EDN08279.1 - 5.8e-82 274.7 0.0 1e-81 273.8 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EDN08279.1 - 6e-34 115.5 0.1 1.5e-33 114.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EDN08279.1 - 1.3e-30 105.7 0.1 3e-30 104.5 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EDN08279.1 - 8.7e-11 41.3 0.0 2.1e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat DNA_primase_lrg PF04104.9 EDN08280.1 - 2.8e-83 279.1 0.0 3.9e-83 278.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit ADK PF00406.17 EDN08281.1 - 4.9e-35 120.6 0.0 3.5e-33 114.5 0.0 2.1 1 1 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EDN08281.1 - 1.7e-14 53.2 0.0 3.2e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EDN08281.1 - 0.00015 22.6 0.0 0.00046 21.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDN08281.1 - 0.0003 21.0 0.0 0.002 18.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDN08281.1 - 0.0019 18.0 0.0 0.016 15.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 EDN08281.1 - 0.076 11.7 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 ArgK protein SNase PF00565.12 EDN08282.1 - 2.9e-21 75.7 0.0 3.8e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Mito_carr PF00153.22 EDN08283.1 - 3.9e-28 96.9 0.1 7.1e-16 57.7 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein ADK PF00406.17 EDN08284.1 - 1.5e-13 50.9 0.0 1.9e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 EDN08284.1 - 8.9e-05 23.3 0.0 9.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDN08284.1 - 0.00068 19.9 0.0 0.00072 19.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDN08284.1 - 0.0053 16.6 0.0 0.0064 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EDN08284.1 - 0.0083 14.9 0.0 0.0093 14.7 0.0 1.1 1 0 0 1 1 1 1 ArgK protein Zeta_toxin PF06414.7 EDN08284.1 - 0.022 13.8 0.1 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 EDN08284.1 - 0.025 14.7 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EDN08284.1 - 0.028 14.3 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDN08284.1 - 0.048 13.3 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EDN08284.1 - 0.055 12.6 0.0 0.055 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Guanylate_kin PF00625.16 EDN08284.1 - 0.063 12.7 0.0 0.074 12.4 0.0 1.1 1 0 0 1 1 1 0 Guanylate kinase FtsK_SpoIIIE PF01580.13 EDN08284.1 - 0.096 12.1 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 EDN08284.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EDN08284.1 - 0.13 12.5 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 ABC transporter AAA PF00004.24 EDN08284.1 - 0.14 12.3 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Peptidase_C2 PF00648.16 EDN08285.1 - 9.9e-16 57.5 0.0 1.7e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EDN08285.1 - 0.00011 21.8 0.0 0.0055 16.3 0.0 2.7 2 1 0 2 2 2 1 Calpain large subunit, domain III DUF605 PF04652.11 EDN08286.1 - 1.4e-77 261.6 0.1 1.7e-77 261.3 0.1 1.1 1 0 0 1 1 1 1 Vta1 like SRP9-21 PF05486.7 EDN08286.1 - 0.031 14.0 0.1 0.074 12.8 0.1 1.6 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) NAD_binding_3 PF03447.11 EDN08286.1 - 0.064 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Epimerase PF01370.16 EDN08287.1 - 2.4e-21 76.2 0.0 3.1e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EDN08287.1 - 1.1e-08 34.3 0.0 1.7e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EDN08287.1 - 2.7e-05 22.9 0.0 0.00015 20.5 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EDN08287.1 - 0.0021 17.0 0.0 0.0033 16.3 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Topoisom_I_N PF02919.10 EDN08288.1 - 1.4e-97 325.1 1.2 1.4e-97 325.1 0.8 2.4 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EDN08288.1 - 3.4e-50 170.3 0.3 6.2e-50 169.4 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core RolB_RolC PF02027.12 EDN08288.1 - 0.075 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 RolB/RolC glucosidase family ATP-synt PF00231.14 EDN08289.1 - 3.2e-71 240.0 8.4 3.7e-71 239.8 5.8 1.0 1 0 0 1 1 1 1 ATP synthase Ribosomal_S3_C PF00189.15 EDN08289.1 - 0.05 13.8 0.2 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain Thioredoxin PF00085.15 EDN08292.1 - 5.8e-31 106.2 0.0 1.5e-25 88.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EDN08292.1 - 2.1e-07 31.1 0.3 0.0007 19.7 0.1 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDN08292.1 - 1.2e-05 25.3 0.1 0.002 18.2 0.0 3.5 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_6 PF13848.1 EDN08292.1 - 3.1e-05 23.8 0.0 7.6e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EDN08292.1 - 0.006 16.5 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EDN08292.1 - 0.015 14.9 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_3 PF13192.1 EDN08292.1 - 0.14 12.0 0.0 0.76 9.6 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain GNAT_acetyltr_2 PF13718.1 EDN08293.1 - 2.4e-79 265.2 0.0 4e-79 264.5 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EDN08293.1 - 1.9e-65 219.8 0.0 5.9e-65 218.1 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EDN08293.1 - 7.8e-40 134.4 0.0 1.9e-39 133.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EDN08293.1 - 3.8e-33 113.6 0.4 1.1e-32 112.0 0.3 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EDN08293.1 - 0.034 14.3 0.0 0.099 12.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN08293.1 - 0.038 14.0 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MARVEL PF01284.18 EDN08294.1 - 0.0014 18.4 1.4 0.0023 17.7 0.9 1.4 1 0 0 1 1 1 1 Membrane-associating domain 7tm_7 PF08395.7 EDN08294.1 - 0.0017 17.4 0.1 0.0024 16.9 0.1 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor Glyco_transf_90 PF05686.7 EDN08294.1 - 0.017 13.8 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 90 SieB PF14163.1 EDN08294.1 - 0.024 14.2 1.2 0.037 13.6 0.8 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B Glyco_transf_90 PF05686.7 EDN08295.1 - 0.00019 20.2 0.0 0.00077 18.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 90 Upf2 PF04050.9 EDN08295.1 - 0.017 14.8 1.6 0.025 14.3 1.1 1.2 1 0 0 1 1 1 0 Up-frameshift suppressor 2 DUF4614 PF15391.1 EDN08296.1 - 0.029 14.1 6.4 0.048 13.4 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Polysacc_synt_4 PF04669.8 EDN08296.1 - 0.064 12.6 0.5 0.11 11.8 0.3 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis Vps8 PF12816.2 EDN08297.1 - 2.6e-72 242.2 0.1 4.3e-72 241.4 0.1 1.4 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EDN08297.1 - 0.00013 21.5 0.0 0.0014 18.2 0.0 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS Pox_D3 PF04580.8 EDN08297.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein RVT_1 PF00078.22 EDN08303.1 - 4.3e-26 91.6 0.0 6.5e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN08303.1 - 7.6e-16 57.8 0.0 2e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN08303.1 - 0.00025 21.0 0.0 0.00046 20.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Clr2 PF10383.4 EDN08305.1 - 6.2e-41 139.6 0.0 9.9e-41 138.9 0.0 1.3 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 p450 PF00067.17 EDN08307.1 - 5.6e-24 84.4 0.0 2.9e-22 78.8 0.0 2.8 1 1 0 1 1 1 1 Cytochrome P450 ABC_membrane_2 PF06472.10 EDN08308.1 - 5.7e-79 265.1 0.0 1.5e-78 263.7 0.0 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EDN08308.1 - 3e-15 56.7 0.0 5.6e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA PF00004.24 EDN08308.1 - 0.025 14.7 0.0 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN08308.1 - 0.031 14.2 0.0 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.7 EDN08308.1 - 0.034 13.1 0.0 0.25 10.3 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EDN08308.1 - 0.042 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EDN08308.1 - 0.057 13.3 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EDN08308.1 - 0.065 13.5 0.1 0.89 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EDN08308.1 - 0.084 13.0 0.0 0.23 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EDN08308.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PepSY_2 PF13670.1 EDN08308.1 - 0.11 12.4 0.9 0.22 11.4 0.6 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain AAA_17 PF13207.1 EDN08308.1 - 0.11 13.3 1.8 0.7 10.7 0.1 2.5 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EDN08308.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EDN08308.1 - 0.2 11.7 0.0 0.56 10.2 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain Harakiri PF15196.1 EDN08309.1 - 0.071 13.3 0.4 0.092 12.9 0.3 1.2 1 0 0 1 1 1 0 Activator of apoptosis harakiri NIF PF03031.13 EDN08310.1 - 8.1e-36 123.0 0.5 8.5e-17 61.2 0.0 2.4 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase Serglycin PF04360.7 EDN08310.1 - 0.021 14.5 1.0 0.14 11.8 0.1 2.5 2 0 0 2 2 2 0 Serglycin LRR_4 PF12799.2 EDN08311.1 - 1.1e-40 136.6 31.7 1.6e-09 37.1 2.6 6.4 4 2 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDN08311.1 - 1e-20 73.1 33.3 8.3e-09 35.0 4.5 5.3 2 1 2 5 5 5 4 Leucine rich repeat LRR_7 PF13504.1 EDN08311.1 - 4.5e-16 56.1 13.5 0.46 10.8 0.0 10.3 10 0 0 10 10 10 3 Leucine rich repeat LRR_1 PF00560.28 EDN08311.1 - 6.6e-14 49.8 28.6 0.05 13.6 0.5 10.2 10 0 0 10 10 10 6 Leucine Rich Repeat LRR_9 PF14580.1 EDN08311.1 - 3.3e-10 39.8 11.4 2.7e-07 30.3 2.5 3.7 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.1 EDN08311.1 - 6.3e-10 38.0 23.2 0.12 12.4 0.4 8.7 5 3 4 9 9 9 4 Leucine Rich repeat DUF3744 PF12558.3 EDN08311.1 - 0.042 14.3 11.4 6.5 7.2 0.1 4.6 3 1 3 6 6 6 0 ATP-binding cassette cobalt transporter Orexin_rec2 PF03827.8 EDN08311.1 - 3.8 7.6 5.7 47 4.1 0.1 3.9 4 1 1 5 5 5 0 Orexin receptor type 2 Aldo_ket_red PF00248.16 EDN08312.1 - 5.8e-31 107.3 0.2 3.4e-30 104.8 0.2 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.17 EDN08313.1 - 1.7e-52 174.9 1.1 1.6e-15 56.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN08313.1 - 1.1e-46 156.6 0.4 3e-14 52.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN08313.1 - 2.6e-24 84.7 0.3 2.8e-06 27.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EDN08313.1 - 6.8e-05 22.5 0.4 0.12 12.1 0.0 4.1 4 0 0 4 4 4 1 Limkain b1 RRM_3 PF08777.6 EDN08313.1 - 0.036 13.8 0.6 22 4.9 0.0 3.8 4 0 0 4 4 4 0 RNA binding motif RNA_bind PF08675.6 EDN08313.1 - 0.051 13.5 0.1 11 6.0 0.0 3.4 3 1 1 4 4 4 0 RNA binding domain Dynein_light PF01221.13 EDN08314.1 - 5.3e-41 138.5 2.6 6.3e-41 138.2 1.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF950 PF06106.6 EDN08314.1 - 0.033 14.2 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Staphylococcus protein of unknown function (DUF950) RNase_E_G PF10150.4 EDN08314.1 - 0.047 12.9 0.2 0.055 12.7 0.1 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family Ribosomal_L6e PF01159.14 EDN08314.1 - 0.069 13.3 0.4 0.087 13.0 0.3 1.1 1 0 0 1 1 1 0 Ribosomal protein L6e Viral_DNA_bp PF00747.12 EDN08314.1 - 0.072 10.3 0.0 0.073 10.2 0.0 1.0 1 0 0 1 1 1 0 ssDNA binding protein DUF3139 PF11337.3 EDN08314.1 - 0.1 12.8 0.5 0.18 12.1 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3139) SpoIIIAH PF12685.2 EDN08314.1 - 3.1 7.2 6.5 3.7 6.9 4.5 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein MFS_1 PF07690.11 EDN08317.1 - 1.9e-39 135.4 49.6 8.8e-38 129.9 34.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN08317.1 - 1.7e-12 46.7 27.4 1.4e-08 33.7 6.6 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter UNC-93 PF05978.11 EDN08317.1 - 0.0056 16.1 5.2 0.0056 16.1 3.6 3.0 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 DUF2919 PF11143.3 EDN08317.1 - 0.037 13.8 4.2 0.029 14.1 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) MIF4G_like PF09088.6 EDN08317.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 MIF4G like DIOX_N PF14226.1 EDN08318.1 - 4.3e-28 98.1 0.0 4.8e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF4139 PF13598.1 EDN08319.1 - 2.1e-48 165.2 0.0 9.3e-36 123.7 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EDN08319.1 - 4.6e-14 52.7 0.4 4.6e-14 52.7 0.3 3.7 4 1 0 4 4 4 1 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 EDN08319.1 - 9.3 5.7 13.1 17 4.9 0.1 3.3 3 0 0 3 3 3 0 IncA protein Sec61_beta PF03911.11 EDN08320.1 - 3.7e-19 68.2 0.9 5.8e-19 67.6 0.6 1.3 1 0 0 1 1 1 1 Sec61beta family p450 PF00067.17 EDN08321.1 - 6.2e-10 38.1 0.0 8.3e-10 37.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 COPI_assoc PF08507.5 EDN08322.1 - 0.043 13.4 0.2 0.043 13.4 0.1 3.8 3 2 2 5 5 5 0 COPI associated protein PCNA_C PF02747.10 EDN08325.1 - 4.9e-49 165.5 0.0 1.1e-48 164.3 0.0 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 EDN08325.1 - 7.2e-48 161.2 3.9 7.2e-48 161.2 1.6 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 EDN08325.1 - 4.8e-08 32.4 0.0 6.2e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Rad9 Vezatin PF12632.2 EDN08326.1 - 3e-16 59.2 2.0 7.5e-08 31.7 0.6 2.7 2 1 1 3 3 3 2 Mysoin-binding motif of peroxisomes Polysacc_synt_C PF14667.1 EDN08326.1 - 0.00011 22.0 1.3 0.00018 21.3 0.9 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain CH PF00307.26 EDN08327.1 - 0.001 19.0 0.0 0.54 10.3 0.0 3.3 2 1 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.22 EDN08327.1 - 0.0035 16.8 4.6 0.013 15.0 3.2 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif CAMSAP_CH PF11971.3 EDN08327.1 - 0.0057 16.2 0.0 2.9 7.6 0.0 2.4 2 0 0 2 2 2 2 CAMSAP CH domain Ribosomal_60s PF00428.14 EDN08327.1 - 1.6 9.1 10.2 0.1 13.0 3.2 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Spt5_N PF11942.3 EDN08328.1 - 0.46 11.1 5.7 0.74 10.4 3.9 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF2457 PF10446.4 EDN08329.1 - 4.5e-122 408.0 62.4 2.7e-73 247.2 30.0 3.4 2 1 2 4 4 4 3 Protein of unknown function (DUF2457) TFIIF_alpha PF05793.7 EDN08329.1 - 0.00062 18.2 26.2 0.001 17.5 18.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.7 EDN08329.1 - 0.0035 16.6 26.0 0.0073 15.6 18.0 1.5 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.7 EDN08329.1 - 0.053 11.4 33.6 0.084 10.7 23.3 1.3 1 0 0 1 1 1 0 Nop14-like family Arf PF00025.16 EDN08330.1 - 1.6e-62 209.8 0.0 1.8e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EDN08330.1 - 2.8e-08 32.8 0.2 0.00011 21.0 0.0 2.3 1 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EDN08330.1 - 1.8e-07 30.5 0.0 2.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EDN08330.1 - 2.5e-07 30.6 0.0 3.3e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDN08330.1 - 2.5e-06 27.9 0.0 3.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EDN08330.1 - 2.6e-05 23.4 0.0 2.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EDN08330.1 - 2.9e-05 23.5 0.0 4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 EDN08330.1 - 0.005 16.3 0.0 0.32 10.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EDN08330.1 - 0.086 12.3 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EDN08330.1 - 0.13 11.9 0.0 3.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Metallophos PF00149.23 EDN08331.1 - 1.9e-27 95.9 0.0 2.4e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_4 PF12799.2 EDN08332.1 - 2.4e-19 68.5 7.1 1.4e-07 30.9 0.6 5.6 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDN08332.1 - 2.3e-14 52.9 15.7 8.1e-08 31.9 2.6 4.4 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 EDN08332.1 - 8.5e-12 43.3 7.5 0.16 12.0 0.1 7.1 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 EDN08332.1 - 7.1e-06 25.5 3.4 23 5.4 0.0 6.8 6 1 1 7 7 7 1 Leucine Rich repeat LRR_7 PF13504.1 EDN08332.1 - 3.4e-05 23.3 7.4 27 5.5 0.1 6.9 7 0 0 7 7 7 1 Leucine rich repeat DUF3336 PF11815.3 EDN08335.1 - 1.1e-43 148.1 1.2 2e-43 147.3 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EDN08335.1 - 4.9e-19 69.0 0.1 2.7e-18 66.6 0.0 2.3 2 1 0 2 2 2 1 Patatin-like phospholipase DUF4404 PF14357.1 EDN08335.1 - 0.045 14.1 0.2 0.75 10.2 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TPR_11 PF13414.1 EDN08336.1 - 4.7e-21 74.2 15.9 0.00013 21.5 0.1 8.4 7 1 2 9 9 9 4 TPR repeat TPR_19 PF14559.1 EDN08336.1 - 2.2e-19 69.5 10.8 9.7e-07 29.0 0.0 6.5 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 EDN08336.1 - 1.4e-15 56.1 11.5 0.048 13.8 0.0 8.4 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDN08336.1 - 9.9e-14 50.6 8.5 0.00027 21.3 0.1 7.3 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN08336.1 - 1.9e-13 50.6 12.9 1.5e-05 25.4 0.2 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EDN08336.1 - 5.9e-10 39.1 14.5 0.0047 17.0 0.3 5.8 6 0 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EDN08336.1 - 1e-08 34.4 16.5 0.22 11.5 0.2 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDN08336.1 - 1.8e-06 27.8 21.7 0.0044 16.9 1.1 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDN08336.1 - 4.2e-06 26.1 18.9 0.72 9.7 0.4 7.7 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 EDN08336.1 - 8.3e-06 25.2 4.6 3.9 7.4 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 EDN08336.1 - 1.5e-05 25.0 2.2 3.3 7.8 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EDN08336.1 - 3.9e-05 23.9 4.8 0.15 12.3 0.1 3.4 3 0 0 3 3 3 2 Alkyl sulfatase dimerisation TPR_15 PF13429.1 EDN08336.1 - 0.00029 19.9 5.8 1.4 7.9 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDN08336.1 - 0.00064 19.5 1.1 0.0097 15.7 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 EDN08336.1 - 0.013 15.8 2.0 25 5.6 0.1 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat ChAPs PF09295.5 EDN08336.1 - 0.11 11.2 0.1 0.34 9.6 0.0 1.8 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_1 PF00515.23 EDN08336.1 - 0.13 11.9 20.3 8.9 6.1 0.1 8.3 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDN08336.1 - 0.24 11.9 11.8 2.7 8.6 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat O-FucT PF10250.4 EDN08337.1 - 0.071 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase SAM_2 PF07647.12 EDN08338.1 - 7.5e-09 35.3 0.2 1.5e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EDN08338.1 - 0.0001 22.4 0.2 0.00022 21.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Rab5ip PF07019.7 EDN08339.1 - 4.8e-11 42.6 7.5 2.7e-09 37.0 5.2 2.1 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) MFS_1 PF07690.11 EDN08340.1 - 2.9e-18 65.6 44.6 2.9e-18 65.6 30.9 3.5 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN08340.1 - 1.3e-08 33.4 13.6 2.1e-06 26.2 1.6 2.2 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sulfate_transp PF00916.15 EDN08341.1 - 5.1e-69 232.3 8.5 1.1e-68 231.2 5.9 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EDN08341.1 - 5.4e-25 86.8 2.3 5.4e-25 86.8 1.6 3.7 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EDN08341.1 - 1.4e-07 30.9 0.0 2.6e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 EDN08341.1 - 6.7 6.5 9.6 0.092 12.4 0.8 2.3 2 0 0 2 2 2 0 Stannin transmembrane CTDII PF01556.13 EDN08343.1 - 4.2e-10 39.3 0.0 6.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain URO-D PF01208.12 EDN08344.1 - 4.7e-25 88.2 0.0 5.1e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) URO-D PF01208.12 EDN08345.1 - 2.6e-06 26.6 0.1 4.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) WD40 PF00400.27 EDN08345.1 - 4.1e-06 26.4 4.6 0.095 12.6 0.2 4.9 5 1 0 5 5 5 2 WD domain, G-beta repeat CPSF_A PF03178.10 EDN08345.1 - 0.091 11.8 0.0 0.21 10.6 0.0 1.6 1 0 0 1 1 1 0 CPSF A subunit region Ribosomal_L10 PF00466.15 EDN08346.1 - 1e-24 86.3 0.4 2.9e-24 84.8 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EDN08346.1 - 2.4e-13 50.2 7.3 2.4e-13 50.2 5.1 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein Vps53_N PF04100.7 EDN08347.1 - 3.7e-105 351.8 4.0 7.7e-105 350.8 2.8 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal LRR_4 PF12799.2 EDN08347.1 - 3.5e-08 32.8 10.3 4.7e-07 29.2 0.7 2.9 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 EDN08347.1 - 1.5e-07 31.7 0.0 1.4e-06 28.6 0.0 2.7 3 0 0 3 3 3 1 Nuclear transport factor 2 (NTF2) domain TAP_C PF03943.8 EDN08347.1 - 6.1e-07 28.7 2.1 2.4e-06 26.8 0.5 2.4 2 0 0 2 2 2 1 TAP C-terminal domain DUF2450 PF10475.4 EDN08347.1 - 1.8e-06 27.1 9.2 1.8e-06 27.1 6.4 2.3 2 1 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EDN08347.1 - 4.4e-05 23.3 0.3 0.00017 21.4 0.2 2.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 LRR_8 PF13855.1 EDN08347.1 - 0.00062 19.4 1.3 0.0025 17.5 0.9 2.1 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 EDN08347.1 - 0.00092 18.9 0.4 0.8 9.9 0.0 3.3 2 0 0 2 2 2 1 Leucine Rich Repeat LRR_6 PF13516.1 EDN08347.1 - 0.0065 16.4 0.3 1.5 9.1 0.1 3.2 2 0 0 2 2 2 1 Leucine Rich repeat LRR_7 PF13504.1 EDN08347.1 - 0.0075 16.2 0.1 0.75 10.2 0.0 3.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_9 PF14580.1 EDN08347.1 - 0.024 14.1 0.1 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat DUF342 PF03961.8 EDN08347.1 - 0.25 9.7 2.6 0.71 8.2 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF342) COPIIcoated_ERV PF07970.7 EDN08348.1 - 3.1e-70 236.2 0.2 1.3e-46 159.0 0.0 2.1 1 1 1 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EDN08348.1 - 5.3e-33 112.8 0.0 3.9e-32 110.0 0.0 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) zf-C4H2 PF10146.4 EDN08350.1 - 1.9 8.4 6.3 1.2 9.1 2.2 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein PH PF00169.24 EDN08351.1 - 4.1e-06 26.9 0.0 2.3e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EDN08351.1 - 0.0001 22.4 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain zf-C2H2 PF00096.21 EDN08353.1 - 2.3e-24 84.2 57.2 0.0001 22.4 0.6 10.7 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN08353.1 - 1.2e-23 81.5 58.4 0.004 17.3 0.1 10.6 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDN08353.1 - 1.6e-17 62.8 55.0 4.5e-05 23.5 0.6 10.8 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EDN08353.1 - 6.3e-06 26.1 15.8 1.2 9.3 0.0 8.4 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 EDN08353.1 - 4.7e-05 22.8 0.2 4.7e-05 22.8 0.1 3.4 4 0 0 4 4 4 1 GAGA factor zf-met PF12874.2 EDN08353.1 - 0.046 13.9 20.9 0.3 11.3 0.1 8.0 9 0 0 9 9 9 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EDN08353.1 - 0.13 12.2 12.4 27 4.8 0.0 6.9 7 0 0 7 7 7 0 C2H2-type zinc finger RNA_pol_Rpb6 PF01192.17 EDN08354.1 - 1.3e-13 50.4 1.4 1.2e-08 34.5 0.1 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb6 RVT_2 PF07727.9 EDN08356.1 - 5.9e-47 159.6 0.0 8.7e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DEAD PF00270.24 EDN08358.1 - 1.8e-11 43.8 0.0 3.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN08358.1 - 0.0002 21.2 0.0 0.00042 20.1 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDN08358.1 - 0.12 12.5 0.0 0.31 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain MOZART1 PF12554.3 EDN08359.1 - 0.24 10.9 1.1 6.7 6.2 0.1 2.3 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated Tom37_C PF11801.3 EDN08359.1 - 0.43 10.4 1.9 3.5 7.4 1.3 2.3 1 1 0 1 1 1 0 Tom37 C-terminal domain Acetyltransf_1 PF00583.19 EDN08363.1 - 0.022 14.8 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EDN08363.1 - 0.065 13.0 0.0 0.079 12.8 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EDN08363.1 - 0.069 13.3 0.1 0.082 13.0 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Myb_DNA-binding PF00249.26 EDN08365.1 - 0.0005 20.0 0.1 0.0011 18.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF573 PF04504.9 EDN08365.1 - 0.0014 18.8 0.7 0.0043 17.3 0.5 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF573 Myb_DNA-bind_6 PF13921.1 EDN08365.1 - 0.004 17.2 1.1 0.0088 16.1 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDN08365.1 - 0.037 14.1 2.3 0.48 10.5 1.6 2.4 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DEAD PF00270.24 EDN08367.1 - 2.7e-16 59.5 0.0 1.4e-15 57.2 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN08367.1 - 1.1e-15 57.2 0.1 3.3e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN08367.1 - 2.1e-07 30.9 0.1 2e-05 24.5 0.0 3.3 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDN08367.1 - 0.013 14.3 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain KaiC PF06745.8 EDN08367.1 - 0.029 13.4 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 KaiC RVT_1 PF00078.22 EDN08368.1 - 2.3e-18 66.3 0.0 2.3e-13 50.0 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN08368.1 - 6e-16 58.1 0.0 1.8e-15 56.6 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN08368.1 - 7.3e-07 29.3 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Myb_DNA-binding PF00249.26 EDN08369.1 - 0.00039 20.4 0.1 0.00084 19.3 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF573 PF04504.9 EDN08369.1 - 0.0011 19.2 0.7 0.0032 17.7 0.5 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF573 Myb_DNA-bind_6 PF13921.1 EDN08369.1 - 0.0025 17.8 1.0 0.0066 16.5 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDN08369.1 - 0.024 14.7 2.3 0.36 10.9 1.6 2.5 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF3505 PF12013.3 EDN08371.1 - 6.4e-16 58.5 0.2 7.9e-15 55.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) DUF4219 PF13961.1 EDN08372.1 - 0.0029 16.9 0.2 0.0057 16.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) DUF4219 PF13961.1 EDN08373.1 - 0.0055 16.1 0.2 0.013 14.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.18 EDN08373.1 - 1.4 8.9 4.3 2.4 8.2 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle P2X_receptor PF00864.14 EDN08375.1 - 0.042 12.5 0.6 0.066 11.9 0.4 1.3 1 0 0 1 1 1 0 ATP P2X receptor DDE_Tnp_1_7 PF13843.1 EDN08377.1 - 0.0017 17.4 0.0 0.0024 17.0 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 CEP44 PF15007.1 EDN08378.1 - 0.11 12.1 0.2 0.14 11.8 0.2 1.1 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 RVT_1 PF00078.22 EDN08379.1 - 2.1e-28 99.1 0.0 3.5e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN08379.1 - 6.6e-15 55.6 0.0 1.6e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN08379.1 - 2.1e-13 49.8 0.0 4.6e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Nol1_Nop2_Fmu PF01189.12 EDN08381.1 - 2.5e-94 315.7 0.0 4.3e-94 315.0 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family RVT_2 PF07727.9 EDN08381.1 - 2.6e-58 196.8 0.0 4.3e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN08381.1 - 2.8e-15 56.4 0.0 7.5e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 EDN08381.1 - 0.00029 20.6 4.1 0.00059 19.6 2.8 1.6 1 0 0 1 1 1 1 Zinc knuckle FtsJ PF01728.14 EDN08381.1 - 0.0014 18.6 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase gag_pre-integrs PF13976.1 EDN08381.1 - 0.0022 17.6 0.0 0.0072 15.9 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain APH PF01636.18 EDN08382.1 - 6.1e-20 71.9 0.0 8.2e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN08382.1 - 1.8e-05 24.4 0.0 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EDN08383.1 - 3.9e-07 29.4 0.7 7.3e-07 28.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 EDN08383.1 - 0.00023 20.2 0.0 0.00047 19.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN08383.1 - 0.0037 17.0 0.1 0.0037 17.0 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDN08383.1 - 0.13 11.5 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Mnd1 PF03962.10 EDN08383.1 - 1.2 8.7 8.4 2.8 7.5 5.8 1.6 1 0 0 1 1 1 0 Mnd1 family OmpH PF03938.9 EDN08383.1 - 1.2 9.0 8.2 2.6 7.9 5.7 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FemAB PF02388.11 EDN08383.1 - 4.6 5.8 7.4 7.8 5.0 5.2 1.2 1 0 0 1 1 1 0 FemAB family DUF4337 PF14235.1 EDN08383.1 - 9.9 5.9 7.1 18 5.1 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Myb_DNA-bind_6 PF13921.1 EDN08385.1 - 0.0021 18.1 0.1 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain FA_hydroxylase PF04116.8 EDN08386.1 - 3.4e-12 46.7 27.5 6.8e-12 45.7 16.9 2.5 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily UCH PF00443.24 EDN08388.1 - 1.4e-15 57.1 0.0 2.3e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MORN PF02493.15 EDN08388.1 - 2.5e-14 52.0 21.1 9.3e-06 25.0 0.1 4.7 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.1 EDN08388.1 - 2.2e-11 43.2 11.6 3.5e-11 42.5 8.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) USP7_ICP0_bdg PF12436.3 EDN08388.1 - 0.0025 17.1 0.0 0.0083 15.3 0.0 1.8 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 zf-C3HC4_2 PF13923.1 EDN08388.1 - 0.0034 17.3 13.4 0.006 16.5 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN08388.1 - 0.038 13.7 12.5 0.066 12.9 8.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Striatin PF08232.7 EDN08389.1 - 8.3e-48 162.1 3.8 8.3e-48 162.1 2.7 2.0 2 0 0 2 2 2 1 Striatin family WD40 PF00400.27 EDN08389.1 - 7.5e-33 111.2 14.3 1.1e-06 28.2 0.1 7.0 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EDN08389.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A XPA_C PF05181.7 EDN08390.1 - 1.4e-15 56.5 9.0 1.4e-13 50.1 6.2 2.6 1 1 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EDN08390.1 - 0.0029 17.2 2.0 0.0054 16.3 1.4 1.4 1 0 0 1 1 1 1 XPA protein N-terminal YhfH PF14149.1 EDN08390.1 - 0.018 14.8 1.7 4 7.3 0.0 2.6 2 0 0 2 2 2 0 YhfH-like protein zf-AD PF07776.10 EDN08390.1 - 0.23 11.4 2.6 0.24 11.4 0.7 1.9 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) PIG-P PF08510.7 EDN08391.1 - 1e-43 147.9 0.8 1e-43 147.9 0.5 2.1 2 0 0 2 2 2 1 PIG-P Myb_DNA-binding PF00249.26 EDN08393.1 - 1.7e-11 44.0 0.0 3.2e-07 30.2 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN08393.1 - 0.0048 16.9 1.2 0.12 12.4 0.0 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain DS PF01916.12 EDN08394.1 - 2.1e-78 263.5 0.2 1.6e-77 260.5 0.2 1.8 1 1 0 1 1 1 1 Deoxyhypusine synthase DUF544 PF04424.8 EDN08395.1 - 5.5e-09 35.8 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Gcd10p PF04189.8 EDN08396.1 - 5.1e-92 308.1 0.0 8.9e-92 307.4 0.0 1.4 1 0 0 1 1 1 1 Gcd10p family CBP PF12192.3 EDN08397.1 - 2e-16 59.6 0.0 4.7e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Fungal calcium binding protein MIT PF04212.13 EDN08397.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain RNase_H PF00075.19 EDN08398.1 - 1.1e-14 54.9 0.0 2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 RNase H FAM86 PF14904.1 EDN08400.1 - 0.07 12.8 0.0 0.077 12.7 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function MazG PF03819.12 EDN08400.1 - 0.11 12.4 0.1 0.12 12.3 0.0 1.0 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain CD52 PF15116.1 EDN08401.1 - 0.36 10.6 2.7 2.5 7.9 1.0 2.6 2 0 0 2 2 2 0 CAMPATH-1 antigen P21-Arc PF04062.9 EDN08402.1 - 1.2e-78 262.8 0.0 1.3e-78 262.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit AAA PF00004.24 EDN08403.1 - 2.8e-14 53.4 0.0 7.7e-14 52.0 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EDN08403.1 - 8.8e-13 48.0 0.0 2.3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EDN08403.1 - 1.9e-10 40.6 1.8 7.1e-09 35.5 0.0 2.8 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 EDN08403.1 - 1.3e-06 28.5 0.3 0.0075 16.4 0.0 2.7 2 1 1 3 3 3 2 AAA domain DNA_pol3_delta PF06144.8 EDN08403.1 - 7.4e-06 25.5 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.1 EDN08403.1 - 1.4e-05 24.7 0.0 3.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EDN08403.1 - 1.9e-05 24.7 0.2 0.0044 17.0 0.0 2.9 1 1 2 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 EDN08403.1 - 3e-05 23.6 0.3 0.00027 20.6 0.2 2.2 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EDN08403.1 - 3.1e-05 22.8 0.0 0.025 13.3 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus Rad17 PF03215.10 EDN08403.1 - 3.9e-05 22.5 0.0 0.087 11.4 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EDN08403.1 - 5.4e-05 23.1 0.0 9.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EDN08403.1 - 0.00017 21.2 0.0 0.00054 19.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EDN08403.1 - 0.00024 20.7 0.0 0.00047 19.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDN08403.1 - 0.00024 20.8 0.1 0.0011 18.7 0.1 2.1 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) DEAD PF00270.24 EDN08403.1 - 0.00059 19.3 0.1 0.0061 16.0 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_24 PF13479.1 EDN08403.1 - 0.00075 19.1 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDN08403.1 - 0.0015 17.9 0.3 0.0087 15.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EDN08403.1 - 0.0025 17.2 0.0 0.0088 15.4 0.0 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EDN08403.1 - 0.0028 16.7 0.5 0.027 13.5 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 EDN08403.1 - 0.006 15.8 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_17 PF13207.1 EDN08403.1 - 0.0063 17.3 0.0 0.012 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDN08403.1 - 0.012 15.9 0.0 0.029 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EDN08403.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EDN08403.1 - 0.02 14.3 0.2 1.9 7.8 0.1 2.4 1 1 0 1 1 1 0 AAA-like domain Mg_chelatase PF01078.16 EDN08403.1 - 0.032 13.4 0.1 0.32 10.1 0.0 2.4 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 EDN08403.1 - 0.045 13.2 0.0 0.43 10.0 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.10 EDN08403.1 - 0.049 13.4 0.0 2.8 7.7 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 EDN08403.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.8 EDN08403.1 - 0.14 11.0 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) His_Phos_2 PF00328.17 EDN08404.1 - 1.4e-10 41.0 0.0 2.5e-08 33.6 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Pro_isomerase PF00160.16 EDN08405.1 - 4.6e-37 127.6 0.0 9.8e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD R3H PF01424.17 EDN08406.1 - 3e-11 42.8 0.0 6.5e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EDN08406.1 - 1.3e-06 28.2 0.0 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN08406.1 - 8.9e-06 25.2 0.1 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN08406.1 - 0.024 14.4 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldo_ket_red PF00248.16 EDN08407.1 - 1.3e-22 79.9 0.0 1.9e-22 79.3 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family SANTA PF09133.5 EDN08407.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 SANTA (SANT Associated) HSF_DNA-bind PF00447.12 EDN08408.1 - 7.7e-15 54.9 0.2 1.7e-13 50.6 0.2 2.3 1 1 1 2 2 2 1 HSF-type DNA-binding TMF_DNA_bd PF12329.3 EDN08408.1 - 0.03 14.1 3.5 0.15 11.8 0.4 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CHD5 PF04420.9 EDN08408.1 - 0.4 10.3 0.7 1.2 8.8 0.5 1.7 1 0 0 1 1 1 0 CHD5-like protein Arb2 PF09757.4 EDN08409.1 - 1.9e-07 30.6 0.2 3.9e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Arb2 domain Luciferase_cat PF10285.4 EDN08409.1 - 0.15 11.1 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain Hist_deacetyl PF00850.14 EDN08410.1 - 2.1e-32 112.6 0.1 2.6e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain B-block_TFIIIC PF04182.7 EDN08410.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Gp_dh_C PF02800.15 EDN08411.1 - 2.2e-73 244.8 0.0 3.1e-73 244.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EDN08411.1 - 6.4e-61 204.7 0.3 1.3e-60 203.7 0.2 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EDN08411.1 - 0.039 13.8 0.9 0.14 12.0 0.0 2.3 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 EDN08411.1 - 0.064 12.8 0.1 0.22 11.0 0.0 1.8 1 1 1 2 2 2 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EDN08411.1 - 0.095 11.8 0.2 0.23 10.5 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pho88 PF10032.4 EDN08412.1 - 1.3e-56 190.8 0.0 1.3e-56 190.8 0.0 1.4 2 0 0 2 2 2 1 Phosphate transport (Pho88) DUF2576 PF10845.3 EDN08412.1 - 0.023 13.8 0.0 0.047 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Histone PF00125.19 EDN08415.1 - 9.8e-22 76.8 0.1 1.3e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDN08415.1 - 2.5e-06 27.4 0.0 3.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sugar_tr PF00083.19 EDN08417.1 - 6.8e-121 403.9 27.2 7.7e-121 403.7 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN08417.1 - 4.4e-21 74.9 44.2 4.6e-13 48.6 11.8 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3154 PF11351.3 EDN08417.1 - 0.036 13.7 1.4 0.11 12.2 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3154) DUF1469 PF07332.6 EDN08417.1 - 5.4 6.7 11.9 0.14 11.8 1.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) MFS_1 PF07690.11 EDN08418.1 - 3.2e-36 124.7 35.9 3.2e-36 124.7 24.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sigma_reg_N PF13800.1 EDN08418.1 - 5.6 7.0 6.7 91 3.1 0.7 3.8 3 0 0 3 3 3 0 Sigma factor regulator N-terminal zf-ZPR1 PF03367.8 EDN08419.1 - 1.2e-98 326.8 0.0 3.1e-48 163.0 0.0 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain KfrA_N PF11740.3 EDN08419.1 - 0.08 13.3 0.0 6 7.3 0.0 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Ima1_N PF09779.4 EDN08419.1 - 0.11 12.9 1.6 3.2 8.2 0.0 2.7 3 0 0 3 3 3 0 Ima1 N-terminal domain zf-H2C2_5 PF13909.1 EDN08419.1 - 1.3 9.4 4.6 21 5.5 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-ISL3 PF14690.1 EDN08419.1 - 2.2 8.3 5.5 17 5.5 0.2 3.3 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Pro_isomerase PF00160.16 EDN08420.1 - 6.4e-37 127.1 0.0 8.6e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.17 EDN08421.1 - 3.5e-16 59.5 0.1 1.3e-15 57.6 0.0 2.0 2 1 1 3 3 3 1 Arrestin (or S-antigen), C-terminal domain tRNA_int_end_N2 PF12928.2 EDN08423.1 - 7.8e-34 114.9 0.0 1.2e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EDN08423.1 - 0.0038 16.7 0.0 0.0091 15.5 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Skp1_POZ PF03931.10 EDN08424.1 - 3.3e-11 43.1 0.0 4.1e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain adh_short PF00106.20 EDN08425.1 - 5.5e-24 84.9 0.6 1.5e-11 44.4 0.3 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EDN08425.1 - 1.5e-09 37.9 1.1 2.9e-08 33.7 0.8 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN08425.1 - 6.7e-07 29.1 4.0 8.7e-06 25.5 0.1 3.2 2 2 1 3 3 3 1 KR domain Epimerase PF01370.16 EDN08425.1 - 0.0014 18.0 0.6 0.26 10.6 0.0 2.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EDN08425.1 - 0.0018 17.2 0.0 0.016 14.1 0.0 2.0 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EDN08425.1 - 0.003 17.6 0.2 0.017 15.2 0.0 2.2 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EDN08425.1 - 0.022 15.2 0.0 0.056 13.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EDN08425.1 - 0.022 14.7 0.9 0.13 12.2 0.0 2.4 3 0 0 3 3 3 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EDN08425.1 - 0.024 14.3 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.16 EDN08426.1 - 1.8e-37 128.2 0.0 4.3e-37 126.9 0.0 1.7 1 1 0 1 1 1 1 ThiF family UAE_UbL PF14732.1 EDN08426.1 - 9.7e-23 80.0 0.5 2.9e-22 78.5 0.3 1.9 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBACT PF02134.16 EDN08426.1 - 5.6e-16 57.8 2.7 2.2e-15 55.9 1.9 2.0 1 1 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein NAD_binding_7 PF13241.1 EDN08426.1 - 0.0044 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EDN08426.1 - 0.0054 16.8 0.1 0.022 14.8 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UBA_e1_thiolCys PF10585.4 EDN08426.1 - 0.027 13.8 1.5 0.074 12.4 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Pyr_redox PF00070.22 EDN08426.1 - 0.13 12.6 0.3 2.8 8.4 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF2419 PF10343.4 EDN08427.1 - 1.4e-136 454.4 0.0 1.7e-136 454.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Nucleoplasmin PF03066.10 EDN08427.1 - 0.045 13.2 2.7 0.085 12.3 1.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin Amidase PF01425.16 EDN08428.1 - 3.5e-90 302.9 0.0 4e-90 302.7 0.0 1.0 1 0 0 1 1 1 1 Amidase DNA_pol_delta_4 PF04081.8 EDN08429.1 - 1.1e-28 99.9 0.7 1.6e-28 99.4 0.5 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 DivIC PF04977.10 EDN08429.1 - 0.27 10.7 2.6 0.3 10.5 0.2 2.0 2 0 0 2 2 2 0 Septum formation initiator CAF-1_p150 PF11600.3 EDN08429.1 - 0.48 9.7 7.1 0.71 9.2 4.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CFEM PF05730.6 EDN08430.1 - 1.5e-15 56.7 10.7 2e-15 56.3 7.4 1.2 1 0 0 1 1 1 1 CFEM domain ATP-grasp_2 PF08442.5 EDN08434.1 - 1.6e-08 34.1 0.0 2.5e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding PF02629.14 EDN08435.1 - 2.1e-18 66.6 0.2 7.3e-18 64.8 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Citrate_synt PF00285.16 EDN08435.1 - 7e-18 64.4 0.0 3.2e-15 55.7 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 EDN08435.1 - 1.1e-14 54.3 0.1 1.9e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EDN08435.1 - 1e-06 28.4 0.0 2e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain RNase_P_Rpp14 PF01900.14 EDN08436.1 - 1.5e-10 40.9 0.0 2.5e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.12 EDN08437.1 - 4.3e-75 252.2 0.0 5.1e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 EDN08437.1 - 0.0004 19.2 0.0 0.00066 18.5 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_10 PF12846.2 EDN08437.1 - 0.0017 17.8 0.1 0.013 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 EDN08437.1 - 0.0024 17.3 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CbiA PF01656.18 EDN08437.1 - 0.005 16.2 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EDN08437.1 - 0.01 16.6 4.6 0.017 15.9 0.5 2.8 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EDN08437.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EDN08437.1 - 0.045 13.7 0.0 9.1 6.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EDN08437.1 - 0.066 12.4 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 EDN08437.1 - 0.09 12.7 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 EDN08437.1 - 0.12 12.2 0.0 0.65 9.9 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 EDN08437.1 - 0.14 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4631 PF15450.1 EDN08437.1 - 0.21 9.7 1.0 0.31 9.2 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) WD40 PF00400.27 EDN08438.1 - 6.2e-09 35.3 0.1 0.0006 19.5 0.1 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.27 EDN08439.1 - 1.6e-07 30.9 0.2 0.0001 22.0 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat Rib_5-P_isom_A PF06026.9 EDN08440.1 - 2e-37 128.1 0.0 2.2e-33 115.0 0.0 2.1 2 0 0 2 2 2 2 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EDN08440.1 - 0.068 12.8 0.0 5.7 6.5 0.0 2.1 2 0 0 2 2 2 0 DeoR C terminal sensor domain ThiF PF00899.16 EDN08441.1 - 9.3e-12 44.9 0.0 6.3e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 EDN08441.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 MoeZ/MoeB domain Cpn10 PF00166.16 EDN08444.1 - 6.7e-20 70.8 0.0 7.3e-20 70.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Phenyl_P_gamma PF09662.5 EDN08444.1 - 0.067 12.9 0.0 1.2 8.8 0.0 2.0 1 1 1 2 2 2 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) DUF3435 PF11917.3 EDN08446.1 - 2e-55 188.2 0.3 1.8e-45 155.4 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF3435) Phage_int_SAM_4 PF13495.1 EDN08446.1 - 0.00081 19.6 0.6 0.02 15.2 0.3 2.6 1 1 1 2 2 2 1 Phage integrase, N-terminal SAM-like domain DDE_1 PF03184.14 EDN08447.1 - 2.4e-50 170.6 0.0 6.2e-50 169.3 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4219 PF13961.1 EDN08447.1 - 0.014 14.7 0.2 0.031 13.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) DUF489 PF04356.7 EDN08448.1 - 0.0087 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF489) Fip1 PF05182.8 EDN08450.1 - 3.8e-22 77.2 2.3 6.8e-22 76.4 1.6 1.4 1 0 0 1 1 1 1 Fip1 motif CENP-T PF15511.1 EDN08450.1 - 0.036 13.3 14.3 0.052 12.7 9.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nucleoplasmin PF03066.10 EDN08450.1 - 0.8 9.2 8.8 1.4 8.4 6.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_60s PF00428.14 EDN08450.1 - 1.7 9.1 10.8 2.3 8.6 6.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein XAP5 PF04921.9 EDN08451.1 - 1.4e-57 194.9 0.0 5.5e-55 186.5 0.0 2.5 2 1 0 2 2 2 1 XAP5, circadian clock regulator DUF4604 PF15377.1 EDN08451.1 - 0.024 14.8 3.9 0.041 14.0 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Peptidase_C6 PF00851.13 EDN08452.1 - 0.02 13.5 0.1 0.025 13.2 0.0 1.1 1 0 0 1 1 1 0 Helper component proteinase DUF1031 PF06275.6 EDN08452.1 - 0.026 14.5 0.3 0.054 13.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) AhpC-TSA PF00578.16 EDN08452.1 - 0.099 12.3 0.2 0.22 11.1 0.1 1.4 1 1 0 1 1 1 0 AhpC/TSA family Nucleoporin_FG PF13634.1 EDN08453.1 - 8.2e-17 61.4 85.6 1.6e-12 47.6 28.0 2.8 1 1 1 2 2 2 2 Nucleoporin FG repeat region Prominin PF05478.6 EDN08453.1 - 0.047 11.2 0.1 0.71 7.3 0.0 2.0 2 0 0 2 2 2 0 Prominin Pectate_lyase_3 PF12708.2 EDN08454.1 - 3.2e-25 89.5 12.9 1.3e-08 35.2 1.1 3.5 2 1 1 3 3 3 3 Pectate lyase superfamily protein WD40 PF00400.27 EDN08455.1 - 3.2e-10 39.4 3.2 0.003 17.3 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Lactonase PF10282.4 EDN08455.1 - 0.035 13.1 0.0 0.096 11.7 0.0 1.7 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller TPR_11 PF13414.1 EDN08457.1 - 5.3e-14 51.6 2.4 4e-13 48.8 0.5 2.3 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EDN08457.1 - 2.5e-06 26.8 1.3 0.036 13.6 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDN08457.1 - 1.3e-05 25.0 1.1 2.9e-05 23.9 0.8 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDN08457.1 - 5.4e-05 22.7 1.3 0.21 11.6 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDN08457.1 - 0.00052 19.6 0.2 0.29 11.0 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EDN08457.1 - 0.0051 16.9 0.4 0.01 15.9 0.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Gag_p24 PF00607.15 EDN08457.1 - 0.0063 16.0 0.1 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) TPR_14 PF13428.1 EDN08457.1 - 1.5 9.6 7.7 3.2 8.6 0.0 4.2 5 1 2 7 7 7 0 Tetratricopeptide repeat HAD_2 PF13419.1 EDN08458.1 - 1.9e-13 51.0 0.0 3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN08458.1 - 1e-06 28.3 0.0 2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDN08458.1 - 3.3e-06 27.6 0.0 0.00011 22.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Abhydrolase_3 PF07859.8 EDN08459.1 - 3.4e-33 114.9 0.0 4.9e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EDN08459.1 - 2.8e-05 23.0 0.0 4.6e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family rve PF00665.21 EDN08461.1 - 4.6e-20 71.9 0.0 1.1e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EDN08461.1 - 6.4e-14 51.3 1.1 1.6e-13 50.1 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 EDN08461.1 - 0.0055 16.0 0.0 2.5 7.3 0.0 2.6 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Mtf2_C PF14061.1 EDN08461.1 - 0.03 14.2 0.7 0.11 12.3 0.1 2.1 1 1 1 2 2 2 0 Polycomb-like MTF2 factor 2 RVT_1 PF00078.22 EDN08462.1 - 5.8e-30 104.2 0.0 8.9e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN08462.1 - 2.5e-15 56.1 0.0 9.7e-15 54.2 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN08462.1 - 0.00047 20.1 0.0 0.00098 19.1 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Kdo PF06293.9 EDN08463.1 - 9.1e-05 21.6 0.1 0.00019 20.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EDN08463.1 - 0.012 15.1 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase OmpH PF03938.9 EDN08463.1 - 0.016 15.1 0.6 0.031 14.2 0.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RIO1 PF01163.17 EDN08463.1 - 0.017 14.4 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EDN08463.1 - 0.022 14.5 0.1 0.022 14.5 0.1 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Cytochrom_C_2 PF01322.15 EDN08463.1 - 0.047 14.2 0.2 0.12 12.9 0.1 1.7 1 0 0 1 1 1 0 Cytochrome C' GrpE PF01025.14 EDN08463.1 - 0.14 11.7 4.5 1.1 8.7 2.1 2.4 2 0 0 2 2 2 0 GrpE DUF390 PF04094.9 EDN08463.1 - 2 6.3 14.8 3.5 5.5 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF4192 PF13830.1 EDN08463.1 - 3.8 7.0 11.1 6.4 6.3 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) V-SNARE_C PF12352.3 EDN08464.1 - 0.041 13.9 0.1 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus DUF3112 PF11309.3 EDN08468.1 - 9.5e-51 171.7 3.5 9.5e-51 171.7 2.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) DUF1980 PF09323.5 EDN08468.1 - 0.24 11.1 6.0 0.19 11.4 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Phage_Gp23 PF10669.4 EDN08468.1 - 8.2 6.5 6.2 1.2 9.2 0.7 2.0 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) FAD_binding_4 PF01565.18 EDN08469.1 - 2e-26 92.1 0.7 4.4e-26 90.9 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EDN08469.1 - 4.4e-05 23.3 0.3 0.00035 20.4 0.1 2.2 2 0 0 2 2 2 1 Berberine and berberine like DUF2852 PF11014.3 EDN08469.1 - 0.11 12.4 0.1 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Metallophos PF00149.23 EDN08470.1 - 5.6e-44 149.9 0.9 7.1e-44 149.5 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PI31_Prot_N PF11566.3 EDN08471.1 - 5e-36 123.6 0.0 6.6e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EDN08471.1 - 6.5e-20 71.5 18.5 6.5e-20 71.5 12.8 2.7 3 0 0 3 3 3 1 PI31 proteasome regulator Sugar_tr PF00083.19 EDN08473.1 - 9.8e-115 383.6 25.9 1.8e-114 382.8 18.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN08473.1 - 9.4e-26 90.3 35.4 2.6e-19 69.1 9.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EDN08473.1 - 1.1 9.1 7.0 4.5 7.1 0.1 3.1 3 0 0 3 3 3 0 MFS_1 like family UvdE PF03851.9 EDN08476.1 - 1.6e-108 361.9 0.0 2e-108 361.5 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE Amino_oxidase PF01593.19 EDN08479.1 - 1.4e-48 166.1 2.9 6.8e-30 104.5 0.9 2.7 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EDN08479.1 - 1.9e-15 56.6 0.1 1.4e-14 53.8 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EDN08479.1 - 6.2e-06 26.4 0.5 4.1e-05 23.7 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN08479.1 - 4.6e-05 23.7 1.7 6.1e-05 23.3 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDN08479.1 - 0.0002 20.3 2.0 0.00041 19.3 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDN08479.1 - 0.00044 19.2 0.2 0.00064 18.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EDN08479.1 - 0.00059 18.4 0.2 0.00099 17.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EDN08479.1 - 0.00074 18.6 0.4 0.0011 18.0 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EDN08479.1 - 0.0016 17.5 0.1 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EDN08479.1 - 0.0023 16.8 0.1 0.0035 16.2 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EDN08479.1 - 0.0026 17.6 0.6 0.03 14.1 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EDN08479.1 - 0.011 15.4 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EDN08479.1 - 0.25 10.2 0.1 0.44 9.4 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Homeobox PF00046.24 EDN08480.1 - 1e-14 53.8 3.6 2.2e-14 52.7 2.5 1.6 1 0 0 1 1 1 1 Homeobox domain NmrA PF05368.8 EDN08481.1 - 2.1e-08 33.7 0.0 5.8e-08 32.2 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN08481.1 - 0.0014 18.6 0.0 0.003 17.5 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding FAD_binding_4 PF01565.18 EDN08482.1 - 5.7e-21 74.4 0.1 8.3e-21 73.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DSPn PF14671.1 EDN08484.1 - 7.9e-44 149.0 0.0 2.8e-40 137.5 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EDN08484.1 - 1.1e-17 63.8 0.0 4.3e-17 61.9 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDN08484.1 - 2e-06 27.3 0.0 6e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EDN08484.1 - 0.062 13.5 0.1 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EDN08484.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Pcc1 PF09341.5 EDN08485.1 - 3.7e-22 78.1 0.7 2.2e-21 75.6 0.5 2.0 1 1 0 1 1 1 1 Transcription factor Pcc1 TT_ORF2 PF02957.10 EDN08485.1 - 0.0076 16.9 1.7 0.011 16.4 1.2 1.1 1 0 0 1 1 1 1 TT viral ORF2 Myc_N PF01056.13 EDN08485.1 - 0.063 12.4 0.1 0.086 11.9 0.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Mito_fiss_reg PF05308.6 EDN08485.1 - 0.31 10.3 2.4 0.38 10.0 1.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Mucin PF01456.12 EDN08485.1 - 9.5 5.9 18.2 3.3 7.4 10.9 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Translin PF01997.11 EDN08486.1 - 8.8e-16 58.1 0.1 1.2e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Translin family HR1 PF02185.11 EDN08486.1 - 0.00036 20.2 0.3 0.0007 19.2 0.2 1.5 1 0 0 1 1 1 1 Hr1 repeat DUF3510 PF12022.3 EDN08486.1 - 0.095 12.8 0.1 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) PLAC9 PF15205.1 EDN08486.1 - 0.14 12.4 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Placenta-specific protein 9 GSHPx PF00255.14 EDN08487.1 - 5e-38 128.7 0.0 6.5e-38 128.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EDN08487.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 EDN08487.1 - 0.1 12.1 0.1 0.2 11.2 0.1 1.8 1 1 0 1 1 1 0 Redoxin DUF4174 PF13778.1 EDN08487.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) SCO1-SenC PF02630.9 EDN08487.1 - 0.12 11.9 0.0 0.7 9.4 0.0 2.1 2 1 0 2 2 2 0 SCO1/SenC Ribosomal_L22e PF01776.12 EDN08488.1 - 4.6e-41 139.3 0.3 6.5e-41 138.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal L22e protein family RNase_T PF00929.19 EDN08489.1 - 3.5e-11 43.6 0.0 1.4e-10 41.6 0.0 1.9 1 1 0 1 1 1 1 Exonuclease Hydrolase_6 PF13344.1 EDN08490.1 - 4.4e-22 77.8 0.0 7.6e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN08490.1 - 1.3e-10 40.8 0.0 8.7e-10 38.1 0.0 2.4 2 1 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EDN08490.1 - 0.027 14.6 0.0 5.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Pmp3 PF01679.12 EDN08491.1 - 5e-27 93.3 6.1 5.5e-27 93.2 4.3 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 EDN08491.1 - 6.7 6.4 6.7 0.72 9.5 1.1 1.8 2 0 0 2 2 2 0 Conserved TM helix ATP-synt_C PF00137.16 EDN08493.1 - 5.8e-33 112.6 28.9 2.1e-17 62.7 8.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ABA_GPCR PF12430.3 EDN08493.1 - 0.47 9.5 3.1 2.8 7.0 0.5 2.0 1 1 0 2 2 2 0 Abscisic acid G-protein coupled receptor Flavi_NS4A PF01350.12 EDN08493.1 - 0.65 9.5 6.1 0.23 10.9 1.8 1.8 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DDE_1 PF03184.14 EDN08495.1 - 1.9e-52 177.5 0.0 3.1e-52 176.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN08495.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-CCHC_6 PF15288.1 EDN08495.1 - 0.064 12.9 0.5 0.52 10.0 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle G-alpha PF00503.15 EDN08496.1 - 4.5e-104 348.2 0.1 1.6e-79 267.4 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.16 EDN08496.1 - 2e-14 53.2 0.7 9.4e-10 37.9 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDN08496.1 - 2.2e-06 27.0 0.3 0.014 14.5 0.1 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EDN08496.1 - 0.0058 17.1 0.0 0.5 10.8 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 EDN08496.1 - 0.011 16.1 0.0 0.017 15.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EDN08496.1 - 0.018 14.5 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDN08496.1 - 0.023 14.6 0.0 0.42 10.5 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EDN08496.1 - 0.028 13.9 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2231 PF09990.4 EDN08496.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) Nif11 PF07862.6 EDN08498.1 - 0.027 14.4 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function AIF_C PF14721.1 EDN08499.1 - 0.2 11.8 1.5 0.2 11.9 0.2 1.7 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Complex1_LYR_2 PF13233.1 EDN08499.1 - 2.3 8.7 7.2 5.7 7.4 5.0 1.7 1 1 0 1 1 1 0 Complex1_LYR-like Spermine_synth PF01564.12 EDN08500.1 - 4e-97 323.9 0.0 5e-97 323.6 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EDN08500.1 - 0.00068 19.2 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN08500.1 - 0.0013 19.3 0.0 0.0023 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN08500.1 - 0.007 16.8 0.2 0.03 14.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.11 EDN08500.1 - 0.0083 15.1 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_2 PF00891.13 EDN08500.1 - 0.053 12.7 0.4 0.55 9.3 0.1 2.3 1 1 2 3 3 3 0 O-methyltransferase Methyltransf_4 PF02390.12 EDN08500.1 - 0.067 12.2 0.0 0.14 11.1 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_24 PF13578.1 EDN08500.1 - 0.1 13.4 0.0 0.27 12.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EDN08500.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Transketolase_N PF00456.16 EDN08501.1 - 9.1e-122 406.0 0.0 1.4e-121 405.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EDN08501.1 - 1.2e-45 155.1 0.0 2e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EDN08501.1 - 2e-13 50.3 0.0 5.4e-13 48.9 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EDN08501.1 - 1.8e-05 23.8 0.2 0.017 14.0 0.0 2.2 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EDN08501.1 - 0.0096 14.6 0.4 0.014 14.1 0.3 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Mur_ligase_C PF02875.16 EDN08501.1 - 0.12 12.4 0.1 0.66 10.0 0.0 2.2 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain RVT_1 PF00078.22 EDN08502.1 - 8.2e-35 120.1 0.0 1.6e-34 119.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN08502.1 - 2.1e-15 56.4 0.0 1e-14 54.1 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN08502.1 - 0.00055 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EDN08502.1 - 0.00057 19.6 4.1 0.00057 19.6 2.9 2.3 2 0 0 2 2 2 1 Zinc knuckle DUF837 PF05769.6 EDN08502.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF837) zf-CCHC_4 PF14392.1 EDN08502.1 - 1 9.0 12.8 3.3 7.4 1.0 2.7 1 1 1 2 2 2 0 Zinc knuckle rve PF00665.21 EDN08503.1 - 1.1e-05 25.4 0.0 1.5e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain rve PF00665.21 EDN08504.1 - 4.3e-13 49.4 0.1 9.5e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN08504.1 - 1.7e-10 40.3 0.6 4.4e-10 39.0 0.4 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain RNase_H PF00075.19 EDN08505.1 - 2.4e-15 57.0 0.0 3.9e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN08505.1 - 0.085 12.6 0.1 0.3 10.9 0.1 1.9 1 1 0 1 1 1 0 Reverse transcriptase-like Fungal_trans PF04082.13 EDN08508.1 - 5.2e-30 104.1 0.2 1.1e-29 103.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN08508.1 - 2.2e-08 33.8 14.7 3.8e-08 33.0 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.23 EDN08509.1 - 0.09 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 SET domain MMR_HSR1_C PF08438.5 EDN08511.1 - 9.4e-32 109.4 0.0 1.8e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EDN08511.1 - 9.7e-12 44.8 0.0 3.4e-11 43.1 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 EDN08511.1 - 0.0023 17.0 0.0 0.0045 16.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family ATP_bind_1 PF03029.12 EDN08511.1 - 0.0053 16.3 0.1 1 8.8 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EDN08511.1 - 0.0057 16.6 0.0 0.011 15.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 EDN08511.1 - 0.0096 15.7 0.1 0.95 9.2 0.0 2.9 3 0 0 3 3 3 1 Dynamin family FeoB_N PF02421.13 EDN08511.1 - 0.013 14.8 0.2 1.3 8.2 0.0 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B GTP_EFTU PF00009.22 EDN08511.1 - 0.022 14.2 0.2 0.56 9.6 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain ArgK PF03308.11 EDN08511.1 - 0.1 11.3 0.1 1.1 7.9 0.0 2.4 3 0 0 3 3 3 0 ArgK protein Ribosomal_L7Ae PF01248.21 EDN08512.1 - 1.6e-18 66.0 3.6 3.9e-18 64.7 0.9 2.5 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Peptidase_S46 PF10459.4 EDN08512.1 - 3.1 6.0 7.5 4 5.7 5.2 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF3824 PF12868.2 EDN08512.1 - 3.8 8.4 8.8 0.51 11.2 2.5 2.0 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) UcrQ PF02939.11 EDN08513.1 - 3.3e-27 94.1 0.1 4e-27 93.8 0.1 1.0 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.20 EDN08514.1 - 4.8e-25 88.5 7.3 5.8e-25 88.2 4.5 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family GatB_Yqey PF02637.13 EDN08514.1 - 0.071 12.8 0.5 0.12 12.0 0.4 1.5 1 0 0 1 1 1 0 GatB domain AA_permease PF00324.16 EDN08515.1 - 3.7e-104 348.7 41.1 2.1e-78 263.7 13.4 2.0 1 1 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EDN08515.1 - 2.6e-23 82.2 39.2 1e-16 60.5 14.7 2.1 2 0 0 2 2 2 2 Amino acid permease HTH_38 PF13936.1 EDN08516.1 - 1.9e-06 27.3 1.2 9.6e-06 25.0 0.4 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EDN08516.1 - 2.3e-05 23.8 0.6 0.00013 21.5 0.2 2.1 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EDN08516.1 - 0.00028 20.2 0.1 0.00095 18.5 0.0 1.9 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4 PF04545.11 EDN08516.1 - 0.067 12.5 0.2 0.15 11.4 0.2 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_28 PF13518.1 EDN08516.1 - 0.076 13.0 0.2 0.52 10.3 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain PAT1 PF09770.4 EDN08516.1 - 2.5 6.2 19.0 3.3 5.8 13.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cutinase PF01083.17 EDN08517.1 - 8.8e-39 133.0 0.0 1e-38 132.8 0.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EDN08517.1 - 0.0078 15.6 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF3115 PF11312.3 EDN08519.1 - 5.2e-80 268.6 0.0 1e-70 238.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3115) DUF938 PF06080.7 EDN08519.1 - 0.016 14.7 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF938) APH PF01636.18 EDN08521.1 - 5.8e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family NAD_synthase PF02540.12 EDN08522.1 - 4.6e-06 25.7 0.0 0.0014 17.5 0.0 2.2 2 0 0 2 2 2 2 NAD synthase CN_hydrolase PF00795.17 EDN08522.1 - 7.7e-05 22.1 0.1 0.003 16.9 0.0 2.3 1 1 1 2 2 2 2 Carbon-nitrogen hydrolase Phage_lysozyme PF00959.14 EDN08523.1 - 1.6e-15 57.3 0.0 3.2e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Phage lysozyme DUF382 PF04037.8 EDN08524.1 - 3.7e-62 207.8 1.4 5.9e-62 207.2 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 EDN08524.1 - 2.2e-21 74.9 6.3 2.2e-21 74.9 4.4 1.9 2 0 0 2 2 2 1 PSP YL1 PF05764.8 EDN08524.1 - 1.5 8.3 10.5 3.2 7.2 7.3 1.4 1 1 0 1 1 1 0 YL1 nuclear protein Myf5 PF12232.3 EDN08525.1 - 0.037 14.6 4.4 0.037 14.6 3.1 1.8 1 1 1 2 2 2 0 Myogenic determination factor 5 DUF202 PF02656.10 EDN08526.1 - 1.2e-22 79.8 4.6 1.2e-22 79.8 3.2 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF202) PTPA PF03095.10 EDN08527.1 - 1.8e-110 368.8 0.0 2.2e-110 368.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF1754 PF08555.5 EDN08528.1 - 2.4e-16 60.1 7.3 4e-16 59.4 5.0 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) SPX PF03105.14 EDN08528.1 - 0.013 15.2 2.3 0.016 15.0 1.6 1.0 1 0 0 1 1 1 0 SPX domain DegS PF05384.6 EDN08528.1 - 0.061 12.5 2.5 0.085 12.0 1.7 1.1 1 0 0 1 1 1 0 Sensor protein DegS Integrase_AP2 PF14657.1 EDN08528.1 - 0.42 10.4 0.1 0.42 10.4 0.1 3.0 3 1 1 4 4 4 0 AP2-like DNA-binding integrase domain zf-AN1 PF01428.11 EDN08529.1 - 1.4e-11 44.0 11.7 2.2e-11 43.4 8.1 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EDN08529.1 - 0.37 11.0 3.7 0.75 10.0 2.6 1.5 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain FeS PF04060.8 EDN08529.1 - 0.87 9.2 0.0 0.87 9.2 0.0 2.6 2 1 1 3 3 3 0 Putative Fe-S cluster Stc1 PF12898.2 EDN08531.1 - 0.00033 20.6 1.7 0.0014 18.6 0.5 2.2 2 0 0 2 2 2 1 Stc1 domain F-box PF00646.28 EDN08531.1 - 0.0067 16.0 0.7 0.014 15.0 0.1 1.9 2 0 0 2 2 2 1 F-box domain DZR PF12773.2 EDN08531.1 - 0.045 13.5 3.8 7.9 6.3 2.6 3.0 1 1 0 1 1 1 0 Double zinc ribbon F-box-like PF12937.2 EDN08531.1 - 0.069 12.8 0.3 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 F-box-like C1_4 PF07975.7 EDN08531.1 - 1.3 9.0 6.2 0.33 10.9 0.3 2.6 3 1 0 3 3 3 0 TFIIH C1-like domain DUF1752 PF08550.5 EDN08532.1 - 7.4e-14 51.0 5.3 1.5e-13 50.0 3.7 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AreA_N PF07573.6 EDN08532.1 - 0.00061 20.2 0.0 0.00061 20.2 0.0 4.2 3 1 1 4 4 4 1 Nitrogen regulatory protein AreA N terminus Zn_clus PF00172.13 EDN08535.1 - 0.053 13.4 5.0 0.084 12.8 3.5 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MADF_DNA_bdg PF10545.4 EDN08536.1 - 0.1 12.7 0.3 0.15 12.2 0.2 1.5 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DLH PF01738.13 EDN08537.1 - 9.7e-09 34.8 0.0 1.2e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EDN08537.1 - 0.019 14.7 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-C2H2 PF00096.21 EDN08538.1 - 8.9e-11 41.4 13.3 3.7e-05 23.8 0.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN08538.1 - 2e-09 37.1 8.7 2.1e-05 24.4 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDN08538.1 - 1.2e-08 34.8 9.7 4.4e-07 29.8 1.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.1 EDN08538.1 - 0.005 17.0 9.3 0.021 15.0 1.8 3.1 2 1 0 2 2 2 1 C2H2-type zinc-finger domain SprT-like PF10263.4 EDN08538.1 - 0.0051 16.4 0.2 0.008 15.8 0.2 1.3 1 0 0 1 1 1 1 SprT-like family zf-C2H2_jaz PF12171.3 EDN08538.1 - 0.0095 16.0 0.1 0.0095 16.0 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EDN08538.1 - 0.019 14.8 3.6 3.9 7.5 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EDN08538.1 - 0.78 9.4 4.2 0.18 11.4 0.5 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type K_channel_TID PF07941.6 EDN08538.1 - 2 8.7 5.2 0.31 11.2 0.5 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain zf-BED PF02892.10 EDN08538.1 - 4.1 7.2 7.5 0.52 10.1 0.5 2.6 2 0 0 2 2 2 0 BED zinc finger Pyridoxal_deC PF00282.14 EDN08539.1 - 3.5e-58 196.8 0.0 4.9e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EDN08539.1 - 0.0002 20.2 0.0 0.00033 19.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Fungal_trans_2 PF11951.3 EDN08540.1 - 6e-59 199.5 0.7 8.6e-59 199.0 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 EDN08541.1 - 2.5e-38 131.7 0.3 2.3e-37 128.5 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN08541.1 - 1.8e-20 73.1 0.1 2.8e-20 72.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EDN08541.1 - 3.4e-05 24.2 0.1 9.2e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EDN08541.1 - 8.4e-05 21.6 0.0 0.00018 20.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN08541.1 - 0.0011 18.7 4.1 0.35 10.5 0.0 3.6 2 1 2 4 4 4 2 Phosphotransferase enzyme family DUF1687 PF07955.6 EDN08542.1 - 1.1e-13 51.3 0.0 3.2e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) NAD_binding_2 PF03446.10 EDN08542.1 - 0.048 13.4 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Abhydrolase_2 PF02230.11 EDN08543.1 - 8e-44 149.6 0.0 1.3e-42 145.6 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EDN08543.1 - 3e-08 33.5 0.0 4.7e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDN08543.1 - 4.7e-06 25.9 0.0 0.0023 17.1 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EDN08543.1 - 5.6e-06 26.4 0.0 0.031 14.1 0.0 2.3 2 1 1 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EDN08543.1 - 4.6e-05 23.1 0.0 0.029 13.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 EDN08543.1 - 0.018 14.2 0.0 0.039 13.2 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EDN08543.1 - 0.053 13.0 0.0 6.3 6.2 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ctr PF04145.10 EDN08545.1 - 3.7e-34 117.8 0.2 4.2e-34 117.6 0.1 1.0 1 0 0 1 1 1 1 Ctr copper transporter family DUF2583 PF10762.4 EDN08545.1 - 0.1 12.7 2.0 0.17 12.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) FAD_binding_8 PF08022.7 EDN08546.1 - 2.6e-19 69.0 0.0 5e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EDN08546.1 - 1.1e-18 67.5 0.0 2e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EDN08546.1 - 5.2e-14 52.3 10.5 5.2e-14 52.3 7.3 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EDN08546.1 - 0.012 15.7 0.0 0.049 13.7 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain XPC-binding PF09280.6 EDN08546.1 - 0.083 12.3 1.0 0.16 11.4 0.7 1.4 1 0 0 1 1 1 0 XPC-binding domain DUF3273 PF11677.3 EDN08546.1 - 1.1 8.4 7.6 0.86 8.8 3.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3273) adh_short PF00106.20 EDN08548.1 - 1.3e-15 57.7 0.0 3.3e-14 53.1 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN08548.1 - 4.6e-06 26.4 0.0 7.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EDN08548.1 - 0.033 13.1 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Peptidase_S28 PF05577.7 EDN08548.1 - 0.14 10.6 0.0 0.27 9.7 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Epimerase PF01370.16 EDN08548.1 - 0.16 11.4 0.0 0.26 10.6 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAC PF01849.13 EDN08552.1 - 4.3e-21 74.1 0.2 7.1e-21 73.4 0.1 1.4 1 0 0 1 1 1 1 NAC domain Ank_2 PF12796.2 EDN08553.1 - 2.9e-12 46.7 0.1 9.2e-12 45.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Fungal_trans PF04082.13 EDN08553.1 - 3.9e-11 42.3 0.1 6.9e-11 41.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank PF00023.25 EDN08553.1 - 4.8e-08 32.4 2.0 0.011 15.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EDN08553.1 - 0.00057 20.0 0.3 0.087 13.1 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN08553.1 - 0.0007 20.0 0.2 0.024 15.1 0.1 3.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) zf-C2H2 PF00096.21 EDN08553.1 - 0.0014 18.8 1.3 0.0042 17.3 0.9 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN08553.1 - 0.0048 17.1 0.7 0.016 15.5 0.5 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger Lyase_N PF09092.6 EDN08553.1 - 0.018 14.6 0.1 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Lyase, N terminal Ank_3 PF13606.1 EDN08553.1 - 0.057 13.6 0.4 51 4.5 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat zf-met PF12874.2 EDN08553.1 - 0.083 13.1 0.2 0.25 11.5 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EDN08553.1 - 0.24 11.7 1.4 0.37 11.1 0.0 2.1 2 0 0 2 2 1 0 Zinc-finger double domain BTB PF00651.26 EDN08556.1 - 6.2e-23 80.8 0.1 8.2e-14 51.5 0.3 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank PF00023.25 EDN08556.1 - 9.4e-09 34.6 0.0 3.2e-06 26.6 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EDN08556.1 - 7.2e-08 32.6 0.0 1.9e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDN08556.1 - 7.6e-08 32.6 0.0 2.5e-07 31.0 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN08556.1 - 1.3e-05 25.2 0.1 5e-05 23.4 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN08556.1 - 5.9e-05 22.9 0.2 0.0035 17.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat YqzH PF14164.1 EDN08556.1 - 0.35 10.8 1.9 46 4.0 0.0 3.4 3 0 0 3 3 3 0 YqzH-like protein Pkinase PF00069.20 EDN08557.1 - 9e-56 188.9 0.1 2.6e-37 128.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN08557.1 - 7.4e-36 123.5 0.0 2e-25 89.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDN08557.1 - 0.0053 15.7 0.0 0.017 14.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Matrilin_ccoil PF10393.4 EDN08557.1 - 1.1 8.6 4.0 15 5.0 0.1 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Wbp11 PF09429.5 EDN08559.1 - 2.9e-25 88.0 14.5 5.2e-25 87.2 10.1 1.4 1 0 0 1 1 1 1 WW domain binding protein 11 DUF2365 PF10157.4 EDN08560.1 - 0.0052 16.6 2.0 0.0068 16.3 1.4 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) BBP1_C PF15272.1 EDN08560.1 - 0.029 13.9 3.0 0.042 13.4 2.1 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF310 PF03750.8 EDN08560.1 - 0.031 14.4 0.5 0.069 13.3 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF310) Perilipin PF03036.11 EDN08560.1 - 0.045 12.5 0.1 0.053 12.3 0.1 1.2 1 0 0 1 1 1 0 Perilipin family GvpL_GvpF PF06386.6 EDN08560.1 - 0.069 12.7 1.2 0.094 12.2 0.9 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF HrpJ PF07201.6 EDN08560.1 - 0.079 12.9 2.4 2.7 7.9 0.1 2.4 1 1 0 2 2 2 0 HrpJ-like domain Syntaxin PF00804.20 EDN08560.1 - 0.091 12.9 1.5 3.4 7.8 0.0 2.4 1 1 1 2 2 2 0 Syntaxin THOC7 PF05615.8 EDN08560.1 - 0.094 12.9 3.0 0.22 11.8 2.0 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 DUF745 PF05335.8 EDN08560.1 - 0.13 11.7 2.3 0.16 11.4 0.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) RasGAP_C PF03836.10 EDN08560.1 - 0.17 11.5 4.4 0.27 10.9 3.1 1.3 1 0 0 1 1 1 0 RasGAP C-terminus ING PF12998.2 EDN08560.1 - 0.19 11.9 4.3 0.15 12.3 0.5 2.1 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Snapin_Pallidin PF14712.1 EDN08560.1 - 0.55 10.5 4.8 2.9 8.2 0.6 2.2 1 1 1 2 2 2 0 Snapin/Pallidin IncA PF04156.9 EDN08560.1 - 1.1 8.8 6.3 3.4 7.2 4.3 1.6 1 1 1 2 2 2 0 IncA protein Rpr2 PF04032.11 EDN08561.1 - 1.2e-29 101.9 2.3 2.8e-29 100.8 1.6 1.6 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Lar_restr_allev PF14354.1 EDN08561.1 - 0.19 12.0 1.1 1.3 9.4 0.8 2.2 1 1 0 1 1 1 0 Restriction alleviation protein Lar DEAD PF00270.24 EDN08562.1 - 2.6e-34 118.1 0.0 4.7e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN08562.1 - 5.7e-24 83.7 0.0 5e-23 80.7 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN08562.1 - 1.6e-05 24.8 0.0 3.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EDN08562.1 - 0.014 14.4 0.0 0.033 13.2 0.0 1.5 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit ApbA PF02558.11 EDN08563.1 - 8.3e-26 90.2 0.0 1.2e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EDN08563.1 - 1.9e-25 89.2 0.0 3e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DASH_Hsk3 PF08227.6 EDN08564.1 - 2.8e-19 69.0 2.6 5.9e-19 67.9 1.8 1.6 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like FAM196 PF15265.1 EDN08564.1 - 0.019 14.2 7.9 0.024 13.8 5.5 1.0 1 0 0 1 1 1 0 FAM196 family DUF3822 PF12864.2 EDN08564.1 - 0.037 13.2 1.0 0.047 12.9 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) Filament PF00038.16 EDN08564.1 - 0.12 11.7 3.7 0.16 11.3 2.5 1.0 1 0 0 1 1 1 0 Intermediate filament protein Menin PF05053.8 EDN08564.1 - 0.18 9.9 5.3 0.21 9.7 3.7 1.1 1 0 0 1 1 1 0 Menin Miff PF05644.6 EDN08564.1 - 0.45 10.1 4.9 0.57 9.7 3.4 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Myc_target_1 PF15179.1 EDN08564.1 - 0.53 9.8 9.2 0.67 9.5 6.4 1.1 1 0 0 1 1 1 0 Myc target protein 1 Paramyxo_C PF01692.13 EDN08564.1 - 0.74 9.4 4.7 0.95 9.0 3.2 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Vac7 PF12751.2 EDN08564.1 - 0.91 8.2 7.8 1.1 8.0 5.4 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Peptidase_S64 PF08192.6 EDN08564.1 - 2.6 6.2 8.3 3.1 6.0 5.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF605 PF04652.11 EDN08564.1 - 4.5 6.5 15.7 5 6.4 10.9 1.0 1 0 0 1 1 1 0 Vta1 like DUF3984 PF13136.1 EDN08564.1 - 5 6.2 14.2 6.7 5.8 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) RCR PF12273.3 EDN08564.1 - 8.2 7.0 13.6 11 6.6 9.5 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Lin-8 PF03353.10 EDN08564.1 - 8.8 5.5 9.5 11 5.1 6.6 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist His_Phos_1 PF00300.17 EDN08565.1 - 1e-24 87.3 0.1 1.6e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Lipase_3 PF01764.20 EDN08566.1 - 3.9e-17 62.1 0.0 1.4e-14 53.8 0.0 2.5 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EDN08566.1 - 0.024 14.3 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family RGS PF00615.14 EDN08567.1 - 7.7e-09 35.6 0.1 1.9e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF3649 PF12365.3 EDN08567.1 - 0.034 13.6 1.2 0.034 13.6 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) T4_deiodinase PF00837.12 EDN08567.1 - 0.11 11.5 0.1 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Iodothyronine deiodinase DUF4231 PF14015.1 EDN08567.1 - 0.6 10.1 5.0 0.21 11.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) SecE PF00584.15 EDN08567.1 - 1.2 8.8 3.7 3.7 7.2 2.6 1.8 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex SMC_N PF02463.14 EDN08568.1 - 1.2e-17 63.8 0.4 1.6e-12 47.1 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EDN08568.1 - 1e-05 25.9 11.6 1e-05 25.9 8.0 5.7 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EDN08568.1 - 0.0013 18.7 1.0 0.38 10.6 0.3 2.6 2 0 0 2 2 2 2 AAA domain AAA_13 PF13166.1 EDN08568.1 - 0.028 12.8 48.7 0.7 8.2 0.0 4.4 3 1 1 4 4 4 0 AAA domain AAA_29 PF13555.1 EDN08568.1 - 0.098 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EDN08568.1 - 0.32 10.1 8.3 2 7.5 0.4 3.6 2 1 2 4 4 4 0 Reovirus sigma C capsid protein AKNA PF12443.3 EDN08568.1 - 0.6 10.1 17.2 0.46 10.5 1.7 4.6 1 1 2 4 4 4 0 AT-hook-containing transcription factor ABC_tran PF00005.22 EDN08568.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.5 4 2 0 4 4 4 0 ABC transporter Flu_NS2 PF00601.14 EDN08568.1 - 9.7 6.4 9.0 2.7 8.2 0.1 3.6 4 0 0 4 4 4 0 Influenza non-structural protein (NS2) AdoMet_MTase PF07757.8 EDN08569.1 - 4.2e-34 117.0 0.0 1.6e-33 115.1 0.0 2.0 2 1 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase DUF3237 PF11578.3 EDN08570.1 - 8.2e-37 125.8 0.0 1.2e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 EDN08570.1 - 2.5e-07 30.3 2.9 0.007 16.0 0.3 2.4 2 0 0 2 2 2 2 BED zinc finger Herpes_capsid PF06112.6 EDN08570.1 - 0.075 13.0 18.4 3.4 7.7 12.4 2.8 2 1 0 2 2 2 0 Gammaherpesvirus capsid protein zf-C2H2_2 PF12756.2 EDN08570.1 - 0.26 11.4 7.5 4.3 7.5 0.5 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PAT1 PF09770.4 EDN08570.1 - 1 7.5 11.4 1.3 7.1 7.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gln-synt_C PF00120.19 EDN08571.1 - 1.2e-53 181.9 0.0 8.5e-52 175.8 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short PF00106.20 EDN08572.1 - 7.7e-28 97.4 0.9 1.1e-27 97.0 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN08572.1 - 7.5e-18 65.1 0.0 1e-17 64.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN08572.1 - 4.6e-11 42.7 0.7 7.7e-11 41.9 0.5 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EDN08572.1 - 0.00013 21.6 0.2 0.00024 20.7 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EDN08572.1 - 0.0044 15.9 0.0 0.0062 15.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_12 PF08242.7 EDN08572.1 - 0.044 14.2 0.0 0.081 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ldh_1_N PF00056.18 EDN08572.1 - 0.065 13.0 0.6 0.18 11.6 0.3 1.8 1 1 1 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EDN08572.1 - 0.069 12.1 0.1 0.092 11.7 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EDN08572.1 - 0.091 12.7 1.6 0.25 11.3 0.8 1.9 1 1 0 1 1 1 0 NADH(P)-binding Methyltransf_31 PF13847.1 EDN08572.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 EDN08572.1 - 0.14 11.9 1.7 0.7 9.7 0.2 2.4 2 1 1 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Rad21_Rec8_N PF04825.8 EDN08573.1 - 3e-32 110.8 0.1 1.2e-31 108.9 0.0 2.0 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EDN08573.1 - 0.0017 17.4 0.1 0.0037 16.4 0.1 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF619 PF04768.8 EDN08574.1 - 3.7e-51 172.9 0.0 6.9e-51 172.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EDN08574.1 - 4.8e-29 101.1 0.0 2.1e-28 99.0 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EDN08574.1 - 4.6e-23 82.0 0.1 1e-22 80.8 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family GFO_IDH_MocA PF01408.17 EDN08574.1 - 0.042 14.3 0.0 0.13 12.8 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EDN08574.1 - 0.059 13.2 0.0 0.17 11.7 0.0 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.16 EDN08575.1 - 5.8e-33 112.3 0.8 6.6e-33 112.1 0.5 1.0 1 0 0 1 1 1 1 Synaptobrevin GP41 PF00517.12 EDN08575.1 - 0.065 12.7 0.0 0.078 12.5 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Methyltransf_23 PF13489.1 EDN08576.1 - 1e-17 64.3 0.0 1.8e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN08576.1 - 4.1e-12 46.4 0.0 9.5e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN08576.1 - 1.4e-09 37.6 0.0 3.9e-08 33.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN08576.1 - 4.5e-08 33.6 0.0 8.7e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN08576.1 - 1.1e-07 32.2 0.0 2.1e-06 28.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN08576.1 - 7.2e-05 23.0 0.0 0.00021 21.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN08576.1 - 8e-05 22.6 0.0 0.00049 20.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN08576.1 - 0.00036 19.7 0.0 0.0032 16.6 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EDN08576.1 - 0.00084 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 EDN08576.1 - 0.0027 16.8 0.0 0.0059 15.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EDN08576.1 - 0.0045 16.3 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EDN08576.1 - 0.007 15.5 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EDN08576.1 - 0.0075 16.2 0.0 0.021 14.8 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase CMAS PF02353.15 EDN08576.1 - 0.011 14.8 0.0 0.024 13.6 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EDN08576.1 - 0.026 13.7 0.0 0.38 9.8 0.0 2.4 3 0 0 3 3 3 0 O-methyltransferase DUF938 PF06080.7 EDN08576.1 - 0.082 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Glyco_hydro_76 PF03663.9 EDN08578.1 - 1.6e-127 425.9 9.3 1.9e-127 425.6 6.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 CBP4 PF07960.6 EDN08579.1 - 4.4e-38 129.7 1.5 5.8e-38 129.3 1.0 1.0 1 0 0 1 1 1 1 CBP4 IncA PF04156.9 EDN08579.1 - 0.00085 18.9 0.9 0.001 18.7 0.6 1.1 1 0 0 1 1 1 1 IncA protein Trp_oprn_chp PF09534.5 EDN08579.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) APG6 PF04111.7 EDN08579.1 - 0.081 11.9 8.1 0.094 11.7 5.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4646 PF15496.1 EDN08579.1 - 0.085 12.9 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) Tmemb_161AB PF10268.4 EDN08579.1 - 0.14 10.6 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB DUF3513 PF12026.3 EDN08579.1 - 0.48 9.9 5.4 0.63 9.5 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Sel1 PF08238.7 EDN08580.1 - 5.4e-48 160.3 27.1 1.1e-09 38.6 0.4 7.9 8 0 0 8 8 8 7 Sel1 repeat TPR_20 PF14561.1 EDN08580.1 - 0.087 12.9 0.4 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDN08580.1 - 0.18 12.3 8.6 7.6 7.2 0.0 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat LigB PF02900.13 EDN08581.1 - 1.9e-43 148.4 0.1 2.5e-32 111.9 0.0 2.0 2 0 0 2 2 2 2 Catalytic LigB subunit of aromatic ring-opening dioxygenase L51_S25_CI-B8 PF05047.11 EDN08582.1 - 1.6e-11 43.7 0.0 2.1e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.8 EDN08583.1 - 2e-30 105.2 0.0 2.3e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) ADH_N PF08240.7 EDN08584.1 - 1.1e-26 92.7 3.1 2.3e-26 91.7 2.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN08584.1 - 2.5e-19 69.1 0.1 6.7e-19 67.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN08584.1 - 0.0011 19.8 0.0 0.0021 18.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EDN08584.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Malate_synthase PF01274.17 EDN08585.1 - 1.3e-233 775.7 0.0 1.5e-233 775.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Glyco_hydro_3 PF00933.16 EDN08586.1 - 5.3e-86 288.2 0.0 7.3e-86 287.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EDN08586.1 - 9e-51 172.5 0.1 1.9e-49 168.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EDN08586.1 - 6.6e-19 67.6 1.2 5.6e-18 64.6 0.8 2.2 1 1 0 1 1 1 1 Fibronectin type III-like domain AA_permease_2 PF13520.1 EDN08587.1 - 6.6e-49 166.5 50.8 7.8e-49 166.3 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN08587.1 - 6.5e-25 87.4 42.3 8.2e-25 87.0 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease ABC_tran PF00005.22 EDN08589.1 - 2.7e-47 160.5 0.1 9.3e-26 90.7 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EDN08589.1 - 1.9e-14 54.3 5.4 0.00028 20.9 1.1 4.1 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 EDN08589.1 - 1.9e-12 46.9 0.0 0.00084 18.6 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.19 EDN08589.1 - 6.7e-08 32.0 0.1 1.4e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.1 EDN08589.1 - 6.8e-08 33.0 0.2 0.00085 19.7 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EDN08589.1 - 3.3e-07 29.7 0.8 0.014 14.8 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EDN08589.1 - 2.4e-05 25.1 0.0 0.46 11.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EDN08589.1 - 3.6e-05 23.0 0.0 0.21 10.6 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 EDN08589.1 - 3.9e-05 22.9 0.2 0.11 11.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EDN08589.1 - 5.2e-05 23.0 0.0 0.61 10.0 0.0 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 EDN08589.1 - 7.6e-05 22.6 0.5 0.055 13.2 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function DUF87 Miro PF08477.8 EDN08589.1 - 9.2e-05 22.9 0.0 0.16 12.4 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EDN08589.1 - 0.00011 22.3 0.1 0.18 11.9 0.0 3.2 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 EDN08589.1 - 0.00011 22.1 0.0 0.47 10.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 EDN08589.1 - 0.00022 20.7 2.6 1 8.7 0.1 3.8 4 0 0 4 4 4 2 AAA-like domain RNA_helicase PF00910.17 EDN08589.1 - 0.0052 16.9 0.2 4.8 7.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 EDN08589.1 - 0.0056 16.3 0.6 0.38 10.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 EDN08589.1 - 0.0063 16.4 0.1 4.5 7.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 EDN08589.1 - 0.007 16.1 0.0 0.75 9.5 0.0 3.4 4 0 0 4 4 4 1 Dynamin family MobB PF03205.9 EDN08589.1 - 0.01 15.5 0.1 7.2 6.3 0.0 3.0 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.1 EDN08589.1 - 0.011 14.2 0.1 1.7 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EDN08589.1 - 0.015 15.2 0.0 0.61 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EDN08589.1 - 0.016 14.6 0.2 2.4 7.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family ArgK PF03308.11 EDN08589.1 - 0.022 13.5 0.6 5.6 5.6 0.0 2.5 2 0 0 2 2 2 0 ArgK protein AAA_25 PF13481.1 EDN08589.1 - 0.034 13.5 0.0 10 5.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EDN08589.1 - 0.035 14.4 0.8 7.6 6.8 0.0 3.1 2 1 0 2 2 2 0 AAA domain HEAT PF02985.17 EDN08589.1 - 0.064 13.3 1.0 63 4.0 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat ATP-synt_ab PF00006.20 EDN08589.1 - 0.094 12.2 0.0 16 4.9 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF3584 PF12128.3 EDN08589.1 - 0.27 8.5 2.4 2.7 5.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ICL PF00463.16 EDN08590.1 - 1.2e-195 650.7 0.1 1.3e-195 650.5 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EDN08590.1 - 1.7e-09 37.2 0.0 4.3e-09 35.9 0.0 1.6 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase Toxin_61 PF15538.1 EDN08590.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 61 Citrate_synt PF00285.16 EDN08591.1 - 1.2e-99 333.4 0.0 1.4e-99 333.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase DNA_pol_A_exo1 PF01612.15 EDN08592.1 - 1.3e-09 37.8 0.0 6.1e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 3'-5' exonuclease AMP-binding PF00501.23 EDN08593.1 - 4.1e-64 216.5 0.0 4.8e-33 114.1 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EDN08593.1 - 5.1e-10 40.1 0.2 1.2e-09 38.9 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1661 PF07877.6 EDN08593.1 - 0.12 11.8 0.1 0.37 10.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) Abhydrolase_6 PF12697.2 EDN08594.1 - 1.8e-22 80.3 0.0 2.4e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN08594.1 - 4e-12 46.1 0.0 5.8e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EDN08594.1 - 0.0018 17.9 0.0 0.027 14.0 0.0 2.3 2 1 0 2 2 2 1 Serine hydrolase Lipase_2 PF01674.13 EDN08594.1 - 0.014 14.7 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) Hydrolase_4 PF12146.3 EDN08594.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase MmgE_PrpD PF03972.9 EDN08595.1 - 1.2e-145 485.1 0.0 1.7e-145 484.6 0.0 1.2 1 0 0 1 1 1 1 MmgE/PrpD family DUF3356 PF11836.3 EDN08595.1 - 0.031 14.0 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3356) SET PF00856.23 EDN08596.1 - 2.4e-05 24.6 0.0 4.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 SET domain DNA_methylase PF00145.12 EDN08597.1 - 8.7e-38 130.2 0.0 2.1e-28 99.4 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase GATase_2 PF00310.16 EDN08598.1 - 1.8e-19 69.6 0.1 5.3e-16 58.2 0.0 2.5 2 1 1 3 3 3 2 Glutamine amidotransferases class-II Pribosyltran PF00156.22 EDN08598.1 - 4.1e-13 49.1 0.1 8.5e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_6 PF13522.1 EDN08598.1 - 1e-12 48.1 0.0 2.2e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EDN08598.1 - 3.9e-12 46.0 0.0 7.9e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EDN08598.1 - 2e-06 26.6 0.0 3.9e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Mt_ATP-synt_D PF05873.7 EDN08599.1 - 2.7e-18 66.1 0.6 3e-18 65.9 0.4 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Blt1 PF12754.2 EDN08599.1 - 0.083 12.4 0.6 0.099 12.2 0.4 1.2 1 0 0 1 1 1 0 Cell-cycle control medial ring component DUF4515 PF14988.1 EDN08599.1 - 0.13 11.8 3.0 3.3 7.3 2.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4515) Syntaxin PF00804.20 EDN08599.1 - 0.33 11.1 2.6 0.43 10.7 1.4 1.5 1 1 0 1 1 1 0 Syntaxin Tropomyosin_1 PF12718.2 EDN08599.1 - 1.1 9.0 6.3 7.6 6.3 1.2 2.4 1 1 0 2 2 2 0 Tropomyosin like NAC PF01849.13 EDN08600.1 - 4.6e-23 80.5 0.0 7.3e-23 79.8 0.0 1.3 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 EDN08600.1 - 0.015 15.0 0.1 0.042 13.7 0.1 1.8 1 0 0 1 1 1 0 UBA/TS-N domain DUF4407 PF14362.1 EDN08600.1 - 1.8 7.4 6.7 0.48 9.3 2.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Ribosomal_L14e PF01929.12 EDN08601.1 - 1.8e-26 92.2 0.7 2.5e-26 91.7 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 RGS PF00615.14 EDN08602.1 - 0.015 15.4 0.1 0.16 12.0 0.0 2.3 2 1 0 2 2 2 0 Regulator of G protein signaling domain MFS_1 PF07690.11 EDN08603.1 - 1e-21 77.0 35.0 5e-21 74.7 23.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EDN08604.1 - 1.3e-36 126.0 31.9 4.5e-25 88.1 7.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN08604.1 - 2.3e-14 52.8 15.3 2.7e-13 49.3 2.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Folate_carrier PF01770.13 EDN08604.1 - 3.5e-06 25.7 0.1 7.1e-06 24.7 0.1 1.5 1 0 0 1 1 1 1 Reduced folate carrier MFS_2 PF13347.1 EDN08604.1 - 6e-05 21.6 23.1 0.00082 17.8 4.6 3.7 2 2 2 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.2 EDN08604.1 - 0.0024 17.6 4.8 0.0082 15.9 0.1 3.2 3 0 0 3 3 3 1 MFS_1 like family SRP-alpha_N PF04086.8 EDN08606.1 - 1.6e-86 290.1 0.1 2.1e-86 289.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EDN08606.1 - 2.2e-49 167.5 0.0 4.2e-49 166.6 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EDN08606.1 - 2e-07 31.0 0.2 2e-07 31.0 0.1 2.6 3 0 0 3 3 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 EDN08606.1 - 4.3e-06 26.2 0.0 9.5e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EDN08606.1 - 4.5e-06 25.6 0.0 8.1e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_30 PF13604.1 EDN08606.1 - 0.0011 18.6 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN08606.1 - 0.0012 18.8 0.0 0.0036 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EDN08606.1 - 0.0022 17.7 0.1 0.0068 16.1 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EDN08606.1 - 0.035 13.5 0.0 0.094 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain Fer4_NifH PF00142.13 EDN08606.1 - 0.037 13.2 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MMR_HSR1 PF01926.18 EDN08606.1 - 0.046 13.6 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EDN08606.1 - 0.049 13.9 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter FAM60A PF15396.1 EDN08606.1 - 0.13 11.9 1.3 0.33 10.6 0.3 1.9 2 0 0 2 2 2 0 Protein Family FAM60A AAA_14 PF13173.1 EDN08606.1 - 0.14 12.0 0.7 0.95 9.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain YIF1 PF03878.10 EDN08607.1 - 7.9e-73 244.5 3.9 1e-72 244.1 2.7 1.1 1 0 0 1 1 1 1 YIF1 Phage_T7_tail PF03906.9 EDN08608.1 - 0.032 13.8 0.4 0.059 13.0 0.3 1.4 1 0 0 1 1 1 0 Phage T7 tail fibre protein Fungal_trans PF04082.13 EDN08609.1 - 7.2e-12 44.7 0.1 1.9e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Catalase PF00199.14 EDN08610.1 - 7.8e-161 535.0 0.8 1e-160 534.6 0.5 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EDN08610.1 - 2.5e-17 62.4 0.1 5.8e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EDN08610.1 - 1.2e-07 31.2 0.0 2.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Mpv17_PMP22 PF04117.7 EDN08613.1 - 2.8e-21 74.9 0.1 6.5e-21 73.7 0.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Polysacc_synt_C PF14667.1 EDN08613.1 - 0.041 13.6 1.5 0.14 11.9 0.5 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Rieske PF00355.21 EDN08614.1 - 3.3e-16 58.6 0.0 6.2e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.14 EDN08614.1 - 2.9e-12 46.6 2.2 3.1e-05 23.7 0.1 3.4 3 0 0 3 3 3 3 Ring hydroxylating alpha subunit (catalytic domain) RabGAP-TBC PF00566.13 EDN08615.1 - 9.2e-37 126.5 0.6 2e-36 125.5 0.5 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EDN08615.1 - 1.9e-07 30.5 0.0 7.8e-05 22.0 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3548) GAS2 PF02187.12 EDN08616.1 - 0.00027 20.6 0.1 0.00057 19.5 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain HTH_7 PF02796.10 EDN08618.1 - 1.5e-07 31.1 0.0 4.2e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.1 EDN08618.1 - 4.8e-07 29.9 0.0 1.2e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Winged helix-turn helix HTH_33 PF13592.1 EDN08618.1 - 1.7e-06 27.4 0.0 4.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EDN08618.1 - 2.2e-06 27.0 0.5 0.00017 21.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 EDN08618.1 - 4.9e-05 22.7 0.0 0.00065 19.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.1 EDN08618.1 - 0.00027 20.8 0.0 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.13 EDN08618.1 - 0.00061 19.4 0.0 0.00099 18.8 0.0 1.4 1 1 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.1 EDN08618.1 - 0.04 14.7 0.0 0.23 12.2 0.0 2.0 1 1 1 2 2 2 0 Homeodomain-like domain HTH_Tnp_IS630 PF01710.11 EDN08618.1 - 0.043 13.4 0.0 0.068 12.8 0.0 1.4 1 1 0 1 1 1 0 Transposase GerE PF00196.14 EDN08618.1 - 0.055 12.7 0.9 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Terminase_5 PF06056.7 EDN08618.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Trp_repressor PF01371.14 EDN08618.1 - 0.12 12.2 0.1 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Trp repressor protein Hus1 PF04005.7 EDN08619.1 - 9.3e-111 369.4 0.0 1e-110 369.2 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.2 EDN08620.1 - 2.8e-105 352.1 0.0 3.9e-105 351.6 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EDN08620.1 - 2.8e-33 114.3 0.1 4e-32 110.6 0.0 2.5 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.2 EDN08620.1 - 2.3e-26 93.1 27.7 6.8e-17 62.1 7.0 5.2 3 1 3 6 6 6 2 Vesicle coat trafficking protein Sec16 N-terminus TPR_19 PF14559.1 EDN08620.1 - 0.013 15.8 1.9 0.16 12.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.15 EDN08621.1 - 5.1e-17 61.6 0.0 1.2e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EDN08621.1 - 5.6e-14 53.0 0.0 2.8e-13 50.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDN08621.1 - 1.4e-09 38.4 0.0 3.2e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN08621.1 - 1.3e-05 25.0 0.0 4.3e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EDN08621.1 - 0.012 15.1 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3850 PF12961.2 EDN08621.1 - 0.034 14.1 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3850) Mso1_Sec1_bdg PF14475.1 EDN08622.1 - 2.2e-10 39.7 0.0 4.2e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.12 EDN08623.1 - 1.9e-32 112.1 0.7 3.4e-32 111.2 0.5 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 EDN08623.1 - 9.7e-25 86.6 17.9 9.7e-25 86.6 12.4 2.6 2 1 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 EDN08623.1 - 1.1e-07 31.3 16.9 1.5e-07 30.8 11.7 1.2 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 EDN08623.1 - 0.00043 18.3 30.5 0.00051 18.1 21.2 1.1 1 0 0 1 1 1 1 Nop14-like family Cut8_N PF14482.1 EDN08623.1 - 0.41 10.6 6.4 1.2 9.1 4.4 1.9 1 1 0 1 1 1 0 Cut8 proteasome-binding domain SGT1 PF07093.6 EDN08623.1 - 0.56 8.5 19.5 0.74 8.1 13.5 1.2 1 0 0 1 1 1 0 SGT1 protein CENP-T PF15511.1 EDN08623.1 - 0.91 8.7 23.8 1.5 7.9 16.5 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T DUF605 PF04652.11 EDN08623.1 - 4.6 6.5 8.5 6.6 6.0 5.9 1.1 1 0 0 1 1 1 0 Vta1 like Amidase PF01425.16 EDN08624.1 - 3e-94 316.3 0.0 3.8e-94 316.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Ldh_2 PF02615.9 EDN08625.1 - 4.2e-102 341.2 0.0 4.8e-102 341.1 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase DUF3402 PF11882.3 EDN08626.1 - 1.4e-164 548.0 0.0 1.8e-164 547.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EDN08626.1 - 3.5e-104 347.7 0.0 5.1e-104 347.2 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein Prok_Ub PF14454.1 EDN08626.1 - 0.043 13.4 0.1 0.84 9.3 0.0 2.8 2 0 0 2 2 2 0 Prokaryotic Ubiquitin PAP2 PF01569.16 EDN08627.1 - 6.7e-15 54.9 1.3 6.7e-15 54.9 0.9 1.8 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 EDN08627.1 - 0.0063 16.2 0.0 0.062 13.0 0.0 2.2 2 0 0 2 2 2 1 Divergent PAP2 family Virul_fac_BrkB PF03631.10 EDN08627.1 - 0.052 12.9 5.2 0.034 13.5 2.0 1.6 1 1 1 2 2 2 0 Virulence factor BrkB PAT1 PF09770.4 EDN08628.1 - 4.8 5.2 8.1 5.4 5.1 5.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CRT10 PF08728.5 EDN08629.1 - 1.2e-17 63.1 0.0 7.1e-09 34.2 0.0 2.3 2 0 0 2 2 2 2 CRT10 RRN3 PF05327.6 EDN08629.1 - 2.7 6.0 5.7 3.9 5.4 3.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 EDN08629.1 - 6.7 4.4 14.3 8.8 4.0 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EDN08629.1 - 7.8 5.6 15.1 15 4.7 10.5 1.4 1 0 0 1 1 1 0 SDA1 Glyco_hydro_63 PF03200.11 EDN08630.1 - 2.2e-230 766.6 0.0 1.3e-183 612.0 0.1 3.0 1 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EDN08630.1 - 0.004 15.8 0.2 0.048 12.3 0.0 2.2 2 0 0 2 2 2 1 Trehalase RVT_1 PF00078.22 EDN08631.1 - 3e-28 98.6 0.0 4.9e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN08631.1 - 4.1e-14 53.0 0.0 9.9e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN08631.1 - 3.3e-13 49.2 0.0 7.5e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Bac_DNA_binding PF00216.16 EDN08631.1 - 0.19 11.7 0.0 5.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial DNA-binding protein RVT_1 PF00078.22 EDN08633.1 - 2.4e-35 121.8 0.0 3.9e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN08633.1 - 3.8e-13 49.0 0.0 8e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN08633.1 - 1.3e-11 44.9 0.0 3.4e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 RNase H Bac_DNA_binding PF00216.16 EDN08633.1 - 0.18 11.8 0.0 5.8 7.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial DNA-binding protein Vps51 PF08700.6 EDN08634.1 - 0.0007 19.3 0.1 0.0042 16.8 0.0 2.4 1 0 0 1 1 1 1 Vps51/Vps67 GCR1_C PF12550.3 EDN08635.1 - 4.6e-22 77.6 0.1 9.7e-22 76.6 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF3716 PF12511.3 EDN08635.1 - 0.014 15.0 0.1 0.03 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) DUF1640 PF07798.6 EDN08636.1 - 7.4e-14 52.1 5.0 2e-13 50.7 3.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) Baculo_PEP_C PF04513.7 EDN08636.1 - 0.011 15.5 4.2 0.022 14.5 2.9 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ALMT PF11744.3 EDN08636.1 - 0.013 14.1 0.7 0.024 13.3 0.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Coat_F PF07875.7 EDN08636.1 - 0.13 12.4 0.6 0.33 11.1 0.4 1.6 1 0 0 1 1 1 0 Coat F domain IncA PF04156.9 EDN08636.1 - 2.8 7.5 9.9 8.7 5.8 7.0 1.7 1 1 1 2 2 2 0 IncA protein HEAT_2 PF13646.1 EDN08637.1 - 4.2e-11 42.9 3.5 0.0038 17.4 0.0 6.7 5 2 3 8 8 8 4 HEAT repeats HEAT PF02985.17 EDN08637.1 - 5.9e-08 32.1 11.2 0.85 9.8 0.0 9.0 11 0 0 11 11 11 3 HEAT repeat Vac14_Fab1_bd PF12755.2 EDN08637.1 - 0.052 13.9 0.0 4.1 7.8 0.0 3.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Arm PF00514.18 EDN08637.1 - 0.25 11.2 3.8 5 7.1 0.0 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Transcrip_reg PF01709.15 EDN08638.1 - 4.9e-53 179.6 0.1 6.4e-53 179.2 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator CENP-I PF07778.6 EDN08639.1 - 1.2e-77 261.3 0.1 1.6e-77 260.8 0.1 1.1 1 0 0 1 1 1 1 Mis6 Luciferase_N PF05295.6 EDN08639.1 - 0.085 12.6 0.0 0.28 11.0 0.0 1.8 1 1 1 2 2 2 0 Luciferase/LBP N-terminal domain CLPTM1 PF05602.7 EDN08640.1 - 2.5e-168 560.3 0.0 3e-168 560.0 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) adh_short PF00106.20 EDN08641.1 - 3.2e-12 46.7 0.0 9.1e-12 45.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN08641.1 - 2.1e-08 34.2 0.0 3.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN08641.1 - 0.0029 17.3 0.0 0.0099 15.5 0.0 1.9 2 1 0 2 2 2 1 KR domain ASXH PF13919.1 EDN08642.1 - 3.4e-43 146.7 0.4 5.2e-43 146.1 0.3 1.2 1 0 0 1 1 1 1 Asx homology domain Longin PF13774.1 EDN08643.1 - 1.2e-27 95.2 0.1 1.8e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EDN08643.1 - 1.4e-13 50.2 0.0 3.2e-13 49.0 0.0 1.6 2 0 0 2 2 2 1 Synaptobrevin TrbI_Ftype PF09677.5 EDN08643.1 - 0.043 13.6 0.5 0.28 11.0 0.1 2.0 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) Elong_Iki1 PF10483.4 EDN08644.1 - 2.7e-69 233.6 0.1 8.2e-35 120.5 0.1 2.0 1 1 1 2 2 2 2 Elongator subunit Iki1 DUF1777 PF08648.7 EDN08645.1 - 5.2e-26 91.4 40.8 5.2e-26 91.4 28.3 3.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 EDN08645.1 - 2.3 6.5 25.8 2.7 6.3 17.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 D123 PF07065.9 EDN08646.1 - 1.5e-93 313.1 0.0 3.6e-91 305.3 0.0 2.2 2 0 0 2 2 2 2 D123 ECH PF00378.15 EDN08647.1 - 2.5e-26 92.2 0.0 4.6e-26 91.4 0.0 1.4 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase family HTH_29 PF13551.1 EDN08648.1 - 1.3e-07 31.7 0.0 2.2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.10 EDN08648.1 - 1.6e-07 31.0 0.0 4.2e-07 29.7 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_33 PF13592.1 EDN08648.1 - 1.7e-06 27.4 0.0 4.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EDN08648.1 - 2.3e-06 27.0 0.5 0.00017 21.0 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.1 EDN08648.1 - 5.1e-05 22.7 0.0 0.00065 19.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.13 EDN08648.1 - 0.00012 21.8 0.0 0.00018 21.1 0.0 1.3 1 1 0 1 1 1 1 'Paired box' domain HTH_28 PF13518.1 EDN08648.1 - 0.00027 20.8 0.0 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EDN08648.1 - 0.0033 18.2 0.0 0.017 15.9 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_IS630 PF01710.11 EDN08648.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Transposase GerE PF00196.14 EDN08648.1 - 0.056 12.7 0.9 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Terminase_5 PF06056.7 EDN08648.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Trp_repressor PF01371.14 EDN08648.1 - 0.13 12.1 0.1 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Trp repressor protein Nop14 PF04147.7 EDN08649.1 - 0.00054 18.0 11.3 0.00054 18.0 7.8 1.1 1 0 0 1 1 1 1 Nop14-like family Spore_coat_CotO PF14153.1 EDN08649.1 - 0.0024 17.3 4.7 0.0024 17.3 3.3 1.2 1 0 0 1 1 1 1 Spore coat protein CotO Daxx PF03344.10 EDN08649.1 - 0.0032 16.0 16.4 0.0037 15.8 11.4 1.1 1 0 0 1 1 1 1 Daxx Family Vfa1 PF08432.5 EDN08649.1 - 0.0039 17.2 3.9 0.005 16.8 2.7 1.3 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Nucleoplasmin PF03066.10 EDN08649.1 - 0.0042 16.6 15.1 0.0072 15.8 10.5 1.4 1 0 0 1 1 1 1 Nucleoplasmin DUF1510 PF07423.6 EDN08649.1 - 0.0099 15.2 9.8 0.012 14.9 6.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) BUD22 PF09073.5 EDN08649.1 - 0.014 14.4 8.0 0.012 14.6 5.5 1.1 1 0 0 1 1 1 0 BUD22 DUF3381 PF11861.3 EDN08649.1 - 0.019 14.4 14.4 1.9 7.9 9.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF4246 PF14033.1 EDN08649.1 - 0.026 13.1 5.0 0.029 13.0 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) TRAP_alpha PF03896.11 EDN08649.1 - 0.039 12.9 8.7 0.049 12.6 6.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ycf1 PF05758.7 EDN08649.1 - 0.069 10.8 4.6 0.067 10.9 3.2 1.0 1 0 0 1 1 1 0 Ycf1 Pox_Ag35 PF03286.9 EDN08649.1 - 0.095 12.2 9.8 0.12 11.8 6.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein YqfQ PF14181.1 EDN08649.1 - 0.11 12.5 7.2 0.16 11.9 5.0 1.4 1 0 0 1 1 1 0 YqfQ-like protein MYCBPAP PF14646.1 EDN08649.1 - 0.13 10.9 6.4 0.15 10.7 4.4 1.2 1 0 0 1 1 1 0 MYCBP-associated protein family CDC45 PF02724.9 EDN08649.1 - 0.14 10.1 10.3 0.15 10.0 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein IFT57 PF10498.4 EDN08649.1 - 0.17 10.5 5.4 0.18 10.4 3.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Paf1 PF03985.8 EDN08649.1 - 0.18 10.5 16.5 0.24 10.1 11.4 1.2 1 0 0 1 1 1 0 Paf1 Usp PF00582.21 EDN08649.1 - 0.18 11.9 1.4 0.25 11.5 1.0 1.4 1 0 0 1 1 1 0 Universal stress protein family eIF-3c_N PF05470.7 EDN08649.1 - 0.24 9.4 4.7 0.22 9.5 3.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2146 PF10220.4 EDN08649.1 - 0.28 9.1 1.8 0.31 8.9 1.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) SAPS PF04499.10 EDN08649.1 - 0.33 9.5 2.8 0.28 9.7 1.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sigma70_ner PF04546.8 EDN08649.1 - 0.34 10.5 16.1 0.54 9.8 11.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region PPP4R2 PF09184.6 EDN08649.1 - 0.45 10.0 19.7 0.67 9.4 13.7 1.3 1 0 0 1 1 1 0 PPP4R2 Herpes_gE PF02480.11 EDN08649.1 - 0.56 8.4 4.1 0.68 8.1 2.9 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RNA_pol_Rpc4 PF05132.9 EDN08649.1 - 0.59 10.1 9.0 1 9.3 6.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RNA_pol_3_Rpc31 PF11705.3 EDN08649.1 - 0.69 9.8 16.2 1.1 9.2 11.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIF_alpha PF05793.7 EDN08649.1 - 0.7 8.1 19.7 0.86 7.8 13.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM176 PF14851.1 EDN08649.1 - 0.99 9.0 10.9 1.7 8.3 7.5 1.4 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.6 EDN08649.1 - 1.1 6.9 7.8 1.4 6.6 5.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HSP90 PF00183.13 EDN08649.1 - 1.2 7.4 16.5 1.7 6.9 11.5 1.2 1 0 0 1 1 1 0 Hsp90 protein Tim54 PF11711.3 EDN08649.1 - 1.4 7.4 9.7 1.7 7.1 6.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GOLD_2 PF13897.1 EDN08649.1 - 1.6 8.9 4.1 2.1 8.5 2.9 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Prothymosin PF03247.9 EDN08649.1 - 1.7 8.8 32.6 3 8.0 22.6 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF2413 PF10310.4 EDN08649.1 - 2.3 6.9 11.1 3 6.5 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF4337 PF14235.1 EDN08649.1 - 3.5 7.4 4.7 4.5 7.0 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) XAP5 PF04921.9 EDN08649.1 - 4.1 6.9 9.8 5.5 6.4 6.8 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator DDHD PF02862.12 EDN08649.1 - 4.2 7.1 6.7 6 6.6 4.7 1.3 1 0 0 1 1 1 0 DDHD domain TLP-20 PF06088.6 EDN08649.1 - 4.4 6.9 6.1 6.9 6.3 4.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) VID27 PF08553.5 EDN08649.1 - 4.6 5.3 16.1 5.8 4.9 11.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein NESP55 PF06390.7 EDN08649.1 - 5.4 6.3 26.4 0.16 11.2 2.1 2.3 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) CobT PF06213.7 EDN08649.1 - 9.8 5.2 21.9 14 4.6 15.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2346 PF09803.4 EDN08650.1 - 0.0057 16.4 1.3 0.0095 15.7 0.9 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) DUF3317 PF11779.3 EDN08651.1 - 2.3e-23 81.3 4.0 3e-23 81.0 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) RF-1 PF00472.15 EDN08652.1 - 8e-24 83.6 4.1 1.2e-23 83.0 2.9 1.3 1 0 0 1 1 1 1 RF-1 domain Selenoprotein_S PF06936.6 EDN08652.1 - 0.15 11.6 8.7 0.21 11.1 6.1 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) Pox_Ag35 PF03286.9 EDN08652.1 - 0.2 11.1 9.9 0.26 10.7 6.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP_sp32 PF07222.7 EDN08652.1 - 8.5 5.4 8.6 10 5.1 6.0 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CAS_CSE1 PF03378.10 EDN08653.1 - 1.4e-186 620.0 0.0 4.9e-186 618.2 0.0 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EDN08653.1 - 1.1e-141 471.6 7.1 6.6e-140 465.8 3.3 2.4 2 1 0 2 2 2 1 Cse1 IBN_N PF03810.14 EDN08653.1 - 3.5e-13 49.2 0.0 1.7e-12 47.0 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EDN08653.1 - 0.088 12.7 0.5 3.8 7.4 0.0 3.7 4 1 0 4 4 4 0 Exportin 1-like protein DUF3384 PF11864.3 EDN08654.1 - 1.7e-100 336.7 2.6 3.2e-100 335.7 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EDN08654.1 - 1.6e-54 184.1 0.1 3e-54 183.2 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EDN08654.1 - 3.3e-18 65.9 3.2 6.5e-11 41.8 0.2 4.3 3 1 1 4 4 4 4 Tuberin PUF PF00806.14 EDN08655.1 - 7.1e-45 148.0 4.4 3.5e-08 32.4 0.0 6.8 7 0 0 7 7 7 6 Pumilio-family RNA binding repeat mit_SMPDase PF14724.1 EDN08655.1 - 0.075 10.8 0.1 0.12 10.2 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase p450 PF00067.17 EDN08658.1 - 9.5e-21 73.8 0.0 1.2e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4127 PF13552.1 EDN08658.1 - 0.081 11.3 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) p450 PF00067.17 EDN08659.1 - 2.3e-21 75.8 0.1 2.1e-20 72.7 0.1 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF912 PF06024.7 EDN08662.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Phosphodiest PF01663.17 EDN08663.1 - 1.4e-12 47.6 1.7 1.8e-12 47.2 0.3 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EDN08663.1 - 2.8e-06 26.9 0.7 4.7e-06 26.1 0.5 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EDN08663.1 - 1.5e-05 24.3 0.1 2.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase cwf21 PF08312.7 EDN08664.1 - 1.1e-15 57.1 13.4 1.1e-15 57.1 9.3 2.0 2 0 0 2 2 2 1 cwf21 domain PRP38_assoc PF12871.2 EDN08664.1 - 0.0046 17.4 25.1 0.0046 17.4 17.4 2.5 2 1 0 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1777 PF08648.7 EDN08664.1 - 1.1 8.9 38.3 0.067 12.9 17.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Helicase_C PF00271.26 EDN08665.1 - 6e-15 54.8 0.0 4.2e-14 52.1 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN08665.1 - 4.2e-11 42.6 0.2 2.6e-09 36.8 0.1 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EDN08665.1 - 5.3e-11 42.3 0.0 1.5e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EDN08665.1 - 6.3e-11 42.2 0.1 1.9e-10 40.6 0.1 1.9 1 1 0 1 1 1 1 Helicase associated domain (HA2) ResIII PF04851.10 EDN08665.1 - 9.2e-06 25.6 0.0 0.15 11.9 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDN08665.1 - 0.00011 22.2 0.0 0.00064 19.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EDN08665.1 - 0.0076 15.1 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EDN08665.1 - 0.018 14.6 0.2 0.062 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EDN08665.1 - 0.072 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EDN08665.1 - 0.11 12.1 2.3 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase HTH_7 PF02796.10 EDN08666.1 - 1.4e-07 31.2 0.0 3.7e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_29 PF13551.1 EDN08666.1 - 3.8e-07 30.2 0.0 1e-06 28.8 0.0 1.7 1 1 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EDN08666.1 - 1.2e-06 27.9 0.0 0.00015 21.2 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.1 EDN08666.1 - 2.3e-06 27.0 0.0 7.2e-06 25.4 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.1 EDN08666.1 - 4.1e-05 23.0 0.0 0.00057 19.3 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_28 PF13518.1 EDN08666.1 - 0.00022 21.1 0.0 0.018 15.0 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain PAX PF00292.13 EDN08666.1 - 0.0005 19.7 0.0 0.00083 19.0 0.0 1.4 1 1 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.1 EDN08666.1 - 0.031 15.0 0.0 0.2 12.4 0.0 2.0 1 1 1 2 2 2 0 Homeodomain-like domain GerE PF00196.14 EDN08666.1 - 0.037 13.3 0.2 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Terminase_5 PF06056.7 EDN08666.1 - 0.069 12.7 0.2 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_Tnp_IS630 PF01710.11 EDN08666.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Transposase Trp_repressor PF01371.14 EDN08666.1 - 0.1 12.5 0.1 0.23 11.4 0.0 1.5 2 0 0 2 2 2 0 Trp repressor protein MARVEL PF01284.18 EDN08667.1 - 1.5e-15 57.2 14.7 2.2e-15 56.7 10.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain Nucleoplasmin PF03066.10 EDN08667.1 - 0.0083 15.6 5.6 0.013 14.9 3.9 1.3 1 0 0 1 1 1 1 Nucleoplasmin FAM176 PF14851.1 EDN08667.1 - 0.02 14.5 0.3 0.032 13.9 0.2 1.3 1 0 0 1 1 1 0 FAM176 family DUF1510 PF07423.6 EDN08667.1 - 0.024 13.9 0.4 0.024 13.9 0.3 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF1510) Herpes_gE PF02480.11 EDN08667.1 - 0.035 12.3 0.0 0.048 11.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Fig1 PF12351.3 EDN08667.1 - 0.064 13.1 9.0 0.088 12.6 6.3 1.1 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 IFT57 PF10498.4 EDN08667.1 - 0.077 11.7 1.8 0.098 11.3 1.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TRAP_alpha PF03896.11 EDN08667.1 - 0.093 11.7 1.0 0.12 11.3 0.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit H_PPase PF03030.11 EDN08667.1 - 0.17 10.1 4.7 0.18 10.0 3.2 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase VID27 PF08553.5 EDN08667.1 - 0.26 9.4 3.0 0.32 9.1 2.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 EDN08667.1 - 0.55 8.1 2.1 0.69 7.8 1.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 EDN08667.1 - 1.5 8.3 9.0 2.2 7.8 6.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Ribosomal_60s PF00428.14 EDN08667.1 - 1.7 9.0 10.4 2.7 8.4 7.2 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein RXT2_N PF08595.6 EDN08667.1 - 2.4 7.9 6.0 3.4 7.4 4.2 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Myc_N PF01056.13 EDN08667.1 - 2.5 7.2 7.5 3.3 6.8 5.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region BSP_II PF05432.6 EDN08667.1 - 3.5 6.8 12.7 4.6 6.4 8.8 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) HSP90 PF00183.13 EDN08667.1 - 4 5.7 8.5 5.2 5.3 5.9 1.1 1 0 0 1 1 1 0 Hsp90 protein DUF3682 PF12446.3 EDN08667.1 - 4.3 7.6 12.0 6.2 7.1 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) CobT PF06213.7 EDN08667.1 - 8.4 5.4 12.1 12 4.9 8.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFIIF_alpha PF05793.7 EDN08667.1 - 8.8 4.5 12.0 11 4.1 8.3 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cohesin_load PF10345.4 EDN08669.1 - 8.8e-184 612.1 13.1 1.1e-183 611.7 9.1 1.1 1 0 0 1 1 1 1 Cohesin loading factor Lactamase_B_4 PF13691.1 EDN08669.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 tRNase Z endonuclease Histone PF00125.19 EDN08670.1 - 1.5e-28 98.6 0.1 2.2e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDN08670.1 - 0.00028 21.0 0.1 0.00039 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDN08670.1 - 0.018 15.0 0.6 0.033 14.2 0.4 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EDN08670.1 - 0.026 13.8 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DER1 PF04511.10 EDN08671.1 - 1.1e-41 142.5 7.9 1.3e-41 142.2 5.5 1.1 1 0 0 1 1 1 1 Der1-like family DUF4199 PF13858.1 EDN08671.1 - 0.074 12.9 1.1 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Serpentine_r_xa PF03383.10 EDN08671.1 - 0.087 12.5 1.1 0.13 11.9 0.8 1.3 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa EMP70 PF02990.11 EDN08672.1 - 1.8e-133 445.8 0.0 4.8e-133 444.3 0.0 1.7 1 1 0 1 1 1 1 Endomembrane protein 70 DUF3169 PF11368.3 EDN08672.1 - 2.9 7.0 8.9 2.5 7.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) ubiquitin PF00240.18 EDN08673.1 - 4.2e-18 64.4 0.0 7.1e-18 63.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EDN08673.1 - 3.6e-06 26.5 0.0 5.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDN08673.1 - 0.00017 21.6 0.0 0.00028 21.0 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EDN08673.1 - 0.003 17.4 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 EDN08673.1 - 0.032 14.8 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.1 EDN08673.1 - 0.098 12.9 0.1 0.85 9.9 0.1 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain CPSF_A PF03178.10 EDN08674.1 - 4.8e-101 338.0 0.0 1.5e-99 333.1 0.0 2.8 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EDN08674.1 - 8.6e-71 238.5 0.0 1.6e-70 237.7 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.1 EDN08674.1 - 0.029 13.9 0.0 2.7 7.6 0.0 3.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal WD40 PF00400.27 EDN08674.1 - 0.16 11.9 0.7 0.77 9.7 0.1 2.5 3 0 0 3 3 3 0 WD domain, G-beta repeat CN_hydrolase PF00795.17 EDN08675.1 - 7.3e-17 61.3 0.0 1.2e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Neisseria_TspB PF05616.8 EDN08675.1 - 1.4 7.2 7.9 2.2 6.5 5.5 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein BP28CT PF08146.7 EDN08676.1 - 1e-41 142.1 0.8 3.5e-41 140.4 0.5 2.0 1 0 0 1 1 1 1 BP28CT (NUC211) domain HEAT_2 PF13646.1 EDN08676.1 - 1.9e-05 24.8 5.1 0.037 14.2 0.1 5.3 5 2 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EDN08676.1 - 2.2 8.8 10.4 10 6.7 0.0 5.9 5 2 2 7 7 7 0 HEAT-like repeat U3snoRNP10 PF12397.3 EDN08677.1 - 2.4e-26 92.0 0.2 2.6e-25 88.7 0.0 2.7 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 EDN08677.1 - 0.00035 20.4 2.3 0.0029 17.5 0.1 3.5 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 EDN08677.1 - 0.00048 20.3 0.2 0.0018 18.5 0.0 2.0 2 0 0 2 2 2 1 HEAT repeats NRDE-2 PF08424.5 EDN08678.1 - 3.7e-61 206.7 0.5 3.2e-44 151.1 0.0 3.0 2 1 1 3 3 3 2 NRDE-2, necessary for RNA interference TPR_16 PF13432.1 EDN08678.1 - 0.0095 16.5 0.0 2.9 8.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDN08678.1 - 0.014 15.9 1.5 7.9 7.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat FAD_binding_8 PF08022.7 EDN08683.1 - 2.1e-22 78.9 0.0 4.6e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EDN08683.1 - 3.3e-20 72.5 0.0 5.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EDN08683.1 - 6.6e-17 61.7 10.7 6.6e-17 61.7 7.4 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EDN08683.1 - 0.0042 17.1 0.0 0.01 15.9 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EDN08683.1 - 0.087 13.4 0.0 2.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain SBDS PF01172.13 EDN08686.1 - 3.2e-25 87.7 0.1 4e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein NIR_SIR PF01077.17 EDN08686.1 - 0.015 14.6 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain VOMI PF03762.12 EDN08686.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) NB-ARC PF00931.17 EDN08686.1 - 0.13 11.1 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain RhoGEF PF00621.15 EDN08687.1 - 1.2e-10 41.5 0.2 7.9e-06 25.8 0.0 2.8 1 1 1 2 2 2 2 RhoGEF domain Ras PF00071.17 EDN08688.1 - 7.6e-27 93.6 1.2 7.4e-21 74.2 0.0 2.1 1 1 1 2 2 2 2 Ras family Miro PF08477.8 EDN08688.1 - 3e-09 37.4 1.2 0.002 18.5 0.1 2.5 2 1 1 3 3 3 2 Miro-like protein Pox_A32 PF04665.7 EDN08688.1 - 0.0082 15.4 0.4 0.013 14.7 0.2 1.3 1 1 0 1 1 1 1 Poxvirus A32 protein G-alpha PF00503.15 EDN08688.1 - 0.0094 14.6 0.3 0.66 8.5 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit ABC_tran PF00005.22 EDN08688.1 - 0.011 15.9 0.0 0.015 15.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 EDN08688.1 - 0.022 14.8 0.4 4.9 7.3 0.0 2.3 1 1 1 2 2 2 0 RNA helicase AAA_33 PF13671.1 EDN08688.1 - 0.033 14.0 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EDN08688.1 - 0.038 13.2 0.9 2 7.5 0.1 2.1 1 1 1 2 2 2 0 ADP-ribosylation factor family AAA_22 PF13401.1 EDN08688.1 - 0.045 13.8 0.2 0.15 12.1 0.1 1.8 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EDN08688.1 - 0.083 12.4 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EDN08689.1 - 1.1e-68 231.2 0.1 1.9e-68 230.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN08689.1 - 1.8e-11 43.7 0.0 4.5e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EDN08689.1 - 1.7e-07 30.8 5.2 3.1e-07 29.9 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EDN08689.1 - 4.6e-07 29.4 0.0 1.2e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 EDN08689.1 - 5.1e-06 26.4 8.6 1e-05 25.4 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN08689.1 - 0.00025 20.8 6.8 0.00052 19.7 4.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDN08689.1 - 0.00047 19.7 7.0 0.0012 18.4 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN08689.1 - 0.0058 16.3 7.0 0.014 15.1 4.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EDN08689.1 - 0.069 13.0 9.3 0.15 11.9 6.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RPM2 PF08579.6 EDN08689.1 - 0.092 12.8 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) APC_CDC26 PF10471.4 EDN08689.1 - 0.13 12.9 3.7 0.77 10.5 2.6 2.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 zf-RING_4 PF14570.1 EDN08689.1 - 0.83 9.2 6.8 2.2 7.9 4.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SR-25 PF10500.4 EDN08690.1 - 0.26 10.7 18.1 0.66 9.4 8.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SCP2 PF02036.12 EDN08691.1 - 7.4e-26 90.4 0.3 9.2e-26 90.1 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EDN08691.1 - 7.6e-09 35.6 0.1 9.3e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.1 EDN08691.1 - 0.047 13.0 0.0 0.055 12.8 0.0 1.1 1 0 0 1 1 1 0 Sterol carrier protein domain Ran_BP1 PF00638.13 EDN08692.1 - 5.1e-13 49.1 0.0 9.5e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 EDN08692.1 - 0.0023 18.1 30.5 0.0023 18.1 21.2 10.4 3 3 5 8 8 8 2 Nucleoporin FG repeat region Ribosomal_L31e PF01198.14 EDN08693.1 - 2.3e-38 129.7 1.2 2.9e-38 129.4 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.13 EDN08693.1 - 0.051 12.9 0.0 0.06 12.6 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel Glyco_transf_8 PF01501.15 EDN08694.1 - 2.1e-06 27.2 0.4 4.7e-06 26.1 0.3 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EDN08694.1 - 0.0024 17.2 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Abhydrolase_9 PF10081.4 EDN08694.1 - 0.1 11.2 0.1 0.18 10.5 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Aminotran_3 PF00202.16 EDN08695.1 - 1.3e-08 34.1 0.0 1.8e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EDN08695.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Hema_HEFG PF02710.9 EDN08695.1 - 0.063 13.5 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein RNA_pol_Rpb2_2 PF04561.9 EDN08695.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 Tyrosinase PF00264.15 EDN08697.1 - 3.6e-47 161.3 1.0 3.6e-47 161.3 0.7 1.8 2 0 0 2 2 2 1 Common central domain of tyrosinase Ank PF00023.25 EDN08698.1 - 1.2e-15 56.4 1.7 8.6e-09 34.7 0.4 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EDN08698.1 - 6.1e-13 48.9 1.4 2.7e-12 46.8 0.1 2.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EDN08698.1 - 1.3e-10 40.4 0.0 1.2e-05 25.0 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EDN08698.1 - 3e-10 40.0 0.1 6.2e-08 32.6 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN08698.1 - 1.3e-08 35.1 0.1 9.6e-08 32.3 0.1 2.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 EDN08699.1 - 1.5e-18 65.5 0.0 1.7e-05 24.3 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EDN08699.1 - 3.9e-17 62.3 0.0 1.6e-08 34.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDN08699.1 - 5.2e-14 52.3 0.0 3.9e-05 24.0 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN08699.1 - 4.8e-13 48.8 0.1 4.9e-06 26.6 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN08699.1 - 5.7e-12 44.6 0.0 0.002 18.2 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat ADH_zinc_N PF00107.21 EDN08700.1 - 9.5e-16 57.5 0.3 1.7e-15 56.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ATG2_CAD PF13329.1 EDN08702.1 - 6.4e-50 168.7 0.3 1.7e-49 167.3 0.2 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EDN08702.1 - 1.2e-27 95.9 0.0 3.2e-27 94.5 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain OAS1_C PF10421.4 EDN08702.1 - 0.66 9.4 0.5 1.4 8.3 0.4 1.4 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus AMP-binding PF00501.23 EDN08703.1 - 5e-44 150.3 0.0 8.5e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme A_deaminase PF00962.17 EDN08703.1 - 9.8e-36 123.3 0.0 1.5e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase AMP-binding_C PF13193.1 EDN08703.1 - 8.1e-18 65.1 0.6 2.7e-17 63.4 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF2841 PF11001.3 EDN08703.1 - 0.051 13.4 0.0 4.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2841) UQ_con PF00179.21 EDN08704.1 - 4.3e-49 165.5 0.0 5.2e-49 165.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDN08704.1 - 0.00038 20.2 0.0 0.0005 19.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDN08704.1 - 0.00065 19.5 0.1 0.00098 19.0 0.0 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EDN08704.1 - 0.0011 18.7 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.20 EDN08705.1 - 8.9e-34 116.8 0.0 3.6e-33 114.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN08705.1 - 5.5e-14 51.8 0.0 7.5e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN08705.1 - 3e-07 29.6 0.0 3.6e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EDN08705.1 - 0.0024 16.9 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN08705.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family APH PF01636.18 EDN08706.1 - 2.7e-09 37.0 0.1 5.4e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN08706.1 - 1.1e-06 28.4 0.0 2.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Phage_tail_U PF06141.6 EDN08706.1 - 0.033 14.2 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Phage minor tail protein U Pkinase PF00069.20 EDN08706.1 - 0.04 13.0 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DHBP_synthase PF00926.14 EDN08707.1 - 3.4e-70 235.2 0.0 1.1e-69 233.6 0.0 1.6 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase TFIIE_beta PF02186.10 EDN08708.1 - 2.4e-07 30.6 0.0 6.5e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 TFIIE beta subunit core domain RPA_C PF08784.6 EDN08708.1 - 0.047 14.1 0.8 0.67 10.4 0.0 2.7 3 0 0 3 3 3 0 Replication protein A C terminal RRM_3 PF08777.6 EDN08708.1 - 0.065 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif Pneumo_phosprot PF02478.11 EDN08708.1 - 0.28 10.6 2.7 0.44 10.0 1.9 1.3 1 0 0 1 1 1 0 Pneumovirus phosphoprotein TPR_MLP1_2 PF07926.7 EDN08709.1 - 2.9e-33 114.4 28.5 2.9e-33 114.4 19.7 16.8 7 5 8 15 15 15 5 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EDN08709.1 - 1.3e-05 25.0 26.0 0.00022 21.1 7.9 15.8 6 4 10 16 16 16 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 EDN08709.1 - 2.2e-05 23.1 4.7 2.2e-05 23.1 3.3 9.4 4 3 5 9 9 9 1 Weak chloroplast movement under blue light Filament PF00038.16 EDN08709.1 - 0.0003 20.3 22.9 0.0003 20.3 15.9 11.7 4 3 5 9 9 9 6 Intermediate filament protein MtrG PF04210.8 EDN08709.1 - 0.5 10.0 10.1 11 5.7 0.2 5.9 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G Hexapep PF00132.19 EDN08710.1 - 2.6e-07 29.8 16.9 0.0095 15.4 3.1 5.1 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EDN08710.1 - 0.64 9.6 12.6 0.74 9.4 2.2 3.8 2 2 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase LRR_6 PF13516.1 EDN08712.1 - 0.0016 18.3 0.1 1.9 8.7 0.0 3.9 4 0 0 4 4 4 1 Leucine Rich repeat LRR_8 PF13855.1 EDN08712.1 - 0.0023 17.6 0.2 0.082 12.6 0.0 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EDN08712.1 - 0.03 14.2 0.1 35 4.9 0.0 4.0 3 1 1 4 4 4 0 Leucine Rich Repeat Sec63 PF02889.11 EDN08713.1 - 2.2e-43 148.6 0.0 5.5e-43 147.3 0.0 1.7 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EDN08713.1 - 2.5e-16 59.6 0.1 5e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN08713.1 - 2.3e-08 33.7 0.0 5.6e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Nuc_sug_transp PF04142.10 EDN08715.1 - 1.5e-66 223.9 1.1 2e-66 223.5 0.8 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EDN08715.1 - 1.9e-05 24.8 14.8 0.00013 22.1 2.1 2.4 2 0 0 2 2 2 2 Multidrug resistance efflux transporter EamA PF00892.15 EDN08715.1 - 0.00059 19.8 8.9 0.00059 19.8 6.2 2.5 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.11 EDN08715.1 - 0.0014 18.3 20.2 0.076 12.6 2.7 3.1 2 1 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EDN08715.1 - 0.53 9.1 9.0 9 5.1 2.2 2.9 2 1 0 2 2 2 0 UAA transporter family HORMA PF02301.13 EDN08718.1 - 2.2e-42 144.8 0.0 4.3e-42 143.9 0.0 1.5 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 EDN08718.1 - 9.3e-05 22.0 6.7 0.00016 21.2 4.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EDN08718.1 - 0.019 14.2 3.1 0.075 12.3 2.1 1.9 1 1 0 1 1 1 0 PHD-finger Rrf2 PF02082.15 EDN08718.1 - 0.078 13.1 0.9 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator WD40 PF00400.27 EDN08719.1 - 2.1e-56 185.9 15.7 7.3e-09 35.1 0.0 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.28 EDN08719.1 - 5.6e-08 32.2 0.3 1.2e-07 31.1 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN08719.1 - 6.1e-08 32.2 0.1 1.4e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.1 EDN08719.1 - 0.17 11.3 2.0 3.8 6.8 1.3 2.6 1 1 0 1 1 1 0 PQQ-like domain MMR_HSR1 PF01926.18 EDN08720.1 - 3.6e-18 65.5 0.0 7.9e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDN08720.1 - 6.6e-07 29.2 0.4 0.017 14.9 0.1 2.7 3 0 0 3 3 3 2 Dynamin family AIG1 PF04548.11 EDN08720.1 - 4.9e-05 22.5 0.0 6.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EDN08720.1 - 0.00075 18.7 0.2 0.0017 17.5 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EDN08720.1 - 0.0034 16.6 0.0 0.0053 16.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EDN08720.1 - 0.0037 16.7 0.0 0.037 13.4 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EDN08720.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 EDN08720.1 - 0.034 13.4 0.0 0.06 12.6 0.0 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.13 EDN08720.1 - 0.098 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin Clat_adaptor_s PF01217.15 EDN08721.1 - 1.1e-38 132.2 0.0 1.9e-38 131.3 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L7Ae PF01248.21 EDN08722.1 - 1.8e-21 75.4 0.4 1.8e-21 75.4 0.3 1.8 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EDN08722.1 - 0.0067 16.2 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 CLASP_N PF12348.3 EDN08723.1 - 6.7e-05 22.3 0.2 0.00038 19.8 0.0 2.1 2 0 0 2 2 2 1 CLASP N terminal IncA PF04156.9 EDN08723.1 - 0.0026 17.3 5.1 0.0026 17.3 3.6 2.1 2 0 0 2 2 2 1 IncA protein HEAT_EZ PF13513.1 EDN08723.1 - 0.017 15.5 2.7 1.5 9.4 0.2 3.4 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.17 EDN08723.1 - 0.02 14.9 1.4 0.94 9.7 0.1 3.7 4 0 0 4 4 4 0 HEAT repeat Adaptin_N PF01602.15 EDN08723.1 - 0.021 13.1 0.0 0.05 11.9 0.0 1.5 1 0 0 1 1 1 0 Adaptin N terminal region TAN PF11640.3 EDN08723.1 - 0.035 13.8 0.0 0.16 11.6 0.0 2.2 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair DUF3584 PF12128.3 EDN08723.1 - 0.063 10.6 8.2 0.14 9.4 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TrmE_N PF10396.4 EDN08723.1 - 0.093 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 GTP-binding protein TrmE N-terminus MMS19_N PF14500.1 EDN08723.1 - 0.14 11.3 3.9 0.093 11.9 0.1 2.5 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Proteasom_PSMB PF10508.4 EDN08723.1 - 0.29 9.3 5.4 0.15 10.2 0.0 2.4 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit APG6 PF04111.7 EDN08723.1 - 0.52 9.2 18.2 0.12 11.3 9.4 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF641 PF04859.7 EDN08723.1 - 1.3 8.7 11.0 35 4.1 7.6 2.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.14 EDN08723.1 - 1.6 6.5 1.9 3 5.6 1.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EDN08723.1 - 4.4 7.6 8.4 17 5.8 5.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) ING PF12998.2 EDN08723.1 - 4.9 7.4 12.8 0.25 11.6 4.4 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ENTH PF01417.15 EDN08724.1 - 8.8e-50 167.7 0.0 1.4e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EDN08724.1 - 6.7e-05 21.7 0.0 0.00011 21.0 0.0 1.3 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.1 EDN08724.1 - 0.007 15.7 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) UIM PF02809.15 EDN08724.1 - 0.023 14.2 5.9 0.038 13.5 0.8 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif Csm1 PF12539.3 EDN08724.1 - 0.037 14.4 1.8 0.069 13.6 0.3 2.0 2 0 0 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 TSA PF03249.8 EDN08724.1 - 6.3 5.2 9.1 14 4.1 6.3 1.5 1 0 0 1 1 1 0 Type specific antigen Chorismate_bind PF00425.13 EDN08725.1 - 2.9e-89 298.7 0.0 4e-89 298.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EDN08725.1 - 2.3e-24 86.0 1.0 3.3e-21 75.7 0.0 3.4 2 1 0 2 2 2 2 Anthranilate synthase component I, N terminal region ATG16 PF08614.6 EDN08726.1 - 0.00047 20.0 0.7 0.00047 20.0 0.5 2.5 3 1 0 3 3 3 1 Autophagy protein 16 (ATG16) Cep57_MT_bd PF06657.8 EDN08726.1 - 0.15 12.0 2.3 0.42 10.6 0.1 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF722 PF05263.6 EDN08726.1 - 0.38 10.8 5.7 0.28 11.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF722) IncA PF04156.9 EDN08726.1 - 3.1 7.3 8.4 0.25 10.9 1.6 1.9 2 0 0 2 2 2 0 IncA protein WD40 PF00400.27 EDN08727.1 - 7.9e-06 25.5 10.4 0.0031 17.3 0.0 6.1 8 0 0 8 8 8 3 WD domain, G-beta repeat LisH PF08513.6 EDN08727.1 - 0.0025 17.5 0.2 0.0071 16.0 0.1 1.7 1 0 0 1 1 1 1 LisH DUF1751 PF08551.5 EDN08728.1 - 2.3e-27 95.2 3.9 4.1e-27 94.4 2.7 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EDN08728.1 - 0.0016 18.4 6.9 0.0025 17.8 4.8 1.3 1 0 0 1 1 1 1 Rhomboid family DUF3975 PF13126.1 EDN08728.1 - 0.12 12.4 3.2 0.23 11.6 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) MNHE PF01899.11 EDN08728.1 - 0.6 9.7 9.1 0.1 12.2 3.0 1.9 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit DUF4149 PF13664.1 EDN08728.1 - 1.2 9.2 7.5 0.18 11.8 1.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) L51_S25_CI-B8 PF05047.11 EDN08729.1 - 2.8e-15 55.7 0.0 4.4e-15 55.1 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF2458 PF10454.4 EDN08729.1 - 0.0056 16.5 1.6 0.0088 15.9 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) tRNA-synt_1 PF00133.17 EDN08730.1 - 5.6e-35 120.4 0.0 2e-24 85.5 0.0 3.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EDN08730.1 - 5.1e-17 61.6 0.2 5.1e-11 41.8 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EDN08730.1 - 1.4e-11 44.3 0.1 2.8e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EDN08730.1 - 4.3e-08 32.6 0.0 7.6e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EDN08730.1 - 0.049 12.2 0.0 0.14 10.8 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetases class I (K) Telomere_Sde2 PF13019.1 EDN08731.1 - 1.4e-11 44.3 4.1 2.8e-11 43.3 2.8 1.5 1 0 0 1 1 1 1 Telomere stability and silencing S10_plectin PF03501.10 EDN08732.1 - 9.1e-41 137.6 0.1 1.1e-40 137.3 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Peptidase_M20 PF01546.23 EDN08733.1 - 7.5e-05 22.3 0.0 7.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 AAA PF00004.24 EDN08734.1 - 6.1e-08 32.9 0.1 1.9e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 EDN08736.1 - 1.4e-18 66.9 0.0 3.2e-18 65.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN08736.1 - 4e-08 32.6 0.0 5.4e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDN08736.1 - 0.0061 15.6 0.3 0.085 11.9 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EDN08737.1 - 1.4e-38 132.5 0.0 1.2e-31 109.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN08737.1 - 2e-13 50.0 0.0 1.5e-11 43.8 0.0 2.1 1 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EDN08737.1 - 0.00011 21.2 0.0 0.0073 15.3 0.0 2.5 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDN08737.1 - 0.0034 16.3 0.0 0.0093 14.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EDN08737.1 - 0.02 13.7 0.1 2.8 6.6 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EDN08737.1 - 0.022 14.5 0.0 6 6.5 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN08737.1 - 0.029 13.9 0.0 0.058 12.9 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase WD40 PF00400.27 EDN08737.1 - 0.13 12.2 0.2 0.33 10.9 0.1 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat CRAL_TRIO PF00650.15 EDN08740.1 - 4.9e-29 100.8 0.1 4.2e-28 97.8 0.1 2.2 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDN08740.1 - 2.7e-16 59.4 0.2 9.9e-16 57.6 0.2 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EDN08740.1 - 1.3e-06 28.3 0.0 5.2e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Kringle PF00051.13 EDN08740.1 - 0.098 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Kringle domain DASH_Dam1 PF08653.5 EDN08741.1 - 1.2e-30 104.9 2.1 1.7e-30 104.5 1.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 UCH PF00443.24 EDN08743.1 - 3.9e-37 127.8 1.6 1.5e-34 119.3 1.1 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDN08743.1 - 1.9e-13 50.5 5.3 1.6e-09 37.6 0.1 2.9 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EDN08743.1 - 6.6e-07 29.3 0.4 6.6e-07 29.3 0.3 3.2 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Ytp1 PF10355.4 EDN08744.1 - 8.1e-115 382.6 8.2 8.1e-115 382.6 5.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EDN08744.1 - 2.2e-20 72.1 12.3 9.9e-11 41.1 0.7 3.8 2 1 1 3 3 3 3 Domain of unknown function (DUF2427) OTT_1508_deam PF14441.1 EDN08745.1 - 4e-10 39.6 0.1 7.1e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase PMC2NT PF08066.7 EDN08745.1 - 0.069 13.4 0.0 16 5.8 0.0 2.4 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Rhomboid PF01694.17 EDN08746.1 - 0.001 19.0 1.8 0.0013 18.8 1.2 1.2 1 0 0 1 1 1 1 Rhomboid family Gaa1 PF04114.9 EDN08747.1 - 1.2e-98 331.0 4.4 1.5e-98 330.6 3.0 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.22 EDN08748.1 - 2.8e-10 40.4 0.0 5.3e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 PCI domain DUF3990 PF13151.1 EDN08748.1 - 0.019 14.3 0.3 0.98 8.7 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3990) NAD_binding_10 PF13460.1 EDN08749.1 - 7.1e-18 65.2 0.0 9.6e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDN08749.1 - 4.6e-14 52.4 0.0 7.1e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EDN08749.1 - 1.5e-13 50.5 0.0 1.9e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EDN08749.1 - 3.2e-11 42.4 0.0 6.8e-11 41.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EDN08749.1 - 6.2e-08 31.8 0.0 1.2e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EDN08749.1 - 2.6e-05 23.2 0.1 0.0046 15.9 0.1 2.9 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 EDN08749.1 - 2.6e-05 24.1 0.0 0.0094 15.8 0.0 2.6 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 EDN08749.1 - 0.0041 16.8 0.0 2.2 7.9 0.0 2.4 2 0 0 2 2 2 2 KR domain Saccharop_dh PF03435.13 EDN08749.1 - 0.0077 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_synthase PF02540.12 EDN08749.1 - 0.0078 15.1 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 NAD synthase HIM1 PF08732.5 EDN08749.1 - 0.01 14.3 0.0 0.015 13.8 0.0 1.2 1 0 0 1 1 1 0 HIM1 DDE_Tnp_1_3 PF13612.1 EDN08749.1 - 0.03 14.0 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain HEM4 PF02602.10 EDN08750.1 - 3.7e-21 75.4 0.0 5.5e-20 71.6 0.0 1.9 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pkinase PF00069.20 EDN08751.1 - 2.6e-73 246.3 0.0 3.1e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN08751.1 - 3.7e-32 111.4 0.0 4.9e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN08751.1 - 0.00073 18.5 0.0 0.0015 17.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDN08751.1 - 0.0027 16.8 0.1 0.0044 16.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN08751.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDN08751.1 - 0.057 12.2 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sec23_trunk PF04811.10 EDN08753.1 - 1.5e-70 237.3 0.0 2.7e-70 236.5 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EDN08753.1 - 2.4e-23 81.5 0.0 2.4e-22 78.2 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EDN08753.1 - 1.2e-17 63.1 5.0 2e-17 62.4 3.5 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EDN08753.1 - 2.3e-17 63.3 0.0 4.6e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EDN08753.1 - 3.6e-08 32.9 0.0 9.5e-08 31.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Hemerythrin PF01814.18 EDN08754.1 - 4.7e-15 55.9 2.7 6.5e-15 55.4 1.8 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain CTK3_C PF12350.3 EDN08754.1 - 0.019 15.0 3.8 0.019 15.0 2.7 1.9 2 1 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus Peptidase_S46 PF10459.4 EDN08754.1 - 0.052 11.9 1.0 0.062 11.7 0.7 1.0 1 0 0 1 1 1 0 Peptidase S46 UPF0242 PF06785.6 EDN08754.1 - 0.48 9.0 3.5 0.87 8.1 1.4 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) adh_short PF00106.20 EDN08755.1 - 0.037 13.9 0.1 0.053 13.4 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Exotox-A_bind PF09101.5 EDN08755.1 - 0.053 12.6 0.0 0.11 11.5 0.0 1.5 2 0 0 2 2 2 0 Exotoxin A binding Kinesin PF00225.18 EDN08756.1 - 2.9e-82 276.0 0.0 6.1e-82 275.0 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain HHH PF00633.18 EDN08756.1 - 3.5e-07 29.5 1.2 0.0098 15.5 0.0 3.4 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.1 EDN08756.1 - 0.0011 19.1 0.0 0.0048 17.0 0.0 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_3 PF12836.2 EDN08756.1 - 0.0051 16.7 0.1 2.2 8.3 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif MFS_1 PF07690.11 EDN08757.1 - 6.3e-30 104.0 50.7 2.3e-18 66.0 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AIM24 PF01987.12 EDN08759.1 - 7.3e-05 22.3 0.0 0.00036 20.0 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial biogenesis AIM24 ABC_membrane PF00664.18 EDN08760.1 - 1.3e-36 126.4 9.1 1.8e-36 125.9 6.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EDN08760.1 - 1.7e-33 115.7 0.0 3.4e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EDN08760.1 - 1.8e-07 31.3 0.1 0.0047 16.9 0.0 2.4 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EDN08760.1 - 1e-05 24.8 0.1 0.0063 15.7 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EDN08760.1 - 7.7e-05 22.7 0.0 0.00032 20.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EDN08760.1 - 0.0001 23.0 0.0 0.00021 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDN08760.1 - 0.00099 19.2 0.0 0.006 16.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EDN08760.1 - 0.0042 16.5 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EDN08760.1 - 0.0044 16.4 0.0 0.011 15.2 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EDN08760.1 - 0.0047 16.3 0.1 0.0098 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDN08760.1 - 0.0081 16.0 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDN08760.1 - 0.0085 16.3 0.0 0.042 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 EDN08760.1 - 0.012 14.2 0.0 0.13 10.8 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.1 EDN08760.1 - 0.021 15.1 0.0 0.062 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EDN08760.1 - 0.021 14.0 0.0 0.042 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 EDN08760.1 - 0.024 14.5 0.1 0.22 11.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EDN08760.1 - 0.044 13.2 0.0 0.079 12.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 EDN08760.1 - 0.055 13.3 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EDN08760.1 - 0.076 13.2 0.0 0.57 10.3 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EDN08760.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2847 PF11009.3 EDN08760.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) SCHIP-1 PF10148.4 EDN08761.1 - 0.12 11.7 0.1 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Vac14_Fig4_bd PF11916.3 EDN08762.1 - 5.6e-56 188.5 10.2 1.6e-29 102.3 1.1 2.9 2 1 1 3 3 3 2 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EDN08762.1 - 4.2e-45 152.0 0.0 1.2e-42 144.2 0.0 3.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EDN08762.1 - 1.4e-10 40.3 1.6 0.00036 20.3 0.0 6.8 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 EDN08762.1 - 1.1e-08 35.2 2.3 0.0057 17.1 0.0 5.5 4 1 1 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.1 EDN08762.1 - 3.5e-08 33.5 0.3 0.0078 16.4 0.0 5.1 5 2 1 6 6 6 2 HEAT repeats Arm PF00514.18 EDN08762.1 - 0.0095 15.7 0.0 11 6.0 0.0 4.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EDN08762.1 - 0.011 15.1 0.1 7.1 5.9 0.0 4.2 4 2 1 5 5 5 0 CLASP N terminal SNF2_N PF00176.18 EDN08763.1 - 4.4e-63 212.8 0.0 6.2e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EDN08763.1 - 6.4e-24 84.8 0.3 1.3e-23 83.8 0.2 1.5 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EDN08763.1 - 5.3e-12 45.4 0.0 1.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EDN08763.1 - 0.0022 16.8 0.0 0.014 14.2 0.0 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 EDN08763.1 - 0.097 12.8 0.0 1.1 9.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain Mito_carr PF00153.22 EDN08764.1 - 2.7e-49 164.8 5.7 1.7e-19 69.2 0.1 3.3 2 2 1 3 3 3 3 Mitochondrial carrier protein zf-C2H2_jaz PF12171.3 EDN08765.1 - 2.4e-09 37.0 2.0 2.4e-09 37.0 1.4 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 EDN08765.1 - 0.006 16.1 0.3 0.013 15.0 0.2 1.5 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.2 EDN08765.1 - 0.017 15.1 1.0 0.033 14.3 0.7 1.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Ribosomal_L2 PF00181.18 EDN08765.1 - 0.05 13.5 2.1 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain Tna_leader PF08053.6 EDN08765.1 - 0.098 12.0 0.1 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophanese operon leader peptide zf-met PF12874.2 EDN08765.1 - 1.3 9.3 3.8 0.38 11.0 0.7 1.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Aconitase PF00330.15 EDN08767.1 - 6.2e-161 535.9 0.0 1.2e-159 531.7 0.0 2.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EDN08767.1 - 9.7e-47 158.3 0.0 1.7e-46 157.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Lactamase_B PF00753.22 EDN08768.1 - 1.8e-26 93.0 1.8 3.1e-26 92.2 1.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EDN08768.1 - 5.7e-06 25.9 0.0 7.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EDN08768.1 - 0.012 15.3 0.2 0.018 14.7 0.1 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Glyco_transf_20 PF00982.16 EDN08769.1 - 1.7e-200 666.5 0.0 1.9e-200 666.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EDN08769.1 - 0.007 15.8 0.2 0.034 13.6 0.0 2.0 2 0 0 2 2 2 1 Starch synthase catalytic domain Ribosomal_S17 PF00366.15 EDN08770.1 - 0.00026 20.9 0.4 0.00044 20.2 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 CAP_N PF01213.14 EDN08770.1 - 0.22 10.7 2.2 0.31 10.3 1.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA PF00004.24 EDN08771.1 - 3.2e-37 127.6 0.0 7.4e-37 126.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EDN08771.1 - 4.2e-08 32.9 0.0 3.1e-05 23.7 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EDN08771.1 - 4.6e-06 26.8 0.1 6.8e-05 23.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EDN08771.1 - 4.3e-05 23.5 0.0 8.9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EDN08771.1 - 0.00015 20.8 0.0 0.00026 20.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EDN08771.1 - 0.0012 18.6 0.1 0.0049 16.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 EDN08771.1 - 0.0044 16.6 0.0 0.0097 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EDN08771.1 - 0.0046 16.1 0.0 0.009 15.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EDN08771.1 - 0.0053 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EDN08771.1 - 0.0054 16.1 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EDN08771.1 - 0.0063 16.2 0.3 0.09 12.5 0.0 2.7 3 0 0 3 3 2 1 Part of AAA domain AAA_16 PF13191.1 EDN08771.1 - 0.0097 15.9 1.7 0.035 14.1 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EDN08771.1 - 0.013 14.2 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 EDN08771.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDN08771.1 - 0.017 14.5 0.1 0.13 11.6 0.0 2.3 1 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EDN08771.1 - 0.026 14.1 0.1 0.21 11.2 0.0 2.4 2 1 1 3 3 3 0 NACHT domain AAA_14 PF13173.1 EDN08771.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EDN08771.1 - 0.06 13.3 0.1 0.21 11.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.1 EDN08771.1 - 0.12 13.2 0.0 0.32 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EDN08771.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 EDN08771.1 - 0.24 10.5 0.0 0.51 9.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Mito_carr PF00153.22 EDN08772.1 - 1.8e-63 210.2 3.5 5e-22 77.4 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein 3Beta_HSD PF01073.14 EDN08773.1 - 5.6e-59 199.1 0.0 8.6e-59 198.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDN08773.1 - 1.8e-27 96.2 0.1 2.6e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EDN08773.1 - 7.1e-13 48.0 1.0 4.1e-11 42.2 0.1 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EDN08773.1 - 8.1e-10 38.0 0.1 1.1e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EDN08773.1 - 3.5e-09 36.9 0.0 5.5e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EDN08773.1 - 1.9e-06 27.9 0.4 1.3e-05 25.2 0.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EDN08773.1 - 3.8e-06 26.0 1.0 3.9e-05 22.7 0.4 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EDN08773.1 - 0.00016 21.4 0.8 0.0067 16.1 0.5 2.3 1 1 0 1 1 1 1 KR domain IBR PF01485.16 EDN08774.1 - 2.2e-21 75.4 46.9 3.4e-11 42.8 4.2 4.5 3 1 1 4 4 4 3 IBR domain Mog1 PF04603.7 EDN08774.1 - 8.1e-14 51.7 0.2 9e-13 48.3 0.0 2.5 2 0 0 2 2 2 1 Ran-interacting Mog1 protein zf-C3HC4_2 PF13923.1 EDN08774.1 - 2.7e-05 24.0 8.2 2.7e-05 24.0 5.7 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN08774.1 - 2.9e-05 23.7 44.7 0.00038 20.2 5.5 3.6 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EDN08774.1 - 6.6e-05 22.4 40.6 0.00057 19.4 3.6 4.4 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.3 EDN08774.1 - 0.0016 18.6 0.1 0.0071 16.6 0.0 2.0 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 zf-RING_5 PF14634.1 EDN08774.1 - 0.0098 15.6 9.5 0.0098 15.6 6.6 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EDN08774.1 - 0.3 11.0 28.6 0.049 13.5 0.5 4.3 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING NYN PF01936.13 EDN08775.1 - 0.00078 19.7 0.0 0.0033 17.7 0.0 1.7 1 1 0 2 2 2 1 NYN domain HSP9_HSP12 PF04119.7 EDN08776.1 - 1.9e-30 104.7 6.2 1.9e-30 104.7 4.3 2.1 2 0 0 2 2 2 1 Heat shock protein 9/12 YtxH PF12732.2 EDN08776.1 - 0.045 14.1 4.5 0.16 12.3 3.1 1.9 1 1 0 1 1 1 0 YtxH-like protein ISG65-75 PF11727.3 EDN08776.1 - 0.082 11.9 2.1 0.088 11.8 1.5 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF3484 PF11983.3 EDN08776.1 - 0.45 11.3 4.6 5.6 7.8 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3484) AAA_13 PF13166.1 EDN08777.1 - 0.0069 14.9 0.5 0.0092 14.5 0.4 1.1 1 0 0 1 1 1 1 AAA domain Nsp1_C PF05064.8 EDN08777.1 - 0.02 14.5 1.4 0.11 12.1 0.1 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region TarH PF02203.10 EDN08777.1 - 0.15 11.8 1.2 2 8.2 0.3 2.3 2 0 0 2 2 2 0 Tar ligand binding domain homologue ATG16 PF08614.6 EDN08777.1 - 0.95 9.2 8.0 0.17 11.7 2.5 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 EDN08777.1 - 2.6 7.0 10.2 0.12 11.3 1.8 2.3 1 1 2 3 3 3 0 Autophagy protein Apg6 COG6 PF06419.6 EDN08778.1 - 1.9e-210 700.1 0.0 2.3e-210 699.8 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 NIF3 PF01784.13 EDN08779.1 - 9.3e-51 172.7 0.0 1.2e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.13 EDN08780.1 - 4.3e-22 77.8 0.0 5.2e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Redoxin PF08534.5 EDN08781.1 - 4.6e-27 94.3 0.0 5.9e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin HSF_DNA-bind PF00447.12 EDN08783.1 - 1.1e-34 118.7 0.4 1.1e-34 118.7 0.3 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding DUF972 PF06156.8 EDN08783.1 - 0.033 14.5 1.5 0.033 14.5 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) CENP-Q PF13094.1 EDN08783.1 - 0.12 12.3 11.5 0.061 13.3 5.7 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit bZIP_1 PF00170.16 EDN08783.1 - 0.62 10.0 2.8 0.45 10.5 0.4 2.0 2 0 0 2 2 2 0 bZIP transcription factor FAST_2 PF08368.7 EDN08783.1 - 1.8 9.0 5.4 11 6.4 0.0 2.9 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 2 IncA PF04156.9 EDN08783.1 - 8.6 5.9 11.3 35 3.9 7.9 1.8 1 1 0 1 1 1 0 IncA protein Hexapep PF00132.19 EDN08784.1 - 4.1e-10 38.6 14.7 8.1e-05 21.9 1.0 4.3 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) W2 PF02020.13 EDN08784.1 - 4.3e-09 36.2 0.5 4.3e-09 36.2 0.3 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep_2 PF14602.1 EDN08784.1 - 0.0005 19.5 15.1 0.0006 19.3 0.4 4.1 4 1 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase SprT-like PF10263.4 EDN08785.1 - 4.6e-60 201.8 0.4 4.6e-60 201.8 0.3 1.6 2 0 0 2 2 2 1 SprT-like family Peptidase_MA_2 PF13485.1 EDN08785.1 - 0.062 13.3 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily DUF4379 PF14311.1 EDN08785.1 - 0.37 10.6 4.6 1.5 8.6 3.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) Glyco_hydro_72 PF03198.9 EDN08786.1 - 3.2e-131 437.0 6.8 4e-131 436.6 4.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EDN08786.1 - 3.3e-26 91.5 1.3 1.2e-25 89.7 0.9 2.1 1 0 0 1 1 1 1 X8 domain Glucan_synthase PF02364.10 EDN08790.1 - 0 1467.8 0.0 0 1467.3 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EDN08790.1 - 4.9e-40 136.1 1.1 1.3e-39 134.7 0.8 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.16 EDN08791.1 - 2.3e-30 105.8 0.0 2.7e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EDN08791.1 - 0.15 10.3 0.0 0.3 9.3 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_17 PF00332.13 EDN08792.1 - 4.2e-06 26.0 0.2 1.2e-05 24.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Pax2_C PF12403.3 EDN08792.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Paired-box protein 2 C terminal p450 PF00067.17 EDN08793.1 - 6.2e-11 41.4 0.0 5.9e-05 21.7 0.1 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF2013 PF09431.5 EDN08794.1 - 9.5e-53 177.7 1.1 9.5e-53 177.7 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Glyco_hydro_47 PF01532.15 EDN08795.1 - 1.8e-185 616.9 0.0 2.1e-185 616.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 APG9 PF04109.11 EDN08796.1 - 8.9e-170 564.5 2.4 1.2e-169 564.1 1.7 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 RasGAP PF00616.14 EDN08797.1 - 1e-45 155.8 0.0 1.9e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EDN08797.1 - 0.0027 17.4 0.0 0.0069 16.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain Tropomyosin PF00261.15 EDN08797.1 - 0.12 11.4 0.3 0.26 10.3 0.2 1.4 1 0 0 1 1 1 0 Tropomyosin DUF1803 PF08820.5 EDN08799.1 - 0.016 14.8 0.2 0.035 13.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) WD40 PF00400.27 EDN08801.1 - 4.4e-15 54.8 1.3 0.0044 16.8 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat COQ9 PF08511.6 EDN08803.1 - 2.5e-23 81.3 0.2 4.3e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 COQ9 AA_permease_2 PF13520.1 EDN08804.1 - 1.8e-25 89.3 11.2 1.8e-25 89.3 7.8 2.0 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 EDN08804.1 - 3.2e-20 71.9 11.8 3.2e-20 71.9 8.2 2.0 2 0 0 2 2 2 1 Amino acid permease DUF3918 PF13056.1 EDN08804.1 - 0.33 10.2 2.5 0.8 9.0 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) FmdA_AmdA PF03069.10 EDN08805.1 - 1.8e-53 181.5 0.0 1.6e-28 99.4 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family RRM_1 PF00076.17 EDN08807.1 - 1.7e-36 123.7 0.0 1.2e-16 60.0 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN08807.1 - 4.8e-30 103.3 0.0 5.3e-13 48.7 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN08807.1 - 9.3e-14 51.0 0.0 7e-07 28.9 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EDN08807.1 - 0.0039 16.9 0.3 2.6 7.8 0.0 3.3 3 1 0 3 3 3 2 Limkain b1 THRAP3_BCLAF1 PF15440.1 EDN08807.1 - 0.034 12.8 22.3 0.045 12.4 15.5 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family ATP-grasp_2 PF08442.5 EDN08807.1 - 0.071 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain GRP PF07172.6 EDN08807.1 - 6.5 7.3 51.0 4 7.9 22.8 3.6 3 0 0 3 3 3 0 Glycine rich protein family TrkH PF02386.11 EDN08808.1 - 1.1e-88 297.1 8.5 6.5e-57 192.6 5.0 2.2 1 1 1 2 2 2 2 Cation transport protein PH PF00169.24 EDN08809.1 - 1.4e-11 44.5 0.1 3.3e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 EDN08809.1 - 0.25 8.8 0.1 0.37 8.2 0.1 1.2 1 0 0 1 1 1 0 Prominin Tim17 PF02466.14 EDN08810.1 - 4.7e-15 55.7 5.8 6.7e-15 55.2 4.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family RPT PF13446.1 EDN08811.1 - 1.8e-51 171.3 0.2 2.4e-21 74.8 0.4 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.24 EDN08811.1 - 1.4e-46 158.7 0.0 3.3e-46 157.5 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDN08811.1 - 6.4e-10 38.9 0.2 3.6e-06 26.6 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CoA_trans PF01144.18 EDN08812.1 - 1.9e-60 203.7 2.6 2e-32 112.1 0.3 4.0 3 1 0 3 3 3 3 Coenzyme A transferase DUF2370 PF10176.4 EDN08813.1 - 1.6e-88 296.0 0.0 2.8e-88 295.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 EDN08813.1 - 0.067 13.4 0.1 0.3 11.3 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) WSC PF01822.14 EDN08814.1 - 2.2e-13 49.9 8.1 2.2e-13 49.9 5.6 1.7 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 EDN08814.1 - 1.3e-05 24.4 2.1 1.5e-05 24.2 0.2 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4366 PF14283.1 EDN08814.1 - 0.013 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CDP-OH_P_transf PF01066.16 EDN08815.1 - 6.7e-11 42.3 2.8 6.7e-11 42.3 1.9 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Gar1 PF04410.9 EDN08816.1 - 1.6e-18 66.6 1.4 2.9e-18 65.7 0.0 1.9 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.20 EDN08817.1 - 1.6e-27 96.1 0.0 6.9e-27 94.1 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDN08817.1 - 7.3e-15 54.6 0.1 1.4e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EDN08817.1 - 5.6e-12 45.3 0.0 1.1e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EDN08817.1 - 0.00053 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain Fungal_trans PF04082.13 EDN08818.1 - 5.4e-26 91.0 0.0 1.3e-25 89.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN08818.1 - 7.3e-10 38.5 13.1 1.2e-09 37.8 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M41 PF01434.13 EDN08819.1 - 4.4e-75 251.8 0.0 6.6e-75 251.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EDN08819.1 - 3.7e-42 143.6 0.0 7.9e-42 142.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EDN08819.1 - 1.5e-08 34.7 0.1 3.8e-08 33.4 0.1 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 EDN08819.1 - 0.00016 21.4 0.1 0.0052 16.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN08819.1 - 0.0003 20.9 0.6 0.23 11.5 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EDN08819.1 - 0.0028 18.4 0.0 0.011 16.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN08819.1 - 0.0036 17.0 0.3 0.02 14.6 0.4 2.1 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 EDN08819.1 - 0.0037 16.3 0.0 0.012 14.6 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EDN08819.1 - 0.0077 14.9 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EDN08819.1 - 0.013 15.4 0.2 0.15 12.0 0.1 2.4 1 1 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.12 EDN08819.1 - 0.022 14.1 0.0 0.055 12.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EDN08819.1 - 0.025 13.9 0.4 0.17 11.2 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_2 PF07724.9 EDN08819.1 - 0.033 14.0 0.0 0.14 12.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EDN08819.1 - 0.1 12.4 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF1295 PF06966.7 EDN08820.1 - 0.085 12.1 2.9 2.9 7.1 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1295) Topoisom_bac PF01131.15 EDN08821.1 - 2.4e-86 290.0 0.0 2.9e-86 289.8 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EDN08821.1 - 1.8e-18 66.3 0.0 4.1e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Toprim domain AAA_13 PF13166.1 EDN08822.1 - 4.8e-05 22.0 45.1 0.027 12.9 14.0 3.2 1 1 2 3 3 3 3 AAA domain DUF869 PF05911.6 EDN08822.1 - 4.8e-05 21.8 50.5 0.0072 14.6 15.2 3.4 1 1 2 3 3 3 3 Plant protein of unknown function (DUF869) IncA PF04156.9 EDN08822.1 - 0.00029 20.5 51.7 0.018 14.6 7.9 5.2 2 1 2 4 4 4 3 IncA protein Spc7 PF08317.6 EDN08822.1 - 0.00059 18.5 51.9 0.0069 15.0 1.8 4.3 2 1 2 4 4 4 3 Spc7 kinetochore protein MscS_porin PF12795.2 EDN08822.1 - 0.0031 16.8 2.1 0.0031 16.8 1.4 5.5 4 1 1 5 5 5 3 Mechanosensitive ion channel porin domain APG6 PF04111.7 EDN08822.1 - 0.0066 15.5 8.0 0.0066 15.5 5.5 4.4 3 1 1 4 4 4 1 Autophagy protein Apg6 ATG16 PF08614.6 EDN08822.1 - 0.0086 15.9 4.1 0.0086 15.9 2.8 6.7 3 1 4 8 8 8 1 Autophagy protein 16 (ATG16) GAS PF13851.1 EDN08822.1 - 0.38 9.9 55.0 0.015 14.4 10.6 4.6 2 2 1 4 4 4 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 EDN08822.1 - 1.1 8.8 49.8 0.82 9.3 2.4 5.8 2 2 4 6 6 6 0 Mnd1 family SlyX PF04102.7 EDN08822.1 - 1.8 8.9 0.0 1.7 9.1 1.0 7.5 7 1 0 7 7 7 0 SlyX DUF1515 PF07439.6 EDN08822.1 - 2 8.2 18.7 2.4 8.0 0.1 5.1 2 1 1 4 4 4 0 Protein of unknown function (DUF1515) PilJ PF13675.1 EDN08822.1 - 2.8 8.2 21.1 5.5 7.3 0.1 6.0 3 3 3 6 6 6 0 Type IV pili methyl-accepting chemotaxis transducer N-term EzrA PF06160.7 EDN08823.1 - 0.0048 15.1 2.4 0.054 11.6 1.5 2.1 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA 7TMR-HDED PF07697.6 EDN08823.1 - 0.043 13.5 0.2 0.12 12.0 0.1 1.8 1 1 0 1 1 1 0 7TM-HD extracellular Apolipoprotein PF01442.13 EDN08823.1 - 0.056 12.9 2.3 0.14 11.6 1.6 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 EDN08823.1 - 0.12 12.1 3.1 15 5.3 1.7 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CALCOCO1 PF07888.6 EDN08823.1 - 0.13 10.4 2.5 0.13 10.5 0.4 1.7 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cep57_CLD_2 PF14197.1 EDN08823.1 - 0.25 11.3 2.6 0.41 10.6 0.6 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF4149 PF13664.1 EDN08824.1 - 8.1e-25 86.8 1.5 1.7e-24 85.8 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ku PF02735.11 EDN08825.1 - 4.7e-28 97.9 0.0 7.5e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 EDN08825.1 - 6.9e-15 54.9 0.0 1.5e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.10 EDN08825.1 - 7.7e-10 38.5 0.0 1.1e-08 34.7 0.0 2.6 2 1 1 3 3 3 1 Ku70/Ku80 N-terminal alpha/beta domain PX PF00787.19 EDN08826.1 - 2.6e-14 52.9 0.0 1.2e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 EDN08826.1 - 1.8e-05 24.2 5.0 4.7e-05 22.9 3.4 1.8 1 0 0 1 1 1 1 SNARE domain HXXSHH PF07586.6 EDN08826.1 - 0.98 8.2 4.9 2.6 6.8 0.6 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1552) DUF676 PF05057.9 EDN08827.1 - 4.1e-05 22.9 0.0 7.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) UPF0227 PF05728.7 EDN08827.1 - 0.00013 21.7 0.0 0.00031 20.5 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.20 EDN08827.1 - 0.00015 21.4 0.0 0.00039 20.0 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EDN08827.1 - 0.00027 20.8 0.0 0.00051 20.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN08827.1 - 0.00032 20.4 0.0 0.00048 19.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EDN08827.1 - 0.00087 18.9 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 EDN08827.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 EDN08827.1 - 0.029 14.6 0.3 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain DUF2974 PF11187.3 EDN08827.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SIP1 PF04938.7 EDN08828.1 - 0.08 12.2 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) tRNA-synt_2 PF00152.15 EDN08829.1 - 3.8e-73 246.1 0.1 5e-73 245.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Hydrolase_like PF13242.1 EDN08829.1 - 4.3e-08 32.7 0.0 1.1e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like tRNA_anti-codon PF01336.20 EDN08829.1 - 6.1e-05 22.7 0.4 0.00011 21.9 0.3 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EDN08829.1 - 0.12 11.5 0.2 4.6 6.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) F-box-like PF12937.2 EDN08830.1 - 4.4e-10 39.1 1.8 4.4e-10 39.1 1.3 1.9 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EDN08830.1 - 0.021 14.5 7.0 0.69 9.7 0.0 3.9 3 1 1 4 4 4 0 Leucine rich repeat F-box PF00646.28 EDN08830.1 - 0.049 13.3 1.2 0.17 11.5 0.2 2.5 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.2 EDN08830.1 - 0.49 10.0 10.1 23 4.7 0.1 5.0 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) Adaptin_N PF01602.15 EDN08831.1 - 1.7e-92 310.4 0.0 8.6e-53 179.4 0.3 2.1 1 1 1 2 2 2 2 Adaptin N terminal region COP-gamma_platf PF08752.5 EDN08831.1 - 1.5e-60 203.4 1.2 3.2e-60 202.3 0.8 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EDN08831.1 - 3e-13 49.8 5.8 5.1e-05 23.4 0.1 5.9 2 2 3 5 5 5 3 HEAT repeats HEAT_PBS PF03130.11 EDN08831.1 - 0.001 19.3 3.8 6.9 7.4 0.1 4.5 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat DUF3730 PF12530.3 EDN08831.1 - 0.0018 18.2 0.4 0.0083 16.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3730) HEAT PF02985.17 EDN08831.1 - 0.0018 18.1 7.3 0.55 10.4 0.2 5.7 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EDN08831.1 - 1.4 9.5 8.9 0.34 11.4 0.8 3.8 4 1 0 4 4 4 0 HEAT-like repeat Phosducin PF02114.11 EDN08832.1 - 0.0015 17.3 0.0 0.0015 17.3 0.0 1.0 1 0 0 1 1 1 1 Phosducin bZIP_1 PF00170.16 EDN08833.1 - 1.7e-06 27.9 13.7 3.3e-06 26.9 9.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor EndoU_bacteria PF14436.1 EDN08833.1 - 0.0074 16.1 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 Bacterial EndoU nuclease GAS PF13851.1 EDN08833.1 - 0.012 14.8 6.3 0.017 14.2 4.4 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 EDN08833.1 - 0.019 14.6 5.1 0.033 13.9 3.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.6 EDN08833.1 - 0.024 14.5 1.3 0.044 13.6 0.9 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Glutaredoxin2_C PF04399.8 EDN08833.1 - 0.034 13.7 1.4 0.068 12.7 1.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain bZIP_Maf PF03131.12 EDN08833.1 - 0.066 13.5 12.1 0.11 12.8 8.4 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor V_ATPase_I PF01496.14 EDN08833.1 - 0.15 9.8 0.9 0.19 9.5 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CALCOCO1 PF07888.6 EDN08833.1 - 0.54 8.4 9.8 0.032 12.5 3.1 1.6 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like bZIP_2 PF07716.10 EDN08833.1 - 0.89 9.4 18.6 9.2 6.1 12.9 2.1 1 1 0 1 1 1 0 Basic region leucine zipper Jnk-SapK_ap_N PF09744.4 EDN08833.1 - 0.97 9.4 7.6 1.5 8.7 5.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HALZ PF02183.13 EDN08833.1 - 1.1 8.9 7.2 0.18 11.5 1.7 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Bap31 PF05529.7 EDN08833.1 - 1.6 8.1 4.4 2.4 7.5 3.1 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Pox_A_type_inc PF04508.7 EDN08833.1 - 4.6 7.2 7.6 0.72 9.7 2.1 2.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF3824 PF12868.2 EDN08833.1 - 5 8.0 10.7 0.18 12.7 1.1 2.3 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) DivIC PF04977.10 EDN08833.1 - 7.9 6.0 8.8 3.7 7.0 0.3 2.2 1 1 1 2 2 2 0 Septum formation initiator MFS_1 PF07690.11 EDN08834.1 - 0.0029 16.3 6.3 0.0035 16.1 4.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EDN08834.1 - 0.012 14.0 1.3 0.014 13.7 0.9 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein YesK PF14150.1 EDN08834.1 - 0.058 13.5 2.3 0.089 12.9 1.6 1.2 1 0 0 1 1 1 0 YesK-like protein DUF1304 PF06993.7 EDN08834.1 - 0.5 10.1 3.1 1.8 8.3 2.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1304) DUF308 PF03729.8 EDN08834.1 - 3 7.9 8.4 2.6 8.1 2.5 2.2 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) MFS_1 PF07690.11 EDN08835.1 - 5.7e-14 51.5 6.4 6.7e-14 51.3 4.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_47 PF01532.15 EDN08836.1 - 2.5e-166 553.8 0.0 2.9e-166 553.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 EDN08836.1 - 0.025 12.8 0.0 1.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) DUF3716 PF12511.3 EDN08837.1 - 2.6e-18 65.3 2.0 3.7e-18 64.8 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) GCR1_C PF12550.3 EDN08838.1 - 6.6e-16 57.9 0.3 3.3e-15 55.6 0.0 2.3 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Helitron_like_N PF14214.1 EDN08838.1 - 0.94 9.1 6.4 0.32 10.6 0.6 2.1 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus DUF3435 PF11917.3 EDN08839.1 - 3.3e-138 460.9 3.1 1.1e-76 258.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3435) Sec23_helical PF04815.10 EDN08840.1 - 0.023 14.1 0.0 0.03 13.7 0.0 1.3 1 1 0 1 1 1 0 Sec23/Sec24 helical domain Dynamin_N PF00350.18 EDN08842.1 - 2.4e-12 46.9 0.5 9.7e-07 28.7 0.0 3.0 2 1 1 3 3 3 2 Dynamin family Dynamin_M PF01031.15 EDN08842.1 - 1.7e-11 43.4 0.0 6.5e-10 38.2 0.0 2.2 1 1 0 1 1 1 1 Dynamin central region AAA_29 PF13555.1 EDN08842.1 - 0.0053 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EDN08842.1 - 0.0062 16.4 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.1 EDN08842.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EDN08842.1 - 0.041 14.3 0.0 0.23 11.9 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein DUF3723 PF12520.3 EDN08843.1 - 8.4e-168 559.0 0.0 8.4e-168 559.0 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3723) Pkinase PF00069.20 EDN08844.1 - 1.7e-08 33.9 0.0 3e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN08844.1 - 7.9e-07 28.3 0.0 1.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_8 PF08022.7 EDN08845.1 - 4.7e-10 39.2 0.0 7.6e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EDN08845.1 - 1.5e-08 34.6 0.0 2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EDN08845.1 - 0.063 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF3435 PF11917.3 EDN08847.1 - 9.6e-154 512.0 0.3 1.2e-153 511.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2_4 PF13894.1 EDN08847.1 - 0.88 10.0 7.6 5.4 7.5 0.8 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger Pkinase PF00069.20 EDN08848.1 - 9.4e-24 83.9 0.0 2.1e-23 82.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN08848.1 - 4e-07 29.3 0.0 2.6e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EDN08848.1 - 0.0042 16.1 0.0 0.0066 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN08848.1 - 0.007 16.1 0.0 0.19 11.4 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EDN08848.1 - 0.069 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.4 EDN08848.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF3543 PF12063.3 EDN08849.1 - 0.01 15.0 0.2 0.012 14.8 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) Fe_dep_repr_C PF02742.10 EDN08849.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain Exo_endo_phos_2 PF14529.1 EDN08850.1 - 3.4e-23 81.4 0.5 7.2e-23 80.4 0.1 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN08850.1 - 9.4e-09 35.5 0.5 1.5e-08 34.8 0.4 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EDN08851.1 - 3.4e-23 82.1 0.0 6.5e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN08851.1 - 3.1e-16 59.9 0.1 7e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 RNase H APH PF01636.18 EDN08854.1 - 2.9e-16 59.9 0.0 8.9e-16 58.3 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EDN08854.1 - 0.027 13.1 0.0 0.67 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DNA_pol_A_exo1 PF01612.15 EDN08855.1 - 4.4e-05 23.0 0.0 0.00016 21.2 0.0 1.8 1 1 1 2 2 2 1 3'-5' exonuclease Myb_DNA-binding PF00249.26 EDN08856.1 - 2e-10 40.5 1.3 6.5e-10 38.9 0.1 2.4 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN08856.1 - 1.1e-08 35.0 6.5 4.2e-08 33.1 0.0 2.2 1 1 1 2 2 2 1 Myb-like DNA-binding domain DUF3546 PF12066.3 EDN08856.1 - 0.2 11.6 2.6 0.33 10.9 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) S1-P1_nuclease PF02265.11 EDN08857.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease DUF3461 PF11944.3 EDN08857.1 - 0.01 15.6 2.0 0.018 14.8 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) SidE PF12252.3 EDN08857.1 - 0.17 9.1 2.5 0.23 8.7 1.7 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein Pkinase PF00069.20 EDN08862.1 - 4.5e-38 130.8 0.0 5.6e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN08862.1 - 4e-14 52.3 0.0 5.4e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN08862.1 - 1.1e-05 25.3 0.0 0.0015 18.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Hydantoinase_B PF02538.9 EDN08864.1 - 1.4e-194 647.2 0.0 1.7e-194 646.9 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EDN08864.1 - 1.9e-95 319.2 0.0 4.7e-95 318.0 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EDN08864.1 - 6.4e-55 185.3 0.2 3.2e-53 179.8 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Kelch_3 PF13415.1 EDN08866.1 - 3.1e-29 100.4 6.7 4.1e-07 29.9 0.1 5.0 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EDN08866.1 - 1.1e-28 98.6 1.2 2.6e-08 33.6 0.0 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.20 EDN08866.1 - 4e-28 96.6 0.0 1.4e-11 43.7 0.1 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 EDN08866.1 - 2e-27 94.6 6.4 3.1e-08 33.2 0.4 5.4 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EDN08866.1 - 1.8e-26 91.1 1.2 6.9e-11 41.8 0.3 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.10 EDN08866.1 - 1.6e-20 71.9 1.3 1.3e-08 34.2 0.1 5.6 5 0 0 5 5 5 4 Kelch motif Raptor_N PF14538.1 EDN08867.1 - 4.2e-64 215.0 0.0 7.3e-64 214.2 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EDN08867.1 - 0.00011 21.9 5.3 0.41 10.6 0.0 4.3 4 1 0 4 4 4 2 WD domain, G-beta repeat HEAT PF02985.17 EDN08867.1 - 0.0016 18.3 2.8 0.76 10.0 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat Peptidase_C14 PF00656.17 EDN08867.1 - 0.015 15.0 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Caspase domain BBS2_Mid PF14783.1 EDN08867.1 - 0.14 11.9 1.7 0.16 11.7 0.2 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.4 EDN08867.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain zf-RING_2 PF13639.1 EDN08869.1 - 5.1e-14 51.8 5.8 8e-14 51.1 4.0 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EDN08869.1 - 1.8e-11 43.6 0.0 4.5e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 EDN08869.1 - 1.5e-09 37.6 5.4 2.4e-09 37.0 3.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDN08869.1 - 5.8e-09 35.9 1.8 1.1e-08 35.0 1.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDN08869.1 - 1.7e-08 33.9 3.9 2.7e-08 33.3 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN08869.1 - 2.9e-08 33.2 3.2 4.3e-08 32.6 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN08869.1 - 1.3e-07 31.2 2.9 2e-07 30.6 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EDN08869.1 - 0.00061 19.5 0.5 0.0011 18.7 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EDN08869.1 - 0.02 14.6 3.2 0.047 13.4 2.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 EDN08869.1 - 0.041 13.8 2.3 0.1 12.5 1.6 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EDN08869.1 - 0.058 13.2 3.1 0.14 12.0 2.2 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EDN08869.1 - 0.079 13.0 4.4 0.14 12.1 3.1 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EDN08869.1 - 0.49 10.0 3.1 0.83 9.2 2.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EDN08869.1 - 1.3 8.7 3.0 2.3 7.9 2.1 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EDN08869.1 - 2 8.4 3.9 3.8 7.5 2.7 1.5 1 0 0 1 1 1 0 RING-like domain UPF0118 PF01594.11 EDN08870.1 - 0.074 12.0 1.1 3.5 6.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF20 LysM PF01476.15 EDN08871.1 - 0.026 14.4 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 LysM domain Chitin_bind_1 PF00187.14 EDN08871.1 - 0.14 12.2 49.2 0.083 12.8 9.0 3.9 3 0 0 3 3 3 0 Chitin recognition protein ARHGEF5_35 PF15441.1 EDN08871.1 - 3.8 6.1 5.1 5.4 5.6 3.5 1.2 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 Y_phosphatase3 PF13350.1 EDN08872.1 - 5.9e-40 137.2 0.0 8.1e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EDN08872.1 - 2.4e-05 24.3 0.0 8.4e-05 22.6 0.0 2.0 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EDN08872.1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EDN08872.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family FHA PF00498.21 EDN08873.1 - 5.6e-16 58.4 0.0 1.7e-15 56.8 0.0 1.9 2 0 0 2 2 2 1 FHA domain DUF2203 PF09969.4 EDN08873.1 - 0.46 10.7 10.2 1.2 9.4 0.7 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1515 PF07439.6 EDN08873.1 - 2.3 8.0 11.7 0.44 10.3 1.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Mnd1 PF03962.10 EDN08873.1 - 10 5.7 21.2 1.6 8.3 3.8 2.9 2 1 0 2 2 2 0 Mnd1 family Romo1 PF10247.4 EDN08874.1 - 2.7e-25 88.3 16.1 4e-25 87.7 11.2 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 TTKRSYEDQ PF10212.4 EDN08876.1 - 0.053 12.4 0.0 0.059 12.2 0.0 1.0 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein BBS1 PF14779.1 EDN08877.1 - 0.15 10.9 1.4 0.21 10.5 1.0 1.4 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 1 Alpha_GJ PF03229.8 EDN08877.1 - 1 9.6 14.5 1.1 9.6 10.1 1.0 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF3185 PF11381.3 EDN08877.1 - 7.5 6.4 7.8 5.3 6.8 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3185) Arb2 PF09757.4 EDN08878.1 - 1.1e-45 155.2 0.0 2e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Arb2 domain LRR_4 PF12799.2 EDN08879.1 - 1e-15 56.9 1.9 1.3e-10 40.6 0.2 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDN08879.1 - 4e-11 42.5 1.5 2.6e-10 39.8 0.4 2.2 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 EDN08879.1 - 2e-08 33.1 4.2 0.18 11.9 0.0 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 EDN08879.1 - 4.4e-06 26.0 2.7 0.18 12.1 0.0 4.1 3 0 0 3 3 3 2 Leucine rich repeat Rad50_zn_hook PF04423.9 EDN08879.1 - 0.00093 18.6 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Rad50 zinc hook motif Ribosomal_S14 PF00253.16 EDN08880.1 - 4.9e-17 61.0 1.9 5.6e-16 57.6 0.3 2.1 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e QLQ PF08880.6 EDN08880.1 - 0.047 13.1 0.8 0.24 10.8 0.1 2.2 2 0 0 2 2 2 0 QLQ Coatomer_b_Cpla PF14806.1 EDN08880.1 - 0.15 11.8 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Myc_N PF01056.13 EDN08881.1 - 0.042 13.0 4.8 0.055 12.6 3.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PBP1_TM PF14812.1 EDN08881.1 - 0.17 12.2 7.2 0.25 11.6 5.0 1.3 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 EDN08881.1 - 0.52 10.0 4.5 0.73 9.6 3.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal VID27 PF08553.5 EDN08881.1 - 0.59 8.2 3.1 0.65 8.1 2.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein NESP55 PF06390.7 EDN08881.1 - 0.85 8.9 15.0 0.33 10.2 1.1 2.1 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) CENP-B_dimeris PF09026.5 EDN08881.1 - 4.3 7.6 9.8 6.5 7.0 6.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ATP-synt_J PF04911.7 EDN08882.1 - 3.4e-27 93.6 1.4 3.8e-27 93.5 1.0 1.0 1 0 0 1 1 1 1 ATP synthase j chain DASH_Spc19 PF08287.6 EDN08883.1 - 6.9e-58 194.6 6.9 9.2e-58 194.2 4.8 1.2 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.7 EDN08883.1 - 0.026 14.5 0.5 0.078 13.0 0.2 1.7 1 1 1 2 2 2 0 Mur ligase middle domain Cut8_N PF14482.1 EDN08883.1 - 0.034 14.1 1.2 0.094 12.7 0.8 1.7 1 1 0 1 1 1 0 Cut8 proteasome-binding domain DUF4611 PF15387.1 EDN08883.1 - 0.53 10.4 3.7 0.6 10.2 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Rogdi_lz PF10259.4 EDN08884.1 - 1.9e-79 266.6 0.0 2.7e-79 266.0 0.0 1.2 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rsm22 PF09243.5 EDN08884.1 - 2e-28 99.1 0.0 2.8e-27 95.4 0.0 2.4 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 EDN08884.1 - 0.13 12.8 0.2 1.7 9.2 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain SUR7 PF06687.7 EDN08885.1 - 1.9e-38 132.1 5.8 2.2e-38 131.9 4.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family UPF0233 PF06781.7 EDN08885.1 - 0.0062 16.1 2.1 0.0062 16.1 1.5 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0233) DUF4491 PF14898.1 EDN08885.1 - 0.099 12.8 1.7 0.28 11.3 1.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Amastin PF07344.6 EDN08885.1 - 0.21 11.2 15.1 0.017 14.7 5.2 2.5 3 1 0 3 3 3 0 Amastin surface glycoprotein Clc-like PF07062.7 EDN08885.1 - 0.35 10.1 5.3 0.046 12.9 0.8 1.6 2 0 0 2 2 2 0 Clc-like Claudin_2 PF13903.1 EDN08885.1 - 2.7 7.6 19.0 0.24 11.0 8.9 2.3 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Ndc1_Nup PF09531.5 EDN08885.1 - 8.7 4.6 8.3 11 4.2 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HSP70 PF00012.15 EDN08886.1 - 2.1e-44 151.4 0.5 5.4e-41 140.2 0.1 2.5 1 1 0 2 2 2 2 Hsp70 protein GCIP PF13324.1 EDN08886.1 - 0.11 11.7 0.6 0.17 11.0 0.4 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nucleoplasmin PF03066.10 EDN08886.1 - 0.14 11.6 5.5 0.27 10.7 3.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 EDN08886.1 - 0.5 9.4 3.4 0.91 8.6 2.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Tom22 PF04281.8 EDN08886.1 - 0.74 9.3 3.9 1.4 8.4 2.7 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 PBP1_TM PF14812.1 EDN08886.1 - 0.9 9.8 5.9 1.8 8.9 4.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 EDN08886.1 - 5.8 5.5 10.4 11 4.6 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rpp20 PF12328.3 EDN08887.1 - 4.4e-51 172.3 13.5 1.2e-50 170.9 9.3 1.6 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EDN08887.1 - 1.6e-23 82.0 1.4 2.8e-23 81.2 1.0 1.4 1 0 0 1 1 1 1 Alba PhzC-PhzF PF02567.11 EDN08890.1 - 3.2e-12 46.2 0.1 3.8e-11 42.7 0.1 2.1 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein UDP-g_GGTase PF06427.6 EDN08893.1 - 1.1e-70 237.2 0.0 2.6e-70 235.9 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Acyl-CoA_dh_1 PF00441.19 EDN08893.1 - 1.3e-31 109.7 0.4 2.6e-31 108.7 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_transf_8 PF01501.15 EDN08893.1 - 0.00011 21.6 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Acyl-CoA_dh_2 PF08028.6 EDN08893.1 - 0.00018 21.7 0.0 0.00041 20.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Myb_DNA-binding PF00249.26 EDN08894.1 - 3.6e-15 55.7 0.5 3.2e-06 27.0 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN08894.1 - 7.7e-15 54.7 1.3 2.3e-10 40.4 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDN08894.1 - 0.0047 17.0 3.9 0.024 14.7 2.7 2.2 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EDN08894.1 - 0.15 12.2 0.3 0.15 12.2 0.2 2.6 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Amidohydro_1 PF01979.15 EDN08895.1 - 4.6e-22 79.1 0.0 2e-13 50.6 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EDN08895.1 - 1.5e-19 71.1 1.3 1.3e-15 58.1 1.0 2.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EDN08895.1 - 1.1e-08 34.8 0.1 2.5e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EDN08895.1 - 1.2e-05 24.7 0.1 0.025 13.8 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family DARPP-32 PF05395.7 EDN08895.1 - 0.14 12.3 3.9 0.24 11.5 2.7 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Daxx PF03344.10 EDN08895.1 - 0.17 10.3 7.9 0.25 9.7 5.5 1.2 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 EDN08895.1 - 0.34 9.5 11.3 0.48 9.0 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EDN08895.1 - 1.3 6.9 6.4 1.8 6.4 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Pex14_N PF04695.8 EDN08895.1 - 4.6 7.3 6.9 0.47 10.4 1.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Vma12 PF11712.3 EDN08896.1 - 7e-39 132.7 0.0 9.1e-39 132.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Prefoldin PF02996.12 EDN08897.1 - 1.7e-28 98.6 0.1 2.3e-28 98.2 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit MAD PF05557.8 EDN08897.1 - 0.014 13.5 0.1 0.026 12.6 0.1 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein Prefoldin_2 PF01920.15 EDN08897.1 - 0.099 12.4 0.3 0.53 10.0 0.0 2.1 2 1 0 2 2 2 0 Prefoldin subunit CENP-Q PF13094.1 EDN08897.1 - 0.23 11.4 2.1 0.25 11.3 0.3 1.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit PH PF00169.24 EDN08898.1 - 7.6e-13 48.5 0.5 2.2e-12 47.0 0.1 2.1 2 0 0 2 2 2 1 PH domain GRAM PF02893.15 EDN08898.1 - 7.8e-13 47.7 0.2 8.7e-05 21.9 0.0 3.4 3 0 0 3 3 3 3 GRAM domain PH_11 PF15413.1 EDN08898.1 - 4.4e-06 26.9 0.2 1.2e-05 25.4 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Glyco_transf_28 PF03033.15 EDN08898.1 - 1.3e-05 25.0 0.0 2.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH_3 PF14593.1 EDN08898.1 - 6e-05 22.8 0.1 0.00023 21.0 0.1 1.9 1 1 0 1 1 1 1 PH domain PH_8 PF15409.1 EDN08898.1 - 0.0026 17.7 0.4 0.0073 16.3 0.3 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 EDN08898.1 - 0.0092 14.5 0.1 0.023 13.2 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase DUF436 PF04260.7 EDN08898.1 - 0.24 10.8 0.1 2.2 7.7 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF436) Prenylcys_lyase PF07156.9 EDN08899.1 - 1.6e-41 142.4 0.0 3e-28 98.7 0.0 2.1 2 0 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 EDN08899.1 - 1.7e-11 43.9 0.1 7.9e-11 41.8 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EDN08899.1 - 1.7e-06 27.3 0.0 5.3e-05 22.4 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase DAO PF01266.19 EDN08899.1 - 0.00035 19.5 0.1 0.00058 18.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EDN08899.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDN08899.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN08899.1 - 0.083 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family MAP7 PF05672.6 EDN08901.1 - 0.034 13.5 1.5 0.05 12.9 1.0 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Flu_NS1 PF00600.14 EDN08901.1 - 0.041 13.0 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) PCI_Csn8 PF10075.4 EDN08903.1 - 8.3e-47 158.5 0.0 1.1e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EDN08903.1 - 8.5e-23 80.9 0.2 1.1e-22 80.6 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PDCD2_C PF04194.8 EDN08904.1 - 2.2e-40 137.9 0.0 7.7e-40 136.1 0.0 1.8 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain A2L_zn_ribbon PF08792.5 EDN08904.1 - 0.009 15.4 0.3 0.92 9.0 0.0 2.5 2 0 0 2 2 2 2 A2L zinc ribbon domain Ubiq-Cytc-red_N PF09165.5 EDN08904.1 - 0.67 10.3 5.6 0.11 12.7 1.0 1.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal Folliculin PF11704.3 EDN08905.1 - 2.7e-47 160.4 0.0 3.7e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport RNA_polI_A34 PF08208.6 EDN08908.1 - 2.5e-06 27.2 11.3 2.5e-06 27.2 7.8 2.1 1 1 1 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 SHMT PF00464.14 EDN08909.1 - 1.3e-138 461.7 0.1 1.7e-137 458.0 0.0 1.9 1 1 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EDN08909.1 - 0.0023 17.1 0.0 0.0037 16.4 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EDN08909.1 - 0.0091 14.9 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3040 PF11239.3 EDN08909.1 - 0.057 13.4 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Metalloenzyme PF01676.13 EDN08910.1 - 3.9e-76 255.7 0.1 4.4e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EDN08910.1 - 2.2e-67 226.6 0.2 3.2e-66 222.8 0.2 2.1 1 1 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EDN08910.1 - 5.2e-07 29.3 0.0 7.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EDN08910.1 - 2.5e-06 26.9 0.0 2.1e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.15 EDN08910.1 - 0.00092 18.0 0.1 0.01 14.5 0.0 2.1 2 0 0 2 2 2 1 Alkaline phosphatase PglZ PF08665.7 EDN08910.1 - 0.087 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 PglZ domain Siah-Interact_N PF09032.6 EDN08911.1 - 0.94 9.5 9.0 6.7 6.8 6.2 1.9 1 1 0 1 1 1 0 Siah interacting protein, N terminal FlxA PF14282.1 EDN08911.1 - 1.9 8.4 13.9 2.4 8.1 9.6 1.1 1 0 0 1 1 1 0 FlxA-like protein AAA PF00004.24 EDN08912.1 - 3.7e-41 140.4 0.0 6.1e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EDN08912.1 - 5.9e-15 54.9 0.1 2.5e-14 52.9 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_17 PF13207.1 EDN08912.1 - 2.2e-07 31.7 0.2 4.3e-05 24.3 0.0 3.3 2 1 0 3 3 2 1 AAA domain AAA_22 PF13401.1 EDN08912.1 - 3e-06 27.3 0.1 0.003 17.7 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.1 EDN08912.1 - 8.7e-06 25.2 0.1 0.012 15.0 0.0 3.5 2 2 1 3 3 3 1 AAA domain DUF815 PF05673.8 EDN08912.1 - 1.4e-05 24.1 0.0 0.0004 19.3 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 EDN08912.1 - 1.8e-05 24.2 0.0 3.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EDN08912.1 - 2.2e-05 23.6 0.0 3.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EDN08912.1 - 2.3e-05 24.2 0.0 5.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EDN08912.1 - 2.6e-05 24.3 0.0 0.0075 16.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 EDN08912.1 - 2.8e-05 24.2 0.0 0.00033 20.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EDN08912.1 - 3e-05 23.7 0.0 0.00011 21.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EDN08912.1 - 8.2e-05 21.4 0.0 0.00012 20.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus MIT PF04212.13 EDN08912.1 - 0.00018 21.3 0.8 0.0012 18.6 0.1 2.6 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain AAA_33 PF13671.1 EDN08912.1 - 0.00021 21.1 0.0 0.00077 19.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EDN08912.1 - 0.0032 17.3 0.0 0.0073 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EDN08912.1 - 0.0033 16.5 0.0 0.019 14.0 0.0 2.2 1 1 1 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EDN08912.1 - 0.0039 17.5 0.1 0.019 15.3 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.1 EDN08912.1 - 0.0068 16.0 0.0 0.018 14.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDN08912.1 - 0.0075 15.9 0.0 0.028 14.1 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EDN08912.1 - 0.0085 15.2 0.2 0.03 13.4 0.0 2.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EDN08912.1 - 0.01 15.5 0.2 0.12 12.0 0.0 2.2 2 1 1 3 3 2 1 Archaeal ATPase Torsin PF06309.6 EDN08912.1 - 0.012 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Torsin Parvo_NS1 PF01057.12 EDN08912.1 - 0.017 14.0 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 EDN08912.1 - 0.019 14.1 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 EDN08912.1 - 0.023 13.8 0.0 2.3 7.2 0.0 2.8 2 1 1 3 3 3 0 KaiC NACHT PF05729.7 EDN08912.1 - 0.024 14.3 0.0 0.35 10.5 0.0 2.2 1 1 1 2 2 2 0 NACHT domain ResIII PF04851.10 EDN08912.1 - 0.03 14.1 0.0 0.044 13.6 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit EF-1_beta_acid PF10587.4 EDN08912.1 - 0.042 13.9 6.2 0.1 12.7 2.9 2.5 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region CPT PF07931.7 EDN08912.1 - 0.068 12.7 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.21 EDN08912.1 - 0.078 12.4 0.0 0.23 10.9 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EDN08912.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EDN08912.1 - 0.08 12.9 0.0 0.2 11.7 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Guanylate_kin PF00625.16 EDN08912.1 - 0.13 11.6 0.0 0.52 9.7 0.0 1.9 1 1 0 1 1 1 0 Guanylate kinase ABC_tran PF00005.22 EDN08912.1 - 0.15 12.3 0.0 0.52 10.6 0.0 2.2 1 1 0 1 1 1 0 ABC transporter GSHPx PF00255.14 EDN08912.1 - 0.16 11.3 0.0 0.39 10.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione peroxidase PACT_coil_coil PF10495.4 EDN08913.1 - 5.2e-25 87.1 2.3 7.4e-25 86.6 0.4 2.3 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TSC22 PF01166.13 EDN08913.1 - 0.0096 15.8 0.6 0.0096 15.8 0.4 4.5 5 1 1 6 6 6 2 TSC-22/dip/bun family Shugoshin_N PF07558.6 EDN08913.1 - 1.5 8.5 6.9 0.67 9.7 0.6 3.3 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Spc24 PF08286.6 EDN08913.1 - 3.9 7.1 35.1 0.71 9.5 4.0 5.5 1 1 2 5 5 5 0 Spc24 subunit of Ndc80 Microtub_assoc PF07989.6 EDN08914.1 - 6.1e-28 96.4 7.8 6.1e-28 96.4 5.4 6.2 2 1 3 5 5 3 1 Microtubule associated CENP-F_leu_zip PF10473.4 EDN08914.1 - 0.00047 20.0 82.4 0.019 14.8 11.8 4.3 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EDN08914.1 - 0.0011 18.2 17.8 0.033 13.3 0.7 3.1 1 1 2 3 3 3 2 Reovirus sigma C capsid protein Mnd1 PF03962.10 EDN08914.1 - 0.0033 17.1 65.8 0.11 12.1 13.5 4.1 1 1 3 4 4 4 3 Mnd1 family OmpH PF03938.9 EDN08914.1 - 0.0039 17.1 14.6 0.0039 17.1 10.1 3.3 1 1 2 3 3 2 1 Outer membrane protein (OmpH-like) Cep57_CLD_2 PF14197.1 EDN08914.1 - 0.0046 16.8 13.9 0.0046 16.8 9.6 6.3 2 2 3 5 5 2 1 Centrosome localisation domain of PPC89 AAA_13 PF13166.1 EDN08914.1 - 0.012 14.0 54.2 0.026 13.0 27.6 2.2 1 1 1 2 2 2 0 AAA domain DUF848 PF05852.6 EDN08914.1 - 0.013 15.3 57.2 0.027 14.3 6.8 4.2 1 1 2 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) TBPIP PF07106.8 EDN08914.1 - 0.02 14.4 65.2 0.12 11.9 14.4 4.2 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PspA_IM30 PF04012.7 EDN08914.1 - 0.038 13.3 57.0 0.8 9.0 13.5 3.3 1 1 2 3 3 3 0 PspA/IM30 family WEMBL PF05701.6 EDN08914.1 - 0.13 10.6 70.2 0.085 11.3 33.5 2.8 1 1 1 2 2 2 0 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 EDN08914.1 - 0.14 11.9 73.1 0.76 9.5 9.8 4.9 1 1 5 6 6 6 0 TPR/MLP1/MLP2-like protein DUF342 PF03961.8 EDN08914.1 - 0.28 9.5 52.3 0.022 13.1 6.4 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF342) Filament PF00038.16 EDN08914.1 - 0.32 10.4 65.7 0.67 9.3 20.9 3.8 1 1 1 3 3 3 0 Intermediate filament protein Fez1 PF06818.10 EDN08914.1 - 0.35 10.8 62.9 0.18 11.8 20.3 2.5 1 1 1 2 2 2 0 Fez1 MscS_porin PF12795.2 EDN08914.1 - 0.35 10.1 66.1 0.21 10.8 19.0 3.4 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain IncA PF04156.9 EDN08914.1 - 0.82 9.2 87.7 0.026 14.1 24.9 4.0 1 1 2 4 4 4 0 IncA protein AAA_27 PF13514.1 EDN08914.1 - 1.7 6.2 60.5 4.3 4.8 26.2 2.2 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.6 EDN08914.1 - 1.9 7.0 67.2 1.2 7.7 11.2 3.4 1 1 3 4 4 4 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 EDN08914.1 - 3 7.6 30.3 3.7 7.3 1.7 4.1 1 1 2 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FliJ PF02050.11 EDN08914.1 - 3.1 7.8 63.7 0.28 11.2 7.3 5.0 2 1 2 4 4 4 0 Flagellar FliJ protein DUF3584 PF12128.3 EDN08914.1 - 3.1 5.0 71.1 0.059 10.6 22.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) DUF869 PF05911.6 EDN08914.1 - 3.5 5.7 66.0 1.2 7.3 22.8 2.9 1 1 2 3 3 3 0 Plant protein of unknown function (DUF869) ATG16 PF08614.6 EDN08914.1 - 3.8 7.3 73.5 1.2 8.8 15.1 4.8 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) DUF812 PF05667.6 EDN08914.1 - 3.8 5.8 60.7 0.11 11.0 22.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Syntaxin-6_N PF09177.6 EDN08914.1 - 3.9 7.9 43.5 0.58 10.5 5.0 4.7 1 1 4 5 5 5 0 Syntaxin 6, N-terminal IFT57 PF10498.4 EDN08914.1 - 4.1 6.0 52.6 0.19 10.4 7.7 3.5 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 Tropomyosin_1 PF12718.2 EDN08914.1 - 5.1 6.9 86.0 0.24 11.2 13.4 4.1 1 1 3 4 4 4 0 Tropomyosin like ERM PF00769.14 EDN08914.1 - 5.3 6.4 78.3 1.2 8.6 23.6 3.4 1 1 2 3 3 3 0 Ezrin/radixin/moesin family DUF972 PF06156.8 EDN08914.1 - 7.7 6.9 59.4 0.049 13.9 7.1 5.1 1 1 3 4 4 3 0 Protein of unknown function (DUF972) GAS PF13851.1 EDN08914.1 - 8 5.5 74.4 2.9 7.0 21.8 4.2 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding SGT1 PF07093.6 EDN08915.1 - 4.4e-137 457.9 16.7 9.8e-136 453.5 11.6 1.9 1 1 0 1 1 1 1 SGT1 protein GFO_IDH_MocA PF01408.17 EDN08916.1 - 5.9e-24 84.8 0.4 1.1e-23 83.9 0.3 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EDN08916.1 - 0.0043 17.3 0.0 0.011 15.9 0.0 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Noggin PF05806.7 EDN08916.1 - 0.057 12.6 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 Noggin AMMECR1 PF01871.12 EDN08917.1 - 8.9e-39 132.3 0.0 1.8e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 AMMECR1 Sporozoite_P67 PF05642.6 EDN08917.1 - 0.13 10.0 6.6 0.18 9.6 4.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.20 EDN08918.1 - 3.9e-68 229.4 0.0 5.7e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN08918.1 - 4.9e-28 97.9 0.0 6.5e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN08918.1 - 1.3e-06 27.6 0.0 2.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN08918.1 - 0.00026 20.7 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EDN08918.1 - 0.001 18.1 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EDN08918.1 - 0.04 13.2 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF1744 PF08490.7 EDN08919.1 - 1.9e-124 415.2 0.3 2.4e-98 329.3 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EDN08920.1 - 5.3e-59 199.6 1.4 5.3e-59 199.6 0.9 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.4 EDN08920.1 - 7.4e-10 38.7 0.1 1.9e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EDN08920.1 - 5.5e-05 23.0 0.1 0.00029 20.6 0.1 2.2 1 1 0 1 1 1 1 RNase_H superfamily DUF3767 PF12597.3 EDN08921.1 - 3e-16 59.1 0.0 4.6e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF543 PF04418.7 EDN08921.1 - 0.2 11.6 0.9 0.38 10.7 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Nop PF01798.13 EDN08922.1 - 1.8e-52 176.5 0.0 6.6e-52 174.7 0.0 1.9 2 0 0 2 2 2 1 Putative snoRNA binding domain NOP5NT PF08156.8 EDN08923.1 - 6.2e-20 71.1 0.1 1.3e-19 70.1 0.1 1.6 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Cpn60_TCP1 PF00118.19 EDN08924.1 - 1.2e-148 495.7 0.1 1.4e-148 495.5 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MOZ_SAS PF01853.13 EDN08925.1 - 5.9e-10 38.6 0.0 2.2e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 MOZ/SAS family IF2_N PF04760.10 EDN08925.1 - 0.0033 17.0 0.8 0.024 14.3 0.1 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region HTH_27 PF13463.1 EDN08925.1 - 0.04 14.2 0.3 0.077 13.3 0.2 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain Baculo_PEP_C PF04513.7 EDN08927.1 - 0.0039 17.0 1.4 0.0055 16.5 0.3 1.7 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus RRM_1 PF00076.17 EDN08927.1 - 0.0042 16.6 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CorA PF01544.13 EDN08927.1 - 0.071 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein tRNA-synt_2 PF00152.15 EDN08928.1 - 8.8e-53 179.2 0.0 5.1e-52 176.7 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDN08928.1 - 3.4e-07 30.0 0.0 5.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Gti1_Pac2 PF09729.4 EDN08933.1 - 3.5e-50 170.1 1.0 6.3e-49 166.0 0.7 2.1 1 1 0 1 1 1 1 Gti1/Pac2 family DUF2434 PF10361.4 EDN08934.1 - 2e-140 467.0 5.0 2.9e-140 466.5 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) DUF2678 PF10856.3 EDN08934.1 - 0.0028 17.3 0.8 0.0028 17.3 0.5 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2678) DKCLD PF08068.7 EDN08934.1 - 0.033 14.0 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 DKCLD (NUC011) domain DUF4149 PF13664.1 EDN08934.1 - 0.24 11.4 3.9 0.63 10.1 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) Fungal_trans_2 PF11951.3 EDN08936.1 - 1.5e-65 221.2 0.1 2e-65 220.8 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lsr2 PF11774.3 EDN08937.1 - 0.3 11.0 3.2 0.36 10.7 2.2 1.1 1 0 0 1 1 1 0 Lsr2 ABC_tran PF00005.22 EDN08938.1 - 1.3e-08 35.2 0.0 2.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 EDN08938.1 - 3.3e-07 29.6 1.0 4.6e-07 29.2 0.7 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane PF01061.19 EDN08939.1 - 2.6e-23 82.3 12.9 4.7e-23 81.4 8.9 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EDN08939.1 - 2e-20 73.5 0.0 3.7e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EDN08939.1 - 9.6e-08 32.3 1.4 0.00019 21.5 0.0 2.3 1 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EDN08939.1 - 0.12 12.3 0.1 0.59 10.0 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 EDN08939.1 - 0.13 11.9 1.3 0.44 10.1 0.2 2.1 2 0 0 2 2 2 0 NACHT domain Bys1 PF04681.7 EDN08940.1 - 2.2e-08 33.9 0.9 4e-08 33.1 0.7 1.3 1 1 0 1 1 1 1 Blastomyces yeast-phase-specific protein AA_permease_2 PF13520.1 EDN08941.1 - 3.7e-36 124.6 35.9 2.9e-35 121.6 13.8 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EDN08941.1 - 3e-10 39.0 24.7 1.4e-08 33.5 10.3 2.2 1 1 1 2 2 2 2 Amino acid permease CPSF100_C PF13299.1 EDN08942.1 - 4.5e-46 156.9 0.0 9.4e-46 155.9 0.0 1.6 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EDN08942.1 - 4.2e-16 59.0 0.0 1.8e-15 56.9 0.0 2.1 1 1 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.7 EDN08942.1 - 1.7e-06 27.7 0.0 3.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EDN08942.1 - 0.014 15.0 0.0 0.044 13.4 0.0 1.8 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily PGM_PMM_IV PF00408.15 EDN08942.1 - 0.053 13.5 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain Sec23_trunk PF04811.10 EDN08945.1 - 1.7e-53 181.4 0.0 6.3e-53 179.6 0.0 1.9 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EDN08945.1 - 9.9e-19 66.6 0.0 2e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EDN08945.1 - 1.5e-14 54.2 0.1 5.8e-14 52.3 0.1 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EDN08945.1 - 3.1e-07 30.0 0.0 6.1e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-H2C2_2 PF13465.1 EDN08946.1 - 5.4e-06 26.4 4.0 5.4e-06 26.4 2.8 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EDN08946.1 - 2e-05 24.6 11.4 0.0091 16.2 0.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN08946.1 - 6.7e-05 22.9 12.4 0.013 15.7 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger TylF PF05711.6 EDN08946.1 - 0.21 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) tRNA-synt_1 PF00133.17 EDN08947.1 - 0.069 11.1 0.0 0.08 10.9 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) ACC_central PF08326.7 EDN08947.1 - 0.14 10.2 0.0 0.16 10.0 0.0 1.1 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region COG5 PF10392.4 EDN08948.1 - 4e-42 143.3 0.0 3.1e-41 140.4 0.0 2.0 3 0 0 3 3 3 1 Golgi transport complex subunit 5 YscO PF07321.7 EDN08948.1 - 0.13 12.1 0.6 0.23 11.2 0.4 1.4 1 0 0 1 1 1 0 Type III secretion protein YscO SYS1 PF09801.4 EDN08949.1 - 1.9e-54 183.5 10.4 2.2e-54 183.3 7.2 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.7 EDN08949.1 - 0.028 14.1 2.8 0.028 14.1 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF485 RRM_1 PF00076.17 EDN08950.1 - 1.9e-10 40.2 0.0 4e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN08950.1 - 3.8e-07 29.9 0.0 1.3e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN08950.1 - 0.079 12.8 0.1 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RF-1 PF00472.15 EDN08951.1 - 4.4e-13 49.0 0.0 7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 EDN08951.1 - 0.0088 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein U3_assoc_6 PF08640.6 EDN08952.1 - 4.6e-29 100.0 0.8 5.5e-28 96.5 0.2 2.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EDN08952.1 - 0.0025 18.2 0.4 0.72 10.6 0.1 3.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.1 EDN08952.1 - 0.0038 16.3 0.7 0.0059 15.6 0.5 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN08952.1 - 0.054 13.8 0.2 0.34 11.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat NRDE-2 PF08424.5 EDN08952.1 - 0.12 11.2 0.1 0.18 10.6 0.1 1.4 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Suf PF05843.9 EDN08952.1 - 0.42 10.3 3.1 2.1 7.9 0.2 2.5 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Frag1 PF10277.4 EDN08953.1 - 3.8e-44 150.7 5.7 4.4e-44 150.5 4.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 EDN08954.1 - 0.00089 19.2 0.1 0.0045 16.9 0.0 1.8 1 1 1 2 2 2 1 Endonuclease/Exonuclease/phosphatase family AIF-MLS PF14962.1 EDN08955.1 - 0.015 14.9 0.3 0.018 14.7 0.2 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF1476 PF07345.6 EDN08955.1 - 0.033 14.4 2.6 0.049 13.8 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1476) DUF948 PF06103.6 EDN08955.1 - 0.056 13.2 0.1 0.078 12.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Host_attach PF10116.4 EDN08955.1 - 0.06 13.5 0.7 0.09 13.0 0.5 1.3 1 0 0 1 1 1 0 Protein required for attachment to host cells ATP-synt_B PF00430.13 EDN08955.1 - 0.27 11.0 5.7 0.075 12.8 1.9 1.5 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) FAD_binding_3 PF01494.14 EDN08957.1 - 7.4e-14 51.5 0.5 1.5e-06 27.5 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EDN08957.1 - 1.4e-05 24.1 0.1 3.2e-05 23.0 0.1 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EDN08957.1 - 4.6e-05 22.4 0.0 0.00068 18.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EDN08957.1 - 0.00055 20.0 0.1 0.0019 18.3 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN08957.1 - 0.0011 18.9 0.1 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDN08957.1 - 0.0014 18.5 0.1 0.0029 17.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDN08957.1 - 0.0028 16.5 0.0 0.0053 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EDN08957.1 - 0.0045 16.1 0.1 1 8.3 0.0 2.2 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase TrkA_N PF02254.13 EDN08957.1 - 0.0062 16.5 0.0 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.15 EDN08957.1 - 0.011 15.8 0.1 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ATS PF15445.1 EDN08957.1 - 0.014 14.5 0.2 0.021 13.9 0.1 1.2 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 Pyr_redox PF00070.22 EDN08957.1 - 0.016 15.5 0.0 0.068 13.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDN08957.1 - 0.026 13.0 0.2 0.13 10.6 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EDN08957.1 - 0.028 13.4 0.1 0.048 12.7 0.1 1.5 1 1 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 EDN08957.1 - 0.07 12.0 0.0 0.17 10.7 0.0 1.6 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EDN08957.1 - 0.13 12.0 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 EDN08957.1 - 0.14 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MutS_V PF00488.16 EDN08958.1 - 2.4e-95 318.4 0.0 3.8e-95 317.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EDN08958.1 - 1.3e-39 136.1 0.9 1.3e-39 136.1 0.6 1.8 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 EDN08958.1 - 4.5e-18 65.6 0.0 1.2e-17 64.2 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EDN08958.1 - 7e-16 58.1 1.1 2.1e-15 56.6 0.8 1.9 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 EDN08958.1 - 2.4e-14 53.3 0.0 1.5e-13 50.7 0.0 2.2 2 0 0 2 2 2 1 MutS domain I Gpi1 PF05024.10 EDN08959.1 - 3.7e-24 85.4 1.4 3.7e-24 85.4 0.9 1.6 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Myb_DNA-bind_6 PF13921.1 EDN08960.1 - 0.0025 17.8 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN08960.1 - 0.0079 16.2 0.2 0.026 14.5 0.1 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain DUF3315 PF11776.3 EDN08960.1 - 0.077 12.5 0.2 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3315) UPF0203 PF05254.7 EDN08961.1 - 6.2e-28 96.4 2.8 9.7e-28 95.8 1.9 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EDN08961.1 - 0.014 15.1 7.7 0.094 12.5 0.2 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 EDN08961.1 - 0.12 12.3 6.4 0.46 10.5 2.9 2.6 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.11 EDN08961.1 - 0.39 10.6 7.2 0.97 9.4 3.3 2.4 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein DUF19 PF01579.13 EDN08961.1 - 0.42 10.5 6.3 0.51 10.3 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF19) COX6B PF02297.12 EDN08961.1 - 1.1 9.2 9.0 0.82 9.7 1.1 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DUF1903 PF08991.5 EDN08961.1 - 3 8.0 6.8 2.6 8.2 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1903) DNA_pol_A_exo1 PF01612.15 EDN08962.1 - 4.5e-38 130.4 0.4 1e-37 129.3 0.2 1.6 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.7 EDN08962.1 - 6.8e-28 96.8 1.1 9e-27 93.2 0.3 3.0 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.18 EDN08962.1 - 1.4e-10 40.6 0.1 4.3e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 HRDC domain Methyltransf_11 PF08241.7 EDN08963.1 - 3.1e-08 33.9 0.0 2.8e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN08963.1 - 2.4e-07 31.3 0.0 3.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN08963.1 - 2.6e-06 27.7 0.0 4.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN08963.1 - 2.2e-05 24.0 0.0 0.00013 21.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN08963.1 - 0.00023 21.5 0.0 0.0047 17.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN08963.1 - 0.00026 20.7 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN08963.1 - 0.0058 16.6 0.0 0.0094 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CDK2AP PF09806.4 EDN08963.1 - 0.023 14.9 1.0 0.034 14.3 0.7 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1517 PF07466.6 EDN08963.1 - 3.5 6.5 6.3 6 5.7 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) RasGAP PF00616.14 EDN08965.1 - 2.7e-55 187.1 1.1 5.1e-55 186.2 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IncA PF04156.9 EDN08965.1 - 2.1 7.9 6.9 1.7 8.1 3.7 1.6 2 0 0 2 2 2 0 IncA protein CRAL_TRIO PF00650.15 EDN08966.1 - 2.4e-37 127.8 0.0 3.8e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDN08966.1 - 1.6e-10 40.9 0.8 4.7e-10 39.4 0.2 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EDN08966.1 - 7.2e-06 25.9 0.0 2.6e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Mis14 PF08641.7 EDN08967.1 - 1.6e-21 76.8 0.1 4.4e-21 75.4 0.1 1.9 1 1 0 1 1 1 1 Kinetochore protein Mis14 like RVT_1 PF00078.22 EDN08969.1 - 8.4e-19 67.7 0.0 2.1e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN08969.1 - 1.3e-16 60.7 0.2 9.6e-16 57.9 0.0 2.6 4 0 0 4 4 4 1 Integrase core domain zf-H2C2 PF09337.5 EDN08969.1 - 0.0037 16.6 0.1 0.01 15.1 0.0 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger FlxA PF14282.1 EDN08969.1 - 5.4 7.0 10.6 1.5 8.8 2.1 2.5 2 0 0 2 2 2 0 FlxA-like protein PPR_2 PF13041.1 EDN08970.1 - 2.8e-05 24.0 0.1 0.0061 16.5 0.0 2.4 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 EDN08970.1 - 0.00016 21.6 0.0 0.00069 19.7 0.0 2.2 1 0 0 1 1 1 1 Pentatricopeptide repeat domain KH_1 PF00013.24 EDN08970.1 - 0.00053 19.5 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 KH domain PPR PF01535.15 EDN08970.1 - 0.0088 15.9 0.1 0.023 14.6 0.1 1.8 1 0 0 1 1 1 1 PPR repeat DUF272 PF03312.10 EDN08970.1 - 0.094 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF272) Acetyltransf_1 PF00583.19 EDN08971.1 - 4.3e-11 42.6 0.3 3.3e-06 27.0 0.1 2.4 1 1 1 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EDN08971.1 - 3.7e-06 27.0 0.0 0.00026 21.1 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDN08971.1 - 1.1e-05 25.0 0.3 0.007 16.0 0.2 2.3 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EDN08971.1 - 1.4e-05 25.1 0.0 0.00092 19.3 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDN08971.1 - 0.0012 18.9 0.0 0.14 12.3 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EDN08971.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EDN08971.1 - 0.094 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EDN08971.1 - 0.13 12.1 0.1 0.38 10.6 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain LCAT PF02450.10 EDN08972.1 - 7.8e-97 324.6 0.0 9.5e-97 324.4 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 EDN08972.1 - 0.0029 17.5 0.0 0.012 15.5 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 EDN08972.1 - 0.0085 15.4 0.0 0.021 14.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_5 PF12695.2 EDN08972.1 - 0.027 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EDN08972.1 - 0.044 13.3 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF2305 PF10230.4 EDN08972.1 - 0.089 12.1 0.1 0.36 10.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) PAP2 PF01569.16 EDN08973.1 - 5.3e-12 45.5 6.5 5.3e-12 45.5 4.5 2.0 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EDN08973.1 - 4.2e-07 29.6 5.1 1.4e-06 27.9 3.6 1.8 1 1 0 1 1 1 1 PAP2 superfamily MFS_1 PF07690.11 EDN08976.1 - 1.3e-18 66.8 26.7 3.7e-16 58.7 7.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN08976.1 - 1.2e-17 63.6 11.7 1.9e-15 56.4 8.1 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter BT1 PF03092.11 EDN08976.1 - 0.015 14.0 0.7 1.9 7.1 0.0 2.6 1 1 2 3 3 3 0 BT1 family PIRT PF15099.1 EDN08976.1 - 0.096 11.9 0.1 0.25 10.5 0.0 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family RVT_2 PF07727.9 EDN08977.1 - 2.5e-15 56.1 0.0 3.9e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 EDN08977.1 - 6.6e-13 48.0 0.2 1.6e-12 46.9 0.2 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain 4F5 PF04419.9 EDN08978.1 - 4.8 7.9 14.6 39 5.0 10.1 2.4 1 1 0 1 1 1 0 4F5 protein family Choline_transpo PF04515.7 EDN08979.1 - 0.011 14.5 0.1 0.012 14.3 0.1 1.0 1 0 0 1 1 1 0 Plasma-membrane choline transporter S1FA PF04689.8 EDN08979.1 - 0.03 14.1 0.4 0.045 13.6 0.2 1.4 1 1 0 1 1 1 0 DNA binding protein S1FA DUF1312 PF07009.6 EDN08979.1 - 0.035 13.9 0.3 0.043 13.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1312) DUF4330 PF14221.1 EDN08979.1 - 0.051 13.4 0.2 0.056 13.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Tad PF13400.1 EDN08979.1 - 0.48 10.4 4.0 0.72 9.9 2.8 1.3 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like DUF4307 PF14155.1 EDN08979.1 - 0.65 9.7 3.9 1.4 8.7 2.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4307) DUF3951 PF13131.1 EDN08979.1 - 1.4 8.7 3.6 3.4 7.5 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3951) DUF1768 PF08719.6 EDN08981.1 - 4.6e-51 172.6 0.0 5.3e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) HNH_2 PF13391.1 EDN08983.1 - 0.00059 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease zf-HC2 PF13490.1 EDN08983.1 - 0.076 12.9 0.7 0.076 12.9 0.5 2.2 3 0 0 3 3 3 0 Putative zinc-finger DUF2306 PF10067.4 EDN08984.1 - 4.2e-12 46.1 6.4 4.2e-12 46.1 4.4 2.2 3 0 0 3 3 3 1 Predicted membrane protein (DUF2306) Cation_efflux PF01545.16 EDN08986.1 - 2.2e-24 86.0 10.4 2.8e-17 62.7 1.0 2.0 1 1 1 2 2 2 2 Cation efflux family Zip PF02535.17 EDN08986.1 - 0.045 12.7 9.1 0.065 12.2 6.3 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter NicO PF03824.11 EDN08986.1 - 0.093 12.0 4.0 0.058 12.6 1.8 1.4 1 1 0 1 1 1 0 High-affinity nickel-transport protein DUF2370 PF10176.4 EDN08986.1 - 0.12 11.6 0.1 4.3 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Golgin_A5 PF09787.4 EDN08987.1 - 0.11 10.9 7.4 0.19 10.2 5.1 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 cNMP_binding PF00027.24 EDN08989.1 - 3.2e-20 71.7 0.0 4.7e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Pex14_N PF04695.8 EDN08990.1 - 0.11 12.5 0.4 0.1 12.6 0.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fork_head PF00250.13 EDN08991.1 - 5.6e-16 58.3 0.0 1.1e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EDN08991.1 - 0.00015 21.8 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Snf7 PF03357.16 EDN08992.1 - 1.7e-33 115.3 20.7 1.7e-33 115.3 14.3 2.0 1 1 1 2 2 2 1 Snf7 Peptidase_S46 PF10459.4 EDN08992.1 - 0.84 7.9 12.0 0.9 7.8 8.3 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF3138 PF11336.3 EDN08992.1 - 1.4 7.0 7.3 1.5 6.8 4.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) IFT57 PF10498.4 EDN08992.1 - 2.8 6.6 15.7 0.33 9.6 7.6 1.7 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Ribosomal_60s PF00428.14 EDN08992.1 - 4.5 7.7 12.4 0.12 12.8 3.6 2.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein Ten1 PF12658.2 EDN08993.1 - 3.2e-51 172.2 0.0 3.7e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EDN08993.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit MFS_1 PF07690.11 EDN08994.1 - 3.1e-26 91.9 27.2 2.4e-24 85.6 10.8 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Corona_S2 PF01601.11 EDN08994.1 - 0.45 8.5 1.3 0.66 7.9 0.9 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Kelch_5 PF13854.1 EDN08995.1 - 3.4e-17 61.9 15.7 3.8e-08 33.1 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 EDN08995.1 - 3.1e-10 39.6 12.2 0.024 14.3 0.0 6.2 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EDN08995.1 - 2.2e-09 37.2 9.1 0.004 17.2 0.0 5.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EDN08995.1 - 2.8e-08 33.5 9.8 0.0077 16.3 0.1 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EDN08995.1 - 1.4e-07 31.0 3.8 0.087 12.6 0.0 4.8 4 0 0 4 4 4 2 Kelch motif SKG6 PF08693.5 EDN08995.1 - 3.7e-07 29.3 1.5 1e-06 27.9 1.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_1 PF01344.20 EDN08995.1 - 0.00015 21.2 11.0 0.58 9.7 0.1 4.8 5 0 0 5 5 5 3 Kelch motif BCAS2 PF05700.6 EDN08997.1 - 1.7e-54 184.6 1.5 1.9e-54 184.4 1.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Ceramidase_alk PF04734.8 EDN08998.1 - 1.1e-257 856.3 0.0 1.4e-257 856.0 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase EI24 PF07264.6 EDN09000.1 - 0.00095 18.6 17.9 0.0036 16.7 11.5 2.2 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) HAD_2 PF13419.1 EDN09001.1 - 2.4e-27 96.2 0.0 3e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN09001.1 - 0.0074 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like GTP_EFTU PF00009.22 EDN09003.1 - 2.6e-38 131.3 4.0 2.3e-37 128.2 2.7 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EDN09003.1 - 4.1e-28 97.4 0.1 1.3e-27 95.8 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EDN09003.1 - 1.6e-10 40.9 7.7 1.1e-05 25.4 0.2 3.8 4 0 0 4 4 4 2 Elongation factor Tu domain 2 IF2_N PF04760.10 EDN09003.1 - 2.6e-10 39.7 0.0 8e-10 38.2 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 EDN09003.1 - 1.5e-07 31.3 0.1 3.4e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDN09003.1 - 1.6e-05 25.4 0.1 4e-05 24.0 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN09003.1 - 7.6e-05 22.0 0.3 0.00016 20.9 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.5 EDN09003.1 - 0.00035 19.8 0.0 0.00084 18.6 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EDN09003.1 - 0.001 18.5 0.2 0.0036 16.7 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EDN09003.1 - 0.01 15.1 0.9 0.036 13.3 0.6 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.18 EDN09003.1 - 0.01 15.6 1.1 5.5 6.7 0.1 2.9 2 1 1 3 3 3 0 Dynamin family Ras PF00071.17 EDN09003.1 - 0.02 14.2 0.1 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 Ras family Mito_carr PF00153.22 EDN09004.1 - 3e-65 215.9 1.9 2.5e-21 75.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyoxalase_2 PF12681.2 EDN09005.1 - 0.035 14.7 0.0 0.042 14.4 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase-like domain Ribosomal_S2 PF00318.15 EDN09006.1 - 1.5e-50 171.3 0.0 3.2e-50 170.2 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S2 NACHT PF05729.7 EDN09007.1 - 1.2e-09 38.1 0.0 3.1e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EDN09007.1 - 2.4e-06 27.6 0.0 8.7e-06 25.8 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 EDN09007.1 - 0.00072 19.2 0.1 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 EDN09007.1 - 0.0016 18.5 0.1 0.01 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EDN09007.1 - 0.002 17.0 0.0 0.0048 15.7 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.1 EDN09007.1 - 0.011 16.0 0.1 0.21 11.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EDN09007.1 - 0.017 15.2 0.4 0.068 13.3 0.1 2.3 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EDN09007.1 - 0.029 13.9 0.5 0.066 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EDN09007.1 - 0.038 14.8 0.0 0.14 12.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDN09007.1 - 0.045 13.6 0.1 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EDN09007.1 - 0.05 13.7 0.1 0.36 11.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 EDN09007.1 - 0.07 12.8 0.0 0.07 12.8 0.0 2.2 3 0 0 3 3 2 0 Archaeal ATPase AAA_19 PF13245.1 EDN09007.1 - 0.13 12.0 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Pkinase PF00069.20 EDN09008.1 - 6.6e-05 22.1 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SURF6 PF04935.7 EDN09009.1 - 1.1e-53 181.7 34.5 1.1e-53 181.7 23.9 4.3 3 1 1 4 4 4 1 Surfeit locus protein 6 RRP14 PF15459.1 EDN09009.1 - 2.9e-23 81.6 1.0 2.9e-23 81.6 0.7 8.9 7 2 1 8 8 8 1 60S ribosome biogenesis protein Rrp14 CAF-1_p150 PF11600.3 EDN09009.1 - 7.8e-05 22.1 11.5 7.8e-05 22.1 7.9 4.2 3 1 1 4 4 4 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Fer4 PF00037.22 EDN09010.1 - 4.5e-13 48.2 16.2 5.3e-08 32.1 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EDN09010.1 - 1.4e-11 44.5 9.3 2.1e-11 43.9 6.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EDN09010.1 - 5.4e-09 35.7 10.0 1.3e-08 34.4 7.0 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EDN09010.1 - 6.9e-09 36.3 6.5 0.0002 22.0 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 EDN09010.1 - 7.5e-09 35.7 9.6 1.3e-08 34.9 6.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EDN09010.1 - 2.8e-08 33.6 19.4 5.2e-06 26.3 7.3 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EDN09010.1 - 1.3e-07 31.0 14.7 0.00044 20.0 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.1 EDN09010.1 - 2.4e-07 30.5 31.7 9.7e-05 22.1 8.6 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 EDN09010.1 - 1.6e-06 27.9 10.2 0.00028 20.9 0.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EDN09010.1 - 2.6e-06 27.0 16.4 0.0027 17.5 2.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EDN09010.1 - 1.3e-05 25.4 9.9 0.00061 20.0 7.4 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EDN09010.1 - 6.6e-05 23.2 9.4 0.024 15.0 0.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EDN09010.1 - 0.0041 17.4 14.8 0.13 12.6 2.9 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EDN09010.1 - 0.015 15.8 13.2 0.21 12.1 1.2 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EDN09010.1 - 0.11 13.1 16.1 0.16 12.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EDN09010.1 - 0.65 10.1 4.8 2.1 8.5 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PP-binding PF00550.20 EDN09011.1 - 1.4e-10 41.3 0.6 1.9e-10 40.8 0.4 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EDN09011.1 - 5e-05 23.2 0.2 7.9e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier GPP34 PF05719.6 EDN09012.1 - 6e-63 212.6 0.0 7.7e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) ADH_zinc_N_2 PF13602.1 EDN09013.1 - 1.1e-16 61.8 0.3 2e-16 61.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EDN09013.1 - 1.4e-06 27.9 1.3 6e-06 25.8 0.9 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN09013.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF2183 PF09949.4 EDN09014.1 - 2.3e-33 114.0 0.0 3.6e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) adh_short PF00106.20 EDN09015.1 - 4.1e-11 43.0 0.0 7.4e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN09015.1 - 4.9e-05 23.0 0.0 0.00012 21.7 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EDN09015.1 - 0.0045 16.4 0.0 0.015 14.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EDN09015.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Phytase PF02333.10 EDN09016.1 - 5.5e-19 68.1 0.2 3.5e-17 62.1 0.0 2.6 3 0 0 3 3 3 2 Phytase EGF_2 PF07974.8 EDN09016.1 - 3.9e-05 23.7 12.7 3.9e-05 23.7 8.8 2.5 2 0 0 2 2 2 1 EGF-like domain DUF1842 PF08896.5 EDN09016.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1842) hEGF PF12661.2 EDN09016.1 - 4.7 7.5 6.3 0.57 10.3 0.9 2.2 2 0 0 2 2 2 0 Human growth factor-like EGF CBS PF00571.23 EDN09019.1 - 9.2e-18 63.7 1.6 0.00066 19.4 0.0 5.6 5 0 0 5 5 5 5 CBS domain DUF3153 PF11353.3 EDN09020.1 - 2 7.7 5.8 4.3 6.7 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) VHS PF00790.14 EDN09022.1 - 1.3e-46 157.7 0.0 4.6e-46 155.9 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EDN09022.1 - 1e-26 92.8 1.7 3e-26 91.3 0.6 2.2 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 EDN09022.1 - 1.9e-17 63.5 0.1 5.4e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain DUF367 PF04034.8 EDN09023.1 - 1.2e-47 160.7 0.1 1.6e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EDN09023.1 - 3.1e-10 39.4 0.7 6.7e-10 38.3 0.5 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Cpn60_TCP1 PF00118.19 EDN09025.1 - 1.2e-36 126.4 0.0 1.3e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 EDN09026.1 - 3.8e-84 283.0 1.1 3.1e-83 280.0 0.7 1.9 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Osmo_CC PF08946.5 EDN09026.1 - 0.09 12.8 0.2 21 5.2 0.0 2.7 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Peptidase_C14 PF00656.17 EDN09027.1 - 1.2e-70 238.0 0.0 1.5e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EDN09027.1 - 1.6 8.5 0.0 1.6 8.5 0.0 2.9 5 0 0 5 5 5 0 Raptor N-terminal CASPase like domain F-box-like PF12937.2 EDN09028.1 - 1e-05 25.1 0.3 3.3e-05 23.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN09028.1 - 0.0015 18.0 0.8 0.0092 15.6 0.0 2.7 3 0 0 3 3 3 1 F-box domain LRR_6 PF13516.1 EDN09028.1 - 0.0081 16.1 1.5 2.1 8.6 0.0 4.5 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.28 EDN09028.1 - 1.1 9.5 5.4 27 5.2 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat SR-25 PF10500.4 EDN09028.1 - 2 7.8 10.3 5 6.5 7.1 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LRR_8 PF13855.1 EDN09028.1 - 9.2 6.1 7.8 54 3.6 0.1 4.4 4 1 1 5 5 5 0 Leucine rich repeat Ribosomal_S26e PF01283.14 EDN09029.1 - 1.5e-50 170.2 8.4 1.8e-50 169.9 5.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 EDN09029.1 - 0.039 14.2 0.2 8.1 6.8 0.0 2.3 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 EDN09029.1 - 0.06 13.7 0.6 1.6 9.1 0.3 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain CBS PF00571.23 EDN09030.1 - 2.3e-42 142.4 4.1 2.1e-11 43.4 0.0 4.3 4 0 0 4 4 4 4 CBS domain HEAT_2 PF13646.1 EDN09031.1 - 3.1e-18 65.8 8.2 1.7e-06 28.2 0.2 7.7 5 2 3 8 8 8 5 HEAT repeats HEAT PF02985.17 EDN09031.1 - 2.5e-17 61.3 11.4 0.0018 18.1 0.0 11.3 12 0 0 12 12 10 3 HEAT repeat HEAT_EZ PF13513.1 EDN09031.1 - 7.1e-14 51.8 14.6 2.6e-06 27.7 0.1 8.3 8 1 1 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EDN09031.1 - 2.5e-09 37.4 0.6 0.13 12.6 0.0 6.5 4 2 3 7 7 7 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EDN09031.1 - 8.7e-06 24.7 0.2 0.002 16.9 0.1 3.9 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal RIX1 PF08167.7 EDN09031.1 - 5.9e-05 22.7 0.0 0.01 15.4 0.0 4.2 3 1 2 5 5 5 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 EDN09031.1 - 0.00011 21.6 0.2 0.043 13.1 0.1 4.5 4 1 2 6 6 6 1 CLASP N terminal Arm PF00514.18 EDN09031.1 - 0.00023 20.8 1.2 6 6.8 0.0 5.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EDN09031.1 - 0.002 16.5 0.1 0.0055 15.0 0.1 1.8 1 0 0 1 1 1 1 Adaptin N terminal region IBN_N PF03810.14 EDN09031.1 - 0.0037 17.1 0.1 0.044 13.7 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF4042 PF13251.1 EDN09031.1 - 0.0049 16.3 0.1 3.4 7.0 0.0 4.4 3 1 0 3 3 3 1 Domain of unknown function (DUF4042) DUF3385 PF11865.3 EDN09031.1 - 0.0095 15.8 0.1 51 3.7 0.0 4.5 3 1 0 4 4 4 0 Domain of unknown function (DUF3385) Cnd1 PF12717.2 EDN09031.1 - 0.028 14.2 0.5 6.9 6.4 0.0 4.6 4 2 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DALR_1 PF05746.10 EDN09031.1 - 0.14 12.1 2.1 2.4 8.1 0.3 3.3 3 0 0 3 3 3 0 DALR anticodon binding domain Aconitase_C PF00694.14 EDN09032.1 - 2.7e-39 134.2 0.0 4.3e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase PF00330.15 EDN09032.1 - 3e-35 121.6 0.1 3.7e-35 121.2 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF2408 PF10303.4 EDN09033.1 - 5.7e-46 155.9 5.9 5e-35 120.5 0.0 4.2 3 1 1 4 4 4 3 Protein of unknown function (DUF2408) Rapamycin_bind PF08771.6 EDN09033.1 - 0.059 13.4 0.3 0.4 10.8 0.0 2.4 2 1 1 3 3 3 0 Rapamycin binding domain Spore_III_AB PF09548.5 EDN09033.1 - 0.076 12.7 2.6 0.3 10.8 0.1 2.6 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF3941 PF13081.1 EDN09033.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3941) FUSC PF04632.7 EDN09033.1 - 0.12 10.7 1.7 0.17 10.2 1.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ribosomal_60s PF00428.14 EDN09034.1 - 2e-23 82.5 6.6 2.5e-23 82.2 4.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Glyco_transf_21 PF13506.1 EDN09034.1 - 0.13 11.5 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 PQ-loop PF04193.9 EDN09035.1 - 1.8e-19 69.0 1.6 1.8e-19 69.0 1.1 2.6 2 0 0 2 2 2 1 PQ loop repeat DUF1282 PF06930.7 EDN09035.1 - 0.94 9.1 7.7 0.51 9.9 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Tcf25 PF04910.9 EDN09036.1 - 1.4e-75 254.5 0.0 2.4e-75 253.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_2 PF07719.12 EDN09036.1 - 0.00018 21.1 0.8 0.069 13.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 EDN09036.1 - 0.00072 19.7 0.1 0.18 12.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDN09036.1 - 0.0014 18.2 0.2 0.34 10.5 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.1 EDN09036.1 - 0.0044 16.9 0.0 3.9 7.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDN09036.1 - 0.018 15.6 0.2 5.7 7.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDN09036.1 - 0.07 13.8 0.1 2.8 8.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDN09036.1 - 0.12 12.8 0.2 1.2 9.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NST1 PF13945.1 EDN09036.1 - 0.43 10.6 8.3 0.031 14.3 2.3 1.7 2 0 0 2 2 2 0 Salt tolerance down-regulator PP2C PF00481.16 EDN09037.1 - 6.4e-41 140.4 0.0 1.1e-40 139.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EDN09037.1 - 6.1e-05 22.5 0.1 0.00014 21.3 0.1 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EDN09037.1 - 0.023 14.3 0.1 2 8.1 0.0 2.7 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) zf-H2C2_2 PF13465.1 EDN09038.1 - 2.7e-12 46.2 14.1 6.6e-08 32.4 0.2 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EDN09038.1 - 9.3e-12 44.5 14.6 1.1e-05 25.5 1.6 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN09038.1 - 2.2e-08 33.8 20.2 4e-05 23.6 1.8 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDN09038.1 - 0.00092 19.2 14.3 0.092 12.9 0.2 4.6 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDN09038.1 - 0.0023 18.0 7.7 0.012 15.7 0.2 3.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 EDN09038.1 - 0.21 11.8 0.4 0.56 10.5 0.3 1.7 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_6 PF13912.1 EDN09038.1 - 0.57 10.1 7.9 5.9 6.9 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger LIM PF00412.17 EDN09038.1 - 0.63 10.1 3.1 5.3 7.1 2.3 2.2 1 1 1 2 2 2 0 LIM domain Glycos_transf_1 PF00534.15 EDN09039.1 - 4.7e-18 65.2 0.0 8e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EDN09039.1 - 4.2e-08 33.4 0.0 1.1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EDN09039.1 - 0.029 14.0 0.5 0.14 11.8 0.0 2.4 3 0 0 3 3 3 0 Glycosyltransferase Family 4 Toxin_4 PF00706.12 EDN09039.1 - 0.18 12.0 0.3 2.3 8.4 0.1 2.7 3 0 0 3 3 3 0 Anenome neurotoxin DUF1087 PF06465.8 EDN09040.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) M20_dimer PF07687.9 EDN09041.1 - 1.3e-14 53.8 0.1 2.3e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EDN09041.1 - 8.4e-11 41.7 0.1 1.1e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Pkinase PF00069.20 EDN09042.1 - 2.3e-36 125.2 0.0 3.4e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN09042.1 - 2.4e-14 53.0 0.0 1.2e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN09042.1 - 1.9e-06 27.0 0.0 4.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN09042.1 - 0.0039 16.9 1.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EDN09043.1 - 8.6e-05 21.8 0.2 0.00012 21.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN09043.1 - 0.13 11.2 0.1 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Chorismate_synt PF01264.16 EDN09047.1 - 1.5e-129 431.4 0.0 1.8e-129 431.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Ima1_N PF09779.4 EDN09048.1 - 9.9e-48 161.9 4.3 9.9e-48 161.9 3.0 2.2 2 0 0 2 2 2 1 Ima1 N-terminal domain Tetraspannin PF00335.15 EDN09048.1 - 0.46 9.7 5.0 0.21 10.8 0.2 2.6 2 1 0 2 2 2 0 Tetraspanin family Zn_Tnp_IS1595 PF12760.2 EDN09048.1 - 0.95 9.3 7.2 0.13 12.1 1.8 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Alg14 PF08660.6 EDN09049.1 - 7e-48 162.8 0.0 3.7e-33 114.8 0.0 2.2 1 1 1 2 2 2 2 Oligosaccharide biosynthesis protein Alg14 like DUF605 PF04652.11 EDN09049.1 - 1.2 8.5 8.4 2 7.7 5.8 1.4 1 0 0 1 1 1 0 Vta1 like DUF1049 PF06305.6 EDN09049.1 - 4.3 6.8 7.5 0.1 12.0 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF3176 PF11374.3 EDN09051.1 - 3.4e-36 123.4 0.3 3.4e-36 123.4 0.2 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3176) PNK3P PF08645.6 EDN09052.1 - 4.4e-54 182.2 0.0 7.2e-54 181.5 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Med18 PF09637.5 EDN09052.1 - 1.6e-40 139.2 0.0 5.1e-40 137.5 0.0 1.9 1 1 0 1 1 1 1 Med18 protein AAA_33 PF13671.1 EDN09052.1 - 2.4e-12 46.9 0.0 2.4e-11 43.6 0.0 2.5 1 1 1 2 2 2 1 AAA domain HAD_2 PF13419.1 EDN09052.1 - 0.0011 19.1 0.2 0.11 12.7 0.0 2.8 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase AAA_22 PF13401.1 EDN09052.1 - 0.024 14.7 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EDN09052.1 - 0.094 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EDN09052.1 - 0.097 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2638 PF10937.3 EDN09053.1 - 2.3e-41 141.3 0.2 2.6e-41 141.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF647 PF04884.9 EDN09054.1 - 6.1e-28 97.6 0.9 2.2e-19 69.6 0.4 2.1 2 0 0 2 2 2 2 Vitamin B6 photo-protection and homoeostasis RGS PF00615.14 EDN09055.1 - 2.6e-13 50.1 0.0 4.2e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Aegerolysin PF06355.8 EDN09057.1 - 0.0001 22.1 0.0 0.00013 21.8 0.0 1.1 1 0 0 1 1 1 1 Aegerolysin Pkinase PF00069.20 EDN09058.1 - 2.8e-26 92.2 0.1 6.3e-26 91.0 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN09058.1 - 1.5e-07 30.7 0.1 3.6e-07 29.5 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase Rtt106 PF08512.7 EDN09059.1 - 1.2e-24 86.1 0.0 3.4e-24 84.6 0.0 1.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Cwf_Cwc_15 PF04889.7 EDN09059.1 - 2.4 7.7 9.6 3.8 7.1 6.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 EDN09059.1 - 8.3 4.7 14.2 12 4.2 9.8 1.1 1 0 0 1 1 1 0 Daxx Family KOW PF00467.24 EDN09060.1 - 0.017 14.7 1.6 0.017 14.7 1.1 2.1 2 0 0 2 2 2 0 KOW motif Ras PF00071.17 EDN09061.1 - 2e-55 186.6 0.0 2.3e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN09061.1 - 4.4e-15 56.2 0.0 6.8e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN09061.1 - 2.7e-06 26.7 0.0 4.4e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDN09061.1 - 0.0016 17.6 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EDN09061.1 - 0.026 13.6 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF1712 PF08217.6 EDN09062.1 - 1.2e-15 56.7 0.1 2e-14 52.7 0.0 2.5 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1712) Peptidase_U35_2 PF14550.1 EDN09062.1 - 0.056 13.0 0.7 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 Putative phage protease XkdF EMP24_GP25L PF01105.19 EDN09064.1 - 3.1e-26 92.2 0.0 4e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4179 PF13786.1 EDN09064.1 - 0.046 13.9 0.0 0.1 12.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Myb_DNA-bind_6 PF13921.1 EDN09065.1 - 0.013 15.5 0.0 0.039 14.0 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN09065.1 - 0.059 13.4 0.0 0.39 10.8 0.0 2.3 1 1 0 1 1 1 0 Myb-like DNA-binding domain Meth_synt_2 PF01717.13 EDN09066.1 - 5.5e-145 482.3 0.0 2.7e-140 466.9 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EDN09066.1 - 2e-112 375.5 0.0 1.6e-101 339.6 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Steroid_dh PF02544.11 EDN09067.1 - 2.4e-11 43.6 4.4 1.4e-07 31.4 0.8 3.7 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EDN09067.1 - 0.048 12.9 0.7 0.096 11.9 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Ufd2P_core PF10408.4 EDN09068.1 - 8e-186 619.0 7.7 1.4e-160 535.6 4.0 2.1 1 1 1 2 2 2 2 Ubiquitin elongating factor core U-box PF04564.10 EDN09068.1 - 3.4e-28 97.4 0.6 1.2e-27 95.6 0.4 2.0 1 0 0 1 1 1 1 U-box domain DUF972 PF06156.8 EDN09068.1 - 0.22 11.8 3.7 11 6.4 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DivIC PF04977.10 EDN09068.1 - 0.79 9.2 8.7 3.3 7.2 0.1 3.0 3 0 0 3 3 3 0 Septum formation initiator DUF1977 PF09320.6 EDN09069.1 - 9.7e-27 93.3 0.0 1.6e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EDN09069.1 - 1e-23 82.8 0.2 1.7e-23 82.1 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain ADP_ribosyl_GH PF03747.9 EDN09069.1 - 0.055 13.2 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase CTP_transf_2 PF01467.21 EDN09071.1 - 4.5e-05 23.5 0.1 0.00016 21.7 0.0 2.1 3 0 0 3 3 3 1 Cytidylyltransferase Plasmodium_HRP PF05403.6 EDN09073.1 - 4e-06 26.5 0.6 5.9e-06 26.0 0.4 1.1 1 0 0 1 1 1 1 Plasmodium histidine-rich protein (HRPII/III) Spore_coat_CotO PF14153.1 EDN09073.1 - 0.0019 17.6 12.2 0.0026 17.2 8.5 1.2 1 0 0 1 1 1 1 Spore coat protein CotO eIF3_subunit PF08597.5 EDN09073.1 - 0.0026 17.3 9.0 0.0033 17.0 6.3 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CENP-T PF15511.1 EDN09073.1 - 0.011 15.0 12.2 0.02 14.1 8.4 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ycf1 PF05758.7 EDN09073.1 - 0.011 13.5 5.0 0.012 13.3 3.4 1.0 1 0 0 1 1 1 0 Ycf1 DUF4045 PF13254.1 EDN09073.1 - 0.09 12.0 9.8 0.14 11.4 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Daxx PF03344.10 EDN09073.1 - 0.1 11.1 13.9 0.14 10.6 9.6 1.1 1 0 0 1 1 1 0 Daxx Family GNT-I PF03071.10 EDN09073.1 - 0.1 11.0 2.3 0.14 10.6 1.6 1.1 1 0 0 1 1 1 0 GNT-I family TP53IP5 PF15331.1 EDN09073.1 - 0.18 11.6 8.0 0.26 11.1 5.6 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 V_ATPase_I PF01496.14 EDN09073.1 - 0.53 8.0 2.1 0.63 7.8 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hid1 PF12722.2 EDN09073.1 - 0.66 7.5 4.6 0.78 7.3 3.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.9 EDN09073.1 - 0.7 9.5 6.4 0.96 9.1 4.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SAPS PF04499.10 EDN09073.1 - 0.96 8.0 6.9 1.3 7.5 4.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DDHD PF02862.12 EDN09073.1 - 1 9.1 9.5 1.5 8.5 6.6 1.3 1 0 0 1 1 1 0 DDHD domain AUX_IAA PF02309.11 EDN09073.1 - 1.4 8.6 7.1 2.1 8.0 4.9 1.2 1 0 0 1 1 1 0 AUX/IAA family F-protein PF00469.15 EDN09073.1 - 1.4 8.2 5.8 2.1 7.6 4.0 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef GAGA_bind PF06217.7 EDN09073.1 - 1.4 8.7 7.0 2 8.3 4.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 EDN09073.1 - 1.5 8.6 17.9 2.1 8.1 12.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 EDN09073.1 - 1.6 8.0 18.4 2.5 7.3 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CT47 PF15623.1 EDN09073.1 - 2.4 7.8 28.3 3.6 7.2 19.6 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Tim54 PF11711.3 EDN09073.1 - 2.9 6.3 9.6 4.8 5.6 6.6 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PBP_sp32 PF07222.7 EDN09073.1 - 2.9 6.9 14.5 5.7 6.0 10.1 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PPP4R2 PF09184.6 EDN09073.1 - 3.3 7.1 13.9 4.6 6.7 9.7 1.2 1 0 0 1 1 1 0 PPP4R2 VID27 PF08553.5 EDN09073.1 - 3.9 5.5 9.3 5.2 5.1 6.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Presenilin PF01080.12 EDN09073.1 - 4.4 6.0 9.2 8.2 5.1 6.4 1.4 1 0 0 1 1 1 0 Presenilin Dicty_REP PF05086.7 EDN09073.1 - 4.8 4.8 6.2 6.2 4.4 4.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1764 PF08576.5 EDN09073.1 - 5 7.9 10.9 9.2 7.1 7.6 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) CDC45 PF02724.9 EDN09073.1 - 7.5 4.4 12.1 10 4.0 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Rtf2 PF04641.7 EDN09073.1 - 7.5 5.6 14.9 11 5.1 10.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Ydc2-catalyt PF09159.5 EDN09074.1 - 1.6e-98 329.5 0.0 1.8e-98 329.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EDN09074.1 - 0.00066 19.5 0.0 4.1 7.2 0.0 3.4 3 0 0 3 3 3 2 Poxvirus A22 protein SR-25 PF10500.4 EDN09074.1 - 7.7 5.9 15.3 3.2 7.1 8.8 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Trehalase PF01204.13 EDN09075.1 - 3.2e-70 237.2 0.0 3.4e-61 207.4 0.0 2.1 2 0 0 2 2 2 2 Trehalase Trehalase_Ca-bi PF07492.6 EDN09075.1 - 5.8e-17 60.7 0.8 9.4e-17 60.0 0.6 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Ribosomal_S21 PF01165.15 EDN09076.1 - 0.027 13.9 0.0 3 7.3 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S21 CorA PF01544.13 EDN09077.1 - 1e-10 41.1 5.1 6.6e-10 38.4 3.5 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Tcp11 PF05794.8 EDN09078.1 - 2.6e-81 273.6 1.8 3.4e-81 273.2 1.2 1.1 1 0 0 1 1 1 1 T-complex protein 11 DUF2564 PF10819.3 EDN09078.1 - 0.03 14.4 0.2 0.03 14.4 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) SF-assemblin PF06705.6 EDN09078.1 - 0.44 9.6 2.7 5.5 6.0 0.1 2.3 2 0 0 2 2 2 0 SF-assemblin/beta giardin SOG2 PF10428.4 EDN09080.1 - 1.1e-67 228.5 1.4 1.1e-67 228.5 1.0 2.0 2 0 0 2 2 2 2 RAM signalling pathway protein MRP-S25 PF13741.1 EDN09081.1 - 3.1e-86 288.5 2.7 3.6e-86 288.3 1.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 PPR_3 PF13812.1 EDN09082.1 - 7.2e-09 35.2 0.5 0.59 10.5 0.0 4.6 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 EDN09082.1 - 0.032 14.2 0.8 0.51 10.3 0.2 2.7 2 1 0 2 2 2 0 PPR repeat family BTAD PF03704.12 EDN09082.1 - 0.098 12.9 0.1 0.46 10.7 0.0 2.2 3 0 0 3 3 3 0 Bacterial transcriptional activator domain SPO22 PF08631.5 EDN09082.1 - 0.14 11.2 0.1 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like PPR PF01535.15 EDN09082.1 - 1.5 9.0 3.2 21 5.3 0.3 3.5 4 0 0 4 4 4 0 PPR repeat Helicase_C PF00271.26 EDN09083.1 - 5.5e-19 67.8 0.0 1.9e-15 56.4 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.24 EDN09083.1 - 4.7e-17 62.0 0.0 3.2e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase KH_1 PF00013.24 EDN09084.1 - 5.3e-10 38.7 0.0 4.3e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EDN09084.1 - 6.1e-06 25.7 0.5 0.00041 19.9 0.1 2.9 2 0 0 2 2 2 1 KH domain ALS_ss_C PF10369.4 EDN09085.1 - 2.6e-19 68.7 0.0 5.5e-18 64.4 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EDN09085.1 - 5.2e-11 41.7 0.1 9.1e-11 41.0 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EDN09085.1 - 5.9e-09 35.6 0.0 1.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 EDN09085.1 - 0.048 13.3 0.1 12 5.6 0.0 2.5 2 0 0 2 2 2 0 ACT domain LEA_2 PF03168.8 EDN09087.1 - 8.7e-07 29.2 0.5 0.0039 17.5 0.0 4.2 3 1 0 3 3 3 2 Late embryogenesis abundant protein OTCace_N PF02729.16 EDN09088.1 - 3.7e-43 146.5 0.1 5.7e-43 145.9 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EDN09088.1 - 8.5e-39 132.9 0.0 1.2e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Gp_dh_N PF00044.19 EDN09088.1 - 0.057 13.3 0.1 7.2 6.5 0.0 2.5 2 1 1 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF3984 PF13136.1 EDN09089.1 - 5.8e-70 236.0 18.1 6.8e-70 235.8 12.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) CRPA PF05745.6 EDN09090.1 - 0.043 13.5 0.3 0.082 12.7 0.0 1.6 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF3753 PF12575.3 EDN09090.1 - 0.057 13.2 0.2 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Cut8_C PF08559.5 EDN09092.1 - 3e-51 173.0 0.0 4.5e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EDN09092.1 - 6.3e-17 61.0 0.8 1.5e-16 59.9 0.6 1.7 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 EDN09092.1 - 1.2e-14 54.0 6.5 2.3e-14 53.1 4.5 1.5 1 0 0 1 1 1 1 Cut8 proteasome-binding domain rRNA_proc-arch PF13234.1 EDN09093.1 - 2.7e-103 344.7 0.1 9.6e-103 342.9 0.0 1.9 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 EDN09093.1 - 3.9e-66 221.7 1.5 9e-66 220.5 1.0 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EDN09093.1 - 7.8e-22 77.5 0.2 2.4e-21 75.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN09093.1 - 4e-07 29.8 0.0 9.8e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN09093.1 - 0.029 14.2 0.0 0.22 11.3 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit COX7C PF02935.11 EDN09094.1 - 4.6e-09 35.9 0.3 6e-09 35.5 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc IKI3 PF04762.7 EDN09095.1 - 3.6e-156 521.5 0.0 4.3e-156 521.2 0.0 1.0 1 0 0 1 1 1 1 IKI3 family IKI3 PF04762.7 EDN09096.1 - 3.5e-78 263.4 2.6 1.5e-67 228.2 0.5 2.1 1 1 1 2 2 2 2 IKI3 family MutS_III PF05192.13 EDN09096.1 - 0.062 13.0 0.4 0.19 11.5 0.3 2.0 1 1 0 1 1 1 0 MutS domain III TPR_16 PF13432.1 EDN09096.1 - 3.2 8.5 10.4 0.28 11.9 0.5 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.21 EDN09097.1 - 6.6e-11 42.1 0.5 1.7e-10 40.8 0.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cyto_heme_lyase PF01265.12 EDN09098.1 - 1.1e-52 179.1 0.4 1.4e-52 178.9 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Syntaxin_2 PF14523.1 EDN09099.1 - 2.7e-23 81.9 2.7 2.7e-23 81.9 1.9 2.7 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EDN09099.1 - 5.3e-17 61.2 2.6 1.7e-16 59.6 1.8 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EDN09099.1 - 7.6e-05 22.8 0.3 7.6e-05 22.8 0.2 2.9 1 1 1 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 EDN09099.1 - 0.0009 18.7 0.4 0.0037 16.8 0.2 2.1 2 0 0 2 2 2 1 Synaptobrevin DUF1664 PF07889.7 EDN09099.1 - 0.087 12.6 2.3 7.3 6.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_S30 PF01577.11 EDN09099.1 - 0.094 12.1 0.8 0.14 11.4 0.6 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease DUF883 PF05957.8 EDN09099.1 - 0.098 13.0 10.7 0.35 11.3 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) T2SF PF00482.18 EDN09099.1 - 0.12 12.2 1.0 0.31 10.9 0.1 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F LMBR1 PF04791.11 EDN09099.1 - 0.27 9.7 1.4 0.33 9.4 1.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Ndc1_Nup PF09531.5 EDN09100.1 - 6.7e-85 285.7 0.0 7.5e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Y_phosphatase2 PF03162.8 EDN09101.1 - 1.3e-46 157.9 0.0 1.9e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EDN09101.1 - 2.1e-07 31.3 0.0 4.2e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EDN09101.1 - 1.6e-05 24.4 0.0 2.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDN09101.1 - 0.00071 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EDN09101.1 - 0.0049 16.3 0.0 0.009 15.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EDN09101.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate TatD_DNase PF01026.16 EDN09102.1 - 7.5e-35 120.3 0.0 3.1e-29 101.9 0.0 2.0 2 0 0 2 2 2 2 TatD related DNase BRCA-2_OB1 PF09103.5 EDN09102.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 FMN_dh PF01070.13 EDN09103.1 - 1.3e-108 363.0 0.0 1.6e-108 362.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EDN09103.1 - 5.2e-18 64.6 0.0 1e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EDN09103.1 - 4.9e-06 25.7 0.0 7.7e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EDN09103.1 - 0.00016 20.6 0.0 0.00049 19.1 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EDN09103.1 - 0.001 18.3 0.2 0.0025 17.0 0.0 1.5 1 1 1 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 EDN09103.1 - 0.0042 16.1 0.0 0.8 8.7 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 EDN09103.1 - 0.046 12.6 0.1 0.21 10.4 0.0 1.9 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase SAP PF02037.22 EDN09104.1 - 4.5e-10 38.7 0.1 8e-10 37.9 0.1 1.4 1 0 0 1 1 1 1 SAP domain Asp PF00026.18 EDN09106.1 - 1.9e-49 168.6 0.0 2.5e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EDN09106.1 - 0.033 14.6 0.0 7.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.1 EDN09106.1 - 0.066 12.7 0.0 0.19 11.2 0.0 1.8 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal DDE_1 PF03184.14 EDN09107.1 - 7.8e-52 175.5 0.0 1.4e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN09107.1 - 2.9e-11 43.0 0.0 5.4e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN09107.1 - 3.7e-06 26.7 0.0 8e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3945 PF13101.1 EDN09108.1 - 0.026 13.8 0.0 5.1 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) zf-C2H2_4 PF13894.1 EDN09110.1 - 2.6e-06 27.3 24.6 0.0014 18.8 1.8 5.4 6 0 0 6 6 6 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDN09110.1 - 0.00025 21.1 4.3 0.00025 21.1 3.0 3.7 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EDN09110.1 - 0.00053 20.1 24.1 0.0022 18.1 1.6 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDN09110.1 - 0.0023 18.1 0.4 0.0023 18.1 0.3 3.9 4 1 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.2 EDN09110.1 - 0.016 15.3 1.3 0.016 15.3 0.9 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-FCS PF06467.9 EDN09110.1 - 0.21 11.2 8.6 0.92 9.2 0.3 3.0 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-CHCC PF10276.4 EDN09110.1 - 0.52 10.1 4.2 2.5 8.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger domain Aa_trans PF01490.13 EDN09112.1 - 6.6e-41 140.1 12.9 9.3e-31 106.7 5.1 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein EamA PF00892.15 EDN09112.1 - 1.4 9.0 9.9 3.8 7.5 5.0 2.4 2 0 0 2 2 2 0 EamA-like transporter family Rad52_Rad22 PF04098.10 EDN09113.1 - 3.9e-35 120.8 2.9 1.4e-21 76.8 0.6 2.1 1 1 1 2 2 2 2 Rad52/22 family double-strand break repair protein Motile_Sperm PF00635.21 EDN09114.1 - 6.1e-26 90.2 0.3 1e-25 89.5 0.2 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain FixG_C PF11614.3 EDN09114.1 - 0.087 12.9 0.1 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase UBX PF00789.15 EDN09115.1 - 5.9e-07 29.4 0.3 1.9e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 UBX domain UBA PF00627.26 EDN09115.1 - 0.0018 18.0 0.1 0.0052 16.5 0.0 1.9 2 0 0 2 2 1 1 UBA/TS-N domain zf-C2H2 PF00096.21 EDN09115.1 - 0.017 15.4 0.2 0.029 14.7 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EDN09115.1 - 0.028 14.5 0.1 0.048 13.8 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding GATA PF00320.22 EDN09115.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 GATA zinc finger zf-C2H2_2 PF12756.2 EDN09115.1 - 0.18 11.9 0.3 0.18 11.9 0.2 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) SOBP PF15279.1 EDN09115.1 - 0.24 11.7 7.6 0.29 11.4 5.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Ycf1 PF05758.7 EDN09115.1 - 0.54 7.9 10.3 0.62 7.7 7.2 1.3 1 0 0 1 1 1 0 Ycf1 AAA_13 PF13166.1 EDN09115.1 - 0.72 8.2 16.8 0.95 7.8 11.6 1.2 1 0 0 1 1 1 0 AAA domain Rtf2 PF04641.7 EDN09115.1 - 0.75 8.9 20.3 1.1 8.3 14.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF342 PF03961.8 EDN09115.1 - 0.83 7.9 18.2 1.1 7.5 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Peptidase_C6 PF00851.13 EDN09115.1 - 1.2 7.6 10.1 1.6 7.2 7.0 1.1 1 0 0 1 1 1 0 Helper component proteinase Peptidase_S64 PF08192.6 EDN09115.1 - 1.3 7.2 6.6 1.5 7.0 4.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 CpXC PF14353.1 EDN09115.1 - 1.9 8.4 10.9 0.9 9.5 5.7 1.8 1 1 1 2 2 2 0 CpXC protein PLRV_ORF5 PF01690.12 EDN09115.1 - 3.4 6.6 14.2 4 6.4 9.9 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein APG6 PF04111.7 EDN09115.1 - 3.9 6.4 25.6 6.5 5.7 17.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 GAGA_bind PF06217.7 EDN09115.1 - 6.3 6.6 12.2 9.3 6.1 8.4 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family ACR_tran PF00873.14 EDN09115.1 - 6.8 3.9 6.4 8.7 3.5 4.5 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family HSP70 PF00012.15 EDN09118.1 - 1.6e-06 26.3 0.0 2.1e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein FA_desaturase PF00487.19 EDN09119.1 - 6.9e-11 42.0 4.0 8.6e-11 41.7 2.8 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Asn_synthase PF00733.16 EDN09120.1 - 1.9e-43 148.8 0.0 4.6e-43 147.5 0.0 1.7 1 0 0 1 1 1 1 Asparagine synthase Peptidase_M24 PF00557.19 EDN09120.1 - 6.1e-38 130.4 0.4 9.3e-38 129.8 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF2924 PF11149.3 EDN09120.1 - 0.45 10.5 2.2 0.78 9.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) GATase_7 PF13537.1 EDN09121.1 - 1.4e-36 124.9 0.0 2.2e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EDN09121.1 - 3.9e-28 98.0 0.0 9.8e-28 96.7 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain Asn_synthase PF00733.16 EDN09121.1 - 4.3e-14 52.6 0.1 6.1e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase DUF3700 PF12481.3 EDN09121.1 - 5e-08 32.4 0.0 8.2e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EDN09121.1 - 0.00043 19.2 0.0 0.00065 18.6 0.0 1.1 1 0 0 1 1 1 1 NAD synthase GATase_2 PF00310.16 EDN09121.1 - 0.00057 18.7 0.0 0.0033 16.1 0.0 1.8 1 1 1 2 2 2 1 Glutamine amidotransferases class-II QueC PF06508.8 EDN09121.1 - 0.068 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC UQ_con PF00179.21 EDN09122.1 - 1.9e-48 163.4 0.0 2.1e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDN09122.1 - 0.012 15.3 0.0 0.015 15.0 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 EDN09122.1 - 0.027 14.3 1.4 0.037 13.9 0.9 1.6 1 1 0 1 1 1 0 RWD domain YCII PF03795.9 EDN09123.1 - 1.9e-06 27.9 0.0 2.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 YCII-related domain Fcf1 PF04900.7 EDN09123.1 - 0.028 14.4 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Fcf1 T4_deiodinase PF00837.12 EDN09123.1 - 0.04 12.9 0.1 0.05 12.6 0.1 1.1 1 0 0 1 1 1 0 Iodothyronine deiodinase AMP-binding PF00501.23 EDN09124.1 - 1.4e-89 300.3 0.0 1.8e-89 300.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN09124.1 - 1.8e-06 28.8 0.0 5.8e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EDN09124.1 - 0.00055 18.5 0.0 0.0024 16.4 0.0 1.8 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Anp1 PF03452.9 EDN09126.1 - 5.4e-33 114.3 0.1 6.8e-33 113.9 0.1 1.1 1 0 0 1 1 1 1 Anp1 UCR_14kD PF02271.11 EDN09127.1 - 1.6e-47 159.5 1.4 1.8e-47 159.3 1.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.22 EDN09128.1 - 3.3e-51 170.9 0.0 5.3e-21 74.1 0.0 3.5 2 2 1 3 3 3 3 Mitochondrial carrier protein p450 PF00067.17 EDN09129.1 - 9.3e-06 24.4 0.1 1.1e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 T2SF PF00482.18 EDN09130.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F HEAT PF02985.17 EDN09131.1 - 0.0046 16.9 1.5 83 3.6 0.0 5.1 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.18 EDN09131.1 - 0.01 15.6 0.1 12 5.8 0.0 4.7 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EDN09131.1 - 0.019 15.2 1.3 2.1 8.7 0.1 4.0 4 2 0 4 4 4 0 HEAT repeats Cohesin_HEAT PF12765.2 EDN09131.1 - 0.059 13.3 0.1 0.64 10.0 0.0 2.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Clathrin PF00637.15 EDN09131.1 - 0.11 12.0 1.4 0.97 9.0 0.1 3.0 3 1 1 4 4 4 0 Region in Clathrin and VPS Pkinase PF00069.20 EDN09132.1 - 6.1e-61 205.8 0.0 1.9e-60 204.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN09132.1 - 3.6e-42 144.2 0.0 4.2e-41 140.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN09132.1 - 0.00067 18.7 0.0 0.0035 16.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Ribonuc_red_lgC PF02867.10 EDN09138.1 - 1.2e-110 370.6 0.0 2.5e-110 369.6 0.0 1.5 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EDN09138.1 - 8.3e-25 86.4 0.0 2.2e-24 85.0 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EDN09138.1 - 5e-17 62.1 0.0 1.1e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain BCS1_N PF08740.6 EDN09141.1 - 3.7e-40 137.5 0.0 6.3e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN09141.1 - 3.5e-20 72.5 0.0 1.7e-19 70.3 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN09141.1 - 0.0006 19.8 0.1 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EDN09141.1 - 0.008 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN09141.1 - 0.011 16.6 0.8 0.1 13.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EDN09141.1 - 0.022 14.6 0.0 0.22 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EDN09141.1 - 0.024 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.9 EDN09141.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EDN09141.1 - 0.1 12.1 0.3 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EDN09141.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain Peptidase_S10 PF00450.17 EDN09141.1 - 0.14 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase Lac_bphage_repr PF06543.7 EDN09142.1 - 0.12 11.9 1.5 0.42 10.1 1.0 1.8 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor Tn916-Xis PF09035.5 EDN09143.1 - 0.0073 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Excisionase from transposon Tn916 Methyltransf_23 PF13489.1 EDN09144.1 - 2.2e-09 37.2 0.0 2.6e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN09144.1 - 0.0013 18.3 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN09144.1 - 0.0091 16.5 0.0 0.013 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Glyco_tranf_2_3 PF13641.1 EDN09145.1 - 1.4e-19 70.8 0.0 1.9e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EDN09145.1 - 6.4e-06 25.9 0.0 1.5e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EDN09145.1 - 0.00046 19.5 0.0 0.001 18.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 APH PF01636.18 EDN09147.1 - 3.7e-09 36.6 0.0 1.4e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN09147.1 - 0.00034 20.2 0.0 0.00046 19.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EDN09147.1 - 0.0029 16.8 0.0 0.004 16.3 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EDN09147.1 - 0.011 14.3 0.0 0.021 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Kdo PF06293.9 EDN09147.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BTB PF00651.26 EDN09148.1 - 0.00015 21.7 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Cas_Csx9 PF09658.5 EDN09148.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) DegS PF05384.6 EDN09149.1 - 0.0033 16.6 0.3 0.0046 16.1 0.2 1.1 1 0 0 1 1 1 1 Sensor protein DegS Sec2p PF06428.6 EDN09149.1 - 0.013 15.3 1.0 0.019 14.7 0.7 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Med28 PF11594.3 EDN09149.1 - 0.015 15.4 0.3 0.023 14.9 0.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 28 HAUS5 PF14817.1 EDN09149.1 - 0.018 13.6 0.1 0.02 13.4 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 zf-C3HC4_3 PF13920.1 EDN09149.1 - 0.021 14.5 5.7 0.033 13.8 4.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NTR2 PF15458.1 EDN09149.1 - 0.057 12.6 0.3 0.066 12.4 0.2 1.1 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Muted PF14942.1 EDN09149.1 - 0.06 13.2 0.4 0.092 12.6 0.3 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein ERM PF00769.14 EDN09149.1 - 0.064 12.7 0.8 0.084 12.4 0.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family zf-RING_2 PF13639.1 EDN09149.1 - 0.08 12.7 5.2 0.19 11.6 3.6 1.6 1 1 0 1 1 1 0 Ring finger domain HALZ PF02183.13 EDN09149.1 - 0.088 12.5 3.1 0.59 9.8 0.3 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper ADIP PF11559.3 EDN09149.1 - 0.12 12.2 1.2 0.16 11.8 0.8 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2730 PF10805.3 EDN09149.1 - 0.15 11.8 0.3 0.34 10.6 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) ELFV_dehydrog PF00208.16 EDN09152.1 - 6.6e-80 268.2 0.7 7.8e-80 267.9 0.5 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EDN09152.1 - 4.9e-17 61.7 0.2 1.6e-16 60.1 0.1 1.9 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EDN09152.1 - 0.02 15.1 0.0 0.057 13.6 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Med5 PF08689.5 EDN09154.1 - 3.9e-248 825.9 0.0 3.8e-137 458.5 0.0 3.0 2 1 1 3 3 3 3 Mediator complex subunit Med5 DUF4219 PF13961.1 EDN09156.1 - 0.0054 16.1 0.2 0.013 14.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.18 EDN09156.1 - 1.5 8.9 4.3 2.5 8.2 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle ATP_bind_3 PF01171.15 EDN09157.1 - 3e-08 33.3 0.0 4.8e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EDN09157.1 - 0.0031 17.8 0.0 0.0065 16.7 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 EDN09157.1 - 0.046 13.1 0.7 0.046 13.1 0.5 2.1 2 0 0 2 2 2 0 RecR protein Nucleo_P87 PF07267.6 EDN09158.1 - 0.0015 17.3 3.5 0.0019 17.0 2.4 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 RNase_H PF00075.19 EDN09159.1 - 1.4e-13 51.3 0.0 2.6e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN09159.1 - 3.1e-06 26.8 0.0 6.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase-like DUF4242 PF14026.1 EDN09159.1 - 0.072 13.1 0.0 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4242) NifU_N PF01592.11 EDN09160.1 - 6.7e-52 174.7 0.0 9.3e-52 174.2 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain MIT PF04212.13 EDN09161.1 - 2.5e-10 40.0 0.4 8e-10 38.4 0.3 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DUF4398 PF14346.1 EDN09161.1 - 0.23 11.5 4.4 0.39 10.7 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Helicase_C PF00271.26 EDN09162.1 - 5.1e-12 45.4 0.0 1.2e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1041 PF06292.12 EDN09163.1 - 1 9.5 6.4 8 6.6 0.3 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) Tom37_C PF11801.3 EDN09163.1 - 5.4 6.8 8.0 0.79 9.5 0.3 2.3 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF573 PF04504.9 EDN09166.1 - 8.1e-07 29.2 0.3 2.1e-06 27.9 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF573 Myb_DNA-binding PF00249.26 EDN09166.1 - 3.4e-05 23.7 0.1 8.2e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN09166.1 - 0.00027 20.9 0.2 0.00049 20.1 0.1 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDN09166.1 - 0.00073 19.6 2.3 0.015 15.3 1.6 2.2 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Tom37_C PF11801.3 EDN09169.1 - 0.0087 15.9 0.7 0.0087 15.9 0.5 2.3 2 0 0 2 2 2 1 Tom37 C-terminal domain Myc_N PF01056.13 EDN09169.1 - 0.17 10.9 5.5 0.037 13.2 1.3 1.7 2 0 0 2 2 2 0 Myc amino-terminal region DUF3505 PF12013.3 EDN09170.1 - 8.3e-06 26.0 0.3 8.3e-06 26.0 0.2 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3505) RVT_2 PF07727.9 EDN09171.1 - 2.4e-71 239.5 0.0 3.9e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN09171.1 - 2.6e-16 59.8 0.0 1e-15 57.8 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EDN09171.1 - 1e-07 31.4 0.0 2.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2 PF14223.1 EDN09171.1 - 0.0093 15.7 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EDN09171.1 - 0.04 13.3 0.1 0.13 11.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) ATP11 PF06644.6 EDN09173.1 - 3e-79 266.2 0.0 3.5e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Abhydrolase_5 PF12695.2 EDN09174.1 - 1.1e-19 70.5 0.0 1.6e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN09174.1 - 5.3e-17 62.4 0.0 1.6e-15 57.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EDN09174.1 - 0.0001 21.8 0.0 0.00036 20.0 0.0 1.7 1 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EDN09174.1 - 0.0002 20.8 0.1 0.41 10.0 0.0 2.6 1 1 1 3 3 3 2 Phospholipase/Carboxylesterase AXE1 PF05448.7 EDN09174.1 - 0.001 17.6 0.2 0.29 9.6 0.1 3.0 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 EDN09174.1 - 0.0011 18.6 0.1 0.021 14.3 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EDN09174.1 - 0.0012 18.0 0.0 0.0039 16.4 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EDN09174.1 - 0.0015 18.2 0.0 0.049 13.3 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.8 EDN09174.1 - 0.0024 17.4 0.1 0.025 14.1 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 EDN09174.1 - 0.0038 17.0 0.0 0.009 15.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF1057 PF06342.7 EDN09174.1 - 0.0097 14.7 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DUF818 PF05677.7 EDN09174.1 - 0.013 14.2 0.0 0.018 13.7 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.8 EDN09174.1 - 0.024 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 EDN09174.1 - 0.052 12.9 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DLH PF01738.13 EDN09174.1 - 0.092 12.0 0.0 0.98 8.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF561 PF04481.7 EDN09174.1 - 0.14 11.0 0.0 6.4 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Peptidase_S28 PF05577.7 EDN09174.1 - 0.16 10.5 0.0 0.31 9.5 0.0 1.5 1 1 0 1 1 1 0 Serine carboxypeptidase S28 Proteasome PF00227.21 EDN09175.1 - 1.3e-34 119.1 2.0 8.5e-20 70.8 0.1 2.0 1 1 1 2 2 2 2 Proteasome subunit Cyclin PF08613.6 EDN09177.1 - 2.1e-39 135.2 1.4 1.7e-22 80.4 0.1 2.2 2 0 0 2 2 2 2 Cyclin RVT_1 PF00078.22 EDN09178.1 - 8.7e-22 77.5 0.0 1.9e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN09178.1 - 1.1e-17 64.2 0.5 3.3e-17 62.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EDN09178.1 - 3.4e-13 49.0 1.0 8.2e-13 47.8 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EDN09178.1 - 0.00016 21.0 0.1 0.00043 19.6 0.0 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Tudor-knot PF11717.3 EDN09178.1 - 0.0042 16.7 0.9 0.027 14.1 0.0 2.6 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain RVP PF00077.15 EDN09178.1 - 0.047 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EDN09178.1 - 0.077 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease APH PF01636.18 EDN09179.1 - 1.8e-05 24.6 0.0 2.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RVT_1 PF00078.22 EDN09180.1 - 1e-34 119.8 0.0 1.8e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN09180.1 - 3.4e-14 53.3 0.0 7.7e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN09180.1 - 2.8e-13 49.5 0.0 5.9e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase CEP44 PF15007.1 EDN09181.1 - 0.12 12.1 0.2 0.14 11.9 0.2 1.1 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 RabGAP-TBC PF00566.13 EDN09183.1 - 5.3e-29 101.2 0.0 8.4e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Telomerase_RBD PF12009.3 EDN09184.1 - 1.8e-42 144.5 0.2 5.7e-42 142.8 0.2 2.0 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EDN09184.1 - 2.1e-09 37.0 0.0 4.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGEF PF00621.15 EDN09185.1 - 3.6e-39 134.5 0.0 8.4e-39 133.3 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 EDN09185.1 - 1.4e-09 37.7 1.4 1.4e-09 37.7 1.0 2.4 2 1 0 2 2 2 1 BAR domain Peptidase_C48 PF02902.14 EDN09187.1 - 5.3e-15 55.6 0.1 1.9e-14 53.8 0.1 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DDE_1 PF03184.14 EDN09191.1 - 7.8e-52 175.5 0.0 3.5e-51 173.4 0.0 2.1 3 0 0 3 3 3 1 DDE superfamily endonuclease RB_B PF01857.15 EDN09191.1 - 0.053 13.0 0.6 0.09 12.2 0.4 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain HisG PF01634.13 EDN09193.1 - 6.2e-48 162.4 0.1 9.3e-48 161.8 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EDN09193.1 - 1.3e-28 98.7 0.1 2.4e-28 97.8 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EDN09193.1 - 0.071 12.6 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 NMT1/THI5 like Ribosomal_S28e PF01200.13 EDN09194.1 - 9.3e-33 111.7 1.0 9.9e-33 111.7 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MutS_V PF00488.16 EDN09195.1 - 9.1e-89 296.8 0.0 1.6e-88 296.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EDN09195.1 - 8.2e-39 133.4 0.6 1.4e-38 132.7 0.4 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EDN09195.1 - 1.1e-28 99.4 0.0 2.6e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EDN09195.1 - 1.7e-07 31.4 0.0 6.8e-07 29.4 0.0 2.1 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EDN09195.1 - 1.5e-05 25.0 0.1 6.8e-05 22.9 0.1 2.2 1 0 0 1 1 1 1 MutS family domain IV Prenyltrans PF00432.16 EDN09197.1 - 1.4e-56 187.6 8.0 4.2e-11 42.2 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EDN09197.1 - 1.7e-31 108.9 0.0 1.6e-13 51.0 0.0 3.8 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EDN09197.1 - 8.4e-11 41.8 0.0 0.00036 20.5 0.0 3.4 2 1 2 4 4 4 2 Prenyltransferase-like RhoGAP PF00620.22 EDN09198.1 - 2.8e-26 91.9 0.0 5e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.7 EDN09199.1 - 8e-54 181.5 0.0 1.1e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.4 EDN09200.1 - 1.4e-104 349.3 0.0 1.7e-104 349.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EDN09200.1 - 0.012 15.6 0.3 0.13 12.2 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA PF00004.24 EDN09201.1 - 4.7e-54 182.1 0.0 2.2e-43 147.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EDN09201.1 - 2.5e-29 101.1 0.2 4.5e-29 100.3 0.1 1.5 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EDN09201.1 - 2.4e-09 37.4 3.3 9.6e-05 22.4 0.1 3.6 2 1 1 3 3 3 2 AAA ATPase domain NACHT PF05729.7 EDN09201.1 - 7e-07 29.0 0.7 0.00053 19.6 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 EDN09201.1 - 3.1e-06 27.3 1.7 0.075 13.1 0.1 4.0 3 2 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EDN09201.1 - 4.6e-06 27.4 0.0 0.17 12.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EDN09201.1 - 1.6e-05 24.8 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EDN09201.1 - 2.2e-05 24.7 0.0 0.021 15.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDN09201.1 - 2.6e-05 23.3 0.0 0.012 14.6 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EDN09201.1 - 3e-05 23.5 0.1 0.05 13.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EDN09201.1 - 3.4e-05 23.5 0.0 0.074 12.8 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_2 PF07724.9 EDN09201.1 - 4.3e-05 23.4 0.0 0.13 12.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EDN09201.1 - 0.00014 21.0 0.0 0.28 10.2 0.0 2.6 3 0 0 3 3 3 2 Zeta toxin UPF0079 PF02367.12 EDN09201.1 - 0.00024 20.6 0.0 0.0037 16.9 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 EDN09201.1 - 0.00034 19.7 0.5 0.0083 15.1 0.0 2.4 1 1 1 2 2 2 1 KAP family P-loop domain AAA_25 PF13481.1 EDN09201.1 - 0.00075 18.9 2.9 6.6 6.0 0.1 4.3 2 2 1 4 4 4 0 AAA domain AAA_28 PF13521.1 EDN09201.1 - 0.00087 19.2 0.0 0.45 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDN09201.1 - 0.0027 17.4 0.1 1.9 8.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EDN09201.1 - 0.0032 17.3 0.0 0.34 10.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 EDN09201.1 - 0.0049 17.0 0.0 5.2 7.2 0.0 2.8 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 EDN09201.1 - 0.0051 17.1 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 1 ABC transporter Cytidylate_kin2 PF13189.1 EDN09201.1 - 0.015 15.2 0.0 2.7 7.8 0.0 3.1 3 0 0 3 3 3 0 Cytidylate kinase-like family Viral_helicase1 PF01443.13 EDN09201.1 - 0.016 14.7 0.0 0.45 10.0 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.8 EDN09201.1 - 0.017 13.8 0.0 1.4 7.5 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus Mg_chelatase PF01078.16 EDN09201.1 - 0.018 14.2 0.2 0.79 8.8 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.4 EDN09201.1 - 0.022 14.2 0.1 0.28 10.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.1 EDN09201.1 - 0.03 14.3 0.0 6.2 6.8 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EDN09201.1 - 0.033 13.9 0.0 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 NTPase KaiC PF06745.8 EDN09201.1 - 0.039 13.0 0.0 5.3 6.0 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF815 PF05673.8 EDN09201.1 - 0.05 12.5 0.0 0.73 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EDN09201.1 - 0.051 13.2 0.0 10 5.7 0.0 3.1 2 1 1 3 3 3 0 Archaeal ATPase SKI PF01202.17 EDN09201.1 - 0.065 13.1 0.0 4.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase cobW PF02492.14 EDN09201.1 - 0.4 10.0 3.9 2.7 7.3 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.18 EDN09202.1 - 1.2e-133 445.0 0.0 1.8e-133 444.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDN09202.1 - 1.6e-26 93.1 0.1 4.4e-26 91.7 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDN09202.1 - 5.8e-07 28.8 0.0 5.5e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDN09202.1 - 1.6e-05 24.6 0.0 4.7e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EDN09202.1 - 0.0061 16.9 0.1 0.028 14.8 0.1 2.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EDN09202.1 - 0.1 12.2 0.0 0.37 10.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) EGF_CA PF07645.10 EDN09203.1 - 6.1e-05 22.9 6.2 6.1e-05 22.9 4.3 1.9 2 0 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.2 EDN09203.1 - 0.00044 20.1 3.4 0.00044 20.1 2.4 1.8 2 0 0 2 2 2 1 EGF domain FXa_inhibition PF14670.1 EDN09203.1 - 0.0017 18.4 4.7 0.0017 18.4 3.3 2.3 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EDN09203.1 - 0.013 15.1 0.1 0.013 15.1 0.1 2.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like EGF PF00008.22 EDN09203.1 - 0.064 13.2 4.3 0.19 11.7 2.9 1.9 1 1 0 1 1 1 0 EGF-like domain AMP-binding PF00501.23 EDN09204.1 - 4.5e-86 288.8 0.0 5.9e-84 281.8 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN09204.1 - 1e-12 48.7 0.2 2e-12 47.8 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Bul1_C PF04426.7 EDN09205.1 - 8.7e-05 21.8 0.0 0.00016 21.0 0.0 1.4 1 0 0 1 1 1 1 Bul1 C terminus Nop25 PF09805.4 EDN09207.1 - 8.5e-39 132.7 9.2 8.5e-39 132.7 6.3 3.0 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) PSD4 PF07631.6 EDN09207.1 - 0.4 11.0 3.1 0.82 10.0 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) Tropomyosin_1 PF12718.2 EDN09208.1 - 6.8e-51 171.8 35.8 8e-51 171.6 24.8 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EDN09208.1 - 5.4e-11 42.0 32.6 1.3e-05 24.3 10.4 2.2 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.4 EDN09208.1 - 0.00019 21.3 9.1 0.00019 21.3 6.3 3.0 1 1 2 3 3 3 1 Predicted coiled-coil domain-containing protein FlaC_arch PF05377.6 EDN09208.1 - 0.0023 17.7 16.2 0.53 10.2 0.9 4.2 3 2 1 4 4 4 3 Flagella accessory protein C (FlaC) DUF4200 PF13863.1 EDN09208.1 - 0.0032 17.3 32.5 0.0091 15.9 10.2 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) EzrA PF06160.7 EDN09208.1 - 0.0052 15.0 24.4 0.0056 14.9 3.3 2.0 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA LPP PF04728.8 EDN09208.1 - 0.0055 16.4 5.4 0.9 9.3 0.6 3.3 2 2 1 3 3 3 1 Lipoprotein leucine-zipper Laminin_II PF06009.7 EDN09208.1 - 0.0068 16.1 18.2 0.013 15.2 4.3 2.2 1 1 1 2 2 2 1 Laminin Domain II TMF_DNA_bd PF12329.3 EDN09208.1 - 0.0075 16.0 35.8 11 5.8 8.1 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EDN09208.1 - 0.0088 15.6 32.0 0.092 12.3 22.2 2.2 1 1 0 1 1 1 1 IncA protein ERM PF00769.14 EDN09208.1 - 0.012 15.2 36.6 0.17 11.4 11.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ADIP PF11559.3 EDN09208.1 - 0.013 15.4 33.3 0.19 11.6 7.9 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 EDN09208.1 - 0.014 14.5 32.4 0.12 11.6 15.1 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 EDN09208.1 - 0.015 15.1 31.7 0.44 10.3 9.8 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Cast PF10174.4 EDN09208.1 - 0.015 13.3 28.8 0.016 13.2 19.9 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone APG6 PF04111.7 EDN09208.1 - 0.017 14.1 34.5 0.29 10.1 12.0 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EDN09208.1 - 0.017 14.9 33.0 0.13 12.1 3.2 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.8 EDN09208.1 - 0.018 14.9 27.5 0.18 11.7 13.3 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Reo_sigmaC PF04582.7 EDN09208.1 - 0.019 14.1 4.6 0.34 10.0 0.1 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF869 PF05911.6 EDN09208.1 - 0.021 13.1 24.5 0.38 8.9 5.7 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) TMF_TATA_bd PF12325.3 EDN09208.1 - 0.025 14.3 28.8 0.16 11.7 11.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2353 PF09789.4 EDN09208.1 - 0.033 13.4 23.0 0.045 13.0 15.9 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Myosin_tail_1 PF01576.14 EDN09208.1 - 0.078 10.6 34.4 0.73 7.4 23.9 1.8 1 1 0 1 1 1 0 Myosin tail Spc7 PF08317.6 EDN09208.1 - 0.083 11.5 27.6 0.056 12.1 10.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.5 EDN09208.1 - 0.085 12.9 18.8 0.5 10.4 4.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family WXG100 PF06013.7 EDN09208.1 - 0.096 12.7 15.9 1.3 9.1 0.2 3.4 2 1 1 3 3 3 0 Proteins of 100 residues with WXG MAD PF05557.8 EDN09208.1 - 0.1 10.6 27.1 0.21 9.6 18.8 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein NABP PF07990.7 EDN09208.1 - 0.13 11.4 6.7 0.14 11.3 4.6 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Herpes_pp85 PF04637.7 EDN09208.1 - 0.15 10.3 5.9 0.071 11.3 2.4 1.5 1 1 1 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Jnk-SapK_ap_N PF09744.4 EDN09208.1 - 0.16 11.9 27.2 0.095 12.6 13.2 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HAP1_N PF04849.8 EDN09208.1 - 0.17 10.7 27.9 1.5 7.7 12.0 2.3 1 1 1 2 2 2 0 HAP1 N-terminal conserved region BLOC1_2 PF10046.4 EDN09208.1 - 0.19 11.9 22.2 1.1 9.3 0.4 3.2 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.7 EDN09208.1 - 0.23 11.7 11.5 3.1 8.1 0.1 3.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.1 EDN09208.1 - 0.26 11.7 22.9 0.46 10.9 4.0 3.1 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF745 PF05335.8 EDN09208.1 - 0.34 10.3 21.9 0.53 9.7 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Atg14 PF10186.4 EDN09208.1 - 0.39 9.6 27.6 5.4 5.8 18.9 2.0 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin-6_N PF09177.6 EDN09208.1 - 0.39 11.1 20.6 8.1 6.9 2.8 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Striatin PF08232.7 EDN09208.1 - 0.4 10.9 25.5 0.45 10.8 11.7 2.3 1 1 0 2 2 2 0 Striatin family bZIP_1 PF00170.16 EDN09208.1 - 0.41 10.6 32.6 0.75 9.7 0.7 4.8 2 1 1 4 4 3 0 bZIP transcription factor Prefoldin_2 PF01920.15 EDN09208.1 - 0.6 9.8 32.9 0.12 12.1 1.1 4.1 2 1 2 4 4 4 0 Prefoldin subunit FlxA PF14282.1 EDN09208.1 - 0.66 9.9 23.5 7.2 6.6 0.2 2.9 1 1 0 2 2 2 0 FlxA-like protein IFT46_B_C PF12317.3 EDN09208.1 - 0.68 9.2 8.2 0.12 11.7 2.4 1.8 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Fmp27_WPPW PF10359.4 EDN09208.1 - 0.69 8.2 25.0 0.47 8.8 7.0 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF972 PF06156.8 EDN09208.1 - 0.8 10.0 26.2 0.85 9.9 8.6 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) BRE1 PF08647.6 EDN09208.1 - 0.84 9.6 30.3 0.31 11.0 4.9 2.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Uds1 PF15456.1 EDN09208.1 - 1 9.3 27.2 2.6 8.0 8.1 3.0 1 1 2 3 3 3 0 Up-regulated During Septation Vps5 PF09325.5 EDN09208.1 - 1 8.5 20.8 0.026 13.7 5.4 2.7 1 1 1 3 3 3 0 Vps5 C terminal like DUF812 PF05667.6 EDN09208.1 - 1 7.7 26.8 3.5 6.0 18.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) FUSC PF04632.7 EDN09208.1 - 1.1 7.5 8.8 1.4 7.2 6.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4201 PF13870.1 EDN09208.1 - 1.3 8.3 28.0 9.1 5.6 7.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.7 EDN09208.1 - 1.3 8.7 35.2 0.95 9.2 7.6 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Nup54 PF13874.1 EDN09208.1 - 1.4 8.5 24.5 1.4 8.5 7.9 2.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Lebercilin PF15619.1 EDN09208.1 - 1.4 8.3 34.8 3.2 7.1 10.5 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Sipho_Gp157 PF05565.6 EDN09208.1 - 1.6 8.3 20.5 0.95 9.0 4.4 2.1 1 1 1 2 2 2 0 Siphovirus Gp157 DUF724 PF05266.9 EDN09208.1 - 1.8 8.1 26.7 0.3 10.6 6.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CCDC155 PF14662.1 EDN09208.1 - 1.8 8.1 33.4 0.69 9.4 10.4 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF3584 PF12128.3 EDN09208.1 - 2 5.6 30.8 3.8 4.6 21.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 EDN09208.1 - 2.6 5.8 20.6 3.9 5.2 13.8 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.1 EDN09208.1 - 3.2 6.1 24.6 8.2 4.7 5.0 2.0 1 1 1 2 2 2 0 AAA domain DUF342 PF03961.8 EDN09208.1 - 3.3 6.0 26.2 0.4 9.0 6.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 EDN09208.1 - 3.7 7.3 13.1 13 5.6 3.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.10 EDN09208.1 - 3.9 7.0 33.7 0.43 10.1 6.2 4.3 2 1 2 4 4 4 0 Septum formation initiator TMCO5 PF14992.1 EDN09208.1 - 4 6.5 25.6 3.4 6.7 4.3 2.3 1 1 0 2 2 2 0 TMCO5 family DUF4618 PF15397.1 EDN09208.1 - 4.2 6.6 24.9 2.7 7.2 1.2 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) DUF3450 PF11932.3 EDN09208.1 - 4.4 6.4 26.3 7.2 5.7 3.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) Mnd1 PF03962.10 EDN09208.1 - 4.5 6.8 31.2 7.5 6.1 9.3 2.1 1 1 1 2 2 2 0 Mnd1 family HSP70 PF00012.15 EDN09208.1 - 4.7 5.0 17.6 7.2 4.3 12.2 1.3 1 0 0 1 1 1 0 Hsp70 protein YjcZ PF13990.1 EDN09208.1 - 4.8 6.2 17.4 2.2 7.3 7.7 2.0 1 1 1 2 2 2 0 YjcZ-like protein bZIP_2 PF07716.10 EDN09208.1 - 5 7.0 38.0 0.76 9.6 1.6 5.4 2 2 3 5 5 5 0 Basic region leucine zipper DUF3287 PF11690.3 EDN09208.1 - 5.5 7.0 13.5 10 6.1 2.7 3.3 1 1 2 3 3 2 0 Protein of unknown function (DUF3287) DUF3461 PF11944.3 EDN09208.1 - 6.5 6.6 12.5 7.4 6.4 3.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3461) DUF904 PF06005.7 EDN09208.1 - 6.8 7.0 36.7 13 6.1 8.5 3.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) SlyX PF04102.7 EDN09208.1 - 7 7.1 22.7 9.1 6.7 4.0 3.8 2 2 2 4 4 4 0 SlyX Syntaxin PF00804.20 EDN09208.1 - 7.8 6.7 21.9 2.8e+03 -1.5 15.2 2.5 1 1 0 1 1 0 0 Syntaxin RE_AccI PF09545.5 EDN09209.1 - 0.06 11.8 0.0 0.086 11.3 0.0 1.1 1 0 0 1 1 1 0 AccI restriction endonuclease CMAS PF02353.15 EDN09210.1 - 7.5e-62 208.8 0.1 9.2e-62 208.5 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EDN09210.1 - 2.6e-11 43.5 0.0 5.2e-11 42.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN09210.1 - 1.2e-07 32.1 0.0 2.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN09210.1 - 3.8e-05 23.7 0.0 0.00011 22.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN09210.1 - 0.0002 21.6 0.0 0.00045 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN09210.1 - 0.00023 21.7 0.0 0.00093 19.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN09210.1 - 0.0004 19.9 0.0 0.00068 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN09210.1 - 0.00062 20.1 0.0 0.0014 19.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN09210.1 - 0.00074 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 EDN09210.1 - 0.0068 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.14 EDN09210.1 - 0.036 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ATP-synt_S1 PF05827.7 EDN09211.1 - 3.7e-43 147.8 0.0 4.3e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Mucin PF01456.12 EDN09212.1 - 0.0002 21.1 1.9 0.00041 20.1 1.3 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein GRP PF07172.6 EDN09212.1 - 3.2 8.2 0.0 3.2 8.2 0.0 2.9 2 1 0 2 2 2 0 Glycine rich protein family EXS PF03124.9 EDN09213.1 - 4.3e-88 295.6 6.5 5.2e-88 295.3 4.5 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.9 EDN09214.1 - 2.4e-33 115.5 3.2 1.8e-17 63.5 0.7 2.1 1 1 1 2 2 2 2 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EDN09214.1 - 1.1e-10 41.2 9.4 1.7e-10 40.5 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDN09214.1 - 1.2e-10 40.7 7.9 1.9e-10 40.1 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN09214.1 - 2.3e-10 40.3 9.1 3.6e-10 39.6 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN09214.1 - 2.4e-09 36.7 5.1 3.7e-09 36.1 3.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN09214.1 - 1.4e-08 34.3 6.6 2.1e-08 33.7 4.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EDN09214.1 - 1.5e-06 27.9 8.5 2.6e-06 27.1 5.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EDN09214.1 - 2.5e-05 23.9 1.9 7e-05 22.4 1.4 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 EDN09214.1 - 0.00013 21.7 2.8 0.00029 20.5 1.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EDN09214.1 - 0.0002 21.4 8.2 0.00052 20.0 5.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EDN09214.1 - 0.042 13.6 2.3 0.042 13.6 1.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EDN09214.1 - 0.18 11.4 8.2 0.4 10.3 5.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EDN09214.1 - 0.41 10.2 5.7 0.73 9.3 3.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit IBR PF01485.16 EDN09214.1 - 1.4 8.8 7.1 4.2 7.3 4.9 1.8 1 1 0 1 1 1 0 IBR domain DNA_pol_A_exo1 PF01612.15 EDN09215.1 - 1.4e-14 54.0 0.1 2.6e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease NrfD_2 PF14589.1 EDN09215.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Polysulfide reductase LSM PF01423.17 EDN09216.1 - 7.5e-17 60.6 0.2 3.8e-15 55.1 0.0 2.0 2 0 0 2 2 2 2 LSM domain AA_permease PF00324.16 EDN09218.1 - 3.7e-143 477.3 40.1 4.3e-143 477.1 27.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDN09218.1 - 2.8e-37 128.2 38.8 3.7e-37 127.8 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AP_endonuc_2 PF01261.19 EDN09219.1 - 4.7e-09 35.8 0.0 7.2e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AMP-binding PF00501.23 EDN09220.1 - 1.7e-41 142.0 0.0 8.5e-37 126.5 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme TFIIA_gamma_N PF02268.11 EDN09220.1 - 0.1 12.2 0.0 0.3 10.6 0.0 1.8 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain RhoGAP PF00620.22 EDN09221.1 - 2.3e-16 59.7 0.5 6.5e-16 58.3 0.4 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EDN09221.1 - 1.1e-13 51.1 1.6 2.2e-13 50.2 0.0 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EDN09221.1 - 1.2e-12 47.3 0.0 3.1e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Phage_Gp14 PF10666.4 EDN09221.1 - 0.056 13.3 1.1 0.1 12.4 0.1 1.8 2 0 0 2 2 2 0 Phage protein Gp14 Methyltransf_23 PF13489.1 EDN09222.1 - 2.1e-17 63.3 0.0 2.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN09222.1 - 3.5e-11 43.6 0.0 1e-09 38.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN09222.1 - 2.2e-09 37.1 0.0 5.2e-08 32.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN09222.1 - 1.5e-08 34.9 0.0 6.4e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN09222.1 - 1.2e-07 32.1 0.0 2e-06 28.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN09222.1 - 7.3e-05 22.7 0.2 0.00046 20.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EDN09222.1 - 0.00021 20.7 0.0 0.019 14.3 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EDN09222.1 - 0.0012 19.1 0.0 0.0033 17.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDN09222.1 - 0.0066 15.6 0.0 0.014 14.5 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EDN09222.1 - 0.0067 16.4 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EDN09222.1 - 0.0072 15.3 0.0 0.021 13.8 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EDN09222.1 - 0.042 12.9 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 EDN09222.1 - 0.057 12.6 0.0 0.098 11.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_16 PF10294.4 EDN09222.1 - 0.14 11.6 0.0 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase p450 PF00067.17 EDN09223.1 - 3.5e-45 154.4 0.0 4.8e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AAA_22 PF13401.1 EDN09224.1 - 2.4e-14 53.5 0.0 5.6e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EDN09224.1 - 2.1e-13 50.6 0.0 3.8e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN09224.1 - 2.6e-11 43.8 0.2 1.6e-10 41.2 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.6 EDN09224.1 - 8.3e-05 22.2 0.0 0.00032 20.3 0.0 1.9 2 0 0 2 2 2 1 CDC6, C terminal NACHT PF05729.7 EDN09224.1 - 0.00061 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain TIP49 PF06068.8 EDN09224.1 - 0.0011 17.8 0.0 0.0017 17.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 EDN09224.1 - 0.0069 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 EDN09224.1 - 0.013 16.3 0.0 0.021 15.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDN09224.1 - 0.017 14.9 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EDN09224.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 EDN09224.1 - 0.031 13.2 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF815 PF05673.8 EDN09224.1 - 0.031 13.2 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EDN09224.1 - 0.047 12.5 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 EDN09224.1 - 0.062 13.1 0.0 0.18 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain UBA_4 PF14555.1 EDN09225.1 - 5.4e-14 51.4 0.0 1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 EDN09225.1 - 4.4e-12 45.8 0.0 9.1e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 EDN09225.1 - 1.1e-06 28.6 0.0 4e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 UBX domain Pkinase PF00069.20 EDN09226.1 - 1.5e-42 145.5 0.3 2.5e-29 102.2 0.0 2.7 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN09226.1 - 3.4e-29 101.6 0.0 4.5e-20 71.8 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase BAF1_ABF1 PF04684.8 EDN09226.1 - 8.9 5.0 13.5 14 4.4 9.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor p450 PF00067.17 EDN09227.1 - 9.2e-14 50.8 0.0 1.1e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L39 PF00832.15 EDN09227.1 - 0.059 12.8 0.1 0.15 11.5 0.1 1.7 1 0 0 1 1 1 0 Ribosomal L39 protein p450 PF00067.17 EDN09228.1 - 0.045 12.2 0.0 0.05 12.1 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 ADH_N PF08240.7 EDN09230.1 - 6.2e-24 83.8 1.6 1.3e-23 82.8 1.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN09230.1 - 6.5e-21 74.2 0.1 1e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PALP PF00291.20 EDN09230.1 - 0.042 13.0 2.0 0.083 12.1 0.1 1.9 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme DUF2852 PF11014.3 EDN09233.1 - 0.2 11.6 4.6 0.48 10.4 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) zf-H2C2_2 PF13465.1 EDN09234.1 - 5.8e-13 48.4 16.6 9e-08 32.0 1.3 4.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EDN09234.1 - 2e-07 30.9 33.8 0.0066 16.7 0.1 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 EDN09234.1 - 0.015 14.9 1.8 0.043 13.4 1.3 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 EDN09234.1 - 0.016 15.5 0.2 0.016 15.5 0.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger DUF1192 PF06698.6 EDN09234.1 - 0.022 14.5 0.1 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) zf-C2H2_6 PF13912.1 EDN09234.1 - 0.052 13.4 0.1 0.052 13.4 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger DZR PF12773.2 EDN09234.1 - 0.32 10.8 6.9 4.8 7.0 4.8 2.3 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EDN09234.1 - 0.79 9.7 10.2 2.3 8.2 2.1 3.1 1 1 1 2 2 2 0 Zinc ribbon domain zf-RING_3 PF14369.1 EDN09234.1 - 3.3 7.7 7.7 15 5.7 0.1 2.9 2 1 0 2 2 2 0 zinc-finger zf-C2H2_jaz PF12171.3 EDN09234.1 - 8.9 6.5 24.1 1.5 9.0 0.2 4.6 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF3074 PF11274.3 EDN09235.1 - 8.6e-47 159.1 0.0 1.3e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Methyltransf_23 PF13489.1 EDN09236.1 - 6.3e-21 74.7 0.0 9.3e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN09236.1 - 2.9e-10 40.5 0.0 5.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN09236.1 - 1.8e-08 34.9 0.2 6e-07 30.0 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN09236.1 - 4.5e-08 32.8 0.0 0.0017 17.9 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EDN09236.1 - 6e-06 26.6 0.0 9.7e-05 22.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN09236.1 - 2.4e-05 23.5 0.0 0.004 16.2 0.0 2.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EDN09236.1 - 0.00024 21.4 0.0 0.0011 19.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EDN09236.1 - 0.0014 17.7 0.0 0.017 14.1 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EDN09236.1 - 0.002 18.1 0.1 0.0046 16.9 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 EDN09236.1 - 0.026 13.5 0.0 0.052 12.6 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 EDN09236.1 - 0.03 13.6 0.0 0.082 12.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EDN09236.1 - 0.07 13.1 0.0 0.35 10.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EDN09236.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 EDN09236.1 - 0.12 11.5 0.0 0.25 10.5 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase Stk19 PF10494.4 EDN09238.1 - 1.1e-71 241.1 0.0 1.3e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Glyco_transf_20 PF00982.16 EDN09239.1 - 4.3e-149 497.0 0.9 6.1e-149 496.5 0.2 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EDN09239.1 - 3e-40 137.6 0.0 5.4e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 EDN09239.1 - 0.0092 15.4 0.8 0.02 14.4 0.5 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain 4HBT PF03061.17 EDN09240.1 - 1.3e-09 38.0 0.1 2.1e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily PCI PF01399.22 EDN09242.1 - 5.2e-11 42.7 0.0 1.3e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 PCI domain K_channel_TID PF07941.6 EDN09242.1 - 0.033 14.4 11.5 0.1 12.8 8.0 1.9 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain ADK PF00406.17 EDN09243.1 - 1.6e-41 141.7 0.5 1.4e-21 76.9 0.2 2.1 1 1 1 2 2 2 2 Adenylate kinase AAA_18 PF13238.1 EDN09243.1 - 9e-11 42.1 0.0 1.6e-10 41.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDN09243.1 - 7.1e-08 32.4 0.6 3.9e-07 30.0 0.4 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN09243.1 - 1.2e-05 26.0 0.1 4.1e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain MAGE_N PF12440.3 EDN09243.1 - 0.0063 16.7 6.2 0.0063 16.7 4.3 2.0 2 0 0 2 2 2 1 Melanoma associated antigen family N terminal PAXNEB PF05625.6 EDN09243.1 - 0.01 14.6 0.6 0.017 14.0 0.4 1.2 1 0 0 1 1 1 0 PAXNEB protein Thymidylate_kin PF02223.12 EDN09243.1 - 0.021 14.1 8.3 0.36 10.1 0.0 3.0 2 1 1 3 3 3 0 Thymidylate kinase RAB3GAP2_N PF14655.1 EDN09243.1 - 0.024 13.6 0.9 0.034 13.1 0.7 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pex26 PF07163.7 EDN09243.1 - 0.039 12.8 0.6 0.053 12.4 0.4 1.1 1 0 0 1 1 1 0 Pex26 protein TMEM154 PF15102.1 EDN09243.1 - 0.051 13.2 0.1 0.051 13.2 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family AAA_19 PF13245.1 EDN09243.1 - 0.075 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain FAM176 PF14851.1 EDN09243.1 - 0.087 12.5 0.9 0.15 11.7 0.2 1.6 2 0 0 2 2 2 0 FAM176 family GntP_permease PF02447.11 EDN09243.1 - 0.15 10.5 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 GntP family permease NTPase_1 PF03266.10 EDN09243.1 - 0.18 11.4 2.3 2.9 7.5 0.0 2.9 3 0 0 3 3 3 0 NTPase CcmD PF04995.9 EDN09243.1 - 0.28 10.9 4.2 0.78 9.5 2.9 1.8 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) TSA PF03249.8 EDN09243.1 - 2 6.8 5.0 3 6.2 3.5 1.1 1 0 0 1 1 1 0 Type specific antigen SPAN PF02510.9 EDN09243.1 - 2.6 7.0 5.8 1.8 7.5 2.6 1.7 2 0 0 2 2 2 0 Surface presentation of antigens protein DUF1129 PF06570.6 EDN09244.1 - 0.00083 18.7 0.4 0.0028 16.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1129) Tetraspannin PF00335.15 EDN09244.1 - 0.0015 17.8 5.3 0.0022 17.2 3.6 1.3 1 0 0 1 1 1 1 Tetraspanin family MARVEL PF01284.18 EDN09244.1 - 0.0043 16.8 7.3 0.0044 16.8 4.4 1.5 1 1 0 1 1 1 1 Membrane-associating domain Epiglycanin_C PF14654.1 EDN09244.1 - 0.039 13.9 0.1 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region DUF3609 PF12259.3 EDN09244.1 - 0.081 11.5 0.6 0.12 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3609) DUF997 PF06196.7 EDN09244.1 - 0.27 10.7 5.9 4 7.0 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Cnd2 PF05786.9 EDN09245.1 - 1e-235 784.7 0.0 2.8e-233 776.6 0.0 2.0 1 1 0 1 1 1 1 Condensin complex subunit 2 Glyco_tranf_2_3 PF13641.1 EDN09246.1 - 3.7e-24 85.7 0.0 4.5e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EDN09246.1 - 1.1e-08 34.5 0.0 4.3e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EDN09246.1 - 1.6e-07 31.1 0.0 3.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF1904 PF08921.6 EDN09246.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) DUF3206 PF11472.3 EDN09246.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) zf-C2H2_4 PF13894.1 EDN09247.1 - 0.092 13.1 20.5 0.75 10.2 2.2 5.0 4 0 0 4 4 4 0 C2H2-type zinc finger Na_Ca_ex PF01699.19 EDN09248.1 - 4.7e-44 149.3 46.8 8.2e-24 83.7 9.9 4.0 4 0 0 4 4 4 2 Sodium/calcium exchanger protein Herpes_gE PF02480.11 EDN09248.1 - 0.055 11.7 0.1 0.17 10.1 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Vpu PF00558.14 EDN09248.1 - 0.093 12.3 0.0 0.36 10.4 0.0 2.0 1 0 0 1 1 1 0 Vpu protein EF-hand_4 PF12763.2 EDN09249.1 - 1.4e-25 88.9 0.0 1.6e-13 50.2 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 EDN09249.1 - 3.6e-10 39.1 1.1 7.5e-10 38.0 0.7 1.6 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.6 EDN09249.1 - 4.8e-07 29.7 55.3 7.3e-05 22.7 10.7 8.1 6 2 3 9 9 9 4 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 EDN09249.1 - 2.9e-05 24.1 0.8 0.0042 17.1 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EDN09249.1 - 0.0044 16.2 0.0 0.42 10.0 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EDN09249.1 - 0.098 12.2 0.0 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair RNA_pol_L_2 PF13656.1 EDN09250.1 - 5.1e-22 77.1 0.0 7.3e-22 76.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EDN09250.1 - 3.5e-12 45.2 0.0 5.3e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CorA PF01544.13 EDN09250.1 - 0.065 12.2 0.0 0.08 11.9 0.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein LRR_6 PF13516.1 EDN09253.1 - 0.028 14.4 21.2 13 6.2 0.0 8.2 9 0 0 9 9 9 0 Leucine Rich repeat LRR_4 PF12799.2 EDN09253.1 - 3.6 7.3 12.0 7.8 6.2 1.7 4.7 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) SNF2_N PF00176.18 EDN09254.1 - 1.5e-49 168.4 1.0 2.7e-48 164.3 0.7 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN09254.1 - 1.4e-12 47.2 0.0 3.6e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EDN09254.1 - 9.7e-07 28.3 6.4 2.1e-06 27.3 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN09254.1 - 6.2e-06 26.1 7.4 1.5e-05 24.8 5.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN09254.1 - 8.6e-05 22.2 7.7 0.00017 21.3 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDN09254.1 - 0.00035 20.1 6.5 0.00035 20.1 4.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN09254.1 - 0.01 15.5 7.2 0.01 15.5 5.0 1.8 2 0 0 2 2 2 1 zinc-RING finger domain ResIII PF04851.10 EDN09254.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.1 EDN09254.1 - 0.067 12.9 4.1 0.051 13.3 1.3 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 EDN09254.1 - 0.11 12.2 3.1 0.26 11.1 2.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EDN09254.1 - 5.4 6.9 13.8 0.09 12.6 4.7 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Sec2p PF06428.6 EDN09256.1 - 3.6e-10 39.5 12.8 7.8e-10 38.5 8.9 1.5 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p ATG16 PF08614.6 EDN09256.1 - 0.0019 18.0 14.7 0.0065 16.3 10.2 1.8 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) PAT1 PF09770.4 EDN09256.1 - 0.0064 14.7 18.1 0.0079 14.4 12.6 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Cluap1 PF10234.4 EDN09256.1 - 0.14 11.3 7.9 0.24 10.5 5.5 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 Latarcin PF10279.4 EDN09256.1 - 1.4 9.1 6.3 2.7 8.2 4.4 1.5 1 0 0 1 1 1 0 Latarcin precursor HAUS6_N PF14661.1 EDN09256.1 - 1.9 7.7 11.3 0.21 10.9 4.7 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus TFIIA PF03153.8 EDN09256.1 - 2.2 8.1 15.8 2.6 7.8 11.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IncA PF04156.9 EDN09256.1 - 2.4 7.7 16.5 0.09 12.3 7.0 1.7 2 0 0 2 2 2 0 IncA protein DUF605 PF04652.11 EDN09256.1 - 3 7.1 22.5 4.1 6.7 15.6 1.1 1 0 0 1 1 1 0 Vta1 like Jnk-SapK_ap_N PF09744.4 EDN09256.1 - 3.6 7.5 12.3 5.3 7.0 7.0 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.5 EDN09256.1 - 3.8 7.6 6.6 3.7 7.6 2.1 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 EDN09256.1 - 4.6 4.9 4.7 7.6 4.2 3.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EDN09256.1 - 5.6 5.8 15.1 1.4 7.7 7.9 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Lebercilin PF15619.1 EDN09256.1 - 8.5 5.7 20.7 2.4 7.5 10.4 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Heme_oxygenase PF01126.15 EDN09257.1 - 7.5e-06 25.6 0.0 0.0003 20.4 0.0 2.4 1 1 0 1 1 1 1 Heme oxygenase Ribosomal_L32e PF01655.13 EDN09258.1 - 4e-48 162.0 0.7 5.4e-48 161.6 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L32 RE_R_Pab1 PF09522.5 EDN09258.1 - 0.061 13.2 0.0 4.2 7.3 0.0 2.2 2 0 0 2 2 2 0 R.Pab1 restriction endonuclease Sugar_tr PF00083.19 EDN09259.1 - 5.9e-82 275.6 19.5 7e-82 275.3 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN09259.1 - 3.3e-25 88.5 27.9 5.3e-17 61.5 2.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TraG_N PF07916.6 EDN09260.1 - 0.13 10.6 3.6 0.17 10.2 2.5 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF2229 PF09989.4 EDN09260.1 - 1.4 8.3 7.5 2.3 7.5 5.2 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) PLRV_ORF5 PF01690.12 EDN09260.1 - 3.2 6.7 9.0 3.5 6.6 6.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein AIF_C PF14721.1 EDN09260.1 - 6.6 6.9 13.8 0.16 12.2 0.4 2.3 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DDE_1 PF03184.14 EDN09261.1 - 3.1e-30 104.9 0.0 5.3e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN09261.1 - 1e-05 25.2 0.0 2.7e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN09261.1 - 0.0016 17.9 0.6 0.0035 16.8 0.4 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain PseudoU_synth_2 PF00849.17 EDN09262.1 - 1.3e-25 90.1 0.0 2.5e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EDN09262.1 - 0.0018 17.6 0.1 0.0042 16.5 0.1 1.6 1 0 0 1 1 1 1 S4 domain DUF2757 PF10955.3 EDN09262.1 - 0.022 14.9 0.4 3.7 7.8 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2757) GFA PF04828.9 EDN09262.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme 4HBT PF03061.17 EDN09263.1 - 1.4e-07 31.5 0.0 2.7e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EDN09263.1 - 0.00028 19.9 0.1 0.00046 19.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.1 EDN09263.1 - 0.0019 18.6 0.0 0.0026 18.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily CTDII PF01556.13 EDN09264.1 - 1.9e-23 82.1 0.0 2.5e-18 65.7 0.0 2.3 2 0 0 2 2 2 2 DnaJ C terminal domain tRNA-synt_1c PF00749.16 EDN09265.1 - 1.8e-47 161.5 0.0 2.5e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain MAP65_ASE1 PF03999.7 EDN09266.1 - 2.9e-65 221.0 26.5 2.9e-65 221.0 18.4 2.6 2 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) JAB PF01398.16 EDN09267.1 - 7.9e-28 96.4 0.0 1.5e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EDN09267.1 - 2.7e-06 26.8 0.0 5.9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain FAD_binding_4 PF01565.18 EDN09269.1 - 2.1e-18 66.1 0.1 2.1e-18 66.1 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Fungal_trans PF04082.13 EDN09270.1 - 1.4e-19 69.9 1.8 2.6e-19 69.1 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EDN09270.1 - 0.0011 19.1 5.2 0.0056 16.9 3.6 2.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN09270.1 - 0.0066 16.7 5.0 0.032 14.5 3.5 2.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDN09270.1 - 0.036 14.3 1.5 0.16 12.3 1.0 2.2 1 0 0 1 1 1 0 Zinc-finger double domain RVT_1 PF00078.22 EDN09271.1 - 3.9e-26 91.7 0.0 8.1e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EDN09271.1 - 5.6e-16 57.9 0.8 1.4e-15 56.7 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EDN09271.1 - 3.2e-14 53.0 0.0 8.1e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EDN09271.1 - 0.0023 17.2 0.0 0.009 15.4 0.0 2.0 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger gag-asp_proteas PF13975.1 EDN09271.1 - 0.013 15.2 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDN09271.1 - 0.058 13.8 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.15 EDN09271.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease RasGEF PF00617.14 EDN09273.1 - 8.7e-63 211.4 0.6 3.8e-62 209.3 0.2 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EDN09273.1 - 5.1e-28 97.2 0.5 1.2e-27 96.0 0.4 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EDN09273.1 - 7.5e-15 54.0 0.1 1.5e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDN09273.1 - 1.5e-12 46.9 0.0 5.1e-12 45.1 0.1 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EDN09273.1 - 7.4e-11 41.3 0.0 2.1e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EDN09273.1 - 0.0017 18.1 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 WW domain PFL PF02901.10 EDN09274.1 - 0.0029 16.1 1.6 0.0029 16.1 1.1 1.5 1 1 1 2 2 2 1 Pyruvate formate lyase GCR1_C PF12550.3 EDN09274.1 - 0.16 11.8 0.9 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Latarcin PF10279.4 EDN09274.1 - 0.73 10.0 4.1 1.8 8.7 2.8 1.9 1 1 0 1 1 1 0 Latarcin precursor UPRTase PF14681.1 EDN09276.1 - 7.2e-75 250.7 0.0 9.3e-75 250.3 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EDN09276.1 - 3.5e-07 29.9 0.1 9.1e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.1 EDN09276.1 - 0.082 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain CRCB PF02537.10 EDN09277.1 - 8.5e-30 103.0 22.1 2.1e-18 66.2 4.3 4.0 4 1 0 4 4 4 3 CrcB-like protein RNA_pol_Rpc4 PF05132.9 EDN09279.1 - 1.4e-06 28.2 0.3 0.0002 21.3 0.0 4.1 5 0 0 5 5 5 2 RNA polymerase III RPC4 Zn_clus PF00172.13 EDN09281.1 - 0.0008 19.2 12.8 0.0019 18.0 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 EDN09281.1 - 0.011 14.9 0.0 0.037 13.2 0.0 1.9 1 0 0 1 1 1 0 Histone chaperone domain CHZ Cyclin_N PF00134.18 EDN09282.1 - 4e-43 145.9 0.5 7.3e-43 145.1 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDN09282.1 - 6.6e-33 113.1 0.0 1.3e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain HA2 PF04408.18 EDN09283.1 - 6.3e-21 74.3 0.0 1.7e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EDN09283.1 - 5.3e-18 64.9 0.0 2.1e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EDN09283.1 - 4.1e-11 42.5 0.0 2.4e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RWD PF05773.17 EDN09283.1 - 5.2e-11 42.4 0.3 1e-10 41.4 0.2 1.6 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 EDN09283.1 - 1.6e-09 37.4 0.3 2.9e-09 36.6 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EDN09283.1 - 1.6e-05 23.9 0.0 3.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EDN09283.1 - 0.00019 21.5 0.1 0.00065 19.8 0.1 1.9 1 0 0 1 1 1 1 AAA domain CoA_trans PF01144.18 EDN09283.1 - 0.0017 17.5 0.0 0.0039 16.3 0.0 1.5 1 0 0 1 1 1 1 Coenzyme A transferase UBA PF00627.26 EDN09283.1 - 0.0023 17.6 0.0 0.25 11.2 0.0 2.7 2 0 0 2 2 2 1 UBA/TS-N domain DND1_DSRM PF14709.1 EDN09283.1 - 0.003 17.7 1.5 0.017 15.3 1.1 2.3 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_29 PF13555.1 EDN09283.1 - 0.0084 15.6 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 EDN09283.1 - 0.0089 15.1 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 KaiC Zot PF05707.7 EDN09283.1 - 0.019 14.4 0.0 0.062 12.7 0.0 1.8 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_19 PF13245.1 EDN09283.1 - 0.04 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 EDN09283.1 - 0.062 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein FtsK_SpoIIIE PF01580.13 EDN09283.1 - 0.072 12.5 0.0 0.35 10.3 0.0 2.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family ResIII PF04851.10 EDN09283.1 - 0.077 12.8 0.2 0.57 9.9 0.0 2.4 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit Rap1_C PF11626.3 EDN09283.1 - 0.083 12.7 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain AAA_23 PF13476.1 EDN09283.1 - 0.099 12.9 1.8 0.11 12.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain Podovirus_Gp16 PF05894.7 EDN09283.1 - 0.33 10.2 0.0 0.54 9.5 0.0 1.3 1 0 0 1 1 1 0 Podovirus DNA encapsidation protein (Gp16) DcpS_C PF11969.3 EDN09284.1 - 8.8e-18 64.6 1.6 3e-17 62.8 1.1 1.8 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EDN09284.1 - 3.3e-16 59.5 0.1 8.7e-16 58.2 0.1 1.7 1 1 0 1 1 1 1 HIT domain SIP1 PF04938.7 EDN09284.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) TRAP_alpha PF03896.11 EDN09285.1 - 6.5e-09 35.1 0.3 2.5e-08 33.2 0.2 1.8 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit zf-CCCH_2 PF14608.1 EDN09286.1 - 0.0086 16.0 0.8 0.0086 16.0 0.6 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type bZIP_C PF12498.3 EDN09286.1 - 4.3 8.6 8.3 1.3 10.2 2.9 2.2 2 0 0 2 2 2 0 Basic leucine-zipper C terminal POT1 PF02765.12 EDN09287.1 - 7.4e-20 71.3 0.0 1.6e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Arm PF00514.18 EDN09288.1 - 2.3e-92 300.0 10.9 1.1e-13 50.4 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EDN09288.1 - 4.4e-24 84.5 0.2 3.1e-09 36.9 0.0 5.6 1 1 5 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 EDN09288.1 - 1.5e-21 76.2 5.7 5.9e-09 36.1 0.0 5.9 4 1 3 7 7 7 3 HEAT-like repeat IBB PF01749.15 EDN09288.1 - 4.7e-21 74.7 3.4 9.9e-21 73.7 2.4 1.6 1 1 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EDN09288.1 - 3.9e-20 70.0 0.0 7.5e-06 25.6 0.0 6.7 6 0 0 6 6 6 4 HEAT repeat Arm_2 PF04826.8 EDN09288.1 - 2.5e-11 43.1 0.0 0.00015 21.0 0.0 4.0 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 EDN09288.1 - 0.00017 20.0 0.0 0.062 11.6 0.0 2.7 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 EDN09288.1 - 0.00034 20.5 0.0 2 8.3 0.0 4.4 3 2 2 5 5 5 1 V-ATPase subunit H RICTOR_V PF14668.1 EDN09288.1 - 0.0019 18.1 1.5 2.3 8.1 0.0 4.5 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 EDN09288.1 - 0.0033 15.7 0.0 0.16 10.2 0.0 2.8 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EDN09288.1 - 0.009 16.3 5.7 0.87 10.2 0.1 4.9 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.4 EDN09288.1 - 0.014 15.1 0.0 13 5.5 0.0 3.6 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Glycos_trans_3N PF02885.12 EDN09288.1 - 0.099 12.2 0.0 70 3.1 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain SURF6 PF04935.7 EDN09288.1 - 3.1 7.0 10.5 4.5 6.4 7.3 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 Amidase PF01425.16 EDN09289.1 - 7.9e-100 334.7 0.0 9.3e-100 334.5 0.0 1.0 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 EDN09291.1 - 1.4e-33 116.0 24.8 1.4e-33 116.0 17.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.20 EDN09292.1 - 0.0014 17.7 0.0 0.0014 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Yae1_N PF09811.4 EDN09293.1 - 2.8e-12 45.9 0.4 5.5e-12 45.0 0.3 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Pex14_N PF04695.8 EDN09293.1 - 3.4 7.6 5.9 6.4 6.8 4.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2450 PF10475.4 EDN09294.1 - 0.43 9.4 1.8 0.67 8.7 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) SCO1-SenC PF02630.9 EDN09295.1 - 1.3e-61 207.2 0.1 1.7e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EDN09295.1 - 0.00029 20.5 0.1 0.00058 19.5 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EDN09295.1 - 0.00066 19.7 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like HNH PF01844.18 EDN09295.1 - 0.033 14.0 0.0 4.3 7.2 0.0 2.5 2 0 0 2 2 2 0 HNH endonuclease Redoxin PF08534.5 EDN09295.1 - 0.061 12.8 0.1 0.43 10.1 0.0 2.2 2 1 0 2 2 2 0 Redoxin Aldo_ket_red PF00248.16 EDN09296.1 - 1.1e-60 204.8 0.0 1.3e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family G-patch PF01585.18 EDN09297.1 - 1.1e-09 37.8 2.3 2.5e-09 36.7 1.6 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EDN09297.1 - 6.5e-07 29.1 0.6 6.5e-07 29.1 0.4 1.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_1 PF00076.17 EDN09297.1 - 3.6e-05 23.3 0.0 0.00011 21.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 EDN09297.1 - 0.00026 20.2 3.9 0.00049 19.3 2.7 1.4 1 0 0 1 1 1 1 RED-like protein N-terminal region RRM_6 PF14259.1 EDN09297.1 - 0.00075 19.4 0.0 0.0021 17.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN09297.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad50_zn_hook PF04423.9 EDN09297.1 - 0.065 12.7 3.8 0.11 11.9 0.3 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif DIT1_PvcA PF05141.7 EDN09297.1 - 0.27 10.5 2.0 0.44 9.8 1.4 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein RTA1 PF04479.8 EDN09300.1 - 7.7e-42 143.2 2.4 1.3e-41 142.5 1.6 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF2567 PF10821.3 EDN09300.1 - 0.01 15.3 0.4 0.95 8.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) zf-DHHC PF01529.15 EDN09300.1 - 2.4 7.5 4.6 13 5.1 0.2 2.5 2 1 0 2 2 2 0 DHHC palmitoyltransferase DUF3433 PF11915.3 EDN09301.1 - 5.4e-35 119.4 17.5 1.2e-28 99.1 1.1 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) AAA_10 PF12846.2 EDN09303.1 - 1.6e-11 44.2 0.1 2.6e-10 40.2 0.1 2.1 1 1 0 1 1 1 1 AAA-like domain Zot PF05707.7 EDN09303.1 - 0.00055 19.4 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA PF00004.24 EDN09303.1 - 0.0033 17.6 0.1 0.01 16.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN09303.1 - 0.0083 16.2 0.0 3.5 7.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Aldolase_2 PF10120.4 EDN09303.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative aldolase FtsK_SpoIIIE PF01580.13 EDN09303.1 - 0.021 14.2 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.10 EDN09303.1 - 0.069 11.7 0.0 0.13 10.8 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein Zeta_toxin PF06414.7 EDN09303.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin SUR7 PF06687.7 EDN09304.1 - 3.7e-29 101.8 9.3 4.7e-29 101.4 6.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family NfeD PF01957.13 EDN09304.1 - 0.45 10.6 3.9 0.21 11.7 0.3 2.0 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding RTA1 PF04479.8 EDN09305.1 - 4e-17 62.4 1.9 6.1e-17 61.8 1.3 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF308 PF03729.8 EDN09305.1 - 0.0093 15.9 0.9 0.0093 15.9 0.6 3.0 3 1 1 4 4 4 1 Short repeat of unknown function (DUF308) PQ-loop PF04193.9 EDN09305.1 - 0.038 13.5 0.1 0.13 11.8 0.0 2.0 1 0 0 1 1 1 0 PQ loop repeat SNARE PF05739.14 EDN09306.1 - 1.4e-17 63.1 1.2 4e-17 61.6 0.1 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EDN09306.1 - 3.3e-14 52.8 0.1 3.3e-14 52.8 0.1 2.7 3 1 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 EDN09306.1 - 0.0059 16.1 0.9 0.0059 16.1 0.6 2.0 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Sed5p PF11416.3 EDN09306.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 Integral membrane protein Sed5p NPV_P10 PF05531.7 EDN09306.1 - 0.064 13.5 1.7 23 5.3 0.1 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin-18_N PF10496.4 EDN09306.1 - 1.3 8.8 6.2 3.2 7.6 0.3 3.4 3 1 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus HTH_29 PF13551.1 EDN09309.1 - 0.081 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix Cupin_5 PF06172.6 EDN09310.1 - 2.7e-35 121.3 0.0 3.2e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) RRM_1 PF00076.17 EDN09311.1 - 6e-14 51.4 0.0 1.1e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN09311.1 - 2.5e-12 46.5 0.0 4.3e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN09311.1 - 7.4e-07 28.9 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 EDN09311.1 - 0.1 12.1 5.5 0.19 11.3 3.8 1.3 1 0 0 1 1 1 0 IncA protein NARP1 PF12569.3 EDN09311.1 - 1.6 7.3 13.2 2.4 6.8 9.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Hex_IIIa PF02455.11 EDN09311.1 - 9 4.8 8.6 14 4.2 6.0 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Apt1 PF10351.4 EDN09314.1 - 1.3e-169 564.9 2.8 3.3e-169 563.5 2.0 1.8 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EDN09314.1 - 2.2e-158 527.6 0.8 3.8e-158 526.8 0.0 1.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27 PF10344.4 EDN09314.1 - 5.2e-156 520.7 0.0 3.4e-108 362.5 0.1 2.3 1 1 1 2 2 2 2 Mitochondrial protein from FMP27 DUF2405 PF10293.4 EDN09314.1 - 1.5e-57 193.7 0.2 3.5e-57 192.5 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 EDN09314.1 - 3.6e-46 156.9 0.0 9.3e-46 155.5 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 EDN09314.1 - 5.7e-35 119.8 0.0 2.7e-34 117.7 0.0 2.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain B-block_TFIIIC PF04182.7 EDN09316.1 - 1e-20 73.3 0.0 2.6e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC DUF3361 PF11841.3 EDN09316.1 - 0.1 12.3 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) Rhomboid PF01694.17 EDN09319.1 - 1.2e-36 125.9 11.3 1.2e-36 125.9 7.8 2.4 3 0 0 3 3 3 1 Rhomboid family DUF4107 PF13389.1 EDN09319.1 - 0.23 11.1 0.5 0.5 10.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) DUF1212 PF06738.7 EDN09319.1 - 1.1 8.6 4.4 59 3.0 4.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) PAT1 PF09770.4 EDN09319.1 - 7.1 4.7 14.9 9.5 4.3 10.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 VKOR PF07884.9 EDN09319.1 - 9.2 6.1 10.8 0.1 12.4 1.4 2.1 2 0 0 2 2 2 0 Vitamin K epoxide reductase family DUF3317 PF11779.3 EDN09320.1 - 2.7e-20 71.5 3.8 3.7e-20 71.0 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) SecE PF00584.15 EDN09320.1 - 0.12 11.9 0.5 0.2 11.2 0.3 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Kinetochor_Ybp2 PF08568.5 EDN09321.1 - 6.1e-151 503.7 0.1 1.6e-117 393.4 0.3 2.1 1 1 1 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Pentapeptide_4 PF13599.1 EDN09322.1 - 2.8e-08 33.4 0.0 5e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EDN09322.1 - 0.0066 16.3 0.1 7.6 6.5 0.0 3.1 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) CfAFP PF05264.6 EDN09322.1 - 1.4 8.7 12.4 0.22 11.2 0.7 2.7 1 1 1 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) PLDc_2 PF13091.1 EDN09324.1 - 2.8e-14 52.9 0.0 4.6e-06 26.3 0.0 3.2 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EDN09324.1 - 1.2e-11 43.9 1.1 3.8e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF4188 PF13826.1 EDN09326.1 - 6.8e-36 122.9 0.2 1.6e-35 121.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 EDN09326.1 - 0.0019 17.2 0.2 0.0042 16.1 0.1 1.5 1 1 0 1 1 1 1 Haem-containing dehydratase DUF2062 PF09835.4 EDN09326.1 - 0.054 13.0 2.4 0.088 12.4 1.2 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) Cyanate_lyase PF02560.9 EDN09327.1 - 4.2e-32 109.4 0.0 8e-32 108.6 0.0 1.5 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.17 EDN09327.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix zf-C2H2 PF00096.21 EDN09328.1 - 7e-09 35.5 35.3 0.0098 16.1 0.6 6.4 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN09328.1 - 3.2e-07 30.1 26.5 0.043 14.1 0.3 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDN09328.1 - 5.1e-06 26.2 23.7 0.094 12.6 0.2 5.9 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDN09328.1 - 1.8e-05 24.7 27.0 0.00042 20.3 0.2 6.1 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDN09328.1 - 0.00048 20.2 25.7 0.028 14.6 0.1 6.2 6 0 0 6 6 6 2 Zinc-finger of C2H2 type Rad50_zn_hook PF04423.9 EDN09328.1 - 0.00088 18.6 1.2 0.00088 18.6 0.8 3.3 4 0 0 4 4 4 1 Rad50 zinc hook motif DUF629 PF04780.7 EDN09328.1 - 0.002 16.7 1.6 0.002 16.7 1.1 3.8 2 2 2 4 4 4 2 Protein of unknown function (DUF629) zf-C2HC_2 PF13913.1 EDN09328.1 - 0.0069 16.0 12.8 2.1 8.1 0.1 4.2 4 0 0 4 4 4 3 zinc-finger of a C2HC-type DNA_pol_B PF00136.16 EDN09331.1 - 1.2e-146 489.1 4.7 2e-146 488.4 3.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EDN09331.1 - 1.9e-70 237.3 0.0 4.7e-70 236.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EDN09331.1 - 2.3e-24 85.2 4.2 4.7e-24 84.1 2.9 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta C1_1 PF00130.17 EDN09331.1 - 0.21 11.3 10.3 0.046 13.4 0.9 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Tyrosinase PF00264.15 EDN09332.1 - 1.3e-43 149.7 1.2 2e-43 149.1 0.8 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Pkinase PF00069.20 EDN09336.1 - 5.6e-34 117.4 0.0 4.7e-21 75.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN09336.1 - 4.4e-13 48.8 0.0 1.5e-05 24.2 0.0 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase DCR PF14047.1 EDN09336.1 - 0.015 15.5 0.0 0.035 14.3 0.0 1.5 1 0 0 1 1 1 0 Dppa2/4 conserved region Kinase-like PF14531.1 EDN09336.1 - 0.063 12.2 0.0 0.93 8.3 0.0 2.4 3 0 0 3 3 3 0 Kinase-like 3-dmu-9_3-mt PF06983.8 EDN09337.1 - 6.9e-36 123.0 0.5 5.8e-35 120.1 0.4 2.0 1 1 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Glyco_hydro_47 PF01532.15 EDN09338.1 - 3.3e-165 550.1 0.0 4.1e-165 549.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Syja_N PF02383.13 EDN09339.1 - 2.7e-68 230.1 0.1 2.9e-43 147.8 0.0 2.5 1 1 1 2 2 2 2 SacI homology domain DUF2454 PF10521.4 EDN09340.1 - 3.8e-98 327.9 4.4 4.7e-98 327.6 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 EDN09341.1 - 7.6e-25 87.5 0.6 4.5e-24 85.0 0.4 2.3 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EDN09341.1 - 5e-07 29.2 0.0 1.2e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EDN09341.1 - 0.00098 18.9 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative TRAPPC-Trs85 PF12739.2 EDN09342.1 - 3e-121 404.9 0.2 1.7e-120 402.5 0.1 1.9 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Snf7 PF03357.16 EDN09343.1 - 2.9e-19 69.0 10.9 2.9e-19 69.0 7.6 1.6 1 1 0 1 1 1 1 Snf7 Nuc_N PF14448.1 EDN09343.1 - 0.032 13.7 0.1 2 8.0 0.0 2.7 2 0 0 2 2 2 0 Nuclease N terminal BLOC1_2 PF10046.4 EDN09343.1 - 0.21 11.7 14.5 6 7.0 0.1 4.3 5 0 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 EDN09343.1 - 6.8 6.6 9.3 7.6 6.4 0.4 3.1 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) zf-RING_6 PF14835.1 EDN09344.1 - 1.5e-09 37.4 4.8 3.1e-09 36.4 3.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 EDN09344.1 - 2.6e-08 33.7 14.1 2.6e-08 33.7 9.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN09344.1 - 3.6e-07 29.7 13.1 3.6e-07 29.7 9.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDN09344.1 - 5.1e-07 29.2 12.6 5.1e-07 29.2 8.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN09344.1 - 5.4e-07 29.1 10.8 5.4e-07 29.1 7.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 EDN09344.1 - 1.6e-06 27.4 0.1 3.4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-RING_2 PF13639.1 EDN09344.1 - 2.7e-06 27.1 12.8 2.7e-06 27.1 8.9 2.3 2 0 0 2 2 2 1 Ring finger domain U-box PF04564.10 EDN09344.1 - 8.5e-06 25.6 0.0 3.6e-05 23.6 0.0 2.1 2 0 0 2 2 1 1 U-box domain zf-C3HC4_4 PF15227.1 EDN09344.1 - 5.8e-05 22.8 15.7 6.3e-05 22.7 8.7 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EDN09344.1 - 0.00082 18.9 5.0 0.00082 18.9 3.5 2.8 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain Mob_synth_C PF06463.8 EDN09344.1 - 0.0011 18.7 4.1 0.0011 18.7 2.8 1.7 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C zf-RING_UBOX PF13445.1 EDN09344.1 - 0.0044 16.6 9.4 0.0044 16.6 6.5 2.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.2 EDN09344.1 - 0.0057 16.7 5.5 0.0057 16.7 3.8 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EDN09344.1 - 0.052 13.3 5.4 0.051 13.4 1.4 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sgf11 PF08209.6 EDN09344.1 - 0.056 12.7 0.1 0.056 12.7 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Rad50_zn_hook PF04423.9 EDN09344.1 - 0.92 9.0 6.8 5.2 6.6 0.0 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif CDC27 PF09507.5 EDN09345.1 - 4.9e-123 411.5 20.2 5.5e-123 411.3 14.0 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF1237 PF06824.6 EDN09346.1 - 1.7e-179 596.8 0.0 2e-179 596.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) NMD3 PF04981.8 EDN09347.1 - 1.1e-76 257.1 7.4 1.5e-76 256.6 5.1 1.2 1 0 0 1 1 1 1 NMD3 family FYVE_2 PF02318.11 EDN09347.1 - 2 8.3 8.3 3 7.7 2.4 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger HypA PF01155.14 EDN09347.1 - 3.9 7.1 11.0 4.5 6.9 1.2 3.1 3 1 1 4 4 4 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EDN09347.1 - 5.9 6.8 14.4 5 7.0 0.1 2.8 2 1 0 2 2 2 0 Double zinc ribbon Pex2_Pex12 PF04757.9 EDN09349.1 - 5.6e-57 192.7 2.6 7.1e-57 192.4 1.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EDN09349.1 - 4.8e-07 29.5 2.7 8e-07 28.8 1.9 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EDN09349.1 - 6.2e-07 29.3 3.0 1e-06 28.6 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN09349.1 - 3.4e-05 23.5 1.4 5.6e-05 22.8 1.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDN09349.1 - 0.0011 18.6 1.6 0.0018 17.8 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN09349.1 - 0.0069 16.0 0.9 0.011 15.4 0.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Alpha_GJ PF03229.8 EDN09349.1 - 0.41 11.0 6.9 0.93 9.8 4.8 1.6 1 0 0 1 1 1 0 Alphavirus glycoprotein J Mito_carr PF00153.22 EDN09350.1 - 7.6e-28 96.0 0.5 2.3e-18 65.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DDT PF02791.12 EDN09351.1 - 3.8e-20 71.4 2.7 7.6e-20 70.4 1.9 1.5 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EDN09351.1 - 6.3e-13 48.0 0.3 1.4e-12 46.9 0.2 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WAC_Acf1_DNA_bd PF10537.4 EDN09351.1 - 3.6e-09 36.7 0.0 1.8e-08 34.4 0.0 2.3 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WHIM3 PF15614.1 EDN09351.1 - 6.5e-05 22.6 0.2 0.0002 21.0 0.1 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 EDN09351.1 - 0.00011 21.8 0.2 0.00042 20.1 0.1 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Alg6_Alg8 PF03155.10 EDN09352.1 - 2.1e-132 442.2 25.1 2.7e-132 441.9 17.4 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.8 EDN09353.1 - 3.5e-20 72.1 0.0 1.4e-18 66.8 0.0 2.1 1 1 1 2 2 2 1 Legume-like lectin family DUF869 PF05911.6 EDN09353.1 - 0.0045 15.3 0.4 0.0059 14.9 0.3 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) GspL_C PF12693.2 EDN09353.1 - 0.0074 16.0 5.4 0.0094 15.7 2.8 1.9 1 1 1 2 2 2 1 GspL periplasmic domain ApoLp-III PF07464.6 EDN09353.1 - 0.018 15.0 3.0 1.4 8.9 0.6 2.1 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.7 EDN09353.1 - 0.023 14.5 9.6 0.13 12.1 2.3 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lyase_8_N PF08124.6 EDN09353.1 - 0.065 12.0 0.6 0.094 11.5 0.4 1.2 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain ISG65-75 PF11727.3 EDN09353.1 - 0.1 11.6 0.8 0.16 11.0 0.6 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein FlaC_arch PF05377.6 EDN09353.1 - 0.11 12.4 1.0 8.2 6.4 0.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FUSC PF04632.7 EDN09353.1 - 0.27 9.6 0.7 0.37 9.1 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3584 PF12128.3 EDN09353.1 - 0.28 8.4 7.2 0.35 8.1 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PilJ PF13675.1 EDN09353.1 - 0.33 11.2 5.1 0.65 10.3 1.0 2.1 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DASH_Dad2 PF08654.5 EDN09353.1 - 0.34 10.9 6.0 0.64 10.0 1.3 2.8 1 1 2 3 3 3 0 DASH complex subunit Dad2 OmpH PF03938.9 EDN09353.1 - 0.42 10.5 5.1 0.69 9.8 3.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FliT PF05400.8 EDN09353.1 - 0.86 10.0 8.5 0.56 10.6 4.6 1.6 1 1 0 1 1 1 0 Flagellar protein FliT TMCO5 PF14992.1 EDN09353.1 - 0.95 8.5 4.8 0.63 9.1 2.4 1.3 1 1 0 1 1 1 0 TMCO5 family PspB PF06667.7 EDN09353.1 - 1.5 8.8 6.9 1.2 9.1 1.5 2.8 2 1 1 3 3 3 0 Phage shock protein B Fib_alpha PF08702.5 EDN09353.1 - 4.6 7.3 7.3 7.3 6.6 4.8 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Syntaxin PF00804.20 EDN09353.1 - 9.7 6.4 10.3 9.5 6.4 5.1 2.3 1 1 1 2 2 2 0 Syntaxin PHD PF00628.24 EDN09354.1 - 2.9e-17 62.0 17.5 4e-12 45.6 4.9 2.5 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.1 EDN09354.1 - 0.0043 16.3 5.5 0.44 9.8 0.8 2.5 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EDN09354.1 - 0.4 10.4 8.9 3.5 7.4 0.9 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1880 PF08976.6 EDN09354.1 - 1.5 8.9 6.8 0.49 10.5 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) Prok-RING_1 PF14446.1 EDN09354.1 - 3.5 7.4 12.4 0.2 11.4 1.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EDN09354.1 - 7.9 5.8 11.8 7.4 5.9 0.8 3.2 3 0 0 3 3 3 0 PHD-finger Peptidase_M24 PF00557.19 EDN09356.1 - 5.1e-13 49.0 0.0 7e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 BLVR PF06375.6 EDN09356.1 - 0.041 13.7 6.8 0.082 12.7 4.7 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Aldo_ket_red PF00248.16 EDN09356.1 - 0.041 12.7 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 Aldo/keto reductase family Exo_endo_phos PF03372.18 EDN09357.1 - 6.3e-12 45.9 0.2 8.4e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF5 PF04855.7 EDN09358.1 - 3.4e-79 265.7 0.3 5.9e-79 264.9 0.2 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 HEAT_2 PF13646.1 EDN09359.1 - 1.8e-09 37.7 4.6 9.9e-06 25.7 0.6 5.1 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.17 EDN09359.1 - 8.2e-06 25.4 0.6 0.049 13.7 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat CLASP_N PF12348.3 EDN09359.1 - 8.2e-05 22.0 1.0 0.64 9.3 0.0 3.6 4 0 0 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.1 EDN09359.1 - 0.00012 22.3 1.7 0.039 14.4 0.0 4.7 5 0 0 5 5 5 1 HEAT-like repeat MFS_1 PF07690.11 EDN09360.1 - 4.8e-39 134.0 39.2 5.7e-39 133.8 27.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4231 PF14015.1 EDN09360.1 - 0.037 14.0 0.9 0.037 14.0 0.6 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) DDE_Tnp_1_7 PF13843.1 EDN09363.1 - 9.6e-52 176.1 0.0 6.1e-48 163.6 0.0 3.0 1 1 1 2 2 2 2 Transposase IS4 DDE_Tnp_1_7 PF13843.1 EDN09364.1 - 6.3e-26 91.2 1.0 8.3e-20 71.1 0.9 2.3 1 1 1 2 2 2 2 Transposase IS4 zf-RING_2 PF13639.1 EDN09365.1 - 1.1e-09 37.9 1.0 1.1e-09 37.9 0.7 3.4 3 0 0 3 3 3 1 Ring finger domain PHD PF00628.24 EDN09365.1 - 1.8e-09 37.1 5.7 1.8e-09 37.1 3.9 2.6 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EDN09365.1 - 3.3e-07 29.5 3.4 8e-07 28.2 2.3 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.1 EDN09365.1 - 2.2e-06 27.2 0.3 2.2e-06 27.2 0.2 3.3 4 0 0 4 4 4 1 zinc-RING finger domain zf-rbx1 PF12678.2 EDN09365.1 - 2.2e-06 27.6 0.2 2.2e-06 27.6 0.2 3.2 4 0 0 4 4 3 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EDN09365.1 - 3.3e-06 26.6 0.6 3.3e-06 26.6 0.4 3.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN09365.1 - 6.7e-06 26.0 0.6 6.7e-06 26.0 0.4 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN09365.1 - 1.2e-05 24.8 0.4 1.2e-05 24.8 0.3 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDN09365.1 - 0.00024 20.9 0.3 0.00024 20.9 0.2 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EDN09365.1 - 0.00087 18.7 3.6 0.006 16.1 0.2 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EDN09365.1 - 0.029 13.9 0.2 0.029 13.9 0.2 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.2 EDN09365.1 - 0.22 11.3 6.4 0.19 11.5 0.8 2.9 1 1 1 2 2 2 0 Double zinc ribbon zf-RING-like PF08746.6 EDN09365.1 - 0.39 10.7 11.2 3.4 7.7 1.3 2.8 2 0 0 2 2 2 0 RING-like domain zf-RING_UBOX PF13445.1 EDN09365.1 - 0.52 10.0 6.7 0.73 9.5 0.0 3.0 3 0 0 3 3 3 0 RING-type zinc-finger zf-PHD-like PF15446.1 EDN09365.1 - 0.88 8.8 6.7 0.078 12.2 0.3 2.4 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Ribosomal_L37ae PF01780.14 EDN09367.1 - 3e-41 139.1 8.7 3.3e-41 139.0 6.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EDN09367.1 - 0.02 14.7 2.6 0.028 14.2 1.8 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.10 EDN09367.1 - 0.039 13.6 2.4 1.6 8.5 0.0 2.3 1 1 1 2 2 2 0 BED zinc finger A2L_zn_ribbon PF08792.5 EDN09367.1 - 0.41 10.1 2.4 0.5 9.8 0.1 1.9 2 0 0 2 2 2 0 A2L zinc ribbon domain Saccharop_dh PF03435.13 EDN09368.1 - 1e-14 54.3 0.1 3.5e-13 49.3 0.0 2.7 2 1 0 2 2 2 1 Saccharopine dehydrogenase Ribosomal_S16 PF00886.14 EDN09368.1 - 0.064 12.9 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S16 Pinin_SDK_memA PF04696.8 EDN09369.1 - 8.3e-30 103.0 11.8 8.3e-30 103.0 8.2 2.2 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region PHF5 PF03660.9 EDN09370.1 - 1.4e-51 173.0 10.1 1.6e-51 172.8 7.0 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EDN09370.1 - 0.8 9.5 15.0 5.3 6.9 1.5 2.8 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.1 EDN09370.1 - 1.1 9.0 15.2 3.2 7.5 0.4 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 EDN09370.1 - 4.6 4.7 5.4 4.5 4.7 3.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Cofilin_ADF PF00241.15 EDN09371.1 - 1.7e-10 40.8 0.0 7.5e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.22 EDN09372.1 - 2e-44 149.2 0.2 2.4e-22 78.4 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Phi-29_GP3 PF05435.6 EDN09372.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 DUF4137 PF13593.1 EDN09373.1 - 1.3e-20 73.7 0.1 5.4e-20 71.7 0.1 1.7 1 1 1 2 2 2 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 EDN09373.1 - 0.0041 16.5 0.1 0.0055 16.1 0.1 1.1 1 0 0 1 1 1 1 Sodium Bile acid symporter family Sec1 PF00995.18 EDN09374.1 - 0.086 11.4 1.2 0.13 10.8 0.9 1.3 1 0 0 1 1 1 0 Sec1 family CAF1 PF04857.15 EDN09375.1 - 1.1e-36 126.5 0.0 1.7e-36 125.8 0.0 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease FAM212 PF15342.1 EDN09375.1 - 0.0072 15.9 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 FAM212 family NAM-associated PF14303.1 EDN09375.1 - 0.069 13.4 0.2 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DNA_pol_A_exo1 PF01612.15 EDN09375.1 - 0.072 12.5 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 3'-5' exonuclease MRP-L46 PF11788.3 EDN09376.1 - 6.3e-35 120.1 0.5 1.1e-34 119.3 0.4 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Cript PF10235.4 EDN09377.1 - 3.3e-35 120.3 8.1 3.3e-35 120.3 5.6 1.5 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT zf-ribbon_3 PF13248.1 EDN09377.1 - 0.0016 17.5 7.9 0.03 13.5 1.4 3.3 3 0 0 3 3 3 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EDN09377.1 - 0.0089 15.4 9.7 0.24 10.9 1.1 3.4 2 1 1 3 3 3 2 zinc-ribbon domain DUF1363 PF07101.6 EDN09377.1 - 0.012 15.6 1.5 0.016 15.2 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1363) DZR PF12773.2 EDN09377.1 - 0.014 15.2 17.4 0.045 13.5 7.0 2.9 1 1 2 3 3 3 0 Double zinc ribbon eIF-4B PF06273.6 EDN09377.1 - 0.12 11.1 1.0 0.13 10.9 0.7 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B zf-AD PF07776.10 EDN09377.1 - 3.5 7.7 9.8 3.4 7.7 2.4 2.6 2 1 0 2 2 2 0 Zinc-finger associated domain (zf-AD) zf-FPG_IleRS PF06827.9 EDN09377.1 - 3.6 7.3 7.6 3.5 7.3 1.8 2.9 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS RRN7 PF11781.3 EDN09377.1 - 5.3 6.6 10.4 0.42 10.1 2.3 2.5 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Med27 PF11571.3 EDN09377.1 - 6.3 6.9 9.7 1.3 9.2 0.1 3.1 2 1 0 2 2 2 0 Mediator complex subunit 27 DUF2039 PF10217.4 EDN09377.1 - 7.9 6.5 19.5 2.5 8.1 8.9 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2039) LIN37 PF15306.1 EDN09378.1 - 0.059 13.3 2.1 0.07 13.1 1.5 1.2 1 0 0 1 1 1 0 LIN37 Ribosomal_60s PF00428.14 EDN09378.1 - 0.15 12.4 2.4 0.2 12.0 1.7 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein RVT_1 PF00078.22 EDN09379.1 - 2.7e-06 26.9 0.1 3.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1349 PF07081.6 EDN09380.1 - 4.1e-18 65.3 0.0 1.8e-07 30.7 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1349) AMP-binding PF00501.23 EDN09381.1 - 6.3e-86 288.3 0.0 9.4e-86 287.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EDN09381.1 - 2.1e-79 266.5 0.0 7e-41 140.0 0.0 4.0 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.20 EDN09381.1 - 1.7e-18 66.6 2.8 1.5e-08 34.7 0.3 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EDN09381.1 - 5.5e-05 24.0 0.2 0.00017 22.4 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Trp_DMAT PF11991.3 EDN09382.1 - 1e-108 363.8 0.0 1.2e-108 363.6 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Abhydrolase_2 PF02230.11 EDN09383.1 - 2.4e-11 43.5 0.3 5.5e-05 22.7 0.3 3.4 3 1 0 3 3 3 2 Phospholipase/Carboxylesterase RP-C_C PF11800.3 EDN09383.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF536 PF04394.9 EDN09384.1 - 0.21 11.3 0.4 0.21 11.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF536 NOC3p PF07540.6 EDN09387.1 - 5.3e-33 113.1 1.5 9.4e-33 112.3 0.0 2.2 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 EDN09387.1 - 1.9e-25 89.1 0.2 6.7e-25 87.4 0.1 2.0 1 0 0 1 1 1 1 CBF/Mak21 family UPF0113 PF03657.8 EDN09388.1 - 6.8e-09 35.5 0.0 8.2e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EDN09388.1 - 0.058 13.1 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 PUA domain Cullin_binding PF03556.10 EDN09389.1 - 6.1e-30 103.7 1.8 8.6e-30 103.2 1.2 1.1 1 0 0 1 1 1 1 Cullin binding Daxx PF03344.10 EDN09390.1 - 0.021 13.3 6.0 0.017 13.6 4.2 1.1 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 EDN09390.1 - 0.023 14.2 6.9 0.04 13.4 4.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF3381 PF11861.3 EDN09390.1 - 0.023 14.1 4.2 2.1 7.8 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) MYCBPAP PF14646.1 EDN09390.1 - 0.032 12.9 0.6 0.037 12.7 0.4 1.1 1 0 0 1 1 1 0 MYCBP-associated protein family IFT57 PF10498.4 EDN09390.1 - 0.076 11.7 1.3 0.081 11.6 0.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF3682 PF12446.3 EDN09390.1 - 0.092 13.0 7.2 0.18 12.1 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF4246 PF14033.1 EDN09390.1 - 0.15 10.6 2.2 0.16 10.5 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) BSP_II PF05432.6 EDN09390.1 - 0.2 10.8 9.4 0.28 10.4 6.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 EDN09390.1 - 0.27 10.8 3.3 0.38 10.4 2.3 1.2 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.11 EDN09390.1 - 0.32 9.9 2.1 0.38 9.7 1.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit VID27 PF08553.5 EDN09390.1 - 0.51 8.4 4.0 0.54 8.4 2.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Sigma70_ner PF04546.8 EDN09390.1 - 0.69 9.4 7.8 1.1 8.8 5.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Pox_Ag35 PF03286.9 EDN09390.1 - 0.79 9.2 5.6 0.9 9.0 3.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RXT2_N PF08595.6 EDN09390.1 - 0.81 9.4 4.7 1.2 8.9 3.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Paf1 PF03985.8 EDN09390.1 - 0.99 8.0 8.2 1.4 7.5 5.7 1.2 1 0 0 1 1 1 0 Paf1 CobT PF06213.7 EDN09390.1 - 1.2 8.1 9.9 1.6 7.8 6.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 EDN09390.1 - 1.4 6.8 3.8 1.6 6.6 2.6 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.13 EDN09390.1 - 2.4 6.4 7.4 3.5 5.9 5.1 1.2 1 0 0 1 1 1 0 Hsp90 protein Nucleo_P87 PF07267.6 EDN09390.1 - 2.6 6.6 7.8 3.4 6.2 5.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Myc_N PF01056.13 EDN09390.1 - 3 6.9 9.6 4.2 6.4 6.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region NESP55 PF06390.7 EDN09390.1 - 4.6 6.5 20.0 0.43 9.9 0.9 2.1 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Sporozoite_P67 PF05642.6 EDN09390.1 - 6.9 4.4 6.4 9.1 3.9 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SWIB PF02201.13 EDN09392.1 - 1.3e-14 53.6 0.0 2.4e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Fn_bind PF02986.9 EDN09392.1 - 0.47 10.0 4.7 1.1 8.8 3.2 1.6 1 0 0 1 1 1 0 Fibronectin binding repeat Band_7 PF01145.20 EDN09393.1 - 4.1e-28 98.4 1.7 4.1e-28 98.4 1.2 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family CagX PF03524.10 EDN09394.1 - 0.029 13.6 1.6 0.043 13.0 1.1 1.2 1 0 0 1 1 1 0 Conjugal transfer protein Peptidase_S49_N PF08496.5 EDN09394.1 - 0.042 13.6 13.4 0.068 12.9 9.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rtf2 PF04641.7 EDN09394.1 - 0.05 12.7 17.0 0.085 12.0 11.8 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger RNase_H2-Ydr279 PF09468.5 EDN09394.1 - 0.063 12.4 19.0 0.084 12.0 13.2 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SR-25 PF10500.4 EDN09394.1 - 0.065 12.6 28.6 0.13 11.7 19.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Vfa1 PF08432.5 EDN09394.1 - 0.082 12.9 18.9 0.11 12.5 13.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Neur_chan_memb PF02932.11 EDN09394.1 - 0.34 10.7 3.5 0.42 10.4 2.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Folate_carrier PF01770.13 EDN09394.1 - 0.39 9.1 2.0 0.55 8.6 1.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier Pox_Ag35 PF03286.9 EDN09394.1 - 0.54 9.7 16.2 0.85 9.1 11.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Zip PF02535.17 EDN09394.1 - 0.62 9.0 1.7 1.4 7.8 1.2 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter GAGA_bind PF06217.7 EDN09394.1 - 0.63 9.9 15.4 0.95 9.3 10.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4647 PF15504.1 EDN09394.1 - 0.94 8.2 13.6 1.2 7.9 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) HA2 PF04408.18 EDN09394.1 - 1.1 9.3 3.5 2.2 8.3 2.4 1.5 1 0 0 1 1 1 0 Helicase associated domain (HA2) DUF1168 PF06658.7 EDN09394.1 - 1.5 8.3 33.3 2.4 7.6 23.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DDHD PF02862.12 EDN09394.1 - 1.6 8.4 6.1 2.4 7.8 4.2 1.2 1 0 0 1 1 1 0 DDHD domain LicD PF04991.8 EDN09394.1 - 1.6 8.7 9.2 2.6 8.0 6.4 1.3 1 0 0 1 1 1 0 LicD family MIP-T3 PF10243.4 EDN09394.1 - 1.7 7.0 26.8 2.1 6.7 18.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 U79_P34 PF03064.11 EDN09394.1 - 1.9 7.9 22.8 2.9 7.3 15.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2149 PF09919.4 EDN09394.1 - 3.6 7.7 5.6 6 7.0 3.9 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Peroxin-13_N PF04088.8 EDN09394.1 - 5.8 6.8 5.7 9 6.2 4.0 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region fn1 PF00039.13 EDN09396.1 - 0.15 11.8 0.8 0.4 10.5 0.1 2.0 2 0 0 2 2 2 0 Fibronectin type I domain PTR2 PF00854.16 EDN09397.1 - 2e-58 197.9 6.3 6.4e-31 107.4 2.7 2.2 1 1 1 2 2 2 2 POT family Glyco_hydro_18 PF00704.23 EDN09398.1 - 1.3e-90 304.3 1.0 1.6e-90 304.0 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.18 EDN09399.1 - 1.6e-34 117.0 0.9 2.8e-34 116.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EDN09399.1 - 1.9e-28 98.0 2.0 3.8e-28 97.0 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EDN09399.1 - 5.9e-20 70.7 0.7 1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDN09399.1 - 8.7e-06 25.9 0.2 4e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDN09399.1 - 0.00012 21.7 0.1 0.0002 21.1 0.0 1.3 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EDN09399.1 - 0.0007 19.4 0.7 0.0015 18.4 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDN09399.1 - 0.0042 17.2 0.5 0.0058 16.8 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 EDN09399.1 - 0.0079 16.0 0.6 0.012 15.4 0.4 1.3 1 0 0 1 1 1 1 IBR domain DUF2870 PF11069.3 EDN09399.1 - 0.054 13.5 0.7 0.1 12.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EDN09399.1 - 0.089 11.0 2.4 2.2 6.4 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain zf-H2C2_2 PF13465.1 EDN09400.1 - 1.1e-09 38.0 13.2 0.00016 21.8 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EDN09400.1 - 2.6e-09 36.8 18.2 0.0058 16.8 4.9 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN09400.1 - 2.3e-05 24.4 15.0 0.039 14.2 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDN09400.1 - 0.038 13.8 0.3 0.038 13.8 0.2 3.3 4 0 0 4 4 4 0 C2H2-type zinc finger Ribonuclease_T2 PF00445.13 EDN09401.1 - 3.7e-42 144.0 0.0 5.4e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family 4HBT_3 PF13622.1 EDN09402.1 - 5.4e-41 141.0 0.2 6.8e-41 140.6 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF155 PF02582.9 EDN09403.1 - 1.2e-45 155.5 0.0 1.9e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.15 EDN09404.1 - 1.2e-18 67.1 1.7 2.9e-17 62.6 0.0 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS DUF2422 PF10337.4 EDN09404.1 - 0.22 10.2 0.0 2.3 6.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) Vps39_1 PF10366.4 EDN09404.1 - 0.26 11.3 0.8 0.93 9.5 0.1 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 RAP1 PF07218.6 EDN09405.1 - 8.7 4.2 5.5 9.3 4.2 3.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CP2 PF04516.10 EDN09407.1 - 2.8e-87 291.6 0.0 4.2e-87 291.1 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Metallopep PF12044.3 EDN09410.1 - 5.6e-125 417.1 0.0 3.4e-110 368.4 0.0 2.2 1 1 1 2 2 2 2 Putative peptidase family DUF556 PF04476.8 EDN09410.1 - 0.006 15.8 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF556) Pkinase PF00069.20 EDN09411.1 - 0.0022 17.2 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GST_C_2 PF13410.1 EDN09413.1 - 9.8e-08 31.7 1.6 2.8e-07 30.3 1.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EDN09413.1 - 2.8e-07 30.6 0.0 5.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDN09413.1 - 3.3e-06 26.9 0.0 8.8e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EDN09413.1 - 0.018 15.2 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.11 EDN09414.1 - 2.8e-20 72.3 21.0 7.2e-17 61.1 10.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EDN09414.1 - 0.018 14.7 0.0 0.018 14.7 0.0 2.2 2 0 0 2 2 2 0 MFS_1 like family Lysis_S PF04971.7 EDN09414.1 - 0.064 12.9 0.1 0.25 11.0 0.1 2.0 1 0 0 1 1 1 0 Lysis protein S Herpes_env PF01673.13 EDN09414.1 - 0.086 11.3 0.1 0.12 10.8 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein JTB PF05439.7 EDN09414.1 - 0.16 11.7 0.0 8.6 6.1 0.0 2.8 3 0 0 3 3 3 0 Jumping translocation breakpoint protein (JTB) Multi_Drug_Res PF00893.14 EDN09414.1 - 0.67 10.4 6.5 0.92 10.0 1.0 2.8 2 0 0 2 2 2 0 Small Multidrug Resistance protein DUF4131 PF13567.1 EDN09414.1 - 5.1 6.4 13.8 0.94 8.8 0.4 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) zf-H2C2_5 PF13909.1 EDN09415.1 - 0.034 14.3 1.4 0.089 13.0 1.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain DNA_ligase_A_M PF01068.16 EDN09416.1 - 3.8e-48 163.5 0.0 1.8e-45 154.7 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EDN09416.1 - 1.5e-39 135.6 0.0 2.5e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DJ-1_PfpI PF01965.19 EDN09416.1 - 1.4e-15 56.9 0.0 2.9e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family DNA_ligase_A_C PF04679.10 EDN09416.1 - 6e-13 49.0 0.0 2.8e-12 46.8 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RINT1_TIP1 PF04437.8 EDN09417.1 - 1e-181 604.8 0.3 1e-181 604.8 0.2 2.1 2 0 0 2 2 2 2 RINT-1 / TIP-1 family Pyridoxal_deC PF00282.14 EDN09418.1 - 1.8e-77 260.2 0.0 2.7e-77 259.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EDN09418.1 - 8e-06 25.1 0.0 1.2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EDN09418.1 - 5e-05 22.2 0.0 8.9e-05 21.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DUF3427 PF11907.3 EDN09418.1 - 0.032 13.1 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) PUF PF00806.14 EDN09419.1 - 1.4e-08 33.7 0.0 3 7.4 0.0 6.9 7 0 0 7 7 7 3 Pumilio-family RNA binding repeat Taq-exonuc PF09281.5 EDN09419.1 - 0.025 14.7 0.8 0.083 13.0 0.0 2.4 3 0 0 3 3 3 0 Taq polymerase, exonuclease RCC1 PF00415.13 EDN09420.1 - 6.3e-30 103.1 3.0 3.8e-06 26.9 0.1 8.0 9 0 0 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDN09420.1 - 9.3e-14 50.6 25.1 1.2e-09 37.4 0.0 7.6 8 1 0 8 8 8 2 Regulator of chromosome condensation (RCC1) repeat CoA_transf_3 PF02515.12 EDN09420.1 - 0.019 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 CoA-transferase family III Sec34 PF04136.10 EDN09421.1 - 2.2e-26 92.4 1.9 4.1e-26 91.5 0.3 2.2 3 0 0 3 3 3 1 Sec34-like family Pkinase PF00069.20 EDN09422.1 - 4.3e-60 203.0 0.0 7.7e-60 202.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN09422.1 - 2.6e-42 144.7 0.0 3.8e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN09422.1 - 1.5e-10 40.5 0.0 1.1e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EDN09422.1 - 0.002 17.2 0.0 0.0048 15.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mur_ligase_M PF08245.7 EDN09425.1 - 0.15 12.1 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Mur ligase middle domain zf-C2H2 PF00096.21 EDN09426.1 - 1.2e-05 25.3 13.4 3.3e-05 23.9 1.9 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDN09426.1 - 2.2e-05 24.5 3.3 2.2e-05 24.5 2.3 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EDN09426.1 - 0.0012 18.8 0.7 0.0038 17.3 0.5 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EDN09426.1 - 0.0017 18.5 0.7 0.0017 18.5 0.5 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger Fork_head PF00250.13 EDN09428.1 - 2.2e-20 72.5 2.0 3.4e-19 68.6 1.4 2.3 1 1 0 1 1 1 1 Fork head domain FHA PF00498.21 EDN09428.1 - 3.4e-07 30.2 0.0 6.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Cwf_Cwc_15 PF04889.7 EDN09428.1 - 0.019 14.7 0.6 0.019 14.7 0.4 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein 7TMR-DISM_7TM PF07695.6 EDN09430.1 - 0.052 13.2 0.8 0.05 13.2 0.6 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling Calci_bind_CcbP PF11535.3 EDN09432.1 - 0.065 13.4 0.0 0.073 13.3 0.0 1.1 1 0 0 1 1 1 0 Calcium binding MGC-24 PF05283.6 EDN09432.1 - 3.8 7.2 8.5 4.8 6.9 5.9 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Metallopep PF12044.3 EDN09433.1 - 1.3e-140 468.5 0.0 1.8e-140 468.1 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.1 EDN09433.1 - 0.011 16.2 0.1 0.033 14.7 0.1 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EDN09433.1 - 0.016 15.2 1.5 0.031 14.3 1.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EDN09433.1 - 0.031 13.7 0.2 0.058 12.9 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EDN09433.1 - 0.041 12.7 0.6 0.075 11.8 0.4 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_5 PF13688.1 EDN09433.1 - 0.058 13.3 0.2 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 HTH_psq PF05225.11 EDN09434.1 - 0.1 12.1 0.1 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain ING PF12998.2 EDN09435.1 - 5.1e-05 23.4 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding V-set PF07686.12 EDN09437.1 - 0.019 14.8 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin V-set domain EB1 PF03271.12 EDN09438.1 - 3e-17 62.3 0.3 5.4e-17 61.5 0.2 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EDN09438.1 - 2.6e-07 30.6 1.1 4.3e-07 29.9 0.8 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.11 EDN09438.1 - 0.1 10.7 0.0 0.16 10.1 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like WD40 PF00400.27 EDN09439.1 - 6.1e-42 140.0 10.6 1.1e-09 37.7 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EDN09439.1 - 1.1e-08 34.6 0.2 2.9e-08 33.3 0.2 1.8 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.1 EDN09439.1 - 0.00083 18.8 0.6 0.17 11.2 0.1 2.6 2 1 1 3 3 3 1 PQQ-like domain F-box PF00646.28 EDN09439.1 - 0.0015 18.1 0.0 0.004 16.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain PQQ PF01011.16 EDN09439.1 - 0.027 14.0 0.2 10 5.8 0.0 3.5 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_3 PF13570.1 EDN09439.1 - 0.35 11.1 3.4 30 5.0 0.0 4.9 6 1 0 6 6 6 0 PQQ-like domain Nup160 PF11715.3 EDN09439.1 - 0.38 8.8 3.4 2.7 6.0 0.0 3.1 3 2 1 4 4 4 0 Nucleoporin Nup120/160 GFO_IDH_MocA PF01408.17 EDN09440.1 - 2.1e-09 37.9 0.0 3.9e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF1707 PF08044.6 EDN09440.1 - 0.097 12.4 0.0 12 5.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) E1-E2_ATPase PF00122.15 EDN09442.1 - 6.7e-60 201.9 0.6 1.6e-59 200.7 0.4 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDN09442.1 - 2.4e-43 147.8 9.7 2.4e-43 147.8 6.7 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDN09442.1 - 1.2e-23 84.6 0.1 1.2e-22 81.4 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN09442.1 - 3.7e-20 71.6 0.0 7.2e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EDN09442.1 - 1.2e-12 48.3 0.0 2.9e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDN09442.1 - 3.7e-08 32.7 0.1 2.2e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EDN09442.1 - 3.3e-05 23.5 0.2 0.0012 18.4 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase YjgP_YjgQ PF03739.9 EDN09442.1 - 0.0016 17.2 1.7 0.0096 14.7 0.6 2.2 2 0 0 2 2 2 1 Predicted permease YjgP/YjgQ family DUF3325 PF11804.3 EDN09442.1 - 0.039 13.8 0.0 0.039 13.8 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) SF3b1 PF08920.5 EDN09442.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Splicing factor 3B subunit 1 P16-Arc PF04699.9 EDN09443.1 - 3.3e-58 196.0 0.0 3.8e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF1720 PF08226.6 EDN09443.1 - 0.035 14.1 0.2 0.06 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1720) Methyltransf_11 PF08241.7 EDN09444.1 - 3e-09 37.2 0.0 6.3e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN09444.1 - 1.2e-06 28.3 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN09444.1 - 1.4e-06 28.7 0.0 3e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN09444.1 - 0.0036 16.9 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN09444.1 - 0.2 10.7 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Dynactin_p62 PF05502.8 EDN09445.1 - 8e-154 512.9 0.0 9.7e-154 512.6 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family Ribosomal_S7e PF01251.13 EDN09446.1 - 8e-80 266.7 0.1 8.9e-80 266.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e XFP_N PF09364.5 EDN09447.1 - 2.6e-155 516.6 0.0 3.4e-155 516.2 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 EDN09447.1 - 1.1e-66 224.1 0.1 5.5e-66 221.8 0.0 1.9 2 0 0 2 2 2 1 XFP C-terminal domain XFP PF03894.10 EDN09447.1 - 1.9e-66 223.0 0.0 3e-66 222.4 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.16 EDN09447.1 - 0.012 15.2 0.2 0.027 14.0 0.2 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.15 EDN09447.1 - 0.092 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Transketolase, C-terminal domain Acetate_kinase PF00871.12 EDN09448.1 - 4.2e-90 302.0 0.0 5.1e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family Ras PF00071.17 EDN09452.1 - 1.8e-55 186.7 0.0 3.1e-55 185.9 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EDN09452.1 - 2.7e-20 73.0 0.0 3.7e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN09452.1 - 1.4e-13 50.4 0.0 2.6e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDN09452.1 - 2.9e-06 26.6 0.0 4.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDN09452.1 - 6.1e-05 22.5 0.0 0.00018 20.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDN09452.1 - 0.0003 20.7 0.0 0.00046 20.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EDN09452.1 - 0.017 15.1 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.1 EDN09454.1 - 2.2e-06 27.8 0.5 7.4e-05 22.8 0.3 2.4 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EDN09454.1 - 4.2e-05 23.3 0.1 7.9e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 EDN09454.1 - 0.005 16.2 0.0 0.012 14.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDN09454.1 - 0.027 14.6 0.3 0.081 13.0 0.1 2.0 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EDN09454.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.9 EDN09454.1 - 0.083 12.6 0.0 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EDN09454.1 - 0.091 12.9 0.0 0.18 12.0 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CLU PF13236.1 EDN09456.1 - 2.5e-79 265.7 0.0 4e-79 265.1 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EDN09456.1 - 1.3e-52 178.1 0.0 3.9e-52 176.5 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EDN09456.1 - 8.2e-30 102.5 13.2 3.3e-10 39.7 0.0 4.4 2 1 3 6 6 6 4 Tetratricopeptide repeat CLU_N PF15044.1 EDN09456.1 - 3.4e-26 91.1 0.9 9.5e-26 89.7 0.6 1.8 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 EDN09456.1 - 7.2e-15 54.3 0.0 0.0011 18.8 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EDN09456.1 - 1e-05 25.1 0.8 0.4 10.3 0.0 3.7 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EDN09456.1 - 0.00068 19.3 5.1 0.35 10.8 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDN09456.1 - 0.0029 17.2 1.6 1.1 9.1 0.3 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDN09456.1 - 0.019 15.6 0.0 6.1 7.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDN09456.1 - 0.024 14.8 1.7 88 3.6 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat BCS1_N PF08740.6 EDN09459.1 - 1.1e-50 171.8 0.4 1.4e-50 171.4 0.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN09459.1 - 5.9e-17 62.1 0.0 1.1e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDN09459.1 - 2.2e-05 25.2 0.0 8.2e-05 23.4 0.0 2.0 1 1 1 2 2 1 1 AAA domain AAA_18 PF13238.1 EDN09459.1 - 3.1e-05 24.2 0.0 0.0013 19.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDN09459.1 - 0.00028 20.7 0.0 0.0011 18.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDN09459.1 - 0.00042 20.3 0.3 0.0021 18.0 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDN09459.1 - 0.0023 18.0 0.0 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EDN09459.1 - 0.0027 17.2 0.0 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 EDN09459.1 - 0.0049 15.8 0.0 0.009 14.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EDN09459.1 - 0.0071 16.6 0.0 0.019 15.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 EDN09459.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EDN09459.1 - 0.024 13.7 0.0 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 EDN09459.1 - 0.033 13.9 0.0 0.098 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EDN09459.1 - 0.052 13.3 0.0 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 EDN09459.1 - 0.055 13.6 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_21 PF13304.1 EDN09459.1 - 0.064 13.2 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EDN09459.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 EDN09459.1 - 0.13 11.4 0.0 0.59 9.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 EDN09459.1 - 0.16 12.5 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein KaiC PF06745.8 EDN09459.1 - 0.16 11.0 0.0 0.6 9.1 0.0 1.8 1 1 1 2 2 2 0 KaiC Cpn60_TCP1 PF00118.19 EDN09461.1 - 5.2e-166 553.0 0.3 5.9e-166 552.8 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 EDN09462.1 - 2.1e-43 147.2 15.9 2.9e-43 146.7 11.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) CAF-1_p150 PF11600.3 EDN09462.1 - 0.0019 17.6 14.9 0.0025 17.2 10.3 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal RNase_H2-Ydr279 PF09468.5 EDN09462.1 - 0.11 11.7 4.2 0.11 11.6 2.9 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Peptidase_S49_N PF08496.5 EDN09462.1 - 2.7 7.7 8.0 4.2 7.1 5.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Menin PF05053.8 EDN09462.1 - 2.9 5.9 7.7 3.7 5.5 5.3 1.2 1 0 0 1 1 1 0 Menin Kinesin PF00225.18 EDN09464.1 - 4.1e-57 193.4 0.0 6.5e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.10 EDN09464.1 - 0.03 14.1 1.7 0.081 12.7 1.2 1.8 1 0 0 1 1 1 0 Basic region leucine zipper Microtub_assoc PF07989.6 EDN09464.1 - 0.035 13.9 0.1 0.083 12.7 0.1 1.7 1 0 0 1 1 1 0 Microtubule associated DivIC PF04977.10 EDN09464.1 - 0.083 12.3 3.3 0.059 12.8 0.4 2.2 2 0 0 2 2 2 0 Septum formation initiator AAA_33 PF13671.1 EDN09464.1 - 0.15 11.9 2.1 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain TPR_11 PF13414.1 EDN09465.1 - 0.029 14.0 4.2 0.4 10.3 0.3 3.8 4 0 0 4 4 4 0 TPR repeat ChAPs PF09295.5 EDN09466.1 - 8.7e-156 518.6 0.0 1.1e-155 518.2 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EDN09466.1 - 6.1e-08 32.1 0.8 0.011 15.3 0.1 2.7 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDN09466.1 - 1.4e-06 27.7 1.5 0.0053 16.5 0.2 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDN09466.1 - 1.1e-05 24.8 0.8 0.15 11.7 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDN09466.1 - 1.8e-05 24.1 2.0 0.098 12.4 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDN09466.1 - 9.7e-05 22.6 0.4 0.13 12.6 0.0 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EDN09466.1 - 0.00028 20.9 0.2 0.79 9.8 0.0 3.6 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EDN09466.1 - 0.00065 19.5 0.1 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDN09466.1 - 0.00089 19.6 11.3 1.6 9.6 0.2 5.3 4 2 3 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDN09466.1 - 0.0064 16.2 2.5 0.57 10.1 0.1 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDN09466.1 - 0.012 16.2 0.1 14 6.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 EDN09466.1 - 0.018 14.0 1.0 0.31 10.0 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat YejG PF13989.1 EDN09466.1 - 0.061 13.3 0.4 0.3 11.1 0.0 2.3 3 0 0 3 3 3 0 YejG-like protein TPR_12 PF13424.1 EDN09466.1 - 0.14 12.0 8.2 6.8 6.6 0.2 4.5 3 2 3 6 6 6 0 Tetratricopeptide repeat Utp14 PF04615.8 EDN09467.1 - 1.6 6.7 23.5 1.9 6.5 16.3 1.0 1 0 0 1 1 1 0 Utp14 protein ERCC4 PF02732.10 EDN09468.1 - 1.6e-32 112.1 0.0 3e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain DUF4364 PF14277.1 EDN09468.1 - 0.066 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) E1-E2_ATPase PF00122.15 EDN09469.1 - 1.3e-53 181.4 0.1 2.1e-51 174.1 0.0 2.4 2 0 0 2 2 2 2 E1-E2 ATPase HMA PF00403.21 EDN09469.1 - 6.9e-37 125.4 1.5 6.2e-10 39.0 0.0 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 EDN09469.1 - 5.6e-35 121.7 0.1 9.4e-35 120.9 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDN09469.1 - 7e-19 68.7 0.0 1.9e-18 67.3 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDN09469.1 - 1.6e-07 31.1 0.7 0.0001 21.9 0.2 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase MafB19-deam PF14437.1 EDN09469.1 - 0.013 15.1 0.1 0.075 12.6 0.0 2.2 2 0 0 2 2 2 0 MafB19-like deaminase TFIIB PF00382.14 EDN09470.1 - 7.6e-33 112.1 3.3 5e-18 64.6 0.1 2.8 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EDN09470.1 - 5e-27 93.9 1.0 3.3e-26 91.3 0.0 2.6 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 EDN09470.1 - 6e-06 25.8 0.1 0.033 13.7 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 EDN09470.1 - 0.0005 19.3 2.7 0.0012 18.1 1.9 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.16 EDN09470.1 - 0.055 13.3 0.7 0.13 12.1 0.5 1.6 1 0 0 1 1 1 0 IBR domain DUF3446 PF11928.3 EDN09471.1 - 2.2 8.5 12.2 1 9.5 4.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) TPT PF03151.11 EDN09472.1 - 6.4e-26 90.8 11.4 6.4e-26 90.8 7.9 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EDN09472.1 - 0.00074 18.5 22.7 0.0045 15.9 15.7 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EDN09472.1 - 0.11 12.4 28.5 0.062 13.3 7.2 2.2 2 0 0 2 2 2 0 EamA-like transporter family ArsD PF06953.6 EDN09473.1 - 0.064 13.4 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 Arsenical resistance operon trans-acting repressor ArsD NAD_binding_8 PF13450.1 EDN09474.1 - 1e-08 35.0 0.1 2.4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EDN09474.1 - 7.5e-06 25.2 0.0 1.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EDN09474.1 - 2.4e-05 24.5 0.1 6.9e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDN09474.1 - 0.0072 15.4 0.1 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EDN09474.1 - 0.013 15.3 0.0 0.028 14.3 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN09474.1 - 0.037 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 EDN09474.1 - 0.097 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EDN09474.1 - 0.1 11.0 0.1 0.15 10.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 EDN09474.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDN09474.1 - 0.11 11.3 0.1 0.2 10.5 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pkinase PF00069.20 EDN09476.1 - 3.1e-62 210.0 0.0 4.2e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN09476.1 - 1.2e-30 106.4 0.0 3e-30 105.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDN09476.1 - 2.2e-05 23.6 0.0 3.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDN09476.1 - 0.00022 20.3 0.0 0.00071 18.6 0.0 1.8 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EDN09476.1 - 0.0027 17.4 0.0 0.0073 16.0 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDN09476.1 - 0.19 11.0 0.0 0.47 9.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Seryl_tRNA_N PF02403.17 EDN09478.1 - 8.6e-10 38.5 1.5 6.2e-08 32.6 1.0 2.3 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain tRNA-synt_2b PF00587.20 EDN09478.1 - 4.8e-05 22.9 0.0 0.24 10.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) FUSC PF04632.7 EDN09478.1 - 0.008 14.6 0.3 0.011 14.1 0.2 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family Atg14 PF10186.4 EDN09478.1 - 0.022 13.7 1.9 0.033 13.1 1.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IL6 PF00489.12 EDN09478.1 - 0.024 14.2 0.2 0.04 13.5 0.2 1.3 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family Spc7 PF08317.6 EDN09478.1 - 0.031 12.9 5.1 0.044 12.4 3.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MscS_porin PF12795.2 EDN09478.1 - 0.09 12.0 10.8 0.13 11.5 7.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain IncA PF04156.9 EDN09478.1 - 0.28 10.7 6.0 0.43 10.1 4.2 1.2 1 0 0 1 1 1 0 IncA protein Ax_dynein_light PF10211.4 EDN09478.1 - 0.45 10.3 4.7 0.79 9.5 3.2 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain TMCO5 PF14992.1 EDN09478.1 - 0.54 9.3 5.1 0.78 8.8 3.5 1.1 1 0 0 1 1 1 0 TMCO5 family DUF342 PF03961.8 EDN09478.1 - 0.84 7.9 3.2 1.4 7.2 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 EDN09478.1 - 0.98 8.3 4.6 1.5 7.7 3.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 EDN09478.1 - 1.6 8.3 6.3 2.6 7.6 4.4 1.2 1 0 0 1 1 1 0 Mnd1 family Cytochrom_B561 PF03188.11 EDN09479.1 - 2e-05 24.4 0.8 2e-05 24.4 0.6 1.9 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF3999 PF13163.1 EDN09479.1 - 0.00049 19.1 0.1 0.00052 19.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3999) AzlD PF05437.7 EDN09479.1 - 0.026 14.4 1.2 0.033 14.1 0.9 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) Cytochrom_B_N PF00033.14 EDN09479.1 - 0.037 13.3 2.2 0.076 12.3 1.6 1.5 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB PHO4 PF01384.15 EDN09479.1 - 0.053 12.1 0.4 0.056 12.0 0.3 1.1 1 0 0 1 1 1 0 Phosphate transporter family DUF4153 PF13687.1 EDN09479.1 - 0.17 11.3 2.6 0.27 10.7 1.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4153) COX15-CtaA PF02628.10 EDN09479.1 - 0.52 9.1 8.3 0.65 8.8 0.6 2.0 1 1 0 2 2 2 0 Cytochrome oxidase assembly protein Allantoicase PF03561.10 EDN09481.1 - 5.7e-88 292.0 0.0 9.3e-49 164.7 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat HATPase_c PF02518.21 EDN09482.1 - 8e-29 99.6 0.0 2.4e-28 98.0 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EDN09482.1 - 2e-22 79.2 0.1 5.6e-22 77.8 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EDN09482.1 - 1.2e-19 70.1 0.1 6.5e-19 67.7 0.0 2.5 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 EDN09482.1 - 6.3e-11 42.9 0.0 1.6e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EDN09482.1 - 9.3e-10 38.8 0.0 2.3e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.1 EDN09482.1 - 2.3e-09 37.4 0.5 3.1e-08 33.8 0.0 3.2 3 1 0 3 3 2 1 AAA ATPase domain GAF_3 PF13492.1 EDN09482.1 - 1.1e-07 32.0 0.0 3e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EDN09482.1 - 1.8e-07 30.6 0.0 7.1e-07 28.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain NACHT PF05729.7 EDN09482.1 - 3.9e-05 23.3 0.0 0.1 12.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain TPR_8 PF13181.1 EDN09482.1 - 0.00033 20.2 0.3 4.6 7.2 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat HATPase_c_3 PF13589.1 EDN09482.1 - 0.00078 19.1 0.0 0.0037 16.9 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ArgK PF03308.11 EDN09482.1 - 0.0013 17.5 0.0 0.0025 16.6 0.0 1.4 1 0 0 1 1 1 1 ArgK protein TPR_2 PF07719.12 EDN09482.1 - 0.023 14.6 7.9 5.9 7.0 0.1 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDN09482.1 - 0.42 11.1 2.2 6.4 7.4 0.8 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDN09482.1 - 2.1 9.1 0.0 2.1 9.1 0.0 5.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Pkinase PF00069.20 EDN09483.1 - 8.3e-09 34.9 0.1 1.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN09483.1 - 0.013 15.2 0.0 0.053 13.2 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN09483.1 - 0.06 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase 5_nucleotid PF05761.9 EDN09483.1 - 0.13 10.8 0.1 10 4.4 0.0 2.2 2 0 0 2 2 2 0 5' nucleotidase family Rnf-Nqr PF02508.9 EDN09485.1 - 0.095 12.2 3.1 0.078 12.5 1.1 1.7 1 1 0 1 1 1 0 Rnf-Nqr subunit, membrane protein 7TMR-DISM_7TM PF07695.6 EDN09485.1 - 0.39 10.3 8.6 0.32 10.6 2.1 2.2 1 1 0 2 2 2 0 7TM diverse intracellular signalling TPR_10 PF13374.1 EDN09486.1 - 0.077 12.9 0.1 0.52 10.3 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3826 PF12875.2 EDN09487.1 - 0.053 13.2 0.3 0.058 13.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) DUF3228 PF11539.3 EDN09487.1 - 0.055 12.5 0.1 0.063 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) RNase_H PF00075.19 EDN09489.1 - 7.6e-17 61.8 0.1 1.3e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN09489.1 - 0.062 13.0 0.1 1.3 8.8 0.1 2.5 1 1 0 1 1 1 0 Reverse transcriptase-like zf-C3HC4_3 PF13920.1 EDN09493.1 - 0.0015 18.1 9.4 0.0023 17.5 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Med28 PF11594.3 EDN09493.1 - 0.0066 16.6 0.8 0.01 16.0 0.6 1.2 1 0 0 1 1 1 1 Mediator complex subunit 28 DUF4618 PF15397.1 EDN09493.1 - 0.012 15.0 1.5 0.015 14.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) zf-RING_5 PF14634.1 EDN09493.1 - 0.019 14.6 7.2 0.032 13.9 5.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDN09493.1 - 0.024 14.6 8.3 0.042 13.8 5.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HAUS5 PF14817.1 EDN09493.1 - 0.032 12.8 0.9 0.04 12.4 0.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 zf-C3HC4 PF00097.20 EDN09493.1 - 0.049 13.2 7.7 0.09 12.4 5.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Macoilin PF09726.4 EDN09493.1 - 0.11 10.7 2.7 0.14 10.3 1.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Tox-REase-9 PF15650.1 EDN09493.1 - 0.13 12.4 0.0 2.3 8.4 0.1 2.1 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 9 FYVE_2 PF02318.11 EDN09493.1 - 0.39 10.6 5.6 0.62 9.9 3.9 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_2 PF13639.1 EDN09493.1 - 0.79 9.5 11.3 1.6 8.6 7.9 1.5 1 0 0 1 1 1 0 Ring finger domain DUF3435 PF11917.3 EDN09494.1 - 1.1e-35 123.2 0.0 3.7e-35 121.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) DUF371 PF04027.8 EDN09494.1 - 0.11 12.1 0.0 9.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF371) rve PF00665.21 EDN09496.1 - 2.9e-16 59.6 0.0 7e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EDN09496.1 - 7.4e-16 58.1 0.0 1.2e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EDN09496.1 - 3.1e-08 33.1 0.1 6.5e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF972 PF06156.8 EDN09496.1 - 0.0041 17.4 0.1 0.0041 17.4 0.1 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF972) MscS_porin PF12795.2 EDN09496.1 - 0.047 13.0 18.9 0.0094 15.2 10.5 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain IncA PF04156.9 EDN09496.1 - 0.055 13.0 12.8 0.13 11.8 8.9 1.5 1 0 0 1 1 1 0 IncA protein DUF3552 PF12072.3 EDN09496.1 - 0.069 12.3 16.5 0.088 12.0 10.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) gag_pre-integrs PF13976.1 EDN09496.1 - 0.12 11.9 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain IFT57 PF10498.4 EDN09496.1 - 0.15 10.8 6.8 0.28 9.8 4.7 1.4 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Spc7 PF08317.6 EDN09496.1 - 0.51 8.9 10.8 0.12 10.9 5.1 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein APG6 PF04111.7 EDN09496.1 - 0.62 9.0 10.3 1.2 8.1 7.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4200 PF13863.1 EDN09496.1 - 0.94 9.4 13.6 2.3 8.1 9.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Atg14 PF10186.4 EDN09496.1 - 1.8 7.4 7.7 3.4 6.5 5.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_DNA_bd PF12329.3 EDN09496.1 - 2.3 8.1 9.0 0.54 10.1 0.5 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EDN09496.1 - 2.5 7.9 12.6 5.5 6.8 8.7 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 EDN09496.1 - 2.8 5.6 5.1 4.4 5.0 3.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.1 EDN09496.1 - 4.5 5.6 6.1 7.4 4.8 4.2 1.2 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 EDN09496.1 - 8.7 4.6 3.1 15 3.8 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NQRA_SLBB PF11973.3 EDN09497.1 - 0.07 13.4 0.0 0.19 12.0 0.0 1.7 2 0 0 2 2 2 0 NQRA C-terminal domain HATPase_c PF02518.21 EDN09498.1 - 7.2e-23 80.4 0.7 3e-22 78.4 0.1 2.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EDN09498.1 - 3.4e-18 65.4 0.3 8.2e-18 64.1 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EDN09498.1 - 4.8e-06 26.5 0.2 0.063 13.3 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EDN09498.1 - 0.036 14.4 0.1 2.1 8.7 0.1 2.7 1 1 0 1 1 1 0 PAS domain HATPase_c_2 PF13581.1 EDN09498.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain RVT_1 PF00078.22 EDN09499.1 - 3.5e-20 72.2 0.0 5.3e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF837 PF05769.6 EDN09500.1 - 0.018 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF837) DDE_Tnp_1_7 PF13843.1 EDN09501.1 - 2e-24 86.2 0.0 1.2e-23 83.7 0.0 2.0 1 1 0 1 1 1 1 Transposase IS4 RasGEF PF00617.14 EDN09502.1 - 9.9e-46 155.8 1.4 4.1e-45 153.8 0.7 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EDN09502.1 - 9.4e-13 48.1 0.3 2.5e-12 46.8 0.2 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif Ank_2 PF12796.2 EDN09503.1 - 1.9e-18 66.5 0.0 5.7e-18 65.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DIL PF01843.14 EDN09503.1 - 5.8e-18 64.7 1.6 1.7e-11 43.9 0.1 2.4 2 0 0 2 2 2 2 DIL domain Ank PF00023.25 EDN09503.1 - 1.6e-15 55.9 0.0 8.1e-07 28.5 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EDN09503.1 - 4e-15 55.4 0.0 5.7e-08 32.7 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN09503.1 - 1.1e-09 38.5 0.0 0.00023 21.6 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN09503.1 - 1.9e-09 36.8 0.1 0.011 15.8 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat DUF2722 PF10846.3 EDN09504.1 - 9.3e-05 21.6 7.9 0.00015 20.9 5.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) RabGAP-TBC PF00566.13 EDN09506.1 - 2.7e-32 111.9 0.0 4.3e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mo25 PF08569.6 EDN09507.1 - 3.6e-130 433.8 0.1 4.1e-130 433.6 0.1 1.0 1 0 0 1 1 1 1 Mo25-like Pox_F15 PF04596.7 EDN09508.1 - 0.17 11.4 1.6 1.9 8.0 0.3 2.3 3 0 0 3 3 3 0 Poxvirus protein F15 Methyltransf_31 PF13847.1 EDN09509.1 - 2.2e-10 40.3 0.0 3.5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDN09509.1 - 2e-08 33.7 0.0 3.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EDN09509.1 - 2.4e-08 34.5 0.0 5.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN09509.1 - 2.1e-07 31.3 0.0 4.2e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN09509.1 - 1.6e-05 24.9 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN09509.1 - 2.2e-05 23.9 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EDN09509.1 - 3.3e-05 23.6 0.0 6.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN09509.1 - 0.00038 20.7 0.0 0.00091 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EDN09509.1 - 0.0014 17.4 0.0 0.0023 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5 PF05185.11 EDN09509.1 - 0.002 17.1 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.7 EDN09509.1 - 0.009 16.4 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EDN09509.1 - 0.036 14.0 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.15 EDN09509.1 - 0.048 12.7 0.0 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Met_10 PF02475.11 EDN09509.1 - 0.058 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein TehB PF03848.9 EDN09509.1 - 0.081 12.0 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 EDN09509.1 - 0.094 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EDN09509.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AAA PF00004.24 EDN09511.1 - 6.2e-44 149.3 0.3 4e-39 133.8 0.0 2.7 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EDN09511.1 - 1.3e-15 57.0 0.0 3e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 EDN09511.1 - 5.7e-10 38.6 0.1 5.8e-09 35.4 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.9 EDN09511.1 - 9.2e-06 25.6 0.0 3.6e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EDN09511.1 - 1.5e-05 25.1 0.0 0.00035 20.7 0.0 3.0 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.9 EDN09511.1 - 4.9e-05 23.0 0.0 0.0015 18.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDN09511.1 - 0.00038 20.5 0.1 0.0013 18.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EDN09511.1 - 0.00069 20.4 0.1 0.0031 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDN09511.1 - 0.00098 19.4 0.1 0.0045 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EDN09511.1 - 0.001 18.9 0.0 0.031 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EDN09511.1 - 0.0014 17.8 0.1 0.0046 16.1 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EDN09511.1 - 0.0031 17.6 0.0 0.036 14.2 0.0 2.3 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.7 EDN09511.1 - 0.0052 15.8 0.2 0.04 12.9 0.1 2.4 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EDN09511.1 - 0.0054 16.4 1.3 0.021 14.5 0.1 2.5 3 0 0 3 3 3 1 Part of AAA domain TIP49 PF06068.8 EDN09511.1 - 0.0068 15.1 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus KaiC PF06745.8 EDN09511.1 - 0.0084 15.2 0.1 0.018 14.1 0.1 1.5 1 0 0 1 1 1 1 KaiC IstB_IS21 PF01695.12 EDN09511.1 - 0.013 14.9 0.2 0.038 13.4 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.22 EDN09511.1 - 0.015 15.5 0.1 0.035 14.4 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 EDN09511.1 - 0.041 13.2 0.2 0.61 9.4 0.0 2.4 2 1 1 3 3 2 0 AAA domain AAA_33 PF13671.1 EDN09511.1 - 0.044 13.6 0.1 0.12 12.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 EDN09511.1 - 0.047 13.2 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EDN09511.1 - 0.085 12.5 0.5 4 7.0 0.2 2.3 1 1 1 2 2 2 0 Archaeal ATPase AAA_11 PF13086.1 EDN09511.1 - 0.13 11.8 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EDN09511.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EDN09511.1 - 0.18 10.7 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 EDN09511.1 - 0.23 10.3 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KxDL PF10241.4 EDN09513.1 - 6.4e-30 102.8 2.6 8e-30 102.5 1.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein Dodecin PF07311.7 EDN09513.1 - 0.1 12.6 0.2 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Dodecin HAD_2 PF13419.1 EDN09514.1 - 1.3e-05 25.5 0.0 1.5e-05 25.3 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NT5C PF06941.7 EDN09514.1 - 0.13 11.7 0.0 0.65 9.4 0.0 1.8 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Pkinase PF00069.20 EDN09515.1 - 5.7e-09 35.5 0.1 1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN09515.1 - 0.038 13.7 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN09515.1 - 0.056 12.5 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Bunya_NS-S_2 PF03231.8 EDN09515.1 - 0.15 10.6 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-S RIO1 PF01163.17 EDN09515.1 - 0.17 11.2 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Arginosuc_synth PF00764.14 EDN09516.1 - 8.6e-109 364.1 0.0 2.4e-108 362.6 0.0 1.6 1 1 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EDN09516.1 - 0.0012 18.3 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EDN09516.1 - 0.025 13.8 0.0 0.053 12.7 0.0 1.5 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EDN09516.1 - 0.064 11.7 0.0 0.09 11.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Peptidase_M13_N PF05649.8 EDN09517.1 - 1.3e-76 258.1 0.0 1.7e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EDN09517.1 - 4.8e-61 205.5 0.0 8.3e-61 204.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 Spore_III_AB PF09548.5 EDN09517.1 - 0.0048 16.6 0.0 2.5 7.8 0.0 3.2 3 0 0 3 3 3 2 Stage III sporulation protein AB (spore_III_AB) MAD PF05557.8 EDN09518.1 - 2.6e-52 177.9 70.0 4.5e-43 147.3 48.0 2.6 2 1 0 2 2 2 2 Mitotic checkpoint protein FliD_C PF07195.7 EDN09518.1 - 0.0024 17.2 1.9 0.0024 17.2 1.3 3.6 2 1 1 3 3 3 1 Flagellar hook-associated protein 2 C-terminus Tropomyosin_1 PF12718.2 EDN09518.1 - 0.0036 17.1 17.6 0.0036 17.1 12.2 6.6 3 3 2 5 5 5 1 Tropomyosin like Y_phosphatase3 PF13350.1 EDN09518.1 - 1.7 8.8 21.1 2.6 8.2 2.7 3.5 3 0 0 3 3 3 0 Tyrosine phosphatase family Reo_sigmaC PF04582.7 EDN09518.1 - 2.6 7.1 27.5 0.11 11.6 3.8 4.0 3 2 0 3 3 3 0 Reovirus sigma C capsid protein muHD PF10291.4 EDN09519.1 - 1.4e-88 296.4 0.2 2e-88 295.9 0.2 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Mnd1 PF03962.10 EDN09519.1 - 0.0016 18.1 7.1 0.0025 17.4 1.5 2.3 1 1 1 2 2 2 1 Mnd1 family Muted PF14942.1 EDN09519.1 - 0.0021 17.9 4.7 0.0047 16.8 3.3 1.6 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein Laminin_II PF06009.7 EDN09519.1 - 0.014 15.1 2.3 0.033 13.9 1.6 1.6 1 0 0 1 1 1 0 Laminin Domain II Fib_alpha PF08702.5 EDN09519.1 - 0.21 11.6 2.0 0.42 10.7 1.4 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 EDN09519.1 - 0.32 9.6 5.6 0.61 8.6 3.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Pkinase PF00069.20 EDN09520.1 - 2.1e-48 164.7 0.0 3e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN09520.1 - 5.5e-20 71.5 0.0 8.6e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN09520.1 - 9.9e-06 25.4 0.8 0.074 12.7 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EDN09520.1 - 0.00059 18.8 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EDN09520.1 - 0.025 13.9 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1470 PF07336.6 EDN09520.1 - 0.072 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) Kdo PF06293.9 EDN09520.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_9 PF14604.1 EDN09521.1 - 8.4e-09 34.8 0.0 1.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDN09521.1 - 2.8e-06 26.6 0.0 4.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EDN09521.1 - 6.7e-06 25.4 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF2668 PF10873.3 EDN09521.1 - 1.9 8.6 0.0 1.9 8.6 0.0 4.1 6 0 0 6 6 6 0 Protein of unknown function (DUF2668) OPT PF03169.10 EDN09522.1 - 3.9e-94 316.2 10.9 4.6e-94 316.0 7.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TraQ PF09679.5 EDN09522.1 - 0.067 13.1 0.4 0.067 13.1 0.3 2.2 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin chaperone (TraQ) OPT PF03169.10 EDN09523.1 - 1.2e-37 129.6 0.0 1.5e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1206 PF06724.6 EDN09523.1 - 0.69 9.7 3.9 0.63 9.8 0.1 2.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1206) Rav1p_C PF12234.3 EDN09524.1 - 3.3e-278 924.1 0.0 4e-278 923.8 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 EDN09524.1 - 6.8e-06 25.7 2.2 0.05 13.5 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Sfi1 PF08457.5 EDN09525.1 - 5.5e-103 345.3 67.4 1.9e-100 336.9 38.4 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein NDUF_B7 PF05676.8 EDN09526.1 - 0.0069 15.7 1.2 2.1 7.8 0.1 2.0 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.8 EDN09526.1 - 0.016 15.0 3.1 0.16 11.9 0.3 2.1 2 0 0 2 2 2 0 CHCH domain SCRL PF06876.7 EDN09526.1 - 0.071 13.0 0.4 0.09 12.7 0.3 1.1 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein Toxin_21 PF08091.6 EDN09526.1 - 0.14 11.8 0.9 0.17 11.5 0.1 1.6 2 0 0 2 2 2 0 Spider insecticidal peptide Cmc1 PF08583.5 EDN09526.1 - 0.25 11.1 3.5 0.56 10.0 2.5 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like tRNA-synt_1 PF00133.17 EDN09527.1 - 1.2e-163 545.4 0.0 5.7e-110 368.0 0.0 3.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EDN09527.1 - 7.3e-25 87.5 0.0 2.1e-24 86.0 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EDN09527.1 - 1.9e-10 39.9 0.0 2.4e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) Uso1_p115_head PF04869.9 EDN09528.1 - 1.6e-114 381.9 0.0 5.2e-114 380.2 0.0 1.9 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EDN09528.1 - 2.4e-08 33.9 23.2 2.4e-08 33.9 16.1 3.5 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.16 EDN09528.1 - 0.011 15.1 39.7 0.024 14.1 27.5 1.5 1 0 0 1 1 1 0 Intermediate filament protein DUF3584 PF12128.3 EDN09528.1 - 0.077 10.3 45.9 0.12 9.7 31.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Arm PF00514.18 EDN09528.1 - 0.28 11.0 2.6 41 4.2 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat AAA_13 PF13166.1 EDN09528.1 - 9.2 4.5 37.7 2 6.8 20.1 1.8 1 1 1 2 2 2 0 AAA domain XRN_N PF03159.13 EDN09529.1 - 3.3e-108 360.5 0.0 3.3e-108 360.5 0.0 2.1 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 EDN09529.1 - 0.0033 17.2 2.2 0.0067 16.2 1.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Atrophin-1 PF03154.10 EDN09529.1 - 2.2 6.3 14.0 0.091 10.8 5.9 1.4 2 0 0 2 2 2 0 Atrophin-1 family zf-CCHC_2 PF13696.1 EDN09529.1 - 3.2 7.3 6.1 0.27 10.7 0.6 1.9 2 0 0 2 2 2 0 Zinc knuckle Late_protein_L2 PF00513.13 EDN09530.1 - 0.065 12.0 0.1 0.081 11.7 0.1 1.2 1 0 0 1 1 1 0 Late Protein L2 DDE_3 PF13358.1 EDN09531.1 - 2.3e-08 33.8 1.1 3.5e-08 33.3 0.8 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease EPSP_synthase PF00275.15 EDN09532.1 - 3e-125 417.9 0.0 4.8e-125 417.2 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EDN09532.1 - 2.2e-99 331.6 0.0 3.1e-99 331.1 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EDN09532.1 - 3.1e-61 206.9 0.0 4.9e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 EDN09532.1 - 8.8e-25 86.5 0.0 2.6e-24 85.0 0.0 1.9 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EDN09532.1 - 3.5e-08 33.6 0.0 8.4e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SKI PF01202.17 EDN09532.1 - 4.7e-08 33.0 0.2 1.4e-06 28.2 0.0 3.1 3 1 0 3 3 3 1 Shikimate kinase Fe-ADH_2 PF13685.1 EDN09532.1 - 9.3e-08 31.6 0.0 2.6e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EDN09532.1 - 0.0057 17.4 0.0 0.026 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EDN09532.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Exo5 PF09810.4 EDN09533.1 - 2.4e-102 342.4 1.9 5.2e-101 338.0 1.3 2.2 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease Mpv17_PMP22 PF04117.7 EDN09533.1 - 2.2e-16 59.2 1.0 5e-16 58.0 0.7 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family PDDEXK_1 PF12705.2 EDN09533.1 - 0.029 13.7 0.3 0.071 12.4 0.0 1.8 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily DDE_Tnp_1_6 PF13751.1 EDN09533.1 - 0.1 12.5 0.6 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 Transposase DDE domain Histone PF00125.19 EDN09534.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDN09534.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDN09534.1 - 0.0036 17.3 0.3 0.0073 16.3 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EDN09534.1 - 0.04 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EDN09535.1 - 1.6e-07 31.3 0.2 1.7e-07 31.2 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EDN09535.1 - 5.3e-05 23.0 0.1 6.4e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EDN09535.1 - 0.00011 22.3 0.1 0.00013 22.1 0.0 1.0 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDN09535.1 - 0.0063 16.5 0.0 0.0078 16.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 EDN09535.1 - 0.035 13.8 0.0 0.035 13.8 0.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 EDN09535.1 - 0.08 12.6 0.0 0.087 12.5 0.0 1.1 1 0 0 1 1 1 0 Bromodomain associated RVT_1 PF00078.22 EDN09538.1 - 1.1e-24 86.9 0.0 2.5e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EDN09538.1 - 1.4e-05 24.7 1.0 2.8e-05 23.8 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EDN09538.1 - 0.17 11.5 1.5 0.48 10.1 1.0 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2 PF00096.21 EDN09543.1 - 1.5e-08 34.4 12.5 0.00026 21.1 0.9 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN09543.1 - 1.1e-06 28.5 14.8 0.002 18.3 0.9 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 EDN09543.1 - 3.3 7.8 7.8 1.6 8.9 1.2 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PAT1 PF09770.4 EDN09543.1 - 3.5 5.7 89.1 0.4 8.8 29.0 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Glyco_transf_22 PF03901.12 EDN09544.1 - 4.8e-87 292.6 22.1 5.6e-87 292.4 15.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.9 EDN09545.1 - 2.5e-48 163.4 1.2 2.5e-48 163.4 0.9 2.5 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region PRP3 PF08572.5 EDN09546.1 - 1.5e-70 237.0 1.7 2.5e-70 236.3 1.2 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EDN09546.1 - 8.3e-39 132.1 0.5 1.9e-38 131.0 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.12 EDN09547.1 - 5.6e-83 278.3 0.0 1.6e-82 276.9 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EDN09547.1 - 5.3e-26 91.6 4.4 4.4e-18 65.6 0.0 3.3 2 1 1 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 EDN09547.1 - 1.2e-23 83.5 0.0 5.3e-23 81.4 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_2 PF00623.15 EDN09547.1 - 4.6e-22 78.7 0.0 1.3e-21 77.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_4 PF05000.12 EDN09547.1 - 6.5e-18 64.4 0.0 2.2e-17 62.7 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Nop14 PF04147.7 EDN09547.1 - 0.023 12.6 13.6 0.045 11.6 9.4 1.4 1 0 0 1 1 1 0 Nop14-like family DUF1227 PF06777.6 EDN09548.1 - 8.5e-62 207.1 0.8 8.5e-62 207.1 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 EDN09548.1 - 6.4e-46 156.3 0.1 2.2e-45 154.6 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EDN09548.1 - 3.3e-29 101.5 6.5 7.9e-17 61.2 2.4 2.6 2 1 1 3 3 3 2 DEAD_2 Remorin_C PF03763.8 EDN09548.1 - 0.86 9.1 7.8 0.61 9.6 3.4 2.0 2 0 0 2 2 2 0 Remorin, C-terminal region LCM PF04072.9 EDN09550.1 - 7.8e-19 67.9 0.0 1.9e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase zf-C3HC4_3 PF13920.1 EDN09551.1 - 5.7e-06 25.8 3.4 1.1e-05 24.9 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN09551.1 - 3.2e-05 23.5 3.8 6.5e-05 22.5 2.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDN09551.1 - 0.001 18.6 4.8 0.0021 17.6 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDN09551.1 - 0.0011 18.7 5.2 0.0011 18.7 3.6 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDN09551.1 - 0.0017 18.3 6.1 0.0043 17.0 4.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EDN09551.1 - 0.0087 15.7 2.0 0.0087 15.7 1.4 3.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-MIZ PF02891.15 EDN09551.1 - 0.03 13.8 3.2 0.065 12.7 2.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.1 EDN09551.1 - 0.32 10.9 5.3 0.78 9.6 3.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ist1 PF03398.9 EDN09552.1 - 1.8e-34 118.5 0.5 3.1e-16 59.2 0.7 2.1 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway DUF2360 PF10152.4 EDN09552.1 - 0.16 12.2 7.8 0.37 11.0 0.9 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Ins_beta PF03488.9 EDN09555.1 - 0.24 11.2 2.8 3.2 7.6 1.9 2.3 1 1 0 1 1 1 0 Nematode insulin-related peptide beta type Clat_adaptor_s PF01217.15 EDN09557.1 - 1.3e-55 186.9 2.1 1.6e-55 186.7 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Acyltransferase PF01553.16 EDN09559.1 - 1.2e-07 31.2 0.0 1.5e-06 27.6 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase TP_methylase PF00590.15 EDN09560.1 - 4e-20 72.4 0.1 7e-20 71.6 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIID-18kDa PF02269.11 EDN09561.1 - 4e-32 109.8 0.3 4.3e-31 106.5 0.2 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Aminotran_1_2 PF00155.16 EDN09562.1 - 6.1e-56 189.9 0.0 7.2e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EDN09562.1 - 0.0049 15.2 0.1 0.0095 14.2 0.0 1.4 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 EDN09562.1 - 0.016 13.9 0.0 0.021 13.4 0.0 1.1 1 0 0 1 1 1 0 Allinase EF-hand_10 PF14788.1 EDN09562.1 - 0.16 11.6 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 EF hand BIR PF00653.16 EDN09563.1 - 1.4e-23 83.0 0.1 2.7e-23 82.1 0.1 1.5 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain F-box PF00646.28 EDN09565.1 - 0.0036 16.9 0.0 0.0079 15.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN09565.1 - 0.055 13.2 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 F-box-like DUF3446 PF11928.3 EDN09566.1 - 0.064 13.4 0.2 0.07 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) RNA_pol_Rpb5_C PF01191.14 EDN09567.1 - 1.6e-34 117.2 0.1 3e-34 116.4 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EDN09567.1 - 4.3e-33 113.5 0.1 7.5e-33 112.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EDN09567.1 - 0.029 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease cwf21 PF08312.7 EDN09567.1 - 0.18 11.7 1.3 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 cwf21 domain Occludin_ELL PF07303.8 EDN09568.1 - 0.014 16.1 33.8 0.71 10.6 1.5 4.3 3 2 1 4 4 4 0 Occludin homology domain DUF4191 PF13829.1 EDN09568.1 - 0.084 11.9 1.5 0.12 11.4 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4191) Baculo_PEP_C PF04513.7 EDN09568.1 - 0.45 10.3 12.9 0.83 9.4 1.2 3.7 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EDN09568.1 - 1.3 8.8 18.2 1 9.1 0.5 4.4 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) Cob_adeno_trans PF01923.13 EDN09568.1 - 1.6 8.4 21.4 2.7 7.7 1.6 4.8 2 1 3 5 5 5 0 Cobalamin adenosyltransferase DUF932 PF06067.6 EDN09568.1 - 2 7.6 12.2 0.24 10.6 2.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF932) Prominin PF05478.6 EDN09568.1 - 2.2 5.7 15.0 0.32 8.4 7.5 1.6 2 0 0 2 2 2 0 Prominin APG6 PF04111.7 EDN09568.1 - 3 6.8 49.8 0.013 14.5 10.2 3.2 2 1 1 3 3 3 0 Autophagy protein Apg6 DUF2730 PF10805.3 EDN09568.1 - 3 7.6 7.8 1 9.1 0.6 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF2730) IncA PF04156.9 EDN09568.1 - 3.2 7.3 45.5 0.22 11.1 8.7 4.6 2 1 1 3 3 3 0 IncA protein CENP-F_leu_zip PF10473.4 EDN09568.1 - 8.5 6.2 43.2 0.11 12.2 8.5 3.9 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Hemagglutinin PF00509.13 EDN09568.1 - 9.3 4.2 10.8 0.64 8.0 2.4 2.5 2 1 1 3 3 3 0 Haemagglutinin adh_short PF00106.20 EDN09569.1 - 5.5e-06 26.4 0.1 7.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Nol1_Nop2_Fmu PF01189.12 EDN09571.1 - 4.7e-09 36.0 0.0 0.00062 19.2 0.0 2.5 3 0 0 3 3 3 2 NOL1/NOP2/sun family PLAC8 PF04749.12 EDN09572.1 - 2.9e-27 95.3 17.5 3.4e-27 95.0 12.2 1.0 1 0 0 1 1 1 1 PLAC8 family Aldolase_II PF00596.16 EDN09573.1 - 9.9e-32 110.0 0.0 1.7e-30 105.9 0.0 2.1 1 1 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DEAD PF00270.24 EDN09574.1 - 1.9e-42 144.5 0.1 3.1e-42 143.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN09574.1 - 2.3e-20 72.2 0.2 5.9e-20 70.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN09574.1 - 0.0028 17.5 0.2 0.0053 16.6 0.2 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EDN09574.1 - 0.017 14.4 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 SecA DEAD-like domain Ank_2 PF12796.2 EDN09575.1 - 5.6e-59 196.4 16.0 2.7e-10 40.4 0.0 11.4 5 4 4 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EDN09575.1 - 9.6e-35 116.6 28.4 0.001 18.7 0.0 19.2 20 2 1 21 21 21 11 Ankyrin repeat Ank_4 PF13637.1 EDN09575.1 - 1.5e-22 79.5 17.4 1.3e-05 25.6 0.0 12.8 11 3 2 13 13 13 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN09575.1 - 1.7e-20 71.0 21.6 0.039 14.1 0.0 17.9 22 1 1 23 23 23 5 Ankyrin repeat Ank_5 PF13857.1 EDN09575.1 - 3.9e-10 39.6 22.5 0.0045 17.1 0.0 11.8 8 3 6 14 14 14 3 Ankyrin repeats (many copies) Adenylsucc_synt PF00709.16 EDN09576.1 - 1.2e-152 508.4 0.0 1.4e-152 508.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DnaJ PF00226.26 EDN09577.1 - 1.3e-14 53.6 8.6 3.8e-10 39.3 0.2 3.0 3 0 0 3 3 3 2 DnaJ domain Fungal_trans PF04082.13 EDN09578.1 - 0.0043 15.9 0.1 0.011 14.5 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EDN09579.1 - 6.1e-19 67.9 17.7 2.9e-15 55.8 7.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GTP1_OBG PF01018.17 EDN09580.1 - 6.8e-37 126.5 2.9 6.2e-27 94.1 2.1 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EDN09580.1 - 1.4e-21 76.6 0.0 4.1e-21 75.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDN09580.1 - 9.9e-08 31.4 0.1 2e-07 30.3 0.1 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EDN09580.1 - 0.029 13.1 0.1 0.42 9.3 0.0 2.3 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 EDN09580.1 - 0.035 14.3 0.7 0.09 13.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Arf PF00025.16 EDN09580.1 - 0.21 10.7 0.0 0.51 9.5 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Cupin_8 PF13621.1 EDN09581.1 - 1.6e-16 60.5 0.0 3.6e-16 59.4 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Homeobox_KN PF05920.6 EDN09582.1 - 1.6e-15 56.5 0.5 3.5e-15 55.4 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EDN09582.1 - 0.00038 20.0 0.1 0.00095 18.7 0.1 1.7 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 EDN09582.1 - 0.0058 16.8 25.3 0.011 15.9 1.9 4.9 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN09582.1 - 0.028 14.7 22.6 0.13 12.6 1.8 4.4 3 1 1 4 4 4 0 Zinc finger, C2H2 type HA PF03457.9 EDN09582.1 - 0.062 13.4 0.3 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 Helicase associated domain HTH_Tnp_Tc5 PF03221.11 EDN09582.1 - 0.068 12.9 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain zf-H2C2_2 PF13465.1 EDN09582.1 - 0.2 11.9 4.9 10 6.5 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger double domain UQ_con PF00179.21 EDN09583.1 - 1.3e-11 44.0 0.2 2.1e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDN09583.1 - 0.027 14.3 0.3 0.044 13.6 0.2 1.4 1 0 0 1 1 1 0 RWD domain 2OG-FeII_Oxy_2 PF13532.1 EDN09585.1 - 2.5e-18 66.6 0.0 3.6e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CUE PF02845.11 EDN09585.1 - 0.0052 16.2 0.0 0.0098 15.3 0.0 1.4 1 0 0 1 1 1 1 CUE domain DinI PF06183.8 EDN09585.1 - 0.099 12.6 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 DinI-like family WD40 PF00400.27 EDN09586.1 - 7.9e-23 79.4 17.7 5.1e-09 35.6 0.1 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat MFS_1 PF07690.11 EDN09587.1 - 2.4e-26 92.2 23.3 3.4e-26 91.8 16.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN09587.1 - 2.8e-19 69.0 5.2 3.9e-19 68.5 3.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EDN09587.1 - 2.5e-05 22.6 1.4 3.2e-05 22.3 1.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) XH PF03469.9 EDN09588.1 - 0.071 12.7 0.1 0.081 12.5 0.1 1.1 1 0 0 1 1 1 0 XH domain Aldolase_II PF00596.16 EDN09590.1 - 2.9e-12 46.5 0.1 3.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Stap_Strp_tox_C PF02876.12 EDN09590.1 - 0.048 13.8 0.9 0.2 11.8 0.1 2.2 3 0 0 3 3 3 0 Staphylococcal/Streptococcal toxin, beta-grasp domain 4HBT_3 PF13622.1 EDN09591.1 - 2.1e-45 155.5 2.9 3.2e-45 154.8 2.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EDN09591.1 - 1.4e-23 82.9 0.0 4.7e-12 45.6 0.0 3.4 3 1 0 3 3 3 3 Acyl-CoA thioesterase DUF3328 PF11807.3 EDN09593.1 - 1.7e-23 83.4 0.0 2.1e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) UBA_3 PF09288.5 EDN09593.1 - 0.049 13.2 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain DUF3328 PF11807.3 EDN09595.1 - 1.4e-20 73.8 6.9 1.6e-20 73.7 4.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Lactamase_B_2 PF12706.2 EDN09595.1 - 0.081 12.4 0.2 0.081 12.4 0.1 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Ank_2 PF12796.2 EDN09596.1 - 3.7e-38 129.7 1.0 5.1e-23 81.2 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDN09596.1 - 7e-27 91.8 0.2 3.1e-08 33.0 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EDN09596.1 - 4.6e-21 72.8 0.2 1.6e-05 24.6 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EDN09596.1 - 1.1e-20 73.5 0.1 4.5e-09 36.5 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN09596.1 - 1.8e-20 72.4 0.1 2.1e-08 34.1 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF3445 PF11927.3 EDN09597.1 - 3.9e-43 147.6 0.0 4.7e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) HSP70 PF00012.15 EDN09598.1 - 5.8e-07 27.8 0.1 2.3e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EDN09598.1 - 0.16 10.5 0.0 0.28 9.7 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein N2227 PF07942.7 EDN09599.1 - 3.1e-89 298.5 0.0 3.9e-89 298.2 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EDN09599.1 - 9.3e-06 25.4 0.0 3.8e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Myb_DNA-bind_6 PF13921.1 EDN09600.1 - 0.0013 18.8 0.1 0.0023 18.0 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN09600.1 - 0.035 14.1 0.1 0.071 13.1 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF4244 PF14029.1 EDN09600.1 - 0.036 13.1 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) zf-C3HC4 PF00097.20 EDN09601.1 - 0.00012 21.6 3.3 0.00021 20.8 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN09601.1 - 0.0025 17.8 5.3 0.0042 17.0 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DegS PF05384.6 EDN09601.1 - 0.0049 16.0 0.1 0.0072 15.5 0.1 1.2 1 0 0 1 1 1 1 Sensor protein DegS zf-RING_2 PF13639.1 EDN09601.1 - 0.011 15.5 7.2 0.02 14.7 5.0 1.5 1 0 0 1 1 1 0 Ring finger domain Med28 PF11594.3 EDN09601.1 - 0.021 15.0 0.2 0.033 14.4 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 28 Sec2p PF06428.6 EDN09601.1 - 0.036 13.8 0.4 0.058 13.2 0.3 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p NTR2 PF15458.1 EDN09601.1 - 0.089 12.0 0.3 0.11 11.7 0.2 1.1 1 0 0 1 1 1 0 Nineteen complex-related protein 2 HALZ PF02183.13 EDN09601.1 - 0.14 11.9 2.3 1.2 8.8 0.1 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper zf-C3HC4_3 PF13920.1 EDN09601.1 - 0.17 11.6 4.9 0.3 10.8 3.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN09601.1 - 0.22 11.3 5.4 0.41 10.3 3.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EDN09601.1 - 0.46 10.3 5.9 0.4 10.6 3.1 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING bZIP_2 PF07716.10 EDN09602.1 - 0.00077 19.2 7.7 0.0014 18.4 5.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EDN09602.1 - 0.007 16.3 8.4 0.017 15.1 5.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF2877 PF11392.3 EDN09602.1 - 0.015 15.5 0.9 0.73 10.0 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2877) RasGEF PF00617.14 EDN09603.1 - 6.9e-05 22.6 0.1 0.21 11.2 0.0 3.4 1 1 1 3 3 3 2 RasGEF domain HTH_12 PF08461.5 EDN09603.1 - 0.2 11.3 0.4 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain zf-C2H2_4 PF13894.1 EDN09605.1 - 2.1 8.8 5.3 25 5.5 0.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger RVT_1 PF00078.22 EDN09606.1 - 8e-34 116.8 0.0 1.4e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN09606.1 - 1.3e-23 82.8 0.0 3.5e-23 81.4 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN09606.1 - 9.7e-17 61.5 0.0 2.9e-16 60.0 0.0 1.9 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EDN09606.1 - 1.6e-09 38.1 0.7 4.6e-09 36.5 0.2 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family zf-C2H2 PF00096.21 EDN09606.1 - 0.21 11.9 0.1 0.21 11.9 0.0 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Myb_DNA-binding PF00249.26 EDN09607.1 - 7.9e-11 41.8 5.2 5.5e-08 32.7 0.1 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDN09607.1 - 3.5e-07 30.2 0.2 0.00017 21.5 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Coq4 PF05019.8 EDN09608.1 - 0.13 11.1 0.0 0.31 9.9 0.0 1.6 1 1 0 1 1 1 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SpecificRecomb PF10136.4 EDN09610.1 - 0.12 10.4 0.0 0.15 10.0 0.0 1.1 1 0 0 1 1 1 0 Site-specific recombinase APH PF01636.18 EDN09611.1 - 8.8e-07 28.8 0.7 0.0002 21.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EDN09611.1 - 2.6e-05 23.5 0.0 3.2e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EDN09611.1 - 8.4e-05 21.7 0.1 0.00016 20.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AceK PF06315.6 EDN09611.1 - 0.00089 17.6 0.1 0.0013 17.1 0.0 1.2 1 0 0 1 1 1 1 Isocitrate dehydrogenase kinase/phosphatase (AceK) Pkinase_Tyr PF07714.12 EDN09611.1 - 0.019 14.0 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.15 EDN09611.1 - 0.024 14.2 0.0 0.083 12.4 0.0 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EDN09611.1 - 0.1 11.2 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF3435 PF11917.3 EDN09613.1 - 7.4e-144 479.5 2.7 1.2e-125 419.5 0.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) Phage_integrase PF00589.17 EDN09613.1 - 4.7e-06 26.3 0.0 0.0006 19.5 0.0 2.3 2 0 0 2 2 2 2 Phage integrase family OmpH PF03938.9 EDN09613.1 - 0.42 10.5 0.0 0.42 10.5 0.0 2.7 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Fungal_trans PF04082.13 EDN09615.1 - 6.7e-19 67.7 0.1 1.7e-18 66.4 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Prefoldin_2 PF01920.15 EDN09616.1 - 7.8e-19 67.4 4.3 8.5e-19 67.2 3.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit Rbsn PF11464.3 EDN09616.1 - 0.01 15.3 0.6 0.01 15.3 0.4 1.8 2 0 0 2 2 2 0 Rabenosyn Rab binding domain Prefoldin PF02996.12 EDN09616.1 - 0.016 14.8 3.8 0.042 13.4 0.4 2.0 1 1 1 2 2 2 0 Prefoldin subunit ELF PF03317.8 EDN09616.1 - 0.061 12.6 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 ELF protein Spore_III_AF PF09581.5 EDN09616.1 - 0.099 12.4 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF2981 PF11200.3 EDN09616.1 - 0.11 11.5 0.1 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Seryl_tRNA_N PF02403.17 EDN09616.1 - 0.16 11.9 4.6 0.35 10.9 0.5 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc24 PF08286.6 EDN09616.1 - 0.21 11.3 2.1 5 6.8 0.0 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 COG2 PF06148.6 EDN09616.1 - 0.42 10.4 4.6 0.33 10.8 0.5 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 EDN09616.1 - 0.44 9.5 3.0 0.52 9.3 2.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TBPIP PF07106.8 EDN09616.1 - 1.2 8.6 5.6 0.2 11.1 0.4 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FlaC_arch PF05377.6 EDN09616.1 - 1.9 8.4 4.2 1.1 9.2 0.1 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EDN09616.1 - 2.3 7.7 8.7 0.29 10.6 1.6 1.8 1 1 0 1 1 1 0 IncA protein Tektin PF03148.9 EDN09616.1 - 4.2 5.8 7.3 1.4 7.3 0.6 2.0 1 1 1 2 2 2 0 Tektin family DUF4164 PF13747.1 EDN09616.1 - 5.4 7.2 7.8 1.4 9.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) ATG27 PF09451.5 EDN09617.1 - 1.2e-62 211.5 0.0 1.9e-62 210.9 0.0 1.3 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EDN09617.1 - 0.00011 21.9 0.0 0.0037 17.0 0.0 2.2 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat AAA_11 PF13086.1 EDN09617.1 - 0.035 13.6 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Glyco_tranf_2_3 PF13641.1 EDN09619.1 - 2.7e-07 30.6 0.1 3.7e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 APH PF01636.18 EDN09621.1 - 3.2e-09 36.9 0.0 5.8e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN09621.1 - 0.001 18.6 0.0 0.0022 17.5 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 EDN09621.1 - 0.04 12.9 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase BCS1_N PF08740.6 EDN09624.1 - 6.8e-17 61.6 0.1 8.4e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 BCS1 N terminal Elongin_A PF06881.6 EDN09624.1 - 0.071 13.5 0.1 0.086 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A bZIP_1 PF00170.16 EDN09625.1 - 5.4e-06 26.2 0.4 1.1e-05 25.2 0.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor Paramyxo_P PF01806.12 EDN09625.1 - 0.039 13.2 0.1 0.086 12.0 0.0 1.6 2 0 0 2 2 2 0 Paramyxovirinae P phosphoprotein C-terminal region CASP_C PF08172.7 EDN09625.1 - 0.045 12.7 2.6 3.6 6.5 0.0 2.2 2 0 0 2 2 2 0 CASP C terminal bZIP_2 PF07716.10 EDN09625.1 - 0.074 12.8 1.9 0.15 11.9 1.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper HTH_Tnp_Tc5 PF03221.11 EDN09627.1 - 0.0037 17.0 0.1 0.018 14.8 0.0 2.3 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_8 PF02954.14 EDN09627.1 - 0.02 14.4 2.0 0.28 10.7 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family HTH_psq PF05225.11 EDN09627.1 - 0.021 14.3 0.4 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 helix-turn-helix, Psq domain HTH_Tnp_IS630 PF01710.11 EDN09627.1 - 0.047 13.3 0.1 1.4 8.6 0.0 2.1 1 1 0 2 2 2 0 Transposase CD34_antigen PF06365.7 EDN09630.1 - 0.0001 22.0 0.6 0.00017 21.3 0.0 1.6 2 0 0 2 2 2 1 CD34/Podocalyxin family Mucin PF01456.12 EDN09630.1 - 0.059 13.1 13.4 0.14 11.8 9.3 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein CFEM PF05730.6 EDN09634.1 - 0.0011 18.6 4.9 0.0011 18.6 3.4 2.3 2 0 0 2 2 2 1 CFEM domain Sds3 PF08598.6 EDN09635.1 - 2e-55 187.5 7.5 4.1e-55 186.5 5.2 1.6 1 1 0 1 1 1 1 Sds3-like Glyco_hydro_72 PF03198.9 EDN09637.1 - 1.6e-90 303.3 0.1 4.4e-90 301.8 0.1 1.7 1 1 0 1 1 1 1 Glucanosyltransferase DUF3126 PF11324.3 EDN09637.1 - 0.057 13.0 0.0 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3126) Glyco_hydro_2_C PF02836.12 EDN09637.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Aldose_epim PF01263.15 EDN09639.1 - 2.7e-40 138.3 0.6 4.2e-37 127.8 0.4 2.0 1 1 0 1 1 1 1 Aldose 1-epimerase DUF4661 PF15576.1 EDN09639.1 - 0.2 11.2 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Actin PF00022.14 EDN09640.1 - 1.3e-25 89.6 0.0 2.2e-23 82.3 0.0 2.8 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EDN09640.1 - 0.025 13.1 0.0 0.22 10.0 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein XPG_I PF00867.13 EDN09641.1 - 3.9e-22 78.1 0.0 9.1e-22 76.9 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EDN09641.1 - 0.00019 21.6 0.0 0.00049 20.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain DEAD PF00270.24 EDN09642.1 - 3e-36 124.4 0.0 2.7e-35 121.3 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EDN09642.1 - 2.3e-21 75.0 0.0 4.2e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EDN09642.1 - 6.3e-19 67.6 0.0 2.8e-18 65.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN09642.1 - 0.0012 18.7 0.3 0.0099 15.7 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDN09642.1 - 0.02 15.0 0.7 0.21 11.7 0.2 2.7 2 1 0 2 2 2 0 AAA domain TipAS PF07739.8 EDN09642.1 - 2.4 8.5 7.6 5.1 7.4 5.2 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Phostensin PF13914.1 EDN09644.1 - 0.13 12.3 0.6 0.13 12.3 0.4 1.0 1 0 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region Ribosomal_S15 PF00312.17 EDN09645.1 - 9e-16 57.4 0.7 4.6e-15 55.1 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S15 PseudoU_synth_1 PF01416.15 EDN09646.1 - 1.2e-24 86.7 0.0 7.3e-21 74.5 0.0 2.7 3 0 0 3 3 3 2 tRNA pseudouridine synthase PIG-H PF10181.4 EDN09647.1 - 2.5e-27 94.2 0.5 4.3e-27 93.5 0.4 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component ubiquitin PF00240.18 EDN09648.1 - 0.0027 17.0 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 EDN09648.1 - 0.069 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Pribosyl_synth PF14572.1 EDN09649.1 - 1.9e-42 145.0 1.4 2e-37 128.7 0.3 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EDN09649.1 - 3e-34 117.2 0.0 1.7e-33 114.7 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EDN09649.1 - 3.3e-12 46.2 0.3 1.7e-11 43.9 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EDN09649.1 - 0.0079 15.4 0.1 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HSP70 PF00012.15 EDN09650.1 - 2e-21 75.5 8.1 6.8e-18 63.9 0.0 3.0 3 0 0 3 3 3 2 Hsp70 protein NPV_P10 PF05531.7 EDN09650.1 - 0.77 10.0 3.6 4.7 7.5 0.3 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Amidinotransf PF02274.12 EDN09651.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Amidinotransferase DUF2347 PF09804.4 EDN09652.1 - 2.7e-93 312.3 0.0 6.3e-93 311.0 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EDN09652.1 - 2.2e-35 122.3 0.0 3.7e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 EDN09652.1 - 2.6e-06 26.1 0.0 0.015 13.8 0.0 3.1 2 1 1 3 3 3 3 Transport protein Avl9 SPA PF08616.5 EDN09652.1 - 4.6e-05 23.1 0.0 0.00014 21.5 0.0 1.7 1 1 0 1 1 1 1 Stabilization of polarity axis EBP PF05241.7 EDN09653.1 - 1.1e-65 220.3 9.0 1.3e-65 220.1 6.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF640 PF04852.7 EDN09654.1 - 0.68 10.1 7.0 0.41 10.8 2.0 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF640) SNF2_N PF00176.18 EDN09656.1 - 4.5e-66 222.6 0.0 6.3e-66 222.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN09656.1 - 1.6e-12 47.0 0.0 4.4e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDN09656.1 - 2.1e-06 27.6 0.2 7.9e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ClpB_D2-small PF10431.4 EDN09657.1 - 2.1e-25 88.4 0.5 5.2e-25 87.1 0.4 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_2 PF07724.9 EDN09657.1 - 4.4e-10 39.7 0.0 1.4e-09 38.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF1192 PF06698.6 EDN09657.1 - 0.00057 19.6 0.4 0.0024 17.6 0.3 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) DUF4600 PF15372.1 EDN09657.1 - 0.49 10.6 3.8 9 6.5 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) Matrilin_ccoil PF10393.4 EDN09657.1 - 0.66 9.3 5.7 0.72 9.2 0.5 2.7 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DDE_3 PF13358.1 EDN09658.1 - 2.3e-08 33.8 1.1 3.5e-08 33.3 0.8 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4588 PF15251.1 EDN09659.1 - 0.0065 16.4 0.7 0.0094 15.9 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4588) DDE_Tnp_1_7 PF13843.1 EDN09660.1 - 1.4e-19 70.3 0.0 2e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 F-box PF00646.28 EDN09661.1 - 0.027 14.1 0.0 0.075 12.7 0.0 1.8 1 0 0 1 1 1 0 F-box domain LMP PF04778.7 EDN09661.1 - 0.099 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 LMP repeated region Pkinase PF00069.20 EDN09665.1 - 3e-24 85.5 0.0 5.2e-24 84.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN09665.1 - 2e-06 27.1 0.0 3.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDN09665.1 - 0.0021 17.1 0.1 0.0031 16.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDN09665.1 - 0.024 13.5 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EDN09665.1 - 0.042 13.5 1.1 0.099 12.3 0.6 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Myb_DNA-bind_6 PF13921.1 EDN09666.1 - 0.00032 20.7 0.1 0.00076 19.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Exo_endo_phos_2 PF14529.1 EDN09668.1 - 6.8e-16 57.9 0.0 3.5e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EDN09668.1 - 3.8e-05 23.1 0.1 8.6e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.18 EDN09668.1 - 0.0017 18.3 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF837 PF05769.6 EDN09668.1 - 0.096 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF837) DDE_1 PF03184.14 EDN09670.1 - 1.6e-40 138.5 0.0 4.4e-40 137.1 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN09670.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EDN09670.1 - 0.089 12.5 0.0 1.3 8.7 0.0 2.2 1 1 0 1 1 1 0 DDE superfamily endonuclease DDE_1 PF03184.14 EDN09671.1 - 9e-38 129.5 0.0 3.1e-37 127.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Abi PF02517.11 EDN09672.1 - 9.5e-14 51.3 7.0 9.5e-14 51.3 4.9 1.7 2 0 0 2 2 2 1 CAAX protease self-immunity Suc_Fer-like PF06999.7 EDN09673.1 - 4.3e-40 138.1 0.0 5.1e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like tRNA-synt_1 PF00133.17 EDN09674.1 - 1.3e-49 168.7 0.0 1.1e-35 122.7 0.0 5.0 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EDN09674.1 - 1.6e-39 135.1 0.0 2.3e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EDN09674.1 - 2.1e-26 92.5 4.0 5.6e-25 87.8 0.0 3.8 3 1 1 4 4 4 1 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EDN09674.1 - 1.3e-14 54.2 0.0 2.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 EDN09674.1 - 0.0016 17.2 0.0 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EDN09674.1 - 0.058 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.16 EDN09674.1 - 0.17 10.5 0.4 4.6 5.8 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain CEP44 PF15007.1 EDN09675.1 - 0.056 13.1 0.2 0.063 12.9 0.2 1.1 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 RVT_1 PF00078.22 EDN09676.1 - 6e-19 68.2 0.0 9.9e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN09676.1 - 1.6e-14 54.3 0.0 3.6e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 RNase H DDE_1 PF03184.14 EDN09677.1 - 4.5e-32 110.9 0.0 7.1e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN09677.1 - 3e-15 55.7 0.5 7.8e-15 54.4 0.1 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN09677.1 - 4.1e-06 26.2 0.1 1.1e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN09677.1 - 0.0017 18.0 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.15 EDN09677.1 - 0.08 12.9 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 Transposase 2-Hacid_dh_C PF02826.14 EDN09678.1 - 5.5e-50 168.9 0.0 8.2e-50 168.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDN09678.1 - 1.4e-15 56.9 0.0 1.9e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EDN09678.1 - 0.0003 20.6 0.0 0.0007 19.4 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF756 PF05506.7 EDN09678.1 - 0.14 12.6 0.4 3.7 8.0 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF756) DPM3 PF08285.6 EDN09680.1 - 0.12 12.2 0.4 0.18 11.6 0.3 1.2 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) FH2 PF02181.18 EDN09681.1 - 2.5e-80 270.1 2.6 2.5e-80 270.1 1.8 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EDN09681.1 - 3.6e-71 238.4 0.0 9.6e-71 237.0 0.0 1.7 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EDN09681.1 - 2.9e-52 176.9 6.1 5e-52 176.1 1.1 2.9 2 1 1 3 3 3 1 Diaphanous FH3 Domain TC1 PF15063.1 EDN09681.1 - 0.0036 16.8 0.4 1 8.9 0.0 2.8 2 0 0 2 2 2 2 Thyroid cancer protein 1 TrmE_N PF10396.4 EDN09684.1 - 1.6e-36 124.7 0.0 3.9e-36 123.4 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EDN09684.1 - 1.5e-21 76.5 0.1 1e-20 73.8 0.0 2.6 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EDN09684.1 - 1.1e-16 60.8 0.0 2.2e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDN09684.1 - 3.9e-05 23.5 0.0 7.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.13 EDN09684.1 - 0.00028 20.2 0.0 0.0012 18.1 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EDN09684.1 - 0.0003 20.2 0.1 0.05 13.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain F-box PF00646.28 EDN09684.1 - 0.00043 19.8 0.1 0.0016 17.9 0.1 2.1 1 0 0 1 1 1 1 F-box domain Miro PF08477.8 EDN09684.1 - 0.0018 18.7 0.0 0.0052 17.2 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EDN09684.1 - 0.089 13.0 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter zf-C2H2_4 PF13894.1 EDN09685.1 - 0.002 18.3 27.9 0.056 13.7 2.1 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN09685.1 - 0.0024 18.0 26.5 0.34 11.3 0.6 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EDN09685.1 - 0.081 12.8 1.1 0.081 12.8 0.7 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EDN09685.1 - 0.084 12.9 15.7 0.5 10.5 0.3 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) CD99L2 PF12301.3 EDN09686.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 Aconitase PF00330.15 EDN09687.1 - 1.5e-70 238.0 0.3 1.2e-43 149.3 0.0 2.9 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EDN09687.1 - 6.6e-23 81.2 0.0 1.3e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aminotran_5 PF00266.14 EDN09689.1 - 1.8e-24 86.2 0.0 7.3e-18 64.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V NAD_binding_1 PF00175.16 EDN09690.1 - 6.7e-06 26.6 0.0 7.1e-05 23.3 0.0 2.1 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EDN09690.1 - 0.00023 21.2 0.0 0.00067 19.7 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EDN09690.1 - 0.0052 16.6 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain AA_permease_2 PF13520.1 EDN09691.1 - 4.5e-61 206.6 35.7 6.4e-61 206.1 24.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN09691.1 - 7.9e-26 90.4 22.4 7.9e-26 90.4 15.5 2.0 2 0 0 2 2 2 1 Amino acid permease Methyltransf_26 PF13659.1 EDN09692.1 - 6.9e-11 42.2 1.0 1e-09 38.4 0.6 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN09692.1 - 3.3e-09 37.3 0.0 1.1e-08 35.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN09692.1 - 1.4e-07 31.1 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN09692.1 - 0.00036 20.8 0.0 0.00071 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN09692.1 - 0.00041 19.7 0.0 0.00096 18.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EDN09692.1 - 0.02 15.3 0.0 0.086 13.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EDN09692.1 - 0.059 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EDN09692.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Asp PF00026.18 EDN09693.1 - 2.3e-61 207.7 0.0 5.7e-61 206.5 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDN09693.1 - 1.4e-07 31.6 0.2 3.2e-05 23.9 0.0 2.9 2 1 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EDN09693.1 - 0.0016 18.8 0.1 7.7 7.0 0.0 3.4 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EDN09693.1 - 0.012 15.1 0.0 0.033 13.7 0.0 1.8 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Rep_fac_C PF08542.6 EDN09694.1 - 3.6e-21 74.9 0.1 9.6e-21 73.5 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EDN09694.1 - 1.7e-11 44.0 0.0 1.3e-09 37.9 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EDN09694.1 - 6.3e-11 42.5 0.0 1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EDN09694.1 - 1.1e-07 30.9 0.0 0.012 14.2 0.0 3.0 2 1 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EDN09694.1 - 8.2e-07 28.9 0.0 2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDN09694.1 - 3.5e-06 26.2 0.0 8.1e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EDN09694.1 - 1.2e-05 25.3 0.0 0.00051 20.0 0.0 2.5 1 1 2 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.13 EDN09694.1 - 1.5e-05 24.6 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EDN09694.1 - 3.5e-05 23.9 0.1 0.0095 16.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EDN09694.1 - 0.00011 21.7 0.1 0.036 13.4 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain AAA_3 PF07726.6 EDN09694.1 - 0.00016 21.2 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 EDN09694.1 - 0.00029 20.3 0.0 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DEAD PF00270.24 EDN09694.1 - 0.0012 18.4 0.1 0.12 11.8 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 EDN09694.1 - 0.0046 16.5 0.1 0.0077 15.8 0.1 1.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EDN09694.1 - 0.0049 16.0 0.1 0.055 12.6 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ArgK PF03308.11 EDN09694.1 - 0.006 15.3 0.1 0.015 14.1 0.0 1.5 1 1 1 2 2 2 1 ArgK protein AAA_19 PF13245.1 EDN09694.1 - 0.0071 16.0 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EDN09694.1 - 0.0095 15.3 0.0 0.12 11.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EDN09694.1 - 0.016 14.8 0.3 0.061 13.0 0.1 2.0 1 1 1 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.13 EDN09694.1 - 0.029 13.8 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.5 EDN09694.1 - 0.034 13.3 0.0 0.055 12.6 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SAGA-Tad1 PF12767.2 EDN09694.1 - 0.059 13.0 0.2 0.082 12.5 0.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AAA_18 PF13238.1 EDN09694.1 - 0.065 13.5 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 EDN09694.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EDN09694.1 - 0.082 11.7 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain FAD_binding_3 PF01494.14 EDN09695.1 - 4e-12 45.8 0.5 4.1e-08 32.6 0.0 2.8 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 EDN09695.1 - 3.3e-09 36.1 0.9 0.00097 18.1 1.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EDN09695.1 - 5e-09 35.3 3.0 0.00026 19.7 0.2 2.1 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EDN09695.1 - 2.7e-05 24.0 1.5 9.5e-05 22.3 1.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDN09695.1 - 0.00074 18.4 7.5 0.0066 15.3 4.7 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EDN09695.1 - 0.00075 18.5 0.5 0.0016 17.4 0.4 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EDN09695.1 - 0.0027 16.2 2.4 0.01 14.3 1.5 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EDN09695.1 - 0.0051 15.9 0.1 0.0071 15.4 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EDN09695.1 - 0.013 15.0 0.6 0.023 14.2 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 EDN09695.1 - 0.031 14.3 0.1 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDN09695.1 - 0.036 13.9 1.3 0.06 13.2 0.9 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN09695.1 - 0.052 13.3 1.0 0.11 12.2 0.1 2.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EDN09695.1 - 0.055 13.1 1.6 0.087 12.4 1.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EDN09695.1 - 0.51 9.1 6.1 0.87 8.3 4.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EDN09695.1 - 1.3 9.5 6.2 2.6 8.5 2.7 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Polysacc_deac_1 PF01522.16 EDN09696.1 - 7.1e-23 80.5 0.0 1.3e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EDN09696.1 - 0.017 14.5 0.0 0.037 13.4 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) Parvo_coat PF00740.13 EDN09696.1 - 0.06 12.3 0.2 0.08 11.8 0.1 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 adh_short_C2 PF13561.1 EDN09697.1 - 2.6e-16 60.1 0.1 3.1e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN09697.1 - 9.7e-16 58.1 0.2 1.3e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN09697.1 - 2.3e-06 27.3 0.8 1.5e-05 24.7 0.5 1.9 1 1 0 1 1 1 1 KR domain Amidase PF01425.16 EDN09698.1 - 2e-99 333.4 0.0 2.5e-99 333.0 0.0 1.0 1 0 0 1 1 1 1 Amidase FAD_binding_3 PF01494.14 EDN09699.1 - 3.1e-63 213.9 1.9 4.8e-61 206.7 1.3 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EDN09699.1 - 4e-36 124.1 0.0 6.8e-36 123.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 EDN09699.1 - 0.16 10.4 0.2 0.26 9.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Ald_Xan_dh_C2 PF02738.13 EDN09700.1 - 5.2e-179 596.0 0.1 6.9e-179 595.6 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EDN09700.1 - 1.3e-40 138.6 0.0 2.7e-40 137.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EDN09700.1 - 1.1e-34 118.3 0.1 8.7e-34 115.5 0.0 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EDN09700.1 - 6.6e-26 90.5 0.0 1.5e-25 89.4 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EDN09700.1 - 5.3e-25 87.1 0.0 1.3e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EDN09700.1 - 1.7e-08 34.1 0.2 1.4e-07 31.1 0.0 2.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fungal_trans PF04082.13 EDN09701.1 - 6e-30 103.9 3.4 8.9e-30 103.4 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EDN09702.1 - 7.7e-08 32.2 11.5 0.0014 18.8 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN09702.1 - 1.6e-07 31.1 11.1 0.00049 20.2 3.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EDN09702.1 - 0.0093 16.1 0.1 5 7.4 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type ApoA-II PF04711.8 EDN09703.1 - 0.036 13.9 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) DDE_Tnp_1_7 PF13843.1 EDN09704.1 - 7.4e-19 68.0 0.0 1.1e-15 57.5 0.0 2.1 1 1 1 2 2 2 2 Transposase IS4 RVT_1 PF00078.22 EDN09705.1 - 3.5e-27 95.1 0.0 6e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN09705.1 - 1.3e-14 54.6 0.0 3.5e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 RNase H DUF410 PF04190.8 EDN09707.1 - 8.3e-23 81.2 0.0 1e-22 80.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RAI1 PF08652.6 EDN09708.1 - 9.5e-30 102.1 0.0 1.7e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease IPPT PF01715.12 EDN09709.1 - 0.0014 17.7 0.1 1.1 8.2 0.0 2.2 2 0 0 2 2 2 2 IPP transferase Arginosuc_synth PF00764.14 EDN09709.1 - 0.034 13.1 0.0 0.052 12.5 0.0 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ABC_tran PF00005.22 EDN09710.1 - 2.3e-17 63.5 0.1 2.4e-16 60.2 0.1 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EDN09710.1 - 6.2e-10 39.5 1.5 0.00018 21.6 0.2 2.1 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EDN09710.1 - 2e-05 24.0 0.3 5.9e-05 22.5 0.1 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 EDN09710.1 - 2.8e-05 23.4 0.1 0.047 12.9 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EDN09710.1 - 9.5e-05 21.6 0.0 0.23 10.4 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EDN09710.1 - 0.0025 17.3 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.1 EDN09710.1 - 0.0039 17.5 0.1 0.0058 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDN09710.1 - 0.0063 15.9 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EDN09710.1 - 0.0075 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EDN09710.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EDN09710.1 - 0.014 15.4 0.4 0.026 14.5 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.18 EDN09710.1 - 0.018 15.0 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EDN09710.1 - 0.045 13.1 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 EDN09710.1 - 0.046 14.5 0.3 0.1 13.4 0.2 1.9 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EDN09710.1 - 0.048 13.4 0.2 0.071 12.9 0.1 1.2 1 0 0 1 1 1 0 Dynamin family AAA_28 PF13521.1 EDN09710.1 - 0.12 12.3 0.3 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EDN09710.1 - 0.12 12.2 0.1 3.1 7.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 EDN09710.1 - 0.21 8.8 0.0 0.28 8.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_22 PF13401.1 EDN09710.1 - 0.28 11.3 1.2 1.4 9.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 EDN09712.1 - 1.2e-42 142.3 15.4 2.5e-08 33.4 0.3 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 EDN09712.1 - 0.069 12.9 0.0 1.1 9.1 0.0 3.0 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Urm1 PF09138.6 EDN09713.1 - 4.1e-33 113.3 0.0 4.9e-33 113.1 0.0 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EDN09713.1 - 0.00039 20.7 0.0 0.0006 20.1 0.0 1.3 1 0 0 1 1 1 1 ThiS family 6PF2K PF01591.13 EDN09714.1 - 1.5e-62 210.6 0.0 2e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EDN09714.1 - 2.4e-14 53.6 0.9 8.5e-14 51.9 0.6 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EDN09714.1 - 5e-05 24.1 0.4 0.00083 20.1 0.3 2.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EDN09714.1 - 0.0093 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EDN09714.1 - 0.011 15.6 0.0 0.036 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EDN09714.1 - 0.093 12.3 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase Porin_3 PF01459.17 EDN09715.1 - 2e-81 273.2 0.5 2.4e-81 273.0 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 EDN09715.1 - 0.083 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term MIF4G_like PF09088.6 EDN09718.1 - 2.7e-58 196.5 0.1 9.1e-56 188.3 0.0 2.6 2 1 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 EDN09718.1 - 2.6e-51 174.3 0.0 5.3e-51 173.2 0.0 1.5 1 0 0 1 1 1 1 MIF4G like ANAPC15 PF15243.1 EDN09718.1 - 0.087 12.8 1.6 9 6.4 0.4 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 TMEM237 PF15383.1 EDN09721.1 - 0.0039 16.3 1.4 0.006 15.7 1.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 237 FA_hydroxylase PF04116.8 EDN09721.1 - 5.4 7.4 7.5 17 5.8 1.1 2.2 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily WD40 PF00400.27 EDN09722.1 - 3.8e-73 238.9 10.6 1.6e-12 46.7 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EDN09722.1 - 4e-26 91.0 11.8 5.8e-26 90.5 8.2 1.2 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 EDN09722.1 - 1.6e-06 26.6 1.1 0.00058 18.2 0.1 3.2 1 1 2 3 3 3 2 Cytochrome D1 heme domain eIF2A PF08662.6 EDN09722.1 - 0.00033 20.4 0.0 0.041 13.5 0.0 3.0 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EDN09722.1 - 0.0022 16.1 0.3 0.23 9.5 0.0 3.1 1 1 2 3 3 3 1 Nucleoporin Nup120/160 LXG PF04740.7 EDN09722.1 - 0.017 14.9 0.5 0.025 14.3 0.4 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily Nucleoporin_N PF08801.6 EDN09722.1 - 0.076 11.7 0.0 4.3 5.9 0.0 3.0 2 1 3 5 5 5 0 Nup133 N terminal like PD40 PF07676.7 EDN09722.1 - 0.097 12.3 0.6 43 3.9 0.0 4.6 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EDN09722.1 - 0.12 11.4 0.0 8.5 5.3 0.0 2.6 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 EDN09722.1 - 2 7.8 3.8 24 4.3 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature zf-H2C2_2 PF13465.1 EDN09724.1 - 3.3e-18 64.9 23.7 5.2e-07 29.6 2.2 4.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EDN09724.1 - 3.5e-16 58.4 27.6 8.9e-05 22.6 0.7 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN09724.1 - 5.8e-12 45.0 23.2 0.016 15.4 0.5 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EDN09724.1 - 0.015 15.4 9.8 0.17 12.1 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type MENTAL PF10457.4 EDN09724.1 - 0.034 13.7 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Cholesterol-capturing domain Mito_carr PF00153.22 EDN09725.1 - 3.3e-63 209.4 2.3 4.1e-21 74.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EDN09726.1 - 2.1e-34 116.9 0.0 1.7e-16 59.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN09726.1 - 2.9e-19 68.8 0.0 1.5e-08 34.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN09726.1 - 4e-15 55.4 0.0 7.2e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EDN09726.1 - 0.015 15.0 0.3 0.47 10.2 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 OB_RNB PF08206.6 EDN09726.1 - 0.096 12.2 0.3 6.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain Cas_Cas2CT1978 PF09707.5 EDN09726.1 - 0.13 12.2 0.0 11 6.0 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF2015 PF09435.5 EDN09727.1 - 9.3e-48 161.2 0.0 1e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Vps55 PF04133.9 EDN09727.1 - 0.039 13.7 0.2 0.047 13.4 0.1 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 55 Ribosomal_L28e PF01778.12 EDN09728.1 - 9.2e-41 138.9 0.6 1.4e-40 138.3 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family RVP_2 PF08284.6 EDN09730.1 - 0.089 12.7 0.0 0.089 12.7 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Glyco_hydro_35 PF01301.14 EDN09732.1 - 0.02 14.2 0.1 0.021 14.2 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 HTH_Tnp_Tc3_2 PF01498.13 EDN09733.1 - 3.2e-25 87.9 0.0 4.9e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_21 PF13276.1 EDN09733.1 - 0.0011 18.9 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 HTH-like domain HTH_32 PF13565.1 EDN09733.1 - 0.0067 17.2 0.0 0.011 16.4 0.0 1.5 1 1 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 EDN09733.1 - 0.025 14.7 0.0 0.043 13.9 0.0 1.5 1 1 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.1 EDN09733.1 - 0.054 13.1 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HTH_33 PF13592.1 EDN09733.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Ldh_1_N PF00056.18 EDN09734.1 - 4.6e-45 152.8 0.1 6.7e-45 152.3 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EDN09734.1 - 1.1e-36 126.1 0.0 1.6e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EDN09734.1 - 3.1e-06 26.1 0.0 4.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EDN09734.1 - 0.0022 18.0 0.2 0.0038 17.2 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EDN09734.1 - 0.012 14.6 0.2 0.089 11.8 0.0 2.4 2 2 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.11 EDN09734.1 - 0.017 14.4 0.1 1.9 7.7 0.0 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase TRAPP PF04051.11 EDN09735.1 - 1.8e-11 43.7 0.0 2.2e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PorB PF11565.3 EDN09735.1 - 0.04 14.1 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha helical Porin B PINIT PF14324.1 EDN09736.1 - 3.5e-42 143.8 0.1 6.2e-42 143.0 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EDN09736.1 - 5.3e-21 73.8 6.8 8.7e-21 73.1 4.7 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EDN09736.1 - 9.4e-08 31.3 0.2 3e-07 29.7 0.1 1.9 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 EDN09736.1 - 6.2e-07 28.8 1.9 1.3e-06 27.8 1.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit TerY-C PF15616.1 EDN09736.1 - 0.031 14.2 0.6 0.051 13.4 0.4 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain zf-Sec23_Sec24 PF04810.10 EDN09736.1 - 0.039 13.5 2.4 0.068 12.7 1.1 1.9 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger DAG1 PF05454.6 EDN09736.1 - 1.1 8.3 11.2 0.069 12.3 0.5 2.7 2 1 1 3 3 3 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF2423 PF10338.4 EDN09737.1 - 5.2e-20 71.1 2.4 5.2e-20 71.1 1.7 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) HMG14_17 PF01101.13 EDN09737.1 - 1.3 9.7 6.1 0.44 11.2 1.9 1.9 1 1 1 2 2 2 0 HMG14 and HMG17 Phosphodiest PF01663.17 EDN09738.1 - 2e-14 53.7 0.2 2.9e-12 46.5 0.1 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EDN09738.1 - 4.8e-05 22.6 0.0 0.00019 20.7 0.0 1.8 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 EDN09738.1 - 0.028 13.8 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily tRNA-synt_1b PF00579.20 EDN09739.1 - 3e-57 193.9 0.0 3e-56 190.6 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.17 EDN09740.1 - 1.5e-23 82.4 0.0 3.2e-23 81.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e DUF3579 PF12112.3 EDN09740.1 - 0.044 13.7 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3579) PNP_UDP_1 PF01048.15 EDN09741.1 - 4.1e-46 156.8 0.1 5.4e-46 156.4 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Fcf2 PF08698.6 EDN09742.1 - 2.5e-31 107.5 1.0 5.7e-31 106.4 0.0 2.0 2 1 0 2 2 2 1 Fcf2 pre-rRNA processing CBFD_NFYB_HMF PF00808.18 EDN09743.1 - 4.6e-19 68.2 0.6 6.7e-19 67.7 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDN09743.1 - 2.2e-12 46.8 0.1 3.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EDN09743.1 - 0.032 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.7 EDN09744.1 - 9.5e-119 396.3 1.8 1.1e-118 396.0 0.2 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG7 PF10191.4 EDN09744.1 - 4.4e-06 24.9 5.4 0.021 12.7 2.9 2.4 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) DUF2450 PF10475.4 EDN09744.1 - 0.00017 20.5 5.6 0.00038 19.4 3.9 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 EDN09744.1 - 0.0039 16.9 7.1 0.0046 16.7 1.2 2.8 2 1 0 2 2 2 1 Exocyst complex component Sec5 COG5 PF10392.4 EDN09744.1 - 0.0073 16.2 6.7 0.027 14.4 3.0 2.9 2 0 0 2 2 2 1 Golgi transport complex subunit 5 COG2 PF06148.6 EDN09744.1 - 0.33 10.8 11.0 0.056 13.3 3.9 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RRM_2 PF04059.7 EDN09745.1 - 3.2e-27 94.3 1.2 8.1e-27 93.0 0.8 1.7 1 1 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EDN09745.1 - 2.8e-09 36.4 0.2 0.022 14.3 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN09745.1 - 5.3e-05 22.9 0.1 0.00087 19.0 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN09745.1 - 0.0046 16.9 0.1 0.39 10.7 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) GTP_CH_N PF12471.3 EDN09746.1 - 3.6e-94 313.8 0.0 6.7e-94 312.9 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EDN09746.1 - 5.7e-17 61.4 0.0 1e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II Ribosomal_S3Ae PF01015.13 EDN09747.1 - 1.4e-77 259.4 5.3 1.7e-77 259.2 3.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydrolase_6 PF12697.2 EDN09748.1 - 3.5e-18 66.3 0.0 5.6e-18 65.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN09748.1 - 1.4e-15 57.5 0.0 2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN09748.1 - 1.9e-05 24.4 0.0 3.9e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EDN09748.1 - 0.0055 16.1 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.6 EDN09748.1 - 0.028 13.2 0.0 0.062 12.0 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase Ndr PF03096.9 EDN09748.1 - 0.048 12.1 0.0 0.1 11.0 0.0 1.7 1 1 0 1 1 1 0 Ndr family BAAT_C PF08840.6 EDN09748.1 - 0.082 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.15 EDN09748.1 - 0.099 12.8 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.2 EDN09748.1 - 0.1 11.4 0.0 0.64 8.8 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase enzyme Lipase_3 PF01764.20 EDN09748.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Ribonuclease_3 PF00636.21 EDN09749.1 - 5.3e-15 55.8 0.0 2.7e-14 53.5 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EDN09749.1 - 1.1e-11 44.7 0.0 2.5e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like MRP-S33 PF08293.6 EDN09750.1 - 1e-29 102.3 0.0 1.3e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 MutL_C PF08676.6 EDN09750.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 1 0 1 1 1 0 MutL C terminal dimerisation domain DUF382 PF04037.8 EDN09751.1 - 1.2e-61 206.1 1.4 2.5e-61 205.1 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 EDN09751.1 - 2.4e-21 74.8 6.3 6e-21 73.5 4.4 1.7 1 0 0 1 1 1 1 PSP DUF4611 PF15387.1 EDN09751.1 - 6.2 7.0 15.0 4 7.6 2.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) ER_lumen_recept PF00810.13 EDN09754.1 - 1.7e-37 129.1 0.3 2.7e-37 128.5 0.2 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor zf-H2C2 PF09337.5 EDN09755.1 - 0.0073 15.6 0.2 0.013 14.8 0.2 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Nucleo_P87 PF07267.6 EDN09757.1 - 0.45 9.1 9.1 0.35 9.4 4.0 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 HTH_7 PF02796.10 EDN09758.1 - 0.0036 17.1 0.0 0.01 15.6 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.1 EDN09758.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain XRCC4 PF06632.7 EDN09761.1 - 0.0009 18.1 16.3 0.016 14.0 11.3 2.3 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF1759 PF03564.10 EDN09761.1 - 0.036 13.8 2.9 0.055 13.2 1.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) PBP1_TM PF14812.1 EDN09761.1 - 0.11 12.7 0.0 0.11 12.7 0.0 3.0 3 1 1 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Matrilin_ccoil PF10393.4 EDN09761.1 - 0.18 11.2 2.7 6.7 6.1 0.2 2.7 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Nexin_C PF08628.7 EDN09761.1 - 0.4 10.7 4.8 0.15 12.1 1.2 1.9 2 0 0 2 2 2 0 Sorting nexin C terminal Molybdopterin PF00384.17 EDN09762.1 - 1.2e-71 241.6 0.0 2.8e-69 233.9 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 EDN09762.1 - 5.1e-19 67.2 0.1 1.4e-18 65.8 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EDN09762.1 - 5.2e-16 58.5 0.0 1.2e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2_4 PF13510.1 EDN09762.1 - 1.3e-08 34.5 0.1 9.5e-06 25.3 0.0 3.3 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.22 EDN09762.1 - 0.13 11.9 1.1 3.1 7.5 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.6 EDN09762.1 - 0.43 10.4 2.2 6.9 6.5 1.5 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_6 PF12837.2 EDN09762.1 - 0.47 10.4 3.2 0.48 10.4 0.9 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain Peptidase_S9 PF00326.16 EDN09764.1 - 8.1e-09 35.0 0.2 1.4e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EDN09764.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PUF PF00806.14 EDN09765.1 - 7.4e-35 116.4 2.9 8.8e-06 24.9 0.0 9.1 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat DUF2360 PF10152.4 EDN09766.1 - 4.3 7.6 6.6 6.4 7.0 4.6 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Ssl1 PF04056.9 EDN09767.1 - 9.6e-73 243.8 0.0 1.6e-71 239.9 0.0 2.1 1 1 1 2 2 2 1 Ssl1-like C1_4 PF07975.7 EDN09767.1 - 6.5e-16 58.0 8.2 6.5e-16 58.0 5.7 2.3 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EDN09767.1 - 1.1e-10 41.8 0.0 1.7e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EDN09767.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF4611 PF15387.1 EDN09767.1 - 1.2 9.3 5.6 2.4 8.3 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Stm1_N PF09598.5 EDN09767.1 - 1.3 9.7 7.4 4 8.2 5.2 1.8 1 0 0 1 1 1 0 Stm1 Nop14 PF04147.7 EDN09767.1 - 1.9 6.3 3.9 2.4 5.9 2.7 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_M1 PF01433.15 EDN09768.1 - 8.8e-132 439.8 0.1 1.4e-131 439.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EDN09768.1 - 1.1e-56 192.4 0.0 6.7e-52 176.7 0.0 2.6 2 1 1 3 3 3 2 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EDN09768.1 - 2.7e-22 79.1 1.3 6.3e-22 77.9 0.9 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Prenyltrans_2 PF13249.1 EDN09769.1 - 9.4e-39 132.3 12.9 1.5e-14 54.3 1.3 5.1 2 1 3 5 5 5 5 Prenyltransferase-like Prenyltrans_1 PF13243.1 EDN09769.1 - 5e-35 119.8 5.5 1.4e-15 57.2 0.3 5.0 4 2 0 4 4 4 4 Prenyltransferase-like Prenyltrans PF00432.16 EDN09769.1 - 1.9e-22 78.4 24.6 1.8e-05 24.2 0.2 6.6 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 EDN09769.1 - 1.7e-08 34.0 1.5 0.015 14.5 0.0 4.8 3 1 2 5 5 5 4 Pectic acid lyase A2M_comp PF07678.9 EDN09769.1 - 9.1e-07 28.3 1.7 0.01 15.0 0.0 4.2 5 0 0 5 5 5 2 A-macroglobulin complement component p450 PF00067.17 EDN09770.1 - 9.9e-28 96.8 0.0 1.4e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EDN09771.1 - 2.2e-26 92.3 0.0 3e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2781 PF10914.3 EDN09772.1 - 6.8e-33 113.5 10.9 7.8e-33 113.3 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) EBP PF05241.7 EDN09772.1 - 0.007 15.3 3.4 0.0084 15.1 2.4 1.2 1 0 0 1 1 1 1 Emopamil binding protein DUF420 PF04238.7 EDN09772.1 - 0.51 10.2 2.6 0.38 10.7 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF420) DUF2534 PF10749.4 EDN09772.1 - 1.3 9.0 4.1 0.53 10.2 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) zf-DHHC PF01529.15 EDN09772.1 - 3.1 7.1 5.8 0.56 9.5 0.6 2.2 2 1 0 2 2 2 0 DHHC palmitoyltransferase Ras PF00071.17 EDN09774.1 - 9.1e-66 220.2 0.4 1.1e-65 219.9 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN09774.1 - 1.1e-21 77.5 0.0 1.7e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN09774.1 - 1.1e-16 60.5 0.2 1.2e-16 60.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDN09774.1 - 1.5e-05 24.2 0.0 1.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDN09774.1 - 4.8e-05 22.8 0.1 0.00013 21.5 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDN09774.1 - 6.7e-05 22.8 0.0 9.6e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EDN09774.1 - 0.00025 21.2 0.1 0.14 12.3 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EDN09774.1 - 0.00065 18.9 0.0 0.00078 18.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EDN09774.1 - 0.0013 18.8 0.0 0.003 17.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EDN09774.1 - 0.0032 16.7 0.0 0.023 14.0 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EDN09774.1 - 0.0098 15.0 0.0 0.023 13.9 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDN09774.1 - 0.021 14.8 0.1 0.094 12.6 0.0 1.8 1 1 0 2 2 2 0 AAA ATPase domain Septin PF00735.13 EDN09774.1 - 0.029 13.3 0.1 0.21 10.5 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 EDN09774.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EDN09774.1 - 0.047 13.5 0.2 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDN09774.1 - 0.058 13.1 0.1 0.11 12.2 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EDN09774.1 - 0.059 13.6 0.0 0.13 12.6 0.0 1.8 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EDN09774.1 - 0.087 12.3 0.1 0.96 8.9 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mito_carr PF00153.22 EDN09775.1 - 3.9e-53 177.1 1.2 8.8e-18 63.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EDN09775.1 - 0.00089 19.0 0.2 0.0021 17.8 0.1 1.6 1 0 0 1 1 1 1 UcrQ family ATP_synt_I PF03899.10 EDN09775.1 - 0.088 12.9 7.2 1.4 9.1 0.0 3.4 2 1 1 3 3 3 0 ATP synthase I chain Shadoo PF14999.1 EDN09775.1 - 7.4 6.4 10.7 0.14 12.0 1.8 2.2 2 1 0 2 2 2 0 Shadow of prion protein, neuroprotective WD40 PF00400.27 EDN09776.1 - 1.9e-10 40.1 18.0 0.00028 20.6 0.1 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat WD40_alt PF14077.1 EDN09776.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif ATP-synt_ab PF00006.20 EDN09777.1 - 1.7e-61 207.4 0.0 3.1e-61 206.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDN09777.1 - 1.4e-25 90.0 0.6 2.6e-25 89.0 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDN09777.1 - 9.7e-25 86.5 2.2 2.9e-24 85.0 1.1 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 EDN09777.1 - 0.0025 17.2 0.1 0.024 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EDN09777.1 - 0.0042 16.8 0.0 0.018 14.7 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase DUF258 PF03193.11 EDN09777.1 - 0.015 14.4 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDN09777.1 - 0.018 15.0 1.1 0.23 11.4 0.3 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EDN09777.1 - 0.019 15.1 0.0 0.65 10.1 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EDN09777.1 - 0.024 14.3 0.1 0.066 12.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 EDN09777.1 - 0.028 14.1 0.1 1.3 8.6 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 EDN09777.1 - 0.031 13.4 0.1 0.052 12.6 0.1 1.4 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.17 EDN09777.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EDN09777.1 - 0.077 13.1 0.0 0.48 10.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain EKR PF10371.4 EDN09777.1 - 0.12 11.9 0.2 1.4 8.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function NB-ARC PF00931.17 EDN09777.1 - 0.16 10.8 0.9 0.62 8.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain Myb_DNA-bind_6 PF13921.1 EDN09779.1 - 0.041 13.9 3.9 0.15 12.1 2.7 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myticin-prepro PF10690.4 EDN09780.1 - 1.2 9.2 0.1 1.2 9.2 0.0 2.5 2 1 0 2 2 2 0 Myticin pre-proprotein from the mussel DUF4082 PF13313.1 EDN09781.1 - 0.094 12.1 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) Pkinase PF00069.20 EDN09782.1 - 1.8e-33 115.8 0.0 2.3e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN09782.1 - 1.6e-14 53.6 0.0 1.3e-13 50.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Myb_DNA-bind_6 PF13921.1 EDN09783.1 - 0.0012 18.8 3.2 0.0012 18.8 2.2 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN09783.1 - 0.0072 16.3 3.7 0.017 15.1 2.5 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Fungal_trans_2 PF11951.3 EDN09784.1 - 0.00028 19.6 0.2 0.00028 19.6 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3435 PF11917.3 EDN09785.1 - 7.3e-152 505.9 0.5 1.4e-151 505.0 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) POX PF07526.6 EDN09785.1 - 3.7 7.7 8.7 0.27 11.4 0.4 2.7 3 1 0 3 3 3 0 Associated with HOX Alpha-amylase_C PF02806.13 EDN09786.1 - 1.2e-20 73.3 0.0 2.5e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EDN09786.1 - 8.2e-19 68.1 0.0 1.4e-15 57.5 0.0 2.3 1 1 0 1 1 1 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 EDN09786.1 - 1.8e-14 53.5 0.0 4.1e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) adh_short PF00106.20 EDN09787.1 - 2e-21 76.6 3.5 3.2e-21 75.9 0.8 2.4 2 2 0 3 3 3 1 short chain dehydrogenase KR PF08659.5 EDN09787.1 - 2.2e-06 27.4 1.7 0.00012 21.8 0.7 2.6 1 1 1 2 2 2 1 KR domain DUF2316 PF10078.4 EDN09787.1 - 0.043 13.7 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) NAD_binding_10 PF13460.1 EDN09787.1 - 0.088 12.7 0.2 0.28 11.1 0.1 2.1 1 1 0 1 1 1 0 NADH(P)-binding DUF3088 PF11287.3 EDN09788.1 - 0.094 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) DUF2012 PF09430.5 EDN09789.1 - 4e-24 84.8 0.0 6.2e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) WW PF00397.21 EDN09789.1 - 1.3e-08 34.5 0.7 1.3e-08 34.5 0.5 2.5 2 0 0 2 2 2 1 WW domain YhhN PF07947.9 EDN09790.1 - 4.4e-34 117.4 3.7 4.3e-33 114.2 2.5 2.3 1 1 0 1 1 1 1 YhhN-like protein DUF3357 PF11837.3 EDN09790.1 - 0.037 13.8 1.5 0.8 9.5 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) NfeD PF01957.13 EDN09790.1 - 0.085 12.9 2.7 0.72 9.9 0.2 2.9 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding Med3 PF11593.3 EDN09790.1 - 5.7 6.0 9.0 8.5 5.4 6.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AMP-binding PF00501.23 EDN09791.1 - 6.3e-79 265.2 0.0 8.1e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme COX4 PF02936.9 EDN09792.1 - 1.8e-10 40.7 0.3 1.9e-10 40.6 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Cofilin_ADF PF00241.15 EDN09793.1 - 2.7e-20 72.5 0.1 3.5e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein UBN2_2 PF14227.1 EDN09793.1 - 0.089 12.3 0.2 0.7 9.4 0.1 2.2 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Cpn60_TCP1 PF00118.19 EDN09794.1 - 8.5e-119 397.3 10.6 9.8e-119 397.1 7.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 EDN09794.1 - 0.15 11.7 1.9 0.53 9.9 0.2 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) ATP-synt_Eps PF04627.8 EDN09796.1 - 1.3e-22 79.1 1.4 2.3e-22 78.2 1.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.8 EDN09797.1 - 6.7e-50 168.5 0.0 1.4e-49 167.5 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ORC5_C PF14630.1 EDN09798.1 - 1.8e-90 303.0 0.0 2.6e-90 302.5 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EDN09798.1 - 1.4e-14 54.5 0.0 3.8e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN09798.1 - 0.00023 21.2 0.0 0.00051 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EDN09798.1 - 0.033 13.0 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 EDN09798.1 - 0.048 13.3 0.0 4.3 6.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.9 EDN09798.1 - 0.061 13.0 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EDN09798.1 - 0.067 13.5 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EDN09798.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EDN09798.1 - 0.18 12.5 0.0 0.35 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EDN09798.1 - 0.28 10.8 0.0 0.63 9.6 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase PUF PF00806.14 EDN09801.1 - 4.9e-59 192.6 4.4 1.5e-07 30.4 0.0 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DDE_Tnp_1_7 PF13843.1 EDN09801.1 - 1.5e-14 53.8 0.0 3.2e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Transposase IS4 DnaB_bind PF10410.4 EDN09801.1 - 0.011 15.7 0.1 8.6 6.4 0.0 3.2 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase DDE_Tnp_1_7 PF13843.1 EDN09802.1 - 2.3e-30 105.8 0.0 3.2e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 RNA_pol_Rpb2_6 PF00562.23 EDN09804.1 - 1.8e-116 389.0 0.0 2.7e-116 388.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EDN09804.1 - 4.6e-54 182.4 0.9 6.6e-54 181.9 0.6 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EDN09804.1 - 8.3e-29 100.3 3.6 1.4e-28 99.6 2.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EDN09804.1 - 6.1e-28 96.9 0.1 1.5e-27 95.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EDN09804.1 - 2.8e-22 78.2 0.2 7.1e-22 76.9 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EDN09804.1 - 1.3e-19 69.6 0.0 2.8e-19 68.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RVT_1 PF00078.22 EDN09807.1 - 8.5e-26 90.6 0.0 1.8e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EDN09807.1 - 5.4e-16 58.0 0.8 1.3e-15 56.7 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EDN09807.1 - 1.5e-08 34.7 0.0 4.6e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EDN09807.1 - 0.0015 17.9 0.0 0.0057 16.0 0.0 2.0 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger gag-asp_proteas PF13975.1 EDN09807.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDN09807.1 - 0.054 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.15 EDN09807.1 - 0.097 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Nucleoplasmin PF03066.10 EDN09808.1 - 0.041 13.3 0.5 0.047 13.2 0.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin Trypan_PARP PF05887.6 EDN09808.1 - 0.2 11.4 0.6 0.24 11.2 0.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Sporozoite_P67 PF05642.6 EDN09808.1 - 0.28 8.9 3.2 0.32 8.7 2.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Bd3614_N PF14442.1 EDN09808.1 - 0.31 11.0 1.9 0.42 10.5 1.3 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal PBP1_TM PF14812.1 EDN09808.1 - 0.88 9.9 4.5 1.4 9.2 3.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glycos_transf_1 PF00534.15 EDN09809.1 - 5.3e-16 58.5 0.0 1.1e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EDN09809.1 - 6.1e-09 36.1 0.0 1.9e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EDN09809.1 - 0.00099 19.3 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 E1-E2_ATPase PF00122.15 EDN09810.1 - 2.4e-62 210.0 8.8 2.4e-62 210.0 6.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EDN09810.1 - 1.9e-22 80.7 0.0 5.4e-22 79.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDN09810.1 - 1.4e-12 48.2 0.0 3.6e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDN09810.1 - 1.7e-11 43.3 0.0 4e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EDN09810.1 - 0.0014 18.2 0.1 0.0029 17.2 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN09810.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Ribosomal_60s PF00428.14 EDN09810.1 - 2.6 8.5 19.2 0.43 11.0 9.4 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein RRM_1 PF00076.17 EDN09812.1 - 1.4e-05 24.6 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN09812.1 - 0.00024 20.8 0.0 0.00048 19.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN09812.1 - 0.00031 20.6 0.0 0.00066 19.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EDN09813.1 - 3.6e-05 23.9 0.1 0.00027 21.1 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase II-binding domain. Citrate_synt PF00285.16 EDN09814.1 - 2.4e-99 332.4 0.0 2.8e-99 332.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EDN09814.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone O-FucT PF10250.4 EDN09815.1 - 0.14 11.2 1.3 0.16 11.0 0.9 1.0 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Glypican PF01153.14 EDN09815.1 - 0.71 8.4 6.9 0.9 8.0 4.8 1.2 1 0 0 1 1 1 0 Glypican SprA-related PF12118.3 EDN09815.1 - 1.6 8.0 14.7 1.8 7.8 10.2 1.1 1 0 0 1 1 1 0 SprA-related family DHHW PF14286.1 EDN09815.1 - 2.6 7.2 5.3 3 7.0 3.7 1.0 1 0 0 1 1 1 0 DHHW protein CRT10 PF08728.5 EDN09815.1 - 3.9 5.3 5.7 4.2 5.2 3.9 1.0 1 0 0 1 1 1 0 CRT10 GAGA_bind PF06217.7 EDN09815.1 - 8.7 6.2 11.2 11 5.8 7.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3617 PF12276.3 EDN09816.1 - 0.67 9.3 4.4 0.19 11.1 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) Helitron_like_N PF14214.1 EDN09817.1 - 4.4e-27 94.9 0.4 1.2e-26 93.6 0.3 1.7 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EDN09817.1 - 3.3e-19 69.0 0.0 5.3e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase UvrD_C_2 PF13538.1 EDN09817.1 - 0.00014 21.9 0.0 0.00043 20.3 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EDN09817.1 - 0.00068 17.5 0.0 0.001 16.9 0.0 1.2 1 0 0 1 1 1 1 Helicase RNase_H PF00075.19 EDN09818.1 - 5.5e-08 33.2 0.0 9.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN09818.1 - 0.0049 16.6 0.2 0.013 15.2 0.1 1.8 1 1 0 1 1 1 1 Reverse transcriptase-like RVT_1 PF00078.22 EDN09819.1 - 3.9e-21 75.3 0.1 5.6e-21 74.8 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN09820.1 - 3.4e-10 39.5 0.1 4.8e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Rep-A_N PF04057.7 EDN09821.1 - 0.075 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain ClpB_D2-small PF10431.4 EDN09822.1 - 0.19 11.6 0.1 8.4 6.3 0.0 2.4 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein rve PF00665.21 EDN09823.1 - 0.0016 18.5 0.0 0.0045 17.0 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain RVT_2 PF07727.9 EDN09823.1 - 0.084 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Mito_carr PF00153.22 EDN09828.1 - 1.3e-27 95.3 4.3 5.4e-11 42.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M16 PF00675.15 EDN09829.1 - 4.3e-22 78.4 0.1 8.8e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EDN09829.1 - 5.8e-14 52.1 0.0 1.8e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain M16C_assoc PF08367.6 EDN09829.1 - 0.003 16.4 0.0 0.0068 15.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16C associated RNA_pol_Rpc82 PF05645.8 EDN09830.1 - 6.5e-32 111.0 0.0 1.4e-29 103.4 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EDN09830.1 - 6.9e-14 51.4 4.2 2.1e-05 24.2 0.2 4.4 3 1 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EDN09830.1 - 7.8e-12 44.6 1.4 8e-08 31.7 0.1 2.5 2 0 0 2 2 2 2 TFIIE alpha subunit TrmB PF01978.14 EDN09830.1 - 0.021 14.5 0.8 2.6 7.8 0.1 3.3 4 0 0 4 4 4 0 Sugar-specific transcriptional regulator TrmB F-box-like PF12937.2 EDN09831.1 - 0.00012 21.7 0.6 0.00032 20.3 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN09831.1 - 0.058 13.0 0.8 0.19 11.4 0.5 1.8 1 0 0 1 1 1 0 F-box domain Ras PF00071.17 EDN09832.1 - 1.9e-61 206.1 0.9 2.3e-61 205.8 0.6 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN09832.1 - 4.5e-22 78.7 0.0 6.7e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN09832.1 - 1.3e-14 53.8 0.2 1.7e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EDN09832.1 - 1e-07 31.8 0.1 1.6e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDN09832.1 - 5.6e-06 25.9 0.3 2e-05 24.1 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDN09832.1 - 6.2e-05 22.2 0.1 8.2e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EDN09832.1 - 0.0022 18.1 0.1 0.0068 16.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 EDN09832.1 - 0.0031 16.7 0.1 0.0045 16.1 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EDN09832.1 - 0.005 16.1 0.5 0.056 12.7 0.4 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_15 PF13175.1 EDN09832.1 - 0.006 15.6 0.0 0.0081 15.2 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EDN09832.1 - 0.011 15.9 0.1 0.02 15.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EDN09832.1 - 0.012 15.2 0.4 0.044 13.3 0.1 2.1 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.5 EDN09832.1 - 0.013 14.7 0.1 0.023 13.9 0.1 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EDN09832.1 - 0.014 14.8 0.0 0.048 13.1 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EDN09832.1 - 0.015 15.1 0.1 0.049 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EDN09832.1 - 0.037 13.9 0.4 0.069 13.1 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 EDN09832.1 - 0.051 13.2 0.2 0.09 12.4 0.1 1.6 1 1 0 1 1 1 0 Archaeal ATPase NTPase_1 PF03266.10 EDN09832.1 - 0.056 13.1 0.1 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 NTPase UDG PF03167.14 EDN09832.1 - 0.079 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily AAA_29 PF13555.1 EDN09832.1 - 0.099 12.1 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EDN09832.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Chromo PF00385.19 EDN09833.1 - 7.4e-10 38.3 0.1 1.5e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_2 PF07724.9 EDN09835.1 - 2.3e-36 125.3 0.0 4e-35 121.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EDN09835.1 - 1.6e-13 51.0 0.0 2.8e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EDN09835.1 - 1.8e-08 34.1 0.0 3.8e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EDN09835.1 - 6.6e-06 25.8 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EDN09835.1 - 0.00073 18.7 0.1 0.011 14.9 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EDN09835.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 EDN09835.1 - 0.0021 18.2 0.1 0.022 14.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN09835.1 - 0.0021 18.8 0.0 0.0049 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EDN09835.1 - 0.0037 16.8 0.0 0.0076 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EDN09835.1 - 0.004 16.6 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 EDN09835.1 - 0.0053 16.7 0.1 0.0053 16.7 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EDN09835.1 - 0.0069 15.4 0.3 0.14 11.2 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EDN09835.1 - 0.052 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EDN09835.1 - 0.087 12.4 0.1 0.24 10.9 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EDN09835.1 - 0.096 12.0 0.6 0.29 10.5 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EDN09835.1 - 0.14 12.4 1.4 0.43 10.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EDN09835.1 - 0.34 10.7 2.9 0.5 10.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain RVT_1 PF00078.22 EDN09836.1 - 8.2e-35 120.0 0.0 1.6e-34 119.1 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN09836.1 - 1.9e-15 56.5 0.0 9.7e-15 54.2 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN09836.1 - 0.00051 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EDN09836.1 - 0.00054 19.7 4.1 0.00054 19.7 2.9 2.3 2 0 0 2 2 2 1 Zinc knuckle DUF837 PF05769.6 EDN09836.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF837) zf-CCHC_4 PF14392.1 EDN09836.1 - 0.98 9.1 12.8 3.1 7.5 1.0 2.6 1 1 1 2 2 2 0 Zinc knuckle Cys_Met_Meta_PP PF01053.15 EDN09837.1 - 2.2e-148 493.7 0.0 2.5e-148 493.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EDN09837.1 - 1.7e-12 47.0 0.1 3.4e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EDN09837.1 - 6.3e-09 35.2 0.0 9.4e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EDN09837.1 - 4.1e-07 29.0 0.1 9.8e-07 27.8 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EDN09837.1 - 0.00024 20.3 0.0 0.00035 19.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EDN09837.1 - 0.013 14.1 0.0 0.019 13.6 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 EDN09837.1 - 0.041 12.1 0.0 0.056 11.7 0.0 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 EDN09837.1 - 0.15 10.4 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) RVT_2 PF07727.9 EDN09839.1 - 2.4e-52 177.3 0.0 3.5e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN09839.1 - 6.6e-15 55.2 0.0 1.8e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF4219 PF13961.1 EDN09839.1 - 0.018 14.4 1.9 0.041 13.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) gag_pre-integrs PF13976.1 EDN09839.1 - 0.021 14.4 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain CAP_N PF01213.14 EDN09839.1 - 2.6 7.2 8.8 7.6 5.7 6.1 1.8 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CLPTM1 PF05602.7 EDN09840.1 - 0.098 11.3 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) RNase_H PF00075.19 EDN09841.1 - 3.8e-15 56.3 0.0 6.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN09841.1 - 0.097 12.4 0.1 0.34 10.7 0.1 1.9 1 1 0 1 1 1 0 Reverse transcriptase-like DUF865 PF05906.6 EDN09843.1 - 1.5 8.4 9.2 36 4.0 0.0 4.5 2 1 3 5 5 5 0 Herpesvirus-7 repeat of unknown function (DUF865) DUF3505 PF12013.3 EDN09845.1 - 2.2e-15 56.8 0.1 5e-15 55.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) ACTH_domain PF00976.13 EDN09846.1 - 0.88 9.4 6.2 1.2 8.9 0.1 3.2 3 0 0 3 3 3 0 Corticotropin ACTH domain DUF3636 PF12331.3 EDN09848.1 - 1.9e-59 199.5 0.0 3.2e-59 198.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) DUF4358 PF14270.1 EDN09848.1 - 0.022 14.6 1.2 0.049 13.4 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) DUF755 PF05501.6 EDN09848.1 - 0.47 10.5 3.5 0.75 9.8 1.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF755) GDPD PF03009.12 EDN09849.1 - 1.5e-16 60.6 0.0 7e-15 55.2 0.0 2.2 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family RVT_2 PF07727.9 EDN09852.1 - 2.5e-49 167.4 0.0 3.9e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 EDN09852.1 - 1.4e-12 47.0 0.3 3.3e-12 45.8 0.2 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 EDN09852.1 - 4.9e-06 26.6 0.0 2.2e-05 24.5 0.0 2.0 1 1 1 2 2 2 1 Integrase core domain DDE_Tnp_1_7 PF13843.1 EDN09853.1 - 2.5e-42 145.2 0.3 4.5e-42 144.3 0.0 1.5 2 0 0 2 2 2 1 Transposase IS4 Ribosomal_L3 PF00297.17 EDN09854.1 - 3e-35 121.9 2.7 8.8e-34 117.0 1.9 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 RIC3 PF15361.1 EDN09855.1 - 0.04 14.1 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF3378 PF11858.3 EDN09855.1 - 0.14 12.2 0.0 0.91 9.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) VGCC_beta4Aa_N PF12052.3 EDN09855.1 - 1.3 8.9 3.9 2.5 8.0 2.7 1.4 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF788 PF05620.6 EDN09855.1 - 4 7.2 5.0 20 5.0 3.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF788) CTP_transf_2 PF01467.21 EDN09856.1 - 4.6e-17 62.4 0.0 7.5e-14 52.0 0.0 3.2 3 0 0 3 3 3 2 Cytidylyltransferase G6PD_bact PF10786.4 EDN09857.1 - 0.058 12.8 0.3 0.074 12.4 0.2 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) DDE_1 PF03184.14 EDN09858.1 - 2.5e-36 124.8 0.0 7.6e-36 123.2 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease MRP-S26 PF14943.1 EDN09858.1 - 0.08 12.4 10.6 0.18 11.3 7.3 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 CAF-1_p150 PF11600.3 EDN09858.1 - 1.1 8.6 17.5 1.6 8.0 12.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4355 PF14265.1 EDN09858.1 - 1.6 8.6 15.7 26 4.8 10.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) PC4 PF02229.11 EDN09861.1 - 6e-22 76.6 0.1 1e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Anophelin PF10731.4 EDN09861.1 - 0.67 10.0 2.7 4.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Hydantoinase_B PF02538.9 EDN09862.1 - 1.4e-27 96.1 0.7 1.6e-27 95.9 0.5 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_B PF02538.9 EDN09863.1 - 0.0048 15.1 0.0 0.0048 15.1 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Exo_endo_phos_2 PF14529.1 EDN09864.1 - 3e-13 49.4 0.0 6.7e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF624 PF04854.9 EDN09865.1 - 0.48 10.3 0.0 0.48 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF624 DDE_1 PF03184.14 EDN09867.1 - 9.9e-10 37.9 0.0 1.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease ARID PF01388.16 EDN09867.1 - 8.2e-06 25.5 0.0 2.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain AAA_27 PF13514.1 EDN09867.1 - 0.061 11.0 0.7 0.082 10.5 0.5 1.1 1 0 0 1 1 1 0 AAA domain DDE_1 PF03184.14 EDN09868.1 - 2.2e-51 174.0 0.0 6.8e-51 172.4 0.0 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN09868.1 - 3.7e-09 35.9 0.1 8.5e-09 34.8 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN09868.1 - 1.7e-08 34.1 0.1 6e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.1 EDN09868.1 - 0.0054 16.7 0.1 0.017 15.1 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain zf-CCHC_4 PF14392.1 EDN09868.1 - 0.04 13.5 0.5 0.04 13.5 0.3 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EDN09868.1 - 0.05 13.2 0.4 0.45 10.2 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle NUMOD1 PF07453.8 EDN09868.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 NUMOD1 domain zf-CCHC PF00098.18 EDN09868.1 - 0.27 11.2 1.0 0.48 10.4 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Zn_clus PF00172.13 EDN09870.1 - 7.5e-10 38.5 10.4 1.2e-09 37.9 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BNIP3 PF06553.7 EDN09870.1 - 0.54 9.6 9.0 1.3 8.3 6.3 1.7 1 0 0 1 1 1 0 BNIP3 BAF1_ABF1 PF04684.8 EDN09870.1 - 0.55 9.0 22.4 0.92 8.2 15.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.9 EDN09870.1 - 0.89 9.2 15.8 2.1 7.9 11.0 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RVT_1 PF00078.22 EDN09871.1 - 6.9e-22 77.8 0.0 1.5e-19 70.2 0.0 2.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN09871.1 - 5.6e-15 55.0 0.2 3.6e-14 52.3 0.0 2.6 3 0 0 3 3 3 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN09871.1 - 0.00039 20.4 0.1 0.0013 18.7 0.0 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.19 EDN09872.1 - 3.3e-14 53.3 0.0 5.2e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 RNase H Copper-fist PF00649.13 EDN09873.1 - 5.7e-22 76.6 2.0 5.7e-22 76.6 1.4 3.0 2 1 1 3 3 3 1 Copper fist DNA binding domain PEX11 PF05648.9 EDN09874.1 - 1.7e-76 256.4 0.4 1.9e-76 256.2 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Sugar_tr PF00083.19 EDN09875.1 - 1.6e-27 96.2 31.6 1.4e-19 70.0 4.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDN09875.1 - 8.2e-16 57.6 36.4 1.3e-15 56.9 25.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Aminotran_1_2 PF00155.16 EDN09876.1 - 6.4e-43 147.0 0.0 9e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RPN7 PF10602.4 EDN09877.1 - 5.2e-55 185.5 1.0 8e-55 184.9 0.7 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EDN09877.1 - 1.8e-13 50.6 0.0 3.4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 EDN09877.1 - 0.017 14.9 2.2 0.043 13.6 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDN09877.1 - 0.19 12.4 3.9 0.14 12.8 0.8 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PEPCK_ATP PF01293.15 EDN09878.1 - 3.6e-209 695.0 0.0 4.3e-209 694.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_25 PF13481.1 EDN09878.1 - 0.026 13.9 0.0 0.061 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDN09878.1 - 0.041 14.1 0.0 10 6.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EDN09878.1 - 0.095 12.5 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EDN09878.1 - 0.16 11.8 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Mito_carr PF00153.22 EDN09881.1 - 8.7e-56 185.6 3.1 1.2e-20 73.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3611 PF12263.3 EDN09881.1 - 0.055 12.8 0.1 0.099 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) zf-Nse PF11789.3 EDN09885.1 - 4e-22 77.4 0.8 6.9e-22 76.7 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EDN09885.1 - 0.02 14.5 0.1 0.02 14.5 0.0 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.1 EDN09885.1 - 0.034 13.9 0.8 0.061 13.1 0.6 1.5 1 0 0 1 1 1 0 Ring finger domain zf-MIZ PF02891.15 EDN09885.1 - 2.1 7.9 9.2 0.11 11.9 0.9 2.4 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger Pox_MCEL PF03291.11 EDN09886.1 - 3e-61 207.1 0.0 8.4e-42 143.2 0.0 3.6 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 EDN09886.1 - 1.2e-08 35.3 0.0 3.4e-07 30.6 0.0 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN09886.1 - 8.6e-08 32.7 0.0 2.3e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN09886.1 - 1.5e-07 31.8 0.0 0.019 15.4 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EDN09886.1 - 6.3e-06 25.9 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN09886.1 - 8.7e-06 26.0 0.0 4.7e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN09886.1 - 6e-05 22.6 0.0 0.0033 17.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EDN09886.1 - 0.00019 20.5 0.0 0.00031 19.7 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Rsm1 PF08600.5 EDN09887.1 - 2e-30 104.4 0.0 5e-30 103.2 0.0 1.7 1 0 0 1 1 1 1 Rsm1-like zf-C3HC PF07967.8 EDN09887.1 - 1.7e-22 79.6 0.2 2.6e-18 66.0 0.0 3.4 2 1 1 3 3 3 3 C3HC zinc finger-like Med3 PF11593.3 EDN09887.1 - 0.17 11.0 5.2 0.31 10.2 3.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-CHY PF05495.7 EDN09888.1 - 1.8e-18 66.4 24.5 3.4e-18 65.5 9.0 3.4 3 1 0 3 3 3 2 CHY zinc finger DZR PF12773.2 EDN09888.1 - 2.2 8.1 17.2 4.2 7.2 0.3 3.7 3 1 0 3 3 3 0 Double zinc ribbon Cytochrome_C7 PF14522.1 EDN09888.1 - 7.2 6.3 20.1 0.4 10.3 3.0 3.6 2 1 0 2 2 2 0 Cytochrome c7 DUF3295 PF11702.3 EDN09891.1 - 2.3e-132 442.5 35.4 2.7e-132 442.3 24.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) HGTP_anticodon2 PF12745.2 EDN09891.1 - 2.5 7.1 12.5 0.45 9.6 1.7 2.5 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs LtrA PF06772.6 EDN09893.1 - 1.6e-11 43.7 16.5 1.6e-11 43.7 11.5 1.5 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) DUF1772 PF08592.6 EDN09893.1 - 0.17 11.6 6.4 0.18 11.5 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Cpn60_TCP1 PF00118.19 EDN09894.1 - 6.2e-149 496.7 2.5 7.1e-149 496.5 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.7 EDN09894.1 - 0.043 13.4 0.5 4.7 6.7 0.0 3.0 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein RVT_2 PF07727.9 EDN09895.1 - 1.4e-52 178.1 0.0 2e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN09895.1 - 3.2e-16 59.5 0.0 8.6e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN09895.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 GAG-pre-integrase domain DUF4219 PF13961.1 EDN09896.1 - 0.0046 16.3 0.2 0.013 14.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) zf-CCHC PF00098.18 EDN09896.1 - 1.5 8.8 4.3 2.5 8.1 3.0 1.4 1 0 0 1 1 1 0 Zinc knuckle Chromo_shadow PF01393.14 EDN09897.1 - 8.2e-14 51.1 0.1 2.6e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.19 EDN09897.1 - 3.8e-11 42.4 1.2 4.5e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Myb_DNA-bind_2 PF08914.6 EDN09898.1 - 2.8e-08 33.4 0.1 9.7e-08 31.7 0.0 2.0 1 1 1 2 2 2 1 Rap1 Myb domain Rap1_C PF11626.3 EDN09898.1 - 0.00093 19.0 0.1 0.0069 16.2 0.0 2.3 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-DHHC PF01529.15 EDN09900.1 - 0.014 14.7 0.1 0.019 14.3 0.1 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Atx10homo_assoc PF09759.4 EDN09901.1 - 1.1e-30 105.3 1.3 2.8e-30 104.0 0.2 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain zf-RING_2 PF13639.1 EDN09902.1 - 5e-08 32.6 2.2 8.4e-08 31.9 1.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDN09902.1 - 0.00012 22.0 0.5 0.0003 20.8 0.3 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EDN09902.1 - 0.0017 18.3 1.5 0.003 17.5 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDN09902.1 - 0.013 15.3 0.3 0.02 14.7 0.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FAD_binding_6 PF00970.19 EDN09903.1 - 8.4e-05 22.6 0.0 0.0046 17.0 0.0 2.7 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain Pyridox_oxidase PF01243.15 EDN09903.1 - 0.00042 20.2 0.0 0.82 9.7 0.0 2.5 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase LCE PF14672.1 EDN09905.1 - 0.043 14.2 18.5 0.72 10.3 2.4 2.3 2 0 0 2 2 2 0 Late cornified envelope Squash PF00299.13 EDN09905.1 - 0.066 13.0 15.8 1 9.2 2.8 2.4 2 0 0 2 2 2 0 Squash family serine protease inhibitor Nodulin_late PF07127.6 EDN09905.1 - 0.066 13.3 8.2 0.27 11.4 0.6 2.2 2 0 0 2 2 2 0 Late nodulin protein Gamma-thionin PF00304.15 EDN09905.1 - 0.78 9.8 18.9 3.4 7.7 3.9 2.5 2 0 0 2 2 2 0 Gamma-thionin family Colipase-like PF15083.1 EDN09905.1 - 0.93 9.4 4.0 12 5.8 0.1 2.1 2 0 0 2 2 2 0 Colipase-like Bys1 PF04681.7 EDN09906.1 - 1.4e-16 60.6 0.0 1.7e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein NTP_transferase PF00483.18 EDN09908.1 - 3.4e-20 72.3 0.0 5.8e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EDN09908.1 - 4.2e-09 35.5 9.3 6.5e-07 28.5 0.2 3.9 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EDN09908.1 - 0.00036 20.6 0.0 0.00062 19.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 EDN09908.1 - 0.0062 15.1 0.1 1.2 7.6 0.0 2.2 2 0 0 2 2 2 2 L-fucokinase Glycos_transf_2 PF00535.21 EDN09908.1 - 0.0073 16.0 0.0 0.015 15.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Hexapep_2 PF14602.1 EDN09908.1 - 0.039 13.5 2.7 0.11 12.1 0.0 2.6 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase Glyco_tranf_2_3 PF13641.1 EDN09908.1 - 0.092 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF2968 PF11180.3 EDN09908.1 - 0.14 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Dynamin_N PF00350.18 EDN09909.1 - 1.2e-22 80.5 0.0 3.5e-22 78.9 0.0 1.9 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EDN09909.1 - 1e-17 63.8 0.2 9.3e-15 54.1 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EDN09909.1 - 0.0033 17.2 2.4 0.34 10.8 1.7 2.7 1 1 0 1 1 1 1 Dynamin GTPase effector domain Miro PF08477.8 EDN09909.1 - 0.0073 16.7 0.0 0.024 15.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDN09909.1 - 0.0078 16.1 0.1 0.12 12.3 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.8 EDN09909.1 - 0.013 14.3 0.1 0.74 8.5 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) S-AdoMet_synt_C PF02773.11 EDN09909.1 - 0.1 12.3 0.0 0.32 10.7 0.0 1.8 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, C-terminal domain tRNA-synt_2 PF00152.15 EDN09910.1 - 1.2e-91 307.0 1.1 1.6e-91 306.6 0.8 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDN09910.1 - 2.1e-12 46.7 0.1 5.4e-11 42.2 0.0 2.8 2 1 0 3 3 3 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EDN09910.1 - 9.2e-06 25.0 0.0 0.011 14.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EDN09910.1 - 0.026 14.1 0.2 0.34 10.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) zf-RanBP PF00641.13 EDN09911.1 - 0.0078 15.3 5.5 0.026 13.6 3.8 2.0 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-B_box PF00643.19 EDN09911.1 - 0.032 14.1 4.9 0.07 13.0 3.4 1.5 1 0 0 1 1 1 0 B-box zinc finger Prok-RING_2 PF14445.1 EDN09911.1 - 0.2 11.6 4.9 0.51 10.3 3.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Spt5_N PF11942.3 EDN09911.1 - 0.92 10.1 10.2 0.25 11.9 4.6 2.0 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal IFT57 PF10498.4 EDN09911.1 - 1.2 7.8 5.6 1.7 7.3 3.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 zf-RING_4 PF14570.1 EDN09911.1 - 1.4 8.6 12.5 0.036 13.6 3.3 2.3 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain COX15-CtaA PF02628.10 EDN09912.1 - 1.1e-94 316.6 5.5 1.4e-94 316.4 3.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein BTB PF00651.26 EDN09913.1 - 0.00032 20.6 0.0 0.00071 19.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Zn_clus PF00172.13 EDN09914.1 - 2.8e-06 27.1 8.7 6.1e-06 26.0 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EDN09915.1 - 1.9e-25 89.6 0.4 2.7e-25 89.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN09915.1 - 2.1e-14 53.5 0.1 3.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EDN09915.1 - 1.1e-11 45.0 0.0 1.3e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EDN09915.1 - 9.2e-06 25.2 0.0 2.7e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EDN09915.1 - 4.7e-05 22.4 0.0 6.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EDN09915.1 - 0.0014 18.6 0.7 0.0043 17.0 0.5 1.7 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EDN09915.1 - 0.02 14.6 0.6 0.043 13.5 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 EDN09915.1 - 0.076 11.7 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 EDN09915.1 - 0.12 11.9 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyoxalase PF00903.20 EDN09916.1 - 3e-24 85.4 1.8 3.4e-16 59.3 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EDN09916.1 - 4.2e-17 62.1 0.6 1.9e-08 34.3 0.2 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EDN09916.1 - 9.6e-13 48.6 0.1 2.1e-06 28.2 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EDN09916.1 - 2.2e-07 30.9 0.1 0.0046 16.8 0.2 3.0 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EDN09916.1 - 4.3e-05 23.4 0.3 0.0014 18.6 0.2 2.5 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF4611 PF15387.1 EDN09917.1 - 0.19 11.8 1.1 0.52 10.5 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) HgmA PF04209.8 EDN09918.1 - 1.6e-187 623.0 0.0 1.9e-187 622.9 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAD_binding_3 PF01494.14 EDN09919.1 - 3.5e-13 49.3 0.0 9.4e-13 47.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EDN09919.1 - 0.00016 22.0 0.2 2.1 8.8 0.0 4.1 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDN09919.1 - 0.0017 17.3 2.5 0.31 9.8 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDN09919.1 - 0.027 13.3 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EDN09919.1 - 0.06 13.2 0.1 1.3 8.8 0.0 2.8 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN09919.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Oxidored_FMN PF00724.15 EDN09920.1 - 4e-66 223.3 0.0 5e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EDN09920.1 - 0.15 10.9 0.1 0.98 8.1 0.0 2.0 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) BATS PF06968.8 EDN09922.1 - 3.5e-30 103.6 0.2 4e-29 100.3 0.0 2.4 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EDN09922.1 - 1.6e-15 57.6 0.0 4.2e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Aminotran_3 PF00202.16 EDN09923.1 - 5.1e-36 124.2 0.0 2.2e-18 66.2 0.0 3.2 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EDN09923.1 - 6.1e-19 68.4 0.0 4.7e-11 42.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain Aminotran_1_2 PF00155.16 EDN09924.1 - 1.3e-34 119.7 0.0 1.5e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 EDN09924.1 - 5e-05 22.3 0.0 8.9e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-III Cys_Met_Meta_PP PF01053.15 EDN09924.1 - 0.0011 17.3 0.0 0.0015 16.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EDN09924.1 - 0.0087 14.8 0.0 0.044 12.5 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Tht1 PF04163.7 EDN09925.1 - 2e-09 36.4 0.2 5.2e-09 35.0 0.1 1.6 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein SPT16 PF08644.6 EDN09925.1 - 0.86 9.4 3.6 1.2 8.9 0.8 2.1 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) Ribosomal_L6 PF00347.18 EDN09926.1 - 1.8e-24 86.0 0.1 3.7e-14 52.9 0.0 2.6 3 0 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.20 EDN09927.1 - 2.1e-34 119.0 0.4 2.2e-33 115.7 0.3 2.3 1 1 0 1 1 1 1 Inositol monophosphatase family VHS PF00790.14 EDN09928.1 - 8.7e-18 64.3 0.0 1.9e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EDN09928.1 - 5.1e-12 45.6 1.2 1.3e-11 44.3 0.8 1.7 1 0 0 1 1 1 1 GAT domain PTS_IIA PF02255.11 EDN09928.1 - 0.064 13.1 0.1 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit DEAD PF00270.24 EDN09929.1 - 5.5e-44 149.6 0.0 1.3e-43 148.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN09929.1 - 1.1e-21 76.4 0.0 6.2e-21 74.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDN09929.1 - 0.0029 16.4 0.0 0.0043 15.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EDN09929.1 - 0.026 14.6 0.2 0.08 13.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain FtsJ PF01728.14 EDN09930.1 - 3.1e-62 209.7 0.0 3.7e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase FAD_binding_1 PF00667.15 EDN09931.1 - 1.4e-61 207.7 0.0 2.1e-61 207.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EDN09931.1 - 4.2e-11 43.3 0.0 1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 EDN09931.1 - 8.2e-08 32.3 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EDN09931.1 - 0.00032 20.6 0.1 0.00076 19.4 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain HMGL-like PF00682.14 EDN09935.1 - 3e-12 46.7 0.1 6.9e-12 45.5 0.0 1.5 2 0 0 2 2 2 1 HMGL-like Proteasome PF00227.21 EDN09936.1 - 2.5e-59 199.7 0.1 3.1e-59 199.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDN09936.1 - 3.3e-14 51.8 0.2 6.9e-14 50.8 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EDN09936.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit FF PF01846.14 EDN09937.1 - 9.3e-13 47.9 10.4 1.3e-08 34.6 0.2 3.5 3 0 0 3 3 3 3 FF domain TFIIS_M PF07500.9 EDN09939.1 - 2.4e-23 82.3 0.1 2.4e-23 82.3 0.1 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EDN09939.1 - 2.8e-18 66.4 0.0 5.2e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EDN09939.1 - 1.4e-10 40.7 12.5 2.4e-10 39.9 8.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 EDN09939.1 - 0.0076 16.4 6.8 0.039 14.2 4.7 2.3 1 1 0 1 1 1 1 PHD domain of transcriptional enhancer, Asx Terminase_GpA PF05876.7 EDN09939.1 - 0.031 12.6 7.0 0.051 11.9 4.8 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) PHD_2 PF13831.1 EDN09939.1 - 0.082 12.2 4.5 0.14 11.5 3.1 1.4 1 0 0 1 1 1 0 PHD-finger LUC7 PF03194.10 EDN09940.1 - 2.6e-73 246.6 0.2 3.2e-73 246.3 0.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus MCPsignal PF00015.16 EDN09940.1 - 0.0083 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3735 PF12537.3 EDN09940.1 - 0.056 13.5 0.1 3.6 7.7 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3735) DASH_Duo1 PF08651.5 EDN09940.1 - 0.11 12.0 0.1 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Duo1 GRP PF07172.6 EDN09940.1 - 9.4 6.7 19.7 18 5.8 13.7 1.5 1 0 0 1 1 1 0 Glycine rich protein family Gpi16 PF04113.9 EDN09941.1 - 2e-238 792.0 0.0 2.5e-238 791.7 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component vMSA PF00695.14 EDN09942.1 - 1.7 7.7 6.9 3.8 6.6 4.8 1.5 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus HECT PF00632.20 EDN09943.1 - 2e-84 283.4 0.0 4.1e-84 282.4 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CLASP_N PF12348.3 EDN09943.1 - 0.034 13.5 0.7 0.72 9.1 0.0 2.6 3 0 0 3 3 3 0 CLASP N terminal HEAT PF02985.17 EDN09943.1 - 0.078 13.0 0.6 2.8 8.2 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat Clr5 PF14420.1 EDN09943.1 - 0.15 11.9 0.2 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 Clr5 domain Arm PF00514.18 EDN09943.1 - 0.67 9.8 7.9 6.6 6.7 0.1 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Plasmodium_Vir PF05795.6 EDN09943.1 - 7 5.7 5.7 0.93 8.6 0.2 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein TFIIA PF03153.8 EDN09943.1 - 7 6.4 43.6 0.021 14.7 3.7 3.3 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit CTP_transf_2 PF01467.21 EDN09944.1 - 3e-26 92.3 0.0 3.9e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase HAD PF12710.2 EDN09945.1 - 8.8e-10 39.0 0.0 1.2e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EDN09945.1 - 0.00028 20.2 0.0 0.0014 18.0 0.0 2.0 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.7 EDN09945.1 - 0.0022 17.1 0.1 0.17 11.0 0.1 2.1 2 0 0 2 2 2 2 Putative Phosphatase HAD_2 PF13419.1 EDN09945.1 - 0.0039 17.4 0.0 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF2357 PF09823.4 EDN09945.1 - 0.062 12.3 0.0 0.085 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) TFR_dimer PF04253.10 EDN09946.1 - 2.3e-18 65.9 0.0 4.1e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EDN09946.1 - 1.8e-12 47.3 0.0 3.3e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EDN09946.1 - 0.00011 21.8 0.2 0.00067 19.3 0.0 2.2 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.10 EDN09946.1 - 0.00023 20.5 0.0 0.00038 19.7 0.0 1.3 1 0 0 1 1 1 1 Nicastrin SIS PF01380.17 EDN09948.1 - 4.8e-12 45.6 0.0 1.2e-11 44.3 0.0 1.7 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EDN09948.1 - 1.5e-05 24.7 0.0 4.2e-05 23.2 0.0 1.7 1 1 1 2 2 2 1 SIS domain Ubie_methyltran PF01209.13 EDN09949.1 - 2.1e-80 269.2 0.0 2.6e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EDN09949.1 - 3.6e-16 59.1 0.0 5.1e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN09949.1 - 1.5e-13 51.0 0.0 3.8e-13 49.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN09949.1 - 1.7e-10 40.8 0.0 2.7e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN09949.1 - 8.9e-10 38.8 0.0 1.8e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN09949.1 - 1e-09 38.7 0.0 1.9e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN09949.1 - 7.3e-09 36.2 0.0 1.3e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN09949.1 - 0.00042 20.3 0.0 0.00094 19.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EDN09949.1 - 0.039 13.5 0.0 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_24 PF13578.1 EDN09949.1 - 0.1 13.4 0.0 0.21 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.3 EDN09951.1 - 1.8e-39 135.4 0.0 2.6e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN09951.1 - 5.9e-09 35.6 7.9 1.2e-08 34.7 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.18 EDN09954.1 - 7.2e-10 39.2 0.1 9.1e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EDN09954.1 - 0.0082 15.7 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Nucleoplasmin PF03066.10 EDN09955.1 - 0.037 13.5 6.1 0.066 12.7 4.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 EDN09955.1 - 0.13 10.7 7.0 0.11 10.9 4.8 1.1 1 0 0 1 1 1 0 Daxx Family FAM176 PF14851.1 EDN09955.1 - 0.37 10.4 3.3 0.55 9.8 2.3 1.3 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.8 EDN09955.1 - 0.58 9.7 6.5 0.96 9.0 4.5 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 EDN09955.1 - 0.82 9.4 4.6 1.3 8.8 3.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal BSP_II PF05432.6 EDN09955.1 - 0.92 8.7 11.1 1.4 8.1 7.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NESP55 PF06390.7 EDN09955.1 - 1.1 8.6 21.7 0.14 11.4 2.1 2.1 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) PBP1_TM PF14812.1 EDN09955.1 - 1.1 9.6 6.4 2.7 8.3 4.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal VID27 PF08553.5 EDN09955.1 - 1.1 7.3 4.2 1.2 7.2 2.9 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein CobT PF06213.7 EDN09955.1 - 1.6 7.7 8.3 2.3 7.2 5.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nucleo_P87 PF07267.6 EDN09955.1 - 1.7 7.2 7.3 2.2 6.8 5.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3682 PF12446.3 EDN09955.1 - 5.2 7.3 12.4 0.19 12.0 4.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) E1_dh PF00676.15 EDN09958.1 - 1.1e-85 287.0 0.0 1.3e-85 286.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EDN09958.1 - 0.00027 20.5 0.1 0.0024 17.4 0.0 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.5 EDN09958.1 - 0.0061 15.1 0.0 0.01 14.4 0.0 1.3 1 0 0 1 1 1 1 XFP N-terminal domain DUF1470 PF07336.6 EDN09958.1 - 0.072 13.4 0.2 0.2 11.9 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1470) DXP_synthase_N PF13292.1 EDN09958.1 - 0.15 10.9 0.0 0.46 9.3 0.0 1.7 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase FlaC_arch PF05377.6 EDN09959.1 - 0.18 11.7 2.6 0.36 10.7 1.8 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Complex1_30kDa PF00329.14 EDN09961.1 - 2e-33 114.6 0.0 3e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Fungal_trans PF04082.13 EDN09962.1 - 5.8e-25 87.6 0.1 1.1e-24 86.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN09962.1 - 3.7e-06 26.7 10.1 7e-06 25.8 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BUD22 PF09073.5 EDN09963.1 - 9.4e-52 176.5 18.5 1.1e-51 176.2 12.8 1.0 1 0 0 1 1 1 1 BUD22 Reo_sigmaC PF04582.7 EDN09964.1 - 1.1 8.4 10.7 4.6 6.3 0.2 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EDN09964.1 - 3.9 7.2 21.1 3.7 7.3 0.1 4.3 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tn7_Tnp_TnsA_C PF08721.6 EDN09964.1 - 4.1 7.5 7.1 3.3 7.7 0.1 3.8 4 0 0 4 4 4 0 TnsA endonuclease C terminal DUF768 PF05589.6 EDN09964.1 - 8.8 6.3 10.4 11 6.0 0.1 4.5 5 0 0 5 5 5 0 Protein of unknown function (DUF768) PNP_UDP_1 PF01048.15 EDN09965.1 - 3.6e-37 127.5 0.2 4.3e-37 127.3 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Glyco_hydro_3 PF00933.16 EDN09966.1 - 6.4e-90 301.1 0.0 9.1e-90 300.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EDN09966.1 - 8e-53 179.2 0.0 8.2e-52 175.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EDN09966.1 - 1.6e-18 66.4 0.4 3.1e-18 65.4 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF572 PF04502.8 EDN09967.1 - 6.5e-52 176.7 0.0 8.1e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) B_lectin PF01453.19 EDN09967.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 D-mannose binding lectin PTPA PF03095.10 EDN09968.1 - 1.3e-103 346.2 0.0 5e-103 344.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Myb_DNA-binding PF00249.26 EDN09969.1 - 0.008 16.2 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Tropomyosin_1 PF12718.2 EDN09971.1 - 7.6e-06 25.8 15.1 7.6e-06 25.8 10.5 9.8 1 1 8 9 9 9 2 Tropomyosin like Filament PF00038.16 EDN09971.1 - 0.00069 19.1 20.0 0.00069 19.1 13.9 7.0 1 1 5 6 6 6 4 Intermediate filament protein Fib_alpha PF08702.5 EDN09971.1 - 0.0046 17.0 3.2 0.0046 17.0 2.2 8.3 2 1 4 8 8 8 4 Fibrinogen alpha/beta chain family Rad4 PF03835.10 EDN09972.1 - 3.6e-36 123.7 0.1 6.6e-36 122.8 0.1 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EDN09972.1 - 5.2e-25 86.9 0.1 1.1e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EDN09972.1 - 6.9e-21 73.5 0.1 1.8e-20 72.2 0.1 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EDN09972.1 - 1.7e-13 50.6 1.6 3.2e-13 49.7 0.0 2.4 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EDN09972.1 - 0.0026 17.9 0.2 0.014 15.5 0.0 2.4 2 1 0 2 2 2 1 Transglutaminase-like superfamily BSD PF03909.12 EDN09973.1 - 3.5e-13 49.0 0.5 7.9e-13 47.9 0.3 1.7 1 0 0 1 1 1 1 BSD domain Ran-binding PF05508.6 EDN09974.1 - 1.5e-118 395.1 2.1 1.9e-118 394.7 1.4 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.22 EDN09975.1 - 5.9e-43 146.5 0.0 9e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDN09975.1 - 2e-19 69.5 0.0 5.2e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDN09975.1 - 1.1e-08 35.0 0.5 2.6e-08 33.8 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDN09975.1 - 0.0031 17.4 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EDN09975.1 - 0.0037 16.0 0.3 0.0063 15.2 0.2 1.3 1 0 0 1 1 1 1 G-protein alpha subunit TFIIF_alpha PF05793.7 EDN09975.1 - 1.3 7.3 7.4 2 6.6 5.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) WGG PF10273.4 EDN09976.1 - 4.1e-32 110.1 0.1 7.4e-32 109.2 0.0 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 NOA36 PF06524.7 EDN09976.1 - 0.033 13.4 3.8 0.048 12.9 2.6 1.2 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.6 EDN09976.1 - 0.15 9.8 4.4 0.23 9.2 3.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 EDN09976.1 - 0.16 9.9 1.3 0.21 9.5 0.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EDN09976.1 - 0.37 9.2 7.6 0.49 8.8 5.3 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EDN09976.1 - 0.88 7.4 9.4 1 7.1 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 EDN09976.1 - 2.3 7.2 5.2 3.7 6.6 3.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Abhydrolase_3 PF07859.8 EDN09978.1 - 3.7e-25 88.7 0.2 8.2e-16 58.2 0.0 2.9 3 1 0 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EDN09978.1 - 1.1e-12 47.2 0.0 2.6e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EDN09978.1 - 0.026 14.2 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDN09978.1 - 0.19 10.8 0.9 1.2 8.2 0.0 2.5 3 1 1 4 4 4 0 Prolyl oligopeptidase family ParA PF10609.4 EDN09979.1 - 7.1e-32 109.1 0.0 1.4e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EDN09979.1 - 4.9e-10 39.1 0.0 7.5e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EDN09979.1 - 0.001 19.0 0.0 0.0038 17.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EDN09979.1 - 0.016 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ ArsA_ATPase PF02374.10 EDN09979.1 - 0.23 10.4 0.3 0.67 8.9 0.1 1.7 2 0 0 2 2 2 0 Anion-transporting ATPase TRAUB PF08164.7 EDN09980.1 - 1e-32 112.0 0.0 3e-32 110.5 0.0 1.9 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EDN09980.1 - 1.1e-32 112.9 0.8 1.1e-32 112.9 0.5 2.8 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor DUF4537 PF15057.1 EDN09981.1 - 0.0017 18.1 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) TUDOR PF00567.19 EDN09981.1 - 0.033 14.0 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Tudor domain FH2 PF02181.18 EDN09981.1 - 0.067 12.0 0.5 0.087 11.6 0.3 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain MDH PF02315.11 EDN09982.1 - 0.17 11.8 0.5 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit PAP1 PF08601.5 EDN09983.1 - 5e-62 210.6 9.5 1.3e-58 199.3 1.0 2.6 2 1 1 3 3 3 2 Transcription factor PAP1 bZIP_1 PF00170.16 EDN09983.1 - 4.8e-09 36.0 11.2 1e-08 34.9 7.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor IncA PF04156.9 EDN09983.1 - 0.0015 18.1 1.6 0.0028 17.2 1.1 1.3 1 0 0 1 1 1 1 IncA protein DUF16 PF01519.11 EDN09983.1 - 0.0078 16.4 1.4 0.022 14.9 1.0 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF16 Bacillus_HBL PF05791.6 EDN09983.1 - 0.0084 15.5 1.0 0.014 14.7 0.7 1.3 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) bZIP_2 PF07716.10 EDN09983.1 - 0.016 15.0 15.5 0.2 11.5 10.8 2.4 1 1 0 1 1 1 0 Basic region leucine zipper Adeno_PIX PF03955.9 EDN09983.1 - 0.029 14.8 0.8 0.073 13.5 0.6 1.7 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) bZIP_Maf PF03131.12 EDN09983.1 - 0.051 13.8 10.0 0.12 12.7 7.0 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor PilJ PF13675.1 EDN09983.1 - 0.1 12.9 1.4 0.26 11.6 0.4 1.9 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term FlaC_arch PF05377.6 EDN09983.1 - 0.27 11.1 2.1 0.59 10.0 1.4 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) EMP24_GP25L PF01105.19 EDN09983.1 - 3.1 7.4 5.3 0.34 10.6 0.5 1.7 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2433 PF10360.4 EDN09984.1 - 2e-40 138.1 0.0 3.6e-40 137.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 EDN09984.1 - 0.0045 16.8 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EDN09984.1 - 0.011 15.2 0.0 0.021 14.2 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Peptidase_M35 PF02102.10 EDN09985.1 - 6.8e-79 265.1 8.3 8.9e-79 264.7 5.8 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EDN09985.1 - 5.2e-09 36.7 1.5 9.2e-09 35.9 0.6 1.8 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EDN09985.1 - 0.0041 16.5 4.4 0.011 15.1 3.1 1.6 1 1 0 1 1 1 1 Putative peptidase family Lumazine_bd PF12870.2 EDN09985.1 - 0.036 14.1 0.2 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Lumazine-binding domain Patched PF02460.13 EDN09986.1 - 6e-75 252.7 10.5 3.7e-74 250.0 7.3 1.9 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EDN09986.1 - 2.1e-51 173.3 4.3 2.1e-51 173.3 3.0 2.9 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EDN09986.1 - 3.2e-07 29.3 8.1 3.2e-07 29.3 5.6 3.2 3 0 0 3 3 3 2 MMPL family Folate_rec PF03024.9 EDN09986.1 - 0.021 14.4 2.2 0.044 13.4 1.5 1.5 1 0 0 1 1 1 0 Folate receptor family HEAT_2 PF13646.1 EDN09987.1 - 5.2e-24 84.3 3.8 8.9e-07 29.1 0.0 7.9 6 2 1 7 7 6 4 HEAT repeats HEAT PF02985.17 EDN09987.1 - 1.1e-22 77.9 2.8 4.6e-05 23.1 0.0 10.2 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 EDN09987.1 - 6.6e-18 64.6 17.4 5.3e-05 23.5 0.0 11.3 12 3 3 15 15 13 5 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EDN09987.1 - 1e-10 41.8 0.7 1.8 9.0 0.0 7.5 7 2 2 9 9 8 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EDN09987.1 - 4.8e-08 32.8 2.0 6.9e-07 29.0 0.1 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.2 EDN09987.1 - 6.2e-07 29.4 1.6 0.41 10.4 0.5 4.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EDN09987.1 - 6.4e-05 22.4 0.0 0.49 9.7 0.0 3.8 3 1 1 4 4 4 2 CLASP N terminal ParcG PF10274.4 EDN09987.1 - 8.8e-05 22.4 0.2 0.1 12.4 0.1 3.4 3 1 0 3 3 3 1 Parkin co-regulated protein MMS19_C PF12460.3 EDN09987.1 - 0.00028 19.7 1.9 0.067 11.9 0.0 4.2 3 3 1 4 4 4 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 EDN09987.1 - 0.0038 15.6 0.1 7.9 4.6 0.0 4.1 2 2 2 4 4 4 1 Adaptin N terminal region UNC45-central PF11701.3 EDN09987.1 - 0.013 15.1 1.5 0.13 11.8 0.3 3.3 2 1 2 4 4 4 0 Myosin-binding striated muscle assembly central Arm PF00514.18 EDN09987.1 - 0.017 14.9 0.1 34 4.4 0.0 4.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Ipi1_N PF12333.3 EDN09987.1 - 0.024 14.5 0.3 12 5.8 0.1 4.3 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation PUL PF08324.6 EDN09987.1 - 0.06 12.1 0.0 0.17 10.6 0.0 1.7 1 0 0 1 1 1 0 PUL domain Bacillus_HBL PF05791.6 EDN09987.1 - 0.12 11.7 0.1 0.34 10.2 0.0 1.8 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) ADH_zinc_N_2 PF13602.1 EDN09988.1 - 1.5e-13 51.7 0.0 3.5e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EDN09988.1 - 4.2e-10 39.2 0.0 8.6e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Abhydrolase_3 PF07859.8 EDN09989.1 - 6.7e-21 74.8 1.6 2.6e-20 72.9 1.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EDN09989.1 - 7.6e-11 41.2 0.0 3.4e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EDN09989.1 - 0.063 13.0 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 EDN09989.1 - 0.11 11.2 0.4 5.9 5.4 0.1 2.1 2 0 0 2 2 2 0 Carboxylesterase family UPF1_Zn_bind PF09416.5 EDN09990.1 - 0.064 12.8 0.6 0.079 12.5 0.4 1.3 1 1 0 1 1 1 0 RNA helicase (UPF2 interacting domain) COesterase PF00135.23 EDN09992.1 - 1.6e-73 248.2 0.1 7.5e-58 196.5 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EDN09992.1 - 0.045 13.3 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold F-actin_cap_A PF01267.12 EDN09993.1 - 7.9e-75 251.3 0.0 2.7e-41 141.4 0.0 2.0 1 1 1 2 2 2 2 F-actin capping protein alpha subunit ELO PF01151.13 EDN09995.1 - 6.8e-10 38.6 14.5 1e-09 38.0 10.0 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family DAD PF02109.11 EDN09995.1 - 0.21 11.6 5.4 0.052 13.6 1.2 1.8 2 0 0 2 2 2 0 DAD family PAP2 PF01569.16 EDN09996.1 - 4.4e-23 81.3 1.6 4.4e-23 81.3 1.1 2.4 2 1 0 2 2 2 1 PAP2 superfamily NACHT PF05729.7 EDN09997.1 - 7.3e-06 25.7 0.0 1.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EDN09997.1 - 3e-05 24.1 0.3 0.00017 21.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EDN09997.1 - 0.0015 18.5 0.2 0.0043 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EDN09997.1 - 0.025 15.4 0.0 0.13 13.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EDN09997.1 - 0.064 12.9 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase DUF2075 PF09848.4 EDN09997.1 - 0.084 11.8 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Med7 PF05983.6 EDN09998.1 - 2.7e-59 199.5 0.7 3.7e-59 199.1 0.5 1.2 1 0 0 1 1 1 1 MED7 protein Prenyltransf PF01255.14 EDN09998.1 - 0.016 14.3 0.1 0.024 13.7 0.1 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase K_trans PF02705.11 EDN09999.1 - 5.3e-143 477.2 9.0 4.8e-82 276.0 1.2 2.1 1 1 1 2 2 2 2 K+ potassium transporter Cyt-b5 PF00173.23 EDN10000.1 - 1.6e-24 85.4 0.1 2.1e-24 85.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HATPase_c PF02518.21 EDN10000.1 - 0.04 13.6 0.3 0.099 12.3 0.2 1.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YqzH PF14164.1 EDN10000.1 - 0.13 12.1 0.2 0.28 11.1 0.1 1.5 1 0 0 1 1 1 0 YqzH-like protein GTP_EFTU PF00009.22 EDN10001.1 - 6.6e-49 165.8 0.0 1.2e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EDN10001.1 - 1.2e-21 76.5 2.0 2.3e-21 75.6 1.4 1.4 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 EDN10001.1 - 9.6e-07 28.7 0.0 2.9e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EDN10001.1 - 2.1e-06 27.7 0.0 1.1e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Miro PF08477.8 EDN10001.1 - 0.0012 19.2 0.0 0.0096 16.4 0.0 2.6 3 1 0 3 3 3 1 Miro-like protein Gtr1_RagA PF04670.7 EDN10001.1 - 0.002 17.2 0.0 0.0048 16.0 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EDN10001.1 - 0.037 13.2 0.0 5 6.3 0.0 2.5 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EDN10001.1 - 0.064 12.5 0.0 1.3 8.2 0.0 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B GTP_EFTU_D3 PF03143.12 EDN10001.1 - 0.079 13.1 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain G-alpha PF00503.15 EDN10001.1 - 0.15 10.6 0.5 0.34 9.5 0.3 1.5 1 0 0 1 1 1 0 G-protein alpha subunit HSP70 PF00012.15 EDN10002.1 - 3.1e-255 847.7 9.8 3.5e-255 847.5 6.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDN10002.1 - 9.6e-16 57.2 0.3 1.2e-14 53.7 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EDN10002.1 - 0.026 13.6 4.5 0.25 10.4 0.1 3.1 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DNase_NucA_NucB PF14040.1 EDN10003.1 - 2.8e-05 24.2 0.5 7e-05 22.9 0.3 1.7 1 1 0 1 1 1 1 Deoxyribonuclease NucA/NucB UCH PF00443.24 EDN10004.1 - 9.1e-59 198.7 0.0 1.4e-58 198.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDN10004.1 - 1.3e-25 90.4 0.0 2.4e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EDN10004.1 - 0.00057 20.2 0.0 0.0019 18.5 0.0 2.0 1 0 0 1 1 1 1 Rhodanese-like domain VHS PF00790.14 EDN10005.1 - 1.8e-40 137.8 0.0 3.2e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 VHS domain UIM PF02809.15 EDN10005.1 - 1.1e-05 24.5 7.5 0.01 15.3 1.0 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif TCO89 PF10452.4 EDN10005.1 - 3.3e-05 23.0 0.1 3.3e-05 23.0 0.0 3.4 5 0 0 5 5 5 2 TORC1 subunit TCO89 ESR1_C PF12743.2 EDN10006.1 - 0.12 11.9 1.6 0.25 10.8 1.1 1.5 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal RCC1 PF00415.13 EDN10007.1 - 2.3e-23 82.1 0.5 7.3e-08 32.5 0.0 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EDN10007.1 - 3.6e-15 55.9 0.0 1e-06 28.6 0.0 2.9 3 0 0 3 3 3 2 BTB/POZ domain Ank_4 PF13637.1 EDN10007.1 - 3.5e-10 40.1 0.2 6.5e-06 26.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RCC1_2 PF13540.1 EDN10007.1 - 3.1e-08 33.0 2.2 6.3e-08 32.0 0.3 2.6 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 EDN10007.1 - 1.2e-06 28.1 0.1 0.049 13.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EDN10007.1 - 8.1e-06 26.0 0.1 4.8e-05 23.6 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EDN10007.1 - 0.0011 18.6 0.0 0.043 13.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EDN10007.1 - 0.014 15.6 0.0 1.2 9.4 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) PAT1 PF09770.4 EDN10007.1 - 9.5 4.3 23.5 15 3.7 16.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATG13 PF10033.4 EDN10009.1 - 3.4e-77 259.0 0.0 7.6e-77 257.8 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein 13 NUC153 PF08159.7 EDN10013.1 - 3.5e-14 52.0 2.5 7.4e-14 51.0 1.7 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EDN10013.1 - 3e-06 26.8 0.2 0.087 12.7 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Med13_C PF06333.7 EDN10014.1 - 4.6e-118 394.4 0.0 4.6e-118 394.4 0.0 2.0 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EDN10014.1 - 5.9e-44 150.3 0.0 5.9e-44 150.3 0.0 2.0 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal Amidase PF01425.16 EDN10015.1 - 5.7e-21 74.8 0.1 8.7e-13 47.9 0.0 3.4 4 0 0 4 4 4 3 Amidase zf-NADH-PPase PF09297.6 EDN10016.1 - 0.013 14.9 0.1 1.8 8.1 0.1 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Ribosomal_S21e PF01249.13 EDN10016.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S21e Reo_sigmaC PF04582.7 EDN10017.1 - 6.8e-05 22.2 39.0 0.0044 16.2 1.4 5.0 2 2 3 5 5 5 5 Reovirus sigma C capsid protein WEMBL PF05701.6 EDN10017.1 - 1.1 7.6 92.6 0.1 11.0 1.6 4.3 1 1 2 3 3 3 0 Weak chloroplast movement under blue light Cellulase PF00150.13 EDN10019.1 - 1.1e-10 41.1 0.1 1.1e-10 41.1 0.1 3.4 4 1 1 6 6 6 2 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.20 EDN10020.1 - 4e-60 203.1 0.0 5.6e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN10020.1 - 5.6e-33 114.0 0.0 8.5e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN10020.1 - 3.3e-06 26.2 0.0 4.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN10020.1 - 0.0011 18.7 1.9 0.0018 18.0 0.2 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EDN10020.1 - 0.0094 15.0 0.2 0.021 13.8 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF605 PF04652.11 EDN10020.1 - 2.6 7.3 10.1 3.5 6.9 7.0 1.1 1 0 0 1 1 1 0 Vta1 like SNF2_N PF00176.18 EDN10022.1 - 1e-76 257.6 0.0 1.7e-76 256.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD_2 PF06733.10 EDN10022.1 - 0.003 16.9 0.0 0.0074 15.7 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 F-112 PF09645.5 EDN10022.1 - 0.019 14.8 3.5 0.37 10.6 0.0 3.5 4 0 0 4 4 4 0 F-112 protein SIR2 PF02146.12 EDN10023.1 - 2e-36 125.3 0.0 3.8e-24 85.3 0.0 2.0 2 0 0 2 2 2 2 Sir2 family Pyridox_ox_2 PF12900.2 EDN10024.1 - 2.8e-35 121.2 0.0 4.9e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.20 EDN10025.1 - 2.2e-12 46.7 0.0 2.3e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain FR47 PF08445.5 EDN10026.1 - 4.5e-05 23.1 0.0 0.00061 19.4 0.0 2.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.19 EDN10026.1 - 0.013 15.5 0.4 0.16 12.0 0.3 2.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EDN10026.1 - 0.035 14.2 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peptidase_M24 PF00557.19 EDN10027.1 - 1.3e-50 171.8 0.0 1.9e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EDN10027.1 - 8.5e-33 112.5 0.0 1.5e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.5 EDN10028.1 - 1.1e-43 147.9 0.0 2.6e-43 146.7 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EDN10028.1 - 2.1e-24 84.9 0.3 4e-24 84.0 0.2 1.5 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 EDN10028.1 - 0.0023 17.7 0.1 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EDN10028.1 - 0.019 15.1 0.0 0.057 13.5 0.0 1.9 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Zn_clus PF00172.13 EDN10029.1 - 3.7e-07 29.9 9.5 3.7e-07 29.9 6.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 EDN10029.1 - 0.011 16.0 3.4 0.011 16.0 2.4 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Pantoate_transf PF02548.10 EDN10030.1 - 2.8e-103 344.6 0.6 3.2e-103 344.3 0.4 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EDN10030.1 - 4.5e-08 32.6 1.4 1.1e-07 31.3 0.9 1.8 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PA PF02225.17 EDN10030.1 - 0.063 12.9 0.3 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 PA domain APG12 PF04110.8 EDN10031.1 - 6.1e-29 100.0 0.0 8.4e-29 99.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EDN10031.1 - 0.075 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like Glyco_hydro_16 PF00722.16 EDN10032.1 - 6.2e-38 129.9 2.2 1e-37 129.2 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Mucin PF01456.12 EDN10032.1 - 0.62 9.8 16.0 1.1 9.0 11.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Acyl-CoA_dh_1 PF00441.19 EDN10034.1 - 1.1e-31 109.9 0.8 1.5e-31 109.5 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDN10034.1 - 1.5e-20 72.4 0.8 3.1e-20 71.4 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EDN10034.1 - 2.1e-19 69.1 0.0 4.9e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 EDN10034.1 - 0.0002 21.6 0.0 0.001 19.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EDN10034.1 - 0.12 12.9 2.5 0.13 12.8 0.3 2.2 2 1 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Glyco_hydro_18 PF00704.23 EDN10035.1 - 1.5e-36 126.5 0.0 7.5e-27 94.6 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 DDE_1 PF03184.14 EDN10036.1 - 3.1e-40 137.6 0.0 3.7e-21 75.2 0.0 2.5 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN10036.1 - 3.2e-11 42.8 0.0 6.5e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN10036.1 - 2.5e-10 39.7 0.2 4.7e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EDN10036.1 - 0.064 13.2 0.1 0.36 10.8 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain DUF3038 PF11237.3 EDN10036.1 - 0.1 12.4 0.1 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) KRBA1 PF15287.1 EDN10037.1 - 2.3 7.6 7.3 0.32 10.3 0.3 2.1 1 1 1 2 2 2 0 KRBA1 family repeat DDE_Tnp_1_7 PF13843.1 EDN10038.1 - 5e-18 65.2 1.4 1.6e-09 37.2 0.2 2.1 1 1 1 2 2 2 2 Transposase IS4 Choline_kinase PF01633.15 EDN10039.1 - 0.026 14.1 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EDN10039.1 - 0.026 13.8 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EDN10039.1 - 0.033 13.9 0.2 0.033 13.9 0.1 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family MAP7 PF05672.6 EDN10039.1 - 1.2 8.4 42.0 2.9 7.2 29.1 1.5 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Myb_DNA-bind_6 PF13921.1 EDN10040.1 - 0.0008 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain RVT_1 PF00078.22 EDN10041.1 - 5.4e-22 78.2 0.0 1.3e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 EDN10041.1 - 0.0091 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EDN10041.1 - 0.038 13.9 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EDN10041.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDN10041.1 - 0.26 11.8 0.0 0.57 10.7 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease UQ_con PF00179.21 EDN10043.1 - 1.1e-27 96.2 0.0 1.5e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LAMTOR PF15454.1 EDN10044.1 - 1.8e-20 73.0 1.9 2.4e-20 72.5 0.0 1.9 1 1 1 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF2011 PF09428.5 EDN10046.1 - 4.6e-44 149.4 4.8 6.3e-44 149.0 3.3 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Trypan_PARP PF05887.6 EDN10048.1 - 8.6 6.1 24.0 34 4.2 0.0 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Cerato-platanin PF07249.7 EDN10049.1 - 9.8e-39 132.0 0.2 1.3e-38 131.6 0.1 1.1 1 0 0 1 1 1 1 Cerato-platanin Glyco_hydro_45 PF02015.11 EDN10049.1 - 0.041 13.9 0.1 0.044 13.8 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 MFS_1 PF07690.11 EDN10050.1 - 2.3e-46 158.1 44.3 5e-46 157.0 30.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN10050.1 - 4.7e-14 51.8 21.8 1e-13 50.6 8.6 3.8 1 1 2 4 4 4 3 Sugar (and other) transporter Flavoprotein PF02441.14 EDN10051.1 - 4.7e-06 26.3 0.0 8.4e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein Dimer_Tnp_hAT PF05699.9 EDN10051.1 - 4.7 6.9 8.4 28 4.4 0.0 4.4 3 2 1 4 4 4 0 hAT family C-terminal dimerisation region Asparaginase_2 PF01112.13 EDN10052.1 - 3.1e-28 98.4 10.5 5.9e-16 58.0 0.9 4.9 4 1 1 5 5 5 4 Asparaginase FA_synthesis PF02504.10 EDN10052.1 - 0.057 12.2 0.3 0.091 11.6 0.2 1.2 1 0 0 1 1 1 0 Fatty acid synthesis protein Tim17 PF02466.14 EDN10053.1 - 5.9e-34 116.8 7.6 6.6e-34 116.7 5.3 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Orbi_VP2 PF00898.12 EDN10054.1 - 0.2 9.1 0.0 0.28 8.6 0.0 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 Ank_2 PF12796.2 EDN10055.1 - 3.7e-33 113.7 0.1 1.1e-17 64.0 0.0 3.8 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EDN10055.1 - 5.7e-26 88.9 7.7 7.3e-06 25.5 0.1 7.0 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 EDN10055.1 - 3.6e-21 73.1 0.2 0.00034 20.5 0.0 6.8 6 1 1 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 EDN10055.1 - 3.7e-21 74.6 1.1 4.6e-09 36.2 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN10055.1 - 4.9e-21 74.6 0.2 1.3e-09 38.2 0.0 5.8 3 2 3 6 6 6 4 Ankyrin repeats (many copies) DUF1110 PF06533.7 EDN10055.1 - 0.028 14.2 1.1 2.6 7.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1110) Lipase_GDSL_2 PF13472.1 EDN10056.1 - 7e-11 42.5 0.0 1.1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EDN10056.1 - 0.0011 18.8 2.9 0.0058 16.4 2.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TraQ PF09679.5 EDN10057.1 - 0.018 14.9 0.1 0.078 12.9 0.0 1.9 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Peptidase_M20 PF01546.23 EDN10058.1 - 9.7e-24 83.9 0.0 4.7e-23 81.6 0.0 2.1 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EDN10058.1 - 9.2e-19 66.5 1.8 5.4e-05 22.9 0.0 6.1 5 1 0 5 5 5 4 WD domain, G-beta repeat M20_dimer PF07687.9 EDN10058.1 - 4.4e-05 23.1 0.0 8.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EDN10058.1 - 0.0029 17.3 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 EDN10058.1 - 0.055 12.2 0.0 0.16 10.7 0.0 1.6 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase PQQ_3 PF13570.1 EDN10058.1 - 3.8 7.9 7.9 20 5.6 0.0 4.8 6 0 0 6 6 6 0 PQQ-like domain DUF747 PF05346.6 EDN10059.1 - 3.2e-109 365.0 8.4 5.6e-109 364.2 5.8 1.4 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF202 PF02656.10 EDN10060.1 - 0.77 10.0 12.4 0.078 13.2 2.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF202) MFS_1 PF07690.11 EDN10061.1 - 1.7e-08 33.5 34.6 5.9e-05 21.9 11.8 3.7 3 1 1 4 4 4 3 Major Facilitator Superfamily TM_helix PF05552.7 EDN10061.1 - 0.41 10.3 5.2 0.095 12.3 0.3 2.5 2 0 0 2 2 2 0 Conserved TM helix AAA_13 PF13166.1 EDN10062.1 - 0.0019 16.7 43.8 0.014 13.8 7.7 3.4 1 1 2 3 3 3 2 AAA domain RPW8 PF05659.6 EDN10062.1 - 4.8 6.7 14.8 0.063 12.8 0.4 3.4 4 0 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF21 PF01595.15 EDN10063.1 - 2.5e-28 98.5 0.1 4e-28 97.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EDN10063.1 - 1.9e-07 30.7 0.5 0.015 15.0 0.0 2.7 2 0 0 2 2 2 2 CBS domain zf-C2H2_2 PF12756.2 EDN10064.1 - 1.4e-37 127.8 13.4 3.9e-29 100.7 3.8 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EDN10064.1 - 2.4e-11 43.4 11.8 2.3e-07 30.7 0.8 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDN10064.1 - 9.9e-08 31.9 8.1 3.3e-06 27.0 1.0 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EDN10064.1 - 0.002 17.9 8.8 0.072 13.0 0.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger DUF2024 PF09630.5 EDN10064.1 - 0.013 15.1 2.3 0.15 11.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) zf-C2H2 PF00096.21 EDN10064.1 - 0.094 13.1 0.5 0.094 13.1 0.4 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN10064.1 - 4 8.0 22.0 0.52 10.7 0.3 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger HECT PF00632.20 EDN10065.1 - 4.4e-74 249.4 0.0 7.4e-74 248.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) His_Phos_1 PF00300.17 EDN10066.1 - 2.1e-15 57.1 0.0 3.9e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pyr_redox_2 PF07992.9 EDN10068.1 - 6.2e-15 55.6 0.0 8.1e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDN10068.1 - 0.0017 18.4 0.0 0.45 10.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDN10068.1 - 0.006 15.6 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EDN10068.1 - 0.0089 15.1 0.1 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EDN10068.1 - 0.016 13.7 0.0 0.025 13.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 EDN10068.1 - 0.044 12.6 0.5 0.097 11.5 0.3 1.6 1 1 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.1 EDN10068.1 - 0.055 12.3 0.0 3.4 6.4 0.0 2.3 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EDN10068.1 - 0.064 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EDN10068.1 - 0.15 11.7 0.2 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding DDE_1 PF03184.14 EDN10071.1 - 6e-51 172.6 0.0 1.4e-50 171.4 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN10071.1 - 3.6e-06 26.8 0.0 7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_C2 PF00648.16 EDN10072.1 - 1.1e-52 178.8 6.4 6.5e-40 136.9 0.4 2.7 2 1 0 3 3 3 2 Calpain family cysteine protease Pkinase PF00069.20 EDN10073.1 - 9e-72 241.3 0.0 1.1e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN10073.1 - 1.8e-31 109.1 0.0 2.3e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN10073.1 - 0.0003 19.8 0.0 0.0005 19.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN10073.1 - 0.0057 16.4 0.1 0.015 15.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDN10073.1 - 0.0086 14.9 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 EDN10073.1 - 0.12 11.4 0.0 0.36 9.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EDN10073.1 - 0.16 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL 2OG-FeII_Oxy_2 PF13532.1 EDN10074.1 - 5.4e-22 78.5 0.0 9.6e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 EDN10074.1 - 1e-20 74.0 0.0 2.4e-20 72.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN10074.1 - 3.2e-08 32.9 0.7 0.002 17.2 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EDN10074.1 - 0.016 14.9 0.2 0.044 13.5 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EDN10074.1 - 0.079 11.9 0.3 7.2 5.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Amidase PF01425.16 EDN10075.1 - 6.4e-59 199.9 0.1 3.9e-43 147.9 0.2 2.0 1 1 1 2 2 2 2 Amidase HNH_2 PF13391.1 EDN10076.1 - 5.2e-10 38.9 0.0 1.1e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DUF4200 PF13863.1 EDN10077.1 - 0.076 12.9 2.5 0.093 12.6 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FAA_hydrolase_N PF09298.6 EDN10078.1 - 0.027 14.4 0.0 0.03 14.3 0.0 1.1 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal tRNA-synt_1b PF00579.20 EDN10079.1 - 2.5e-20 72.7 0.0 7e-20 71.3 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) RRM_1 PF00076.17 EDN10080.1 - 1e-16 60.3 0.0 1.9e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN10080.1 - 4e-10 39.5 0.0 7.8e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN10080.1 - 0.00053 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 6PGD PF00393.14 EDN10081.1 - 3e-133 443.5 0.0 4e-133 443.1 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EDN10081.1 - 6e-51 172.5 0.0 1e-50 171.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ub-Mut7C PF14451.1 EDN10081.1 - 0.052 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Mut7-C ubiquitin DNA_pol3_beta PF00712.14 EDN10081.1 - 0.2 11.5 0.0 0.66 9.8 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III beta subunit, N-terminal domain AD PF09793.4 EDN10082.1 - 1.4e-26 92.1 0.0 2.8e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain Macoilin PF09726.4 EDN10082.1 - 0.96 7.6 8.2 1.1 7.4 5.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Glyco_hydro_18 PF00704.23 EDN10083.1 - 3e-93 312.9 3.0 3.6e-93 312.7 2.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TPT PF03151.11 EDN10085.1 - 2.3e-31 108.5 9.6 2.3e-31 108.5 6.6 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EDN10085.1 - 8e-08 32.3 23.7 0.0001 22.3 1.6 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EDN10085.1 - 7.1e-06 25.1 13.9 1.1e-05 24.5 9.6 1.2 1 0 0 1 1 1 1 UAA transporter family DUF4346 PF14251.1 EDN10086.1 - 0.049 13.3 0.0 0.56 9.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4346) DNA_pol_phi PF04931.8 EDN10087.1 - 8.3e-53 179.3 9.1 1.2e-52 178.7 6.3 1.2 1 0 0 1 1 1 1 DNA polymerase phi AP_endonuc_2 PF01261.19 EDN10088.1 - 3.7e-22 78.6 0.0 5.3e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DLH PF01738.13 EDN10089.1 - 3e-17 62.6 0.0 3.8e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EDN10089.1 - 1.3e-07 31.4 0.0 1.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN10089.1 - 0.00026 20.9 0.1 0.12 12.2 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDN10089.1 - 0.039 13.1 0.2 0.2 10.8 0.0 2.0 1 1 1 2 2 2 0 Prolyl oligopeptidase family Mad3_BUB1_I PF08311.7 EDN10090.1 - 1.7e-44 150.6 0.0 2.2e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 ProSAAS PF07259.7 EDN10090.1 - 0.0064 16.0 1.6 0.011 15.3 1.1 1.3 1 0 0 1 1 1 1 ProSAAS precursor Pkinase PF00069.20 EDN10091.1 - 1.3e-09 37.6 0.0 1.6e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN10091.1 - 0.052 12.6 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Peptidase_C15 PF01470.12 EDN10093.1 - 7.7e-07 29.1 0.1 0.0073 16.1 0.0 3.4 2 1 0 3 3 3 2 Pyroglutamyl peptidase Pex14_N PF04695.8 EDN10093.1 - 1.7 8.6 12.6 0.73 9.8 6.5 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2360 PF10152.4 EDN10093.1 - 3.6 7.8 6.9 3.3 7.9 3.5 1.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) F-box-like PF12937.2 EDN10094.1 - 0.00051 19.7 0.2 0.0013 18.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN10094.1 - 0.016 14.8 0.0 0.056 13.1 0.0 1.8 1 0 0 1 1 1 0 F-box domain DUF4414 PF14377.1 EDN10094.1 - 0.086 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) PRANC PF09372.5 EDN10094.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 PRANC domain Rhodanese PF00581.15 EDN10095.1 - 6.6e-14 52.2 0.0 1.5e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Sld5 PF05916.6 EDN10096.1 - 3.4e-12 46.6 0.7 1.3e-11 44.7 0.4 1.9 1 1 1 2 2 2 1 GINS complex protein Cullin PF00888.17 EDN10097.1 - 9.7e-131 437.1 6.5 1.4e-130 436.6 4.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EDN10097.1 - 1.4e-29 101.6 1.9 4.2e-29 100.1 0.2 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain Rrf2 PF02082.15 EDN10097.1 - 0.024 14.7 0.2 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator TrmB PF01978.14 EDN10097.1 - 0.025 14.3 0.1 11 5.7 0.0 2.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.5 EDN10097.1 - 0.036 13.6 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_20 PF12840.2 EDN10097.1 - 0.13 12.0 0.5 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain zf-DNL PF05180.7 EDN10098.1 - 8e-06 25.4 0.1 1.5e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 DNL zinc finger DRIM PF07539.7 EDN10099.1 - 1.9e-50 169.9 0.1 8.6e-49 164.5 0.0 3.6 4 0 0 4 4 4 1 Down-regulated in metastasis HEAT PF02985.17 EDN10099.1 - 0.00036 20.3 1.3 12 6.2 0.0 6.8 6 0 0 6 6 6 2 HEAT repeat MIF PF01187.13 EDN10100.1 - 1.2e-16 60.7 0.0 1.3e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 EDN10100.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Tautomerase enzyme CpeT PF06206.6 EDN10100.1 - 0.14 11.8 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) CwfJ_C_1 PF04677.10 EDN10101.1 - 1.2e-25 89.5 0.0 2.6e-25 88.4 0.0 1.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EDN10101.1 - 3.2e-23 82.0 1.2 6.6e-23 81.0 0.9 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Metallophos PF00149.23 EDN10101.1 - 0.0019 17.6 0.0 0.0057 16.0 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF829 PF05705.9 EDN10102.1 - 1.1e-38 133.2 0.0 1.3e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EDN10102.1 - 0.0053 16.6 0.1 0.0077 16.1 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Corona_S2 PF01601.11 EDN10103.1 - 0.0083 14.2 12.9 0.011 13.8 8.9 1.1 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein LSR PF05624.9 EDN10103.1 - 0.29 10.9 30.4 0.49 10.1 21.1 1.4 1 0 0 1 1 1 0 Lipolysis stimulated receptor (LSR) Lamp PF01299.12 EDN10103.1 - 0.42 9.7 2.9 0.37 9.8 0.1 2.1 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) RCR PF12273.3 EDN10104.1 - 8.9e-27 94.2 14.4 1.1e-26 93.9 10.0 1.0 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SLAC1 PF03595.12 EDN10104.1 - 0.015 13.9 1.0 0.018 13.6 0.7 1.0 1 0 0 1 1 1 0 Voltage-dependent anion channel DUF4131 PF13567.1 EDN10104.1 - 0.052 12.9 1.2 0.059 12.7 0.8 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Tetraspannin PF00335.15 EDN10104.1 - 0.054 12.7 0.1 0.079 12.2 0.1 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF1183 PF06682.7 EDN10104.1 - 0.12 11.9 0.1 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Arf PF00025.16 EDN10105.1 - 3.8e-43 146.7 0.0 4.5e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EDN10105.1 - 4.1e-19 68.5 0.0 4.7e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN10105.1 - 9.1e-11 42.3 0.0 1.3e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EDN10105.1 - 1.9e-07 30.5 0.0 2.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EDN10105.1 - 3.6e-07 29.5 0.0 4.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EDN10105.1 - 4e-07 29.9 0.0 6.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDN10105.1 - 3.1e-05 23.4 0.0 0.00026 20.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EDN10105.1 - 0.00018 20.2 0.0 0.00052 18.8 0.0 1.6 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.18 EDN10105.1 - 0.00083 19.2 0.0 0.011 15.5 0.1 2.0 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 EDN10105.1 - 0.026 13.8 0.1 0.14 11.4 0.0 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B RNA_pol_Rpb2_6 PF00562.23 EDN10106.1 - 9.3e-116 386.7 0.0 1.3e-115 386.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EDN10106.1 - 4.9e-34 117.0 0.0 7.3e-34 116.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpa2_4 PF06883.7 EDN10106.1 - 7.9e-27 92.9 0.1 5e-26 90.4 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 EDN10106.1 - 4.4e-26 91.4 0.0 7.9e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EDN10106.1 - 4.2e-14 52.5 0.0 1.2e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EDN10106.1 - 0.00072 19.4 0.0 0.0019 18.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EDN10106.1 - 0.011 15.5 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 3 Proteasome PF00227.21 EDN10107.1 - 2.5e-48 163.8 0.3 3.1e-48 163.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 EDN10107.1 - 0.092 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF554) Pil1 PF13805.1 EDN10108.1 - 4.1e-95 317.9 2.8 5.3e-95 317.6 2.0 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2508 PF10704.4 EDN10108.1 - 0.51 10.5 3.8 1.8 8.7 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) SWI-SNF_Ssr4 PF08549.5 EDN10109.1 - 6.7e-144 480.7 32.4 4.3e-111 372.3 6.3 2.2 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1750) Ppx-GppA PF02541.11 EDN10110.1 - 4.1e-46 157.4 0.0 6e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Thi4 PF01946.12 EDN10112.1 - 1.2e-100 335.3 0.0 1.5e-100 335.0 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EDN10112.1 - 1.4e-07 30.7 0.0 2.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDN10112.1 - 2.1e-05 23.6 0.2 8.4e-05 21.6 0.2 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EDN10112.1 - 0.00011 22.1 0.8 0.00025 20.9 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EDN10112.1 - 0.00061 19.5 0.3 0.0023 17.7 0.0 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EDN10112.1 - 0.0051 16.8 0.0 0.0086 16.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDN10112.1 - 0.0053 16.6 0.4 0.013 15.4 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDN10112.1 - 0.02 13.7 0.5 0.071 11.9 0.3 1.8 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 EDN10112.1 - 0.06 12.4 0.1 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EDN10112.1 - 0.095 11.3 0.2 0.14 10.7 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 EDN10112.1 - 0.2 10.0 0.5 0.31 9.4 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Exo_endo_phos PF03372.18 EDN10113.1 - 4.3e-18 66.1 0.0 5.9e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 EDN10114.1 - 6.9e-28 95.4 5.8 5.8e-08 32.3 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EDN10114.1 - 0.00036 20.3 0.0 0.00056 19.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EDN10114.1 - 0.0017 16.6 0.1 0.089 10.9 0.1 2.3 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DUF3312 PF11768.3 EDN10114.1 - 0.023 12.9 0.0 0.032 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF1513 PF07433.6 EDN10114.1 - 0.078 11.8 0.0 0.3 9.9 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) Glyco_hydro_cc PF11790.3 EDN10115.1 - 7.4e-62 208.8 0.0 8.9e-62 208.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RED_N PF07808.8 EDN10116.1 - 3.9e-09 36.0 1.7 1.1e-08 34.6 1.2 1.8 1 0 0 1 1 1 1 RED-like protein N-terminal region zf-UBR PF02207.15 EDN10117.1 - 9.5e-18 63.6 15.8 3e-17 62.0 10.9 1.9 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EDN10117.1 - 3.7e-05 23.3 0.1 8.8e-05 22.1 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 EDN10117.1 - 0.0001 22.0 2.1 0.0001 22.0 1.4 4.4 4 0 0 4 4 4 1 Ring finger domain UCR_UQCRX_QCR9 PF05365.7 EDN10118.1 - 1.8e-28 97.9 0.9 2e-28 97.7 0.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.5 EDN10119.1 - 5.9e-13 48.1 1.5 1.2e-12 47.1 1.0 1.5 1 0 0 1 1 1 1 Mago binding AAA_13 PF13166.1 EDN10119.1 - 0.0073 14.8 3.9 0.0093 14.4 2.7 1.1 1 0 0 1 1 1 1 AAA domain Amino_oxidase PF01593.19 EDN10120.1 - 9.9e-23 80.9 0.1 2.1e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EDN10120.1 - 1.3e-12 47.5 0.1 3.9e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDN10120.1 - 1.1e-06 27.7 0.0 2.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDN10120.1 - 7.3e-05 23.1 0.1 0.029 14.7 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN10120.1 - 0.00013 21.8 0.0 0.002 17.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EDN10120.1 - 0.00037 19.0 0.1 0.0035 15.8 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EDN10120.1 - 0.0049 15.7 0.0 0.014 14.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EDN10120.1 - 0.0055 16.7 0.1 0.086 12.8 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDN10120.1 - 0.0061 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN10120.1 - 0.0072 15.4 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.11 EDN10120.1 - 0.017 14.5 0.4 0.43 10.0 0.0 2.7 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.2 EDN10120.1 - 0.043 12.8 0.1 0.068 12.2 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FMO-like PF00743.14 EDN10120.1 - 0.045 11.9 0.0 0.065 11.4 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like TrkA_N PF02254.13 EDN10120.1 - 0.18 11.8 0.8 0.95 9.4 0.0 2.5 3 0 0 3 3 3 0 TrkA-N domain zf-CCCH_2 PF14608.1 EDN10121.1 - 6.2e-09 35.5 52.1 4.8e-06 26.3 7.5 5.8 5 1 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 EDN10121.1 - 0.0044 17.0 0.1 0.0097 15.9 0.1 1.6 1 1 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Glyco_hydro_20 PF00728.17 EDN10122.1 - 9.6e-68 228.9 0.0 1.1e-67 228.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain p450 PF00067.17 EDN10124.1 - 1.1e-24 86.7 0.5 2.2e-14 52.8 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Annexin PF00191.15 EDN10125.1 - 8.1e-33 112.1 2.6 8.2e-11 41.6 0.0 4.5 4 1 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.1 EDN10125.1 - 0.0072 16.5 0.5 1.5 9.1 0.0 3.3 4 1 1 5 5 5 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Glyco_hydro_16 PF00722.16 EDN10126.1 - 4.6e-40 136.8 1.1 6.9e-40 136.3 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 tRNA-synt_1b PF00579.20 EDN10128.1 - 9.1e-62 208.8 0.0 1.1e-61 208.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Fer4_5 PF12801.2 EDN10128.1 - 0.16 11.7 0.5 0.29 10.9 0.4 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain RNA_pol_A_bac PF01000.21 EDN10129.1 - 6.9e-32 109.9 0.0 1.2e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EDN10129.1 - 1.8e-12 46.1 0.0 3.7e-12 45.1 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Herpes_UL47 PF03362.8 EDN10130.1 - 0.0035 15.7 0.0 0.0046 15.3 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus UL47 protein FTA2 PF13095.1 EDN10130.1 - 0.029 13.9 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 NUDIX PF00293.23 EDN10131.1 - 3e-18 65.7 0.2 3.4e-18 65.5 0.2 1.0 1 0 0 1 1 1 1 NUDIX domain TraI_2 PF07514.6 EDN10131.1 - 0.014 14.1 1.1 0.028 13.1 0.8 1.5 1 1 0 1 1 1 0 Putative helicase ATE_C PF04377.10 EDN10132.1 - 4.3e-29 101.1 1.5 1e-28 99.9 1.1 1.8 1 1 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EDN10132.1 - 2.4e-18 65.6 1.0 4.7e-18 64.7 0.7 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus PBP_like PF12727.2 EDN10133.1 - 0.11 11.4 0.0 0.22 10.4 0.0 1.5 2 0 0 2 2 2 0 PBP superfamily domain ACC_epsilon PF13822.1 EDN10134.1 - 0.021 15.1 0.1 0.038 14.3 0.0 1.5 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Conotoxin PF02950.12 EDN10134.1 - 1.3 9.8 9.3 7.8 7.3 6.5 1.9 1 1 0 1 1 1 0 Conotoxin Cytochrom_C PF00034.16 EDN10135.1 - 5.6e-11 43.1 0.0 8.4e-11 42.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EDN10135.1 - 4e-08 33.3 1.0 1.6e-07 31.3 0.7 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EDN10135.1 - 0.00093 18.6 0.8 0.0038 16.6 0.5 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain CCP_MauG PF03150.9 EDN10135.1 - 0.09 13.0 0.1 0.16 12.2 0.0 1.4 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase Orbi_NS3 PF01616.11 EDN10136.1 - 0.05 12.5 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Orbivirus NS3 RNase_PH PF01138.16 EDN10137.1 - 3.9e-08 33.6 0.3 7.8e-07 29.4 0.2 2.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EDN10137.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Pkinase PF00069.20 EDN10139.1 - 8.8e-61 205.3 0.0 1.2e-60 204.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN10139.1 - 2.1e-36 125.3 0.0 3.1e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EDN10139.1 - 0.021 13.6 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1387 PF07139.6 EDN10139.1 - 0.21 11.1 2.8 0.51 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) RICH PF05062.7 EDN10140.1 - 0.04 14.0 4.5 0.22 11.6 0.7 2.0 2 0 0 2 2 2 0 RICH domain DUF3656 PF12392.3 EDN10140.1 - 0.068 13.2 0.1 0.07 13.2 0.0 1.0 1 0 0 1 1 1 0 Collagenase Stc1 PF12898.2 EDN10141.1 - 8.7e-24 83.4 5.1 1.4e-23 82.7 3.5 1.3 1 0 0 1 1 1 1 Stc1 domain DUF1724 PF08350.5 EDN10141.1 - 0.02 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) Stn1 PF10451.4 EDN10142.1 - 1.7e-14 53.3 1.4 9.4e-08 31.1 0.1 2.2 2 0 0 2 2 2 2 Telomere regulation protein Stn1 DUF2677 PF10838.3 EDN10143.1 - 0.084 12.5 0.4 0.12 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2677) dCMP_cyt_deam_1 PF00383.17 EDN10144.1 - 1.8e-09 37.1 0.0 3.2e-08 33.1 0.0 2.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DnaJ PF00226.26 EDN10145.1 - 1.2e-24 85.7 2.0 2.7e-24 84.6 1.4 1.6 1 0 0 1 1 1 1 DnaJ domain Usp PF00582.21 EDN10146.1 - 1.1e-19 70.9 3.8 6.8e-13 49.0 0.1 2.8 3 0 0 3 3 3 2 Universal stress protein family CDC45 PF02724.9 EDN10146.1 - 1.6 6.6 6.8 2.4 6.1 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PGA2 PF07543.7 EDN10146.1 - 5.3 6.8 10.1 10 5.8 6.4 1.9 1 1 0 1 1 1 0 Protein trafficking PGA2 Peptidase_S10 PF00450.17 EDN10147.1 - 2.1e-77 261.0 0.0 4.5e-77 259.9 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase ATP-synt_ab PF00006.20 EDN10148.1 - 1.1e-61 208.1 0.0 1.4e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDN10148.1 - 1.5e-16 60.8 0.0 2.8e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDN10148.1 - 7.4e-10 38.9 0.3 1.5e-09 37.9 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EDN10148.1 - 0.072 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 HAS barrel domain GFO_IDH_MocA PF01408.17 EDN10149.1 - 6.1e-13 49.3 0.2 1.4e-12 48.1 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EDN10149.1 - 9.7e-10 38.2 0.0 1.7e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PALP PF00291.20 EDN10150.1 - 5.5e-44 150.6 1.1 8.3e-44 150.0 0.8 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Trp_syntA PF00290.15 EDN10150.1 - 1.4e-34 118.8 0.0 2.4e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain Peptidase_A21 PF03566.8 EDN10154.1 - 0.94 7.4 3.7 0.96 7.4 2.6 1.0 1 0 0 1 1 1 0 Peptidase family A21 ADH_zinc_N PF00107.21 EDN10156.1 - 7.5e-24 83.7 0.1 1.2e-23 83.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDN10156.1 - 3.6e-09 37.6 0.0 9.9e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN10156.1 - 0.0001 21.9 0.0 0.00025 20.7 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EDN10156.1 - 0.0041 17.0 0.4 0.27 11.1 0.2 2.3 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EDN10156.1 - 0.0055 16.7 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding MAPEG PF01124.13 EDN10157.1 - 1.3e-18 66.8 0.8 1.5e-18 66.6 0.5 1.0 1 0 0 1 1 1 1 MAPEG family GYF PF02213.11 EDN10158.1 - 8.9e-16 57.2 0.1 2.5e-15 55.7 0.1 1.9 1 0 0 1 1 1 1 GYF domain Aminotran_5 PF00266.14 EDN10159.1 - 2.4e-25 89.0 0.0 3.3e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EDN10159.1 - 4e-06 26.0 0.0 5.2e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EDN10159.1 - 0.0096 14.2 0.0 0.014 13.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DSBA PF01323.15 EDN10160.1 - 1.9e-14 53.6 0.0 2.2e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 EDN10160.1 - 0.011 15.5 0.1 0.019 14.7 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.1 EDN10160.1 - 0.018 15.0 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Spc24 PF08286.6 EDN10162.1 - 2.1e-38 130.6 0.7 9.6e-38 128.5 0.0 1.9 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Viral_P18 PF04521.8 EDN10162.1 - 0.27 10.6 5.6 1.5 8.3 0.5 2.2 1 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein APG6 PF04111.7 EDN10162.1 - 0.32 9.9 3.1 0.42 9.6 2.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Syntaxin PF00804.20 EDN10162.1 - 1 9.5 5.0 1.2 9.3 1.6 2.1 1 1 1 2 2 2 0 Syntaxin Fis1_TPR_C PF14853.1 EDN10163.1 - 5.6e-25 86.9 1.0 9.7e-25 86.2 0.7 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EDN10163.1 - 6.4e-16 57.3 0.1 1.2e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat zf-RING_2 PF13639.1 EDN10163.1 - 4.6e-13 48.7 8.6 7.9e-13 48.0 5.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDN10163.1 - 2.4e-08 33.9 3.1 4.7e-08 33.0 2.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EDN10163.1 - 2.8e-08 33.2 3.4 4.7e-08 32.5 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN10163.1 - 5.7e-07 29.4 7.2 9.9e-07 28.6 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDN10163.1 - 8.9e-06 25.2 5.8 1.5e-05 24.5 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN10163.1 - 1.4e-05 24.6 4.3 2.4e-05 23.9 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EDN10163.1 - 0.00087 19.0 2.7 0.0017 18.1 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_2 PF07719.12 EDN10163.1 - 0.022 14.6 1.3 0.044 13.7 0.9 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDN10163.1 - 0.032 14.9 1.0 0.069 13.8 0.2 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat zf-HC5HC2H PF13771.1 EDN10163.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.24 EDN10163.1 - 0.061 13.0 5.1 0.099 12.3 3.5 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.1 EDN10163.1 - 0.064 13.2 0.1 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain Vps39_2 PF10367.4 EDN10163.1 - 0.11 12.7 0.0 4.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_4 PF14570.1 EDN10163.1 - 0.25 10.9 3.1 0.43 10.1 2.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EDN10163.1 - 0.91 9.5 5.1 3.9 7.4 3.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EDN10163.1 - 1.6 8.8 7.1 3.1 7.9 4.9 1.5 1 0 0 1 1 1 0 RING-variant domain DUF3431 PF11913.3 EDN10164.1 - 3.2e-87 291.6 0.4 5.6e-87 290.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3431) DUF2034 PF10356.4 EDN10166.1 - 9.3e-35 119.4 0.0 5.8e-19 67.9 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EDN10166.1 - 3.4e-08 33.2 0.0 7e-08 32.2 0.0 1.5 2 0 0 2 2 2 1 Restriction endonuclease Med21 PF11221.3 EDN10167.1 - 2.9e-54 182.9 14.7 1.8e-53 180.3 10.2 1.8 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Spore_III_AB PF09548.5 EDN10167.1 - 0.0058 16.3 0.2 0.011 15.5 0.0 1.4 2 0 0 2 2 2 1 Stage III sporulation protein AB (spore_III_AB) ATG16 PF08614.6 EDN10167.1 - 0.019 14.8 0.5 0.028 14.2 0.3 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SPX PF03105.14 EDN10167.1 - 0.045 13.5 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 SPX domain DUF2126 PF09899.4 EDN10167.1 - 0.16 9.9 1.2 0.16 9.9 0.3 1.4 1 1 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PRCC PF10253.4 EDN10167.1 - 0.23 12.1 3.0 0.32 11.6 2.1 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting TFIIA PF03153.8 EDN10167.1 - 0.27 11.0 2.1 0.3 10.9 1.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med9 PF07544.8 EDN10167.1 - 0.31 10.7 6.9 0.29 10.8 2.7 2.4 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 EDN10167.1 - 0.37 10.3 4.8 0.16 11.5 1.7 1.6 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 EDN10167.1 - 0.38 9.7 2.1 0.57 9.1 1.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ATP-synt_E PF05680.7 EDN10167.1 - 1.2 9.1 4.4 0.42 10.6 1.0 1.8 2 0 0 2 2 2 0 ATP synthase E chain SNF2_N PF00176.18 EDN10168.1 - 4.2e-60 203.0 0.2 6.3e-60 202.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN10168.1 - 2.6e-08 33.6 0.1 2.1e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN10168.1 - 8.8e-06 25.3 0.0 2.5e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EDN10168.1 - 0.0077 15.9 2.6 0.015 15.0 1.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain HIRAN PF08797.6 EDN10168.1 - 0.099 12.5 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 HIRAN domain PI3_PI4_kinase PF00454.22 EDN10169.1 - 1.2e-38 132.9 0.0 2e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GATA PF00320.22 EDN10170.1 - 4.1e-16 58.0 3.0 1.1e-15 56.7 2.1 1.8 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EDN10170.1 - 0.0085 15.3 0.5 0.019 14.2 0.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Serinc PF03348.10 EDN10173.1 - 9.3e-175 581.4 8.8 1.1e-174 581.1 6.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DNA_mis_repair PF01119.14 EDN10174.1 - 3.1e-19 68.5 0.0 7e-17 60.9 0.0 3.3 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EDN10174.1 - 3.3e-18 65.6 0.5 5e-17 61.8 0.3 2.8 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EDN10174.1 - 4.3e-13 49.1 0.5 1.3e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDN10174.1 - 5e-12 45.5 0.0 1.3e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GCN5L1 PF06320.8 EDN10175.1 - 6e-11 42.2 5.9 7.6e-11 41.9 4.1 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF848 PF05852.6 EDN10175.1 - 0.013 15.3 7.3 0.015 15.1 4.5 1.5 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF3552 PF12072.3 EDN10175.1 - 0.035 13.3 10.6 0.067 12.3 7.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF3735 PF12537.3 EDN10175.1 - 0.075 13.0 1.2 0.13 12.3 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3735) AAA_13 PF13166.1 EDN10175.1 - 0.14 10.6 6.2 0.16 10.4 4.3 1.0 1 0 0 1 1 1 0 AAA domain DUF2884 PF11101.3 EDN10175.1 - 0.15 11.3 3.7 0.097 12.0 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) HAUS6_N PF14661.1 EDN10175.1 - 0.33 10.2 8.9 1.7 7.9 6.3 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF342 PF03961.8 EDN10175.1 - 0.42 8.9 6.1 0.48 8.7 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HAUS-augmin3 PF14932.1 EDN10175.1 - 0.69 9.0 9.7 0.75 8.9 6.0 1.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DASH_Dad2 PF08654.5 EDN10175.1 - 0.84 9.6 6.0 0.58 10.1 2.1 2.0 1 1 2 3 3 3 0 DASH complex subunit Dad2 zf-C4H2 PF10146.4 EDN10175.1 - 1.7 8.6 7.2 2.6 8.0 5.0 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF2098 PF09871.4 EDN10175.1 - 4.5 7.2 9.6 0.96 9.4 0.4 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) CPSase_L_D2 PF02786.12 EDN10176.1 - 1.4e-51 174.7 0.0 2.1e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EDN10176.1 - 9.6e-30 102.9 0.0 1.7e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EDN10176.1 - 2.9e-29 101.1 0.0 1.8e-28 98.6 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EDN10176.1 - 1.3e-15 57.5 0.0 2.4e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EDN10176.1 - 9e-13 47.6 0.0 4.4e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EDN10176.1 - 5.4e-12 45.1 2.6 1.3e-11 43.9 0.3 2.7 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 EDN10176.1 - 2.6e-10 40.0 0.0 5.2e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EDN10176.1 - 2e-07 30.5 0.0 3.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EDN10176.1 - 8.6e-05 22.4 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EDN10176.1 - 0.0007 19.2 0.0 0.002 17.7 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD_2 PF12700.2 EDN10176.1 - 0.0048 16.1 0.0 0.0077 15.4 0.0 1.3 1 0 0 1 1 1 1 HlyD family secretion protein RnfC_N PF13375.1 EDN10176.1 - 0.0051 16.5 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.1 EDN10176.1 - 0.015 15.6 0.5 5.6 7.3 0.0 2.9 3 0 0 3 3 3 0 HlyD family secretion protein RimK PF08443.6 EDN10176.1 - 0.019 14.4 0.0 0.052 13.0 0.0 1.7 2 0 0 2 2 2 0 RimK-like ATP-grasp domain DUF2118 PF09891.4 EDN10176.1 - 0.067 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Carboxyl_trans PF01039.17 EDN10177.1 - 2.9e-53 180.9 0.0 3.6e-45 154.2 0.0 2.1 1 1 1 2 2 2 2 Carboxyl transferase domain BCDHK_Adom3 PF10436.4 EDN10178.1 - 4.7e-43 146.5 0.1 6.2e-43 146.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EDN10178.1 - 1.4e-14 53.7 0.0 7.6e-14 51.3 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FleQ PF06490.6 EDN10178.1 - 0.16 12.1 0.1 8.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ HATPase_c_2 PF13581.1 EDN10178.1 - 0.18 11.5 0.3 0.77 9.5 0.0 2.2 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain DUF3425 PF11905.3 EDN10179.1 - 5.2e-26 91.1 2.3 8.3e-26 90.4 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF663 PF04950.7 EDN10181.1 - 4.9e-79 265.3 0.0 4.9e-79 265.3 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EDN10181.1 - 1.8e-26 91.5 0.0 4e-26 90.3 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EDN10181.1 - 5.2e-07 29.2 1.3 7.5e-05 22.2 0.0 2.5 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EDN10181.1 - 1.9e-05 24.8 0.0 4.7e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN10181.1 - 0.00012 22.1 0.0 0.00032 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EDN10181.1 - 0.00015 22.0 0.0 0.00041 20.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDN10181.1 - 0.0003 21.5 1.5 0.00096 19.9 0.0 2.8 3 0 0 3 3 1 1 AAA domain MobB PF03205.9 EDN10181.1 - 0.00064 19.4 0.2 0.0015 18.2 0.2 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EDN10181.1 - 0.0012 18.3 0.0 0.0035 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EDN10181.1 - 0.0013 18.6 0.1 0.0042 17.0 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EDN10181.1 - 0.0014 18.4 1.7 0.0018 18.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain Miro PF08477.8 EDN10181.1 - 0.0018 18.7 0.4 0.0048 17.3 0.0 1.9 2 0 0 2 2 1 1 Miro-like protein PduV-EutP PF10662.4 EDN10181.1 - 0.0033 16.9 0.0 0.026 14.0 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EDN10181.1 - 0.0035 17.0 0.0 0.0069 16.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EDN10181.1 - 0.0048 15.7 0.0 0.0091 14.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_24 PF13479.1 EDN10181.1 - 0.0062 16.1 0.3 0.015 14.8 0.2 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EDN10181.1 - 0.0066 16.1 0.3 0.016 14.9 0.2 1.6 1 0 0 1 1 1 1 NTPase AAA_14 PF13173.1 EDN10181.1 - 0.0086 15.9 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EDN10181.1 - 0.0092 16.2 1.2 0.018 15.3 0.0 2.0 2 0 0 2 2 1 1 ABC transporter AAA_18 PF13238.1 EDN10181.1 - 0.0095 16.2 2.3 0.015 15.6 0.0 2.5 2 0 0 2 2 1 1 AAA domain cobW PF02492.14 EDN10181.1 - 0.0099 15.3 0.5 0.019 14.4 0.1 1.6 2 0 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 EDN10181.1 - 0.01 14.9 0.0 0.01 14.9 0.0 2.0 2 0 0 2 2 1 0 Zeta toxin AAA_19 PF13245.1 EDN10181.1 - 0.011 15.5 0.1 0.031 14.0 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EDN10181.1 - 0.016 15.3 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EDN10181.1 - 0.019 14.1 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 EDN10181.1 - 0.027 13.4 0.0 0.051 12.5 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain Arch_ATPase PF01637.13 EDN10181.1 - 0.045 13.4 1.6 0.049 13.3 0.0 1.8 2 0 0 2 2 1 0 Archaeal ATPase AAA_5 PF07728.9 EDN10181.1 - 0.048 13.3 0.2 0.14 11.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EDN10181.1 - 0.093 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 EDN10181.1 - 0.11 11.9 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.1 EDN10181.1 - 0.28 10.7 5.2 0.67 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain adh_short PF00106.20 EDN10183.1 - 6.8e-20 71.6 0.1 1.1e-19 71.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN10183.1 - 5e-10 39.5 0.1 0.00023 21.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN10183.1 - 0.0013 18.4 0.0 0.0029 17.2 0.0 1.6 1 1 0 1 1 1 1 KR domain RRM_6 PF14259.1 EDN10184.1 - 1.1e-10 41.3 0.0 1.4e-09 37.8 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN10184.1 - 2.3e-10 40.1 0.0 4.5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EDN10184.1 - 4.7e-08 33.0 0.1 1e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.1 EDN10184.1 - 8e-05 22.3 0.0 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.17 EDN10184.1 - 0.00012 21.6 0.1 0.0028 17.2 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PrpF PF04303.8 EDN10184.1 - 0.11 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 PrpF protein DUF4407 PF14362.1 EDN10184.1 - 3.5 6.4 8.8 5.5 5.8 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF737 PF05300.6 EDN10184.1 - 4.6 7.1 17.0 24 4.8 11.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF737) GTP_EFTU PF00009.22 EDN10185.1 - 3e-61 206.1 0.0 4.1e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EDN10185.1 - 2e-38 130.6 0.0 5.8e-38 129.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EDN10185.1 - 1.2e-20 73.1 0.0 3.6e-20 71.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 EDN10185.1 - 1.5e-05 24.8 0.0 3.8e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Solute_trans_a PF03619.11 EDN10188.1 - 8.2e-43 146.6 5.5 9e-25 87.5 0.1 3.1 1 1 2 3 3 3 3 Organic solute transporter Ostalpha PGG PF13962.1 EDN10189.1 - 0.093 12.3 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function Dynactin PF12455.3 EDN10191.1 - 6.5e-96 320.4 2.0 6.5e-96 320.4 1.4 3.2 4 1 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 EDN10191.1 - 7.4e-06 25.5 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain HALZ PF02183.13 EDN10191.1 - 0.0016 18.1 1.2 0.0016 18.1 0.8 9.0 7 2 5 12 12 12 2 Homeobox associated leucine zipper Phycobilisome PF00502.14 EDN10191.1 - 0.005 16.6 0.5 0.018 14.7 0.4 2.0 1 0 0 1 1 1 1 Phycobilisome protein DUF2353 PF09789.4 EDN10191.1 - 3.1 6.9 59.8 0.051 12.8 2.9 3.7 2 1 1 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) Cut8_N PF14482.1 EDN10191.1 - 4.5 7.3 7.6 0.31 11.0 0.8 2.3 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Hemerythrin PF01814.18 EDN10192.1 - 2.9e-08 33.9 0.1 3.7e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HAD_2 PF13419.1 EDN10193.1 - 7.6e-28 97.9 0.1 1.3e-27 97.1 0.1 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN10193.1 - 0.0045 16.6 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDN10193.1 - 0.0095 16.3 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NT5C PF06941.7 EDN10193.1 - 0.092 12.2 0.0 0.62 9.5 0.0 2.2 3 0 0 3 3 3 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) KH_1 PF00013.24 EDN10196.1 - 2.2e-27 94.4 3.3 1e-07 31.4 0.4 7.1 8 0 0 8 8 8 5 KH domain KH_3 PF13014.1 EDN10196.1 - 2.7e-23 81.1 3.4 0.0003 20.3 0.3 6.9 6 0 0 6 6 6 5 KH domain OTT_1508_deam PF14441.1 EDN10197.1 - 1.5e-19 70.2 0.3 2.9e-19 69.2 0.2 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Chitin_synth_2 PF03142.10 EDN10198.1 - 1e-256 852.4 0.7 1.6e-256 851.8 0.5 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EDN10198.1 - 9.2e-177 589.1 0.0 1.2e-176 588.7 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 EDN10198.1 - 2.5e-17 62.3 2.8 7.6e-17 60.8 1.5 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EDN10198.1 - 3.5e-15 56.2 3.0 6.8e-15 55.2 2.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDN10198.1 - 1.2e-14 54.7 0.1 3.5e-11 43.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EDN10198.1 - 2.3e-06 27.2 0.0 0.15 11.8 0.0 3.1 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 EDN10198.1 - 0.00037 20.2 0.0 0.022 14.4 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EDN10198.1 - 0.0019 17.5 0.2 0.045 13.0 0.1 2.8 2 1 0 2 2 2 1 Glycosyl transferase family 21 AAA_16 PF13191.1 EDN10198.1 - 0.03 14.3 0.2 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EDN10198.1 - 0.045 13.9 0.0 0.18 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain VirD1 PF07328.6 EDN10198.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 Chitin_synth_2 PF03142.10 EDN10199.1 - 3.6e-175 583.3 0.0 7.2e-175 582.3 0.0 1.4 2 0 0 2 2 2 1 Chitin synthase Myosin_head PF00063.16 EDN10199.1 - 4.3e-63 213.4 0.0 9.5e-63 212.3 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EDN10199.1 - 1.9e-20 72.4 0.0 3.6e-12 45.9 0.0 2.8 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EDN10199.1 - 1.9e-16 59.5 2.7 1.2e-15 56.9 1.6 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EDN10199.1 - 6.5e-16 58.6 0.2 6.5e-16 58.6 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDN10199.1 - 9.7e-15 54.9 0.0 2.1e-12 47.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EDN10199.1 - 4.4e-06 26.1 0.0 2.6e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EDN10199.1 - 0.0068 16.1 0.0 0.12 12.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Peptidase_S8 PF00082.17 EDN10200.1 - 1.9e-48 165.0 6.8 2.5e-48 164.6 4.7 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EDN10200.1 - 3.5e-10 40.3 0.1 7.3e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 PLDc_2 PF13091.1 EDN10201.1 - 1.5e-19 69.9 0.3 8.3e-11 41.7 0.1 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EDN10201.1 - 0.00027 20.6 0.2 0.36 10.6 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 EDN10201.1 - 0.04 12.8 0.0 0.16 10.8 0.0 1.9 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB TPP_enzyme_N PF02776.13 EDN10202.1 - 1.1e-36 125.9 0.5 2.9e-36 124.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDN10202.1 - 5.1e-21 74.8 0.5 1.6e-20 73.2 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EDN10202.1 - 3e-19 69.1 0.0 5.1e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4248 PF14053.1 EDN10202.1 - 0.0083 15.6 0.2 0.02 14.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4248) FCH PF00611.18 EDN10202.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain TatD_DNase PF01026.16 EDN10204.1 - 5.7e-28 97.8 0.0 9.8e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase Abhydrolase_6 PF12697.2 EDN10205.1 - 4.6e-28 98.6 2.3 4.5e-27 95.4 1.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN10205.1 - 1e-14 54.6 0.0 2e-11 43.8 0.0 3.0 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN10205.1 - 3.2e-13 49.6 0.0 7.2e-11 42.0 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 EDN10205.1 - 0.00016 21.1 0.0 0.00035 20.0 0.0 1.6 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 EDN10205.1 - 0.0005 19.2 0.0 0.00092 18.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.3 EDN10205.1 - 0.002 17.9 0.0 0.0057 16.4 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 EDN10205.1 - 0.0044 15.9 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.15 EDN10205.1 - 0.014 15.6 0.2 0.63 10.2 0.0 2.8 3 0 0 3 3 3 0 Thioesterase domain Abhydrolase_2 PF02230.11 EDN10205.1 - 0.038 13.4 0.0 12 5.2 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF2305 PF10230.4 EDN10205.1 - 0.046 13.1 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EDN10205.1 - 0.046 13.3 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 EDN10205.1 - 0.07 12.6 0.0 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ndr PF03096.9 EDN10205.1 - 0.26 9.7 0.0 0.41 9.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family Golgin_A5 PF09787.4 EDN10205.1 - 0.62 8.5 6.1 0.94 7.9 4.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spo7 PF03907.8 EDN10206.1 - 7.4e-47 159.6 0.0 1.2e-46 158.9 0.0 1.3 1 0 0 1 1 1 1 Spo7-like protein Suf PF05843.9 EDN10206.1 - 3.1 7.4 5.9 4.1 7.0 4.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med3 PF11593.3 EDN10206.1 - 5.9 6.0 10.4 7.9 5.6 7.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PAT1 PF09770.4 EDN10206.1 - 9.8 4.2 19.1 12 4.0 13.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MCM PF00493.18 EDN10207.1 - 2.9e-122 407.5 0.3 4e-122 407.1 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDN10207.1 - 1.5e-16 60.9 0.0 4.5e-16 59.4 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDN10207.1 - 9.3e-07 28.2 0.0 1.2e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EDN10207.1 - 0.0042 16.6 0.0 0.0099 15.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDN10207.1 - 0.1 12.1 0.0 0.32 10.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain PPR_3 PF13812.1 EDN10208.1 - 1.8e-22 77.6 3.9 0.00013 22.0 0.0 9.3 9 0 0 9 9 9 5 Pentatricopeptide repeat domain PPR_2 PF13041.1 EDN10208.1 - 3.9e-18 65.1 0.1 3.4e-08 33.3 0.0 6.0 5 1 1 6 6 6 3 PPR repeat family PPR PF01535.15 EDN10208.1 - 6.5e-12 44.5 3.6 0.042 13.8 0.0 9.0 10 0 0 10 10 10 3 PPR repeat PPR_1 PF12854.2 EDN10208.1 - 2.8e-06 26.7 0.0 4 7.0 0.0 5.3 5 0 0 5 5 5 3 PPR repeat TPR_16 PF13432.1 EDN10208.1 - 0.00045 20.7 5.8 2.6 8.8 0.0 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDN10208.1 - 0.0063 17.0 2.1 2 9.2 0.0 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat p450 PF00067.17 EDN10210.1 - 2.8e-55 187.7 0.0 4e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rhodanese PF00581.15 EDN10211.1 - 0.0023 18.2 0.0 0.0062 16.8 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain Ribosomal_60s PF00428.14 EDN10211.1 - 0.078 13.3 7.1 0.54 10.6 0.7 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein SLX9 PF15341.1 EDN10211.1 - 0.45 10.9 5.9 2.2 8.7 0.0 2.6 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 Chorion_2 PF03964.10 EDN10211.1 - 1.8 9.1 6.3 11 6.6 0.1 2.6 3 0 0 3 3 3 0 Chorion family 2 DUF2188 PF09954.4 EDN10211.1 - 2.6 8.0 7.2 1.3 8.9 1.6 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) GTP_EFTU PF00009.22 EDN10212.1 - 1.3e-31 109.4 0.0 1.3e-31 109.4 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EDN10212.1 - 5.8e-19 67.9 0.1 1.6e-18 66.5 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EDN10212.1 - 1.5e-11 44.2 0.8 3.2e-09 36.7 0.0 3.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDN10212.1 - 9e-06 25.6 1.8 1.9e-05 24.5 0.0 2.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase Miro PF08477.8 EDN10212.1 - 0.0066 16.9 0.0 0.0066 16.9 0.0 3.0 3 0 0 3 3 3 1 Miro-like protein ATP_bind_1 PF03029.12 EDN10212.1 - 0.014 14.9 0.0 0.034 13.7 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein GTP_EFTU_D4 PF14578.1 EDN10212.1 - 0.016 14.8 0.1 0.07 12.7 0.1 2.1 1 1 0 1 1 1 0 Elongation factor Tu domain 4 AAA_16 PF13191.1 EDN10212.1 - 0.13 12.2 0.0 0.13 12.2 0.0 3.5 1 1 1 2 2 2 0 AAA ATPase domain MMS1_N PF10433.4 EDN10213.1 - 1.5e-138 462.1 0.0 3.2e-138 461.0 0.0 1.5 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RabGAP-TBC PF00566.13 EDN10214.1 - 3.4e-23 82.2 0.1 5e-23 81.7 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain YqhR PF11085.3 EDN10215.1 - 0.0082 15.6 0.0 0.0094 15.5 0.0 1.1 1 0 0 1 1 1 1 Conserved membrane protein YqhR DUF751 PF05421.6 EDN10215.1 - 0.45 10.8 2.7 1.6 9.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF751) ubiquitin PF00240.18 EDN10216.1 - 1.3e-34 117.3 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EDN10216.1 - 7.5e-31 105.5 11.0 1.2e-30 104.8 7.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EDN10216.1 - 4.4e-20 71.1 0.7 6.5e-20 70.5 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDN10216.1 - 7.1e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDN10216.1 - 0.00011 21.9 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EDN10216.1 - 0.0074 16.1 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDN10216.1 - 0.011 15.9 0.1 0.012 15.8 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EDN10216.1 - 0.085 12.9 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Fer2_3 PF13085.1 EDN10216.1 - 0.25 11.1 1.8 1.2 9.0 1.2 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain eIF-5a PF01287.15 EDN10218.1 - 4e-25 87.5 1.6 5.6e-25 87.0 1.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EDN10218.1 - 0.0018 17.9 0.3 0.0018 17.9 0.2 1.8 2 0 0 2 2 2 1 KOW motif EFP_N PF08207.7 EDN10218.1 - 0.0094 15.7 0.2 0.041 13.7 0.0 2.1 3 0 0 3 3 3 1 Elongation factor P (EF-P) KOW-like domain Response_reg PF00072.19 EDN10218.1 - 0.11 12.4 0.5 0.16 11.9 0.4 1.5 1 1 0 1 1 1 0 Response regulator receiver domain Vps52 PF04129.7 EDN10219.1 - 2.5e-87 293.5 1.9 1.8e-58 198.3 1.3 3.1 1 1 2 3 3 3 3 Vps52 / Sac2 family Sec3_C PF09763.4 EDN10219.1 - 3.9e-08 31.9 3.1 5.9e-08 31.3 2.1 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 IFT57 PF10498.4 EDN10219.1 - 0.028 13.1 1.3 0.062 12.0 0.9 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 P_C PF06640.6 EDN10219.1 - 2.7 7.9 8.1 0.21 11.5 2.2 1.6 2 0 0 2 2 2 0 P protein C-terminus DAO PF01266.19 EDN10220.1 - 2.5e-53 181.2 1.8 2.9e-53 181.0 1.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDN10220.1 - 0.00039 20.3 0.0 0.0009 19.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EDN10220.1 - 0.056 13.5 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDN10220.1 - 0.082 12.7 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fe-ADH PF00465.14 EDN10221.1 - 4.7e-21 74.8 1.1 1.4e-17 63.3 0.0 2.0 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase RRM_1 PF00076.17 EDN10223.1 - 2.6e-78 257.6 8.9 1.4e-20 72.7 0.3 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN10223.1 - 2.5e-52 174.7 1.4 2.1e-13 50.0 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN10223.1 - 1.2e-34 117.9 0.8 3e-07 30.1 0.1 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CbiG_mid PF11761.3 EDN10223.1 - 3.6e-05 23.9 0.0 0.99 9.6 0.0 3.5 3 0 0 3 3 3 2 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.1 EDN10223.1 - 0.00025 20.7 0.1 16 5.3 0.0 4.6 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif PABP PF00658.13 EDN10223.1 - 0.00046 19.8 2.5 0.00068 19.2 0.0 2.6 4 0 0 4 4 4 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 EDN10223.1 - 0.0013 18.4 4.4 1.6 8.5 0.1 3.8 2 1 1 3 3 3 2 Limkain b1 HECT PF00632.20 EDN10224.1 - 4.9e-81 272.3 0.0 8.3e-81 271.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EDN10224.1 - 0.0046 16.4 1.5 0.016 14.7 1.0 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif MRP-L27 PF09809.4 EDN10225.1 - 3e-13 49.3 0.2 4.6e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 HAUS6_N PF14661.1 EDN10225.1 - 0.012 15.0 0.8 0.014 14.8 0.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Utp14 PF04615.8 EDN10226.1 - 9.1e-171 569.6 54.9 2.2e-130 436.1 32.3 3.1 1 1 2 3 3 3 2 Utp14 protein Glyco_hydro_81 PF03639.8 EDN10227.1 - 1.6e-201 670.9 0.0 2e-201 670.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Antimicrobial10 PF08105.6 EDN10228.1 - 0.059 12.9 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Metchnikowin family Dickkopf_N PF04706.7 EDN10228.1 - 1.5 9.0 7.7 2.1 8.5 5.3 1.2 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Toxin_22 PF08092.6 EDN10228.1 - 6.3 6.7 6.7 2.3 8.1 0.8 2.1 2 0 0 2 2 2 0 Magi peptide toxin family Na_Ca_ex PF01699.19 EDN10231.1 - 1.1e-45 154.7 37.6 1.3e-23 83.1 8.4 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Ribosomal_S7 PF00177.16 EDN10232.1 - 1.3e-24 86.4 0.0 4.2e-24 84.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e Dimer_Tnp_hAT PF05699.9 EDN10232.1 - 0.065 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Peptidase_S28 PF05577.7 EDN10233.1 - 2.6e-50 171.2 0.0 2.5e-49 168.0 0.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EDN10233.1 - 0.0026 17.6 0.0 0.08 12.8 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDN10233.1 - 0.0064 15.7 0.1 0.025 13.8 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Na_sulph_symp PF00939.14 EDN10234.1 - 6.1e-27 94.6 31.1 9.7e-27 93.9 21.6 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EDN10234.1 - 1.4e-15 56.7 43.0 5.4e-14 51.5 18.7 2.1 1 1 1 2 2 2 2 Citrate transporter DUF3270 PF11674.3 EDN10234.1 - 6.6 6.8 15.8 0.14 12.1 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) Ribosomal_S8e PF01201.17 EDN10235.1 - 2.3e-31 108.6 5.6 2.9e-30 105.1 3.9 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EDN10235.1 - 0.04 14.1 0.1 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Small acidic protein family Metallophos PF00149.23 EDN10236.1 - 2.8e-06 26.8 0.1 7.2e-06 25.5 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDN10236.1 - 0.00036 20.4 0.1 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_20 PF00728.17 EDN10237.1 - 5.9e-58 196.7 0.0 8.2e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EDN10237.1 - 1.2e-22 80.8 0.0 2.1e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EDN10237.1 - 2.4e-05 24.8 0.0 4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DOCK-C2 PF14429.1 EDN10238.1 - 3.4e-27 95.2 0.0 1.1e-26 93.6 0.0 1.9 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EDN10238.1 - 5.1e-14 51.9 0.0 1.4e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis Sec3_C PF09763.4 EDN10239.1 - 5.8e-79 266.0 0.1 6.5e-79 265.8 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3_C PF09763.4 EDN10240.1 - 2.7e-80 270.4 2.1 4.3e-80 269.7 1.5 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EDN10240.1 - 3.1e-31 107.0 0.5 1.6e-30 104.8 0.1 2.3 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH GETHR PF05671.6 EDN10240.1 - 0.13 11.4 10.7 0.011 14.8 3.9 1.8 2 0 0 2 2 2 0 GETHR pentapeptide repeat (5 copies) RNase_H PF00075.19 EDN10241.1 - 6e-15 55.7 0.0 9.7e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN10241.1 - 0.11 12.2 0.1 0.37 10.5 0.1 1.9 1 1 0 1 1 1 0 Reverse transcriptase-like DUF1729 PF08354.5 EDN10242.1 - 0.19 11.5 0.6 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) RVT_1 PF00078.22 EDN10244.1 - 3.4e-19 69.0 0.0 8e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FlxA PF14282.1 EDN10244.1 - 3.8 7.4 11.7 1.6 8.6 2.8 2.5 2 0 0 2 2 2 0 FlxA-like protein DDE_1 PF03184.14 EDN10246.1 - 4.9e-22 78.1 0.0 1.1e-15 57.4 0.0 2.4 1 1 1 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN10246.1 - 5e-12 45.4 0.0 4.5e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN10246.1 - 1.8e-10 40.2 0.2 3.4e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EDN10246.1 - 0.056 13.4 0.0 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Fic PF02661.13 EDN10247.1 - 4.2e-10 40.1 0.1 7.9e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Fic/DOC family RTC4 PF14474.1 EDN10248.1 - 5.7e-13 48.8 0.0 9.5e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain Myb_DNA-bind_6 PF13921.1 EDN10248.1 - 9e-06 25.7 3.5 9e-06 25.7 2.5 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN10248.1 - 0.00042 20.3 2.1 0.00093 19.2 1.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain UCH PF00443.24 EDN10251.1 - 1e-43 149.4 0.1 1e-43 149.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDN10251.1 - 2.4e-16 60.0 0.0 2.4e-16 60.0 0.0 2.2 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Yos1 PF08571.5 EDN10252.1 - 2e-19 69.4 0.1 6e-19 67.9 0.1 1.8 1 0 0 1 1 1 1 Yos1-like Dynamitin PF04912.9 EDN10253.1 - 2e-16 59.8 0.0 2.9e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Dynamitin GrpE PF01025.14 EDN10253.1 - 0.0045 16.5 0.3 0.0069 15.9 0.2 1.4 1 0 0 1 1 1 1 GrpE NUDE_C PF04880.8 EDN10253.1 - 0.011 16.1 3.8 0.042 14.2 2.6 1.9 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF3166 PF11365.3 EDN10253.1 - 0.014 15.8 0.2 0.026 14.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3166) Transposase_22 PF02994.9 EDN10253.1 - 0.017 13.6 0.1 0.022 13.2 0.0 1.1 1 0 0 1 1 1 0 L1 transposable element PVL_ORF50 PF07768.6 EDN10253.1 - 5.5 7.0 5.8 1.1e+02 2.7 4.0 2.2 1 1 0 1 1 1 0 PVL ORF-50-like family Aldedh PF00171.17 EDN10256.1 - 8e-121 403.5 2.1 6.1e-73 245.7 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 EDN10256.1 - 0.00025 19.8 0.0 0.00042 19.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Calreticulin PF00262.13 EDN10257.1 - 5.4e-166 551.7 25.9 4.6e-165 548.7 12.2 2.0 2 0 0 2 2 2 2 Calreticulin family Aldolase_II PF00596.16 EDN10258.1 - 9.1e-42 142.7 0.0 1.1e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PX PF00787.19 EDN10259.1 - 9.4e-25 86.6 0.1 2e-24 85.5 0.0 1.6 2 0 0 2 2 2 1 PX domain TcdB_N PF12918.2 EDN10261.1 - 0.07 13.2 1.3 0.21 11.6 0.9 1.9 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain 4HBT_2 PF13279.1 EDN10262.1 - 7.7e-24 84.4 0.0 1.4e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EDN10262.1 - 0.0045 17.0 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily Complex1_LYR_2 PF13233.1 EDN10263.1 - 4.6e-11 43.1 0.1 5e-11 42.9 0.1 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 EDN10263.1 - 4.4e-05 23.6 0.1 5.1e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EDN10263.1 - 6.5e-05 22.6 0.2 7.9e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Methyltransf_11 PF08241.7 EDN10264.1 - 4.4e-06 27.1 0.0 8.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN10264.1 - 1.3e-05 25.5 0.0 2.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN10264.1 - 0.001 18.8 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN10264.1 - 0.0056 15.8 0.0 0.0093 15.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EDN10264.1 - 0.031 13.8 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EDN10264.1 - 0.069 13.1 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EDN10264.1 - 0.074 13.6 0.0 0.22 12.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Exo_endo_phos PF03372.18 EDN10265.1 - 1.6e-21 77.3 0.1 2.9e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EDN10265.1 - 1.3e-14 53.4 6.3 1.6e-09 37.1 0.6 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDN10265.1 - 1.3e-10 40.9 12.1 8.9e-08 31.7 2.8 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EDN10265.1 - 8.5e-08 31.2 2.8 0.065 13.2 0.0 4.1 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 EDN10265.1 - 8.5e-06 25.1 7.7 0.18 12.1 0.0 4.3 4 0 0 4 4 4 3 Leucine rich repeat DUF1348 PF07080.6 EDN10266.1 - 2.7e-43 147.1 2.2 3.2e-43 146.9 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 EDN10266.1 - 0.00027 21.2 0.1 0.00034 20.9 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EDN10266.1 - 0.0051 17.0 0.1 0.0067 16.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) zf-CCHC_3 PF13917.1 EDN10266.1 - 0.15 11.8 0.6 0.3 10.8 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle FTA2 PF13095.1 EDN10267.1 - 3.2e-73 245.7 0.0 4.2e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 DUF2316 PF10078.4 EDN10267.1 - 0.031 14.2 0.4 0.06 13.3 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Hydrolase_4 PF12146.3 EDN10268.1 - 3.4e-18 65.2 0.0 6.7e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EDN10268.1 - 4.5e-11 43.0 0.1 6.4e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN10268.1 - 4.2e-10 39.5 0.0 6.5e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDN10268.1 - 0.0012 18.2 0.0 0.0074 15.7 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF1749 PF08538.5 EDN10268.1 - 0.022 13.6 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Chlorophyllase PF07224.6 EDN10268.1 - 0.028 13.2 0.2 0.12 11.1 0.2 1.9 1 1 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 EDN10268.1 - 0.1 11.4 0.0 0.23 10.2 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme PAF-AH_p_II PF03403.8 EDN10268.1 - 0.13 10.5 0.3 2.6 6.2 0.0 2.0 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II GCD14 PF08704.5 EDN10269.1 - 9.8e-06 25.2 0.0 0.012 15.1 0.0 2.4 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_28 PF02636.12 EDN10269.1 - 0.026 13.9 0.0 0.42 9.9 0.0 2.2 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Metallophos PF00149.23 EDN10270.1 - 1.4e-10 40.8 0.0 2.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDN10270.1 - 0.00017 21.4 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NAD_binding_6 PF08030.7 EDN10271.1 - 5.6e-06 26.3 0.0 0.00055 19.8 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EDN10271.1 - 6.8e-06 26.6 0.0 0.018 15.5 0.0 3.0 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain MARVEL PF01284.18 EDN10272.1 - 0.00054 19.8 0.2 0.00095 19.0 0.1 1.4 1 1 0 1 1 1 1 Membrane-associating domain Pmp3 PF01679.12 EDN10272.1 - 0.067 12.9 7.1 0.13 11.9 0.8 2.7 2 0 0 2 2 2 0 Proteolipid membrane potential modulator CcmD PF04995.9 EDN10272.1 - 1.8 8.3 4.9 9.6 6.0 3.4 2.2 1 1 0 1 1 1 0 Heme exporter protein D (CcmD) E1-E2_ATPase PF00122.15 EDN10273.1 - 3.3e-52 176.8 0.3 7.8e-52 175.5 0.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EDN10273.1 - 2.8e-44 152.0 0.1 4.2e-44 151.5 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDN10273.1 - 1.7e-14 54.4 0.0 3.8e-14 53.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDN10273.1 - 0.00045 19.8 0.3 0.0014 18.2 0.1 1.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase PCI PF01399.22 EDN10274.1 - 4.1e-07 30.2 0.0 6.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 PCI domain Serglycin PF04360.7 EDN10274.1 - 8.3 6.1 10.1 0.26 10.9 1.6 2.4 3 0 0 3 3 3 0 Serglycin Bromodomain PF00439.20 EDN10276.1 - 1.8e-25 88.6 0.6 4.1e-25 87.5 0.4 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EDN10276.1 - 0.0013 18.8 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN10276.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Rad1 PF02144.11 EDN10277.1 - 3.8e-98 327.6 0.0 5e-98 327.2 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 AAA_23 PF13476.1 EDN10278.1 - 2.7e-12 47.4 1.4 2.7e-12 47.4 0.9 7.5 2 1 3 5 5 5 1 AAA domain SbcCD_C PF13558.1 EDN10278.1 - 8e-12 44.9 0.0 2.9e-11 43.1 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EDN10278.1 - 3.9e-05 22.3 114.0 4e-05 22.3 20.3 5.5 1 1 4 5 5 5 3 AAA domain AAA_21 PF13304.1 EDN10278.1 - 0.00039 20.4 0.0 0.00039 20.4 0.0 2.9 3 1 1 4 4 4 1 AAA domain DUF948 PF06103.6 EDN10278.1 - 0.19 11.5 35.3 0.062 13.1 0.3 8.0 8 1 0 8 8 8 0 Bacterial protein of unknown function (DUF948) GATA PF00320.22 EDN10279.1 - 9.6e-15 53.6 4.2 2.4e-14 52.3 2.9 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EDN10279.1 - 2.4e-12 46.7 0.0 4.3e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EDN10279.1 - 1e-07 32.2 0.0 2.4e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.1 EDN10279.1 - 1.6e-07 31.2 0.0 2.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EDN10279.1 - 2.2e-07 30.6 0.0 4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 PAS fold PPP4R2 PF09184.6 EDN10280.1 - 4e-10 39.7 3.0 6.1e-10 39.1 0.0 2.4 2 1 0 2 2 2 1 PPP4R2 DUF155 PF02582.9 EDN10282.1 - 5.3e-59 199.0 0.0 7.8e-59 198.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 AMP-binding PF00501.23 EDN10283.1 - 1.2e-26 93.0 0.8 1.9e-25 89.1 0.6 2.0 1 1 0 1 1 1 1 AMP-binding enzyme zf-H2C2_2 PF13465.1 EDN10284.1 - 3.9e-15 55.2 7.5 4.9e-07 29.7 0.4 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EDN10284.1 - 9.1e-14 50.8 10.2 5.2e-05 23.3 0.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN10284.1 - 4.5e-07 29.7 8.6 0.0037 17.4 0.5 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDN10284.1 - 0.00091 19.2 1.6 0.59 10.3 0.0 3.6 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDN10284.1 - 0.034 14.3 2.9 0.23 11.7 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EDN10284.1 - 0.036 13.9 5.6 7.6 6.5 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger ADK_lid PF05191.9 EDN10284.1 - 0.075 12.7 2.4 25 4.6 0.1 3.7 3 0 0 3 3 3 0 Adenylate kinase, active site lid XPA_N PF01286.13 EDN10284.1 - 0.12 12.0 7.9 0.11 12.1 0.4 2.8 3 0 0 3 3 3 0 XPA protein N-terminal Zn-ribbon_8 PF09723.5 EDN10284.1 - 0.32 10.9 5.8 20 5.2 0.1 3.0 1 1 2 3 3 3 0 Zinc ribbon domain E1-E2_ATPase PF00122.15 EDN10286.1 - 2.5e-54 183.7 2.8 5e-54 182.7 1.9 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EDN10286.1 - 8.3e-29 101.5 0.0 4.9e-27 95.7 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDN10286.1 - 1.6e-20 72.8 0.0 3.5e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EDN10286.1 - 4.3e-14 51.7 0.0 1.3e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EDN10286.1 - 8.7e-13 48.8 0.0 2.6e-12 47.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EDN10286.1 - 2.9e-11 43.2 2.5 5.8e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.7 EDN10286.1 - 1.5e-06 27.9 0.3 0.00023 20.8 0.4 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GCP5-Mod21 PF14609.1 EDN10286.1 - 0.062 11.4 0.9 0.092 10.8 0.6 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 zf-UBP PF02148.14 EDN10287.1 - 9.9e-20 70.4 4.6 2.9e-19 68.9 3.2 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EDN10287.1 - 3.2e-09 36.4 9.9 3.2e-09 36.4 6.9 2.4 2 0 0 2 2 2 1 Ring finger domain BRAP2 PF07576.7 EDN10287.1 - 0.00012 21.6 0.7 0.042 13.4 0.2 2.4 1 1 1 2 2 2 2 BRCA1-associated protein 2 zf-RING_5 PF14634.1 EDN10287.1 - 0.00017 21.2 7.7 0.00017 21.2 5.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDN10287.1 - 0.00089 18.8 8.8 0.00089 18.8 6.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN10287.1 - 0.0009 19.2 9.7 0.0009 19.2 6.7 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN10287.1 - 0.0009 18.8 5.7 0.0009 18.8 4.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDN10287.1 - 0.0017 18.0 4.9 0.019 14.7 3.4 2.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EDN10287.1 - 0.0021 18.1 5.7 0.0021 18.1 3.9 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EDN10287.1 - 0.0087 15.8 5.1 0.021 14.6 3.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EDN10287.1 - 0.012 15.3 3.5 0.012 15.3 2.4 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein ApoO PF09769.4 EDN10287.1 - 0.06 13.0 2.3 0.47 10.1 0.1 2.4 2 0 0 2 2 2 0 Apolipoprotein O Baculo_RING PF05883.6 EDN10287.1 - 0.21 11.4 4.9 0.69 9.7 3.3 1.8 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain ubiquitin PF00240.18 EDN10288.1 - 3.1e-134 436.5 22.3 1.1e-33 114.4 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EDN10288.1 - 1.1e-77 255.7 21.3 4.3e-19 67.9 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDN10288.1 - 5.1e-24 84.3 10.1 0.00015 21.9 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDN10288.1 - 2.8e-21 75.9 0.9 0.00079 19.1 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EDN10288.1 - 4.9e-14 52.1 2.6 0.12 12.2 0.0 4.9 4 3 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDN10288.1 - 7.1e-14 51.7 2.1 0.06 13.5 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EDN10288.1 - 9.8e-11 41.5 0.0 1.5 8.9 0.0 4.9 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 EDN10288.1 - 6.3e-06 25.4 0.6 2 7.5 0.0 3.2 3 0 0 3 3 3 3 RNA methyltransferase TUG-UBL1 PF11470.3 EDN10288.1 - 2e-05 24.4 5.3 3.6 7.5 0.0 4.2 4 0 0 4 4 4 3 GLUT4 regulating protein TUG Plexin_cytopl PF08337.7 EDN10288.1 - 0.00053 18.4 13.9 0.67 8.1 0.2 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain FlgD_ig PF13860.1 EDN10288.1 - 0.0006 19.4 5.2 14 5.5 0.0 4.2 4 0 0 4 4 4 0 FlgD Ig-like domain ACT_4 PF13291.1 EDN10288.1 - 0.0027 17.9 0.8 30 5.0 0.0 4.1 4 0 0 4 4 4 0 ACT domain DUF3861 PF12977.2 EDN10288.1 - 0.0076 16.3 5.1 14 5.8 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Big_3_3 PF13750.1 EDN10288.1 - 0.02 14.3 0.1 51 3.2 0.0 3.5 3 1 0 4 4 4 0 Bacterial Ig-like domain (group 3) CTDII PF01556.13 EDN10288.1 - 0.043 13.7 13.6 8 6.4 0.2 4.3 1 1 3 4 4 4 0 DnaJ C terminal domain Brix PF04427.13 EDN10288.1 - 0.047 13.3 0.3 60 3.2 0.0 3.7 1 1 2 4 4 4 0 Brix domain GABP-alpha PF11620.3 EDN10288.1 - 0.062 13.2 7.7 44 4.1 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain Tash_PEST PF07708.6 EDN10288.1 - 0.23 11.4 21.2 3.5 7.7 1.2 4.3 4 0 0 4 4 4 0 Tash protein PEST motif FERM_N PF09379.5 EDN10288.1 - 0.56 10.2 12.8 42 4.2 0.1 5.8 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 EDN10288.1 - 0.65 9.9 7.1 57 3.7 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Myosin_N PF02736.14 EDN10288.1 - 2.7 7.7 9.3 84 2.9 0.1 4.7 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain CDC48_2 PF02933.12 EDN10288.1 - 3 7.5 12.5 18 5.0 0.2 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 Prenyltrans PF00432.16 EDN10290.1 - 1.2e-21 75.9 24.0 1.2e-10 40.7 0.0 5.5 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EDN10290.1 - 1.9e-20 73.3 1.5 1.4e-11 44.7 0.1 3.4 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EDN10290.1 - 0.014 15.3 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Prenyltransferase-like DUF4448 PF14610.1 EDN10294.1 - 2.9e-46 157.3 0.0 3.9e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) HMGL-like PF00682.14 EDN10295.1 - 2.5e-72 243.3 0.5 3.6e-72 242.8 0.3 1.2 1 0 0 1 1 1 1 HMGL-like Hpt PF01627.18 EDN10296.1 - 3.5e-12 46.1 0.0 4.1e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Hpt domain SseC PF04888.7 EDN10297.1 - 0.0086 15.4 2.6 0.012 14.9 1.8 1.1 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family BAF PF02961.9 EDN10297.1 - 0.079 13.2 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Barrier to autointegration factor SART-1 PF03343.8 EDN10298.1 - 1.9e-179 597.9 61.3 1.9e-179 597.9 42.5 1.6 2 0 0 2 2 2 1 SART-1 family PTH2 PF01981.11 EDN10298.1 - 2.4e-20 72.3 0.0 2.4e-20 72.3 0.0 2.6 2 1 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 Ribosomal_60s PF00428.14 EDN10298.1 - 2.9 8.3 12.7 0.17 12.3 0.7 3.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Aminotran_1_2 PF00155.16 EDN10299.1 - 4.8e-95 318.5 0.0 5.5e-95 318.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 EDN10300.1 - 3.5e-18 65.2 0.0 7e-18 64.2 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EDN10300.1 - 2.7e-05 23.0 0.0 5.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EDN10300.1 - 0.00067 18.8 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EDN10300.1 - 0.041 12.1 0.0 0.063 11.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EDN10300.1 - 0.044 12.9 0.0 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Resolvase PF00239.16 EDN10300.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Resolvase, N terminal domain Ribosomal_L30 PF00327.15 EDN10301.1 - 4.2e-16 58.2 0.2 5.9e-16 57.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Sec6 PF06046.8 EDN10302.1 - 1.8e-175 584.2 13.2 1.8e-175 584.2 9.1 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 AKAP7_NLS PF10469.4 EDN10303.1 - 1.5e-16 60.7 0.0 3.2e-16 59.6 0.0 1.5 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Frataxin_Cyay PF01491.11 EDN10304.1 - 3.6e-21 74.9 0.0 5.1e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain RNHCP PF12647.2 EDN10304.1 - 0.074 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 RNHCP domain zf-CSL PF05207.8 EDN10305.1 - 2.3e-23 81.4 0.5 3e-23 81.0 0.3 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EDN10305.1 - 0.019 14.9 0.4 0.035 14.0 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain PH_6 PF15406.1 EDN10307.1 - 2.7e-35 120.7 1.7 2.7e-35 120.7 1.2 3.7 3 1 1 4 4 4 1 Pleckstrin homology domain PH PF00169.24 EDN10307.1 - 0.0013 18.9 0.4 0.0043 17.2 0.0 2.1 2 0 0 2 2 2 1 PH domain PNTB PF02233.11 EDN10309.1 - 5.9e-173 575.9 20.2 5.9e-173 575.9 14.0 1.8 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EDN10309.1 - 9.8e-52 174.9 0.3 1.9e-51 173.9 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EDN10309.1 - 8.8e-46 155.2 0.0 2.9e-45 153.5 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EDN10309.1 - 3.2e-30 104.1 4.4 3.2e-30 104.1 3.1 5.1 4 2 1 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EDN10309.1 - 0.00099 18.3 3.2 1 8.4 0.0 3.8 4 0 0 4 4 4 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 EDN10309.1 - 0.045 13.3 0.1 0.21 11.1 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain TPP_enzyme_M PF00205.17 EDN10309.1 - 0.11 12.2 0.7 0.99 9.1 0.3 2.8 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Shikimate_DH PF01488.15 EDN10309.1 - 2.3 8.3 5.9 6.6 6.8 0.1 3.3 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase bZIP_1 PF00170.16 EDN10311.1 - 3.8e-07 29.9 5.6 7.7e-07 28.9 3.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EDN10311.1 - 7.3e-06 25.7 8.5 1.3e-05 24.9 5.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Lipase_GDSL_2 PF13472.1 EDN10312.1 - 3.4e-14 53.3 0.0 4.6e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EDN10312.1 - 0.00045 20.1 0.0 0.00075 19.3 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DIOX_N PF14226.1 EDN10313.1 - 2e-27 96.0 0.0 3.3e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EDN10313.1 - 4.1e-13 49.4 0.0 6.9e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RVT_2 PF07727.9 EDN10314.1 - 9.7e-59 198.3 0.0 1.4e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EDN10314.1 - 0.00013 21.6 4.1 0.00027 20.6 2.8 1.6 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.1 EDN10314.1 - 0.001 18.6 0.3 0.0032 17.0 0.0 2.0 2 0 0 2 2 2 1 GAG-pre-integrase domain rve PF00665.21 EDN10314.1 - 0.01 15.9 0.1 0.63 10.1 0.0 2.5 1 1 1 2 2 2 0 Integrase core domain DUF3435 PF11917.3 EDN10315.1 - 4.3e-144 480.2 9.3 8.7e-90 301.4 3.9 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF3435) bZIP_2 PF07716.10 EDN10315.1 - 8.7e-06 25.4 9.9 8.7e-06 25.4 6.8 3.1 3 0 0 3 3 3 1 Basic region leucine zipper Phage_integrase PF00589.17 EDN10315.1 - 5.5e-05 22.9 0.3 0.0066 16.1 0.0 2.6 2 0 0 2 2 2 1 Phage integrase family bZIP_1 PF00170.16 EDN10315.1 - 0.012 15.5 11.6 0.012 15.5 8.1 3.2 3 0 0 3 3 3 0 bZIP transcription factor OmpH PF03938.9 EDN10315.1 - 0.68 9.8 0.0 0.68 9.8 0.0 3.8 4 1 0 4 4 4 0 Outer membrane protein (OmpH-like) Mito_carr PF00153.22 EDN10317.1 - 1.9e-59 197.3 1.2 7.5e-21 73.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Spore_coat_CotO PF14153.1 EDN10319.1 - 0.05 13.0 12.7 0.052 12.9 8.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Ycf1 PF05758.7 EDN10319.1 - 0.097 10.3 11.9 0.098 10.3 8.2 1.1 1 0 0 1 1 1 0 Ycf1 EVC2_like PF12297.3 EDN10319.1 - 0.62 8.6 17.5 0.83 8.2 12.1 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein SAPS PF04499.10 EDN10319.1 - 1 7.8 7.4 1.3 7.5 5.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Dynactin_p62 PF05502.8 EDN10319.1 - 1.9 7.1 6.4 2.4 6.8 4.4 1.0 1 0 0 1 1 1 0 Dynactin p62 family Hid1 PF12722.2 EDN10319.1 - 2.4 5.7 7.3 2.9 5.4 5.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Vfa1 PF08432.5 EDN10319.1 - 3.3 7.6 19.7 6.3 6.7 13.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peptidase_S46 PF10459.4 EDN10319.1 - 4.8 5.4 12.0 6.2 5.1 8.3 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF2115 PF09888.4 EDN10319.1 - 6.9 6.7 8.4 4.7 7.2 4.6 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Prefoldin_2 PF01920.15 EDN10320.1 - 2.6e-19 68.9 3.7 3.2e-19 68.6 2.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit BLOC1_2 PF10046.4 EDN10320.1 - 0.0011 19.0 2.5 0.0057 16.7 0.1 2.2 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pox_A_type_inc PF04508.7 EDN10320.1 - 0.031 14.0 0.2 1 9.3 0.1 2.9 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat SF-assemblin PF06705.6 EDN10320.1 - 0.087 11.9 4.9 0.33 10.0 3.4 1.9 1 1 0 1 1 1 0 SF-assemblin/beta giardin YjcZ PF13990.1 EDN10320.1 - 0.29 10.2 2.9 0.77 8.8 2.0 1.7 1 1 0 1 1 1 0 YjcZ-like protein Fib_alpha PF08702.5 EDN10320.1 - 0.8 9.8 6.6 2.9 7.9 0.2 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 EDN10320.1 - 2.3 8.1 6.7 0.28 11.0 0.6 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.6 EDN10320.1 - 3.2 7.4 6.6 13 5.5 0.4 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FlxA PF14282.1 EDN10320.1 - 6.6 6.7 10.1 4.5 7.2 2.6 2.2 1 1 0 2 2 2 0 FlxA-like protein DUF2306 PF10067.4 EDN10321.1 - 0.0025 17.9 0.1 0.0025 17.9 0.1 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF4405 PF14358.1 EDN10321.1 - 0.051 13.7 6.3 5.5 7.2 2.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Ceramidase PF05875.7 EDN10322.1 - 1.1e-83 280.4 16.4 8.6e-81 270.9 7.2 2.1 1 1 1 2 2 2 2 Ceramidase DUF788 PF05620.6 EDN10322.1 - 0.099 12.4 3.1 0.11 12.3 1.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF788) DUF2207 PF09972.4 EDN10322.1 - 0.23 9.9 0.8 0.3 9.6 0.1 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Abhydrolase_6 PF12697.2 EDN10323.1 - 8.1e-25 88.0 0.8 3.6e-24 85.9 0.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN10323.1 - 0.00012 21.8 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN10323.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Poty_PP PF08440.5 EDN10323.1 - 0.34 9.9 0.9 0.72 8.8 0.0 1.8 2 0 0 2 2 2 0 Potyviridae polyprotein DJ-1_PfpI PF01965.19 EDN10325.1 - 5.3e-22 77.8 0.3 1.3e-21 76.5 0.2 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EDN10325.1 - 1.1e-16 60.0 0.1 2.5e-16 58.9 0.0 1.6 2 0 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family ADH_N PF08240.7 EDN10326.1 - 5.4e-21 74.3 3.1 1.1e-20 73.4 2.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN10326.1 - 4.2e-14 52.2 0.0 7.8e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EDN10326.1 - 0.00061 18.9 0.1 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EDN10326.1 - 0.019 14.5 0.1 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.20 EDN10327.1 - 2.3e-07 30.2 0.0 1.5e-05 24.3 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain PTCB-BRCT PF12738.2 EDN10328.1 - 1.2e-24 85.9 1.8 5.8e-20 70.9 0.4 3.5 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.21 EDN10328.1 - 2.9e-17 62.5 0.1 1.1e-08 35.0 0.1 4.7 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain ESCRT-II PF05871.7 EDN10329.1 - 4.1e-53 179.0 0.0 6.2e-53 178.4 0.0 1.3 1 0 0 1 1 1 1 ESCRT-II complex subunit DDE_1 PF03184.14 EDN10330.1 - 9e-51 172.0 0.0 2e-50 170.9 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN10330.1 - 3.8e-06 26.7 0.0 7.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_4 PF02390.12 EDN10331.1 - 3e-47 160.2 0.0 3.9e-35 120.6 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EDN10331.1 - 5.6e-06 26.9 0.0 8.9e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN10331.1 - 0.00033 20.6 0.0 0.00066 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN10331.1 - 0.0058 16.0 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EDN10331.1 - 0.009 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF4191 PF13829.1 EDN10331.1 - 0.02 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) FmrO PF07091.6 EDN10331.1 - 0.024 13.6 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_31 PF13847.1 EDN10331.1 - 0.04 13.5 0.0 0.096 12.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EDN10331.1 - 0.044 14.2 0.0 0.88 10.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EDN10331.1 - 0.054 13.9 0.0 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain PAT1 PF09770.4 EDN10331.1 - 0.42 8.7 3.7 0.72 8.0 2.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LIM PF00412.17 EDN10332.1 - 5.5e-28 96.8 27.4 2.3e-10 40.3 1.1 4.0 3 1 0 3 3 3 3 LIM domain Zn_ribbon_recom PF13408.1 EDN10332.1 - 0.17 12.1 0.2 0.17 12.1 0.1 3.2 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain DUF2321 PF10083.4 EDN10332.1 - 4.4 6.7 10.1 0.035 13.6 0.8 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) MFS_1 PF07690.11 EDN10333.1 - 2.5e-15 56.0 41.0 1.6e-14 53.4 28.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Med25_SD1 PF11235.3 EDN10333.1 - 0.036 14.3 3.2 0.075 13.3 2.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 RNB PF00773.14 EDN10334.1 - 2.3e-14 53.4 0.2 3.1e-14 52.9 0.1 1.2 1 0 0 1 1 1 1 RNB domain RNB PF00773.14 EDN10335.1 - 5.9e-46 157.2 0.0 1e-45 156.4 0.0 1.4 1 0 0 1 1 1 1 RNB domain ESSS PF10183.4 EDN10337.1 - 1e-28 99.7 0.1 1.2e-28 99.5 0.1 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ATP-synt_E PF05680.7 EDN10337.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase E chain Acyl-CoA_ox_N PF14749.1 EDN10338.1 - 1.9e-16 60.5 0.7 2.3e-16 60.2 0.5 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Sec20 PF03908.8 EDN10338.1 - 0.0082 15.8 2.3 0.022 14.4 0.8 2.0 1 1 1 2 2 2 1 Sec20 DUF1835 PF08874.5 EDN10338.1 - 0.082 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1835) AIP3 PF03915.8 EDN10340.1 - 4.1e-118 394.9 1.2 8.1e-118 394.0 0.0 2.1 2 1 0 2 2 2 1 Actin interacting protein 3 MCPsignal PF00015.16 EDN10340.1 - 0.0098 15.4 1.6 5.9 6.3 0.1 3.2 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain FliL PF03748.9 EDN10340.1 - 0.037 14.0 0.2 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL CAS_CSE1 PF03378.10 EDN10340.1 - 0.24 9.6 0.3 0.5 8.5 0.2 1.4 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus DUF552 PF04472.7 EDN10340.1 - 0.35 10.8 1.4 0.48 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF552) SM-ATX PF14438.1 EDN10342.1 - 3.2e-16 58.9 0.0 5.6e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain LsmAD PF06741.8 EDN10342.1 - 4.8e-11 42.5 0.2 9.8e-11 41.6 0.2 1.5 1 0 0 1 1 1 1 LsmAD domain HEAT PF02985.17 EDN10345.1 - 2e-07 30.4 1.2 0.063 13.3 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EDN10345.1 - 3.5e-05 24.1 0.1 0.23 11.9 0.0 3.2 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.1 EDN10345.1 - 0.0014 18.8 0.1 0.12 12.6 0.1 3.2 1 1 1 2 2 2 1 HEAT repeats Pkinase_Tyr PF07714.12 EDN10345.1 - 0.0089 15.1 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Adaptin_N PF01602.15 EDN10345.1 - 0.099 10.9 0.0 0.18 10.0 0.0 1.4 1 1 0 1 1 1 0 Adaptin N terminal region Kinase-like PF14531.1 EDN10345.1 - 0.16 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Macoilin PF09726.4 EDN10348.1 - 0.0035 15.6 29.1 0.0045 15.3 20.2 1.1 1 0 0 1 1 1 1 Transmembrane protein DUF4407 PF14362.1 EDN10348.1 - 0.58 9.0 18.3 0.89 8.4 12.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliT PF05400.8 EDN10348.1 - 0.78 10.1 15.4 0.19 12.1 0.9 2.8 2 0 0 2 2 2 0 Flagellar protein FliT Rootletin PF15035.1 EDN10348.1 - 4.2 7.3 25.4 0.74 9.7 5.9 2.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Chorion_2 PF03964.10 EDN10348.1 - 4.3 7.9 16.0 1.1 9.8 7.4 2.7 2 1 0 2 2 2 0 Chorion family 2 Borrelia_P83 PF05262.6 EDN10348.1 - 4.5 5.4 17.2 7.1 4.7 11.9 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2046 PF09755.4 EDN10348.1 - 4.6 6.0 26.4 0.11 11.3 3.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) adh_short PF00106.20 EDN10349.1 - 1.4e-22 80.4 0.1 2e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN10349.1 - 2.8e-17 63.3 0.0 3.6e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN10349.1 - 2.4e-05 24.0 0.0 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 KR domain WD40 PF00400.27 EDN10351.1 - 2e-44 147.8 17.2 4.8e-12 45.2 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EDN10351.1 - 4.2e-08 31.8 3.4 0.083 11.0 0.1 4.9 4 1 1 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EDN10351.1 - 0.012 15.3 0.4 0.15 11.7 0.0 2.6 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 EDN10351.1 - 0.016 14.4 0.2 5.5 6.1 0.0 3.1 2 1 1 3 3 3 0 TUP1-like enhancer of split DUF3312 PF11768.3 EDN10351.1 - 0.042 12.0 0.0 0.065 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Tctex-1 PF03645.8 EDN10352.1 - 1.3e-34 118.0 0.0 1.6e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family CFEM PF05730.6 EDN10355.1 - 0.11 12.3 5.6 0.26 11.1 3.8 1.7 1 1 0 1 1 1 0 CFEM domain HECT PF00632.20 EDN10356.1 - 2e-94 316.2 0.1 2.9e-94 315.8 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EDN10356.1 - 5.6e-33 112.4 20.4 4.5e-11 42.3 2.6 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EDN10356.1 - 3.1e-14 52.5 0.0 7.1e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF793 PF05633.6 EDN10358.1 - 0.11 11.1 0.2 0.13 10.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Aminotran_5 PF00266.14 EDN10359.1 - 1.2e-09 37.3 0.0 1.6e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF2360 PF10152.4 EDN10361.1 - 0.25 11.6 4.9 0.36 11.0 3.4 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Myosin_head PF00063.16 EDN10362.1 - 9.2e-160 532.9 1.3 2.6e-159 531.4 0.9 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EDN10362.1 - 1.2e-33 116.1 0.0 2e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Myosin tail IQ PF00612.22 EDN10362.1 - 0.0035 16.8 8.4 0.27 10.9 0.7 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif OPA3 PF07047.7 EDN10363.1 - 6.6e-14 51.8 1.5 1.9e-13 50.3 1.0 1.6 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) COX16 PF14138.1 EDN10363.1 - 6.7 6.9 7.6 1.8 8.8 0.5 2.7 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Pkinase PF00069.20 EDN10364.1 - 4.7e-58 196.3 0.1 2.6e-57 193.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN10364.1 - 1.9e-36 125.5 0.0 3.5e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EDN10364.1 - 7.6e-07 29.0 0.2 0.061 13.2 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EDN10364.1 - 0.0054 15.7 0.0 0.014 14.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EDN10364.1 - 0.053 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2-Hacid_dh_C PF02826.14 EDN10365.1 - 1.4e-38 131.8 0.0 2.6e-26 91.8 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.14 EDN10365.1 - 0.048 12.3 0.0 0.065 11.8 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Gp_dh_N PF00044.19 EDN10365.1 - 0.05 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EDN10365.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDN10365.1 - 0.12 11.8 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain RVT_1 PF00078.22 EDN10366.1 - 1.3e-26 93.3 0.0 2.5e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN10366.1 - 6.1e-05 22.6 0.0 0.00019 21.0 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF3381 PF11861.3 EDN10367.1 - 0.028 13.9 4.2 2.4 7.6 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Nucleoplasmin PF03066.10 EDN10367.1 - 0.036 13.6 5.5 0.06 12.8 3.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 EDN10367.1 - 0.039 12.4 5.1 0.033 12.7 3.5 1.1 1 0 0 1 1 1 0 Daxx Family DUF4246 PF14033.1 EDN10367.1 - 0.15 10.6 1.9 0.16 10.5 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) TRAP_alpha PF03896.11 EDN10367.1 - 0.19 10.7 2.7 0.22 10.4 1.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PBP1_TM PF14812.1 EDN10367.1 - 0.5 10.7 5.5 1.1 9.5 3.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 EDN10367.1 - 0.57 9.8 3.0 0.77 9.4 2.1 1.2 1 0 0 1 1 1 0 FAM176 family HSP90 PF00183.13 EDN10367.1 - 1.8 6.8 7.3 2.6 6.3 5.0 1.2 1 0 0 1 1 1 0 Hsp90 protein NESP55 PF06390.7 EDN10367.1 - 5.4 6.3 18.4 0.43 9.9 0.9 2.1 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Nucleo_P87 PF07267.6 EDN10367.1 - 5.8 5.4 6.6 7.3 5.1 4.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2985 PF11204.3 EDN10368.1 - 1.1e-37 127.6 1.8 1.7e-37 127.0 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Ribosomal_L24e PF01246.15 EDN10372.1 - 7e-28 96.3 3.1 1.7e-27 95.0 2.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 EDN10372.1 - 1.5 8.5 6.8 3.3 7.4 4.5 1.8 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DnaJ PF00226.26 EDN10373.1 - 9.3e-08 31.6 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EDN10373.1 - 1.1e-07 31.7 0.2 1.6e-07 31.1 0.2 1.5 1 1 0 1 1 1 1 Pam16 CRA PF06589.6 EDN10373.1 - 0.061 12.6 0.6 0.08 12.2 0.3 1.3 1 1 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF3918 PF13056.1 EDN10373.1 - 0.42 9.9 5.4 0.41 10.0 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3918) G_glu_transpept PF01019.16 EDN10374.1 - 2.8e-131 438.5 0.0 3.4e-131 438.2 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase TPMT PF05724.6 EDN10377.1 - 1.4e-15 57.3 0.4 7e-14 51.7 0.3 2.0 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 EDN10377.1 - 1.1e-05 25.9 0.0 1.8e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN10377.1 - 0.0002 21.3 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN10377.1 - 0.0028 17.9 0.0 0.0042 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN10377.1 - 0.0045 16.5 0.1 0.013 15.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EDN10377.1 - 0.023 14.8 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase N2227 PF07942.7 EDN10377.1 - 0.025 13.5 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein Methyltransf_11 PF08241.7 EDN10377.1 - 0.027 14.9 0.0 0.043 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EDN10377.1 - 0.034 13.8 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EDN10377.1 - 0.084 12.0 0.1 0.16 11.1 0.0 1.4 2 0 0 2 2 2 0 Tellurite resistance protein TehB OTU PF02338.14 EDN10378.1 - 1.2e-17 64.6 0.1 5.6e-17 62.4 0.0 2.2 3 1 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EDN10378.1 - 2.9e-08 33.3 0.0 2.6e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain NfI_DNAbd_pre-N PF10524.4 EDN10378.1 - 0.00076 19.0 0.9 0.032 13.8 0.0 2.4 2 0 0 2 2 2 1 Nuclear factor I protein pre-N-terminus Cep57_MT_bd PF06657.8 EDN10378.1 - 0.22 11.4 3.2 0.5 10.3 2.2 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 adh_short_C2 PF13561.1 EDN10379.1 - 7.6e-19 68.4 0.0 2e-14 53.9 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN10379.1 - 1.9e-08 34.4 0.0 2.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN10379.1 - 6e-05 22.7 0.0 8.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Eclosion PF04736.7 EDN10379.1 - 0.092 12.2 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Eclosion hormone Phage_fiber_2 PF03406.8 EDN10379.1 - 0.14 11.7 0.5 0.42 10.2 0.1 1.9 2 0 0 2 2 2 0 Phage tail fibre repeat Trehalase PF01204.13 EDN10380.1 - 3.5e-147 491.1 0.0 1.6e-131 439.4 0.0 2.1 1 1 1 2 2 2 2 Trehalase Trehalase_Ca-bi PF07492.6 EDN10380.1 - 2.2e-17 62.0 0.2 3.7e-17 61.3 0.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.16 EDN10381.1 - 5.9e-179 595.6 14.8 7.6e-146 486.3 0.4 3.0 1 1 1 2 2 2 2 Isocitrate lyase family HNH_2 PF13391.1 EDN10383.1 - 0.0013 18.4 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Fungal_trans PF04082.13 EDN10384.1 - 4.8e-21 74.7 2.8 2e-18 66.1 1.4 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Pkinase PF00069.20 EDN10386.1 - 6.7e-70 235.2 0.0 8.5e-70 234.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN10386.1 - 2.8e-30 105.2 0.0 4.1e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN10386.1 - 0.052 13.2 0.1 0.052 13.2 0.1 2.2 2 2 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EDN10386.1 - 0.079 12.0 0.0 0.22 10.5 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans PF04082.13 EDN10387.1 - 1.1e-09 37.6 1.0 1.5e-09 37.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Aldose_epim PF01263.15 EDN10389.1 - 1.8e-20 73.2 0.1 5.8e-12 45.3 0.0 2.0 2 0 0 2 2 2 2 Aldose 1-epimerase MFS_1 PF07690.11 EDN10390.1 - 4.7e-26 91.3 19.1 4.7e-26 91.3 13.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DAHP_synth_2 PF01474.11 EDN10391.1 - 1.8e-174 580.2 0.0 2.2e-156 520.6 0.0 2.0 1 1 1 2 2 2 2 Class-II DAHP synthetase family LdpA_C PF12617.3 EDN10391.1 - 0.081 12.1 0.1 6 6.0 0.0 2.4 2 1 0 2 2 2 0 Iron-Sulfur binding protein C terminal PLA2_B PF01735.13 EDN10393.1 - 2.1e-198 659.4 0.1 2.5e-198 659.2 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PSD3 PF07626.6 EDN10393.1 - 0.076 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1587) DDE_1 PF03184.14 EDN10394.1 - 1.3e-50 171.5 0.0 2.3e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN10394.1 - 8e-12 44.7 0.0 6.4e-11 41.9 0.0 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN10394.1 - 2.4e-10 39.7 0.2 4.6e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EDN10394.1 - 0.076 13.0 0.0 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Piwi PF02171.12 EDN10395.1 - 9.9e-76 254.5 0.0 1.4e-75 254.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EDN10395.1 - 3.7e-11 42.4 0.0 2.3e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 PAZ domain Ribophorin_II PF05817.9 EDN10397.1 - 1.8e-13 49.6 2.2 3e-13 48.8 1.5 1.3 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II AT_hook PF02178.14 EDN10399.1 - 0.074 12.7 0.6 0.074 12.7 0.4 2.9 2 0 0 2 2 2 0 AT hook motif PAT1 PF09770.4 EDN10399.1 - 1.6 6.8 20.4 2 6.5 14.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 His_Phos_2 PF00328.17 EDN10400.1 - 6.2e-51 173.7 0.0 7.2e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) bZIP_2 PF07716.10 EDN10401.1 - 1.7e-05 24.5 9.8 2.7e-05 23.9 6.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EDN10401.1 - 0.13 12.5 6.9 0.17 12.1 3.8 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor bZIP_1 PF00170.16 EDN10401.1 - 0.62 10.0 8.8 1.1 9.2 6.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor Aldedh PF00171.17 EDN10402.1 - 1.6e-177 590.5 0.7 1.8e-177 590.3 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family B12-binding PF02310.14 EDN10402.1 - 0.035 13.9 0.2 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 B12 binding domain SpoIIAA-like PF11964.3 EDN10402.1 - 0.073 13.3 0.1 0.23 11.7 0.0 1.8 1 0 0 1 1 1 0 SpoIIAA-like DUF1487 PF07368.6 EDN10402.1 - 0.078 12.1 0.0 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF2188 PF09954.4 EDN10402.1 - 0.097 12.5 0.7 0.4 10.6 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Methyltransf_PK PF05891.7 EDN10403.1 - 2.6e-59 200.1 0.0 3.1e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 EDN10403.1 - 0.011 16.3 0.0 0.021 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain EVE PF01878.13 EDN10404.1 - 7.9e-49 165.3 0.3 3.9e-40 137.1 0.1 2.6 1 1 1 2 2 2 2 EVE domain PsbW PF07123.7 EDN10404.1 - 0.8 9.7 3.5 0.86 9.6 1.5 1.8 1 1 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) MFS_1 PF07690.11 EDN10405.1 - 3e-31 108.4 9.9 3.5e-31 108.2 6.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EDN10405.1 - 1.1e-09 37.0 2.7 1.4e-09 36.7 1.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EDN10405.1 - 5.1e-09 35.2 4.7 6.9e-09 34.7 3.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter AhpC-TSA PF00578.16 EDN10407.1 - 6.7e-30 103.3 0.0 9.2e-30 102.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EDN10407.1 - 3.4e-13 49.0 0.1 5.8e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EDN10407.1 - 2.5e-11 43.3 0.0 3.3e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin Kelch_3 PF13415.1 EDN10409.1 - 7.6e-06 25.9 4.2 0.0066 16.5 0.0 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.1 EDN10409.1 - 1.4e-05 24.7 1.0 0.45 10.3 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EDN10409.1 - 8.2e-05 22.6 0.3 0.38 11.0 0.0 3.4 3 0 0 3 3 3 2 Kelch motif BTB PF00651.26 EDN10409.1 - 0.00055 19.8 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain Kelch_2 PF07646.10 EDN10409.1 - 0.012 15.3 0.0 0.35 10.7 0.0 2.9 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.20 EDN10409.1 - 0.065 12.7 0.1 3.7 7.1 0.0 2.7 2 0 0 2 2 2 0 Kelch motif mRNA_triPase PF02940.10 EDN10410.1 - 1.6e-53 181.6 0.0 2.5e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain HTH_Mga PF08280.6 EDN10410.1 - 0.29 10.9 0.1 0.55 10.0 0.1 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Acyl_transf_3 PF01757.17 EDN10411.1 - 1.6e-25 89.7 32.5 1.9e-24 86.1 22.5 2.1 1 1 0 1 1 1 1 Acyltransferase family WD40 PF00400.27 EDN10412.1 - 7.9e-23 79.4 9.5 6e-08 32.2 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat CTP_transf_2 PF01467.21 EDN10413.1 - 0.016 15.3 4.5 0.5 10.4 3.1 2.6 1 1 0 1 1 1 0 Cytidylyltransferase Ribosomal_L30 PF00327.15 EDN10414.1 - 0.099 12.2 0.2 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e DHquinase_II PF01220.14 EDN10414.1 - 0.11 11.7 0.0 2 7.7 0.0 2.2 2 0 0 2 2 2 0 Dehydroquinase class II Zn_clus PF00172.13 EDN10415.1 - 2.5e-08 33.6 10.6 4.1e-08 33.0 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM18 PF14770.1 EDN10416.1 - 0.031 13.8 0.1 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 18 PQ-loop PF04193.9 EDN10417.1 - 4.2e-21 74.2 4.0 2e-11 43.2 0.6 2.5 2 0 0 2 2 2 2 PQ loop repeat Med8 PF10232.4 EDN10418.1 - 2.4e-45 154.8 0.0 2.9e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 MFS_1 PF07690.11 EDN10419.1 - 1.2e-22 80.1 19.5 1.6e-22 79.7 13.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EDN10419.1 - 0.022 13.1 12.5 0.16 10.2 1.1 3.3 2 1 1 3 3 3 0 MFS/sugar transport protein RskA PF10099.4 EDN10419.1 - 0.052 13.2 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Lpp-LpqN PF10738.4 EDN10420.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Probable lipoprotein LpqN APH PF01636.18 EDN10421.1 - 0.0029 17.3 3.6 0.26 10.9 0.0 3.0 3 1 0 3 3 3 2 Phosphotransferase enzyme family Parathyroid PF01279.12 EDN10421.1 - 0.089 13.4 1.3 0.34 11.5 0.0 2.2 2 1 0 2 2 2 0 Parathyroid hormone family DUF3336 PF11815.3 EDN10422.1 - 6.6e-42 142.4 0.7 1.9e-41 140.9 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EDN10422.1 - 1.4e-23 83.8 0.5 5e-23 82.0 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase Abhydrolase_6 PF12697.2 EDN10423.1 - 0.00064 19.6 0.1 0.0016 18.3 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN10423.1 - 0.0036 17.0 0.1 0.016 14.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF318 PF03773.8 EDN10423.1 - 0.013 14.5 0.2 0.02 13.8 0.2 1.2 1 0 0 1 1 1 0 Predicted permease Abhydrolase_1 PF00561.15 EDN10423.1 - 0.014 14.9 0.0 0.26 10.8 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Fib_alpha PF08702.5 EDN10424.1 - 1.2 9.2 7.8 0.13 12.3 0.7 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 EDN10424.1 - 1.6 7.8 5.0 0.65 9.1 1.1 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Seryl_tRNA_N PF02403.17 EDN10424.1 - 3.4 7.7 21.5 0.25 11.3 2.9 4.5 3 2 2 5 5 5 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 EDN10424.1 - 3.8 7.3 6.7 0.57 9.9 1.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) PC_rep PF01851.17 EDN10425.1 - 2.1e-35 118.9 18.0 4.7e-09 35.9 0.0 9.5 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EDN10425.1 - 4.1e-18 65.4 2.2 4.2e-12 46.1 0.0 4.8 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EDN10425.1 - 2e-08 33.6 0.1 1.4 9.2 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EDN10425.1 - 3.5e-06 27.3 5.1 5.4e-05 23.5 0.0 4.7 4 1 1 5 5 5 1 HEAT-like repeat HEAT_PBS PF03130.11 EDN10425.1 - 0.00029 21.0 0.4 5.2 7.8 0.0 4.8 4 0 0 4 4 4 2 PBS lyase HEAT-like repeat Acyl-CoA_dh_1 PF00441.19 EDN10426.1 - 1.4e-39 135.5 0.4 2e-39 135.0 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EDN10426.1 - 7.3e-20 70.2 0.1 1.3e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EDN10426.1 - 6.2e-16 57.9 0.1 1.2e-15 57.0 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EDN10426.1 - 2.3e-12 47.4 0.0 5.2e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EDN10426.1 - 4.2e-08 33.5 0.1 7.7e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Spt5-NGN PF03439.8 EDN10427.1 - 1.1e-25 89.1 0.0 2e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.2 EDN10427.1 - 6.2e-25 88.0 50.0 5.3e-23 81.7 26.0 3.7 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 EDN10427.1 - 2.8e-16 59.9 9.0 2.8e-16 59.9 6.3 4.1 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EDN10427.1 - 1.3e-12 46.9 11.7 0.0036 16.9 0.1 5.4 5 0 0 5 5 5 3 KOW motif CS PF04969.11 EDN10428.1 - 1.2e-10 41.7 0.2 6.6e-10 39.3 0.1 2.1 1 1 0 1 1 1 1 CS domain tRNA-synt_2 PF00152.15 EDN10429.1 - 2e-102 342.4 0.0 2.7e-102 342.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EDN10429.1 - 0.001 18.6 0.0 0.0027 17.3 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) FAD_binding_4 PF01565.18 EDN10430.1 - 0.0003 20.2 0.1 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain PEP_mutase PF13714.1 EDN10431.1 - 6.5e-62 208.8 0.1 7.4e-62 208.6 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase APH PF01636.18 EDN10432.1 - 4.4e-09 36.4 0.0 7.6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HNH_2 PF13391.1 EDN10432.1 - 6.6e-07 29.0 0.0 2.2e-05 24.1 0.0 2.6 3 0 0 3 3 3 1 HNH endonuclease Choline_kinase PF01633.15 EDN10432.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase GMC_oxred_N PF00732.14 EDN10433.1 - 1.5e-27 96.5 0.0 2.2e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EDN10433.1 - 7.7e-19 68.4 0.0 1.4e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase ABC_tran PF00005.22 EDN10434.1 - 1.2e-40 138.9 0.0 8.6e-23 81.1 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDN10434.1 - 7e-32 110.9 30.5 1.6e-20 73.7 8.8 3.4 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EDN10434.1 - 3.3e-11 42.8 1.8 8.7e-05 21.8 0.1 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDN10434.1 - 3.9e-05 23.0 0.7 0.11 12.0 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EDN10434.1 - 0.00013 21.9 0.2 0.12 12.3 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EDN10434.1 - 0.00014 21.2 0.0 0.28 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EDN10434.1 - 0.00019 21.5 0.0 0.93 9.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EDN10434.1 - 0.00029 21.2 0.7 0.013 15.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EDN10434.1 - 0.00055 19.4 0.2 0.87 8.9 0.1 2.6 2 1 0 2 2 2 2 AAA-like domain AAA_16 PF13191.1 EDN10434.1 - 0.00069 19.6 0.7 0.21 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EDN10434.1 - 0.00095 19.6 0.0 2.3 8.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EDN10434.1 - 0.00098 18.3 0.1 1.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 EDN10434.1 - 0.0038 16.1 0.1 0.87 8.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_21 PF13304.1 EDN10434.1 - 0.013 15.4 1.9 15 5.4 0.0 4.0 4 1 0 4 4 4 0 AAA domain Zeta_toxin PF06414.7 EDN10434.1 - 0.016 14.3 0.4 1.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.12 EDN10434.1 - 0.025 14.4 5.7 0.61 9.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 ArgK PF03308.11 EDN10434.1 - 0.037 12.8 0.0 0.079 11.7 0.0 1.5 1 0 0 1 1 1 0 ArgK protein MobB PF03205.9 EDN10434.1 - 0.052 13.2 0.6 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 EDN10434.1 - 0.12 11.4 0.0 4.4 6.3 0.0 2.4 2 0 0 2 2 2 0 AIG1 family FtsK_SpoIIIE PF01580.13 EDN10434.1 - 0.16 11.4 0.0 7.9 5.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EDN10434.1 - 1.4 9.7 2.9 13 6.6 0.0 3.2 2 1 0 2 2 2 0 AAA domain Sulf_transp PF04143.9 EDN10435.1 - 7.6e-09 35.4 7.0 7.6e-09 35.4 4.8 2.5 3 0 0 3 3 3 1 Sulphur transport DUF1600 PF07667.6 EDN10435.1 - 0.095 12.8 0.8 0.13 12.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) Peptidase_M28 PF04389.12 EDN10436.1 - 5.2e-32 111.0 0.0 8.9e-32 110.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M28 DUF1227 PF06777.6 EDN10436.1 - 0.18 11.4 0.0 1 9.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1227) Rhodanese PF00581.15 EDN10438.1 - 4.7e-06 26.9 0.0 7.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain MutS_V PF00488.16 EDN10439.1 - 1.2e-79 267.0 0.0 2e-79 266.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EDN10439.1 - 4.1e-53 180.2 0.1 8.8e-53 179.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EDN10439.1 - 4.9e-33 113.5 0.1 1.7e-32 111.8 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EDN10439.1 - 9.3e-17 60.9 0.3 2e-16 59.9 0.2 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EDN10439.1 - 5.8e-12 45.8 0.0 2.6e-11 43.7 0.0 2.2 1 1 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 EDN10439.1 - 0.00047 20.5 3.5 0.0021 18.4 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EDN10439.1 - 0.015 14.7 0.0 0.047 13.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EDN10439.1 - 0.093 12.6 0.2 0.093 12.6 0.1 2.5 3 0 0 3 3 3 0 AAA domain Filament PF00038.16 EDN10439.1 - 0.1 12.0 0.7 0.21 11.0 0.5 1.4 1 0 0 1 1 1 0 Intermediate filament protein tRNA-synt_1b PF00579.20 EDN10440.1 - 1.7e-66 224.3 0.0 2.2e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Acetyltransf_6 PF13480.1 EDN10440.1 - 0.006 16.5 0.1 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain S4 PF01479.20 EDN10440.1 - 0.04 13.3 0.5 0.15 11.4 0.0 2.2 3 0 0 3 3 3 0 S4 domain Raffinose_syn PF05691.7 EDN10441.1 - 8.6e-53 178.9 4.9 2e-45 154.6 0.8 2.6 1 1 1 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 EDN10441.1 - 1.3e-06 27.4 0.3 1.9e-06 26.8 0.2 1.2 1 0 0 1 1 1 1 Melibiase Aldedh PF00171.17 EDN10442.1 - 3.3e-161 536.7 0.2 3.8e-161 536.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EDN10442.1 - 0.054 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) DUF2263 PF10021.4 EDN10443.1 - 1e-27 96.9 0.0 1.7e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) RRN9 PF10680.4 EDN10444.1 - 4.5e-23 80.7 0.4 1.4e-22 79.1 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor Pescadillo_N PF06732.6 EDN10445.1 - 3.6e-113 377.4 0.1 3.6e-113 377.4 0.0 2.3 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 EDN10445.1 - 8e-08 32.3 0.0 8.4e-07 29.0 0.0 2.7 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Acetyltransf_1 PF00583.19 EDN10447.1 - 4.8e-14 52.1 0.3 8e-14 51.4 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EDN10447.1 - 0.00036 20.6 0.0 0.00067 19.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDN10447.1 - 0.00043 19.9 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EDN10447.1 - 0.0016 18.5 0.5 0.0027 17.8 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EDN10447.1 - 0.0098 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF591 PF04569.9 EDN10447.1 - 0.31 11.1 4.0 0.57 10.2 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function HIG_1_N PF04588.8 EDN10448.1 - 1.2e-21 76.2 0.0 1.6e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region OPA3 PF07047.7 EDN10448.1 - 0.0093 15.7 0.6 0.015 15.0 0.2 1.5 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) MAS20 PF02064.10 EDN10448.1 - 0.02 14.8 0.9 0.028 14.3 0.6 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor FAM176 PF14851.1 EDN10449.1 - 0.014 15.0 1.8 0.016 14.9 1.2 1.2 1 0 0 1 1 1 0 FAM176 family DUF3682 PF12446.3 EDN10449.1 - 0.052 13.8 6.7 0.065 13.5 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) IFT57 PF10498.4 EDN10449.1 - 0.093 11.4 1.6 0.094 11.4 1.1 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Ribosomal_60s PF00428.14 EDN10449.1 - 0.13 12.6 6.5 0.16 12.4 4.5 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF1510 PF07423.6 EDN10449.1 - 0.15 11.4 3.5 0.15 11.4 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) VID27 PF08553.5 EDN10449.1 - 0.15 10.2 2.5 0.14 10.4 1.7 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Myc_N PF01056.13 EDN10449.1 - 0.15 11.1 6.5 0.15 11.1 4.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region BSP_II PF05432.6 EDN10449.1 - 0.18 11.0 7.7 0.19 10.9 5.4 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Sigma70_ner PF04546.8 EDN10449.1 - 0.19 11.3 6.0 0.22 11.0 4.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 EDN10449.1 - 0.24 9.8 8.7 0.26 9.7 6.0 1.0 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 EDN10449.1 - 0.26 10.2 2.2 0.25 10.2 1.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.6 EDN10449.1 - 0.27 9.0 3.8 0.32 8.8 2.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleo_P87 PF07267.6 EDN10449.1 - 0.32 9.6 6.8 0.38 9.3 4.7 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RXT2_N PF08595.6 EDN10449.1 - 0.39 10.5 4.8 0.45 10.3 3.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_Ag35 PF03286.9 EDN10449.1 - 0.58 9.6 5.7 0.59 9.6 3.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP_sp32 PF07222.7 EDN10449.1 - 0.77 8.8 3.6 0.85 8.7 2.5 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CDC45 PF02724.9 EDN10449.1 - 1 7.3 3.7 0.98 7.3 2.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.8 EDN10449.1 - 1.1 7.9 8.2 1.1 7.8 5.7 1.1 1 0 0 1 1 1 0 Paf1 CobT PF06213.7 EDN10449.1 - 1.1 8.2 9.0 1.3 8.1 6.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Adeno_terminal PF02459.10 EDN10449.1 - 1.2 7.2 5.6 1.2 7.2 3.9 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein PPP4R2 PF09184.6 EDN10449.1 - 1.3 8.5 10.2 1.4 8.3 7.1 1.1 1 0 0 1 1 1 0 PPP4R2 HSP90 PF00183.13 EDN10449.1 - 1.4 7.2 6.3 1.6 7.0 4.4 1.0 1 0 0 1 1 1 0 Hsp90 protein Nha1_C PF08619.5 EDN10449.1 - 2.5 7.2 11.3 3.1 6.9 7.8 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Radial_spoke PF04712.7 EDN10449.1 - 2.7 6.6 7.4 2.9 6.5 5.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein TFIIF_alpha PF05793.7 EDN10449.1 - 5.3 5.2 10.1 6.3 5.0 7.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Trypan_PARP PF05887.6 EDN10449.1 - 9.9 5.9 16.2 12 5.6 11.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PALP PF00291.20 EDN10450.1 - 5.5e-55 186.7 1.2 9.6e-55 185.9 0.8 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EDN10450.1 - 8.5e-45 150.2 0.0 1.4e-22 79.1 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase ACT PF01842.20 EDN10450.1 - 0.12 11.9 0.1 14 5.3 0.0 2.8 2 0 0 2 2 2 0 ACT domain NLE PF08154.7 EDN10450.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 NLE (NUC135) domain IMS PF00817.15 EDN10450.1 - 0.14 11.9 0.0 3.5 7.3 0.0 2.2 2 0 0 2 2 2 0 impB/mucB/samB family GTP_EFTU PF00009.22 EDN10452.1 - 4e-53 179.6 0.8 5.2e-53 179.2 0.5 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EDN10452.1 - 0.005 16.4 0.1 0.028 13.9 0.1 2.2 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Abhydrolase_6 PF12697.2 EDN10453.1 - 2.8e-10 40.4 1.3 4.2e-10 39.9 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN10453.1 - 1.9e-09 37.4 0.0 3.7e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EDN10453.1 - 0.00014 21.5 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EDN10453.1 - 0.0023 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EDN10453.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF818 PF05677.7 EDN10453.1 - 0.048 12.3 0.0 0.069 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) TLD PF07534.11 EDN10455.1 - 3.5e-19 69.1 0.0 6.6e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 TLD NMT PF01233.14 EDN10456.1 - 8.2e-83 275.8 0.0 1.3e-82 275.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EDN10456.1 - 2.4e-74 248.8 0.0 6.7e-74 247.3 0.0 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EDN10456.1 - 2.4e-07 30.6 0.0 3.4e-06 26.9 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF427 PF04248.7 EDN10456.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Mur_ligase_M PF08245.7 EDN10457.1 - 1.8e-06 28.1 0.4 3.2e-05 24.0 0.3 2.6 1 1 0 1 1 1 1 Mur ligase middle domain Syja_N PF02383.13 EDN10458.1 - 1.1e-91 306.8 0.1 1.5e-91 306.5 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.17 EDN10459.1 - 2e-47 160.5 0.5 2.3e-47 160.3 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN10459.1 - 5.6e-12 46.2 0.1 9.8e-12 45.4 0.1 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EDN10459.1 - 6.5e-11 41.7 0.1 7.7e-11 41.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDN10459.1 - 1e-07 31.5 0.1 1.1e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDN10459.1 - 7e-05 22.0 0.1 8.4e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Shikimate_DH PF01488.15 EDN10459.1 - 0.083 12.9 0.0 0.34 11.0 0.0 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Mitofilin PF09731.4 EDN10460.1 - 5.7e-160 533.7 26.2 9.2e-160 533.0 18.2 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Ribosomal_L20 PF00453.13 EDN10460.1 - 0.047 13.6 1.2 0.13 12.2 0.8 1.8 1 1 0 1 1 1 0 Ribosomal protein L20 DUF4208 PF13907.1 EDN10460.1 - 0.32 11.2 2.4 1.6 8.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) Gp58 PF07902.6 EDN10461.1 - 0.023 12.9 0.1 0.034 12.3 0.1 1.1 1 0 0 1 1 1 0 gp58-like protein DUF3099 PF11298.3 EDN10461.1 - 0.056 13.1 0.5 0.13 11.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) NBP1 PF08537.5 EDN10462.1 - 2.6 7.1 4.8 19 4.3 0.5 2.5 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 DSBA PF01323.15 EDN10463.1 - 6.6e-07 29.0 0.0 7.2e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Methyltransf_16 PF10294.4 EDN10465.1 - 5.9e-47 159.3 0.0 8.2e-47 158.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EDN10465.1 - 3.3e-06 26.7 0.0 4.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN10465.1 - 9.2e-06 25.4 0.0 1.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN10465.1 - 0.00022 21.7 0.0 0.00055 20.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN10465.1 - 0.00042 20.3 0.1 0.00078 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN10465.1 - 0.00072 19.9 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN10465.1 - 0.00092 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EDN10465.1 - 0.035 14.4 0.0 0.092 13.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain B12-binding PF02310.14 EDN10465.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Orn_Arg_deC_N PF02784.11 EDN10466.1 - 2.6e-78 262.6 0.0 3.4e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EDN10466.1 - 3.3e-29 100.9 0.0 5.4e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Rho_N PF07498.7 EDN10466.1 - 0.28 10.9 1.9 6.9 6.5 0.3 2.4 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain cobW PF02492.14 EDN10467.1 - 2e-36 125.0 0.0 4.3e-36 124.0 0.0 1.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EDN10467.1 - 0.068 12.7 0.1 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EDN10467.1 - 0.07 12.8 0.2 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 EDN10467.1 - 0.093 12.4 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.9 EDN10467.1 - 0.098 12.3 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain SET PF00856.23 EDN10468.1 - 2.7e-07 31.0 0.0 4.3e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 SET domain HATPase_c PF02518.21 EDN10469.1 - 2.7e-09 36.7 0.0 5.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EDN10469.1 - 4.8e-09 35.9 0.1 5.6e-08 32.5 0.0 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EDN10469.1 - 2e-06 27.2 0.0 4.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Abhydrolase_6 PF12697.2 EDN10471.1 - 2.2e-27 96.4 3.8 6.3e-27 94.9 2.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN10471.1 - 2.9e-10 40.1 0.0 3.4e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDN10471.1 - 2.3e-06 27.4 0.0 1.4e-05 24.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EDN10471.1 - 0.0039 15.7 0.0 0.0058 15.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family Methyltransf_16 PF10294.4 EDN10472.1 - 2.7e-08 33.4 0.0 2.3e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EDN10472.1 - 0.053 14.1 0.0 0.094 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FAM75 PF14650.1 EDN10472.1 - 4.3 6.6 7.8 0.16 11.2 0.3 1.9 2 0 0 2 2 2 0 FAM75 family Methyltransf_18 PF12847.2 EDN10473.1 - 1.3e-12 48.3 0.0 2.2e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN10473.1 - 7.2e-10 38.6 0.0 9.7e-09 34.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN10473.1 - 1.2e-05 25.0 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN10473.1 - 4.1e-05 23.9 0.0 0.00012 22.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN10473.1 - 0.00026 21.0 0.0 0.00046 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN10473.1 - 0.0012 19.1 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN10473.1 - 0.0019 18.6 1.7 0.0076 16.7 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain MetW PF07021.7 EDN10473.1 - 0.0062 15.9 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Prothymosin PF03247.9 EDN10473.1 - 0.024 14.7 14.7 0.024 14.7 10.2 2.5 3 0 0 3 3 2 0 Prothymosin/parathymosin family Nop14 PF04147.7 EDN10473.1 - 0.4 8.5 10.5 0.65 7.8 7.3 1.3 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 EDN10473.1 - 1.8 7.1 16.8 3.1 6.4 11.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EDN10473.1 - 3.2 5.6 5.5 4.6 5.1 3.8 1.2 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 EDN10473.1 - 6.4 5.6 6.1 13 4.6 4.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DDE_1 PF03184.14 EDN10474.1 - 4.2e-07 29.3 0.0 1.5e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Borrelia_P83 PF05262.6 EDN10474.1 - 7.1 4.7 24.8 9.6 4.3 17.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Asp-B-Hydro_N PF05279.6 EDN10474.1 - 8.7 6.1 17.1 14 5.4 11.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Kv2channel PF03521.9 EDN10475.1 - 0.057 12.8 0.0 0.084 12.3 0.0 1.1 1 0 0 1 1 1 0 Kv2 voltage-gated K+ channel Rotamase_3 PF13616.1 EDN10476.1 - 3.9e-12 46.4 0.3 8.9e-12 45.3 0.1 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EDN10476.1 - 3.5e-11 43.6 0.0 6.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain UAA PF08449.6 EDN10477.1 - 1.1e-28 100.0 2.8 1.4e-28 99.7 2.0 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EDN10477.1 - 3.4e-05 23.8 6.6 4.5e-05 23.4 4.5 1.3 1 1 0 1 1 1 1 EamA-like transporter family EmrE PF13536.1 EDN10477.1 - 0.0002 21.5 6.5 0.0002 21.5 4.5 1.4 1 1 0 1 1 1 1 Multidrug resistance efflux transporter TPT PF03151.11 EDN10477.1 - 0.0013 18.4 7.5 0.002 17.8 5.2 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EDN10477.1 - 0.044 12.8 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-sugar transporter PH PF00169.24 EDN10478.1 - 2e-08 34.3 0.1 1.3e-07 31.7 0.0 2.4 2 0 0 2 2 2 1 PH domain GRAM PF02893.15 EDN10478.1 - 0.00037 19.9 0.1 0.00092 18.6 0.1 1.6 1 0 0 1 1 1 1 GRAM domain bPH_3 PF14470.1 EDN10478.1 - 0.15 12.3 0.1 0.79 10.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial PH domain DUF4286 PF14114.1 EDN10478.1 - 0.37 11.0 1.7 6.2 7.1 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Kri1_C PF12936.2 EDN10479.1 - 7.9e-31 105.8 0.3 7.9e-31 105.8 0.2 4.8 3 1 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 EDN10479.1 - 8.4e-29 99.8 17.4 8.4e-29 99.8 12.1 6.1 4 2 0 5 5 5 1 KRI1-like family AHS2 PF02626.10 EDN10479.1 - 0.017 14.4 0.3 0.032 13.5 0.2 1.4 1 0 0 1 1 1 0 Allophanate hydrolase subunit 2 Mito_carr PF00153.22 EDN10480.1 - 2.9e-67 222.4 5.0 1.1e-24 85.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Stb3 PF10330.4 EDN10482.1 - 1.4e-37 127.2 0.0 2.3e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein PTS_2-RNA PF01885.11 EDN10483.1 - 4.2e-72 241.3 0.0 6.9e-72 240.6 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Utp13 PF08625.6 EDN10483.1 - 0.12 11.9 0.2 1.2 8.7 0.1 2.2 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain Mucin PF01456.12 EDN10483.1 - 6.1 6.6 25.9 18 5.1 17.9 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2361 PF10153.4 EDN10484.1 - 1.5e-36 125.0 8.2 1.5e-36 125.0 5.7 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) Caldesmon PF02029.10 EDN10485.1 - 1.3 7.3 4.7 1.7 6.9 3.3 1.1 1 0 0 1 1 1 0 Caldesmon LRR_1 PF00560.28 EDN10486.1 - 1.9e-06 27.0 10.2 3.1 8.1 0.1 6.3 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 EDN10486.1 - 4.9e-06 26.0 10.3 3.9 7.8 0.0 6.8 7 0 0 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 EDN10486.1 - 6.5e-05 22.4 11.6 1.1 9.7 0.1 6.2 6 0 0 6 6 6 2 Leucine rich repeat LRR_4 PF12799.2 EDN10486.1 - 0.00011 21.6 9.9 1.2 8.7 0.3 5.1 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) Pkinase PF00069.20 EDN10487.1 - 7.6e-60 202.2 0.0 1e-59 201.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN10487.1 - 7.8e-22 77.5 0.0 1.2e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN10487.1 - 6.2e-07 28.6 0.0 1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDN10487.1 - 1.7e-05 24.6 0.6 0.0034 17.1 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 EDN10487.1 - 0.00018 20.8 0.6 0.00049 19.5 0.4 1.7 1 1 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 EDN10487.1 - 0.085 11.6 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RabGAP-TBC PF00566.13 EDN10488.1 - 5.9e-35 120.6 1.9 8.3e-35 120.1 1.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Yippee-Mis18 PF03226.9 EDN10490.1 - 1.9e-24 85.4 1.4 2.2e-24 85.3 1.0 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.4 EDN10490.1 - 0.0023 17.8 1.4 0.0089 16.0 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) DUF4451 PF14616.1 EDN10490.1 - 0.0076 16.0 0.4 0.01 15.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) HNH_5 PF14279.1 EDN10490.1 - 0.0096 15.9 0.6 0.91 9.5 0.0 2.2 1 1 1 2 2 2 1 HNH endonuclease SH2_2 PF14633.1 EDN10490.1 - 0.036 13.1 0.0 0.047 12.7 0.0 1.1 1 0 0 1 1 1 0 SH2 domain Endonuclease_7 PF02945.10 EDN10490.1 - 0.052 13.2 1.4 0.13 11.9 0.7 1.9 1 1 0 1 1 1 0 Recombination endonuclease VII RIG-I_C-RD PF11648.3 EDN10490.1 - 0.066 13.0 2.1 0.13 12.1 1.4 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I Evr1_Alr PF04777.8 EDN10490.1 - 0.076 12.9 1.6 0.66 9.9 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family U79_P34 PF03064.11 EDN10491.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 KH_1 PF00013.24 EDN10492.1 - 4.8e-40 135.0 8.9 4.1e-16 58.3 0.1 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EDN10492.1 - 1.7e-29 100.9 11.3 8.7e-12 44.4 1.0 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EDN10492.1 - 1.5e-10 40.5 6.9 0.0019 17.7 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EDN10492.1 - 4.2e-09 35.9 1.7 0.085 12.5 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EDN10492.1 - 0.00057 19.6 4.2 0.4 10.5 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EDN10492.1 - 0.019 14.4 0.2 3.2 7.2 0.0 3.1 3 0 0 3 3 3 0 dUTPase Epimerase PF01370.16 EDN10493.1 - 1.8e-19 70.1 0.0 2.8e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDN10493.1 - 3.1e-14 52.3 0.0 4.6e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EDN10493.1 - 2.5e-11 43.9 0.2 6.7e-11 42.5 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EDN10493.1 - 1.7e-10 40.2 0.1 9.1e-10 37.8 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EDN10493.1 - 1.1e-06 28.6 0.0 2.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EDN10493.1 - 0.00016 20.7 0.0 0.0024 16.8 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EDN10493.1 - 0.00017 20.6 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EDN10493.1 - 0.00029 20.5 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EDN10493.1 - 0.0029 16.8 0.1 0.011 14.9 0.0 2.0 3 0 0 3 3 3 1 NmrA-like family DAO PF01266.19 EDN10494.1 - 2e-30 105.8 0.0 2.5e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EDN10494.1 - 0.017 14.8 0.0 0.049 13.4 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDN10494.1 - 0.087 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EDN10494.1 - 0.16 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_33 PF10017.4 EDN10495.1 - 1e-06 28.6 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Fungal_trans_2 PF11951.3 EDN10496.1 - 1.7e-09 36.7 1.4 4.6e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF2537 PF10801.3 EDN10498.1 - 0.18 11.9 2.7 0.34 11.0 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2537) Pterin_4a PF01329.14 EDN10499.1 - 1.2e-20 73.0 0.4 1.6e-20 72.6 0.3 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Agglutinin PF07468.6 EDN10499.1 - 0.066 13.1 0.1 0.097 12.6 0.1 1.4 1 0 0 1 1 1 0 Agglutinin Aminotran_3 PF00202.16 EDN10500.1 - 6.9e-37 127.0 0.0 1.4e-36 126.0 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III DSPc PF00782.15 EDN10502.1 - 1.7e-22 79.4 0.0 2.6e-19 69.1 0.0 2.3 1 1 1 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDN10502.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Peptidase_S58 PF03576.9 EDN10503.1 - 1.9e-40 139.0 8.6 5.9e-36 124.2 2.4 2.0 1 1 1 2 2 2 2 Peptidase family S58 Ribosomal_L7Ae PF01248.21 EDN10505.1 - 1.9e-26 91.4 0.4 2.3e-26 91.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 EDN10505.1 - 0.062 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Vac_ImportDeg PF09783.4 EDN10506.1 - 1.6e-26 92.8 0.9 6.2e-26 90.9 0.4 1.9 2 0 0 2 2 2 1 Vacuolar import and degradation protein MR_MLE_C PF13378.1 EDN10507.1 - 1.6e-32 111.7 0.0 3e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EDN10507.1 - 4.5e-12 45.9 0.4 4.3e-10 39.5 0.1 2.7 2 1 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EDN10507.1 - 2.1e-09 37.7 0.0 6.3e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain IU_nuc_hydro PF01156.14 EDN10508.1 - 3.5e-73 246.5 0.0 4.6e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PXA PF02194.10 EDN10509.1 - 2.4e-43 147.8 0.4 3.1e-43 147.4 0.3 1.1 1 0 0 1 1 1 1 PXA domain HTH_Tnp_Tc5 PF03221.11 EDN10510.1 - 1.2e-15 57.0 0.3 2.2e-15 56.1 0.2 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EDN10510.1 - 1.3e-07 30.8 0.2 5.8e-07 28.8 0.0 2.1 3 0 0 3 3 3 1 CENP-B N-terminal DNA-binding domain MarR PF01047.17 EDN10510.1 - 0.015 14.9 0.1 0.069 12.8 0.0 2.1 2 0 0 2 2 2 0 MarR family HTH_Crp_2 PF13545.1 EDN10510.1 - 0.018 14.8 0.0 0.075 12.8 0.0 2.0 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.11 EDN10510.1 - 0.022 14.0 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.1 EDN10510.1 - 0.08 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_23 PF13384.1 EDN10510.1 - 0.088 12.4 0.1 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_4 PF13613.1 EDN10510.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR_2 PF12802.2 EDN10510.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 MarR family RVT_2 PF07727.9 EDN10511.1 - 7.3e-58 195.4 0.0 5e-57 192.6 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN10511.1 - 4e-14 52.7 0.0 1.6e-13 50.7 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN10511.1 - 7.8e-08 31.8 0.0 2.6e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 EDN10511.1 - 1.6 8.8 5.5 3.3 7.8 3.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Cpn60_TCP1 PF00118.19 EDN10512.1 - 5.6e-123 411.1 12.1 7.3e-123 410.7 8.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 EDN10512.1 - 0.041 13.3 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Phage Tail Protein X AAA PF00004.24 EDN10513.1 - 4.9e-41 140.0 0.0 8.2e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN10513.1 - 4.9e-06 26.7 0.0 0.00059 19.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDN10513.1 - 4e-05 23.3 0.1 0.00026 20.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDN10513.1 - 0.00017 21.5 0.0 0.00059 19.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EDN10513.1 - 0.00023 21.1 0.0 0.00093 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EDN10513.1 - 0.0018 17.2 0.0 0.0032 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EDN10513.1 - 0.0042 17.9 0.1 0.013 16.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDN10513.1 - 0.0091 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EDN10513.1 - 0.0096 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EDN10513.1 - 0.019 14.8 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EDN10513.1 - 0.024 14.5 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDN10513.1 - 0.035 14.0 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDN10513.1 - 0.047 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EDN10513.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EDN10513.1 - 0.071 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 EDN10513.1 - 0.073 12.6 0.0 0.62 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EDN10513.1 - 0.076 12.5 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EDN10513.1 - 0.079 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 EDN10513.1 - 0.1 12.9 0.0 0.36 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EDN10513.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 EDN10513.1 - 0.11 12.1 0.2 9.8 5.7 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase FAD_binding_2 PF00890.19 EDN10514.1 - 1.3e-126 422.7 2.8 1.7e-126 422.4 2.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EDN10514.1 - 4.6e-48 162.3 0.7 6.7e-48 161.7 0.5 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EDN10514.1 - 4.1e-07 30.0 0.1 0.0015 18.4 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDN10514.1 - 7.9e-06 25.1 0.0 0.011 14.8 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EDN10514.1 - 3.8e-05 22.7 1.9 0.028 13.3 1.6 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EDN10514.1 - 9.2e-05 21.4 0.1 0.0013 17.6 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EDN10514.1 - 0.0042 16.1 0.2 0.0092 15.0 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EDN10514.1 - 0.79 8.1 4.4 0.6 8.5 0.5 2.5 4 0 0 4 4 4 0 HI0933-like protein DPPIV_N PF00930.16 EDN10515.1 - 1.7e-100 336.0 0.1 2.4e-100 335.5 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EDN10515.1 - 2e-56 190.5 2.1 1.1e-55 188.1 2.3 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDN10515.1 - 3.3e-09 36.6 0.1 6.2e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDN10515.1 - 4.4e-06 26.7 0.1 4.1e-05 23.5 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EDN10515.1 - 0.00013 21.4 4.2 0.00078 18.9 1.8 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 EDN10515.1 - 0.003 17.0 0.1 0.75 9.1 0.1 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.13 EDN10515.1 - 0.019 14.2 0.1 0.1 11.8 0.1 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.8 EDN10515.1 - 0.019 13.2 0.0 4.3 5.5 0.0 2.2 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PI-PLC-X PF00388.14 EDN10517.1 - 1e-62 209.8 0.0 1.6e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EDN10517.1 - 3.7e-38 130.1 0.3 6.2e-38 129.4 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain TGF_beta_GS PF08515.7 EDN10518.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif RTC4 PF14474.1 EDN10519.1 - 1.6e-29 102.3 0.1 2.5e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain Myb_DNA-bind_6 PF13921.1 EDN10519.1 - 1.3e-07 31.5 0.2 3.3e-07 30.3 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN10519.1 - 0.0031 17.5 2.4 0.0075 16.3 1.7 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pkinase PF00069.20 EDN10520.1 - 1e-26 93.6 0.0 2.1e-26 92.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN10520.1 - 1e-09 37.9 0.0 3.8e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDN10520.1 - 0.00015 20.8 0.1 0.013 14.4 0.0 2.7 2 1 0 3 3 3 1 Kinase-like APH PF01636.18 EDN10520.1 - 0.0023 17.7 0.1 0.078 12.7 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family AAA PF00004.24 EDN10523.1 - 7.4e-18 65.0 0.0 1.6e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDN10523.1 - 0.0002 22.1 1.4 0.00096 19.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDN10523.1 - 0.00044 20.2 0.1 0.0036 17.2 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EDN10523.1 - 0.0011 18.6 0.0 0.0028 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN10523.1 - 0.0015 18.6 0.3 0.061 13.4 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 EDN10523.1 - 0.0017 18.6 0.3 0.17 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EDN10523.1 - 0.0099 15.3 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EDN10523.1 - 0.021 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EDN10523.1 - 0.033 13.7 0.0 0.077 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDN10523.1 - 0.085 13.0 0.0 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_3 PF07726.6 EDN10523.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Agouti PF05039.7 EDN10524.1 - 0.19 12.1 1.4 0.27 11.5 0.3 1.7 2 0 0 2 2 2 0 Agouti protein DUF1752 PF08550.5 EDN10526.1 - 0.0036 16.8 3.5 0.0077 15.7 2.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF123 PF01986.11 EDN10526.1 - 0.058 13.4 0.1 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF123 AAA PF00004.24 EDN10528.1 - 2.4e-20 73.0 0.0 8e-20 71.3 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN10528.1 - 0.00059 19.8 0.2 0.0017 18.3 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EDN10528.1 - 0.0011 19.7 0.2 0.021 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain BCS1_N PF08740.6 EDN10528.1 - 0.0034 17.0 0.1 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA_25 PF13481.1 EDN10528.1 - 0.0053 16.1 0.0 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDN10528.1 - 0.019 14.6 0.0 0.081 12.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EDN10528.1 - 0.02 14.7 0.0 0.051 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EDN10528.1 - 0.034 13.2 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 EDN10528.1 - 0.038 14.2 0.0 11 6.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EDN10528.1 - 0.045 13.8 0.0 0.092 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDN10528.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain PPV_E1_C PF00519.12 EDN10528.1 - 0.07 11.7 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RuvB_N PF05496.7 EDN10528.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EDN10528.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain HSDR_N_2 PF13588.1 EDN10529.1 - 0.0043 16.8 0.0 0.46 10.2 0.0 2.4 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) PDZ_assoc PF10600.4 EDN10530.1 - 0.00086 19.5 5.6 3.4 8.0 0.1 4.2 1 1 3 4 4 4 4 PDZ-associated domain of NMDA receptors UBA_e1_thiolCys PF10585.4 EDN10531.1 - 0.03 13.7 2.7 0.097 12.0 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Zn_clus PF00172.13 EDN10532.1 - 5.4e-08 32.6 8.7 5.4e-08 32.6 6.0 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bestrophin PF01062.16 EDN10533.1 - 0.12 11.2 0.4 0.39 9.6 0.1 1.8 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel Exo_endo_phos_2 PF14529.1 EDN10534.1 - 5.8e-12 45.2 0.0 8.4e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase MethyTransf_Reg PF10119.4 EDN10534.1 - 0.085 13.3 0.1 0.97 9.9 0.0 2.3 2 1 0 2 2 2 0 Predicted methyltransferase regulatory domain DUF624 PF04854.9 EDN10535.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF624 DUF4219 PF13961.1 EDN10536.1 - 0.0029 16.9 0.2 0.0057 16.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Myb_DNA-bind_6 PF13921.1 EDN10538.1 - 0.00084 19.4 0.1 0.0018 18.3 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2200 PF09966.4 EDN10539.1 - 0.012 15.4 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) DDE_1 PF03184.14 EDN10540.1 - 3.7e-37 127.5 0.0 7.3e-37 126.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Pox_VP8_L4R PF04498.7 EDN10540.1 - 0.028 13.7 0.0 2.9 7.1 0.0 2.8 2 1 1 3 3 3 0 Poxvirus nucleic acid binding protein VP8/L4R TraG_N PF07916.6 EDN10540.1 - 0.59 8.4 3.7 0.87 7.9 2.6 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF2229 PF09989.4 EDN10540.1 - 1.8 7.9 8.3 20 4.5 5.7 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DDE_1 PF03184.14 EDN10541.1 - 1.7e-25 89.4 0.0 2.6e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN10541.1 - 7.8e-05 22.4 0.0 0.00023 20.9 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease Ofd1_CTDD PF10637.4 EDN10541.1 - 0.067 12.3 0.2 0.093 11.8 0.2 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term DUF3505 PF12013.3 EDN10545.1 - 1.2e-38 131.7 5.9 1.2e-38 131.7 4.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) DUF2225 PF09986.4 EDN10545.1 - 0.085 12.3 0.3 1.2 8.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) LEA_1 PF03760.10 EDN10547.1 - 1.9 8.6 4.8 1.1 9.4 0.4 2.2 2 0 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 CENP-B_dimeris PF09026.5 EDN10548.1 - 2.9 8.1 10.4 7.9 6.7 7.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EDN10548.1 - 3.2 7.2 7.3 5.8 6.4 5.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF4366 PF14283.1 EDN10548.1 - 4.6 6.6 6.9 12 5.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Sugar_tr PF00083.19 EDN10549.1 - 4.2e-13 48.6 1.8 5.4e-13 48.3 1.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN10549.1 - 5.8e-10 38.4 8.8 8.3e-10 37.8 6.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 EDN10549.1 - 0.025 13.0 1.8 0.031 12.7 1.2 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like RNase_H PF00075.19 EDN10550.1 - 1.4e-11 44.8 0.0 2.3e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 RNase H DUF624 PF04854.9 EDN10552.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF624 Peptidase_S8 PF00082.17 EDN10554.1 - 1.4e-55 188.4 1.1 1.9e-55 188.0 0.8 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EDN10554.1 - 1e-29 102.1 1.2 2e-29 101.1 0.9 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain PX PF00787.19 EDN10556.1 - 4.5e-18 65.0 0.3 1e-17 63.9 0.2 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EDN10556.1 - 2.1e-14 53.3 8.6 2.9e-07 29.9 0.4 2.1 2 0 0 2 2 2 2 Vps5 C terminal like DUF1664 PF07889.7 EDN10556.1 - 0.18 11.5 2.4 5.3 6.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BAR PF03114.13 EDN10556.1 - 0.25 10.8 8.2 4.8 6.6 5.7 2.3 1 1 0 1 1 1 0 BAR domain IncA PF04156.9 EDN10556.1 - 0.43 10.1 4.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 IncA protein Prefoldin_2 PF01920.15 EDN10556.1 - 0.46 10.2 5.9 1.2 8.9 0.3 2.5 2 0 0 2 2 2 0 Prefoldin subunit PilJ PF13675.1 EDN10556.1 - 0.66 10.3 3.9 2.4 8.4 0.1 2.9 2 2 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Laminin_II PF06009.7 EDN10556.1 - 0.84 9.3 3.5 0.39 10.4 0.3 2.0 2 1 1 3 3 3 0 Laminin Domain II V_ATPase_I PF01496.14 EDN10556.1 - 2.7 5.7 4.2 7.8 4.2 0.2 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EDN10556.1 - 9.4 5.8 7.7 9.9 5.7 0.2 2.8 3 1 0 3 3 3 0 Septum formation initiator Pyr_redox_2 PF07992.9 EDN10558.1 - 1.7e-17 63.9 0.0 2.3e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN10558.1 - 5.2e-14 52.4 0.0 2.1e-13 50.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDN10558.1 - 2.1e-05 24.6 0.0 6.8e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EDN10558.1 - 0.0014 18.8 0.1 0.0035 17.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Amino_oxidase PF01593.19 EDN10559.1 - 4e-95 319.5 0.0 6e-95 318.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EDN10559.1 - 1.5e-11 44.2 0.0 3.5e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EDN10559.1 - 1.6e-07 31.2 0.0 2.5e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDN10559.1 - 0.00025 20.0 0.1 0.0086 15.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EDN10559.1 - 0.00074 19.6 0.0 0.27 11.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HMG_box PF00505.14 EDN10559.1 - 0.001 19.2 0.2 0.018 15.2 0.2 2.4 1 1 0 1 1 1 1 HMG (high mobility group) box Pyr_redox_2 PF07992.9 EDN10559.1 - 0.0014 18.5 0.0 0.068 13.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDN10559.1 - 0.0035 17.1 0.1 0.13 12.0 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EDN10559.1 - 0.12 10.7 0.1 1.5 7.2 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.19 EDN10559.1 - 2.6 6.7 6.3 2.9 6.6 1.3 2.2 2 0 0 2 2 2 0 FAD binding domain SNARE_assoc PF09335.6 EDN10560.1 - 1.6e-11 44.4 4.9 1.6e-11 44.4 3.4 2.8 2 1 1 3 3 3 1 SNARE associated Golgi protein Ni_hydr_CYTB PF01292.15 EDN10560.1 - 0.005 16.2 3.0 2.9 7.2 0.0 2.3 2 0 0 2 2 2 2 Prokaryotic cytochrome b561 DUF3552 PF12072.3 EDN10560.1 - 0.0076 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) HAMP PF00672.20 EDN10560.1 - 0.084 13.0 5.4 0.16 12.1 0.0 3.2 3 0 0 3 3 3 0 HAMP domain Colicin_V PF02674.11 EDN10560.1 - 1.6 8.5 11.0 0.95 9.3 2.2 2.9 2 1 1 3 3 3 0 Colicin V production protein FA_desaturase PF00487.19 EDN10560.1 - 1.7 8.0 5.7 3.9 6.8 3.5 1.9 2 1 0 2 2 2 0 Fatty acid desaturase 7TMR-DISM_7TM PF07695.6 EDN10560.1 - 4.4 6.9 13.5 0.2 11.2 3.6 2.4 1 1 0 2 2 2 0 7TM diverse intracellular signalling Smr PF01713.16 EDN10561.1 - 4.1e-12 46.1 0.1 1.5e-11 44.3 0.0 2.0 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 EDN10561.1 - 2.6e-09 36.9 8.4 2.6e-09 36.9 5.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.19 EDN10561.1 - 3.1e-08 33.0 1.9 0.0042 16.7 0.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 EDN10561.1 - 0.018 15.1 0.0 0.053 13.6 0.0 1.8 2 0 0 2 2 2 0 HBS1 N-terminus CUE PF02845.11 EDN10561.1 - 0.028 13.8 0.1 0.072 12.5 0.1 1.7 1 0 0 1 1 1 0 CUE domain zf-C3H1 PF10650.4 EDN10561.1 - 1.3 8.5 3.3 12 5.5 0.0 2.6 2 1 0 2 2 2 0 Putative zinc-finger domain zf-CCCH_2 PF14608.1 EDN10561.1 - 2.6 8.1 6.9 0.13 12.3 0.3 2.2 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type DUF846 PF05832.7 EDN10562.1 - 2.4e-42 144.0 9.1 2.8e-42 143.7 6.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Acyl-CoA_dh_1 PF00441.19 EDN10563.1 - 0.00028 21.0 0.3 0.00033 20.7 0.2 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain StbA PF06406.6 EDN10563.1 - 0.076 11.9 0.0 0.082 11.8 0.0 1.0 1 0 0 1 1 1 0 StbA protein ECH PF00378.15 EDN10564.1 - 3.7e-34 117.9 0.0 1.3e-25 89.9 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family zf-CCHC PF00098.18 EDN10565.1 - 3.8e-23 80.2 37.4 3.3e-06 26.7 1.7 6.3 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.1 EDN10565.1 - 1.7e-06 27.5 22.4 0.13 11.9 0.1 4.9 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_6 PF15288.1 EDN10565.1 - 0.00031 20.3 35.1 0.14 11.8 1.4 5.2 4 1 1 5 5 5 4 Zinc knuckle Elf1 PF05129.8 EDN10565.1 - 0.0037 16.9 4.0 0.0037 16.9 2.8 3.4 1 1 2 3 3 3 1 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 EDN10565.1 - 5 6.7 22.8 1.7 8.2 2.6 4.6 4 1 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EDN10565.1 - 7 6.4 22.4 4.1 7.1 2.8 4.6 4 1 0 4 4 4 0 zinc-ribbon domain zf-CCHC_2 PF13696.1 EDN10565.1 - 7.1 6.2 16.8 4.1 6.9 0.1 5.3 5 1 1 6 6 6 0 Zinc knuckle MFS_1 PF07690.11 EDN10566.1 - 2.9e-26 92.0 26.3 2.9e-26 92.0 18.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EDN10566.1 - 0.0014 18.1 1.6 0.0026 17.2 1.1 1.4 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Gln-synt_N PF03951.14 EDN10567.1 - 8.5e-22 76.5 0.0 1.2e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.19 EDN10567.1 - 4.2e-21 75.2 0.0 5.7e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Med1 PF10744.4 EDN10568.1 - 4.1e-42 144.3 0.0 6.2e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Med1 PF10744.4 EDN10569.1 - 3.2e-86 289.5 0.0 4.2e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 WD40 PF00400.27 EDN10570.1 - 2e-60 198.6 26.8 2.8e-12 45.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EDN10570.1 - 0.00034 18.8 7.7 0.38 8.8 0.2 3.9 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EDN10570.1 - 0.0044 15.3 0.0 0.31 9.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain DUF2683 PF10884.3 EDN10570.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) PD40 PF07676.7 EDN10570.1 - 0.13 11.9 0.5 41 3.9 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Sdh5 PF03937.11 EDN10571.1 - 2e-24 85.0 0.6 4.4e-24 83.9 0.4 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Pheromone PF08015.6 EDN10571.1 - 1.4 9.8 3.8 3.5 8.5 0.1 2.6 2 0 0 2 2 2 0 Fungal mating-type pheromone EMP24_GP25L PF01105.19 EDN10572.1 - 1e-42 145.9 0.0 1.2e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pox_Ag35 PF03286.9 EDN10574.1 - 0.0097 15.4 5.1 0.015 14.8 3.5 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.3 EDN10574.1 - 0.046 13.6 11.9 0.071 13.0 8.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Mpp10 PF04006.7 EDN10574.1 - 0.27 9.5 10.9 0.35 9.1 7.6 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.7 EDN10574.1 - 1.3 6.8 11.3 1.6 6.5 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 EDN10574.1 - 1.9 7.1 14.1 2.8 6.5 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 EDN10574.1 - 3.1 7.0 12.6 4.2 6.5 8.8 1.1 1 0 0 1 1 1 0 SDA1 NDUFA12 PF05071.11 EDN10577.1 - 4.6e-13 49.5 0.2 9.9e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.26 EDN10578.1 - 3.6e-10 39.8 0.0 6.8e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain adh_short_C2 PF13561.1 EDN10580.1 - 8.1e-27 94.5 0.1 1.2e-26 93.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDN10580.1 - 2.6e-24 86.0 0.4 3.8e-24 85.4 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN10580.1 - 3.4e-11 43.1 0.3 6.2e-11 42.2 0.2 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EDN10580.1 - 0.046 12.4 0.0 0.064 11.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDN10580.1 - 0.14 11.5 0.1 0.3 10.4 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HAD_2 PF13419.1 EDN10582.1 - 4.8e-14 52.9 0.0 1.8e-12 47.8 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDN10582.1 - 5.1e-10 40.1 0.1 1.4e-07 32.1 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDN10582.1 - 6.7e-10 38.5 0.1 1.2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EDN10582.1 - 1.1e-05 25.6 0.0 1.8e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EDN10582.1 - 0.003 16.9 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase S6PP PF05116.8 EDN10582.1 - 0.011 15.0 0.0 0.03 13.6 0.0 1.6 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 EDN10582.1 - 0.11 12.0 0.0 7.4 6.0 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase VESA1_N PF12785.2 EDN10583.1 - 3.1 6.6 15.9 5 5.9 11.0 1.2 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 ORMDL PF04061.9 EDN10584.1 - 2.5e-58 195.4 4.9 3.2e-58 195.1 3.4 1.0 1 0 0 1 1 1 1 ORMDL family Spo0A_C PF08769.6 EDN10585.1 - 0.15 11.9 0.1 0.62 9.9 0.0 1.9 2 0 0 2 2 2 0 Sporulation initiation factor Spo0A C terminal DUF2236 PF09995.4 EDN10587.1 - 1.4e-38 132.5 0.4 2.1e-38 132.0 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF4217 PF13959.1 EDN10588.1 - 8.3e-23 79.7 0.1 1.4e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EDN10588.1 - 1.7e-20 72.6 0.0 4.1e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN10588.1 - 5.3e-11 42.3 0.1 1.2e-10 41.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase TRP PF06011.7 EDN10589.1 - 4e-104 348.6 24.2 4.7e-104 348.4 16.8 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel gpUL132 PF11359.3 EDN10589.1 - 0.0013 18.1 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 Glycoprotein UL132 CytochromB561_N PF09786.4 EDN10589.1 - 0.0052 15.2 0.7 0.0081 14.6 0.5 1.2 1 0 0 1 1 1 1 Cytochrome B561, N terminal DUF1419 PF07215.6 EDN10589.1 - 0.11 12.3 1.9 0.13 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1419) SIT PF15330.1 EDN10589.1 - 0.15 12.2 3.5 5.9 7.0 0.0 3.9 4 0 0 4 4 4 0 SHP2-interacting transmembrane adaptor protein, SIT IncA PF04156.9 EDN10589.1 - 0.79 9.2 0.0 0.79 9.2 0.0 2.9 4 0 0 4 4 4 0 IncA protein TRP PF06011.7 EDN10590.1 - 7.6e-17 61.0 0.1 9.4e-17 60.7 0.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel gpUL132 PF11359.3 EDN10590.1 - 0.00047 19.5 0.0 0.00059 19.2 0.0 1.1 1 0 0 1 1 1 1 Glycoprotein UL132 DUF4389 PF14333.1 EDN10590.1 - 0.021 14.4 0.2 0.033 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) IncA PF04156.9 EDN10590.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 IncA protein DUF3602 PF12223.3 EDN10591.1 - 3.8e-17 62.4 5.2 5e-16 58.8 0.7 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) Actin PF00022.14 EDN10592.1 - 9.1e-131 435.8 0.0 1e-130 435.7 0.0 1.0 1 0 0 1 1 1 1 Actin Glyco_tran_28_C PF04101.11 EDN10593.1 - 8.5e-20 71.0 0.1 2.4e-19 69.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EDN10593.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 MRP-S28 PF10213.4 EDN10594.1 - 1.1e-08 35.1 0.0 2.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein SNF2_N PF00176.18 EDN10597.1 - 6.6e-58 195.8 0.1 9.4e-58 195.3 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDN10597.1 - 1.2e-12 47.5 0.0 2.8e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EDN10597.1 - 2.1e-10 39.9 3.2 7.2e-10 38.1 2.2 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.19 EDN10597.1 - 3.5e-07 29.7 4.5 0.0022 17.6 0.2 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 EDN10597.1 - 0.0005 19.5 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN10597.1 - 0.019 14.7 0.0 0.17 11.6 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDN10597.1 - 0.091 12.9 0.1 0.9 9.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain SpoU_methylase PF00588.14 EDN10598.1 - 1.5e-06 28.1 0.1 3.4e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 SpoU rRNA Methylase family SNF2_N PF00176.18 EDN10599.1 - 2.2e-77 259.8 0.1 3.9e-77 258.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HAND PF09110.6 EDN10599.1 - 7.6e-36 122.9 1.8 7.6e-36 122.9 1.3 3.8 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 EDN10599.1 - 2.9e-14 52.6 0.0 1.9e-13 50.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SLIDE PF09111.5 EDN10599.1 - 6.2e-10 38.8 2.5 6.2e-10 38.8 1.7 2.2 2 0 0 2 2 2 1 SLIDE DEAD PF00270.24 EDN10599.1 - 7.1e-06 25.6 0.0 1.9e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN10599.1 - 2.2e-05 24.3 0.1 0.00018 21.4 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 EDN10599.1 - 0.027 13.8 0.1 0.069 12.5 0.0 1.6 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 EDN10599.1 - 0.027 14.3 0.1 0.24 11.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF4588 PF15251.1 EDN10600.1 - 2e-05 24.6 3.0 0.00013 22.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4588) gpW PF02831.10 EDN10600.1 - 0.038 13.5 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 gpW Adap_comp_sub PF00928.16 EDN10601.1 - 5e-52 176.6 0.0 8.6e-52 175.8 0.0 1.4 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EDN10601.1 - 1.6e-05 24.6 0.0 2.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldedh PF00171.17 EDN10602.1 - 2.4e-72 243.7 0.0 4.9e-72 242.7 0.0 1.4 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EDN10602.1 - 0.011 14.4 0.1 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Porin_OmpG PF09381.5 EDN10602.1 - 0.046 12.8 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein G (OmpG) Rif1_N PF12231.3 EDN10603.1 - 1.5e-68 231.4 8.6 5.6e-64 216.4 0.4 2.9 2 1 1 3 3 3 2 Rap1-interacting factor 1 N terminal Polysacc_synt_4 PF04669.8 EDN10604.1 - 2.7e-23 82.3 1.4 1.4e-22 80.0 1.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis DUF2491 PF10679.4 EDN10604.1 - 0.039 12.9 1.0 0.046 12.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Sugar_tr PF00083.19 EDN10605.1 - 5.4e-103 344.9 13.9 4e-65 220.1 2.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDN10605.1 - 1.4e-20 73.3 33.9 9.2e-12 44.3 6.7 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EDN10605.1 - 0.0081 14.6 21.4 0.013 13.9 1.2 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein DUF2530 PF10745.4 EDN10605.1 - 0.19 11.7 3.7 0.14 12.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF21 PF01595.15 EDN10605.1 - 9.7 5.4 7.9 18 4.5 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF21 ABC_tran PF00005.22 EDN10606.1 - 7.4e-29 100.7 0.0 1.2e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EDN10606.1 - 1.6e-05 24.4 3.4 0.16 11.3 0.2 3.0 1 1 1 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EDN10606.1 - 1.6e-05 24.2 0.0 0.021 14.0 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDN10606.1 - 0.00028 20.3 0.0 0.00059 19.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EDN10606.1 - 0.00057 18.5 0.0 0.029 12.9 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_17 PF13207.1 EDN10606.1 - 0.00082 20.1 0.0 0.0018 19.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EDN10606.1 - 0.0023 17.4 0.1 0.0058 16.1 0.1 1.6 1 0 0 1 1 1 1 AAA-like domain AAA_25 PF13481.1 EDN10606.1 - 0.0094 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN10606.1 - 0.0097 15.9 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN10606.1 - 0.01 15.9 0.1 0.083 13.0 0.1 2.2 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EDN10606.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EDN10606.1 - 0.023 14.3 0.1 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EDN10606.1 - 0.033 14.5 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EDN10606.1 - 0.039 13.9 0.4 0.1 12.5 0.2 1.8 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EDN10606.1 - 0.04 12.3 0.2 0.067 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDN10606.1 - 0.043 13.7 0.1 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EDN10606.1 - 0.093 12.6 0.2 0.17 11.8 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF3987 PF13148.1 EDN10606.1 - 0.098 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Zeta_toxin PF06414.7 EDN10606.1 - 0.14 11.1 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 EDN10607.1 - 1.4e-30 106.3 0.0 2.3e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EDN10607.1 - 1.2e-15 57.6 1.6 1.9e-15 57.0 1.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EDN10607.1 - 1.5e-06 27.6 0.1 0.002 17.4 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EDN10607.1 - 1e-05 25.6 0.2 0.00041 20.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN10607.1 - 4.3e-05 24.3 0.2 8.2e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EDN10607.1 - 0.00012 22.1 0.0 0.014 15.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN10607.1 - 0.00042 20.3 0.6 0.0014 18.6 0.4 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EDN10607.1 - 0.001 18.2 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 EDN10607.1 - 0.0018 16.9 0.2 0.02 13.4 0.1 2.3 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.1 EDN10607.1 - 0.003 17.0 0.2 0.0056 16.1 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EDN10607.1 - 0.0066 15.9 0.2 0.18 11.1 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 EDN10607.1 - 0.0072 16.6 0.5 0.02 15.2 0.2 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EDN10607.1 - 0.011 15.1 0.2 0.086 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EDN10607.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein SbcCD_C PF13558.1 EDN10607.1 - 0.015 15.1 0.0 0.042 13.7 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EDN10607.1 - 0.018 14.8 0.1 0.072 12.8 0.1 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 EDN10607.1 - 0.019 14.9 0.5 0.046 13.6 0.3 1.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EDN10607.1 - 0.02 14.0 0.1 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EDN10607.1 - 0.022 14.9 0.3 0.23 11.6 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDN10607.1 - 0.024 14.3 0.1 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EDN10607.1 - 0.025 14.8 0.1 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EDN10607.1 - 0.03 13.9 0.2 0.75 9.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 EDN10607.1 - 0.047 12.5 0.1 0.1 11.4 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.1 EDN10607.1 - 0.06 13.2 0.0 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EDN10607.1 - 0.063 13.1 0.2 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDN10607.1 - 0.083 13.0 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 RNA helicase PRK PF00485.13 EDN10607.1 - 0.14 11.6 0.3 0.23 10.9 0.2 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PgaD PF13994.1 EDN10608.1 - 0.74 9.2 5.5 1.9 7.9 1.1 2.4 2 0 0 2 2 2 0 PgaD-like protein FA_hydroxylase PF04116.8 EDN10610.1 - 9.3e-15 55.0 18.2 9.3e-15 55.0 12.6 2.4 2 2 0 2 2 2 1 Fatty acid hydroxylase superfamily Cep57_MT_bd PF06657.8 EDN10611.1 - 4e-24 84.3 1.4 4e-24 84.3 1.0 3.0 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EDN10611.1 - 1.9e-20 72.5 5.6 1.9e-20 72.5 3.9 3.8 3 0 0 3 3 3 1 Centrosome localisation domain of PPC89 HALZ PF02183.13 EDN10611.1 - 0.0052 16.4 1.0 0.0052 16.4 0.7 3.1 2 1 0 3 3 3 1 Homeobox associated leucine zipper DUF2205 PF10224.4 EDN10611.1 - 2.6 7.6 11.9 0.29 10.7 2.1 3.4 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) bZIP_1 PF00170.16 EDN10611.1 - 7.8 6.5 19.0 0.41 10.6 2.1 4.3 4 0 0 4 4 4 0 bZIP transcription factor MAT1 PF06391.8 EDN10612.1 - 6e-36 123.9 15.6 7.8e-36 123.5 10.8 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EDN10612.1 - 0.00017 21.1 4.5 0.00068 19.2 3.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDN10612.1 - 0.0014 18.2 5.6 0.0028 17.2 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDN10612.1 - 0.0035 17.3 5.7 0.0082 16.1 4.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDN10612.1 - 0.015 15.0 8.1 0.2 11.4 6.0 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 EDN10612.1 - 0.023 14.5 6.0 0.052 13.3 4.2 1.6 1 1 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 EDN10612.1 - 0.22 11.1 7.3 0.64 9.6 1.6 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF572 PF04502.8 EDN10612.1 - 0.9 8.6 11.1 1.2 8.2 7.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Prefoldin_3 PF13758.1 EDN10613.1 - 6.8e-38 128.4 2.3 1.6e-37 127.2 1.6 1.7 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 EDN10613.1 - 1.6e-22 80.2 12.5 8.5e-22 77.9 0.1 4.3 3 1 0 3 3 3 2 Domain of unknown function (DUF3835) Pkinase PF00069.20 EDN10614.1 - 3.1e-43 147.8 0.0 1.5e-42 145.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN10614.1 - 2.6e-26 92.2 0.0 4e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDN10614.1 - 0.0023 17.6 0.2 0.036 13.8 0.0 2.9 3 1 1 4 4 4 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EDN10614.1 - 0.0044 16.0 0.0 0.012 14.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EDN10614.1 - 0.35 9.6 0.0 0.77 8.4 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase NGP1NT PF08153.7 EDN10615.1 - 7.6e-49 164.9 0.1 1.3e-48 164.2 0.1 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EDN10615.1 - 6.4e-19 68.0 0.0 1.6e-14 53.8 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EDN10615.1 - 1.9e-05 23.9 0.0 0.00024 20.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EDN10615.1 - 0.00052 19.8 0.1 0.34 10.7 0.0 3.6 2 1 1 3 3 3 1 Dynamin family Arf PF00025.16 EDN10615.1 - 0.00072 18.8 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 EDN10615.1 - 0.0035 16.5 0.0 0.0077 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EDN10615.1 - 0.0053 16.2 0.0 1.1 8.6 0.0 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain CENP-F_leu_zip PF10473.4 EDN10616.1 - 0.028 14.3 0.8 0.028 14.3 0.5 1.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MRP-S26 PF14943.1 EDN10616.1 - 0.49 9.9 9.1 1.4 8.4 0.2 2.3 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Lactamase_B PF00753.22 EDN10617.1 - 0.0027 17.3 0.1 0.0042 16.7 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily But2 PF09792.4 EDN10618.1 - 1.7e-49 167.2 0.0 2.2e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain PAP2 PF01569.16 EDN10619.1 - 0.00036 20.2 0.1 0.00036 20.2 0.0 1.7 2 0 0 2 2 2 1 PAP2 superfamily DUF872 PF05915.7 EDN10620.1 - 0.039 13.8 0.2 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF2763 PF10961.3 EDN10620.1 - 0.043 14.1 0.1 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) DUF4018 PF13210.1 EDN10620.1 - 0.067 12.5 5.7 0.1 11.9 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) MARVEL PF01284.18 EDN10620.1 - 0.068 12.9 9.4 0.1 12.3 6.5 1.3 1 0 0 1 1 1 0 Membrane-associating domain SCAMP PF04144.8 EDN10620.1 - 2.3 8.0 7.9 0.58 10.0 3.1 1.7 2 0 0 2 2 2 0 SCAMP family AA_permease_2 PF13520.1 EDN10621.1 - 1.5e-88 297.1 24.3 1.5e-88 297.1 16.9 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN10621.1 - 7.1e-15 54.3 27.3 1.1e-14 53.6 18.3 1.6 1 1 1 2 2 2 1 Amino acid permease TPT PF03151.11 EDN10621.1 - 0.0021 17.7 0.1 0.0021 17.7 0.1 2.9 3 1 0 3 3 3 1 Triose-phosphate Transporter family PsbN PF02468.10 EDN10621.1 - 0.71 9.5 4.6 0.5 10.0 0.7 2.7 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) Peptidase_M1 PF01433.15 EDN10622.1 - 5.6e-141 470.1 0.1 7.8e-141 469.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EDN10622.1 - 3.9e-93 312.2 2.5 4.7e-93 311.9 0.2 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EDN10622.1 - 3.2e-19 69.2 0.5 6e-19 68.3 0.3 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Lipocalin_6 PF13944.1 EDN10622.1 - 0.23 11.6 2.5 1.3 9.1 1.4 2.2 2 0 0 2 2 2 0 Lipocalin-like domain Helicase_C PF00271.26 EDN10623.1 - 0.00094 19.0 0.2 0.0015 18.3 0.2 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN10624.1 - 8.3e-41 139.2 0.0 1.2e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDN10624.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TPR_14 PF13428.1 EDN10625.1 - 0.013 16.0 1.3 7.4 7.5 0.0 4.8 4 2 2 6 6 6 0 Tetratricopeptide repeat Suf PF05843.9 EDN10625.1 - 0.025 14.2 10.1 0.031 14.0 0.1 3.0 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) HAT PF02184.11 EDN10625.1 - 2.8 7.7 20.7 10 5.9 0.0 6.3 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat MOSC_N PF03476.11 EDN10627.1 - 9.4e-21 73.7 0.0 1.7e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.14 EDN10627.1 - 5.9e-14 51.5 0.0 8.9e-14 51.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF3543 PF12063.3 EDN10628.1 - 1.2e-102 342.1 0.0 1.8e-102 341.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EDN10628.1 - 7.6e-37 126.8 0.0 2.8e-36 124.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN10628.1 - 1e-22 80.4 0.0 4.7e-22 78.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase CTP_transf_1 PF01148.15 EDN10629.1 - 2e-08 34.2 10.7 3e-05 23.7 2.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase family HTH_psq PF05225.11 EDN10630.1 - 0.021 14.3 3.8 0.072 12.6 2.7 1.9 1 1 0 1 1 1 0 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN10630.1 - 0.037 13.8 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain Phage_mat-A PF03863.8 EDN10631.1 - 0.19 10.7 4.5 0.19 10.7 3.1 1.1 1 0 0 1 1 1 0 Phage maturation protein TraG_N PF07916.6 EDN10631.1 - 0.23 9.8 5.4 0.23 9.8 3.7 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DBINO PF13892.1 EDN10631.1 - 1.2 9.1 24.8 1.4 8.9 17.2 1.0 1 0 0 1 1 1 0 DNA-binding domain CAF-1_p150 PF11600.3 EDN10631.1 - 1.9 7.8 25.6 2.4 7.5 17.7 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2229 PF09989.4 EDN10631.1 - 2.2 7.7 9.5 2.7 7.4 6.6 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DivIVA PF05103.8 EDN10631.1 - 2.5 8.1 21.1 3.2 7.7 14.6 1.1 1 0 0 1 1 1 0 DivIVA protein Hom_end_hint PF05203.11 EDN10631.1 - 3 7.5 11.5 3.4 7.3 8.0 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Borrelia_P83 PF05262.6 EDN10631.1 - 3.1 5.9 22.7 3.5 5.7 15.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Fes1 PF08609.5 EDN10631.1 - 8.6 6.9 7.7 5.7 7.4 3.8 1.8 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 ATP_bind_4 PF01902.12 EDN10632.1 - 1.5e-17 63.7 0.1 1.6e-05 24.3 0.0 4.2 3 1 0 4 4 4 4 ATP-binding region Ribonuc_L-PSP PF01042.16 EDN10632.1 - 1e-08 34.9 0.0 1.3e-06 28.1 0.0 2.9 2 0 0 2 2 2 1 Endoribonuclease L-PSP CDK2AP PF09806.4 EDN10632.1 - 0.0016 18.6 0.4 0.0028 17.9 0.3 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein FAD-SLDH PF12318.3 EDN10632.1 - 0.17 11.5 4.2 0.34 10.5 2.9 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Ribosomal_60s PF00428.14 EDN10632.1 - 1.6 9.1 24.1 67 3.9 15.4 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pkinase PF00069.20 EDN10633.1 - 4.5e-17 62.0 0.0 5.3e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN10633.1 - 1.6e-06 27.3 0.0 2.8e-06 26.6 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase PAT1 PF09770.4 EDN10634.1 - 2.4 6.3 32.5 2.8 6.0 22.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PITH PF06201.8 EDN10635.1 - 1.3e-35 122.4 0.0 4.6e-35 120.6 0.0 1.9 1 1 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EDN10635.1 - 4.4e-29 100.2 0.0 8.9e-29 99.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EDN10635.1 - 9.3e-07 28.8 0.1 2.5e-05 24.2 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EDN10635.1 - 2.4e-05 24.4 0.0 9.1e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EDN10635.1 - 4.5e-05 23.3 0.0 8.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EDN10635.1 - 0.00031 20.4 0.0 0.029 14.0 0.0 2.2 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EDN10635.1 - 0.00052 19.5 0.0 0.2 11.1 0.0 2.2 1 1 1 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 EDN10635.1 - 0.00057 19.4 0.0 0.00091 18.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 EDN10635.1 - 0.032 14.0 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain HyaE PF07449.6 EDN10635.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE zf-CSL PF05207.8 EDN10636.1 - 6.1e-16 57.6 1.1 7.6e-16 57.3 0.1 1.7 2 0 0 2 2 2 1 CSL zinc finger DnaJ PF00226.26 EDN10636.1 - 0.00037 20.1 0.0 0.00071 19.2 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain peroxidase PF00141.18 EDN10637.1 - 2.7e-26 92.4 0.0 3.9e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Dzip-like_N PF13815.1 EDN10638.1 - 0.017 14.8 8.1 0.087 12.6 5.6 1.9 1 1 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF106 PF01956.11 EDN10638.1 - 0.034 13.6 2.0 0.039 13.4 1.4 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF2890 PF11081.3 EDN10638.1 - 0.39 10.7 7.0 0.53 10.3 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Mito_fiss_reg PF05308.6 EDN10638.1 - 3.9 6.7 12.7 5 6.4 3.9 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Zn_clus PF00172.13 EDN10640.1 - 9.3e-05 22.2 6.6 0.0002 21.1 4.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipoprotein_7 PF01540.11 EDN10640.1 - 0.023 13.7 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein FTR PF01913.13 EDN10640.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase WD40 PF00400.27 EDN10641.1 - 1.9e-24 84.5 8.6 5.3e-06 26.1 0.1 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Aconitase PF00330.15 EDN10643.1 - 8.4e-158 525.6 0.1 1e-157 525.3 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EDN10643.1 - 1.4e-41 141.6 0.0 2.8e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Glyco_transf_5 PF08323.6 EDN10644.1 - 5.1e-12 45.7 0.2 1.2e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Arylesterase PF01731.15 EDN10644.1 - 3.5e-08 33.3 0.2 9.1e-08 31.9 0.2 1.8 1 0 0 1 1 1 1 Arylesterase Alpha-amylase PF00128.19 EDN10644.1 - 2.8e-06 26.9 0.4 0.00088 18.7 0.0 3.5 2 1 1 3 3 3 1 Alpha amylase, catalytic domain Glyco_trans_1_4 PF13692.1 EDN10644.1 - 1.6e-05 25.1 0.0 3.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EDN10644.1 - 2.2e-05 23.9 0.0 4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 SGL PF08450.7 EDN10644.1 - 0.00013 21.4 0.1 0.00027 20.4 0.1 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 EDN10644.1 - 0.052 12.6 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Big_5 PF13205.1 EDN10644.1 - 0.11 13.1 0.0 0.11 13.1 0.0 2.7 3 0 0 3 3 3 0 Bacterial Ig-like domain MTHFR PF02219.12 EDN10646.1 - 7.1e-103 343.6 0.0 1e-101 339.8 0.0 2.1 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF2418 PF10332.4 EDN10647.1 - 3.2e-36 123.5 0.7 6.4e-36 122.6 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DUF3593 PF12159.3 EDN10647.1 - 0.049 13.4 0.3 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) ATP-synt_F PF01990.12 EDN10648.1 - 5.7e-06 26.6 0.0 6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit NOGCT PF08155.6 EDN10650.1 - 0.00016 21.2 0.8 0.00041 19.9 0.6 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain DUF506 PF04720.7 EDN10650.1 - 1.8 8.1 8.1 0.31 10.6 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF506) Acetyltransf_1 PF00583.19 EDN10652.1 - 1.3e-09 37.9 0.0 2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN10652.1 - 1.4e-07 31.5 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDN10652.1 - 0.0025 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EDN10652.1 - 0.0083 16.2 0.0 0.031 14.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDN10652.1 - 0.029 14.2 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EDN10652.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Asp_protease PF09668.5 EDN10653.1 - 2.6e-59 198.1 0.4 4.1e-59 197.5 0.3 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EDN10653.1 - 6.9e-11 42.4 0.0 1.9e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 EDN10653.1 - 2.9e-10 39.3 0.2 1e-09 37.6 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin family UBA PF00627.26 EDN10653.1 - 4.2e-09 35.9 0.0 9e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain gag-asp_proteas PF13975.1 EDN10653.1 - 3.4e-06 26.7 0.0 8.1e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EDN10653.1 - 5.4e-05 23.1 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease UN_NPL4 PF11543.3 EDN10653.1 - 0.00014 22.0 0.0 0.00042 20.5 0.0 1.8 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Rad60-SLD PF11976.3 EDN10653.1 - 0.00039 20.0 0.1 0.00085 18.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.15 EDN10653.1 - 0.0059 16.5 0.0 0.029 14.2 0.0 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease DUF2407 PF10302.4 EDN10653.1 - 0.0067 16.5 0.2 0.015 15.5 0.1 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UBA_4 PF14555.1 EDN10653.1 - 0.0073 15.8 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Cu-oxidase_3 PF07732.10 EDN10655.1 - 9e-42 141.5 0.4 5.5e-40 135.7 0.1 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EDN10655.1 - 1.1e-18 67.0 0.4 2.2e-11 43.3 0.0 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EDN10655.1 - 8.7e-16 58.2 0.0 3.8e-15 56.1 0.0 2.1 1 1 0 1 1 1 1 Multicopper oxidase Antitoxin-MazE PF04014.13 EDN10655.1 - 0.15 11.8 0.1 0.42 10.3 0.1 1.7 1 0 0 1 1 1 0 Antidote-toxin recognition MazE Methyltransf_23 PF13489.1 EDN10656.1 - 4.7e-05 23.1 0.0 6.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN10656.1 - 0.00027 21.3 0.0 0.00057 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN10656.1 - 0.0022 18.4 0.0 0.0039 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN10656.1 - 0.0043 17.6 0.0 0.0081 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Git3 PF11710.3 EDN10657.1 - 5.6e-25 88.0 11.9 9.2e-25 87.3 8.3 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EDN10657.1 - 3.8e-08 32.9 0.1 3.8e-08 32.9 0.1 2.9 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EDN10657.1 - 4.7e-08 32.4 7.2 6.5e-08 32.0 5.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EDN10657.1 - 0.0011 17.9 10.0 0.0019 17.1 6.9 1.5 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor PV-1 PF06637.6 EDN10657.1 - 0.18 10.3 0.0 0.33 9.4 0.0 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF1035 PF06281.7 EDN10657.1 - 0.45 10.3 4.7 1.3 8.8 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) Methyltransf_23 PF13489.1 EDN10658.1 - 0.00014 21.5 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EDN10659.1 - 3.2e-45 154.4 0.0 8.7e-45 153.0 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EDN10659.1 - 4.4e-06 27.0 0.0 2.6e-05 24.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN10659.1 - 0.15 12.4 0.0 5.2 7.4 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Proteasome PF00227.21 EDN10660.1 - 7.6e-56 188.4 0.1 9.6e-56 188.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDN10660.1 - 9.4e-14 50.4 0.0 2.2e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Spc97_Spc98 PF04130.8 EDN10661.1 - 9.4e-132 440.0 0.4 1.3e-131 439.6 0.3 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Thiolase_N PF00108.18 EDN10662.1 - 4.5e-43 147.1 0.0 1.6e-34 119.1 0.1 2.0 1 1 1 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDN10662.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Thiolase, C-terminal domain AMP-binding PF00501.23 EDN10663.1 - 6.7e-57 192.7 0.0 8.6e-57 192.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN10663.1 - 0.00012 22.9 0.0 0.00029 21.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain KH_3 PF13014.1 EDN10664.1 - 0.016 14.8 0.5 0.067 12.8 0.0 2.3 3 0 0 3 3 3 0 KH domain KH_1 PF00013.24 EDN10664.1 - 0.062 12.9 0.0 0.062 12.9 0.0 2.8 3 0 0 3 3 3 0 KH domain Agglutinin PF07468.6 EDN10665.1 - 0.073 13.0 0.0 0.26 11.2 0.0 1.7 1 1 1 2 2 2 0 Agglutinin adh_short PF00106.20 EDN10666.1 - 3.1e-19 69.5 0.0 4.3e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN10666.1 - 2.2e-09 37.4 0.0 3.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDN10666.1 - 0.00022 20.9 0.0 0.00073 19.2 0.0 1.8 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EDN10666.1 - 0.026 14.5 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EDN10666.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Erg28 PF03694.8 EDN10667.1 - 2.5e-32 111.1 0.5 2.8e-32 111.0 0.4 1.0 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.17 EDN10668.1 - 9.6e-68 227.8 0.0 1.3e-66 224.1 0.0 2.2 2 1 1 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EDN10668.1 - 1.8e-42 144.6 0.2 4.4e-42 143.4 0.1 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 EDN10668.1 - 0.02 15.4 0.0 0.14 12.7 0.0 2.2 2 0 0 2 2 2 0 HIT domain NAD_binding_2 PF03446.10 EDN10669.1 - 5.2e-27 94.6 0.0 1.3e-26 93.4 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EDN10669.1 - 6.8e-09 36.0 0.0 1.6e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EDN10669.1 - 4.2e-08 33.3 0.0 8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EDN10669.1 - 0.082 12.9 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 EDN10669.1 - 0.15 11.1 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain BAR_2 PF10455.4 EDN10671.1 - 3e-60 203.5 0.0 4.3e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EDN10671.1 - 6.7e-20 71.5 1.0 1.5e-18 67.2 0.7 2.0 1 1 0 1 1 1 1 BAR domain zf-C4H2 PF10146.4 EDN10671.1 - 1.2 9.1 4.0 1.1 9.2 0.3 2.2 1 1 0 2 2 2 0 Zinc finger-containing protein DUF1081 PF06448.6 EDN10672.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) Arv1 PF04161.8 EDN10673.1 - 4.9e-07 29.8 7.0 6.1e-07 29.5 4.9 1.1 1 0 0 1 1 1 1 Arv1-like family DUF619 PF04768.8 EDN10674.1 - 4.4e-48 162.9 0.0 1e-47 161.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Nucleoporin_C PF03177.9 EDN10676.1 - 8.9e-132 440.5 2.7 1.1e-131 440.2 1.9 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EDN10676.1 - 9.6e-90 301.3 0.4 1.3e-89 300.8 0.3 1.2 1 0 0 1 1 1 1 Nup133 N terminal like YqeY PF09424.5 EDN10677.1 - 8.2e-20 71.1 1.0 9.9e-20 70.8 0.7 1.1 1 0 0 1 1 1 1 Yqey-like protein TFCD_C PF12612.3 EDN10677.1 - 0.022 14.1 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal Sulfatase_C PF14707.1 EDN10677.1 - 0.1 12.8 0.1 0.32 11.2 0.0 1.8 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase Rot1 PF10681.4 EDN10678.1 - 1.5e-88 295.7 0.3 1.9e-88 295.3 0.2 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal 5-FTHF_cyc-lig PF01812.15 EDN10679.1 - 3.1e-34 118.3 0.0 7.9e-34 117.0 0.0 1.6 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Xpo1 PF08389.7 EDN10680.1 - 3.3e-29 101.7 0.2 2.7e-28 98.7 0.0 2.7 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EDN10680.1 - 3.3e-06 26.9 0.3 9.4e-05 22.2 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EDN10680.1 - 0.0014 18.8 0.0 0.041 14.1 0.0 3.1 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 EDN10680.1 - 0.0045 17.4 1.1 0.27 11.7 0.0 4.4 4 1 1 5 5 5 1 HEAT-like repeat HEAT PF02985.17 EDN10680.1 - 0.0094 15.9 0.0 6.6 7.0 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat HVSL PF09749.4 EDN10681.1 - 0.027 13.5 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein Fungal_trans PF04082.13 EDN10682.1 - 1e-19 70.4 0.5 1.4e-12 47.0 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EDN10682.1 - 0.0025 18.0 4.7 0.0026 18.0 0.9 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN10682.1 - 0.012 15.9 0.9 0.012 15.9 0.6 2.5 3 0 0 3 3 3 0 C2H2-type zinc finger EF-hand_7 PF13499.1 EDN10683.1 - 2.5e-14 53.1 0.1 6.9e-10 38.9 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EDN10683.1 - 8.5e-12 43.9 0.1 0.00082 19.0 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.27 EDN10683.1 - 4.4e-10 38.1 0.1 0.015 14.6 0.0 3.7 3 1 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EDN10683.1 - 2.5e-08 33.7 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EDN10683.1 - 1.9e-06 27.3 0.5 0.00094 18.7 0.1 3.4 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 EDN10683.1 - 0.062 12.6 2.5 2.4 7.6 0.7 3.3 3 0 0 3 3 3 0 EF hand Nop14 PF04147.7 EDN10684.1 - 0.0015 16.5 7.5 0.0015 16.5 5.2 1.4 2 0 0 2 2 2 1 Nop14-like family Nucleoplasmin PF03066.10 EDN10684.1 - 0.17 11.4 8.0 0.18 11.3 3.8 2.0 2 0 0 2 2 2 0 Nucleoplasmin CDC45 PF02724.9 EDN10684.1 - 0.28 9.1 7.9 0.47 8.4 5.5 1.3 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.7 EDN10684.1 - 0.48 8.4 6.3 0.65 8.0 4.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus TEX19 PF15553.1 EDN10684.1 - 0.62 9.9 4.4 1.3 8.8 3.1 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 Spt5_N PF11942.3 EDN10684.1 - 0.88 10.2 15.9 0.046 14.3 6.5 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Daxx PF03344.10 EDN10684.1 - 1.5 7.2 13.4 2.4 6.5 9.3 1.2 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 EDN10684.1 - 1.5 7.4 11.5 2.9 6.5 8.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pox_RNA_Pol_19 PF05320.7 EDN10684.1 - 3.8 7.2 7.0 7.5 6.2 4.9 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Peptidase_M3 PF01432.15 EDN10685.1 - 7e-35 120.9 0.3 1.6e-34 119.7 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M3 Xan_ur_permease PF00860.15 EDN10686.1 - 9.6e-51 172.4 11.7 1.8e-49 168.2 8.1 2.0 1 1 0 1 1 1 1 Permease family Metallothio_11 PF02066.10 EDN10686.1 - 2.1 8.2 11.7 6.4 6.7 8.1 1.8 1 0 0 1 1 1 0 Metallothionein family 11 p450 PF00067.17 EDN10687.1 - 1.1e-16 60.4 0.0 1.2e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EDN10688.1 - 4.4e-35 121.1 0.1 5.5e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNase_H PF00075.19 EDN10689.1 - 1.2e-07 32.1 0.0 1.9e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 EDN10690.1 - 1.1e-11 44.5 0.0 1.2e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EDN10691.1 - 4.6e-27 94.7 0.2 1.2e-26 93.3 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) APH PF01636.18 EDN10692.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family DDE_1 PF03184.14 EDN10693.1 - 2.5e-50 170.6 0.0 4.2e-50 169.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN10693.1 - 0.0059 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-CCHC_4 PF14392.1 EDN10693.1 - 0.13 11.9 0.1 0.31 10.7 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle AAA PF00004.24 EDN10697.1 - 5.1e-09 36.4 0.0 1.4e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EDN10698.1 - 0.22 11.4 0.2 6.9 6.6 0.0 2.3 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein RTC4 PF14474.1 EDN10699.1 - 1.7e-29 102.2 0.1 1.9e-29 102.1 0.1 1.0 1 0 0 1 1 1 1 RTC4-like domain DNA_mis_repair PF01119.14 EDN10700.1 - 0.071 12.5 0.0 3 7.3 0.0 2.0 2 0 0 2 2 2 0 DNA mismatch repair protein, C-terminal domain Rad51 PF08423.6 EDN10702.1 - 0.00033 19.6 0.0 0.32 9.8 0.0 2.8 2 1 0 2 2 2 2 Rad51 AAA PF00004.24 EDN10702.1 - 0.01 16.0 0.1 0.066 13.4 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EDN10702.1 - 0.015 14.7 0.2 1.9 7.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EDN10702.1 - 0.016 14.2 1.2 0.12 11.4 0.1 2.5 2 1 1 3 3 3 0 KaiC DnaB_C PF03796.10 EDN10702.1 - 0.024 13.4 0.0 1.1 8.0 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ABC_tran PF00005.22 EDN10702.1 - 0.059 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EDN10702.1 - 0.077 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDN10702.1 - 0.095 12.8 0.0 0.28 11.3 0.0 1.8 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.1 EDN10702.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain MOSC PF03473.12 EDN10703.1 - 1.3e-12 47.3 0.3 7.1e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 MOSC domain MOSC_N PF03476.11 EDN10703.1 - 3.2e-07 30.0 0.0 5.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain ODV-E18 PF10717.4 EDN10703.1 - 0.15 11.5 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 FANCAA PF15146.1 EDN10704.1 - 0.071 12.0 0.1 0.076 11.9 0.1 1.1 1 0 0 1 1 1 0 Fanconi anemia-associated DUF3901 PF13040.1 EDN10706.1 - 0.053 12.8 0.8 0.068 12.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3901) BRO1 PF03097.13 EDN10707.1 - 1.2e-55 188.8 0.5 8.6e-34 116.8 0.0 2.7 2 1 1 3 3 3 2 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EDN10707.1 - 2.6e-48 164.5 7.6 5.1e-48 163.5 5.3 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV CTDII PF01556.13 EDN10708.1 - 4.2e-32 109.8 3.3 1.4e-22 79.3 0.2 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EDN10708.1 - 1.2e-10 41.2 20.7 3e-10 40.0 14.3 1.7 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EDN10708.1 - 0.075 12.7 8.4 0.29 10.8 1.0 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Lon_C PF05362.8 EDN10709.1 - 7.8e-63 211.4 0.0 2e-62 210.1 0.0 1.7 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EDN10709.1 - 7.9e-40 136.7 0.2 7.9e-40 136.7 0.1 2.1 3 0 0 3 3 3 1 ATP-dependent protease La (LON) domain ChlI PF13541.1 EDN10709.1 - 2e-05 24.1 0.0 4.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Pkinase PF00069.20 EDN10710.1 - 1.2e-10 40.9 0.0 2.2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN10710.1 - 2.4e-07 30.0 0.0 4.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDN10710.1 - 0.077 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mob1_phocein PF03637.12 EDN10711.1 - 5.7e-26 91.2 0.1 8.4e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family cobW PF02492.14 EDN10712.1 - 3.8e-28 98.1 0.1 5.4e-28 97.6 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain HAUS6_N PF14661.1 EDN10713.1 - 8.9e-64 215.2 0.4 8.9e-64 215.2 0.2 1.6 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus HD_3 PF13023.1 EDN10714.1 - 1.8e-46 157.8 0.1 2.3e-46 157.5 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EDN10714.1 - 0.057 13.4 0.2 0.14 12.2 0.1 1.6 1 1 0 1 1 1 0 HD domain HIT PF01230.18 EDN10715.1 - 2.8e-24 85.5 0.1 7.1e-24 84.1 0.0 1.7 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EDN10715.1 - 0.00013 22.1 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Rad4 PF03835.10 EDN10716.1 - 1.4e-32 112.0 0.3 4.2e-32 110.5 0.0 1.9 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EDN10716.1 - 2e-28 97.9 0.1 4.6e-28 96.7 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EDN10716.1 - 1e-18 66.5 0.1 2.3e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EDN10716.1 - 3.7e-18 65.6 2.9 1.6e-17 63.5 0.0 3.0 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EDN10716.1 - 0.00098 19.3 0.0 0.0033 17.6 0.0 2.0 1 0 0 1 1 1 1 Transglutaminase-like superfamily NOA36 PF06524.7 EDN10716.1 - 1.2 8.2 11.4 2.4 7.3 7.9 1.4 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 EDN10716.1 - 1.9 8.2 7.2 6.9 6.4 5.0 2.0 1 0 0 1 1 1 0 RXT2-like, N-terminal CoA_binding_2 PF13380.1 EDN10717.1 - 1.8e-27 95.8 0.0 3.4e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 CoA binding domain Phage_int_SAM_1 PF02899.12 EDN10718.1 - 0.0013 18.8 0.1 0.031 14.4 0.1 2.3 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Dot_icm_IcmQ PF09475.5 EDN10719.1 - 0.025 13.8 0.5 0.035 13.3 0.4 1.3 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Suf PF05843.9 EDN10719.1 - 0.063 12.9 2.7 0.078 12.6 1.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med28 PF11594.3 EDN10719.1 - 9.7 6.4 9.6 35 4.6 5.8 2.2 1 1 1 2 2 2 0 Mediator complex subunit 28 DUF3716 PF12511.3 EDN10720.1 - 7.4e-19 67.1 2.1 9.7e-19 66.7 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Fungal_trans PF04082.13 EDN10721.1 - 2.4e-17 62.6 1.2 4.1e-17 61.9 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN10721.1 - 2.4e-10 40.1 8.3 3.9e-10 39.4 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EDN10721.1 - 0.0027 16.3 0.3 0.0097 14.5 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 EDN10722.1 - 9.7e-53 178.4 26.7 2.4e-34 118.3 3.5 3.3 2 1 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.7 EDN10722.1 - 1.5e-24 85.6 1.9 3.2e-24 84.5 0.0 2.3 2 0 0 2 2 2 1 CDR ABC transporter ABC_tran PF00005.22 EDN10722.1 - 3e-22 79.3 0.0 3.4e-17 63.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 EDN10722.1 - 0.00012 21.3 0.5 0.00036 19.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EDN10722.1 - 0.00087 18.7 0.1 0.0022 17.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EDN10722.1 - 0.005 16.7 0.1 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EDN10722.1 - 0.007 15.8 0.8 0.019 14.5 0.6 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EDN10722.1 - 0.0089 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EDN10722.1 - 0.012 15.6 0.3 0.46 10.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EDN10722.1 - 0.015 15.3 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 EDN10722.1 - 0.028 13.8 0.6 0.054 12.9 0.4 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EDN10722.1 - 0.036 14.2 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EDN10722.1 - 0.13 11.2 0.0 0.32 9.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EDN10722.1 - 0.17 12.2 2.6 1.2 9.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Fungal_trans_2 PF11951.3 EDN10723.1 - 6.5e-09 34.8 0.3 2.3e-07 29.7 0.0 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN10723.1 - 1.9e-06 27.6 7.4 1.9e-06 27.6 5.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWC PF00093.13 EDN10723.1 - 5.5 7.1 11.5 4.5 7.4 0.2 2.7 3 0 0 3 3 3 0 von Willebrand factor type C domain Chitin_bind_3 PF03067.10 EDN10724.1 - 1e-07 32.3 0.0 1.4e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Chitin binding domain MFS_1 PF07690.11 EDN10725.1 - 5.5e-33 114.1 16.9 6.3e-33 113.9 9.7 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.23 EDN10726.1 - 5.9e-74 248.9 0.1 7.1e-74 248.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN10726.1 - 2.2e-08 34.9 0.8 4.3e-08 33.9 0.2 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CarboxypepD_reg PF13620.1 EDN10726.1 - 0.1 12.6 2.8 0.2 11.7 0.0 2.9 4 0 0 4 4 4 0 Carboxypeptidase regulatory-like domain CAP_N PF01213.14 EDN10727.1 - 8.8 5.5 9.1 17 4.5 6.3 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Sugar_tr PF00083.19 EDN10728.1 - 1.9e-12 46.5 4.1 2.5e-12 46.1 2.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN10728.1 - 1e-06 27.7 0.1 1.3e-06 27.3 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF998 PF06197.8 EDN10728.1 - 0.041 13.2 3.3 0.078 12.2 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF998) ABC_tran PF00005.22 EDN10729.1 - 3e-28 98.8 0.0 2.9e-26 92.4 0.0 2.5 1 1 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EDN10729.1 - 1.5e-16 60.6 7.7 7.8e-15 55.0 0.0 2.8 2 1 1 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EDN10729.1 - 2.1e-08 33.6 0.0 5.3e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDN10729.1 - 3.9e-05 23.7 0.0 0.0044 17.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDN10729.1 - 0.00047 20.2 0.0 0.006 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EDN10729.1 - 0.00057 19.3 0.1 0.0012 18.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EDN10729.1 - 0.0023 17.1 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EDN10729.1 - 0.0061 16.9 0.2 0.0061 16.9 0.1 2.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EDN10729.1 - 0.021 14.8 0.1 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 EDN10729.1 - 0.054 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EDN10729.1 - 0.057 13.6 0.2 8.5 6.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EDN10729.1 - 0.083 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EDN10729.1 - 0.12 13.1 0.0 0.29 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cu_amine_oxid PF01179.15 EDN10730.1 - 5e-134 447.1 3.7 2.5e-100 336.1 0.5 2.0 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EDN10730.1 - 3.4e-06 27.0 0.1 6.6e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EDN10730.1 - 8.1e-05 22.6 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain UQ_con PF00179.21 EDN10732.1 - 1e-39 135.1 0.0 1.2e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDN10732.1 - 0.00036 20.3 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.6 EDN10732.1 - 0.089 12.2 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.17 EDN10732.1 - 0.1 12.5 0.7 0.18 11.6 0.5 1.7 1 1 0 1 1 1 0 RWD domain HhH-GPD PF00730.20 EDN10733.1 - 3.4e-19 69.1 0.0 2e-17 63.4 0.0 3.0 3 0 0 3 3 3 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EDN10733.1 - 8.8e-08 31.4 0.0 1.3e-06 27.7 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif AAA_11 PF13086.1 EDN10734.1 - 1.3e-60 204.9 0.5 2.7e-60 203.8 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EDN10734.1 - 4.7e-57 192.6 0.0 7.1e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN10734.1 - 3.2e-13 49.2 0.1 1.3e-11 44.0 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EDN10734.1 - 2e-10 40.5 0.0 1e-08 34.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EDN10734.1 - 1.6e-07 31.1 0.0 0.11 11.9 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EDN10734.1 - 3.2e-06 26.3 0.0 1.7e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EDN10734.1 - 3.8e-06 26.8 0.0 1.7e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C PF13361.1 EDN10734.1 - 9.4e-06 25.3 0.0 0.088 12.2 0.0 3.1 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EDN10734.1 - 2.2e-05 24.6 0.1 0.0012 19.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 EDN10734.1 - 0.00011 21.4 0.0 0.0083 15.3 0.0 2.6 3 0 0 3 3 3 1 PhoH-like protein UvrD-helicase PF00580.16 EDN10734.1 - 0.00018 20.9 0.0 0.0022 17.3 0.0 2.0 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EDN10734.1 - 0.0059 16.2 0.0 0.33 10.5 0.0 2.5 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.1 EDN10734.1 - 0.0062 16.5 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EDN10734.1 - 0.0064 15.4 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_5 PF07728.9 EDN10734.1 - 0.0067 16.1 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zot PF05707.7 EDN10734.1 - 0.0079 15.6 0.1 0.046 13.1 0.0 2.3 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) Flavi_DEAD PF07652.9 EDN10734.1 - 0.0089 15.7 0.0 0.065 12.9 0.0 2.1 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_25 PF13481.1 EDN10734.1 - 0.0096 15.3 0.0 0.034 13.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EDN10734.1 - 0.016 15.3 0.0 0.069 13.3 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EDN10734.1 - 0.029 13.8 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EDN10734.1 - 0.034 13.5 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EDN10734.1 - 0.039 13.4 0.0 0.089 12.2 0.0 1.6 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 EDN10734.1 - 0.13 12.1 0.0 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.1 EDN10734.1 - 0.13 12.3 0.0 2.2 8.4 0.0 2.7 3 0 0 3 3 2 0 UvrD-like helicase C-terminal domain RVT_2 PF07727.9 EDN10736.1 - 6e-57 192.4 0.0 7.9e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_12 PF13087.1 EDN10737.1 - 1.8e-33 115.6 0.0 3.9e-33 114.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.1 EDN10737.1 - 0.0038 16.7 0.0 0.45 9.9 0.0 2.1 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 EDN10737.1 - 0.09 12.2 0.0 0.15 11.5 0.0 1.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 EDN10737.1 - 0.093 12.8 0.0 0.31 11.1 0.0 1.7 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain Aldo_ket_red PF00248.16 EDN10738.1 - 2e-23 82.6 0.0 2.7e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Oxidored_molyb PF00174.14 EDN10739.1 - 3.3e-46 156.7 0.0 7.7e-46 155.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EDN10739.1 - 1.3e-35 121.8 1.3 4.4e-35 120.1 0.2 2.3 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.19 EDN10739.1 - 1.5e-17 63.5 0.0 3e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EDN10739.1 - 8.8e-17 60.6 0.1 2.8e-16 59.0 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 EDN10739.1 - 1.7e-16 60.7 0.0 7.3e-16 58.6 0.0 2.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EDN10739.1 - 0.027 14.3 0.2 0.12 12.3 0.0 2.2 2 1 1 3 3 3 0 Ferric reductase NAD binding domain FAINT PF04385.10 EDN10740.1 - 0.023 14.5 0.0 1.8 8.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function, DUF529 ATP-grasp_4 PF13535.1 EDN10740.1 - 0.064 12.9 0.0 3.4 7.3 0.0 2.8 3 0 0 3 3 3 0 ATP-grasp domain Sugar_tr PF00083.19 EDN10741.1 - 3e-56 190.8 11.1 3.4e-56 190.7 7.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN10741.1 - 3.5e-07 29.2 20.3 8.8e-05 21.3 10.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tetraspannin PF00335.15 EDN10741.1 - 0.11 11.7 8.1 0.23 10.7 5.6 1.5 1 0 0 1 1 1 0 Tetraspanin family LLC1 PF14945.1 EDN10742.1 - 0.84 9.9 4.1 0.97 9.7 2.4 1.4 1 1 1 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein RhoGAP PF00620.22 EDN10743.1 - 5.5e-36 123.4 0.0 9.8e-36 122.6 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Med7 PF05983.6 EDN10743.1 - 0.0052 16.5 0.1 0.0089 15.8 0.1 1.3 1 0 0 1 1 1 1 MED7 protein Beta_elim_lyase PF01212.16 EDN10744.1 - 3.6e-62 210.1 0.0 4.9e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EDN10744.1 - 6.1e-05 22.2 0.0 0.0044 16.1 0.0 2.6 2 1 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EDN10744.1 - 0.017 13.3 0.0 0.1 10.8 0.0 1.9 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme ADH_N PF08240.7 EDN10745.1 - 1.1e-20 73.4 0.5 3.1e-20 71.9 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDN10745.1 - 1.2e-18 66.8 0.4 8.4e-18 64.1 0.3 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EDN10745.1 - 0.01 15.2 0.3 0.017 14.4 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 EDN10745.1 - 0.1 12.3 2.9 1.1 9.1 1.1 2.4 1 1 1 2 2 2 0 ThiF family RRN7 PF11781.3 EDN10746.1 - 0.19 11.2 1.2 16 5.1 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 LIM PF00412.17 EDN10746.1 - 0.38 10.8 1.4 0.67 10.0 0.1 1.8 2 0 0 2 2 2 0 LIM domain DEAD PF00270.24 EDN10747.1 - 1.2e-34 119.2 0.2 1.3e-33 115.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN10747.1 - 1.2e-21 76.3 0.3 2.6e-21 75.2 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GABP-alpha PF11620.3 EDN10747.1 - 0.062 13.2 0.1 0.62 10.0 0.0 2.5 2 0 0 2 2 2 0 GA-binding protein alpha chain CMS1 PF14617.1 EDN10747.1 - 0.065 12.2 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF3217 PF11506.3 EDN10747.1 - 0.085 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3217) tRNA-synt_1b PF00579.20 EDN10747.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) SH3_9 PF14604.1 EDN10748.1 - 2.7e-24 84.4 0.4 3.3e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 EDN10748.1 - 3.5e-22 78.3 0.0 3.5e-22 78.3 0.0 2.4 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EDN10748.1 - 3.1e-17 61.6 0.2 2.1e-07 30.2 0.1 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 EDN10748.1 - 1.7e-14 53.2 5.2 2.8e-14 52.5 3.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 EDN10748.1 - 0.00026 20.4 0.2 0.18 11.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain Ax_dynein_light PF10211.4 EDN10748.1 - 0.0061 16.4 3.2 0.0061 16.4 2.2 2.5 2 0 0 2 2 2 1 Axonemal dynein light chain SH3_3 PF08239.6 EDN10748.1 - 0.053 13.7 0.4 0.65 10.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain C1_2 PF03107.11 EDN10748.1 - 0.57 10.3 7.8 1 9.5 5.4 1.4 1 0 0 1 1 1 0 C1 domain Glyco_hydro_72 PF03198.9 EDN10749.1 - 4.9e-129 429.8 0.7 6.1e-129 429.5 0.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EDN10749.1 - 2.1e-06 27.1 0.2 8.4e-06 25.1 0.1 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GAF_2 PF13185.1 EDN10750.1 - 0.0025 18.3 0.0 0.0031 17.9 0.0 1.1 1 0 0 1 1 1 1 GAF domain NAD_kinase PF01513.16 EDN10751.1 - 3.5e-67 226.1 0.0 4e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 ATP-NAD kinase Amnionless PF14828.1 EDN10752.1 - 0.1 11.1 0.0 0.1 11.0 0.0 1.0 1 0 0 1 1 1 0 Amnionless RNase_PH PF01138.16 EDN10753.1 - 0.0022 18.2 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 E1-E2_ATPase PF00122.15 EDN10754.1 - 9e-62 208.1 9.4 9e-62 208.1 6.5 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EDN10754.1 - 1e-28 101.2 0.0 4.1e-28 99.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDN10754.1 - 9.8e-16 56.9 0.0 2.5e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EDN10754.1 - 5.7e-14 51.8 0.0 1.1e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EDN10754.1 - 1.7e-11 44.6 0.1 7.6e-11 42.5 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDN10754.1 - 6.3e-06 25.9 4.4 1.9e-05 24.3 1.7 2.2 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EDN10755.1 - 5.1e-18 65.2 3.3 7.2e-18 64.7 2.3 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus CitMHS PF03600.11 EDN10755.1 - 0.072 11.6 2.5 0.097 11.2 1.7 1.2 1 0 0 1 1 1 0 Citrate transporter DUF2014 PF09427.5 EDN10757.1 - 3.4e-114 380.3 0.9 4.5e-114 379.9 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EDN10757.1 - 4.3e-18 64.7 0.5 1.5e-17 63.0 0.4 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 EDN10757.1 - 0.34 10.9 7.1 0.1 12.5 2.4 1.9 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 EDN10757.1 - 0.47 10.3 6.0 0.39 10.5 2.2 2.0 2 0 0 2 2 2 0 Basic region leucine zipper TSC22 PF01166.13 EDN10757.1 - 0.87 9.5 3.0 1.6 8.7 1.2 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family DHDPS PF00701.17 EDN10758.1 - 7.1e-43 146.2 0.0 8.6e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF4470 PF14737.1 EDN10759.1 - 1.9e-17 62.8 0.0 5.2e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EDN10759.1 - 2.8e-09 36.7 14.0 6.9e-09 35.4 9.7 1.7 1 0 0 1 1 1 1 MYND finger MFS_1 PF07690.11 EDN10760.1 - 2.1e-20 72.7 25.9 1.4e-11 43.7 9.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily CRPA PF05745.6 EDN10760.1 - 0.57 9.9 8.1 0.088 12.6 1.7 2.1 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Pectate_lyase_3 PF12708.2 EDN10761.1 - 8e-38 130.7 8.3 8e-38 130.7 5.8 3.0 4 0 0 4 4 4 1 Pectate lyase superfamily protein Varsurf_PPLC PF03490.8 EDN10761.1 - 0.00019 21.0 0.2 0.00051 19.6 0.1 1.6 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C GBP_repeat PF02526.9 EDN10761.1 - 0.1 11.9 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Glycophorin-binding protein ARL6IP6 PF15062.1 EDN10763.1 - 5.3 7.0 6.4 1.1 9.1 0.7 2.5 2 1 0 2 2 2 0 Haemopoietic lineage transmembrane helix Mito_carr PF00153.22 EDN10764.1 - 3.3e-30 103.6 0.1 1.2e-19 69.7 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein PepSY_TM_1 PF13172.1 EDN10764.1 - 3.2 7.6 6.7 10 6.0 0.2 2.7 2 0 0 2 2 2 0 PepSY-associated TM helix Pex24p PF06398.6 EDN10766.1 - 3.8e-57 193.7 0.0 4.7e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Fig1 PF12351.3 EDN10766.1 - 0.037 13.9 0.2 0.06 13.2 0.1 1.3 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 RVT_2 PF07727.9 EDN10767.1 - 1.9e-40 138.4 0.0 4.9e-38 130.4 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN10767.1 - 8.8e-16 58.0 0.0 2.2e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF4219 PF13961.1 EDN10767.1 - 0.024 14.0 1.9 0.051 13.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) gag_pre-integrs PF13976.1 EDN10767.1 - 0.027 14.1 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain Blt1 PF12754.2 EDN10768.1 - 4.1e-65 220.4 3.3 1.9e-64 218.2 2.3 1.7 1 1 0 1 1 1 1 Cell-cycle control medial ring component DUF4019 PF13211.1 EDN10768.1 - 0.095 12.9 0.4 0.21 11.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) Nop16 PF09420.5 EDN10770.1 - 1.1e-59 201.1 7.9 1.6e-59 200.6 5.5 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF2348 PF09807.4 EDN10772.1 - 0.019 14.0 0.1 0.021 13.9 0.0 1.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2348) APH_6_hur PF04655.9 EDN10772.1 - 0.058 12.5 0.1 0.061 12.4 0.1 1.1 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase RdRP PF05183.7 EDN10773.1 - 8.3e-89 298.8 0.1 1.2e-88 298.2 0.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase FAD-oxidase_C PF02913.14 EDN10774.1 - 1.4e-60 204.6 0.0 2e-60 204.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EDN10774.1 - 5.2e-35 119.9 0.0 1.1e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Ribosomal_S4e PF00900.15 EDN10776.1 - 2.1e-32 110.6 0.3 4.5e-32 109.5 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EDN10776.1 - 1.2e-18 66.6 4.9 2.3e-18 65.7 3.4 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EDN10776.1 - 1.4e-05 24.4 0.0 2.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EDN10776.1 - 0.001 18.7 0.7 0.001 18.7 0.5 3.2 4 0 0 4 4 4 1 KOW motif BCD PF15461.1 EDN10777.1 - 0.0099 15.3 3.1 0.014 14.8 2.2 1.1 1 0 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase 7tm_1 PF00001.16 EDN10777.1 - 0.044 12.9 0.9 3.1 6.8 0.1 2.0 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Myb_DNA-bind_6 PF13921.1 EDN10778.1 - 1.3e-11 44.4 0.4 4.5e-05 23.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN10778.1 - 8.6e-08 32.1 2.0 1.6e-05 24.8 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain PX PF00787.19 EDN10779.1 - 1.3e-26 92.6 0.2 1.5e-26 92.4 0.1 1.1 1 0 0 1 1 1 1 PX domain FAM91_N PF14647.1 EDN10779.1 - 0.059 12.4 0.0 0.073 12.1 0.0 1.1 1 0 0 1 1 1 0 FAM91 N-terminus WD40 PF00400.27 EDN10780.1 - 1.2e-21 75.6 24.5 8.8e-08 31.7 0.2 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EDN10780.1 - 0.015 13.6 6.4 0.14 10.3 0.2 3.9 3 1 1 5 5 5 0 Cytochrome D1 heme domain PD40 PF07676.7 EDN10780.1 - 0.22 11.2 0.1 0.22 11.2 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat SecE PF00584.15 EDN10781.1 - 1.1e-12 47.2 0.0 1.3e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_6 PF14259.1 EDN10782.1 - 2.3e-09 37.0 0.0 4.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN10782.1 - 1.1e-05 25.0 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN10782.1 - 0.041 13.7 0.1 0.079 12.8 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_3 PF13738.1 EDN10783.1 - 1.2e-15 58.0 0.1 2e-09 37.8 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN10783.1 - 2.5e-05 24.2 0.0 0.00023 21.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EDN10783.1 - 0.00015 20.9 0.0 0.00021 20.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.14 EDN10783.1 - 0.00065 18.0 0.7 0.077 11.1 0.0 2.4 2 1 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EDN10783.1 - 0.0016 18.3 0.0 0.095 12.5 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDN10783.1 - 0.0023 16.8 0.0 0.25 10.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EDN10783.1 - 0.0066 16.8 0.0 0.57 10.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDN10783.1 - 0.014 14.3 0.0 0.064 12.1 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EDN10783.1 - 0.021 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EDN10783.1 - 0.025 13.6 0.0 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.1 EDN10783.1 - 0.034 14.3 0.0 0.96 9.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EDN10783.1 - 0.049 13.7 0.0 6.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EDN10783.1 - 0.069 11.6 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EDN10783.1 - 0.083 12.6 0.0 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EDN10783.1 - 0.16 10.7 0.0 0.29 9.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EDN10783.1 - 0.25 10.1 0.0 1.1 8.0 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Toxin_21 PF08091.6 EDN10784.1 - 0.089 12.5 0.3 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Spider insecticidal peptide Mito_carr PF00153.22 EDN10786.1 - 1.5e-77 255.3 1.7 2.8e-25 87.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L21e PF01157.13 EDN10787.1 - 2.1e-23 81.9 1.7 2.1e-23 81.9 1.2 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e Ribosomal_S4 PF00163.14 EDN10788.1 - 1e-29 102.7 1.3 1.7e-29 102.0 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EDN10788.1 - 8.2e-13 47.5 1.4 8.2e-13 47.5 1.0 2.6 4 0 0 4 4 4 1 S4 domain MIP-T3 PF10243.4 EDN10789.1 - 9.3 4.5 39.3 13 4.1 27.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DOPA_dioxygen PF08883.6 EDN10790.1 - 2.7e-31 107.7 0.0 3.5e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DUF946 PF06101.6 EDN10791.1 - 6.1e-16 57.5 2.2 1.5e-10 39.7 0.5 2.0 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) NPP1 PF05630.6 EDN10791.1 - 0.0064 16.2 0.1 0.0082 15.8 0.1 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) YcfA PF07927.7 EDN10791.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 YcfA-like protein FtsK_SpoIIIE PF01580.13 EDN10792.1 - 0.00096 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.15 EDN10792.1 - 0.02 13.6 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Dynamin_N PF00350.18 EDN10792.1 - 0.048 13.4 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.1 EDN10792.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF4527 PF15030.1 EDN10794.1 - 0.097 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) Myb_DNA-binding PF00249.26 EDN10795.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF484 PF04340.7 EDN10795.1 - 0.078 12.4 0.3 0.17 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF484 UPF0016 PF01169.14 EDN10796.1 - 9.4e-40 134.6 25.8 1.6e-21 76.2 5.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF4611 PF15387.1 EDN10797.1 - 0.099 12.8 1.9 0.34 11.0 1.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.1 EDN10797.1 - 0.94 9.8 6.6 0.48 10.7 2.5 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 EDN10797.1 - 1.7 7.8 5.2 2.6 7.2 3.6 1.2 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.11 EDN10798.1 - 1.7e-18 66.5 22.0 9.7e-10 37.6 2.7 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN10798.1 - 9.3e-06 24.4 2.6 9.3e-06 24.4 1.8 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter DUF4118 PF13493.1 EDN10798.1 - 0.012 15.7 3.1 0.012 15.7 2.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4118) Gln-synt_C PF00120.19 EDN10799.1 - 3.1e-43 147.7 0.0 7.8e-43 146.4 0.0 1.7 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EDN10799.1 - 9.2e-30 104.1 0.0 1.6e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 EDN10799.1 - 0.0016 17.6 0.0 0.0077 15.4 0.0 2.1 2 0 0 2 2 2 1 TatD related DNase Aldedh PF00171.17 EDN10800.1 - 1.2e-124 416.1 0.7 2.3e-80 270.2 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family AA_permease_2 PF13520.1 EDN10801.1 - 1.2e-12 47.0 6.6 1.6e-12 46.6 4.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDN10801.1 - 1.8e-05 23.2 7.0 2.3e-05 22.9 4.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF998 PF06197.8 EDN10801.1 - 0.2 10.9 8.5 0.8 8.9 5.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Form_Nir_trans PF01226.12 EDN10801.1 - 0.27 10.1 8.5 0.16 10.8 3.7 2.0 2 0 0 2 2 2 0 Formate/nitrite transporter DUF4149 PF13664.1 EDN10801.1 - 2.8 8.0 6.7 0.79 9.8 0.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) UDPGP PF01704.13 EDN10802.1 - 3.6 5.9 8.3 1.5e+02 0.6 0.0 5.9 2 1 7 9 9 9 0 UTP--glucose-1-phosphate uridylyltransferase Ground-like PF04155.13 EDN10802.1 - 4.4 7.6 4.9 18 5.7 0.7 3.0 2 0 0 2 2 2 0 Ground-like domain Fumble PF03630.9 EDN10803.1 - 4.9e-132 439.9 0.3 5.7e-131 436.4 0.2 1.9 1 1 0 1 1 1 1 Fumble GPI2 PF06432.6 EDN10804.1 - 1e-59 202.2 1.9 1e-59 202.2 1.3 2.0 2 0 0 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase Glyoxal_oxid_N PF07250.6 EDN10805.1 - 5.9e-43 146.6 0.0 3.8e-41 140.7 0.0 2.7 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EDN10805.1 - 2.5e-22 78.7 0.1 4.7e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) RCC1_2 PF13540.1 EDN10805.1 - 0.056 13.0 0.0 1.6 8.4 0.0 3.2 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat DEAD PF00270.24 EDN10806.1 - 8.6e-42 142.4 0.0 2e-41 141.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN10806.1 - 6.8e-22 77.1 0.1 6.8e-22 77.1 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDN10806.1 - 5.1e-05 22.2 0.0 7.8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 EDN10806.1 - 0.023 13.1 0.0 0.16 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) ResIII PF04851.10 EDN10806.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EDN10806.1 - 0.085 12.1 0.0 5.5 6.2 0.0 2.1 2 0 0 2 2 2 0 SecA DEAD-like domain Polysacc_deac_1 PF01522.16 EDN10807.1 - 1.2e-19 70.2 0.0 1.9e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DFP PF04127.10 EDN10808.1 - 6.3e-13 48.7 0.0 2.7e-05 23.8 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein Herpes_UL6 PF01763.11 EDN10810.1 - 0.024 12.8 5.1 0.033 12.3 3.4 1.4 1 1 0 1 1 1 0 Herpesvirus UL6 like CENP-O PF09496.5 EDN10811.1 - 1.3e-31 108.6 0.1 2.5e-31 107.7 0.1 1.5 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Acetyltransf_3 PF13302.1 EDN10812.1 - 2.6e-36 124.9 0.0 3e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDN10812.1 - 0.00039 20.3 0.1 0.0024 17.8 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family STAG PF08514.6 EDN10813.1 - 1.2e-35 121.8 2.2 1.2e-35 121.8 1.5 2.1 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.1 EDN10813.1 - 1.4e-06 28.4 0.2 0.031 14.5 0.0 3.4 4 0 0 4 4 4 2 HEAT repeats Nop14 PF04147.7 EDN10813.1 - 0.0005 18.1 18.6 0.0005 18.1 12.9 3.6 3 1 0 3 3 3 1 Nop14-like family HEAT PF02985.17 EDN10813.1 - 0.00074 19.3 0.0 5.7 7.3 0.0 4.4 3 0 0 3 3 3 1 HEAT repeat CENP-T PF15511.1 EDN10813.1 - 0.031 13.5 34.7 0.094 11.9 12.3 4.2 4 0 0 4 4 4 0 Centromere kinetochore component CENP-T DUF422 PF04240.7 EDN10813.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF422) Acatn PF13000.2 EDN10814.1 - 5.5e-102 342.0 18.1 4e-48 164.2 1.8 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 UreD PF01774.12 EDN10815.1 - 1.5e-49 168.3 0.0 1.9e-48 164.7 0.0 2.0 1 1 0 1 1 1 1 UreD urease accessory protein GDPD_2 PF13653.1 EDN10816.1 - 0.098 12.8 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family S1 PF00575.18 EDN10818.1 - 2.4e-25 88.4 3.6 7.6e-14 51.5 0.5 2.5 2 0 0 2 2 2 2 S1 RNA binding domain TPR_14 PF13428.1 EDN10818.1 - 7.5e-08 32.3 0.0 6 7.8 0.0 5.6 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN10818.1 - 2.6e-07 30.8 0.0 0.7 10.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDN10818.1 - 1.8e-06 28.4 0.0 3.1 8.5 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat PPR PF01535.15 EDN10818.1 - 7.2e-06 25.6 0.4 1 9.4 0.0 3.9 3 0 0 3 3 3 2 PPR repeat Suf PF05843.9 EDN10818.1 - 1.8e-05 24.6 1.5 0.11 12.2 0.1 3.4 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EDN10818.1 - 0.0016 18.0 0.1 0.23 11.1 0.0 2.7 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.1 EDN10818.1 - 0.0017 18.0 0.1 0.31 10.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDN10818.1 - 0.002 18.4 0.3 28 5.4 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDN10818.1 - 0.018 14.8 1.8 5.4 7.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_2 PF13041.1 EDN10818.1 - 0.02 14.8 0.0 36 4.4 0.0 3.4 3 0 0 3 3 3 0 PPR repeat family RNA_bind_2 PF10133.4 EDN10818.1 - 0.024 14.6 0.4 0.081 12.9 0.3 1.9 1 0 0 1 1 1 0 Predicted RNA-binding protein TPR_12 PF13424.1 EDN10818.1 - 0.04 13.8 0.1 30 4.6 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDN10818.1 - 0.16 11.8 1.5 0.96 9.3 0.0 3.0 4 0 0 4 4 2 0 Tetratricopeptide repeat S1 PF00575.18 EDN10819.1 - 1.2e-28 98.9 8.1 2.5e-10 40.3 0.0 6.3 6 1 0 6 6 6 5 S1 RNA binding domain WD40 PF00400.27 EDN10820.1 - 1.6e-25 88.0 7.9 7.9e-07 28.7 0.1 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EDN10820.1 - 9.5e-06 24.0 0.3 0.0014 16.8 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF3374 PF11854.3 EDN10820.1 - 0.069 11.3 0.1 0.093 10.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3374) Cpn60_TCP1 PF00118.19 EDN10821.1 - 1.7e-142 475.4 16.4 2e-142 475.2 11.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2b PF00587.20 EDN10822.1 - 2.3e-21 76.1 0.1 3.6e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 EDN10822.1 - 8.4e-18 64.0 2.6 2e-17 62.8 1.8 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal DUF1590 PF07629.6 EDN10824.1 - 0.033 13.7 0.2 0.08 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) PEMT PF04191.8 EDN10827.1 - 6.8e-16 58.2 2.7 6.8e-16 58.2 1.9 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase MFS_1 PF07690.11 EDN10829.1 - 1.9e-13 49.8 25.0 3.5e-13 49.0 17.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PRKCSH-like PF12999.2 EDN10829.1 - 0.23 11.0 0.0 0.5 9.9 0.0 1.6 1 0 0 1 1 1 0 Glucosidase II beta subunit-like DUF3792 PF12670.2 EDN10829.1 - 1.4 8.8 13.4 0.27 11.1 4.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) p450 PF00067.17 EDN10830.1 - 4.1e-23 81.6 0.0 8.7e-22 77.2 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Arginase PF00491.16 EDN10831.1 - 1.8e-13 50.4 0.7 1.3e-09 37.7 0.1 2.1 1 1 1 2 2 2 2 Arginase family Arginase PF00491.16 EDN10832.1 - 6.7e-18 64.9 0.0 9.1e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Arginase family DUF1993 PF09351.5 EDN10833.1 - 1.2e-35 122.8 0.1 3.3e-22 79.1 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF1993) ketoacyl-synt PF00109.21 EDN10834.1 - 2.9e-56 190.7 1.6 3.5e-55 187.2 0.2 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EDN10834.1 - 6.6e-33 113.0 1.9 7.6e-33 112.8 0.3 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EDN10834.1 - 2e-05 23.6 0.2 5.8e-05 22.2 0.2 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDN10834.1 - 0.0055 16.1 2.5 0.22 10.9 0.3 3.5 3 1 0 3 3 3 1 Thiolase, C-terminal domain SCA7 PF08313.7 EDN10835.1 - 1.8e-33 113.9 0.8 1.8e-33 113.9 0.6 1.8 2 0 0 2 2 2 1 SCA7, zinc-binding domain DUF3505 PF12013.3 EDN10835.1 - 2.3 8.4 6.9 0.14 12.3 0.4 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) mRNA_cap_enzyme PF01331.14 EDN10836.1 - 1.9e-50 171.2 0.2 2.6e-50 170.8 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.16 EDN10836.1 - 6.8e-09 35.3 0.4 3.8e-07 29.6 0.3 2.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain mRNA_cap_C PF03919.10 EDN10836.1 - 0.00019 21.6 0.1 0.002 18.4 0.0 2.6 1 1 1 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_N PF04675.9 EDN10837.1 - 1.1e-56 191.4 0.1 1.9e-56 190.6 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.16 EDN10837.1 - 3.3e-39 134.3 0.1 5.7e-39 133.5 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.10 EDN10837.1 - 2.3e-27 95.2 0.0 7.1e-27 93.6 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DUF4661 PF15576.1 EDN10837.1 - 3.6 7.1 8.7 7.2 6.1 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) CFEM PF05730.6 EDN10839.1 - 3.2e-09 36.4 6.0 4.8e-09 35.9 4.2 1.3 1 0 0 1 1 1 1 CFEM domain NPP PF08384.5 EDN10839.1 - 0.002 17.7 6.4 0.48 10.0 0.1 2.4 2 0 0 2 2 2 2 Pro-opiomelanocortin, N-terminal region Cu_amine_oxid PF01179.15 EDN10840.1 - 1.8e-91 306.9 0.7 2.5e-91 306.4 0.5 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EDN10840.1 - 3.3e-08 33.3 0.0 1e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EDN10840.1 - 0.026 14.6 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Mito_fiss_reg PF05308.6 EDN10841.1 - 0.074 12.4 3.9 0.17 11.2 2.7 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator eIF-5_eIF-2B PF01873.12 EDN10842.1 - 1.5e-38 131.2 0.0 2.4e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EDN10842.1 - 3.6e-25 87.7 0.2 9.1e-25 86.4 0.2 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon BLVR PF06375.6 EDN10842.1 - 0.062 13.1 11.8 0.027 14.3 5.4 2.2 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) TMP-TENI PF02581.12 EDN10843.1 - 3.4e-58 195.7 0.5 6.2e-58 194.8 0.3 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI HK PF02110.10 EDN10843.1 - 1.5e-56 191.3 0.1 3.1e-56 190.3 0.0 1.5 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Isochorismatase PF00857.15 EDN10844.1 - 3.7e-23 82.3 0.0 4.8e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Lipase_GDSL_2 PF13472.1 EDN10845.1 - 7.2e-20 71.8 0.0 9.3e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EDN10845.1 - 1.2e-11 44.9 0.0 3.5e-11 43.4 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EDN10845.1 - 0.0051 16.5 0.0 0.0083 15.8 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cwf_Cwc_15 PF04889.7 EDN10847.1 - 2.9e-68 230.2 9.9 3.8e-68 229.8 6.9 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 EDN10847.1 - 0.0011 18.4 6.6 0.0015 18.0 4.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Myc_N PF01056.13 EDN10847.1 - 0.11 11.6 7.5 0.16 11.1 5.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PA26 PF04636.8 EDN10847.1 - 0.27 9.8 2.0 0.3 9.7 1.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SDA1 PF05285.7 EDN10847.1 - 0.28 10.4 18.0 0.35 10.0 12.5 1.2 1 0 0 1 1 1 0 SDA1 APG6 PF04111.7 EDN10847.1 - 0.63 9.0 8.7 0.87 8.5 6.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Borrelia_P83 PF05262.6 EDN10847.1 - 1.3 7.2 10.3 1.6 6.9 7.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3381 PF11861.3 EDN10847.1 - 5.4 6.5 15.6 8.9 5.7 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CDC45 PF02724.9 EDN10847.1 - 8.1 4.3 15.2 10 3.9 10.5 1.1 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 EDN10847.1 - 8.8 6.3 8.5 17 5.3 5.9 1.4 1 0 0 1 1 1 0 YqfQ-like protein E1-E2_ATPase PF00122.15 EDN10848.1 - 2.1e-16 59.6 0.1 3.9e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EDN10848.1 - 1.9e-08 34.6 0.0 8.1e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDN10848.1 - 5e-05 23.8 0.0 0.00063 20.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDN10848.1 - 0.0068 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NicO PF03824.11 EDN10850.1 - 2.2e-26 92.8 19.5 4.3e-18 65.6 0.1 3.3 2 1 1 3 3 3 3 High-affinity nickel-transport protein Vma12 PF11712.3 EDN10850.1 - 0.054 13.2 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Peptidase_M14 PF00246.19 EDN10852.1 - 1.3e-69 234.8 0.0 1.7e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Nucleoplasmin PF03066.10 EDN10852.1 - 0.46 9.9 6.7 0.77 9.2 4.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EDN10852.1 - 7 6.2 9.6 11 5.5 6.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CorA PF01544.13 EDN10853.1 - 2.3e-07 30.1 0.0 4.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sec7 PF01369.15 EDN10854.1 - 1.9e-38 132.0 0.0 2.9e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain DUF4200 PF13863.1 EDN10857.1 - 0.028 14.3 0.5 0.059 13.3 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) SGT1 PF07093.6 EDN10857.1 - 2.9 6.1 14.3 4.9 5.3 9.9 1.3 1 1 0 1 1 1 0 SGT1 protein RVT_2 PF07727.9 EDN10858.1 - 2.3e-47 161.0 0.0 4e-27 94.7 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) gag_pre-integrs PF13976.1 EDN10858.1 - 1.7e-11 43.5 0.1 4.2e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 EDN10858.1 - 3.4e-06 27.1 0.0 1.5e-05 25.1 0.0 2.1 1 1 1 2 2 2 1 Integrase core domain DDE_1 PF03184.14 EDN10859.1 - 8.6e-29 100.2 0.0 1.6e-14 53.5 0.0 2.9 3 1 1 4 4 4 2 DDE superfamily endonuclease zf-CCHC_6 PF15288.1 EDN10859.1 - 0.025 14.2 0.3 0.31 10.7 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EDN10859.1 - 0.028 14.0 0.5 0.028 14.0 0.3 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EDN10859.1 - 0.19 11.7 1.0 0.33 10.9 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Defensin_2 PF01097.13 EDN10860.1 - 4.4e-07 29.5 3.2 7.3e-07 28.8 2.2 1.3 1 0 0 1 1 1 1 Arthropod defensin Toxin_3 PF00537.13 EDN10860.1 - 0.14 12.0 1.5 0.2 11.5 1.0 1.2 1 0 0 1 1 1 0 Scorpion toxin-like domain zf-C3HC4_2 PF13923.1 EDN10861.1 - 0.0036 17.3 0.8 0.0069 16.3 0.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Mating_C PF12737.2 EDN10861.1 - 0.029 13.2 1.8 0.044 12.6 1.3 1.3 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Atg14 PF10186.4 EDN10861.1 - 0.036 13.0 6.6 0.045 12.6 4.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Zip PF02535.17 EDN10863.1 - 1.6e-18 66.8 13.9 6e-18 64.9 9.6 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2040 PF09745.4 EDN10864.1 - 2.4e-39 134.0 19.4 2.4e-39 134.0 13.5 4.2 2 2 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Dispanin PF04505.7 EDN10864.1 - 1.1 8.8 3.5 4.9 6.7 0.3 2.6 2 0 0 2 2 2 0 Interferon-induced transmembrane protein AAA_23 PF13476.1 EDN10864.1 - 4.9 7.4 19.9 2 8.7 8.1 2.1 2 0 0 2 2 2 0 AAA domain Sedlin_N PF04628.8 EDN10865.1 - 5.2e-11 42.5 0.0 5.8e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Isochorismatase PF00857.15 EDN10867.1 - 1.6e-30 106.3 0.0 3.3e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Isochorismatase family FAR1 PF03101.10 EDN10867.1 - 7.3e-07 29.6 0.0 1.8e-06 28.4 0.0 1.6 2 0 0 2 2 2 1 FAR1 DNA-binding domain PriCT_2 PF08707.6 EDN10867.1 - 0.041 13.7 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) AFT PF08731.6 EDN10867.1 - 0.046 13.9 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT NUDE_C PF04880.8 EDN10868.1 - 8.7e-24 84.7 6.3 8.7e-24 84.7 4.4 2.6 2 1 1 3 3 2 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 EDN10868.1 - 0.00031 20.9 8.5 0.00031 20.9 5.9 3.6 1 1 2 3 3 3 1 Protein of unknown function (DUF904) WEMBL PF05701.6 EDN10868.1 - 0.00033 19.2 26.9 0.00044 18.8 18.7 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light ATG16 PF08614.6 EDN10868.1 - 0.013 15.3 16.1 0.013 15.3 11.2 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EDN10868.1 - 0.045 13.3 33.0 0.078 12.5 11.2 2.2 1 1 1 2 2 2 0 IncA protein ERM PF00769.14 EDN10868.1 - 0.05 13.1 25.0 0.012 15.1 2.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ADIP PF11559.3 EDN10868.1 - 0.36 10.7 29.7 4.1 7.2 7.1 3.4 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 EDN10868.1 - 0.45 10.3 31.4 8.3 6.2 18.0 2.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EDN10868.1 - 0.79 9.1 26.3 0.78 9.1 6.9 2.8 1 1 2 3 3 3 0 Intermediate filament protein LXG PF04740.7 EDN10868.1 - 0.99 9.1 17.6 0.22 11.2 2.6 2.6 1 1 2 3 3 3 0 LXG domain of WXG superfamily V_ATPase_I PF01496.14 EDN10868.1 - 1.9 6.2 19.3 3.7 5.2 4.1 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF3584 PF12128.3 EDN10868.1 - 4.1 4.6 24.7 5.4 4.2 17.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6 PF04111.7 EDN10868.1 - 4.3 6.2 32.5 0.49 9.3 12.5 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 HlyD_2 PF12700.2 EDN10868.1 - 4.5 6.3 15.6 1.2 8.1 8.8 1.4 1 1 0 1 1 1 0 HlyD family secretion protein AAA_13 PF13166.1 EDN10868.1 - 5.2 5.3 23.3 11 4.3 16.3 1.4 1 1 0 1 1 1 0 AAA domain IFT57 PF10498.4 EDN10868.1 - 5.9 5.5 22.5 0.075 11.7 7.1 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF972 PF06156.8 EDN10868.1 - 6.2 7.2 21.9 0.37 11.1 4.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF724 PF05266.9 EDN10868.1 - 7.7 6.0 24.0 1.7 8.2 7.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HALZ PF02183.13 EDN10868.1 - 8.1 6.2 13.9 0.89 9.3 0.5 3.5 3 1 0 3 3 3 0 Homeobox associated leucine zipper Tropomyosin_1 PF12718.2 EDN10868.1 - 8.5 6.2 33.9 2.1 8.2 13.4 3.2 1 1 1 2 2 2 0 Tropomyosin like ACC_central PF08326.7 EDN10869.1 - 1.3e-70 238.4 5.5 1.5e-39 135.7 0.1 3.1 1 1 2 3 3 3 2 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.12 EDN10869.1 - 6.1e-52 175.9 0.0 1.1e-51 175.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EDN10869.1 - 1.3e-21 76.5 0.0 9.8e-19 67.3 0.0 2.5 2 0 0 2 2 2 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EDN10869.1 - 6.3e-17 60.9 0.2 2.3e-16 59.1 0.0 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme CPSase_L_chain PF00289.17 EDN10869.1 - 1.2e-14 54.3 0.0 2.1e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EDN10869.1 - 5.4e-10 39.3 0.0 1.2e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EDN10869.1 - 2.9e-07 29.5 0.0 0.0049 15.6 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EDN10869.1 - 8.3e-05 22.0 0.0 0.00015 21.1 0.0 1.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EDN10869.1 - 0.00028 20.7 0.0 0.0013 18.6 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 EDN10869.1 - 0.037 13.3 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EDN10869.1 - 0.052 13.2 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 Biotin-lipoyl like HlyD_3 PF13437.1 EDN10869.1 - 0.13 12.5 0.1 5 7.5 0.0 2.7 2 0 0 2 2 2 0 HlyD family secretion protein Carboxyl_trans PF01039.17 EDN10870.1 - 4.5e-182 605.8 0.0 7.2e-182 605.1 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.7 EDN10870.1 - 3.6e-90 303.0 0.0 4.6e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region HeLo PF14479.1 EDN10871.1 - 0.005 16.6 0.7 0.027 14.2 0.5 2.0 1 1 1 2 2 2 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 EDN10871.1 - 0.011 14.8 0.0 0.03 13.3 0.0 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 EDN10871.1 - 0.025 13.7 0.0 0.061 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain Peptidase_S64 PF08192.6 EDN10871.1 - 3.1 5.9 6.9 1.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S64 DUF788 PF05620.6 EDN10874.1 - 8.5e-39 133.1 0.0 1.3e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Apc3 PF12895.2 EDN10875.1 - 1.3e-25 89.3 8.9 1.3e-22 79.6 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EDN10875.1 - 7.7e-22 75.9 3.9 1.6e-07 30.6 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EDN10875.1 - 1.1e-17 62.4 4.8 0.00053 19.7 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EDN10875.1 - 2.5e-15 55.8 10.9 0.00012 21.6 0.1 5.5 5 1 0 5 5 5 4 TPR repeat TPR_12 PF13424.1 EDN10875.1 - 2.9e-13 49.5 8.8 0.00014 21.7 0.0 5.0 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDN10875.1 - 7.7e-12 45.5 1.3 0.15 12.8 0.1 5.5 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EDN10875.1 - 9.2e-10 37.6 0.1 0.72 9.7 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDN10875.1 - 1.9e-07 30.3 2.1 0.036 13.8 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDN10875.1 - 2.2e-07 31.1 1.7 0.025 14.9 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDN10875.1 - 1.6e-06 28.2 1.8 22 6.0 0.0 6.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDN10875.1 - 7.3e-06 25.7 1.4 1.7 9.0 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDN10875.1 - 0.0044 17.3 6.5 2.7 8.6 0.0 5.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDN10876.1 - 2.9e-12 46.0 1.6 4e-07 29.5 0.1 2.2 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDN10876.1 - 5.8e-10 38.3 0.4 1.3e-06 27.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDN10876.1 - 1.2e-08 35.1 2.9 5.7e-07 29.7 0.5 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDN10876.1 - 1.8e-08 33.6 0.6 5.8e-06 25.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDN10876.1 - 1.4e-06 28.8 1.0 3.9e-05 24.2 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDN10876.1 - 1.9e-06 27.2 0.3 0.00023 20.7 0.0 3.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDN10876.1 - 3.7e-06 26.6 0.4 0.14 12.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDN10876.1 - 1.3e-05 25.4 1.0 0.098 13.3 0.0 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDN10876.1 - 0.0014 18.5 0.9 0.015 15.2 0.1 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EDN10876.1 - 0.0023 18.0 0.6 0.0038 17.3 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 APP_E2 PF12925.2 EDN10876.1 - 0.0057 16.2 0.3 0.0068 15.9 0.2 1.1 1 0 0 1 1 1 1 E2 domain of amyloid precursor protein TPR_6 PF13174.1 EDN10876.1 - 0.012 15.9 0.6 0.14 12.6 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EDN10876.1 - 0.017 14.9 0.4 1.3 8.9 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Ribos_L4_asso_C PF14374.1 EDN10876.1 - 0.04 13.7 0.7 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 60S ribosomal protein L4 C-terminal domain ChAPs PF09295.5 EDN10876.1 - 0.064 12.0 0.1 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF3245 PF11595.3 EDN10876.1 - 0.064 13.5 0.0 0.075 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) TPR_21 PF09976.4 EDN10876.1 - 0.12 12.2 0.2 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Acyltransferase PF01553.16 EDN10877.1 - 5.8e-32 109.9 0.0 1e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ACPS PF01648.15 EDN10878.1 - 3.3e-10 39.7 0.0 5.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SNO PF01174.14 EDN10879.1 - 1.5e-27 96.4 0.0 1.7e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EDN10879.1 - 4.1e-07 29.7 0.0 5.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DUF4066 PF13278.1 EDN10879.1 - 0.0022 17.2 0.0 0.0025 17.1 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EDN10879.1 - 0.0079 15.6 0.0 0.0092 15.4 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EDN10879.1 - 0.029 13.8 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 EDN10879.1 - 0.076 12.7 0.0 0.085 12.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S51 RRM_1 PF00076.17 EDN10880.1 - 3.9e-15 55.2 0.0 5.3e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN10880.1 - 7e-12 45.1 0.0 1e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN10880.1 - 1.4e-08 34.4 0.0 2.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TACC PF05010.9 EDN10881.1 - 0.054 13.2 0.0 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Rotamase PF00639.16 EDN10884.1 - 1.1e-21 77.3 0.0 1.6e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EDN10884.1 - 1.8e-14 54.0 0.0 2.2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EDN10884.1 - 5e-10 39.0 1.5 9.7e-10 38.1 1.0 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EDN10884.1 - 6.1e-05 23.6 0.0 8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain MAM PF00629.18 EDN10884.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.5 1 1 0 1 1 1 0 MAM domain MAPEG PF01124.13 EDN10885.1 - 1.7e-24 85.8 0.5 2.1e-24 85.5 0.4 1.1 1 0 0 1 1 1 1 MAPEG family MBOAT PF03062.14 EDN10887.1 - 1e-16 61.0 14.2 1.8e-16 60.1 9.5 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EDN10887.1 - 0.00099 19.1 2.5 0.0032 17.4 1.7 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF912 PF06024.7 EDN10887.1 - 0.057 13.4 0.1 0.46 10.5 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WD40 PF00400.27 EDN10888.1 - 1.1e-39 132.8 29.1 2.9e-08 33.2 1.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 EDN10888.1 - 0.0022 17.7 0.2 3.5 7.2 0.0 3.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF3517 PF12030.3 EDN10891.1 - 5e-174 577.6 0.1 8.3e-174 576.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) TFIIE_alpha PF02002.12 EDN10892.1 - 3.2e-19 68.3 0.0 1.4e-18 66.3 0.0 2.0 2 0 0 2 2 2 1 TFIIE alpha subunit Zn-ribbon_8 PF09723.5 EDN10892.1 - 0.00091 19.1 0.3 0.0018 18.1 0.2 1.5 1 0 0 1 1 1 1 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 EDN10892.1 - 0.048 12.9 0.6 0.25 10.6 0.0 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 EDN10892.1 - 0.67 9.8 3.1 2.7 7.8 2.1 2.0 1 1 2 3 3 3 0 Transposase zinc-ribbon domain PseudoU_synth_1 PF01416.15 EDN10893.1 - 3.9e-20 72.2 0.6 3.3e-09 37.0 0.0 3.1 3 0 0 3 3 3 2 tRNA pseudouridine synthase Anillin PF08174.6 EDN10894.1 - 1e-32 113.1 0.6 2.4e-32 111.9 0.4 1.7 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EDN10894.1 - 5.3e-10 39.4 0.1 2e-09 37.5 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EDN10894.1 - 0.036 14.3 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Herpes_LMP1 PF05297.6 EDN10895.1 - 3.6 6.4 7.8 5.6 5.7 0.5 2.3 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DEAD PF00270.24 EDN10896.1 - 6.2e-32 110.4 0.1 1e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDN10896.1 - 1.3e-17 63.3 0.0 2.9e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDN10896.1 - 0.00047 19.0 0.0 0.00078 18.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EDN10896.1 - 0.0015 18.3 0.0 0.0035 17.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDN10896.1 - 0.078 13.1 0.4 2.1 8.5 0.3 2.4 1 1 0 1 1 1 0 AAA domain SET PF00856.23 EDN10897.1 - 1.7e-09 38.1 0.0 3.6e-09 37.1 0.0 1.5 2 0 0 2 2 2 1 SET domain Ribosomal_L14 PF00238.14 EDN10898.1 - 1.3e-42 144.4 0.6 1.4e-42 144.2 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TFIIS_C PF01096.13 EDN10899.1 - 2.4e-15 55.8 3.1 2.4e-15 55.8 2.1 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EDN10899.1 - 8e-11 41.4 1.4 8e-11 41.4 1.0 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 EDN10899.1 - 0.026 14.7 3.6 0.026 14.7 2.5 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar Ogr_Delta PF04606.7 EDN10899.1 - 0.032 13.8 2.4 0.032 13.8 1.7 2.4 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger RecQ5 PF06959.6 EDN10899.1 - 0.056 13.0 0.8 0.057 13.0 0.5 1.1 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) C1_4 PF07975.7 EDN10899.1 - 0.17 11.9 11.0 0.22 11.5 0.6 2.5 2 1 0 2 2 2 0 TFIIH C1-like domain DZR PF12773.2 EDN10899.1 - 0.61 9.9 15.0 0.17 11.7 4.9 2.6 1 1 1 2 2 2 0 Double zinc ribbon GFA PF04828.9 EDN10899.1 - 2.2 8.2 13.5 0.064 13.2 0.7 2.8 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Cytochrome_C7 PF14522.1 EDN10899.1 - 6 6.5 9.8 22 4.7 6.8 2.0 1 1 0 1 1 1 0 Cytochrome c7 Rpr2 PF04032.11 EDN10899.1 - 6.4 6.7 12.2 1 9.2 1.5 2.7 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain OMPdecase PF00215.19 EDN10900.1 - 6e-52 176.2 0.0 7.8e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family APH PF01636.18 EDN10902.1 - 1.4e-15 57.7 0.2 3.3e-15 56.4 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN10902.1 - 5.3e-05 22.9 0.1 0.00032 20.3 0.0 2.1 1 1 0 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EDN10902.1 - 0.071 12.0 0.0 0.27 10.1 0.0 1.8 2 0 0 2 2 2 0 Fructosamine kinase DivIC PF04977.10 EDN10903.1 - 0.001 18.5 8.6 0.12 11.8 1.4 2.2 1 1 1 2 2 2 2 Septum formation initiator Spc7 PF08317.6 EDN10903.1 - 0.0053 15.4 3.6 0.0058 15.3 2.5 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3135 PF11333.3 EDN10903.1 - 0.01 15.9 1.0 0.01 15.9 0.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3135) MscS_porin PF12795.2 EDN10903.1 - 0.011 15.0 11.5 0.012 14.9 8.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Syntaxin PF00804.20 EDN10903.1 - 0.014 15.5 4.8 0.019 15.1 3.3 1.2 1 0 0 1 1 1 0 Syntaxin WEMBL PF05701.6 EDN10903.1 - 0.016 13.7 6.6 0.033 12.6 1.0 1.9 1 1 1 2 2 2 0 Weak chloroplast movement under blue light V-ATPase_G PF03179.10 EDN10903.1 - 0.018 15.3 0.8 0.018 15.3 0.6 2.0 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit FliJ PF02050.11 EDN10903.1 - 0.029 14.4 10.0 0.041 13.9 6.9 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4061 PF13270.1 EDN10903.1 - 0.063 13.3 3.4 0.19 11.8 2.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) EFG_C PF00679.19 EDN10903.1 - 0.11 12.3 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Elongation factor G C-terminus CENP-F_leu_zip PF10473.4 EDN10903.1 - 0.13 12.1 7.4 0.43 10.4 5.2 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EDN10903.1 - 0.14 11.5 5.8 0.17 11.3 4.0 1.1 1 0 0 1 1 1 0 Intermediate filament protein zf-CpG_bind_C PF12269.3 EDN10903.1 - 0.18 11.2 2.3 0.23 10.8 1.6 1.3 1 1 0 1 1 1 0 CpG binding protein zinc finger C terminal domain KxDL PF10241.4 EDN10903.1 - 0.21 11.4 3.8 0.63 9.9 2.7 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein Exonuc_VII_L PF02601.10 EDN10903.1 - 0.3 10.2 3.2 0.31 10.1 2.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GlnE PF03710.10 EDN10903.1 - 0.34 10.1 2.2 0.54 9.4 1.5 1.5 1 1 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase TBPIP PF07106.8 EDN10903.1 - 0.41 10.1 4.0 0.75 9.3 2.8 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_PEP_C PF04513.7 EDN10903.1 - 0.43 10.3 2.4 1.5 8.6 1.7 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin_2 PF01920.15 EDN10903.1 - 0.44 10.3 7.7 1.9 8.2 1.5 2.4 1 1 1 2 2 2 0 Prefoldin subunit OmpH PF03938.9 EDN10903.1 - 0.45 10.4 7.0 0.6 10.0 4.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4558 PF15104.1 EDN10903.1 - 0.46 10.4 3.9 0.6 10.0 2.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4558) Bap31 PF05529.7 EDN10903.1 - 0.47 9.8 5.9 18 4.7 0.6 2.0 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like TMF_TATA_bd PF12325.3 EDN10903.1 - 0.54 10.0 6.0 1.5 8.5 1.7 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding HSCB_C PF07743.8 EDN10903.1 - 0.79 10.2 4.9 0.33 11.4 1.0 1.8 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain V_ATPase_I PF01496.14 EDN10903.1 - 0.9 7.3 3.8 1 7.1 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EDN10903.1 - 0.96 8.3 6.0 1.1 8.1 4.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin PF02996.12 EDN10903.1 - 1.1 8.9 4.9 1.7 8.3 0.4 2.1 1 1 1 2 2 2 0 Prefoldin subunit DUF342 PF03961.8 EDN10903.1 - 1.1 7.5 3.8 1.2 7.4 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TPR_MLP1_2 PF07926.7 EDN10903.1 - 1.3 8.8 6.9 2.6 7.8 4.8 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc24 PF08286.6 EDN10903.1 - 1.5 8.5 5.0 8.3 6.1 3.3 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Cortex-I_coil PF09304.5 EDN10903.1 - 1.6 8.8 7.0 12 5.9 4.8 2.0 1 1 0 1 1 1 0 Cortexillin I, coiled coil ATP-synt_B PF00430.13 EDN10903.1 - 2.8 7.7 10.4 0.31 10.8 3.5 1.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) IncA PF04156.9 EDN10903.1 - 3 7.3 11.9 6.6 6.2 8.2 1.5 1 1 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 EDN10903.1 - 6 6.7 8.0 1e+02 2.7 5.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3886 PF13025.1 EDN10903.1 - 7.3 6.6 9.4 85 3.2 6.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3886) Herpes_U30 PF04523.8 EDN10904.1 - 0.028 11.9 3.0 0.03 11.8 2.1 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 DUF1729 PF08354.5 EDN10904.1 - 0.11 12.3 0.1 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) Adeno_E3_15_3 PF03307.9 EDN10905.1 - 0.083 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region DIPSY PF11763.3 EDN10908.1 - 0.002 17.8 0.0 0.0024 17.6 0.0 1.1 1 0 0 1 1 1 1 Cell-wall adhesin ligand-binding C-terminal DnaJ PF00226.26 EDN10911.1 - 1.2e-25 88.9 1.0 2.2e-25 88.1 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EDN10911.1 - 1.2e-15 57.3 16.1 2e-15 56.5 11.2 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EDN10911.1 - 5.3e-12 45.4 0.0 7.3e-11 41.8 0.0 2.3 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 EDN10911.1 - 0.028 14.0 8.5 0.4 10.3 1.1 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EDN10911.1 - 3.8 7.4 13.5 20 5.1 2.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon Lar_restr_allev PF14354.1 EDN10911.1 - 5.1 7.4 9.6 12 6.3 0.3 2.7 1 1 1 2 2 2 0 Restriction alleviation protein Lar Transgly PF00912.17 EDN10912.1 - 0.083 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Transglycosylase Malic_M PF03949.10 EDN10914.1 - 1e-84 284.1 0.0 1.3e-84 283.7 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EDN10914.1 - 3.4e-64 215.7 0.0 5.2e-64 215.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DBD_Tnp_Mut PF03108.10 EDN10915.1 - 2.9e-07 29.9 0.3 5.2e-07 29.1 0.2 1.4 1 0 0 1 1 1 1 MuDR family transposase Uds1 PF15456.1 EDN10915.1 - 0.013 15.4 0.5 0.024 14.6 0.3 1.3 1 0 0 1 1 1 0 Up-regulated During Septation HTH_21 PF13276.1 EDN10915.1 - 0.13 12.2 0.4 0.24 11.4 0.3 1.4 1 0 0 1 1 1 0 HTH-like domain BAF1_ABF1 PF04684.8 EDN10915.1 - 1.6 7.5 8.2 2.7 6.7 5.7 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 EDN10915.1 - 1.8 6.6 16.5 2 6.5 11.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EDN10915.1 - 2 7.7 13.6 2.9 7.1 9.4 1.2 1 0 0 1 1 1 0 Vta1 like IER PF05760.7 EDN10915.1 - 2.6 7.8 10.6 0.31 10.9 4.5 1.5 2 0 0 2 2 2 0 Immediate early response protein (IER) THOC7 PF05615.8 EDN10916.1 - 1.1e-43 148.7 9.1 1.1e-43 148.7 6.3 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 zf-C4H2 PF10146.4 EDN10916.1 - 0.0022 18.0 14.1 0.013 15.5 3.6 2.5 1 1 2 3 3 3 2 Zinc finger-containing protein CCDC92 PF14916.1 EDN10916.1 - 0.0071 15.9 0.4 0.02 14.4 0.3 1.7 1 0 0 1 1 1 1 Coiled-coil domain of unknown function SSFA2_C PF14723.1 EDN10916.1 - 0.044 13.5 3.6 0.093 12.4 2.5 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus CDC37_N PF03234.9 EDN10916.1 - 0.61 10.3 7.2 1.2 9.4 5.0 1.4 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding FUSC PF04632.7 EDN10916.1 - 1.2 7.5 6.5 1.4 7.2 4.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.4 EDN10916.1 - 1.3 7.8 7.1 1.9 7.3 5.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF812 PF05667.6 EDN10916.1 - 2.5 6.4 16.8 5.9 5.2 11.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF972 PF06156.8 EDN10916.1 - 5.7 7.3 8.7 1.4 9.2 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Ank PF00023.25 EDN10917.1 - 3.6e-08 32.8 0.0 0.036 13.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EDN10917.1 - 1.4e-07 31.8 0.0 0.0019 18.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDN10917.1 - 2e-07 31.2 0.0 5.9e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDN10917.1 - 1e-06 28.7 0.0 0.00013 22.1 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN10917.1 - 1.2e-06 28.1 0.0 0.074 13.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat DUF3723 PF12520.3 EDN10919.1 - 8.7e-105 351.1 0.0 1e-104 350.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) NAD_binding_6 PF08030.7 EDN10920.1 - 6.5e-08 32.6 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EDN10920.1 - 1.2e-07 31.4 0.0 2.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EDN10920.1 - 4 7.5 16.0 2.3 8.3 4.4 2.4 1 1 1 2 2 2 0 Ferric reductase like transmembrane component RVT_1 PF00078.22 EDN10923.1 - 1.4e-30 106.2 0.0 3.1e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN10923.1 - 2.2e-21 75.6 0.3 1e-20 73.5 0.1 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN10923.1 - 3e-16 59.9 1.5 4.9e-16 59.2 0.1 2.2 2 0 0 2 2 2 1 RNase H Exo_endo_phos PF03372.18 EDN10923.1 - 1.8e-06 28.0 0.4 4.3e-06 26.8 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ATG16 PF08614.6 EDN10923.1 - 0.0008 19.2 1.9 0.0023 17.7 1.3 1.8 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) HALZ PF02183.13 EDN10923.1 - 0.001 18.6 3.4 0.001 18.6 2.3 1.9 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF972 PF06156.8 EDN10923.1 - 0.019 15.3 0.4 0.073 13.4 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF2841 PF11001.3 EDN10924.1 - 3.7e-50 169.0 0.5 5.5e-50 168.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF382 PF04037.8 EDN10925.1 - 0.011 15.6 0.1 0.026 14.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF382) TBCA PF02970.11 EDN10929.1 - 1.6e-14 53.7 1.5 1.8e-14 53.5 1.0 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A T2SM PF04612.7 EDN10929.1 - 0.04 13.7 0.8 0.04 13.7 0.6 1.2 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M APG6 PF04111.7 EDN10929.1 - 0.15 11.0 2.1 0.17 10.9 1.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 FadA PF09403.5 EDN10929.1 - 0.17 11.9 2.0 0.19 11.7 1.4 1.1 1 0 0 1 1 1 0 Adhesion protein FadA MFS_1 PF07690.11 EDN10930.1 - 2.5e-16 59.3 24.5 2.5e-16 59.3 17.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Band_7 PF01145.20 EDN10931.1 - 3.3e-16 59.6 0.0 3.3e-16 59.6 0.0 3.0 2 1 1 3 3 3 1 SPFH domain / Band 7 family Hemerythrin PF01814.18 EDN10932.1 - 5.9e-11 42.6 2.5 9.7e-11 41.9 1.7 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DnaI_N PF07319.6 EDN10932.1 - 0.031 14.5 0.2 0.28 11.4 0.0 2.2 1 1 1 3 3 3 0 Primosomal protein DnaI N-terminus L_protein_N PF15518.1 EDN10932.1 - 0.034 13.5 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 L protein N-terminus DUF4621 PF15414.1 EDN10932.1 - 0.13 10.9 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4621) Sugar_tr PF00083.19 EDN10934.1 - 6.8e-60 202.9 26.8 2.7e-59 200.9 18.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EDN10934.1 - 0.00019 19.9 28.2 0.00046 18.6 4.2 3.7 2 2 2 4 4 4 3 MFS/sugar transport protein MFS_1 PF07690.11 EDN10934.1 - 0.0014 17.4 39.0 0.0021 16.8 23.2 3.2 1 1 2 3 3 3 2 Major Facilitator Superfamily Elongin_A PF06881.6 EDN10935.1 - 1.3e-16 60.8 0.1 2.5e-16 60.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Ribosomal_L44 PF00935.14 EDN10936.1 - 4e-35 119.6 11.7 7.3e-35 118.8 8.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 Macoilin PF09726.4 EDN10936.1 - 0.033 12.4 1.4 0.04 12.2 1.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Vac7 PF12751.2 EDN10937.1 - 2e-186 619.5 2.4 2.7e-186 619.0 1.7 1.2 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 DUF3824 PF12868.2 EDN10938.1 - 1.9e-53 181.0 33.6 1.9e-53 181.0 23.3 9.1 4 1 7 11 11 11 2 Domain of unknwon function (DUF3824) DUF2613 PF11021.3 EDN10938.1 - 0.028 14.1 0.1 0.22 11.2 0.1 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) CbtA PF09490.5 EDN10938.1 - 0.24 10.6 0.3 0.65 9.2 0.1 1.9 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) DUF3042 PF11240.3 EDN10938.1 - 1.4 8.7 5.8 0.31 10.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) CorA PF01544.13 EDN10939.1 - 4.5e-22 78.4 0.0 6.8e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein rve PF00665.21 EDN10942.1 - 9e-17 61.3 0.0 1.9e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EDN10942.1 - 2.1e-15 56.0 2.8 5.6e-15 54.7 2.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EDN10942.1 - 0.0022 17.3 0.1 0.0052 16.1 0.0 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Lipase_GDSL_2 PF13472.1 EDN10943.1 - 9.1e-11 42.2 0.4 1.2e-10 41.7 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EDN10943.1 - 0.0001 22.2 0.0 0.00018 21.4 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EDN10943.1 - 0.00023 20.9 0.0 0.00029 20.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF4034 PF13226.1 EDN10944.1 - 0.11 11.5 0.1 0.28 10.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4034) Zn_clus PF00172.13 EDN10945.1 - 3.9e-12 45.8 12.2 6.6e-12 45.1 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4071 PF13281.1 EDN10945.1 - 0.027 13.3 0.5 0.036 12.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) RRN7 PF11781.3 EDN10945.1 - 0.068 12.6 5.5 0.14 11.7 3.8 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Ribosomal_L19e PF01280.15 EDN10947.1 - 1e-34 119.4 0.3 2.5e-34 118.2 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT_2 PF13646.1 EDN10947.1 - 2.5e-29 101.3 44.8 4e-09 36.6 0.0 13.0 6 4 6 12 12 12 7 HEAT repeats HEAT PF02985.17 EDN10947.1 - 1.9e-27 92.8 31.5 0.052 13.6 0.0 18.0 21 0 0 21 21 19 8 HEAT repeat DUF3554 PF12074.3 EDN10947.1 - 2.5e-26 92.9 3.4 3.9e-17 62.7 0.0 5.5 4 1 1 5 5 5 2 Domain of unknown function (DUF3554) HEAT_EZ PF13513.1 EDN10947.1 - 2.5e-24 85.0 51.8 2.3e-05 24.7 0.0 19.9 14 3 8 22 22 22 8 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EDN10947.1 - 5.7e-11 42.6 0.3 0.072 13.4 0.1 7.1 7 2 1 8 8 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EDN10947.1 - 3.1e-10 40.1 0.0 0.7 9.7 0.0 7.7 7 2 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EDN10947.1 - 2e-08 33.8 0.0 2.5 7.4 0.0 6.3 4 2 2 6 6 6 1 CLASP N terminal ParcG PF10274.4 EDN10947.1 - 2e-07 31.0 1.5 0.39 10.5 0.0 5.7 6 1 1 7 7 7 2 Parkin co-regulated protein Ipi1_N PF12333.3 EDN10947.1 - 3.1e-06 27.1 0.2 4.1 7.4 0.1 6.2 5 0 0 5 5 5 2 Rix1 complex component involved in 60S ribosome maturation DUF3535 PF12054.3 EDN10947.1 - 0.022 13.3 0.7 0.067 11.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3535) GSHPx PF00255.14 EDN10947.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione peroxidase HA2 PF04408.18 EDN10948.1 - 9.7e-19 67.2 0.0 2.6e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDN10948.1 - 8.4e-13 47.9 0.1 2e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN10948.1 - 1.2e-09 37.9 0.0 2.9e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDN10948.1 - 3.1e-06 27.3 0.1 1.3e-05 25.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvA_C PF07499.8 EDN10948.1 - 0.88 9.7 3.9 1.2 9.4 0.1 2.9 3 0 0 3 3 3 0 RuvA, C-terminal domain BRCT PF00533.21 EDN10949.1 - 0.0003 20.8 0.0 0.00065 19.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EDN10949.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain KilA-N PF04383.8 EDN10952.1 - 0.0032 17.0 0.0 0.007 15.9 0.0 1.6 1 0 0 1 1 1 1 KilA-N domain Mg_trans_NIPA PF05653.9 EDN10953.1 - 1.7e-86 289.8 24.6 2.5e-86 289.3 17.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EDN10953.1 - 7.9e-06 26.0 8.8 7.9e-06 26.0 6.1 3.7 2 1 2 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 EDN10953.1 - 4.9e-05 23.3 7.2 4.9e-05 23.3 5.0 2.9 2 1 0 2 2 2 1 EamA-like transporter family Patatin PF01734.17 EDN10954.1 - 8.9e-28 97.6 0.0 1.3e-27 97.0 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase MOSC PF03473.12 EDN10956.1 - 0.00078 18.9 0.0 0.0045 16.4 0.0 2.0 1 1 1 2 2 2 1 MOSC domain SHMT PF00464.14 EDN10957.1 - 5.4e-198 657.2 0.0 6.3e-198 657.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase AMP-binding PF00501.23 EDN10958.1 - 8.6e-69 231.9 0.0 1.1e-68 231.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Ras PF00071.17 EDN10959.1 - 4.7e-32 110.6 0.1 1.9e-31 108.6 0.1 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EDN10959.1 - 2.2e-07 31.3 0.0 6.7e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Miro-like protein FeoB_N PF02421.13 EDN10959.1 - 0.075 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B GST_N_2 PF13409.1 EDN10960.1 - 4.9e-21 74.5 0.0 1e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDN10960.1 - 6.3e-16 58.0 0.0 8e-15 54.4 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EDN10960.1 - 8.7e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDN10960.1 - 0.00021 21.6 0.1 0.00047 20.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EDN10960.1 - 0.00022 21.3 0.0 0.0054 16.9 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TPR_MLP1_2 PF07926.7 EDN10962.1 - 0.019 14.7 20.6 0.23 11.1 6.5 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF641 PF04859.7 EDN10962.1 - 0.021 14.5 0.9 0.021 14.5 0.6 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) WEMBL PF05701.6 EDN10962.1 - 0.024 13.1 18.3 0.034 12.6 12.7 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light SlyX PF04102.7 EDN10962.1 - 0.027 14.8 1.9 0.027 14.8 1.3 2.5 1 1 1 2 2 2 0 SlyX IncA PF04156.9 EDN10962.1 - 0.075 12.6 13.9 0.14 11.7 9.6 1.4 1 0 0 1 1 1 0 IncA protein DUF2968 PF11180.3 EDN10962.1 - 0.28 10.5 11.5 1.3 8.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Fez1 PF06818.10 EDN10962.1 - 0.38 10.7 16.0 0.66 9.9 11.1 1.3 1 0 0 1 1 1 0 Fez1 DUF4407 PF14362.1 EDN10962.1 - 0.46 9.3 5.5 0.72 8.7 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.3 EDN10962.1 - 0.69 7.1 14.0 0.91 6.7 9.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.4 EDN10962.1 - 1.2 8.9 20.7 1.4 8.8 13.4 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 EDN10962.1 - 3.6 7.3 20.3 6.7 6.4 5.6 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.1 EDN10962.1 - 4.2 6.5 18.8 13 4.9 13.0 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 EDN10962.1 - 4.4 6.1 18.4 65 2.3 12.8 2.0 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 EDN10962.1 - 5.1 7.2 6.9 2 8.5 1.1 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 EDN10962.1 - 8.1 6.3 17.0 2.1 8.1 5.4 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EDN10962.1 - 8.4 6.2 18.5 29 4.5 12.8 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding ERM PF00769.14 EDN10962.1 - 8.9 5.7 22.5 5.7 6.3 7.0 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.2 EDN10962.1 - 9.4 6.0 25.2 1.3e+03 -0.9 17.5 2.8 1 1 0 1 1 1 0 Tropomyosin like Mcp5_PH PF12814.2 EDN10963.1 - 2.2e-48 163.2 0.1 3.4e-48 162.6 0.1 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology CAF1A PF12253.3 EDN10963.1 - 0.067 13.3 0.2 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Cyt-b5 PF00173.23 EDN10964.1 - 1.1e-18 66.8 0.1 1.2e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EFP_N PF08207.7 EDN10964.1 - 0.077 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain BRX PF08381.6 EDN10964.1 - 0.087 11.8 0.3 0.81 8.7 0.2 2.5 1 1 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 Helicase_C PF00271.26 EDN10965.1 - 4.8e-12 45.5 0.0 1.2e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDN10965.1 - 1.9e-05 24.2 0.1 3.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EDN10965.1 - 3.4e-05 22.9 0.0 7.1e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EDN10965.1 - 7e-05 22.9 0.0 0.00023 21.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain PWI PF01480.12 EDN10965.1 - 0.00085 19.3 0.0 0.0023 18.0 0.0 1.8 1 0 0 1 1 1 1 PWI domain SRP54 PF00448.17 EDN10965.1 - 0.0029 17.0 0.3 0.0075 15.7 0.2 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.1 EDN10965.1 - 0.011 15.8 0.0 0.038 14.0 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 EDN10965.1 - 0.02 14.6 0.4 0.16 11.7 0.1 2.6 3 0 0 3 3 3 0 Part of AAA domain AAA_23 PF13476.1 EDN10965.1 - 0.061 13.6 0.1 0.061 13.6 0.1 3.5 1 1 1 2 2 1 0 AAA domain AAA_29 PF13555.1 EDN10965.1 - 0.099 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EDN10965.1 - 1.3 9.3 6.4 0.21 11.8 0.1 2.7 1 1 1 2 2 2 0 ABC transporter Pkinase PF00069.20 EDN10966.1 - 8e-30 103.8 0.0 2.6e-29 102.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN10966.1 - 1.7e-17 63.3 0.0 3.2e-17 62.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EDN10966.1 - 0.011 15.5 0.1 0.018 14.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2748 PF10871.3 EDN10966.1 - 0.22 9.9 0.0 0.31 9.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) AMP-binding PF00501.23 EDN10967.1 - 5e-90 301.8 0.0 7.2e-90 301.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EDN10967.1 - 1.9e-30 105.7 0.0 2.7e-12 46.1 0.0 3.9 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.20 EDN10967.1 - 2.5e-20 72.5 2.6 3.4e-09 36.8 0.4 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EDN10967.1 - 0.0014 18.8 0.2 1.3 9.3 0.0 3.1 2 0 0 2 2 2 2 HxxPF-repeated domain Imm1 PF14430.1 EDN10967.1 - 0.023 14.8 0.0 0.065 13.3 0.0 1.8 1 0 0 1 1 1 0 Immunity protein Imm1 AMP-binding_C PF13193.1 EDN10967.1 - 0.081 13.8 0.0 0.2 12.6 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EDN10968.1 - 2.4e-59 200.7 0.0 3.6e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EDN10968.1 - 3.6e-06 27.1 0.1 7.8e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.15 EDN10968.1 - 9.4e-05 21.4 0.2 0.00014 20.8 0.1 1.3 1 0 0 1 1 1 1 Condensation domain Ank_2 PF12796.2 EDN10969.1 - 2.1e-29 101.7 0.0 1.8e-12 47.4 0.1 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EDN10969.1 - 2.5e-26 90.0 5.6 5.1e-05 22.8 0.0 6.9 6 1 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EDN10969.1 - 7.6e-22 76.8 1.1 1.3e-08 34.8 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDN10969.1 - 1.9e-21 75.9 0.2 1.1e-05 25.8 0.4 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN10969.1 - 6.7e-18 63.0 2.1 0.039 14.2 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Cyclin PF08613.6 EDN10969.1 - 2.7e-15 57.0 0.0 5.8e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin zf-DHHC PF01529.15 EDN10969.1 - 0.063 12.6 10.7 0.2 11.0 7.4 1.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase Methyltransf_24 PF13578.1 EDN10970.1 - 0.078 13.8 0.3 15 6.5 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain DUF1910 PF08928.5 EDN10970.1 - 0.16 12.0 5.1 0.61 10.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) CorA PF01544.13 EDN10970.1 - 1.3 7.9 11.4 0.15 11.0 3.5 2.5 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Snf7 PF03357.16 EDN10970.1 - 6.3 6.1 21.1 0.15 11.4 5.2 3.2 2 1 1 3 3 3 0 Snf7 Na_Ca_ex PF01699.19 EDN10971.1 - 2.7e-17 62.6 23.0 1.1e-09 38.0 5.1 2.7 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF3169 PF11368.3 EDN10971.1 - 0.043 13.0 0.0 0.043 13.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF2633 PF11119.3 EDN10971.1 - 0.11 12.1 1.4 0.32 10.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) DUF4131 PF13567.1 EDN10971.1 - 1.3 8.4 7.3 13 5.1 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF202 PF02656.10 EDN10971.1 - 1.6 9.0 11.1 6.4 7.0 0.2 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF202) DUF872 PF05915.7 EDN10971.1 - 2 8.2 7.4 0.33 10.8 0.1 2.8 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) N_methyl_2 PF13544.1 EDN10971.1 - 2.1 7.9 0.0 2.1 7.9 0.0 3.9 4 0 0 4 4 4 0 Type IV pilin N-term methylation site GFxxxE DUF4014 PF13198.1 EDN10971.1 - 4.9 7.6 6.6 7.8 6.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4014) DUF3357 PF11837.3 EDN10971.1 - 7.6 6.4 8.8 4.9 7.0 0.0 3.6 4 1 1 5 5 5 0 Domain of unknown function (DUF3357) PrgI PF12666.2 EDN10971.1 - 9.7 6.4 11.7 2.8 8.1 0.5 4.1 4 1 1 5 5 5 0 PrgI family protein Abhydrolase_6 PF12697.2 EDN10972.1 - 1.8e-26 93.4 0.0 2.2e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDN10972.1 - 6.6e-10 38.9 0.0 1.4e-09 37.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDN10972.1 - 3.4e-08 33.3 0.0 1.4e-06 28.0 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EDN10972.1 - 0.00022 20.9 0.0 0.0054 16.5 0.0 2.7 2 1 0 2 2 2 1 Putative lysophospholipase PALP PF00291.20 EDN10973.1 - 1.4e-59 201.7 0.1 2.1e-59 201.2 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EDN10973.1 - 3.5e-07 29.9 0.0 1.1e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 CBS domain AA_kinase PF00696.23 EDN10974.1 - 1.6e-30 106.4 0.3 2.3e-30 105.9 0.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EDN10974.1 - 3.3e-16 58.7 0.1 5.8e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 PUA domain Peptidase_M76 PF09768.4 EDN10975.1 - 1.1e-46 158.5 3.8 1.2e-46 158.3 2.6 1.0 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M13 PF01431.16 EDN10975.1 - 0.038 13.1 0.8 0.042 13.0 0.6 1.2 1 1 0 1 1 1 0 Peptidase family M13 Pkinase PF00069.20 EDN10976.1 - 1.5e-70 237.3 0.0 1.9e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN10976.1 - 1.5e-43 148.7 0.0 2e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDN10976.1 - 6.6e-07 28.5 0.0 5e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EDN10976.1 - 0.00016 20.8 0.1 0.00026 20.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EDN10976.1 - 0.0042 16.4 0.0 0.0078 15.5 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EDN10976.1 - 0.05 13.3 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family TIP41 PF04176.8 EDN10977.1 - 4.2e-15 55.4 0.0 5.8e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family Ubiq_cyt_C_chap PF03981.7 EDN10978.1 - 3.1e-41 140.5 0.0 4e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Peptidase_M1 PF01433.15 EDN10979.1 - 1.4e-77 261.4 0.0 1.8e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EDN10979.1 - 2.1e-28 98.6 0.1 1.3e-27 96.1 0.0 2.1 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EDN10979.1 - 2.5e-18 66.3 0.1 4.1e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EDN10979.1 - 0.086 12.8 2.4 0.42 10.5 1.6 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase RVT_1 PF00078.22 EDN10981.1 - 1.6e-35 122.4 0.0 2.5e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN10981.1 - 5.3e-15 55.9 0.0 1.3e-14 54.6 0.0 1.7 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN10981.1 - 2.1e-13 49.8 0.0 4.6e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase BTB PF00651.26 EDN10983.1 - 7.9e-05 22.6 0.0 0.0003 20.7 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain AhpC-TSA PF00578.16 EDN10984.1 - 2.2e-23 82.3 0.0 3.6e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EDN10984.1 - 2.3e-15 56.4 0.0 3.6e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EDN10984.1 - 9e-05 22.3 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Peptidase_M74 PF03411.8 EDN10984.1 - 0.27 10.4 2.1 0.46 9.6 1.5 1.3 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase DUF3435 PF11917.3 EDN10985.1 - 1.5e-155 518.0 0.0 2.1e-155 517.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) GCOM2 PF15328.1 EDN10985.1 - 0.058 13.1 2.0 0.13 11.9 1.4 1.5 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Apelin PF15360.1 EDN10986.1 - 0.036 14.2 1.1 0.056 13.6 0.2 1.7 2 0 0 2 2 2 0 APJ endogenous ligand RVT_1 PF00078.22 EDN10987.1 - 4.1e-30 104.7 0.0 9.5e-30 103.5 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN10987.1 - 2.6e-18 65.7 0.8 8.4e-18 64.1 0.1 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EDN10987.1 - 2.4e-17 63.5 0.0 6.9e-17 62.0 0.0 1.9 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN10987.1 - 6.2e-06 25.9 0.0 2e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase-like zf-CCHC PF00098.18 EDN10987.1 - 0.0078 16.0 4.2 0.025 14.4 2.9 2.0 1 0 0 1 1 1 1 Zinc knuckle RVT_2 PF07727.9 EDN10988.1 - 2e-50 171.0 0.0 8.5e-50 169.0 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN10988.1 - 2e-15 56.9 0.0 5.1e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN10988.1 - 0.0022 17.6 0.0 0.005 16.4 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF1795 PF08786.6 EDN10989.1 - 0.06 13.1 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1795) AAA PF00004.24 EDN10990.1 - 1.2e-17 64.3 0.0 2.5e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN10990.1 - 0.00018 21.5 0.0 0.0053 16.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EDN10990.1 - 0.00028 21.1 1.0 0.24 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EDN10990.1 - 0.00051 20.8 2.3 0.0018 19.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDN10990.1 - 0.0015 18.2 0.0 0.0039 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDN10990.1 - 0.0044 17.1 0.1 0.078 13.1 0.0 2.8 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EDN10990.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.7 EDN10990.1 - 0.03 13.3 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EDN10990.1 - 0.034 13.7 0.0 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDN10990.1 - 0.12 12.5 0.0 0.41 10.8 0.0 2.0 1 0 0 1 1 1 0 RNA helicase HEAT_2 PF13646.1 EDN10994.1 - 5.5e-57 190.0 19.1 2.4e-17 63.0 0.2 4.8 1 1 3 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 EDN10994.1 - 7.9e-39 131.2 17.4 0.001 19.5 0.1 8.6 9 0 0 9 9 8 8 HEAT-like repeat HEAT PF02985.17 EDN10994.1 - 1.1e-36 121.5 0.5 0.00075 19.3 0.0 9.1 9 0 0 9 9 9 8 HEAT repeat Arm PF00514.18 EDN10994.1 - 9.3e-24 82.3 4.6 0.017 14.9 0.0 9.0 8 1 1 9 9 9 5 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 EDN10994.1 - 8.5e-23 78.4 8.3 0.11 13.0 0.0 8.6 8 0 0 8 8 8 6 PBS lyase HEAT-like repeat Adaptin_N PF01602.15 EDN10994.1 - 1e-14 53.7 0.7 0.0002 19.8 0.1 3.4 1 1 2 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.2 EDN10994.1 - 1.9e-11 44.1 0.6 1.3 8.8 0.0 8.0 1 1 6 7 7 7 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EDN10994.1 - 2.9e-09 36.6 1.8 0.025 13.9 0.0 4.6 2 1 2 4 4 4 2 CLASP N terminal DUF3944 PF13099.1 EDN10994.1 - 7.7e-08 31.6 18.4 0.17 11.4 0.2 8.2 8 0 0 8 8 8 2 Domain of unknown function (DUF3944) DUF1087 PF06465.8 EDN10994.1 - 1.6e-07 31.1 6.2 0.31 11.0 0.0 6.1 8 0 0 8 8 7 2 Domain of Unknown Function (DUF1087) Vac14_Fab1_bd PF12755.2 EDN10994.1 - 3.7e-05 24.0 0.7 16 5.9 0.1 5.6 3 2 2 5 5 5 0 Vacuolar 14 Fab1-binding region Aconitase_B_N PF11791.3 EDN10994.1 - 0.00035 20.4 8.0 6 6.6 0.0 5.8 1 1 5 6 6 6 0 Aconitate B N-terminal domain CHASE2 PF05226.6 EDN10994.1 - 0.00085 18.6 5.4 1.2 8.2 3.8 2.9 1 1 0 1 1 1 1 CHASE2 domain Nipped-B_C PF12830.2 EDN10994.1 - 0.0012 18.4 0.5 4.7 6.8 0.0 4.7 1 1 2 3 3 3 1 Sister chromatid cohesion C-terminus TFCD_C PF12612.3 EDN10994.1 - 0.0013 18.1 9.0 0.13 11.6 0.5 4.5 1 1 2 4 4 4 1 Tubulin folding cofactor D C terminal DUF2622 PF11080.3 EDN10994.1 - 0.0037 17.0 1.1 8.8 6.2 0.0 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF2622) DUF4439 PF14530.1 EDN10994.1 - 0.0088 16.5 4.6 20 5.6 0.1 4.9 1 1 4 6 6 6 0 Domain of unknown function (DUF4439) Tol_Tol_Ttg2 PF05494.7 EDN10994.1 - 0.021 14.3 0.2 3.3 7.2 0.0 3.4 2 1 3 5 5 5 0 Toluene tolerance, Ttg2 KH_4 PF13083.1 EDN10994.1 - 0.1 12.2 4.0 96 2.7 0.0 5.3 6 0 0 6 6 5 0 KH domain DUF520 PF04461.8 EDN10994.1 - 0.1 12.4 5.9 15 5.4 0.2 3.8 1 1 4 5 5 5 0 Protein of unknown function (DUF520) DED PF01335.16 EDN10994.1 - 0.67 10.1 16.7 16 5.6 0.5 5.5 2 2 5 7 7 7 0 Death effector domain V-ATPase_H_N PF03224.9 EDN10994.1 - 1.1 8.3 9.0 45 3.0 6.2 2.7 1 1 0 1 1 1 0 V-ATPase subunit H Mo25 PF08569.6 EDN10994.1 - 1.9 7.4 4.3 18 4.2 0.2 2.4 1 1 2 3 3 3 0 Mo25-like PUL PF08324.6 EDN10994.1 - 2.7 6.7 20.1 7.5 5.2 0.9 5.6 1 1 5 6 6 6 0 PUL domain PC_rep PF01851.17 EDN10994.1 - 2.8 8.3 11.6 45 4.5 0.0 5.8 6 0 0 6 6 6 0 Proteasome/cyclosome repeat Merozoite_SPAM PF07133.6 EDN10994.1 - 3.1 7.6 9.1 18 5.1 0.3 4.5 3 2 1 4 4 4 0 Merozoite surface protein (SPAM) NACHT PF05729.7 EDN10995.1 - 1e-11 44.7 0.0 2.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EDN10995.1 - 8.6e-07 28.0 0.0 1.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EDN10995.1 - 8.8e-05 22.6 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN10995.1 - 0.0016 19.2 0.0 0.004 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDN10995.1 - 0.0023 18.2 0.0 0.0096 16.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain PNP_UDP_1 PF01048.15 EDN10995.1 - 0.0027 16.6 0.0 0.0043 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily NTPase_1 PF03266.10 EDN10995.1 - 0.0052 16.5 0.0 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 NTPase AAA_14 PF13173.1 EDN10995.1 - 0.0068 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN10995.1 - 0.036 14.0 0.0 0.17 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EDN10995.1 - 0.039 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EDN10995.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EDN10995.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 EDN10995.1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EDN10995.1 - 0.086 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EDN10995.1 - 0.12 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Viral_helicase1 PF01443.13 EDN10995.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RVT_1 PF00078.22 EDN10997.1 - 1e-31 109.9 0.0 2.1e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN10997.1 - 1e-14 55.0 0.0 2.7e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN10997.1 - 4.2e-11 42.4 0.0 9.8e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase CI-B14_5a PF07347.7 EDN10998.1 - 0.027 14.2 0.0 0.082 12.6 0.0 1.8 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DDHD PF02862.12 EDN10999.1 - 1e-36 126.8 0.0 1e-36 126.8 0.0 1.8 2 0 0 2 2 2 1 DDHD domain CH PF00307.26 EDN11000.1 - 2e-59 198.3 0.0 4.8e-19 68.3 0.4 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EDN11000.1 - 1.5e-06 28.2 0.4 4.2e-05 23.5 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 EDN11000.1 - 0.00017 21.1 0.0 0.86 9.2 0.0 3.6 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_1 PF00036.27 EDN11000.1 - 0.01 15.0 0.7 0.92 8.9 0.1 3.1 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.1 EDN11000.1 - 0.028 14.3 2.6 0.26 11.2 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain Mito_carr PF00153.22 EDN11001.1 - 5.8e-78 256.7 1.7 1.6e-26 91.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L18e PF00828.14 EDN11002.1 - 5.6e-26 91.4 0.1 8.7e-26 90.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Aldedh PF00171.17 EDN11003.1 - 1.5e-10 40.0 0.5 4e-07 28.7 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family DUF1649 PF07855.7 EDN11003.1 - 0.072 12.7 0.2 9.9 5.8 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1649) AA_permease PF00324.16 EDN11004.1 - 0.00013 20.4 0.4 0.00019 19.9 0.3 1.1 1 0 0 1 1 1 1 Amino acid permease Cu_amine_oxid PF01179.15 EDN11005.1 - 9e-164 545.0 0.0 1.1e-163 544.7 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EDN11005.1 - 0.01 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain YqzE PF14038.1 EDN11006.1 - 5.8 6.7 6.7 52 3.6 0.0 2.6 2 1 0 2 2 2 0 YqzE-like protein DUF3269 PF11673.3 EDN11009.1 - 0.038 14.4 2.0 0.046 14.1 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3269) Barstar PF01337.13 EDN11009.1 - 0.13 12.0 0.5 0.18 11.6 0.3 1.4 1 1 0 1 1 1 0 Barstar (barnase inhibitor) Pkinase PF00069.20 EDN11012.1 - 0.00053 19.2 0.0 0.00063 18.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RRM_1 PF00076.17 EDN11013.1 - 1.5e-15 56.5 0.0 2.4e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN11013.1 - 6.4e-10 38.8 0.0 4.4e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDN11013.1 - 0.011 15.6 0.0 5.1 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RVT_2 PF07727.9 EDN11014.1 - 5.9e-31 107.3 0.1 9.3e-31 106.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN11014.1 - 1.8e-16 60.3 0.0 3.8e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN11014.1 - 4.7e-08 32.5 0.0 1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 EDN11014.1 - 0.15 11.5 0.0 0.37 10.3 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain RVT_2 PF07727.9 EDN11015.1 - 6e-72 241.5 0.0 7.8e-72 241.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EDN11017.1 - 3e-20 72.5 0.0 4.6e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAM PF02365.10 EDN11020.1 - 0.015 15.5 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 No apical meristem (NAM) protein PBP1_TM PF14812.1 EDN11020.1 - 6.7 7.0 10.0 33 4.8 0.0 4.9 5 1 1 6 6 6 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3505 PF12013.3 EDN11021.1 - 1.3e-18 67.2 2.5 1.3e-18 67.2 1.8 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3505) Trypan_PARP PF05887.6 EDN11021.1 - 1.3 8.8 4.9 2.3 8.0 3.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Borrelia_P83 PF05262.6 EDN11021.1 - 2.1 6.5 10.0 4.2 5.5 1.7 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein Helicase_C PF00271.26 EDN11024.1 - 2e-12 46.7 0.0 5.2e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RVT_1 PF00078.22 EDN11026.1 - 1.3e-21 76.9 0.1 3e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN11026.1 - 1.1e-17 64.2 0.4 3.4e-17 62.6 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 EDN11026.1 - 3.6e-13 48.9 1.0 8.4e-13 47.7 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EDN11026.1 - 0.00015 21.0 0.1 0.00045 19.5 0.0 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Tudor-knot PF11717.3 EDN11026.1 - 0.0031 17.1 0.4 0.028 14.1 0.0 2.6 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain RVP PF00077.15 EDN11026.1 - 0.028 14.3 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EDN11026.1 - 0.07 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EDN11026.1 - 0.15 12.6 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease GRIP PF01465.15 EDN11027.1 - 1.8e-18 65.7 0.1 3.5e-18 64.8 0.1 1.5 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.6 EDN11027.1 - 0.00024 19.9 84.6 0.0092 14.6 6.1 5.6 2 1 3 5 5 5 5 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EDN11027.1 - 0.0003 20.0 29.0 0.16 11.0 0.8 5.4 3 1 1 5 5 5 3 Reovirus sigma C capsid protein DUF869 PF05911.6 EDN11027.1 - 0.00063 18.1 89.6 0.069 11.3 5.8 4.5 2 1 2 4 4 4 4 Plant protein of unknown function (DUF869) Baculo_PEP_C PF04513.7 EDN11027.1 - 0.0042 16.8 28.6 0.092 12.5 0.6 5.9 3 1 1 6 6 6 3 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC155 PF14662.1 EDN11027.1 - 0.0065 16.0 15.3 0.0065 16.0 10.6 6.4 3 2 2 6 6 6 1 Coiled-coil region of CCDC155 Filament PF00038.16 EDN11027.1 - 0.0091 15.5 98.2 0.1 12.0 3.6 7.3 2 2 5 7 7 7 3 Intermediate filament protein Myosin_tail_1 PF01576.14 EDN11027.1 - 0.01 13.5 107.7 0.032 11.9 38.5 4.1 2 1 2 4 4 4 0 Myosin tail AAA_13 PF13166.1 EDN11027.1 - 0.011 14.2 69.1 0.26 9.7 10.5 4.7 2 1 2 4 4 4 0 AAA domain CENP-F_leu_zip PF10473.4 EDN11027.1 - 0.024 14.4 114.1 0.022 14.5 8.6 7.5 3 3 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EDN11027.1 - 0.038 13.5 112.1 0.018 14.6 6.5 7.3 2 2 4 6 6 6 0 IncA protein APG6 PF04111.7 EDN11027.1 - 0.049 12.6 96.3 0.033 13.2 6.3 6.3 2 2 4 6 6 6 0 Autophagy protein Apg6 Snapin_Pallidin PF14712.1 EDN11027.1 - 0.072 13.4 0.3 0.072 13.4 0.2 8.0 5 4 3 8 8 8 0 Snapin/Pallidin TPR_MLP1_2 PF07926.7 EDN11027.1 - 2 8.1 94.6 0.012 15.3 5.3 8.8 2 2 4 6 6 5 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 EDN11027.1 - 8.4 5.5 96.9 0.61 9.2 5.5 7.4 3 1 2 6 6 6 0 Growth-arrest specific micro-tubule binding CAF-1_p150 PF11600.3 EDN11028.1 - 0.094 12.0 20.4 0.11 11.8 14.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Spore_III_AB PF09548.5 EDN11028.1 - 0.11 12.1 7.4 0.16 11.7 5.2 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Bestrophin PF01062.16 EDN11028.1 - 0.24 10.3 3.7 0.29 10.0 2.6 1.0 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel AAA_23 PF13476.1 EDN11028.1 - 1 9.6 11.0 1.2 9.4 7.6 1.0 1 0 0 1 1 1 0 AAA domain DUF2407_C PF13373.1 EDN11028.1 - 1.5 8.7 6.4 2.3 8.1 4.4 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain MRP-S26 PF14943.1 EDN11028.1 - 2.2 7.8 19.7 2.9 7.4 13.6 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DDHD PF02862.12 EDN11028.1 - 8 6.1 12.7 9.2 5.9 8.8 1.0 1 0 0 1 1 1 0 DDHD domain RNase_H PF00075.19 EDN11029.1 - 4.2e-15 56.2 0.0 7.5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN11029.1 - 0.063 13.0 1.5 0.33 10.7 0.0 2.9 3 1 0 3 3 3 0 Reverse transcriptase-like FlxA PF14282.1 EDN11030.1 - 0.01 15.7 3.5 0.13 12.1 2.5 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF1409 PF07197.7 EDN11030.1 - 3.1 7.9 6.1 5.3 7.1 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1409) GrpE PF01025.14 EDN11030.1 - 7.7 6.0 9.6 3.8e+02 0.5 6.7 2.1 1 1 0 1 1 1 0 GrpE rve PF00665.21 EDN11031.1 - 8.2e-05 22.6 0.2 0.00081 19.4 0.0 2.6 3 0 0 3 3 3 1 Integrase core domain zf-H2C2 PF09337.5 EDN11031.1 - 0.0027 17.0 0.1 0.0057 16.0 0.0 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_thumb PF06817.9 EDN11031.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase thumb domain DUF1729 PF08354.5 EDN11032.1 - 0.026 14.2 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) RVT_1 PF00078.22 EDN11034.1 - 1.6e-24 86.4 0.0 3.4e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN11034.1 - 1.1e-19 70.6 0.5 4.9e-19 68.6 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain Chromo PF00385.19 EDN11034.1 - 1.6e-13 50.0 2.5 2.3e-13 49.5 0.7 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 EDN11034.1 - 0.033 13.5 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger Mtf2_C PF14061.1 EDN11034.1 - 0.048 13.5 0.6 0.16 11.8 0.1 2.0 1 1 1 2 2 2 0 Polycomb-like MTF2 factor 2 DDE_1 PF03184.14 EDN11036.1 - 1.3e-51 174.8 0.0 2.3e-51 174.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN11036.1 - 2.1e-11 43.4 0.0 7.6e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN11036.1 - 2.2e-10 39.9 0.2 5.4e-10 38.6 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain DDE_3 PF13358.1 EDN11036.1 - 1.6e-05 24.6 0.0 3.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_28 PF13518.1 EDN11036.1 - 0.08 12.9 0.1 0.41 10.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain GCR1_C PF12550.3 EDN11037.1 - 3.9e-22 77.9 0.5 1.4e-21 76.1 0.1 2.2 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes DUF3716 PF12511.3 EDN11037.1 - 0.031 13.8 0.1 0.058 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) DDE_1 PF03184.14 EDN11038.1 - 7.3e-37 126.6 0.0 1.4e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN11038.1 - 2.1e-05 24.2 0.0 6.7e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN11038.1 - 0.0061 16.0 0.6 0.0061 16.0 0.4 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain Pox_VP8_L4R PF04498.7 EDN11038.1 - 0.069 12.4 0.0 3.7 6.7 0.0 2.7 2 1 1 3 3 3 0 Poxvirus nucleic acid binding protein VP8/L4R TraG_N PF07916.6 EDN11038.1 - 0.99 7.7 3.8 1.5 7.2 2.7 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Borrelia_P83 PF05262.6 EDN11038.1 - 2.4 6.3 20.9 3.8 5.6 14.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2229 PF09989.4 EDN11038.1 - 3.5 7.0 8.2 30 3.9 5.6 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Med17 PF10156.4 EDN11039.1 - 1.2e-128 429.3 2.3 1.9e-128 428.6 1.6 1.3 1 0 0 1 1 1 1 Subunit 17 of Mediator complex ISN1 PF06437.6 EDN11040.1 - 7.2e-188 624.3 0.0 8.2e-188 624.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Lyase_aromatic PF00221.14 EDN11040.1 - 0.01 14.3 0.0 0.014 13.8 0.0 1.1 1 0 0 1 1 1 0 Aromatic amino acid lyase Ank_4 PF13637.1 EDN11041.1 - 7.7e-13 48.5 0.1 0.00061 20.2 0.0 4.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDN11041.1 - 2.6e-11 43.6 0.0 4.2e-10 39.8 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDN11041.1 - 2.5e-09 37.0 0.0 0.00016 21.8 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EDN11041.1 - 1.3e-06 27.9 0.0 0.0017 18.1 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EDN11041.1 - 0.00026 20.9 0.1 2.3 8.7 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat ApbA_C PF08546.6 EDN11041.1 - 0.07 13.1 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal DDE_1 PF03184.14 EDN11042.1 - 2e-52 177.5 0.0 3.3e-52 176.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN11042.1 - 0.0058 16.4 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-CCHC_4 PF14392.1 EDN11042.1 - 0.13 11.9 0.1 0.31 10.7 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle HNH_2 PF13391.1 EDN11043.1 - 1.2e-11 44.1 0.0 2.8e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease DDE_3 PF13358.1 EDN11044.1 - 1.9e-32 112.0 0.0 3.6e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EDN11044.1 - 6.9e-06 26.1 0.0 2.2e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain HTH_32 PF13565.1 EDN11044.1 - 6.4e-05 23.6 0.0 0.00026 21.7 0.0 2.0 1 1 1 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.1 EDN11044.1 - 7.5e-05 22.1 0.0 0.00032 20.1 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn helix DDE_1 PF03184.14 EDN11044.1 - 8.6e-05 21.7 0.0 0.00014 21.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease PAX PF00292.13 EDN11044.1 - 0.0055 16.4 0.0 0.28 10.8 0.0 2.2 2 0 0 2 2 2 1 'Paired box' domain HTH_23 PF13384.1 EDN11044.1 - 0.078 12.6 0.6 1.2 8.8 0.0 2.9 3 1 0 3 3 3 0 Homeodomain-like domain HTH_29 PF13551.1 EDN11044.1 - 0.091 12.9 0.0 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix cNMP_binding PF00027.24 EDN11045.1 - 3.2e-39 132.6 0.0 1.3e-20 72.9 0.0 4.9 5 1 0 5 5 5 2 Cyclic nucleotide-binding domain Patatin PF01734.17 EDN11045.1 - 6.5e-19 68.6 8.6 2.1e-18 67.0 4.3 2.7 2 1 0 2 2 2 1 Patatin-like phospholipase DUF2296 PF10058.4 EDN11046.1 - 1.5e-20 72.6 0.1 2.4e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF4463 PF14703.1 EDN11046.1 - 0.082 13.4 0.1 0.28 11.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) DUF1677 PF07911.8 EDN11046.1 - 0.26 11.5 1.2 0.51 10.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) HD PF01966.17 EDN11047.1 - 1.6e-05 24.8 0.0 4.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 HD domain SecM PF06558.7 EDN11047.1 - 0.078 12.6 0.2 0.21 11.2 0.1 1.6 1 1 0 1 1 1 0 Secretion monitor precursor protein (SecM) WD40 PF00400.27 EDN11049.1 - 0.075 12.9 9.2 1.9 8.5 0.1 5.2 5 0 0 5 5 5 0 WD domain, G-beta repeat Synaptobrevin PF00957.16 EDN11050.1 - 5.1e-14 51.6 0.5 1.1e-13 50.5 0.4 1.5 1 0 0 1 1 1 1 Synaptobrevin MetRS-N PF09635.5 EDN11050.1 - 0.031 14.6 0.1 0.08 13.3 0.0 1.7 2 0 0 2 2 2 0 MetRS-N binding domain Sec63 PF02889.11 EDN11051.1 - 2.1e-143 477.2 0.0 5.9e-94 314.8 0.1 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EDN11051.1 - 1.3e-54 184.2 0.4 1.1e-28 99.8 0.5 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EDN11051.1 - 2e-16 60.3 0.0 1.7e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDN11051.1 - 9.2e-16 57.4 0.0 1e-07 31.7 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EDN11051.1 - 2.7e-07 30.7 0.1 0.035 14.2 0.0 3.2 2 2 0 2 2 2 2 AAA domain SNF2_N PF00176.18 EDN11051.1 - 1.7e-05 23.7 0.2 0.13 11.0 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_19 PF13245.1 EDN11051.1 - 1.8e-05 24.4 0.9 0.016 14.9 0.0 3.1 3 0 0 3 3 3 2 Part of AAA domain FtsK_SpoIIIE PF01580.13 EDN11051.1 - 0.0041 16.6 0.2 2.3 7.6 0.0 3.5 5 0 0 5 5 5 1 FtsK/SpoIIIE family AAA_25 PF13481.1 EDN11051.1 - 0.0061 15.9 0.2 3.4 7.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EDN11051.1 - 0.015 14.7 0.3 12 5.2 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein PhoH PF02562.11 EDN11051.1 - 0.024 13.8 0.0 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Profilin PF00235.14 EDN11053.1 - 2.3e-29 101.9 0.0 2.7e-29 101.7 0.0 1.0 1 0 0 1 1 1 1 Profilin Got1 PF04178.7 EDN11054.1 - 2.1e-19 69.7 15.4 2.6e-19 69.4 10.7 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3040 PF11239.3 EDN11054.1 - 2.4 8.2 5.0 0.55 10.3 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) SdpI PF13630.1 EDN11054.1 - 3.5 7.3 14.6 3 7.6 1.5 2.4 1 1 1 2 2 2 0 SdpI/YhfL protein family YL1_C PF08265.6 EDN11055.1 - 1.8e-16 59.3 0.2 3e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Med3 PF11593.3 EDN11055.1 - 2.2 7.4 7.8 2.6 7.1 5.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Actin PF00022.14 EDN11056.1 - 2.8e-49 167.5 0.0 7.9e-27 93.6 0.0 2.3 2 0 0 2 2 2 2 Actin DASH_Dad4 PF08650.5 EDN11056.1 - 6.1e-10 38.8 2.5 1.5e-09 37.6 1.7 1.6 1 0 0 1 1 1 1 DASH complex subunit Dad4 bZIP_1 PF00170.16 EDN11057.1 - 3.6e-07 30.0 7.6 1.1e-06 28.5 5.2 1.8 1 1 0 1 1 1 1 bZIP transcription factor DUF501 PF04417.7 EDN11057.1 - 0.02 14.7 0.3 0.04 13.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF501) HALZ PF02183.13 EDN11057.1 - 0.028 14.1 0.1 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 EDN11057.1 - 0.16 11.8 9.0 3.7 7.4 6.1 2.9 2 1 0 2 2 2 0 Basic region leucine zipper Anoctamin PF04547.7 EDN11058.1 - 1e-127 426.5 3.3 1.3e-127 426.2 2.3 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Alpha-2-MRAP_C PF06401.6 EDN11058.1 - 0.014 15.2 0.1 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain SopA PF13981.1 EDN11058.1 - 0.11 12.4 0.4 0.24 11.4 0.3 1.4 1 0 0 1 1 1 0 SopA-like central domain DUF3754 PF12576.3 EDN11058.1 - 1.6 8.3 7.7 0.77 9.3 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3754) Acetyltransf_1 PF00583.19 EDN11059.1 - 4.5e-12 45.8 0.0 7.1e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDN11059.1 - 6.2e-07 29.4 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDN11059.1 - 2e-05 24.2 0.0 3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EDN11059.1 - 0.00032 20.8 0.0 0.0007 19.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDN11059.1 - 0.00099 19.2 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDN11059.1 - 0.053 13.3 0.0 0.64 9.8 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyco_tranf_2_3 PF13641.1 EDN11061.1 - 7.9e-25 87.9 0.0 1.4e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EDN11061.1 - 1.9e-07 30.5 0.0 4.5e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EDN11061.1 - 1.9e-07 30.8 0.0 4.5e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 EST1_DNA_bind PF10373.4 EDN11061.1 - 0.00044 19.5 0.0 0.00087 18.5 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain ThiF PF00899.16 EDN11061.1 - 0.02 14.7 0.1 0.073 12.8 0.0 1.9 2 0 0 2 2 2 0 ThiF family YwiC PF14256.1 EDN11061.1 - 0.069 13.2 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 YwiC-like protein Methyltransf_23 PF13489.1 EDN11062.1 - 2.2e-16 60.0 0.0 3.3e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN11062.1 - 1.9e-05 24.2 0.1 0.00076 19.0 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN11062.1 - 2.7e-05 24.7 0.1 0.0016 18.9 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Daxx PF03344.10 EDN11062.1 - 0.011 14.2 28.5 0.014 13.8 19.7 1.1 1 0 0 1 1 1 0 Daxx Family Merozoite_SPAM PF07133.6 EDN11062.1 - 0.013 15.4 32.1 0.019 14.8 22.2 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.9 EDN11062.1 - 0.033 12.2 18.1 0.041 11.9 12.6 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 EDN11062.1 - 0.038 13.2 16.2 0.049 12.8 11.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Spore_coat_CotO PF14153.1 EDN11062.1 - 0.043 13.2 9.9 0.063 12.7 6.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO SAPS PF04499.10 EDN11062.1 - 0.058 12.0 3.1 0.062 11.9 2.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Methyltransf_12 PF08242.7 EDN11062.1 - 0.059 13.8 0.0 0.55 10.7 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EDN11062.1 - 0.12 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Nop14 PF04147.7 EDN11062.1 - 0.13 10.1 34.8 0.18 9.7 24.1 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.5 EDN11062.1 - 0.32 10.9 12.4 0.5 10.3 8.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BUD22 PF09073.5 EDN11062.1 - 0.62 9.0 26.9 0.89 8.5 18.7 1.2 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.9 EDN11062.1 - 2.5 7.5 16.5 4.9 6.6 11.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4045 PF13254.1 EDN11062.1 - 5 6.3 9.1 6.8 5.8 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Tim54 PF11711.3 EDN11062.1 - 5.5 5.4 12.1 8.1 4.9 8.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ycf1 PF05758.7 EDN11062.1 - 7.3 4.1 10.8 8.8 3.8 7.5 1.1 1 0 0 1 1 1 0 Ycf1 Sporozoite_P67 PF05642.6 EDN11062.1 - 7.4 4.3 16.5 12 3.6 11.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.6 EDN11062.1 - 8.4 4.3 17.2 11 3.9 11.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AAA PF00004.24 EDN11063.1 - 2.7e-18 66.4 0.0 5.4e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 EDN11063.1 - 1.8e-08 34.2 0.5 3.9e-08 33.1 0.2 1.8 1 1 1 2 2 2 1 BCS1 N terminal AAA_25 PF13481.1 EDN11063.1 - 7.1e-05 22.2 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDN11063.1 - 0.0015 19.2 0.0 0.004 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDN11063.1 - 0.0018 17.3 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EDN11063.1 - 0.0019 17.0 0.0 0.0031 16.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EDN11063.1 - 0.0031 17.2 0.0 0.0071 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EDN11063.1 - 0.0053 17.0 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN11063.1 - 0.0078 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EDN11063.1 - 0.022 14.1 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.1 EDN11063.1 - 0.025 14.4 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EDN11063.1 - 0.082 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EDN11063.1 - 0.12 11.9 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EDN11063.1 - 0.12 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 EDN11063.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Antimicrobial13 PF08108.6 EDN11065.1 - 0.2 11.5 1.4 0.41 10.5 1.0 1.5 1 0 0 1 1 1 0 Halocidin family Glutaredoxin2_C PF04399.8 EDN11068.1 - 0.00025 20.6 6.0 0.012 15.1 0.5 2.9 3 0 0 3 3 3 2 Glutaredoxin 2, C terminal domain L_protein_N PF15518.1 EDN11068.1 - 0.034 13.5 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 L protein N-terminus TSC22 PF01166.13 EDN11068.1 - 0.14 12.1 4.3 0.32 10.9 0.2 3.3 4 0 0 4 4 4 0 TSC-22/dip/bun family DUF4649 PF15507.1 EDN11068.1 - 0.28 10.9 1.5 11 5.9 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4649) Takusan PF04822.8 EDN11068.1 - 0.31 10.8 4.1 14 5.5 0.3 3.1 2 1 0 2 2 2 0 Takusan DUF2205 PF10224.4 EDN11068.1 - 0.45 10.1 5.0 0.21 11.1 0.3 2.6 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 EDN11068.1 - 0.54 10.6 4.2 20 5.5 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Nnf1 PF03980.9 EDN11068.1 - 0.58 10.1 6.5 0.18 11.8 0.7 2.5 2 0 0 2 2 2 0 Nnf1 F-box-like PF12937.2 EDN11070.1 - 7.2e-06 25.6 0.0 2e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN11070.1 - 0.0011 18.5 0.1 0.0043 16.6 0.0 2.1 2 0 0 2 2 2 1 F-box domain RTC4 PF14474.1 EDN11071.1 - 6.4e-30 103.6 0.1 1e-29 103.0 0.1 1.3 1 0 0 1 1 1 1 RTC4-like domain Myb_DNA-bind_6 PF13921.1 EDN11071.1 - 6.3e-06 26.1 3.1 6.3e-06 26.1 2.2 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDN11071.1 - 0.02 14.9 1.8 0.049 13.7 1.2 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain MHC_I PF00129.13 EDN11073.1 - 0.041 13.2 0.0 0.049 12.9 0.0 1.0 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 AA_permease_2 PF13520.1 EDN11074.1 - 3.7e-35 121.3 24.3 4.9e-35 120.8 16.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4231 PF14015.1 EDN11074.1 - 4.9 7.1 11.2 4.6 7.2 0.4 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) DDE_3 PF13358.1 EDN11075.1 - 2.5e-07 30.5 1.2 2.9e-07 30.3 0.8 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3114 PF11311.3 EDN11075.1 - 0.11 11.8 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) Brr6_like_C_C PF10104.4 EDN11077.1 - 1e-39 135.1 0.0 1.7e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain GtrA PF04138.9 EDN11077.1 - 0.012 15.5 0.4 0.019 14.8 0.3 1.3 1 0 0 1 1 1 0 GtrA-like protein Methyltransf_31 PF13847.1 EDN11077.1 - 0.049 13.2 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.13 EDN11078.1 - 1.5e-05 24.8 12.4 1.5e-05 24.8 8.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EDN11078.1 - 1.7e-05 23.5 0.4 0.00017 20.2 0.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Bud13 PF09736.4 EDN11082.1 - 3.7e-42 144.0 2.0 3.7e-42 144.0 1.4 2.6 3 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex Pkinase PF00069.20 EDN11083.1 - 1e-38 132.9 0.1 3.8e-24 85.2 0.1 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDN11083.1 - 4.3e-14 52.2 0.1 7.1e-10 38.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Metallophos PF00149.23 EDN11085.1 - 2.6e-09 36.7 11.6 8.4e-08 31.8 0.6 2.5 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDN11085.1 - 1.7e-05 24.7 1.1 0.0001 22.2 0.8 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FMN_dh PF01070.13 EDN11086.1 - 1e-121 406.1 0.0 1.3e-121 405.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EDN11086.1 - 7.6e-23 80.1 0.0 1.7e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EDN11086.1 - 3.8e-07 29.3 0.0 6.2e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EDN11086.1 - 0.00026 20.2 0.0 0.00043 19.5 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EDN11086.1 - 0.0028 16.6 0.0 0.0068 15.3 0.0 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Ras PF00071.17 EDN11087.1 - 1.6e-38 131.6 0.0 1.7e-36 125.0 0.0 2.0 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EDN11087.1 - 7.7e-19 68.3 0.0 1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDN11087.1 - 2.6e-11 43.0 0.0 4.1e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDN11087.1 - 0.00014 21.0 0.0 0.00017 20.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 EDN11087.1 - 0.00034 20.6 0.0 0.00054 19.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 EDN11087.1 - 0.00071 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EDN11087.1 - 0.001 19.2 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 EDN11087.1 - 0.004 16.3 0.0 0.0049 16.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EDN11087.1 - 0.015 14.8 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EDN11087.1 - 0.036 13.2 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 EDN11087.1 - 0.056 13.4 0.1 0.081 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EDN11087.1 - 0.078 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EDN11087.1 - 0.099 12.5 0.0 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EDN11087.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDN11087.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EDN11087.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase zf-C2H2_4 PF13894.1 EDN11089.1 - 4.6e-07 29.7 10.5 0.029 14.6 0.7 3.6 3 1 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN11089.1 - 7.5e-07 29.1 14.6 0.053 13.8 0.7 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDN11089.1 - 0.0057 16.8 14.0 0.018 15.3 0.9 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.1 EDN11089.1 - 0.11 12.7 4.7 0.28 11.5 0.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Zn_clus PF00172.13 EDN11090.1 - 2.1e-08 33.9 9.2 5.4e-08 32.6 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FUSC PF04632.7 EDN11092.1 - 0.11 10.9 0.4 0.13 10.6 0.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Med28 PF11594.3 EDN11094.1 - 0.0052 16.9 2.5 0.01 16.0 1.6 1.5 1 1 0 1 1 1 1 Mediator complex subunit 28 Filament PF00038.16 EDN11094.1 - 0.0073 15.8 2.6 0.012 15.0 1.8 1.3 1 0 0 1 1 1 1 Intermediate filament protein IncA PF04156.9 EDN11094.1 - 0.014 14.9 0.9 0.022 14.3 0.6 1.2 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 EDN11094.1 - 0.019 14.1 4.3 0.036 13.2 3.0 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding PEP-utilisers_N PF05524.8 EDN11094.1 - 0.068 12.9 1.1 0.12 12.2 0.7 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal SOCS_box PF07525.11 EDN11094.1 - 0.071 12.9 0.2 0.22 11.3 0.1 1.9 1 0 0 1 1 1 0 SOCS box Macoilin PF09726.4 EDN11094.1 - 0.071 11.3 3.7 0.1 10.9 2.5 1.1 1 0 0 1 1 1 0 Transmembrane protein RmuC PF02646.11 EDN11094.1 - 0.11 11.2 3.9 0.16 10.8 2.7 1.2 1 0 0 1 1 1 0 RmuC family zf-RING_5 PF14634.1 EDN11094.1 - 0.11 12.2 7.6 0.24 11.1 5.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain FlaC_arch PF05377.6 EDN11094.1 - 0.16 11.8 3.5 6.6 6.7 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DegS PF05384.6 EDN11094.1 - 0.2 10.8 6.9 0.051 12.7 2.7 1.4 2 0 0 2 2 2 0 Sensor protein DegS TMF_TATA_bd PF12325.3 EDN11094.1 - 0.23 11.1 5.8 0.65 9.7 4.0 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 EDN11094.1 - 0.38 10.5 2.6 0.56 10.0 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HALZ PF02183.13 EDN11094.1 - 0.6 9.8 4.1 0.91 9.2 0.7 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper TMF_DNA_bd PF12329.3 EDN11094.1 - 1.1 9.1 6.2 0.3 10.9 1.7 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-RING_2 PF13639.1 EDN11094.1 - 1.1 9.1 8.8 2.5 8.0 6.1 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 EDN11094.1 - 1.3 8.7 6.7 3.4 7.3 4.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Troponin PF00992.15 EDN11094.1 - 2 8.4 9.5 0.34 10.9 3.8 1.7 2 0 0 2 2 2 0 Troponin DUF4200 PF13863.1 EDN11094.1 - 2 8.3 11.7 0.096 12.6 4.3 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) Seryl_tRNA_N PF02403.17 EDN11094.1 - 3.1 7.8 7.8 0.99 9.4 3.3 1.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.20 EDN11095.1 - 6.8e-16 58.2 0.5 1.4e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.18 EDN11095.1 - 2.1e-07 30.9 0.3 0.011 15.4 0.1 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EDN11095.1 - 2.5e-06 26.6 0.1 0.00036 19.6 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EDN11095.1 - 5.4e-05 22.6 0.1 0.19 11.0 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Pkinase_Tyr PF07714.12 EDN11095.1 - 0.0022 17.1 0.4 0.055 12.5 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase HSDR_N_2 PF13588.1 EDN11095.1 - 0.012 15.3 0.0 0.83 9.4 0.0 2.5 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) YrbL-PhoP_reg PF10707.4 EDN11095.1 - 0.017 14.4 0.0 2.2 7.5 0.0 2.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.18 EDN11097.1 - 0.13 11.9 0.2 0.28 10.8 0.1 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family RNase_H PF00075.19 EDN11098.1 - 1.3e-10 41.7 0.1 1.1e-08 35.4 0.1 2.3 1 1 0 1 1 1 1 RNase H PFK PF00365.15 EDN11099.1 - 1.4e-165 549.2 0.3 6.7e-119 396.0 0.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase Glyco_hydro_76 PF03663.9 EDN11100.1 - 7.9e-145 482.8 8.8 1e-144 482.5 6.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EDN11100.1 - 0.0007 18.7 7.1 0.0056 15.7 0.0 3.1 2 1 0 3 3 3 2 Glycosyl Hydrolase Family 88 MARVEL PF01284.18 EDN11101.1 - 4e-12 46.1 11.2 4.9e-12 45.8 7.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF658 PF04936.7 EDN11102.1 - 0.065 13.0 1.6 0.077 12.8 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF658) YebO PF13974.1 EDN11102.1 - 0.11 12.3 2.9 0.14 11.9 2.0 1.2 1 0 0 1 1 1 0 YebO-like protein DDE_1 PF03184.14 EDN11103.1 - 5.7e-05 22.3 0.0 0.00034 19.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN11103.1 - 0.0092 15.7 0.1 0.037 13.8 0.0 2.2 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN11103.1 - 0.042 13.3 1.4 0.08 12.5 0.0 2.1 3 0 0 3 3 3 0 helix-turn-helix, Psq domain HTH_8 PF02954.14 EDN11103.1 - 0.068 12.7 2.0 0.5 9.9 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family HTH_Tnp_IS630 PF01710.11 EDN11103.1 - 0.12 12.0 0.0 2.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Transposase Pkinase PF00069.20 EDN11104.1 - 5.9e-05 22.3 0.0 0.00015 20.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain NmrA PF05368.8 EDN11105.1 - 1.5e-60 204.3 0.0 1.9e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN11105.1 - 1.7e-18 67.2 0.0 2.4e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EDN11105.1 - 2.7e-05 23.0 0.0 4.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EDN11105.1 - 0.039 12.9 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 EDN11105.1 - 0.054 13.4 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain MFS_1 PF07690.11 EDN11106.1 - 1.3e-29 103.0 55.5 1.3e-29 103.0 38.5 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN11106.1 - 2.8e-09 36.0 16.6 2.8e-09 36.0 11.5 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter Fungal_trans PF04082.13 EDN11107.1 - 1.2e-06 27.5 0.1 8.1e-06 24.8 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN11107.1 - 0.005 16.7 10.0 0.005 16.7 6.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EDN11108.1 - 1.4e-23 83.5 0.0 1.3e-22 80.3 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EDN11108.1 - 6.2e-06 25.3 0.0 0.0059 15.5 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDN11108.1 - 7.5e-06 26.2 0.3 0.0045 17.3 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN11108.1 - 0.00013 21.9 0.4 0.00029 20.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDN11108.1 - 0.0048 15.7 0.0 0.0073 15.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EDN11108.1 - 0.0052 15.6 0.0 0.055 12.2 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.7 EDN11108.1 - 0.017 14.0 0.0 0.75 8.6 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EDN11108.1 - 0.05 13.4 0.1 0.11 12.4 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.6 EDN11110.1 - 4.3e-34 117.6 0.1 7.3e-34 116.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2075 PF09848.4 EDN11110.1 - 0.0077 15.2 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Sterol_MT_C PF08498.5 EDN11111.1 - 6.3e-28 96.5 0.0 9.7e-28 95.9 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EDN11111.1 - 4.8e-18 65.4 0.0 9.6e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN11111.1 - 1.9e-13 50.2 0.0 2.8e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN11111.1 - 5.5e-11 42.7 0.0 1.1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN11111.1 - 7.1e-11 42.0 0.0 1.2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDN11111.1 - 1.5e-10 40.6 0.0 2.1e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EDN11111.1 - 3.1e-09 37.2 0.0 6.9e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN11111.1 - 9.9e-09 35.7 0.0 2.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN11111.1 - 2.3e-08 33.4 0.0 3.6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EDN11111.1 - 5.7e-07 29.5 0.0 1.7e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EDN11111.1 - 0.00032 20.2 0.0 0.00047 19.7 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EDN11111.1 - 0.012 14.9 0.0 0.048 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 EDN11111.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.11 EDN11111.1 - 0.04 12.2 0.0 0.056 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EDN11111.1 - 0.053 12.5 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RRM_5 PF13893.1 EDN11112.1 - 4.1e-11 42.5 0.0 8.3e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDN11112.1 - 4.6e-09 35.7 0.0 1.6e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDN11112.1 - 2.3e-05 24.2 0.0 4.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDN11112.1 - 0.00071 19.2 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Complex1_LYR PF05347.10 EDN11113.1 - 1.3e-05 24.9 0.1 2.3e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDN11113.1 - 0.00059 19.9 1.4 0.00073 19.6 0.1 1.7 2 0 0 2 2 2 1 Complex1_LYR-like DnaJ PF00226.26 EDN11114.1 - 3e-19 68.5 0.7 3e-19 68.5 0.5 2.5 2 0 0 2 2 2 1 DnaJ domain Sulfatase PF00884.18 EDN11115.1 - 5.6e-57 193.2 0.1 7.8e-57 192.7 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EDN11115.1 - 5.5e-23 80.5 0.2 1.4e-21 76.0 0.0 2.4 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EDN11115.1 - 2.2e-09 37.1 0.8 2.7e-08 33.5 0.6 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EDN11115.1 - 0.015 15.6 0.3 0.041 14.1 0.1 1.7 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Metalloenzyme PF01676.13 EDN11115.1 - 0.038 13.3 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF229 PF02995.12 EDN11115.1 - 0.062 11.7 0.0 0.076 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Amidohydro_1 PF01979.15 EDN11117.1 - 4.1e-34 118.7 0.0 5.5e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family FAD_binding_3 PF01494.14 EDN11117.1 - 4.3e-13 49.0 0.0 3e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 EDN11117.1 - 9.2e-07 28.2 0.0 0.0065 15.5 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EDN11117.1 - 1.6e-06 28.0 0.2 6.9e-06 26.0 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amidohydro_3 PF07969.6 EDN11117.1 - 5e-05 22.7 1.6 0.0059 15.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DAO PF01266.19 EDN11117.1 - 6.5e-05 21.9 0.1 0.00037 19.5 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDN11117.1 - 0.001 19.4 1.3 0.0025 18.1 0.1 2.3 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EDN11117.1 - 0.0031 16.4 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EDN11117.1 - 0.0052 15.6 0.2 0.0078 15.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EDN11117.1 - 0.013 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amidohydro_5 PF13594.1 EDN11117.1 - 0.027 14.2 0.0 0.08 12.7 0.0 1.8 1 0 0 1 1 1 0 Amidohydrolase Amidohydro_4 PF13147.1 EDN11117.1 - 0.032 14.2 2.3 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Amidohydrolase HI0933_like PF03486.9 EDN11117.1 - 0.08 11.4 0.1 0.15 10.5 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EDN11117.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family A_deaminase PF00962.17 EDN11117.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase GDC-P PF02347.11 EDN11118.1 - 4.4e-175 582.4 0.0 1.5e-161 537.9 0.0 2.5 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EDN11118.1 - 4.3e-07 29.3 0.2 9.2e-07 28.2 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Pox_A_type_inc PF04508.7 EDN11118.1 - 0.14 11.9 0.0 0.49 10.2 0.0 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF427 PF04248.7 EDN11119.1 - 2.1e-28 97.8 0.2 2.4e-28 97.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) DUF917 PF06032.7 EDN11120.1 - 1.8e-94 316.2 0.1 4.1e-93 311.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EDN11120.1 - 3.7e-49 167.3 11.5 2.9e-47 161.1 4.4 3.1 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EDN11120.1 - 2.3e-25 89.0 4.4 6.3e-23 81.1 0.1 3.2 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EDN11120.1 - 5.8e-05 21.6 1.9 0.039 12.2 0.2 2.5 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 EDN11120.1 - 0.0035 16.6 2.6 0.012 14.9 0.0 2.7 2 1 1 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 EDN11120.1 - 0.017 14.1 0.9 1.5 7.7 0.1 2.6 3 0 0 3 3 3 0 StbA protein FtsA PF14450.1 EDN11120.1 - 0.14 12.0 3.6 3 7.7 0.2 3.4 3 1 0 3 3 3 0 Cell division protein FtsA Pyridox_ox_2 PF12900.2 EDN11121.1 - 5e-25 88.0 0.0 9.8e-24 83.8 0.0 2.2 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridoxal_deC PF00282.14 EDN11123.1 - 1.3e-105 352.9 0.0 1.5e-105 352.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EDN11123.1 - 0.0012 18.0 0.1 0.0044 16.2 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase MBOAT_2 PF13813.1 EDN11124.1 - 2.7e-14 53.0 8.8 5.9e-09 35.8 0.4 2.9 3 0 0 3 3 3 2 Membrane bound O-acyl transferase family ERF PF04404.7 EDN11124.1 - 0.07 12.6 0.6 0.14 11.6 0.4 1.4 1 0 0 1 1 1 0 ERF superfamily Catalase PF00199.14 EDN11125.1 - 3.2e-160 533.0 0.3 4e-160 532.6 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EDN11125.1 - 1e-17 63.7 0.1 1.9e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive HSP9_HSP12 PF04119.7 EDN11125.1 - 0.019 15.0 0.1 0.048 13.7 0.1 1.6 1 0 0 1 1 1 0 Heat shock protein 9/12 DJ-1_PfpI PF01965.19 EDN11125.1 - 0.024 14.1 0.0 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Glyco_hydro_65m PF03632.10 EDN11126.1 - 2.1e-79 266.9 0.0 1.1e-78 264.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EDN11126.1 - 8.1e-49 166.2 0.0 1.2e-48 165.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 EDN11126.1 - 1.4e-05 25.0 0.3 3.1e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain SMC_Nse1 PF07574.8 EDN11127.1 - 8.5e-35 120.1 0.0 1.1e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex DAO PF01266.19 EDN11127.1 - 1e-24 87.1 7.3 6.9e-24 84.4 5.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase zf-RING-like PF08746.6 EDN11127.1 - 1.1e-09 38.1 9.3 1.8e-09 37.4 6.4 1.4 1 0 0 1 1 1 1 RING-like domain NAD_binding_8 PF13450.1 EDN11127.1 - 0.0015 18.5 0.1 0.0065 16.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EDN11127.1 - 0.077 12.7 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDN11127.1 - 0.078 12.8 0.0 0.38 10.6 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDN11127.1 - 0.084 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-RING_2 PF13639.1 EDN11127.1 - 0.19 11.5 7.8 0.38 10.6 5.4 1.6 1 0 0 1 1 1 0 Ring finger domain CBFD_NFYB_HMF PF00808.18 EDN11128.1 - 1.2e-15 57.2 1.3 2.6e-15 56.2 0.9 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDN11128.1 - 0.0067 16.5 0.1 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EDN11128.1 - 0.024 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Actin PF00022.14 EDN11129.1 - 8e-21 73.9 0.0 1.6e-19 69.6 0.0 2.5 2 1 0 2 2 2 1 Actin DUF1180 PF06679.7 EDN11130.1 - 0.0078 16.1 1.1 0.013 15.3 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Glyco_tranf_2_5 PF13712.1 EDN11131.1 - 0.0067 15.6 0.1 0.0076 15.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family HTH_Tnp_Tc5 PF03221.11 EDN11131.1 - 0.0085 15.8 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain UBA_e1_C PF09358.5 EDN11131.1 - 0.03 14.4 0.3 0.038 14.1 0.2 1.2 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain HTH_psq PF05225.11 EDN11131.1 - 0.037 13.5 1.1 0.08 12.5 0.0 2.2 3 0 0 3 3 3 0 helix-turn-helix, Psq domain Methyltransf_25 PF13649.1 EDN11132.1 - 5.2e-10 39.5 0.0 9.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN11132.1 - 9.9e-09 35.7 0.0 2.1e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN11132.1 - 4.2e-07 30.3 0.0 8.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN11132.1 - 5.3e-07 30.0 0.0 1.6e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN11132.1 - 9.4e-07 28.6 0.0 2.6e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN11132.1 - 2.1e-06 27.7 0.0 3.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN11132.1 - 2.4e-06 27.2 0.0 4.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDN11132.1 - 0.026 13.8 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EDN11132.1 - 0.041 12.9 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EDN11132.1 - 0.078 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MFS_1 PF07690.11 EDN11133.1 - 1.3e-33 116.1 47.3 1.3e-33 116.1 32.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN11133.1 - 3.2e-09 35.8 17.3 3.2e-09 35.8 12.0 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter FAD_binding_3 PF01494.14 EDN11134.1 - 4.7e-62 210.0 0.0 2e-61 208.0 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EDN11134.1 - 5.7e-16 58.5 0.0 1.7e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 EDN11134.1 - 0.0017 17.2 0.0 0.0048 15.7 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_3 PF13738.1 EDN11134.1 - 0.0089 16.1 1.1 0.3 11.1 0.8 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EDN11134.1 - 0.011 14.4 0.0 0.018 13.6 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EDN11134.1 - 0.063 12.1 0.0 0.11 11.4 0.0 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EDN11134.1 - 0.14 12.0 0.1 0.72 9.6 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyphos_transf PF04464.9 EDN11135.1 - 0.12 11.0 0.1 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase NmrA PF05368.8 EDN11136.1 - 3.5e-38 131.1 0.0 5.3e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN11136.1 - 1e-13 51.6 0.0 1.5e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding AMP-binding PF00501.23 EDN11137.1 - 1.4e-79 267.5 0.0 1.8e-79 267.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EDN11137.1 - 1.1e-54 185.0 0.0 2.7e-54 183.7 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 EDN11137.1 - 2.5e-12 46.8 0.7 6.7e-12 45.4 0.2 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 EDN11137.1 - 6e-10 38.9 0.0 2e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDN11137.1 - 0.02 13.5 0.0 0.071 11.8 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EDN11137.1 - 0.11 12.8 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Chromo PF00385.19 EDN11138.1 - 4e-05 23.1 0.5 7.3e-05 22.3 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Kdo PF06293.9 EDN11139.1 - 5e-05 22.4 0.2 0.00012 21.2 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN11139.1 - 0.00018 21.3 0.4 0.019 14.6 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDN11139.1 - 0.0045 16.5 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EDN11139.1 - 0.0096 15.2 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family BORG_CEP PF14957.1 EDN11140.1 - 7.8 7.4 10.1 0.52 11.2 1.7 2.3 2 0 0 2 2 2 0 Cdc42 effector Antimicrobial13 PF08108.6 EDN11143.1 - 0.23 11.4 1.4 0.41 10.5 1.0 1.4 1 0 0 1 1 1 0 Halocidin family AAA PF00004.24 EDN11144.1 - 1.5e-19 70.5 0.0 3e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 EDN11144.1 - 2e-14 53.6 1.3 3.8e-14 52.7 0.9 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA_17 PF13207.1 EDN11144.1 - 1.7e-05 25.6 0.1 7.9e-05 23.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDN11144.1 - 0.00093 18.9 0.0 0.0025 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EDN11144.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN11144.1 - 0.0011 18.9 0.2 0.0059 16.6 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EDN11144.1 - 0.0013 17.7 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EDN11144.1 - 0.0028 17.6 0.1 0.0066 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDN11144.1 - 0.0046 17.2 0.1 0.012 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EDN11144.1 - 0.0054 16.8 0.0 0.014 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDN11144.1 - 0.0063 15.5 0.0 0.0094 15.0 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EDN11144.1 - 0.016 14.9 0.1 0.064 13.0 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EDN11144.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Vac_ImportDeg PF09783.4 EDN11144.1 - 0.031 13.7 0.1 0.052 13.0 0.1 1.2 1 0 0 1 1 1 0 Vacuolar import and degradation protein ABC_tran PF00005.22 EDN11144.1 - 0.044 14.0 0.0 0.12 12.6 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_29 PF13555.1 EDN11144.1 - 0.064 12.7 0.0 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain TIP49 PF06068.8 EDN11144.1 - 0.064 11.9 0.0 0.099 11.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Zeta_toxin PF06414.7 EDN11144.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Proteasome_A_N PF10584.4 EDN11144.1 - 0.19 11.0 1.0 0.65 9.3 0.0 2.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Methyltransf_23 PF13489.1 EDN11145.1 - 6.3e-14 52.0 0.0 1.1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN11145.1 - 1.7e-06 27.6 0.0 0.0036 16.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EDN11145.1 - 6.1e-05 23.5 0.0 0.00023 21.7 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN11145.1 - 0.0048 17.3 0.0 0.012 16.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDN11145.1 - 0.11 11.6 0.0 5.4 6.0 0.0 2.6 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 EDN11145.1 - 0.11 11.8 0.0 0.66 9.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Pox_Ag35 PF03286.9 EDN11145.1 - 0.17 11.3 5.9 0.25 10.8 4.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.5 EDN11145.1 - 0.46 10.7 19.1 0.81 9.9 13.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.6 EDN11145.1 - 0.82 7.4 7.4 1.1 7.0 5.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Radial_spoke PF04712.7 EDN11145.1 - 1.2 7.7 9.3 1.7 7.3 6.4 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Prothymosin PF03247.9 EDN11145.1 - 1.4 9.1 26.5 2.4 8.3 18.3 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Daxx PF03344.10 EDN11145.1 - 1.9 6.8 19.3 2.6 6.4 13.4 1.1 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 EDN11145.1 - 2.1 7.3 10.7 2.8 6.9 7.4 1.1 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.1 EDN11145.1 - 2.8 7.5 5.9 5.2 6.7 4.1 1.4 1 0 0 1 1 1 0 FAM176 family RRN3 PF05327.6 EDN11145.1 - 2.9 5.8 4.3 3.8 5.5 3.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nucleoplasmin PF03066.10 EDN11145.1 - 3.4 7.1 20.5 6.8 6.1 14.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin TRAP_alpha PF03896.11 EDN11145.1 - 4.4 6.2 11.1 57 2.5 9.0 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF2890 PF11081.3 EDN11145.1 - 5.5 6.9 12.4 8.2 6.4 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) NOA36 PF06524.7 EDN11145.1 - 6 6.0 12.1 1.6e+02 1.3 9.8 2.0 2 0 0 2 2 2 0 NOA36 protein Glyco_tranf_2_3 PF13641.1 EDN11146.1 - 1.3e-25 90.5 0.0 1.6e-25 90.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EDN11146.1 - 2.5e-09 36.6 0.0 5.3e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EDN11146.1 - 6e-08 32.5 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EDN11146.1 - 0.0021 17.8 0.3 0.0029 17.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DUF1904 PF08921.6 EDN11146.1 - 0.079 13.0 0.2 0.18 11.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) ThiF PF00899.16 EDN11146.1 - 0.091 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 ThiF family Med30 PF11315.3 EDN11147.1 - 0.0047 17.0 0.8 0.75 9.9 0.2 2.4 2 0 0 2 2 2 2 Mediator complex subunit 30 GvpG PF05120.7 EDN11147.1 - 0.024 14.4 2.2 0.066 13.0 1.5 1.7 1 0 0 1 1 1 0 Gas vesicle protein G CorA PF01544.13 EDN11147.1 - 0.23 10.4 2.4 7.1 5.5 0.1 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein MIP-T3 PF10243.4 EDN11148.1 - 0.0002 19.9 30.0 0.0002 19.9 20.8 2.1 2 0 0 2 2 2 2 Microtubule-binding protein MIP-T3 RVT_2 PF07727.9 EDN11149.1 - 1.5e-84 282.7 0.0 2.3e-84 282.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDN11149.1 - 1.5e-11 44.4 0.0 3.5e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDN11149.1 - 6.5e-06 25.6 0.0 2.1e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain Pkinase PF00069.20 EDN11150.1 - 5.5e-12 45.3 1.7 8e-12 44.8 1.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN11150.1 - 8.9e-08 31.5 1.2 1.4e-07 30.9 0.8 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3723 PF12520.3 EDN11153.1 - 3.1e-124 415.2 2.4 2.8e-76 257.0 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) Patatin PF01734.17 EDN11154.1 - 3.9e-09 36.7 1.4 2.6e-05 24.2 0.2 3.0 3 0 0 3 3 3 2 Patatin-like phospholipase DUF3435 PF11917.3 EDN11157.1 - 7.3e-156 519.0 0.1 1.1e-155 518.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2 PF00096.21 EDN11157.1 - 0.83 10.1 12.4 6.3 7.3 1.5 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN11157.1 - 1.1 9.7 11.4 2.3 8.7 0.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Daxx PF03344.10 EDN11157.1 - 1.5 7.2 14.5 2.5 6.4 10.0 1.3 1 0 0 1 1 1 0 Daxx Family RNase_H PF00075.19 EDN11159.1 - 9.7e-15 55.0 0.0 2.2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 EDN11159.1 - 5.2e-14 52.1 0.0 8.7e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN11159.1 - 1.8e-10 40.4 0.0 4.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DDE_Tnp_1_7 PF13843.1 EDN11160.1 - 8.5e-20 71.0 1.4 1.7e-10 40.5 0.3 2.1 1 1 1 2 2 2 2 Transposase IS4 DUF624 PF04854.9 EDN11161.1 - 0.54 10.1 0.0 0.54 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF624 DUF908 PF06012.7 EDN11162.1 - 0.15 11.3 0.5 0.24 10.6 0.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Ribosomal_60s PF00428.14 EDN11162.1 - 1.5 9.2 13.7 2.8 8.4 2.2 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein Piwi PF02171.12 EDN11165.1 - 4e-15 55.5 0.0 4.7e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Piwi domain DKNYY PF13644.1 EDN11165.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 DKNYY family Transket_pyr PF02779.19 EDN11166.1 - 4.5e-45 153.3 0.0 7.4e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EDN11166.1 - 9.8e-35 119.1 0.1 3.5e-34 117.4 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain Metallophos PF00149.23 EDN11168.1 - 9.7e-10 38.1 2.7 1.6e-09 37.4 1.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ADH_zinc_N PF00107.21 EDN11169.1 - 3.3e-09 36.3 0.0 6.9e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDN11169.1 - 0.0018 18.0 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain KR PF08659.5 EDN11169.1 - 0.044 13.4 0.2 0.083 12.5 0.2 1.4 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 EDN11169.1 - 0.054 13.4 0.3 0.094 12.6 0.2 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Ank_2 PF12796.2 EDN11170.1 - 6.5e-22 77.6 0.0 3e-11 43.4 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDN11170.1 - 1.8e-14 53.4 0.1 3.4e-10 39.8 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EDN11170.1 - 2.9e-13 48.8 0.4 2.2e-06 27.1 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EDN11170.1 - 1.8e-09 37.8 0.2 1.3e-05 25.6 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN11170.1 - 3.5e-08 32.9 0.0 0.015 15.5 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Amidase PF01425.16 EDN11171.1 - 1.2e-111 373.7 1.1 1.6e-111 373.2 0.8 1.1 1 0 0 1 1 1 1 Amidase SPRY PF00622.23 EDN11172.1 - 0.0018 18.3 0.0 0.019 15.0 0.0 2.5 3 0 0 3 3 3 1 SPRY domain Bystin PF05291.6 EDN11173.1 - 1.2e-116 388.9 0.0 1.5e-116 388.6 0.0 1.1 1 0 0 1 1 1 1 Bystin Snf7 PF03357.16 EDN11174.1 - 0.00068 19.0 7.0 0.0011 18.3 4.9 1.3 1 0 0 1 1 1 1 Snf7 bZIP_2 PF07716.10 EDN11175.1 - 2.2e-10 40.2 12.0 2.2e-10 40.2 8.3 2.4 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EDN11175.1 - 7e-06 25.9 14.8 2.2e-05 24.3 10.2 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EDN11175.1 - 0.0036 17.5 11.6 0.0054 16.9 8.1 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor CENP-Q PF13094.1 EDN11175.1 - 0.0088 16.0 6.7 0.014 15.4 4.6 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Striatin PF08232.7 EDN11175.1 - 0.54 10.5 9.5 0.28 11.5 4.7 1.8 1 1 1 2 2 2 0 Striatin family APG6 PF04111.7 EDN11175.1 - 1.5 7.7 8.5 2.3 7.2 5.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EDN11175.1 - 2.9 6.7 10.0 4.1 6.2 6.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Anophelin PF10731.4 EDN11177.1 - 0.68 10.0 3.3 1.2 9.2 2.3 1.4 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Glyco_hydro_43 PF04616.9 EDN11178.1 - 4.4e-36 124.4 0.0 2.9e-26 92.2 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 zf-C2H2 PF00096.21 EDN11179.1 - 0.019 15.2 1.3 0.019 15.2 0.9 1.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDN11179.1 - 0.02 15.2 0.3 0.047 14.0 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EDN11179.1 - 0.11 12.5 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EDN11179.1 - 0.12 12.5 0.3 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDN11179.1 - 0.3 11.3 2.1 0.48 10.6 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Glypican PF01153.14 EDN11179.1 - 0.33 9.4 1.5 0.41 9.1 1.0 1.1 1 0 0 1 1 1 0 Glypican DUF1691 PF07950.6 EDN11180.1 - 6.2e-49 164.5 5.5 4e-32 110.4 2.8 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.17 EDN11180.1 - 0.016 15.0 0.2 0.016 15.0 0.1 2.5 3 0 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Iso_dh PF00180.15 EDN11181.1 - 1.1e-102 343.5 0.0 1.3e-102 343.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TRM PF02005.11 EDN11182.1 - 1.1e-108 363.5 0.0 2.1e-96 323.1 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EDN11182.1 - 0.0013 18.3 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein DUF2067 PF09840.4 EDN11182.1 - 0.0097 15.4 0.0 0.044 13.2 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2067) SRRM_C PF15230.1 EDN11182.1 - 0.014 15.4 0.2 0.014 15.4 0.2 3.8 5 0 0 5 5 5 0 Serine/arginine repetitive matrix protein C-terminus Methyltransf_31 PF13847.1 EDN11182.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.1 EDN11183.1 - 7.9e-21 74.9 0.0 2.9e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 EDN11183.1 - 4.3e-19 68.9 0.0 8.5e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 EDN11183.1 - 1.9e-14 53.4 0.0 4.3e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EDN11183.1 - 6.8e-10 38.8 0.0 1.7e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EDN11183.1 - 9.1e-05 22.4 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDN11183.1 - 0.018 14.7 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 KR domain FAM60A PF15396.1 EDN11183.1 - 0.022 14.4 0.4 0.061 13.0 0.3 1.7 1 0 0 1 1 1 0 Protein Family FAM60A Acyl_transf_1 PF00698.16 EDN11184.1 - 1.2e-83 281.1 0.0 5.6e-82 275.6 0.0 3.0 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EDN11184.1 - 1.1e-38 131.3 0.5 2.6e-38 130.1 0.0 1.9 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 EDN11184.1 - 4.6e-32 109.5 0.6 1.6e-31 107.8 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EDN11184.1 - 4.3e-20 71.8 0.0 1.7e-19 69.9 0.0 2.1 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EDN11184.1 - 0.00016 20.9 0.9 0.0052 15.9 0.6 2.4 1 1 0 1 1 1 1 Nitronate monooxygenase TFIIF_alpha PF05793.7 EDN11185.1 - 5.3e-07 28.3 70.6 1.3e-06 27.0 41.7 3.9 1 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rep-A_N PF04057.7 EDN11186.1 - 0.00045 19.9 0.0 0.00083 19.1 0.0 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain DUF383 PF04063.9 EDN11187.1 - 5.5e-70 234.8 0.0 1.4e-69 233.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EDN11187.1 - 3.2e-24 84.2 0.5 9.4e-24 82.7 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) VacJ PF04333.8 EDN11187.1 - 0.03 13.7 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 VacJ like lipoprotein Inositol_P PF00459.20 EDN11188.1 - 4.6e-64 216.3 0.0 1.7e-63 214.4 0.0 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family IBR PF01485.16 EDN11190.1 - 5e-13 48.7 38.8 1.6e-07 31.0 3.3 3.9 3 1 0 3 3 3 2 IBR domain zf-RING_5 PF14634.1 EDN11190.1 - 0.0023 17.6 7.9 0.0023 17.6 5.5 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 EDN11190.1 - 0.0052 16.5 7.5 0.0052 16.5 5.2 3.4 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDN11190.1 - 0.012 15.6 7.2 0.012 15.6 5.0 4.1 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF455 PF04305.9 EDN11191.1 - 4.7e-103 343.8 0.0 7.3e-103 343.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 EDN11191.1 - 1.1e-06 28.1 0.0 2.3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EDN11191.1 - 0.0039 16.8 0.0 0.016 14.8 0.0 2.1 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF1168 PF06658.7 EDN11191.1 - 0.026 14.0 0.3 0.043 13.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) His_Phos_2 PF00328.17 EDN11192.1 - 4.7e-112 374.7 0.1 7e-112 374.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF676 PF05057.9 EDN11192.1 - 4.8e-39 133.9 0.0 7e-27 94.1 0.0 3.3 2 1 1 3 3 3 3 Putative serine esterase (DUF676) DAGK_cat PF00781.19 EDN11192.1 - 1.9e-07 30.5 0.1 4.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RimK PF08443.6 EDN11192.1 - 2.5e-05 23.8 0.0 5.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Lipase_3 PF01764.20 EDN11192.1 - 0.063 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Utp21 PF04192.7 EDN11193.1 - 1.3e-94 315.8 0.0 2.2e-94 314.9 0.0 1.4 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EDN11193.1 - 5.9e-18 63.9 31.5 0.00028 20.6 0.1 10.1 10 0 0 10 10 10 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EDN11193.1 - 0.061 11.6 0.0 0.13 10.4 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain P12 PF12669.2 EDN11194.1 - 0.012 15.7 0.1 0.023 14.9 0.1 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family RCR PF12273.3 EDN11194.1 - 0.16 12.5 0.0 0.16 12.5 0.0 2.3 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red XPG_I_2 PF12813.2 EDN11195.1 - 1.1e-83 280.4 0.0 1.5e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 EDN11195.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 XPG I-region Fcf1 PF04900.7 EDN11196.1 - 5.9e-41 138.6 0.3 5.9e-41 138.6 0.2 1.7 2 0 0 2 2 2 1 Fcf1 FA_hydroxylase PF04116.8 EDN11197.1 - 2.1e-17 63.5 18.3 2.1e-17 63.5 12.7 1.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily LIM_bind PF01803.11 EDN11197.1 - 0.17 10.9 0.8 0.27 10.3 0.6 1.2 1 0 0 1 1 1 0 LIM-domain binding protein NCA2 PF08637.5 EDN11198.1 - 1.8e-66 224.0 0.0 3.9e-66 222.8 0.0 1.6 1 1 0 1 1 1 1 ATP synthase regulation protein NCA2 FlxA PF14282.1 EDN11198.1 - 0.85 9.5 4.8 1.6 8.7 3.3 1.4 1 0 0 1 1 1 0 FlxA-like protein zf-FCS PF06467.9 EDN11200.1 - 0.025 14.1 0.8 5.6 6.6 0.1 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_4 PF13894.1 EDN11200.1 - 0.064 13.6 0.2 0.064 13.6 0.1 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EDN11200.1 - 0.19 12.1 5.5 4.8 7.7 0.0 4.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Peptidase_S8 PF00082.17 EDN11201.1 - 7.7e-21 74.4 0.0 1.4e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Subtilase family ALAD PF00490.16 EDN11201.1 - 0.079 11.8 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase Ras PF00071.17 EDN11206.1 - 9.6e-66 220.1 0.1 1.1e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDN11206.1 - 6.3e-19 68.6 0.0 1.1e-18 67.8 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EDN11206.1 - 1.9e-13 50.0 0.1 2.3e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDN11206.1 - 3e-06 26.5 0.0 3.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDN11206.1 - 5.3e-06 26.0 0.1 2e-05 24.1 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDN11206.1 - 0.0051 16.7 0.0 0.0081 16.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EDN11206.1 - 0.017 15.2 0.0 4.8 7.4 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 EDN11206.1 - 0.027 13.7 0.0 0.16 11.1 0.0 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 EDN11206.1 - 0.084 12.0 0.1 0.26 10.4 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EDN11206.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2589 PF11655.3 EDN11206.1 - 0.13 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2589) AAA PF00004.24 EDN11208.1 - 2.5e-60 202.4 0.0 1.8e-40 138.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN11208.1 - 7.4e-10 39.1 2.7 0.00086 19.3 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 EDN11208.1 - 9e-08 32.0 0.0 0.0053 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EDN11208.1 - 2.3e-07 31.6 0.5 0.0042 17.8 0.1 2.9 2 2 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EDN11208.1 - 4.9e-07 29.9 4.0 0.045 13.8 1.2 4.3 2 2 1 3 3 3 2 AAA domain AAA_25 PF13481.1 EDN11208.1 - 1.4e-06 27.8 3.3 0.054 12.9 0.3 3.6 2 2 1 3 3 3 2 AAA domain AAA_28 PF13521.1 EDN11208.1 - 1.6e-06 28.1 0.0 0.0037 17.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EDN11208.1 - 1.7e-06 27.8 1.9 0.014 15.0 0.1 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EDN11208.1 - 2.5e-06 27.5 0.0 0.061 13.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 EDN11208.1 - 5.3e-05 22.8 2.9 1.6 8.5 0.0 5.1 6 0 0 6 6 4 2 Part of AAA domain IstB_IS21 PF01695.12 EDN11208.1 - 7.2e-05 22.2 0.1 0.26 10.6 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.8 EDN11208.1 - 0.0001 21.1 0.5 0.00059 18.6 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 EDN11208.1 - 0.00014 21.0 0.0 0.043 12.8 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus Arch_ATPase PF01637.13 EDN11208.1 - 0.0002 21.1 1.3 0.25 11.0 0.2 3.8 2 2 1 4 4 4 1 Archaeal ATPase Rad17 PF03215.10 EDN11208.1 - 0.00045 19.0 0.0 0.015 14.0 0.0 2.4 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 EDN11208.1 - 0.00046 19.8 3.5 0.88 9.2 0.4 4.1 3 2 1 4 4 4 1 NACHT domain AAA_2 PF07724.9 EDN11208.1 - 0.0007 19.5 0.0 0.0048 16.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EDN11208.1 - 0.00098 18.3 1.3 0.05 12.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EDN11208.1 - 0.0011 18.6 2.3 0.029 13.9 0.2 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EDN11208.1 - 0.0029 17.6 0.0 0.65 10.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.8 EDN11208.1 - 0.0029 16.5 0.0 2.5 6.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 EDN11208.1 - 0.0053 16.4 0.0 0.26 10.9 0.0 3.1 3 1 0 3 3 3 1 Bacterial dnaA protein AAA_33 PF13671.1 EDN11208.1 - 0.0055 16.5 0.0 0.43 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EDN11208.1 - 0.0077 15.7 0.1 0.051 13.0 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EDN11208.1 - 0.012 15.9 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDN11208.1 - 0.017 15.4 0.0 0.2 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 EDN11208.1 - 0.071 12.0 0.3 0.4 9.5 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.10 EDN11208.1 - 0.15 11.7 0.1 6.2 6.5 0.0 2.7 2 1 1 3 3 3 0 NTPase SRPRB PF09439.5 EDN11208.1 - 0.19 10.9 0.1 8.3 5.5 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EDN11208.1 - 0.39 10.9 3.9 2.6 8.3 0.3 2.5 2 0 0 2 2 2 0 ABC transporter PI3_PI4_kinase PF00454.22 EDN11211.1 - 6.4e-51 173.0 0.0 1.4e-50 171.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EDN11211.1 - 2.9e-46 158.0 1.5 1.3e-45 155.9 0.8 2.3 2 0 0 2 2 2 1 FAT domain UME PF08064.8 EDN11211.1 - 1.1e-39 134.7 2.7 2.6e-39 133.4 0.4 2.9 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 EDN11211.1 - 2.1e-13 49.4 0.9 5.6e-13 48.0 0.0 2.3 3 0 0 3 3 3 1 FATC domain TPR_14 PF13428.1 EDN11211.1 - 0.1 13.2 3.0 17 6.3 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat dCMP_cyt_deam_1 PF00383.17 EDN11212.1 - 6.8e-11 41.7 0.0 9e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region NADH_u_ox_C PF12853.2 EDN11213.1 - 4.7e-36 122.3 0.4 1.6e-34 117.4 0.1 2.1 2 0 0 2 2 2 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 EDN11213.1 - 6.6e-24 83.9 8.0 4e-23 81.4 5.5 2.0 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF2219 PF09982.4 EDN11214.1 - 0.021 13.6 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2219) Dzip-like_N PF13815.1 EDN11214.1 - 0.031 14.0 7.5 0.15 11.8 5.2 2.0 1 1 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF106 PF01956.11 EDN11214.1 - 0.069 12.6 2.3 0.091 12.2 1.6 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 G5 PF07501.7 EDN11214.1 - 0.087 12.7 2.6 0.19 11.7 1.8 1.8 1 1 0 1 1 1 0 G5 domain DUF904 PF06005.7 EDN11214.1 - 0.81 10.0 4.6 1.4 9.2 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 EDN11214.1 - 1.9 8.3 5.1 4.5 7.1 2.6 2.1 1 1 1 2 2 2 0 Basic region leucine zipper COX16 PF14138.1 EDN11215.1 - 6.1e-32 109.6 0.1 7.8e-32 109.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Nic96 PF04097.9 EDN11216.1 - 1.2e-214 713.9 0.0 1.5e-214 713.6 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 RibD_C PF01872.12 EDN11217.1 - 1.4e-30 106.4 0.0 2.2e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 RibD C-terminal domain Mito_fiss_reg PF05308.6 EDN11217.1 - 4.5 6.5 5.8 9.8 5.4 4.0 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator RCC1 PF00415.13 EDN11219.1 - 2.1e-50 168.7 18.2 1e-11 44.8 0.1 8.1 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDN11219.1 - 4.6e-31 105.7 39.1 1.4e-07 30.8 0.7 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Neuromodulin_N PF10580.4 EDN11219.1 - 0.21 11.2 0.7 0.47 10.1 0.5 1.5 1 0 0 1 1 1 0 Gap junction protein N-terminal region Swi3 PF07962.7 EDN11220.1 - 3.1e-31 106.8 0.1 5.6e-31 106.0 0.1 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Pkinase PF00069.20 EDN11221.1 - 5.4e-09 35.5 0.0 9.7e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN11221.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN11221.1 - 0.038 13.0 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Y_phosphatase PF00102.22 EDN11222.1 - 1.6e-56 191.3 0.0 4.5e-55 186.5 0.0 2.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EDN11222.1 - 1.6e-09 38.0 0.0 4.7e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 EDN11222.1 - 0.0072 15.9 0.1 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EDN11222.1 - 0.011 15.9 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family F-box PF00646.28 EDN11225.1 - 0.0047 16.5 0.0 0.0095 15.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDN11225.1 - 0.054 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 F-box-like FGGY_C PF02782.11 EDN11227.1 - 8.4e-53 178.9 0.2 1.3e-52 178.2 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EDN11227.1 - 1.2e-24 87.0 0.0 2.4e-23 82.7 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EDN11227.1 - 0.017 14.3 0.0 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Na_Ca_ex PF01699.19 EDN11228.1 - 3.6e-19 68.7 8.9 3.6e-19 68.7 6.2 4.5 5 0 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EDN11228.1 - 2.4e-14 53.4 8.9 2.4e-14 53.4 6.2 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF307) AAA PF00004.24 EDN11229.1 - 7e-44 149.2 0.0 1.1e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EDN11229.1 - 1.7e-07 31.2 0.0 3.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EDN11229.1 - 3.5e-07 30.0 0.0 9.2e-07 28.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDN11229.1 - 1.6e-06 28.2 0.0 3.4e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDN11229.1 - 4e-06 27.0 0.1 0.00021 21.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN11229.1 - 4.8e-05 23.0 0.1 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EDN11229.1 - 7.9e-05 23.4 0.0 0.00018 22.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDN11229.1 - 9e-05 21.6 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EDN11229.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EDN11229.1 - 0.001 17.9 0.0 0.0018 17.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EDN11229.1 - 0.0016 18.3 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDN11229.1 - 0.0018 18.1 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDN11229.1 - 0.0024 16.9 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EDN11229.1 - 0.0039 16.7 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EDN11229.1 - 0.004 17.1 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EDN11229.1 - 0.007 15.5 0.1 0.015 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EDN11229.1 - 0.0075 15.4 0.0 0.016 14.2 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_18 PF13238.1 EDN11229.1 - 0.0087 16.3 0.1 0.047 13.9 0.0 2.3 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.8 EDN11229.1 - 0.015 14.2 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 EDN11229.1 - 0.016 14.4 0.0 0.052 12.7 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 EDN11229.1 - 0.018 14.4 0.1 0.079 12.3 0.0 1.8 1 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EDN11229.1 - 0.018 14.5 0.0 0.086 12.3 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.1 EDN11229.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDN11229.1 - 0.041 14.0 0.0 0.075 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EDN11229.1 - 0.057 13.4 0.0 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EDN11229.1 - 0.066 12.8 0.0 0.37 10.4 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 EDN11229.1 - 0.076 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EDN11229.1 - 0.091 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Histone PF00125.19 EDN11229.1 - 0.097 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF2072 PF09845.4 EDN11229.1 - 0.14 12.1 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) F-box-like PF12937.2 EDN11230.1 - 0.00029 20.5 0.1 0.0008 19.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN11230.1 - 0.033 13.8 0.2 0.1 12.2 0.2 1.9 1 0 0 1 1 1 0 F-box domain CobW_C PF07683.9 EDN11230.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain CCT PF06203.9 EDN11230.1 - 0.22 11.1 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 CCT motif UFD1 PF03152.9 EDN11231.1 - 5.4e-25 87.5 0.0 5.8e-20 71.1 0.0 3.5 3 1 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 Bac_surface_Ag PF01103.18 EDN11232.1 - 3.5e-32 112.1 0.0 5.5e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.12 EDN11232.1 - 1.5e-05 24.5 14.0 0.00083 18.9 5.0 2.6 2 0 0 2 2 2 2 Yip1 domain UQ_con PF00179.21 EDN11233.1 - 3e-09 36.4 0.0 4.2e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme APH PF01636.18 EDN11235.1 - 0.074 12.7 0.0 0.093 12.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans_2 PF11951.3 EDN11237.1 - 2.3e-07 29.7 0.0 5.8e-07 28.4 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Dishevelled PF02377.10 EDN11237.1 - 0.17 12.0 6.5 0.045 13.9 0.9 2.5 2 0 0 2 2 2 0 Dishevelled specific domain Cyto_heme_lyase PF01265.12 EDN11238.1 - 8.2e-78 261.5 0.0 9.5e-78 261.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF676 PF05057.9 EDN11239.1 - 0.00089 18.6 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EDN11239.1 - 0.02 14.7 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4386 PF14329.1 EDN11239.1 - 0.027 13.9 2.4 0.047 13.1 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) Abhydrolase_5 PF12695.2 EDN11239.1 - 0.057 13.1 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EDN11239.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.4 2 0 0 2 2 2 0 PGAP1-like protein DUF900 PF05990.7 EDN11239.1 - 0.069 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) ABC1 PF03109.11 EDN11240.1 - 1.8e-23 82.7 0.0 8.2e-14 51.5 0.0 2.4 1 1 1 2 2 2 2 ABC1 family APH PF01636.18 EDN11240.1 - 0.011 15.4 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EDN11240.1 - 0.056 12.7 0.0 0.46 9.8 0.0 2.0 2 0 0 2 2 2 0 RIO1 family SLAC1 PF03595.12 EDN11241.1 - 5.2e-79 265.2 45.7 6e-79 265.0 31.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Pro_CA PF00484.14 EDN11242.1 - 2.8e-28 98.8 0.1 3.6e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase adh_short PF00106.20 EDN11243.1 - 7.3e-22 78.0 0.0 1.1e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDN11243.1 - 1.8e-10 41.0 0.0 3.1e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EDN11243.1 - 0.0058 15.9 0.0 0.012 14.8 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family ATP-grasp_2 PF08442.5 EDN11244.1 - 1.3e-78 263.0 1.5 1.3e-78 263.0 1.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 EDN11244.1 - 5.8e-25 87.6 0.3 1.5e-24 86.3 0.2 1.7 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EDN11244.1 - 5.1e-09 35.6 1.8 6.9e-09 35.2 0.5 1.8 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EDN11244.1 - 0.0019 17.7 2.4 0.0078 15.7 0.2 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain B2 PF11473.3 EDN11244.1 - 0.0047 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA binding protein B2 ATP-grasp_4 PF13535.1 EDN11244.1 - 0.011 15.5 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 EDN11244.1 - 0.04 13.3 0.0 1.2 8.6 0.0 2.9 2 1 1 3 3 3 0 RimK-like ATP-grasp domain ATPgrasp_Ter PF15632.1 EDN11244.1 - 0.058 12.1 0.0 0.14 10.9 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Ribosomal_S11 PF00411.14 EDN11244.1 - 0.13 12.4 1.8 3.9 7.6 0.0 2.7 3 0 0 3 3 3 0 Ribosomal protein S11 DUF3245 PF11595.3 EDN11245.1 - 2e-49 167.6 3.4 2e-49 167.6 2.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3245) HSF_DNA-bind PF00447.12 EDN11246.1 - 2.8e-21 75.6 0.9 6.4e-21 74.4 0.6 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding zf-C4pol PF14260.1 EDN11246.1 - 0.048 13.6 0.1 0.098 12.6 0.1 1.4 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Pribosyltran PF00156.22 EDN11247.1 - 7.4e-05 22.4 0.5 0.00029 20.5 0.4 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DPM3 PF08285.6 EDN11248.1 - 3.3e-13 49.2 0.0 3.4e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) KAP PF05804.7 EDN11249.1 - 1.6e-07 29.7 0.0 5.5e-05 21.2 0.0 2.2 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) Arm PF00514.18 EDN11249.1 - 0.22 11.3 1.5 32 4.5 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Oxidored-like PF09791.4 EDN11250.1 - 1.2e-25 88.7 4.4 2.5e-25 87.6 3.1 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Actin PF00022.14 EDN11251.1 - 3.5e-93 312.1 0.0 7.4e-92 307.7 0.0 2.1 1 1 1 2 2 2 2 Actin GCIP PF13324.1 EDN11252.1 - 0.00012 21.4 0.1 0.16 11.1 0.0 3.0 2 1 1 3 3 3 2 Grap2 and cyclin-D-interacting LRR_4 PF12799.2 EDN11253.1 - 1.2e-38 130.0 54.4 9.8e-10 37.8 1.2 10.5 7 2 3 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDN11253.1 - 3.6e-27 93.8 53.0 3.3e-07 29.9 2.9 8.7 6 2 4 10 10 10 9 Leucine rich repeat LRR_7 PF13504.1 EDN11253.1 - 2.6e-20 68.9 43.9 0.086 13.0 0.1 14.6 16 0 0 16 16 16 9 Leucine rich repeat LRR_1 PF00560.28 EDN11253.1 - 9.8e-19 64.5 53.2 0.047 13.7 0.1 15.3 15 3 1 16 16 16 7 Leucine Rich Repeat LRR_6 PF13516.1 EDN11253.1 - 7.7e-10 37.8 43.5 0.48 10.6 0.0 14.2 13 3 2 15 15 15 6 Leucine Rich repeat Ribosomal_L13e PF01294.13 EDN11255.1 - 3.3e-67 225.4 4.2 4.6e-67 224.9 2.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Nucleo_P87 PF07267.6 EDN11257.1 - 0.45 9.1 9.1 0.35 9.4 4.0 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 HTH_7 PF02796.10 EDN11258.1 - 0.0036 17.1 0.0 0.01 15.6 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase HTH_38 PF13936.1 EDN11258.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain BCS1_N PF08740.6 EDN11259.1 - 5.2e-41 140.3 0.1 8.6e-41 139.6 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDN11259.1 - 7.5e-10 39.1 0.0 2.1e-08 34.4 0.0 2.5 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDN11259.1 - 0.014 15.3 0.1 0.062 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EDN11259.1 - 0.038 14.8 0.4 0.14 12.9 0.0 2.3 2 2 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EDN11259.1 - 0.039 13.8 0.3 0.79 9.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EDN11259.1 - 0.049 12.7 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 EDN11259.1 - 0.049 13.0 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 EDN11259.1 - 0.074 11.6 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase AAA_5 PF07728.9 EDN11259.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EDN11259.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.16 EDN11260.1 - 7.6e-10 38.6 5.3 1.6e-09 37.5 3.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EDN11260.1 - 1.9e-07 30.7 7.7 3.9e-07 29.7 5.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EDN11260.1 - 0.46 10.8 8.7 0.083 13.1 3.0 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor DDE_1 PF03184.14 EDN11262.1 - 6e-51 172.6 0.0 1.4e-50 171.4 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EDN11262.1 - 3.6e-06 26.8 0.0 7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease SRF-TF PF00319.13 EDN11265.1 - 0.00025 20.2 0.1 0.0015 17.6 0.0 2.1 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Pkinase PF00069.20 EDN11266.1 - 9.8e-08 31.4 0.0 1.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EDN11266.1 - 8.3e-06 25.0 0.0 1.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN11266.1 - 1.4e-05 24.9 0.0 0.00016 21.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDN11266.1 - 0.00036 19.9 0.0 0.00092 18.6 0.0 1.6 1 1 0 1 1 1 1 RIO1 family WaaY PF06176.6 EDN11266.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Alpha_L_fucos PF01120.12 EDN11266.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-fucosidase HIF-1 PF11413.3 EDN11266.1 - 0.35 10.1 2.8 0.72 9.0 1.9 1.5 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 Rep-A_N PF04057.7 EDN11267.1 - 0.13 12.0 0.1 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain DUF624 PF04854.9 EDN11267.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF624 DUF4517 PF15006.1 EDN11268.1 - 0.011 15.5 0.5 0.013 15.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4517) DUF3187 PF11383.3 EDN11268.1 - 0.041 13.0 0.5 0.047 12.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3187) Haemagg_act PF05860.8 EDN11268.1 - 2.3 8.0 12.9 3.6 7.3 9.0 1.5 1 1 0 1 1 1 0 haemagglutination activity domain ECH PF00378.15 EDN11270.1 - 5.4e-14 51.9 0.1 6.4e-14 51.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family TIMELESS PF04821.9 EDN11271.1 - 1.4e-62 211.4 0.9 8.8e-53 179.2 0.0 2.7 1 1 1 2 2 2 2 Timeless protein TIMELESS_C PF05029.8 EDN11271.1 - 1.3e-50 172.8 15.7 6.2e-43 147.5 0.0 3.2 2 1 1 3 3 3 3 Timeless protein C terminal region UCH PF00443.24 EDN11271.1 - 0.0023 17.1 0.6 0.35 9.9 0.0 3.0 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase 3HCDH_N PF02737.13 EDN11272.1 - 2.6e-54 183.5 2.3 3.8e-54 183.0 1.6 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EDN11272.1 - 2.9e-34 117.3 0.0 1.1e-33 115.4 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ApbA PF02558.11 EDN11272.1 - 9.8e-07 28.3 0.2 0.0006 19.2 0.1 2.3 1 1 0 2 2 2 2 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 EDN11272.1 - 3e-06 27.1 0.5 7.5e-06 25.8 0.3 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EDN11272.1 - 5.7e-05 22.8 0.4 9.3e-05 22.2 0.3 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EDN11272.1 - 0.00061 18.8 0.1 0.00074 18.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EDN11272.1 - 0.001 18.4 0.0 0.0021 17.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EDN11272.1 - 0.0045 15.9 0.0 0.0069 15.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDN11272.1 - 0.0087 16.4 0.3 0.019 15.3 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDN11272.1 - 0.012 15.4 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EDN11272.1 - 0.013 15.0 0.1 0.021 14.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EDN11272.1 - 0.014 14.5 0.3 0.031 13.4 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EDN11272.1 - 0.021 15.0 0.1 0.037 14.2 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Methyltransf_32 PF13679.1 EDN11272.1 - 0.071 12.7 0.0 0.18 11.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox_3 PF13738.1 EDN11272.1 - 0.078 13.0 0.9 0.29 11.1 0.7 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RsbU_N PF08673.5 EDN11272.1 - 0.086 12.8 0.1 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain F420_oxidored PF03807.12 EDN11272.1 - 0.088 13.2 2.3 0.2 12.0 1.0 2.2 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EDN11272.1 - 0.2 11.6 1.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain RVT_1 PF00078.22 EDN11275.1 - 5.3e-11 42.2 0.1 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.21 EDN11275.1 - 1.3 9.5 9.4 2.3 8.7 5.5 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Phage_lysis PF03245.8 EDN11276.1 - 0.022 14.7 1.3 0.028 14.3 0.1 1.7 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Nairo_nucleo PF02477.10 EDN11276.1 - 0.07 11.8 0.0 0.094 11.4 0.0 1.1 1 0 0 1 1 1 0 Nucleocapsid N protein DUF3435 PF11917.3 EDN11277.1 - 5e-158 526.2 0.0 6.5e-158 525.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C3HC4_3 PF13920.1 EDN11278.1 - 0.0016 18.0 9.9 0.0026 17.3 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DegS PF05384.6 EDN11278.1 - 0.0048 16.1 2.4 0.007 15.5 1.6 1.2 1 0 0 1 1 1 1 Sensor protein DegS ADIP PF11559.3 EDN11278.1 - 0.0079 16.1 1.8 0.011 15.6 1.3 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding MAD PF05557.8 EDN11278.1 - 0.016 13.3 1.0 0.016 13.2 0.7 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein zf-RING_5 PF14634.1 EDN11278.1 - 0.017 14.8 6.4 0.031 13.9 4.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Fib_alpha PF08702.5 EDN11278.1 - 0.023 14.7 0.7 0.038 14.1 0.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family zf-C3HC4 PF00097.20 EDN11278.1 - 0.025 14.2 6.3 0.062 12.9 4.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Seryl_tRNA_N PF02403.17 EDN11278.1 - 0.031 14.2 0.9 0.046 13.7 0.2 1.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Med28 PF11594.3 EDN11278.1 - 0.036 14.3 0.8 0.056 13.6 0.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 28 PspA_IM30 PF04012.7 EDN11278.1 - 0.052 12.9 2.3 0.069 12.5 1.6 1.1 1 0 0 1 1 1 0 PspA/IM30 family DUF4435 PF14491.1 EDN11278.1 - 0.099 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4435) TMF_DNA_bd PF12329.3 EDN11278.1 - 0.12 12.2 1.5 0.17 11.6 1.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2730 PF10805.3 EDN11278.1 - 0.13 12.0 0.5 0.18 11.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) zf-RING_2 PF13639.1 EDN11278.1 - 0.17 11.7 8.1 0.41 10.5 5.6 1.7 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 EDN11278.1 - 0.22 11.5 8.5 0.45 10.5 5.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RmuC PF02646.11 EDN11278.1 - 0.23 10.2 3.3 0.3 9.8 2.3 1.1 1 0 0 1 1 1 0 RmuC family Acetyltransf_1 PF00583.19 EDN11281.1 - 0.0067 16.4 0.0 0.0073 16.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EDN11281.1 - 0.038 13.8 0.1 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tegument_dsDNA PF12818.2 EDN11281.1 - 0.1 11.4 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 dsDNA viral tegument protein Acetyltransf_7 PF13508.1 EDN11281.1 - 0.11 12.6 0.1 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Exo_endo_phos_2 PF14529.1 EDN11282.1 - 1.4e-22 79.5 0.1 3e-22 78.4 0.1 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN11282.1 - 5.8e-08 32.9 0.4 9.6e-08 32.2 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HALZ PF02183.13 EDN11282.1 - 1.3e-05 24.8 0.8 2.5e-05 23.8 0.5 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper ATG16 PF08614.6 EDN11282.1 - 0.02 14.7 0.5 0.02 14.7 0.4 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 EDN11282.1 - 0.031 14.6 0.6 0.086 13.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Kinesin-relat_1 PF12711.2 EDN11282.1 - 0.11 12.9 0.2 0.11 12.9 0.1 1.9 2 0 0 2 2 2 0 Kinesin motor TSC22 PF01166.13 EDN11282.1 - 0.15 12.0 2.4 0.45 10.5 0.1 2.8 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF904 PF06005.7 EDN11282.1 - 7.5 6.9 7.4 0.28 11.5 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF904) zf-C2H2 PF00096.21 EDN11283.1 - 5.9e-05 23.1 0.6 5.9e-05 23.1 0.4 3.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EDN11283.1 - 0.00054 19.7 0.3 0.00054 19.7 0.2 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDN11283.1 - 0.00076 19.6 1.2 0.00076 19.6 0.8 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDN11283.1 - 0.00089 19.4 7.9 0.0014 18.7 0.4 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 EDN11283.1 - 0.22 11.6 6.3 0.52 10.4 4.3 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 EDN11283.1 - 2.9 8.2 8.1 0.43 10.8 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type F-box-like PF12937.2 EDN11284.1 - 1.4e-07 31.0 0.1 4.2e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN11284.1 - 0.0011 18.5 0.0 0.0024 17.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain DUF1312 PF07009.6 EDN11286.1 - 0.017 14.9 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1312) Methyltransf_23 PF13489.1 EDN11287.1 - 6.7e-15 55.1 0.0 1.2e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN11287.1 - 8e-07 28.7 0.0 0.002 17.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EDN11287.1 - 2.7e-06 27.9 0.2 0.00013 22.4 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN11287.1 - 0.0023 18.3 0.0 0.0048 17.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain SAPS PF04499.10 EDN11287.1 - 0.0058 15.3 6.4 0.0059 15.3 4.4 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Spore_coat_CotO PF14153.1 EDN11287.1 - 0.012 15.0 13.4 0.019 14.4 9.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO MTS PF05175.9 EDN11287.1 - 0.16 11.3 0.0 3.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Ycf1 PF05758.7 EDN11287.1 - 2.9 5.4 13.9 3.4 5.2 9.7 1.1 1 0 0 1 1 1 0 Ycf1 SDA1 PF05285.7 EDN11287.1 - 3.8 6.6 52.0 5.7 6.1 36.0 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EDN11287.1 - 5.8 4.7 57.6 8.2 4.1 39.9 1.1 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.20 EDN11291.1 - 3.7e-09 36.1 0.0 6.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN11291.1 - 0.0077 15.9 0.0 0.03 14.0 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EDN11291.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.17 EDN11291.1 - 0.18 11.1 0.0 0.41 9.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Myb_DNA-bind_6 PF13921.1 EDN11292.1 - 0.0055 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SM-ATX PF14438.1 EDN11293.1 - 0.00023 21.0 0.0 0.00032 20.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.17 EDN11293.1 - 0.00036 20.0 0.0 0.00055 19.4 0.0 1.3 1 1 0 1 1 1 1 LSM domain RNase_H PF00075.19 EDN11297.1 - 4.6e-15 56.1 0.0 7.6e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 RNase H CEP44 PF15007.1 EDN11298.1 - 0.095 12.4 0.3 0.11 12.2 0.2 1.1 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 Ala_racemase_N PF01168.15 EDN11299.1 - 2.6e-16 59.8 0.0 2.6e-15 56.5 0.0 2.0 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.15 EDN11300.1 - 4.1e-126 421.4 4.8 4.9e-126 421.1 3.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EDN11300.1 - 1.8e-43 147.0 0.0 3.8e-43 146.0 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EDN11300.1 - 1.4e-19 70.5 0.1 3.1e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain STAT_int PF02865.12 EDN11300.1 - 0.039 13.9 1.5 0.18 11.7 0.2 2.4 2 0 0 2 2 2 0 STAT protein, protein interaction domain DUF1096 PF06493.6 EDN11301.1 - 3.7 7.5 39.2 2.4 8.1 11.8 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1096) Homeobox PF00046.24 EDN11302.1 - 5.2e-12 45.1 1.9 1.1e-11 44.1 1.3 1.6 1 0 0 1 1 1 1 Homeobox domain Rif1_N PF12231.3 EDN11302.1 - 0.056 12.4 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal efThoc1 PF11957.3 EDN11303.1 - 7.2e-174 578.8 3.8 9.3e-174 578.5 2.6 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor AAA_12 PF13087.1 EDN11304.1 - 7.7e-26 90.7 0.0 1.4e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EDN11304.1 - 2.1e-22 79.8 0.0 3.7e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDN11304.1 - 1.9e-09 37.1 0.1 1.1e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EDN11304.1 - 7.7e-06 25.6 0.0 0.0035 16.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EDN11304.1 - 3.5e-05 23.7 0.0 6.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EDN11304.1 - 8.4e-05 22.0 0.0 0.00049 19.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EDN11304.1 - 0.0012 18.3 0.2 0.14 11.6 0.1 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 EDN11304.1 - 0.0015 19.3 0.1 0.5 11.1 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 EDN11304.1 - 0.0057 16.8 0.0 0.018 15.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN11304.1 - 0.0076 16.3 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDN11304.1 - 0.018 15.0 0.0 0.058 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain DEAD PF00270.24 EDN11304.1 - 0.021 14.3 0.0 0.054 12.9 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF2075 PF09848.4 EDN11304.1 - 0.024 13.6 0.5 0.046 12.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EDN11304.1 - 0.029 13.6 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Zeta_toxin PF06414.7 EDN11304.1 - 0.03 13.4 0.3 0.097 11.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 EDN11304.1 - 0.043 13.9 0.1 0.75 9.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 EDN11304.1 - 0.054 13.2 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.12 EDN11304.1 - 0.066 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KaiC PF06745.8 EDN11304.1 - 0.093 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 EDN11304.1 - 0.093 12.6 0.0 0.63 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.10 EDN11304.1 - 0.12 11.2 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PIF1 PF05970.9 EDN11304.1 - 0.17 10.7 0.0 8.4 5.2 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase NB-ARC PF00931.17 EDN11304.1 - 0.2 10.4 0.0 0.39 9.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RecA PF00154.16 EDN11304.1 - 0.31 10.0 0.0 0.54 9.2 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein 4HBT PF03061.17 EDN11305.1 - 2.5e-13 49.9 0.1 3.7e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EDN11305.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4442) Tfb2 PF03849.9 EDN11306.1 - 1.2e-133 445.2 3.7 1.2e-114 382.7 0.5 2.0 1 1 1 2 2 2 2 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EDN11306.1 - 2.1e-06 27.5 0.0 3.3e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SinI PF08671.5 EDN11306.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Anti-repressor SinI PhzC-PhzF PF02567.11 EDN11308.1 - 5.6e-42 143.8 0.0 2.7e-41 141.6 0.0 1.8 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein PFL PF02901.10 EDN11309.1 - 0.003 16.0 1.6 0.003 16.0 1.1 1.4 1 1 1 2 2 2 1 Pyruvate formate lyase DUF3819 PF12842.2 EDN11309.1 - 0.037 13.6 0.0 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) DUF3867 PF12983.2 EDN11309.1 - 0.12 12.2 1.2 0.15 12.0 0.8 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3867) DUF3746 PF12562.3 EDN11309.1 - 0.12 12.1 1.6 0.18 11.7 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3746) DUF4404 PF14357.1 EDN11309.1 - 0.19 12.1 1.3 2.4 8.6 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF4113 PF13438.1 EDN11311.1 - 0.0074 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4113) IBR PF01485.16 EDN11312.1 - 1.9e-11 43.6 42.1 3e-07 30.1 4.4 3.7 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EDN11312.1 - 0.00071 19.3 6.3 0.00071 19.3 4.4 3.7 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EDN11312.1 - 0.0034 17.0 9.9 0.0034 17.0 6.9 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDN11312.1 - 2.7 7.9 27.4 0.1 12.5 3.4 3.9 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING RNase_H PF00075.19 EDN11314.1 - 1.2e-09 38.5 0.0 2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EDN11314.1 - 0.04 13.6 0.1 0.16 11.7 0.1 2.0 1 1 0 1 1 1 0 Reverse transcriptase-like SCHIP-1 PF10148.4 EDN11315.1 - 0.013 14.8 2.1 0.017 14.5 1.5 1.1 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 IncA PF04156.9 EDN11315.1 - 0.054 13.0 1.2 0.063 12.8 0.8 1.2 1 0 0 1 1 1 0 IncA protein Presenilin PF01080.12 EDN11315.1 - 1 8.1 3.9 0.98 8.1 2.7 1.2 1 0 0 1 1 1 0 Presenilin HisKA_3 PF07730.8 EDN11315.1 - 1 9.7 3.9 0.27 11.5 0.3 1.8 2 0 0 2 2 2 0 Histidine kinase RVT_1 PF00078.22 EDN11316.1 - 5.1e-26 91.3 0.0 1.1e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EDN11316.1 - 1.6e-15 56.7 0.0 9.6e-15 54.2 0.0 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EDN11316.1 - 0.00048 20.1 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EDN11316.1 - 0.00053 19.7 4.1 0.00053 19.7 2.9 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 EDN11316.1 - 0.99 9.1 12.8 3.1 7.5 1.0 2.6 1 1 1 2 2 2 0 Zinc knuckle Ribosomal_S17 PF00366.15 EDN11320.1 - 8.8e-31 105.7 1.5 1.3e-30 105.2 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.1 EDN11321.1 - 0 1227.7 50.7 0 1227.7 35.2 1.7 2 0 0 2 2 2 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EDN11321.1 - 5.2e-115 383.5 3.9 9.5e-115 382.7 2.7 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein MFS_1 PF07690.11 EDN11322.1 - 1.3e-44 152.3 22.4 1.3e-44 152.3 15.5 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3754 PF12576.3 EDN11322.1 - 0.41 10.2 3.9 9.2 5.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Pil1 PF13805.1 EDN11323.1 - 1.2e-157 523.0 0.8 1.5e-157 522.7 0.5 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EDN11323.1 - 0.022 14.1 1.9 0.034 13.4 0.7 1.7 1 1 1 2 2 2 0 FAM92 protein SUR7 PF06687.7 EDN11324.1 - 2.8e-47 161.0 3.4 3.4e-47 160.7 2.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF1625 PF07787.7 EDN11324.1 - 2.2 7.4 5.9 3.7 6.7 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) Ank_2 PF12796.2 EDN11325.1 - 3.9e-51 171.3 0.0 5e-17 62.0 0.3 5.3 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EDN11325.1 - 3.9e-36 121.0 0.2 1.1e-05 25.0 0.0 9.6 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 EDN11325.1 - 1.5e-32 111.3 3.2 4.1e-09 36.7 0.0 6.8 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDN11325.1 - 7e-32 108.7 3.8 6.8e-09 35.6 0.1 6.6 1 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDN11325.1 - 6.6e-31 103.2 0.3 0.013 15.7 0.0 9.3 9 0 0 9 9 9 8 Ankyrin repeat DctQ PF04290.7 EDN11325.1 - 0.041 13.6 0.6 0.91 9.2 0.1 2.6 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component TPP1 PF10341.4 EDN11326.1 - 5.4e-17 61.6 0.0 1.4e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD PIP5K PF01504.13 EDN11327.1 - 1.5e-55 188.0 0.1 3.9e-55 186.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EDN11327.1 - 9.2e-30 103.6 0.0 1.4e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_transf_5 PF08323.6 EDN11327.1 - 0.056 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain PK PF00224.16 EDN11328.1 - 1.9e-156 520.0 4.9 2.6e-156 519.6 3.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EDN11328.1 - 3e-29 100.9 0.0 9.8e-29 99.2 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EDN11328.1 - 2.8e-05 23.1 1.1 6.2e-05 21.9 0.7 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Ribosomal_S8 PF00410.14 EDN11329.1 - 7.4e-19 67.8 0.0 1.6e-18 66.8 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S8 Iso_dh PF00180.15 EDN11332.1 - 9.6e-95 317.4 0.0 2e-93 313.1 0.0 1.9 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ICMT PF04140.9 EDN11332.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1769 PF08588.5 EDN11333.1 - 4.6e-28 96.9 1.1 6.8e-28 96.3 0.0 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1769) IncA PF04156.9 EDN11334.1 - 0.0022 17.6 57.0 0.025 14.1 3.1 5.2 3 1 2 5 5 5 3 IncA protein Sfi1_C PF10638.4 EDN11334.1 - 0.062 13.7 0.2 0.062 13.7 0.1 3.8 5 0 0 5 5 5 0 Spindle body associated protein C-terminus LPP PF04728.8 EDN11334.1 - 0.22 11.3 9.0 0.63 9.8 0.2 4.2 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Surfac_D-trimer PF09006.6 EDN11334.1 - 0.68 9.7 4.3 4 7.2 0.0 3.6 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation Reo_sigmaC PF04582.7 EDN11334.1 - 2.1 7.4 21.7 0.59 9.2 6.0 2.9 2 1 1 3 3 3 0 Reovirus sigma C capsid protein SRRM_C PF15230.1 EDN11335.1 - 2.9 8.0 6.4 0.93 9.6 1.9 1.9 1 1 1 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus ECH PF00378.15 EDN11336.1 - 6.5e-20 71.2 0.0 8e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EDN11336.1 - 0.053 13.2 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 PPDK_N PF01326.14 EDN11336.1 - 0.13 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain DUF3506 PF12014.3 EDN11337.1 - 5.4e-52 175.1 0.0 1e-51 174.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 EDN11337.1 - 9.1e-08 31.7 0.4 2.2e-07 30.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDN11337.1 - 9.9e-05 21.8 0.4 0.00021 20.8 0.3 1.6 1 0 0 1 1 1 1 F-box domain FAD_binding_3 PF01494.14 EDN11339.1 - 9.6e-17 61.0 0.0 8.8e-16 57.8 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EDN11339.1 - 0.00033 21.0 0.0 0.0044 17.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDN11339.1 - 0.00037 20.4 0.0 0.00096 19.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDN11339.1 - 0.0016 17.3 0.0 0.013 14.4 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EDN11339.1 - 0.019 13.4 0.0 0.028 12.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 EDN11339.1 - 0.021 14.7 0.0 0.056 13.3 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDN11339.1 - 0.034 13.2 0.7 0.34 9.9 0.1 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.5 EDN11339.1 - 0.068 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase GIDA PF01134.17 EDN11339.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Peptidase_M24 PF00557.19 EDN11340.1 - 2.5e-45 154.6 0.0 3.1e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EDN11340.1 - 0.00058 19.6 3.6 0.00058 19.6 2.5 2.2 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 EDN11340.1 - 0.76 9.4 3.6 2 8.1 2.5 1.8 1 0 0 1 1 1 0 HIT zinc finger MFS_1 PF07690.11 EDN11341.1 - 6.8e-37 126.9 42.6 3.3e-36 124.7 28.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDN11341.1 - 1.8e-13 49.9 8.8 1.8e-13 49.9 6.1 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter ZZ PF00569.12 EDN11342.1 - 1.4e-11 43.6 4.8 2.6e-11 42.8 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 EDN11342.1 - 2.8e-11 41.8 5.6 3e-05 22.9 0.4 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EDN11342.1 - 5.7e-10 39.1 4.2 7.8e-10 38.7 1.9 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EDN11342.1 - 1.5e-08 33.8 3.4 0.0011 18.6 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EDN11342.1 - 1.3e-05 24.7 6.8 0.01 15.4 0.3 3.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EDN11342.1 - 0.0026 17.0 3.6 0.14 11.5 0.2 2.9 2 0 0 2 2 2 2 EF hand WD40 PF00400.27 EDN11343.1 - 1e-38 129.8 10.7 2.6e-10 39.7 0.3 7.6 7 1 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EDN11343.1 - 5.9e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 PQQ-like domain Cornichon PF03311.9 EDN11344.1 - 3.4e-48 162.9 12.9 3.9e-48 162.8 8.9 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M50 PF02163.17 EDN11344.1 - 6.7 5.6 6.2 8.8 5.2 4.3 1.2 1 0 0 1 1 1 0 Peptidase family M50 MFS_1 PF07690.11 EDN11345.1 - 4.2e-08 32.2 3.8 5.7e-08 31.8 2.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Myc_target_1 PF15179.1 EDN11345.1 - 0.2 11.2 1.0 0.31 10.5 0.7 1.2 1 0 0 1 1 1 0 Myc target protein 1 NmrA PF05368.8 EDN11347.1 - 1.1e-22 80.4 0.0 1.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EDN11347.1 - 6.8e-12 45.7 0.1 1.1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDN11347.1 - 0.002 17.5 0.1 0.0035 16.8 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 EDN11347.1 - 0.0096 15.7 0.0 0.14 11.9 0.0 2.5 3 0 0 3 3 3 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EDN11347.1 - 0.016 13.9 0.4 0.058 12.0 0.3 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ABC2_membrane PF01061.19 EDN11349.1 - 8.7e-36 123.0 20.6 2.5e-35 121.5 14.3 1.9 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EDN11349.1 - 1.2e-24 87.1 0.5 2.3e-24 86.2 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EDN11349.1 - 2.3e-08 34.3 0.0 2.4e-07 31.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EDN11349.1 - 4.4e-07 29.2 22.2 4.4e-07 29.2 15.4 1.9 2 1 1 3 3 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 EDN11349.1 - 0.0068 15.8 0.0 0.073 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EDN11349.1 - 0.0086 15.1 0.0 3 6.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.1 EDN11349.1 - 0.0091 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain EGF_2 PF07974.8 EDN11349.1 - 0.011 15.8 10.5 0.011 15.8 7.3 3.0 3 0 0 3 3 2 0 EGF-like domain AAA_14 PF13173.1 EDN11349.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EDN11349.1 - 0.019 14.5 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 EDN11349.1 - 0.022 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 EDN11349.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase ATP-synt_ab PF00006.20 EDN11349.1 - 0.03 13.8 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 EDN11349.1 - 0.031 13.4 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDN11349.1 - 0.045 13.8 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EDN11349.1 - 0.055 14.2 0.0 0.12 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EDN11349.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDN11349.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EDN11349.1 - 0.15 12.3 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDN11349.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.19 EDN11349.1 - 0.4 10.6 22.9 2.8 7.9 6.3 2.6 1 1 1 2 2 2 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 EDN11349.1 - 3.9 7.7 27.0 0.13 12.4 2.7 4.1 4 0 0 4 4 3 0 Human growth factor-like EGF Aminotran_1_2 PF00155.16 EDN11350.1 - 0.019 13.9 0.0 2.9 6.7 0.0 2.1 1 1 1 2 2 2 0 Aminotransferase class I and II AMP-binding PF00501.23 EDN11351.1 - 7.4e-70 235.4 0.0 9.1e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDN11351.1 - 1.1e-08 35.9 0.0 2.3e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2614 PF11023.3 EDN11351.1 - 0.17 11.6 0.6 1 9.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) Lyase_1 PF00206.15 EDN11352.1 - 1.5e-87 293.6 0.0 2e-87 293.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EDN11352.1 - 4.1e-27 94.0 0.0 9e-27 92.9 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF1451 PF07295.6 EDN11352.1 - 0.16 11.7 0.0 0.72 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) Sulfatase PF00884.18 EDN11353.1 - 1.3e-09 37.7 0.1 2.1e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EDN11353.1 - 9.6e-05 21.8 0.1 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EDN11354.1 - 0.045 12.9 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Sulfatase DDE_1 PF03184.14 EDN11355.1 - 4.1e-36 124.1 0.0 7.8e-36 123.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN11355.1 - 2.3e-05 24.1 0.0 7.4e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EDN11355.1 - 0.0067 15.9 0.6 0.0067 15.9 0.4 2.1 2 0 0 2 2 2 1 helix-turn-helix, Psq domain Pox_VP8_L4R PF04498.7 EDN11355.1 - 0.069 12.4 0.0 4.2 6.6 0.0 2.7 2 1 1 3 3 3 0 Poxvirus nucleic acid binding protein VP8/L4R DUF2229 PF09989.4 EDN11355.1 - 0.98 8.8 6.4 5.7 6.3 4.1 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) TraG_N PF07916.6 EDN11355.1 - 1.1 7.6 3.8 1.6 7.0 2.7 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Borrelia_P83 PF05262.6 EDN11355.1 - 1.4 7.0 20.1 2.3 6.3 14.0 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Polyketide_cyc PF03364.15 EDN11358.1 - 2.9e-21 75.8 0.0 4.2e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EDN11358.1 - 0.002 18.2 0.8 0.028 14.6 0.5 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Sod_Fe_C PF02777.13 EDN11359.1 - 1.7e-15 56.7 0.0 2e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain TMEM154 PF15102.1 EDN11360.1 - 3.1e-05 23.7 0.1 5e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family Glycophorin_A PF01102.13 EDN11360.1 - 0.00044 19.9 1.0 0.00094 18.9 0.7 1.5 1 0 0 1 1 1 1 Glycophorin A Sarcoglycan_2 PF05510.8 EDN11360.1 - 0.032 12.5 0.0 0.043 12.1 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon PIG-S PF10510.4 EDN11361.1 - 4.7e-173 576.5 1.9 5.8e-173 576.2 1.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein FimP PF09766.4 EDN11362.1 - 1.3e-23 83.6 9.6 1.3e-23 83.6 6.7 1.3 2 0 0 2 2 2 1 Fms-interacting protein DUF4200 PF13863.1 EDN11362.1 - 0.0048 16.8 10.9 0.54 10.2 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) K-box PF01486.12 EDN11362.1 - 0.04 13.7 0.1 0.04 13.7 0.1 2.9 2 1 1 3 3 3 0 K-box region DUF972 PF06156.8 EDN11362.1 - 0.32 11.3 6.0 2.2 8.6 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Flagellin_N PF00669.15 EDN11362.1 - 0.36 10.6 3.2 0.33 10.7 0.6 1.9 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DivIC PF04977.10 EDN11362.1 - 2 7.9 9.4 4.9 6.7 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator Pinin_SDK_memA PF04696.8 EDN11362.1 - 2.3 7.8 8.9 1.1 8.8 3.1 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF349 PF03993.7 EDN11362.1 - 2.7 8.1 9.9 0.31 11.2 3.9 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF1003 PF06210.6 EDN11362.1 - 4.6 7.2 7.0 4.1 7.3 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1003) HlyIII PF03006.15 EDN11363.1 - 2.6e-57 193.7 20.1 3.2e-57 193.4 14.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.8 EDN11363.1 - 0.56 10.0 5.4 0.12 12.1 1.1 1.9 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) YfhO PF09586.5 EDN11363.1 - 1.1 7.2 11.0 1.5 6.7 7.6 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Fungal_trans PF04082.13 EDN11364.1 - 1.4e-32 112.6 1.0 2.1e-32 112.0 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 EDN11364.1 - 0.0015 18.3 0.0 0.0039 17.1 0.0 1.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain Glyco_hydro_44 PF12891.2 EDN11364.1 - 0.11 11.9 0.1 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 Glycoside hydrolase family 44 Sugar_tr PF00083.19 EDN11365.1 - 1.1e-90 304.3 24.6 2.7e-90 303.1 17.1 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDN11365.1 - 5.8e-17 61.4 47.2 3e-12 45.9 11.9 2.6 1 1 0 2 2 2 2 Major Facilitator Superfamily Methyltransf_12 PF08242.7 EDN11366.1 - 6.6e-15 55.4 0.0 1.6e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN11366.1 - 9e-11 42.1 0.0 1.8e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDN11366.1 - 6.1e-10 39.6 0.0 1e-09 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN11366.1 - 2.3e-09 36.9 0.0 3.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN11366.1 - 4.3e-09 36.6 0.0 7.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDN11366.1 - 4e-08 33.1 0.0 6.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDN11366.1 - 4.3e-05 23.5 0.0 0.0001 22.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EDN11366.1 - 9e-05 21.5 0.0 0.00022 20.2 0.0 1.6 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.13 EDN11366.1 - 9.5e-05 21.6 0.0 0.00013 21.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 EDN11366.1 - 0.0001 23.0 0.0 0.00026 21.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EDN11366.1 - 0.0038 16.6 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.7 EDN11366.1 - 0.021 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Diphthamide_syn PF01866.12 EDN11368.1 - 4.6e-49 167.3 0.0 3.2e-48 164.5 0.0 2.1 2 1 0 2 2 2 1 Putative diphthamide synthesis protein DDE_1 PF03184.14 EDN11369.1 - 2.4e-43 147.8 0.0 4.1e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN11369.1 - 2.4e-09 36.5 0.1 6e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN11369.1 - 1.4e-08 34.4 0.0 4.1e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.1 EDN11369.1 - 0.0035 17.3 0.6 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain NUMOD1 PF07453.8 EDN11369.1 - 0.044 13.6 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 NUMOD1 domain WD40 PF00400.27 EDN11370.1 - 0.0015 18.3 5.8 0.2 11.6 0.0 4.8 5 1 0 5 5 5 1 WD domain, G-beta repeat SPT6_acidic PF14632.1 EDN11370.1 - 1.5 9.0 18.2 0.34 11.0 10.3 1.6 2 0 0 2 2 2 0 Acidic N-terminal SPT6 CDC45 PF02724.9 EDN11370.1 - 2.8 5.8 5.4 3.8 5.4 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein p450 PF00067.17 EDN11371.1 - 1.5e-50 172.0 0.0 1.9e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BIV_Env PF05858.7 EDN11371.1 - 0.01 13.8 0.0 1 7.2 0.0 2.1 2 0 0 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) DIE2_ALG10 PF04922.7 EDN11372.1 - 1.6e-71 241.3 19.9 3e-71 240.4 11.8 2.8 2 1 0 2 2 2 1 DIE2/ALG10 family Sld5 PF05916.6 EDN11373.1 - 5e-29 100.7 0.0 8e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein CUE PF02845.11 EDN11374.1 - 4.6e-12 45.1 0.0 8.8e-12 44.2 0.0 1.5 1 0 0 1 1 1 1 CUE domain Methyltransf_23 PF13489.1 EDN11375.1 - 3.9e-09 36.4 0.0 6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDN11375.1 - 2.7e-07 31.0 0.0 5.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDN11375.1 - 5.4e-06 26.0 0.0 2.2e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDN11375.1 - 5.2e-05 23.6 0.0 9.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EDN11375.1 - 0.00016 21.0 0.0 0.00024 20.4 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.2 EDN11375.1 - 0.00028 21.4 0.0 0.0015 19.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDN11375.1 - 0.001 19.3 0.0 0.0024 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain SMC_N PF02463.14 EDN11376.1 - 2.1e-70 236.3 0.0 5.7e-70 234.9 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDN11376.1 - 2.2e-22 79.2 1.0 1.1e-21 76.9 0.2 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EDN11376.1 - 5.6e-11 42.9 14.2 1.5e-05 25.1 0.0 4.1 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EDN11376.1 - 0.00076 18.9 0.1 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.2 EDN11376.1 - 0.00086 18.6 19.4 0.00086 18.6 13.4 7.1 2 2 5 7 7 7 2 Mechanosensitive ion channel porin domain ABC_tran PF00005.22 EDN11376.1 - 0.061 13.6 0.1 0.061 13.6 0.0 5.4 4 2 0 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 EDN11376.1 - 2.4 7.2 29.4 2.7 7.0 6.0 5.6 3 2 5 8 8 8 0 Reovirus sigma C capsid protein GDI PF00996.13 EDN11377.1 - 2.4e-176 586.3 0.0 3.2e-176 585.9 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EDN11377.1 - 0.13 12.2 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.8 EDN11378.1 - 4.9e-21 74.4 0.0 7.4e-21 73.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) NOT2_3_5 PF04153.13 EDN11380.1 - 6.8e-34 116.6 0.1 6.8e-34 116.6 0.1 2.2 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family 4HBT PF03061.17 EDN11381.1 - 5.7e-11 42.3 0.3 7.7e-11 41.9 0.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Neuromodulin_N PF10580.4 EDN11382.1 - 0.11 12.1 0.5 0.32 10.6 0.3 1.7 1 0 0 1 1 1 0 Gap junction protein N-terminal region ORC4_C PF14629.1 EDN11383.1 - 3.2e-58 196.4 0.0 4.8e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EDN11383.1 - 1.6e-17 64.0 0.3 6.8e-17 62.0 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EDN11383.1 - 6.4e-07 29.6 0.0 2.8e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDN11383.1 - 1.5e-05 25.1 0.0 3.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EDN11383.1 - 5.7e-05 22.9 0.0 8.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase DUF815 PF05673.8 EDN11383.1 - 7.9e-05 21.7 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.7 EDN11383.1 - 0.00019 21.1 0.0 0.00083 19.0 0.0 2.1 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EDN11383.1 - 0.011 14.7 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.1 EDN11383.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain G-alpha PF00503.15 EDN11383.1 - 0.018 13.7 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.1 EDN11383.1 - 0.04 13.4 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MotB_plug PF13677.1 EDN11383.1 - 0.078 12.3 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB FtsK_SpoIIIE PF01580.13 EDN11383.1 - 0.089 12.2 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 EDN11383.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain ThiS-like PF14453.1 EDN11383.1 - 0.2 11.5 0.3 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 ThiS-like ubiquitin RGS PF00615.14 EDN11385.1 - 4.9e-32 110.4 0.0 1e-31 109.4 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 EDN11385.1 - 1.9e-23 81.9 0.0 6.2e-21 73.9 0.0 2.4 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Lipoprotein_9 PF03180.9 EDN11385.1 - 0.12 11.2 0.0 0.25 10.1 0.0 1.5 1 0 0 1 1 1 0 NLPA lipoprotein CDC73 PF05179.9 EDN11386.1 - 2.6e-38 131.9 0.4 1.8e-36 125.8 0.3 2.3 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family HNH_2 PF13391.1 EDN11387.1 - 1.6e-06 27.7 0.0 4.7e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 HNH endonuclease SET PF00856.23 EDN11388.1 - 1.2e-05 25.7 0.1 1.2e-05 25.7 0.0 4.0 4 1 0 4 4 4 1 SET domain PHD PF00628.24 EDN11388.1 - 6.9e-05 22.4 10.3 0.00015 21.4 7.1 1.6 1 0 0 1 1 1 1 PHD-finger ArfGap PF01412.13 EDN11389.1 - 4.7e-07 29.6 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Glyco_transf_22 PF03901.12 EDN11390.1 - 2.7e-76 257.2 23.8 3.8e-76 256.7 16.5 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aminotran_3 PF00202.16 EDN11391.1 - 2.2e-103 345.6 0.0 2.8e-103 345.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EDN11391.1 - 0.044 12.7 0.0 0.088 11.7 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II ABC_membrane PF00664.18 EDN11392.1 - 7.7e-49 166.5 37.8 2e-26 93.0 13.8 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EDN11392.1 - 1.5e-45 154.8 0.1 5.3e-26 91.5 0.0 3.3 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EDN11392.1 - 2.5e-06 27.7 0.1 1 9.2 0.0 4.0 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EDN11392.1 - 7.1e-06 25.9 0.0 0.16 11.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 EDN11392.1 - 9.4e-06 26.4 0.1 0.19 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EDN11392.1 - 2.2e-05 23.7 0.2 0.037 13.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDN11392.1 - 2.4e-05 24.3 2.4 0.055 13.4 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EDN11392.1 - 4.3e-05 23.9 0.2 0.071 13.6 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein Zeta_toxin PF06414.7 EDN11392.1 - 4.4e-05 22.6 0.0 0.087 11.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.1 EDN11392.1 - 4.5e-05 22.8 1.0 0.26 10.8 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EDN11392.1 - 5.2e-05 22.5 2.2 0.19 10.8 0.7 3.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.18 EDN11392.1 - 0.00023 21.0 0.7 0.0037 17.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.13 EDN11392.1 - 0.00026 20.5 0.2 0.038 13.4 0.1 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EDN11392.1 - 0.00039 20.7 0.6 1.6 9.0 0.4 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EDN11392.1 - 0.00098 18.6 0.1 0.85 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain ArgK PF03308.11 EDN11392.1 - 0.0021 16.8 2.1 1 8.1 0.2 2.3 2 0 0 2 2 2 2 ArgK protein DUF87 PF01935.12 EDN11392.1 - 0.0024 17.7 3.6 0.0076 16.0 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_25 PF13481.1 EDN11392.1 - 0.0047 16.3 0.1 3.8 6.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EDN11392.1 - 0.026 14.7 0.1 8.5 6.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.1 EDN11392.1 - 0.03 14.6 6.0 1.5 9.1 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EDN11392.1 - 0.031 14.4 4.8 7.3 6.7 0.0 3.5 3 1 0 3 3 2 0 AAA domain TrwB_AAD_bind PF10412.4 EDN11392.1 - 0.043 12.4 1.7 3.2 6.2 0.3 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 EDN11392.1 - 0.047 13.2 1.4 2.1 7.7 0.1 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.24 EDN11392.1 - 0.058 13.5 0.1 0.64 10.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EDN11392.1 - 0.082 12.8 0.0 0.082 12.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain FAM70 PF14967.1 EDN11392.1 - 0.14 11.2 0.9 0.33 10.1 0.6 1.5 1 0 0 1 1 1 0 FAM70 protein MobB PF03205.9 EDN11392.1 - 0.17 11.6 1.0 13 5.4 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EDN11392.1 - 0.21 11.0 2.6 17 4.7 0.3 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 EDN11392.1 - 0.23 10.4 0.0 1 8.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 EDN11392.1 - 0.34 10.3 1.3 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 EDN11392.1 - 0.54 9.0 2.6 1.6 7.5 0.5 2.2 2 0 0 2 2 2 0 NB-ARC domain DUF3435 PF11917.3 EDN11393.1 - 1e-154 515.3 0.1 1e-154 515.3 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) Ribosomal_L6e PF01159.14 EDN11393.1 - 0.042 14.0 3.9 0.14 12.4 2.7 1.8 1 0 0 1 1 1 0 Ribosomal protein L6e BSP_II PF05432.6 EDN11393.1 - 0.19 10.9 20.6 0.3 10.3 14.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 EDN11393.1 - 0.24 9.4 8.7 0.33 8.9 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.9 EDN11393.1 - 0.5 9.8 14.4 1.1 8.7 10.0 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein KOG2701 PF09762.4 EDN11393.1 - 0.63 10.0 5.2 7.1 6.6 0.0 2.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein (DUF2037) zf-C2H2 PF00096.21 EDN11393.1 - 0.75 10.2 12.2 6.4 7.3 1.5 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type Daxx PF03344.10 EDN11393.1 - 1.5 7.1 20.6 2.7 6.3 14.3 1.3 1 0 0 1 1 1 0 Daxx Family RRN3 PF05327.6 EDN11393.1 - 1.6 6.7 8.6 1.7 6.6 4.2 2.0 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 zf-C2H2_4 PF13894.1 EDN11393.1 - 2.1 8.8 11.8 2.4 8.7 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Radial_spoke PF04712.7 EDN11393.1 - 4.6 5.8 15.5 8.3 5.0 10.7 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein Nop14 PF04147.7 EDN11393.1 - 7.3 4.3 24.0 11 3.7 16.6 1.2 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.20 EDN11395.1 - 7.3e-12 44.9 2.1 1e-11 44.4 1.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN11395.1 - 1.1e-07 31.1 2.5 1.8e-07 30.5 1.7 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Nucleocapsid-N PF11030.3 EDN11395.1 - 0.066 13.0 0.3 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Nucleocapsid protein N MIP-T3 PF10243.4 EDN11396.1 - 0.0019 16.7 33.4 0.0019 16.7 23.2 2.8 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 HNH_2 PF13391.1 EDN11397.1 - 4.6e-13 48.7 0.1 1.2e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease APH PF01636.18 EDN11397.1 - 6.1e-08 32.6 0.1 3.3e-07 30.2 0.2 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family KNOX2 PF03791.8 EDN11397.1 - 0.021 14.0 0.3 0.048 12.9 0.2 1.5 1 0 0 1 1 1 0 KNOX2 domain Pkinase PF00069.20 EDN11401.1 - 1.7e-07 30.7 0.0 2.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EDN11401.1 - 0.00014 21.6 0.3 0.0013 18.5 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EDN11401.1 - 0.00022 20.3 0.0 0.00035 19.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EDN11401.1 - 0.0048 16.4 0.0 0.0095 15.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase ADP_ribosyl_GH PF03747.9 EDN11402.1 - 3.1e-54 184.7 0.1 4.5e-54 184.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase SHR3_chaperone PF08229.6 EDN11405.1 - 8.1e-82 272.9 0.0 9e-82 272.7 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Claudin_2 PF13903.1 EDN11405.1 - 0.079 12.6 0.1 0.29 10.7 0.1 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2681 PF10883.3 EDN11405.1 - 0.091 12.9 0.6 0.19 11.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) HlyIII PF03006.15 EDN11405.1 - 2.1 7.7 5.8 0.25 10.7 1.3 1.4 2 0 0 2 2 2 0 Haemolysin-III related Tyrosinase PF00264.15 EDN11406.1 - 2.8e-57 194.4 0.6 4.4e-57 193.7 0.4 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Gal-bind_lectin PF00337.17 EDN11406.1 - 1.6e-07 30.7 0.0 3.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Galactoside-binding lectin Arrestin_N PF00339.24 EDN11407.1 - 1.7e-16 60.3 0.0 1.2e-15 57.6 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Flavoprotein PF02441.14 EDN11409.1 - 3.9e-39 133.2 0.1 5.3e-39 132.8 0.1 1.2 1 0 0 1 1 1 1 Flavoprotein Mnd1 PF03962.10 EDN11411.1 - 8.4e-44 149.4 1.6 1e-43 149.1 1.1 1.1 1 0 0 1 1 1 1 Mnd1 family DsrD PF08679.6 EDN11411.1 - 0.00061 19.7 0.5 0.0012 18.8 0.0 1.8 2 0 0 2 2 2 1 Dissimilatory sulfite reductase D (DsrD) Penicillinase_R PF03965.11 EDN11411.1 - 0.016 15.2 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 Penicillinase repressor Myosin_HC-like PF07058.6 EDN11411.1 - 6.1 5.8 12.0 3.2 6.7 3.1 2.1 1 1 1 2 2 2 0 Myosin II heavy chain-like UAF_Rrn10 PF05234.6 EDN11412.1 - 0.00012 22.0 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 UAF complex subunit Rrn10 DDE_1 PF03184.14 EDN11413.1 - 2.1e-51 174.1 0.0 6.8e-51 172.4 0.0 1.9 3 0 0 3 3 3 1 DDE superfamily endonuclease HTH_psq PF05225.11 EDN11413.1 - 3.7e-09 35.9 0.1 8.5e-09 34.8 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN11413.1 - 1.7e-08 34.1 0.1 6e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.1 EDN11413.1 - 0.0054 16.7 0.1 0.017 15.1 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain zf-CCHC_4 PF14392.1 EDN11413.1 - 0.04 13.5 0.5 0.04 13.5 0.3 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 EDN11413.1 - 0.05 13.2 0.4 0.45 10.2 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle NUMOD1 PF07453.8 EDN11413.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 NUMOD1 domain zf-CCHC PF00098.18 EDN11413.1 - 0.27 11.2 1.0 0.48 10.4 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle DALR_1 PF05746.10 EDN11414.1 - 0.24 11.3 2.9 0.29 11.0 2.0 1.2 1 0 0 1 1 1 0 DALR anticodon binding domain DUF4544 PF15077.1 EDN11414.1 - 0.31 10.5 1.8 0.36 10.2 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) KBP_C PF12309.3 EDN11414.1 - 0.95 8.3 11.4 1 8.2 7.9 1.0 1 0 0 1 1 1 0 KIF-1 binding protein C terminal DUF2407_C PF13373.1 EDN11414.1 - 1.2 9.0 6.2 1.5 8.7 4.3 1.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain Bestrophin PF01062.16 EDN11414.1 - 1.5 7.6 4.5 1.8 7.4 3.1 1.0 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel AIF_C PF14721.1 EDN11414.1 - 3.8 7.7 7.6 38 4.5 5.3 2.0 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term HTH_psq PF05225.11 EDN11415.1 - 0.00066 19.1 0.3 0.0022 17.5 0.2 1.9 1 1 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EDN11415.1 - 0.0029 17.3 0.0 0.015 15.0 0.0 2.1 1 1 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.1 EDN11415.1 - 0.0044 16.9 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EDN11415.1 - 0.026 14.1 0.0 0.088 12.4 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.1 EDN11415.1 - 0.038 14.1 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix NUMOD1 PF07453.8 EDN11415.1 - 0.14 12.0 0.1 0.14 12.0 0.1 2.4 3 0 0 3 3 3 0 NUMOD1 domain WD40 PF00400.27 EDN11416.1 - 3.9e-23 80.4 20.3 2.4e-07 30.3 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF4219 PF13961.1 EDN11417.1 - 0.0035 16.7 0.3 0.0058 16.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Mito_fiss_reg PF05308.6 EDN11417.1 - 0.77 9.0 16.3 0.32 10.3 4.3 2.2 1 1 1 2 2 2 0 Mitochondrial fission regulator Chromo PF00385.19 EDN11418.1 - 4.3e-14 51.9 0.7 1.2e-13 50.5 0.5 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EDN11418.1 - 0.0049 16.5 0.3 0.013 15.1 0.2 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF624 PF04854.9 EDN11419.1 - 0.2 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF624 RVT_1 PF00078.22 EDN11420.1 - 1.7e-35 122.3 0.0 2.6e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDN11420.1 - 1.1e-14 54.8 0.0 2.6e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EDN11420.1 - 1.3e-13 50.6 0.0 2.7e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase CEP44 PF15007.1 EDN11421.1 - 0.11 12.2 0.2 0.13 11.9 0.2 1.1 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 MHC_II_beta PF00969.14 EDN11422.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain Pkinase PF00069.20 EDN11424.1 - 5.4e-07 29.0 0.0 1.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EDN11424.1 - 0.00025 20.1 0.0 0.00049 19.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDN11424.1 - 0.005 16.5 0.1 0.02 14.6 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family STAT_int PF02865.12 EDN11425.1 - 0.016 15.1 1.9 0.052 13.5 0.0 2.2 1 1 1 2 2 2 0 STAT protein, protein interaction domain DDHD PF02862.12 EDN11425.1 - 0.1 12.3 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 DDHD domain Exonuc_VII_S PF02609.11 EDN11425.1 - 0.96 9.2 5.1 5.3 6.8 1.0 2.4 2 0 0 2 2 2 0 Exonuclease VII small subunit Fungal_trans_2 PF11951.3 EDN11427.1 - 4.3e-83 279.0 0.0 5.7e-83 278.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDN11427.1 - 0.00012 21.8 9.5 0.00025 20.8 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop14 PF04147.7 EDN11428.1 - 0.0055 14.6 9.3 0.0056 14.6 6.5 1.1 1 0 0 1 1 1 1 Nop14-like family Sigma70_ner PF04546.8 EDN11428.1 - 0.0096 15.5 8.0 0.015 14.9 5.6 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EDN11428.1 - 0.034 13.6 16.6 0.069 12.6 11.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EDN11428.1 - 0.041 11.9 6.9 0.043 11.8 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein RNase_H2_suC PF08615.6 EDN11428.1 - 0.054 13.3 0.6 0.15 11.8 0.4 1.9 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Daxx PF03344.10 EDN11428.1 - 0.089 11.2 9.1 0.1 11.1 6.3 1.1 1 0 0 1 1 1 0 Daxx Family eIF-3c_N PF05470.7 EDN11428.1 - 0.16 10.0 3.3 0.19 9.7 2.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Tom22 PF04281.8 EDN11428.1 - 0.17 11.4 7.1 0.018 14.5 1.5 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 NOA36 PF06524.7 EDN11428.1 - 0.23 10.6 18.4 0.35 10.0 12.8 1.2 1 0 0 1 1 1 0 NOA36 protein SGT1 PF07093.6 EDN11428.1 - 0.25 9.6 7.5 0.31 9.3 5.2 1.1 1 0 0 1 1 1 0 SGT1 protein RRN3 PF05327.6 EDN11428.1 - 0.54 8.2 5.9 0.59 8.1 4.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.7 EDN11428.1 - 0.58 9.3 10.8 0.7 9.1 7.5 1.2 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 EDN11428.1 - 1.5 7.5 32.8 2.1 6.9 22.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.6 EDN11428.1 - 2 8.1 12.1 3.7 7.3 8.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal GCIP PF13324.1 EDN11428.1 - 4.2 6.5 7.6 5.9 6.0 5.3 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting SAM_2 PF07647.12 EDN11430.1 - 1.9e-10 40.4 0.0 3.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EDN11430.1 - 1.2e-08 34.9 0.0 2.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EDN11430.1 - 1e-05 25.6 0.0 2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 PH domain Ste50p-SAM PF09235.5 EDN11430.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PH_9 PF15410.1 EDN11430.1 - 0.033 14.3 0.4 0.091 12.9 0.3 1.7 1 1 0 1 1 1 0 Pleckstrin homology domain APG5 PF04106.7 EDN11431.1 - 7.1e-70 234.5 0.0 8.5e-70 234.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Tyr-DNA_phospho PF06087.7 EDN11432.1 - 2.1e-142 474.9 0.0 7.1e-142 473.1 0.0 1.7 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EDN11432.1 - 0.00067 19.3 0.0 0.31 10.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain QCR10 PF09796.4 EDN11433.1 - 1e-28 98.7 0.5 1.4e-28 98.3 0.3 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Chromo PF00385.19 EDN11434.1 - 1.1e-16 60.1 4.6 3.2e-16 58.7 3.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EDN11434.1 - 0.15 11.7 2.0 0.42 10.3 1.4 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Pkinase PF00069.20 EDN11436.1 - 9.1e-31 106.9 0.0 4.1e-30 104.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDN11436.1 - 8.4e-10 38.1 0.0 5.2e-07 28.9 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EDN11436.1 - 9e-05 21.5 0.0 0.0065 15.4 0.0 2.6 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EDN11436.1 - 0.0026 17.5 0.1 0.1 12.3 0.1 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family RVT_2 PF07727.9 EDN11437.1 - 8.2e-59 198.5 0.0 1.2e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_1 PF03184.14 EDN11438.1 - 4.5e-36 124.0 0.0 7.8e-36 123.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDN11438.1 - 2.7e-14 52.7 0.4 3.2e-13 49.2 0.0 3.0 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain EST1_DNA_bind PF10373.4 EDN11438.1 - 0.0011 18.2 0.0 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain PFL PF02901.10 EDN11438.1 - 0.028 12.8 0.7 0.046 12.1 0.5 1.2 1 0 0 1 1 1 0 Pyruvate formate lyase Mpp10 PF04006.7 EDN11439.1 - 2.4e-76 257.4 6.0 3.6e-76 256.8 4.1 1.2 1 0 0 1 1 1 1 Mpp10 protein Exo_endo_phos_2 PF14529.1 EDN11443.1 - 1.6e-14 53.4 0.0 3.4e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EDN11444.1 - 1.1e-24 86.9 0.0 1.3e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3505 PF12013.3 EDN11446.1 - 6.7e-16 58.4 0.3 7.8e-15 55.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) Helicase_C PF00271.26 EDN11447.1 - 1.2e-09 37.9 0.1 2.9e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Retrotrans_gag PF03732.12 EDN11448.1 - 3.1e-05 23.9 2.9 3.1e-05 23.9 2.0 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein HD_4 PF13328.1 EDN11448.1 - 0.063 12.9 0.1 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 HD domain