# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Epimerase PF01370.21 EPE24091.1 - 2.6e-12 46.8 0.0 7.5e-12 45.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPE24091.1 - 2.1e-09 37.5 0.0 2.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPE24091.1 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EPE24091.1 - 4.7e-05 22.5 0.0 8.6e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AlaDh_PNT_C PF01262.21 EPE24091.1 - 0.00026 20.4 0.0 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GDP_Man_Dehyd PF16363.5 EPE24091.1 - 0.00027 20.5 0.0 0.066 12.6 0.1 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 EPE24091.1 - 0.00048 20.4 0.1 0.001 19.3 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.17 EPE24091.1 - 0.00096 18.3 0.0 0.031 13.4 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_2 PF03446.15 EPE24091.1 - 0.0038 17.4 0.0 0.0058 16.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_4 PF07993.12 EPE24091.1 - 0.0082 15.3 0.2 0.034 13.3 0.2 2.1 1 1 1 2 2 2 1 Male sterility protein Shikimate_DH PF01488.20 EPE24091.1 - 0.017 15.2 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EPE24091.1 - 0.026 15.1 0.0 0.066 13.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 EPE24091.1 - 0.028 13.9 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus F420_oxidored PF03807.17 EPE24091.1 - 0.056 14.0 0.1 0.14 12.8 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sugar_tr PF00083.24 EPE24092.1 - 1.6e-97 327.2 28.6 1.9e-97 327.0 28.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE24092.1 - 3.9e-27 95.1 25.5 3.9e-27 95.1 25.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE24092.1 - 0.00049 18.6 1.7 0.00049 18.6 1.7 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3021 PF11457.8 EPE24092.1 - 0.0086 16.4 10.8 0.0086 16.4 10.8 3.3 2 2 1 3 3 3 1 Protein of unknown function (DUF3021) UPF0060 PF02694.15 EPE24092.1 - 0.092 13.0 0.2 0.092 13.0 0.2 2.8 4 0 0 4 4 4 0 Uncharacterised BCR, YnfA/UPF0060 family DUF3180 PF11377.8 EPE24092.1 - 8.3 6.6 11.0 0.2 11.8 1.4 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF3180) Glyco_hydro_31 PF01055.26 EPE24094.1 - 1.5e-108 363.8 0.2 2.1e-108 363.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EPE24094.1 - 1.7e-15 57.1 0.0 5e-15 55.6 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like p450 PF00067.22 EPE24095.1 - 8e-54 183.1 0.0 1.1e-53 182.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YlbE PF14003.6 EPE24095.1 - 0.062 13.8 0.0 0.39 11.2 0.0 2.3 2 0 0 2 2 2 0 YlbE-like protein Cellulase PF00150.18 EPE24096.1 - 7.9e-19 68.2 7.4 1.2e-18 67.6 7.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NUDIX PF00293.28 EPE24097.1 - 4.3e-09 36.5 0.0 8.8e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF3869 PF12985.7 EPE24097.1 - 0.14 12.5 0.1 0.23 11.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3869) Iso_dh PF00180.20 EPE24098.1 - 1.9e-85 287.1 0.0 2.2e-85 286.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Catalase PF00199.19 EPE24099.1 - 1.8e-175 583.7 0.0 2.3e-175 583.3 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EPE24099.1 - 1.5e-10 41.1 0.0 2.9e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Uricase PF01014.18 EPE24099.1 - 0.073 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Uricase Bac_rhodopsin PF01036.18 EPE24101.1 - 1.1e-36 126.5 21.7 1.1e-36 126.5 21.7 1.6 2 0 0 2 2 2 1 Bacteriorhodopsin-like protein DUF5516 PF17637.2 EPE24101.1 - 0.12 12.2 0.3 0.12 12.2 0.3 2.6 4 0 0 4 4 4 0 Family of unknown function (DUF5516) DUF809 PF05663.11 EPE24101.1 - 0.15 12.2 0.2 0.3 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF809) GMC_oxred_N PF00732.19 EPE24102.1 - 5.7e-48 163.8 0.0 9.2e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE24102.1 - 5.7e-30 104.7 0.0 3.1e-29 102.3 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EPE24102.1 - 0.013 15.7 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPE24102.1 - 0.016 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein HHH_5 PF14520.6 EPE24102.1 - 0.21 12.2 0.0 0.52 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Goodbye PF17109.5 EPE24106.1 - 0.032 14.7 0.1 0.18 12.3 0.0 2.3 2 1 0 2 2 2 0 fungal STAND N-terminal Goodbye domain AAA PF00004.29 EPE24107.1 - 3e-18 66.5 0.0 7e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE24107.1 - 4.6e-05 23.9 0.1 0.00081 19.8 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EPE24107.1 - 0.0012 19.4 0.2 0.017 15.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EPE24107.1 - 0.0021 18.0 0.0 0.0062 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF1308 PF07000.11 EPE24107.1 - 0.0024 17.8 0.1 0.0064 16.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) AAA_22 PF13401.6 EPE24107.1 - 0.03 14.6 1.5 0.11 12.8 0.3 2.5 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EPE24107.1 - 0.08 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain CPT PF07931.12 EPE24107.1 - 0.084 12.7 0.0 0.25 11.2 0.0 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 EPE24107.1 - 0.37 11.0 2.2 0.54 10.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.25 EPE24109.1 - 5.3e-22 78.4 0.0 1.5e-21 77.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE24109.1 - 2.6e-09 36.7 0.0 5.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPE24109.1 - 0.0011 19.0 0.2 0.02 14.9 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EPE24109.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family OPT PF03169.15 EPE24110.1 - 1.7e-205 684.3 33.4 2e-205 684.1 33.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Kdo PF06293.14 EPE24112.1 - 0.09 12.1 0.0 3.5 6.9 0.0 2.2 1 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Radial_spoke_3 PF06098.11 EPE24113.1 - 0.35 10.1 4.4 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Radial spoke protein 3 3Beta_HSD PF01073.19 EPE24114.1 - 1.7e-40 138.8 0.0 2.2e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPE24114.1 - 4e-27 95.2 0.0 5.2e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE24114.1 - 1e-13 51.4 0.0 1.8e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPE24114.1 - 5.6e-11 42.1 0.0 3.3e-07 29.7 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EPE24114.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain p450 PF00067.22 EPE24115.1 - 5.6e-34 117.7 0.0 7.4e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EPE24116.1 - 2e-36 125.7 45.6 1.5e-24 86.6 16.8 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE24116.1 - 2.9e-09 36.3 7.2 2.9e-09 36.3 7.2 3.1 2 2 1 3 3 3 1 Sugar (and other) transporter MctB PF11382.8 EPE24116.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Pam17 PF08566.10 EPE24116.1 - 0.44 10.4 3.7 1.4 8.8 0.1 2.9 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 UPF0114 PF03350.16 EPE24117.1 - 0.38 11.0 7.0 0.53 10.5 1.7 2.6 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 DHHC PF01529.20 EPE24119.1 - 0.41 10.8 5.1 0.18 11.9 2.0 1.9 1 1 1 2 2 2 0 DHHC palmitoyltransferase Peptidase_M50B PF13398.6 EPE24120.1 - 2e-59 200.6 16.8 2.4e-59 200.3 16.8 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 EPE24120.1 - 0.0079 15.5 0.1 0.016 14.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M50 Peptidase_M41 PF01434.18 EPE24120.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M41 Git3 PF11710.8 EPE24121.1 - 8e-11 42.1 9.3 1.2e-10 41.5 9.3 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_2 PF00002.24 EPE24121.1 - 8.3e-11 41.6 6.1 1.1e-10 41.3 6.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 EPE24121.1 - 1.6e-08 34.1 7.1 1.6e-08 34.1 7.1 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 EPE24121.1 - 1.4e-06 27.9 3.1 1.8e-06 27.5 3.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEMspv1-c74-12 PF11044.8 EPE24121.1 - 0.015 15.3 1.9 0.019 15.0 0.0 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Bac_GH3_C PF18034.1 EPE24121.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial Glycosyl hydrolase family 3 C-terminal domain TMEM190 PF15431.6 EPE24121.1 - 0.045 13.9 1.4 0.18 12.0 0.7 2.1 1 1 1 2 2 2 0 Transmembrane protein 190 Frizzled PF01534.17 EPE24121.1 - 0.36 9.8 9.5 0.82 8.7 1.2 2.1 1 1 1 2 2 2 0 Frizzled/Smoothened family membrane region Aspzincin_M35 PF14521.6 EPE24122.1 - 7e-08 33.1 0.0 1.7e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EPE24122.1 - 0.00031 20.4 0.4 0.00044 19.9 0.4 1.2 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M35 PF02102.15 EPE24122.1 - 0.072 11.9 0.2 0.099 11.5 0.2 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EPE24123.1 - 7.5e-06 26.5 0.1 1.8e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EPE24123.1 - 6e-05 22.7 3.4 0.00045 19.9 3.5 2.0 1 1 0 1 1 1 1 Putative peptidase family Peptidase_M35 PF02102.15 EPE24123.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EPE24124.1 - 0.096 13.2 0.1 0.18 12.4 0.1 1.5 1 1 0 1 1 1 0 Lysine-specific metallo-endopeptidase MGDG_synth PF06925.11 EPE24125.1 - 0.035 14.2 0.1 0.83 9.7 0.0 2.1 2 0 0 2 2 2 0 Monogalactosyldiacylglycerol (MGDG) synthase Abhydrolase_6 PF12697.7 EPE24126.1 - 6.6e-07 30.2 0.0 1e-06 29.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE24126.1 - 0.002 17.4 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE24126.1 - 0.06 13.0 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold NEMP PF10225.9 EPE24126.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 NEMP family AP3D1 PF06375.11 EPE24127.1 - 0.089 13.0 3.1 0.12 12.6 3.1 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 SPR1 PF15356.6 EPE24128.1 - 0.59 10.7 8.0 0.1 13.1 1.9 2.3 1 1 0 2 2 2 0 Psoriasis susceptibility locus 2 SKG6 PF08693.10 EPE24130.1 - 8.3e-06 25.1 0.4 2e-05 23.9 0.4 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4436 PF14494.6 EPE24131.1 - 0.17 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) Inositol_P PF00459.25 EPE24132.1 - 7.8e-62 209.3 0.0 9.2e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Alpha-amylase PF00128.24 EPE24133.1 - 2.2e-113 379.3 0.7 3.1e-113 378.8 0.0 1.5 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EPE24133.1 - 8.9e-05 22.5 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 EPE24133.1 - 0.0012 18.1 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain zf-C2H2 PF00096.26 EPE24136.1 - 0.48 11.0 5.1 4.4 7.9 0.0 3.3 3 1 0 3 3 3 0 Zinc finger, C2H2 type HET PF06985.11 EPE24137.1 - 1.4e-22 80.6 3.8 3.3e-22 79.4 3.8 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_zinc_N_2 PF13602.6 EPE24138.1 - 4.8e-26 92.4 0.1 8e-26 91.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPE24138.1 - 2.8e-18 66.1 0.2 5.3e-18 65.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DAGK_cat PF00781.24 EPE24139.1 - 1.3e-13 50.7 0.0 2.4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain TFB6 PF17110.5 EPE24140.1 - 0.015 15.1 0.0 0.69 9.6 0.0 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH TT_ORF1 PF02956.14 EPE24142.1 - 2.9 6.4 6.8 5.2 5.6 6.8 1.3 1 0 0 1 1 1 0 TT viral orf 1 DUF604 PF04646.12 EPE24143.1 - 2.7e-08 33.5 0.2 1.4e-07 31.2 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 EPE24143.1 - 0.035 13.5 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Fringe-like HET PF06985.11 EPE24144.1 - 5.9e-17 62.4 0.6 1.1e-16 61.5 0.6 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pirin PF02678.16 EPE24145.1 - 2e-24 85.6 1.5 6.4e-24 84.0 1.5 1.8 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 EPE24145.1 - 3e-05 23.7 1.0 0.0073 16.0 0.4 3.2 2 1 0 2 2 2 1 Cupin domain 2OG-FeII_Oxy PF03171.20 EPE24145.1 - 0.0056 17.2 0.1 0.012 16.1 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AraC_binding_2 PF14525.6 EPE24145.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 AraC-binding-like domain His_Phos_2 PF00328.22 EPE24147.1 - 1e-108 364.1 0.6 1.8e-108 363.3 0.6 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EPE24147.1 - 2.6e-36 123.7 0.0 6.3e-36 122.4 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EPE24147.1 - 1.8e-05 24.4 0.0 3.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.12 EPE24148.1 - 2.4e-82 275.9 0.0 3.4e-82 275.4 0.0 1.1 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EPE24148.1 - 5.1e-16 58.8 25.7 5.8e-06 26.9 0.9 10.2 10 0 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE24148.1 - 1.5e-15 57.3 0.0 7.3e-05 23.0 0.0 5.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EPE24148.1 - 0.0086 14.9 0.0 1.1 7.9 0.0 2.3 2 0 0 2 2 2 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 EPE24148.1 - 0.01 14.4 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain VID27 PF08553.10 EPE24148.1 - 0.055 12.5 0.0 0.58 9.2 0.0 2.4 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Nup160 PF11715.8 EPE24148.1 - 0.16 10.6 0.0 8.1 5.0 0.0 2.7 2 1 0 3 3 3 0 Nucleoporin Nup120/160 DUF4211 PF13926.6 EPE24149.1 - 1.1e-12 48.3 0.0 2.4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) GPI2 PF06432.11 EPE24152.1 - 5.2e-131 436.2 1.3 6.1e-131 436.0 1.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3136 PF11334.8 EPE24152.1 - 0.19 11.6 0.2 0.36 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) DUF1422 PF07226.11 EPE24152.1 - 0.32 11.0 1.8 0.68 10.0 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) DUF4211 PF13926.6 EPE24154.1 - 6.4e-19 68.4 0.0 1.1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) Raptor_N PF14538.6 EPE24157.1 - 0.056 13.4 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain adh_short PF00106.25 EPE24158.1 - 6.9e-24 84.4 0.0 5.1e-22 78.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE24158.1 - 1.1e-11 44.8 0.0 4.8e-09 36.1 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE24158.1 - 1.4e-06 28.3 0.1 2.3e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE24158.1 - 0.007 15.9 0.0 0.02 14.4 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE24158.1 - 0.054 12.9 0.0 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase p450 PF00067.22 EPE24159.1 - 7.1e-51 173.4 0.0 9.1e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CHAT PF12770.7 EPE24160.1 - 1.7e-33 116.3 0.2 3.6e-33 115.2 0.2 1.6 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.6 EPE24160.1 - 0.0043 17.3 2.5 11 6.4 0.0 6.3 6 1 0 6 6 6 1 Tetratricopeptide repeat DUF4404 PF14357.6 EPE24160.1 - 0.033 14.8 0.7 13 6.5 0.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) TPR_10 PF13374.6 EPE24160.1 - 0.039 13.8 14.6 0.62 10.0 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 EPE24160.1 - 1.3 9.0 4.8 58 3.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EPE24160.1 - 5.7 7.3 12.0 38 4.7 0.0 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat PAP_assoc PF03828.19 EPE24163.1 - 1.3e-16 60.5 0.1 2.7e-15 56.3 0.1 2.5 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EPE24163.1 - 2.6e-05 24.4 0.0 6.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EPE24163.1 - 0.015 15.3 0.0 0.043 13.9 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Macoilin PF09726.9 EPE24163.1 - 7.6 5.0 7.2 11 4.5 7.2 1.2 1 0 0 1 1 1 0 Macoilin family TFIIF_alpha PF05793.12 EPE24164.1 - 2.4e-07 29.7 64.7 4.8e-07 28.8 53.4 4.5 1 1 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Orthopox_B11R PF07033.11 EPE24164.1 - 1.7 8.4 5.7 11 5.8 0.2 2.9 3 0 0 3 3 3 0 Orthopoxvirus B11R protein Bud13 PF09736.9 EPE24165.1 - 2e-34 119.1 14.9 2e-34 119.1 14.9 2.3 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex HTH_Tnp_Mu_1 PF02316.16 EPE24165.1 - 0.24 11.6 3.9 0.64 10.2 3.9 1.7 1 0 0 1 1 1 0 Mu DNA-binding domain zf-met PF12874.7 EPE24166.1 - 0.079 13.4 0.3 0.3 11.5 0.3 2.1 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF2207 PF09972.9 EPE24167.1 - 1.1 7.9 2.7 1.6 7.4 2.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Aldo_ket_red PF00248.21 EPE24169.1 - 1.5e-65 221.3 0.0 1.8e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Gp-FAR-1 PF05823.12 EPE24170.1 - 0.054 13.9 0.0 0.17 12.2 0.0 1.7 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Zip PF02535.22 EPE24170.1 - 7.4 5.7 6.3 1.2 8.3 0.9 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter SPRY PF00622.28 EPE24172.1 - 1.2e-06 28.6 0.0 2.1e-05 24.6 0.0 2.5 3 0 0 3 3 3 1 SPRY domain CEND1 PF15677.5 EPE24172.1 - 0.52 10.9 8.3 1.1 9.7 8.3 1.5 1 0 0 1 1 1 0 Cell cycle exit and neuronal differentiation protein 1 LptF_LptG PF03739.14 EPE24173.1 - 0.0062 15.4 0.0 0.0074 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG Tweety PF04906.13 EPE24173.1 - 0.0084 14.8 1.4 0.011 14.4 1.4 1.2 1 0 0 1 1 1 1 Tweety DUF1700 PF08006.11 EPE24173.1 - 1.6 8.3 10.0 1 8.8 7.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) BDV_P40 PF06407.11 EPE24174.1 - 0.08 12.0 0.1 0.4 9.7 0.0 1.8 2 0 0 2 2 2 0 Borna disease virus P40 protein zf-RING_2 PF13639.6 EPE24175.1 - 2.2e-12 47.1 5.1 3.5e-12 46.5 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 EPE24175.1 - 3.7e-10 39.7 0.0 9.4e-10 38.4 0.0 1.8 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.7 EPE24175.1 - 5.3e-09 36.2 2.2 1e-08 35.3 2.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EPE24175.1 - 5.5e-09 35.7 4.0 8.7e-09 35.1 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE24175.1 - 1.3e-08 34.5 2.7 2.1e-08 33.9 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EPE24175.1 - 1.4e-08 34.3 2.2 1.4e-08 34.3 2.2 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 EPE24175.1 - 1.3e-06 28.2 2.0 2e-06 27.6 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EPE24175.1 - 2e-05 24.4 2.8 2.9e-05 23.8 2.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE24175.1 - 2.7e-05 24.1 1.8 6.1e-05 23.0 0.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EPE24175.1 - 0.0014 18.6 0.9 0.0027 17.7 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EPE24175.1 - 0.014 15.2 2.7 0.024 14.5 2.7 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EPE24175.1 - 0.037 14.2 2.8 0.09 13.0 2.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EPE24175.1 - 0.081 12.6 3.2 0.16 11.7 3.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EPE24175.1 - 0.13 12.5 1.7 0.31 11.2 1.7 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EPE24175.1 - 0.2 12.0 3.0 0.34 11.3 3.0 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 EPE24175.1 - 0.34 11.1 2.7 0.65 10.2 2.5 1.6 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 EPE24175.1 - 0.42 10.4 2.6 0.78 9.6 2.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 EPE24175.1 - 0.79 9.7 2.4 1.5 8.8 2.4 1.5 1 0 0 1 1 1 0 PHD-finger MIP PF00230.20 EPE24176.1 - 2.2e-49 168.2 16.3 2.9e-49 167.8 16.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein AXE1 PF05448.12 EPE24177.1 - 3.3e-05 22.7 0.0 0.0013 17.5 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EPE24177.1 - 0.0022 17.5 0.0 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 EPE24177.1 - 0.011 15.2 0.0 0.027 14.0 0.0 1.6 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 EPE24177.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EPE24177.1 - 0.18 11.6 0.0 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase VCBS PF13517.6 EPE24178.1 - 5.4e-29 100.6 26.3 3.1e-12 46.9 0.9 7.3 3 3 5 8 8 8 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 EPE24178.1 - 3.1e-15 57.0 0.0 2.7e-14 54.0 0.0 2.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE24178.1 - 8.1e-11 42.3 0.2 1.6e-10 41.3 0.2 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 EPE24178.1 - 6.8e-05 22.3 6.9 3.8 6.8 0.1 6.4 3 2 4 7 7 7 3 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 EPE24178.1 - 0.0019 18.3 25.3 0.84 9.8 0.1 6.0 5 0 0 5 5 5 4 FG-GAP repeat PliI PF16743.5 EPE24178.1 - 0.0028 17.4 0.3 8.3 6.2 0.0 4.2 3 1 1 4 4 4 1 Periplasmic lysozyme inhibitor of I-type lysozyme Lipase_GDSL_3 PF14606.6 EPE24178.1 - 0.0044 17.2 0.1 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SprT-like PF10263.9 EPE24179.1 - 0.0011 18.8 0.8 0.0021 17.9 0.8 1.6 1 1 0 1 1 1 1 SprT-like family Zn_clus PF00172.18 EPE24180.1 - 3.2e-07 30.4 14.0 5.2e-07 29.7 14.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Anoctamin PF04547.12 EPE24183.1 - 3.4e-114 382.1 3.0 4.2e-114 381.9 3.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Metallophos PF00149.28 EPE24184.1 - 3.8e-11 43.9 0.1 6.6e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPE24184.1 - 2.2e-05 24.7 0.2 0.0003 21.0 0.1 2.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Vps62 PF06101.11 EPE24185.1 - 9e-12 44.1 0.8 3.1e-10 39.0 0.5 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 Myb_DNA-binding PF00249.31 EPE24186.1 - 0.00055 20.1 0.0 0.0021 18.2 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain UPF0016 PF01169.19 EPE24187.1 - 6e-41 138.6 24.7 2.2e-21 75.9 9.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 EPE24187.1 - 0.0022 17.8 0.1 0.0022 17.8 0.1 1.9 2 0 0 2 2 2 1 Putative manganese efflux pump DUF1996 PF09362.10 EPE24188.1 - 3.7e-78 262.7 0.5 3.7e-78 262.7 0.5 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) RNA_pol_3_Rpc31 PF11705.8 EPE24190.1 - 2e-56 191.8 10.4 2.4e-56 191.5 10.4 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Bac_rhodopsin PF01036.18 EPE24192.1 - 2e-58 197.6 19.1 2.4e-58 197.3 19.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MARVEL PF01284.23 EPE24192.1 - 1.9 8.5 14.3 3.3 7.7 3.1 2.3 2 0 0 2 2 2 0 Membrane-associating domain TssN PF17555.2 EPE24192.1 - 2 7.7 8.3 0.54 9.6 1.4 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF3810 PF12725.7 EPE24192.1 - 4.6 6.5 9.5 3.2 7.0 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) RPE65 PF03055.15 EPE24193.1 - 1e-118 397.5 0.0 1.2e-118 397.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF825 PF05695.12 EPE24193.1 - 0.052 10.7 0.2 0.072 10.3 0.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) SQS_PSY PF00494.19 EPE24194.1 - 2.7e-65 220.5 0.1 3.5e-65 220.1 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase 4HB PF17947.1 EPE24194.1 - 0.14 12.2 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 Four helical bundle domain Peptidase_C48 PF02902.19 EPE24195.1 - 2.3e-09 37.4 0.1 2.7e-08 33.9 0.1 2.2 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Amino_oxidase PF01593.24 EPE24196.1 - 9.1e-25 87.8 0.0 5.6e-23 82.0 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPE24196.1 - 2.6e-15 56.4 0.1 6.8e-15 55.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE24196.1 - 6.2e-13 49.1 0.3 6.3e-12 45.7 0.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPE24196.1 - 1.3e-09 37.7 1.1 2.4e-06 26.9 1.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EPE24196.1 - 5.7e-09 35.6 0.2 1.6e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE24196.1 - 6.6e-08 31.7 1.1 0.0027 16.5 0.9 2.1 2 0 0 2 2 2 2 HI0933-like protein MCRA PF06100.11 EPE24196.1 - 7.7e-07 28.3 0.0 0.0038 16.1 0.0 2.1 2 0 0 2 2 2 2 MCRA family FAD_oxidored PF12831.7 EPE24196.1 - 0.00016 21.1 4.7 0.0038 16.6 2.9 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPE24196.1 - 0.00026 20.3 3.6 0.0024 17.2 1.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 EPE24196.1 - 0.00087 17.9 0.2 0.064 11.8 0.0 2.1 2 0 0 2 2 2 1 GDP dissociation inhibitor FAD_binding_3 PF01494.19 EPE24196.1 - 0.0069 15.7 1.0 0.0095 15.2 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EPE24196.1 - 0.0084 16.6 3.2 0.83 10.3 1.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE24196.1 - 0.011 15.0 2.9 0.023 13.9 0.5 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 EPE24196.1 - 0.014 15.4 2.7 0.32 11.0 0.2 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 EPE24196.1 - 0.02 14.0 6.0 0.029 13.4 2.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Spore_YabQ PF09578.10 EPE24196.1 - 0.04 14.1 0.9 0.13 12.5 0.4 2.1 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) GMC_oxred_N PF00732.19 EPE24196.1 - 0.041 13.2 0.7 1.6 8.0 0.1 2.3 2 0 0 2 2 2 0 GMC oxidoreductase adh_short PF00106.25 EPE24196.1 - 0.081 12.4 2.0 0.66 9.4 1.3 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Trp_halogenase PF04820.14 EPE24196.1 - 0.13 11.1 4.3 2.2 7.0 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DUF5644 PF18712.1 EPE24196.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5644) 3HCDH_N PF02737.18 EPE24196.1 - 0.21 11.4 0.7 0.4 10.6 0.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EPE24196.1 - 0.35 10.1 3.9 0.43 9.8 0.6 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EPE24196.1 - 1.5 7.8 4.8 0.4 9.7 0.6 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein DEAD PF00270.29 EPE24197.1 - 6.1e-44 149.9 0.0 1.8e-43 148.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE24197.1 - 2.3e-28 98.8 0.0 5.9e-27 94.2 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EPE24197.1 - 1.6e-05 23.8 0.0 3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EPE24197.1 - 0.0079 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Septin PF00735.18 EPE24199.1 - 1.8e-30 106.2 0.0 4.7e-10 39.2 0.0 3.2 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.18 EPE24199.1 - 0.00069 19.0 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.20 EPE24199.1 - 0.018 14.3 0.0 0.046 12.9 0.0 1.6 1 0 0 1 1 1 0 G-protein alpha subunit Dynamin_N PF00350.23 EPE24199.1 - 0.039 14.0 0.7 0.1 12.6 0.1 1.9 2 0 0 2 2 2 0 Dynamin family AAA_28 PF13521.6 EPE24199.1 - 0.051 13.8 0.4 0.24 11.6 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EPE24199.1 - 0.15 12.5 0.1 0.59 10.5 0.0 2.0 3 0 0 3 3 3 0 AAA ATPase domain HET PF06985.11 EPE24200.1 - 1.7e-11 44.6 7.0 4.1e-10 40.2 1.1 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.11 EPE24201.1 - 8.4e-35 120.3 1.2 2.1e-34 119.0 1.2 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABC1 PF03109.16 EPE24202.1 - 3e-23 82.2 0.0 6.5e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EPE24202.1 - 0.15 12.0 0.1 0.31 10.9 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family SUR7 PF06687.12 EPE24203.1 - 3.1e-24 85.8 12.7 4.3e-24 85.3 12.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF1768 PF08719.11 EPE24205.1 - 1.1e-54 185.0 0.0 1.3e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) BCAS2 PF05700.11 EPE24206.1 - 0.057 13.1 0.1 0.066 12.9 0.1 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Acyl_transf_3 PF01757.22 EPE24207.1 - 1.4e-24 86.8 32.8 6.9e-24 84.5 32.8 1.8 1 1 0 1 1 1 1 Acyltransferase family Isochorismatase PF00857.20 EPE24208.1 - 5.2e-32 111.4 0.0 6.1e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Fungal_trans_2 PF11951.8 EPE24209.1 - 5.5e-11 41.9 0.0 7e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RCR PF12273.8 EPE24210.1 - 1.7e-14 54.5 18.2 3.5e-14 53.5 18.2 1.5 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red tRNA-synt_2c PF01411.19 EPE24212.1 - 1.2e-215 717.2 0.2 1.2e-215 717.2 0.2 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EPE24212.1 - 3.6e-17 62.2 0.5 8.4e-17 61.0 0.5 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EPE24212.1 - 3.6e-11 43.6 0.4 9.5e-11 42.3 0.4 1.8 1 0 0 1 1 1 1 DHHA1 domain DUF4559 PF15112.6 EPE24212.1 - 1.7 8.3 6.7 2.3 7.8 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) PdaC PF13739.6 EPE24212.1 - 3.2 8.8 5.1 18 6.4 0.0 3.2 3 0 0 3 3 3 0 Deacetylase PdaC AATase PF07247.12 EPE24213.1 - 2.7e-25 88.9 0.0 5.5e-25 87.9 0.0 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 EPE24213.1 - 0.00097 17.9 0.0 0.053 12.2 0.0 2.1 2 0 0 2 2 2 2 Condensation domain Bul1_N PF04425.12 EPE24215.1 - 2e-07 30.1 0.7 0.0061 15.4 0.1 3.1 2 1 1 3 3 3 2 Bul1 N terminus Arrestin_N PF00339.29 EPE24215.1 - 6.8e-07 29.4 0.0 1.4e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 EPE24215.1 - 0.057 12.8 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Bul1 C terminus MBOAT PF03062.19 EPE24217.1 - 8.5e-46 156.9 15.0 8.5e-46 156.9 15.0 1.9 3 0 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family adh_short PF00106.25 EPE24219.1 - 6.2e-24 84.5 0.0 1.1e-20 73.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE24219.1 - 9.4e-15 54.8 0.0 5.4e-13 49.0 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE24219.1 - 9.6e-05 22.4 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EPE24219.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TIR-like PF10137.9 EPE24219.1 - 0.18 11.7 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain THF_DHG_CYH_C PF02882.19 EPE24219.1 - 0.2 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Peptidase_S41 PF03572.18 EPE24220.1 - 6.2e-07 29.1 0.0 2.1e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase family S41 Ank_2 PF12796.7 EPE24221.1 - 6.3e-51 170.9 2.0 1.2e-10 41.9 0.2 7.8 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE24221.1 - 1.3e-44 150.0 7.2 8.1e-06 26.3 0.0 10.1 7 3 2 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE24221.1 - 1.6e-43 146.2 6.8 2.6e-06 27.6 0.0 9.6 6 2 5 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE24221.1 - 2.8e-31 104.0 12.9 0.00079 19.7 0.0 10.7 11 0 0 11 11 10 7 Ankyrin repeat Ank PF00023.30 EPE24221.1 - 8.9e-30 101.8 18.4 0.0019 18.5 0.3 11.0 11 0 0 11 11 11 8 Ankyrin repeat AAA_16 PF13191.6 EPE24221.1 - 0.0028 18.1 0.0 0.017 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Clathrin PF00637.20 EPE24221.1 - 0.008 16.1 2.9 0.034 14.0 2.0 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS SesA PF17107.5 EPE24221.1 - 0.058 13.6 0.1 0.058 13.6 0.1 3.9 2 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4449 PF14613.6 EPE24221.1 - 0.12 12.5 8.9 1.7 8.7 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Lipoprotein_2 PF00921.17 EPE24221.1 - 0.51 9.8 6.8 1.2 8.6 6.8 1.6 1 0 0 1 1 1 0 Borrelia lipoprotein Exonuc_VII_L PF02601.15 EPE24221.1 - 2.1 7.9 13.5 0.11 12.0 5.9 2.6 3 0 0 3 3 3 0 Exonuclease VII, large subunit SLX9 PF15341.6 EPE24221.1 - 8.5 6.8 12.4 39 4.6 12.4 2.1 1 1 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF2306 PF10067.9 EPE24223.1 - 5.3e-15 55.9 7.6 5.3e-15 55.9 7.6 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF5127 PF17168.4 EPE24224.1 - 1.4e-81 273.6 6.6 2.2e-81 273.0 6.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EPE24224.1 - 5.6e-74 247.5 0.7 8.9e-74 246.9 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EPE24224.1 - 3.2e-61 206.6 2.3 3.4e-61 206.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EPE24224.1 - 1.8e-08 33.8 0.0 5.5e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) DUF4518 PF15008.6 EPE24224.1 - 0.13 11.5 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Bap31 PF05529.12 EPE24225.1 - 1.2e-50 170.9 9.3 1.5e-50 170.6 9.3 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EPE24225.1 - 8.1e-14 51.4 0.9 1.7e-13 50.4 0.9 1.6 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 EPE24225.1 - 0.00014 21.5 1.0 0.01 15.6 0.2 2.7 2 0 0 2 2 2 1 Septum formation initiator HALZ PF02183.18 EPE24225.1 - 0.06 13.6 0.8 0.15 12.3 0.8 1.7 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF4472 PF14739.6 EPE24225.1 - 0.12 13.1 0.4 0.23 12.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Dus PF01207.17 EPE24226.1 - 1.5e-40 139.2 0.0 1.5e-29 103.1 0.0 2.7 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 EPE24226.1 - 0.0028 17.7 6.2 0.71 10.0 0.7 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EPE24226.1 - 0.043 13.6 6.5 0.29 11.0 0.1 3.0 3 0 0 3 3 3 0 CCCH-type zinc finger zf-CCCH PF00642.24 EPE24226.1 - 0.088 12.8 2.4 3.4 7.7 0.2 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_1 PF01344.25 EPE24227.1 - 1.2e-37 127.3 16.8 4.7e-07 29.3 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EPE24227.1 - 1.6e-37 126.9 11.3 1.2e-05 25.2 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EPE24227.1 - 1.3e-36 124.2 6.1 1.4e-06 28.5 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EPE24227.1 - 7.4e-34 114.9 9.4 2.7e-06 27.4 0.0 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EPE24227.1 - 4.2e-33 113.1 12.9 6.6e-06 26.0 0.1 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 EPE24227.1 - 5.1e-29 99.1 15.2 2.1e-05 24.3 0.0 6.5 6 1 0 6 6 6 6 Kelch motif HIG_1_N PF04588.13 EPE24228.1 - 6.9e-06 26.2 1.9 1.5e-05 25.1 1.9 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Hyphal_reg_CWP PF11765.8 EPE24228.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Hyphally regulated cell wall protein N-terminal Macoilin PF09726.9 EPE24228.1 - 0.29 9.6 18.6 0.4 9.2 18.6 1.3 1 0 0 1 1 1 0 Macoilin family SURF2 PF05477.11 EPE24228.1 - 7.3 6.2 21.7 12 5.5 21.7 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 EPE24228.1 - 8.6 4.5 20.5 13 3.9 20.5 1.3 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.13 EPE24228.1 - 9.7 6.0 29.5 17 5.2 29.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal zf-C2H2_aberr PF17017.5 EPE24229.1 - 6.3e-05 23.2 2.3 0.022 14.9 0.1 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 EPE24229.1 - 0.00012 22.4 11.1 0.065 13.7 1.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE24229.1 - 0.00024 21.6 11.4 0.021 15.7 1.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPE24229.1 - 0.0018 18.6 10.7 0.012 16.0 1.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EPE24229.1 - 0.17 12.2 5.1 1.5 9.2 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HET PF06985.11 EPE24230.1 - 4.2e-34 118.0 0.6 7.4e-34 117.2 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3425 PF11905.8 EPE24231.1 - 3.6e-12 46.3 2.9 2.5e-11 43.6 2.9 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EPE24231.1 - 0.00079 19.5 3.0 0.0016 18.5 3.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPE24231.1 - 0.064 13.4 4.3 0.12 12.5 4.3 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DUF4345 PF14248.6 EPE24232.1 - 0.094 12.6 8.0 2.6 8.0 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) Scm3 PF10384.9 EPE24233.1 - 8.6e-21 73.4 0.1 8.6e-21 73.4 0.1 2.1 2 0 0 2 2 2 1 Centromere protein Scm3 Myb_DNA-bind_2 PF08914.11 EPE24233.1 - 0.026 14.7 0.0 0.093 12.9 0.0 2.0 2 0 0 2 2 2 0 Rap1 Myb domain Rhabdo_ncap PF00945.18 EPE24233.1 - 5.5 5.8 6.1 9.3 5.0 6.1 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein APG6 PF04111.12 EPE24234.1 - 6e-74 247.9 0.0 8.9e-74 247.3 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EPE24234.1 - 3.8e-37 127.8 12.8 6.2e-37 127.1 12.8 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region UPF0242 PF06785.11 EPE24234.1 - 2.4 8.2 11.3 3.9 7.5 11.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Pkinase PF00069.25 EPE24235.1 - 4.6e-40 137.7 0.5 1.1e-37 129.9 0.5 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE24235.1 - 2.3e-06 27.1 0.4 0.00022 20.6 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase CPSase_sm_chain PF00988.22 EPE24237.1 - 6.6e-48 161.8 0.0 1.3e-47 160.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EPE24237.1 - 6e-45 153.4 0.1 8.2e-45 152.9 0.1 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EPE24237.1 - 3.4e-05 23.7 0.1 0.0062 16.3 0.2 2.9 2 1 1 3 3 3 2 Peptidase C26 DJ-1_PfpI PF01965.24 EPE24237.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family ETF PF01012.21 EPE24238.1 - 2.1e-42 145.1 0.1 2.5e-42 144.8 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PRK PF00485.18 EPE24239.1 - 0.024 14.4 0.0 0.42 10.3 0.0 2.6 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Bac_luciferase PF00296.20 EPE24240.1 - 3e-65 220.7 0.0 4.3e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_zinc_N PF00107.26 EPE24241.1 - 6.5e-07 29.4 0.2 1.2e-06 28.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE24241.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Gpr1_Fun34_YaaH PF01184.19 EPE24242.1 - 3.4e-41 141.1 24.4 4.6e-41 140.7 24.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Herpes_UL73 PF03554.13 EPE24242.1 - 0.22 11.6 2.9 0.56 10.2 2.9 1.7 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein Acyl-CoA_dh_2 PF08028.11 EPE24243.1 - 2e-13 50.8 0.5 3.5e-13 50.0 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EPE24243.1 - 3e-07 31.1 0.1 6.9e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EPE24243.1 - 0.00029 21.0 0.1 0.00051 20.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EPE24243.1 - 0.0032 17.6 0.1 0.031 14.5 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain SlyX PF04102.12 EPE24245.1 - 0.049 14.3 5.6 3.2 8.4 0.1 3.4 3 0 0 3 3 3 0 SlyX bZIP_1 PF00170.21 EPE24245.1 - 0.082 13.0 10.6 0.15 12.2 0.4 3.0 3 0 0 3 3 3 0 bZIP transcription factor SOGA PF11365.8 EPE24245.1 - 0.09 13.9 8.6 1.6 9.9 0.7 3.5 3 0 0 3 3 3 0 Protein SOGA NRBF2_MIT PF17169.4 EPE24245.1 - 0.12 12.7 2.3 0.28 11.4 2.3 1.7 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 GAS PF13851.6 EPE24245.1 - 0.19 11.0 4.9 0.83 9.0 0.7 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DASH_Spc19 PF08287.11 EPE24245.1 - 0.2 11.6 12.2 1.2 9.0 0.9 3.5 2 1 1 3 3 3 0 Spc19 CENP-F_leu_zip PF10473.9 EPE24245.1 - 0.2 11.7 4.5 0.48 10.4 0.6 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnn_1N PF07989.11 EPE24245.1 - 0.26 11.5 3.2 1.6 8.9 0.5 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 EPE24245.1 - 0.38 10.6 7.9 6.6 6.6 3.1 2.6 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 EPE24245.1 - 0.51 10.8 13.8 2 8.9 0.7 3.1 3 0 0 3 3 3 0 Cell division protein ZapB Ax_dynein_light PF10211.9 EPE24245.1 - 0.59 10.1 6.1 6.8 6.6 1.5 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain FlaC_arch PF05377.11 EPE24245.1 - 1.4 9.4 3.3 14 6.1 0.3 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 EPE24245.1 - 1.8 8.9 4.1 5.3 7.3 0.3 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.20 EPE24245.1 - 2 8.4 5.0 25 4.9 0.3 2.5 2 0 0 2 2 2 0 Prefoldin subunit KASH_CCD PF14662.6 EPE24245.1 - 2.2 8.1 6.2 14 5.5 6.2 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Tropomyosin_1 PF12718.7 EPE24245.1 - 4.3 7.5 11.5 4.4 7.4 6.4 2.5 2 1 1 3 3 2 0 Tropomyosin like ABC_tran_CTD PF16326.5 EPE24245.1 - 8.2 6.8 9.3 18 5.7 2.0 3.4 3 1 0 3 3 3 0 ABC transporter C-terminal domain TRI12 PF06609.13 EPE24246.1 - 4.4e-75 253.3 21.8 5.8e-75 252.9 21.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EPE24246.1 - 1.4e-25 90.0 43.7 1.4e-25 90.0 43.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE24246.1 - 2.2e-08 33.4 8.0 2.2e-08 33.4 8.0 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Transp_inhibit PF18791.1 EPE24246.1 - 0.031 13.8 0.1 0.064 12.8 0.1 1.4 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain TMEM100 PF16311.5 EPE24246.1 - 0.43 10.2 3.1 0.66 9.6 0.1 2.6 3 0 0 3 3 3 0 Transmembrane protein 100 adh_short_C2 PF13561.6 EPE24247.1 - 9.6e-58 195.5 2.5 1.1e-57 195.3 2.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE24247.1 - 2.8e-47 160.7 2.7 3.3e-47 160.5 2.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE24247.1 - 1.8e-11 44.3 0.4 3.5e-11 43.3 0.4 1.5 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.18 EPE24248.1 - 6.9e-09 35.7 7.8 6.9e-09 35.7 7.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 EPE24249.1 - 1.2e-79 268.6 0.9 6.1e-79 266.2 0.9 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE24249.1 - 6.6e-10 39.2 0.4 3.8e-09 36.7 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPE24249.1 - 0.009 15.5 0.7 0.02 14.4 0.7 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family MFS_1 PF07690.16 EPE24250.1 - 1.1e-37 129.8 53.2 1.3e-36 126.3 50.8 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE24250.1 - 1.1e-22 80.3 24.5 1.4e-22 79.9 24.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPE24250.1 - 4.6e-12 45.5 6.6 4.6e-12 45.5 6.6 2.8 2 1 0 3 3 3 1 Sugar (and other) transporter DUF3522 PF12036.8 EPE24250.1 - 0.021 15.1 0.3 0.021 15.1 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3522) ABC_tran PF00005.27 EPE24251.1 - 3.6e-45 153.9 5.2 2.1e-23 83.4 0.1 3.6 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EPE24251.1 - 2.1e-17 63.9 7.6 2.4e-05 24.3 0.1 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPE24251.1 - 6.1e-11 42.2 0.3 0.0053 16.2 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EPE24251.1 - 5.3e-08 32.5 2.7 0.00082 19.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EPE24251.1 - 1.3e-06 28.7 6.1 0.014 15.6 0.2 4.0 3 2 1 4 4 3 2 AAA domain AAA_30 PF13604.6 EPE24251.1 - 4.8e-06 26.4 3.4 0.043 13.5 0.0 3.7 2 2 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EPE24251.1 - 7.5e-06 26.0 0.1 0.034 14.2 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 EPE24251.1 - 1.2e-05 25.8 0.1 0.02 15.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPE24251.1 - 1.6e-05 25.4 6.6 0.044 14.2 2.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain ABC_tran_Xtn PF12848.7 EPE24251.1 - 3.6e-05 23.7 6.7 3.6e-05 23.7 6.7 1.9 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 EPE24251.1 - 0.00016 22.1 0.3 0.028 14.8 0.0 3.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EPE24251.1 - 0.0002 20.9 0.2 0.04 13.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EPE24251.1 - 0.00047 20.4 3.4 0.87 9.8 1.1 3.6 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EPE24251.1 - 0.00051 20.2 5.6 0.46 10.6 0.0 3.7 4 1 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 EPE24251.1 - 0.00054 19.9 0.2 1.3 8.9 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase DUF815 PF05673.13 EPE24251.1 - 0.00095 18.4 0.2 0.4 9.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) MeaB PF03308.16 EPE24251.1 - 0.0018 17.4 1.0 0.089 11.8 0.1 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 EPE24251.1 - 0.0021 17.8 10.2 1.4 8.5 0.0 3.5 2 1 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 EPE24251.1 - 0.004 17.1 0.2 3.1 7.7 0.1 3.5 4 0 0 4 4 4 1 NTPase AAA_5 PF07728.14 EPE24251.1 - 0.0062 16.5 0.3 3.8 7.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EPE24251.1 - 0.0091 16.4 0.1 2.5 8.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 EPE24251.1 - 0.018 14.7 0.8 4.7 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EPE24251.1 - 0.023 14.6 1.8 3 7.7 0.0 2.8 3 0 0 3 3 2 0 NACHT domain AAA_14 PF13173.6 EPE24251.1 - 0.025 14.6 0.2 11 6.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 EPE24251.1 - 0.031 14.3 4.1 2.5 8.1 0.6 3.3 3 1 0 3 3 3 0 Dynamin family Roc PF08477.13 EPE24251.1 - 0.064 13.5 0.1 13 6.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EPE24251.1 - 0.066 13.7 22.5 0.92 10.0 0.1 3.8 3 1 0 3 3 3 0 AAA domain G-alpha PF00503.20 EPE24251.1 - 0.08 12.1 1.3 6.5 5.8 0.3 2.6 2 1 0 2 2 2 0 G-protein alpha subunit TsaE PF02367.17 EPE24251.1 - 0.13 12.2 0.9 8.8 6.4 0.0 2.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EPE24251.1 - 1.9 8.0 4.8 9.3 5.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EPE24251.1 - 2.7 7.1 7.7 3.8 6.6 0.0 3.1 4 0 0 4 4 4 0 NB-ARC domain MukB PF04310.12 EPE24251.1 - 3 7.6 5.6 0.76 9.5 0.1 2.7 4 0 0 4 4 3 0 MukB N-terminal DUF2813 PF11398.8 EPE24251.1 - 3.3 6.9 7.2 8.2 5.6 0.3 3.4 4 0 0 4 4 3 0 Protein of unknown function (DUF2813) Arf PF00025.21 EPE24251.1 - 4.1 6.8 7.0 4.2 6.8 0.5 2.9 3 0 0 3 3 3 0 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 EPE24251.1 - 5.1 6.4 6.4 4 6.7 0.1 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family Thymidylate_kin PF02223.17 EPE24251.1 - 6.7 6.3 9.8 3.9 7.1 0.0 3.5 4 0 0 4 4 4 0 Thymidylate kinase FMO-like PF00743.19 EPE24253.1 - 1e-12 47.3 0.0 5.6e-10 38.2 0.1 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EPE24253.1 - 7.5e-12 45.3 0.0 1.8e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EPE24253.1 - 5.5e-06 25.8 0.0 4.9e-05 22.7 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPE24253.1 - 1.9e-05 24.0 0.0 0.01 15.1 0.0 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPE24253.1 - 2.9e-05 23.4 0.1 0.9 8.6 0.0 3.4 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EPE24253.1 - 0.00027 20.9 0.0 0.0013 18.7 0.0 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 EPE24253.1 - 0.00088 18.9 0.0 0.71 9.4 0.0 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 EPE24253.1 - 0.024 13.9 0.0 0.072 12.3 0.0 1.7 2 0 0 2 2 2 0 Thi4 family adh_short_C2 PF13561.6 EPE24254.1 - 1.6e-55 188.2 0.0 1.8e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE24254.1 - 4.3e-43 147.1 0.0 5.7e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE24254.1 - 9.1e-10 38.7 0.1 1.3e-09 38.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 EPE24254.1 - 0.0015 18.7 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.21 EPE24254.1 - 0.0094 15.4 0.1 0.015 14.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EPE24254.1 - 0.017 14.3 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HHH_5 PF14520.6 EPE24254.1 - 0.18 12.4 0.9 0.4 11.3 0.1 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix domain C5-epim_C PF06662.13 EPE24255.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Fungal_trans PF04082.18 EPE24256.1 - 4e-14 52.3 0.0 1.5e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE24256.1 - 1.2e-07 31.7 9.2 3.2e-07 30.3 9.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AtuA PF07287.11 EPE24257.1 - 6.3e-130 433.0 0.1 7.6e-130 432.7 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Abhydrolase_3 PF07859.13 EPE24258.1 - 6.5e-57 192.8 0.0 8.5e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EPE24258.1 - 8.3e-07 28.2 0.0 2.2e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 EPE24258.1 - 7.1e-06 25.1 0.0 9.6e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 EPE24258.1 - 0.0032 18.1 0.0 0.0074 16.9 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Acyl-CoA_dh_1 PF00441.24 EPE24259.1 - 5.5e-26 91.6 0.1 8.3e-26 91.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EPE24259.1 - 7.2e-13 49.2 0.1 3.3e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EPE24259.1 - 4.1e-10 39.7 0.0 1e-09 38.5 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EPE24259.1 - 1.2e-09 38.6 0.0 2.3e-09 37.6 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Glyco_hydro_114 PF03537.13 EPE24260.1 - 1e-61 208.2 0.0 1.3e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 DUF4286 PF14114.6 EPE24262.1 - 0.0011 19.4 0.1 0.1 13.1 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4286) EthD PF07110.11 EPE24262.1 - 0.09 13.9 1.9 0.15 13.2 0.1 2.2 3 0 0 3 3 3 0 EthD domain Aldedh PF00171.22 EPE24263.1 - 1.3e-153 511.9 0.0 1.5e-153 511.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Rick_17kDa_Anti PF05433.15 EPE24264.1 - 0.031 14.2 6.7 1.6 8.7 1.6 2.2 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.6 EPE24264.1 - 1.1 9.0 5.8 2 8.2 5.8 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper TSSC4 PF15264.6 EPE24265.1 - 0.072 13.4 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 Fungal_trans PF04082.18 EPE24266.1 - 1.4e-23 83.3 0.0 3.7e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE24266.1 - 0.00029 20.9 11.4 0.0006 19.9 11.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clp1 PF06807.14 EPE24266.1 - 0.15 12.5 0.4 2.6 8.5 0.0 3.0 4 0 0 4 4 4 0 Pre-mRNA cleavage complex II protein Clp1 FMO-like PF00743.19 EPE24267.1 - 9.6e-14 50.7 0.1 2.9e-12 45.8 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EPE24267.1 - 1.9e-12 47.2 0.0 5.4e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EPE24267.1 - 3.5e-06 26.4 0.0 0.02 14.1 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EPE24267.1 - 0.0001 22.4 0.0 0.00036 20.6 0.0 2.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 EPE24267.1 - 0.016 14.8 0.0 0.064 12.8 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF4047 PF13256.6 EPE24267.1 - 0.037 14.2 0.5 1 9.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Pyr_redox_3 PF13738.6 EPE24267.1 - 0.15 11.3 0.0 5.2 6.2 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.28 EPE24268.1 - 4.9e-88 295.6 0.0 8e-88 294.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE24268.1 - 6.3e-11 43.1 0.8 6.3e-11 43.1 0.8 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.6 EPE24269.1 - 1.1e-48 165.9 0.2 1.5e-48 165.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE24269.1 - 2.6e-41 141.2 0.3 3.5e-41 140.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE24269.1 - 8.8e-12 45.3 0.4 1.5e-11 44.6 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE24269.1 - 0.05 13.1 0.2 0.35 10.3 0.2 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH PF00763.23 EPE24269.1 - 0.17 12.2 0.0 0.74 10.1 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain p450 PF00067.22 EPE24270.1 - 8.8e-78 262.1 0.0 1.2e-77 261.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sigma70_r2 PF04542.14 EPE24270.1 - 0.0076 16.0 0.4 0.044 13.5 0.1 2.3 2 0 0 2 2 2 1 Sigma-70 region 2 DUF1924 PF09086.11 EPE24270.1 - 0.18 12.2 0.1 7.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) CorA PF01544.18 EPE24271.1 - 0.00017 21.0 1.1 0.00037 19.9 1.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sec6 PF06046.13 EPE24271.1 - 0.00023 19.7 0.3 0.00044 18.8 0.0 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec6 CSG2 PF16965.5 EPE24271.1 - 0.059 12.3 1.7 0.087 11.8 1.7 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator RdRP PF05183.12 EPE24272.1 - 1.5e-185 618.2 0.0 3e-185 617.3 0.0 1.5 2 0 0 2 2 2 1 RNA dependent RNA polymerase AAA_assoc_2 PF16193.5 EPE24272.1 - 0.036 14.4 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA C-terminal domain MORN PF02493.20 EPE24272.1 - 0.21 11.6 0.4 17 5.5 0.0 2.7 2 0 0 2 2 2 0 MORN repeat Fumble PF03630.14 EPE24274.1 - 8.6e-146 485.3 0.0 1.1e-145 485.0 0.0 1.1 1 0 0 1 1 1 1 Fumble 2OG-FeII_Oxy_3 PF13640.6 EPE24279.1 - 2.4e-10 41.1 0.0 4.7e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short_C2 PF13561.6 EPE24280.1 - 9.1e-42 143.2 0.0 1.7e-39 135.8 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE24280.1 - 1e-30 106.7 0.1 1.4e-28 99.7 0.1 2.6 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EPE24280.1 - 8.1e-10 38.9 0.0 1.2e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 KR domain MoaE PF02391.17 EPE24281.1 - 3.6e-39 133.5 0.1 4.7e-39 133.2 0.1 1.2 1 0 0 1 1 1 1 MoaE protein RRM_1 PF00076.22 EPE24283.1 - 3.5e-12 46.0 0.5 0.00023 20.9 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 EPE24283.1 - 2.1e-09 37.1 4.7 3.5e-09 36.4 2.2 2.3 2 0 0 2 2 2 1 G-patch domain zf-RanBP PF00641.18 EPE24283.1 - 8.8e-08 31.3 1.8 1.8e-07 30.4 1.8 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 EPE24283.1 - 9.4e-07 28.8 0.3 3.4e-06 27.1 0.3 2.0 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 EPE24283.1 - 0.00053 20.2 3.8 0.0013 19.0 3.8 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding RED_N PF07808.13 EPE24283.1 - 0.0042 16.7 0.6 0.0042 16.7 0.6 2.7 4 0 0 4 4 4 1 RED-like protein N-terminal region zf-C2H2_2 PF12756.7 EPE24283.1 - 0.043 14.2 0.3 0.11 12.9 0.3 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Glyco_hydro_53 PF07745.13 EPE24284.1 - 9e-102 340.5 0.1 1e-101 340.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Sec63 PF02889.16 EPE24285.1 - 1.3e-135 450.6 0.6 2.5e-81 272.6 0.5 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EPE24285.1 - 1.4e-50 171.5 0.0 1.6e-25 89.9 0.4 2.9 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 EPE24285.1 - 3.2e-20 72.8 0.0 3.5e-10 40.1 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EPE24285.1 - 2e-16 60.3 0.1 1.1e-06 28.9 0.0 4.7 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EPE24285.1 - 4.3e-08 33.5 0.4 0.0057 16.9 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 EPE24285.1 - 1.9e-07 31.0 0.1 0.0062 16.3 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EPE24285.1 - 0.00013 22.3 0.1 0.0077 16.6 0.3 2.6 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 EPE24285.1 - 0.00046 20.3 0.0 0.0014 18.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal helicase PWI domain IstB_IS21 PF01695.17 EPE24285.1 - 0.11 12.2 0.1 9.7 5.9 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein bZIP_1 PF00170.21 EPE24286.1 - 1e-08 35.2 7.5 4.4e-08 33.1 7.5 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPE24286.1 - 3.5 7.8 8.1 30 4.8 8.1 2.2 1 1 0 1 1 1 0 Basic region leucine zipper Actin PF00022.19 EPE24287.1 - 2.2e-51 174.8 0.0 1.4e-48 165.6 0.0 2.3 1 1 0 1 1 1 1 Actin DASH_Dad4 PF08650.10 EPE24288.1 - 2.8e-31 107.3 6.8 3.2e-31 107.1 6.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 EPE24288.1 - 0.01 16.0 0.4 0.013 15.7 0.4 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor CpXC PF14353.6 EPE24288.1 - 0.093 12.8 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 CpXC protein YL1_C PF08265.11 EPE24289.1 - 4.9e-17 61.4 0.3 7.9e-17 60.7 0.3 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain KdpC PF02669.15 EPE24289.1 - 0.044 13.6 0.3 0.07 13.0 0.3 1.3 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Profilin PF00235.19 EPE24290.1 - 1.5e-50 170.7 0.4 1.7e-50 170.6 0.4 1.0 1 0 0 1 1 1 1 Profilin Ank_3 PF13606.6 EPE24291.1 - 0.05 14.2 0.0 5.2 8.0 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 EPE24291.1 - 0.12 13.0 0.0 3.2 8.4 0.0 2.6 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Chorion_2 PF03964.15 EPE24292.1 - 9.5 7.1 8.1 1.8 9.5 2.2 2.7 2 0 0 2 2 2 0 Chorion family 2 FAD-oxidase_C PF02913.19 EPE24293.1 - 2.6e-65 220.5 0.1 3.6e-65 220.1 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EPE24293.1 - 1e-33 116.0 0.0 1.9e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 EPE24293.1 - 0.0072 15.1 0.1 0.023 13.4 0.0 1.7 2 0 0 2 2 2 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Ribosomal_S4e PF00900.20 EPE24294.1 - 3.2e-37 126.3 0.3 7.9e-37 125.0 0.3 1.7 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EPE24294.1 - 3.6e-24 84.1 0.1 6.2e-24 83.4 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EPE24294.1 - 4.1e-18 65.2 5.9 7.4e-18 64.4 5.9 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EPE24294.1 - 1.9e-07 30.7 0.0 3.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EPE24294.1 - 0.0032 17.4 3.5 0.0032 17.4 3.5 2.9 3 0 0 3 3 3 1 KOW motif Semialdhyde_dhC PF02774.18 EPE24295.1 - 4.5e-39 134.4 0.0 6.1e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EPE24295.1 - 6.3e-31 107.3 0.0 3.5e-30 104.9 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EPE24295.1 - 0.0011 19.1 0.1 0.0047 17.0 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 EPE24295.1 - 0.027 14.7 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 EPE24295.1 - 0.046 14.4 0.0 0.13 13.0 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase ApbA_C PF08546.11 EPE24296.1 - 1.7e-23 83.2 0.1 3e-23 82.4 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EPE24296.1 - 1.3e-09 37.9 0.0 3.1e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sas10_Utp3 PF04000.15 EPE24297.1 - 5.6e-17 62.1 0.3 5.6e-17 62.1 0.3 2.1 2 1 0 2 2 2 1 Sas10/Utp3/C1D family SR-25 PF10500.9 EPE24297.1 - 0.17 11.4 27.3 0.27 10.8 27.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SRP-alpha_N PF04086.13 EPE24297.1 - 4.9 7.0 23.8 5.9 6.7 23.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal XRN_M PF17846.1 EPE24297.1 - 6.9 5.5 11.3 0.13 11.2 1.8 2.0 1 1 1 2 2 2 0 Xrn1 helical domain DUF2076 PF09849.9 EPE24298.1 - 9.6e-07 29.1 14.1 1.2e-06 28.8 14.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EPE24298.1 - 1.7e-06 28.0 4.1 2.4e-06 27.5 4.1 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EPE24298.1 - 0.012 15.6 1.4 0.021 14.9 1.4 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Trypan_glycop_C PF10659.9 EPE24298.1 - 0.021 15.2 2.1 0.04 14.3 2.1 1.4 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain MTCP1 PF08991.10 EPE24298.1 - 0.17 12.2 2.2 0.26 11.5 2.2 1.2 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type WD40 PF00400.32 EPE24299.1 - 4.3e-16 59.0 17.6 0.00084 20.1 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE24299.1 - 0.00064 20.0 0.0 0.026 14.8 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EPE24299.1 - 0.02 13.4 0.2 1.8 7.0 0.0 3.3 4 0 0 4 4 4 0 Cytochrome D1 heme domain CDC27 PF09507.10 EPE24299.1 - 0.12 11.8 4.9 0.22 10.9 4.9 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SDA1 PF05285.12 EPE24299.1 - 0.78 9.1 10.9 1.2 8.5 10.9 1.3 1 0 0 1 1 1 0 SDA1 PD40 PF07676.12 EPE24299.1 - 0.83 9.7 0.0 0.83 9.7 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat CDC45 PF02724.14 EPE24299.1 - 5.4 5.2 9.8 7.6 4.7 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_25 PF13649.6 EPE24300.1 - 2e-18 66.9 0.0 3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE24300.1 - 3e-17 63.0 0.0 4.3e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE24300.1 - 9.6e-14 51.5 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE24300.1 - 1.9e-12 47.8 0.0 2.7e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE24300.1 - 2.7e-12 46.7 0.0 3.2e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EPE24300.1 - 7.7e-08 32.0 0.0 9.2e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EPE24300.1 - 2.1e-07 30.5 0.0 3.8e-07 29.7 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EPE24300.1 - 4e-07 29.7 0.0 6.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 EPE24300.1 - 0.0005 19.6 0.0 0.14 11.6 0.0 2.7 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.9 EPE24300.1 - 0.0026 17.5 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_PK PF05891.12 EPE24300.1 - 0.0032 17.0 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase TehB PF03848.14 EPE24300.1 - 0.008 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_33 PF10017.9 EPE24300.1 - 0.0091 15.2 0.1 0.023 13.8 0.1 1.6 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltr_RsmB-F PF01189.17 EPE24300.1 - 0.029 14.0 0.0 4.2 7.0 0.0 2.1 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F UPF0146 PF03686.13 EPE24300.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) RrnaAD PF00398.20 EPE24300.1 - 0.17 10.9 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ras PF00071.22 EPE24301.1 - 4.9e-46 156.3 0.0 6.1e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE24301.1 - 4.6e-14 52.7 0.0 7.2e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RRM_1 PF00076.22 EPE24302.1 - 6.1e-09 35.6 0.0 1.7e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hid1 PF12722.7 EPE24302.1 - 4.9 5.2 11.8 6.7 4.7 11.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CFEM PF05730.11 EPE24303.1 - 5.6e-10 39.2 7.8 7.8e-10 38.7 7.8 1.2 1 0 0 1 1 1 1 CFEM domain CMS1 PF14617.6 EPE24304.1 - 2.3e-84 282.7 3.1 2.8e-84 282.4 3.1 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EPE24304.1 - 2.4e-05 24.2 0.1 5.5e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase CENP-T_C PF15511.6 EPE24305.1 - 4.3e-46 155.5 0.0 7.4e-46 154.7 0.0 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EPE24305.1 - 3.1e-06 27.5 0.0 5.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 EPE24305.1 - 0.021 15.2 0.0 0.021 15.2 0.0 2.2 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 SURF1 PF02104.15 EPE24306.1 - 1.8e-47 161.9 0.0 2.3e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 SURF1 family UBX PF00789.20 EPE24307.1 - 1.7e-11 44.2 0.0 3.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 UBX domain Myb_DNA-binding PF00249.31 EPE24308.1 - 5.1e-17 61.8 0.1 5.7e-09 36.0 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPE24308.1 - 9.9e-15 54.5 0.0 7.7e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EPE24308.1 - 2.7e-06 27.4 0.6 0.099 12.7 0.0 2.6 3 0 0 3 3 3 2 SLIDE CHDCT2 PF08074.11 EPE24308.1 - 0.044 14.0 0.1 0.8 9.9 0.0 2.6 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain SET PF00856.28 EPE24310.1 - 9.1e-09 35.9 0.0 2.5e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 SET domain UbiA PF01040.18 EPE24311.1 - 1.9e-06 27.4 2.0 1.9e-06 27.4 2.0 1.6 1 1 1 2 2 2 1 UbiA prenyltransferase family FAM222A PF15258.6 EPE24311.1 - 3.4 6.7 8.3 8.7 5.3 8.4 1.5 1 1 0 1 1 1 0 Protein family of FAM222A p450 PF00067.22 EPE24312.1 - 5.1e-25 88.1 0.0 7.2e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 EPE24313.1 - 7.3e-10 38.9 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE24313.1 - 1.3e-09 38.6 0.0 2.8e-08 34.4 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE24313.1 - 8.3e-08 32.9 0.0 6.4e-07 30.0 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE24313.1 - 7.1e-06 26.6 0.0 4e-05 24.2 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE24313.1 - 0.00012 21.9 0.0 0.00071 19.4 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Abhydrolase_6 PF12697.7 EPE24314.1 - 1.8e-15 58.1 0.1 2.3e-15 57.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EPE24314.1 - 0.019 14.8 0.0 0.11 12.3 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE24314.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Methyltransf_25 PF13649.6 EPE24315.1 - 1.1e-05 26.1 0.0 0.00023 21.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE24315.1 - 3e-05 23.9 0.0 6.9e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE24315.1 - 0.00011 22.9 0.0 0.001 19.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE24315.1 - 0.00012 21.9 0.0 0.0054 16.5 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain NodS PF05401.11 EPE24315.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_11 PF08241.12 EPE24315.1 - 0.038 14.6 0.0 0.11 13.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_PK PF05891.12 EPE24315.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase GDP_Man_Dehyd PF16363.5 EPE24317.1 - 2e-50 172.1 0.0 3.3e-50 171.4 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EPE24317.1 - 1.3e-48 165.5 0.0 1.7e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE24317.1 - 2e-15 56.5 0.0 6e-15 55.0 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EPE24317.1 - 6.5e-13 48.5 0.0 1.9e-11 43.7 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EPE24317.1 - 1.3e-11 44.1 0.0 1.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EPE24317.1 - 2.9e-09 37.1 0.0 4.7e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EPE24317.1 - 6.4e-09 35.6 0.0 9.4e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EPE24317.1 - 3.9e-05 22.9 0.0 0.00052 19.3 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 EPE24317.1 - 0.0013 18.3 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.14 EPE24317.1 - 0.016 14.8 0.1 0.031 13.8 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 EPE24317.1 - 0.059 12.9 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family RPE65 PF03055.15 EPE24317.1 - 0.16 11.1 0.0 3.1 6.9 0.0 2.0 2 0 0 2 2 2 0 Retinal pigment epithelial membrane protein Sad1_UNC PF07738.13 EPE24319.1 - 1.2e-09 38.3 0.1 4.3e-08 33.2 0.0 2.7 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal Cas_TM1802 PF09484.10 EPE24319.1 - 0.062 12.0 1.4 0.1 11.3 1.4 1.3 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) Med9 PF07544.13 EPE24319.1 - 0.16 12.1 0.7 0.49 10.5 0.7 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 AT_hook PF02178.19 EPE24319.1 - 0.68 10.0 3.1 1.7 8.7 3.1 1.8 1 0 0 1 1 1 0 AT hook motif HMG_box PF00505.19 EPE24319.1 - 2.4 8.6 6.0 3.7 8.1 0.4 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box DEAD PF00270.29 EPE24320.1 - 3.2e-47 160.5 0.1 6.2e-47 159.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE24320.1 - 1.4e-24 86.5 0.0 7.8e-24 84.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EPE24320.1 - 1.6e-20 73.0 0.0 4.5e-20 71.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EPE24320.1 - 7.7e-08 32.5 0.2 2.7e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EPE24320.1 - 0.6 9.4 0.0 0.6 9.4 0.0 3.7 3 1 1 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit PAPS_reduct PF01507.19 EPE24321.1 - 4.1e-29 101.8 0.0 1.5e-19 70.7 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family MFS_1 PF07690.16 EPE24323.1 - 1.7e-52 178.5 51.2 9.5e-47 159.6 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPE24323.1 - 2e-13 49.7 22.4 1e-08 34.2 4.0 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EPE24323.1 - 8.4e-09 34.8 10.9 0.00034 19.6 3.5 3.3 2 1 1 3 3 3 3 MFS_1 like family OATP PF03137.20 EPE24323.1 - 6e-08 31.4 3.5 3e-07 29.1 0.5 2.8 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 EPE24323.1 - 1.2e-05 24.8 19.2 3.3e-05 23.4 5.6 2.4 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 EPE24323.1 - 0.62 8.4 11.6 0.015 13.7 3.6 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector DEAD PF00270.29 EPE24324.1 - 1.7e-48 164.7 0.0 3.3e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE24324.1 - 4.1e-24 85.0 0.0 1.3e-22 80.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EPE24324.1 - 1.1e-21 76.8 4.1 4.5e-21 74.9 4.1 2.1 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Pro-kuma_activ PF09286.11 EPE24325.1 - 1.2e-44 152.1 0.2 2.7e-44 150.9 0.2 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain RPA_C PF08784.11 EPE24326.1 - 7.2e-22 78.0 3.7 9.6e-22 77.6 0.2 2.2 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EPE24326.1 - 5.3e-05 23.1 0.1 0.00014 21.8 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Acetyltransf_10 PF13673.7 EPE24327.1 - 1.9e-06 27.8 0.1 3.1e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE24327.1 - 4.6e-06 27.0 0.2 8.6e-06 26.1 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE24327.1 - 1.4e-05 25.3 0.1 2.4e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EPE24327.1 - 0.001 19.1 0.5 0.027 14.5 0.2 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain SGTA_dimer PF16546.5 EPE24327.1 - 0.18 11.6 0.2 0.39 10.5 0.2 1.5 1 0 0 1 1 1 0 Homodimerisation domain of SGTA NUDIX PF00293.28 EPE24328.1 - 4.7e-26 91.4 0.0 6.8e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain HEAT PF02985.22 EPE24329.1 - 3.8e-05 23.6 0.3 2.4 8.7 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat Arm PF00514.23 EPE24329.1 - 0.0074 16.3 4.5 1.5 9.0 0.1 3.6 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EPE24329.1 - 0.013 15.9 0.6 8.1 6.9 0.0 3.3 3 0 0 3 3 3 0 HEAT repeats CNDH2_C PF16858.5 EPE24329.1 - 0.02 14.8 0.6 0.068 13.0 0.3 1.9 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Apo-CIII PF05778.12 EPE24329.1 - 0.042 13.5 0.3 0.1 12.2 0.3 1.7 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Vac14_Fab1_bd PF12755.7 EPE24329.1 - 0.043 14.4 0.0 6.1 7.5 0.0 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EPE24329.1 - 0.1 12.8 0.5 1.9 8.7 0.2 2.9 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TAF6_C PF07571.13 EPE24329.1 - 0.11 12.9 0.0 0.46 10.9 0.0 2.2 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain Arm_2 PF04826.13 EPE24329.1 - 0.14 11.6 1.8 6.8 6.1 0.4 2.3 2 0 0 2 2 2 0 Armadillo-like Nop14 PF04147.12 EPE24329.1 - 6.3 4.9 9.7 14 3.8 9.7 1.5 1 0 0 1 1 1 0 Nop14-like family COA2 PF17051.5 EPE24330.1 - 8.4e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 Metallophos PF00149.28 EPE24331.1 - 1.1e-31 111.0 0.0 4.8e-22 79.5 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EPE24331.1 - 0.032 14.7 0.1 0.089 13.3 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Inhibitor_I36 PF03995.13 EPE24332.1 - 0.0059 16.5 0.3 0.021 14.8 0.3 1.9 1 0 0 1 1 1 1 Peptidase inhibitor family I36 EssA PF10661.9 EPE24333.1 - 0.22 11.3 0.5 0.46 10.3 0.3 1.6 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA FOXP-CC PF16159.5 EPE24333.1 - 0.23 12.1 1.5 0.38 11.4 0.5 1.9 2 0 0 2 2 2 0 FOXP coiled-coil domain Retinal PF15449.6 EPE24333.1 - 0.72 7.6 18.3 0.85 7.3 18.3 1.0 1 0 0 1 1 1 0 Retinal protein FCH PF00611.23 EPE24334.1 - 0.0026 18.0 2.9 0.04 14.2 3.9 2.4 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Csm1_N PF18504.1 EPE24334.1 - 0.0064 16.8 1.1 0.0064 16.8 1.1 2.6 2 1 0 2 2 2 1 Csm1 N-terminal domain DnaJ PF00226.31 EPE24335.1 - 1e-13 51.2 1.2 2.1e-13 50.2 0.2 2.1 2 0 0 2 2 2 1 DnaJ domain ADH_zinc_N PF00107.26 EPE24337.1 - 3.2e-26 91.8 0.5 6.4e-26 90.9 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE24337.1 - 7.4e-16 59.4 0.0 1.9e-15 58.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE24337.1 - 0.0033 17.3 0.6 0.04 13.8 0.0 2.5 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 EPE24337.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain PALP PF00291.25 EPE24337.1 - 0.073 12.5 0.6 0.31 10.4 0.0 2.0 2 1 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Fungal_trans PF04082.18 EPE24338.1 - 6.5e-25 87.7 0.0 1.8e-24 86.2 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 EPE24338.1 - 0.046 12.5 0.0 0.046 12.5 0.0 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain Pol_alpha_B_N PF08418.10 EPE24338.1 - 1.6 8.6 6.6 3.3 7.6 6.6 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Fungal_trans PF04082.18 EPE24340.1 - 2e-44 151.7 0.0 3e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE24340.1 - 7.3e-09 35.6 7.9 1.5e-08 34.6 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1844 PF08899.11 EPE24340.1 - 0.069 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) MFS_1 PF07690.16 EPE24341.1 - 5.3e-46 157.2 18.1 5.3e-46 157.2 18.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE24341.1 - 9.8e-14 51.0 0.6 9.8e-14 51.0 0.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EPE24341.1 - 4.8e-05 22.0 1.8 7.8e-05 21.3 1.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EPE24341.1 - 0.0014 17.1 0.7 0.0022 16.5 0.7 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector SdpI PF13630.6 EPE24341.1 - 0.96 9.6 0.0 0.96 9.6 0.0 3.2 3 0 0 3 3 3 0 SdpI/YhfL protein family OATP PF03137.20 EPE24341.1 - 1.3 7.2 5.0 0.93 7.7 1.0 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pyr_redox_2 PF07992.14 EPE24342.1 - 2.8e-21 76.0 0.0 9.3e-17 61.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EPE24342.1 - 2e-12 46.3 0.4 1.2e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EPE24342.1 - 1.1e-10 41.3 0.0 5.6e-08 32.4 0.0 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE24342.1 - 1.2e-08 35.1 0.0 1.3e-06 28.5 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EPE24342.1 - 5.1e-08 32.4 0.2 3.1e-06 26.6 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EPE24342.1 - 4.2e-05 23.6 0.9 4 7.4 0.0 4.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 EPE24342.1 - 5.2e-05 23.7 0.0 0.082 13.5 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE24342.1 - 0.005 16.0 0.0 0.0097 15.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EPE24342.1 - 0.01 15.0 0.2 4.8 6.2 0.0 3.3 3 1 0 3 3 3 0 Glucose inhibited division protein A DAO PF01266.24 EPE24342.1 - 0.013 15.1 0.7 3.2 7.2 0.1 3.4 2 1 1 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EPE24342.1 - 0.014 14.2 0.5 1.7 7.2 0.1 3.4 4 0 0 4 4 4 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EPE24342.1 - 0.019 14.3 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EPE24342.1 - 0.025 13.8 1.5 0.22 10.8 0.2 2.4 3 0 0 3 3 3 0 Thi4 family NAD_binding_7 PF13241.6 EPE24342.1 - 0.05 14.0 0.0 11 6.5 0.0 2.6 3 0 0 3 3 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EPE24342.1 - 0.25 10.5 2.3 0.33 10.2 0.1 2.2 3 0 0 3 3 3 0 FAD binding domain tRNA_bind PF01588.20 EPE24343.1 - 2.7e-21 75.5 1.1 4.9e-21 74.6 0.2 2.0 2 1 0 2 2 2 1 Putative tRNA binding domain GST_C_2 PF13410.6 EPE24343.1 - 0.0093 16.0 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EPE24343.1 - 0.011 16.0 0.5 0.046 13.9 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF3435 PF11917.8 EPE24344.1 - 9.1e-21 74.3 0.1 1.3e-20 73.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2_4 PF13894.6 EPE24344.1 - 0.04 14.7 9.1 21 6.3 0.2 6.0 5 0 0 5 5 5 0 C2H2-type zinc finger DUF3375 PF11855.8 EPE24345.1 - 0.01 14.8 1.0 2 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) Pyridox_oxase_2 PF12766.7 EPE24346.1 - 6.5e-23 81.2 0.0 1.1e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1581 PF07619.11 EPE24349.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) HATPase_c PF02518.26 EPE24350.1 - 3e-25 88.9 0.0 6.9e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPE24350.1 - 1.2e-19 70.6 0.3 2.5e-19 69.5 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPE24350.1 - 4.7e-08 33.0 0.2 3e-07 30.4 0.2 2.4 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 EPE24350.1 - 8.4e-06 25.8 0.0 2.5e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EPE24350.1 - 1.1e-05 25.3 0.0 4e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 EPE24350.1 - 2.2e-05 24.7 0.2 0.00028 21.1 0.0 3.1 5 0 0 5 5 5 1 PAS domain GAF_2 PF13185.6 EPE24350.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 GAF domain PAS_4 PF08448.10 EPE24350.1 - 0.024 14.9 0.0 0.29 11.4 0.0 2.8 2 0 0 2 2 2 0 PAS fold GAF_3 PF13492.6 EPE24350.1 - 0.064 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 GAF domain PAS_3 PF08447.12 EPE24350.1 - 0.077 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 PAS fold ADH_N PF08240.12 EPE24351.1 - 1.4e-09 37.8 0.0 3.1e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE24351.1 - 5.8e-08 32.8 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Snf7 PF03357.21 EPE24352.1 - 2e-17 63.3 10.5 2e-17 63.3 10.5 2.2 1 1 1 2 2 2 1 Snf7 BLM_N PF16202.5 EPE24352.1 - 0.047 12.8 9.3 0.077 12.1 9.3 1.5 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein Lipoprotein_20 PF13942.6 EPE24352.1 - 0.79 9.6 10.5 1.4 8.8 3.0 2.6 2 0 0 2 2 2 0 YfhG lipoprotein SpoVR PF04293.13 EPE24352.1 - 2.3 6.8 8.3 3.5 6.2 8.3 1.3 1 0 0 1 1 1 0 SpoVR like protein DUF4775 PF16001.5 EPE24352.1 - 5.1 6.4 26.2 1.4 8.3 21.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4775) DUF3391 PF11871.8 EPE24352.1 - 8.7 6.9 20.8 6.5 7.3 2.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) zf-C3HC4_2 PF13923.6 EPE24353.1 - 3.6e-10 39.5 16.7 2.6e-09 36.8 12.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE24353.1 - 8e-08 32.0 13.8 8e-08 32.0 13.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPE24353.1 - 1e-07 31.7 14.2 8.2e-07 28.8 10.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE24353.1 - 6.4e-07 29.2 17.3 1.2e-06 28.4 13.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EPE24353.1 - 1.4e-06 28.2 11.3 1.4e-06 28.2 11.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EPE24353.1 - 1.4e-05 24.8 14.4 0.0015 18.4 10.7 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EPE24353.1 - 3.4e-05 24.1 18.4 5.3e-05 23.5 12.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.6 EPE24353.1 - 0.00011 22.0 5.8 0.00025 20.9 5.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 EPE24353.1 - 0.00087 19.5 6.3 0.00087 19.5 6.3 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EPE24353.1 - 0.0012 19.0 13.2 0.0012 19.0 13.2 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EPE24353.1 - 0.0022 17.7 6.1 0.0022 17.7 6.1 2.8 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-WRNIP1_ubi PF18279.1 EPE24353.1 - 0.11 13.2 1.1 4 8.3 0.0 3.6 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Mob_synth_C PF06463.13 EPE24353.1 - 0.12 12.3 3.9 0.37 10.7 3.9 1.8 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-ANAPC11 PF12861.7 EPE24353.1 - 0.28 11.3 5.2 0.14 12.2 2.7 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EPE24353.1 - 2.2 8.5 13.5 0.7 10.1 10.1 1.9 2 0 0 2 2 1 0 zinc RING finger of MSL2 DUF1272 PF06906.11 EPE24353.1 - 5.5 7.2 13.1 1 9.5 8.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) CDC27 PF09507.10 EPE24354.1 - 5.8e-92 309.3 25.0 7e-92 309.0 25.0 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DEAD PF00270.29 EPE24355.1 - 1.5e-41 142.1 0.1 2.5e-41 141.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE24355.1 - 2.5e-21 76.1 0.0 8e-21 74.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EPE24355.1 - 2.3e-16 59.8 0.0 4.8e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EPE24355.1 - 6.2e-07 29.6 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EPE24355.1 - 0.047 12.9 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 EPE24355.1 - 0.069 11.8 0.6 0.11 11.2 0.0 1.5 2 0 0 2 2 2 0 SNF2 family N-terminal domain Pantoate_ligase PF02569.15 EPE24356.1 - 5.3e-92 307.8 0.0 6.3e-92 307.6 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Fungal_trans PF04082.18 EPE24357.1 - 1.2e-05 24.5 0.2 2.4e-05 23.5 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain RSN1_7TM PF02714.15 EPE24358.1 - 8e-92 307.4 23.1 8e-92 307.4 23.1 2.8 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EPE24358.1 - 1.1e-41 142.2 0.2 1.1e-41 142.2 0.2 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EPE24358.1 - 7.5e-36 124.0 0.0 1.8e-35 122.8 0.0 1.6 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EPE24358.1 - 4e-33 113.4 0.1 1.3e-32 111.8 0.1 1.8 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter kleA_kleC PF17383.2 EPE24358.1 - 0.017 15.4 0.3 0.04 14.2 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A SLATT_3 PF18184.1 EPE24358.1 - 0.14 12.3 0.1 0.6 10.2 0.1 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 Git3 PF11710.8 EPE24359.1 - 4.2e-74 248.7 18.1 4.2e-74 248.7 18.1 1.9 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EPE24359.1 - 1.6e-23 82.6 0.7 1.6e-23 82.6 0.7 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 EPE24359.1 - 1.1e-06 28.2 0.3 1.5e-06 27.7 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) STE3 PF02076.15 EPE24359.1 - 0.00013 21.3 7.6 0.00013 21.3 7.6 1.9 2 0 0 2 2 2 1 Pheromone A receptor DHHA2 PF02833.14 EPE24361.1 - 3e-36 124.8 0.0 3.5e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EPE24362.1 - 3.4e-10 40.1 0.0 5.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 DHH family NAD_binding_4 PF07993.12 EPE24363.1 - 4.6e-21 75.1 0.0 7.1e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EPE24363.1 - 2.3e-20 72.6 0.0 4e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EPE24363.1 - 3.2e-08 33.3 0.0 4.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EPE24363.1 - 1.4e-06 28.5 0.0 6.6e-06 26.4 0.0 2.2 3 0 0 3 3 3 1 Phosphopantetheine attachment site DHQ_synthase PF01761.20 EPE24364.1 - 3.7e-53 180.4 0.0 5.2e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EPE24364.1 - 4.4e-13 49.5 0.0 7.7e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_24 PF13578.6 EPE24365.1 - 2.1e-10 41.6 0.0 3.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EPE24365.1 - 1.5e-09 37.4 0.0 2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase SIS_2 PF13580.6 EPE24365.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 SIS domain MOR2-PAG1_N PF14222.6 EPE24367.1 - 7.2e-227 754.7 0.0 1.4e-226 753.8 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EPE24367.1 - 1.1e-95 320.4 0.1 6.1e-95 317.9 0.0 2.4 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EPE24367.1 - 1.5e-34 118.9 12.0 1.2e-14 53.1 0.1 4.1 3 1 1 4 4 4 4 Cell morphogenesis central region HEAT_EZ PF13513.6 EPE24367.1 - 0.16 12.5 0.6 70 4.1 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat FAD_binding_1 PF00667.20 EPE24368.1 - 2.8e-62 210.2 0.0 4.6e-62 209.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EPE24368.1 - 1.2e-34 119.6 0.6 2.9e-34 118.3 0.6 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EPE24368.1 - 5.8e-22 78.4 0.0 9.2e-21 74.5 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EPE24368.1 - 0.061 13.6 0.1 0.76 10.0 0.0 2.4 1 1 1 2 2 2 0 Flavodoxin domain RRM_1 PF00076.22 EPE24369.1 - 2.5e-23 81.7 0.0 1.8e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RIO1 PF01163.22 EPE24370.1 - 7.4e-42 143.1 0.1 4e-40 137.4 0.1 2.2 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 EPE24370.1 - 3.6e-30 104.0 0.0 9e-30 102.7 0.0 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EPE24370.1 - 1.4e-07 31.7 0.1 0.0022 18.0 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EPE24370.1 - 6.8e-06 25.6 0.1 0.00085 18.7 0.1 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sporozoite_P67 PF05642.11 EPE24370.1 - 0.03 12.4 5.3 0.041 12.0 5.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_Ag35 PF03286.14 EPE24370.1 - 0.15 11.8 4.1 0.24 11.2 4.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 EPE24370.1 - 0.53 8.5 5.1 0.74 8.0 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EPE24370.1 - 1.3 8.3 9.1 1.9 7.7 9.1 1.1 1 0 0 1 1 1 0 NOA36 protein RPN1_RPN2_N PF17781.1 EPE24371.1 - 6e-113 377.3 3.2 1.1e-112 376.5 3.2 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EPE24371.1 - 1.7e-29 101.6 0.1 2.9e-29 100.8 0.1 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EPE24371.1 - 7.3e-23 79.8 19.2 6.4e-07 29.5 0.3 9.6 10 0 0 10 10 10 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EPE24371.1 - 5.1e-11 42.8 1.1 2.9e-05 24.3 0.0 4.9 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 EPE24371.1 - 0.048 13.9 0.0 3.3 8.2 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat SUKH_6 PF14568.6 EPE24371.1 - 0.12 12.8 0.0 2.9 8.4 0.0 2.8 3 0 0 3 3 3 0 SMI1-KNR4 cell-wall DUF3848 PF12959.7 EPE24371.1 - 0.15 12.1 2.8 1.4 9.0 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3848) Mlh1_C PF16413.5 EPE24372.1 - 3.1e-98 328.5 0.0 5.7e-98 327.6 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EPE24372.1 - 5.1e-33 113.3 0.1 9.1e-33 112.5 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EPE24372.1 - 5.1e-14 52.3 0.0 1.3e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EPE24372.1 - 1.9e-06 28.3 0.0 5.6e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GMC_oxred_N PF00732.19 EPE24373.1 - 3.7e-48 164.4 0.0 8.3e-47 160.0 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE24373.1 - 8.1e-19 68.6 0.0 1.6e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EPE24373.1 - 8.5e-05 22.7 0.1 0.00023 21.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE24373.1 - 0.0018 17.9 2.1 0.0019 17.9 0.3 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EPE24373.1 - 0.012 14.7 0.1 0.017 14.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EPE24373.1 - 0.013 14.7 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EPE24373.1 - 0.024 13.7 0.0 0.12 11.5 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain MatE PF01554.18 EPE24374.1 - 3.7e-58 195.7 25.6 1.3e-32 112.7 6.6 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EPE24374.1 - 0.0012 18.9 7.8 0.0012 18.9 7.8 3.4 2 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain PRKCSH_1 PF13015.6 EPE24374.1 - 0.23 11.2 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein DUF202 PF02656.15 EPE24375.1 - 2.2e-16 60.1 0.6 8.2e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) HMw1_D2 PF18254.1 EPE24375.1 - 0.054 13.8 0.0 0.094 13.1 0.0 1.3 1 0 0 1 1 1 0 HMW1 domain 2 COX4_pro_2 PF07835.12 EPE24375.1 - 0.14 12.3 0.0 0.14 12.3 0.0 1.9 3 0 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV SH3_1 PF00018.28 EPE24376.1 - 3.7e-27 93.7 0.0 6.4e-13 48.1 0.0 2.9 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 EPE24376.1 - 1.7e-15 56.6 0.1 5.1e-07 29.4 0.1 2.9 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 EPE24376.1 - 3.2e-14 52.9 0.0 5.8e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 EPE24376.1 - 1.9e-11 43.5 0.0 8e-08 31.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 EPE24376.1 - 7.9e-06 25.7 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 PB1 domain INTAP PF16617.5 EPE24376.1 - 0.014 15.7 2.0 0.047 14.0 2.0 1.8 1 0 0 1 1 1 0 Intersectin and clathrin adaptor AP2 binding region SPX PF03105.19 EPE24376.1 - 0.025 14.5 5.4 0.063 13.2 5.4 1.5 1 1 0 1 1 1 0 SPX domain DBD_Tnp_Mut PF03108.15 EPE24377.1 - 1.9e-10 40.6 0.2 4.9e-10 39.3 0.2 1.7 1 0 0 1 1 1 1 MuDR family transposase DUF1996 PF09362.10 EPE24378.1 - 4.3e-46 157.8 1.0 5.2e-46 157.5 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SAC3_GANP PF03399.16 EPE24379.1 - 6.9e-27 94.6 1.1 7e-25 88.0 1.1 2.2 1 1 0 1 1 1 1 SAC3/GANP family DIX PF00778.17 EPE24379.1 - 0.13 12.1 0.1 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 DIX domain EAP30 PF04157.16 EPE24380.1 - 2.9e-42 144.6 0.0 3.7e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 EPE24380.1 - 9.8e-24 83.4 0.0 1.6e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 EPE24380.1 - 2.4e-20 71.7 1.8 2.4e-20 71.7 1.8 3.2 3 1 0 3 3 3 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EPE24380.1 - 0.00012 22.1 3.7 0.0022 18.0 0.4 2.6 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger GRAM PF02893.20 EPE24380.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 GRAM domain zf-RanBP PF00641.18 EPE24380.1 - 0.043 13.1 8.3 0.24 10.8 1.3 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DZR PF12773.7 EPE24380.1 - 0.67 10.0 3.6 0.49 10.5 0.4 2.1 2 0 0 2 2 2 0 Double zinc ribbon FYVE PF01363.21 EPE24381.1 - 0.0016 18.5 0.4 0.0025 17.9 0.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-RING_UBOX PF13445.6 EPE24381.1 - 0.0035 17.4 0.5 0.0086 16.1 0.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EPE24381.1 - 0.016 15.1 0.7 0.016 15.1 0.7 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SKG6 PF08693.10 EPE24382.1 - 0.0035 16.7 0.3 0.0064 15.9 0.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF2964 PF11177.8 EPE24382.1 - 0.027 14.7 0.3 0.039 14.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) PRIMA1 PF16101.5 EPE24382.1 - 0.031 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF3377 PF11857.8 EPE24382.1 - 0.045 13.7 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Herpes_gE PF02480.16 EPE24382.1 - 0.15 10.8 0.0 0.16 10.7 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RAMP4 PF06624.12 EPE24382.1 - 1.3 9.1 4.6 0.74 9.9 2.0 1.9 1 1 1 2 2 2 0 Ribosome associated membrane protein RAMP4 Tnp_zf-ribbon_2 PF13842.6 EPE24383.1 - 1.3 9.9 8.5 2.5 9.0 8.5 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon NAD_binding_4 PF07993.12 EPE24385.1 - 2.9e-31 108.6 0.0 4.6e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EPE24385.1 - 1.4e-25 89.8 0.0 2.4e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EPE24385.1 - 1.4e-07 31.2 0.0 2.6e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EPE24385.1 - 0.00013 22.2 0.0 0.00029 21.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 EPE24385.1 - 0.015 15.2 0.4 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 EPE24385.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EPE24385.1 - 0.17 10.9 0.0 2.7 7.0 0.0 2.4 3 0 0 3 3 3 0 RmlD substrate binding domain Sec7 PF01369.20 EPE24386.1 - 2.3e-70 236.0 3.0 8.9e-70 234.1 0.2 3.0 3 0 0 3 3 3 1 Sec7 domain DUF1981 PF09324.10 EPE24386.1 - 7.6e-33 112.2 8.3 5.2e-32 109.5 0.1 5.1 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 EPE24386.1 - 7.6e-27 94.2 7.9 2e-25 89.6 1.1 3.7 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EPE24386.1 - 5.1e-23 81.6 4.4 3.2e-21 75.8 0.3 3.6 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 2-oxoacid_dh PF00198.23 EPE24387.1 - 1.1e-71 241.0 0.0 1.3e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EPE24387.1 - 3.5e-18 65.2 0.7 3.5e-18 65.2 0.7 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 EPE24387.1 - 1.1e-05 25.7 0.5 2.8e-05 24.4 0.5 1.7 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 EPE24387.1 - 0.5 10.9 0.0 0.5 10.9 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) CHCH PF06747.13 EPE24388.1 - 1.9e-07 31.0 2.2 3.8e-07 30.1 2.2 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EPE24388.1 - 0.0015 18.9 2.8 0.0046 17.3 2.8 1.9 1 0 0 1 1 1 1 GCK domain TPK_catalytic PF04263.16 EPE24389.1 - 1.2e-31 109.3 0.0 1.7e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EPE24389.1 - 2.2e-20 72.1 0.3 3.5e-20 71.5 0.3 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Fer4_10 PF13237.6 EPE24391.1 - 1.2 9.3 5.8 3 8.0 5.8 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 EPE24391.1 - 5.5 7.3 7.7 1.4 9.2 2.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Porph_ging PF09697.10 EPE24392.1 - 0.095 13.2 1.8 0.12 12.9 1.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (Porph_ging) Cytochrom_c3_2 PF14537.6 EPE24394.1 - 0.19 12.2 4.4 3.9 8.0 1.8 2.5 2 0 0 2 2 2 0 Cytochrome c3 Rad4 PF03835.15 EPE24395.1 - 8.8e-28 96.8 0.2 3e-27 95.1 0.2 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EPE24395.1 - 5.8e-25 87.5 0.1 1.2e-24 86.5 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EPE24395.1 - 1.3e-18 66.6 0.3 2.7e-18 65.5 0.3 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EPE24395.1 - 9.4e-13 48.9 0.6 9.4e-13 48.9 0.6 4.4 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EPE24395.1 - 0.033 14.6 0.0 0.092 13.2 0.0 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily Acid_PPase PF12689.7 EPE24396.1 - 2.3e-67 226.1 0.0 2.7e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase PF00702.26 EPE24396.1 - 0.16 12.3 0.1 4.6 7.5 0.0 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Acetyltransf_10 PF13673.7 EPE24397.1 - 4.2e-12 46.1 0.0 6e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE24397.1 - 9.2e-12 45.2 0.0 1.3e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE24397.1 - 1.4e-11 44.7 0.0 1.9e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EPE24397.1 - 6.9e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EPE24397.1 - 2e-05 24.5 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EPE24397.1 - 6.8e-05 23.0 0.0 0.00011 22.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EPE24397.1 - 0.05 13.8 0.0 0.08 13.1 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.6 EPE24398.1 - 6.7e-45 153.7 57.4 1.6e-43 149.1 57.4 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE24398.1 - 5e-21 74.8 49.5 9.5e-20 70.6 49.5 2.0 1 1 0 1 1 1 1 Amino acid permease Herpes_UL47 PF03362.13 EPE24398.1 - 0.096 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL47 protein adh_short PF00106.25 EPE24399.1 - 4.8e-21 75.1 0.1 5.8e-21 74.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE24399.1 - 3.7e-17 62.7 0.1 4.7e-17 62.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE24399.1 - 4.3e-05 23.5 0.8 5.6e-05 23.1 0.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE24399.1 - 0.0017 17.9 0.2 0.0031 17.0 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FYVE PF01363.21 EPE24400.1 - 6.3e-23 80.7 27.7 4.3e-17 62.0 8.2 3.1 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 EPE24400.1 - 1.1e-16 60.3 0.3 2.7e-16 59.0 0.3 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 EPE24400.1 - 7.8e-05 22.8 2.4 7.8e-05 22.8 2.4 4.3 5 1 1 6 6 6 1 AN1-like Zinc finger zf-Di19 PF05605.12 EPE24400.1 - 0.0061 16.8 0.1 0.0061 16.8 0.1 2.9 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 EPE24400.1 - 0.038 14.3 11.0 0.14 12.5 0.0 3.5 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) GAGA PF09237.11 EPE24400.1 - 0.11 12.3 0.3 0.62 9.9 0.0 2.4 2 0 0 2 2 2 0 GAGA factor zf-WRNIP1_ubi PF18279.1 EPE24400.1 - 0.12 13.1 4.9 1.9 9.3 0.2 3.1 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain UBZ_FAAP20 PF15750.5 EPE24400.1 - 0.45 10.5 6.0 5.7 7.0 0.4 3.4 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zf-ribbon_3 PF13248.6 EPE24400.1 - 2.1 7.8 10.0 4.5 6.8 0.6 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_9 PF16293.5 EPE24400.1 - 4.5 7.2 5.4 22 5.0 0.0 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-met PF12874.7 EPE24400.1 - 5.5 7.5 18.1 0.16 12.4 0.6 5.0 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Trimer_CC PF08954.11 EPE24400.1 - 8.1 6.1 7.5 2.3 7.9 0.4 3.2 3 0 0 3 3 3 0 Trimerisation motif zf-C2H2_4 PF13894.6 EPE24400.1 - 9.8 7.3 32.8 2.2 9.3 0.1 6.0 5 1 1 6 6 6 0 C2H2-type zinc finger NAD_binding_7 PF13241.6 EPE24401.1 - 1.4e-32 112.3 0.0 2.7e-32 111.3 0.0 1.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EPE24401.1 - 2.7e-27 94.2 0.0 4e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EPE24401.1 - 5.4e-13 48.1 0.1 1.1e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 EPE24401.1 - 0.0013 18.0 0.0 0.0017 17.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EPE24401.1 - 0.03 14.4 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EPE24401.1 - 0.038 14.3 0.1 0.078 13.2 0.1 1.5 1 1 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 EPE24401.1 - 0.1 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 EPE24401.1 - 0.14 11.5 1.5 0.63 9.3 0.1 2.1 1 1 1 2 2 2 0 ThiF family Semialdhyde_dh PF01118.24 EPE24401.1 - 0.14 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SUR7 PF06687.12 EPE24402.1 - 5.4e-31 107.9 3.1 6.5e-31 107.6 3.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EPE24402.1 - 0.00029 20.8 1.4 0.00029 20.8 1.4 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Phage_holin_5_2 PF16079.5 EPE24402.1 - 1.8 9.0 5.3 0.53 10.6 0.2 2.5 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V ParA PF10609.9 EPE24404.1 - 2.2e-96 322.1 0.0 2.6e-96 321.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EPE24404.1 - 4.4e-09 36.5 0.0 1.1e-08 35.1 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EPE24404.1 - 1.1e-05 25.5 0.1 8.4e-05 22.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EPE24404.1 - 8.7e-05 21.8 1.1 0.0009 18.5 0.5 2.4 1 1 2 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.6 EPE24404.1 - 0.00041 20.0 0.0 0.00073 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 EPE24404.1 - 0.0018 18.2 0.1 0.19 11.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EPE24404.1 - 0.0071 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 EPE24404.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Fer4_NifH PF00142.18 EPE24404.1 - 0.014 14.9 0.0 0.75 9.2 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 EPE24404.1 - 0.018 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase MipZ PF09140.11 EPE24404.1 - 0.021 14.1 0.0 0.043 13.1 0.0 1.5 1 1 0 1 1 1 0 ATPase MipZ T2SSE PF00437.20 EPE24404.1 - 0.023 13.7 0.2 0.035 13.2 0.2 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein DnaB_C PF03796.15 EPE24404.1 - 0.057 12.7 0.0 0.21 10.9 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RNA_helicase PF00910.22 EPE24404.1 - 0.086 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase CBP_BcsQ PF06564.12 EPE24404.1 - 0.093 12.2 0.1 2 7.9 0.1 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ VirE PF05272.11 EPE24404.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E TsaE PF02367.17 EPE24404.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EPE24404.1 - 0.16 12.4 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EPE24404.1 - 0.16 11.1 0.1 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 EPE24404.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EPE24404.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain SRP54 PF00448.22 EPE24404.1 - 0.22 11.1 0.2 0.69 9.5 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EPE24404.1 - 0.24 10.6 0.0 0.41 9.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PEMT PF04191.13 EPE24405.1 - 3.8e-58 194.4 11.4 5.3e-36 123.2 2.2 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 EPE24405.1 - 0.031 14.1 0.5 0.083 12.7 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 EPE24405.1 - 0.086 13.4 0.1 0.94 10.1 0.1 2.3 1 1 0 1 1 1 0 SKICH domain DUF5353 PF17304.2 EPE24406.1 - 1.9e-36 123.6 3.8 2.5e-36 123.2 3.8 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) DUF883 PF05957.13 EPE24406.1 - 0.0014 19.2 1.1 0.0028 18.2 1.1 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) CbtA PF09490.10 EPE24406.1 - 0.0077 16.0 0.8 0.011 15.6 0.8 1.2 1 0 0 1 1 1 1 Probable cobalt transporter subunit (CbtA) ISG65-75 PF11727.8 EPE24406.1 - 0.0088 15.3 6.7 0.012 14.9 6.7 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein IER PF05760.12 EPE24406.1 - 0.018 15.4 1.0 0.023 15.0 1.0 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Ndc1_Nup PF09531.10 EPE24406.1 - 0.12 11.0 0.2 0.12 11.0 0.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup YlqD PF11068.8 EPE24406.1 - 0.18 12.2 3.9 0.25 11.7 3.9 1.1 1 0 0 1 1 1 0 YlqD protein Presenilin PF01080.17 EPE24406.1 - 0.67 8.6 1.6 0.73 8.5 1.6 1.1 1 0 0 1 1 1 0 Presenilin Golgin_A5 PF09787.9 EPE24406.1 - 0.74 9.2 6.0 0.93 8.9 6.0 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3987 PF13148.6 EPE24406.1 - 2.7 6.9 6.5 4.1 6.3 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Glycophorin_A PF01102.18 EPE24407.1 - 0.17 12.2 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A GHMP_kinases_N PF00288.26 EPE24408.1 - 1.4e-16 60.5 1.7 3.6e-16 59.1 1.7 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EPE24408.1 - 1.4e-06 28.5 0.0 3.1e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Peptidase_M75 PF09375.10 EPE24408.1 - 0.12 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Imelysin PPR_2 PF13041.6 EPE24409.1 - 1.6e-44 149.9 3.1 1.9e-08 34.4 0.0 13.1 11 3 4 15 15 15 7 PPR repeat family PPR_3 PF13812.6 EPE24409.1 - 1.1e-31 108.7 0.0 0.0038 17.3 0.0 11.2 8 3 4 12 12 12 8 Pentatricopeptide repeat domain PPR PF01535.20 EPE24409.1 - 3.1e-25 86.6 13.9 0.00061 19.9 0.0 14.1 17 0 0 17 17 17 4 PPR repeat PPR_1 PF12854.7 EPE24409.1 - 3.8e-21 74.5 0.2 1.2e-06 28.1 0.0 9.3 11 0 0 11 11 11 3 PPR repeat PPR_long PF17177.4 EPE24409.1 - 6.8e-18 64.8 5.9 1.1e-08 34.7 0.0 6.2 3 2 2 6 6 6 3 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 EPE24409.1 - 0.0054 17.1 0.0 0.076 13.4 0.0 2.8 2 0 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 EPE24409.1 - 0.083 12.7 0.9 15 5.5 0.0 4.0 4 1 0 5 5 5 0 Mitochondrial ATPase expression DUF4551 PF15087.6 EPE24410.1 - 9.9 4.9 9.0 11 4.7 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DDE_3 PF13358.6 EPE24412.1 - 0.033 13.9 0.0 0.091 12.5 0.0 1.7 1 0 0 1 1 1 0 DDE superfamily endonuclease Methyltransf_33 PF10017.9 EPE24413.1 - 1.7e-78 263.9 0.0 2.6e-78 263.3 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EPE24413.1 - 5.8e-18 65.4 0.2 8.8e-17 61.5 0.0 2.5 2 1 0 2 2 2 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EPE24413.1 - 1.5e-05 25.5 0.7 5e-05 23.8 0.7 1.9 1 1 0 1 1 1 1 DinB superfamily Nuf2 PF03800.14 EPE24414.1 - 8.6e-40 136.1 0.2 2.4e-39 134.6 0.2 1.8 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 EPE24414.1 - 6.8e-35 119.6 13.3 6.8e-35 119.6 13.3 4.0 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain Troponin PF00992.20 EPE24414.1 - 0.0058 16.9 14.9 0.0058 16.9 14.9 3.2 2 1 1 3 3 3 1 Troponin ApoC-I PF04691.12 EPE24414.1 - 0.027 14.4 0.6 0.27 11.2 0.6 2.8 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Bacillus_HBL PF05791.11 EPE24414.1 - 1.9 8.3 16.1 0.26 11.1 1.8 3.6 2 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.11 EPE24414.1 - 2.1 7.2 43.3 3.2 6.5 7.0 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein SLATT_6 PF18169.1 EPE24414.1 - 5.2 6.6 6.1 1.1 8.8 0.1 2.5 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 6 CpxA_peri PF16527.5 EPE24414.1 - 5.2 7.4 18.0 2.7 8.4 1.9 3.8 3 1 1 4 4 4 0 Two-component sensor protein CpxA, periplasmic domain IFT46_B_C PF12317.8 EPE24414.1 - 8.4 6.1 10.5 0.81 9.4 2.1 2.7 2 1 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Adaptin_N PF01602.20 EPE24416.1 - 5.5e-108 361.8 0.0 7e-108 361.4 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EPE24416.1 - 2.7e-16 60.1 0.1 8e-15 55.2 0.0 2.9 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EPE24416.1 - 5.7e-11 42.7 0.6 0.00013 22.3 0.0 5.2 3 2 3 6 6 6 4 HEAT repeats HEAT PF02985.22 EPE24416.1 - 1.2e-10 40.6 0.3 0.14 12.5 0.0 6.0 6 0 0 6 6 6 3 HEAT repeat Cohesin_HEAT PF12765.7 EPE24416.1 - 0.0015 18.7 0.0 1.5 9.2 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.6 EPE24416.1 - 0.004 17.6 1.3 5.7 7.6 0.0 4.6 4 0 0 4 4 4 1 HEAT-like repeat VHS PF00790.19 EPE24416.1 - 0.21 11.4 1.0 35 4.2 0.0 3.5 4 0 0 4 4 4 0 VHS domain SDA1 PF05285.12 EPE24416.1 - 3.4 7.0 15.7 5.2 6.4 15.7 1.2 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 EPE24416.1 - 8.8 5.4 8.1 8.8e+02 -1.1 13.1 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Metallophos PF00149.28 EPE24418.1 - 5e-25 89.2 1.7 2.1e-23 83.9 1.7 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EPE24418.1 - 0.025 15.0 0.2 0.064 13.7 0.2 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Rho_GDI PF02115.17 EPE24419.1 - 1.4e-64 217.5 0.7 1.5e-64 217.4 0.7 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Pkinase PF00069.25 EPE24420.1 - 4.1e-67 226.3 0.0 8.5e-67 225.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE24420.1 - 9.4e-31 107.0 0.0 2.5e-29 102.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EPE24420.1 - 0.02 14.5 0.1 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EPE24420.1 - 0.021 14.1 0.2 4.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EPE24420.1 - 0.033 14.1 0.1 0.2 11.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EPE24420.1 - 0.062 12.1 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase DUF3328 PF11807.8 EPE24422.1 - 0.00026 20.8 0.1 0.00051 19.9 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_2 PF13347.6 EPE24423.1 - 9.5e-09 34.3 6.8 9.5e-09 34.3 6.8 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein DUF3328 PF11807.8 EPE24425.1 - 7.6e-22 78.2 3.0 1e-21 77.8 3.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.8 EPE24427.1 - 1.9e-26 92.8 8.9 2.3e-26 92.5 8.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 EPE24428.1 - 5.5e-14 52.2 0.0 1.1e-13 51.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE24428.1 - 0.00062 19.1 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Transp_cyt_pur PF02133.15 EPE24430.1 - 1.3e-16 60.4 37.5 2.1e-16 59.8 37.5 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF5453 PF17534.2 EPE24430.1 - 1.2 9.1 6.9 0.59 10.1 3.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5453) Pec_lyase_C PF00544.19 EPE24431.1 - 3.9e-46 157.3 9.5 5.3e-46 156.9 9.5 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EPE24431.1 - 6.8e-06 26.0 10.2 1.2e-05 25.3 9.8 1.6 1 1 0 1 1 1 1 Right handed beta helix region PPI_Ypi1 PF07491.11 EPE24432.1 - 0.0019 18.0 0.1 0.0048 16.7 0.1 1.7 1 0 0 1 1 1 1 Protein phosphatase inhibitor LPD28 PF18843.1 EPE24432.1 - 0.17 11.6 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 28 Ribonuc_L-PSP PF01042.21 EPE24433.1 - 1.1e-37 128.8 0.0 1.2e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Isochorismatase PF00857.20 EPE24435.1 - 8.5e-29 101.0 0.0 1.7e-28 100.0 0.0 1.5 1 1 0 1 1 1 1 Isochorismatase family DDE_3 PF13358.6 EPE24436.1 - 4.4e-10 39.5 0.0 8.7e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 EPE24436.1 - 0.00017 21.8 0.4 0.00031 20.9 0.4 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 EPE24436.1 - 0.00031 21.3 6.5 0.0023 18.5 0.5 3.3 2 1 1 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.6 EPE24436.1 - 0.11 12.6 1.1 0.2 11.7 0.6 1.8 2 0 0 2 2 2 0 Winged helix-turn helix AbiH PF14253.6 EPE24437.1 - 0.1 12.5 2.4 0.23 11.3 2.4 1.5 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH zinc_ribbon_9 PF14369.6 EPE24437.1 - 0.12 12.7 0.2 0.33 11.3 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon DUF5427 PF10310.9 EPE24438.1 - 1.7e-180 601.0 0.4 1.9e-180 600.8 0.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Ndc1_Nup PF09531.10 EPE24438.1 - 5.5 5.5 6.6 0.57 8.8 2.3 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Clr5 PF14420.6 EPE24439.1 - 4.3e-12 46.1 0.5 1.3e-11 44.6 0.5 1.8 1 0 0 1 1 1 1 Clr5 domain Ank_5 PF13857.6 EPE24439.1 - 6.3e-11 42.3 2.8 0.035 14.4 0.0 5.5 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPE24439.1 - 2.3e-09 37.6 0.1 0.00034 21.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE24439.1 - 2.2e-08 34.6 0.0 0.0015 19.1 0.0 4.4 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE24439.1 - 5.5e-07 29.4 1.0 0.0055 17.1 0.0 5.8 7 0 0 7 7 7 1 Ankyrin repeat Ank PF00023.30 EPE24439.1 - 0.0024 18.3 0.9 0.34 11.4 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat LicD PF04991.13 EPE24440.1 - 1.6e-18 67.7 6.7 7e-14 52.5 3.1 3.4 3 1 1 4 4 4 2 LicD family HC2 PF07382.11 EPE24440.1 - 0.049 13.7 22.5 0.074 13.1 22.5 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Biliv-reduc_cat PF09166.10 EPE24440.1 - 0.059 13.7 1.2 0.1 12.9 0.0 2.1 2 0 0 2 2 2 0 Biliverdin reductase, catalytic GAGA_bind PF06217.12 EPE24440.1 - 0.095 13.0 8.1 0.14 12.4 8.1 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family ANF_receptor PF01094.28 EPE24440.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Mitofilin PF09731.9 EPE24440.1 - 1.5 7.6 23.8 1.9 7.2 23.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Slx4 PF09494.10 EPE24441.1 - 4.5e-25 87.4 0.1 8.7e-25 86.5 0.1 1.5 1 0 0 1 1 1 1 Slx4 endonuclease Ribosomal_S21e PF01249.18 EPE24442.1 - 8.8e-43 144.3 0.0 9.8e-43 144.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e FAD_binding_7 PF03441.14 EPE24443.1 - 3.5e-82 274.8 1.5 5.9e-82 274.1 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EPE24443.1 - 5.6e-39 133.8 0.0 1.1e-38 132.8 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase Usp PF00582.26 EPE24443.1 - 0.012 16.2 0.1 0.029 14.9 0.1 1.6 1 0 0 1 1 1 0 Universal stress protein family Pro_dh PF01619.18 EPE24444.1 - 2.5e-67 227.5 0.0 3e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Proline dehydrogenase Tim17 PF02466.19 EPE24445.1 - 2.7e-06 27.7 3.2 1.3e-05 25.6 3.3 1.8 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF3464 PF11947.8 EPE24445.1 - 0.062 13.1 0.4 0.062 13.1 0.4 2.1 2 1 1 3 3 3 0 Photosynthesis affected mutant 68 Helo_like_N PF17111.5 EPE24448.1 - 1.8e-05 24.2 2.6 7.7e-05 22.2 0.6 2.4 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins AIP3 PF03915.13 EPE24448.1 - 0.06 12.4 0.8 0.1 11.7 0.8 1.4 1 1 0 1 1 1 0 Actin interacting protein 3 SesA PF17107.5 EPE24448.1 - 0.31 11.3 2.9 3.1 8.0 1.1 2.6 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Baculo_PEP_C PF04513.12 EPE24448.1 - 0.77 9.8 7.8 5.2 7.1 1.8 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NUDIX PF00293.28 EPE24450.1 - 0.0017 18.4 0.0 0.0052 16.8 0.0 2.0 1 1 0 1 1 1 1 NUDIX domain Vps53_N PF04100.12 EPE24451.1 - 4.7e-105 351.7 3.5 8.7e-105 350.8 3.5 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 EPE24451.1 - 3.9e-08 32.9 6.9 3.9e-08 32.9 6.9 1.8 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EPE24451.1 - 0.00025 20.9 0.2 0.00065 19.6 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) VPS53_C PF16854.5 EPE24451.1 - 0.0018 18.2 0.1 0.026 14.4 0.0 2.7 2 1 1 3 3 3 1 Vacuolar protein sorting-associated protein 53 C-terminus Spc7 PF08317.11 EPE24451.1 - 0.0024 16.8 6.7 0.0024 16.8 6.7 1.6 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF2939 PF11159.8 EPE24451.1 - 0.016 15.6 0.0 0.21 12.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) DUF3450 PF11932.8 EPE24451.1 - 0.032 13.5 5.9 0.083 12.2 5.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Rbsn PF11464.8 EPE24451.1 - 0.073 12.8 0.1 0.29 10.9 0.1 2.1 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Allexi_40kDa PF05549.11 EPE24451.1 - 1.2 8.6 6.9 1.4 8.4 5.2 1.9 1 1 0 1 1 1 0 Allexivirus 40kDa protein MitMem_reg PF13012.6 EPE24451.1 - 1.3 9.4 0.0 1.3 9.4 0.0 3.7 4 1 0 4 4 4 0 Maintenance of mitochondrial structure and function Phage_GPO PF05929.11 EPE24451.1 - 3.3 7.2 8.9 7.6 6.1 6.3 2.4 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Snapin_Pallidin PF14712.6 EPE24451.1 - 6.5 7.3 12.5 0.68 10.4 3.9 3.4 3 1 1 4 4 4 0 Snapin/Pallidin LETM1 PF07766.13 EPE24453.1 - 1.6e-103 345.7 0.1 1.6e-103 345.7 0.1 1.5 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 EPE24453.1 - 0.0069 16.1 0.0 0.18 11.6 0.0 3.0 3 0 0 3 3 3 1 SAP domain ADK PF00406.22 EPE24454.1 - 1.4e-37 129.2 0.0 1.2e-19 70.9 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 EPE24454.1 - 9.8e-16 58.4 0.0 5.5e-10 39.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain ADK_lid PF05191.14 EPE24454.1 - 6.1e-12 45.3 0.0 1.1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EPE24454.1 - 1.2e-06 29.1 0.0 2.9e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EPE24454.1 - 2.8e-05 24.3 0.0 0.0042 17.3 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EPE24454.1 - 0.025 14.8 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EPE24454.1 - 0.045 14.2 0.0 0.94 9.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EPE24454.1 - 0.059 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EPE24454.1 - 0.18 11.1 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Metallophos PF00149.28 EPE24455.1 - 1.2e-05 25.9 4.1 6.7e-05 23.5 4.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DHHC PF01529.20 EPE24456.1 - 2.7e-32 111.7 7.7 2.7e-32 111.7 7.7 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Cwf_Cwc_15 PF04889.12 EPE24456.1 - 0.94 9.2 11.7 1.8 8.2 0.1 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Spt4 PF06093.13 EPE24456.1 - 1.8 8.7 5.3 3.7 7.7 5.3 1.5 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger MFS_1 PF07690.16 EPE24457.1 - 2.7e-40 138.4 64.5 6.7e-39 133.8 60.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE24457.1 - 3.4e-11 42.7 10.9 3.4e-11 42.7 10.9 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EPE24457.1 - 6.5e-08 31.5 29.1 1.9e-07 29.9 29.1 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Velvet PF11754.8 EPE24458.1 - 0.15 12.0 5.0 0.18 11.7 4.9 1.3 1 1 0 1 1 1 0 Velvet factor Sugar_tr PF00083.24 EPE24459.1 - 1.1e-126 423.3 25.4 1.3e-126 423.1 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE24459.1 - 2.6e-19 69.4 43.2 8.7e-14 51.2 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ilm1 PF10311.9 EPE24459.1 - 0.0045 16.7 1.3 0.0094 15.6 1.3 1.5 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF3165 PF11364.8 EPE24459.1 - 0.022 15.1 0.9 0.022 15.1 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) Glyco_hydro_61 PF03443.14 EPE24460.1 - 8.3e-59 199.0 0.9 1e-58 198.7 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CorA PF01544.18 EPE24461.1 - 5e-10 39.2 1.0 2.2e-09 37.1 1.0 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein p31comet PF06581.12 EPE24461.1 - 0.02 14.0 0.2 0.035 13.3 0.2 1.3 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding Fasciclin PF02469.22 EPE24462.1 - 0.0052 17.0 0.0 0.0071 16.6 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain MafB PF06255.13 EPE24462.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Neisseria toxin MafB Synaptobrevin PF00957.21 EPE24463.1 - 3.3e-14 52.4 0.5 5e-14 51.9 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EPE24463.1 - 5.7e-14 51.9 0.0 1.2e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain NACHT PF05729.12 EPE24464.1 - 0.069 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TPR_14 PF13428.6 EPE24464.1 - 0.083 13.8 0.0 0.2 12.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2958 PF11171.8 EPE24464.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) TPR_14 PF13428.6 EPE24466.1 - 0.022 15.5 0.0 21 6.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPE24466.1 - 0.071 13.8 0.0 16 6.4 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Pyridoxal_deC PF00282.19 EPE24467.1 - 4.8e-106 354.6 0.0 5.7e-106 354.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 EPE24467.1 - 0.02 14.1 0.0 0.06 12.5 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II DUF5040 PF16443.5 EPE24467.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) SMC_Nse1 PF07574.13 EPE24468.1 - 1.2e-50 172.2 0.8 1.7e-50 171.6 0.8 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex NTP_transf_9 PF04248.12 EPE24468.1 - 2.8e-21 75.2 1.8 5.4e-21 74.3 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF427) zf-RING-like PF08746.11 EPE24468.1 - 3.8e-14 52.7 10.8 6.5e-14 52.0 10.8 1.4 1 0 0 1 1 1 1 RING-like domain Phage_int_SAM_4 PF13495.6 EPE24468.1 - 0.0042 17.5 0.5 0.1 13.1 0.1 3.0 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain OAM_alpha PF16552.5 EPE24468.1 - 0.031 14.1 0.0 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit zf-HC5HC2H PF13771.6 EPE24468.1 - 0.058 13.7 2.6 0.12 12.6 2.6 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_2 PF03107.16 EPE24468.1 - 0.58 10.5 5.5 0.47 10.8 1.4 2.4 2 0 0 2 2 2 0 C1 domain Ceramidase_alk PF04734.13 EPE24469.1 - 1e-217 723.8 0.2 1.2e-217 723.6 0.2 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EPE24469.1 - 2.8e-59 199.7 0.2 5e-59 198.9 0.2 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Toxin_29 PF08116.11 EPE24469.1 - 6.8 6.8 5.6 19 5.4 5.5 1.8 1 1 0 1 1 1 0 PhTx neurotoxin family DUF383 PF04063.14 EPE24470.1 - 1.8e-69 233.2 0.5 7.1e-69 231.3 0.1 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EPE24470.1 - 1.9e-21 75.6 4.9 3.8e-21 74.7 3.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF384) FMN_dh PF01070.18 EPE24471.1 - 2.9e-121 404.8 0.1 3.5e-121 404.5 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EPE24471.1 - 6.9e-22 77.4 0.1 1.4e-21 76.4 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EPE24471.1 - 9.5e-08 31.6 0.0 1.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EPE24471.1 - 0.00015 20.9 0.0 0.00038 19.6 0.0 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EPE24471.1 - 0.0031 16.9 0.1 0.0066 15.9 0.1 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 EPE24471.1 - 0.025 14.1 1.0 1.2 8.6 0.1 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein G3P_antiterm PF04309.12 EPE24471.1 - 0.13 11.7 0.0 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 EPE24471.1 - 0.13 11.5 0.0 16 4.7 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Pro_CA PF00484.19 EPE24471.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Carbonic anhydrase ELP6 PF09807.9 EPE24472.1 - 4e-08 33.0 0.5 6.9e-08 32.2 0.5 1.3 1 0 0 1 1 1 1 Elongation complex protein 6 Elong_Iki1 PF10483.9 EPE24472.1 - 3.7e-05 23.4 1.8 4.3e-05 23.2 1.8 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 DnaB_C PF03796.15 EPE24472.1 - 0.017 14.4 0.1 0.025 13.9 0.1 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Ribosomal_L37e PF01907.19 EPE24473.1 - 1.3e-13 50.9 1.8 3.1e-13 49.7 1.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L37e BLOC1_2 PF10046.9 EPE24475.1 - 0.0004 20.6 2.6 0.0004 20.6 2.6 3.0 4 0 0 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Kre28 PF17097.5 EPE24475.1 - 0.0012 17.8 6.5 0.0016 17.5 6.5 1.1 1 0 0 1 1 1 1 Spindle pole body component Spc7 PF08317.11 EPE24475.1 - 0.0045 15.9 14.5 0.016 14.1 4.5 2.3 2 0 0 2 2 2 2 Spc7 kinetochore protein HSBP1 PF06825.12 EPE24475.1 - 0.023 14.6 0.2 0.09 12.6 0.2 2.1 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Exonuc_VII_L PF02601.15 EPE24475.1 - 0.04 13.5 5.4 0.068 12.7 5.4 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Prefoldin PF02996.17 EPE24475.1 - 0.11 12.4 16.1 0.026 14.4 2.7 3.4 2 1 2 4 4 4 0 Prefoldin subunit DUF16 PF01519.16 EPE24475.1 - 0.15 12.6 6.4 0.058 13.9 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 Cob_adeno_trans PF01923.18 EPE24475.1 - 0.73 10.0 7.0 0.54 10.4 0.7 2.8 2 1 1 3 3 3 0 Cobalamin adenosyltransferase Fez1 PF06818.15 EPE24475.1 - 1.2 9.6 13.5 2 8.8 13.2 1.6 1 1 0 1 1 1 0 Fez1 GvpK PF05121.12 EPE24475.1 - 1.2 9.2 9.6 0.12 12.5 1.7 3.0 1 1 2 3 3 3 0 Gas vesicle protein K TMPIT PF07851.13 EPE24475.1 - 1.2 8.3 4.3 2.7 7.2 3.1 1.9 2 0 0 2 2 2 0 TMPIT-like protein Atg14 PF10186.9 EPE24475.1 - 1.7 7.7 13.7 58 2.6 13.7 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YlqD PF11068.8 EPE24475.1 - 1.8 8.9 15.5 2.1 8.7 0.6 2.8 3 0 0 3 3 3 0 YlqD protein IFT20 PF14931.6 EPE24475.1 - 6.6 6.9 18.2 0.13 12.4 3.5 2.9 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF3450 PF11932.8 EPE24475.1 - 6.7 5.9 14.4 8.6 5.6 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FAD_binding_4 PF01565.23 EPE24478.1 - 2.1e-16 59.9 0.0 3.5e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain rhaM PF05336.13 EPE24479.1 - 2.1e-37 127.5 0.7 2.6e-37 127.2 0.7 1.1 1 0 0 1 1 1 1 L-rhamnose mutarotase Thioredoxin PF00085.20 EPE24480.1 - 2.7e-07 30.5 0.0 3.9e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin MFS_1 PF07690.16 EPE24482.1 - 6.9e-35 120.6 35.4 1.2e-25 90.2 14.4 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE24482.1 - 4.9e-17 61.9 0.0 4.9e-17 61.9 0.0 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter FixQ PF05545.11 EPE24482.1 - 1.8 8.6 4.6 0.41 10.6 0.4 2.1 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ ADH_zinc_N PF00107.26 EPE24484.1 - 1.2e-27 96.4 0.6 2.3e-27 95.5 0.3 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE24484.1 - 2.4e-15 57.7 0.0 6.3e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 EPE24484.1 - 0.0001 22.1 0.2 0.00016 21.5 0.2 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N PF08240.12 EPE24484.1 - 0.00039 20.3 0.0 0.0014 18.5 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sacchrp_dh_NADP PF03435.18 EPE24484.1 - 0.013 15.8 0.8 0.26 11.5 0.1 2.4 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 EPE24484.1 - 0.03 13.6 1.2 0.039 13.2 0.3 1.6 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EPE24484.1 - 0.033 13.5 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAGK_cat PF00781.24 EPE24484.1 - 0.036 13.7 0.7 0.35 10.5 0.3 2.4 2 1 0 2 2 2 0 Diacylglycerol kinase catalytic domain CMAS PF02353.20 EPE24484.1 - 0.067 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Amidohydro_1 PF01979.20 EPE24485.1 - 3.4e-78 263.4 0.0 4.1e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPE24485.1 - 3.8e-09 36.5 0.2 2.3e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family cNMP_binding PF00027.29 EPE24486.1 - 6.6e-31 106.2 1.0 1e-18 67.2 0.0 5.7 6 0 0 6 6 6 3 Cyclic nucleotide-binding domain Patatin PF01734.22 EPE24486.1 - 3.4e-16 60.0 8.4 1.5e-15 57.9 5.9 3.0 2 1 0 2 2 2 1 Patatin-like phospholipase TrbL PF04610.14 EPE24486.1 - 0.97 9.1 9.0 2.1 8.1 9.0 1.5 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein EIF_2_alpha PF07541.12 EPE24487.1 - 1.3e-36 125.2 0.0 2.5e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EPE24487.1 - 1.1e-13 51.2 0.7 2.7e-13 50.1 0.7 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Peptidase_S26 PF10502.9 EPE24488.1 - 0.00034 20.4 0.0 0.029 14.1 0.0 2.5 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 EPE24488.1 - 0.0022 17.9 0.0 0.0099 15.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase S24-like Mito_carr PF00153.27 EPE24489.1 - 6.8e-62 205.4 3.1 7.8e-21 73.8 0.5 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein PPR_2 PF13041.6 EPE24490.1 - 0.00089 19.4 0.1 3.1 8.0 0.0 4.2 4 0 0 4 4 4 2 PPR repeat family NCA2 PF08637.10 EPE24491.1 - 2.3e-112 374.9 0.0 5.1e-112 373.8 0.0 1.6 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Ras PF00071.22 EPE24492.1 - 1e-65 220.3 0.1 1.3e-65 219.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE24492.1 - 6.2e-34 116.8 0.2 1.1e-33 116.0 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE24492.1 - 4.5e-13 49.0 0.1 5.6e-13 48.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EPE24492.1 - 6.1e-06 25.9 0.1 1.3e-05 24.8 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EPE24492.1 - 0.00025 20.5 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EPE24492.1 - 0.0026 17.8 0.0 0.0079 16.3 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPE24492.1 - 0.0067 16.3 0.2 2.7 7.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EPE24492.1 - 0.083 12.4 0.0 0.46 10.0 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.6 EPE24492.1 - 0.12 12.7 0.1 0.73 10.1 0.0 2.0 1 1 0 2 2 2 0 AAA domain AAA PF00004.29 EPE24494.1 - 3.9e-54 182.6 0.0 2e-37 128.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPE24494.1 - 1.8e-10 40.4 0.3 3.5e-08 33.1 0.1 3.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EPE24494.1 - 1.1e-08 35.7 2.6 0.03 14.7 0.1 4.5 2 2 2 4 4 4 3 AAA ATPase domain AAA_5 PF07728.14 EPE24494.1 - 2.2e-05 24.5 0.2 0.024 14.7 0.0 3.6 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EPE24494.1 - 3.1e-05 23.8 0.0 0.013 15.3 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EPE24494.1 - 0.00017 21.9 0.0 0.46 10.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 EPE24494.1 - 0.0032 17.0 0.1 1.6 8.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 EPE24494.1 - 0.0035 17.5 0.0 3.3 7.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_2 PF07724.14 EPE24494.1 - 0.0037 17.4 0.1 0.066 13.3 0.0 2.9 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 EPE24494.1 - 0.0044 17.3 0.0 0.25 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EPE24494.1 - 0.0052 16.5 0.0 3.9 7.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_22 PF13401.6 EPE24494.1 - 0.0065 16.7 3.6 15 5.8 0.0 4.3 2 2 0 4 4 4 0 AAA domain AAA_25 PF13481.6 EPE24494.1 - 0.0075 15.9 6.8 5.2 6.6 0.0 4.3 3 1 1 4 4 4 1 AAA domain Mg_chelatase PF01078.21 EPE24494.1 - 0.0085 15.5 0.2 0.23 10.8 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EPE24494.1 - 0.014 15.4 0.0 6.5 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EPE24494.1 - 0.015 15.3 0.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 EPE24494.1 - 0.019 14.2 0.0 0.087 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Rad17 PF03215.15 EPE24494.1 - 0.025 14.5 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 EPE24494.1 - 0.037 14.4 0.3 0.37 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EPE24494.1 - 0.04 14.1 0.0 4.4 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EPE24494.1 - 0.04 13.6 0.1 5.4 6.7 0.0 3.4 3 1 0 3 3 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 EPE24494.1 - 0.083 11.8 0.1 0.19 10.6 0.0 1.6 2 0 0 2 2 2 0 AFG1-like ATPase ATPase PF06745.13 EPE24494.1 - 0.17 11.2 0.3 5.2 6.3 0.1 2.4 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 EPE24494.1 - 0.42 10.5 3.1 2.5 8.0 0.2 2.9 2 1 0 3 3 3 0 NACHT domain Glycos_transf_2 PF00535.26 EPE24495.1 - 9.7e-24 84.1 0.0 1.4e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EPE24495.1 - 2.1e-06 27.8 0.0 0.00031 20.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EPE24495.1 - 0.00061 19.4 0.0 0.0024 17.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 SMK-1 PF04802.15 EPE24496.1 - 1.3e-79 266.5 0.3 3.1e-79 265.3 0.3 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Adaptin_N PF01602.20 EPE24496.1 - 0.11 11.0 1.3 0.17 10.4 0.2 1.8 2 0 0 2 2 2 0 Adaptin N terminal region TMEMspv1-c74-12 PF11044.8 EPE24497.1 - 2.6 8.1 4.3 5.8 7.0 4.3 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein SE PF08491.10 EPE24498.1 - 7.6e-98 326.9 0.0 1.1e-97 326.5 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EPE24498.1 - 1.1e-08 34.8 0.5 2.4e-05 23.7 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 EPE24498.1 - 1.1e-08 35.0 0.1 1.1e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE24498.1 - 1.9e-05 24.8 0.4 4e-05 23.8 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EPE24498.1 - 2.2e-05 23.7 0.2 0.00056 19.1 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EPE24498.1 - 5.1e-05 22.5 0.7 7.7e-05 22.0 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EPE24498.1 - 0.0002 20.9 0.1 0.00029 20.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EPE24498.1 - 0.001 18.4 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EPE24498.1 - 0.002 17.4 0.1 0.0034 16.7 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE24498.1 - 0.0053 15.9 0.5 0.0091 15.1 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein ApbA PF02558.16 EPE24498.1 - 0.012 15.2 0.1 0.024 14.3 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EPE24498.1 - 0.016 15.8 0.3 0.034 14.7 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 EPE24498.1 - 0.019 14.9 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.14 EPE24498.1 - 0.02 13.6 0.3 0.032 12.9 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 EPE24498.1 - 0.041 13.8 0.1 0.067 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 EPE24498.1 - 0.086 11.7 0.2 0.23 10.3 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase ThiF PF00899.21 EPE24498.1 - 0.13 11.6 0.1 0.26 10.6 0.1 1.4 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 EPE24498.1 - 0.23 11.5 0.0 0.46 10.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pterin_4a PF01329.19 EPE24499.1 - 1.6e-25 89.0 0.0 2.1e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase FA_hydroxylase PF04116.13 EPE24500.1 - 1.3e-27 96.7 17.8 1.3e-27 96.7 17.8 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Zn_clus PF00172.18 EPE24501.1 - 0.0076 16.4 3.1 0.0076 16.4 3.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE24501.1 - 0.023 13.5 0.1 0.033 13.0 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF4079 PF13301.6 EPE24502.1 - 0.58 10.3 0.0 0.58 10.3 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) 7tm_1 PF00001.21 EPE24502.1 - 1.3 8.3 9.5 0.38 10.0 1.7 2.4 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) adh_short PF00106.25 EPE24504.1 - 1.3e-40 139.0 0.1 1.8e-40 138.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE24504.1 - 3.8e-29 101.9 0.0 5.9e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE24504.1 - 1.6e-07 31.4 1.5 1.5e-06 28.3 1.5 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE24504.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HAD_2 PF13419.6 EPE24506.1 - 6.2e-05 23.1 0.0 9.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPE24506.1 - 0.0014 18.9 0.0 0.0048 17.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TfoX_C PF04994.13 EPE24506.1 - 0.21 11.7 0.0 1.8 8.7 0.0 2.2 2 0 0 2 2 2 0 TfoX C-terminal domain SH3_9 PF14604.6 EPE24507.1 - 1.2e-11 44.3 0.3 8e-08 32.0 0.1 2.9 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 EPE24507.1 - 1.5e-06 27.8 0.5 0.00038 20.1 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EPE24507.1 - 0.04 13.5 2.0 0.099 12.3 1.0 2.1 2 0 0 2 2 2 0 SH3 domain zf-met PF12874.7 EPE24508.1 - 0.00094 19.5 0.3 0.24 11.9 0.4 3.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EPE24508.1 - 0.0073 17.1 29.0 1.3 10.1 0.3 7.1 6 1 0 6 6 6 4 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 EPE24508.1 - 0.42 10.3 4.3 0.2 11.3 0.6 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 EPE24508.1 - 1.6 9.3 36.0 5.6 7.6 0.3 7.3 7 0 0 7 7 7 0 Zinc finger, C2H2 type NAD_binding_10 PF13460.6 EPE24510.1 - 5.8e-29 101.3 0.0 7.5e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPE24510.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 EPE24510.1 - 0.021 14.3 0.2 0.062 12.8 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 EPE24511.1 - 8.6e-07 29.0 7.9 8.6e-07 29.0 7.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N PF02798.20 EPE24512.1 - 8.2e-17 61.3 0.0 1.3e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPE24512.1 - 1.2e-14 54.5 0.0 1.9e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPE24512.1 - 1e-10 41.7 0.0 1.7e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EPE24512.1 - 2.2e-10 40.6 0.0 3.7e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPE24512.1 - 4.5e-07 29.8 0.1 7.6e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPE24512.1 - 0.00051 20.2 0.0 0.00085 19.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PT PF04886.12 EPE24513.1 - 0.018 14.5 6.2 0.018 14.5 6.2 5.5 4 1 1 5 5 5 0 PT repeat Sulfate_transp PF00916.20 EPE24514.1 - 4.9e-79 265.8 13.8 6.5e-79 265.4 13.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EPE24514.1 - 4.2e-14 52.2 0.0 7.8e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EPE24514.1 - 0.016 15.6 3.9 0.016 15.6 3.9 2.8 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Glyco_hydro_61 PF03443.14 EPE24515.1 - 6.1e-60 202.7 0.5 7.1e-60 202.5 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Sugar_tr PF00083.24 EPE24516.1 - 4.1e-121 405.0 26.2 4.7e-121 404.8 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE24516.1 - 2e-22 79.6 44.4 1e-18 67.4 37.8 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EPE24516.1 - 0.00042 18.9 3.0 0.00042 18.9 3.0 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EPE24516.1 - 0.0015 17.4 11.8 0.2 10.5 2.6 3.3 2 2 1 3 3 3 3 MFS_1 like family Ytca PF17090.5 EPE24516.1 - 0.099 13.2 5.2 8.7 6.9 0.1 3.8 3 0 0 3 3 3 0 Uncharacterised protein family GATA PF00320.27 EPE24518.1 - 4.6e-29 99.7 15.8 2.1e-15 56.0 2.9 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 EPE24518.1 - 1.6e-06 27.5 1.6 0.011 15.2 0.0 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 EPE24518.1 - 0.00011 22.2 1.3 0.21 11.7 0.1 2.8 2 0 0 2 2 2 2 Zinc ribbon domain ArfGap PF01412.18 EPE24518.1 - 0.001 19.1 3.5 0.21 11.7 0.2 2.6 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf HypA PF01155.19 EPE24518.1 - 0.0082 16.2 1.8 0.9 9.6 0.1 2.4 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EPE24518.1 - 0.017 15.1 12.0 1 9.4 0.2 3.2 2 1 1 3 3 3 0 Double zinc ribbon Auto_anti-p27 PF06677.12 EPE24518.1 - 0.044 13.9 8.2 0.3 11.3 0.5 2.6 3 0 0 3 3 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) MDFI PF15316.6 EPE24518.1 - 0.047 13.8 7.3 0.63 10.1 1.1 2.8 2 0 0 2 2 2 0 MyoD family inhibitor eIF-5_eIF-2B PF01873.17 EPE24518.1 - 0.091 12.6 4.9 2.4 8.0 0.5 2.6 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-CHY PF05495.12 EPE24518.1 - 0.5 10.9 3.9 4.6 7.8 0.4 2.5 2 0 0 2 2 2 0 CHY zinc finger zinc_ribbon_2 PF13240.6 EPE24518.1 - 0.53 10.1 9.0 13 5.6 0.1 4.2 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 EPE24518.1 - 0.64 9.5 9.7 21 4.7 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon domain Ribosomal_L32p PF01783.23 EPE24518.1 - 0.96 9.8 10.4 3.2 8.1 2.0 4.2 2 2 0 2 2 2 0 Ribosomal L32p protein family HIPIP PF01355.17 EPE24518.1 - 1.5 9.2 6.4 7.1 7.1 0.2 3.8 3 1 1 4 4 4 0 High potential iron-sulfur protein ADK_lid PF05191.14 EPE24518.1 - 2.2 8.3 7.2 3.2 7.8 0.2 3.9 4 0 0 4 4 4 0 Adenylate kinase, active site lid zf-piccolo PF05715.13 EPE24518.1 - 9 6.5 8.9 1.8e+02 2.4 0.0 4.0 3 1 1 4 4 4 0 Piccolo Zn-finger CorA PF01544.18 EPE24519.1 - 0.00074 18.9 0.6 0.0011 18.3 0.6 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein OSCP PF00213.18 EPE24519.1 - 0.017 15.3 2.0 0.033 14.3 1.2 1.8 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit Mannosyl_trans4 PF15971.5 EPE24519.1 - 0.081 12.8 0.1 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 DolP-mannose mannosyltransferase DUF772 PF05598.11 EPE24519.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Transposase domain (DUF772) ISG65-75 PF11727.8 EPE24520.1 - 0.31 10.2 3.0 0.47 9.6 3.0 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein RNase_P_p30 PF01876.16 EPE24521.1 - 3e-56 190.3 0.0 3.7e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 TFIIS_M PF07500.14 EPE24522.1 - 2e-26 92.6 1.3 2.3e-26 92.5 0.2 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EPE24522.1 - 7.5e-18 64.1 6.1 1.2e-17 63.4 6.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EPE24522.1 - 1.5e-08 34.6 1.0 3.4e-08 33.4 1.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain betaPIX_CC PF16523.5 EPE24522.1 - 0.039 13.8 0.1 0.89 9.4 0.1 2.6 2 0 0 2 2 2 0 betaPIX coiled coil zf-ZPR1 PF03367.13 EPE24522.1 - 4.9 7.0 6.5 0.49 10.2 0.6 2.4 3 0 0 3 3 3 0 ZPR1 zinc-finger domain PALP PF00291.25 EPE24523.1 - 2.7e-61 207.6 0.8 3.4e-61 207.2 0.8 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Alph_Pro_TM PF09608.10 EPE24523.1 - 0.038 13.8 0.2 0.093 12.5 0.1 1.7 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) Methyltransf_28 PF02636.17 EPE24524.1 - 2.5e-42 145.3 0.0 3.7e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 EPE24524.1 - 0.0022 17.9 0.0 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase HMG-CoA_red PF00368.18 EPE24525.1 - 4.3e-143 476.8 4.3 5.7e-143 476.4 4.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 EPE24525.1 - 6.9e-50 168.9 0.1 1.2e-49 168.2 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 EPE24525.1 - 4.4e-13 49.3 6.6 1e-11 44.9 6.6 2.4 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EPE24525.1 - 9e-08 30.7 2.6 9e-08 30.7 2.6 1.5 2 0 0 2 2 2 1 Patched family Tetraspanin PF00335.20 EPE24525.1 - 0.11 12.2 2.7 0.3 10.8 2.7 1.7 1 0 0 1 1 1 0 Tetraspanin family Isochorismatase PF00857.20 EPE24526.1 - 1.4e-24 87.2 0.0 3.6e-24 85.9 0.0 1.6 1 1 0 1 1 1 1 Isochorismatase family SH3_1 PF00018.28 EPE24527.1 - 1.1e-08 34.5 0.0 2.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPE24527.1 - 4.4e-07 29.7 0.1 8.8e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EPE24527.1 - 9.1e-05 22.1 0.0 0.00021 20.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain FoP_duplication PF13865.6 EPE24527.1 - 3.3 8.3 9.4 0.24 12.0 3.4 2.2 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Ssu72 PF04722.13 EPE24528.1 - 3.9e-85 284.3 0.0 4.4e-85 284.1 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein GIT_SHD PF08518.11 EPE24529.1 - 9.6e-25 85.9 5.6 3.2e-12 45.9 2.0 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT OmpH PF03938.14 EPE24529.1 - 7.6e-05 23.1 35.4 0.051 13.9 0.2 4.7 3 1 2 5 5 5 3 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 EPE24529.1 - 0.022 14.1 28.7 0.035 13.5 23.9 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EPE24529.1 - 0.029 14.5 31.9 0.014 15.5 12.4 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus THP2 PF09432.10 EPE24529.1 - 0.092 12.8 10.3 0.022 14.8 4.0 2.7 1 1 1 2 2 2 0 Tho complex subunit THP2 GIT1_C PF12205.8 EPE24529.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.5 3 1 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term FUSC PF04632.12 EPE24529.1 - 0.15 10.6 10.9 0.46 9.0 10.9 1.9 1 0 0 1 1 1 0 Fusaric acid resistance protein family PSII_Pbs27 PF13326.6 EPE24529.1 - 0.28 11.5 5.7 2.3 8.5 0.8 2.8 2 0 0 2 2 2 0 Photosystem II Pbs27 Fez1 PF06818.15 EPE24529.1 - 0.3 11.5 30.7 1.3 9.5 11.0 2.5 1 1 1 2 2 2 0 Fez1 Lebercilin PF15619.6 EPE24529.1 - 0.41 10.3 32.2 0.056 13.1 10.8 2.9 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3573 PF12097.8 EPE24529.1 - 2.2 7.0 4.6 4.1 6.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Acetyltransf_1 PF00583.25 EPE24530.1 - 2.2e-09 37.6 0.0 2.7e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE24530.1 - 9.9e-09 35.2 0.0 1.5e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE24530.1 - 1.1e-05 25.3 0.0 2.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EPE24530.1 - 2.6e-05 24.6 0.0 3.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EPE24530.1 - 3e-05 24.7 0.0 3.9e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EPE24530.1 - 0.003 17.7 0.0 0.012 15.8 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPE24530.1 - 0.042 14.0 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3662 PF12401.8 EPE24530.1 - 0.081 13.3 0.0 0.91 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2662) FMN_bind_2 PF04299.12 EPE24531.1 - 2.4e-53 180.3 0.0 3e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain DUF3854 PF12965.7 EPE24531.1 - 0.0037 17.2 0.0 0.0088 16.0 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3854) Transp_cyt_pur PF02133.15 EPE24532.1 - 1.7e-44 152.3 35.6 2.1e-44 152.0 35.6 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Lactamase_B PF00753.27 EPE24533.1 - 9.4e-13 48.6 0.5 2.5e-12 47.2 0.5 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EPE24533.1 - 0.00057 19.5 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain LPMO_10 PF03067.15 EPE24534.1 - 0.1 13.2 0.1 0.27 11.9 0.0 1.7 2 0 0 2 2 2 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading HET PF06985.11 EPE24535.1 - 7.1e-23 81.6 0.0 1.7e-22 80.3 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF668 PF05003.12 EPE24535.1 - 0.11 13.0 0.2 0.45 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF668) Pro_isomerase PF00160.21 EPE24536.1 - 1.6e-48 165.0 0.2 1.7e-48 164.8 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-RING_2 PF13639.6 EPE24537.1 - 5.5e-12 45.8 6.1 8.7e-12 45.2 6.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPE24537.1 - 3.2e-08 33.3 5.6 5e-08 32.6 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EPE24537.1 - 4.6e-08 32.7 0.8 7.8e-08 31.9 0.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EPE24537.1 - 7.2e-08 32.2 3.5 1.2e-07 31.5 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPE24537.1 - 3.1e-06 27.4 8.4 1.4e-05 25.3 8.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EPE24537.1 - 4.5e-06 26.5 3.2 7e-06 25.9 3.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EPE24537.1 - 0.00044 20.2 0.9 0.00044 20.2 0.9 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EPE24537.1 - 0.0022 17.8 2.0 0.0037 17.1 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EPE24537.1 - 0.003 17.6 2.8 0.0081 16.2 2.8 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EPE24537.1 - 0.016 15.0 6.2 0.03 14.1 6.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EPE24537.1 - 0.057 13.3 4.4 0.12 12.3 4.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EPE24537.1 - 0.087 13.0 3.0 0.24 11.6 3.0 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EPE24537.1 - 0.11 12.1 3.3 0.2 11.3 3.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 EPE24537.1 - 0.17 11.8 5.2 0.29 11.0 5.2 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 EPE24537.1 - 0.41 10.9 4.1 0.84 9.9 4.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING OAD_gamma PF04277.13 EPE24537.1 - 0.78 10.4 0.0 0.78 10.4 0.0 3.2 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain RINGv PF12906.7 EPE24537.1 - 1 9.5 5.3 2.1 8.5 5.3 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 EPE24537.1 - 6.2 6.8 8.7 0.15 12.0 1.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3752 PF12572.8 EPE24538.1 - 4.5e-42 144.1 10.9 7.1e-42 143.5 10.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Vps8 PF12816.7 EPE24539.1 - 2e-72 242.9 0.1 4.1e-72 241.9 0.1 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EPE24539.1 - 0.00022 21.1 0.0 0.68 9.8 0.0 2.9 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 EPE24539.1 - 0.0072 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EPE24539.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 EPE24539.1 - 0.07 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EPE24539.1 - 0.071 12.9 1.1 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_2 PF13639.6 EPE24539.1 - 0.34 11.3 1.0 0.59 10.5 0.0 1.9 2 0 0 2 2 2 0 Ring finger domain zf-C3H2C3 PF17122.5 EPE24539.1 - 2.8 8.1 4.2 0.62 10.1 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger RTA1 PF04479.13 EPE24542.1 - 4e-61 206.2 4.5 5.6e-61 205.8 4.5 1.2 1 0 0 1 1 1 1 RTA1 like protein ADH_zinc_N PF00107.26 EPE24543.1 - 1.3e-07 31.6 0.6 2.6e-07 30.7 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE24543.1 - 3.8e-06 26.8 0.0 6.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 EPE24543.1 - 0.0022 17.5 0.2 0.0038 16.7 0.2 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_N_2 PF16884.5 EPE24543.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase SspN PF08177.11 EPE24543.1 - 0.02 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Small acid-soluble spore protein N family ADH_zinc_N_2 PF13602.6 EPE24543.1 - 0.045 14.8 0.0 0.081 14.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF2374 PF09574.10 EPE24543.1 - 0.12 12.2 0.9 0.25 11.2 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) F-box PF00646.33 EPE24544.1 - 0.067 13.1 0.3 0.17 11.8 0.3 1.7 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 EPE24544.1 - 0.09 12.7 0.1 0.09 12.7 0.1 2.2 2 0 0 2 2 2 0 F-box DUF1075 PF06388.11 EPE24545.1 - 0.092 12.8 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) ADH_zinc_N PF00107.26 EPE24546.1 - 2.5e-22 79.2 0.1 3.9e-22 78.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EPE24546.1 - 6.8e-19 67.8 0.0 1.4e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EPE24546.1 - 8.5e-09 36.6 0.0 1.5e-08 35.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RRM_1 PF00076.22 EPE24548.1 - 3.5e-05 23.6 0.0 0.014 15.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EPE24548.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Peptidase_S8 PF00082.22 EPE24550.1 - 4.7e-37 127.9 0.6 6.6e-37 127.4 0.6 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EPE24550.1 - 1.2e-24 86.1 0.5 2.5e-24 85.1 0.5 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 EPE24550.1 - 0.092 13.5 0.1 0.27 12.0 0.1 1.8 1 0 0 1 1 1 0 Peptidase S8 pro-domain Glyco_hydro_3_C PF01915.22 EPE24551.1 - 3.7e-67 226.2 0.0 1.7e-66 224.0 0.0 2.1 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE24551.1 - 2.6e-52 178.2 0.0 4.9e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE24551.1 - 5.3e-22 77.7 0.0 1.1e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EPE24551.1 - 3e-15 56.3 0.5 1.8e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 PA14 domain DUF202 PF02656.15 EPE24553.1 - 4.2e-17 62.3 4.4 4.7e-17 62.2 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Baculo_11_kDa PF06143.11 EPE24553.1 - 0.18 11.4 0.8 0.3 10.7 0.8 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Cation_efflux PF01545.21 EPE24554.1 - 4.6e-46 157.1 16.3 2.2e-45 154.9 16.3 1.8 1 1 0 1 1 1 1 Cation efflux family Squash PF00299.18 EPE24554.1 - 7.8 6.6 13.5 15 5.7 13.5 1.4 1 0 0 1 1 1 0 Squash family serine protease inhibitor Myosin_head PF00063.21 EPE24555.1 - 3.6e-235 782.3 2.0 4.4e-235 782.0 2.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EPE24555.1 - 1.5e-49 168.2 0.0 2.8e-49 167.4 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EPE24555.1 - 5.6e-11 41.9 0.1 1.1e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPE24555.1 - 3.3e-07 30.1 0.1 8.8e-07 28.7 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EPE24555.1 - 9.6e-07 28.4 0.0 2.2e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Hpr_kinase_C PF07475.12 EPE24555.1 - 0.0087 15.6 0.3 3.2 7.2 0.1 2.4 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 EPE24555.1 - 0.022 15.0 0.0 0.061 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EPE24555.1 - 0.059 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain IQ PF00612.27 EPE24555.1 - 0.062 13.1 9.8 1.9 8.5 1.2 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif RNA_helicase PF00910.22 EPE24555.1 - 0.072 13.5 0.3 0.56 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Sigma54_activat PF00158.26 EPE24555.1 - 0.15 11.7 0.4 0.93 9.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain SET PF00856.28 EPE24556.1 - 6.9e-14 52.6 0.1 1.9e-13 51.1 0.1 1.7 1 1 0 1 1 1 1 SET domain FAD_binding_8 PF08022.12 EPE24558.1 - 3.6e-22 78.5 0.0 7.5e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EPE24558.1 - 4.1e-22 79.0 0.0 6.8e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EPE24558.1 - 6.9e-19 68.2 8.0 6.9e-19 68.2 8.0 2.0 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 EPE24558.1 - 0.013 15.8 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain ubiquitin PF00240.23 EPE24559.1 - 1.1e-16 60.3 0.0 1.6e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EPE24559.1 - 6e-05 22.8 0.1 6e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 UBA/TS-N domain STI1 PF17830.1 EPE24559.1 - 0.00071 19.5 15.4 0.06 13.3 1.4 2.9 2 0 0 2 2 2 2 STI1 domain Rad60-SLD_2 PF13881.6 EPE24559.1 - 0.0011 19.1 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 EPE24559.1 - 0.028 14.2 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 EPE24559.1 - 0.035 14.1 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair DUF2407 PF10302.9 EPE24559.1 - 0.079 13.5 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain RPN13_C PF16550.5 EPE24559.1 - 0.082 13.1 0.2 0.22 11.7 0.2 1.7 1 0 0 1 1 1 0 UCH-binding domain GerD PF17898.1 EPE24559.1 - 0.18 11.8 5.6 0.58 10.1 4.9 1.9 1 1 0 1 1 1 0 Spore germination GerD central core domain ADH_zinc_N PF00107.26 EPE24560.1 - 1.4e-32 112.4 0.1 2.7e-32 111.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE24560.1 - 2.2e-11 44.9 0.0 3.8e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE24560.1 - 4.4e-06 26.5 0.0 3e-05 23.8 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EPE24560.1 - 0.0013 18.1 1.7 0.0024 17.2 1.1 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EPE24560.1 - 0.013 15.8 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain SprT-like PF10263.9 EPE24562.1 - 2.9e-13 49.7 0.0 4.7e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 SprT-like family F-box-like PF12937.7 EPE24564.1 - 6.9e-08 32.3 0.7 1.3e-07 31.3 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE24564.1 - 8.1e-05 22.4 0.2 0.00017 21.3 0.2 1.6 1 0 0 1 1 1 1 F-box domain DUF1713 PF08213.11 EPE24566.1 - 1.1e-11 44.4 20.0 1.1e-11 44.4 20.0 1.8 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 EPE24566.1 - 7.1e-05 23.5 0.1 7.1e-05 23.5 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial protein Pet20 Asp PF00026.23 EPE24567.1 - 1.1e-43 149.9 0.1 2.3e-26 93.0 0.3 2.0 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPE24567.1 - 3.2e-07 30.8 0.4 2.4e-06 27.9 0.4 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EPE24567.1 - 1.8e-06 28.5 0.3 0.27 11.9 0.0 3.4 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EPE24567.1 - 2.3e-05 24.8 0.1 0.011 16.3 0.0 3.4 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease DsbC_N PF10411.9 EPE24567.1 - 0.12 11.9 0.1 0.35 10.4 0.1 1.7 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus UDPGP PF01704.18 EPE24570.1 - 1e-55 189.1 0.0 1.4e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Fer4_20 PF14691.6 EPE24570.1 - 0.04 13.7 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NTP_transf_3 PF12804.7 EPE24570.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain UQ_con PF00179.26 EPE24571.1 - 6.1e-49 165.3 0.0 7.7e-49 165.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPE24571.1 - 2.7e-06 27.1 0.0 3.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EPE24571.1 - 0.00059 20.1 0.1 0.0012 19.1 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 EPE24571.1 - 0.018 14.9 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain Pkinase PF00069.25 EPE24572.1 - 6.2e-59 199.5 0.0 8e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE24572.1 - 2.4e-28 99.1 0.0 3.5e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE24572.1 - 3.1e-09 36.6 0.0 4.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPE24572.1 - 0.0013 18.7 0.0 1.3 8.9 0.0 2.6 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EPE24572.1 - 0.025 14.0 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UDG PF03167.19 EPE24573.1 - 7.3e-16 58.5 0.0 1.2e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Ribosomal_L31e PF01198.19 EPE24574.1 - 6.7e-41 138.4 0.4 9.2e-41 138.0 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e TrbC_Ftype PF09673.10 EPE24574.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein RGS PF00615.19 EPE24575.1 - 2e-12 47.4 0.0 4.1e-09 36.7 0.0 2.5 2 1 0 2 2 2 2 Regulator of G protein signaling domain FA_desaturase PF00487.24 EPE24575.1 - 7.6 6.3 8.5 4.1 7.2 5.1 1.9 1 1 1 2 2 2 0 Fatty acid desaturase PCI PF01399.27 EPE24576.1 - 7.8e-05 23.1 0.0 0.00014 22.3 0.0 1.5 1 1 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 EPE24576.1 - 0.0019 18.1 0.2 0.0029 17.5 0.2 1.3 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain DivIC PF04977.15 EPE24576.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator HMA PF00403.26 EPE24577.1 - 3.5e-52 174.7 0.8 3e-13 50.0 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 EPE24577.1 - 5e-50 169.5 0.7 5e-50 169.5 0.7 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EPE24577.1 - 1.3e-41 143.2 1.3 1.3e-41 143.2 1.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EPE24577.1 - 7.5e-07 29.1 0.7 7.5e-05 22.6 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase zinc_ribbon_12 PF11331.8 EPE24577.1 - 0.011 15.5 0.3 15 5.5 0.0 3.4 3 0 0 3 3 3 0 Probable zinc-ribbon domain FAM70 PF14967.6 EPE24577.1 - 0.012 15.1 0.1 7 6.0 0.0 2.7 2 0 0 2 2 2 0 FAM70 protein HAD PF12710.7 EPE24577.1 - 0.063 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EPE24577.1 - 0.19 11.8 0.1 0.64 10.1 0.1 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2089 PF09862.9 EPE24577.1 - 0.23 11.5 1.1 32 4.6 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2089) DUF1656 PF07869.12 EPE24577.1 - 7.7 6.6 8.4 22 5.2 3.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) DUF155 PF02582.14 EPE24578.1 - 3.6e-57 193.3 0.1 6.2e-57 192.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 bZIP_2 PF07716.15 EPE24578.1 - 1.3 9.2 7.0 2.4 8.3 7.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper p450 PF00067.22 EPE24579.1 - 6.8e-63 213.0 0.0 1.3e-62 212.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 cNMPbd_u2 PF16643.5 EPE24581.1 - 1.1e-39 136.4 21.6 2.1e-39 135.5 21.6 1.5 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 EPE24581.1 - 1.9e-34 117.6 0.0 3.6e-18 65.4 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 EPE24581.1 - 9.9e-10 37.7 7.5 3.8 7.8 0.0 8.1 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 EPE24581.1 - 5.4e-06 26.6 3.7 1.4 9.5 0.1 5.9 3 3 2 5 5 5 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EPE24581.1 - 3.9e-05 23.4 0.3 3.9e-05 23.4 0.3 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EPE24581.1 - 0.00089 19.1 5.9 0.00097 19.0 0.7 3.5 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 EPE24581.1 - 0.19 12.4 16.2 42 5.2 0.5 8.0 9 2 0 9 9 9 0 Leucine Rich Repeat Dynamitin PF04912.14 EPE24582.1 - 0.046 13.1 0.5 0.068 12.5 0.5 1.2 1 0 0 1 1 1 0 Dynamitin Utp12 PF04003.12 EPE24582.1 - 0.095 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family Cactin_mid PF10312.9 EPE24583.1 - 5.1e-65 218.9 3.1 5.1e-65 218.9 3.1 1.6 2 0 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.9 EPE24583.1 - 6.2e-52 174.8 3.8 4.1e-51 172.1 1.9 2.3 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 EPE24583.1 - 0.019 15.4 0.0 0.083 13.3 0.0 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) YolD PF08863.10 EPE24583.1 - 0.1 12.7 0.2 0.4 10.7 0.2 2.0 1 0 0 1 1 1 0 YolD-like protein DUF1087 PF06465.13 EPE24583.1 - 0.14 12.2 2.3 0.42 10.7 0.3 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF1139 PF06599.11 EPE24583.1 - 0.34 10.2 2.6 0.18 11.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1139) Forkhead PF00250.18 EPE24584.1 - 2.2e-19 69.5 0.0 7.3e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 Forkhead domain Glyco_hydro_28 PF00295.17 EPE24585.1 - 1.5e-51 175.4 7.1 2.2e-51 174.8 7.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 XLF PF09302.11 EPE24586.1 - 2.5e-55 187.4 0.9 3.8e-55 186.8 0.9 1.3 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component WD40 PF00400.32 EPE24588.1 - 7.4e-09 36.1 12.2 0.00068 20.4 1.4 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE24588.1 - 7.2e-05 23.0 0.2 0.26 11.6 0.0 4.4 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE24588.1 - 0.0064 16.4 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A zf-RING_9 PF13901.6 EPE24588.1 - 2.3 8.2 6.6 6.3 6.7 6.6 1.7 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Myb_DNA-bind_6 PF13921.6 EPE24589.1 - 0.047 13.9 0.4 0.33 11.2 0.1 2.2 1 1 1 2 2 2 0 Myb-like DNA-binding domain Zn_clus PF00172.18 EPE24590.1 - 4.9e-06 26.6 9.6 4.9e-06 26.6 9.6 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE24590.1 - 0.00039 19.5 0.5 0.0012 18.0 0.5 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMPKBI PF04739.15 EPE24590.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interaction domain Cellulase PF00150.18 EPE24592.1 - 2.3e-15 56.8 2.2 2.3e-15 56.8 2.2 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Aldedh PF00171.22 EPE24593.1 - 7.8e-140 466.4 0.2 9.3e-140 466.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmdA PF13376.6 EPE24593.1 - 0.16 12.0 1.2 0.68 10.0 0.2 2.2 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated IBN_N PF03810.19 EPE24594.1 - 4.4e-11 42.5 0.0 3.8e-10 39.5 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EPE24594.1 - 0.047 13.8 2.5 0.37 10.8 0.3 3.1 2 1 1 3 3 3 0 Exportin 1-like protein Ank_2 PF12796.7 EPE24595.1 - 4.3e-16 59.3 0.1 0.00038 21.0 0.0 4.9 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE24595.1 - 9.7e-13 47.1 0.1 0.1 13.2 0.0 7.7 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.6 EPE24595.1 - 8e-12 45.4 0.0 0.0025 18.3 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EPE24595.1 - 1e-08 35.2 2.2 0.22 12.0 0.0 6.9 6 1 1 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 EPE24595.1 - 1.1e-07 32.0 0.1 0.025 14.9 0.0 4.6 3 3 3 6 6 6 2 Ankyrin repeats (many copies) PLC-beta_C PF08703.10 EPE24595.1 - 0.0054 16.7 0.2 0.0095 15.9 0.2 1.3 1 0 0 1 1 1 1 PLC-beta C terminal MFS_1 PF07690.16 EPE24596.1 - 2.2e-52 178.2 52.0 4e-52 177.3 52.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE24596.1 - 8.1e-24 84.0 21.6 1e-23 83.7 21.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPE24596.1 - 7.2e-19 68.0 6.6 7.2e-19 68.0 6.6 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter DUF3959 PF13105.6 EPE24596.1 - 0.53 9.8 4.7 1.2 8.5 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) GCS2 PF04107.13 EPE24596.1 - 1.9 7.8 3.9 14 4.9 1.5 2.2 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) MFS_1 PF07690.16 EPE24597.1 - 5.8e-47 160.3 41.7 1.8e-44 152.1 40.5 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE24597.1 - 4.5e-13 48.9 8.7 4.5e-13 48.9 8.7 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EPE24597.1 - 2.2e-08 33.0 5.6 2.2e-08 33.0 5.6 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2140 PF09911.9 EPE24597.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Zn_clus PF00172.18 EPE24598.1 - 0.002 18.2 9.2 0.0032 17.5 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM199X PF15814.5 EPE24598.1 - 0.027 13.5 2.9 0.021 13.9 1.2 1.7 2 0 0 2 2 2 0 Protein family FAM199X ADH_zinc_N_2 PF13602.6 EPE24600.1 - 8.4e-08 33.3 0.3 3.1e-07 31.5 0.3 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE24600.1 - 6e-07 29.3 0.3 1.6e-06 28.0 0.3 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE24600.1 - 4.6e-06 26.6 0.5 1.1e-05 25.4 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DapB_N PF01113.20 EPE24600.1 - 0.071 13.2 0.1 0.25 11.5 0.1 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Zn_clus PF00172.18 EPE24602.1 - 3.1e-09 36.8 5.9 5.1e-09 36.1 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE24602.1 - 0.00039 19.5 0.0 0.00065 18.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pex2_Pex12 PF04757.14 EPE24603.1 - 3.1e-37 128.3 1.1 4.7e-37 127.7 1.1 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EPE24603.1 - 0.00093 19.3 3.9 0.0018 18.4 3.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EPE24603.1 - 0.032 14.2 1.4 0.1 12.6 1.4 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EPE24603.1 - 1.1 9.2 7.6 2.6 8.0 4.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Na_H_Exchanger PF00999.21 EPE24604.1 - 1.8e-59 201.5 25.3 2.3e-59 201.1 25.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PTS_EIIC_2 PF13303.6 EPE24604.1 - 0.0076 15.3 0.7 0.0076 15.3 0.7 2.4 2 1 0 2 2 2 1 Phosphotransferase system, EIIC YIEGIA PF14045.6 EPE24604.1 - 0.17 10.7 0.4 0.26 10.1 0.4 1.3 1 0 0 1 1 1 0 YIEGIA protein DUF3481 PF11980.8 EPE24604.1 - 0.22 11.3 0.7 11 5.7 0.1 3.1 3 0 0 3 3 3 0 C-terminal domain of neuropilin glycoprotein SET PF00856.28 EPE24605.1 - 1.1e-09 39.0 1.2 3.5e-08 34.0 0.2 2.9 2 1 0 2 2 2 1 SET domain HCO3_cotransp PF00955.21 EPE24606.1 - 6.2e-66 223.3 9.4 1e-32 113.7 0.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family COX7a PF02238.15 EPE24606.1 - 1.6 9.2 5.6 8.3 6.9 0.0 3.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII PEP_mutase PF13714.6 EPE24607.1 - 2.3e-41 141.8 1.3 2.7e-41 141.6 1.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EPE24607.1 - 8.2e-20 70.8 0.4 1.1e-19 70.4 0.4 1.1 1 0 0 1 1 1 1 Isocitrate lyase family WLM PF08325.10 EPE24608.1 - 6.4e-60 202.5 0.2 1.1e-59 201.8 0.2 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 EPE24608.1 - 0.0041 16.4 3.4 0.0041 16.4 3.4 3.4 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.7 EPE24608.1 - 0.18 11.8 11.2 0.35 10.9 11.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-Sec23_Sec24 PF04810.15 EPE24608.1 - 0.28 11.3 14.1 1.2 9.3 0.2 3.5 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger DUF45 PF01863.17 EPE24608.1 - 0.38 10.8 3.5 0.31 11.1 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 C1_2 PF03107.16 EPE24608.1 - 0.45 10.9 8.3 2.3 8.6 0.8 2.5 2 0 0 2 2 2 0 C1 domain Zf_RING PF16744.5 EPE24608.1 - 2.5 8.3 13.1 0.16 12.1 5.6 2.6 1 1 1 2 2 2 0 KIAA1045 RING finger DUF1776 PF08643.10 EPE24609.1 - 2.8e-92 309.3 0.4 7e-92 307.9 0.0 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) PRIMA1 PF16101.5 EPE24609.1 - 5.1e-05 23.3 0.1 0.00011 22.3 0.1 1.4 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 adh_short PF00106.25 EPE24609.1 - 0.001 18.6 0.0 0.12 11.8 0.0 3.4 2 1 0 2 2 2 1 short chain dehydrogenase Dscam_C PF12355.8 EPE24609.1 - 0.0043 18.0 0.7 0.013 16.4 0.7 1.8 1 0 0 1 1 1 1 Down syndrome cell adhesion molecule C terminal zf-CCCH PF00642.24 EPE24610.1 - 1.2e-25 88.8 30.9 6.9e-07 29.0 0.4 5.2 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EPE24610.1 - 7.5e-21 73.5 32.6 1.2e-06 28.4 1.9 5.3 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 EPE24610.1 - 3.6e-14 53.4 22.0 0.00012 22.7 0.6 5.2 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 EPE24610.1 - 2.7e-08 33.4 32.6 9.9e-06 25.2 0.4 5.3 5 0 0 5 5 5 4 CCCH-type zinc finger DiSB-ORF2_chro PF16506.5 EPE24610.1 - 0.0055 16.7 3.0 0.31 11.1 0.2 2.5 2 0 0 2 2 2 2 Putative virion glycoprotein of insect viruses zf-CCCH_3 PF15663.5 EPE24610.1 - 0.02 15.1 1.8 0.02 15.1 1.8 3.2 1 1 2 3 3 3 0 Zinc-finger containing family zf-C3H1 PF10650.9 EPE24610.1 - 0.19 11.5 13.3 1.2 8.9 0.4 4.3 5 0 0 5 5 5 0 Putative zinc-finger domain TRP_N PF14558.6 EPE24610.1 - 2.4 8.5 5.5 13 6.2 0.1 2.5 2 1 1 3 3 3 0 ML-like domain GRP PF07172.11 EPE24610.1 - 8.2 7.2 19.0 12 6.6 19.0 1.2 1 0 0 1 1 1 0 Glycine rich protein family zf-CCCH_2 PF14608.6 EPE24610.1 - 9.6 6.8 37.9 0.71 10.4 1.8 5.2 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger Glyco_hydro_18 PF00704.28 EPE24611.1 - 1.1e-71 242.2 0.0 1.2e-71 242.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_64 PF16483.5 EPE24612.1 - 2.8e-141 471.1 0.1 3.2e-141 470.9 0.1 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase IBR PF01485.21 EPE24613.1 - 1.1e-09 38.3 39.2 6.6e-06 26.3 6.1 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EPE24613.1 - 0.014 15.2 1.9 0.014 15.2 1.9 3.5 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Acetyltransf_1 PF00583.25 EPE24614.1 - 8.3e-08 32.5 0.0 1.9e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE24614.1 - 4.6e-06 27.0 0.0 1.1e-05 25.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPE24614.1 - 0.00033 20.6 0.0 0.00056 19.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.6 EPE24615.1 - 2.1e-22 79.5 24.9 3.4e-22 78.9 24.9 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE24615.1 - 1.6e-05 23.7 21.0 2e-05 23.4 21.0 1.0 1 0 0 1 1 1 1 Amino acid permease VASt PF16016.5 EPE24616.1 - 1.4e-36 126.2 0.0 2.4e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EPE24616.1 - 4.5e-23 81.3 0.0 7.5e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 GRAM domain DUF1729 PF08354.10 EPE24617.1 - 1.8e-159 530.4 0.0 2.7e-159 529.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EPE24617.1 - 3.1e-89 299.6 0.0 3.4e-88 296.2 0.0 2.6 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 EPE24617.1 - 1.4e-50 170.9 0.0 4.7e-50 169.2 0.0 2.0 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 EPE24617.1 - 7.7e-38 128.8 0.0 1.6e-37 127.8 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain SAT PF16073.5 EPE24617.1 - 1.1e-37 130.1 0.0 2.6e-37 128.9 0.0 1.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_N PF17828.1 EPE24617.1 - 3e-37 127.5 0.0 7.6e-37 126.2 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 EPE24617.1 - 4.8e-24 85.0 0.0 1.7e-23 83.2 0.0 2.1 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase PCIF1_WW PF12237.8 EPE24617.1 - 0.19 11.3 0.0 0.54 9.9 0.0 1.6 2 0 0 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain FAS_I_H PF18314.1 EPE24618.1 - 4.3e-79 264.9 0.0 8.6e-79 263.9 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EPE24618.1 - 8.1e-76 253.9 0.0 1.6e-75 252.9 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 EPE24618.1 - 1.5e-20 73.8 0.0 2.9e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EPE24618.1 - 1.2e-18 67.3 0.1 3.6e-18 65.8 0.1 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EPE24618.1 - 1.4e-11 44.4 0.2 1.1e-10 41.5 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EPE24618.1 - 6.3e-06 25.8 0.0 1.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE24618.1 - 0.0054 16.7 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 KR domain Tannase PF07519.11 EPE24619.1 - 1.6e-111 373.6 2.7 1.9e-111 373.3 2.7 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 EPE24619.1 - 0.00089 18.6 0.0 0.0094 15.2 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE24619.1 - 0.0049 16.5 0.1 0.009 15.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold HET PF06985.11 EPE24620.1 - 1.5e-31 109.8 0.2 2.6e-31 108.9 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) pPIWI_RE_REase PF18154.1 EPE24621.1 - 0.21 11.5 0.4 0.4 10.7 0.4 1.5 1 1 0 1 1 1 0 REase associating with pPIWI_RE Actin PF00022.19 EPE24622.1 - 5.7e-18 64.7 0.0 1.8e-14 53.2 0.0 2.6 3 0 0 3 3 3 2 Actin MreB_Mbl PF06723.13 EPE24622.1 - 3.8e-08 32.5 0.0 0.00011 21.1 0.0 2.9 2 1 0 2 2 2 2 MreB/Mbl protein PilM_2 PF11104.8 EPE24622.1 - 0.00023 20.3 0.0 0.00082 18.5 0.0 1.7 2 0 0 2 2 2 1 Type IV pilus assembly protein PilM; PIN_3 PF13470.6 EPE24622.1 - 0.099 13.4 0.2 0.67 10.7 0.0 2.2 2 0 0 2 2 2 0 PIN domain Ras PF00071.22 EPE24624.1 - 6.8e-41 139.6 0.0 1.6e-38 131.9 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EPE24624.1 - 6.6e-31 107.0 0.0 8.8e-31 106.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE24624.1 - 1.8e-11 43.8 0.0 3.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPE24624.1 - 0.00045 20.3 0.0 0.00081 19.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EPE24624.1 - 0.007 16.8 0.0 0.009 16.4 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 EPE24624.1 - 0.0086 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EPE24624.1 - 0.022 14.8 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 EPE24624.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 EPE24624.1 - 0.097 12.4 0.1 0.19 11.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EPE24624.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.5 2 0 0 2 2 2 0 Dynamin family FAD_binding_2 PF00890.24 EPE24625.1 - 2.5e-84 283.8 0.8 3.2e-84 283.4 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EPE24625.1 - 5e-22 77.8 0.1 5.4e-21 74.5 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EPE24625.1 - 6.2e-15 55.6 0.3 1.1e-14 54.8 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EPE24625.1 - 2.2e-09 37.2 1.0 8.5e-09 35.3 1.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE24625.1 - 1.1e-07 31.9 2.1 1.3e-06 28.5 0.6 3.0 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE24625.1 - 9.2e-07 28.4 0.4 4.6e-06 26.1 0.2 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE24625.1 - 3.1e-06 26.7 0.1 0.02 14.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE24625.1 - 0.00018 20.8 2.5 0.041 13.1 0.4 3.1 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 EPE24625.1 - 0.00022 20.1 4.2 0.0097 14.7 0.3 3.2 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 EPE24625.1 - 0.00044 19.4 3.2 0.081 12.0 0.6 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.27 EPE24625.1 - 0.0028 18.2 2.1 2.1 9.0 0.5 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EPE24625.1 - 0.0034 16.7 1.0 0.31 10.3 0.2 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EPE24625.1 - 0.0044 16.3 4.2 0.035 13.3 4.2 2.0 1 1 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EPE24625.1 - 0.042 13.1 0.8 0.077 12.3 0.8 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sin3a_C PF16879.5 EPE24626.1 - 2.8e-69 234.0 0.7 2.8e-69 234.0 0.7 2.9 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 EPE24626.1 - 2.1e-48 162.2 2.6 1.1e-17 63.9 0.0 4.4 3 1 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EPE24626.1 - 1.5e-34 118.0 0.8 3.6e-31 107.1 0.1 3.7 3 0 0 3 3 3 2 Sin3 family co-repressor PhageMin_Tail PF10145.9 EPE24626.1 - 0.082 12.8 1.3 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Phage-related minor tail protein Arm_3 PF16186.5 EPE24626.1 - 0.33 10.6 4.0 1.4 8.5 0.4 2.9 3 0 0 3 3 3 0 Atypical Arm repeat OTT_1508_deam PF14441.6 EPE24626.1 - 0.58 10.2 3.3 1.5 8.9 3.3 1.7 1 0 0 1 1 1 0 OTT_1508-like deaminase DMRT-like PF15791.5 EPE24627.1 - 0.021 15.3 1.6 0.026 14.9 1.6 1.2 1 0 0 1 1 1 0 Doublesex-and mab-3-related transcription factor C1 and C2 MTBP_mid PF14919.6 EPE24627.1 - 0.043 13.0 2.4 0.045 12.9 2.4 1.2 1 0 0 1 1 1 0 MDM2-binding Band_3_cyto PF07565.13 EPE24627.1 - 0.2 11.5 4.2 0.24 11.1 4.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SAP PF02037.27 EPE24628.1 - 0.00012 21.8 0.1 0.00012 21.8 0.1 2.1 2 0 0 2 2 2 1 SAP domain Adenyl_transf PF04439.12 EPE24628.1 - 0.085 11.9 0.0 0.18 10.9 0.0 1.5 2 0 0 2 2 2 0 Streptomycin adenylyltransferase DUF349 PF03993.12 EPE24628.1 - 3.8 7.9 11.3 15 6.0 11.3 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) YkyA PF10368.9 EPE24629.1 - 0.013 15.2 2.3 0.021 14.5 2.3 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Peptidase_M16 PF00675.20 EPE24631.1 - 1.4e-54 184.1 0.2 5.1e-54 182.3 0.3 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EPE24631.1 - 9.4e-38 130.0 0.0 8e-37 127.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain CybS PF05328.12 EPE24632.1 - 7.3e-52 174.6 0.0 9.4e-52 174.2 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Pyr_redox_2 PF07992.14 EPE24636.1 - 7.4e-50 169.8 3.0 9.5e-50 169.5 3.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE24636.1 - 1.8e-17 63.6 1.2 3.3e-16 59.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE24636.1 - 5.6e-16 58.9 6.5 1.8e-14 54.0 1.6 3.4 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EPE24636.1 - 2.7e-05 24.5 0.8 0.0066 16.9 0.1 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 EPE24636.1 - 8.3e-05 21.9 2.0 0.00043 19.6 0.0 2.5 2 1 1 3 3 3 1 Thi4 family DAO PF01266.24 EPE24636.1 - 0.00043 20.0 0.9 1.1 8.7 0.1 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE24636.1 - 0.0007 19.8 1.6 0.057 13.7 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EPE24636.1 - 0.0024 17.3 0.2 0.056 12.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EPE24636.1 - 0.0035 16.6 2.5 3 7.0 0.0 3.1 2 1 1 3 3 3 2 FAD binding domain Shikimate_DH PF01488.20 EPE24636.1 - 0.018 15.1 0.7 13 5.9 0.2 3.0 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 EPE24636.1 - 0.021 13.9 0.6 1.3 8.1 0.1 3.2 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EPE24636.1 - 0.024 13.5 0.7 0.51 9.1 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_2 PF00890.24 EPE24636.1 - 0.025 13.6 8.5 0.39 9.8 0.7 3.1 2 1 0 3 3 3 0 FAD binding domain GIDA PF01134.22 EPE24636.1 - 0.027 13.6 7.4 0.92 8.5 0.4 3.8 3 1 1 4 4 4 0 Glucose inhibited division protein A HI0933_like PF03486.14 EPE24636.1 - 0.047 12.4 1.5 3.5 6.2 0.1 3.2 2 2 0 3 3 3 0 HI0933-like protein PX PF00787.24 EPE24637.1 - 1.9e-21 76.1 0.2 8.6e-21 74.0 0.1 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EPE24637.1 - 2e-09 37.4 5.9 0.00029 20.4 0.1 2.3 1 1 1 2 2 2 2 Vps5 C terminal like BAR PF03114.18 EPE24637.1 - 0.00037 20.2 5.2 0.0066 16.1 5.2 2.2 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EPE24637.1 - 0.016 14.9 0.4 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 BAR domain of APPL family FlaC_arch PF05377.11 EPE24637.1 - 0.078 13.4 0.8 29 5.2 0.1 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 EPE24637.1 - 0.39 9.6 4.9 0.34 9.7 0.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 EPE24637.1 - 0.93 10.0 7.3 13 6.3 5.7 2.9 3 1 0 3 3 3 0 Apg6 coiled-coil region DUF1664 PF07889.12 EPE24637.1 - 3.5 7.7 4.2 16 5.6 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Inhibitor_I36 PF03995.13 EPE24639.1 - 0.014 15.3 0.8 0.029 14.3 0.4 1.7 1 1 1 2 2 2 0 Peptidase inhibitor family I36 Sema PF01403.19 EPE24639.1 - 0.09 11.6 0.5 0.12 11.2 0.5 1.1 1 0 0 1 1 1 0 Sema domain WD40_3 PF15911.5 EPE24639.1 - 0.096 12.7 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 WD domain, G-beta repeat TPR_MLP1_2 PF07926.12 EPE24640.1 - 0.0041 17.2 47.5 0.065 13.3 15.8 4.0 2 1 0 3 3 3 2 TPR/MLP1/MLP2-like protein TrbI_Ftype PF09677.10 EPE24640.1 - 0.12 12.7 0.5 0.38 11.1 0.5 1.9 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) DUF1664 PF07889.12 EPE24640.1 - 4.4 7.4 27.4 0.3 11.1 2.1 4.3 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) MFS_1 PF07690.16 EPE24641.1 - 8.3e-33 113.8 21.9 1.1e-32 113.4 21.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ion_trans_2 PF07885.16 EPE24641.1 - 5.8 7.0 15.3 0.063 13.2 2.2 3.3 3 0 0 3 3 3 0 Ion channel GFO_IDH_MocA PF01408.22 EPE24642.1 - 4.4e-17 63.0 0.0 8.5e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EPE24642.1 - 8.8e-17 61.2 0.1 3.8e-16 59.1 0.1 2.0 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain PP_kinase_N PF13089.6 EPE24643.1 - 0.022 15.1 0.3 0.29 11.5 0.0 2.6 2 1 1 3 3 3 0 Polyphosphate kinase N-terminal domain PRKG1_interact PF15898.5 EPE24643.1 - 0.1 13.5 2.8 0.99 10.3 0.2 2.7 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain TLP-20 PF06088.11 EPE24644.1 - 1.3 8.9 12.1 4.8 7.0 3.7 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) GST_N_3 PF13417.6 EPE24648.1 - 6.5e-15 55.3 0.0 1.2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EPE24648.1 - 4.3e-12 46.1 0.2 1e-11 44.9 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EPE24648.1 - 2.6e-11 43.6 0.0 6.1e-11 42.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EPE24648.1 - 5.8e-11 42.6 0.0 1.2e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EPE24648.1 - 9.9e-11 41.7 0.0 2.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPE24648.1 - 0.00035 20.6 0.1 0.00067 19.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3791 PF12668.7 EPE24648.1 - 0.019 15.0 0.1 0.058 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) GST_N_4 PF17172.4 EPE24648.1 - 0.038 14.7 0.0 0.073 13.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Plant_NMP1 PF06694.11 EPE24648.1 - 0.099 11.7 0.1 0.14 11.3 0.1 1.1 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) DUF3217 PF11506.8 EPE24648.1 - 0.39 10.7 1.7 0.36 10.8 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3217) TPR_12 PF13424.6 EPE24649.1 - 3e-18 65.9 30.5 1.4e-05 25.2 2.0 6.5 4 1 5 9 9 9 7 Tetratricopeptide repeat TPR_20 PF14561.6 EPE24649.1 - 6.7e-16 58.4 11.3 0.005 17.1 0.1 7.6 1 1 5 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EPE24649.1 - 1.5e-15 56.1 6.7 0.088 13.1 0.0 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 EPE24649.1 - 2e-15 56.3 5.7 0.44 11.3 0.1 8.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EPE24649.1 - 5.5e-15 55.6 13.6 0.0015 19.0 0.6 7.0 3 2 3 7 7 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 EPE24649.1 - 8.1e-14 51.0 17.2 0.36 10.8 0.1 8.8 10 0 0 10 10 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE24649.1 - 6.2e-13 48.8 18.3 0.011 15.9 0.0 7.2 2 1 4 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EPE24649.1 - 7.4e-13 47.6 6.1 2.4 8.5 0.0 8.7 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 EPE24649.1 - 5.6e-12 45.4 11.5 0.96 10.4 0.3 7.7 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_4 PF07721.14 EPE24649.1 - 9.9e-11 41.2 13.0 0.093 13.4 0.4 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EPE24649.1 - 2e-09 37.9 2.0 0.0018 18.9 0.8 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EPE24649.1 - 7e-09 35.1 13.6 2.6 8.3 0.2 7.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EPE24649.1 - 6e-08 32.2 8.7 2.7 7.9 0.0 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat NB-ARC PF00931.22 EPE24649.1 - 8.5e-08 31.7 0.0 1.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_17 PF13431.6 EPE24649.1 - 2.5e-07 30.6 6.0 5.5 7.6 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.20 EPE24649.1 - 8.2e-05 22.6 0.8 7.4 7.1 0.0 7.1 9 0 0 9 9 8 0 PPR repeat RPN7 PF10602.9 EPE24649.1 - 0.00047 19.9 9.4 6.7 6.4 0.4 4.9 2 1 3 5 5 5 0 26S proteasome subunit RPN7 TPR_9 PF13371.6 EPE24649.1 - 0.0024 18.0 6.9 3.6 7.8 0.5 5.4 2 1 4 6 6 6 1 Tetratricopeptide repeat AAA_16 PF13191.6 EPE24649.1 - 0.0039 17.6 0.6 0.058 13.8 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain Abhydrolase_6 PF12697.7 EPE24649.1 - 0.0043 17.7 0.1 0.016 15.9 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Vps39_1 PF10366.9 EPE24649.1 - 0.0077 16.5 12.7 7.4 6.9 0.3 5.2 2 2 4 6 6 6 0 Vacuolar sorting protein 39 domain 1 LCAT PF02450.15 EPE24649.1 - 0.0095 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase CbiA PF01656.23 EPE24649.1 - 0.02 14.9 0.0 0.068 13.2 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain LIDHydrolase PF10230.9 EPE24649.1 - 0.024 14.2 0.2 0.38 10.3 0.0 2.9 3 0 0 3 3 3 0 Lipid-droplet associated hydrolase NACHT PF05729.12 EPE24649.1 - 0.029 14.3 0.0 0.1 12.5 0.0 1.9 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 EPE24649.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NTPase Abhydrolase_9 PF10081.9 EPE24649.1 - 0.062 12.4 0.1 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta-hydrolase family Ser_hydrolase PF06821.13 EPE24649.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase DUF726 PF05277.12 EPE24649.1 - 0.11 11.5 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) PGAP1 PF07819.13 EPE24649.1 - 0.13 11.9 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein DUF384 PF04064.13 EPE24649.1 - 0.42 10.5 5.4 38 4.2 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF384) DUF1996 PF09362.10 EPE24655.1 - 1.9e-74 250.6 0.3 2.8e-74 250.1 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) CPSF_A PF03178.15 EPE24656.1 - 5e-92 308.7 0.0 4.7e-91 305.5 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.9 EPE24656.1 - 1e-21 77.1 0.0 2.6e-21 75.8 0.0 1.7 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.16 EPE24657.1 - 3e-19 69.3 1.5 3e-19 69.3 1.5 2.7 2 1 1 3 3 3 2 LMBR1-like membrane protein DUF3671 PF12420.8 EPE24657.1 - 0.1 12.7 0.1 0.1 12.7 0.1 3.6 4 1 1 5 5 5 0 Protein of unknown function TMEM208_SND2 PF05620.11 EPE24657.1 - 3 7.6 0.0 3 7.6 0.0 4.0 5 1 1 6 6 6 0 SRP-independent targeting protein 2/TMEM208 WD40 PF00400.32 EPE24658.1 - 3.4e-10 40.3 6.7 0.0082 17.0 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE24658.1 - 0.00011 22.4 1.5 5 7.5 0.0 5.6 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_N PF01194.17 EPE24659.1 - 2.7e-31 107.7 1.9 3.3e-31 107.4 1.9 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 EPE24659.1 - 0.059 13.6 0.6 0.11 12.8 0.6 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Helo_like_N PF17111.5 EPE24660.1 - 0.62 9.4 3.8 2.8 7.2 0.1 2.6 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins 4F5 PF04419.14 EPE24661.1 - 0.00053 20.8 6.7 0.00092 20.0 6.7 1.4 1 0 0 1 1 1 1 4F5 protein family CBP_BcsO PF17037.5 EPE24661.1 - 0.019 15.1 0.1 0.025 14.8 0.1 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO SAND PF01342.21 EPE24661.1 - 0.028 14.1 1.2 0.04 13.6 1.0 1.4 1 1 0 1 1 1 0 SAND domain AT_hook PF02178.19 EPE24662.1 - 2.5e-05 23.6 36.2 0.077 12.9 0.6 7.3 6 0 0 6 6 6 5 AT hook motif HHH PF00633.23 EPE24662.1 - 0.067 13.1 1.0 0.22 11.5 0.1 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif Ank_2 PF12796.7 EPE24664.1 - 1.2e-100 330.2 15.6 1.6e-12 47.9 0.1 11.7 4 2 9 13 13 13 11 Ankyrin repeats (3 copies) Ank PF00023.30 EPE24664.1 - 5.4e-74 241.6 20.9 2.8e-06 27.5 0.0 18.4 18 0 0 18 18 18 17 Ankyrin repeat Ank_4 PF13637.6 EPE24664.1 - 1.2e-66 220.3 25.7 1.4e-07 31.9 0.1 16.6 6 4 11 19 19 19 15 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE24664.1 - 9.7e-65 206.9 10.9 0.0021 18.4 0.0 21.1 20 1 1 21 21 21 13 Ankyrin repeat Ank_5 PF13857.6 EPE24664.1 - 9.8e-63 207.4 22.6 3.9e-06 27.0 0.0 15.9 7 6 10 17 17 17 13 Ankyrin repeats (many copies) SPRY PF00622.28 EPE24664.1 - 6.6e-15 55.3 0.1 1.8e-14 53.9 0.1 1.7 1 0 0 1 1 1 1 SPRY domain Peptidase_S8 PF00082.22 EPE24666.1 - 6.3e-09 35.5 2.2 1.5e-08 34.3 2.2 1.5 1 1 0 1 1 1 1 Subtilase family Ank_4 PF13637.6 EPE24666.1 - 0.0012 19.3 0.0 0.34 11.5 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE24666.1 - 0.012 16.1 0.0 3 8.5 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) SRC-1 PF08832.10 EPE24666.1 - 0.083 14.0 0.4 0.38 11.8 0.4 2.1 1 0 0 1 1 1 0 Steroid receptor coactivator DIOX_N PF14226.6 EPE24667.1 - 1.1e-30 106.9 0.0 1.7e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPE24667.1 - 1.9e-13 50.8 0.0 3.4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NPR2 PF06218.11 EPE24669.1 - 4e-139 464.2 7.9 2.1e-115 386.0 5.0 2.8 1 1 1 2 2 2 2 Nitrogen permease regulator 2 Methyltransf_16 PF10294.9 EPE24670.1 - 1.3e-16 60.8 0.0 2.2e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 EPE24670.1 - 0.024 14.5 0.0 0.068 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EPE24670.1 - 0.049 13.2 0.0 1.7 8.2 0.0 2.9 3 1 1 4 4 4 0 Methyltransferase small domain IBR PF01485.21 EPE24671.1 - 4.2e-07 30.1 5.5 4.2e-07 30.1 5.5 3.6 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Presenilin PF01080.17 EPE24671.1 - 1 8.0 3.8 1.5 7.5 3.8 1.1 1 0 0 1 1 1 0 Presenilin RAP1 PF07218.11 EPE24671.1 - 2.4 6.4 8.6 3.3 5.9 8.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_M3 PF01432.20 EPE24672.1 - 2.2e-101 340.4 0.0 2.9e-101 340.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Glyco_hydro_76 PF03663.14 EPE24673.1 - 1.1e-21 77.8 5.2 3.8e-15 56.3 0.7 3.3 2 2 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EPE24673.1 - 0.01 14.9 0.2 0.02 14.0 0.2 1.4 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 DUF1910 PF08928.10 EPE24673.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) Hpr_kinase_C PF07475.12 EPE24673.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain FAD_binding_3 PF01494.19 EPE24674.1 - 4.7e-15 55.7 3.9 3.8e-12 46.1 0.9 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EPE24674.1 - 5.2e-07 29.2 2.4 0.00046 19.5 0.2 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE24674.1 - 9.2e-07 28.3 0.3 3.3e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EPE24674.1 - 3.4e-05 24.3 0.1 0.15 12.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE24674.1 - 3.7e-05 23.8 0.2 0.00014 22.0 0.2 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EPE24674.1 - 8e-05 22.2 0.7 0.00036 20.0 0.7 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EPE24674.1 - 0.0008 18.6 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EPE24674.1 - 0.002 16.9 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EPE24674.1 - 0.003 16.9 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EPE24674.1 - 0.0035 17.0 4.5 0.28 10.7 0.2 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase RRM_1 PF00076.22 EPE24675.1 - 1.3e-16 60.2 0.0 2e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EPE24675.1 - 0.002 18.2 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif BTB PF00651.31 EPE24676.1 - 0.011 15.9 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain DDHD PF02862.17 EPE24676.1 - 0.062 13.5 0.0 0.07 13.3 0.0 1.1 1 0 0 1 1 1 0 DDHD domain BTB PF00651.31 EPE24677.1 - 0.00043 20.5 0.0 0.0028 17.9 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain BTB PF00651.31 EPE24678.1 - 0.017 15.3 0.0 0.053 13.8 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain BTB PF00651.31 EPE24679.1 - 0.0021 18.3 0.0 0.0098 16.1 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Thioredoxin_6 PF13848.6 EPE24679.1 - 0.01 15.8 0.3 0.025 14.5 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain Malic_M PF03949.15 EPE24681.1 - 8e-92 307.1 0.0 1.2e-91 306.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EPE24681.1 - 6e-67 225.0 0.0 1.1e-66 224.1 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Helicase_IV_N PF12462.8 EPE24681.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal zf-C2H2_4 PF13894.6 EPE24682.1 - 9e-07 29.2 3.1 0.0057 17.4 0.1 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EPE24682.1 - 0.00026 21.3 2.7 0.011 16.1 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type Glyco_hydro_115 PF15979.5 EPE24683.1 - 1.4e-141 471.8 1.2 1.4e-141 471.8 1.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 EPE24683.1 - 1.9e-58 197.1 0.2 3.8e-58 196.1 0.2 1.5 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Glyco_hydro_67N PF03648.14 EPE24683.1 - 0.017 15.4 0.0 0.054 13.8 0.0 1.9 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus CAF-1_p150 PF11600.8 EPE24684.1 - 0.002 17.9 10.9 0.0026 17.5 10.9 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Exonuc_VII_L PF02601.15 EPE24684.1 - 0.43 10.1 6.0 0.54 9.8 6.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Asp-B-Hydro_N PF05279.11 EPE24684.1 - 1.2 9.1 11.3 1.6 8.7 11.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PAP2_3 PF14378.6 EPE24685.1 - 6.9e-32 110.7 12.9 3.5e-16 59.5 0.1 3.3 3 0 0 3 3 3 3 PAP2 superfamily PAP2_C PF14360.6 EPE24685.1 - 0.03 14.9 1.9 0.05 14.1 0.1 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal QVR PF17064.5 EPE24688.1 - 0.051 13.8 0.6 0.12 12.7 0.3 1.7 1 1 0 1 1 1 0 Sleepless protein GRDP-like PF07173.12 EPE24689.1 - 1.8e-15 57.9 0.0 9.1e-11 42.6 0.0 2.8 2 1 1 3 3 3 2 Glycine-rich domain-containing protein-like DUF1045 PF06299.12 EPE24689.1 - 0.0019 18.2 0.2 0.0055 16.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1045) RIFIN PF02009.16 EPE24690.1 - 0.0036 17.2 0.8 0.0067 16.4 0.8 1.4 1 0 0 1 1 1 1 Rifin DUF2070 PF09843.9 EPE24690.1 - 0.08 11.2 3.7 0.13 10.5 3.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1180 PF06679.12 EPE24690.1 - 1.5 9.2 10.0 0.17 12.3 5.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) ATP-synt_B PF00430.18 EPE24690.1 - 4.8 7.3 7.5 15 5.7 7.5 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) NIF PF03031.18 EPE24693.1 - 1.7e-39 135.1 0.0 2.4e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PhoLip_ATPase_C PF16212.5 EPE24694.1 - 1.2e-68 231.6 22.8 1.2e-68 231.6 22.8 2.4 3 1 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EPE24694.1 - 3.3e-20 71.5 1.0 3.3e-20 71.5 1.0 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EPE24694.1 - 2.2e-14 54.2 2.3 7.9e-07 29.6 0.3 3.3 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EPE24694.1 - 2.6e-12 46.7 0.0 7.6e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 EPE24694.1 - 5.3e-12 45.7 0.0 2.3e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) HAD_2 PF13419.6 EPE24694.1 - 2.3e-05 24.6 0.1 5.4e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EPE24694.1 - 3.6e-05 23.6 0.2 0.026 14.3 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase FixP_N PF14715.6 EPE24694.1 - 0.46 10.3 5.0 1.9 8.3 5.0 2.1 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP ICMT PF04140.14 EPE24695.1 - 6e-10 39.4 1.4 3.5e-08 33.8 0.1 2.6 1 1 1 2 2 2 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EPE24695.1 - 1e-05 25.8 0.2 1e-05 25.8 0.2 2.8 2 1 1 3 3 3 1 Phospholipid methyltransferase Clr5 PF14420.6 EPE24696.1 - 0.025 14.8 0.2 0.066 13.5 0.0 1.8 2 0 0 2 2 2 0 Clr5 domain AAA PF00004.29 EPE24698.1 - 4.1e-20 72.5 0.0 8.3e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE24698.1 - 0.0056 17.1 0.1 0.0056 17.1 0.1 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EPE24698.1 - 0.066 13.5 0.3 0.31 11.3 0.1 2.2 1 1 1 2 2 2 0 AAA domain DUF3145 PF11343.8 EPE24698.1 - 0.066 12.8 0.4 0.89 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) AAA_5 PF07728.14 EPE24698.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EPE24698.1 - 0.28 11.7 2.6 1.5 9.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain BTB PF00651.31 EPE24699.1 - 1.9e-07 31.3 0.2 0.0054 17.0 0.0 3.1 3 0 0 3 3 3 2 BTB/POZ domain BTB PF00651.31 EPE24700.1 - 6.2e-06 26.4 0.0 0.0024 18.1 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 EPE24701.1 - 5.6e-06 26.6 0.3 0.0016 18.6 0.1 2.1 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 EPE24703.1 - 1.8e-07 31.4 1.7 4.7e-06 26.8 1.7 2.3 1 1 0 1 1 1 1 BTB/POZ domain Peptidase_S8 PF00082.22 EPE24704.1 - 3e-31 108.8 14.8 6.4e-31 107.7 14.8 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EPE24704.1 - 2.9e-08 34.3 0.1 6.8e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Methyltrans_SAM PF10672.9 EPE24704.1 - 0.23 10.6 0.2 0.37 9.9 0.2 1.3 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase VPDSG-CTERM PF18205.1 EPE24706.1 - 0.48 10.3 5.3 0.94 9.4 5.3 1.5 1 0 0 1 1 1 0 VPDSG-CTERM motif CCDC14 PF15254.6 EPE24706.1 - 5.4 5.5 4.9 6.8 5.2 4.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 Acetyltransf_1 PF00583.25 EPE24707.1 - 8.3e-07 29.3 0.0 1.5e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE24707.1 - 2.4e-05 24.3 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE24707.1 - 0.00013 22.3 0.0 0.00023 21.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 EPE24707.1 - 0.0015 18.2 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_9 PF13527.7 EPE24707.1 - 0.0093 16.0 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE24707.1 - 0.061 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein ADH_N PF08240.12 EPE24708.1 - 8e-26 90.1 4.8 8.4e-26 90.0 3.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE24708.1 - 3.3e-16 59.4 0.0 5.4e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 EPE24708.1 - 0.007 16.1 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.6 EPE24708.1 - 0.023 15.8 0.0 0.041 14.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Zip PF02535.22 EPE24709.1 - 7.9e-53 179.8 1.0 1.5e-52 178.9 1.0 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Pec_lyase_C PF00544.19 EPE24710.1 - 6.3e-10 39.0 10.6 2.3e-08 33.9 10.6 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EPE24710.1 - 0.0057 16.5 21.1 0.01 15.7 10.1 2.4 1 1 1 2 2 2 2 Right handed beta helix region Latrotoxin_C PF15658.6 EPE24710.1 - 0.11 12.3 0.1 0.29 10.9 0.1 1.7 1 0 0 1 1 1 0 Latrotoxin C-terminal domain Methyltransf_11 PF08241.12 EPE24714.1 - 3.1e-18 66.2 0.0 4.7e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE24714.1 - 1.7e-16 60.7 0.0 2.9e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE24714.1 - 1.8e-15 57.1 0.0 2.3e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE24714.1 - 9e-15 54.8 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE24714.1 - 1.3e-11 45.1 0.0 1.9e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE24714.1 - 2e-05 24.0 0.0 2.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 EPE24714.1 - 3.3e-05 23.0 0.0 4.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 EPE24714.1 - 0.0001 22.0 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.20 EPE24714.1 - 0.00018 20.9 0.0 0.00025 20.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EPE24714.1 - 0.00035 20.1 0.0 0.00047 19.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 EPE24714.1 - 0.00061 19.3 0.0 0.00092 18.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 EPE24714.1 - 0.00091 18.8 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EPE24714.1 - 0.096 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 EPE24714.1 - 0.21 11.4 0.0 0.52 10.1 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase Cons_hypoth95 PF03602.15 EPE24714.1 - 0.21 11.2 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Pkinase_Tyr PF07714.17 EPE24716.1 - 9.3e-16 57.9 0.0 6e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EPE24716.1 - 1.6e-15 57.2 0.0 2.4e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 EPE24716.1 - 2e-15 56.3 4.7 3.5e-07 29.9 0.7 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EPE24716.1 - 1.8e-10 40.9 4.8 0.008 16.6 0.5 4.7 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) Kdo PF06293.14 EPE24716.1 - 6.8e-07 28.9 0.1 1.1e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_1 PF00560.33 EPE24716.1 - 0.00058 20.0 7.4 0.64 10.8 0.2 5.1 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.6 EPE24716.1 - 0.0026 17.3 0.6 0.013 15.0 0.1 2.2 2 1 0 2 2 2 1 Leucine-rich repeat Kinase-like PF14531.6 EPE24716.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EPE24716.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_6 PF13516.6 EPE24716.1 - 0.55 10.4 4.2 22 5.4 0.2 3.3 3 0 0 3 3 3 0 Leucine Rich repeat p450 PF00067.22 EPE24717.1 - 7.4e-66 222.8 0.0 9.8e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_6 PF00970.24 EPE24718.1 - 2.1e-28 98.6 0.0 3.2e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EPE24718.1 - 3.1e-24 85.7 0.0 5.1e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_9 PF08021.11 EPE24718.1 - 0.0022 18.2 0.0 0.0044 17.2 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain NAD_binding_6 PF08030.12 EPE24718.1 - 0.0024 18.0 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Tudor_FRX1 PF18336.1 EPE24718.1 - 0.14 12.1 0.0 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 Fragile X mental retardation Tudor domain 3HCDH_N PF02737.18 EPE24719.1 - 5.9e-30 104.5 0.0 8.6e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EPE24719.1 - 5.4e-15 55.8 0.0 1.2e-14 54.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF5050 PF16472.5 EPE24719.1 - 0.0022 17.3 0.1 1.2 8.3 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF5050) NAD_binding_2 PF03446.15 EPE24719.1 - 0.0049 17.0 0.0 0.0093 16.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 EPE24719.1 - 0.0069 16.4 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 EPE24719.1 - 0.041 13.2 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ldl_recept_b PF00058.17 EPE24719.1 - 0.046 14.2 0.1 3.5 8.2 0.0 3.7 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B AlaDh_PNT_C PF01262.21 EPE24719.1 - 0.075 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HET PF06985.11 EPE24720.1 - 1.2e-27 97.1 0.0 2.2e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Actin PF00022.19 EPE24721.1 - 1e-134 449.2 0.0 1.2e-134 449.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EPE24721.1 - 1.5e-07 30.6 0.0 0.024 13.5 0.0 3.1 2 1 1 3 3 3 3 MreB/Mbl protein D-ser_dehydrat PF14031.6 EPE24722.1 - 9.5e-25 87.1 0.0 5e-24 84.8 0.0 2.1 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EPE24722.1 - 9.1e-17 61.4 0.0 1.3e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Pkinase PF00069.25 EPE24724.1 - 2.7e-11 43.4 0.4 1.5e-07 31.1 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 EPE24724.1 - 0.0094 15.3 0.1 0.021 14.2 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EPE24724.1 - 0.068 12.4 0.0 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase MFS_1 PF07690.16 EPE24725.1 - 4.2e-47 160.8 56.7 6.4e-46 156.9 55.2 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE24725.1 - 2.1e-16 59.8 8.8 2.1e-16 59.8 8.8 3.3 4 0 0 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.13 EPE24725.1 - 9.1e-15 54.1 24.3 3.8e-14 52.0 24.3 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) IncD PF17628.2 EPE24725.1 - 8 6.2 10.0 0.42 10.4 0.8 3.0 3 0 0 3 3 3 0 Inclusion membrane protein D CorA PF01544.18 EPE24726.1 - 0.00053 19.4 1.9 0.0011 18.4 1.2 1.7 1 1 0 2 2 2 1 CorA-like Mg2+ transporter protein BatD PF13584.6 EPE24726.1 - 0.013 14.3 0.1 0.019 13.8 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance Saf_2TM PF18303.1 EPE24726.1 - 0.021 14.4 0.2 0.037 13.6 0.2 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF4381 PF14316.6 EPE24726.1 - 0.047 13.9 0.1 0.047 13.9 0.1 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF3671 PF12420.8 EPE24727.1 - 1.8 8.7 10.2 12 6.0 1.1 3.1 3 0 0 3 3 3 0 Protein of unknown function F-box-like PF12937.7 EPE24728.1 - 3.6e-11 42.8 0.0 6.3e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE24728.1 - 0.00025 20.8 0.1 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 F-box domain MIT PF04212.18 EPE24728.1 - 0.021 14.9 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain F-box_4 PF15966.5 EPE24728.1 - 0.078 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 F-box Mito_carr PF00153.27 EPE24729.1 - 2.8e-65 216.3 0.5 9.3e-22 76.8 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein UDG PF03167.19 EPE24730.1 - 3.3e-21 75.9 0.1 6.1e-21 75.0 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Sld3_N PF18523.1 EPE24730.1 - 0.067 13.3 0.7 0.15 12.2 0.7 1.5 1 0 0 1 1 1 0 Sld3 N-terminal domain Macoilin PF09726.9 EPE24730.1 - 1.6 7.2 7.5 2.3 6.7 7.5 1.2 1 0 0 1 1 1 0 Macoilin family DUF3140 PF11338.8 EPE24731.1 - 3.4e-32 110.7 1.6 4e-32 110.5 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) DUF1843 PF08898.10 EPE24731.1 - 0.027 15.0 0.2 0.043 14.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DUF1708 PF08101.11 EPE24732.1 - 9e-176 585.3 0.0 1.3e-175 584.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) SRF-TF PF00319.18 EPE24733.1 - 7.8e-24 82.9 0.2 1.2e-23 82.3 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HET PF06985.11 EPE24734.1 - 2e-35 122.3 1.9 3.8e-35 121.4 1.9 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 EPE24735.1 - 1.2e-19 70.5 36.5 1.2e-19 70.5 36.5 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EPE24735.1 - 5.9e-07 29.1 12.6 5.9e-07 29.1 12.6 2.1 1 1 2 3 3 3 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 EPE24735.1 - 0.001 18.0 15.1 0.023 13.6 4.4 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter LapA_dom PF06305.11 EPE24735.1 - 0.032 14.0 0.0 0.032 14.0 0.0 3.5 3 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Ribosomal_L14 PF00238.19 EPE24736.1 - 2.6e-33 114.7 0.0 3.1e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hist_deacetyl PF00850.19 EPE24737.1 - 5.3e-83 279.0 0.2 1.8e-82 277.3 0.0 1.8 2 0 0 2 2 2 1 Histone deacetylase domain JAB PF01398.21 EPE24738.1 - 1.1e-32 112.5 0.0 2.2e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EPE24738.1 - 9.5e-12 45.3 0.3 2.1e-11 44.2 0.3 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EPE24738.1 - 1.1e-07 31.6 0.0 2.6e-07 30.4 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain DUF2288 PF10052.9 EPE24738.1 - 0.21 11.7 0.8 0.47 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2288) RasGAP PF00616.19 EPE24739.1 - 3.2e-55 187.1 0.1 1.1e-54 185.4 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EPE24739.1 - 8.2e-49 165.3 2.6 2.7e-48 163.6 2.6 2.0 1 0 0 1 1 1 1 RasGAP C-terminus IQ PF00612.27 EPE24739.1 - 1.1e-12 46.5 20.9 4 7.5 0.0 12.5 13 0 0 13 13 13 5 IQ calmodulin-binding motif CH PF00307.31 EPE24739.1 - 7.4e-11 42.2 0.0 2.6e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain DNA_repr_REX1B PF14966.6 EPE24739.1 - 0.038 14.7 4.3 0.46 11.2 0.6 3.7 1 1 1 2 2 2 0 DNA repair REX1-B IMPDH PF00478.25 EPE24740.1 - 2e-125 418.4 7.3 2.3e-125 418.2 7.3 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EPE24740.1 - 2.3e-16 60.0 0.1 1.5e-08 35.0 0.1 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 EPE24740.1 - 6e-08 32.5 2.5 0.0064 15.9 1.0 2.7 3 0 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 EPE24740.1 - 4.3e-07 29.3 1.3 7.7e-06 25.2 0.4 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 EPE24740.1 - 0.0078 15.7 1.6 0.041 13.3 1.1 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein YpsA PF06908.11 EPE24740.1 - 0.0084 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 YspA SLOG family PK PF00224.21 EPE24740.1 - 0.0097 14.8 0.0 0.041 12.8 0.0 2.0 2 1 0 2 2 2 1 Pyruvate kinase, barrel domain OrfB_IS605 PF01385.19 EPE24742.1 - 0.051 13.8 0.2 0.088 13.0 0.2 1.4 1 0 0 1 1 1 0 Probable transposase HisK_N PF09385.10 EPE24742.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase N terminal DUF2730 PF10805.8 EPE24743.1 - 0.18 11.9 0.2 1.7 8.8 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DUF2371 PF10177.9 EPE24743.1 - 0.18 12.0 0.2 0.65 10.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) adh_short PF00106.25 EPE24744.1 - 1.2e-22 80.3 0.0 1.5e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE24744.1 - 7.9e-15 55.1 0.0 1e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE24744.1 - 3.6e-06 27.0 0.0 4.8e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE24744.1 - 3.3e-05 23.5 0.0 6.1e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE24744.1 - 0.02 14.3 0.4 0.1 12.0 0.4 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sigma54_activ_2 PF14532.6 EPE24744.1 - 0.084 13.0 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain EthD PF07110.11 EPE24745.1 - 1.4e-08 35.7 0.3 1.9e-08 35.3 0.3 1.2 1 0 0 1 1 1 1 EthD domain Thioredoxin_16 PF18569.1 EPE24746.1 - 0.0057 16.7 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain BTB PF00651.31 EPE24746.1 - 0.0079 16.4 0.7 0.029 14.6 0.3 2.1 3 0 0 3 3 3 1 BTB/POZ domain MtrG PF04210.13 EPE24746.1 - 0.059 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G BTB PF00651.31 EPE24747.1 - 2.2e-07 31.1 0.3 0.0013 19.0 0.1 2.6 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 EPE24748.1 - 3e-06 27.4 1.1 0.0088 16.3 0.0 3.1 3 1 1 4 4 4 2 BTB/POZ domain TFR_dimer PF04253.15 EPE24752.1 - 4.4e-32 110.7 0.1 8e-32 109.9 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EPE24752.1 - 9.4e-18 64.6 0.0 2.3e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EPE24752.1 - 4.1e-08 33.1 0.6 1e-07 31.9 0.1 2.0 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 EPE24752.1 - 0.093 12.2 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Nicastrin MFS_1 PF07690.16 EPE24753.1 - 3e-32 111.9 32.8 8.3e-27 94.0 10.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE24753.1 - 5.9e-11 41.9 3.0 5.9e-11 41.9 3.0 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter O-ag_pol_Wzy PF14296.6 EPE24753.1 - 0.94 8.1 7.8 0.57 8.8 5.0 2.0 2 1 0 2 2 2 0 O-antigen polysaccharide polymerase Wzy MFS_1 PF07690.16 EPE24755.1 - 5.8e-29 101.1 35.9 5.8e-29 101.1 35.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.6 EPE24756.1 - 1.7e-18 67.5 0.1 4e-18 66.3 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPE24756.1 - 7.9e-17 61.6 0.0 1.6e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HET PF06985.11 EPE24757.1 - 5.8e-36 124.0 0.6 1e-35 123.3 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sortilin-Vps10 PF15902.5 EPE24758.1 - 0.0012 17.7 0.0 0.015 14.2 0.0 2.0 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, BNR_2 PF13088.6 EPE24758.1 - 0.0024 17.2 0.1 0.03 13.6 0.0 2.1 2 0 0 2 2 2 1 BNR repeat-like domain BNR PF02012.20 EPE24758.1 - 0.018 15.0 0.8 3.4 8.0 0.2 3.5 2 0 0 2 2 2 0 BNR/Asp-box repeat Aldo_ket_red PF00248.21 EPE24759.1 - 5.8e-49 166.9 0.0 6.7e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_25 PF13649.6 EPE24760.1 - 0.012 16.3 0.1 0.56 10.9 0.1 2.4 1 1 0 1 1 1 0 Methyltransferase domain Aldo_ket_red PF00248.21 EPE24761.1 - 4.2e-59 200.1 0.0 5.2e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.22 EPE24762.1 - 3.9e-47 161.0 0.0 5.1e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 V-ATPase_H_C PF11698.8 EPE24762.1 - 0.13 12.4 0.0 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 V-ATPase subunit H Peptidase_A4 PF01828.17 EPE24763.1 - 5.9e-14 52.0 2.6 7.4e-14 51.7 2.6 1.2 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_A4 PF01828.17 EPE24764.1 - 4.8e-18 65.4 0.2 6.2e-18 65.0 0.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family Abhydrolase_1 PF00561.20 EPE24766.1 - 4e-25 88.9 0.2 6.5e-25 88.2 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE24766.1 - 9.7e-19 68.8 0.9 1.4e-18 68.4 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE24766.1 - 8.7e-12 44.8 0.1 1.8e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EPE24766.1 - 1.4e-06 28.4 0.0 2.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.11 EPE24766.1 - 0.00062 18.9 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.7 EPE24766.1 - 0.0036 16.3 0.0 0.0056 15.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 EPE24766.1 - 0.0054 16.3 0.0 0.033 13.8 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family PGAP1 PF07819.13 EPE24766.1 - 0.02 14.6 0.1 0.044 13.5 0.1 1.5 2 0 0 2 2 2 0 PGAP1-like protein EHN PF06441.12 EPE24766.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DUF5541 PF17695.1 EPE24767.1 - 0.11 12.9 0.2 5.6 7.4 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5541) SLAC1 PF03595.17 EPE24768.1 - 4.1e-89 299.1 52.6 4.7e-89 298.8 52.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF948 PF06103.11 EPE24769.1 - 0.012 15.8 0.5 0.05 13.9 0.5 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Ank_2 PF12796.7 EPE24770.1 - 3.4e-27 94.9 0.0 5.7e-07 30.0 0.0 7.0 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE24770.1 - 8.5e-22 77.2 0.0 0.05 14.2 0.0 10.6 5 2 7 12 12 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE24770.1 - 1.3e-21 74.3 0.1 0.36 11.5 0.0 11.4 12 0 0 12 12 12 6 Ankyrin repeat Ank PF00023.30 EPE24770.1 - 6.6e-12 45.3 3.6 0.58 10.7 0.0 8.7 11 1 0 11 11 11 3 Ankyrin repeat Ank_5 PF13857.6 EPE24770.1 - 2.4e-11 43.6 0.5 0.4 11.1 0.0 8.0 7 2 2 9 9 9 3 Ankyrin repeats (many copies) UBA_4 PF14555.6 EPE24770.1 - 0.21 11.5 0.2 11 5.9 0.0 2.5 2 0 0 2 2 2 0 UBA-like domain ATP-synt_ab_Xtn PF16886.5 EPE24771.1 - 0.083 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 ATPsynthase alpha/beta subunit N-term extension ABC_tran PF00005.27 EPE24772.1 - 3.6e-46 157.1 0.6 1.3e-25 90.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EPE24772.1 - 4e-25 88.7 52.8 9.3e-16 57.9 25.1 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 EPE24772.1 - 1.3e-20 74.5 2.6 8.7e-05 22.5 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EPE24772.1 - 8.4e-08 31.9 3.3 0.0011 18.7 0.6 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EPE24772.1 - 3.7e-07 29.8 3.3 0.16 11.4 0.0 3.6 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EPE24772.1 - 9.2e-07 28.9 0.2 0.034 14.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC2_membrane PF01061.24 EPE24772.1 - 2.2e-05 24.0 16.0 2.2e-05 24.0 16.0 4.5 5 1 0 5 5 4 1 ABC-2 type transporter AAA_23 PF13476.6 EPE24772.1 - 7.1e-05 23.4 5.3 0.15 12.6 0.6 2.5 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 EPE24772.1 - 0.00045 19.9 0.4 0.27 10.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EPE24772.1 - 0.00054 20.4 0.2 1.3 9.3 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 EPE24772.1 - 0.00095 19.0 0.1 0.81 9.3 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain DUF4162 PF13732.6 EPE24772.1 - 0.005 17.5 0.0 0.12 13.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_22 PF13401.6 EPE24772.1 - 0.0056 16.9 0.3 3.8 7.8 0.1 3.4 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EPE24772.1 - 0.0068 16.1 2.5 2.2 8.0 0.3 2.7 2 1 0 2 2 2 2 AAA domain SRP54 PF00448.22 EPE24772.1 - 0.048 13.3 0.9 10 5.7 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EPE24772.1 - 0.075 12.3 0.3 7.8 5.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 EPE24772.1 - 0.11 12.1 1.1 14 5.2 0.1 2.7 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EPE24772.1 - 0.15 12.4 0.0 21 5.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 EPE24772.1 - 0.2 11.9 3.7 7.3 6.8 0.5 3.2 3 0 0 3 3 3 0 AAA domain AIG1 PF04548.16 EPE24772.1 - 5.7 6.2 4.8 5.4 6.3 1.4 2.3 2 0 0 2 2 2 0 AIG1 family Vta1 PF04652.16 EPE24773.1 - 1.6e-54 183.8 1.6 3.3e-54 182.8 0.5 1.8 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 EPE24773.1 - 2.3e-17 62.4 0.4 5.3e-17 61.2 0.4 1.6 1 0 0 1 1 1 1 Vta1 C-terminal domain Thioredoxin PF00085.20 EPE24774.1 - 5.6e-32 109.8 0.0 2.1e-25 88.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 EPE24774.1 - 1.9e-06 27.5 0.0 3.2e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EPE24774.1 - 6.2e-05 23.4 3.9 0.19 12.2 0.1 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EPE24774.1 - 0.0027 18.0 0.1 33 4.9 0.0 4.4 3 2 1 4 4 4 0 Thioredoxin-like HyaE PF07449.11 EPE24774.1 - 0.021 14.8 0.0 0.9 9.5 0.0 3.0 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 EPE24774.1 - 0.07 13.1 0.0 0.78 9.7 0.0 2.2 2 0 0 2 2 2 0 AhpC/TSA family TraF PF13728.6 EPE24774.1 - 0.24 11.2 0.0 0.24 11.2 0.0 4.2 4 1 0 4 4 4 0 F plasmid transfer operon protein Presenilin PF01080.17 EPE24774.1 - 1.8 7.2 2.8 3.3 6.4 2.8 1.3 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 EPE24774.1 - 4.7 5.9 5.0 11 4.8 0.1 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter Pap_E4 PF02711.14 EPE24774.1 - 8.4 7.4 6.9 3.7 8.6 2.5 2.6 3 0 0 3 3 3 0 E4 protein RNase_PH PF01138.21 EPE24775.1 - 1.4e-33 116.2 0.1 2e-33 115.7 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ER_lumen_recept PF00810.18 EPE24776.1 - 6.1e-43 147.2 6.7 1e-42 146.4 6.7 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EPE24776.1 - 0.0051 16.6 7.6 0.027 14.3 0.0 3.1 3 0 0 3 3 3 2 PQ loop repeat DUF4234 PF14018.6 EPE24776.1 - 1.1 9.5 9.8 3.8 7.7 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) MreB_Mbl PF06723.13 EPE24777.1 - 0.0014 17.5 0.1 0.0028 16.5 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Nterm_IS4 PF13006.7 EPE24778.1 - 0.015 15.5 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal DcuC PF03606.15 EPE24778.1 - 0.13 10.7 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier GAS PF13851.6 EPE24780.1 - 0.01 15.2 3.9 0.026 13.9 3.9 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 EPE24780.1 - 0.059 13.5 5.2 0.14 12.2 5.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus S6OS1 PF15676.5 EPE24780.1 - 0.086 11.3 4.4 0.18 10.3 0.5 2.1 2 0 0 2 2 2 0 Six6 opposite strand transcript 1 family Cas_GSU0054 PF09609.10 EPE24780.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) HSP70 PF00012.20 EPE24781.1 - 0.0044 15.3 0.2 0.015 13.5 0.1 1.9 2 1 0 2 2 2 1 Hsp70 protein GTP_CH_N PF12471.8 EPE24781.1 - 0.13 12.0 0.0 1 9.1 0.1 2.2 2 0 0 2 2 2 0 GTP cyclohydrolase N terminal zf-MYND PF01753.18 EPE24783.1 - 5.4e-09 36.0 12.0 1e-08 35.1 12.0 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EPE24783.1 - 0.00069 19.9 8.0 0.0013 19.0 8.0 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding DUF4303 PF14136.6 EPE24783.1 - 0.13 12.0 0.3 0.2 11.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) PLATZ PF04640.14 EPE24783.1 - 0.27 11.9 4.2 0.69 10.6 4.2 1.6 1 0 0 1 1 1 0 PLATZ transcription factor zf-HIT PF04438.16 EPE24783.1 - 0.27 11.1 8.6 0.59 10.1 8.6 1.5 1 0 0 1 1 1 0 HIT zinc finger DZR PF12773.7 EPE24783.1 - 1.1 9.4 7.4 2.8 8.0 7.4 1.7 1 0 0 1 1 1 0 Double zinc ribbon Ribonuclease_3 PF00636.26 EPE24784.1 - 1.6e-08 35.1 0.0 3.5e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EPE24784.1 - 5.3e-08 33.1 0.0 6.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like TPR_10 PF13374.6 EPE24786.1 - 1.5e-47 158.2 7.3 1.4e-13 50.2 0.2 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EPE24786.1 - 6.3e-46 154.6 14.0 2.2e-13 50.3 0.7 3.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 EPE24786.1 - 3.5e-15 54.8 3.3 0.00096 19.0 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EPE24786.1 - 3.5e-13 48.8 4.4 0.0086 15.9 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EPE24786.1 - 2.2e-12 47.4 0.2 0.033 14.8 0.0 4.1 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EPE24786.1 - 1.4e-11 43.6 2.7 0.009 16.1 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EPE24786.1 - 2.7e-11 43.0 4.1 0.04 14.3 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 EPE24786.1 - 1.8e-09 37.3 0.3 0.12 13.1 0.1 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPE24786.1 - 1.6e-08 34.1 5.3 0.11 12.8 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPE24786.1 - 5.2e-08 33.3 1.3 0.043 14.3 0.1 3.6 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_3 PF07720.12 EPE24786.1 - 3.1e-05 23.8 2.3 0.012 15.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE24786.1 - 9.1e-05 22.6 1.7 2.9 8.2 0.0 3.9 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EPE24786.1 - 0.0015 18.0 1.9 0.0018 17.7 1.9 1.2 1 0 0 1 1 1 1 MalT-like TPR region Gly_radical PF01228.21 EPE24786.1 - 0.0015 19.0 0.2 0.57 10.7 0.0 2.9 1 1 2 3 3 3 1 Glycine radical PPR PF01535.20 EPE24786.1 - 0.0021 18.2 0.1 6 7.4 0.0 3.8 4 0 0 4 4 4 1 PPR repeat DUF4404 PF14357.6 EPE24786.1 - 0.0057 17.3 2.4 6.7 7.4 0.1 3.0 1 1 2 3 3 3 1 Domain of unknown function (DUF4404) TPR_20 PF14561.6 EPE24786.1 - 0.0074 16.6 4.5 7.7 6.9 0.0 4.3 3 2 1 4 4 4 1 Tetratricopeptide repeat Ribophorin_II PF05817.14 EPE24786.1 - 0.012 14.2 0.1 0.068 11.7 0.0 1.7 1 1 1 2 2 2 0 Oligosaccharyltransferase subunit Ribophorin II TPR_14 PF13428.6 EPE24786.1 - 0.022 15.5 5.0 3.8 8.6 0.4 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat DED PF01335.21 EPE24786.1 - 0.035 14.4 1.2 24 5.3 0.1 3.2 2 1 1 3 3 3 0 Death effector domain Gln_amidase PF15644.6 EPE24786.1 - 0.048 14.7 0.1 14 6.8 0.1 2.5 1 1 2 3 3 3 0 Papain fold toxin 1, glutamine deamidase TPR_6 PF13174.6 EPE24786.1 - 0.16 12.7 2.8 2.8 8.8 0.0 3.6 4 0 0 4 4 2 0 Tetratricopeptide repeat Patatin PF01734.22 EPE24787.1 - 1.6e-22 80.7 0.0 5e-22 79.1 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase NB-ARC PF00931.22 EPE24787.1 - 5.6e-09 35.6 0.0 8.5e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 EPE24787.1 - 1.2e-06 28.5 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EPE24787.1 - 5.7e-06 26.8 0.0 1.8e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPE24787.1 - 7.6e-06 26.2 0.0 1.7e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain TPR_10 PF13374.6 EPE24787.1 - 0.0013 18.5 0.0 0.013 15.4 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TniB PF05621.11 EPE24787.1 - 0.0067 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein TPR_12 PF13424.6 EPE24787.1 - 0.15 12.4 0.1 2 8.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Phage_Treg PF04761.12 EPE24787.1 - 0.19 11.8 0.2 0.38 10.9 0.2 1.4 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator p450 PF00067.22 EPE24789.1 - 2.4e-45 155.1 0.0 3e-45 154.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 2OG-FeII_Oxy_3 PF13640.6 EPE24790.1 - 3.2e-08 34.4 0.0 5.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Asp PF00026.23 EPE24792.1 - 1e-13 51.4 0.0 1.5e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease AbrB PF05145.12 EPE24792.1 - 0.22 10.4 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Transition state regulatory protein AbrB DUF2001 PF09393.10 EPE24793.1 - 0.39 10.7 6.2 0.29 11.1 4.4 1.8 1 1 0 1 1 1 0 Phage tail tube protein Acetyltransf_7 PF13508.7 EPE24794.1 - 0.00038 20.8 0.0 0.00076 19.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE24794.1 - 0.0024 18.1 0.0 0.0067 16.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE24794.1 - 0.0067 16.4 0.1 0.015 15.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF1899 PF08953.11 EPE24795.1 - 1.9e-34 117.3 0.1 3.4e-34 116.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EPE24795.1 - 1.3e-19 69.8 0.1 2.9e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EPE24795.1 - 4.4e-17 62.1 7.1 0.00023 21.9 0.2 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE24795.1 - 1.1e-06 28.8 0.0 0.027 14.8 0.1 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPE24795.1 - 0.0033 16.1 0.1 1.5 7.4 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 MFS_1 PF07690.16 EPE24797.1 - 4.8e-35 121.1 22.0 1.1e-32 113.4 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GMC_oxred_N PF00732.19 EPE24797.1 - 3.1e-32 112.1 0.0 3.7e-25 88.9 0.0 2.8 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE24797.1 - 4.6e-30 105.0 0.0 8.4e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase MFS_4 PF06779.14 EPE24797.1 - 6.2e-09 35.6 3.9 6.2e-09 35.6 3.9 2.6 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DAO PF01266.24 EPE24797.1 - 9e-06 25.5 0.0 2.4e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPE24797.1 - 0.014 14.7 0.0 0.85 8.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1248 PF06852.12 EPE24797.1 - 0.018 14.5 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1248) Lycopene_cycl PF05834.12 EPE24797.1 - 0.029 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPE24797.1 - 0.055 13.7 0.1 0.26 11.5 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain APH PF01636.23 EPE24799.1 - 6.7e-15 55.7 0.0 9.1e-14 52.0 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EPE24799.1 - 0.00065 18.7 0.0 0.14 11.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.20 EPE24799.1 - 0.0095 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Acetyltransf_3 PF13302.7 EPE24801.1 - 2.2e-15 57.5 0.0 3.3e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE24801.1 - 2.1e-06 28.0 0.0 2.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family NAP PF00956.18 EPE24802.1 - 1.9e-27 96.2 0.2 5.2e-24 84.8 0.0 2.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Asparaginase PF00710.20 EPE24803.1 - 1.2e-58 197.8 0.0 2e-58 197.1 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EPE24803.1 - 1.3e-23 83.3 0.0 3e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 EPE24803.1 - 1.2e-09 38.6 0.1 3.8e-05 24.2 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE24803.1 - 1.4e-09 38.3 0.3 1.3e-08 35.2 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EPE24803.1 - 4.2e-07 30.1 0.1 0.00019 21.7 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EPE24803.1 - 2.3e-06 27.5 0.0 0.05 14.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EPE24803.1 - 1.9e-05 24.9 0.3 0.00047 20.4 0.3 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) CBP_BcsR PF10945.8 EPE24803.1 - 0.092 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR PTR2 PF00854.21 EPE24804.1 - 4.5e-81 272.7 8.8 6.5e-81 272.2 8.8 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EPE24804.1 - 6.4e-13 48.3 19.8 9.3e-13 47.8 17.5 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Beta-lactamase PF00144.24 EPE24805.1 - 1.9e-50 172.0 0.0 2.5e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EPE24805.1 - 4.7e-16 59.1 0.0 8.4e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Peptidase_S11 PF00768.20 EPE24805.1 - 0.0099 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase p450 PF00067.22 EPE24806.1 - 2.1e-49 168.5 0.0 2.7e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 EPE24807.1 - 5.3e-14 52.8 0.0 1e-13 51.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 EPE24808.1 - 2.9e-12 47.0 0.0 2.4e-06 28.0 0.0 3.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE24808.1 - 6.6e-12 45.7 0.1 8e-07 29.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE24808.1 - 1.4e-07 31.6 0.1 0.0019 18.5 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE24808.1 - 3e-07 30.2 1.1 0.00081 19.7 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EPE24808.1 - 1.7e-06 28.2 0.1 0.014 15.8 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat SesA PF17107.5 EPE24808.1 - 2.3e-06 27.8 0.8 4.5e-06 26.9 0.8 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 EPE24808.1 - 3.8e-05 23.2 2.7 5.7e-05 22.6 2.7 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DZF PF07528.14 EPE24808.1 - 0.024 14.2 0.3 0.054 13.1 0.0 1.7 2 0 0 2 2 2 0 DZF domain UPF0029 PF01205.19 EPE24809.1 - 5.3e-35 119.9 0.0 8.5e-35 119.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EPE24809.1 - 2.2e-07 31.2 0.0 2.8e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 RWD domain UQ_con PF00179.26 EPE24809.1 - 0.079 12.6 0.1 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-conjugating enzyme Kri1 PF05178.12 EPE24811.1 - 0.4 11.3 1.6 0.58 10.8 1.6 1.3 1 0 0 1 1 1 0 KRI1-like family GGACT PF06094.12 EPE24812.1 - 7.3e-13 49.2 0.0 1.2e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like VirionAssem_T7 PF11653.8 EPE24812.1 - 0.011 16.3 0.6 0.018 15.5 0.6 1.3 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein LPMO_10 PF03067.15 EPE24813.1 - 0.0036 18.0 0.0 0.0074 17.0 0.0 1.5 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading FMO-like PF00743.19 EPE24814.1 - 4.1e-21 75.0 0.5 6.2e-20 71.1 0.5 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EPE24814.1 - 5.2e-13 48.9 1.5 8.9e-11 41.6 0.2 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPE24814.1 - 4.8e-11 42.4 0.0 2.3e-08 33.7 0.0 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPE24814.1 - 1.7e-10 40.6 0.5 3.4e-08 33.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EPE24814.1 - 1.8e-09 37.7 0.0 5.2e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE24814.1 - 2.4e-07 30.7 0.4 3.9e-06 26.7 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPE24814.1 - 3.7e-06 26.3 0.1 5.6e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EPE24814.1 - 0.00034 20.0 0.0 0.0011 18.4 0.0 1.7 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EPE24814.1 - 0.00078 18.9 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EPE24814.1 - 0.00091 19.3 0.0 0.2 11.7 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 EPE24814.1 - 0.001 18.4 0.1 0.0022 17.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EPE24814.1 - 0.0051 16.1 0.2 0.078 12.2 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EPE24814.1 - 0.0071 15.1 0.7 0.036 12.8 0.7 2.1 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_9 PF13454.6 EPE24814.1 - 0.014 15.3 0.0 0.048 13.7 0.0 2.0 2 0 0 2 2 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EPE24814.1 - 0.035 13.2 0.1 0.08 12.0 0.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein MCRA PF06100.11 EPE24814.1 - 0.04 12.7 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 MCRA family AMP-binding PF00501.28 EPE24815.1 - 9.3e-39 133.2 0.0 1.4e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EPE24815.1 - 3.4e-07 30.1 0.2 7.9e-07 28.9 0.2 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF1757 PF08560.10 EPE24816.1 - 1.8e-05 24.9 0.1 3.6e-05 23.9 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1757) TPR_2 PF07719.17 EPE24817.1 - 6.4e-31 104.0 10.4 0.00054 19.9 0.3 10.5 11 0 0 11 11 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE24817.1 - 8.8e-28 96.4 14.2 1.4e-23 82.9 0.6 5.0 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EPE24817.1 - 1.1e-27 94.7 1.0 7.9e-05 22.3 0.5 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 EPE24817.1 - 2.3e-23 82.3 10.4 9.7e-13 48.2 0.1 8.2 7 2 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EPE24817.1 - 2e-22 79.5 7.8 0.0015 19.0 0.0 7.6 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 EPE24817.1 - 6.3e-19 66.6 0.4 0.0021 18.1 0.1 8.9 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 EPE24817.1 - 2.5e-16 59.0 5.3 0.29 12.0 0.0 9.0 5 3 4 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 EPE24817.1 - 3.6e-13 48.5 8.4 0.041 13.9 0.0 7.6 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EPE24817.1 - 2.3e-12 47.4 8.3 0.00067 20.2 0.1 7.8 6 3 1 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 EPE24817.1 - 4.2e-10 39.2 3.4 0.027 14.3 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 EPE24817.1 - 4.8e-09 35.8 5.5 2.5 7.9 0.0 7.1 7 2 2 9 9 9 3 TPR repeat TPR_6 PF13174.6 EPE24817.1 - 4.3e-08 33.3 9.4 0.29 11.9 0.2 7.6 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 EPE24817.1 - 0.00032 20.8 3.4 9.4 6.5 0.0 5.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EPE24817.1 - 0.0019 18.4 1.1 73 4.1 0.0 7.1 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_21 PF09976.9 EPE24817.1 - 0.0024 17.6 0.7 8.1 6.1 0.1 4.2 3 2 1 4 4 4 1 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 EPE24817.1 - 0.0057 16.1 2.4 0.24 10.7 0.0 3.8 3 1 0 4 4 4 1 MalT-like TPR region TPR_15 PF13429.6 EPE24817.1 - 0.0065 15.7 1.9 2.7 7.2 0.1 4.2 3 3 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 EPE24817.1 - 0.01 16.3 0.3 28 5.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EPE24817.1 - 0.013 15.5 1.2 0.9 9.6 0.1 3.9 4 1 0 4 4 4 0 Putative TPR-like repeat TPR_5 PF12688.7 EPE24817.1 - 0.064 13.5 0.1 0.37 11.0 0.0 2.4 2 0 0 2 2 1 0 Tetratrico peptide repeat RPN7 PF10602.9 EPE24817.1 - 0.078 12.7 6.6 9.3 5.9 0.0 4.9 5 2 0 5 5 5 0 26S proteasome subunit RPN7 DUF572 PF04502.13 EPE24818.1 - 8.4e-71 239.3 18.0 9.9e-71 239.1 18.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 EPE24818.1 - 0.47 10.6 3.7 1.4 9.0 0.8 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain RNA_pol_N PF01194.17 EPE24818.1 - 1.6 9.1 4.7 37 4.7 0.1 3.0 2 1 0 2 2 2 0 RNA polymerases N / 8 kDa subunit Transglut_i_TM PF14400.6 EPE24818.1 - 1.9 8.5 7.1 4.2 7.4 0.6 2.2 1 1 1 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices XAP5 PF04921.14 EPE24818.1 - 1.9 8.2 10.9 3.1 7.6 10.9 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator zf-C2H2_4 PF13894.6 EPE24819.1 - 4.9e-18 64.3 24.5 0.0075 17.0 0.4 6.3 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2 PF00096.26 EPE24819.1 - 6.7e-17 60.9 32.2 0.00081 19.7 1.1 6.3 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EPE24819.1 - 3.1e-15 56.0 24.5 1.8e-05 24.9 2.0 5.3 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EPE24819.1 - 2e-10 40.6 20.5 0.019 15.4 0.1 6.4 6 0 0 6 6 6 3 Zinc-finger double domain zf-met PF12874.7 EPE24819.1 - 9e-09 35.4 26.4 3.3e-05 24.1 2.9 4.8 5 0 0 5 5 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EPE24819.1 - 8.2e-08 32.1 24.0 0.013 15.5 0.7 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EPE24819.1 - 1.8e-05 25.0 25.3 0.022 15.1 1.8 5.3 1 1 4 5 5 5 2 C2H2 type zinc-finger (2 copies) DUF1360 PF07098.11 EPE24819.1 - 0.021 14.7 0.1 0.074 13.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) DUF1272 PF06906.11 EPE24819.1 - 0.028 14.5 1.2 0.028 14.5 1.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1272) Rad50_zn_hook PF04423.14 EPE24819.1 - 0.12 12.3 0.0 0.12 12.3 0.0 4.1 5 0 0 5 5 5 0 Rad50 zinc hook motif Prok-RING_4 PF14447.6 EPE24819.1 - 0.18 11.7 7.3 60 3.6 6.8 3.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C2H2_9 PF16293.5 EPE24819.1 - 0.19 11.6 9.8 15 5.5 0.2 4.5 5 0 0 5 5 5 0 C2H2 type zinc-finger (1 copy) Anti-TRAP PF15777.5 EPE24819.1 - 0.2 11.6 2.8 1.9 8.5 0.2 2.8 3 0 0 3 3 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 EPE24819.1 - 0.22 11.5 16.1 11 6.0 6.7 4.3 2 2 1 3 3 3 0 zinc-ribbons zf-Di19 PF05605.12 EPE24819.1 - 0.24 11.7 0.0 0.24 11.7 0.0 4.9 3 1 3 6 6 6 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 EPE24819.1 - 0.29 11.3 26.8 4.9 7.3 0.5 5.3 3 2 2 5 5 5 0 Zinc ribbon domain Spt46 PF17734.1 EPE24819.1 - 0.5 10.1 6.2 2 8.2 0.2 3.0 1 1 2 3 3 3 0 Spermatogenesis-associated protein 46 zf-C2H2_aberr PF17017.5 EPE24819.1 - 0.52 10.4 0.1 0.52 10.4 0.1 3.0 3 1 0 3 3 3 0 Aberrant zinc-finger zf_ZIC PF18366.1 EPE24819.1 - 0.94 9.6 15.4 3.9 7.7 0.0 4.4 5 0 0 5 5 5 0 Zic proteins zinc finger domain zf_Hakai PF18408.1 EPE24819.1 - 1.5 8.6 8.9 0.98 9.2 2.9 2.9 3 0 0 3 3 2 0 C2H2 Hakai zinc finger domain zf-RVT PF13966.6 EPE24819.1 - 2.6 8.8 5.1 15 6.3 0.1 3.3 3 1 0 3 3 3 0 zinc-binding in reverse transcriptase zf-RING_2 PF13639.6 EPE24819.1 - 6.6 7.2 13.6 2.1 8.7 7.1 3.3 3 1 0 3 3 3 0 Ring finger domain zf-C2HC_2 PF13913.6 EPE24819.1 - 8.5 6.4 24.3 3.1 7.8 0.1 5.7 6 0 0 6 6 5 0 zinc-finger of a C2HC-type F-box-like PF12937.7 EPE24820.1 - 4.7e-05 23.2 1.1 0.00023 21.0 0.1 2.6 3 0 0 3 3 3 1 F-box-like F-box-like_2 PF13013.6 EPE24820.1 - 0.049 13.6 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain Lipase_GDSL_2 PF13472.6 EPE24821.1 - 1.1e-16 61.8 0.3 1.5e-16 61.3 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE24821.1 - 1.6e-11 44.6 0.1 2e-11 44.2 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 EPE24821.1 - 0.006 15.8 0.0 0.0075 15.5 0.0 1.1 1 0 0 1 1 1 1 OSK domain Lipase_GDSL PF00657.22 EPE24822.1 - 2.9e-08 33.9 0.0 4.2e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EPE24822.1 - 3.5e-05 24.3 1.8 4.9e-05 23.8 1.8 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Abhydrolase_2 PF02230.16 EPE24823.1 - 3.6e-09 36.8 0.2 2.2e-06 27.7 0.1 2.4 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EPE24823.1 - 0.058 12.9 0.2 0.13 11.7 0.2 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 EPE24823.1 - 0.08 12.4 0.6 0.52 9.8 0.3 2.3 1 1 0 1 1 1 0 Esterase PHB depolymerase GHMP_kinases_N PF00288.26 EPE24823.1 - 3.5 7.9 6.1 14 6.0 0.3 2.9 3 0 0 3 3 3 0 GHMP kinases N terminal domain MIP PF00230.20 EPE24824.1 - 1e-26 94.1 9.0 1.8e-26 93.2 9.0 1.4 1 1 0 1 1 1 1 Major intrinsic protein Fungal_trans PF04082.18 EPE24825.1 - 2.9e-16 59.3 0.2 8.1e-16 57.8 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1788 PF08747.11 EPE24825.1 - 0.076 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) DUF3382 PF11862.8 EPE24827.1 - 0.0063 16.8 2.1 0.015 15.6 0.9 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3382) MHC_I_3 PF16497.5 EPE24827.1 - 0.073 12.6 0.2 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 MHC-I family domain Aminotran_5 PF00266.19 EPE24829.1 - 7.4e-11 41.6 0.0 2.1e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EPE24829.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family IDO PF01231.18 EPE24830.1 - 7.7e-148 492.9 0.0 9e-148 492.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Methyltransf_33 PF10017.9 EPE24831.1 - 0.051 12.7 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent COX7B PF05392.11 EPE24831.1 - 0.065 12.9 0.0 0.42 10.3 0.0 2.4 1 1 1 2 2 2 0 Cytochrome C oxidase chain VIIB RXLR PF16810.5 EPE24831.1 - 0.17 12.4 0.0 0.3 11.5 0.0 1.5 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity WD40 PF00400.32 EPE24832.1 - 1.3e-28 98.6 7.6 1.5e-05 25.6 0.2 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 EPE24832.1 - 8.7e-08 31.3 4.6 0.00049 18.9 0.0 4.1 2 1 2 4 4 4 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EPE24832.1 - 1.1e-07 32.1 0.1 3.9 7.8 0.0 5.4 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EPE24832.1 - 4.7e-05 22.9 0.0 0.38 10.0 0.0 2.8 1 1 0 2 2 2 2 WD40-like domain BBS2_Mid PF14783.6 EPE24832.1 - 0.0068 16.4 0.0 0.14 12.2 0.0 2.8 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 EPE24832.1 - 0.091 13.3 1.3 1.6 9.3 0.1 3.5 3 1 1 4 4 4 0 PQQ-like domain Peptidase_S9_N PF02897.15 EPE24832.1 - 0.14 10.9 0.0 15 4.3 0.0 2.7 2 1 1 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Hira PF07569.11 EPE24832.1 - 0.15 11.7 0.1 23 4.6 0.0 2.6 3 0 0 3 3 3 0 TUP1-like enhancer of split YihI PF04220.12 EPE24833.1 - 0.16 11.6 2.9 0.21 11.3 2.9 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) Macoilin PF09726.9 EPE24833.1 - 1.5 7.3 4.9 1.7 7.1 4.9 1.0 1 0 0 1 1 1 0 Macoilin family SDA1 PF05285.12 EPE24834.1 - 0.047 13.1 27.3 0.089 12.2 27.3 1.4 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.11 EPE24834.1 - 3.4 7.3 15.9 4.9 6.8 15.9 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) NmrA PF05368.13 EPE24838.1 - 2.1e-66 223.8 0.0 2.6e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE24838.1 - 0.0022 17.9 0.1 0.029 14.3 0.1 2.1 1 1 0 1 1 1 1 NAD(P)H-binding FAT PF02259.23 EPE24839.1 - 5.6e-74 249.4 4.3 1.4e-73 248.1 4.3 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EPE24839.1 - 7.9e-33 114.3 0.4 1.8e-32 113.1 0.4 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EPE24839.1 - 7.9e-06 25.6 0.0 2e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 FATC domain FANCI_S2 PF14676.6 EPE24839.1 - 0.006 16.9 3.0 3.4 7.9 0.0 5.2 6 0 0 6 6 6 1 FANCI solenoid 2 TPR_1 PF00515.28 EPE24839.1 - 0.0084 15.9 2.8 0.7 9.8 0.2 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPE24839.1 - 0.025 14.7 3.6 3.8 7.9 0.4 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EPE24839.1 - 0.87 10.0 3.2 1.5 9.2 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1772 PF08592.11 EPE24840.1 - 6.5e-26 91.3 0.0 9.2e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) RNF220 PF15926.5 EPE24842.1 - 0.028 14.1 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 Amnionless PF14828.6 EPE24843.1 - 0.17 10.7 0.1 0.2 10.5 0.1 1.1 1 0 0 1 1 1 0 Amnionless MGC-24 PF05283.11 EPE24843.1 - 0.71 10.3 9.8 1.3 9.4 9.1 1.8 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin CAP59_mtransfer PF11735.8 EPE24844.1 - 6.7e-66 222.4 0.0 8.9e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 NAS PF03059.16 EPE24845.1 - 6.7e-62 209.3 0.1 9.1e-62 208.9 0.1 1.0 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.6 EPE24845.1 - 4.4e-07 29.8 0.0 7.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Tma16 PF11176.8 EPE24846.1 - 0.12 12.3 0.1 0.31 10.9 0.1 1.7 1 0 0 1 1 1 0 Translation machinery-associated protein 16 LOH1CR12 PF10158.9 EPE24846.1 - 0.14 12.2 0.3 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 Tumour suppressor protein Sugar_tr PF00083.24 EPE24847.1 - 3.7e-42 144.7 20.8 6e-23 81.4 8.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EPE24847.1 - 6.7e-22 77.9 29.6 2.2e-14 53.2 19.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 EPE24848.1 - 1.5e-15 56.9 0.1 2.3e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 EPE24849.1 - 9.8e-21 74.1 0.1 5.1e-15 55.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE24849.1 - 2.2e-16 60.2 0.0 1.6e-10 41.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE24849.1 - 3.5e-06 27.1 0.3 6.3e-06 26.2 0.3 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE24849.1 - 0.024 14.1 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family BCS1_N PF08740.11 EPE24851.1 - 5.6e-44 150.4 0.0 9.5e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EPE24851.1 - 1.3e-15 58.0 0.0 2.8e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EPE24851.1 - 0.0019 17.9 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EPE24851.1 - 0.015 14.9 0.0 0.053 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EPE24851.1 - 0.016 15.2 0.0 0.23 11.5 0.1 2.9 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 EPE24851.1 - 0.017 14.4 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 EPE24851.1 - 0.029 14.9 0.0 0.077 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EPE24851.1 - 0.047 14.1 0.1 0.099 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Syntaxin-6_N PF09177.11 EPE24852.1 - 1.9e-24 86.1 0.5 1.9e-24 86.1 0.5 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal DUF1664 PF07889.12 EPE24852.1 - 0.0036 17.3 0.6 1.9 8.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) LPP PF04728.13 EPE24852.1 - 0.046 14.1 1.5 0.5 10.8 1.3 2.5 1 1 1 2 2 2 0 Lipoprotein leucine-zipper WXG100 PF06013.12 EPE24852.1 - 0.069 13.4 3.1 5 7.4 0.0 3.5 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF4407 PF14362.6 EPE24852.1 - 0.1 12.0 0.3 0.14 11.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 EPE24852.1 - 0.2 12.0 3.2 3.1 8.1 0.5 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Methyltransf_32 PF13679.6 EPE24853.1 - 7.4e-20 71.5 0.1 2.6e-19 69.8 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Sof1 PF04158.14 EPE24853.1 - 0.089 13.1 1.1 0.28 11.5 1.1 1.8 1 0 0 1 1 1 0 Sof1-like domain Pentapeptide_4 PF13599.6 EPE24855.1 - 1.6e-08 34.6 6.3 0.00086 19.4 1.5 4.2 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EPE24855.1 - 0.077 13.2 0.4 7.8 6.7 0.0 3.8 5 0 0 5 5 5 0 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 EPE24856.1 - 1.1e-07 31.9 2.5 0.04 14.1 2.7 4.2 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EPE24856.1 - 0.016 15.3 1.1 6.6 7.0 0.0 3.6 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) Acetyltransf_1 PF00583.25 EPE24857.1 - 1.9e-07 31.3 0.0 2.3e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE24857.1 - 0.00018 21.9 0.0 0.00024 21.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPE24857.1 - 0.00056 19.9 0.0 0.00076 19.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE24857.1 - 0.032 14.2 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein FAD_binding_4 PF01565.23 EPE24859.1 - 9.6e-20 70.7 0.6 2e-19 69.7 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE24859.1 - 7.7e-12 45.1 0.1 1.6e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_A4 PF01828.17 EPE24860.1 - 3e-27 95.5 0.9 5e-27 94.7 0.9 1.3 1 0 0 1 1 1 1 Peptidase A4 family Lipocalin_2 PF08212.12 EPE24860.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipocalin-like domain WD40 PF00400.32 EPE24862.1 - 1.2e-18 67.1 16.4 0.0004 21.1 0.1 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE24862.1 - 2.1e-06 28.0 0.7 0.22 11.8 0.0 4.5 3 3 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 EPE24862.1 - 0.093 12.7 1.1 39 4.4 0.0 3.7 3 0 0 3 3 3 0 PQQ enzyme repeat Fungal_trans PF04082.18 EPE24863.1 - 5.8e-26 91.1 1.5 9e-26 90.5 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE24863.1 - 8e-07 29.1 8.6 8e-07 29.1 8.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MMR_HSR1 PF01926.23 EPE24866.1 - 1.2e-09 38.3 0.1 1.6e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPE24866.1 - 1.5e-05 25.0 0.1 3.4e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EPE24866.1 - 0.00037 20.6 0.6 0.35 10.9 0.0 2.3 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 EPE24866.1 - 0.00099 18.7 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 EPE24866.1 - 0.0011 18.4 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.6 EPE24866.1 - 0.0017 18.6 0.0 0.0025 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPE24866.1 - 0.0017 18.8 0.0 0.0024 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EPE24866.1 - 0.0065 17.0 0.0 0.0093 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain IIGP PF05049.13 EPE24866.1 - 0.0085 15.2 0.1 0.016 14.3 0.1 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 EPE24866.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EPE24866.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EPE24867.1 - 2.1e-10 40.7 0.0 4.6e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EPE24867.1 - 0.00054 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 EPE24867.1 - 0.0014 18.6 0.3 0.0025 17.8 0.3 1.5 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EPE24867.1 - 0.0016 18.9 0.0 0.0032 18.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AIG1 PF04548.16 EPE24867.1 - 0.0021 17.4 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 EPE24867.1 - 0.0025 17.3 0.1 0.0048 16.3 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 EPE24867.1 - 0.0072 16.4 5.9 0.19 11.8 0.0 2.7 2 1 1 3 3 3 2 Dynamin family HlyD_D23 PF16576.5 EPE24867.1 - 0.23 10.6 0.9 0.39 9.9 0.9 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion GATase_5 PF13507.6 EPE24868.1 - 1.1e-99 332.7 0.0 1.8e-99 332.1 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EPE24868.1 - 2.3e-37 128.5 0.1 2.2e-24 86.3 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EPE24868.1 - 1e-24 86.7 0.0 2.1e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EPE24868.1 - 2.6e-21 75.9 0.2 7.7e-21 74.4 0.2 1.9 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Imm64 PF15600.6 EPE24868.1 - 0.096 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 64 PQ-loop PF04193.14 EPE24869.1 - 3.2e-14 52.4 0.9 8e-14 51.2 0.9 1.7 1 0 0 1 1 1 1 PQ loop repeat ORC6 PF05460.13 EPE24869.1 - 0.57 9.4 7.3 0.89 8.8 7.3 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) HATPase_c PF02518.26 EPE24872.1 - 5.3e-24 84.9 0.2 1.2e-23 83.7 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPE24872.1 - 1.5e-18 67.0 2.2 3.8e-13 49.6 0.0 3.6 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 EPE24872.1 - 4.2e-09 36.3 2.8 7.1e-09 35.6 0.3 2.8 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EPE24872.1 - 0.03 14.6 0.0 3 8.1 0.0 3.4 3 0 0 3 3 3 0 PAS domain DUF1828 PF08861.10 EPE24872.1 - 0.071 13.4 0.0 0.29 11.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function DUF1828 PAS_4 PF08448.10 EPE24872.1 - 0.082 13.2 0.0 12 6.2 0.0 3.0 2 1 0 2 2 2 0 PAS fold B56 PF01603.20 EPE24873.1 - 3.1e-192 639.1 6.4 3.7e-192 638.9 6.4 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 EPE24873.1 - 0.00077 19.4 2.1 0.32 10.9 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Tau95_N PF17682.1 EPE24874.1 - 2.5e-41 140.8 0.0 4.5e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 Tau95 Triple barrel domain Tau95 PF09734.9 EPE24874.1 - 3e-35 122.1 1.7 5.1e-35 121.3 1.7 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Ifi-6-16 PF06140.13 EPE24875.1 - 0.0045 16.9 0.5 0.013 15.4 0.5 1.8 1 0 0 1 1 1 1 Interferon-induced 6-16 family HET PF06985.11 EPE24876.1 - 1.7e-28 99.8 0.0 2.6e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.19 EPE24878.1 - 5.8e-23 81.7 0.0 4.4e-22 78.8 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EPE24878.1 - 3.1e-06 27.3 0.7 7.8e-06 26.0 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE24878.1 - 1.2e-05 24.7 1.0 0.031 13.5 0.7 2.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE24878.1 - 0.00021 20.5 3.4 0.014 14.5 4.3 2.2 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.24 EPE24878.1 - 0.0011 18.6 1.6 0.048 13.2 2.2 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EPE24878.1 - 0.0013 17.7 0.1 0.0019 17.1 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EPE24878.1 - 0.0072 15.6 0.5 0.88 8.8 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EPE24878.1 - 0.028 13.5 0.0 0.12 11.4 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.17 EPE24878.1 - 0.042 13.1 0.7 0.083 12.1 0.3 1.6 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 EPE24878.1 - 0.049 13.0 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.21 EPE24878.1 - 0.17 11.2 0.1 0.31 10.3 0.1 1.4 1 0 0 1 1 1 0 ThiF family GIDA PF01134.22 EPE24878.1 - 0.28 10.2 1.6 0.43 9.6 1.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A GCP_N_terminal PF17681.1 EPE24879.1 - 5.9e-38 131.2 0.2 2.3e-37 129.3 0.3 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EPE24879.1 - 8.8e-32 110.8 1.4 2e-31 109.6 1.4 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 EPE24879.1 - 4.8e-07 28.5 0.6 7.8e-06 24.5 0.6 2.1 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Glyco_transf_15 PF01793.16 EPE24880.1 - 1.1e-108 363.4 6.0 1.2e-108 363.2 6.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Beta-lactamase PF00144.24 EPE24881.1 - 6.9e-36 124.1 0.0 1e-35 123.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase MTHFR PF02219.17 EPE24882.1 - 1.8e-104 349.1 0.0 2.8e-104 348.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Aminotran_1_2 PF00155.21 EPE24883.1 - 9e-08 31.7 0.0 8.1e-07 28.5 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II DLH PF01738.18 EPE24884.1 - 1.4e-17 64.0 0.0 3.5e-17 62.7 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EPE24884.1 - 0.087 12.7 0.0 1.2 9.0 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Atg14 PF10186.9 EPE24886.1 - 0.053 12.6 1.7 0.054 12.6 1.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MIP PF00230.20 EPE24887.1 - 4e-39 134.6 18.7 5.2e-39 134.3 18.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Peptidase_U4 PF03419.13 EPE24887.1 - 1.3 8.3 12.0 2.3 7.4 12.0 1.6 1 1 0 1 1 1 0 Sporulation factor SpoIIGA UPF0444 PF15475.6 EPE24887.1 - 9.1 6.6 7.3 1.2 9.5 2.4 2.1 3 0 0 3 3 3 0 Transmembrane protein C12orf23, UPF0444 adh_short PF00106.25 EPE24888.1 - 2e-21 76.4 0.0 4.9e-20 71.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE24888.1 - 3.3e-10 39.9 0.0 5.9e-09 35.8 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE24888.1 - 0.00012 22.0 0.0 0.00016 21.6 0.0 1.3 1 1 0 1 1 1 1 KR domain Corona_NS2A PF05213.12 EPE24888.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NS2A protein Pkinase PF00069.25 EPE24889.1 - 6e-18 65.2 0.0 9.3e-16 58.0 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE24889.1 - 1.1e-09 37.9 0.0 6.6e-09 35.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase wnt PF00110.19 EPE24890.1 - 0.0017 18.0 1.9 0.0043 16.7 1.9 1.6 1 1 0 1 1 1 1 wnt family UPF0242 PF06785.11 EPE24890.1 - 0.31 11.1 7.0 0.53 10.4 7.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Pkinase PF00069.25 EPE24891.1 - 2.4e-20 73.0 0.0 9.8e-20 71.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE24891.1 - 1.6e-12 47.3 0.0 3.1e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HNH_2 PF13391.6 EPE24892.1 - 1.9e-09 37.5 0.0 4.9e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease YopX PF09643.10 EPE24892.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 YopX protein HSP20 PF00011.21 EPE24893.1 - 1.8e-20 73.0 0.2 1.7e-14 53.8 0.3 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EPE24893.1 - 9.4e-07 28.3 0.1 9.3e-06 25.1 0.1 2.1 1 1 0 1 1 1 1 HSP20-like domain found in ArsA RSN1_7TM PF02714.15 EPE24894.1 - 2.5e-79 266.5 21.7 6.9e-79 265.0 21.7 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EPE24894.1 - 1.2e-41 142.8 0.0 1.7e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EPE24894.1 - 1.6e-32 112.4 1.1 2.7e-32 111.7 0.0 2.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF1201 PF06716.11 EPE24894.1 - 0.056 13.5 0.2 0.056 13.5 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) DUF969 PF06149.12 EPE24894.1 - 0.077 12.4 0.3 0.46 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF969) ABC_tran_CTD PF16326.5 EPE24894.1 - 0.6 10.4 1.7 21 5.5 0.1 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain PKcGMP_CC PF16808.5 EPE24894.1 - 1.6 8.7 3.3 12 5.9 0.4 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PGM_PMM_I PF02878.16 EPE24895.1 - 4.9e-31 107.3 0.0 7.2e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EPE24895.1 - 3.4e-25 88.5 0.0 8.6e-25 87.2 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EPE24895.1 - 1.6e-15 57.5 0.0 3.5e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EPE24895.1 - 8.1e-09 35.5 0.0 1.8e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RNase_T PF00929.24 EPE24896.1 - 6.3e-25 88.6 0.1 7e-25 88.5 0.1 1.0 1 0 0 1 1 1 1 Exonuclease Lipoprotein_22 PF17294.2 EPE24896.1 - 0.08 12.6 0.1 0.62 9.7 0.0 2.0 1 1 0 2 2 2 0 Uncharacterised lipoprotein family ATP_sub_h PF10775.9 EPE24897.1 - 1.2e-28 98.9 0.9 1.6e-28 98.4 0.9 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h Lipase_GDSL_2 PF13472.6 EPE24898.1 - 4.7e-15 56.4 0.0 7.1e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE24898.1 - 1.3e-08 35.0 0.0 8.1e-08 32.5 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Corona_6B_7B PF03262.13 EPE24900.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Coronavirus 6B/7B protein zf-C3HC4_2 PF13923.6 EPE24900.1 - 2.4 8.1 16.6 1.4 8.8 7.9 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HET PF06985.11 EPE24901.1 - 5.5e-21 75.5 0.0 9.4e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MaoC_dehydratas PF01575.19 EPE24902.1 - 7.4e-21 74.0 0.0 1.3e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EPE24902.1 - 0.00016 21.8 0.0 0.0035 17.5 0.0 2.3 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase DUF1768 PF08719.11 EPE24903.1 - 5.9e-51 172.9 0.0 7.3e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF4357 PF14267.6 EPE24903.1 - 0.05 13.6 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4357) TFIIB PF00382.19 EPE24904.1 - 1.2e-35 121.4 0.1 2.1e-21 75.7 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EPE24904.1 - 7.9e-13 47.7 1.0 7.9e-13 47.7 1.0 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_C PF02984.19 EPE24904.1 - 2.9e-06 27.4 0.0 0.035 14.2 0.0 2.8 3 0 0 3 3 3 2 Cyclin, C-terminal domain RB_B PF01857.20 EPE24904.1 - 0.016 15.2 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Qn_am_d_aII PF14930.6 EPE24904.1 - 0.026 14.8 0.0 0.93 9.8 0.0 2.5 2 1 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II zf-ribbon_3 PF13248.6 EPE24904.1 - 0.026 13.9 0.6 0.09 12.2 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain AAA PF00004.29 EPE24905.1 - 4.7e-40 137.1 0.0 9.2e-40 136.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EPE24905.1 - 8e-19 67.3 0.1 1.6e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EPE24905.1 - 1.1e-07 31.5 0.0 2.3e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EPE24905.1 - 0.00016 21.7 0.1 0.00081 19.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPE24905.1 - 0.00021 21.7 1.7 0.021 15.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EPE24905.1 - 0.00031 20.5 0.0 0.00074 19.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EPE24905.1 - 0.0011 19.2 0.1 0.012 15.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 EPE24905.1 - 0.0059 16.1 0.2 0.081 12.4 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 EPE24905.1 - 0.0065 16.8 3.9 0.08 13.2 0.0 3.1 3 1 1 4 4 4 1 AAA domain Mg_chelatase PF01078.21 EPE24905.1 - 0.0081 15.6 0.1 0.02 14.3 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EPE24905.1 - 0.015 15.5 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EPE24905.1 - 0.017 14.3 0.0 0.035 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) JIP_LZII PF16471.5 EPE24905.1 - 0.079 13.1 0.9 0.29 11.3 0.9 2.0 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II IstB_IS21 PF01695.17 EPE24905.1 - 0.082 12.6 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EPE24905.1 - 0.13 11.7 0.0 0.35 10.4 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 EPE24905.1 - 0.6 9.8 0.0 0.6 9.8 0.0 2.8 2 1 0 3 3 2 0 AAA domain Pro-kuma_activ PF09286.11 EPE24906.1 - 1e-46 158.8 0.1 2.8e-45 154.1 0.0 2.7 2 1 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EPE24906.1 - 1.5e-05 24.5 0.3 2.4e-05 23.8 0.3 1.3 1 0 0 1 1 1 1 Subtilase family ADH_zinc_N PF00107.26 EPE24907.1 - 8.8e-13 48.4 0.0 2.5e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE24907.1 - 9.8e-09 35.1 0.0 1.2e-07 31.6 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EPE24907.1 - 0.13 13.3 0.0 0.24 12.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EPE24907.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase F-box-like PF12937.7 EPE24908.1 - 0.0002 21.2 0.1 0.00046 20.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE24908.1 - 0.015 15.1 0.3 0.031 14.2 0.3 1.4 1 0 0 1 1 1 0 F-box domain Phage_SSB PF16773.5 EPE24910.1 - 0.21 11.7 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 Lactococcus phage single-stranded DNA binding protein MFS_1 PF07690.16 EPE24912.1 - 5.9e-25 87.9 42.6 1.2e-23 83.6 42.6 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE24912.1 - 1.4e-20 73.3 14.7 1.8e-20 72.9 14.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RNase_T PF00929.24 EPE24913.1 - 6.8e-10 39.7 0.0 6.8e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 Exonuclease zf-C2H2 PF00096.26 EPE24913.1 - 0.015 15.7 0.4 0.045 14.2 0.4 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE24913.1 - 0.018 15.9 0.2 0.077 13.9 0.2 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE24913.1 - 0.02 15.2 0.9 0.051 13.9 0.9 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.12 EPE24913.1 - 0.54 11.0 7.3 1.6 9.5 4.9 2.4 1 1 1 2 2 2 0 CHORD Acyl_transf_3 PF01757.22 EPE24914.1 - 8.8e-32 110.5 36.0 1.1e-31 110.1 36.0 1.1 1 0 0 1 1 1 1 Acyltransferase family ABC2_membrane_2 PF12679.7 EPE24914.1 - 2 7.6 6.0 0.11 11.8 0.7 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein eIF3g PF12353.8 EPE24915.1 - 0.0003 21.2 38.8 0.00055 20.3 2.2 4.6 2 1 3 5 5 5 3 Eukaryotic translation initiation factor 3 subunit G Dicty_REP PF05086.12 EPE24915.1 - 8.3 4.2 11.4 11 3.8 11.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein p450 PF00067.22 EPE24916.1 - 1.6e-31 109.6 0.2 4.9e-30 104.7 0.2 2.3 1 1 0 1 1 1 1 Cytochrome P450 Acylphosphatase PF00708.18 EPE24917.1 - 1.8 9.0 3.7 15 6.1 0.3 3.1 2 1 1 3 3 3 0 Acylphosphatase F-box-like PF12937.7 EPE24918.1 - 7.3e-09 35.4 0.3 7.3e-09 35.4 0.3 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EPE24918.1 - 3e-05 23.8 4.3 0.027 14.3 0.5 4.1 4 0 0 4 4 4 2 F-box domain LRR_4 PF12799.7 EPE24918.1 - 0.68 10.4 7.3 26 5.4 0.1 4.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) DUF2175 PF09943.9 EPE24919.1 - 0.17 12.2 0.2 0.34 11.2 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Pox_Ag35 PF03286.14 EPE24921.1 - 0.049 13.4 0.1 0.068 13.0 0.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF508 PF04370.12 EPE24921.1 - 0.12 12.1 0.2 0.18 11.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) MFS_1 PF07690.16 EPE24922.1 - 6.1e-28 97.8 36.2 6.1e-28 97.8 36.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PLDc_N PF13396.6 EPE24923.1 - 6e-11 42.1 1.1 6e-11 42.1 1.1 1.5 2 0 0 2 2 2 1 Phospholipase_D-nuclease N-terminal FUSC-like PF12805.7 EPE24923.1 - 0.023 13.8 1.3 0.026 13.6 1.3 1.0 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF4199 PF13858.6 EPE24923.1 - 0.026 14.9 0.4 0.04 14.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF3951 PF13131.6 EPE24923.1 - 0.091 13.0 2.3 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) AMP-binding PF00501.28 EPE24924.1 - 2.2e-99 333.0 0.0 2.5e-99 332.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE24924.1 - 4.3e-14 53.3 1.4 2.3e-13 50.9 1.9 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain IBR PF01485.21 EPE24925.1 - 1.1e-13 51.2 29.4 1.1e-07 31.9 4.0 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-B_box PF00643.24 EPE24925.1 - 0.017 15.2 0.3 0.017 15.2 0.3 3.0 3 0 0 3 3 3 0 B-box zinc finger DUF4446 PF14584.6 EPE24925.1 - 2.5 8.1 7.8 3.3 7.7 1.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) DZR PF12773.7 EPE24926.1 - 0.00022 21.2 1.0 0.0025 17.8 0.1 2.6 2 1 0 2 2 2 1 Double zinc ribbon NOB1_Zn_bind PF08772.11 EPE24926.1 - 0.41 10.8 6.0 3.5 7.9 0.1 2.7 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Cytochrom_c3_2 PF14537.6 EPE24926.1 - 1.2 9.7 9.2 0.34 11.4 0.5 2.7 2 1 0 2 2 2 0 Cytochrome c3 Paired_CXXCH_1 PF09699.10 EPE24926.1 - 9.8 6.0 9.4 2.6 7.9 3.3 2.9 2 1 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Amidase PF01425.21 EPE24927.1 - 2.6e-33 115.7 2.1 1.4e-32 113.2 0.6 2.1 2 0 0 2 2 2 2 Amidase DFP PF04127.15 EPE24928.1 - 9.2e-13 48.4 0.0 2.8e-05 24.0 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein HAD PF12710.7 EPE24928.1 - 0.041 14.3 0.0 0.067 13.6 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.18 EPE24930.1 - 4.3e-23 81.7 0.2 6.9e-23 81.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE24930.1 - 1.6e-05 24.9 8.7 3.4e-05 23.9 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-O PF09496.10 EPE24931.1 - 1.1e-64 218.3 0.0 2.8e-64 217.0 0.0 1.6 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component SKA1 PF07160.12 EPE24931.1 - 0.065 13.1 0.2 0.099 12.5 0.2 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 FliJ PF02050.16 EPE24931.1 - 0.15 12.3 2.9 0.21 11.8 0.4 2.1 3 0 0 3 3 3 0 Flagellar FliJ protein Uds1 PF15456.6 EPE24931.1 - 0.59 10.3 2.8 0.27 11.4 0.5 1.6 2 0 0 2 2 2 0 Up-regulated During Septation Acatn PF13000.7 EPE24932.1 - 9.9e-166 552.4 20.0 1e-83 281.7 9.2 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 MFS_1_like PF12832.7 EPE24932.1 - 0.013 14.4 10.3 0.0045 15.9 7.5 1.5 1 1 0 1 1 1 0 MFS_1 like family BphX PF06139.12 EPE24932.1 - 0.25 11.3 6.5 0.32 10.9 0.1 2.9 3 0 0 3 3 3 0 BphX-like TFIIF_alpha PF05793.12 EPE24932.1 - 0.25 9.9 7.6 0.37 9.3 7.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YchF-GTPase_C PF06071.13 EPE24934.1 - 2.8e-33 113.9 0.1 7.8e-33 112.5 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EPE24934.1 - 1.2e-17 64.1 0.0 5.7e-17 61.9 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPE24934.1 - 0.0014 18.2 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 EPE24934.1 - 0.0053 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain BetaGal_dom3 PF13363.6 EPE24934.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 Dynamin_N PF00350.23 EPE24934.1 - 0.15 12.1 0.0 2.4 8.2 0.0 2.4 1 1 0 2 2 2 0 Dynamin family Peptidase_C97 PF05903.14 EPE24935.1 - 1.7e-34 118.9 0.0 2.2e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EPE24935.1 - 0.00043 20.6 0.0 0.00068 20.0 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.12 EPE24935.1 - 0.029 14.8 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Ribosomal_S11 PF00411.19 EPE24936.1 - 5.9e-12 46.0 0.0 1.6e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S11 Phage_Mu_Gam PF07352.12 EPE24936.1 - 0.2 11.6 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Tim44 PF04280.15 EPE24937.1 - 2.9e-35 121.5 0.0 6.1e-35 120.5 0.0 1.6 2 0 0 2 2 2 1 Tim44-like domain Med7 PF05983.11 EPE24937.1 - 0.073 13.2 4.7 0.14 12.2 4.7 1.4 1 0 0 1 1 1 0 MED7 protein Cdh1_DBD_1 PF18196.1 EPE24937.1 - 0.3 11.4 0.1 0.3 11.4 0.1 2.5 3 0 0 3 3 3 0 Chromodomain helicase DNA-binding domain 1 CDC45 PF02724.14 EPE24937.1 - 2.8 6.1 6.7 4.8 5.4 6.7 1.3 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EPE24937.1 - 6.8 4.7 6.7 15 3.5 6.7 1.5 2 0 0 2 2 2 0 DNA polymerase phi Polysacc_deac_1 PF01522.21 EPE24938.1 - 4.1e-18 65.5 0.0 8.7e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EPE24938.1 - 2.7e-05 23.9 0.0 4.3e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) VPS9 PF02204.18 EPE24939.1 - 2.2e-18 66.4 0.0 6.1e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 EPE24939.1 - 2.9e-17 62.5 0.0 1.1e-13 51.1 0.0 4.4 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE24939.1 - 1.3e-13 51.4 0.0 0.00097 19.7 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE24939.1 - 4.1e-08 33.6 0.0 0.011 16.4 0.0 5.0 3 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE24939.1 - 0.00035 20.8 0.0 2 9.2 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EPE24939.1 - 0.00069 19.9 1.0 5.2 7.7 0.5 4.0 4 0 0 4 4 4 2 Ankyrin repeat YPEB PF14620.6 EPE24939.1 - 0.15 11.4 0.6 0.3 10.4 0.6 1.4 1 0 0 1 1 1 0 YpeB sporulation Pre-PUA PF17832.1 EPE24940.1 - 5.5e-23 81.5 0.3 7.4e-23 81.1 0.3 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EPE24940.1 - 1.6e-14 53.6 0.6 1.6e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 PUA domain RE_HaeIII PF09556.10 EPE24940.1 - 0.031 13.4 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 HaeIII restriction endonuclease DUF1947 PF09183.10 EPE24940.1 - 0.052 13.8 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) DUF1479 PF07350.12 EPE24940.1 - 0.056 12.2 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Abhydrolase_3 PF07859.13 EPE24941.1 - 3.4e-24 85.9 0.0 4.5e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EPE24941.1 - 5.9e-12 45.1 0.0 1.7e-09 37.1 0.0 2.5 2 1 0 2 2 2 2 Steryl acetyl hydrolase COesterase PF00135.28 EPE24941.1 - 0.0029 16.5 0.0 0.0048 15.8 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family SGTA_dimer PF16546.5 EPE24942.1 - 3.4e-23 81.2 0.1 6.9e-23 80.2 0.1 1.5 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 EPE24942.1 - 1.5e-13 49.7 2.2 0.00013 21.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EPE24942.1 - 1.3e-12 47.0 0.8 9.7e-05 22.0 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EPE24942.1 - 5.7e-08 32.4 1.2 0.24 11.7 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EPE24942.1 - 7.8e-08 32.8 7.8 0.00017 22.2 4.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EPE24942.1 - 1.5e-07 31.0 0.3 0.00071 19.2 0.0 2.7 1 1 2 3 3 3 2 TPR repeat STI1 PF17830.1 EPE24942.1 - 8.8e-05 22.4 11.2 0.0015 18.4 7.6 2.4 2 0 0 2 2 2 1 STI1 domain TPR_17 PF13431.6 EPE24942.1 - 0.0002 21.5 2.8 0.095 13.1 0.0 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EPE24942.1 - 0.00021 21.9 3.7 0.12 13.3 1.3 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPE24942.1 - 0.00048 20.6 0.3 0.0095 16.4 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPE24942.1 - 0.0025 18.0 0.9 0.03 14.6 0.2 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EPE24942.1 - 0.013 15.3 0.3 0.41 10.6 0.2 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EPE24942.1 - 0.02 14.9 0.1 4.8 7.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 EPE24942.1 - 0.075 13.5 0.6 2.8 8.4 0.5 2.1 1 1 1 2 2 2 0 Bacterial transcriptional activator domain XPC-binding PF09280.11 EPE24942.1 - 0.099 12.4 2.6 0.1 12.3 0.8 1.9 2 0 0 2 2 2 0 XPC-binding domain TPR_9 PF13371.6 EPE24942.1 - 0.19 11.9 0.5 1.1 9.4 0.6 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat ABC_tran PF00005.27 EPE24943.1 - 2.5e-35 122.0 0.5 5.1e-35 121.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 EPE24943.1 - 2.5e-22 79.8 4.6 7.5e-22 78.3 4.6 1.9 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_15 PF13175.6 EPE24943.1 - 1.1e-05 25.3 0.0 4.4e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EPE24943.1 - 1.7e-05 24.4 0.0 0.00025 20.6 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EPE24943.1 - 0.028 14.3 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 EPE24943.1 - 0.053 13.3 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EPE24943.1 - 0.079 12.7 0.3 0.21 11.3 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PAM2 PF07145.15 EPE24943.1 - 0.17 11.6 0.0 0.49 10.2 0.0 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region AAA_23 PF13476.6 EPE24943.1 - 5 7.6 12.7 1.5 9.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain APG6_N PF17675.1 EPE24944.1 - 0.78 10.3 41.7 0.58 10.7 21.5 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Cep57_CLD PF14073.6 EPE24944.1 - 1 9.4 41.6 0.89 9.6 9.0 2.9 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 CALCOCO1 PF07888.11 EPE24944.1 - 2.8 6.7 45.0 0.95 8.3 37.0 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cyt-b5 PF00173.28 EPE24946.1 - 3.1e-13 49.7 0.0 3.9e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Inositol_P PF00459.25 EPE24947.1 - 1.2e-72 244.7 0.0 1.3e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family AP_endonuc_2 PF01261.24 EPE24948.1 - 3e-29 102.0 0.0 1.1e-28 100.1 0.0 1.7 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Shikimate_dh_N PF08501.11 EPE24949.1 - 1e-21 76.9 0.0 1.8e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EPE24949.1 - 0.0031 17.3 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EPE24949.1 - 0.0078 16.3 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EPE24949.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pro_CA PF00484.19 EPE24950.1 - 1.8e-11 44.6 0.3 4.3e-11 43.4 0.3 1.7 1 1 0 1 1 1 1 Carbonic anhydrase Sugar_tr PF00083.24 EPE24951.1 - 1.4e-135 452.7 26.1 1.6e-135 452.5 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE24951.1 - 2.7e-23 82.5 43.5 8.3e-22 77.6 40.5 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Pribosyltran_N PF13793.6 EPE24952.1 - 9e-40 135.2 0.1 2.8e-39 133.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EPE24952.1 - 3.3e-32 112.0 0.0 6.6e-28 98.0 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EPE24952.1 - 8.2e-07 28.7 0.0 2.1e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain XPG_I_2 PF12813.7 EPE24953.1 - 6.1e-54 183.1 0.0 9.2e-54 182.5 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing K_trans PF02705.16 EPE24954.1 - 1.4e-183 611.3 13.3 1.6e-183 611.0 13.3 1.0 1 0 0 1 1 1 1 K+ potassium transporter Sugar_tr PF00083.24 EPE24955.1 - 1.5e-82 277.9 21.1 1.7e-82 277.7 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE24955.1 - 2.1e-19 69.7 49.0 1.5e-15 57.0 19.5 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Gly-zipper_YMGG PF13441.6 EPE24955.1 - 0.4 10.5 6.3 1.3 8.9 6.3 1.9 1 0 0 1 1 1 0 YMGG-like Gly-zipper OATP PF03137.20 EPE24955.1 - 0.98 7.6 10.8 2 6.6 0.1 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Rick_17kDa_Anti PF05433.15 EPE24955.1 - 3.6 7.5 12.1 0.62 10.0 7.4 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain Trep_Strep PF09605.10 EPE24955.1 - 9.7 6.1 16.7 0.72 9.8 0.1 3.9 2 1 1 4 4 4 0 Hypothetical bacterial integral membrane protein (Trep_Strep) MiAMP1 PF09117.10 EPE24959.1 - 0.4 10.9 3.9 4.7 7.5 0.6 2.7 1 1 1 2 2 2 0 MiAMP1 DegT_DnrJ_EryC1 PF01041.17 EPE24960.1 - 1.1e-78 265.1 0.0 1.3e-78 264.8 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EPE24960.1 - 3.6e-08 33.0 0.2 1.1e-07 31.4 0.2 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPE24960.1 - 1.5e-07 30.7 0.2 2.1e-07 30.2 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 EPE24960.1 - 8.2e-07 28.1 0.7 2.1e-06 26.8 0.7 1.6 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 EPE24960.1 - 0.00018 20.2 0.2 0.00024 19.7 0.2 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Phage_tail_APC PF16778.5 EPE24960.1 - 0.18 11.7 0.4 0.4 10.6 0.4 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone protein MFS_1 PF07690.16 EPE24961.1 - 2.3e-40 138.6 31.0 2.3e-40 138.6 31.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE24961.1 - 2.7e-14 52.9 24.1 1.4e-13 50.5 24.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Thymosin PF01290.20 EPE24961.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Thymosin beta-4 family OATP PF03137.20 EPE24961.1 - 0.13 10.5 6.8 0.25 9.6 5.9 1.7 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Bac_luciferase PF00296.20 EPE24962.1 - 7e-53 180.1 0.0 1e-52 179.5 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Fungal_trans PF04082.18 EPE24963.1 - 2.1e-25 89.2 0.2 3.4e-25 88.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE24963.1 - 9.1e-10 38.5 9.5 1.6e-09 37.8 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gifsy-2 PF13856.6 EPE24963.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 ATP-binding sugar transporter from pro-phage Transp_cyt_pur PF02133.15 EPE24965.1 - 8.1e-63 212.7 35.3 9.5e-63 212.5 35.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Meckelin PF09773.9 EPE24965.1 - 0.13 10.4 2.3 0.19 9.8 2.3 1.3 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Pox_A14 PF05767.12 EPE24965.1 - 4.4 7.5 7.8 3.2 8.0 0.2 3.6 3 1 0 3 3 3 0 Poxvirus virion envelope protein A14 Bac_luciferase PF00296.20 EPE24966.1 - 4e-55 187.4 0.2 5.5e-55 187.0 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase AAA_16 PF13191.6 EPE24970.1 - 1.9e-08 34.9 0.1 4.5e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EPE24970.1 - 0.0056 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.13 EPE24970.1 - 0.021 14.0 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 EPE24970.1 - 0.021 14.4 0.1 0.074 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EPE24970.1 - 0.03 13.8 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EPE24970.1 - 0.12 12.7 0.3 0.4 11.0 0.3 1.8 1 1 0 1 1 1 0 AAA domain Myb_DNA-binding PF00249.31 EPE24972.1 - 5.2e-15 55.4 9.6 1.5e-07 31.5 0.5 3.7 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPE24972.1 - 4.6e-13 49.2 13.4 1.7e-09 37.7 3.3 3.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EPE24972.1 - 3.6 8.0 15.2 0.4 11.1 2.6 3.8 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain ADH_N_2 PF16884.5 EPE24973.1 - 5.6e-32 109.9 0.0 1.1e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase MFS_1 PF07690.16 EPE24973.1 - 1.7e-31 109.5 40.4 7.4e-31 107.3 40.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily ADH_zinc_N PF00107.26 EPE24973.1 - 5e-22 78.3 0.1 1.1e-21 77.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE24973.1 - 3.5e-05 24.9 0.0 8.4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Orf78 PF06024.12 EPE24973.1 - 0.057 13.7 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 Orf78 (ac78) AA_permease PF00324.21 EPE24974.1 - 5.4e-141 470.5 48.9 6.5e-141 470.2 48.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE24974.1 - 6.1e-31 107.7 55.0 7.6e-31 107.4 55.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF202 PF02656.15 EPE24976.1 - 2.1 8.8 7.6 20 5.7 1.7 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF202) EI24 PF07264.11 EPE24977.1 - 1.6e-11 44.7 12.9 2.6e-11 44.1 12.9 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Mid2 PF04478.12 EPE24979.1 - 0.00035 20.4 0.1 0.00064 19.6 0.1 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Gly-zipper_YMGG PF13441.6 EPE24979.1 - 0.027 14.2 2.6 0.06 13.1 2.6 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Beta-APP PF03494.13 EPE24979.1 - 0.51 10.2 2.7 2.1 8.2 2.4 2.0 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) ADPRTs_Tse2 PF18648.1 EPE24980.1 - 0.042 13.9 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins Pkinase PF00069.25 EPE24981.1 - 9.8e-71 238.2 0.0 1.2e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE24981.1 - 3e-28 98.8 0.0 4e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE24981.1 - 4.5e-07 29.5 0.0 6.9e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EPE24981.1 - 0.00012 21.1 0.0 0.00018 20.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EPE24981.1 - 0.00037 19.9 0.0 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPE24981.1 - 0.00037 20.5 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family PAP2_3 PF14378.6 EPE24982.1 - 4.4e-24 85.2 16.3 4.4e-24 85.2 16.3 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EPE24982.1 - 4.2e-09 36.3 5.5 4.2e-09 36.3 5.5 2.6 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 EPE24982.1 - 8.7 7.0 10.6 0.85 10.2 2.8 2.6 3 0 0 3 3 3 0 PAP2 superfamily C-terminal MFS_1 PF07690.16 EPE24983.1 - 1.5e-22 80.0 62.2 4e-13 49.0 34.5 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EPE24983.1 - 7.8e-09 34.5 30.0 1.1e-08 34.0 30.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Trehalase PF01204.18 EPE24983.1 - 0.037 12.9 0.1 0.061 12.1 0.1 1.2 1 0 0 1 1 1 0 Trehalase Zn_clus PF00172.18 EPE24984.1 - 8.8e-06 25.8 13.0 1.6e-05 25.0 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE24984.1 - 0.00086 18.2 0.9 0.0011 17.8 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 EPE24985.1 - 2.4e-26 92.1 0.7 3.9e-26 91.4 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE24985.1 - 0.0015 18.6 0.1 0.004 17.2 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Sulfotransfer_4 PF17784.1 EPE24986.1 - 3.6e-49 167.5 0.0 4.2e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EPE24986.1 - 0.0028 18.1 0.0 0.0038 17.6 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Zn_clus PF00172.18 EPE24988.1 - 2.1e-06 27.7 7.5 3.5e-06 27.0 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE24988.1 - 6.3e-06 25.2 0.1 1.2e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.7 EPE24989.1 - 3.1e-07 31.2 1.1 4e-07 30.9 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE24989.1 - 1.3e-05 25.0 0.3 5.6e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Glyco_hydro_61 PF03443.14 EPE24990.1 - 6.6e-49 166.6 0.1 1.1e-48 165.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EPE24990.1 - 1.7e-11 43.9 8.4 4.6e-11 42.5 8.4 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain MFS_1 PF07690.16 EPE24992.1 - 2.6e-39 135.2 43.9 1.4e-36 126.1 26.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE24992.1 - 2.3e-08 33.4 11.3 2.3e-08 33.4 11.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EPE24992.1 - 0.03 12.6 4.2 0.17 10.2 4.2 2.1 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Pam17 PF08566.10 EPE24992.1 - 0.3 10.9 0.6 1.2 9.0 0.0 2.2 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 Isochorismatase PF00857.20 EPE24993.1 - 7.9e-25 88.0 0.0 1e-24 87.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Cro PF09048.10 EPE24993.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Cro HK PF02110.15 EPE24994.1 - 2.8e-76 256.2 3.2 4.7e-76 255.4 3.2 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EPE24994.1 - 5.9e-57 191.9 2.0 1.2e-56 191.0 2.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 EPE24994.1 - 4.9e-05 22.9 1.3 8.7e-05 22.1 0.2 1.9 2 0 0 2 2 2 1 Carbohydrate kinase eIF-5_eIF-2B PF01873.17 EPE24995.1 - 3.4e-39 133.4 0.0 6.7e-39 132.4 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EPE24995.1 - 5.8e-21 74.4 0.2 5.8e-21 74.4 0.2 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon HEAT PF02985.22 EPE24996.1 - 0.00071 19.6 0.6 1.9 9.0 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat RelB PF04221.12 EPE24996.1 - 0.066 13.2 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 RelB antitoxin Arm PF00514.23 EPE24996.1 - 0.7 10.0 2.6 52 4.1 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DNA_pol_lambd_f PF10391.9 EPE24997.1 - 1.2e-17 63.4 1.3 2.1e-17 62.7 0.3 2.0 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 EPE24997.1 - 2.4e-17 63.2 0.0 9.5e-17 61.3 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EPE24997.1 - 3.2e-17 62.5 0.1 8.4e-17 61.1 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.6 EPE24997.1 - 2.7e-09 37.3 0.3 6.6e-08 32.8 0.3 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.6 EPE24997.1 - 0.00086 19.9 0.0 0.002 18.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 EPE24997.1 - 0.23 11.8 0.8 1.6 9.1 0.0 2.8 3 1 0 3 3 3 0 Nucleotidyltransferase domain TFIIE_alpha PF02002.17 EPE24998.1 - 1.8e-14 53.4 0.0 3.2e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit Zn_ribbon_SprT PF17283.2 EPE24998.1 - 0.1 12.5 0.0 13 5.8 0.0 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain NOA36 PF06524.12 EPE24998.1 - 9.2 5.5 10.8 13 5.0 5.0 2.2 2 0 0 2 2 2 0 NOA36 protein PseudoU_synth_1 PF01416.20 EPE24999.1 - 5.5e-08 33.2 0.0 1.3e-06 28.8 0.0 2.6 2 0 0 2 2 2 1 tRNA pseudouridine synthase Sec31 PF11549.8 EPE24999.1 - 0.19 11.6 1.7 0.41 10.6 1.7 1.5 1 0 0 1 1 1 0 Protein transport protein SEC31 Mito_carr PF00153.27 EPE25000.1 - 1.3e-65 217.4 3.4 3.1e-21 75.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein bVLRF1 PF18826.1 EPE25000.1 - 0.093 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor SseB PF07179.12 EPE25000.1 - 0.13 12.5 0.1 25 5.2 0.0 2.3 2 0 0 2 2 2 0 SseB protein N-terminal domain Cofilin_ADF PF00241.20 EPE25001.1 - 4.3e-41 139.5 0.0 1.4e-22 79.7 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Med22 PF06179.12 EPE25002.1 - 1.1e-19 70.6 0.0 2.4e-19 69.5 0.0 1.5 2 0 0 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF3517 PF12030.8 EPE25003.1 - 7.1e-102 340.8 0.0 2.3e-101 339.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH PF00443.29 EPE25003.1 - 1.6e-39 136.0 0.7 3.5e-39 134.8 0.7 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPE25003.1 - 1.5e-23 83.9 0.7 1.5e-23 83.9 0.7 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_P_pop3 PF08228.11 EPE25004.1 - 4.5e-13 49.5 0.1 4e-10 40.0 0.0 2.6 3 0 0 3 3 3 2 RNase P subunit Pop3 GP67 PF17634.2 EPE25005.1 - 0.036 14.5 3.1 0.094 13.1 3.1 1.7 1 0 0 1 1 1 0 Gene product 67 ADH_N PF08240.12 EPE25006.1 - 1.2e-06 28.4 0.0 5.7e-05 23.0 0.0 2.2 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE25006.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MAPEG PF01124.18 EPE25007.1 - 1e-20 73.9 1.5 1.3e-20 73.6 1.5 1.1 1 0 0 1 1 1 1 MAPEG family HET PF06985.11 EPE25008.1 - 6.3e-30 104.4 2.1 1.2e-29 103.6 2.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-TFIIIC PF12660.7 EPE25008.1 - 0.084 12.8 0.5 0.18 11.7 0.5 1.5 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex PRCC PF10253.9 EPE25009.1 - 3.3e-36 126.1 15.3 3.3e-36 126.1 15.3 3.0 1 1 2 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting DUF4663 PF15668.5 EPE25009.1 - 0.58 9.2 6.5 0.98 8.4 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) CRIM PF16978.5 EPE25010.1 - 1.8e-45 154.6 0.1 3.5e-45 153.6 0.1 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EPE25010.1 - 1.5e-35 121.8 0.0 3.3e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 EPE25010.1 - 0.0026 18.0 0.3 0.009 16.2 0.0 2.0 2 0 0 2 2 2 1 TUG ubiquitin-like domain RBD PF02196.15 EPE25010.1 - 0.012 15.6 0.1 0.026 14.6 0.1 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain DUF5583 PF17821.1 EPE25010.1 - 0.16 11.9 1.2 0.33 10.9 0.4 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5583) Hid1 PF12722.7 EPE25011.1 - 6.2 4.8 9.1 6.7 4.7 9.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RIFIN PF02009.16 EPE25011.1 - 8.8 6.1 6.6 12 5.7 6.6 1.2 1 0 0 1 1 1 0 Rifin Glyco_transf_8 PF01501.20 EPE25012.1 - 0.12 11.9 0.6 5.9 6.4 0.1 2.3 2 1 0 2 2 2 0 Glycosyl transferase family 8 Anillin PF08174.11 EPE25016.1 - 7e-17 62.2 0.0 1.8e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 EPE25016.1 - 3.6e-08 33.9 0.0 2.5e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 PH domain SET PF00856.28 EPE25017.1 - 3.4e-13 50.3 0.0 2.9e-12 47.3 0.0 2.2 1 1 0 1 1 1 1 SET domain SAF PF08666.12 EPE25017.1 - 0.023 15.3 0.1 9 7.0 0.0 2.4 2 0 0 2 2 2 0 SAF domain PASTA PF03793.19 EPE25017.1 - 0.13 12.1 0.1 0.38 10.6 0.1 1.8 1 0 0 1 1 1 0 PASTA domain DUF4213 PF13938.6 EPE25018.1 - 0.034 14.4 0.0 0.99 9.7 0.0 2.4 2 0 0 2 2 2 0 Putative heavy-metal chelation SKG6 PF08693.10 EPE25019.1 - 0.00078 18.8 0.5 0.0017 17.7 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.7 EPE25019.1 - 0.055 12.9 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity adh_short_C2 PF13561.6 EPE25020.1 - 1.4e-57 195.0 0.0 1.6e-57 194.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE25020.1 - 1.1e-47 162.0 0.0 1.4e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE25020.1 - 1.1e-06 28.7 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KR domain F-box-like PF12937.7 EPE25022.1 - 0.047 13.6 0.2 0.17 11.8 0.2 2.1 1 0 0 1 1 1 0 F-box-like SprT-like PF10263.9 EPE25023.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 SprT-like family WLM PF08325.10 EPE25023.1 - 0.21 11.6 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 WLM domain CENP-B_dimeris PF09026.10 EPE25024.1 - 9.6 6.7 8.7 18 5.8 8.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C2H2 PF00096.26 EPE25027.1 - 0.00025 21.3 5.1 0.0042 17.5 0.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE25027.1 - 0.13 13.2 3.9 0.18 12.7 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger PNGaseA PF12222.8 EPE25028.1 - 8.8e-136 453.2 7.4 2e-135 452.0 3.5 2.0 1 1 1 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Acetyltransf_2 PF00797.17 EPE25029.1 - 6.1e-31 108.1 0.1 5.2e-29 101.7 0.1 2.8 1 1 0 1 1 1 1 N-acetyltransferase zf-C3HC4_3 PF13920.6 EPE25030.1 - 0.002 18.0 11.6 0.0031 17.3 11.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EPE25030.1 - 0.0058 16.5 6.1 0.0092 15.8 6.1 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EPE25030.1 - 1.8 8.6 11.9 2.9 7.9 11.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 EPE25030.1 - 7.1 6.6 12.6 12 5.8 12.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Say1_Mug180 PF10340.9 EPE25031.1 - 4.6e-21 75.1 0.0 1.2e-13 50.7 0.1 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EPE25031.1 - 1.7e-19 70.5 0.0 2.9e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold U3_snoRNA_assoc PF08297.11 EPE25032.1 - 1.3e-12 48.2 1.3 1.3e-12 48.2 1.3 2.5 2 1 0 2 2 2 1 U3 snoRNA associated SAP PF02037.27 EPE25033.1 - 8.8e-11 41.3 0.5 8.8e-11 41.3 0.5 2.1 3 0 0 3 3 3 1 SAP domain RSB_motif PF16294.5 EPE25033.1 - 4.8e-07 30.0 2.6 2.1e-06 27.9 0.1 2.8 2 0 0 2 2 2 1 RNSP1-SAP18 binding (RSB) motif Cyclin_C_2 PF16899.5 EPE25033.1 - 0.14 12.6 0.2 0.66 10.4 0.1 2.1 2 0 0 2 2 2 0 Cyclin C-terminal domain TFIIB PF00382.19 EPE25033.1 - 0.18 11.9 0.0 13 5.9 0.0 2.8 2 0 0 2 2 2 0 Transcription factor TFIIB repeat DUF676 PF05057.14 EPE25034.1 - 5.7e-43 147.0 0.2 2.6e-26 92.5 0.0 3.2 2 1 1 3 3 3 3 Putative serine esterase (DUF676) IBR PF01485.21 EPE25035.1 - 2.5e-10 40.4 44.5 1.2e-06 28.7 12.8 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain DUF2158 PF09926.9 EPE25035.1 - 0.029 14.1 0.2 0.058 13.1 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) RNase_H PF00075.24 EPE25036.1 - 5.1e-24 85.1 0.0 1e-23 84.1 0.0 1.5 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 EPE25036.1 - 0.002 17.9 0.0 0.047 13.5 0.0 2.3 1 1 0 1 1 1 1 Reverse transcriptase-like BACK PF07707.15 EPE25037.1 - 0.084 13.0 0.0 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 BTB And C-terminal Kelch CDC45 PF02724.14 EPE25037.1 - 0.11 10.8 16.5 0.01 14.2 4.8 2.1 2 0 0 2 2 2 0 CDC45-like protein RXT2_N PF08595.11 EPE25037.1 - 1 9.4 13.7 2.8 8.0 1.5 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF2052 PF09747.9 EPE25037.1 - 1.4 9.0 19.4 1.6 8.8 6.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Nop14 PF04147.12 EPE25037.1 - 2.7 6.1 22.6 0.039 12.2 10.4 2.1 2 0 0 2 2 2 0 Nop14-like family DASH_Spc34 PF08657.10 EPE25038.1 - 4.2e-45 154.5 8.3 1.1e-23 84.4 0.2 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 MAP65_ASE1 PF03999.12 EPE25038.1 - 0.0046 15.7 1.3 0.0061 15.3 1.3 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Nsp1_C PF05064.13 EPE25038.1 - 0.0078 16.0 2.3 1.3 8.9 1.4 2.3 1 1 1 2 2 2 1 Nsp1-like C-terminal region Laminin_II PF06009.12 EPE25038.1 - 0.015 15.3 0.2 4.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Laminin Domain II ATG16 PF08614.11 EPE25038.1 - 0.019 15.2 6.4 0.17 12.1 3.0 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 EPE25038.1 - 0.022 13.4 0.7 0.026 13.2 0.7 1.1 1 0 0 1 1 1 0 AAA domain Snapin_Pallidin PF14712.6 EPE25038.1 - 0.046 14.1 1.4 2 8.9 0.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Spc7 PF08317.11 EPE25038.1 - 0.06 12.2 5.3 0.085 11.7 5.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 EPE25038.1 - 0.074 13.2 12.8 0.27 11.4 10.9 2.1 1 1 1 2 2 2 0 Tropomyosin like DUF1664 PF07889.12 EPE25038.1 - 0.092 12.8 2.3 11 6.0 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) BBS2_C PF14782.6 EPE25038.1 - 0.15 10.8 0.9 0.27 10.0 0.9 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Tropomyosin PF00261.20 EPE25038.1 - 0.18 11.1 14.7 2 7.7 13.2 2.1 1 1 0 1 1 1 0 Tropomyosin Lebercilin PF15619.6 EPE25038.1 - 0.26 10.9 11.3 1.2 8.7 8.1 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Occludin_ELL PF07303.13 EPE25038.1 - 0.29 11.9 3.6 2 9.2 3.6 2.0 1 1 0 1 1 1 0 Occludin homology domain DASH_Spc19 PF08287.11 EPE25038.1 - 0.3 11.0 9.6 0.51 10.2 9.6 1.5 1 1 0 1 1 1 0 Spc19 Uds1 PF15456.6 EPE25038.1 - 0.41 10.8 5.2 0.72 10.0 5.2 1.4 1 0 0 1 1 1 0 Up-regulated During Septation UPF0242 PF06785.11 EPE25038.1 - 0.47 10.5 10.3 2 8.5 8.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 EPE25038.1 - 0.55 10.3 5.9 13 5.8 6.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.9 EPE25038.1 - 0.66 10.3 4.1 23 5.4 2.6 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.6 EPE25038.1 - 1.1 9.7 10.1 37 4.8 8.0 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF5082 PF16888.5 EPE25038.1 - 1.7 8.9 7.3 26 5.1 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF724 PF05266.14 EPE25038.1 - 1.8 8.4 6.0 3.6 7.4 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF3429 PF11911.8 EPE25041.1 - 9.5e-42 142.7 12.5 1.3e-41 142.3 12.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FAM176 PF14851.6 EPE25041.1 - 0.041 13.6 2.7 0.07 12.8 2.7 1.5 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 EPE25041.1 - 0.63 10.1 7.6 1.1 9.3 7.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Astro_capsid_p PF12226.8 EPE25041.1 - 1.5 7.9 8.1 2 7.5 8.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 EPE25041.1 - 2 6.6 11.4 2.6 6.2 11.4 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.16 EPE25041.1 - 3.2 6.9 5.8 4.9 6.3 5.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 EPE25041.1 - 6.4 6.0 13.7 8.6 5.6 13.7 1.1 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 EPE25044.1 - 6.7e-20 71.5 0.1 2.6e-15 56.5 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE25044.1 - 4.4e-13 49.1 0.1 3.3e-11 43.0 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase NUDE_C PF04880.13 EPE25044.1 - 5.7 7.4 7.2 13 6.2 7.2 1.6 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region His_Phos_1 PF00300.22 EPE25045.1 - 8e-27 94.2 0.2 1.9e-26 93.0 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF1168 PF06658.12 EPE25046.1 - 1.3e-35 122.2 9.1 1.3e-35 122.2 9.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1168) PPL5 PF18168.1 EPE25046.1 - 0.36 10.1 2.8 0.47 9.7 2.8 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_S49_N PF08496.10 EPE25046.1 - 1.8 8.6 5.2 3.1 7.8 5.2 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Cpn60_TCP1 PF00118.24 EPE25047.1 - 2.5e-169 564.0 1.8 2.9e-169 563.8 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family adh_short PF00106.25 EPE25048.1 - 1.1e-38 132.7 0.3 1.8e-38 132.0 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE25048.1 - 2.8e-30 105.6 0.1 3.7e-30 105.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE25048.1 - 1.1e-08 35.2 4.8 2.1e-07 31.0 4.8 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE25048.1 - 0.06 12.8 0.1 0.24 10.8 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family RF-1 PF00472.20 EPE25049.1 - 4.3e-13 49.2 2.4 7.6e-13 48.4 2.4 1.4 1 0 0 1 1 1 1 RF-1 domain DUF5390 PF17365.2 EPE25049.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5390) Bromodomain PF00439.25 EPE25050.1 - 1e-18 67.2 0.4 4.7e-18 65.0 0.1 2.1 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 EPE25050.1 - 3.4e-08 33.4 0.0 1.4e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Bromodomain associated BDHCT_assoc PF16204.5 EPE25050.1 - 6.1 6.5 13.6 0.46 10.1 7.5 2.0 2 0 0 2 2 2 0 BDHCT-box associated domain on Bloom syndrome protein VanZ PF04892.12 EPE25051.1 - 1.1e-06 29.3 1.0 1.5e-06 28.9 1.0 1.2 1 0 0 1 1 1 1 VanZ like family Nop PF01798.18 EPE25052.1 - 2e-87 292.5 0.0 2e-87 292.5 0.0 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EPE25052.1 - 4.7e-19 68.5 0.0 4.7e-19 68.5 0.0 3.0 4 0 0 4 4 4 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 EPE25052.1 - 0.023 14.8 25.5 0.042 13.9 25.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Vfa1 PF08432.10 EPE25052.1 - 6.2 7.1 19.6 9.8 6.5 19.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AAA PF00004.29 EPE25053.1 - 2.3e-42 144.5 0.0 3.8e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EPE25053.1 - 2.7e-28 97.8 0.1 9.1e-28 96.0 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EPE25053.1 - 4.1e-21 74.8 7.3 4.1e-21 74.8 7.3 2.0 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 EPE25053.1 - 9.7e-06 25.4 0.0 1.7e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EPE25053.1 - 1.1e-05 25.6 0.2 0.0038 17.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EPE25053.1 - 1.5e-05 25.0 0.0 7.7e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPE25053.1 - 2e-05 25.0 0.0 0.0014 19.1 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_lid_3 PF17862.1 EPE25053.1 - 4.2e-05 23.3 0.1 0.00054 19.7 0.0 2.7 3 0 0 3 3 3 1 AAA+ lid domain IstB_IS21 PF01695.17 EPE25053.1 - 5e-05 23.1 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EPE25053.1 - 7.8e-05 23.0 0.0 0.0098 16.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 EPE25053.1 - 0.00017 20.9 0.0 0.00031 20.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EPE25053.1 - 0.0002 21.6 0.1 0.0087 16.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EPE25053.1 - 0.00023 20.4 0.0 0.00088 18.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EPE25053.1 - 0.00029 20.9 0.0 0.00057 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EPE25053.1 - 0.00085 19.9 0.0 0.0026 18.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EPE25053.1 - 0.0023 18.1 0.0 0.005 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EPE25053.1 - 0.0027 17.5 0.0 0.0074 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EPE25053.1 - 0.01 15.4 0.1 0.67 9.5 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 EPE25053.1 - 0.013 16.0 0.0 0.038 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EPE25053.1 - 0.017 14.7 0.0 0.087 12.3 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EPE25053.1 - 0.027 13.8 0.1 0.077 12.4 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 EPE25053.1 - 0.037 14.1 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Torsin Cytidylate_kin PF02224.18 EPE25053.1 - 0.04 13.6 0.3 0.52 10.0 0.1 2.3 2 0 0 2 2 2 0 Cytidylate kinase USP8_dimer PF08969.11 EPE25053.1 - 0.041 14.1 4.0 0.15 12.3 3.4 2.1 2 0 0 2 2 2 0 USP8 dimerisation domain Parvo_NS1 PF01057.17 EPE25053.1 - 0.061 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 EPE25053.1 - 0.075 12.5 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 EPE25053.1 - 0.092 12.7 0.0 0.67 9.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 EPE25053.1 - 0.13 11.5 0.1 1.5 8.0 0.0 2.3 1 1 1 2 2 2 0 Zeta toxin AFG1_ATPase PF03969.16 EPE25053.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Sigma54_activat PF00158.26 EPE25053.1 - 0.16 11.7 0.0 0.46 10.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EPE25053.1 - 0.2 11.5 0.6 1.2 8.9 0.0 2.3 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Prefoldin_2 PF01920.20 EPE25054.1 - 1.7e-17 63.3 6.5 1.7e-17 63.3 6.5 2.0 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.6 EPE25054.1 - 4.3e-06 26.7 5.4 1.3e-05 25.2 5.4 1.8 1 1 0 1 1 1 1 Prefoldin subunit MIP-T3_C PF17749.1 EPE25054.1 - 0.0018 18.3 1.7 0.0018 18.3 1.7 2.4 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region DUF1515 PF07439.11 EPE25054.1 - 0.0019 18.2 2.5 0.031 14.3 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1515) Sec34 PF04136.15 EPE25054.1 - 0.68 9.8 6.4 2.1 8.2 0.1 2.9 2 1 1 3 3 3 0 Sec34-like family Atg14 PF10186.9 EPE25054.1 - 0.69 8.9 6.6 0.83 8.7 6.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CCDC-167 PF15188.6 EPE25054.1 - 2.2 8.7 6.5 1.5 9.2 0.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DivIC PF04977.15 EPE25054.1 - 9.2 6.1 16.5 2.7 7.8 1.5 3.2 3 0 0 3 3 3 0 Septum formation initiator Acetyltransf_1 PF00583.25 EPE25055.1 - 8.1e-11 42.2 0.0 9.3e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE25055.1 - 9.3e-09 35.6 0.0 1.3e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPE25055.1 - 1.2e-08 35.0 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE25055.1 - 0.00026 20.9 0.0 0.00045 20.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EPE25055.1 - 0.016 15.4 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EPE25055.1 - 0.02 14.9 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 EPE25056.1 - 1.2e-53 182.1 0.0 1.6e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE25056.1 - 3e-32 111.9 0.0 3.8e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE25056.1 - 0.00012 21.5 0.0 0.00035 20.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EPE25056.1 - 0.0022 17.4 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPE25056.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EPE25056.1 - 0.023 13.5 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EPE25056.1 - 0.038 12.9 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EPE25056.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.6 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 CSN8_PSD8_EIF3K PF10075.9 EPE25058.1 - 7.7e-07 29.2 0.0 1.5e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EPE25058.1 - 0.0013 18.1 0.2 0.0019 17.7 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP family HlyIII PF03006.20 EPE25059.1 - 9.1e-64 215.2 14.3 1.1e-63 215.0 14.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related TMEM238 PF15125.6 EPE25059.1 - 0.055 13.7 0.9 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 TMEM238 protein family DUF4405 PF14358.6 EPE25059.1 - 0.12 13.0 12.3 0.17 12.4 1.1 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4405) Ni_hydr_CYTB PF01292.20 EPE25059.1 - 0.3 10.7 10.1 0.083 12.5 5.3 2.2 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 TssN PF17555.2 EPE25059.1 - 3.2 7.1 8.4 0.86 8.9 2.4 2.3 1 1 1 2 2 2 0 Type VI secretion system, TssN Annexin PF00191.20 EPE25061.1 - 6.1e-67 221.6 10.0 6.8e-18 64.5 0.2 4.2 4 0 0 4 4 4 4 Annexin MiaE PF06175.11 EPE25061.1 - 0.019 14.6 0.1 0.028 14.0 0.1 1.2 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) Mei5_like PF17021.5 EPE25061.1 - 0.091 12.8 0.5 2.7 8.0 0.1 2.5 2 0 0 2 2 2 0 Putative double-strand recombination repair-like zf-C2H2 PF00096.26 EPE25062.1 - 0.097 13.2 5.7 0.61 10.6 0.8 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 EPE25062.1 - 0.098 13.1 0.6 0.27 11.7 0.6 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EPE25062.1 - 0.45 11.5 5.3 4.7 8.3 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger APH PF01636.23 EPE25063.1 - 4e-10 40.0 0.0 1.1e-09 38.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Dus PF01207.17 EPE25064.1 - 5e-48 163.8 0.0 6.3e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Fez1 PF06818.15 EPE25065.1 - 0.04 14.4 5.5 0.073 13.5 5.5 1.4 1 0 0 1 1 1 0 Fez1 CP12 PF02672.15 EPE25065.1 - 0.055 14.2 0.0 0.89 10.4 0.0 2.6 1 1 1 2 2 2 0 CP12 domain Spc7 PF08317.11 EPE25065.1 - 0.068 12.0 6.2 0.1 11.4 6.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Hydrolase_6 PF13344.6 EPE25066.1 - 1e-20 73.7 0.0 2.3e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPE25066.1 - 3e-19 68.8 0.0 1.1e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EPE25066.1 - 0.0074 16.6 0.0 5.5 7.2 0.0 3.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Aldo_ket_red PF00248.21 EPE25067.1 - 1.1e-51 175.8 0.1 4.4e-51 173.8 0.1 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Cyclin_N PF00134.23 EPE25070.1 - 5.8e-13 48.7 0.3 1.9e-12 47.0 0.3 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 EPE25070.1 - 0.0056 16.7 0.8 0.019 15.0 0.1 2.1 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 EPE25070.1 - 0.012 15.7 0.0 1 9.5 0.0 2.6 2 0 0 2 2 2 0 Cyclin, C-terminal domain RHD_dimer PF16179.5 EPE25070.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Rel homology dimerisation domain Abhydrolase_3 PF07859.13 EPE25071.1 - 2.2e-41 142.0 0.0 2.7e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EPE25071.1 - 2.7e-06 26.6 0.2 7.2e-06 25.1 0.2 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EPE25071.1 - 0.023 14.2 0.4 6.1 6.3 0.1 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EPE25071.1 - 0.042 13.7 0.1 0.11 12.3 0.2 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.18 EPE25071.1 - 0.12 11.9 0.1 9.6 5.7 0.1 2.6 2 1 0 2 2 2 0 Dienelactone hydrolase family F-box-like PF12937.7 EPE25072.1 - 6.5e-05 22.7 0.4 0.00023 21.0 0.4 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 EPE25072.1 - 0.011 15.5 9.3 0.047 13.4 1.8 3.2 2 1 0 2 2 2 0 Leucine rich repeat STAC2_u1 PF16664.5 EPE25072.1 - 3.3 8.2 13.6 1.8 9.1 3.3 2.7 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 SPX PF03105.19 EPE25072.1 - 8 6.3 10.2 0.25 11.2 1.6 2.1 2 0 0 2 2 2 0 SPX domain AKNA PF12443.8 EPE25073.1 - 0.04 14.6 0.1 0.072 13.7 0.1 1.3 1 0 0 1 1 1 0 AT-hook-containing transcription factor DUF1515 PF07439.11 EPE25073.1 - 0.048 13.7 2.2 0.062 13.3 0.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) GhoS PF11080.8 EPE25073.1 - 0.095 12.7 0.0 0.27 11.2 0.0 1.8 1 1 0 1 1 1 0 Endoribonuclease GhoS DUF1765 PF08578.10 EPE25075.1 - 7.1e-46 155.7 10.8 7.1e-46 155.7 10.8 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1765) TFR_dimer PF04253.15 EPE25076.1 - 3.5e-36 123.9 0.0 7.6e-36 122.9 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EPE25076.1 - 1.8e-24 86.5 0.0 3.6e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EPE25076.1 - 3.8e-13 49.3 0.0 9.2e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 PA domain Vps35 PF03635.17 EPE25077.1 - 2.2e-293 975.3 10.4 2.8e-291 968.4 10.4 2.0 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ribonuc_L-PSP PF01042.21 EPE25077.1 - 0.065 13.2 0.2 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 Endoribonuclease L-PSP BING4CT PF08149.11 EPE25077.1 - 0.093 12.5 0.7 0.22 11.4 0.7 1.6 1 0 0 1 1 1 0 BING4CT (NUC141) domain RPAP3_C PF13877.6 EPE25077.1 - 0.22 12.1 2.8 7.8 7.1 0.4 4.0 3 1 0 3 3 3 0 Potential Monad-binding region of RPAP3 DUF4746 PF15928.5 EPE25077.1 - 0.73 9.2 6.5 1.3 8.4 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Spore_coat_CotO PF14153.6 EPE25077.1 - 3.5 7.5 8.3 7.9 6.4 8.3 1.5 1 0 0 1 1 1 0 Spore coat protein CotO FAD_binding_4 PF01565.23 EPE25079.1 - 2.5e-20 72.6 0.4 4.5e-20 71.8 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE25079.1 - 0.02 15.0 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like GTP_EFTU PF00009.27 EPE25082.1 - 6.7e-56 188.9 0.0 9.8e-56 188.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EPE25082.1 - 4.6e-25 87.5 0.0 9.6e-25 86.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EPE25082.1 - 2.5e-15 56.3 0.0 5.3e-08 32.8 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EPE25082.1 - 8.4e-07 29.3 0.0 1.8e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 EPE25082.1 - 0.00047 19.9 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G, domain IV RF3_C PF16658.5 EPE25082.1 - 0.00062 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain PX PF00787.24 EPE25083.1 - 1.4e-10 41.1 0.0 2.6e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EPE25083.1 - 6.7e-09 35.6 0.3 1.4e-08 34.6 0.3 1.5 1 0 0 1 1 1 1 Vps5 C terminal like CCT_2 PF09425.10 EPE25083.1 - 0.33 10.9 4.6 9.2 6.3 0.1 2.7 2 0 0 2 2 2 0 Divergent CCT motif Suf PF05843.14 EPE25083.1 - 4.5 7.2 7.7 7.9 6.4 7.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 EPE25083.1 - 8.1 6.3 14.9 1.6 8.7 10.8 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ADH_N PF08240.12 EPE25084.1 - 3.1e-26 91.4 2.4 6.8e-26 90.3 2.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE25084.1 - 5.1e-17 62.1 0.1 2.9e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EPE25084.1 - 1.7e-08 34.2 0.8 0.0023 17.5 0.1 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EPE25084.1 - 0.0023 19.0 0.0 0.0052 17.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPE25084.1 - 0.003 16.9 0.1 0.003 16.9 0.1 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EPE25084.1 - 0.016 14.5 0.2 0.17 11.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EPE25084.1 - 0.021 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.18 EPE25084.1 - 0.035 14.3 0.0 0.066 13.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 EPE25084.1 - 0.038 14.0 0.0 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 EPE25084.1 - 0.042 13.4 0.5 0.085 12.4 0.1 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EPE25084.1 - 0.043 13.7 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.9 EPE25084.1 - 0.085 12.9 0.4 0.22 11.6 0.4 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region DUF281 PF03436.13 EPE25084.1 - 0.088 13.2 0.6 0.62 10.5 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF281) ApbA PF02558.16 EPE25084.1 - 0.092 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EPE25084.1 - 0.097 12.0 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EPE25084.1 - 0.13 12.5 0.2 0.44 10.8 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MitMem_reg PF13012.6 EPE25085.1 - 1.7e-15 57.4 0.2 5.9e-15 55.7 0.2 1.9 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EPE25085.1 - 9.4e-11 41.7 0.0 1.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ArfGap PF01412.18 EPE25088.1 - 4.8e-31 107.3 0.0 9.3e-31 106.3 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.22 EPE25089.1 - 6e-30 102.9 0.5 6.4e-13 48.3 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPE25089.1 - 7.5e-05 22.3 0.0 0.96 9.1 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPE25089.1 - 0.002 18.2 0.0 0.042 14.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif DbpA PF03880.15 EPE25089.1 - 0.026 14.5 0.2 4.7 7.3 0.1 2.8 3 0 0 3 3 3 0 DbpA RNA binding domain PHM7_cyt PF14703.6 EPE25089.1 - 0.042 14.1 0.0 11 6.2 0.0 3.3 2 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF4944 PF16302.5 EPE25089.1 - 0.054 13.5 0.0 4.9 7.2 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4944) DLIC PF05783.11 EPE25089.1 - 0.071 11.9 0.7 2 7.2 0.3 2.3 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Limkain-b1 PF11608.8 EPE25089.1 - 0.076 13.1 0.3 13 6.0 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 FXMRP1_C_core PF12235.8 EPE25089.1 - 0.78 10.4 17.3 0.3 11.7 13.7 2.1 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Flavodoxin_1 PF00258.25 EPE25090.1 - 1.9e-33 115.7 0.0 3.6e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 EPE25090.1 - 5.1e-31 108.0 0.0 8.8e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EPE25090.1 - 7e-14 52.4 0.1 2.5e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 EPE25090.1 - 0.0025 17.5 0.0 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_5 PF12724.7 EPE25090.1 - 0.017 15.3 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain NHR2 PF08788.11 EPE25090.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 NHR2 domain like Cas_APE2256 PF09651.10 EPE25090.1 - 0.16 11.8 0.0 0.47 10.4 0.0 1.8 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_APE2256) p450 PF00067.22 EPE25091.1 - 1.6e-43 149.2 0.0 5.7e-31 107.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF4538 PF15061.6 EPE25091.1 - 0.49 10.2 2.5 4.7 7.0 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) 3Beta_HSD PF01073.19 EPE25092.1 - 1.1e-42 146.0 0.0 1.4e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPE25092.1 - 1.1e-27 97.1 0.0 1.5e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE25092.1 - 2.9e-14 53.2 0.0 4.4e-13 49.3 0.1 2.2 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EPE25092.1 - 1e-11 44.5 0.0 1.5e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EPE25092.1 - 2e-09 37.0 0.0 7.6e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 EPE25092.1 - 0.00015 21.0 0.0 0.0021 17.3 0.0 2.6 2 2 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EPE25092.1 - 0.0016 18.4 0.0 0.014 15.3 0.0 2.2 1 1 0 1 1 1 1 KR domain DAO PF01266.24 EPE25093.1 - 5e-34 118.4 0.0 5.8e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE25093.1 - 7.3e-05 22.9 0.0 0.00017 21.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EPE25093.1 - 0.022 14.0 0.0 0.075 12.3 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 EPE25093.1 - 0.055 12.7 0.0 6.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Bystin PF05291.11 EPE25094.1 - 2.9e-132 440.4 0.0 3.8e-132 440.0 0.0 1.1 1 0 0 1 1 1 1 Bystin GFO_IDH_MocA PF01408.22 EPE25096.1 - 1.2e-13 51.9 0.0 2.4e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EPE25096.1 - 6.4e-05 22.9 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DHquinase_I PF01487.15 EPE25098.1 - 8.6e-28 98.1 0.0 2.7e-27 96.5 0.0 1.7 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.22 EPE25098.1 - 2.2e-18 66.9 0.0 4.3e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.11 EPE25098.1 - 2.2e-14 53.4 0.0 5.5e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EPE25098.1 - 5.2e-09 35.7 0.5 9.8e-09 34.8 0.5 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EPE25098.1 - 2.5e-08 34.1 0.1 1.2e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EPE25098.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 EPE25098.1 - 0.13 12.9 0.1 0.52 10.9 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.18 EPE25099.1 - 8e-26 90.6 1.1 1.5e-25 89.7 1.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE25099.1 - 7.9e-08 32.3 13.5 1.3e-07 31.7 13.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTX PF02382.15 EPE25100.1 - 0.013 15.2 0.5 0.014 15.1 0.5 1.0 1 0 0 1 1 1 0 N-terminal domain in RTX protein Halogen_Hydrol PF10112.9 EPE25100.1 - 0.026 14.6 0.1 0.028 14.4 0.1 1.0 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Ysc84 PF04366.12 EPE25101.1 - 1.5e-45 154.0 0.1 2.4e-45 153.4 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator NAD_binding_6 PF08030.12 EPE25103.1 - 1.5e-18 67.4 0.0 2.4e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EPE25103.1 - 3e-16 59.7 9.6 3e-16 59.7 9.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EPE25103.1 - 2.2e-10 40.6 0.0 4.9e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EPE25103.1 - 0.026 15.2 0.0 0.15 12.7 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain PDR_assoc PF08370.11 EPE25103.1 - 3.6 7.4 7.2 16 5.3 0.8 2.5 2 0 0 2 2 2 0 Plant PDR ABC transporter associated DUF4407 PF14362.6 EPE25105.1 - 0.35 10.2 6.3 0.43 9.9 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Barwin PF00967.17 EPE25106.1 - 4.6e-05 23.3 0.5 0.0002 21.2 0.2 2.0 2 0 0 2 2 2 1 Barwin family DPBB_1 PF03330.18 EPE25106.1 - 9.3e-05 22.6 0.0 0.00041 20.6 0.0 2.1 1 0 0 1 1 1 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 EPE25106.1 - 0.0051 16.8 1.3 0.0097 15.9 1.3 1.4 1 0 0 1 1 1 1 Pollen allergen Cerato-platanin PF07249.12 EPE25106.1 - 0.27 11.4 3.4 0.21 11.7 0.4 2.3 1 1 1 2 2 2 0 Cerato-platanin Cytomega_UL20A PF05984.12 EPE25106.1 - 0.45 10.8 9.7 0.11 12.8 1.5 3.1 2 1 1 3 3 3 0 Cytomegalovirus UL20A protein Kelch_5 PF13854.6 EPE25108.1 - 0.00049 20.0 0.5 0.013 15.4 0.0 3.4 2 1 0 2 2 2 1 Kelch motif LRR_8 PF13855.6 EPE25109.1 - 7.6e-08 32.0 15.2 1.5e-06 27.9 3.1 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EPE25109.1 - 0.0077 16.6 6.3 0.0077 16.6 6.3 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Methyltrn_RNA_3 PF02598.17 EPE25110.1 - 3.2e-103 345.2 0.0 3.8e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase FMO-like PF00743.19 EPE25111.1 - 4e-45 154.3 0.1 8.4e-28 97.1 0.1 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EPE25111.1 - 2.8e-12 46.5 0.1 3.8e-08 32.9 0.1 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPE25111.1 - 7.6e-11 41.8 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPE25111.1 - 2.7e-10 39.9 0.1 3.7e-09 36.2 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EPE25111.1 - 1.9e-08 34.5 3.0 1.5e-06 28.3 0.1 4.2 4 2 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 EPE25111.1 - 2.3e-07 30.3 0.0 0.00062 19.1 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 EPE25111.1 - 2.6e-05 24.3 0.0 0.00013 22.2 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE25111.1 - 0.0012 18.5 0.0 0.58 9.7 0.0 3.0 4 0 0 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EPE25111.1 - 0.011 14.4 0.2 0.44 9.2 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.27 EPE25111.1 - 0.061 13.9 0.1 6.2 7.5 0.0 2.7 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 EPE25111.1 - 0.16 11.5 0.0 4.6 6.7 0.0 2.4 2 1 0 2 2 2 0 Glucose dehydrogenase C-terminus MAF_flag10 PF01973.18 EPE25111.1 - 0.36 10.5 1.2 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF115 IF4E PF01652.18 EPE25112.1 - 5.6e-56 188.7 0.2 8e-56 188.2 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E HDA2-3 PF11496.8 EPE25113.1 - 5.7e-08 32.3 0.0 0.0085 15.3 0.0 2.5 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 EPE25113.1 - 0.017 15.0 0.9 0.041 13.8 0.9 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_L4 PF00573.22 EPE25114.1 - 1.7e-33 116.0 0.2 2.2e-33 115.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EPE25114.1 - 6.6e-28 96.6 0.1 2.8e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DUF1382 PF07131.11 EPE25115.1 - 0.02 14.9 0.3 0.067 13.2 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) ELO PF01151.18 EPE25116.1 - 1.3e-63 214.9 18.7 1.5e-63 214.6 18.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family HET PF06985.11 EPE25117.1 - 8.8e-28 97.5 0.0 1.8e-27 96.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) COX5A PF02284.16 EPE25118.1 - 1.8e-41 140.3 0.2 2.3e-41 140.0 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF4972 PF16342.5 EPE25118.1 - 0.15 11.8 0.3 0.63 9.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) Peptidase_C48 PF02902.19 EPE25119.1 - 3.3e-33 115.4 0.0 1.6e-32 113.1 0.0 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Myosin_tail_1 PF01576.19 EPE25120.1 - 0.00082 17.3 10.0 0.00082 17.3 10.0 2.4 1 1 1 2 2 2 2 Myosin tail TPR_18 PF13512.6 EPE25120.1 - 0.0088 16.2 0.5 0.037 14.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DehI PF10778.9 EPE25120.1 - 0.14 12.3 0.5 0.66 10.1 0.1 2.3 2 0 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI Pilin_PilX PF11530.8 EPE25120.1 - 0.3 11.0 4.1 33 4.4 0.0 3.6 2 2 1 4 4 4 0 Minor type IV pilin, PilX PIN_9 PF18477.1 EPE25120.1 - 1.7 9.0 12.6 1.3 9.4 3.2 2.9 2 0 0 2 2 2 0 PIN like domain CEP63 PF17045.5 EPE25120.1 - 5.2 6.9 45.6 1.1 9.1 22.9 3.0 2 1 1 3 3 3 0 Centrosomal protein of 63 kDa Baculo_PEP_C PF04513.12 EPE25120.1 - 6.6 6.8 9.0 9.1 6.3 0.0 3.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cupin_1 PF00190.22 EPE25122.1 - 7.8e-31 106.7 0.3 7.5e-15 54.8 0.2 2.4 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EPE25122.1 - 4.3e-21 74.4 1.2 1.6e-11 43.8 0.3 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EPE25122.1 - 2.3e-07 30.4 0.1 0.0011 18.6 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EPE25122.1 - 6.4e-05 22.9 0.1 0.21 11.5 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.7 EPE25122.1 - 0.011 15.5 0.0 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Cupin NAD_binding_8 PF13450.6 EPE25123.1 - 3.5e-13 49.6 0.1 1.2e-12 47.9 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EPE25123.1 - 1.8e-09 37.4 0.0 4.6e-07 29.5 0.0 2.9 2 2 1 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EPE25123.1 - 2.7e-05 23.4 0.5 3.8e-05 23.0 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EPE25123.1 - 3.5e-05 23.4 0.5 8.6e-05 22.1 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 EPE25123.1 - 0.00031 20.4 0.9 0.00061 19.5 0.9 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EPE25123.1 - 0.00044 19.1 0.4 0.00086 18.1 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EPE25123.1 - 0.0012 18.1 0.8 0.0025 17.1 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE25123.1 - 0.0044 17.5 0.1 0.013 16.0 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EPE25123.1 - 0.0084 15.0 0.1 0.013 14.4 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase GMC_oxred_N PF00732.19 EPE25123.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase Thi4 PF01946.17 EPE25123.1 - 0.013 14.7 0.1 0.024 13.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 EPE25123.1 - 0.028 13.7 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPE25123.1 - 0.072 12.2 0.0 0.65 9.1 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EPE25123.1 - 0.12 11.5 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EPE25123.1 - 0.13 12.2 0.4 0.31 11.0 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Homeodomain PF00046.29 EPE25126.1 - 1.8e-09 37.3 1.2 7.6e-09 35.3 1.2 2.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EPE25126.1 - 0.0052 16.7 0.1 0.014 15.3 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 EPE25126.1 - 0.062 12.8 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez NMU PF02070.15 EPE25126.1 - 0.097 12.6 0.3 32 4.5 0.0 3.7 3 0 0 3 3 3 0 Neuromedin U Glycogen_syn PF05693.13 EPE25127.1 - 0 1162.8 0.0 0 1162.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 EPE25127.1 - 1.6e-06 28.2 0.1 7.9e-05 22.7 0.2 2.5 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EPE25127.1 - 5.1e-05 22.9 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EPE25127.1 - 7.1e-05 23.3 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 EPE25127.1 - 8.8e-05 22.9 0.0 0.21 12.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 EF-hand_1 PF00036.32 EPE25128.1 - 0.13 11.9 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 EF hand Glyco_hydro_3_C PF01915.22 EPE25129.1 - 1.8e-41 142.3 0.0 4.1e-41 141.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE25129.1 - 1.6e-32 113.2 0.0 8.1e-18 64.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE25129.1 - 5.2e-23 80.9 0.4 9.9e-23 80.0 0.4 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Big_2 PF02368.18 EPE25129.1 - 0.3 11.0 3.3 1.4 8.9 1.5 2.9 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 2) AAA-ATPase_like PF09820.9 EPE25130.1 - 0.14 11.6 0.1 0.18 11.2 0.1 1.1 1 0 0 1 1 1 0 Predicted AAA-ATPase DUF971 PF06155.12 EPE25130.1 - 0.16 12.6 0.5 0.37 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF971) Apolipoprotein PF01442.18 EPE25131.1 - 5.3e-07 29.7 145.6 0.00031 20.7 8.1 14.8 2 2 12 14 14 14 7 Apolipoprotein A1/A4/E domain Spc7 PF08317.11 EPE25131.1 - 0.0014 17.5 1.4 0.0014 17.5 1.4 14.9 1 1 14 17 17 17 8 Spc7 kinetochore protein Ribosomal_S6 PF01250.17 EPE25131.1 - 0.026 14.8 2.3 14 6.0 0.0 6.5 4 0 0 4 4 4 0 Ribosomal protein S6 FliG_M PF14841.6 EPE25131.1 - 0.027 14.7 13.0 0.61 10.4 0.2 6.6 5 0 0 5 5 5 0 FliG middle domain DUF1128 PF06569.11 EPE25131.1 - 0.06 13.3 3.6 2.3 8.2 0.2 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1128) Flg_bb_rod PF00460.20 EPE25131.1 - 1.4 8.9 4.1 1 9.4 0.3 2.9 2 0 0 2 2 2 0 Flagella basal body rod protein BET PF17035.5 EPE25133.1 - 0.091 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Med3 PF11593.8 EPE25134.1 - 0.53 9.4 2.1 0.71 9.0 2.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Usp PF00582.26 EPE25134.1 - 1 9.9 5.0 0.23 12.0 0.8 1.9 2 1 0 2 2 2 0 Universal stress protein family Cyclin PF08613.11 EPE25136.1 - 3.7e-08 33.9 0.0 5.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EPE25136.1 - 0.0079 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain CRC_subunit PF08624.10 EPE25137.1 - 7.8e-55 185.0 0.0 1.1e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit NAM-associated PF14303.6 EPE25137.1 - 3.4 8.4 6.5 5.9 7.6 6.5 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain FoP_duplication PF13865.6 EPE25137.1 - 6.4 7.4 9.2 20 5.8 9.2 1.8 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Pkinase PF00069.25 EPE25138.1 - 1.1e-66 224.9 0.0 1.5e-66 224.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE25138.1 - 9e-31 107.1 0.0 1.2e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EPE25138.1 - 3.3e-13 50.1 0.1 1.8e-12 47.8 0.1 2.4 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 EPE25138.1 - 3.8e-09 36.8 0.0 7.2e-07 29.4 0.0 2.6 2 0 0 2 2 2 1 C2 domain Kinase-like PF14531.6 EPE25138.1 - 8.7e-09 35.1 0.1 2.3e-08 33.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EPE25138.1 - 0.00083 18.4 0.2 0.0018 17.3 0.2 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EPE25138.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EPE25138.1 - 0.03 14.0 0.4 1.7 8.2 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Adeno_E3_15_3 PF03307.14 EPE25138.1 - 0.05 13.6 0.1 0.096 12.6 0.1 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region Kdo PF06293.14 EPE25138.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_5 PF13857.6 EPE25142.1 - 8.8e-16 57.8 0.0 1.4e-06 28.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE25142.1 - 1.4e-15 57.7 0.0 2e-06 28.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE25142.1 - 2.3e-12 47.2 0.0 2.3e-05 24.8 0.0 4.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EPE25142.1 - 3.4e-09 36.8 0.2 2.9e-06 27.5 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EPE25142.1 - 4.3e-09 35.9 0.0 0.0002 21.5 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat NACHT PF05729.12 EPE25142.1 - 4.1e-06 26.8 0.1 4.5e-05 23.4 0.0 2.8 3 0 0 3 3 3 1 NACHT domain Helo_like_N PF17111.5 EPE25142.1 - 7.5e-06 25.4 0.2 2e-05 24.0 0.2 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 EPE25142.1 - 0.0029 17.9 0.0 0.021 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_assoc_C PF09821.9 EPE25142.1 - 0.072 13.6 1.0 0.16 12.5 0.1 2.1 2 0 0 2 2 1 0 C-terminal AAA-associated domain DUF1993 PF09351.10 EPE25142.1 - 0.12 12.5 0.1 0.94 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) LANC_like PF05147.13 EPE25142.1 - 0.18 10.4 0.3 0.34 9.4 0.3 1.5 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Inhibitor_I78 PF11720.8 EPE25143.1 - 1.2e-10 41.2 0.0 1.7e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 EPE25143.1 - 0.00033 21.3 0.0 0.0004 21.0 0.0 1.2 1 0 0 1 1 1 1 Potato inhibitor I family FTP PF07504.13 EPE25143.1 - 0.027 14.3 0.2 0.04 13.7 0.2 1.3 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif CYYR1 PF10873.8 EPE25144.1 - 1.4 9.4 8.2 0.28 11.6 2.6 2.1 1 1 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 SNARE PF05739.19 EPE25145.1 - 2.3e-13 49.9 0.1 6.4e-13 48.5 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 EPE25145.1 - 8.3e-10 37.6 0.7 3e-09 35.9 0.7 2.0 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 EPE25145.1 - 7.7e-05 22.9 0.4 0.13 12.6 0.1 3.2 3 0 0 3 3 3 2 Uncharacterized conserved protein Syntaxin PF00804.25 EPE25145.1 - 0.0066 16.1 0.3 0.0066 16.1 0.3 3.2 2 1 0 3 3 3 1 Syntaxin Syntaxin-18_N PF10496.9 EPE25145.1 - 0.0082 16.4 0.9 0.084 13.1 0.0 2.7 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus Prominin PF05478.11 EPE25145.1 - 0.024 12.6 1.2 1.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Prominin TRPM_tetra PF16519.5 EPE25145.1 - 0.16 12.1 0.3 0.16 12.1 0.3 3.4 4 0 0 4 4 4 0 Tetramerisation domain of TRPM NPV_P10 PF05531.12 EPE25145.1 - 0.28 11.7 7.8 5.7 7.5 0.1 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein HsbA PF12296.8 EPE25145.1 - 0.29 11.5 3.2 1.3 9.5 1.2 2.5 2 0 0 2 2 2 0 Hydrophobic surface binding protein A DUF4988 PF16378.5 EPE25145.1 - 0.4 10.3 4.3 5.3 6.7 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function BLOC1_2 PF10046.9 EPE25145.1 - 0.67 10.3 3.2 6.6 7.1 0.0 3.5 4 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MCPsignal PF00015.21 EPE25145.1 - 1.2 8.9 8.8 0.26 11.1 0.6 2.9 3 1 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SF-assemblin PF06705.11 EPE25145.1 - 1.3 8.3 9.0 0.19 11.0 1.1 2.7 3 0 0 3 3 3 0 SF-assemblin/beta giardin HET PF06985.11 EPE25147.1 - 2.3e-31 109.1 0.5 5.5e-31 107.9 0.5 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PRK PF00485.18 EPE25148.1 - 7.2e-05 22.6 0.0 0.0001 22.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CbtA_toxin PF06755.12 EPE25148.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.5 1 1 0 1 1 1 0 CbtA_toxin of type IV toxin-antitoxin system T2SSE PF00437.20 EPE25148.1 - 0.032 13.3 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 EPE25148.1 - 0.063 13.4 0.3 6.6 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain CoaE PF01121.20 EPE25148.1 - 0.087 12.5 0.1 13 5.4 0.1 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_29 PF13555.6 EPE25148.1 - 0.087 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EPE25148.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sugar_tr PF00083.24 EPE25149.1 - 3.1e-43 148.3 14.0 3.7e-43 148.0 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE25149.1 - 4.4e-09 35.7 10.7 5.9e-09 35.3 10.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 EPE25150.1 - 1.3e-28 99.7 0.1 1.3e-28 99.7 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ribonuc_L-PSP PF01042.21 EPE25151.1 - 1.5e-22 79.9 0.0 1.8e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peripla_BP_6 PF13458.6 EPE25151.1 - 0.022 14.5 0.1 0.026 14.2 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Nitr_red_alph_N PF14710.6 EPE25151.1 - 0.082 13.4 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 Respiratory nitrate reductase alpha N-terminal HET PF06985.11 EPE25152.1 - 7.6e-27 94.5 0.8 4.1e-26 92.1 0.8 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) YL1 PF05764.13 EPE25153.1 - 0.34 11.0 5.2 0.14 12.2 2.5 1.9 2 0 0 2 2 2 0 YL1 nuclear protein Asp PF00026.23 EPE25154.1 - 1.3e-59 202.2 0.1 2.1e-59 201.5 0.1 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPE25154.1 - 2.2e-09 37.8 1.4 1.7e-06 28.4 1.4 2.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EPE25154.1 - 0.041 14.4 0.3 3.6 8.2 0.0 3.6 4 1 0 4 4 4 0 gag-polyprotein putative aspartyl protease Abhydrolase_2 PF02230.16 EPE25155.1 - 2.6e-39 135.3 0.0 1.5e-37 129.5 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EPE25155.1 - 5.2e-05 23.0 0.0 7.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EPE25155.1 - 0.0011 19.6 0.0 0.0018 19.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE25155.1 - 0.078 12.6 0.0 0.26 10.9 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EPE25155.1 - 0.094 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0565 PF10561.9 EPE25155.1 - 0.14 11.3 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF3433 PF11915.8 EPE25157.1 - 2.8e-23 82.2 3.4 2.8e-23 82.2 3.4 4.0 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Acetyltransf_1 PF00583.25 EPE25158.1 - 7.7e-08 32.6 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE25158.1 - 7.4e-07 29.2 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE25158.1 - 1.6e-06 28.4 0.0 3.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pentapeptide_4 PF13599.6 EPE25158.1 - 0.022 14.9 1.4 0.039 14.1 1.4 1.3 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) Acetyltransf_9 PF13527.7 EPE25158.1 - 0.077 13.1 0.2 0.51 10.4 0.1 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE25158.1 - 0.2 11.6 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DUF3328 PF11807.8 EPE25159.1 - 8.4e-19 68.2 0.1 1e-18 67.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) AA_permease_2 PF13520.6 EPE25162.1 - 2.4e-48 165.0 59.0 3e-48 164.7 59.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE25162.1 - 4.9e-21 74.9 39.6 4.9e-21 74.9 39.6 1.8 2 0 0 2 2 2 1 Amino acid permease EGF_3 PF12947.7 EPE25163.1 - 0.036 14.3 3.4 0.086 13.1 3.4 1.7 1 0 0 1 1 1 0 EGF domain EGF_CA PF07645.15 EPE25163.1 - 0.084 13.1 2.5 0.29 11.4 2.5 1.9 1 0 0 1 1 1 0 Calcium-binding EGF domain SCO1-SenC PF02630.14 EPE25164.1 - 5.1e-47 159.2 0.0 7.1e-47 158.7 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EPE25164.1 - 0.0034 17.3 0.0 0.016 15.2 0.0 1.9 2 1 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 EPE25164.1 - 0.16 11.6 0.0 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Redoxin Glyco_hydro_92 PF07971.12 EPE25166.1 - 3.5e-137 458.1 1.2 4.2e-137 457.8 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EPE25166.1 - 3.9e-46 157.9 3.0 6e-46 157.3 3.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Glyco_transf_25 PF01755.17 EPE25167.1 - 4e-10 39.9 0.0 6.7e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Esterase_phd PF10503.9 EPE25168.1 - 3e-21 75.9 0.3 4.7e-21 75.3 0.3 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EPE25168.1 - 4.5e-14 52.4 0.9 6.5e-14 51.9 0.9 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EPE25168.1 - 0.0014 18.4 0.2 0.0024 17.6 0.2 1.3 1 1 0 1 1 1 1 Putative esterase COesterase PF00135.28 EPE25168.1 - 0.022 13.6 0.2 0.068 12.0 0.0 1.7 2 0 0 2 2 2 0 Carboxylesterase family Zn_clus PF00172.18 EPE25169.1 - 8.1e-05 22.7 7.6 0.0002 21.4 7.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 EPE25170.1 - 1.6e-17 64.1 0.0 1e-09 38.9 0.0 2.6 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) Glyco_hydro_18 PF00704.28 EPE25170.1 - 2.1e-13 50.7 0.0 3.2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AAA_16 PF13191.6 EPE25170.1 - 0.005 17.2 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EPE25170.1 - 0.0096 15.9 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 EPE25170.1 - 0.059 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 EPE25170.1 - 0.067 12.9 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EPE25170.1 - 0.069 13.7 0.1 0.26 11.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 EPE25170.1 - 0.091 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EPE25170.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4710 PF15828.5 EPE25170.1 - 0.18 11.9 1.1 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) MIP PF00230.20 EPE25174.1 - 1.4e-43 149.2 11.4 1.9e-43 148.8 11.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein Rad60-SLD PF11976.8 EPE25175.1 - 6.5e-19 67.5 0.1 8e-19 67.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EPE25175.1 - 7.2e-09 35.3 0.0 9e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family HET PF06985.11 EPE25177.1 - 1.8e-11 44.6 10.1 8.9e-09 35.9 10.1 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.23 EPE25178.1 - 3.2e-25 88.5 2.2 5.2e-25 87.8 2.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE25178.1 - 1.4e-11 44.3 0.0 3.9e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like NACHT PF05729.12 EPE25179.1 - 1.9e-08 34.4 0.0 7.1e-08 32.6 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EPE25179.1 - 0.022 15.0 0.0 0.11 12.8 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EPE25179.1 - 0.045 13.5 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EPE25179.1 - 0.045 14.3 0.0 0.21 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EPE25179.1 - 0.045 13.5 0.0 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EPE25179.1 - 0.056 14.0 0.0 0.2 12.2 0.0 1.9 1 0 0 1 1 1 0 ABC transporter DUF3474 PF11960.8 EPE25179.1 - 0.087 13.0 0.0 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) AAA_16 PF13191.6 EPE25179.1 - 0.099 13.0 0.0 0.41 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EPE25179.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 EPE25179.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AA_permease PF00324.21 EPE25181.1 - 5.6e-137 457.2 44.2 6.5e-137 457.0 44.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE25181.1 - 1.5e-31 109.7 47.3 2e-31 109.3 47.3 1.1 1 0 0 1 1 1 1 Amino acid permease Pectate_lyase_3 PF12708.7 EPE25182.1 - 6e-98 326.9 13.5 2.6e-82 275.8 7.4 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EPE25182.1 - 2.8e-08 33.3 0.8 0.00075 19.1 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Ras PF00071.22 EPE25184.1 - 1.3e-55 187.4 0.0 1.5e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE25184.1 - 1.1e-21 77.2 0.0 1.7e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE25184.1 - 7.3e-10 38.6 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EPE25184.1 - 0.0011 18.2 0.0 0.0015 17.8 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 EPE25184.1 - 0.0016 17.9 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EPE25184.1 - 0.0019 17.6 0.0 0.0025 17.2 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EPE25184.1 - 0.015 15.3 0.0 0.027 14.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EPE25184.1 - 0.039 14.5 0.0 0.068 13.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter IU_nuc_hydro PF01156.19 EPE25185.1 - 3e-10 40.2 0.0 3.7e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase V-ATPase_H_C PF11698.8 EPE25185.1 - 0.072 13.2 0.1 11 6.1 0.0 2.4 2 0 0 2 2 2 0 V-ATPase subunit H PepX_N PF09168.10 EPE25185.1 - 0.16 12.4 0.1 0.32 11.4 0.1 1.5 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal CWC25 PF12542.8 EPE25186.1 - 2.3e-26 92.7 0.7 2.3e-26 92.7 0.7 4.2 2 2 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 EPE25186.1 - 2.6e-14 53.1 7.2 2.6e-14 53.1 7.2 3.4 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR PCI PF01399.27 EPE25187.1 - 7.4e-19 68.2 0.5 2.1e-18 66.8 0.1 2.0 2 0 0 2 2 2 1 PCI domain TPR_7 PF13176.6 EPE25187.1 - 0.0016 18.3 0.4 0.24 11.5 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EPE25187.1 - 0.0049 16.9 0.7 0.058 13.5 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EPE25187.1 - 0.007 16.2 1.3 0.044 13.6 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EPE25187.1 - 0.042 13.5 0.6 0.14 11.9 0.1 2.2 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.6 EPE25187.1 - 0.045 14.0 0.1 1.7 9.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EPE25187.1 - 0.39 11.1 2.5 2.8 8.4 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_C65 PF10275.9 EPE25188.1 - 1.9e-69 233.9 0.0 2.6e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain BPL_LplA_LipB PF03099.19 EPE25189.1 - 2.8e-06 27.3 0.0 0.055 13.4 0.0 2.3 2 0 0 2 2 2 2 Biotin/lipoate A/B protein ligase family Erg28 PF03694.13 EPE25190.1 - 6.2e-34 116.7 1.6 8.5e-34 116.3 1.6 1.2 1 0 0 1 1 1 1 Erg28 like protein EOS1 PF12326.8 EPE25190.1 - 1.8 8.5 6.4 1.2 9.1 3.6 1.9 2 0 0 2 2 2 0 N-glycosylation protein 3Beta_HSD PF01073.19 EPE25191.1 - 9.8e-47 159.3 0.0 1.2e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPE25191.1 - 1.3e-24 87.0 0.0 2e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE25191.1 - 1e-11 44.8 0.3 2.9e-09 36.8 0.1 2.6 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPE25191.1 - 2e-11 43.6 0.0 2.8e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 EPE25191.1 - 1.7e-07 30.7 0.1 2e-06 27.2 0.1 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EPE25191.1 - 8.1e-05 22.6 0.0 0.00015 21.7 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EPE25191.1 - 9.9e-05 21.6 0.0 0.00017 20.8 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EPE25191.1 - 0.0045 16.9 2.7 0.24 11.3 0.1 2.9 2 1 0 2 2 2 1 KR domain TPR_4 PF07721.14 EPE25191.1 - 0.18 12.6 0.3 0.44 11.3 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat SUR7 PF06687.12 EPE25192.1 - 2.5e-33 115.5 3.6 3e-33 115.2 3.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family Halogen_Hydrol PF10112.9 EPE25192.1 - 0.3 11.1 0.0 0.3 11.1 0.0 2.4 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Phage_holin_3_6 PF07332.11 EPE25192.1 - 0.36 10.9 10.0 0.088 12.9 1.8 2.5 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Putative_PNPOx PF01243.20 EPE25194.1 - 1.9e-13 50.4 0.0 1.7e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EPE25194.1 - 0.0002 21.3 0.0 0.016 15.2 0.0 2.2 1 1 1 2 2 2 2 Pyridoxamine 5'-phosphate oxidase DUF2002 PF09400.10 EPE25194.1 - 0.037 14.0 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) TRM PF02005.16 EPE25195.1 - 1.4e-108 363.4 0.0 4e-93 312.6 0.0 2.3 2 1 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EPE25195.1 - 0.0082 15.9 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Met-10+ like-protein Mnd1 PF03962.15 EPE25196.1 - 0.12 12.6 0.1 0.32 11.3 0.1 1.6 1 0 0 1 1 1 0 Mnd1 HTH domain RAP1 PF07218.11 EPE25196.1 - 2.9 6.1 10.7 4 5.6 10.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) YbgT_YccB PF08173.11 EPE25197.1 - 1 9.6 6.9 1.5 9.0 0.4 3.2 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Popeye PF04831.13 EPE25197.1 - 2.2 8.5 7.0 0.94 9.6 3.9 2.0 1 1 0 2 2 2 0 Popeye protein conserved region Tyrosinase PF00264.20 EPE25198.1 - 4.4e-55 187.4 2.2 5.7e-55 187.0 2.2 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase THOC2_N PF16134.5 EPE25199.1 - 3.8e-242 805.5 0.0 5.6e-242 804.9 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EPE25199.1 - 4.2e-86 288.9 0.0 6.3e-86 288.3 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EPE25199.1 - 3.1e-26 91.2 0.1 3.4e-25 87.9 0.0 2.3 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Abhydrolase_1 PF00561.20 EPE25200.1 - 1.7e-48 165.6 0.0 2.8e-48 164.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE25200.1 - 6.4e-05 23.7 3.5 0.00031 21.4 3.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EPE25200.1 - 0.019 15.1 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Say1_Mug180 PF10340.9 EPE25200.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase ERG4_ERG24 PF01222.17 EPE25201.1 - 6.2e-91 305.3 13.8 7.3e-91 305.1 13.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EPE25201.1 - 0.00093 18.8 0.3 0.0025 17.4 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NAD_binding_10 PF13460.6 EPE25202.1 - 7.5e-15 55.3 0.0 9.1e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EPE25202.1 - 1.1e-05 25.8 0.0 1.6e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 EPE25202.1 - 8.7e-05 22.2 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EPE25202.1 - 0.0007 19.1 0.0 0.00098 18.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE25202.1 - 0.0013 17.8 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EPE25202.1 - 0.0076 16.5 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 EPE25202.1 - 0.03 13.5 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 EPE25202.1 - 0.051 12.7 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EPE25202.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Aldolase_II PF00596.21 EPE25203.1 - 1.1e-41 142.8 0.2 1.4e-41 142.4 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain CDP-OH_P_transf PF01066.21 EPE25204.1 - 4e-17 62.7 0.1 4e-17 62.7 0.1 3.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF5313 PF17240.2 EPE25204.1 - 0.41 11.1 1.9 11 6.4 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5313) Adaptin_N PF01602.20 EPE25205.1 - 4.7e-106 355.4 0.0 6.4e-106 355.0 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EPE25205.1 - 1.1e-57 194.4 6.8 2.1e-57 193.5 6.8 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EPE25205.1 - 8.8e-35 119.3 0.1 2.2e-34 118.0 0.1 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EPE25205.1 - 3e-14 53.2 1.1 1.3e-10 41.5 0.0 4.5 3 1 2 5 5 5 1 HEAT repeats Cnd1 PF12717.7 EPE25205.1 - 2.5e-05 24.4 5.1 1.5 8.9 0.0 4.9 4 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EPE25205.1 - 0.0061 16.2 1.8 0.12 11.9 0.0 3.0 3 0 0 3 3 3 1 CLASP N terminal Coatomer_b_Cpla PF14806.6 EPE25205.1 - 0.013 15.5 0.0 0.038 14.0 0.0 1.8 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform HEAT_PBS PF03130.16 EPE25205.1 - 0.053 14.2 0.3 1.4 9.8 0.0 3.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 EPE25205.1 - 0.066 13.7 0.3 0.35 11.4 0.3 2.3 1 0 0 1 1 1 0 HEAT-like repeat HEAT PF02985.22 EPE25205.1 - 0.095 13.0 7.6 2.7 8.5 0.2 4.8 5 0 0 5 5 5 0 HEAT repeat bZIP_1 PF00170.21 EPE25206.1 - 8.9e-09 35.3 13.5 1.3e-08 34.8 13.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 EPE25206.1 - 0.0011 18.8 12.6 0.0038 17.0 0.0 2.4 1 1 1 2 2 2 1 Transcription factor PAP1 SHE3 PF17078.5 EPE25206.1 - 0.0049 16.6 5.6 0.007 16.1 5.6 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 EPE25206.1 - 0.0071 16.8 9.9 0.012 16.1 9.9 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor GRIM-19 PF06212.12 EPE25206.1 - 0.034 14.1 0.2 0.067 13.1 0.2 1.4 1 0 0 1 1 1 0 GRIM-19 protein Mobilization_B PF17511.2 EPE25206.1 - 0.067 13.6 2.0 0.13 12.6 2.0 1.4 1 0 0 1 1 1 0 Mobilization protein B YabA PF06156.13 EPE25206.1 - 0.15 12.7 2.9 0.27 11.9 2.9 1.4 1 0 0 1 1 1 0 Initiation control protein YabA MCC-bdg_PDZ PF10506.9 EPE25206.1 - 0.18 11.8 5.9 0.27 11.3 5.1 1.7 1 1 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome V_ATPase_I PF01496.19 EPE25206.1 - 0.2 9.5 3.7 0.25 9.2 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GvpL_GvpF PF06386.11 EPE25206.1 - 0.32 10.9 5.9 0.45 10.4 5.9 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Pox_G5 PF04599.12 EPE25206.1 - 0.97 8.4 4.4 1.3 7.9 4.4 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein DUF2205 PF10224.9 EPE25206.1 - 1 9.4 6.0 2.2 8.3 6.0 1.6 1 1 0 1 1 1 0 Short coiled-coil protein UPF0242 PF06785.11 EPE25206.1 - 1.3 9.1 7.8 1.9 8.5 7.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5383 PF17355.2 EPE25206.1 - 2.1 8.8 8.7 3.2 8.2 8.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5383) bZIP_2 PF07716.15 EPE25206.1 - 3.8 7.7 17.9 10 6.3 17.0 2.0 1 1 1 2 2 2 0 Basic region leucine zipper RNR_inhib PF08591.10 EPE25207.1 - 4.8e-28 98.6 0.8 8.2e-28 97.8 0.1 1.7 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor Phosducin PF02114.16 EPE25208.1 - 7e-11 41.6 0.0 1.3e-10 40.7 0.0 1.4 1 1 0 1 1 1 1 Phosducin ADH_N PF08240.12 EPE25209.1 - 4.1e-28 97.4 0.8 8e-28 96.5 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE25209.1 - 2.1e-12 47.2 0.2 1e-10 41.7 0.2 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EPE25209.1 - 0.0074 15.8 0.1 0.4 10.1 0.0 2.8 2 1 1 3 3 3 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 EPE25209.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.18 EPE25211.1 - 1.7e-14 53.5 0.0 2.9e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GRA6 PF05084.13 EPE25212.1 - 0.066 13.2 0.4 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 Granule antigen protein (GRA6) DctQ PF04290.12 EPE25212.1 - 0.16 11.9 9.9 0.95 9.4 1.9 3.1 2 1 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Amastin PF07344.11 EPE25212.1 - 0.77 9.6 15.9 4.2 7.2 0.6 2.6 2 1 1 3 3 3 0 Amastin surface glycoprotein DUF1129 PF06570.11 EPE25212.1 - 7.1 6.1 9.0 0.58 9.6 3.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4064 PF13273.6 EPE25212.1 - 8.9 6.6 13.0 25 5.2 7.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) ERG4_ERG24 PF01222.17 EPE25213.1 - 2e-09 36.7 0.5 3.6e-09 35.9 0.5 1.4 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EPE25213.1 - 2.7e-09 36.9 0.0 3.7e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) MFS_1 PF07690.16 EPE25214.1 - 9.7e-31 107.0 35.6 9.7e-31 107.0 35.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE25214.1 - 2.4e-11 43.2 6.8 2.4e-11 43.2 6.8 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter Holin_BhlA PF10960.8 EPE25214.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 BhlA holin family PIRT PF15099.6 EPE25214.1 - 0.084 12.5 1.4 0.32 10.6 0.1 2.4 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family tRNA-synt_2 PF00152.20 EPE25215.1 - 1.6e-62 211.4 0.0 2e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EPE25215.1 - 1.2e-06 28.4 0.1 2.2e-05 24.3 0.1 2.3 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain BetR PF08667.10 EPE25215.1 - 0.027 14.5 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 BetR domain NARP1 PF12569.8 EPE25215.1 - 0.43 9.4 6.2 0.61 8.9 6.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Raptor_N PF14538.6 EPE25216.1 - 2.8e-63 212.3 0.0 5.7e-63 211.3 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EPE25216.1 - 0.00041 21.1 9.3 2.1 9.4 0.0 6.2 7 0 0 7 7 7 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 EPE25216.1 - 0.00045 20.2 0.0 3 7.9 0.0 3.3 1 1 2 3 3 3 3 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.9 EPE25216.1 - 0.0082 16.1 0.4 0.017 15.1 0.4 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Kelch_4 PF13418.6 EPE25218.1 - 6.8e-32 109.2 7.3 7.9e-06 25.8 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EPE25218.1 - 1.8e-31 107.4 3.9 2e-12 46.9 1.2 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_3 PF13415.6 EPE25218.1 - 1.6e-30 104.8 10.0 1.8e-07 31.3 0.2 5.9 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EPE25218.1 - 9.3e-29 98.9 6.2 5.8e-08 32.6 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 EPE25218.1 - 7e-28 96.0 4.6 4.2e-11 42.3 1.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EPE25218.1 - 1.6e-20 72.2 3.1 2.7e-08 33.4 0.5 6.4 6 0 0 6 6 6 4 Kelch motif Pkinase PF00069.25 EPE25219.1 - 7.6e-26 91.0 0.0 1e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE25219.1 - 2.3e-13 50.0 0.0 3.3e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPE25219.1 - 5.3e-09 35.4 0.0 1.2e-08 34.2 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EPE25219.1 - 0.00045 20.2 0.0 0.0028 17.6 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family DUF4596 PF15363.6 EPE25220.1 - 0.047 13.9 2.2 0.086 13.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) p450 PF00067.22 EPE25222.1 - 6.5e-53 180.1 0.0 8.7e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NMO PF03060.15 EPE25223.1 - 2.2e-32 112.8 6.1 4.9e-27 95.2 2.8 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EPE25223.1 - 2.1e-09 36.9 1.2 3.5e-09 36.2 1.2 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EPE25223.1 - 4.1e-07 29.3 1.2 1.3e-06 27.7 1.1 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EPE25223.1 - 2.6e-06 26.8 0.5 3.9e-06 26.3 0.5 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 EPE25223.1 - 0.047 13.0 0.3 0.069 12.4 0.3 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PTR2 PF00854.21 EPE25225.1 - 1.3e-79 267.8 12.9 1.7e-79 267.5 12.9 1.1 1 0 0 1 1 1 1 POT family UCH PF00443.29 EPE25227.1 - 1.9e-36 125.9 0.3 3.1e-31 108.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPE25227.1 - 2.7e-05 23.9 9.6 0.0038 16.9 5.0 3.3 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L9_N PF01281.19 EPE25228.1 - 2.3e-14 52.6 0.2 1e-13 50.6 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 EPE25228.1 - 0.11 13.0 0.1 0.42 11.1 0.1 1.9 1 1 0 1 1 1 0 Ribosomal protein L9, C-terminal domain F_bP_aldolase PF01116.20 EPE25229.1 - 1.5e-91 306.8 0.0 1.6e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Oxysterol_BP PF01237.18 EPE25230.1 - 3.4e-63 213.7 1.7 6.1e-56 189.9 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein zf-RING_UBOX PF13445.6 EPE25231.1 - 0.54 10.3 5.5 1.7 8.7 5.5 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C2HC5 PF06221.13 EPE25231.1 - 1.2 9.2 4.3 2.5 8.2 0.1 2.9 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type HUN PF08729.10 EPE25232.1 - 0.0064 16.5 0.4 0.014 15.4 0.4 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain ATG27 PF09451.10 EPE25232.1 - 0.17 11.7 0.1 0.29 10.9 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Ribosomal_S25 PF03297.15 EPE25233.1 - 0.22 11.8 0.1 19 5.5 0.1 2.4 2 0 0 2 2 2 0 S25 ribosomal protein DUF1700 PF08006.11 EPE25233.1 - 7.1 6.1 7.2 0.37 10.3 0.5 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1700) AA_permease_2 PF13520.6 EPE25235.1 - 3e-54 184.5 55.9 3.5e-54 184.3 55.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE25235.1 - 3e-13 49.2 48.5 4.2e-13 48.7 48.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3405 PF11885.8 EPE25237.1 - 1.2e-225 750.0 4.6 1.6e-225 749.6 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) RRM_1 PF00076.22 EPE25238.1 - 1.6e-11 43.9 0.2 2.3e-06 27.3 0.1 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPE25238.1 - 0.022 14.6 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif Rv2175c_C PF18367.1 EPE25238.1 - 0.081 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Rv2175c C-terminal domain of unknown function RRM_5 PF13893.6 EPE25238.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S49_N PF08496.10 EPE25238.1 - 6.9 6.7 10.6 0.19 11.8 0.6 2.5 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Cupin_2 PF07883.11 EPE25239.1 - 1.4e-08 34.3 0.1 2.1e-08 33.8 0.1 1.2 1 0 0 1 1 1 1 Cupin domain DUF4437 PF14499.6 EPE25239.1 - 0.021 13.9 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Cupin_1 PF00190.22 EPE25239.1 - 0.022 14.4 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_7 PF12973.7 EPE25239.1 - 0.026 14.4 0.1 0.052 13.5 0.1 1.6 1 1 0 1 1 1 0 ChrR Cupin-like domain PI-PLC-X PF00388.19 EPE25240.1 - 7.3e-10 38.6 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L10 PF00466.20 EPE25241.1 - 0.0053 16.9 0.0 0.044 13.9 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L10 Sec31 PF11549.8 EPE25241.1 - 0.0055 16.6 0.2 0.0055 16.6 0.2 1.7 2 0 0 2 2 2 1 Protein transport protein SEC31 Glycos_transf_3 PF00591.21 EPE25242.1 - 2.8e-60 204.0 0.0 4.2e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EPE25242.1 - 1.1e-13 50.8 0.0 2.1e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain 2-Hacid_dh_C PF02826.19 EPE25243.1 - 7.8e-52 175.2 0.0 1.8e-51 174.0 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPE25243.1 - 2.7e-20 72.4 0.0 3.3e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EPE25243.1 - 0.00055 20.1 0.2 0.00094 19.4 0.2 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.18 EPE25244.1 - 7.1e-09 35.6 10.8 1.1e-08 35.1 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2478 PF10649.9 EPE25244.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) Nefa_Nip30_N PF10187.9 EPE25245.1 - 1.5e-33 115.2 6.5 3.5e-33 114.1 6.5 1.6 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Flagellar_rod PF05149.12 EPE25245.1 - 0.11 12.0 10.3 0.17 11.3 10.3 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein Baculo_F PF12259.8 EPE25245.1 - 0.35 9.3 1.1 0.45 9.0 1.1 1.1 1 0 0 1 1 1 0 Baculovirus F protein Aldo_ket_red PF00248.21 EPE25246.1 - 4.7e-39 134.3 0.0 4e-37 128.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family HIT PF01230.23 EPE25247.1 - 1.4e-18 67.4 0.0 2.3e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EPE25247.1 - 0.00059 20.3 0.0 0.00095 19.6 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EPE25247.1 - 0.0038 17.1 0.3 0.011 15.7 0.3 1.9 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 UPF0020 PF01170.18 EPE25248.1 - 1.4e-07 31.4 0.0 1.1e-05 25.2 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 DNA_ligase_IV PF11411.8 EPE25248.1 - 0.033 14.3 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 DNA ligase IV Ribonuc_P_40 PF08584.11 EPE25249.1 - 1.2e-21 77.3 0.0 1.2e-21 77.2 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Ank_2 PF12796.7 EPE25250.1 - 6.2e-12 46.0 3.5 3.2e-06 27.6 0.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE25250.1 - 8.5e-12 45.1 0.1 6.7e-10 39.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPE25250.1 - 1.2e-07 32.1 0.0 2.3e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE25250.1 - 2e-05 24.6 0.1 0.00013 22.1 0.3 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EPE25250.1 - 0.013 15.9 1.9 0.04 14.4 0.2 2.5 3 0 0 3 3 3 0 Ankyrin repeat Peptidase_M17_N PF02789.17 EPE25250.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain tRNA_lig_CPD PF08302.11 EPE25251.1 - 1.2e-86 290.3 0.0 1.6e-86 289.9 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 EPE25251.1 - 6.4e-86 287.7 0.0 1.1e-85 287.0 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 EPE25251.1 - 6.1e-55 185.9 0.0 1.3e-54 184.8 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain RNA_ligase PF09414.10 EPE25251.1 - 0.015 15.6 0.0 0.052 13.9 0.0 1.9 2 0 0 2 2 2 0 RNA ligase Fe_hyd_lg_C PF02906.14 EPE25254.1 - 4.8e-53 180.3 0.0 1.1e-52 179.2 0.0 1.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Aldo_ket_red PF00248.21 EPE25256.1 - 2.7e-66 223.8 0.0 3e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LPD7 PF18821.1 EPE25256.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 7 zf-C2H2 PF00096.26 EPE25257.1 - 1.4e-06 28.4 0.2 1.4e-06 28.4 0.2 1.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 EPE25257.1 - 3.5e-05 24.4 3.8 0.057 14.1 0.2 2.7 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EPE25257.1 - 0.0036 18.0 0.2 0.0036 18.0 0.2 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPE25257.1 - 0.025 15.0 2.6 0.28 11.7 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 EPE25257.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger SOGA PF11365.8 EPE25257.1 - 0.074 14.2 2.0 0.081 14.1 0.4 1.9 2 0 0 2 2 2 0 Protein SOGA zf-C2H2_11 PF16622.5 EPE25257.1 - 0.22 11.3 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type DUF4692 PF15763.5 EPE25257.1 - 0.68 10.4 5.6 0.98 9.9 0.5 2.2 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) zf-Di19 PF05605.12 EPE25257.1 - 0.89 9.9 2.7 3.9 7.8 2.7 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Torus PF16131.5 EPE25258.1 - 0.00057 20.6 0.1 0.0011 19.7 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 EPE25258.1 - 0.0035 17.1 9.6 0.0054 16.5 9.6 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EPE25258.1 - 8.2 6.6 14.9 15 5.8 14.9 1.4 1 0 0 1 1 1 0 Zinc finger domain CAP_GLY PF01302.25 EPE25259.1 - 5.9e-17 61.4 0.2 1.7e-16 59.9 0.1 1.8 2 0 0 2 2 2 1 CAP-Gly domain LRR_4 PF12799.7 EPE25259.1 - 8.3e-13 48.3 15.6 0.0037 17.6 4.0 4.7 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EPE25259.1 - 1.5e-10 40.7 11.5 0.00015 21.4 1.3 5.3 4 2 1 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 EPE25259.1 - 6.3e-06 25.8 2.0 0.15 11.5 0.4 3.5 2 1 0 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EPE25259.1 - 0.00068 19.5 9.4 17 5.8 0.1 6.6 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 EPE25259.1 - 1.3 9.8 10.7 1.8e+02 3.3 0.0 6.3 6 1 0 6 6 6 0 Leucine Rich Repeat SF3A2 PF16835.5 EPE25260.1 - 3.5e-38 129.9 0.1 5.1e-38 129.3 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EPE25260.1 - 1.1e-05 25.6 0.5 2.1e-05 24.7 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 EPE25260.1 - 0.063 12.8 1.5 0.11 12.0 1.5 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.25 EPE25261.1 - 4.8e-59 199.9 0.0 6.2e-58 196.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE25261.1 - 5.8e-27 94.6 0.1 5.4e-21 75.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EPE25261.1 - 7e-05 21.9 0.1 0.0001 21.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EPE25261.1 - 0.00082 19.4 0.1 0.11 12.3 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EPE25261.1 - 0.0011 18.4 0.1 0.0028 17.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPE25261.1 - 0.0012 18.2 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EPE25261.1 - 0.033 13.2 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EPE25261.1 - 0.42 10.2 0.0 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Atx10homo_assoc PF09759.9 EPE25263.1 - 4.3e-14 52.3 0.3 1.3e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DZR PF12773.7 EPE25263.1 - 0.033 14.2 0.5 0.065 13.3 0.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EPE25263.1 - 0.06 12.8 2.6 0.16 11.4 2.6 1.8 1 0 0 1 1 1 0 zinc-ribbon domain YopE PF03545.13 EPE25263.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) DNA_pol_phi PF04931.13 EPE25263.1 - 7.4 4.5 10.4 12 3.9 10.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi RIFIN PF02009.16 EPE25264.1 - 0.055 13.4 0.4 0.065 13.1 0.4 1.1 1 0 0 1 1 1 0 Rifin SOG2 PF10428.9 EPE25264.1 - 2.1 7.4 11.9 2.5 7.2 11.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF829 PF05705.14 EPE25265.1 - 5e-36 124.8 0.1 5.8e-36 124.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) p450 PF00067.22 EPE25266.1 - 7.3e-61 206.3 0.0 9.6e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_2 PF00152.20 EPE25267.1 - 6.4e-79 265.3 1.3 9.2e-79 264.8 1.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EPE25267.1 - 5.6e-12 45.5 0.4 2.1e-11 43.6 0.1 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EPE25267.1 - 2.1e-05 24.1 1.1 0.02 14.4 0.1 2.5 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) COX15-CtaA PF02628.15 EPE25268.1 - 2.3e-112 375.3 9.2 2.8e-112 375.0 9.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF5389 PF17364.2 EPE25268.1 - 0.6 10.2 3.7 11 6.2 0.2 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5389) UCH PF00443.29 EPE25270.1 - 4.1e-30 105.1 0.0 6.7e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPE25270.1 - 3.5e-07 30.1 0.0 3.2e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EPE25270.1 - 0.1 13.1 0.0 0.31 11.6 0.0 1.9 1 0 0 1 1 1 0 Rhodanese-like domain IKKbetaNEMObind PF12179.8 EPE25270.1 - 0.23 11.5 0.6 6.7 6.8 0.0 2.6 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain VHS PF00790.19 EPE25271.1 - 1e-39 135.6 1.3 5.5e-39 133.2 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 EPE25271.1 - 1e-15 57.6 1.1 2e-15 56.7 1.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EPE25271.1 - 4e-05 23.2 12.7 0.0036 17.1 1.7 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 EPE25271.1 - 0.00015 22.0 0.0 0.00042 20.6 0.0 1.9 1 0 0 1 1 1 1 GAT domain C1_1 PF00130.22 EPE25271.1 - 0.047 13.6 2.1 0.087 12.7 2.1 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE_2 PF02318.16 EPE25271.1 - 0.16 12.2 0.8 0.4 10.9 0.8 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger GTP_EFTU PF00009.27 EPE25272.1 - 3.6e-48 163.7 0.0 6e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 EPE25272.1 - 1.9e-23 82.6 0.4 3.8e-23 81.6 0.4 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.25 EPE25272.1 - 3.6e-09 36.9 0.0 8.2e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EPE25272.1 - 1.1e-08 35.1 0.0 0.00012 22.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 EPE25272.1 - 9.7e-07 29.1 0.0 2.4e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Roc PF08477.13 EPE25272.1 - 0.002 18.3 0.0 0.45 10.7 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EPE25272.1 - 0.021 14.3 0.0 1.5 8.2 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF4640 PF15480.6 EPE25272.1 - 0.3 10.8 3.0 6.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4640) TssN PF17555.2 EPE25273.1 - 0.034 13.5 8.4 0.043 13.2 8.4 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF1282 PF06930.12 EPE25273.1 - 0.53 10.0 8.6 0.55 10.0 7.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) YrhC PF14143.6 EPE25273.1 - 1.4 9.1 8.9 0.064 13.4 1.1 2.4 2 2 0 2 2 2 0 YrhC-like protein GLTT PF01744.20 EPE25274.1 - 0.11 12.3 1.6 0.23 11.3 1.6 1.5 1 0 0 1 1 1 0 GLTT repeat (6 copies) VCBS PF13517.6 EPE25275.1 - 6.8e-27 93.8 35.4 9.3e-09 35.8 4.3 5.3 2 1 4 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 EPE25275.1 - 1.7e-19 70.9 0.4 4.2e-19 69.6 0.4 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE25275.1 - 1.1e-10 41.8 0.0 1.7e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Dockerin_1 PF00404.18 EPE25275.1 - 6.8e-08 32.6 2.4 5.8 7.2 0.0 5.6 5 0 0 5 5 5 2 Dockerin type I domain Aspzincin_M35 PF14521.6 EPE25275.1 - 8e-07 29.7 0.1 6.1e-06 26.9 0.1 2.4 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Lipase_GDSL_3 PF14606.6 EPE25275.1 - 6.5e-06 26.4 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.23 EPE25275.1 - 2.8e-05 24.1 14.2 2.6 8.3 0.0 6.1 6 0 0 6 6 6 3 FG-GAP repeat TcdB_toxin_midN PF12256.8 EPE25275.1 - 0.00019 20.9 4.6 7.6 5.9 0.1 5.0 2 2 3 5 5 5 2 Insecticide toxin TcdB middle/N-terminal region PliI PF16743.5 EPE25275.1 - 0.0083 15.9 3.3 16 5.3 0.1 4.8 4 1 0 5 5 5 1 Periplasmic lysozyme inhibitor of I-type lysozyme Itfg2 PF15907.5 EPE25275.1 - 0.14 11.1 0.5 15 4.5 0.0 3.5 2 2 2 4 4 4 0 Integrin-alpha FG-GAP repeat-containing protein 2 DUF2666 PF10869.8 EPE25276.1 - 0.0034 17.6 2.6 0.03 14.5 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2666) MRI PF15325.6 EPE25276.1 - 1.2 10.3 11.1 20 6.3 1.7 2.5 1 1 1 2 2 2 0 Modulator of retrovirus infection DUF2052 PF09747.9 EPE25276.1 - 9.6 6.3 9.0 12 5.9 9.0 1.3 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) F-box-like PF12937.7 EPE25279.1 - 0.00072 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE25279.1 - 0.0031 17.3 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EPE25279.1 - 0.03 14.2 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 F-box Zn_clus PF00172.18 EPE25280.1 - 0.027 14.6 14.6 0.051 13.7 14.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPE25281.1 - 5.2e-42 144.0 50.9 1.4e-41 142.6 48.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE25281.1 - 1.5e-12 46.7 26.1 4.8e-12 45.1 26.1 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mannosyl_trans3 PF11051.8 EPE25282.1 - 0.025 14.0 0.1 0.036 13.4 0.1 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Zn_clus PF00172.18 EPE25284.1 - 8.8e-09 35.3 12.8 1.8e-08 34.4 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3348 PF11828.8 EPE25284.1 - 0.13 12.0 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) FAD_binding_3 PF01494.19 EPE25285.1 - 2.8e-19 69.6 0.1 8.6e-18 64.7 0.1 2.6 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EPE25285.1 - 0.00057 19.0 0.0 0.0041 16.2 0.1 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 EPE25285.1 - 0.0025 17.1 0.0 0.0045 16.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE25285.1 - 0.0042 17.3 0.0 0.0089 16.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EPE25285.1 - 0.026 13.8 0.0 0.072 12.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE25285.1 - 0.14 12.7 0.0 0.81 10.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sulf_transp PF04143.14 EPE25286.1 - 9.7e-29 100.9 26.9 9.7e-29 100.9 26.9 2.0 1 1 1 2 2 2 1 Sulphur transport DUF3446 PF11928.8 EPE25287.1 - 0.02 15.2 11.5 0.02 15.2 11.5 6.5 3 2 1 5 5 5 0 Early growth response N-terminal domain DUF3433 PF11915.8 EPE25287.1 - 0.19 12.2 2.9 1.4 9.5 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3433) LAMTOR PF15454.6 EPE25288.1 - 5.1e-14 52.6 0.0 8.2e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator F-box PF00646.33 EPE25290.1 - 1.5e-07 31.1 0.1 2.2e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPE25290.1 - 1.8e-06 27.7 0.8 2.8e-06 27.1 0.8 1.3 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EPE25290.1 - 0.0047 16.8 0.1 0.0071 16.2 0.1 1.2 1 0 0 1 1 1 1 F-box PRANC PF09372.10 EPE25290.1 - 0.17 12.2 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 PRANC domain KCH PF16944.5 EPE25291.1 - 8.3e-99 330.4 3.6 9.9e-99 330.2 3.6 1.1 1 0 0 1 1 1 1 Fungal potassium channel HET PF06985.11 EPE25292.1 - 3.6e-12 46.9 4.5 7e-10 39.4 0.5 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PS-DH PF14765.6 EPE25293.1 - 3.1e-64 217.1 1.0 4.8e-64 216.4 1.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EPE25293.1 - 4e-61 206.1 0.0 1.9e-60 203.9 0.0 2.2 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.26 EPE25293.1 - 6.3e-61 206.1 0.0 1.8e-60 204.6 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EPE25293.1 - 1e-56 192.8 0.0 1.7e-56 192.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE25293.1 - 7.5e-37 125.9 0.0 2.4e-36 124.3 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EPE25293.1 - 1.8e-25 89.6 0.0 4.3e-25 88.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EPE25293.1 - 6.2e-17 62.2 0.0 1.8e-16 60.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EPE25293.1 - 1e-12 48.1 0.0 6.4e-12 45.6 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE25293.1 - 1.8e-12 48.5 0.0 2.3e-11 44.9 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EPE25293.1 - 6.4e-11 42.8 0.0 2.4e-10 41.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE25293.1 - 1.9e-10 41.3 0.0 1.3e-09 38.5 0.0 2.6 3 0 0 3 3 1 1 Methyltransferase domain adh_short PF00106.25 EPE25293.1 - 4.1e-10 39.5 0.0 2.4e-07 30.4 0.0 2.8 2 0 0 2 2 2 2 short chain dehydrogenase Methyltransf_23 PF13489.6 EPE25293.1 - 1.1e-09 38.3 0.0 3e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE25293.1 - 1.3e-08 34.8 0.0 2.7e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 EPE25293.1 - 7.8e-08 32.2 0.5 5.2e-07 29.5 0.6 2.4 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EPE25293.1 - 1.4e-06 28.6 0.1 3.8e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 EPE25293.1 - 0.0023 17.7 0.5 0.016 15.0 0.5 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ubie_methyltran PF01209.18 EPE25293.1 - 0.0065 15.8 0.0 0.11 11.8 0.0 2.7 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.15 EPE25293.1 - 0.018 14.2 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NodS PF05401.11 EPE25293.1 - 0.04 13.5 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 EPE25293.1 - 0.13 11.6 0.0 3.7 6.8 0.0 2.6 2 0 0 2 2 2 0 O-methyltransferase domain 2OG-FeII_Oxy PF03171.20 EPE25294.1 - 7.9e-10 39.1 0.0 1.5e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EPE25294.1 - 0.031 15.0 0.0 0.06 14.1 0.0 1.5 1 1 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Myb_DNA-bind_6 PF13921.6 EPE25295.1 - 1.7e-28 98.6 3.2 5.4e-14 52.2 0.4 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EPE25295.1 - 9.5e-26 89.7 15.3 5.9e-11 42.4 0.6 3.5 4 0 0 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.8 EPE25295.1 - 0.00023 21.2 2.0 0.13 12.4 0.6 2.8 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 EPE25295.1 - 0.0094 15.8 0.0 3.5 7.6 0.0 2.5 1 1 1 2 2 2 2 Myb DNA-binding like Mad3_BUB1_I_2 PF17014.5 EPE25295.1 - 0.043 13.9 0.4 0.44 10.7 0.1 2.1 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein SANT_DAMP1_like PF16282.5 EPE25295.1 - 0.062 13.5 1.0 0.93 9.7 0.1 2.5 1 1 2 3 3 3 0 SANT/Myb-like domain of DAMP1 NDUFA12 PF05071.16 EPE25295.1 - 0.088 13.7 0.2 0.088 13.7 0.2 2.1 2 0 0 2 2 2 0 NADH ubiquinone oxidoreductase subunit NDUFA12 p450 PF00067.22 EPE25296.1 - 2.8e-59 201.1 0.0 3.7e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EPE25297.1 - 6.4e-23 81.2 1.0 2.1e-22 79.5 1.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE25297.1 - 1.3e-12 47.8 0.1 3e-12 46.6 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE25297.1 - 3.5e-06 27.1 0.2 5.6e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 KR domain FAD_binding_4 PF01565.23 EPE25298.1 - 3.1e-21 75.6 2.0 4.8e-21 74.9 2.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE25298.1 - 5.3e-08 32.8 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Dabb PF07876.12 EPE25299.1 - 2.1e-07 31.5 0.2 2.7e-05 24.7 0.1 1.9 1 1 1 2 2 2 2 Stress responsive A/B Barrel Domain NAD_binding_10 PF13460.6 EPE25300.1 - 5.2e-09 36.2 0.0 6.9e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EPE25300.1 - 0.002 17.3 0.0 0.43 9.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Semialdhyde_dh PF01118.24 EPE25300.1 - 0.0024 18.3 0.0 0.0067 16.9 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EPE25300.1 - 0.0036 17.6 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EPE25300.1 - 0.0057 15.8 0.0 0.034 13.3 0.0 2.1 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 EPE25300.1 - 0.0057 16.8 0.1 0.012 15.7 0.1 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.17 EPE25300.1 - 0.0059 15.7 0.1 0.016 14.3 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.21 EPE25300.1 - 0.12 11.8 0.0 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 EPE25301.1 - 1.7e-39 135.7 53.4 2.3e-39 135.4 50.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 EPE25302.1 - 6.3e-52 176.8 0.0 1e-51 176.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3500 PF12006.8 EPE25303.1 - 3.7e-94 315.5 0.0 4.4e-94 315.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) FAA_hydrolase PF01557.18 EPE25304.1 - 2.7e-56 190.7 0.0 3.5e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Polysacc_deac_1 PF01522.21 EPE25305.1 - 4.8e-12 45.9 0.0 7.9e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase HSP70 PF00012.20 EPE25306.1 - 1.9e-260 865.2 14.7 2.2e-260 865.0 14.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EPE25306.1 - 6.2e-19 68.0 2.2 1.4e-17 63.5 0.7 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EPE25306.1 - 0.00016 22.0 4.4 0.73 10.3 0.2 3.6 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 EPE25306.1 - 0.01 15.1 0.9 0.21 10.8 0.1 2.7 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase HET PF06985.11 EPE25307.1 - 2.2e-07 31.3 0.0 3.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EST1_DNA_bind PF10373.9 EPE25308.1 - 3.9e-13 49.5 0.2 9.5e-13 48.3 0.0 1.8 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain Tcp11 PF05794.13 EPE25308.1 - 1.3e-10 41.0 0.0 2.1e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 T-complex protein 11 ALMS_motif PF15309.6 EPE25308.1 - 0.08 13.4 0.3 0.21 12.1 0.3 1.6 1 0 0 1 1 1 0 ALMS motif Ehbp PF10622.9 EPE25308.1 - 0.14 12.2 0.0 31 4.7 0.0 2.7 3 0 0 3 3 3 0 Energy-converting hydrogenase B subunit P (EhbP) Tetraspanin PF00335.20 EPE25309.1 - 0.013 15.3 2.0 0.85 9.3 0.4 2.1 2 0 0 2 2 2 0 Tetraspanin family CorA PF01544.18 EPE25310.1 - 1.5e-07 31.1 13.4 3.9e-07 29.7 13.4 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF21 PF01595.20 EPE25311.1 - 9.5e-30 103.6 0.0 1.6e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EPE25311.1 - 1.9e-07 31.4 0.6 0.039 14.4 0.2 2.9 3 0 0 3 3 3 2 CBS domain Ribosomal_L4 PF00573.22 EPE25311.1 - 6.3 6.4 7.8 0.14 11.8 0.8 1.8 2 0 0 2 2 2 0 Ribosomal protein L4/L1 family CorA PF01544.18 EPE25312.1 - 3.9e-08 33.0 0.0 7.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein p450 PF00067.22 EPE25313.1 - 1.6e-26 93.1 0.0 8.7e-26 90.7 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 zf-met PF12874.7 EPE25314.1 - 0.0023 18.3 0.4 0.0038 17.6 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EPE25314.1 - 0.01 16.1 0.3 0.019 15.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EPE25314.1 - 0.018 15.3 0.2 0.018 15.3 0.2 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 EPE25314.1 - 0.061 13.8 0.1 0.061 13.8 0.1 2.1 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D V_ATPase_I PF01496.19 EPE25314.1 - 0.91 7.4 5.7 1.5 6.7 5.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SPOC PF07744.13 EPE25315.1 - 8.5e-27 93.9 0.0 1.5e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 EPE25315.1 - 4.5e-17 62.5 0.5 1.3e-16 61.1 0.5 1.8 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 EPE25315.1 - 2e-06 27.6 7.7 4.5e-06 26.4 7.7 1.6 1 0 0 1 1 1 1 PHD-finger DUF501 PF04417.12 EPE25316.1 - 0.036 13.9 2.9 0.06 13.1 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF501) TFIIA PF03153.13 EPE25316.1 - 0.06 13.3 9.2 0.099 12.6 9.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RapA_C PF12137.8 EPE25316.1 - 0.44 9.5 7.1 0.6 9.1 7.1 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal MFS_1 PF07690.16 EPE25317.1 - 4.1e-24 85.2 52.8 4.2e-23 81.8 42.5 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EPE25317.1 - 2.7e-05 22.8 22.0 0.00026 19.6 22.0 2.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EPE25319.1 - 1.3e-33 116.4 23.1 1.3e-33 116.4 23.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EPE25320.1 - 5e-54 183.8 0.0 6.8e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 EPE25321.1 - 1.1e-56 192.5 53.4 1.5e-56 192.1 53.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE25321.1 - 1.2e-19 70.2 42.7 1.7e-19 69.8 42.7 1.0 1 0 0 1 1 1 1 Amino acid permease Mersacidin PF16934.5 EPE25322.1 - 7.3 6.4 7.3 42 4.0 3.6 2.3 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) MFS_1 PF07690.16 EPE25325.1 - 1.2e-30 106.6 29.2 1.2e-30 106.6 29.2 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EPE25325.1 - 0.011 14.0 0.4 0.04 12.2 0.1 1.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Zip PF02535.22 EPE25327.1 - 2.1e-53 181.7 2.9 5.3e-53 180.4 2.9 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Cation_efflux PF01545.21 EPE25328.1 - 2.7e-25 89.3 15.0 3.4e-25 89.0 15.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EPE25328.1 - 5.4e-06 26.4 1.2 1.4e-05 25.2 0.9 1.9 1 1 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF3169 PF11368.8 EPE25328.1 - 0.57 9.6 6.7 0.064 12.8 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3169) TMEM154 PF15102.6 EPE25329.1 - 0.025 14.5 0.7 0.057 13.3 0.7 1.6 1 0 0 1 1 1 0 TMEM154 protein family Podoplanin PF05808.11 EPE25329.1 - 0.16 12.0 5.2 0.049 13.7 1.7 1.9 2 0 0 2 2 2 0 Podoplanin Shisa PF13908.6 EPE25329.1 - 0.35 11.1 4.3 0.25 11.5 1.5 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator ADH_zinc_N PF00107.26 EPE25330.1 - 5.8e-20 71.6 0.3 9.1e-20 71.0 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE25330.1 - 4.9e-14 53.5 0.1 1.4e-13 52.0 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE25330.1 - 0.00025 20.9 0.0 0.00054 19.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EPE25330.1 - 0.025 13.9 0.8 0.025 13.9 0.8 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Med7 PF05983.11 EPE25331.1 - 1.7e-65 220.7 0.2 1.9e-65 220.5 0.2 1.0 1 0 0 1 1 1 1 MED7 protein PAP2 PF01569.21 EPE25332.1 - 5.7e-27 94.1 1.5 1.1e-26 93.2 1.2 1.7 2 0 0 2 2 2 1 PAP2 superfamily RseC_MucC PF04246.12 EPE25332.1 - 0.034 14.1 1.4 0.16 11.9 0.1 2.4 3 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC YhhN PF07947.14 EPE25332.1 - 0.083 12.5 1.7 0.33 10.5 0.2 2.2 2 0 0 2 2 2 0 YhhN family PAP2_3 PF14378.6 EPE25332.1 - 0.12 12.0 5.0 1.2 8.8 5.0 2.3 1 1 0 1 1 1 0 PAP2 superfamily DUF5510 PF17629.2 EPE25332.1 - 0.85 9.6 0.0 0.85 9.6 0.0 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5510) DUF5595 PF18077.1 EPE25333.1 - 0.026 14.6 1.6 1.3 9.2 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) FlaC_arch PF05377.11 EPE25333.1 - 1.7 9.1 4.5 3.1 8.3 1.5 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Calmodulin_bind PF07887.11 EPE25334.1 - 0.035 13.4 0.2 0.055 12.8 0.2 1.2 1 0 0 1 1 1 0 Calmodulin binding protein-like Proteasome PF00227.26 EPE25335.1 - 4.7e-61 205.6 0.2 5.7e-61 205.3 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EPE25335.1 - 1.5e-13 50.1 0.2 8.9e-13 47.7 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 EPE25335.1 - 0.014 15.5 0.4 0.036 14.2 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 EPE25335.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit WW PF00397.26 EPE25336.1 - 2.5e-09 37.1 3.3 2.5e-09 37.1 3.3 2.6 2 0 0 2 2 2 1 WW domain FF PF01846.19 EPE25336.1 - 7.4e-07 29.3 0.2 7.4e-07 29.3 0.2 4.0 5 0 0 5 5 5 1 FF domain VGLL4 PF15245.6 EPE25336.1 - 2.3 8.2 4.8 0.3 11.1 0.3 1.7 2 0 0 2 2 2 0 Transcription cofactor vestigial-like protein 4 Tyrosinase PF00264.20 EPE25338.1 - 2.4e-47 162.1 0.6 3.5e-47 161.6 0.6 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EPE25338.1 - 9.7e-26 90.8 0.0 1.6e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain RNA_pol_Rpb2_6 PF00562.28 EPE25339.1 - 3.2e-112 375.4 0.2 4.3e-112 375.0 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EPE25339.1 - 5.1e-34 117.6 0.0 7.7e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EPE25339.1 - 7.3e-29 99.8 0.0 2e-28 98.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EPE25339.1 - 7.1e-26 91.0 0.0 1.2e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EPE25339.1 - 3.6e-23 81.3 0.0 7e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 EPE25339.1 - 5.8e-14 52.3 0.0 3.5e-13 49.8 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 DZR PF12773.7 EPE25339.1 - 0.35 10.9 0.9 0.75 9.9 0.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon Arf PF00025.21 EPE25340.1 - 6.5e-44 149.5 0.0 7.5e-44 149.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EPE25340.1 - 1.1e-18 67.3 0.0 1.3e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE25340.1 - 2e-15 57.1 0.0 3e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EPE25340.1 - 5.6e-07 29.2 0.0 6.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EPE25340.1 - 7.6e-06 25.4 0.0 9.4e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EPE25340.1 - 7.8e-06 25.9 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EPE25340.1 - 7.5e-05 22.0 0.2 0.00054 19.2 0.0 2.4 1 1 1 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 EPE25340.1 - 0.028 14.0 0.3 0.095 12.2 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 EPE25340.1 - 0.085 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 EPE25340.1 - 0.091 12.8 0.0 0.56 10.2 0.1 1.9 1 1 1 2 2 2 0 Dynamin family RCR PF12273.8 EPE25341.1 - 1.8e-24 86.7 8.8 2.8e-24 86.1 8.8 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 EPE25341.1 - 0.0022 17.7 1.6 0.0029 17.3 1.6 1.2 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF3382 PF11862.8 EPE25341.1 - 0.0052 17.0 0.0 0.0073 16.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3382) LysE PF01810.18 EPE25341.1 - 0.011 15.2 0.1 0.015 14.8 0.1 1.1 1 0 0 1 1 1 0 LysE type translocator TMEM132D_C PF15706.5 EPE25341.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Corona_S2 PF01601.16 EPE25342.1 - 2.8 6.3 18.2 3.8 5.9 18.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Pil1 PF13805.6 EPE25343.1 - 1.3e-108 362.5 8.9 1.7e-108 362.2 8.9 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Mur_ligase_C PF02875.21 EPE25343.1 - 0.073 13.3 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain APG6_N PF17675.1 EPE25343.1 - 0.13 12.8 9.1 1.9 9.0 4.9 2.9 3 0 0 3 3 3 0 Apg6 coiled-coil region BAR_3 PF16746.5 EPE25343.1 - 0.14 11.9 5.6 0.14 11.8 3.3 1.9 2 0 0 2 2 2 0 BAR domain of APPL family GFO_IDH_MocA PF01408.22 EPE25344.1 - 1.8e-13 51.3 0.0 2.8e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ank_2 PF12796.7 EPE25345.1 - 6.1e-13 49.2 0.0 3.6e-07 30.7 0.0 4.0 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE25345.1 - 3.8e-11 43.3 0.0 0.0027 18.3 0.0 4.3 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE25345.1 - 1.6e-10 40.3 0.0 0.23 12.1 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EPE25345.1 - 1.5e-07 31.5 0.0 0.15 12.5 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EPE25345.1 - 8.8e-07 29.1 0.0 0.83 10.2 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat ADH_N PF08240.12 EPE25345.1 - 5.6e-06 26.2 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fungal_lectin_2 PF18647.1 EPE25348.1 - 2.3e-16 60.1 0.0 6.2e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Alpha-galactosyl-binding fungal lectin Peptidase_S8 PF00082.22 EPE25348.1 - 3.2e-07 29.9 0.0 5.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Pkinase PF00069.25 EPE25349.1 - 7.3e-43 146.8 0.0 1.2e-42 146.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE25349.1 - 1.3e-22 80.3 0.0 2.2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EPE25349.1 - 1.5e-08 34.9 0.4 4.3e-08 33.4 0.4 1.8 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EPE25349.1 - 0.00043 19.7 0.0 0.0018 17.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EPE25349.1 - 0.0047 15.8 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EPE25349.1 - 0.0049 16.3 0.0 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 EPE25349.1 - 0.0055 17.0 0.1 0.023 15.0 0.0 2.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain YrbL-PhoP_reg PF10707.9 EPE25349.1 - 0.021 14.3 0.1 0.15 11.5 0.1 2.1 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 EPE25349.1 - 0.088 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase NusG_add PF18298.1 EPE25349.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 NusG additional domain SHE3 PF17078.5 EPE25349.1 - 0.44 10.2 1.7 0.38 10.4 0.2 1.6 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Usg PF06233.12 EPE25350.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Usg-like family NPV_P10 PF05531.12 EPE25351.1 - 0.053 14.0 0.0 8.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HBM PF16591.5 EPE25351.1 - 0.07 12.6 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Helical bimodular sensor domain NepR PF18557.1 EPE25351.1 - 1.8 8.3 5.8 37 4.1 0.1 3.7 4 0 0 4 4 4 0 Anti-sigma factor NepR Phyto_Pns9_10 PF05878.11 EPE25352.1 - 0.038 13.1 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Acetyltransf_3 PF13302.7 EPE25353.1 - 2e-17 64.2 0.0 2.9e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE25353.1 - 6.1e-05 23.2 0.0 7.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EPE25353.1 - 0.023 14.8 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IlvC PF01450.19 EPE25353.1 - 0.044 14.1 0.0 0.071 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF2527 PF10736.9 EPE25353.1 - 0.18 11.6 0.1 0.33 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) E1-E2_ATPase PF00122.20 EPE25354.1 - 3.4e-48 163.6 0.4 3.8e-47 160.2 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EPE25354.1 - 7.2e-39 134.3 0.1 1.4e-38 133.3 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EPE25354.1 - 4.7e-37 126.2 3.0 6.4e-11 42.5 0.4 4.9 4 1 0 4 4 4 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EPE25354.1 - 9.5e-05 22.3 0.2 0.0026 17.6 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EPE25354.1 - 0.0028 18.1 0.0 0.0065 16.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UPF0180 PF03698.13 EPE25354.1 - 0.13 12.4 0.0 0.92 9.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) Sigma_reg_N PF13800.6 EPE25354.1 - 0.14 12.5 0.4 0.39 11.1 0.4 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Caveolin PF01146.17 EPE25354.1 - 8.9 6.3 6.8 13 5.8 2.6 2.4 2 0 0 2 2 2 0 Caveolin ShlB PF03865.13 EPE25356.1 - 0.032 13.7 2.0 3.4 7.0 0.1 2.2 2 0 0 2 2 2 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Fil_haemagg_2 PF13332.6 EPE25356.1 - 0.14 12.3 3.0 1.2 9.3 0.1 2.5 2 0 0 2 2 2 0 Hemagglutinin repeat DUF1996 PF09362.10 EPE25357.1 - 2.2e-46 158.7 0.0 2.8e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Methyltransf_25 PF13649.6 EPE25358.1 - 2e-10 41.2 0.0 4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE25358.1 - 4.6e-09 36.3 0.0 1e-08 35.2 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE25358.1 - 1.9e-08 34.9 0.0 3.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE25358.1 - 4.6e-07 30.4 0.0 7.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE25358.1 - 5e-06 26.4 0.0 6.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EPE25358.1 - 0.0026 17.1 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain DREV PF05219.12 EPE25358.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 EPE25358.1 - 0.014 15.0 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF938 PF06080.12 EPE25358.1 - 0.025 14.3 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.19 EPE25358.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EPE25358.1 - 0.18 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 EPE25358.1 - 0.18 11.8 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 EPE25358.1 - 0.18 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_4 PF02390.17 EPE25358.1 - 0.19 11.2 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF2569 PF10754.9 EPE25359.1 - 0.004 17.6 2.0 0.004 17.6 2.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2569) DUF2214 PF09980.9 EPE25359.1 - 1.3 8.8 7.5 0.13 12.1 1.0 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2214) DUF3328 PF11807.8 EPE25360.1 - 1.9e-32 112.8 0.7 2.4e-32 112.5 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.16 EPE25361.1 - 2.4e-47 161.6 30.0 2.4e-47 161.6 30.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE25361.1 - 8.9e-12 44.6 10.3 8.9e-12 44.6 10.3 3.2 1 1 2 3 3 3 1 Sugar (and other) transporter Porin_7 PF16956.5 EPE25361.1 - 0.17 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative general bacterial porin Amidohydro_1 PF01979.20 EPE25362.1 - 6.3e-40 137.5 0.1 7.9e-40 137.2 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPE25362.1 - 4.4e-18 66.0 1.8 2.3e-10 40.6 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family STI1 PF17830.1 EPE25362.1 - 0.0049 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 STI1 domain Fungal_trans_2 PF11951.8 EPE25363.1 - 1.8e-41 142.2 0.1 2.3e-41 141.9 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE25363.1 - 2.8e-09 36.9 6.0 2.8e-09 36.9 6.0 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UME PF08064.13 EPE25363.1 - 0.071 13.0 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 UME (NUC010) domain Aminotran_3 PF00202.21 EPE25364.1 - 2e-55 188.1 0.0 3.9e-55 187.2 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class-III DUF1682 PF07946.14 EPE25365.1 - 2.5 7.2 6.6 1.7 7.7 4.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Peptidase_S8 PF00082.22 EPE25367.1 - 6.8e-14 51.8 0.1 9.6e-14 51.3 0.1 1.3 1 0 0 1 1 1 1 Subtilase family Fungal_lectin_2 PF18647.1 EPE25367.1 - 2.6e-13 50.3 0.0 5.4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Alpha-galactosyl-binding fungal lectin CAP_N PF01213.19 EPE25367.1 - 0.11 11.9 5.2 0.25 10.8 5.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 EPE25367.1 - 0.35 10.9 4.3 0.85 9.7 4.3 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Amidase PF01425.21 EPE25370.1 - 5e-102 342.2 0.0 6.2e-102 341.9 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF807 PF05660.11 EPE25370.1 - 0.0064 16.5 0.4 0.066 13.2 0.0 2.2 2 0 0 2 2 2 1 Coxiella burnetii protein of unknown function (DUF807) 2OG-FeII_Oxy_2 PF13532.6 EPE25371.1 - 7e-33 114.5 0.0 3.2e-32 112.3 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily S100PBPR PF15427.6 EPE25371.1 - 0.21 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 S100P-binding protein Pkinase PF00069.25 EPE25372.1 - 3.5e-71 239.6 0.0 4.8e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE25372.1 - 1.7e-31 109.5 0.0 2.1e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE25372.1 - 0.0009 18.6 0.0 0.0018 17.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EPE25372.1 - 0.0014 17.7 0.1 0.014 14.4 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EPE25372.1 - 0.0066 16.4 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EPE25372.1 - 0.019 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EPE25372.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HET PF06985.11 EPE25374.1 - 4.8e-28 98.3 0.4 1.4e-26 93.6 0.4 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyoxalase PF00903.25 EPE25375.1 - 5.4e-05 23.4 0.0 9.1e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2400 PF09674.10 EPE25375.1 - 0.16 11.9 0.0 0.2 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) HET PF06985.11 EPE25376.1 - 4.3e-25 88.8 0.0 7.2e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3433 PF11915.8 EPE25377.1 - 0.092 13.2 2.5 0.16 12.4 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3433) HET PF06985.11 EPE25378.1 - 1.9e-23 83.4 3.7 3.1e-23 82.8 3.7 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.24 EPE25379.1 - 5.1e-80 269.5 24.1 5.9e-80 269.3 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE25379.1 - 1.7e-29 102.8 34.6 2.6e-21 75.9 15.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ketoacyl-synt PF00109.26 EPE25381.1 - 7.2e-68 228.9 0.1 1.8e-67 227.6 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EPE25381.1 - 3.4e-54 184.1 0.1 7.1e-54 183.1 0.1 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EPE25381.1 - 2.7e-52 178.3 0.0 4.7e-52 177.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EPE25381.1 - 2.7e-48 164.2 0.1 8.6e-48 162.6 0.1 2.0 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 EPE25381.1 - 7.3e-36 122.8 0.1 2.7e-35 120.9 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EPE25381.1 - 2.9e-19 69.7 0.0 1.3e-18 67.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EPE25381.1 - 9.4e-18 64.7 0.0 3.9e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EPE25381.1 - 1.7e-15 57.0 0.1 2.3e-13 50.0 0.0 2.9 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 EPE25381.1 - 1.2e-13 52.3 0.0 2.8e-12 47.8 0.0 3.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPE25381.1 - 2.3e-12 47.0 2.2 3.7e-11 43.1 0.0 3.7 4 0 0 4 4 4 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EPE25381.1 - 3.3e-12 46.6 0.0 9.2e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE25381.1 - 2.5e-11 44.2 0.0 9.2e-11 42.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE25381.1 - 2.5e-09 37.6 0.0 1.2e-08 35.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EPE25381.1 - 1.2e-07 31.5 0.5 4.2e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 EPE25381.1 - 6.7e-07 29.2 0.0 1.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EPE25381.1 - 4.1e-06 27.1 0.5 1.3e-05 25.5 0.5 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 EPE25381.1 - 1.3e-05 24.6 0.0 4.3e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EPE25381.1 - 0.0026 17.5 0.1 0.2 11.4 0.0 2.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ADH_N PF08240.12 EPE25381.1 - 0.0032 17.3 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain LEM PF03020.15 EPE25381.1 - 0.022 14.3 0.0 0.069 12.7 0.0 1.9 1 0 0 1 1 1 0 LEM domain GDP_Man_Dehyd PF16363.5 EPE25381.1 - 0.034 13.5 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EPE25381.1 - 0.042 13.3 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 EPE25381.1 - 0.046 13.1 0.1 0.13 11.6 0.1 1.7 1 0 0 1 1 1 0 Thiolase, N-terminal domain NUT PF12881.7 EPE25381.1 - 0.052 12.0 0.0 0.08 11.4 0.0 1.1 1 0 0 1 1 1 0 NUT protein Zn_clus PF00172.18 EPE25382.1 - 4e-06 26.8 9.2 4e-06 26.8 9.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transferase PF02458.15 EPE25383.1 - 2.8e-09 36.1 0.0 1e-05 24.4 0.0 2.9 2 1 0 2 2 2 2 Transferase family p450 PF00067.22 EPE25384.1 - 3.7e-65 220.5 0.0 4.8e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Arc_C PF18162.1 EPE25384.1 - 0.081 12.8 0.1 0.82 9.6 0.0 2.4 2 0 0 2 2 2 0 Arc C-lobe UDPGT PF00201.18 EPE25385.1 - 7.1e-05 21.8 0.0 9e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Mito_fiss_Elm1 PF06258.11 EPE25385.1 - 0.16 11.0 0.1 0.58 9.2 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial fission ELM1 Rap1_C PF11626.8 EPE25386.1 - 3.7e-21 75.0 0.1 3.7e-21 75.0 0.1 2.9 4 0 0 4 4 4 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EPE25386.1 - 4.5e-21 74.8 3.6 2.1e-16 59.9 0.3 2.9 2 1 0 2 2 2 2 Rap1 Myb domain ARID PF01388.21 EPE25386.1 - 9.9e-15 55.0 0.0 2.1e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BRCT_2 PF16589.5 EPE25386.1 - 4.4e-13 49.5 0.0 9.7e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 EPE25386.1 - 5.5e-07 30.2 6.8 0.00022 21.8 0.0 3.8 2 1 1 3 3 3 2 Rap1, DNA-binding Myb_DNA-binding PF00249.31 EPE25386.1 - 0.5 10.6 5.5 8.6 6.7 0.3 4.2 5 0 0 5 5 5 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPE25386.1 - 5 7.5 10.8 9.8 6.5 2.6 4.0 4 0 0 4 4 4 0 Myb-like DNA-binding domain DHHC PF01529.20 EPE25387.1 - 1.2e-31 109.5 7.8 1.2e-31 109.5 7.8 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Fungal_trans_2 PF11951.8 EPE25388.1 - 2.1e-12 46.6 3.5 4e-12 45.7 3.5 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE25388.1 - 0.0055 16.8 7.2 0.0088 16.1 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ytp1 PF10355.9 EPE25389.1 - 9.2e-96 320.3 22.1 3.9e-91 305.1 6.7 2.7 2 1 1 3 3 3 2 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EPE25389.1 - 6.5e-23 80.5 2.4 6.5e-23 80.5 2.4 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) DUF1129 PF06570.11 EPE25389.1 - 0.33 10.4 5.6 0.23 10.9 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) TadE PF07811.12 EPE25389.1 - 0.79 10.0 5.7 10 6.5 0.1 3.8 3 0 0 3 3 3 0 TadE-like protein zf-Di19 PF05605.12 EPE25390.1 - 0.037 14.3 0.2 0.11 12.8 0.2 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Kre28 PF17097.5 EPE25390.1 - 0.048 12.6 0.8 0.085 11.8 0.8 1.5 1 0 0 1 1 1 0 Spindle pole body component zf-C2H2_4 PF13894.6 EPE25390.1 - 0.09 13.7 0.6 0.29 12.1 0.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger NAM-associated PF14303.6 EPE25390.1 - 9.1 7.0 9.0 0.85 10.3 3.5 2.1 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain zf-C2H2_2 PF12756.7 EPE25391.1 - 6.6e-32 109.9 22.0 8.1e-30 103.2 0.8 3.9 4 0 0 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EPE25391.1 - 7.6e-08 32.5 2.2 2.2e-05 24.6 0.9 4.7 5 1 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPE25391.1 - 0.00019 21.7 7.9 0.00057 20.2 0.9 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EPE25391.1 - 0.0029 18.3 24.1 0.94 10.5 0.1 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger AKAP95 PF04988.12 EPE25391.1 - 0.0094 16.2 1.2 1.3 9.3 0.0 3.1 2 1 1 3 3 3 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.26 EPE25391.1 - 0.083 13.4 0.4 0.083 13.4 0.4 5.1 5 0 0 5 5 5 0 Zinc finger, C2H2 type HECT PF00632.25 EPE25392.1 - 7.1e-70 235.9 0.0 9.8e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 EPE25392.1 - 7.2e-20 71.0 1.5 1.4e-19 70.0 1.5 1.5 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A PAC4 PF16093.5 EPE25392.1 - 0.32 11.2 2.5 0.35 11.1 0.1 2.2 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 Zn_clus PF00172.18 EPE25395.1 - 7.4 6.8 8.4 31 4.8 3.0 3.0 1 1 2 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EPE25396.1 - 0.0036 17.4 8.8 0.0065 16.6 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EPE25396.1 - 0.17 11.9 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 PAS fold MFS_1 PF07690.16 EPE25398.1 - 1.9e-44 152.1 26.7 1.9e-44 152.1 26.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE25398.1 - 2e-09 36.4 2.0 2e-09 36.4 2.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPE25398.1 - 2.3e-09 36.7 4.0 2.3e-09 36.7 4.0 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Flavokinase PF01687.17 EPE25399.1 - 8.9e-30 103.3 0.0 1.5e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase Apolipoprotein PF01442.18 EPE25400.1 - 0.0015 18.4 0.5 0.0039 17.1 0.5 1.6 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain CLZ PF16526.5 EPE25400.1 - 0.013 15.8 0.1 0.064 13.6 0.1 2.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Rx_N PF18052.1 EPE25400.1 - 0.094 13.0 0.3 0.22 11.8 0.3 1.6 1 0 0 1 1 1 0 Rx N-terminal domain AA_permease_2 PF13520.6 EPE25401.1 - 3.5e-55 187.6 32.6 6.3e-53 180.1 32.6 2.1 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 EPE25402.1 - 2.6e-30 105.4 27.9 3.1e-30 105.2 27.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TMEM65 PF10507.9 EPE25402.1 - 0.0072 16.3 2.0 2.9 7.9 0.1 2.7 2 1 0 2 2 2 2 Transmembrane protein 65 NACHT PF05729.12 EPE25403.1 - 2.1e-09 37.5 0.0 6.4e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EPE25403.1 - 4.3e-05 23.8 1.3 0.0029 17.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain SesA PF17107.5 EPE25403.1 - 0.00012 22.2 3.1 0.00012 22.2 3.1 2.6 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 EPE25403.1 - 0.0012 19.2 0.0 0.0058 17.0 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EPE25403.1 - 0.0047 17.5 0.4 0.12 12.9 0.0 2.8 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 EPE25403.1 - 0.016 15.8 0.0 0.15 12.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain KI67R PF08065.12 EPE25403.1 - 0.027 15.0 3.5 0.088 13.4 3.5 1.9 1 0 0 1 1 1 0 KI67R (NUC007) repeat AAA_30 PF13604.6 EPE25403.1 - 0.049 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EPE25403.1 - 0.094 12.5 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Jacalin PF01419.17 EPE25404.1 - 0.00023 21.1 0.0 0.00052 20.0 0.1 1.6 1 1 0 1 1 1 1 Jacalin-like lectin domain Mur_ligase_C PF02875.21 EPE25404.1 - 0.063 13.5 0.1 0.23 11.7 0.1 1.9 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain UDPGT PF00201.18 EPE25405.1 - 0.0015 17.5 0.0 0.0062 15.4 0.0 1.8 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase B12-binding PF02310.19 EPE25406.1 - 0.029 14.4 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain VHS PF00790.19 EPE25409.1 - 3.8e-14 52.7 0.1 8.1e-14 51.7 0.0 1.6 2 0 0 2 2 2 1 VHS domain DUF5578 PF17741.1 EPE25409.1 - 0.074 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5578) Lyase_1 PF00206.20 EPE25410.1 - 7.8e-23 81.3 0.0 1.2e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EPE25410.1 - 2.5e-17 63.2 0.0 8.7e-17 61.4 0.0 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF4690 PF15756.5 EPE25411.1 - 0.059 14.0 1.5 0.12 13.0 1.5 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Fasciclin PF02469.22 EPE25412.1 - 3.5e-46 156.6 0.0 1.1e-25 90.2 0.0 2.9 3 0 0 3 3 3 2 Fasciclin domain Pyridoxal_deC PF00282.19 EPE25413.1 - 3.1e-60 203.9 0.0 4.5e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EPE25413.1 - 4.5e-05 22.6 0.0 9.9e-05 21.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Glyoxalase PF00903.25 EPE25415.1 - 8.2e-41 139.2 0.2 7.7e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EPE25415.1 - 2.8e-16 59.7 0.0 5.9e-06 26.5 0.0 3.9 3 1 0 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EPE25415.1 - 9.5e-08 32.8 0.0 0.0035 18.1 0.0 3.0 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EPE25415.1 - 1.6e-06 28.3 0.0 0.073 13.2 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EPE25415.1 - 1.6e-05 24.8 3.6 0.94 9.4 0.1 4.7 4 2 2 6 6 6 1 Glyoxalase-like domain DUF1338 PF07063.13 EPE25415.1 - 0.00077 18.7 0.0 2.9 7.0 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF1338) CppA_N PF14506.6 EPE25415.1 - 0.0052 16.9 0.3 1.8 8.7 0.1 2.3 2 0 0 2 2 2 2 CppA N-terminal Pfk_N PF18468.1 EPE25415.1 - 0.016 15.6 0.4 0.49 10.8 0.0 2.6 2 0 0 2 2 2 0 Phosphofructokinase N-terminal domain yeast MoaF PF10703.9 EPE25415.1 - 0.029 14.3 0.1 1 9.3 0.0 2.4 2 0 0 2 2 2 0 MoaF N-terminal domain EMP70 PF02990.16 EPE25415.1 - 0.061 12.0 0.0 0.084 11.5 0.0 1.2 1 0 0 1 1 1 0 Endomembrane protein 70 Acetyltransf_10 PF13673.7 EPE25415.1 - 0.075 13.0 0.2 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain 2-Hacid_dh_C PF02826.19 EPE25416.1 - 9.3e-53 178.2 0.0 1.7e-52 177.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPE25416.1 - 7.6e-36 122.7 0.6 7.2e-35 119.6 0.1 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 EPE25416.1 - 8.2e-05 22.3 6.4 0.00015 21.5 0.1 3.3 3 1 0 3 3 3 1 ACT domain Asparaginase PF00710.20 EPE25417.1 - 8.3e-50 169.0 2.4 8.3e-50 169.0 2.4 1.6 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EPE25417.1 - 1.6e-19 70.2 0.0 8e-19 67.9 0.0 2.2 3 0 0 3 3 3 1 Glutaminase/Asparaginase C-terminal domain Cas_csx3 PF09620.10 EPE25417.1 - 0.16 11.8 0.1 0.93 9.4 0.1 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_csx3) Abhydrolase_2 PF02230.16 EPE25419.1 - 2.2e-27 96.3 0.0 2.1e-18 66.9 0.1 2.3 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EPE25419.1 - 5.4e-09 35.8 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EPE25419.1 - 0.00052 20.7 0.0 0.49 11.0 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE25419.1 - 0.0011 18.6 0.3 0.075 12.7 0.0 2.4 2 1 1 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE25419.1 - 0.0012 18.2 0.0 0.29 10.4 0.0 2.9 2 1 0 3 3 3 2 Serine aminopeptidase, S33 LIP PF03583.14 EPE25419.1 - 0.0021 17.4 0.0 0.004 16.5 0.0 1.4 2 0 0 2 2 2 1 Secretory lipase Fungal_trans_2 PF11951.8 EPE25420.1 - 0.00033 19.6 0.1 0.00044 19.2 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_3 PF01596.17 EPE25421.1 - 2.7e-44 150.9 0.0 3.4e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EPE25421.1 - 2.3e-14 54.3 0.0 9.4e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EPE25421.1 - 6.2e-09 35.9 0.0 9.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EPE25421.1 - 8.8e-06 25.6 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE25421.1 - 4.3e-05 24.1 0.0 7.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EPE25421.1 - 0.00049 20.1 0.0 0.00083 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EPE25421.1 - 0.002 17.5 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 EPE25421.1 - 0.004 16.9 0.0 0.0049 16.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Cons_hypoth95 PF03602.15 EPE25421.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 EPE25421.1 - 0.04 13.4 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 EPE25421.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase ParD_antitoxin PF03693.14 EPE25421.1 - 0.17 12.4 0.0 0.34 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 4HBT PF03061.22 EPE25422.1 - 1.8e-08 34.6 0.1 3.3e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily FMN_red PF03358.15 EPE25423.1 - 9.7e-24 83.9 0.0 1.3e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase zf-RING_2 PF13639.6 EPE25424.1 - 3.8e-09 36.7 4.4 3.8e-09 36.7 4.4 2.9 3 0 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EPE25424.1 - 2.3e-08 33.9 0.6 2.3e-08 33.9 0.6 2.9 3 0 0 3 3 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EPE25424.1 - 5.5e-05 23.0 5.0 0.00017 21.5 1.6 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EPE25424.1 - 8e-05 22.3 3.7 0.0028 17.4 1.3 2.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EPE25424.1 - 0.00013 21.8 3.3 0.00031 20.5 1.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE25424.1 - 0.00017 21.4 1.4 0.011 15.6 0.2 3.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE25424.1 - 0.00033 20.5 5.7 0.00078 19.3 2.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPE25424.1 - 0.0033 17.5 1.7 0.0033 17.5 1.7 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EPE25424.1 - 0.0073 16.6 7.1 0.028 14.7 4.1 3.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EPE25424.1 - 0.0085 15.9 2.4 0.0085 15.9 2.4 2.4 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EPE25424.1 - 0.021 14.9 4.3 0.033 14.2 0.6 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE PF01363.21 EPE25424.1 - 0.052 13.7 3.0 0.71 10.1 1.7 2.8 2 1 0 2 2 2 0 FYVE zinc finger Pellino PF04710.14 EPE25424.1 - 0.077 11.6 0.1 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 Pellino GIT1_C PF12205.8 EPE25424.1 - 0.2 11.8 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Zn_ribbon_17 PF17120.5 EPE25424.1 - 0.23 11.1 4.1 0.14 11.8 1.0 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EPE25424.1 - 1.3 9.2 7.1 0.5 10.5 2.9 2.5 2 1 0 2 2 2 0 RING-variant domain zf-met PF12874.7 EPE25424.1 - 1.8 9.1 0.0 1.8 9.1 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF1275 PF06912.11 EPE25425.1 - 2.5e-50 171.1 10.0 3e-50 170.8 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) ABC_tran PF00005.27 EPE25426.1 - 1.3e-48 165.0 0.1 1.9e-26 93.2 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EPE25426.1 - 2.7e-13 50.4 7.1 0.0011 18.9 0.0 4.8 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPE25426.1 - 2.7e-10 40.1 4.8 0.0016 17.9 0.0 4.3 3 2 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EPE25426.1 - 3e-09 37.7 2.6 0.00015 22.3 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EPE25426.1 - 2e-07 30.6 1.1 0.0024 17.6 0.3 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Chromo PF00385.24 EPE25426.1 - 2.5e-06 27.3 0.7 6.2e-06 26.0 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MMR_HSR1 PF01926.23 EPE25426.1 - 2.5e-06 27.5 0.0 0.055 13.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPE25426.1 - 4.9e-06 26.6 0.2 0.041 13.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 EPE25426.1 - 0.00022 21.0 0.9 0.13 11.9 0.3 2.8 2 1 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 EPE25426.1 - 0.00079 19.6 2.5 0.43 10.6 0.3 3.4 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_28 PF13521.6 EPE25426.1 - 0.00084 19.6 0.0 0.083 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPE25426.1 - 0.0017 18.7 0.3 1.9 8.8 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EPE25426.1 - 0.0034 17.9 0.2 5.7 7.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_13 PF13166.6 EPE25426.1 - 0.0052 15.5 1.7 0.62 8.6 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EPE25426.1 - 0.0079 16.4 0.0 1.8 8.8 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 EPE25426.1 - 0.012 15.5 0.6 0.92 9.4 0.0 2.6 2 0 0 2 2 2 0 NACHT domain QWRF PF04484.12 EPE25426.1 - 0.012 15.3 5.5 0.032 14.0 0.0 2.3 2 0 0 2 2 2 0 QWRF family RNA_helicase PF00910.22 EPE25426.1 - 0.014 15.8 0.5 2.7 8.4 0.0 2.9 3 0 0 3 3 2 0 RNA helicase Dynamin_N PF00350.23 EPE25426.1 - 0.022 14.8 0.1 0.62 10.1 0.0 2.7 3 0 0 3 3 2 0 Dynamin family AAA_30 PF13604.6 EPE25426.1 - 0.037 13.7 3.4 5.3 6.7 0.3 3.5 5 0 0 5 5 4 0 AAA domain MukB PF04310.12 EPE25426.1 - 0.049 13.4 0.3 8.3 6.1 0.2 2.5 2 0 0 2 2 2 0 MukB N-terminal PduV-EutP PF10662.9 EPE25426.1 - 0.086 12.6 0.1 4.1 7.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_27 PF13514.6 EPE25426.1 - 0.089 12.4 0.9 6.6 6.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 EPE25426.1 - 0.092 13.2 0.1 7.2 7.0 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 EPE25426.1 - 0.093 12.6 0.0 8.5 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MeaB PF03308.16 EPE25426.1 - 0.12 11.3 0.9 7.6 5.4 0.1 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 EPE25426.1 - 0.28 10.9 2.2 6.8 6.4 0.3 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EPE25426.1 - 0.34 10.2 2.9 4.6 6.5 0.1 2.9 3 0 0 3 3 3 0 Zeta toxin SR-25 PF10500.9 EPE25426.1 - 0.89 9.1 11.7 1.1 8.8 10.1 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3584 PF12128.8 EPE25426.1 - 3.6 5.0 10.2 1 6.8 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) DUF4448 PF14610.6 EPE25427.1 - 6.3e-05 22.8 0.1 0.046 13.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4448) TMEM154 PF15102.6 EPE25427.1 - 0.00018 21.5 0.4 0.49 10.3 0.1 2.4 2 0 0 2 2 2 2 TMEM154 protein family Orf78 PF06024.12 EPE25427.1 - 0.00028 21.1 0.0 0.11 12.8 0.0 2.3 2 0 0 2 2 2 1 Orf78 (ac78) TRP PF06011.12 EPE25427.1 - 0.00059 18.7 1.6 0.002 17.0 0.1 2.0 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel EphA2_TM PF14575.6 EPE25427.1 - 0.0015 19.4 0.1 3.6 8.5 0.0 2.4 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.18 EPE25427.1 - 0.0022 18.2 1.5 1.3 9.3 0.2 2.7 2 0 0 2 2 2 2 Glycophorin A Rax2 PF12768.7 EPE25427.1 - 0.0026 17.2 0.7 1.7 8.1 0.2 2.3 2 0 0 2 2 2 2 Cortical protein marker for cell polarity DUF2207 PF09972.9 EPE25427.1 - 0.0055 15.5 0.2 0.68 8.6 0.0 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) DUF1180 PF06679.12 EPE25427.1 - 0.0081 16.6 6.1 0.39 11.1 0.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1180) Gram_pos_anchor PF00746.21 EPE25427.1 - 0.0099 15.8 5.9 0.054 13.4 0.7 3.0 2 0 0 2 2 2 1 LPXTG cell wall anchor motif BatD PF13584.6 EPE25427.1 - 0.015 14.1 0.0 0.8 8.4 0.0 2.1 2 0 0 2 2 2 0 Oxygen tolerance DUF5305 PF17231.2 EPE25427.1 - 0.016 14.6 0.5 0.41 10.0 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DAG1 PF05454.11 EPE25427.1 - 0.018 14.4 0.8 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) RIFIN PF02009.16 EPE25427.1 - 0.021 14.7 0.3 0.46 10.3 0.1 2.1 2 0 0 2 2 2 0 Rifin DUF4381 PF14316.6 EPE25427.1 - 0.033 14.4 0.0 8.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2569 PF10754.9 EPE25427.1 - 0.051 14.0 0.7 2.8 8.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) TMEM132D_C PF15706.5 EPE25427.1 - 0.1 12.4 0.3 2 8.2 0.1 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF202 PF02656.15 EPE25427.1 - 0.58 10.6 3.9 3.8 8.0 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Phage_holin_3_6 PF07332.11 EPE25427.1 - 0.59 10.2 4.7 5.1 7.2 0.2 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Stevor PF17410.2 EPE25427.1 - 2.4 7.7 5.2 3.6 7.1 0.4 2.7 2 1 0 3 3 3 0 Subtelomeric Variable Open Reading frame Insulin_TMD PF17870.1 EPE25427.1 - 3.8 7.7 6.9 5.4 7.2 0.2 2.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment TrbL PF04610.14 EPE25427.1 - 4.8 6.9 10.8 1.1 9.0 3.4 2.3 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein RSN1_TM PF13967.6 EPE25427.1 - 4.8 6.9 5.5 25 4.6 1.3 2.5 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport Rax2 PF12768.7 EPE25428.1 - 0.00032 20.2 0.0 0.00052 19.5 0.0 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TMEM154 PF15102.6 EPE25429.1 - 0.018 14.9 0.6 0.028 14.3 0.6 1.6 1 1 0 1 1 1 0 TMEM154 protein family FAM176 PF14851.6 EPE25429.1 - 0.039 13.6 0.2 0.054 13.2 0.2 1.2 1 0 0 1 1 1 0 FAM176 family Protocadherin PF08374.11 EPE25429.1 - 0.053 13.5 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Protocadherin TMEM51 PF15345.6 EPE25429.1 - 0.092 12.6 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Ly49 PF08391.10 EPE25429.1 - 0.094 13.1 0.1 0.14 12.5 0.1 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF2681 PF10883.8 EPE25429.1 - 0.097 13.1 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) EphA2_TM PF14575.6 EPE25429.1 - 0.14 13.1 0.0 0.21 12.5 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OSTbeta PF15048.6 EPE25429.1 - 0.15 12.2 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein FixS PF03597.15 EPE25429.1 - 3 7.6 4.5 0.72 9.6 1.5 1.5 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Chitin_bind_1 PF00187.19 EPE25430.1 - 1.8e-09 37.9 20.3 6.4e-09 36.1 20.3 2.0 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_61 PF03443.14 EPE25430.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 Abhydrolase_1 PF00561.20 EPE25431.1 - 1.4e-26 93.7 0.0 1.6e-21 77.1 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE25431.1 - 2.7e-10 41.2 0.0 3.9e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE25431.1 - 4.9e-07 29.3 0.0 8.2e-05 22.0 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EPE25431.1 - 0.017 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DASH_Hsk3 PF08227.11 EPE25432.1 - 2.1e-20 72.8 2.7 2.8e-20 72.4 2.7 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like zf-CHY PF05495.12 EPE25433.1 - 9.6e-11 42.0 9.9 9.6e-11 42.0 9.9 3.6 3 1 0 3 3 3 1 CHY zinc finger CAF1A PF12253.8 EPE25433.1 - 0.16 12.1 2.8 0.37 11.0 2.8 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Cytochrome_C7 PF14522.6 EPE25433.1 - 0.8 9.7 18.6 8.7 6.4 9.5 3.6 3 0 0 3 3 3 0 Cytochrome c7 and related cytochrome c DUF3295 PF11702.8 EPE25434.1 - 1.2e-166 556.0 41.9 4.6e-166 554.0 41.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 EPE25434.1 - 1.8e-10 40.4 2.7 1.8e-10 40.4 2.7 1.9 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) HET PF06985.11 EPE25439.1 - 2.3e-26 92.9 0.0 4e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF5311 PF17238.2 EPE25440.1 - 0.076 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5311) Methyltransf_2 PF00891.18 EPE25441.1 - 4e-25 88.4 0.0 6.9e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 EPE25441.1 - 0.0047 16.4 0.0 0.0082 15.6 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain DOT1 PF08123.13 EPE25441.1 - 0.0096 15.5 0.1 0.13 11.8 0.1 2.3 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 EPE25441.1 - 0.033 14.9 0.0 0.098 13.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EPE25441.1 - 0.033 14.9 0.0 0.091 13.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EPE25441.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.22 EPE25442.1 - 7.1e-55 186.6 0.0 9.3e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MukB_hinge PF16330.5 EPE25442.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 MukB hinge domain RTA1 PF04479.13 EPE25444.1 - 7.1e-65 218.5 12.5 1e-64 218.0 12.5 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4736 PF15883.5 EPE25444.1 - 0.0007 19.4 1.3 0.29 10.9 0.0 2.5 2 1 1 3 3 3 2 Domain of unknown function (DUF4736) DUF3007 PF11460.8 EPE25444.1 - 0.079 13.2 3.7 1.9 8.8 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) PAN_4 PF14295.6 EPE25445.1 - 0.065 13.1 0.7 0.13 12.1 0.7 1.5 1 0 0 1 1 1 0 PAN domain Ferric_reduct PF01794.19 EPE25446.1 - 2.2e-21 76.3 11.9 2.2e-21 76.3 11.9 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EPE25446.1 - 4.6e-18 65.8 0.0 7e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EPE25446.1 - 1.6e-09 37.8 0.0 7.6e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain Rad4 PF03835.15 EPE25447.1 - 5e-35 120.3 0.4 1.2e-34 119.1 0.4 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EPE25447.1 - 2e-29 101.8 0.0 3.6e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EPE25447.1 - 1.1e-20 73.2 0.1 2.5e-20 72.1 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EPE25447.1 - 4.4e-15 56.4 0.2 4.4e-15 56.4 0.2 2.6 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EPE25447.1 - 0.029 14.8 0.0 0.17 12.3 0.0 2.3 1 1 0 1 1 1 0 Transglutaminase-like superfamily Ion_trans_2 PF07885.16 EPE25449.1 - 1.4e-28 98.7 23.8 3.9e-15 55.6 6.2 3.3 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 EPE25449.1 - 0.00021 20.6 3.5 0.052 12.8 0.1 2.5 2 1 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 EPE25449.1 - 0.79 9.5 9.6 1.2 9.0 3.3 3.1 2 1 1 3 3 3 0 Ligand-gated ion channel DEAD PF00270.29 EPE25451.1 - 3.5e-43 147.4 0.0 6.3e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE25451.1 - 1.5e-27 96.1 0.0 4.3e-27 94.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE25451.1 - 9.1e-06 25.8 1.2 2.1e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EPE25451.1 - 0.075 13.3 0.1 0.25 11.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain Coilin_N PF15862.5 EPE25451.1 - 0.19 11.6 7.4 0.64 9.8 7.4 1.9 1 0 0 1 1 1 0 Coilin N-terminus FtsJ PF01728.19 EPE25452.1 - 1.9e-63 213.8 0.0 2.4e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Mito_carr PF00153.27 EPE25453.1 - 4e-53 177.3 4.3 3.7e-17 62.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PEX11 PF05648.14 EPE25454.1 - 1.1e-73 247.4 0.2 1.3e-73 247.2 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF2805 PF10985.8 EPE25454.1 - 0.15 12.4 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Fapy_DNA_glyco PF01149.24 EPE25455.1 - 1.1e-31 109.8 0.0 2.5e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EPE25455.1 - 1.4e-22 79.4 0.0 2.9e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain ABC2_membrane PF01061.24 EPE25456.1 - 2.7e-88 294.9 61.4 6e-47 159.8 25.1 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EPE25456.1 - 6.4e-35 120.6 0.0 3.5e-16 60.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EPE25456.1 - 1.1e-32 111.8 11.3 2.1e-29 101.3 0.0 4.0 4 0 0 4 4 4 2 CDR ABC transporter ABC_trans_N PF14510.6 EPE25456.1 - 3.1e-15 56.5 0.0 7.6e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EPE25456.1 - 1.7e-07 31.3 0.3 2.3e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EPE25456.1 - 5e-07 30.2 0.1 0.0024 18.3 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EPE25456.1 - 2.1e-06 27.5 0.1 2.2e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EPE25456.1 - 6.4e-06 26.4 0.1 0.00034 20.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EPE25456.1 - 0.00087 19.0 2.0 0.055 13.2 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EPE25456.1 - 0.0011 19.6 0.0 0.036 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EPE25456.1 - 0.0024 17.3 0.0 0.18 11.3 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EPE25456.1 - 0.0044 16.9 0.0 2.2 8.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EPE25456.1 - 0.01 15.6 0.6 0.88 9.3 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EPE25456.1 - 0.026 14.8 1.0 3.1 8.1 0.3 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EPE25456.1 - 0.026 14.9 0.2 0.57 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 EPE25456.1 - 0.05 13.5 0.0 8.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase NACHT PF05729.12 EPE25456.1 - 0.054 13.4 0.9 4.6 7.1 0.4 2.6 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 EPE25456.1 - 0.097 12.3 2.6 0.57 9.7 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EPE25456.1 - 0.11 12.5 0.2 25 5.0 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 EPE25456.1 - 7.1 5.6 50.6 4 6.4 21.9 3.0 2 1 0 2 2 2 0 ABC-2 family transporter protein RTA1 PF04479.13 EPE25458.1 - 4.9e-49 166.8 6.7 6.9e-49 166.3 6.7 1.2 1 0 0 1 1 1 1 RTA1 like protein PAS_9 PF13426.7 EPE25460.1 - 5.7e-14 52.2 0.0 9.8e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 PAS domain DUF4362 PF14275.6 EPE25460.1 - 0.038 14.3 0.0 0.057 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4362) PAS PF00989.25 EPE25460.1 - 0.04 13.9 0.0 0.25 11.3 0.0 2.2 2 1 0 2 2 2 0 PAS fold Rhamno_transf PF11316.8 EPE25460.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative rhamnosyl transferase RCR PF12273.8 EPE25461.1 - 0.00016 22.3 13.0 0.00016 22.3 13.0 2.3 1 1 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Orf78 PF06024.12 EPE25461.1 - 0.091 13.1 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Orf78 (ac78) RPN7 PF10602.9 EPE25462.1 - 4.3e-58 195.9 0.6 6.6e-58 195.2 0.6 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EPE25462.1 - 7e-13 49.0 0.0 2.6e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 PCI domain Pox_MCEL PF03291.16 EPE25463.1 - 4.3e-69 233.1 0.0 1.5e-45 155.8 0.0 2.9 1 1 1 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 EPE25463.1 - 2.8e-10 40.7 0.0 6.5e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EPE25463.1 - 7e-09 36.3 0.0 0.0071 17.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EPE25463.1 - 4.6e-06 26.6 0.0 8.7e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE25463.1 - 5.1e-06 27.0 0.0 0.1 13.2 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EPE25463.1 - 6.9e-06 25.9 0.0 0.00033 20.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EPE25463.1 - 0.0026 17.0 0.0 0.0044 16.2 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family GEMIN8 PF15348.6 EPE25463.1 - 2 8.7 10.9 0.039 14.2 3.6 1.7 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 SWIRM-assoc_2 PF16496.5 EPE25463.1 - 3.2 6.5 17.1 12 4.6 16.6 2.1 1 1 1 2 2 2 0 SWIRM-associated domain at the N-terminal DUF2961 PF11175.8 EPE25465.1 - 0.0032 17.1 0.1 0.0047 16.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) Aminotran_1_2 PF00155.21 EPE25466.1 - 8.6e-42 143.6 0.0 1.2e-41 143.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PAS_9 PF13426.7 EPE25467.1 - 1.4e-13 51.0 0.0 5.5e-13 49.1 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EPE25467.1 - 0.0028 17.6 0.0 0.01 15.8 0.0 2.0 2 0 0 2 2 2 1 PAS fold RTA1 PF04479.13 EPE25468.1 - 1.1e-63 214.5 9.0 1.8e-63 213.9 9.0 1.3 1 0 0 1 1 1 1 RTA1 like protein ATP_bind_2 PF03668.15 EPE25469.1 - 0.00082 18.8 0.0 0.028 13.7 0.0 2.1 2 0 0 2 2 2 1 P-loop ATPase protein family RNA_pol_Rpc4 PF05132.14 EPE25469.1 - 0.01 16.3 0.4 0.013 15.9 0.4 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DSPc PF00782.20 EPE25469.1 - 0.085 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain SAPS PF04499.15 EPE25469.1 - 0.21 10.3 3.8 0.29 9.9 3.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Astro_capsid_p PF12226.8 EPE25469.1 - 1.2 8.2 7.3 1.5 7.9 7.3 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ADH_zinc_N PF00107.26 EPE25470.1 - 2.3e-16 60.0 0.1 3.6e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE25470.1 - 3.7e-14 53.9 0.0 6e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE25470.1 - 3.4e-05 23.7 0.0 0.01 15.7 0.0 2.7 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 EPE25470.1 - 0.017 15.6 0.1 0.032 14.7 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_4 PF01565.23 EPE25471.1 - 2.9e-32 111.3 5.1 5.5e-32 110.4 5.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE25471.1 - 2.4e-08 34.0 0.0 4.5e-07 29.9 0.1 2.4 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.10 EPE25471.1 - 0.06 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding zf-Nse PF11789.8 EPE25472.1 - 1.7e-16 59.8 0.0 3.6e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EPE25472.1 - 0.0011 18.9 0.1 0.0022 18.0 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EPE25472.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fungal_trans_2 PF11951.8 EPE25473.1 - 1e-07 31.1 0.2 1.5e-07 30.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 EPE25474.1 - 1.2e-34 120.0 30.8 2.8e-19 69.3 10.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EPE25474.1 - 1.2e-16 60.6 43.5 9.3e-11 41.2 19.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3425 PF11905.8 EPE25475.1 - 5.7e-22 78.0 0.2 1.2e-21 76.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.25 EPE25476.1 - 9.3e-19 67.7 0.0 4.3e-17 62.2 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE25476.1 - 3e-09 36.8 0.0 1.2e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE25476.1 - 5.9e-05 23.1 0.4 0.00011 22.1 0.3 1.6 1 1 0 1 1 1 1 KR domain Nit_Regul_Hom PF10126.9 EPE25476.1 - 0.22 11.6 0.1 1.2 9.2 0.0 2.1 2 1 0 2 2 2 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII Imm7 PF15585.6 EPE25478.1 - 0.26 11.6 1.9 2.1 8.7 1.9 2.6 1 0 0 1 1 1 0 Immunity protein 7 FAM167 PF11652.8 EPE25478.1 - 0.34 11.4 3.5 0.85 10.1 0.1 3.6 2 0 0 2 2 2 0 FAM167 VSP PF03302.13 EPE25479.1 - 0.021 13.7 1.4 0.026 13.4 1.4 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4027 PF13219.6 EPE25479.1 - 0.05 13.5 0.8 0.1 12.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) NUC153 PF08159.12 EPE25480.1 - 1.2e-12 47.4 1.7 2.7e-12 46.3 1.7 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EPE25480.1 - 0.00012 22.7 0.0 1.3 10.1 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat SURF6 PF04935.12 EPE25480.1 - 0.019 14.8 3.6 0.019 14.8 3.6 2.1 2 0 0 2 2 2 0 Surfeit locus protein 6 GAPES1 PF17155.4 EPE25480.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Med13_C PF06333.12 EPE25481.1 - 8.5e-85 284.9 4.7 8.5e-85 284.9 4.7 1.9 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain PNP_UDP_1 PF01048.20 EPE25481.1 - 6.9e-30 104.0 0.0 1.1e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily Med13_N PF11597.8 EPE25481.1 - 2.7e-25 89.4 4.2 2.7e-25 89.4 4.2 2.2 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 EPE25481.1 - 3.2e-14 53.3 7.2 5.1e-08 33.0 0.1 3.8 3 1 0 4 4 4 2 MID domain of medPIWI TauD PF02668.16 EPE25482.1 - 1.1e-44 153.2 0.2 1.5e-44 152.8 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Clathrin PF00637.20 EPE25483.1 - 9e-19 67.8 1.4 9e-19 67.8 1.4 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.8 EPE25483.1 - 3.9e-16 59.0 0.4 9.5e-16 57.8 0.4 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EPE25483.1 - 4.6e-06 26.6 3.9 9.7e-06 25.5 3.9 1.6 1 0 0 1 1 1 1 Zinc-finger TPR_11 PF13414.6 EPE25483.1 - 0.00021 20.9 0.5 0.00067 19.3 0.5 1.9 1 0 0 1 1 1 1 TPR repeat zf-RING_5 PF14634.6 EPE25483.1 - 0.0023 17.8 4.7 0.0044 17.0 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EPE25483.1 - 0.0041 16.9 2.4 0.011 15.6 2.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.6 EPE25483.1 - 0.0049 17.6 1.2 9.4 7.4 0.0 3.7 3 1 1 4 4 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EPE25483.1 - 0.0057 16.7 2.3 0.026 14.6 0.2 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-RING_2 PF13639.6 EPE25483.1 - 0.0096 16.2 4.1 0.019 15.3 4.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H PF13771.6 EPE25483.1 - 0.017 15.4 1.0 0.017 15.4 1.0 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-ANAPC11 PF12861.7 EPE25483.1 - 0.019 15.0 1.8 0.045 13.8 1.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_16 PF13432.6 EPE25483.1 - 0.041 14.5 0.1 0.65 10.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat eIF3_N PF09440.10 EPE25483.1 - 0.058 13.8 3.3 0.048 14.1 0.8 2.1 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Utp13 PF08625.11 EPE25483.1 - 0.085 12.8 0.1 3.1 7.7 0.3 2.5 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain DUF4810 PF16068.5 EPE25483.1 - 0.13 12.8 0.5 17 6.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) zf-HC5HC2H_2 PF13832.6 EPE25483.1 - 0.27 11.4 3.1 0.13 12.5 0.6 1.7 2 0 0 2 2 1 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.6 EPE25483.1 - 0.46 10.6 5.4 0.49 10.5 3.9 1.9 2 0 0 2 2 1 0 RING-type zinc-finger FYVE_2 PF02318.16 EPE25483.1 - 0.69 10.1 2.1 2.1 8.6 1.0 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4 PF00097.25 EPE25483.1 - 0.75 9.7 3.9 1.6 8.7 3.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPE25483.1 - 2.6 8.4 6.6 7.2 7.0 6.6 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain TPR_1 PF00515.28 EPE25483.1 - 3.3 7.7 5.4 4.5 7.3 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat EF_assoc_2 PF08356.12 EPE25485.1 - 1.3e-33 114.8 0.0 3.2e-33 113.6 0.0 1.7 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 EPE25485.1 - 1e-28 98.7 0.6 1.9e-28 97.9 0.6 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EPE25485.1 - 1.1e-25 90.1 0.0 1.7e-16 60.3 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EPE25485.1 - 3.5e-14 53.1 0.0 3.6e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EPE25485.1 - 1.9e-08 34.4 0.0 0.00042 20.4 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 EPE25485.1 - 1.9e-06 28.1 0.1 0.14 12.2 0.0 3.2 2 1 1 3 3 3 2 Dynamin family EF-hand_7 PF13499.6 EPE25485.1 - 1e-05 25.8 0.5 0.018 15.5 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EPE25485.1 - 1.3e-05 24.4 4.5 0.045 13.3 0.8 2.7 2 0 0 2 2 2 2 EF hand AAA_29 PF13555.6 EPE25485.1 - 8.2e-05 22.3 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EPE25485.1 - 0.00011 22.6 0.0 0.11 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_6 PF13405.6 EPE25485.1 - 0.00036 20.2 4.0 0.06 13.3 0.4 2.7 2 0 0 2 2 2 2 EF-hand domain AAA_28 PF13521.6 EPE25485.1 - 0.0009 19.5 0.0 0.35 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EPE25485.1 - 0.0015 18.4 0.2 0.38 10.6 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 EPE25485.1 - 0.0016 18.0 0.0 5.3 6.5 0.0 3.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 EPE25485.1 - 0.0077 16.2 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 EPE25485.1 - 0.012 16.0 0.0 0.52 10.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 EPE25485.1 - 0.013 15.8 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EPE25485.1 - 0.02 15.4 0.0 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 ABC transporter DUF463 PF04317.12 EPE25485.1 - 0.021 13.8 0.0 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 YcjX-like family, DUF463 AAA_24 PF13479.6 EPE25485.1 - 0.022 14.5 0.0 0.47 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EPE25485.1 - 0.031 14.8 0.1 1.4 9.4 0.2 3.2 2 1 0 2 2 2 0 AAA domain EF-hand_8 PF13833.6 EPE25485.1 - 0.032 14.1 3.3 2 8.3 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain pair AAA_25 PF13481.6 EPE25485.1 - 0.094 12.3 0.1 15 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EPE25485.1 - 0.12 12.6 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain EF-hand_5 PF13202.6 EPE25485.1 - 0.13 11.8 6.6 1.1 8.8 2.8 2.7 2 0 0 2 2 2 0 EF hand WD40 PF00400.32 EPE25486.1 - 1e-11 45.2 17.1 0.00018 22.2 0.2 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE25486.1 - 4.4e-09 36.5 0.0 0.015 15.6 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE25486.1 - 0.0013 18.7 0.0 0.0084 16.0 0.0 1.9 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EPE25486.1 - 0.0082 16.1 0.0 2.5 8.1 0.0 2.9 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EPE25486.1 - 0.0086 14.1 0.0 0.012 13.6 0.0 1.3 1 0 0 1 1 1 1 IKI3 family Cytochrom_D1 PF02239.16 EPE25486.1 - 0.018 13.6 0.0 0.036 12.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain VID27 PF08553.10 EPE25486.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain NAR2 PF16974.5 EPE25486.1 - 0.21 11.0 0.3 0.57 9.6 0.1 1.7 2 0 0 2 2 2 0 High-affinity nitrate transporter accessory Band_7 PF01145.25 EPE25488.1 - 3.2e-16 59.9 0.0 3.2e-16 59.9 0.0 3.0 2 2 0 2 2 2 1 SPFH domain / Band 7 family RPAP1_N PF08621.10 EPE25488.1 - 0.082 12.7 1.3 0.28 11.0 0.2 2.5 2 0 0 2 2 2 0 RPAP1-like, N-terminal FAM216B PF15107.6 EPE25488.1 - 0.095 12.6 0.0 5.7 6.9 0.0 2.7 1 1 1 2 2 2 0 FAM216B protein family DUF3072 PF11272.8 EPE25488.1 - 0.14 12.1 0.0 0.14 12.1 0.0 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF3072) PhyH PF05721.13 EPE25489.1 - 1.7e-05 25.2 0.0 0.00012 22.4 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2433 PF10360.9 EPE25490.1 - 1.1e-49 167.7 0.0 1.8e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.7 EPE25490.1 - 0.00088 19.5 0.0 0.0028 17.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EPE25490.1 - 0.00091 19.8 0.0 0.002 18.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PAT1 PF09770.9 EPE25490.1 - 3.8 5.7 4.8 5.2 5.2 4.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ubie_methyltran PF01209.18 EPE25491.1 - 6.7e-80 267.8 0.0 8.5e-80 267.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EPE25491.1 - 3.7e-15 56.4 0.0 1.2e-14 54.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE25491.1 - 1.4e-13 51.2 0.0 5.2e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE25491.1 - 1.3e-12 47.8 0.0 1.8e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE25491.1 - 5.6e-11 43.1 0.0 9.4e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE25491.1 - 1.3e-07 31.6 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Bac_luciferase PF00296.20 EPE25492.1 - 6.1e-61 206.6 0.1 7e-61 206.4 0.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase MOSC PF03473.17 EPE25492.1 - 0.05 13.6 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 MOSC domain His_Phos_1 PF00300.22 EPE25493.1 - 5.7e-16 58.8 0.3 9.3e-16 58.1 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Gly_transf_sug PF04488.15 EPE25495.1 - 1.1e-09 38.7 0.0 2.5e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EPE25495.1 - 0.06 12.6 0.1 0.099 11.9 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain zf-CCCH PF00642.24 EPE25496.1 - 3.6e-06 26.7 2.9 7.8e-06 25.7 2.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EPE25496.1 - 1.8e-05 24.4 2.0 6.5e-05 22.6 2.0 2.0 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EPE25496.1 - 0.00016 21.6 3.7 0.00016 21.6 3.7 1.9 2 0 0 2 2 2 1 Zinc finger domain Cpn60_TCP1 PF00118.24 EPE25497.1 - 3.2e-159 530.7 7.9 3.6e-159 530.5 7.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 EPE25497.1 - 0.28 11.4 3.3 15 5.8 0.1 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain Pkinase PF00069.25 EPE25498.1 - 1.4e-72 244.3 0.0 1.8e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE25498.1 - 1.1e-45 155.9 0.0 1.7e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EPE25498.1 - 6.9e-22 77.6 0.2 2.2e-21 76.0 0.2 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 EPE25498.1 - 4e-07 29.7 0.0 6.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EPE25498.1 - 2.6e-06 26.5 0.0 4.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EPE25498.1 - 0.0063 15.5 0.1 0.0063 15.5 0.1 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EPE25498.1 - 0.038 13.3 0.2 0.27 10.6 0.1 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EPE25498.1 - 0.13 11.8 0.1 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EPE25498.1 - 0.15 11.9 1.6 0.35 10.8 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family KH_1 PF00013.29 EPE25499.1 - 2.2e-103 338.1 27.0 4.4e-15 55.3 1.5 12.0 11 1 0 11 11 11 9 KH domain SLS PF14611.6 EPE25499.1 - 2.2e-12 47.3 5.3 0.00099 19.0 0.2 7.3 5 3 3 8 8 8 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 EPE25499.1 - 9e-12 44.7 26.7 0.0033 17.2 0.4 8.1 6 1 0 7 7 7 5 KH domain KH_4 PF13083.6 EPE25499.1 - 1.1e-05 25.2 12.5 0.26 11.2 0.1 7.4 8 0 0 8 8 8 2 KH domain KH_5 PF13184.6 EPE25499.1 - 0.012 15.7 16.7 0.47 10.6 0.0 6.6 8 0 0 8 8 8 0 NusA-like KH domain YbbR PF07949.12 EPE25499.1 - 1.8 9.0 12.8 6.3 7.2 0.0 5.9 6 1 1 7 7 7 0 YbbR-like protein ExbD PF02472.16 EPE25499.1 - 2.3 8.4 9.1 1.3 9.2 0.1 3.7 4 1 0 4 4 4 0 Biopolymer transport protein ExbD/TolR NUDIX PF00293.28 EPE25500.1 - 2.7e-13 50.1 0.6 5e-13 49.2 0.6 1.4 1 1 0 1 1 1 1 NUDIX domain Chromo_shadow PF01393.19 EPE25501.1 - 7.2e-19 67.6 0.8 2.8e-17 62.5 0.0 2.4 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 EPE25501.1 - 3e-12 46.2 1.0 8.5e-12 44.8 0.4 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DNA_pol_phi PF04931.13 EPE25501.1 - 3.4 5.7 8.2 4.1 5.4 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAD_binding_3 PF01494.19 EPE25502.1 - 5.6e-23 81.8 0.0 8.2e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EPE25502.1 - 2.6e-07 30.3 0.1 0.00017 21.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EPE25502.1 - 1.6e-06 27.6 0.1 0.04 13.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE25502.1 - 5.1e-06 25.8 0.1 0.051 12.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPE25502.1 - 0.00074 19.7 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE25502.1 - 0.0049 16.5 0.0 0.94 9.0 0.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPE25502.1 - 0.0086 15.4 0.0 0.65 9.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE25502.1 - 0.0096 16.5 0.7 0.18 12.3 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 EPE25503.1 - 4.5e-60 203.1 1.8 7.5e-60 202.4 1.8 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE25503.1 - 1.6e-51 174.6 1.2 2.6e-51 173.8 1.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE25503.1 - 4.7e-13 49.4 0.2 6.5e-13 49.0 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE25503.1 - 0.00065 19.2 0.1 0.0012 18.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EPE25503.1 - 0.0016 17.6 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PA PF02225.22 EPE25503.1 - 0.0044 17.0 4.9 0.0077 16.2 0.1 3.1 2 1 2 4 4 4 1 PA domain GDP_Man_Dehyd PF16363.5 EPE25503.1 - 0.0069 15.8 0.0 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Acetyltransf_1 PF00583.25 EPE25504.1 - 3.2e-10 40.3 0.0 5.4e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE25504.1 - 9.5e-09 35.6 0.2 4.8e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPE25504.1 - 5.6e-06 26.3 0.0 6.4e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPE25504.1 - 0.0021 18.2 0.0 0.042 13.9 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain ARID PF01388.21 EPE25505.1 - 2.2e-20 73.1 0.1 6.1e-20 71.7 0.1 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain RFX_DNA_binding PF02257.15 EPE25505.1 - 0.0025 18.4 0.0 0.0073 16.9 0.0 1.8 2 0 0 2 2 2 1 RFX DNA-binding domain Aspzincin_M35 PF14521.6 EPE25506.1 - 0.004 17.7 0.3 0.0082 16.7 0.3 1.6 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Meiotic_rec114 PF03525.14 EPE25507.1 - 0.084 11.8 2.2 0.34 9.8 0.0 2.7 2 1 1 3 3 3 0 Meiotic recombination protein rec114 SelR PF01641.18 EPE25508.1 - 3.3e-49 166.0 0.2 4.4e-49 165.6 0.2 1.2 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 EPE25508.1 - 0.0092 15.7 0.2 0.14 11.9 0.0 2.2 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein GFA PF04828.14 EPE25508.1 - 0.021 15.2 0.4 2 8.8 0.0 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 EPE25508.1 - 0.025 14.6 0.4 3.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon MCM_OB PF17207.3 EPE25508.1 - 0.072 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 MCM OB domain Yippee-Mis18 PF03226.14 EPE25508.1 - 0.11 12.7 0.4 0.29 11.4 0.4 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.12 EPE25508.1 - 0.11 12.0 1.4 1.2 8.7 0.2 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding ArfGap PF01412.18 EPE25509.1 - 1.4e-40 138.0 0.3 2.1e-40 137.5 0.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF4349 PF14257.6 EPE25510.1 - 0.096 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Ysc84 PF04366.12 EPE25511.1 - 3.5e-41 140.0 0.3 5.5e-41 139.3 0.3 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EPE25511.1 - 4e-13 48.7 0.1 1.3e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EPE25511.1 - 9.5e-13 47.6 0.1 3.3e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EPE25511.1 - 1.5e-11 43.9 0.0 3.8e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain DUF3104 PF11302.8 EPE25511.1 - 0.16 11.7 0.1 0.39 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Wbp11 PF09429.10 EPE25512.1 - 1.1e-23 83.4 13.4 1.1e-23 83.4 13.4 2.2 2 0 0 2 2 2 1 WW domain binding protein 11 Hrs_helical PF12210.8 EPE25512.1 - 2.9 8.5 5.5 5.9 7.5 0.3 3.0 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate FSH1 PF03959.13 EPE25513.1 - 8.2e-26 91.0 0.0 1.1e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EPE25513.1 - 0.0041 17.0 0.0 0.026 14.4 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase ADH_zinc_N PF00107.26 EPE25514.1 - 1.1e-22 80.4 0.1 1.7e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE25514.1 - 4.6e-16 58.6 0.9 8.1e-16 57.9 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EPE25514.1 - 0.0014 19.7 0.0 0.0024 18.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EPE25514.1 - 0.0048 16.3 0.1 0.0088 15.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EPE25514.1 - 0.011 15.0 0.2 0.024 14.0 0.1 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 EPE25514.1 - 0.028 15.1 0.0 0.073 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.18 EPE25514.1 - 0.089 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain DUF2183 PF09949.9 EPE25515.1 - 8.4e-19 67.7 0.1 1.7e-18 66.7 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) RTP1_C1 PF10363.9 EPE25516.1 - 1.5e-29 102.4 0.4 2.4e-28 98.5 0.2 2.9 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EPE25516.1 - 3.8e-11 42.5 0.4 9.4e-11 41.2 0.4 1.6 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 Cnd1 PF12717.7 EPE25516.1 - 0.0015 18.6 1.8 0.024 14.7 0.0 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.6 EPE25516.1 - 0.074 12.7 1.1 3.6 7.2 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4042) DUF1184 PF06683.11 EPE25517.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) WAC_Acf1_DNA_bd PF10537.9 EPE25518.1 - 0.0021 18.6 0.1 0.0087 16.6 0.1 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal zf-nanos PF05741.13 EPE25518.1 - 9.3 6.6 7.5 3.1e+02 1.7 5.8 3.4 1 1 1 2 2 2 0 Nanos RNA binding domain ApbA PF02558.16 EPE25520.1 - 2e-26 92.5 0.0 2.8e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EPE25520.1 - 6.4e-24 84.5 0.0 9.4e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Activator-TraM PF11657.8 EPE25521.1 - 0.074 12.9 0.7 0.12 12.2 0.7 1.3 1 0 0 1 1 1 0 Transcriptional activator TraM FliJ PF02050.16 EPE25521.1 - 0.15 12.3 2.9 0.18 12.1 1.6 1.7 1 1 1 2 2 2 0 Flagellar FliJ protein Agglutinin PF07468.11 EPE25521.1 - 0.16 12.2 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Agglutinin domain YfhD PF14151.6 EPE25523.1 - 0.084 13.0 0.4 0.2 11.9 0.4 1.5 1 0 0 1 1 1 0 YfhD-like protein BRI3BP PF14965.6 EPE25523.1 - 1.2 8.6 6.3 2 7.9 6.3 1.3 1 0 0 1 1 1 0 Negative regulator of p53/TP53 DUF1700 PF08006.11 EPE25523.1 - 4.5 6.8 7.7 7.5 6.0 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Robl_LC7 PF03259.17 EPE25526.1 - 8.9e-11 41.4 0.1 4.1e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.8 EPE25527.1 - 5.7e-27 94.3 0.1 5.7e-27 94.3 0.1 2.4 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Pyrid_oxidase_2 PF13883.6 EPE25528.1 - 1.3e-46 158.7 0.0 1.6e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ribosomal_S30 PF04758.14 EPE25529.1 - 1.2e-29 102.3 8.0 1.3e-29 102.2 8.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Rpr2 PF04032.16 EPE25530.1 - 3.3e-19 68.9 2.6 1.4e-18 66.9 2.6 1.8 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DEAD PF00270.29 EPE25531.1 - 3.6e-37 127.8 0.1 7e-37 126.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE25531.1 - 4e-25 88.3 0.1 2.2e-23 82.7 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE25531.1 - 2.8e-10 40.5 0.0 6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4844 PF16133.5 EPE25531.1 - 0.051 14.1 0.7 0.11 13.0 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) DASH_Dam1 PF08653.10 EPE25532.1 - 0.082 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dam1 DUF4326 PF14216.6 EPE25532.1 - 0.098 13.4 0.0 0.14 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4326) ECH_1 PF00378.20 EPE25534.1 - 1.5e-33 116.2 0.0 2.1e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPE25534.1 - 2.5e-14 53.5 0.0 2.8e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Glyoxalase_3 PF13468.6 EPE25535.1 - 6.2e-06 26.4 0.0 7.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 EPE25535.1 - 0.00022 21.5 0.0 0.00066 19.9 0.0 1.7 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF302 PF03625.14 EPE25536.1 - 1.6e-07 31.1 0.0 2.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF302 ADH_N_2 PF16884.5 EPE25537.1 - 5.4e-21 74.5 0.0 9.9e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EPE25537.1 - 1.5e-16 60.6 0.0 2.1e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE25537.1 - 6.9e-11 43.3 0.0 1.4e-10 42.3 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glyco_hydro_7 PF00840.20 EPE25538.1 - 3.8e-204 678.4 13.8 4.3e-204 678.2 13.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 SpdB PF05122.13 EPE25538.1 - 1.8 8.8 5.1 3.2 7.9 0.6 2.8 2 0 0 2 2 2 0 Mobile element transfer protein BUD22 PF09073.10 EPE25539.1 - 2e-98 330.6 22.1 3.2e-98 329.9 22.1 1.3 1 0 0 1 1 1 1 BUD22 WSC PF01822.19 EPE25540.1 - 3.4e-14 52.8 4.4 7.1e-14 51.8 4.4 1.6 1 0 0 1 1 1 1 WSC domain Opiods_neuropep PF01160.18 EPE25540.1 - 0.11 12.6 5.6 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide GATA PF00320.27 EPE25543.1 - 4.4e-16 58.2 2.5 9.2e-16 57.2 2.5 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 EPE25543.1 - 1.3e-12 47.3 2.8 1.3e-12 47.3 2.8 1.9 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) AreA_N PF07573.11 EPE25543.1 - 0.019 15.6 6.7 0.019 15.6 6.7 3.9 3 0 0 3 3 3 0 Nitrogen regulatory protein AreA N terminus POP1 PF06978.11 EPE25544.1 - 2.6e-77 259.5 10.8 4.3e-77 258.7 10.8 1.4 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EPE25544.1 - 1.7e-32 111.6 0.2 6.8e-32 109.7 0.2 2.0 2 0 0 2 2 2 1 POPLD (NUC188) domain HgmA PF04209.13 EPE25545.1 - 1.2e-170 567.9 0.3 1.4e-170 567.7 0.3 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase HIM1 PF08732.10 EPE25546.1 - 4.4e-09 36.1 0.0 6.8e-08 32.2 0.0 1.9 1 1 1 2 2 2 1 HIM1 NAD_binding_10 PF13460.6 EPE25546.1 - 1.9e-06 27.9 0.0 2.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE25546.1 - 3.8e-05 23.3 0.0 0.00014 21.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EPE25546.1 - 0.00086 19.7 0.1 0.0021 18.5 0.0 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 EPE25546.1 - 0.01 15.4 0.0 0.25 10.9 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 EPE25546.1 - 0.018 14.2 0.0 1.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein DUF1471 PF07338.13 EPE25546.1 - 0.087 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) HET PF06985.11 EPE25547.1 - 9.2e-25 87.7 0.0 1.5e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_1 PF00667.20 EPE25548.1 - 2.1e-63 213.8 0.0 3.5e-63 213.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EPE25548.1 - 1.8e-09 38.2 0.0 4.8e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 EPE25548.1 - 4.6e-09 36.5 0.1 1.3e-08 35.1 0.1 1.8 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II POR PF01558.18 EPE25548.1 - 6.9e-07 29.5 0.0 1.8e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.20 EPE25548.1 - 8.3e-05 22.5 0.1 0.00023 21.0 0.1 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain SH3_15 PF18346.1 EPE25548.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Mind bomb SH3 repeat domain Glyco_hydro_61 PF03443.14 EPE25549.1 - 1.2e-56 192.0 0.0 1.4e-56 191.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PilJ PF13675.6 EPE25550.1 - 0.31 11.1 5.2 0.088 12.8 0.6 2.5 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term FYVE_2 PF02318.16 EPE25550.1 - 0.78 10.0 4.1 2.1 8.6 0.3 3.0 3 0 0 3 3 3 0 FYVE-type zinc finger Chal_sti_synt_C PF02797.15 EPE25552.1 - 1.7e-22 80.1 0.0 3.4e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 EPE25552.1 - 8e-20 71.2 0.2 1.4e-19 70.5 0.2 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain FAE1_CUT1_RppA PF08392.12 EPE25552.1 - 2.3e-05 23.8 0.0 3.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 EPE25552.1 - 2.6e-05 24.3 0.0 0.001 19.2 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EPE25552.1 - 0.018 14.9 0.1 0.049 13.5 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF4142 PF13628.6 EPE25553.1 - 0.0031 17.8 1.9 0.0047 17.2 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4142) VSG_B PF13206.6 EPE25553.1 - 0.046 13.0 0.7 0.072 12.3 0.7 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain PDEase_I_N PF08499.12 EPE25553.1 - 0.081 12.8 0.3 0.55 10.1 0.1 2.4 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal UPF0184 PF03670.13 EPE25553.1 - 4.6 7.7 8.8 13 6.2 0.7 3.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) TRAUB PF08164.12 EPE25554.1 - 2.4e-29 101.7 0.5 2.5e-28 98.4 0.0 3.0 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EPE25554.1 - 4.3e-26 92.3 3.2 4.3e-26 92.3 3.2 2.9 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor Protamine_P2 PF00841.19 EPE25554.1 - 0.09 13.3 1.4 0.33 11.5 1.4 1.9 1 0 0 1 1 1 0 Sperm histone P2 ParA PF10609.9 EPE25555.1 - 2.4e-95 318.7 0.3 2.8e-95 318.5 0.3 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EPE25555.1 - 6.5e-12 45.6 0.0 2.6e-11 43.7 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EPE25555.1 - 7e-10 39.1 0.4 1.5e-07 31.5 0.1 2.1 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 EPE25555.1 - 1.8e-05 24.2 0.1 2.7e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 EPE25555.1 - 0.00087 18.9 0.1 0.0021 17.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 EPE25555.1 - 0.0011 18.2 0.8 0.04 13.1 0.2 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 EPE25555.1 - 0.039 13.4 0.0 0.59 9.5 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 EPE25555.1 - 0.042 13.3 0.8 0.15 11.5 0.3 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 EPE25555.1 - 0.052 13.4 0.2 0.53 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 EPE25555.1 - 0.11 12.2 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zn_Tnp_IS1595 PF12760.7 EPE25555.1 - 0.13 12.2 0.3 0.24 11.4 0.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DegS PF05384.11 EPE25556.1 - 0.00012 21.6 1.9 0.00012 21.6 1.9 2.4 2 0 0 2 2 2 1 Sensor protein DegS Tht1 PF04163.12 EPE25556.1 - 0.014 14.2 5.9 0.033 13.0 4.9 1.8 1 1 0 1 1 1 0 Tht1-like nuclear fusion protein HD_assoc PF13286.6 EPE25556.1 - 0.026 15.1 4.9 1.7 9.2 0.1 3.3 4 0 0 4 4 4 0 Phosphohydrolase-associated domain DUF3450 PF11932.8 EPE25556.1 - 1.2 8.4 11.2 0.13 11.5 5.7 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF2937 PF11157.8 EPE25556.1 - 4.4 7.0 10.4 16 5.2 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) EF-G-binding_N PF07299.11 EPE25557.1 - 0.29 11.7 1.3 1.4 9.5 0.0 2.5 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal HEAT_EZ PF13513.6 EPE25559.1 - 1.9e-21 76.1 17.3 1.7e-06 28.4 0.1 10.0 9 1 2 11 11 10 5 HEAT-like repeat HEAT PF02985.22 EPE25559.1 - 2e-16 58.7 10.2 0.0044 17.2 0.1 10.7 11 0 0 11 11 10 3 HEAT repeat HEAT_2 PF13646.6 EPE25559.1 - 6.6e-16 58.5 11.0 0.047 14.1 0.0 8.1 5 2 3 8 8 8 6 HEAT repeats IBN_N PF03810.19 EPE25559.1 - 1.7e-08 34.2 0.5 2.2e-07 30.7 0.1 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 EPE25559.1 - 3.5e-08 33.9 0.0 0.3 11.7 0.0 6.8 6 3 1 7 7 6 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 EPE25559.1 - 6.8e-07 28.7 3.8 0.19 10.8 0.1 4.4 2 1 3 5 5 5 2 Interferon-related developmental regulator (IFRD) Arm PF00514.23 EPE25559.1 - 1.3e-06 28.2 10.0 0.034 14.2 0.0 8.4 10 0 0 10 10 9 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EPE25559.1 - 5.1e-06 25.3 0.1 0.0043 15.7 0.0 3.7 3 1 0 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.8 EPE25559.1 - 7.4e-05 22.4 1.7 0.4 10.2 0.0 5.0 5 1 2 7 7 7 1 CLASP N terminal Cnd1 PF12717.7 EPE25559.1 - 7.9e-05 22.7 1.1 9 6.3 0.1 5.2 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 EPE25559.1 - 0.00061 20.0 0.1 0.0098 16.0 0.0 3.0 3 1 0 3 3 3 1 Parkin co-regulated protein Importin_rep_4 PF18808.1 EPE25559.1 - 0.0026 18.0 5.6 0.093 13.0 0.2 4.6 4 0 0 4 4 4 1 Importin repeat MMS19_C PF12460.8 EPE25559.1 - 0.0033 16.6 9.8 0.23 10.5 0.1 4.5 5 0 0 5 5 5 2 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 EPE25559.1 - 0.012 15.8 0.4 6.2 7.0 0.0 4.7 6 0 0 6 6 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4211 PF13926.6 EPE25559.1 - 0.095 12.7 0.3 21 5.1 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4211) HEAT_PBS PF03130.16 EPE25559.1 - 4 8.4 8.3 43 5.2 0.0 5.1 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Acetyltransf_1 PF00583.25 EPE25560.1 - 2e-07 31.3 0.0 2.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE25560.1 - 1.4e-05 25.4 0.0 2.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPE25560.1 - 9.8e-05 22.3 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GYF_2 PF14237.6 EPE25560.1 - 0.086 12.7 0.3 10 6.0 0.1 2.8 3 0 0 3 3 3 0 GYF domain 2 PLRV_ORF5 PF01690.17 EPE25561.1 - 3.9 6.1 6.6 0.51 9.0 0.0 2.0 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein Aldo_ket_red PF00248.21 EPE25562.1 - 1.7e-36 125.9 0.0 4.3e-34 118.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family eRF1_1 PF03463.15 EPE25563.1 - 3e-49 166.3 0.1 4.8e-49 165.7 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 EPE25563.1 - 4.5e-21 75.5 0.0 6.4e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EPE25563.1 - 1.8e-20 73.5 0.0 3.6e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 PTPA PF03095.15 EPE25565.1 - 1e-116 389.6 0.0 1.2e-116 389.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Myc-LZ PF02344.15 EPE25567.1 - 0.33 11.1 19.1 10 6.3 0.2 7.9 8 0 0 8 8 8 0 Myc leucine zipper domain Spc7 PF08317.11 EPE25567.1 - 0.84 8.5 168.0 0.081 11.8 12.0 8.1 1 1 6 8 8 8 0 Spc7 kinetochore protein DUF960 PF06124.11 EPE25568.1 - 0.047 14.3 0.3 19 6.0 0.0 3.2 3 0 0 3 3 3 0 Staphylococcal protein of unknown function (DUF960) PEPCK_ATP PF01293.20 EPE25570.1 - 3.7e-213 708.4 0.0 4.6e-213 708.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase MRFAP1 PF15155.6 EPE25570.1 - 0.2 12.2 0.0 0.41 11.2 0.0 1.5 1 0 0 1 1 1 0 MORF4 family-associated protein1 UQ_con PF00179.26 EPE25572.1 - 1.6e-35 121.8 0.1 2.1e-35 121.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pantoate_transf PF02548.15 EPE25573.1 - 1.9e-104 348.7 0.3 2.2e-104 348.4 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EPE25573.1 - 3.2e-07 30.0 0.2 4.7e-07 29.5 0.2 1.4 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase APG12 PF04110.13 EPE25574.1 - 5e-27 94.1 0.0 5.9e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EPE25574.1 - 4.1e-05 23.7 0.0 4.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Peptidase_M24 PF00557.24 EPE25575.1 - 4.5e-51 173.5 0.0 7.1e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EPE25575.1 - 4.2e-38 129.9 0.0 8.4e-38 128.9 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.10 EPE25576.1 - 2.9e-43 147.1 4.6 4.1e-43 146.6 0.0 3.2 3 0 0 3 3 3 1 Dfp1/Him1, central region zf-DBF PF07535.12 EPE25576.1 - 1.9e-21 75.9 1.0 4e-21 74.8 1.0 1.6 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 EPE25576.1 - 0.0079 16.1 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain zf-C2H2_2 PF12756.7 EPE25576.1 - 0.022 15.1 1.6 0.056 13.8 1.6 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Abhydrolase_6 PF12697.7 EPE25578.1 - 2.5e-15 57.7 0.0 3e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EPE25578.1 - 0.0012 18.7 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE25578.1 - 0.0024 17.2 0.0 0.41 9.9 0.0 2.6 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 EPE25578.1 - 0.0075 15.3 0.0 0.014 14.4 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase Peptidase_S9 PF00326.21 EPE25578.1 - 0.055 12.9 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EPE25578.1 - 0.068 12.1 0.0 0.14 11.0 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme UCH_1 PF13423.6 EPE25579.1 - 5.2e-95 318.7 0.0 7.7e-95 318.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EPE25579.1 - 1.4e-21 77.7 0.0 3.2e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Exonuclease eIF2A PF08662.11 EPE25579.1 - 0.019 14.8 0.2 0.068 13.0 0.1 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PFO_beta_C PF12367.8 EPE25579.1 - 0.066 13.4 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal adh_short PF00106.25 EPE25580.1 - 3.4e-18 65.8 0.0 6.1e-17 61.7 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EPE25580.1 - 3.2e-08 33.7 0.1 4.8e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EPE25580.1 - 2.2e-07 30.7 0.0 3.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cyclase PF04199.13 EPE25580.1 - 0.091 13.0 0.0 0.23 11.7 0.0 1.7 1 1 0 1 1 1 0 Putative cyclase Zn_clus PF00172.18 EPE25581.1 - 0.0011 19.0 9.4 0.0025 17.9 9.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE25581.1 - 0.078 12.0 1.3 0.52 9.3 0.0 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain MFS_1 PF07690.16 EPE25582.1 - 2.9e-45 154.7 47.3 2.9e-45 154.7 47.3 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE25582.1 - 6.9e-12 44.6 19.4 1.1e-11 44.0 19.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) IncE PF17627.2 EPE25582.1 - 6.7 6.7 7.4 1.7 8.7 0.5 3.2 3 0 0 3 3 3 0 Inclusion membrane protein E Pkinase PF00069.25 EPE25583.1 - 7e-33 114.1 0.0 2.6e-16 59.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE25583.1 - 1.1e-14 54.3 0.0 2.9e-07 30.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase A1_Propeptide PF07966.12 EPE25583.1 - 0.087 12.7 0.5 0.3 11.0 0.5 1.9 1 0 0 1 1 1 0 A1 Propeptide SOG2 PF10428.9 EPE25583.1 - 4.4 6.4 10.9 6.3 5.9 10.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PAP1 PF08601.10 EPE25584.1 - 1.9e-107 360.3 18.0 1.9e-107 360.3 18.0 2.5 3 0 0 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.21 EPE25584.1 - 1.2e-08 34.9 10.6 2.5e-08 33.9 10.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 EPE25584.1 - 0.0037 17.0 5.5 0.0037 17.0 5.5 1.6 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 EPE25584.1 - 0.016 15.3 10.8 0.051 13.7 10.8 1.8 1 1 0 1 1 1 0 Basic region leucine zipper Cluap1 PF10234.9 EPE25584.1 - 0.022 14.2 2.9 0.038 13.4 2.9 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 Nop53 PF07767.11 EPE25584.1 - 0.024 14.0 12.6 0.04 13.3 12.6 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) bZIP_Maf PF03131.17 EPE25584.1 - 0.064 13.8 8.5 0.13 12.8 8.5 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor HAUS-augmin3 PF14932.6 EPE25584.1 - 0.087 12.4 4.2 0.16 11.6 4.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF5320 PF17253.2 EPE25584.1 - 0.16 13.1 1.0 0.47 11.5 1.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5320) FlaC_arch PF05377.11 EPE25584.1 - 0.48 10.9 1.7 1.1 9.6 1.7 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 EPE25584.1 - 0.63 10.1 5.5 0.27 11.3 2.9 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TolA_bind_tri PF16331.5 EPE25584.1 - 1.5 9.0 6.1 0.11 12.7 0.9 1.8 2 0 0 2 2 2 0 TolA binding protein trimerisation JIP_LZII PF16471.5 EPE25584.1 - 1.5 9.0 5.7 2.4 8.4 3.1 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II CDC45 PF02724.14 EPE25584.1 - 1.8 6.8 11.1 2.5 6.3 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-H PF05837.12 EPE25584.1 - 9 6.8 8.6 3.3 8.1 5.2 2.1 2 0 0 2 2 1 0 Centromere protein H (CENP-H) BSD PF03909.17 EPE25585.1 - 5.1e-18 64.8 1.4 1e-17 63.8 1.4 1.6 1 0 0 1 1 1 1 BSD domain WGG PF10273.9 EPE25586.1 - 2.3e-29 101.9 0.8 3.7e-29 101.2 0.8 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 NPDC1 PF06809.11 EPE25586.1 - 0.076 12.1 0.6 0.097 11.7 0.6 1.1 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) RRP7 PF12923.7 EPE25586.1 - 2.6 8.2 7.5 2.5 8.2 0.1 2.3 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Abhydrolase_3 PF07859.13 EPE25587.1 - 6.1e-42 143.9 0.0 9.1e-32 110.6 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EPE25587.1 - 6.3e-14 51.6 0.0 3e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 EPE25587.1 - 0.00051 19.0 0.3 0.0031 16.5 0.3 2.0 1 1 0 1 1 1 1 Carboxylesterase family Cellulase PF00150.18 EPE25588.1 - 1.4e-10 41.1 0.7 1.4e-10 41.1 0.7 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) ODV-E18 PF10717.9 EPE25588.1 - 0.0028 17.5 0.2 0.009 15.9 0.2 1.9 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 CcmE PF03100.15 EPE25588.1 - 0.0056 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 CcmE DUF3357 PF11837.8 EPE25588.1 - 0.024 15.1 0.8 0.058 13.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) LAP1C PF05609.12 EPE25588.1 - 0.16 11.0 2.5 0.24 10.5 2.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4064 PF13273.6 EPE25588.1 - 0.42 10.9 3.2 0.89 9.9 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) EphA2_TM PF14575.6 EPE25588.1 - 1.1 10.2 0.0 1.1 10.2 0.0 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Transket_pyr PF02779.24 EPE25589.1 - 3e-41 141.0 0.0 4.1e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EPE25589.1 - 7.6e-30 103.3 0.0 1.5e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EPE25589.1 - 0.0062 16.8 0.0 0.017 15.4 0.0 1.7 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II F-actin_cap_A PF01267.17 EPE25590.1 - 5.2e-99 331.0 0.0 5.9e-99 330.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit ACAS_N PF16177.5 EPE25590.1 - 0.034 14.1 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus PBP5_C PF07943.13 EPE25590.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Penicillin-binding protein 5, C-terminal domain Cyt-b5 PF00173.28 EPE25591.1 - 2.3e-21 75.7 0.2 3.3e-21 75.2 0.2 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4366 PF14283.6 EPE25591.1 - 0.084 12.9 0.0 0.095 12.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) zf-RING_2 PF13639.6 EPE25592.1 - 7.5e-09 35.8 2.1 1.1e-08 35.3 2.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EPE25592.1 - 2.3e-06 27.8 3.4 2.4e-05 24.5 3.3 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EPE25592.1 - 4.8e-05 23.3 0.8 8.1e-05 22.6 0.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EPE25592.1 - 0.00031 20.7 4.7 0.00051 20.0 4.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EPE25592.1 - 0.0015 18.2 1.6 0.0026 17.4 1.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EPE25592.1 - 0.0074 16.1 1.7 0.044 13.7 1.4 2.0 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE25592.1 - 0.015 15.2 1.7 0.026 14.4 1.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE25592.1 - 0.016 15.1 5.1 0.075 12.9 5.2 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE25592.1 - 0.069 13.0 2.7 1.3 9.0 0.2 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 MFS_1 PF07690.16 EPE25593.1 - 3e-51 174.4 33.9 1.9e-49 168.5 36.1 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4245 PF14030.6 EPE25593.1 - 0.17 11.9 2.7 0.73 9.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4245) Ribosomal_S5_C PF03719.15 EPE25594.1 - 7.6e-23 79.8 0.7 2e-22 78.4 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EPE25594.1 - 7.8e-18 64.2 0.0 1.5e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.10 EPE25595.1 - 1.9e-32 111.2 0.7 2.3e-32 110.9 0.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Vac_Fusion PF02346.16 EPE25595.1 - 0.14 11.8 0.1 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 FBPase_2 PF06874.11 EPE25595.1 - 0.17 10.2 0.1 0.2 9.9 0.1 1.1 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase Baculo_gp64 PF03273.13 EPE25595.1 - 0.21 10.3 0.0 0.23 10.2 0.0 1.0 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family Zn_clus PF00172.18 EPE25596.1 - 1.4e-08 34.7 7.3 2.5e-08 33.9 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE25596.1 - 3.4e-08 32.8 0.0 6.3e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 EPE25597.1 - 1.3e-26 93.3 25.7 2.1e-26 92.7 25.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EPE25597.1 - 1.4e-24 87.2 0.1 2e-24 86.6 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EPE25597.1 - 6.4e-07 29.5 0.1 0.00044 20.2 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EPE25597.1 - 7e-06 26.0 0.2 0.00016 21.6 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Rad17 PF03215.15 EPE25597.1 - 0.00028 20.9 0.0 0.00056 19.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain SMC_N PF02463.19 EPE25597.1 - 0.0003 20.3 0.3 0.00059 19.3 0.3 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EPE25597.1 - 0.0004 20.8 0.0 0.00074 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EPE25597.1 - 0.00045 19.8 0.1 0.00092 18.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EPE25597.1 - 0.00045 20.6 0.1 0.014 15.8 0.2 2.5 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPE25597.1 - 0.0083 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EPE25597.1 - 0.0084 16.4 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EPE25597.1 - 0.018 15.1 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.18 EPE25597.1 - 0.084 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 EPE25597.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EPE25597.1 - 0.13 12.3 0.0 0.47 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EPE25597.1 - 0.15 12.6 0.0 0.35 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF423 PF04241.15 EPE25597.1 - 0.25 11.6 1.6 16 5.8 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF423) AAA_13 PF13166.6 EPE25597.1 - 0.27 9.8 0.2 0.44 9.1 0.2 1.2 1 0 0 1 1 1 0 AAA domain adh_short_C2 PF13561.6 EPE25598.1 - 7.3e-31 107.5 0.0 1.5e-30 106.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE25598.1 - 3.3e-22 78.9 0.0 4.8e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE25598.1 - 7.8e-09 35.7 1.2 8.8e-07 29.0 1.2 2.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE25598.1 - 4.3e-07 29.6 0.0 7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE25598.1 - 2.6e-05 23.4 0.0 7e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EPE25598.1 - 0.00024 20.6 0.0 0.00068 19.1 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EPE25598.1 - 0.0059 16.5 0.0 0.013 15.4 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_7 PF13241.6 EPE25598.1 - 0.037 14.5 0.0 0.065 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Eapp_C PF10238.9 EPE25599.1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.1 1 1 0 2 2 2 0 E2F-associated phosphoprotein DUF4407 PF14362.6 EPE25599.1 - 9.4 5.5 18.5 3.4 6.9 12.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) SKG6 PF08693.10 EPE25600.1 - 0.0022 17.4 0.1 0.0022 17.4 0.1 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 EPE25600.1 - 0.032 14.7 0.4 0.032 14.7 0.4 3.0 2 1 1 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Syndecan PF01034.20 EPE25600.1 - 0.32 11.0 0.6 0.58 10.1 0.6 1.3 1 0 0 1 1 1 0 Syndecan domain Gram_pos_anchor PF00746.21 EPE25600.1 - 0.45 10.5 2.4 1.2 9.2 2.4 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF3664 PF12406.8 EPE25600.1 - 4.1 8.1 9.3 16 6.2 2.8 2.5 1 1 1 2 2 2 0 Surface protein GMC_oxred_C PF05199.13 EPE25602.1 - 1.4e-26 93.7 0.0 2.6e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EPE25602.1 - 1.7e-26 93.3 0.0 2.3e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EPE25603.1 - 6.9e-23 81.4 0.0 8.3e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EPE25603.1 - 0.00011 22.4 0.5 0.00023 21.3 0.5 1.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE25603.1 - 0.00018 20.7 0.0 0.00024 20.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EPE25603.1 - 0.00025 19.9 0.0 0.0003 19.6 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EPE25603.1 - 0.002 17.8 2.1 0.0027 17.3 2.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPE25603.1 - 0.0028 17.0 0.3 0.0041 16.4 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE25603.1 - 0.0038 16.3 0.1 0.0049 16.0 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EPE25603.1 - 0.0046 16.2 0.2 0.0046 16.2 0.2 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE25603.1 - 0.0076 15.5 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family TrkA_N PF02254.18 EPE25603.1 - 0.021 15.1 0.3 0.043 14.1 0.3 1.5 1 0 0 1 1 1 0 TrkA-N domain Peptidase_C25_C PF03785.14 EPE25603.1 - 0.023 14.5 0.2 0.023 14.5 0.2 1.7 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain FAD_binding_3 PF01494.19 EPE25603.1 - 0.096 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pkinase PF00069.25 EPE25604.1 - 2.5e-66 223.8 0.0 3.3e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE25604.1 - 4.5e-29 101.5 0.0 1.9e-28 99.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EPE25604.1 - 0.0038 16.6 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EPE25604.1 - 0.0084 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EPE25604.1 - 0.014 14.8 0.3 0.49 9.7 0.0 2.5 2 1 0 2 2 2 0 Kinase-like FTA2 PF13095.6 EPE25604.1 - 0.031 13.9 0.4 0.95 9.0 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EPE25604.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ANAPC_CDC26 PF10471.9 EPE25605.1 - 0.045 14.6 0.3 0.045 14.6 0.3 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Glyco_transf_28 PF03033.20 EPE25606.1 - 5.9e-20 71.7 0.0 2.4e-19 69.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EPE25606.1 - 4.4e-09 35.7 0.0 1e-08 34.4 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EPE25606.1 - 0.00018 21.5 0.0 0.00076 19.5 0.0 2.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.11 EPE25606.1 - 0.0075 16.6 0.0 0.035 14.5 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain G0-G1_switch_2 PF15103.6 EPE25606.1 - 0.2 12.1 2.6 0.3 11.5 0.2 2.6 3 0 0 3 3 3 0 G0/G1 switch protein 2 adh_short PF00106.25 EPE25607.1 - 6.6e-35 120.3 0.1 8.6e-35 120.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE25607.1 - 7.7e-24 84.5 0.0 9.6e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE25607.1 - 4.6e-06 26.7 0.2 1.6e-05 24.9 0.1 1.8 2 1 0 2 2 2 1 KR domain Agenet PF05641.12 EPE25607.1 - 0.017 15.6 0.0 0.041 14.3 0.0 1.6 1 0 0 1 1 1 0 Agenet domain Methyltransf_25 PF13649.6 EPE25607.1 - 0.033 14.9 0.0 0.072 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 EPE25607.1 - 0.093 12.1 0.1 0.71 9.2 0.0 2.1 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EPE25607.1 - 0.095 12.6 0.1 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EPE25607.1 - 0.13 11.7 0.0 0.82 9.1 0.0 2.1 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.18 EPE25607.1 - 0.14 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Rav1p_C PF12234.8 EPE25608.1 - 5.4e-283 940.2 1.3 6.7e-283 939.9 1.3 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 EPE25608.1 - 0.032 15.1 0.2 1.8 9.6 0.0 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat Sfi1 PF08457.10 EPE25609.1 - 1.6e-72 244.9 93.2 1.1e-39 136.4 29.4 4.1 1 1 2 3 3 3 3 Sfi1 spindle body protein tRNA-synt_1 PF00133.22 EPE25610.1 - 1.1e-220 734.0 0.0 1.5e-220 733.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EPE25610.1 - 1.2e-25 90.3 0.0 1.2e-24 87.0 0.0 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EPE25610.1 - 1.9e-14 53.3 0.1 1.3e-05 24.2 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EPE25610.1 - 0.0011 18.3 0.0 0.097 12.0 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain DUF5315 PF17242.2 EPE25614.1 - 0.036 13.9 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) DUF2600 PF10776.9 EPE25615.1 - 0.003 16.5 0.2 0.0068 15.3 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2600) Glyoxalase_3 PF13468.6 EPE25616.1 - 2.4e-29 102.7 0.0 2.9e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain MIP PF00230.20 EPE25617.1 - 1.2e-05 25.2 0.4 1.4e-05 24.9 0.4 1.2 1 0 0 1 1 1 1 Major intrinsic protein GFA PF04828.14 EPE25618.1 - 0.006 16.9 1.9 0.006 16.9 1.9 2.0 2 1 1 3 3 3 1 Glutathione-dependent formaldehyde-activating enzyme PRMT5_TIM PF17285.2 EPE25619.1 - 6.5e-77 258.2 0.0 8.6e-77 257.8 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 EPE25619.1 - 2.6e-72 242.3 0.0 4.4e-72 241.5 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EPE25619.1 - 5.4e-61 205.5 0.0 9.4e-61 204.8 0.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 EPE25619.1 - 0.2 11.4 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein DUF866 PF05907.13 EPE25620.1 - 4.2e-58 195.7 0.4 2e-56 190.2 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF866) LSM PF01423.22 EPE25620.1 - 2.4e-18 65.6 0.2 3.6e-18 65.0 0.2 1.2 1 0 0 1 1 1 1 LSM domain SH2_2 PF14633.6 EPE25620.1 - 0.012 15.1 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 SH2 domain DUF3828 PF12883.7 EPE25620.1 - 0.069 13.5 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) PPR_2 PF13041.6 EPE25621.1 - 0.0033 17.6 0.0 0.039 14.1 0.0 2.4 2 0 0 2 2 2 1 PPR repeat family LPD11 PF18824.1 EPE25621.1 - 0.14 12.3 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 11 PPR_1 PF12854.7 EPE25621.1 - 0.17 11.6 1.2 0.39 10.5 0.1 2.2 2 0 0 2 2 2 0 PPR repeat adh_short PF00106.25 EPE25622.1 - 2.2e-21 76.2 0.0 2.8e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE25622.1 - 3.2e-19 69.4 0.0 4.2e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE25622.1 - 0.00085 19.3 0.0 0.0012 18.8 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF460 PF04312.13 EPE25622.1 - 0.034 13.9 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Ribosomal_L26 PF16906.5 EPE25623.1 - 5.4e-38 129.3 3.3 7.2e-38 128.9 3.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EPE25623.1 - 1e-08 34.8 0.9 2.3e-08 33.7 0.9 1.6 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.11 EPE25623.1 - 0.12 12.4 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) GHL5 PF14872.6 EPE25623.1 - 0.14 10.1 0.0 0.16 10.0 0.0 1.0 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 Sugar_tr PF00083.24 EPE25624.1 - 4.1e-139 464.3 19.1 4.7e-139 464.1 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE25624.1 - 8e-24 84.2 40.2 2.5e-19 69.4 16.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPE25624.1 - 0.00011 20.9 19.3 0.0018 16.9 7.1 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein UNC45-central PF11701.8 EPE25625.1 - 6.7e-54 182.0 1.4 3.2e-51 173.3 0.0 4.3 5 1 0 5 5 5 1 Myosin-binding striated muscle assembly central Arm PF00514.23 EPE25625.1 - 0.00011 22.1 7.9 4.3 7.5 0.0 7.1 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EPE25625.1 - 0.0068 16.4 0.3 5.9 7.0 0.0 3.8 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 EPE25625.1 - 0.11 12.8 9.1 1.9 9.0 0.4 5.5 5 2 3 8 8 8 0 HEAT repeats Cnd3 PF12719.7 EPE25625.1 - 1.3 8.1 4.3 43 3.2 0.2 3.4 2 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Tfb4 PF03850.14 EPE25626.1 - 7.5e-108 360.2 0.8 8.7e-108 360.0 0.8 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Asparaginase_2 PF01112.18 EPE25627.1 - 4.3e-42 144.2 3.7 1e-26 93.7 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Actin PF00022.19 EPE25628.1 - 3.7e-87 292.6 0.0 1.5e-84 284.0 0.0 2.0 1 1 0 1 1 1 1 Actin ADH_N PF08240.12 EPE25629.1 - 2.2e-28 98.3 2.0 2.3e-28 98.2 0.6 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE25629.1 - 2.7e-25 88.9 0.1 4.1e-25 88.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE25629.1 - 5.4e-05 24.3 0.0 8.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPE25629.1 - 0.022 14.1 0.5 0.034 13.5 0.5 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EPE25629.1 - 0.026 14.0 0.1 0.046 13.2 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 EPE25629.1 - 0.059 12.7 0.2 0.1 11.9 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EPE25629.1 - 0.14 11.6 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 EPE25630.1 - 9.8e-75 251.3 0.0 1.4e-74 250.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE25630.1 - 8.2e-31 107.2 0.0 2.5e-22 79.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EPE25630.1 - 1.8e-06 27.5 0.1 0.5 9.6 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 EPE25630.1 - 0.016 14.0 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EPE25630.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPE25630.1 - 0.053 13.4 0.0 0.71 9.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family McyA_C PF12593.8 EPE25632.1 - 0.11 12.3 0.1 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 Microcystin synthetase C terminal OB_NTP_bind PF07717.16 EPE25633.1 - 2.7e-23 82.1 0.0 7.2e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EPE25633.1 - 1.9e-18 66.7 0.1 4.5e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EPE25633.1 - 4.9e-11 43.0 0.0 2.2e-10 40.9 0.0 2.1 3 0 0 3 3 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPE25633.1 - 1.9e-06 27.7 0.1 4.1e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EPE25633.1 - 4e-06 27.1 0.2 1.4e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EPE25633.1 - 0.0017 18.0 0.0 0.0083 15.8 0.0 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EPE25633.1 - 0.033 13.9 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EPE25633.1 - 0.039 13.2 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 EPE25633.1 - 0.048 13.6 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain PhoH PF02562.16 EPE25633.1 - 0.081 12.4 0.1 0.28 10.6 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein T2SSE PF00437.20 EPE25633.1 - 0.089 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 EPE25633.1 - 0.1 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain TFIID_30kDa PF03540.13 EPE25634.1 - 4.9e-24 84.0 0.2 8e-24 83.3 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 EPE25634.1 - 0.12 12.9 0.6 0.28 11.7 0.6 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_S19 PF00203.21 EPE25635.1 - 2.7e-28 97.6 0.0 3.2e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Mre11_DNA_bind PF04152.14 EPE25636.1 - 4.9e-51 173.4 0.2 9.4e-51 172.5 0.2 1.5 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EPE25636.1 - 1.8e-16 61.2 1.6 3.5e-16 60.3 1.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPE25636.1 - 3.8e-05 23.9 0.0 0.0003 21.0 0.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Med3 PF11593.8 EPE25636.1 - 2.5 7.2 5.5 3.9 6.6 5.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HD PF01966.22 EPE25637.1 - 3.6e-05 24.0 0.1 8.1e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 HD domain adh_short PF00106.25 EPE25638.1 - 6.4e-24 84.5 0.2 1e-22 80.6 0.2 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE25638.1 - 6.7e-15 55.3 0.0 5e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE25638.1 - 5.4e-06 26.4 0.0 7.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Kinesin PF00225.23 EPE25639.1 - 2.5e-90 302.8 3.2 5.1e-90 301.8 0.0 3.0 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EPE25639.1 - 1e-19 71.0 0.0 9.5e-15 54.8 0.0 3.5 2 1 1 3 3 3 2 Microtubule binding bZIP_1 PF00170.21 EPE25639.1 - 0.029 14.5 0.2 0.029 14.5 0.2 9.9 12 0 0 12 12 12 0 bZIP transcription factor HisKA PF00512.25 EPE25639.1 - 8.4 6.5 11.4 4.1 7.5 1.9 4.5 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain Tri3 PF07428.11 EPE25640.1 - 8.6e-30 104.0 0.0 1.5e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 ORC6 PF05460.13 EPE25641.1 - 3.6e-34 118.6 8.9 1.2e-33 116.9 2.2 2.0 2 0 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) EF-hand_6 PF13405.6 EPE25642.1 - 8.2e-06 25.4 5.8 0.001 18.8 0.6 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EPE25642.1 - 0.00031 21.1 1.7 0.00071 20.0 1.7 1.6 1 0 0 1 1 1 1 EF-hand domain pair SUKH_6 PF14568.6 EPE25642.1 - 0.048 14.1 0.6 1 9.8 0.7 2.4 2 1 0 2 2 2 0 SMI1-KNR4 cell-wall Met_10 PF02475.16 EPE25643.1 - 2.8e-05 24.0 0.1 0.00014 21.6 0.0 2.1 2 1 0 2 2 2 1 Met-10+ like-protein HLH PF00010.26 EPE25644.1 - 3.9e-10 39.5 1.3 3.9e-10 39.5 1.3 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DENN PF02141.21 EPE25645.1 - 1.5e-40 139.1 0.1 2.6e-40 138.4 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EPE25645.1 - 4.5e-06 27.3 0.0 1.9e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 uDENN domain LPP PF04728.13 EPE25645.1 - 0.089 13.2 1.4 0.29 11.6 0.7 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF724 PF05266.14 EPE25645.1 - 0.32 10.8 9.9 0.87 9.4 9.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Cnn_1N PF07989.11 EPE25645.1 - 2.3 8.4 13.6 0.097 12.8 2.1 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 zf-HIT PF04438.16 EPE25646.1 - 1.8e-09 37.3 10.5 3.1e-09 36.5 10.5 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF829 PF05705.14 EPE25647.1 - 2.1e-30 106.4 0.3 3.1e-30 105.9 0.3 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) His_Phos_2 PF00328.22 EPE25648.1 - 1.3e-05 24.8 0.0 3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CSN7a_helixI PF18392.1 EPE25648.1 - 0.2 11.6 1.0 0.41 10.6 1.0 1.4 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Aldedh PF00171.22 EPE25650.1 - 2.6e-187 623.0 0.7 2.9e-187 622.8 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TRF PF08558.10 EPE25651.1 - 8.4e-62 208.9 0.3 1.3e-61 208.3 0.3 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 EPE25651.1 - 0.00032 20.8 0.0 0.00057 20.0 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain FAD_binding_3 PF01494.19 EPE25652.1 - 2.5e-08 33.6 0.0 1.2e-07 31.3 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPE25652.1 - 0.022 14.4 0.0 0.079 12.5 0.0 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 EPE25652.1 - 0.047 12.9 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 EPE25652.1 - 0.091 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Abhydrolase_3 PF07859.13 EPE25653.1 - 5.4e-64 215.9 0.0 9.6e-64 215.1 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 EPE25653.1 - 4.8e-09 35.6 0.1 1.2e-08 34.4 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EPE25653.1 - 3e-06 26.9 0.0 1.2e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 EPE25653.1 - 8.1e-05 21.7 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Thioesterase PF00975.20 EPE25653.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain Pkinase PF00069.25 EPE25654.1 - 8.8e-10 38.4 0.0 9.1e-09 35.1 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE25654.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.5 2 0 0 2 2 2 0 Protein tyrosine kinase Putative_PNPOx PF01243.20 EPE25655.1 - 3.9e-13 49.4 0.0 4.2e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 EPE25655.1 - 3.3e-06 27.4 0.0 0.00059 20.1 0.0 3.1 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain FAD_binding_9 PF08021.11 EPE25655.1 - 0.048 13.9 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain adh_short PF00106.25 EPE25656.1 - 2.2e-41 141.5 0.0 3.2e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE25656.1 - 6.1e-28 98.0 0.0 8.3e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE25656.1 - 1.7e-09 37.8 0.0 2.4e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EPE25656.1 - 0.00065 19.2 0.0 0.00095 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EPE25656.1 - 0.0019 17.7 0.0 0.0046 16.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EPE25656.1 - 0.028 13.5 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Asparaginase_2 PF01112.18 EPE25657.1 - 4.6e-53 180.2 0.1 1.6e-25 89.8 0.1 3.4 3 0 0 3 3 3 3 Asparaginase DUF2380 PF09533.10 EPE25657.1 - 0.071 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) PTPRCAP PF15713.5 EPE25658.1 - 0.0081 16.5 3.3 0.011 16.0 3.3 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated STIL_N PF15253.6 EPE25658.1 - 0.98 8.3 2.5 1.1 8.1 2.5 1.1 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus Presenilin PF01080.17 EPE25658.1 - 3.9 6.1 6.1 4.7 5.9 6.1 1.0 1 0 0 1 1 1 0 Presenilin SNF2_N PF00176.23 EPE25659.1 - 1.3e-63 214.9 0.1 1e-62 211.9 0.1 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC PF07967.13 EPE25659.1 - 4.1e-41 140.1 9.9 6.3e-36 123.4 0.7 3.5 3 0 0 3 3 3 2 C3HC zinc finger-like Rsm1 PF08600.10 EPE25659.1 - 1.9e-23 82.4 0.1 1.9e-23 82.4 0.1 2.4 2 0 0 2 2 2 1 Rsm1-like Helicase_C PF00271.31 EPE25659.1 - 2.3e-16 60.1 0.0 7.7e-16 58.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE25659.1 - 5.6e-07 29.7 0.0 1.6e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit BIR PF00653.21 EPE25659.1 - 0.085 13.5 7.1 0.53 11.0 0.2 3.7 3 1 0 3 3 3 0 Inhibitor of Apoptosis domain CTU2 PF10288.9 EPE25659.1 - 1.6 9.0 8.3 8.8 6.6 2.5 3.5 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Inositol_P PF00459.25 EPE25660.1 - 1.3e-50 172.4 3.3 4.3e-50 170.7 3.3 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.23 EPE25661.1 - 4e-23 81.9 0.3 2.2e-10 41.1 0.0 3.0 2 1 0 2 2 2 2 Ribosomal protein L6 HET PF06985.11 EPE25662.1 - 1.4e-13 51.4 6.6 1.5e-12 48.1 6.6 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ICL PF00463.21 EPE25664.1 - 3.2e-195 649.6 0.1 3.8e-195 649.4 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EPE25664.1 - 9.8e-11 41.6 0.1 2e-09 37.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Citrate_synt PF00285.21 EPE25665.1 - 2.4e-102 342.7 0.0 2.8e-102 342.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain WSC PF01822.19 EPE25666.1 - 1.3e-46 156.7 33.8 1e-17 64.1 6.0 3.7 3 0 0 3 3 3 3 WSC domain PQQ_3 PF13570.6 EPE25666.1 - 0.00056 20.3 8.4 0.26 11.9 0.0 5.2 5 0 0 5 5 5 2 PQQ-like domain SnoaL_2 PF12680.7 EPE25667.1 - 0.00013 22.5 0.1 0.00021 21.9 0.1 1.4 1 1 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.16 EPE25668.1 - 8.8e-37 126.8 26.4 8.8e-37 126.8 26.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE25668.1 - 4.6e-11 42.2 9.0 4.6e-11 42.2 9.0 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EPE25668.1 - 4.7e-06 25.3 5.9 9.5e-06 24.3 5.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4407 PF14362.6 EPE25668.1 - 1.6 8.0 3.3 3.4 6.9 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADH_N PF08240.12 EPE25669.1 - 3.1e-06 27.0 0.0 5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Tautomerase_3 PF14832.6 EPE25671.1 - 2.1e-10 41.0 0.0 4.4e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme WVELL PF14043.6 EPE25671.1 - 0.14 12.0 0.3 0.29 11.0 0.3 1.5 1 0 0 1 1 1 0 WVELL protein Peptidase_M19 PF01244.21 EPE25672.1 - 3e-98 328.9 0.0 3.5e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Imm70 PF15601.6 EPE25672.1 - 0.08 12.5 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 70 p450 PF00067.22 EPE25673.1 - 2.9e-20 72.5 0.0 3.6e-19 68.9 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 DFRP_C PF16543.5 EPE25675.1 - 4.7e-26 91.1 5.7 4.7e-26 91.1 5.7 3.6 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 EPE25675.1 - 3.3e-05 23.7 3.6 3.3e-05 23.7 3.6 2.4 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EPE25675.1 - 0.00029 21.5 18.4 0.00046 20.9 5.6 3.8 2 1 1 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 EPE25675.1 - 0.00052 19.8 10.8 0.0025 17.6 4.3 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EPE25675.1 - 0.011 15.9 1.8 0.31 11.3 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger containing family zf_CCCH_4 PF18345.1 EPE25675.1 - 0.015 15.3 9.8 0.015 15.3 9.8 3.2 4 0 0 4 4 4 0 Zinc finger domain zf-CCCH_2 PF14608.6 EPE25675.1 - 0.45 11.1 13.8 1.5 9.4 5.1 3.0 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger FYDLN_acid PF09538.10 EPE25675.1 - 8.4 7.1 25.9 1.8 9.3 6.8 3.6 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Ost4 PF10215.9 EPE25676.1 - 4.9e-18 64.6 0.6 6e-18 64.4 0.6 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase RRM_1 PF00076.22 EPE25677.1 - 3.8e-13 49.0 0.0 6.8e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EPE25677.1 - 1.8e-05 25.2 1.9 1.8e-05 25.2 1.9 3.0 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 Cutinase PF01083.22 EPE25678.1 - 2.3e-47 161.2 0.4 2.9e-47 160.9 0.4 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 EPE25678.1 - 0.0094 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_1 PF00561.20 EPE25678.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold AAA PF00004.29 EPE25679.1 - 2e-18 67.1 0.1 5.9e-18 65.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE25679.1 - 0.0012 19.3 0.4 0.0041 17.5 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPE25679.1 - 0.0017 18.6 0.4 0.031 14.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 EPE25679.1 - 0.022 15.2 0.0 0.059 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EPE25679.1 - 0.032 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EPE25679.1 - 0.034 14.1 0.0 0.078 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EPE25679.1 - 0.074 13.2 0.0 0.37 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EPE25679.1 - 0.14 12.7 0.0 0.49 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EPE25679.1 - 0.16 11.7 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EPE25679.1 - 0.19 11.1 0.8 0.56 9.5 0.3 1.9 1 1 1 2 2 2 0 KaiC SNF2_N PF00176.23 EPE25681.1 - 1.5e-27 96.3 0.3 5.9e-24 84.4 0.1 3.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE25681.1 - 1.3e-11 44.8 0.0 4.5e-11 43.1 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EPE25681.1 - 0.00015 21.7 9.2 0.00028 20.8 9.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EPE25681.1 - 0.0032 17.7 9.4 0.0032 17.7 9.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EPE25681.1 - 0.0084 16.0 10.1 0.019 14.8 10.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE25681.1 - 0.04 13.8 8.7 0.11 12.4 8.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EPE25681.1 - 0.072 13.1 8.5 0.22 11.6 8.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger DUF5447 PF17525.2 EPE25681.1 - 0.14 12.6 3.1 0.41 11.1 3.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5447) FYVE PF01363.21 EPE25681.1 - 0.24 11.6 4.9 0.62 10.2 4.9 1.7 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4_2 PF13923.6 EPE25681.1 - 0.38 10.6 12.1 0.018 14.9 6.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 EPE25681.1 - 1 9.5 4.6 0.81 9.9 2.0 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_11 PF17123.5 EPE25681.1 - 1 9.1 8.6 2.4 8.0 8.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger Snf7 PF03357.21 EPE25682.1 - 5.5e-25 88.0 8.3 5.5e-25 88.0 8.3 1.7 1 1 1 2 2 2 1 Snf7 MerR-DNA-bind PF09278.11 EPE25682.1 - 3.7 8.2 9.8 18 6.0 0.4 3.7 4 0 0 4 4 4 0 MerR, DNA binding PIH1_CS PF18201.1 EPE25683.1 - 6.2e-06 26.5 0.3 2.5e-05 24.6 0.2 1.8 1 1 1 2 2 2 1 PIH1 CS-like domain CS PF04969.16 EPE25683.1 - 0.00017 22.5 0.2 0.00029 21.8 0.2 1.3 1 0 0 1 1 1 1 CS domain RabGAP-TBC PF00566.18 EPE25684.1 - 1e-48 165.9 0.1 1.6e-48 165.2 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CALM_bind PF16025.5 EPE25684.1 - 1.9 9.0 9.3 0.075 13.5 2.6 2.3 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding adh_short_C2 PF13561.6 EPE25685.1 - 3.7e-57 193.6 4.0 4.4e-57 193.3 4.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE25685.1 - 3.2e-44 150.7 3.1 3.9e-44 150.4 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE25685.1 - 6.2e-09 36.0 1.0 1.4e-08 34.8 1.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE25685.1 - 0.0052 16.3 0.4 0.0067 15.9 0.4 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 EPE25685.1 - 0.025 15.3 0.1 0.14 12.9 0.1 2.1 1 1 0 2 2 2 0 Methyltransferase domain Period_C PF12114.8 EPE25687.1 - 0.47 10.0 5.8 0.59 9.7 5.8 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Gly-zipper_Omp PF13488.6 EPE25689.1 - 0.0008 19.4 5.2 0.013 15.5 0.3 2.3 2 0 0 2 2 2 2 Glycine zipper Gly-zipper_YMGG PF13441.6 EPE25689.1 - 0.029 14.1 8.8 0.056 13.2 8.8 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 EPE25689.1 - 1.4 8.8 16.9 0.97 9.3 4.6 2.1 1 1 1 2 2 2 0 Glycine zipper 2TM domain TLE_N PF03920.15 EPE25690.1 - 0.0026 17.9 0.9 0.0054 16.8 0.9 1.6 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain Fungal_TACC PF12709.7 EPE25690.1 - 0.036 14.5 0.5 0.12 12.9 0.5 1.8 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins Tho2 PF11262.8 EPE25690.1 - 0.24 10.6 4.5 0.41 9.8 4.5 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Jnk-SapK_ap_N PF09744.9 EPE25690.1 - 0.5 10.6 11.4 1 9.5 11.4 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Mitofilin PF09731.9 EPE25691.1 - 0.76 8.5 24.8 0.058 12.2 20.2 1.4 2 0 0 2 2 2 0 Mitochondrial inner membrane protein GREB1 PF15782.5 EPE25691.1 - 1.3 6.1 12.1 1.6 5.7 12.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer tRNA_int_end_N2 PF12928.7 EPE25692.1 - 5.8e-26 90.5 0.1 9.4e-26 89.8 0.1 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EPE25692.1 - 0.066 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain Arrestin_C PF02752.22 EPE25693.1 - 1.4e-11 45.0 0.2 7.3e-11 42.7 0.0 2.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Pro_isomerase PF00160.21 EPE25694.1 - 7.5e-50 169.3 0.1 8.5e-50 169.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PAP2 PF01569.21 EPE25695.1 - 1.4e-19 70.2 1.6 1.4e-19 70.2 1.6 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EPE25695.1 - 0.0016 18.1 9.8 0.026 14.2 9.2 3.1 2 1 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EPE25695.1 - 1.2 9.3 3.9 0.82 9.8 0.3 2.3 2 0 0 2 2 2 0 Divergent PAP2 family Ras PF00071.22 EPE25696.1 - 2.7e-48 163.6 0.0 3.6e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE25696.1 - 3.6e-20 72.4 0.0 7.1e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE25696.1 - 5e-05 22.8 0.0 8.6e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 EPE25696.1 - 0.054 13.0 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 EPE25696.1 - 0.16 11.3 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DASH_Dad1 PF08649.10 EPE25697.1 - 6.7e-26 90.2 2.8 8.6e-26 89.9 2.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 EPE25697.1 - 0.071 13.1 0.1 0.095 12.7 0.1 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 PTR2 PF00854.21 EPE25698.1 - 1.7e-39 135.8 1.3 1.1e-21 77.1 0.1 2.1 1 1 1 2 2 2 2 POT family COPI_assoc PF08507.10 EPE25698.1 - 2.4 8.2 7.8 8.3 6.5 0.8 2.8 2 0 0 2 2 2 0 COPI associated protein TMF_DNA_bd PF12329.8 EPE25700.1 - 2e-06 27.7 5.8 2e-06 27.7 5.8 2.3 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding SYCE1 PF15233.6 EPE25700.1 - 0.0051 16.9 6.3 0.01 15.9 6.3 1.4 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 Spc7 PF08317.11 EPE25700.1 - 0.011 14.6 8.6 0.02 13.8 8.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4200 PF13863.6 EPE25700.1 - 0.02 15.3 6.8 0.02 15.3 6.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) PKcGMP_CC PF16808.5 EPE25700.1 - 0.049 13.5 2.7 0.16 11.8 2.7 1.9 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4404 PF14357.6 EPE25700.1 - 0.49 11.1 2.7 0.86 10.3 0.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) TMPIT PF07851.13 EPE25700.1 - 1.5 8.0 3.6 2.5 7.3 3.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein GDPD PF03009.17 EPE25701.1 - 5e-73 246.0 0.0 1.3e-72 244.7 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EPE25701.1 - 8.5e-27 93.6 0.3 2.3e-09 37.7 0.1 4.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE25701.1 - 5.3e-23 81.1 2.3 2.6e-08 34.3 0.1 5.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE25701.1 - 4.3e-22 77.9 0.1 1e-07 32.0 0.0 4.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) SPX PF03105.19 EPE25701.1 - 1e-19 71.8 5.6 6.5e-11 42.8 0.0 4.1 2 1 2 4 4 4 2 SPX domain Ank PF00023.30 EPE25701.1 - 5.3e-15 55.1 8.4 0.00029 21.2 0.0 6.7 5 1 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EPE25701.1 - 1.2e-13 49.8 5.0 0.0047 17.3 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeat DBR1 PF05011.13 EPE25702.1 - 5.1e-46 156.5 0.0 2.3e-45 154.4 0.0 1.9 1 1 1 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EPE25702.1 - 1.3e-05 25.8 0.6 2e-05 25.2 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rpr2 PF04032.16 EPE25703.1 - 1.6e-12 47.5 4.1 1.6e-12 47.5 4.1 1.7 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Basic PF01586.16 EPE25703.1 - 0.01 17.0 2.8 0.01 17.0 2.8 1.7 2 0 0 2 2 2 0 Myogenic Basic domain Hepcidin PF06446.12 EPE25703.1 - 0.071 13.5 2.4 0.071 13.5 2.4 2.4 2 0 0 2 2 2 0 Hepcidin N-SET PF11764.8 EPE25703.1 - 0.11 12.7 1.0 0.13 12.4 0.7 1.3 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N zf-ZPR1 PF03367.13 EPE25704.1 - 8.9e-113 373.4 0.0 3.7e-58 195.9 0.0 2.6 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-RRPl_C4 PF17026.5 EPE25704.1 - 0.2 11.8 2.8 0.79 9.9 0.3 2.3 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-C2H2 PF00096.26 EPE25707.1 - 3.5e-12 46.0 9.4 5.9e-06 26.5 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE25707.1 - 7.9e-09 35.6 7.7 0.00053 20.6 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPE25707.1 - 9.4e-09 35.3 9.3 3.8e-05 23.9 1.7 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 EPE25707.1 - 0.0076 16.6 7.2 0.49 10.9 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EPE25707.1 - 0.019 15.3 11.3 0.019 15.2 0.0 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 EPE25707.1 - 0.075 12.8 3.6 0.12 12.1 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 EPE25707.1 - 0.21 11.6 3.8 9.6 6.3 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger C5HCH PF17982.1 EPE25707.1 - 0.31 11.2 4.2 1.4 9.1 3.6 2.2 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-C2HE PF16278.5 EPE25707.1 - 1.4 9.4 6.4 18 5.9 1.1 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 EPE25707.1 - 7.4 6.7 7.5 11 6.1 3.0 2.9 2 1 0 2 2 2 0 BED zinc finger Pkinase PF00069.25 EPE25708.1 - 8e-70 235.2 0.0 3.4e-69 233.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 EPE25708.1 - 2.4e-43 146.6 0.5 5.2e-43 145.5 0.5 1.6 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 EPE25708.1 - 1.9e-34 119.1 0.0 8.2e-33 113.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE25708.1 - 0.00014 21.3 0.0 0.00033 20.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EPE25708.1 - 0.00044 19.3 0.1 0.003 16.6 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EPE25708.1 - 0.0035 16.7 0.0 0.0085 15.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EPE25708.1 - 0.029 13.9 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EPE25708.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EPE25708.1 - 0.04 13.5 0.1 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 RIO1 family SMC_N PF02463.19 EPE25709.1 - 8.9e-24 84.1 0.0 1.5e-23 83.4 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EPE25709.1 - 3.4e-18 66.9 2.1 3.4e-18 66.9 2.1 5.4 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 EPE25709.1 - 1.3e-09 38.2 15.1 3.8e-09 36.7 0.2 3.1 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EPE25709.1 - 2.9e-08 33.9 1.1 0.0049 16.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EPE25709.1 - 0.0018 18.0 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Med9 PF07544.13 EPE25709.1 - 0.012 15.7 4.7 0.012 15.7 4.7 7.1 5 2 1 6 6 6 0 RNA polymerase II transcription mediator complex subunit 9 AAA PF00004.29 EPE25709.1 - 0.057 13.8 1.0 0.32 11.4 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EPE25709.1 - 0.69 10.4 0.0 0.69 10.4 0.0 5.4 3 2 0 4 4 4 0 ABC transporter NPV_P10 PF05531.12 EPE25709.1 - 0.92 10.0 23.7 2.6 8.6 1.0 6.9 5 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Hemagglutinin PF00509.18 EPE25709.1 - 0.93 7.8 3.6 16 3.7 0.0 2.7 2 0 0 2 2 2 0 Haemagglutinin Ctr PF04145.15 EPE25712.1 - 1.3e-28 100.5 0.8 1.5e-28 100.3 0.8 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF4134 PF13572.6 EPE25712.1 - 0.07 13.4 0.6 0.15 12.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) Ferric_reduct PF01794.19 EPE25713.1 - 5.8e-20 71.7 8.8 1.5e-19 70.4 7.0 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EPE25713.1 - 1.5e-17 63.6 0.0 3.6e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EPE25713.1 - 1.1e-15 58.0 0.0 1.9e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Lyase_1 PF00206.20 EPE25714.1 - 7.5e-110 367.2 0.0 1.2e-109 366.5 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EPE25714.1 - 7.4e-21 74.3 0.0 1.9e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Malate_synthase PF01274.22 EPE25715.1 - 1e-228 759.9 0.0 1.1e-228 759.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase YjcB PF15940.5 EPE25717.1 - 0.068 13.3 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function FAD_binding_3 PF01494.19 EPE25718.1 - 5.2e-26 91.7 0.0 1.2e-25 90.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE25718.1 - 1.6e-05 24.3 0.0 0.0059 15.9 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EPE25718.1 - 2.8e-05 23.3 0.0 0.00037 19.7 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 EPE25718.1 - 4.5e-05 23.2 0.0 0.072 12.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EPE25718.1 - 0.00046 19.4 0.0 0.0023 17.0 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPE25718.1 - 0.016 15.4 0.0 0.046 14.0 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EPE25718.1 - 0.044 13.8 0.1 0.23 11.5 0.0 2.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EPE25718.1 - 0.057 12.7 0.5 0.2 10.9 0.3 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EPE25718.1 - 0.061 12.2 0.5 2.4 6.9 0.1 2.6 2 1 1 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.14 EPE25718.1 - 0.13 10.9 0.0 0.54 8.9 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EPE25718.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DUF2428 PF10350.9 EPE25720.1 - 0.089 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Phage_TTP_11 PF16460.5 EPE25721.1 - 0.057 13.3 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube, TTP, lambda-like DUF4191 PF13829.6 EPE25721.1 - 0.96 8.7 0.0 0.96 8.7 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) SRF-TF PF00319.18 EPE25722.1 - 5e-07 29.1 0.1 7.6e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Mg_trans_NIPA PF05653.14 EPE25723.1 - 1.9e-13 50.2 7.5 3.3e-13 49.4 7.5 1.3 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EPE25723.1 - 2.4e-05 24.5 17.9 0.0014 18.8 0.0 3.3 2 1 1 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 EPE25723.1 - 0.0004 19.7 0.8 0.0004 19.7 0.8 2.5 1 1 1 2 2 2 1 Purine nucleobase transmembrane transport vATP-synt_E PF01991.18 EPE25724.1 - 1.1e-65 220.8 10.0 1.3e-65 220.6 10.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Phe_tRNA-synt_N PF02912.18 EPE25724.1 - 0.097 12.6 0.2 0.097 12.6 0.2 3.7 4 1 0 4 4 4 0 Aminoacyl tRNA synthetase class II, N-terminal domain Methyltransf_7 PF03492.15 EPE25724.1 - 0.16 11.2 2.9 0.24 10.6 2.9 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase FAM178 PF14816.6 EPE25725.1 - 0.0025 16.8 1.3 0.02 13.9 0.5 2.4 1 1 1 2 2 2 1 Family of unknown function, FAM178 PhoLip_ATPase_C PF16212.5 EPE25726.1 - 1.1e-80 271.1 26.8 1.1e-80 271.1 26.8 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EPE25726.1 - 1.6e-19 69.4 1.0 4.6e-19 67.9 1.0 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EPE25726.1 - 1.8e-12 47.2 0.0 8.3e-12 45.0 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EPE25726.1 - 5.5e-12 46.4 0.8 1.1e-07 32.4 0.2 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EPE25726.1 - 4.2e-05 23.1 0.0 4.2e-05 23.1 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EPE25726.1 - 0.0085 15.9 2.0 0.012 15.3 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SEN1_N PF12726.7 EPE25727.1 - 3.3e-199 663.8 3.5 3.3e-199 663.8 3.5 1.5 2 0 0 2 2 2 1 SEN1 N terminal AAA_11 PF13086.6 EPE25727.1 - 5.1e-70 236.2 1.0 5.1e-70 236.2 1.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EPE25727.1 - 3.6e-62 209.5 0.0 7.4e-62 208.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPE25727.1 - 2.4e-08 33.9 0.0 7.9e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EPE25727.1 - 2.3e-07 31.2 0.0 1.2e-06 29.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EPE25727.1 - 6.5e-07 29.3 0.1 0.006 16.4 0.1 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 EPE25727.1 - 3e-06 27.0 0.5 0.026 14.0 0.0 3.1 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_23 PF13476.6 EPE25727.1 - 0.038 14.5 4.8 0.074 13.5 1.8 2.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EPE25727.1 - 0.043 14.1 0.0 0.23 11.7 0.0 2.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EPE25727.1 - 0.089 12.6 0.5 0.52 10.0 0.0 2.5 3 0 0 3 3 3 0 DEAD/DEAH box helicase ResIII PF04851.15 EPE25727.1 - 0.12 12.3 0.2 0.48 10.4 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 EPE25727.1 - 0.13 12.1 0.1 0.38 10.5 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain rve_3 PF13683.6 EPE25727.1 - 0.17 11.7 0.2 9.5 6.1 0.0 2.8 2 0 0 2 2 2 0 Integrase core domain Cwf_Cwc_15 PF04889.12 EPE25727.1 - 9 5.9 18.6 1 9.0 3.2 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein KIAA1430 PF13879.6 EPE25728.1 - 0.2 12.4 0.2 0.2 12.4 0.2 3.2 3 0 0 3 3 3 0 KIAA1430 homologue Pectate_lyase PF03211.13 EPE25729.1 - 1.1e-77 260.2 10.2 1.3e-77 259.9 10.2 1.0 1 0 0 1 1 1 1 Pectate lyase Phosphoesterase PF04185.14 EPE25730.1 - 3.1e-37 128.6 1.8 2.9e-35 122.1 1.0 2.9 1 1 1 2 2 2 1 Phosphoesterase family PI3K_rbd PF00794.18 EPE25730.1 - 0.017 15.3 0.0 0.075 13.2 0.0 2.0 2 0 0 2 2 2 0 PI3-kinase family, ras-binding domain SLATT_fungal PF18142.1 EPE25731.1 - 1.4e-24 86.3 0.2 2e-24 85.9 0.2 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain 5_nucleotid_C PF02872.18 EPE25732.1 - 0.012 15.8 0.0 0.06 13.6 0.0 2.0 1 1 1 2 2 2 0 5'-nucleotidase, C-terminal domain DUF743 PF05332.11 EPE25732.1 - 0.028 14.5 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF743) PHO4 PF01384.20 EPE25733.1 - 4.2e-120 400.8 15.2 4.9e-120 400.6 15.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family Amnionless PF14828.6 EPE25733.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 Amnionless Fungal_trans PF04082.18 EPE25734.1 - 9.3e-32 110.1 0.3 1.6e-31 109.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 EPE25734.1 - 1.6e-09 37.5 3.4 2.6e-08 33.5 3.4 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EPE25734.1 - 0.00045 20.7 0.6 0.0011 19.4 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE25734.1 - 0.00057 19.1 0.9 0.0013 17.9 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE25734.1 - 0.0021 17.4 0.2 0.0069 15.7 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE25734.1 - 0.0072 15.1 0.4 0.017 13.9 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EPE25734.1 - 0.018 14.3 0.1 0.065 12.5 0.0 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EPE25734.1 - 0.043 13.1 0.1 0.17 11.1 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EPE25734.1 - 0.052 12.9 0.2 0.089 12.1 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EPE25734.1 - 0.15 11.3 0.2 6.2 6.0 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DAO PF01266.24 EPE25734.1 - 0.29 10.7 3.8 2.4 7.7 1.4 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase DUF5401 PF17380.2 EPE25734.1 - 1.1 7.3 2.4 1.6 6.7 2.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) zf-C2H2 PF00096.26 EPE25735.1 - 0.0077 16.6 0.5 0.0077 16.6 0.5 5.1 4 1 1 5 5 5 2 Zinc finger, C2H2 type Megourin PF17560.2 EPE25735.1 - 0.12 12.6 0.7 0.32 11.3 0.7 1.7 1 0 0 1 1 1 0 Aphid Megourins zf-BED PF02892.15 EPE25735.1 - 4.3 7.4 10.3 4 7.5 0.2 3.2 3 0 0 3 3 3 0 BED zinc finger Oxidored_FMN PF00724.20 EPE25737.1 - 2.7e-57 194.6 0.0 3.3e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1611_N PF17396.2 EPE25737.1 - 0.0053 17.0 0.0 0.56 10.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1611_N) Rossmann-like domain NTP_transferase PF00483.23 EPE25738.1 - 2.1e-30 106.1 0.0 2.7e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EPE25738.1 - 2e-10 40.0 5.6 9.4e-07 28.3 0.0 3.6 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EPE25738.1 - 8.4e-08 32.7 0.0 1.3e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EPE25738.1 - 0.014 15.1 1.3 2.4 8.0 0.0 4.2 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 EPE25738.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Dynamin_N PF00350.23 EPE25739.1 - 1.6e-21 77.1 0.0 4.8e-21 75.5 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EPE25739.1 - 3.9e-14 52.6 0.2 7.2e-10 38.6 0.0 2.6 2 1 0 2 2 2 2 Dynamin central region GED PF02212.18 EPE25739.1 - 2e-05 24.7 0.2 6.5e-05 23.0 0.2 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EPE25739.1 - 0.00056 20.0 0.0 0.013 15.6 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EPE25739.1 - 0.0014 19.1 0.0 0.0062 17.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EPE25739.1 - 0.03 14.2 0.1 0.061 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 EPE25739.1 - 0.059 13.6 0.3 0.65 10.2 0.0 2.7 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase WbqC PF08889.11 EPE25739.1 - 0.077 12.9 0.7 7.3 6.4 0.2 2.4 2 0 0 2 2 2 0 WbqC-like protein family AAA_29 PF13555.6 EPE25739.1 - 0.1 12.3 0.3 0.24 11.1 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EPE25739.1 - 0.14 11.8 0.8 0.63 9.7 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain MFS_1 PF07690.16 EPE25740.1 - 1.1e-19 70.5 22.4 2.6e-17 62.8 1.8 3.3 3 1 0 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 EPE25740.1 - 7.9e-06 25.4 0.1 7.9e-06 25.4 0.1 3.5 3 1 1 4 4 4 1 Uncharacterised MFS-type transporter YbfB TraQ PF09679.10 EPE25740.1 - 0.0024 17.7 0.1 0.01 15.7 0.1 2.1 1 0 0 1 1 1 1 Type-F conjugative transfer system pilin chaperone (TraQ) DUF4064 PF13273.6 EPE25740.1 - 7.6 6.9 7.3 4.6 7.6 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) FAD_binding_7 PF03441.14 EPE25741.1 - 2.3e-46 157.9 0.1 3.7e-46 157.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EPE25741.1 - 1.1e-21 77.5 0.0 2e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Coatomer_E PF04733.14 EPE25741.1 - 0.21 11.0 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Coatomer epsilon subunit Pkinase PF00069.25 EPE25744.1 - 3.9e-25 88.7 0.0 5.5e-13 48.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE25744.1 - 2.2e-11 43.6 0.0 1.5e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EPE25744.1 - 0.025 13.9 0.0 0.37 10.0 0.0 2.4 3 0 0 3 3 3 0 Kinase-like VLPT PF07122.11 EPE25744.1 - 0.048 13.4 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) Nairo_nucleo PF02477.15 EPE25746.1 - 0.23 10.2 0.0 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 Nucleocapsid N protein Peptidase_M20 PF01546.28 EPE25747.1 - 4e-22 78.9 0.0 9.9e-21 74.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EPE25747.1 - 5e-10 39.8 5.0 0.0063 17.3 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat M20_dimer PF07687.14 EPE25747.1 - 4.6e-05 23.3 0.0 9.8e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EPE25747.1 - 0.02 14.6 0.0 0.062 13.0 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M28 PQQ_3 PF13570.6 EPE25747.1 - 3.5 8.2 6.6 1.3 9.6 0.0 3.7 5 0 0 5 5 5 0 PQQ-like domain DUF747 PF05346.11 EPE25748.1 - 2.1e-121 405.3 7.6 2.9e-121 404.9 7.6 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Uso1_p115_head PF04869.14 EPE25749.1 - 5e-115 383.9 0.0 1.4e-114 382.5 0.0 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EPE25749.1 - 3.1e-18 66.4 34.5 3.1e-18 66.4 34.5 3.2 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Atx10homo_assoc PF09759.9 EPE25749.1 - 0.0023 17.9 0.0 1.7 8.7 0.0 3.6 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EPE25749.1 - 0.0047 16.9 0.0 5.5 7.2 0.0 3.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Tti2 PF10521.9 EPE25749.1 - 9.3 5.7 7.4 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Tti2 family XRN_M PF17846.1 EPE25750.1 - 4.8e-144 480.6 0.5 5e-105 352.0 0.0 2.5 3 0 0 3 3 3 2 Xrn1 helical domain XRN_N PF03159.18 EPE25750.1 - 3.9e-101 337.5 0.0 5.6e-101 337.0 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 EPE25750.1 - 0.046 13.8 3.6 0.084 13.0 3.6 1.4 1 0 0 1 1 1 0 Zinc knuckle PS_pyruv_trans PF04230.13 EPE25750.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase UDPG_MGDP_dh_N PF03721.14 EPE25750.1 - 0.24 10.9 0.0 0.44 10.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RasGAP PF00616.19 EPE25751.1 - 7.6e-35 120.5 0.2 1.2e-31 110.1 0.2 2.6 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 EPE25751.1 - 4.1e-06 27.0 0.0 1.1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Novirhabdo_Nv PF05554.11 EPE25751.1 - 0.36 10.6 1.8 6.4 6.5 0.0 3.4 4 0 0 4 4 4 0 Viral hemorrhagic septicemia virus non-virion protein Q_salvage PF10343.9 EPE25752.1 - 2.6e-129 430.8 0.2 3.5e-129 430.4 0.2 1.2 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family zf-3CxxC_2 PF17180.4 EPE25752.1 - 0.44 11.3 3.2 1.1 10.1 0.2 2.9 4 0 0 4 4 4 0 Zinc-binding domain ThiF PF00899.21 EPE25753.1 - 6.8e-68 228.6 0.0 9.6e-68 228.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 EPE25753.1 - 7.7e-27 93.7 1.3 1.1e-26 93.2 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EPE25753.1 - 2.1e-07 31.1 3.7 1.4e-06 28.5 0.1 2.5 1 1 1 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EPE25753.1 - 0.0016 18.8 0.1 0.0046 17.4 0.1 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EPE25753.1 - 0.0084 16.4 0.3 0.037 14.3 0.3 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EPE25753.1 - 0.049 13.7 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 EPE25754.1 - 4.6e-47 160.5 0.5 5.5e-47 160.3 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE25754.1 - 6.6e-46 156.2 0.3 8.4e-46 155.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE25754.1 - 2.6e-06 27.5 0.1 4.6e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE25754.1 - 0.0025 17.3 0.0 0.015 14.8 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.11 EPE25754.1 - 0.2 11.3 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Starch synthase catalytic domain PAP2_3 PF14378.6 EPE25755.1 - 1.1e-18 67.6 14.5 1.1e-18 67.6 14.5 1.7 1 1 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EPE25755.1 - 3.3e-07 30.1 10.7 3.3e-07 30.1 10.7 2.4 1 1 1 2 2 2 1 PAP2 superfamily Skp1_POZ PF03931.15 EPE25756.1 - 1.6e-05 25.0 0.0 0.00091 19.4 0.0 2.2 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain Amidase PF01425.21 EPE25757.1 - 1e-88 298.3 0.0 1.3e-88 297.9 0.0 1.2 1 0 0 1 1 1 1 Amidase DNA_pol_delta_4 PF04081.13 EPE25758.1 - 9.4e-35 119.8 0.5 2.3e-34 118.5 0.5 1.7 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Seryl_tRNA_N PF02403.22 EPE25758.1 - 0.35 11.1 3.9 0.58 10.4 3.9 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Citrate_synt PF00285.21 EPE25759.1 - 2.1e-20 73.1 0.0 2.3e-17 63.1 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 EPE25759.1 - 2.4e-18 66.6 0.0 9.6e-18 64.7 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EPE25759.1 - 2.1e-14 53.6 0.0 3.5e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EPE25759.1 - 1e-05 25.3 0.0 9e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP_sub_h PF10775.9 EPE25759.1 - 0.24 11.4 0.4 0.74 9.8 0.0 1.9 2 0 0 2 2 2 0 ATP synthase complex subunit h Citrate_bind PF16114.5 EPE25760.1 - 4.4e-88 293.4 0.3 6.7e-88 292.8 0.3 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 EPE25760.1 - 6.1e-08 32.5 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Glyco_hydro_72 PF03198.14 EPE25761.1 - 8.1e-115 383.4 0.0 9.9e-115 383.1 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 EPE25761.1 - 0.00082 18.6 0.0 0.0018 17.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain HALZ PF02183.18 EPE25761.1 - 0.12 12.6 1.1 0.61 10.4 0.3 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper Mito_carr PF00153.27 EPE25762.1 - 1.6e-55 185.0 4.4 6.7e-23 80.4 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EPE25762.1 - 1.3e-20 73.7 4.3 1.6e-11 44.4 0.2 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EPE25762.1 - 7.9e-19 65.7 7.1 2.6e-06 26.6 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EPE25762.1 - 2e-17 61.6 7.5 4.8e-05 23.0 0.3 4.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 EPE25762.1 - 1.2e-12 47.5 2.9 0.001 18.8 0.0 3.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EPE25762.1 - 1.8e-12 46.2 7.2 0.00014 21.2 0.1 3.8 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.9 EPE25762.1 - 2.3e-05 24.7 0.0 0.02 15.2 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EPE25762.1 - 0.033 14.5 0.1 5.4 7.4 0.0 3.4 3 1 1 4 4 4 0 EF-hand domain DUF5580 PF17743.1 EPE25762.1 - 0.086 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_10 PF14788.6 EPE25762.1 - 0.6 10.0 3.4 4.3 7.3 0.1 3.2 4 0 0 4 4 4 0 EF hand Cyclin_N PF00134.23 EPE25763.1 - 3e-10 39.9 0.0 7.1e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EPE25763.1 - 0.0048 17.3 0.5 0.018 15.4 0.5 2.0 1 1 0 1 1 1 1 Cyclin C-terminal domain TFIIB PF00382.19 EPE25763.1 - 0.043 13.9 0.3 0.16 12.0 0.3 2.0 1 1 0 1 1 1 0 Transcription factor TFIIB repeat DUF4452 PF14618.6 EPE25765.1 - 1.3e-73 246.5 9.7 1.5e-73 246.2 9.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) SNARE PF05739.19 EPE25767.1 - 2.7e-10 40.1 3.9 5.8e-10 39.0 3.9 1.6 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 EPE25767.1 - 0.0022 17.8 0.9 0.0022 17.8 0.9 1.7 1 1 0 1 1 1 1 Membrane fusion protein Use1 RIFIN PF02009.16 EPE25767.1 - 0.003 17.5 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 Rifin DUF1676 PF07898.13 EPE25767.1 - 0.03 14.4 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) T3SSipB PF16535.5 EPE25767.1 - 0.056 13.9 1.1 0.35 11.3 1.0 2.1 3 0 0 3 3 2 0 Type III cell invasion protein SipB DUF745 PF05335.13 EPE25767.1 - 0.087 12.5 1.5 0.17 11.6 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) UPF0242 PF06785.11 EPE25767.1 - 0.12 12.4 6.2 3.3 7.8 1.6 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus KH_5 PF13184.6 EPE25767.1 - 0.13 12.3 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 NusA-like KH domain ODV-E18 PF10717.9 EPE25767.1 - 0.2 11.5 1.2 0.39 10.6 1.2 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 CENP-H PF05837.12 EPE25767.1 - 0.52 10.7 7.2 2.8 8.4 0.3 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Synaptobrevin PF00957.21 EPE25767.1 - 9.4 6.1 9.8 3.7 7.4 6.2 2.2 2 1 0 2 2 2 0 Synaptobrevin zf-TRAF PF02176.18 EPE25768.1 - 2.6e-10 40.8 28.0 0.00026 21.6 2.9 4.2 2 1 2 4 4 4 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 EPE25768.1 - 8e-08 32.0 8.7 8e-08 32.0 8.7 4.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE25768.1 - 4.7e-07 29.6 6.9 4.7e-07 29.6 6.9 4.6 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE25768.1 - 7.8e-07 29.0 9.2 7.8e-07 29.0 9.2 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 EPE25768.1 - 1.7e-06 28.2 8.2 1.7e-06 28.2 8.2 4.4 3 1 1 4 4 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EPE25768.1 - 2.5e-05 24.0 4.8 2.5e-05 24.0 4.8 4.3 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPE25768.1 - 0.00065 19.8 9.1 0.00065 19.8 9.1 3.3 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EPE25768.1 - 0.0023 17.8 14.4 0.0023 17.8 14.4 4.1 2 2 0 2 2 1 1 zinc-RING finger domain zf-TRAF_2 PF15965.5 EPE25768.1 - 0.0046 17.4 10.9 0.0046 17.4 10.9 3.3 1 1 2 3 3 2 1 TRAF-like zinc-finger zf-RING_6 PF14835.6 EPE25768.1 - 0.0048 16.7 2.8 0.0048 16.7 2.8 2.8 2 1 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 EPE25768.1 - 0.016 15.4 6.4 0.016 15.4 6.4 4.4 4 2 1 5 5 3 0 RING-H2 zinc finger domain U-box PF04564.15 EPE25768.1 - 0.022 14.9 0.0 0.16 12.2 0.1 2.3 3 0 0 3 3 3 0 U-box domain zf-ACC PF17848.1 EPE25768.1 - 0.3 11.2 5.3 7.7 6.7 0.3 3.7 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf-Nse PF11789.8 EPE25768.1 - 0.81 9.5 15.4 1.8 8.4 13.4 2.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ATP_bind_3 PF01171.20 EPE25769.1 - 1.4e-45 155.3 0.0 2.1e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.16 EPE25769.1 - 0.013 14.3 0.3 0.029 13.2 0.0 1.6 2 0 0 2 2 2 0 tRNA methyl transferase NAD_synthase PF02540.17 EPE25769.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Asn_synthase PF00733.21 EPE25769.1 - 0.045 13.4 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase Peptidase_S68 PF10461.9 EPE25769.1 - 0.098 12.9 0.0 0.74 10.1 0.0 2.4 2 0 0 2 2 2 0 Peptidase S68 Mito_carr PF00153.27 EPE25770.1 - 1.7e-48 162.4 7.2 1.2e-18 66.8 0.1 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 EPE25770.1 - 0.22 10.6 1.0 1.9 7.6 1.1 2.2 1 1 0 1 1 1 0 Gammaproteobacterial serine protease DUF3337 PF11816.8 EPE25771.1 - 5.4e-55 185.9 0.0 1.1e-54 184.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EPE25771.1 - 3e-20 72.1 9.8 0.0013 19.5 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 EPE25771.1 - 0.00049 18.9 0.2 0.031 12.9 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EPE25771.1 - 0.0053 17.0 0.5 0.045 14.0 0.1 2.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPE25771.1 - 0.054 12.5 0.0 0.15 11.0 0.0 1.6 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_C48 PF02902.19 EPE25772.1 - 9.3e-21 74.7 0.0 2.2e-20 73.5 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FAD_binding_3 PF01494.19 EPE25773.1 - 3.3e-73 246.9 0.0 4.3e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EPE25773.1 - 5.9e-41 140.3 0.0 1.1e-40 139.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EPE25773.1 - 0.00015 21.2 0.0 0.0096 15.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE25773.1 - 0.0048 16.5 0.1 0.29 10.7 0.0 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE25773.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EPE25773.1 - 0.018 15.6 0.0 0.12 13.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EPE25773.1 - 0.023 14.3 0.1 0.067 12.8 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EPE25773.1 - 0.074 12.7 0.0 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 EPE25773.1 - 0.087 13.3 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Lycopene_cycl PF05834.12 EPE25773.1 - 0.09 11.8 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EPE25773.1 - 0.17 11.1 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family DDHD PF02862.17 EPE25775.1 - 2.8e-24 86.5 0.0 2.8e-24 86.5 0.0 4.7 2 2 0 2 2 2 1 DDHD domain Sda PF08970.10 EPE25775.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Sporulation inhibitor A DSBA PF01323.20 EPE25776.1 - 6.2e-17 62.0 0.0 7.2e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain zf-C2H2 PF00096.26 EPE25779.1 - 8.3e-13 48.0 25.0 0.00028 21.2 2.1 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE25779.1 - 1e-08 35.3 20.1 0.0042 17.8 0.9 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPE25779.1 - 0.013 15.9 21.5 0.018 15.4 2.7 3.9 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EPE25779.1 - 0.28 11.5 10.8 1.5 9.2 0.3 4.0 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-MYST PF17772.1 EPE25779.1 - 0.8 9.4 3.2 2.3 7.9 1.2 2.7 2 1 0 2 2 2 0 MYST family zinc finger domain zf-C2H2_aberr PF17017.5 EPE25779.1 - 2.5 8.2 7.1 3.7 7.7 0.6 2.2 1 1 1 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 EPE25779.1 - 3.8 7.4 14.6 0.16 11.8 2.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain ANAPC4_WD40 PF12894.7 EPE25781.1 - 0.0094 16.2 0.0 1.5 9.2 0.0 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPE25781.1 - 0.03 15.2 0.1 1.8 9.6 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat CNH PF00780.22 EPE25781.1 - 0.13 11.8 0.1 4.1 6.9 0.0 2.9 2 1 1 3 3 3 0 CNH domain Cupin_8 PF13621.6 EPE25782.1 - 1e-33 117.1 0.0 1.8e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 EPE25782.1 - 7.6e-15 55.3 0.0 1.6e-14 54.3 0.0 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 EPE25782.1 - 2.4e-07 30.7 6.7 2.9e-05 24.0 0.1 4.4 4 0 0 4 4 4 1 Galactose oxidase, central domain Cupin_4 PF08007.12 EPE25782.1 - 0.00038 20.0 0.0 0.00071 19.1 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_1 PF01344.25 EPE25782.1 - 0.0026 17.3 7.7 0.66 9.6 0.1 4.1 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 EPE25782.1 - 0.14 12.2 11.0 2.3 8.3 0.1 4.7 6 0 0 6 6 6 0 Kelch motif Kelch_6 PF13964.6 EPE25782.1 - 0.32 11.3 8.2 13 6.2 0.1 4.2 3 1 0 3 3 3 0 Kelch motif MFS_1 PF07690.16 EPE25783.1 - 5.1e-24 84.9 71.9 2.2e-17 63.0 34.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_Rpb1_5 PF04998.17 EPE25784.1 - 8.1e-85 284.5 0.0 1.6e-84 283.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EPE25784.1 - 1.8e-68 230.0 0.3 3.4e-68 229.1 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EPE25784.1 - 1.5e-33 116.0 0.0 4.8e-33 114.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EPE25784.1 - 1e-27 97.3 4.5 4.8e-25 88.6 4.0 4.4 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EPE25784.1 - 9.5e-17 60.9 0.7 4.2e-16 58.8 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DUF2960 PF11173.8 EPE25784.1 - 0.14 12.6 0.0 0.57 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2960) PRP3 PF08572.10 EPE25785.1 - 1.1e-73 247.6 6.3 2.3e-73 246.6 6.3 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EPE25785.1 - 2.6e-51 173.5 1.6 5.6e-51 172.5 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) GET2 PF08690.10 EPE25785.1 - 1.2 8.8 5.8 2.1 8.0 5.8 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 DEAD_2 PF06733.15 EPE25786.1 - 3.1e-55 186.5 0.2 5.1e-55 185.8 0.2 1.3 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 EPE25786.1 - 1.5e-45 155.2 0.6 1.6e-40 138.9 0.1 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EPE25786.1 - 2.1e-43 148.5 0.0 8.2e-43 146.5 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 EPE25786.1 - 0.00019 21.5 0.0 0.0022 18.0 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EPE25786.1 - 0.00093 19.0 0.0 0.23 11.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.23 EPE25786.1 - 0.026 13.2 0.1 0.58 8.8 0.1 2.2 1 1 0 1 1 1 0 SNF2 family N-terminal domain PhoH PF02562.16 EPE25786.1 - 0.077 12.4 0.0 5.6 6.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 EPE25786.1 - 0.13 12.5 0.1 8.5 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain UvrD_C PF13361.6 EPE25786.1 - 0.14 11.5 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DSPc PF00782.20 EPE25787.1 - 1.4e-28 99.4 0.0 1.5e-22 79.8 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EPE25787.1 - 0.0002 21.0 0.1 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EPE25787.1 - 0.011 15.8 0.4 0.13 12.4 0.0 2.7 3 0 0 3 3 3 0 Inositol hexakisphosphate Trypan_PARP PF05887.11 EPE25788.1 - 0.002 18.1 2.5 0.002 18.1 2.5 1.0 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Porin_5 PF16930.5 EPE25788.1 - 0.42 9.1 3.3 0.5 8.8 3.3 1.0 1 0 0 1 1 1 0 Putative porin PepSY PF03413.19 EPE25788.1 - 0.5 11.0 5.2 0.62 10.7 5.2 1.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Pilosulin PF17499.2 EPE25788.1 - 0.85 9.8 3.9 0.99 9.6 3.9 1.1 1 0 0 1 1 1 0 Ant venom peptides NMT1 PF09084.11 EPE25789.1 - 9.8e-77 257.7 0.0 1.3e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EPE25789.1 - 0.0013 18.5 0.0 1.6 8.3 0.0 2.7 3 0 0 3 3 3 2 NMT1-like family RT_RNaseH_2 PF17919.1 EPE25789.1 - 0.086 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase CENP-T_C PF15511.6 EPE25790.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EPE25790.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EPE25790.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EPE25790.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EPE25790.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EPE25790.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EPE25790.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EPE25790.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 EPE25790.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 EPE25791.1 - 4e-52 176.0 2.5 4.5e-52 175.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EPE25791.1 - 6e-06 26.6 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EPE25791.1 - 4e-05 24.2 1.2 4.7e-05 24.0 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EPE25791.1 - 4.3e-05 23.6 0.4 7.4e-05 22.8 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EPE25791.1 - 0.0038 17.5 0.4 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EPE25791.1 - 0.026 14.6 0.2 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Fungal_trans PF04082.18 EPE25792.1 - 7.7e-21 74.3 1.0 1.2e-20 73.7 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RPW8 PF05659.11 EPE25792.1 - 0.02 14.6 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 CheC PF04509.12 EPE25792.1 - 0.098 12.6 0.0 0.57 10.1 0.0 2.3 2 0 0 2 2 2 0 CheC-like family zf-C2H2 PF00096.26 EPE25793.1 - 1.1e-09 38.2 16.0 0.00078 19.8 0.8 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE25793.1 - 3e-07 30.7 7.7 0.012 16.3 0.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 EPE25793.1 - 0.0019 18.4 4.8 0.0042 17.4 1.3 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_12 PF18658.1 EPE25793.1 - 0.017 14.7 3.4 0.046 13.3 2.0 2.2 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf-H2C2_2 PF13465.6 EPE25793.1 - 0.21 12.1 8.1 3.8 8.1 0.8 3.7 3 0 0 3 3 3 0 Zinc-finger double domain Glyco_hydro_76 PF03663.14 EPE25794.1 - 7e-132 440.4 21.1 8.5e-132 440.1 21.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EPE25794.1 - 0.00061 19.0 12.0 0.017 14.2 0.3 3.1 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 p450 PF00067.22 EPE25795.1 - 3.7e-43 147.9 0.0 4e-23 81.9 0.0 2.4 1 1 1 2 2 2 2 Cytochrome P450 Acetyltransf_10 PF13673.7 EPE25796.1 - 2.3e-06 27.6 0.0 3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE25796.1 - 7.6e-06 26.3 0.0 1.2e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE25796.1 - 3.4e-05 24.1 0.0 4.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family NmrA PF05368.13 EPE25797.1 - 5.4e-27 94.8 4.8 6.8e-26 91.3 4.8 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE25797.1 - 1.9e-06 27.9 0.1 3.8e-06 26.9 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Glyco_hydro_53 PF07745.13 EPE25797.1 - 0.012 14.6 1.9 0.4 9.6 0.2 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 53 DUF4267 PF14087.6 EPE25798.1 - 3.7e-17 62.4 6.0 4.4e-17 62.2 6.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) zf-H2C2_2 PF13465.6 EPE25799.1 - 1.3e-10 41.2 13.2 5.3e-05 23.4 3.3 3.9 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 EPE25799.1 - 1.9e-08 34.3 14.0 0.00041 20.6 4.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE25799.1 - 7.2e-05 23.3 11.3 0.047 14.5 3.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE25799.1 - 0.013 15.8 0.4 0.049 13.9 0.4 2.0 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EPE25799.1 - 0.049 14.3 2.2 0.14 12.8 0.2 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain Peptidase_M3 PF01432.20 EPE25800.1 - 2.3e-157 525.0 0.1 3e-157 524.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M2 PF01401.18 EPE25800.1 - 0.059 12.0 0.0 0.17 10.5 0.0 1.7 2 0 0 2 2 2 0 Angiotensin-converting enzyme Rx_N PF18052.1 EPE25800.1 - 0.066 13.5 1.4 0.19 12.0 0.1 2.4 3 0 0 3 3 3 0 Rx N-terminal domain EF-hand_7 PF13499.6 EPE25802.1 - 1.9e-11 44.2 0.7 5.5e-08 33.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EPE25802.1 - 2.7e-08 34.0 0.0 0.012 15.9 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 EPE25802.1 - 3.5e-08 32.7 0.6 0.015 15.2 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EPE25802.1 - 2.5e-07 29.7 0.1 0.028 14.0 0.0 3.6 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EPE25802.1 - 8.3e-06 25.6 0.1 0.00013 21.8 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair DUF3216 PF11505.8 EPE25802.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Methyltransf_11 PF08241.12 EPE25803.1 - 1.2e-16 61.1 0.0 1.8e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE25803.1 - 8.2e-16 58.5 0.0 1.7e-15 57.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE25803.1 - 2.9e-10 40.8 0.0 4.8e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE25803.1 - 7.7e-10 38.8 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE25803.1 - 6.3e-06 25.7 0.0 1.9e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 EPE25803.1 - 2.4e-05 23.5 0.0 4.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 EPE25803.1 - 6.6e-05 22.8 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPE25803.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 EPE25803.1 - 0.035 13.1 0.0 0.051 12.6 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase RrnaAD PF00398.20 EPE25803.1 - 0.16 11.1 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CoA_binding_2 PF13380.6 EPE25804.1 - 8e-27 94.0 0.0 1.1e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain DUF4407 PF14362.6 EPE25805.1 - 0.13 11.6 3.6 0.16 11.3 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.13 EPE25805.1 - 0.56 10.8 16.9 14 6.4 16.9 2.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Presenilin PF01080.17 EPE25805.1 - 0.95 8.1 4.4 1.1 7.9 4.4 1.0 1 0 0 1 1 1 0 Presenilin Usp PF00582.26 EPE25805.1 - 1.6 9.2 5.6 2.2 8.8 5.6 1.1 1 0 0 1 1 1 0 Universal stress protein family MFS_1_like PF12832.7 EPE25805.1 - 5.2 5.8 5.2 7.3 5.3 5.2 1.1 1 0 0 1 1 1 0 MFS_1 like family OmpH PF03938.14 EPE25805.1 - 7.9 6.8 18.6 11 6.3 18.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Glyco_hydro_3_C PF01915.22 EPE25806.1 - 1.4e-52 178.7 0.0 2.9e-52 177.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE25806.1 - 4e-40 138.1 0.0 7e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE25806.1 - 2.7e-25 88.2 0.1 5.7e-25 87.2 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Sec62 PF03839.16 EPE25808.1 - 5.6e-74 248.3 0.2 5.6e-74 248.3 0.2 1.7 2 0 0 2 2 2 1 Translocation protein Sec62 Lectin_C PF00059.21 EPE25809.1 - 0.019 15.7 4.9 0.37 11.6 0.3 2.8 3 0 0 3 3 3 0 Lectin C-type domain RhoGAP PF00620.27 EPE25810.1 - 1.9e-44 151.2 2.0 2.5e-44 150.8 0.0 2.2 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.22 EPE25810.1 - 1e-13 51.3 16.9 5.1e-09 36.2 1.6 2.4 2 0 0 2 2 2 2 LIM domain zf-ribbon_3 PF13248.6 EPE25810.1 - 0.025 14.0 7.7 1.1 8.8 0.0 3.7 3 1 0 3 3 3 0 zinc-ribbon domain DUF848 PF05852.11 EPE25810.1 - 1.6 8.9 9.1 0.49 10.5 2.9 2.5 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Desulfoferrod_N PF06397.12 EPE25810.1 - 7.5 6.3 8.6 18 5.1 0.9 3.4 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain CLASP_N PF12348.8 EPE25811.1 - 1.4e-130 433.7 0.6 4.8e-91 304.3 0.0 2.4 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 EPE25811.1 - 3.3e-05 23.8 0.2 0.48 10.8 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 EPE25811.1 - 5.6e-05 23.2 0.0 0.42 10.6 0.1 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EPE25811.1 - 0.064 11.8 0.3 0.28 9.7 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region BSP PF04450.12 EPE25812.1 - 2.7e-75 252.7 0.0 3.1e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 EPE25812.1 - 0.0017 18.2 0.2 0.0026 17.6 0.2 1.4 1 1 0 1 1 1 1 SprT-like family DUF1850 PF08905.11 EPE25812.1 - 0.019 15.3 0.1 0.72 10.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1850) Peptidase_M91 PF14891.6 EPE25812.1 - 0.044 14.1 0.0 0.074 13.4 0.0 1.4 1 0 0 1 1 1 0 Effector protein rRNA_processing PF08524.11 EPE25814.1 - 2.6e-07 30.8 20.7 8e-07 29.2 20.7 1.7 1 1 0 1 1 1 1 rRNA processing Med3 PF11593.8 EPE25814.1 - 0.034 13.3 4.5 0.042 13.0 4.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1682 PF07946.14 EPE25814.1 - 8.1 5.6 12.6 10 5.2 12.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4210 PF13915.6 EPE25815.1 - 1.1e-33 115.6 0.1 3.1e-33 114.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 EPE25815.1 - 7.9e-21 74.0 0.5 1.8e-20 72.8 0.5 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis PPR_2 PF13041.6 EPE25816.1 - 3.2e-15 56.0 1.6 0.00042 20.5 0.0 7.0 7 1 1 8 8 8 4 PPR repeat family PPR_3 PF13812.6 EPE25816.1 - 8.7e-10 38.5 0.0 0.024 14.7 0.0 5.6 4 1 2 6 6 6 4 Pentatricopeptide repeat domain PPR PF01535.20 EPE25816.1 - 5e-08 32.7 1.4 3.9 7.9 0.0 8.0 9 0 0 9 9 9 2 PPR repeat PPR_long PF17177.4 EPE25816.1 - 0.0021 17.5 0.2 0.2 11.0 0.2 3.1 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EPE25816.1 - 0.06 14.2 3.8 13 6.9 0.0 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat SRP68 PF16969.5 EPE25817.1 - 7.3e-201 669.0 2.9 8.7e-201 668.7 2.9 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 PMEI PF04043.15 EPE25817.1 - 0.073 13.4 8.2 0.17 12.3 1.8 3.1 3 0 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor DUF1040 PF06288.13 EPE25817.1 - 0.11 12.9 0.1 0.38 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) CENP-O PF09496.10 EPE25817.1 - 0.87 9.5 3.2 2.2 8.2 1.3 2.4 1 1 1 2 2 2 0 Cenp-O kinetochore centromere component Mo-co_dimer PF03404.16 EPE25818.1 - 1.9e-58 196.4 1.0 3.6e-58 195.5 1.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 EPE25818.1 - 9e-55 184.9 0.0 1.5e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 EPE25818.1 - 9.1e-35 119.0 0.0 1.6e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EPE25818.1 - 2.9e-26 92.2 0.0 2.3e-25 89.3 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 EPE25818.1 - 1.2e-21 76.6 0.1 3.4e-21 75.2 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EPE25818.1 - 0.002 18.3 0.1 0.14 12.3 0.0 2.4 1 1 0 2 2 2 1 Ferric reductase NAD binding domain MIF4G PF02854.19 EPE25819.1 - 1.9e-59 200.9 0.0 1.9e-28 99.5 0.0 3.3 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 EPE25819.1 - 1.1e-40 139.5 5.9 1.1e-40 139.5 5.9 2.7 2 0 0 2 2 2 1 Up-frameshift suppressor 2 TCTP PF00838.17 EPE25819.1 - 0.4 11.0 2.8 0.69 10.2 0.1 2.4 2 0 0 2 2 2 0 Translationally controlled tumour protein Red1 PF07964.11 EPE25819.1 - 5.5 5.1 9.0 15 3.7 0.0 2.2 2 0 0 2 2 2 0 Rec10 / Red1 Chitin_synth_2 PF03142.15 EPE25820.1 - 4.9e-24 84.9 13.8 2e-23 82.8 2.9 2.6 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EPE25820.1 - 6.4e-16 58.9 3.2 6.4e-16 58.9 3.2 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EPE25820.1 - 5.4e-11 42.8 0.0 1.1e-10 41.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EPE25820.1 - 0.0057 16.5 0.3 3 7.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Ribosomal_S19e PF01090.19 EPE25821.1 - 2.5e-58 195.7 0.1 2.8e-58 195.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Fmp27 PF10344.9 EPE25822.1 - 6.7e-226 752.4 0.0 1e-225 751.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 EPE25822.1 - 3.7e-205 682.3 8.6 3.7e-205 682.3 8.6 3.1 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 EPE25822.1 - 5.8e-190 632.3 5.2 1.3e-189 631.1 5.2 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 EPE25822.1 - 8.6e-59 198.1 0.5 1.8e-58 197.0 0.1 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EPE25822.1 - 9.3e-57 191.3 0.1 2.1e-56 190.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EPE25822.1 - 7.1e-35 119.8 0.0 6e-34 116.8 0.0 2.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Stig1 PF04885.13 EPE25823.1 - 2.4e-05 24.9 20.0 2.4e-05 24.9 20.0 2.7 1 1 1 2 2 2 1 Stigma-specific protein, Stig1 Zn_clus PF00172.18 EPE25824.1 - 2.3e-09 37.2 10.1 4.2e-09 36.4 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE25824.1 - 3.2e-06 26.2 0.0 4.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF521 PF04412.13 EPE25824.1 - 0.005 15.6 0.0 0.0074 15.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF521) p450 PF00067.22 EPE25825.1 - 2.6e-76 257.2 0.0 9.7e-76 255.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 NPAT_C PF15712.5 EPE25825.1 - 0.37 9.4 0.0 0.37 9.4 0.0 1.4 2 0 0 2 2 2 0 NPAT C terminus DUF1932 PF09130.11 EPE25826.1 - 1.8e-22 79.1 0.0 3.8e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 EPE25826.1 - 1.7e-06 28.3 0.0 3.9e-06 27.1 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EPE25826.1 - 6.3e-06 26.7 0.1 1.2e-05 25.8 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EPE25826.1 - 0.0075 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EPE25826.1 - 0.046 13.6 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RRM_1 PF00076.22 EPE25827.1 - 1.2e-18 66.7 0.0 1.8e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EPE25827.1 - 4.1e-09 36.9 12.6 4.1e-09 36.9 12.6 2.7 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 TPR_8 PF13181.6 EPE25828.1 - 4.1e-09 35.9 1.6 0.0047 17.0 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPE25828.1 - 1.3e-08 34.3 5.4 0.0024 17.9 0.1 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPE25828.1 - 4.4e-08 33.3 3.0 0.066 13.5 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EPE25828.1 - 6.9e-08 33.0 0.7 0.011 16.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE25828.1 - 4.1e-07 30.1 0.0 2.8e-06 27.5 0.0 2.5 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EPE25828.1 - 1.9e-05 25.1 0.1 0.11 13.4 0.1 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPE25828.1 - 3.2e-05 24.3 6.3 0.02 15.4 0.3 3.1 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EPE25828.1 - 5.2e-05 22.9 6.5 0.013 15.3 0.1 4.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 EPE25828.1 - 0.00037 20.3 1.0 0.00037 20.3 1.0 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 EPE25828.1 - 0.00068 20.0 0.0 6.9 7.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EPE25828.1 - 0.0019 18.0 9.6 1.7 8.7 0.0 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EPE25828.1 - 0.0047 16.6 2.1 2.3 8.0 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.6 EPE25828.1 - 0.0054 17.0 1.7 2.6 8.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC5 PF12862.7 EPE25828.1 - 0.016 15.3 0.3 0.53 10.4 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 EPE25828.1 - 0.016 14.6 3.0 0.061 12.7 0.5 2.3 2 1 0 2 2 2 0 MalT-like TPR region TPR_7 PF13176.6 EPE25828.1 - 0.037 14.0 3.2 0.82 9.8 0.1 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TFR_dimer PF04253.15 EPE25828.1 - 0.053 13.6 0.0 0.3 11.2 0.0 2.2 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain TPR_6 PF13174.6 EPE25828.1 - 0.43 11.3 5.0 9.5 7.1 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ADH_zinc_N_2 PF13602.6 EPE25829.1 - 2.2e-15 57.9 0.0 4.2e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPE25829.1 - 2.3e-12 47.0 0.0 3.9e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 EPE25829.1 - 0.00072 19.4 0.0 0.42 10.3 0.0 3.0 2 1 0 3 3 3 1 Protein of unknown function (DUF2855) ADH_N PF08240.12 EPE25829.1 - 0.042 13.7 0.0 0.59 10.0 0.0 2.6 1 1 2 3 3 3 0 Alcohol dehydrogenase GroES-like domain CBFD_NFYB_HMF PF00808.23 EPE25830.1 - 2.5e-15 56.5 0.8 4.3e-15 55.7 0.8 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EPE25830.1 - 0.0011 19.3 0.0 0.0011 19.3 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Acetyltransf_9 PF13527.7 EPE25831.1 - 0.00026 21.1 0.0 0.00054 20.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE25831.1 - 0.15 12.3 0.0 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE25831.1 - 0.19 11.7 0.0 0.66 9.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Peptidase_C15 PF01470.17 EPE25833.1 - 2.2e-17 63.9 0.0 2.7e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Pyroglutamyl peptidase Pkinase PF00069.25 EPE25834.1 - 3e-25 89.1 0.0 1.4e-24 86.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE25834.1 - 2.8e-07 30.1 0.0 5.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AMP-binding PF00501.28 EPE25835.1 - 1.3e-58 198.6 0.0 1.8e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE25835.1 - 4.9e-06 27.4 0.0 1e-05 26.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.23 EPE25836.1 - 1.6e-60 204.7 0.2 2.2e-60 204.2 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EPE25836.1 - 2.2e-45 153.2 0.1 4.7e-45 152.2 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EPE25836.1 - 0.001 18.9 0.3 0.11 12.4 0.2 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 EPE25836.1 - 0.0017 18.5 0.2 0.0056 16.8 0.0 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 EPE25836.1 - 0.0089 15.6 1.2 0.075 12.6 1.8 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.6 EPE25837.1 - 6.6e-53 179.7 1.3 9.8e-52 175.8 1.3 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE25837.1 - 1.2e-37 129.3 1.3 3.7e-37 127.7 1.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE25837.1 - 5.2e-10 39.5 1.3 2.4e-09 37.4 0.3 2.1 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EPE25837.1 - 0.052 12.7 0.0 0.096 11.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ketoacyl-synt PF00109.26 EPE25838.1 - 1.9e-71 240.6 0.0 4.7e-71 239.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EPE25838.1 - 2.9e-55 187.6 0.0 4.6e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EPE25838.1 - 2.6e-51 174.1 0.3 1.3e-50 171.8 0.0 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EPE25838.1 - 1.1e-47 163.1 0.0 1.8e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE25838.1 - 1.3e-37 128.4 0.2 3.3e-37 127.1 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EPE25838.1 - 2e-19 70.1 0.0 5.1e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 EPE25838.1 - 3.6e-13 49.6 0.0 1.5e-12 47.6 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE25838.1 - 1.3e-09 39.2 0.0 5.1e-09 37.3 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EPE25838.1 - 2.5e-09 36.9 0.2 2.3e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.25 EPE25838.1 - 2.4e-07 31.0 0.2 7.4e-07 29.4 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 EPE25838.1 - 1.3e-05 24.9 0.0 3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ACP_syn_III PF08545.10 EPE25838.1 - 0.00019 21.2 0.1 0.0017 18.2 1.1 2.2 2 0 0 2 2 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.12 EPE25838.1 - 0.00021 21.1 0.1 0.00051 19.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EPE25838.1 - 0.0039 16.6 0.2 0.012 15.0 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain DNA_gyraseB_C PF00986.21 EPE25838.1 - 0.12 12.6 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 DNA gyrase B subunit, carboxyl terminus Zn_clus PF00172.18 EPE25839.1 - 2.3e-07 30.8 13.5 4.3e-07 30.0 13.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE25839.1 - 8.7e-07 28.2 0.3 1.9e-06 27.1 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4646 PF15496.6 EPE25841.1 - 0.012 16.2 0.2 0.031 14.9 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4646) S6OS1 PF15676.5 EPE25841.1 - 0.28 9.6 1.6 0.46 8.9 1.6 1.3 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Zn_clus PF00172.18 EPE25842.1 - 9.3e-11 41.7 12.7 1.9e-10 40.7 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Velvet PF11754.8 EPE25843.1 - 1.6e-51 175.6 3.9 7.4e-35 121.1 0.1 3.4 2 2 1 3 3 3 2 Velvet factor DUF4611 PF15387.6 EPE25843.1 - 0.022 15.0 3.2 0.04 14.1 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Pkinase PF00069.25 EPE25844.1 - 5.5e-44 150.5 0.0 6.2e-43 147.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE25844.1 - 8.8e-33 113.7 0.0 1.2e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EPE25844.1 - 0.00084 18.7 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPE25844.1 - 0.00087 18.7 0.0 0.0038 16.6 0.0 2.0 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 EPE25844.1 - 0.01 15.7 0.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family CTP_synth_N PF06418.14 EPE25845.1 - 1.3e-93 313.2 0.0 1.7e-93 312.8 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EPE25845.1 - 2.5e-57 193.7 0.0 3.9e-57 193.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EPE25845.1 - 8.5e-08 32.2 0.0 2.9e-07 30.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 KRAB PF01352.27 EPE25845.1 - 0.13 11.9 0.2 0.36 10.5 0.2 1.7 1 0 0 1 1 1 0 KRAB box YukD PF08817.10 EPE25846.1 - 0.077 13.7 0.0 0.2 12.3 0.0 1.7 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD DUF2827 PF10933.8 EPE25846.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) PI3_PI4_kinase PF00454.27 EPE25847.1 - 7.1e-37 127.6 0.0 5.4e-36 124.7 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 EPE25847.1 - 6.5e-20 70.8 0.1 1.5e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 EPE25847.1 - 0.006 16.0 1.4 0.011 15.1 1.4 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CopC PF04234.12 EPE25848.1 - 0.05 14.7 0.1 0.15 13.1 0.1 1.8 1 0 0 1 1 1 0 CopC domain Zn_clus PF00172.18 EPE25849.1 - 1.7e-09 37.6 7.2 6.3e-09 35.8 7.2 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE25849.1 - 1.1e-08 34.4 7.4 2.3e-08 33.4 7.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain IF-2B PF01008.17 EPE25850.1 - 6.1e-76 255.3 3.6 6.3e-75 252.0 3.6 1.9 1 1 0 1 1 1 1 Initiation factor 2 subunit family SMC_N PF02463.19 EPE25851.1 - 2.3e-67 226.6 4.0 5.7e-67 225.4 4.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EPE25851.1 - 7.6e-27 94.0 0.1 3.6e-26 91.8 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EPE25851.1 - 8.7e-17 61.9 4.8 7.5e-09 35.8 0.3 3.3 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EPE25851.1 - 3.4e-15 56.6 52.7 1.1e-12 48.3 17.3 4.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 EPE25851.1 - 7.5e-13 49.4 26.6 7.5e-13 49.4 26.6 8.1 2 2 3 6 6 6 1 AAA domain Atg14 PF10186.9 EPE25851.1 - 0.0035 16.5 11.9 0.0035 16.5 11.9 5.1 2 2 2 5 5 5 1 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_29 PF13555.6 EPE25851.1 - 0.005 16.6 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EPE25851.1 - 0.06 13.6 0.1 0.56 10.5 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 EPE25851.1 - 0.08 13.4 0.3 2.1 8.8 0.0 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EPE25851.1 - 0.32 11.5 0.0 0.32 11.5 0.0 5.9 3 2 0 3 3 3 0 ABC transporter Cupin_2 PF07883.11 EPE25852.1 - 6.6e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 EPE25852.1 - 0.096 12.4 0.1 0.16 11.7 0.0 1.4 1 1 0 1 1 1 0 Cupin Peptidase_S8 PF00082.22 EPE25853.1 - 1.7e-30 106.3 18.1 3.8e-30 105.2 18.1 1.5 1 1 0 1 1 1 1 Subtilase family Pribosyltran PF00156.27 EPE25854.1 - 3.8e-18 65.5 0.0 5.4e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 EPE25854.1 - 0.0022 17.5 0.0 0.0042 16.6 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase MFS_1 PF07690.16 EPE25855.1 - 1.4e-26 93.3 31.2 9.6e-26 90.5 28.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1996 PF09362.10 EPE25858.1 - 9.9e-80 267.9 1.5 1.2e-79 267.6 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Cu_amine_oxid PF01179.20 EPE25859.1 - 3.1e-164 546.8 0.1 3.8e-164 546.5 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EPE25859.1 - 3.2e-07 30.7 0.0 6.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EPE25859.1 - 0.0003 21.0 0.0 0.0006 20.0 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain AA_permease_2 PF13520.6 EPE25860.1 - 2.1e-63 214.6 39.0 2.6e-63 214.3 39.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE25860.1 - 8.1e-25 87.3 32.4 1.1e-24 86.9 32.4 1.1 1 0 0 1 1 1 1 Amino acid permease Amidohydro_2 PF04909.14 EPE25861.1 - 1.6e-42 146.3 0.0 2.3e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.18 EPE25861.1 - 2.8e-21 75.8 0.0 4.4e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE25861.1 - 0.2 11.8 3.5 0.39 10.9 3.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Polyketide_cyc2 PF10604.9 EPE25862.1 - 1.9e-07 31.5 0.0 2.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Cyclin_C_2 PF16899.5 EPE25864.1 - 1.9e-30 105.3 3.0 2.3e-28 98.6 0.0 2.7 3 1 0 3 3 3 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EPE25864.1 - 1e-06 28.5 0.1 3.5e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain FAD_binding_4 PF01565.23 EPE25867.1 - 6.2e-18 64.9 0.1 1.2e-17 63.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE25867.1 - 6.7e-07 29.3 1.0 2.2e-06 27.7 1.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.10 EPE25867.1 - 0.081 12.3 0.8 0.14 11.5 0.8 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding TyeA PF09059.10 EPE25867.1 - 0.087 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 TyeA Sortilin-Vps10 PF15902.5 EPE25868.1 - 1.3e-09 37.4 3.8 0.0034 16.2 0.1 5.1 4 2 1 5 5 5 3 Sortilin, neurotensin receptor 3, CBM_1 PF00734.18 EPE25868.1 - 1.2e-08 34.8 6.3 3.2e-08 33.4 6.3 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.20 EPE25868.1 - 6.6e-07 28.4 20.9 1.2 9.4 0.1 7.6 7 0 0 7 7 7 5 BNR/Asp-box repeat BNR_6 PF15899.5 EPE25868.1 - 8.9e-06 25.3 16.4 0.23 11.6 0.0 7.5 8 0 0 8 8 8 3 BNR-Asp box repeat Kelch_3 PF13415.6 EPE25868.1 - 0.42 11.0 9.9 3.1 8.2 0.2 4.2 3 0 0 3 3 3 0 Galactose oxidase, central domain DNA_pol_A_exo1 PF01612.20 EPE25870.1 - 0.0041 16.8 0.2 0.042 13.6 0.0 2.2 2 0 0 2 2 2 1 3'-5' exonuclease DUF87 PF01935.17 EPE25871.1 - 0.0034 17.5 0.0 0.065 13.3 0.0 2.3 1 1 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 EPE25871.1 - 0.011 16.0 0.0 0.57 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EPE25871.1 - 0.012 15.4 0.5 0.089 12.6 0.0 2.2 1 1 1 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EPE25871.1 - 0.014 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zot PF05707.12 EPE25871.1 - 0.018 14.7 0.0 0.053 13.2 0.0 1.8 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Zeta_toxin PF06414.12 EPE25871.1 - 0.071 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TauD PF02668.16 EPE25872.1 - 1.7e-33 116.6 0.1 2.7e-33 115.9 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EPE25872.1 - 4.3e-13 49.7 1.7 5.9e-13 49.3 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF971) UQ_con PF00179.26 EPE25874.1 - 2.1e-42 144.1 0.0 3.2e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EPE25874.1 - 1.7e-06 27.7 0.3 3.6e-06 26.7 0.3 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 EPE25874.1 - 0.0025 17.5 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EPE25874.1 - 0.0075 16.5 0.1 0.047 14.0 0.0 2.1 2 0 0 2 2 2 1 RWD domain DUF1421 PF07223.11 EPE25874.1 - 0.026 14.4 0.1 0.052 13.4 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain (DUF1421) UEV PF05743.13 EPE25874.1 - 0.061 13.2 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 UEV domain UBA PF00627.31 EPE25874.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Tail_tube PF10618.9 EPE25874.1 - 0.17 11.8 0.0 22 5.0 0.0 2.3 2 0 0 2 2 2 0 Phage tail tube protein AAA PF00004.29 EPE25875.1 - 1.4e-41 142.0 0.0 2.3e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EPE25875.1 - 1.3e-11 44.3 0.2 2.5e-11 43.4 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EPE25875.1 - 1.1e-10 41.2 0.6 1.9e-10 40.3 0.6 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EPE25875.1 - 1.2e-06 28.7 0.0 2.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EPE25875.1 - 4.9e-06 26.9 0.1 0.02 15.1 0.1 2.7 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 EPE25875.1 - 1.2e-05 24.6 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EPE25875.1 - 5.3e-05 23.2 0.1 0.00018 21.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EPE25875.1 - 0.00026 20.8 0.0 0.00053 19.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EPE25875.1 - 0.00032 21.1 0.2 0.0059 17.0 0.2 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EPE25875.1 - 0.00078 20.0 0.0 0.0015 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 EPE25875.1 - 0.00099 18.7 0.3 0.0071 16.0 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 EPE25875.1 - 0.0032 17.7 0.5 0.0077 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EPE25875.1 - 0.0056 16.9 0.0 0.027 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EPE25875.1 - 0.014 15.4 0.1 0.63 9.9 0.1 2.4 1 1 1 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 EPE25875.1 - 0.015 15.1 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 EPE25875.1 - 0.017 15.1 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EPE25875.1 - 0.018 14.9 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 EPE25875.1 - 0.03 13.5 0.8 0.057 12.6 0.1 1.8 2 1 0 2 2 2 0 TIP49 P-loop domain RNA_helicase PF00910.22 EPE25875.1 - 0.051 14.0 0.0 0.097 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EPE25875.1 - 0.063 12.6 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EPE25875.1 - 0.065 12.6 0.2 0.6 9.4 0.1 2.2 1 1 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 EPE25875.1 - 0.069 12.4 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 EPE25875.1 - 0.096 12.4 0.4 0.31 10.8 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EPE25875.1 - 0.11 12.1 1.3 0.55 9.8 0.4 2.3 1 1 1 2 2 2 0 AAA domain PhoH PF02562.16 EPE25875.1 - 0.15 11.5 0.3 0.52 9.7 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 EPE25875.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 EPE25875.1 - 0.21 11.1 0.1 0.52 9.8 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region CortBP2 PF09727.9 EPE25876.1 - 0.031 14.2 5.8 0.045 13.7 5.8 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 LPP PF04728.13 EPE25876.1 - 0.13 12.7 2.8 11 6.5 0.4 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper NPR1_interact PF15699.5 EPE25876.1 - 0.16 12.6 1.6 0.88 10.2 0.2 2.3 2 1 0 2 2 2 0 NPR1 interacting DUF4595 PF15283.6 EPE25877.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4595) with porin-like fold ScdA_N PF04405.14 EPE25877.1 - 0.2 11.3 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) Adap_comp_sub PF00928.21 EPE25878.1 - 3.6e-85 285.5 0.0 4.5e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EPE25878.1 - 0.00014 21.8 0.2 0.00027 20.9 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RIBIOP_C PF04950.12 EPE25878.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal muHD PF10291.9 EPE25878.1 - 0.042 13.3 0.2 0.072 12.5 0.2 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain CoA_binding PF02629.19 EPE25879.1 - 1.4e-26 93.0 1.9 1.4e-26 93.0 1.9 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EPE25879.1 - 1e-24 87.1 0.3 1.7e-24 86.4 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EPE25879.1 - 1.6e-09 37.7 0.1 2.9e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EPE25879.1 - 0.00037 21.0 0.1 0.0012 19.4 0.1 1.9 2 0 0 2 2 2 1 CoA binding domain Radical_SAM_C PF16199.5 EPE25880.1 - 3.4e-32 110.3 0.0 6.6e-32 109.4 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EPE25880.1 - 9.1e-17 61.9 0.1 4e-16 59.8 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EPE25880.1 - 1.7e-11 44.4 0.0 3.3e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE25880.1 - 3.1e-06 27.2 0.0 8.9e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE25880.1 - 0.0086 16.5 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HET PF06985.11 EPE25881.1 - 2.6e-20 73.2 0.5 5.1e-20 72.3 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CFEM PF05730.11 EPE25882.1 - 0.018 15.1 4.4 0.028 14.5 3.4 1.8 1 1 1 2 2 2 0 CFEM domain GFO_IDH_MocA PF01408.22 EPE25883.1 - 3.3e-21 76.3 0.1 6e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EPE25883.1 - 9.8e-13 48.1 0.0 1.7e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain OCD_Mu_crystall PF02423.15 EPE25883.1 - 0.0065 15.4 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family DapB_N PF01113.20 EPE25883.1 - 0.017 15.2 0.1 0.029 14.5 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Abhydrolase_6 PF12697.7 EPE25884.1 - 1.7e-10 41.9 0.0 2.5e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE25884.1 - 2e-08 33.8 3.0 2e-08 33.8 0.1 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE25884.1 - 0.0036 17.0 0.2 0.0087 15.7 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold BCNT PF07572.12 EPE25885.1 - 5.3e-22 77.7 1.3 5.3e-22 77.7 1.3 1.9 2 0 0 2 2 2 1 Bucentaur or craniofacial development Dus PF01207.17 EPE25887.1 - 4e-59 200.2 0.0 1.1e-58 198.8 0.0 1.7 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EPE25887.1 - 0.005 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Imm39 PF15568.6 EPE25887.1 - 0.031 14.4 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 39 Lge1 PF11488.8 EPE25893.1 - 0.27 11.4 2.6 1.4 9.2 1.1 2.5 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Pectate_lyase_3 PF12708.7 EPE25894.1 - 3.6e-99 331.0 22.5 1.5e-87 293.0 9.9 3.4 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EPE25894.1 - 1.8e-06 27.6 2.0 0.0096 15.6 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Period_C PF12114.8 EPE25894.1 - 0.17 11.5 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region EB1 PF03271.17 EPE25895.1 - 1.8e-16 60.1 1.6 3.7e-16 59.1 1.6 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EPE25895.1 - 1.5e-07 31.6 0.4 2.6e-07 30.8 0.4 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Suppressor_APC PF11414.8 EPE25895.1 - 0.031 14.3 0.6 0.065 13.3 0.6 1.5 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein CH_2 PF06294.11 EPE25895.1 - 0.058 13.5 0.1 0.094 12.8 0.1 1.3 1 0 0 1 1 1 0 CH-like domain in sperm protein Syja_N PF02383.18 EPE25895.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain PX PF00787.24 EPE25896.1 - 9.7e-15 54.5 0.0 1.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.19 EPE25896.1 - 0.17 11.9 0.7 0.74 9.9 0.6 2.2 2 0 0 2 2 2 0 SNARE domain Inhibitor_I36 PF03995.13 EPE25897.1 - 0.002 18.0 0.7 0.0053 16.7 0.1 1.8 2 0 0 2 2 2 1 Peptidase inhibitor family I36 NAD_binding_10 PF13460.6 EPE25898.1 - 6.9e-18 65.2 0.0 1.2e-16 61.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EPE25898.1 - 3.9e-11 42.9 0.0 1.5e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPE25898.1 - 4.8e-06 26.3 0.0 1.2e-05 25.0 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EPE25898.1 - 9.3e-05 22.7 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 EPE25898.1 - 0.00012 21.6 0.1 0.0002 20.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EPE25898.1 - 0.00013 21.1 0.1 0.00019 20.6 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EPE25898.1 - 0.0015 17.6 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EPE25898.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EPE25898.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 EPE25898.1 - 0.02 14.0 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 EPE25898.1 - 0.025 14.9 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.20 EPE25898.1 - 0.034 14.3 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 EPE25898.1 - 0.054 12.7 0.0 0.096 11.8 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein MFS_1 PF07690.16 EPE25899.1 - 4.3e-28 98.3 56.0 1.7e-27 96.3 52.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE25899.1 - 4.9e-11 42.2 12.6 4.9e-11 42.2 12.6 3.0 1 1 1 3 3 3 1 Sugar (and other) transporter ADH_N PF08240.12 EPE25900.1 - 1.2e-25 89.5 3.4 2e-25 88.8 3.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE25900.1 - 2.1e-13 50.4 0.0 5e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EPE25900.1 - 0.00013 21.3 0.3 0.00024 20.5 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EPE25900.1 - 0.18 11.1 0.1 0.54 9.5 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain zf-HC5HC2H_2 PF13832.6 EPE25901.1 - 4.1e-32 110.6 6.5 4.1e-32 110.6 6.5 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 EPE25901.1 - 9e-29 100.9 0.0 5.7e-28 98.3 0.0 2.4 3 1 0 3 3 3 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 EPE25901.1 - 1.4e-25 89.4 6.3 1.4e-25 89.4 6.3 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EPE25901.1 - 2.1e-14 52.8 1.7 2.1e-14 52.8 1.7 2.0 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EPE25901.1 - 1.5e-08 34.4 23.0 2.1e-08 33.9 9.1 2.7 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 EPE25901.1 - 6.4 6.4 13.5 0.034 13.7 2.6 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 EPE25901.1 - 6.6 6.7 15.7 0.81 9.6 2.7 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) WD40 PF00400.32 EPE25903.1 - 4.4e-30 103.3 17.0 1.6e-07 31.9 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE25903.1 - 4.4e-09 36.5 0.1 0.0007 19.8 0.0 5.0 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 EPE25903.1 - 3.7e-08 33.1 0.6 9e-08 31.9 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE25903.1 - 2.3e-06 27.3 0.1 4.7e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EPE25903.1 - 3.1e-06 26.1 0.8 0.0088 14.7 0.1 3.6 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EPE25903.1 - 0.0048 15.9 0.2 0.49 9.3 0.1 2.7 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EPE25903.1 - 0.0092 15.3 0.5 3.1 7.0 0.0 3.1 2 1 1 3 3 3 1 WD40-like domain Ribosomal_S7e PF01251.18 EPE25904.1 - 3.6e-82 274.6 0.2 4.3e-82 274.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.13 EPE25905.1 - 2.2e-214 712.6 0.1 2.9e-214 712.3 0.1 1.1 1 0 0 1 1 1 1 Dynactin p62 family Mu-like_Com PF10122.9 EPE25905.1 - 0.19 11.2 4.9 4.3 6.9 2.0 3.1 2 0 0 2 2 2 0 Mu-like prophage protein Com Glyco_hydro_cc PF11790.8 EPE25906.1 - 9e-61 205.5 6.6 1.1e-60 205.2 6.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF5133 PF17196.4 EPE25907.1 - 0.061 13.5 0.1 0.18 12.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF5133) SMC_N PF02463.19 EPE25908.1 - 2e-51 174.5 24.1 9.3e-50 169.1 24.1 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EPE25908.1 - 1.9e-25 89.4 0.0 7.1e-25 87.6 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EPE25908.1 - 2.6e-09 37.3 12.6 4.2e-05 23.5 0.1 3.9 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EPE25908.1 - 5.2e-08 32.5 0.0 1.1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EPE25908.1 - 1.5e-06 28.2 17.9 1.5e-06 28.2 17.9 4.7 1 1 3 4 4 2 1 AAA ATPase domain AAA_13 PF13166.6 EPE25908.1 - 1.5e-05 23.9 16.2 1.5e-05 23.9 16.2 5.8 3 2 2 5 5 5 2 AAA domain Spc7 PF08317.11 EPE25908.1 - 1.7e-05 23.8 13.8 1.7e-05 23.8 13.8 7.4 3 2 3 7 7 7 5 Spc7 kinetochore protein AAA_23 PF13476.6 EPE25908.1 - 0.00086 19.9 40.4 0.00086 19.9 40.4 7.1 2 2 1 3 3 2 1 AAA domain SbcCD_C PF13558.6 EPE25908.1 - 0.011 15.9 0.0 0.054 13.7 0.0 2.2 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit V-SNARE_C PF12352.8 EPE25908.1 - 0.022 15.1 6.2 5.8 7.3 0.0 4.7 4 0 0 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus Sugarporin_N PF11471.8 EPE25908.1 - 1.2 9.1 12.3 2.5 8.1 0.2 3.8 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension FPP PF05911.11 EPE25908.1 - 2.7 6.1 96.7 0.062 11.5 8.8 4.3 2 1 1 4 4 4 0 Filament-like plant protein, long coiled-coil DUF2838 PF10998.8 EPE25909.1 - 1.5e-44 150.8 19.7 3.3e-44 149.7 11.7 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2838) Apolipoprotein PF01442.18 EPE25909.1 - 1.3 8.9 8.0 0.58 10.0 4.2 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain WD40 PF00400.32 EPE25910.1 - 2.2e-17 63.1 15.4 0.0057 17.5 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE25910.1 - 4.6e-12 46.1 4.4 0.00026 21.2 0.3 4.2 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE25910.1 - 3.3e-06 27.1 0.0 0.025 14.4 0.1 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Glyco_hydro_32N PF00251.20 EPE25911.1 - 2.4e-81 273.7 5.0 3e-81 273.3 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EPE25911.1 - 9.2e-08 32.2 0.1 1.8e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Peptidase_M20 PF01546.28 EPE25912.1 - 1.3e-21 77.3 0.0 2.2e-21 76.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EPE25912.1 - 5.5e-10 39.1 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain CorA PF01544.18 EPE25913.1 - 0.0052 16.1 3.8 0.0063 15.9 2.9 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SPC25 PF06703.11 EPE25913.1 - 0.02 14.7 0.2 0.028 14.2 0.2 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) p450 PF00067.22 EPE25914.1 - 1.8e-30 106.2 0.0 4.5e-27 94.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 ABC2_membrane PF01061.24 EPE25915.1 - 1.1e-79 266.7 46.0 4.1e-42 144.0 23.2 3.0 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 EPE25915.1 - 1.5e-37 129.2 0.0 6.4e-18 65.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EPE25915.1 - 2.6e-35 120.2 9.4 4.8e-31 106.5 0.0 3.4 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EPE25915.1 - 1.2e-13 51.4 0.0 3e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EPE25915.1 - 2e-06 28.3 0.1 0.0049 17.3 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EPE25915.1 - 8.9e-06 25.4 0.3 0.00034 20.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EPE25915.1 - 9.5e-06 25.3 1.3 0.005 16.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EPE25915.1 - 1.2e-05 25.3 0.1 0.00039 20.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 EPE25915.1 - 3e-05 24.0 0.3 0.22 11.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPE25915.1 - 7.9e-05 22.2 0.0 0.81 9.1 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EPE25915.1 - 0.0016 18.8 0.4 0.097 12.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EPE25915.1 - 0.011 15.9 0.1 0.37 10.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EPE25915.1 - 0.011 16.2 0.0 0.28 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EPE25915.1 - 0.021 15.3 0.1 0.11 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EPE25915.1 - 0.037 13.8 0.3 0.73 9.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EPE25915.1 - 0.063 13.2 0.0 3.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 EPE25915.1 - 0.069 13.6 0.0 20 5.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ABC2_membrane_3 PF12698.7 EPE25915.1 - 0.08 12.0 43.0 0.18 10.9 17.4 2.8 2 1 0 2 2 2 0 ABC-2 family transporter protein AAA_24 PF13479.6 EPE25915.1 - 0.092 12.5 0.0 4.9 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EPE25915.1 - 0.12 12.5 0.0 21 5.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 EPE25915.1 - 0.12 12.3 0.9 5 7.0 0.1 2.6 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 EPE25915.1 - 0.13 12.0 0.1 2.2 8.0 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_28 PF13521.6 EPE25915.1 - 0.19 11.9 1.2 0.24 11.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 EPE25915.1 - 2.5 7.6 3.5 1.7 8.2 0.2 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Lactamase_B_2 PF12706.7 EPE25916.1 - 1.8e-24 86.4 0.0 3.1e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EPE25916.1 - 1.6e-08 34.7 0.0 3.1e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain EthD PF07110.11 EPE25917.1 - 3.8e-16 60.0 0.0 4.7e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EPE25917.1 - 0.0011 19.4 0.1 0.0014 19.0 0.1 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Ribosomal_L31 PF01197.18 EPE25918.1 - 0.065 13.5 0.1 0.19 12.0 0.0 1.8 2 1 0 2 2 2 0 Ribosomal protein L31 DUF4434 PF14488.6 EPE25919.1 - 0.11 12.6 0.2 1.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) PAS_6 PF08348.11 EPE25920.1 - 0.11 12.3 0.9 0.53 10.2 0.1 2.3 1 1 1 2 2 2 0 YheO-like PAS domain RR_TM4-6 PF06459.12 EPE25920.1 - 5.4 6.8 18.9 8.7 6.1 18.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NACHT PF05729.12 EPE25921.1 - 1.3e-12 48.0 0.0 3.2e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain zf-C2H2_4 PF13894.6 EPE25921.1 - 0.00022 21.8 29.7 0.015 16.0 0.7 5.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EPE25921.1 - 0.00082 19.7 2.0 0.00082 19.7 2.0 5.8 5 1 0 5 5 5 2 Zinc finger, C2H2 type AAA_22 PF13401.6 EPE25921.1 - 0.0036 17.6 0.1 0.015 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain zf-C2H2_jaz PF12171.8 EPE25921.1 - 0.0058 16.9 5.9 0.84 10.0 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding AAA PF00004.29 EPE25921.1 - 0.0061 17.0 0.9 0.078 13.4 0.9 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-C2H2_6 PF13912.6 EPE25921.1 - 0.047 13.7 10.1 0.56 10.3 0.1 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-BED PF02892.15 EPE25921.1 - 0.23 11.5 7.0 7.3 6.7 0.1 3.7 2 1 1 3 3 3 0 BED zinc finger SNF2_N PF00176.23 EPE25922.1 - 1.8e-67 227.5 0.1 2.5e-67 227.1 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE25922.1 - 4.7e-12 46.2 0.0 1.3e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE25922.1 - 5.5e-08 33.0 0.0 1.6e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 EPE25922.1 - 0.0023 17.8 8.3 0.0049 16.8 8.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EPE25922.1 - 0.064 13.1 9.9 0.7 9.8 9.6 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE25922.1 - 0.22 11.4 8.6 0.55 10.2 8.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 EPE25922.1 - 1.2 9.3 6.6 2.9 8.1 6.6 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_UBOX PF13445.6 EPE25922.1 - 2.4 8.3 5.2 7.1 6.8 5.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EPE25922.1 - 9.3 6.2 8.2 36 4.3 8.2 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PTPA PF03095.15 EPE25923.1 - 6.5e-113 377.1 0.0 7.8e-113 376.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RNase_PH PF01138.21 EPE25924.1 - 7.4e-12 45.9 0.2 1.1e-11 45.4 0.2 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EPE25924.1 - 0.037 14.1 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 NAD_kinase PF01513.21 EPE25925.1 - 1.1e-78 264.5 0.0 1.6e-78 263.9 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase PAN_1 PF00024.26 EPE25926.1 - 0.063 13.2 0.8 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 PAN domain Anp1 PF03452.14 EPE25928.1 - 2.2e-109 364.9 0.0 2.6e-109 364.7 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 EPE25928.1 - 0.025 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 ODV-E18 PF10717.9 EPE25928.1 - 0.032 14.1 0.1 0.064 13.1 0.1 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2615 PF11027.8 EPE25928.1 - 0.061 13.5 0.1 0.15 12.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) UQ_con PF00179.26 EPE25931.1 - 1.4e-25 89.5 0.0 1.8e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EPE25931.1 - 0.18 12.1 0.0 0.21 11.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain NUP PF06516.11 EPE25932.1 - 2.1e-122 408.3 0.0 2.5e-122 408.0 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Collagen PF01391.18 EPE25933.1 - 7.2e-20 70.5 88.3 8e-08 31.9 25.4 3.5 2 1 1 3 3 3 3 Collagen triple helix repeat (20 copies) WSC PF01822.19 EPE25933.1 - 2.5e-11 43.6 9.4 4.5e-11 42.8 9.4 1.4 1 0 0 1 1 1 1 WSC domain AbfB PF05270.13 EPE25933.1 - 0.16 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) domain CBM_4_9 PF02018.17 EPE25933.1 - 0.18 12.1 0.0 0.43 10.9 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain WSC PF01822.19 EPE25934.1 - 9.7e-17 60.9 8.4 1.4e-16 60.4 8.4 1.2 1 0 0 1 1 1 1 WSC domain Collagen PF01391.18 EPE25934.1 - 6.4e-07 29.0 26.3 1.2e-06 28.2 26.3 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF2841 PF11001.8 EPE25935.1 - 6.7e-43 145.7 1.2 1.1e-42 145.0 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) EIN3 PF04873.13 EPE25935.1 - 0.0076 15.6 0.3 0.013 14.8 0.3 1.4 1 0 0 1 1 1 1 Ethylene insensitive 3 TGase_elicitor PF16683.5 EPE25935.1 - 0.07 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase elicitor ABC_membrane PF00664.23 EPE25936.1 - 2e-68 231.0 23.1 3.1e-43 148.4 9.0 3.6 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EPE25936.1 - 1.5e-49 168.1 0.7 3.1e-30 105.5 0.1 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EPE25936.1 - 8.4e-09 35.2 4.6 0.015 14.8 0.0 4.4 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EPE25936.1 - 1.1e-05 25.5 0.6 0.12 12.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPE25936.1 - 0.00023 21.1 0.6 0.068 13.1 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 EPE25936.1 - 0.00065 20.1 1.7 0.08 13.3 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 EPE25936.1 - 0.00096 19.2 1.9 0.036 14.1 0.0 2.6 3 0 0 3 3 2 1 Dynamin family AAA_29 PF13555.6 EPE25936.1 - 0.0029 17.3 0.4 4.9 7.0 0.1 3.1 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 EPE25936.1 - 0.0037 17.4 0.1 1.2 9.2 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 EPE25936.1 - 0.0042 17.6 1.2 0.29 11.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EPE25936.1 - 0.005 16.6 0.7 0.13 12.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EPE25936.1 - 0.031 13.9 0.0 5.9 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain CDC45 PF02724.14 EPE25936.1 - 0.039 12.2 0.0 0.061 11.6 0.0 1.2 1 0 0 1 1 1 0 CDC45-like protein FtsK_SpoIIIE PF01580.18 EPE25936.1 - 0.11 11.9 0.1 10 5.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_21 PF13304.6 EPE25936.1 - 0.2 11.5 0.9 6 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EPE25936.1 - 0.2 11.9 0.7 29 4.9 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 EPE25936.1 - 0.37 10.4 1.5 2.4 7.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 EPE25936.1 - 0.37 11.0 2.2 24 5.1 0.0 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EPE25936.1 - 0.59 10.0 2.5 1.6 8.6 0.1 2.7 3 0 0 3 3 3 0 NACHT domain AAA_15 PF13175.6 EPE25936.1 - 0.69 9.6 5.1 1.2 8.8 0.1 2.9 3 0 0 3 3 3 0 AAA ATPase domain HLH PF00010.26 EPE25937.1 - 1.8e-12 47.0 0.3 3.6e-12 46.0 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GIT1_C PF12205.8 EPE25937.1 - 0.026 14.6 1.3 0.2 11.8 1.3 2.2 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term CLTH PF10607.9 EPE25938.1 - 8.3e-34 116.6 0.1 1.5e-33 115.8 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EPE25938.1 - 0.00092 19.1 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 LisH Nic96 PF04097.14 EPE25938.1 - 0.011 14.2 0.6 0.052 12.0 0.0 2.0 2 0 0 2 2 2 0 Nup93/Nic96 Peptidase_M28 PF04389.17 EPE25941.1 - 6.3e-37 127.2 0.0 1.1e-36 126.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EPE25941.1 - 1.1e-06 28.5 0.0 3.9e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Acetyltransf_1 PF00583.25 EPE25942.1 - 1.3e-12 47.9 0.0 2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE25942.1 - 2.9e-10 40.4 0.0 6.3e-10 39.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPE25942.1 - 9.2e-10 38.5 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE25942.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 EPE25942.1 - 0.029 14.5 0.0 0.075 13.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF108 PF01958.18 EPE25942.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF108 AMP-binding PF00501.28 EPE25943.1 - 2.3e-65 220.9 0.0 4e-65 220.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EPE25943.1 - 6.6e-63 213.0 0.0 1.3e-34 119.7 0.0 3.2 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.25 EPE25943.1 - 1.2e-26 92.9 0.2 5.5e-13 49.1 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site FlaC_arch PF05377.11 EPE25944.1 - 0.068 13.6 0.5 5.9 7.4 0.8 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 EPE25944.1 - 0.1 11.4 13.2 0.19 10.6 13.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_35 PF14516.6 EPE25944.1 - 0.17 10.7 2.6 0.26 10.1 2.6 1.2 1 0 0 1 1 1 0 AAA-like domain LMBR1 PF04791.16 EPE25944.1 - 0.39 9.6 0.9 0.59 9.0 0.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Golgin_A5 PF09787.9 EPE25944.1 - 0.59 9.6 11.9 1.2 8.6 11.9 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 ProSAAS PF07259.12 EPE25944.1 - 2.5 8.1 6.0 21 5.0 0.1 2.6 2 0 0 2 2 2 0 ProSAAS precursor Latarcin PF10279.9 EPE25944.1 - 3.3 8.2 7.4 7.2 7.1 7.4 1.5 1 0 0 1 1 1 0 Latarcin precursor NmrA PF05368.13 EPE25945.1 - 1.9e-44 151.9 0.1 2.3e-44 151.7 0.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE25945.1 - 2.5e-13 50.3 0.0 3.3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE25945.1 - 0.00016 21.2 0.2 0.00024 20.7 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EPE25945.1 - 0.00097 18.6 0.4 0.0014 18.1 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 EPE25945.1 - 0.0024 16.9 0.0 0.0031 16.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 EPE25945.1 - 0.04 14.0 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.18 EPE25946.1 - 7.9e-17 61.2 0.1 1.3e-16 60.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE25946.1 - 6.8e-08 32.5 11.6 1.3e-07 31.6 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ASD1 PF08688.10 EPE25946.1 - 0.018 15.5 0.1 0.037 14.4 0.1 1.5 1 0 0 1 1 1 0 Apx/Shroom domain ASD1 Ytp1 PF10355.9 EPE25947.1 - 9.6e-71 238.2 18.0 9.6e-71 238.2 18.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EPE25947.1 - 3.7e-32 110.2 4.0 3.7e-32 110.2 4.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Ank_2 PF12796.7 EPE25948.1 - 5.7e-39 132.6 0.0 3.6e-11 43.5 0.1 8.4 7 1 0 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE25948.1 - 2.5e-27 94.9 0.0 8.9e-05 23.0 0.0 10.2 9 2 1 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE25948.1 - 1.5e-26 89.5 6.6 2.7e-05 24.2 0.1 11.0 12 0 0 12 12 12 5 Ankyrin repeat Ank PF00023.30 EPE25948.1 - 9.3e-25 85.9 5.1 1.3e-05 25.4 0.2 9.7 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 EPE25948.1 - 2.2e-21 75.6 1.8 0.00084 19.6 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeats (many copies) ABM PF03992.16 EPE25949.1 - 0.0041 17.2 0.0 0.47 10.6 0.0 2.5 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF4553 PF15090.6 EPE25951.1 - 4.1 6.3 30.2 5.2 5.9 30.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) Whi5 PF08528.11 EPE25952.1 - 3.8e-12 45.6 0.0 6.6e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Whi5 like NAD_binding_11 PF14833.6 EPE25952.1 - 0.3 11.3 2.1 0.51 10.6 0.2 2.3 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase V-SNARE_C PF12352.8 EPE25955.1 - 4.4e-13 49.3 1.2 7e-13 48.7 0.1 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EPE25955.1 - 0.0001 22.1 0.4 0.0025 17.7 0.0 2.4 2 1 0 2 2 2 1 Sec20 V-SNARE PF05008.15 EPE25955.1 - 0.017 15.5 0.4 0.047 14.1 0.2 1.9 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus TPR_MLP1_2 PF07926.12 EPE25955.1 - 0.12 12.4 5.2 0.18 11.9 1.8 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 EPE25955.1 - 0.2 11.0 3.3 0.74 9.1 1.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Sec2p PF06428.11 EPE25955.1 - 0.78 9.8 4.8 6.8 6.7 1.0 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p KxDL PF10241.9 EPE25955.1 - 1.1 9.6 5.7 14 6.0 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein Arb1 PF09692.10 EPE25956.1 - 3.9e-122 408.3 0.2 1.5e-121 406.4 0.2 1.7 1 1 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF188 PF02639.14 EPE25956.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 IPK PF03770.16 EPE25957.1 - 5.1e-50 170.1 0.0 6.5e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase CLP1_P PF16575.5 EPE25958.1 - 8.4e-37 126.8 0.0 1.7e-36 125.8 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 EPE25958.1 - 2.8e-36 123.6 0.0 5.6e-36 122.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 EPE25958.1 - 8.3e-32 110.0 0.0 1.3e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MMR_HSR1 PF01926.23 EPE25958.1 - 0.0003 20.8 0.1 0.0045 17.0 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EPE25958.1 - 0.00055 19.7 0.0 0.43 10.3 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 EPE25958.1 - 0.0041 16.8 0.0 0.02 14.6 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EPE25958.1 - 0.0074 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 EPE25958.1 - 0.01 15.7 0.0 0.083 12.7 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EPE25958.1 - 0.01 16.4 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 EPE25958.1 - 0.014 15.5 0.0 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_21 PF13304.6 EPE25958.1 - 0.016 15.1 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system TniB PF05621.11 EPE25958.1 - 0.016 14.6 0.0 0.058 12.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_35 PF14516.6 EPE25958.1 - 0.045 12.6 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_15 PF13175.6 EPE25958.1 - 0.05 13.3 0.0 0.077 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 EPE25958.1 - 0.095 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EPE25958.1 - 0.1 13.0 0.0 0.29 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 EPE25958.1 - 0.14 11.6 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMS1_N PF10433.9 EPE25960.1 - 7.4e-124 414.0 0.1 2e-123 412.6 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EPE25960.1 - 3.9e-61 207.2 0.2 2.9e-60 204.3 0.0 2.5 3 0 0 3 3 3 1 CPSF A subunit region PQQ_2 PF13360.6 EPE25960.1 - 0.0088 15.6 0.2 9.8 5.7 0.0 3.3 3 0 0 3 3 3 2 PQQ-like domain Sin_N PF04801.13 EPE25961.1 - 2.5e-25 89.6 0.6 1e-24 87.6 0.5 1.8 1 1 0 1 1 1 1 Sin-like protein conserved region Pmp3 PF01679.17 EPE25962.1 - 3e-20 72.2 8.6 3.9e-20 71.8 8.6 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator UbiA PF01040.18 EPE25962.1 - 0.053 12.8 0.0 0.073 12.4 0.0 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family TMEM52 PF14979.6 EPE25962.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane 52 NAD_binding_2 PF03446.15 EPE25963.1 - 2.9e-38 131.5 0.1 4.3e-38 131.0 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EPE25963.1 - 6.1e-27 94.3 0.0 1.2e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.15 EPE25963.1 - 1.6e-06 27.3 0.0 2.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 EPE25963.1 - 4e-05 24.1 0.0 8.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 EPE25963.1 - 0.0033 18.3 0.0 0.0086 16.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ATP-synt_C PF00137.21 EPE25964.1 - 1.9e-27 95.3 28.7 7.3e-16 58.3 12.5 2.4 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 EPE25964.1 - 0.27 10.6 2.2 0.85 8.9 0.0 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 TFIIA_gamma_N PF02268.16 EPE25965.1 - 1.6e-25 88.9 0.2 2.3e-25 88.3 0.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 EPE25965.1 - 4.1e-24 84.5 0.8 7e-24 83.7 0.8 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit EamA PF00892.20 EPE25966.1 - 9e-05 22.7 18.6 0.00055 20.1 18.6 1.9 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 EPE25966.1 - 0.47 10.5 4.7 0.68 10.0 4.5 1.4 1 1 0 1 1 1 0 Putative transmembrane family 234 KilA-N PF04383.13 EPE25968.1 - 0.0011 18.7 0.3 0.0077 16.1 0.0 2.4 2 1 0 2 2 2 1 KilA-N domain Hamartin PF04388.12 EPE25968.1 - 0.025 13.3 10.6 0.03 13.0 10.6 1.0 1 0 0 1 1 1 0 Hamartin protein Alk_phosphatase PF00245.20 EPE25972.1 - 4.7e-108 361.8 0.0 6.3e-108 361.4 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EPE25972.1 - 0.00019 20.9 0.0 0.00038 19.9 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Ribosomal_L34e PF01199.18 EPE25973.1 - 2.4e-42 143.2 1.5 3.5e-42 142.6 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 EPE25973.1 - 1.7 8.6 5.1 4.8 7.2 0.1 2.6 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain zinc_ribbon_5 PF13719.6 EPE25973.1 - 3.6 7.4 6.3 1.6 8.5 0.8 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Gaa1 PF04114.14 EPE25974.1 - 5.5e-173 576.5 5.2 6.6e-173 576.3 5.2 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Rhomboid PF01694.22 EPE25975.1 - 8.3e-14 51.8 7.2 8.3e-14 51.8 7.2 1.6 2 0 0 2 2 2 1 Rhomboid family DUF3487 PF11990.8 EPE25975.1 - 0.26 11.2 0.1 0.26 11.2 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) DUF2070 PF09843.9 EPE25975.1 - 0.39 9.0 9.6 0.45 8.8 9.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Aconitase PF00330.20 EPE25976.1 - 2e-141 472.1 0.0 2.7e-141 471.7 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EPE25976.1 - 9.4e-45 152.1 0.0 1.8e-44 151.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 EPE25976.1 - 0.11 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) zf-C2H2_jaz PF12171.8 EPE25977.1 - 1.1e-09 38.3 5.4 4.7e-09 36.3 1.1 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding GH-E PF14410.6 EPE25977.1 - 0.0096 16.3 0.0 0.027 14.8 0.0 1.7 2 0 0 2 2 2 1 HNH/ENDO VII superfamily nuclease with conserved GHE residues zf-C2H2_4 PF13894.6 EPE25977.1 - 0.022 15.6 2.9 0.065 14.1 0.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger L31 PF09784.9 EPE25977.1 - 0.077 13.4 0.7 0.13 12.7 0.6 1.5 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 zf-met PF12874.7 EPE25977.1 - 1.1 9.7 5.3 2.6 8.6 1.2 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EPE25977.1 - 7.5 6.7 7.9 0.29 11.2 1.4 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger DASH_Dam1 PF08653.10 EPE25978.1 - 5e-28 96.7 3.1 6.8e-28 96.3 3.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.20 EPE25979.1 - 4.1e-44 150.1 0.0 8.4e-44 149.1 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EPE25979.1 - 1.6e-15 57.0 0.3 8.9e-15 54.6 0.0 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EPE25979.1 - 3e-06 27.4 0.0 5.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HIT PF01230.23 EPE25980.1 - 1.3e-24 86.8 0.3 1.8e-24 86.3 0.3 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EPE25980.1 - 3.2e-15 56.6 0.1 5e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EPE25980.1 - 5.1e-07 29.6 0.5 7.1e-07 29.1 0.5 1.3 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Ssl1 PF04056.14 EPE25980.1 - 0.077 12.8 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Ssl1-like Mog1 PF04603.12 EPE25981.1 - 8e-41 139.6 0.0 9.6e-41 139.4 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Gemini_AL1 PF00799.20 EPE25981.1 - 0.15 12.4 0.0 7.8 6.9 0.0 2.4 2 1 0 2 2 2 0 Geminivirus Rep catalytic domain Myb_DNA-bind_6 PF13921.6 EPE25982.1 - 4.9e-12 45.9 0.5 9.4e-10 38.6 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EPE25982.1 - 9.8e-12 44.9 0.5 8.2e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.12 EPE25982.1 - 0.033 13.9 0.0 0.086 12.5 0.0 1.6 2 0 0 2 2 2 0 Sigma-70, region 4 DUF5053 PF16476.5 EPE25982.1 - 0.21 11.3 0.1 0.56 9.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) SUIM_assoc PF16619.5 EPE25982.1 - 2.4 8.3 9.7 1.1 9.3 6.3 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PROCN PF08083.11 EPE25983.1 - 2.9e-235 780.5 8.4 2.9e-235 780.5 8.4 2.1 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EPE25983.1 - 1.8e-126 420.4 1.4 3.6e-126 419.4 1.4 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EPE25983.1 - 1.8e-89 297.7 2.2 6.6e-89 295.9 2.2 2.1 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EPE25983.1 - 1.5e-80 268.5 1.6 1.5e-80 268.5 1.6 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EPE25983.1 - 2.3e-69 231.6 0.1 4.8e-69 230.6 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EPE25983.1 - 5.9e-48 161.2 0.3 1.5e-47 159.8 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EPE25983.1 - 6.6e-47 158.5 0.2 2.5e-46 156.6 0.0 2.1 2 0 0 2 2 2 1 PROCT (NUC072) domain BLACT_WH PF17778.1 EPE25984.1 - 5.3e-17 61.5 0.1 1.2e-16 60.3 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 EPE25984.1 - 3.4e-16 59.8 2.7 5.1e-14 52.7 2.7 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EPE25984.1 - 0.00078 19.0 0.1 0.0013 18.3 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Ytp1 PF10355.9 EPE25985.1 - 1.5e-112 375.4 11.3 2.4e-112 374.7 11.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EPE25985.1 - 1.4e-30 105.1 6.7 1.4e-30 105.1 6.7 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) DUF4133 PF13571.6 EPE25985.1 - 1.2 9.5 8.3 0.14 12.5 0.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) COX5B PF01215.19 EPE25986.1 - 3.9e-56 188.3 0.0 5.7e-56 187.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.19 EPE25986.1 - 0.036 13.8 1.2 9 6.2 0.0 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger ABC_membrane PF00664.23 EPE25987.1 - 1.2e-34 120.2 9.3 1.2e-34 120.2 9.3 2.3 3 0 0 3 3 3 1 ABC transporter transmembrane region ABC_tran PF00005.27 EPE25987.1 - 3.8e-33 114.9 0.0 8.7e-33 113.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EPE25987.1 - 3.8e-07 29.8 0.0 1.6e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EPE25987.1 - 0.005 16.8 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 EPE25987.1 - 0.0095 16.2 0.5 0.18 12.0 0.5 2.8 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 EPE25987.1 - 0.02 15.3 0.3 0.082 13.3 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EPE25987.1 - 0.033 14.5 0.3 0.27 11.5 0.3 2.3 1 1 0 1 1 1 0 AAA domain OTT_1508_deam PF14441.6 EPE25988.1 - 8.9e-17 60.9 1.7 8.9e-17 60.9 1.7 2.1 2 0 0 2 2 2 1 OTT_1508-like deaminase DUF410 PF04190.13 EPE25988.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF410) Aminotran_1_2 PF00155.21 EPE25989.1 - 4e-37 128.2 0.0 5.3e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EPE25989.1 - 0.00025 19.7 0.0 0.00054 18.6 0.0 1.4 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Glucan_synthase PF02364.15 EPE25990.1 - 0 1385.8 0.0 0 1385.3 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EPE25990.1 - 1.2e-42 145.3 1.3 3.6e-42 143.7 1.3 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 XhlA PF10779.9 EPE25990.1 - 0.37 11.0 1.5 1.1 9.6 1.5 1.8 1 0 0 1 1 1 0 Haemolysin XhlA Glyco_hydro_72 PF03198.14 EPE25991.1 - 6.2e-129 429.8 1.3 8.5e-129 429.3 1.3 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EPE25991.1 - 2.6e-24 85.7 8.7 3e-24 85.5 6.9 2.1 2 0 0 2 2 2 1 X8 domain RasGAP PF00616.19 EPE25992.1 - 1.8e-59 200.9 2.1 3.9e-59 199.9 0.0 2.5 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase SprT-like PF10263.9 EPE25992.1 - 1.3e-37 128.1 0.9 2.5e-37 127.2 0.9 1.5 1 0 0 1 1 1 1 SprT-like family RasGAP_C PF03836.15 EPE25992.1 - 5.4e-29 101.1 3.5 5.4e-29 101.1 3.5 2.4 2 0 0 2 2 2 1 RasGAP C-terminus Zn_ribbon_SprT PF17283.2 EPE25992.1 - 9.7e-10 38.2 3.0 2.1e-09 37.1 3.0 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain HMG_box PF00505.19 EPE25992.1 - 0.046 14.1 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 HMG (high mobility group) box Zn-ribbon_8 PF09723.10 EPE25992.1 - 0.053 13.6 0.3 0.11 12.6 0.3 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Imm59 PF15597.6 EPE25992.1 - 0.23 12.0 0.8 46 4.6 0.0 3.0 3 0 0 3 3 3 0 Immunity protein 59 AA_permease PF00324.21 EPE25993.1 - 9.2e-127 423.5 37.7 1.1e-126 423.3 37.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE25993.1 - 1.2e-28 100.2 42.8 1.4e-28 99.9 42.8 1.0 1 0 0 1 1 1 1 Amino acid permease CYSTM PF12734.7 EPE25995.1 - 0.00023 21.4 3.4 0.00023 21.4 3.4 3.1 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 EPE25995.1 - 6.8 7.3 10.2 8.6 7.0 10.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HET PF06985.11 EPE25996.1 - 2e-11 44.4 7.0 2.6e-09 37.6 0.6 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) zf-C2H2 PF00096.26 EPE25997.1 - 3e-09 36.8 21.0 0.011 16.2 0.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE25997.1 - 6.7e-08 32.7 17.8 0.041 14.7 5.4 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE25997.1 - 0.049 13.9 11.5 0.74 10.2 2.6 3.7 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EPE25997.1 - 0.077 13.5 15.5 4.3 7.9 1.0 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2HC_2 PF13913.6 EPE25997.1 - 0.32 11.0 8.1 0.2 11.6 0.6 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 EPE25997.1 - 1.9 8.9 6.7 1.6 9.1 3.2 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ank_2 PF12796.7 EPE25998.1 - 1.1e-33 115.6 7.0 4.6e-12 46.3 0.4 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE25998.1 - 5.3e-22 77.9 1.5 7.5e-11 42.3 0.1 5.9 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 EPE25998.1 - 3.4e-17 62.0 1.9 0.00015 22.1 0.2 5.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 EPE25998.1 - 8.7e-16 56.4 1.5 0.00064 20.0 0.0 6.3 5 1 2 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EPE25998.1 - 2.8e-13 49.8 1.3 1.9e-05 24.9 0.1 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ferric_reduct PF01794.19 EPE25999.1 - 1.3e-23 83.5 11.8 1.3e-23 83.5 11.8 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EPE25999.1 - 2.1e-19 70.1 0.1 4.1e-17 62.7 0.1 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EPE25999.1 - 3.8e-10 39.8 0.0 2.8e-09 37.0 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EPE25999.1 - 0.041 14.5 0.0 0.14 12.8 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF1690 PF07956.11 EPE26000.1 - 6.3e-44 149.8 2.1 7.3e-44 149.6 2.1 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Rootletin PF15035.6 EPE26000.1 - 0.058 13.4 4.6 0.18 11.8 4.6 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF2407_C PF13373.6 EPE26000.1 - 0.14 12.3 0.5 0.23 11.6 0.3 1.5 1 1 0 1 1 1 0 DUF2407 C-terminal domain ParE-like_toxin PF15781.5 EPE26000.1 - 0.32 11.0 1.0 0.62 10.1 0.0 1.9 2 0 0 2 2 2 0 ParE-like toxin of type II bacterial toxin-antitoxin system Med9 PF07544.13 EPE26000.1 - 0.43 10.7 4.3 0.54 10.4 0.1 2.6 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TYW3 PF02676.14 EPE26001.1 - 1.1e-69 234.1 0.0 1.3e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 ARPC4 PF05856.12 EPE26003.1 - 2.6e-80 267.9 4.3 3e-80 267.7 4.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) ARID PF01388.21 EPE26005.1 - 7.7e-20 71.4 0.1 7.7e-20 71.4 0.1 3.2 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 EPE26005.1 - 0.0031 16.8 0.1 0.0031 16.8 0.1 2.3 2 0 0 2 2 2 1 SWI/SNF-like complex subunit BAF250/Osa Img2 PF05046.14 EPE26006.1 - 4.1e-20 71.9 0.3 5.5e-20 71.4 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Propep_M14 PF02244.16 EPE26006.1 - 0.029 14.7 0.4 0.5 10.8 0.0 2.6 1 1 1 2 2 2 0 Carboxypeptidase activation peptide eIF3_N PF09440.10 EPE26007.1 - 1.8e-45 154.7 0.7 5.3e-45 153.1 0.7 1.8 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EPE26007.1 - 1.4e-15 57.6 0.0 1.9e-14 54.0 0.0 2.4 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 EPE26007.1 - 0.044 13.5 0.5 0.14 11.8 0.0 2.0 2 1 1 3 3 3 0 26S proteasome subunit RPN7 EVE PF01878.18 EPE26008.1 - 3.5e-47 160.0 0.1 3.5e-47 160.0 0.1 1.5 2 0 0 2 2 2 1 EVE domain FAM220 PF15487.6 EPE26008.1 - 3.6 7.2 8.7 5.8 6.5 8.7 1.3 1 0 0 1 1 1 0 FAM220 family Acyl_transf_3 PF01757.22 EPE26014.1 - 9e-29 100.6 26.0 1.1e-28 100.2 26.0 1.1 1 0 0 1 1 1 1 Acyltransferase family GFA PF04828.14 EPE26015.1 - 1.8e-21 76.3 0.0 2.4e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.16 EPE26017.1 - 1.5e-39 135.9 36.8 4.6e-39 134.3 30.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPE26017.1 - 5.5e-09 35.0 1.6 8.3e-09 34.4 1.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPE26017.1 - 8.7e-09 34.7 8.1 8.7e-09 34.7 8.1 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter Asp-Al_Ex PF06826.12 EPE26017.1 - 0.0041 16.9 4.1 0.0041 16.9 4.1 2.1 2 0 0 2 2 2 1 Predicted Permease Membrane Region eIF2A PF08662.11 EPE26018.1 - 1e-78 263.7 0.0 2.4e-77 259.2 0.0 2.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EPE26018.1 - 0.0044 17.8 0.5 3.2 8.8 0.0 4.5 3 2 2 5 5 5 1 WD domain, G-beta repeat PD40 PF07676.12 EPE26018.1 - 0.19 11.7 7.4 27 4.9 0.0 5.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat TFIIA PF03153.13 EPE26018.1 - 1.1 9.1 18.7 1.8 8.5 18.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IHABP4_N PF16174.5 EPE26018.1 - 7.3 7.2 27.9 12 6.4 27.9 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal ANAPC1 PF12859.7 EPE26019.1 - 7.3e-42 143.0 0.1 3.2e-41 140.9 0.1 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EPE26019.1 - 0.0021 18.4 1.4 15 6.3 0.0 4.4 4 0 0 4 4 4 2 Proteasome/cyclosome repeat CsbD PF05532.12 EPE26020.1 - 0.0044 16.9 16.7 0.0044 16.9 16.7 3.8 2 1 1 3 3 3 1 CsbD-like kleA_kleC PF17383.2 EPE26020.1 - 0.078 13.3 0.9 0.13 12.6 0.9 1.4 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A YtxH PF12732.7 EPE26020.1 - 2.7 8.6 14.4 90 3.7 14.4 2.2 1 1 0 1 1 1 0 YtxH-like protein LEA_4 PF02987.16 EPE26020.1 - 9.9 6.3 22.0 8.1 6.6 16.7 2.9 2 1 0 2 2 2 0 Late embryogenesis abundant protein Sec7 PF01369.20 EPE26021.1 - 3.4e-29 101.8 0.1 7.6e-29 100.7 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EPE26021.1 - 6e-19 68.6 0.0 1.2e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RR_TM4-6 PF06459.12 EPE26022.1 - 0.49 10.2 9.7 6.7 6.5 12.0 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 EPE26022.1 - 2.4 8.6 10.6 4.3 7.7 10.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF913 PF06025.12 EPE26022.1 - 5 6.0 5.5 6.7 5.6 5.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 EPE26022.1 - 5 5.8 9.5 6.3 5.5 9.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SesA PF17107.5 EPE26023.1 - 7.9e-05 22.8 0.0 9.3e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases GAS PF13851.6 EPE26023.1 - 0.00067 19.1 0.1 0.00071 19.0 0.1 1.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Mad3_BUB1_I PF08311.12 EPE26023.1 - 0.0042 17.1 0.3 0.0044 17.0 0.3 1.1 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Ank_5 PF13857.6 EPE26026.1 - 6.4e-12 45.5 0.4 4.5e-08 33.2 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE26026.1 - 1.9e-10 41.2 0.0 2.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE26026.1 - 3.8e-09 36.9 0.3 1.3e-06 28.9 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EPE26026.1 - 2.1e-08 34.2 0.2 2.4e-05 24.6 0.4 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EPE26026.1 - 1.3e-06 28.2 0.0 0.0021 18.4 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeat ECH_1 PF00378.20 EPE26027.1 - 9e-47 159.5 0.0 4.3e-41 140.9 0.0 2.9 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPE26027.1 - 4.6e-27 95.4 0.5 2.1e-24 86.7 0.1 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase HET PF06985.11 EPE26028.1 - 2.2e-35 122.1 3.7 4.1e-35 121.3 3.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RTA1 PF04479.13 EPE26029.1 - 9.6e-41 139.7 5.6 1.3e-40 139.2 5.6 1.2 1 0 0 1 1 1 1 RTA1 like protein Sec3_C PF09763.9 EPE26030.1 - 0.57 8.5 3.4 1.4 7.2 3.5 1.5 2 0 0 2 2 2 0 Exocyst complex component Sec3 Presenilin PF01080.17 EPE26030.1 - 3.1 6.5 4.2 4.6 5.9 4.2 1.2 1 0 0 1 1 1 0 Presenilin SHMT PF00464.19 EPE26031.1 - 1.1e-206 686.2 0.0 1.3e-206 685.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EPE26031.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase HAD_2 PF13419.6 EPE26032.1 - 4.3e-12 46.5 0.0 9.2e-12 45.4 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPE26032.1 - 5.3e-06 26.9 0.0 8.1e-05 23.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPE26032.1 - 7.7e-06 25.9 0.1 1.3e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like HNH PF01844.23 EPE26033.1 - 0.0036 17.4 2.0 0.0097 16.1 2.0 1.7 1 0 0 1 1 1 1 HNH endonuclease CLP1_P PF16575.5 EPE26035.1 - 3.6e-31 108.4 0.0 5.8e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 EPE26035.1 - 0.041 14.0 0.1 0.091 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EPE26035.1 - 0.073 13.6 0.0 0.25 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EPE26035.1 - 0.26 11.7 0.1 0.26 11.7 0.1 2.1 3 0 0 3 3 3 0 RNA helicase RNA_polI_A34 PF08208.11 EPE26036.1 - 8.7e-47 159.9 6.7 8.7e-47 159.9 6.7 3.1 2 1 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF5549 PF17703.1 EPE26036.1 - 0.02 14.6 0.5 0.02 14.6 0.5 2.6 2 2 2 4 4 4 0 Family of unknown function (DUF5549) PAF-AH_p_II PF03403.13 EPE26037.1 - 6.7e-19 67.7 0.0 1.8e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EPE26037.1 - 4.7e-06 25.7 0.0 1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EPE26037.1 - 0.0022 17.1 0.3 1.2 8.1 0.1 2.3 2 0 0 2 2 2 2 Chlorophyllase Abhydrolase_6 PF12697.7 EPE26037.1 - 0.0026 18.4 0.5 0.0049 17.5 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE26037.1 - 0.011 15.1 0.2 0.72 9.1 0.3 2.4 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE26037.1 - 0.015 15.0 0.1 0.07 12.8 0.1 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold LIP PF03583.14 EPE26037.1 - 0.031 13.6 0.1 0.043 13.1 0.1 1.2 1 0 0 1 1 1 0 Secretory lipase Peptidase_S9 PF00326.21 EPE26037.1 - 0.05 13.1 0.6 0.11 12.0 0.6 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family O-FucT PF10250.9 EPE26038.1 - 2.7e-19 70.1 0.0 9.5e-19 68.3 0.0 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PUA_2 PF14306.6 EPE26038.1 - 0.1 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 PUA-like domain AAA PF00004.29 EPE26039.1 - 1.9e-45 154.5 0.4 5.6e-45 153.0 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EPE26039.1 - 1.7e-09 37.5 0.1 1.1e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EPE26039.1 - 8.8e-09 35.5 0.2 3.1e-08 33.7 0.1 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EPE26039.1 - 6.3e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EPE26039.1 - 1.8e-07 31.7 0.5 3.5e-05 24.3 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EPE26039.1 - 5.5e-06 25.7 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EPE26039.1 - 4.5e-05 23.7 1.4 0.0081 16.4 0.1 2.7 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EPE26039.1 - 0.00032 20.5 0.0 0.00091 19.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 EPE26039.1 - 0.00042 20.0 0.1 0.00099 18.9 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 EPE26039.1 - 0.00047 20.7 0.0 0.0014 19.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EPE26039.1 - 0.00058 20.2 0.0 0.0017 18.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 EPE26039.1 - 0.00097 19.4 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EPE26039.1 - 0.0012 18.4 0.0 0.0096 15.4 0.1 2.2 2 1 0 2 2 2 1 P-loop containing dynein motor region TIP49 PF06068.13 EPE26039.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 EPE26039.1 - 0.0015 18.5 0.0 0.022 14.7 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EPE26039.1 - 0.0016 18.5 0.1 0.0069 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EPE26039.1 - 0.0031 17.4 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 EPE26039.1 - 0.0054 16.5 0.1 0.013 15.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EPE26039.1 - 0.0065 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EPE26039.1 - 0.0083 15.5 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EPE26039.1 - 0.0086 16.0 0.1 0.11 12.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain TniB PF05621.11 EPE26039.1 - 0.0088 15.5 0.0 0.54 9.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AAA_33 PF13671.6 EPE26039.1 - 0.0088 16.2 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EPE26039.1 - 0.014 15.1 0.1 0.044 13.5 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 EPE26039.1 - 0.019 14.7 0.2 0.046 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EPE26039.1 - 0.032 13.6 1.2 0.56 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC ATPase_2 PF01637.18 EPE26039.1 - 0.035 14.0 1.1 0.22 11.4 0.1 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EPE26039.1 - 0.045 13.5 0.1 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 EPE26039.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 EPE26039.1 - 0.078 12.7 0.2 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.14 EPE26039.1 - 0.087 11.3 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AAA_25 PF13481.6 EPE26039.1 - 0.11 12.1 1.3 0.26 10.9 0.1 2.1 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 EPE26039.1 - 0.13 12.6 0.1 0.41 11.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EPE26039.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 EPE26039.1 - 0.21 10.7 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mis14 PF08641.12 EPE26041.1 - 2.6e-15 56.9 0.8 2.6e-15 56.9 0.8 1.7 1 1 1 2 2 2 1 Kinetochore protein Mis14 like SPESP1 PF15754.5 EPE26041.1 - 0.021 14.0 0.2 0.027 13.7 0.2 1.3 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 DNTTIP1_dimer PF18192.1 EPE26041.1 - 0.074 13.4 0.5 2.4 8.5 0.0 2.5 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain Pox_polyA_pol_N PF12630.7 EPE26041.1 - 0.15 12.5 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Cdh1_DBD_1 PF18196.1 EPE26041.1 - 0.28 11.5 4.0 1.9 8.8 4.3 2.0 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 tRNA_m1G_MT PF01746.21 EPE26042.1 - 1.2e-27 96.9 0.0 1.2e-22 80.6 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase ORC_WH_C PF18137.1 EPE26042.1 - 3.6 7.6 7.6 4.6 7.3 0.1 2.3 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal MutS_V PF00488.21 EPE26043.1 - 1.8e-82 276.0 0.1 3e-82 275.2 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EPE26043.1 - 5.6e-37 127.8 0.8 1.2e-36 126.8 0.6 1.7 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EPE26043.1 - 9.3e-20 71.3 0.0 3.5e-19 69.5 0.0 2.1 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.20 EPE26043.1 - 1.3e-19 70.5 0.0 6.9e-19 68.2 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 EPE26043.1 - 6.8e-17 61.6 0.5 1.9e-16 60.2 0.5 1.8 1 0 0 1 1 1 1 MutS family domain IV SUR7 PF06687.12 EPE26043.1 - 0.0081 15.8 0.0 0.022 14.4 0.0 1.7 2 0 0 2 2 2 1 SUR7/PalI family AAA_27 PF13514.6 EPE26043.1 - 0.047 13.3 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EPE26043.1 - 0.054 13.4 0.1 0.27 11.1 0.0 2.2 2 1 0 2 2 2 0 Rad17 P-loop domain ArdA PF07275.11 EPE26043.1 - 0.31 11.6 1.6 0.59 10.7 0.2 2.2 2 0 0 2 2 2 0 Antirestriction protein (ArdA) Folliculin PF11704.8 EPE26044.1 - 2.2e-60 203.7 0.1 8.8e-60 201.8 0.0 2.0 3 0 0 3 3 3 1 Vesicle coat protein involved in Golgi to plasma membrane transport DEAD PF00270.29 EPE26045.1 - 7.8e-43 146.3 0.0 1.1e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE26045.1 - 6.2e-28 97.4 0.6 1.2e-26 93.2 0.5 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE26045.1 - 0.00017 21.6 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit QSregVF PF13652.6 EPE26045.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor CMS1 PF14617.6 EPE26045.1 - 0.15 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DNA_primase_S PF01896.19 EPE26046.1 - 8.6e-64 214.8 0.2 1.2e-63 214.4 0.2 1.2 1 0 0 1 1 1 1 DNA primase small subunit DNA_pol_A_exo1 PF01612.20 EPE26047.1 - 3.2e-43 147.5 0.1 6.8e-43 146.4 0.1 1.6 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EPE26047.1 - 1e-29 103.1 0.8 7.9e-29 100.2 0.6 2.5 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 EPE26047.1 - 4.3e-11 42.6 0.0 9.7e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 HRDC domain BNIP2 PF12496.8 EPE26047.1 - 0.47 10.9 10.6 3.5 8.1 2.3 3.1 3 0 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Peptidase_S49_N PF08496.10 EPE26047.1 - 6.1 6.9 6.2 14 5.7 6.2 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal UPF0203 PF05254.12 EPE26048.1 - 2.2e-27 95.1 3.1 3.1e-27 94.6 3.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 EPE26048.1 - 0.00049 20.4 0.5 0.00049 20.4 0.5 1.8 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 EPE26048.1 - 0.0032 17.5 4.1 0.072 13.1 0.1 2.4 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 EPE26048.1 - 0.03 14.5 1.2 0.03 14.5 1.2 1.9 1 1 2 3 3 3 0 Ubiquinol-cytochrome C reductase hinge protein DUF3128 PF11326.8 EPE26048.1 - 0.13 12.6 4.5 0.35 11.3 4.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) NDUF_B7 PF05676.13 EPE26048.1 - 0.22 11.2 4.9 1.4 8.7 0.3 2.3 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF5339 PF17274.2 EPE26048.1 - 1.9 9.4 5.0 2.3 9.1 1.3 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5339) Gpi1 PF05024.15 EPE26049.1 - 9.6e-76 254.0 8.7 9.6e-76 254.0 8.7 1.7 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Ferric_reduct PF01794.19 EPE26050.1 - 4.9e-18 65.4 11.0 6.1e-17 61.9 8.3 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EPE26050.1 - 1.1e-10 41.9 0.0 0.00019 21.6 0.0 2.7 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EPE26050.1 - 2.7e-10 40.3 0.1 1.3e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain DUF5534 PF17686.1 EPE26050.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5534) DPM3 PF08285.11 EPE26050.1 - 5.2 7.3 6.0 7.3 6.9 2.4 2.6 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Prefoldin PF02996.17 EPE26051.1 - 5e-32 110.3 0.1 2.2e-31 108.3 0.0 1.8 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 EPE26051.1 - 0.0002 21.3 0.4 0.0034 17.3 0.0 2.2 2 0 0 2 2 2 1 Prefoldin subunit Syntaxin-6_N PF09177.11 EPE26051.1 - 0.22 12.1 1.3 5.9 7.5 1.3 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal CRAL_TRIO PF00650.20 EPE26052.1 - 3e-35 121.3 0.0 4.6e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EPE26052.1 - 6.4e-07 29.5 0.1 1.4e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EPE26052.1 - 0.0079 16.4 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain W2 PF02020.18 EPE26053.1 - 4.5e-20 71.6 2.8 9.3e-20 70.6 2.8 1.5 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EPE26053.1 - 7.4e-12 44.5 7.9 0.00027 20.5 1.8 4.0 1 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EPE26053.1 - 4.5e-06 26.4 0.0 7.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 EPE26053.1 - 0.00011 21.8 4.7 0.013 15.2 1.5 3.6 2 1 1 3 3 3 1 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 EPE26053.1 - 0.00034 21.0 0.0 0.00067 20.1 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 EPE26053.1 - 0.0081 14.3 0.4 0.022 12.9 0.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EPE26053.1 - 0.071 12.0 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 L-fucokinase SAM_2 PF07647.17 EPE26054.1 - 1.4e-16 60.3 0.0 2.3e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EPE26054.1 - 2.6e-14 53.4 0.0 4.5e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EPE26054.1 - 2.6e-11 44.0 0.0 5.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 EPE26054.1 - 0.012 15.6 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SNF2_N PF00176.23 EPE26055.1 - 8.2e-71 238.5 0.0 1.2e-70 238.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EPE26055.1 - 2e-24 85.3 0.0 4e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EPE26055.1 - 1.6e-14 54.2 0.0 3.5e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE26055.1 - 4.5e-07 30.0 0.0 1.2e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EPE26055.1 - 6.6e-05 22.7 10.2 0.00013 21.7 10.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE26055.1 - 0.00036 20.3 5.9 0.00082 19.2 5.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UBA_4 PF14555.6 EPE26055.1 - 0.042 13.7 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 UBA-like domain zf-RING_UBOX PF13445.6 EPE26055.1 - 0.046 13.7 8.5 0.1 12.7 8.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 EPE26055.1 - 0.28 11.6 12.7 0.69 10.3 12.7 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 EPE26055.1 - 2.5 8.0 9.9 5 7.1 9.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE26055.1 - 3.1 7.8 10.2 11 6.1 10.3 2.0 1 1 0 1 1 1 0 zinc-RING finger domain SQS_PSY PF00494.19 EPE26056.1 - 6.1e-54 183.3 0.0 9.2e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Pyr_redox_2 PF07992.14 EPE26057.1 - 2.7e-54 184.4 0.2 3.3e-54 184.1 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE26057.1 - 5.8e-13 49.2 0.0 1.6e-10 41.4 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE26057.1 - 0.0069 15.7 2.7 3.8 6.7 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EcoR124_C PF12008.8 EPE26057.1 - 0.01 15.5 0.4 0.044 13.4 0.0 1.9 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal NAD_binding_7 PF13241.6 EPE26057.1 - 0.092 13.2 0.2 6.1 7.3 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding Acetyltransf_1 PF00583.25 EPE26058.1 - 8.7e-10 38.9 0.0 2e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE26058.1 - 4e-08 33.3 0.0 6.7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE26058.1 - 1.1e-07 32.1 0.0 3.8e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE26058.1 - 0.00018 21.4 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EPE26058.1 - 0.00044 20.3 0.0 0.00078 19.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EPE26058.1 - 0.07 13.2 0.0 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain S4 PF01479.25 EPE26059.1 - 3.6e-14 52.2 0.0 8.7e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EPE26059.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 S4 domain OmpH PF03938.14 EPE26059.1 - 0.51 10.7 15.1 0.16 12.3 10.7 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) VSG_B PF13206.6 EPE26059.1 - 2.7 7.2 9.4 4.2 6.5 9.4 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain AAA_11 PF13086.6 EPE26059.1 - 5.4 6.7 13.4 12 5.6 13.4 1.5 1 1 0 1 1 1 0 AAA domain Carn_acyltransf PF00755.20 EPE26060.1 - 1.9e-206 687.2 0.0 2.2e-206 687.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Eaf7 PF07904.13 EPE26061.1 - 3.1e-28 98.2 0.2 3.1e-28 98.2 0.2 2.0 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 DAG_kinase_N PF14513.6 EPE26061.1 - 7 6.8 8.0 26 5.0 8.0 1.8 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus Nucleo_P87 PF07267.11 EPE26061.1 - 8.4 5.1 8.5 11 4.7 8.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 GCP_C_terminal PF04130.13 EPE26062.1 - 1.5e-78 264.4 3.6 2.6e-78 263.6 0.2 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EPE26062.1 - 5.5e-31 108.3 0.1 9.3e-31 107.6 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF5315 PF17242.2 EPE26062.1 - 0.052 13.4 0.4 23 4.9 0.1 3.4 3 0 0 3 3 3 0 Disordered region of unknown function (DUF5315) CHD5 PF04420.14 EPE26062.1 - 0.087 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 CHD5-like protein ETC_C1_NDUFA5 PF04716.14 EPE26063.1 - 1.3e-25 88.9 0.2 1.1e-23 82.8 0.0 2.3 2 0 0 2 2 2 2 ETC complex I subunit conserved region LOR PF04525.12 EPE26064.1 - 1.6e-05 24.6 0.0 2.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 LURP-one-related Trypan_PARP PF05887.11 EPE26064.1 - 5.3 7.0 18.2 0.59 10.1 13.7 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Acetyltransf_1 PF00583.25 EPE26065.1 - 5.3e-07 29.9 0.0 7.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EPE26065.1 - 0.0025 17.9 0.3 0.0085 16.2 0.3 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE26065.1 - 0.0037 17.7 0.0 0.0049 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPE26065.1 - 0.018 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPE26065.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2046 PF09755.9 EPE26066.1 - 0.0021 17.3 3.3 0.0024 17.2 0.4 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Fib_alpha PF08702.10 EPE26066.1 - 0.033 14.4 1.2 4.1 7.6 0.4 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 EPE26066.1 - 0.081 13.4 1.3 1.7 9.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF1963 PF09234.10 EPE26066.1 - 0.1 13.0 0.1 0.16 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) SKA2 PF16740.5 EPE26066.1 - 0.16 11.8 7.5 0.072 12.9 2.8 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DivIC PF04977.15 EPE26066.1 - 0.18 11.6 0.2 0.18 11.6 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 EPE26066.1 - 0.24 12.0 11.7 4.8 7.9 0.4 2.5 2 0 0 2 2 2 0 SlyX TSC22 PF01166.18 EPE26066.1 - 0.28 11.5 0.2 0.28 11.5 0.2 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family End3 PF12761.7 EPE26066.1 - 1.6 8.9 10.0 3.3 7.8 0.1 2.6 3 0 0 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 MerR-DNA-bind PF09278.11 EPE26066.1 - 3.9 8.1 12.4 1.4 9.6 0.8 2.4 2 0 0 2 2 2 0 MerR, DNA binding MFS_1 PF07690.16 EPE26067.1 - 2e-32 112.5 31.5 8.8e-29 100.5 5.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE26067.1 - 2e-09 36.9 2.3 2e-09 36.9 2.3 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 EPE26067.1 - 0.32 9.4 5.0 0.13 10.6 1.5 2.0 2 1 1 3 3 3 0 Transmembrane secretion effector GDI PF00996.18 EPE26068.1 - 1.8e-187 623.2 0.0 2.1e-187 623.0 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 EPE26068.1 - 0.008 16.4 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EPE26068.1 - 0.09 13.3 0.2 0.23 12.0 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MRP-L47 PF06984.13 EPE26069.1 - 1.6e-19 69.8 0.2 2.7e-19 69.1 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.12 EPE26069.1 - 0.16 11.4 0.6 0.28 10.6 0.6 1.3 1 0 0 1 1 1 0 Clc-like MRP-L20 PF12824.7 EPE26069.1 - 2.8 8.1 7.3 0.65 10.1 3.1 2.0 2 1 1 3 3 3 0 Mitochondrial ribosomal protein subunit L20 Fungal_trans PF04082.18 EPE26072.1 - 1.5e-16 60.3 0.0 2.6e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EPE26072.1 - 2e-05 24.8 1.1 2e-05 24.8 1.1 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.12 EPE26072.1 - 0.00034 20.8 3.8 0.001 19.4 3.8 1.8 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EPE26072.1 - 7.7 7.6 27.6 0.069 14.0 5.8 3.4 4 0 0 4 4 4 0 C2H2-type zinc finger LRR_4 PF12799.7 EPE26073.1 - 2.9 8.5 8.6 2.4 8.7 0.5 3.7 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) eIF3g PF12353.8 EPE26075.1 - 2.8e-43 147.3 4.2 2.8e-43 147.3 4.2 1.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EPE26075.1 - 6e-17 61.2 0.1 1.1e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPE26075.1 - 0.003 17.4 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH_7 PF18586.1 EPE26075.1 - 0.061 13.7 0.2 0.12 12.7 0.2 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 HSP70 PF00012.20 EPE26076.1 - 1.4e-264 878.8 16.6 1.6e-264 878.6 16.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EPE26076.1 - 2.1e-15 56.4 5.0 2.1e-13 49.8 1.9 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EPE26076.1 - 0.0022 17.7 0.0 0.0069 16.1 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4363 PF14276.6 EPE26076.1 - 0.031 14.4 4.6 0.07 13.3 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Big_3_4 PF13754.6 EPE26076.1 - 0.052 13.3 0.0 2.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF2415 PF10313.9 EPE26077.1 - 1.8e-10 40.6 0.0 3.5e-09 36.4 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 EPE26077.1 - 0.00011 22.4 0.0 0.61 10.4 0.0 4.0 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPE26077.1 - 0.00032 21.5 3.7 1 10.3 0.0 5.5 6 0 0 6 6 6 1 WD domain, G-beta repeat PD40 PF07676.12 EPE26077.1 - 0.0092 15.9 0.1 14 5.8 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Get5_C PF18514.1 EPE26077.1 - 0.096 12.4 0.0 0.65 9.8 0.0 2.3 2 0 0 2 2 2 0 Get5 C-terminal domain DAO PF01266.24 EPE26078.1 - 6.9e-61 206.8 0.2 9.6e-61 206.3 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase PAH PF02671.21 EPE26078.1 - 1.5e-06 28.2 0.1 3.6e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Paired amphipathic helix repeat NAD_binding_8 PF13450.6 EPE26078.1 - 0.00048 20.3 0.9 0.0011 19.2 0.9 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EPE26078.1 - 0.034 13.5 2.2 0.052 12.9 1.2 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase TrkA_N PF02254.18 EPE26078.1 - 0.087 13.1 0.1 0.25 11.6 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.14 EPE26078.1 - 0.097 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE26078.1 - 0.15 10.8 0.8 0.23 10.1 0.8 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 EPE26078.1 - 0.16 11.9 0.3 0.33 10.9 0.3 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding ApbA PF02558.16 EPE26078.1 - 0.17 11.5 0.3 0.44 10.2 0.3 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 EPE26078.1 - 0.24 10.5 1.2 0.55 9.2 1.2 1.5 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EPE26078.1 - 0.28 10.2 0.5 0.43 9.6 0.5 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GMC_oxred_C PF05199.13 EPE26080.1 - 2.1e-12 47.8 0.0 2.7e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EPE26080.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase MFS_1 PF07690.16 EPE26081.1 - 3.5e-49 167.6 36.2 3.5e-49 167.6 36.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE26081.1 - 1.3e-10 40.8 30.8 1.8e-10 40.3 28.5 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EPE26081.1 - 3.7e-06 26.5 4.5 3.7e-06 26.5 4.5 2.7 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Aconitase PF00330.20 EPE26082.1 - 6.5e-161 536.4 0.1 8.2e-161 536.1 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EPE26082.1 - 2.7e-42 144.2 0.0 7.5e-42 142.8 0.0 1.8 2 0 0 2 2 2 1 Aconitase C-terminal domain DUF2418 PF10332.9 EPE26084.1 - 6.8e-35 119.5 0.4 6.8e-35 119.5 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.17 EPE26085.1 - 6.9e-33 112.8 0.1 7.9e-33 112.7 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.15 EPE26086.1 - 3.4e-28 98.7 0.7 3.9e-28 98.5 0.7 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EPE26086.1 - 0.00023 21.6 0.1 0.00044 20.6 0.1 1.5 1 1 0 1 1 1 1 ML-like domain EBP PF05241.12 EPE26087.1 - 6.8e-60 201.6 9.2 8e-60 201.3 9.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein Sprouty PF05210.13 EPE26087.1 - 0.044 14.2 0.2 0.15 12.5 0.1 1.8 2 0 0 2 2 2 0 Sprouty protein (Spry) WBP-1 PF11669.8 EPE26087.1 - 0.045 14.4 0.9 0.14 12.8 0.1 2.0 2 0 0 2 2 2 0 WW domain-binding protein 1 PHD PF00628.29 EPE26089.1 - 9.9e-07 28.6 9.4 2e-06 27.6 9.4 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 EPE26089.1 - 0.021 15.2 1.0 0.073 13.4 0.0 2.3 2 2 0 2 2 2 0 SET domain Glycos_transf_4 PF00953.21 EPE26090.1 - 8.7e-34 116.8 8.4 8.7e-34 116.8 8.4 2.3 4 0 0 4 4 4 1 Glycosyl transferase family 4 WD40 PF00400.32 EPE26091.1 - 1.4e-14 54.3 0.4 0.035 15.0 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EPE26091.1 - 4.3e-05 22.6 0.0 0.0015 17.6 0.0 2.4 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IBR PF01485.21 EPE26092.1 - 0.00032 20.9 8.1 0.00032 20.9 8.1 4.8 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain Aspzincin_M35 PF14521.6 EPE26094.1 - 6e-05 23.6 3.5 0.00043 20.9 2.4 2.7 2 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase SOG2 PF10428.9 EPE26095.1 - 0.9 8.7 17.8 0.98 8.5 17.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TMEM151 PF14857.6 EPE26095.1 - 2.4 7.0 9.8 3.1 6.6 9.8 1.1 1 0 0 1 1 1 0 TMEM151 family Macoilin PF09726.9 EPE26095.1 - 4.1 5.8 12.5 5.4 5.4 12.5 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EPE26095.1 - 8.8 5.1 9.4 10 4.9 9.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain HlyIII PF03006.20 EPE26096.1 - 3.3 7.4 16.0 0.018 14.8 5.8 2.1 2 1 1 3 3 3 0 Haemolysin-III related Tmemb_55A PF09788.9 EPE26096.1 - 3.4 6.7 8.3 1.1 8.3 1.6 2.5 2 0 0 2 2 2 0 Transmembrane protein 55A DUF4267 PF14087.6 EPE26097.1 - 1.8e-15 56.9 4.5 2.3e-15 56.6 4.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) MFS_1 PF07690.16 EPE26098.1 - 8.1e-38 130.2 51.5 6.4e-37 127.3 48.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE26098.1 - 3.6e-12 45.9 4.6 3.6e-12 45.9 4.6 3.3 3 2 0 3 3 3 1 Sugar (and other) transporter DUF3522 PF12036.8 EPE26098.1 - 0.12 12.6 0.3 0.12 12.6 0.3 3.3 3 2 1 4 4 4 0 Protein of unknown function (DUF3522) DUF2784 PF10861.8 EPE26098.1 - 0.18 11.8 5.7 5.1 7.2 0.7 2.9 2 1 0 2 2 2 0 Protein of Unknown function (DUF2784) OATP PF03137.20 EPE26098.1 - 8.4 4.5 8.5 0.38 9.0 0.2 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 EPE26099.1 - 7.6e-27 94.2 0.0 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 FlbD PF06289.11 EPE26099.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins p450 PF00067.22 EPE26100.1 - 2.9e-29 102.1 0.0 3.8e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF5397 PF17375.2 EPE26100.1 - 0.0066 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5397) Mob1_phocein PF03637.17 EPE26102.1 - 1.1e-22 80.8 0.0 2.2e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 EPE26102.1 - 0.16 12.3 3.8 0.31 11.3 3.8 1.5 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases cobW PF02492.19 EPE26103.1 - 2.3e-44 151.1 0.3 3.5e-44 150.5 0.3 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EPE26103.1 - 9.3e-06 25.6 0.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase CobW_C PF07683.14 EPE26103.1 - 0.0081 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 EPE26103.1 - 0.016 15.6 0.0 0.049 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 EPE26103.1 - 0.016 15.3 0.0 0.044 13.9 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 EPE26103.1 - 0.017 14.2 0.5 3 6.8 0.0 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 EPE26103.1 - 0.02 14.7 1.7 0.32 10.8 1.7 2.2 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EPE26103.1 - 0.02 14.6 0.2 0.033 13.9 0.2 1.6 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EPE26103.1 - 0.021 14.4 1.4 0.53 9.8 1.4 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain APS_kinase PF01583.20 EPE26103.1 - 0.046 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 EPE26103.1 - 0.047 13.0 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 EPE26103.1 - 0.048 13.6 0.1 0.075 12.9 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EPE26103.1 - 0.057 13.9 0.4 0.19 12.2 0.1 2.0 2 1 0 2 2 2 0 ABC transporter TsaE PF02367.17 EPE26103.1 - 0.057 13.4 0.1 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EPE26103.1 - 0.061 13.6 0.3 0.2 12.0 0.0 2.0 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 EPE26103.1 - 0.069 12.4 0.4 4.5 6.5 0.0 2.4 3 0 0 3 3 3 0 Septin AAA_23 PF13476.6 EPE26103.1 - 0.076 13.5 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EPE26103.1 - 0.085 13.4 0.1 0.26 11.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EPE26103.1 - 0.12 12.1 0.2 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EPE26103.1 - 0.16 12.0 0.0 0.46 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain CAP_N PF01213.19 EPE26104.1 - 0.13 11.7 4.3 0.2 11.1 4.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RGS PF00615.19 EPE26105.1 - 5.3e-34 117.0 0.0 1.3e-33 115.7 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 EPE26105.1 - 9.7e-25 86.4 0.0 2.9e-20 72.1 0.0 3.3 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDC73_C PF05179.14 EPE26106.1 - 1.6e-57 193.6 0.0 2.6e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal DUF45 PF01863.17 EPE26107.1 - 0.077 13.0 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 Dak1 PF02733.17 EPE26108.1 - 5.8e-83 278.4 0.0 6.6e-83 278.2 0.0 1.0 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EPE26109.1 - 7e-45 153.0 0.2 2.7e-44 151.1 0.0 2.0 2 0 0 2 2 2 1 DAK2 domain TF_Zn_Ribbon PF08271.12 EPE26110.1 - 0.0065 16.0 0.6 0.14 11.7 0.2 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding p450 PF00067.22 EPE26111.1 - 5e-51 173.9 0.0 8.5e-51 173.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF1690 PF07956.11 EPE26112.1 - 0.059 13.8 4.0 0.074 13.5 4.0 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) SR-25 PF10500.9 EPE26112.1 - 0.22 11.1 13.9 0.23 11.1 13.9 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC106 PF15794.5 EPE26112.1 - 0.26 11.0 7.9 0.29 10.8 7.9 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Sec62 PF03839.16 EPE26112.1 - 1.2 8.5 5.3 1.3 8.4 5.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DASH_Ask1 PF08655.10 EPE26113.1 - 8.3e-05 22.4 6.3 0.01 15.7 0.3 2.4 2 0 0 2 2 2 2 DASH complex subunit Ask1 Rhodanese PF00581.20 EPE26114.1 - 3.4e-15 56.5 0.0 4.5e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain RlmM_FDX PF18125.1 EPE26114.1 - 0.0093 16.4 0.1 0.079 13.5 0.0 2.2 2 0 0 2 2 2 1 RlmM ferredoxin-like domain Yip1 PF04893.17 EPE26115.1 - 6e-12 45.6 17.4 6e-12 45.6 17.4 1.6 1 1 1 2 2 2 1 Yip1 domain ubiquitin PF00240.23 EPE26116.1 - 2.5e-31 107.2 0.8 5.9e-31 106.0 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_L40e PF01020.17 EPE26116.1 - 1.4e-30 104.9 10.7 2.7e-30 104.0 10.7 1.5 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EPE26116.1 - 1.6e-13 50.2 1.0 3.2e-13 49.3 0.4 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like zf-RRN7 PF11781.8 EPE26116.1 - 3.8e-06 26.5 2.7 3.8e-06 26.5 2.7 2.4 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ubiquitin_2 PF14560.6 EPE26116.1 - 0.001 19.5 0.1 0.0033 17.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EPE26116.1 - 0.039 13.9 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EPE26116.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EPE26116.1 - 0.059 13.7 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain eIF-5a PF01287.20 EPE26117.1 - 6.7e-27 93.4 2.0 9.4e-27 92.9 2.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EPE26117.1 - 0.00093 19.2 0.4 0.0022 18.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.12 EPE26118.1 - 1.6e-127 426.4 6.4 2e-127 426.1 6.4 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 EPE26118.1 - 6.6e-05 21.5 5.5 9.9e-05 20.9 5.5 1.5 1 1 0 1 1 1 1 Exocyst complex component Sec3 FPP PF05911.11 EPE26118.1 - 0.0051 15.1 0.7 0.32 9.1 0.1 2.2 2 0 0 2 2 2 2 Filament-like plant protein, long coiled-coil CCDC144C PF14915.6 EPE26118.1 - 0.013 14.7 0.1 0.023 13.8 0.1 1.3 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Exo70 PF03081.15 EPE26118.1 - 0.015 14.4 0.0 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Cep57_MT_bd PF06657.13 EPE26118.1 - 0.044 14.2 0.2 22 5.6 0.0 2.8 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 GAS PF13851.6 EPE26118.1 - 0.092 12.1 0.6 0.21 10.9 0.6 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding LXG PF04740.12 EPE26118.1 - 0.097 12.4 1.8 7.3 6.2 0.0 2.9 3 0 0 3 3 3 0 LXG domain of WXG superfamily Mer2 PF09074.10 EPE26118.1 - 0.099 12.4 4.9 0.41 10.4 0.2 2.9 3 0 0 3 3 3 0 Mer2 DUF4795 PF16043.5 EPE26118.1 - 0.11 12.0 0.8 0.27 10.8 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) RabGAP-TBC PF00566.18 EPE26119.1 - 2.9e-19 69.6 0.0 4.5e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMS1_N PF10433.9 EPE26120.1 - 7e-64 216.2 0.0 1.2e-63 215.4 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term GTP_EFTU PF00009.27 EPE26121.1 - 2.5e-34 118.5 1.8 3.5e-34 118.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EPE26121.1 - 2.2e-19 69.5 0.0 6.3e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EPE26121.1 - 5.8e-08 33.0 2.4 1.6e-06 28.4 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 EPE26121.1 - 2.6e-07 30.4 0.2 1.2e-06 28.4 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 EPE26121.1 - 8e-07 29.2 0.2 6.5e-06 26.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 EPE26121.1 - 0.00028 21.1 0.0 0.00079 19.6 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EPE26121.1 - 0.0012 18.7 0.0 0.0037 17.1 0.0 1.9 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.22 EPE26121.1 - 0.029 14.0 0.0 0.16 11.6 0.0 2.3 1 1 0 1 1 1 0 Ras family ATG22 PF11700.8 EPE26122.1 - 8.7e-132 440.1 25.9 1e-131 439.9 25.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EPE26122.1 - 6.3e-12 45.1 30.5 5.3e-07 28.9 3.1 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily BAR_2 PF10455.9 EPE26123.1 - 3.7e-63 213.3 0.3 5.4e-63 212.8 0.3 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EPE26123.1 - 1.4e-20 74.0 3.6 1.9e-19 70.3 3.6 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EPE26123.1 - 0.00047 19.9 0.4 0.029 14.1 0.0 2.5 2 0 0 2 2 2 1 BAR domain of APPL family YdjC PF04794.12 EPE26123.1 - 0.06 13.3 0.8 0.14 12.2 0.2 1.8 1 1 1 2 2 2 0 YdjC-like protein DUF1993 PF09351.10 EPE26123.1 - 0.58 10.3 3.9 0.46 10.6 0.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) NAT PF04768.13 EPE26124.1 - 2.5e-50 170.4 0.0 4.9e-50 169.5 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase DnaJ_C PF01556.18 EPE26125.1 - 5.5e-30 104.4 0.0 8.4e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EPE26125.1 - 3e-21 75.3 1.1 3e-21 75.3 1.1 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EPE26125.1 - 8.8e-14 51.6 17.4 1.5e-13 50.9 17.4 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EPE26125.1 - 0.084 12.9 4.5 5.1 7.2 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 EPE26125.1 - 5.6 7.2 7.9 3 8.1 0.7 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 Fungal_trans PF04082.18 EPE26126.1 - 1.9e-09 37.0 0.0 3.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE26126.1 - 1.4e-08 34.7 8.0 2.8e-08 33.8 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.26 EPE26127.1 - 1.5e-46 158.3 0.2 1.9e-46 157.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EPE26127.1 - 7.7e-14 50.8 1.8 7.7e-14 50.8 1.8 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal NUP214 PF16755.5 EPE26128.1 - 4.4e-09 36.0 0.1 3.9e-08 32.9 0.0 2.3 2 1 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Nucleoporin_FG PF13634.6 EPE26128.1 - 0.00018 22.3 16.5 0.00018 22.3 16.5 9.0 5 2 3 8 8 8 2 Nucleoporin FG repeat region ANAPC4_WD40 PF12894.7 EPE26128.1 - 0.0085 16.4 0.0 0.031 14.6 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain NatB_MDM20 PF09797.9 EPE26129.1 - 2.1e-58 198.1 1.2 8.9e-58 196.0 1.2 2.0 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit 2OG-FeII_Oxy_3 PF13640.6 EPE26130.1 - 0.12 13.2 0.0 0.24 12.3 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily zf-C3HC4 PF00097.25 EPE26131.1 - 5.6e-06 26.1 10.7 1.2e-05 25.1 10.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPE26131.1 - 1e-05 25.6 12.4 1e-05 25.6 12.4 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EPE26131.1 - 2e-05 24.4 16.9 3.3e-05 23.6 11.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE26131.1 - 0.00015 21.8 12.4 0.00033 20.6 12.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EPE26131.1 - 0.00031 20.5 10.9 0.00031 20.5 10.9 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE26131.1 - 0.00098 19.4 15.5 0.00098 19.4 15.5 1.7 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 EPE26131.1 - 0.0011 18.9 10.0 0.0011 18.9 10.0 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zinc_ribbon_2 PF13240.6 EPE26131.1 - 0.069 12.9 5.1 9.9 6.0 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon domain UPF0547 PF10571.9 EPE26131.1 - 0.085 13.0 7.6 0.36 10.9 2.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_6 PF14835.6 EPE26131.1 - 0.092 12.6 7.4 0.22 11.4 7.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 EPE26131.1 - 8.4 6.8 11.3 33 4.9 11.3 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain Ilm1 PF10311.9 EPE26132.1 - 1.7e-60 203.4 4.0 2e-60 203.2 4.0 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 VKOR PF07884.14 EPE26132.1 - 0.38 11.0 4.5 0.61 10.3 4.5 1.4 1 0 0 1 1 1 0 Vitamin K epoxide reductase family Prenyltrans PF00432.21 EPE26133.1 - 6.9e-38 128.1 9.6 1.8e-08 34.0 1.5 6.8 6 1 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EPE26133.1 - 8.1e-05 21.9 0.0 0.00028 20.1 0.0 1.8 3 0 0 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EPE26133.1 - 0.023 13.8 0.0 8.7 5.3 0.0 3.2 3 0 0 3 3 3 0 Squalene-hopene cyclase N-terminal domain SIS PF01380.22 EPE26134.1 - 6.7e-59 197.4 0.1 1e-31 109.5 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EPE26134.1 - 3.2e-17 63.0 0.0 6.6e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EPE26134.1 - 3.5e-10 39.9 0.0 7.9e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EPE26134.1 - 0.0051 15.7 0.0 0.0087 15.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 EPE26134.1 - 0.11 12.6 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 SIS domain AAA PF00004.29 EPE26135.1 - 6.7e-43 146.3 0.0 1.2e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EPE26135.1 - 4.2e-12 45.8 0.3 2.5e-10 40.2 0.1 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EPE26135.1 - 6e-11 42.0 0.2 1.7e-09 37.3 0.1 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 EPE26135.1 - 1.3e-08 35.4 0.0 6.1e-05 23.5 0.1 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EPE26135.1 - 2e-06 27.8 0.1 3.8e-05 23.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EPE26135.1 - 2.9e-06 27.5 0.0 9.2e-06 25.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EPE26135.1 - 7.1e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EPE26135.1 - 0.00022 21.5 0.1 0.006 16.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 EPE26135.1 - 0.00032 19.9 0.0 0.00084 18.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EPE26135.1 - 0.00046 20.7 0.0 0.0025 18.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EPE26135.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EPE26135.1 - 0.002 17.4 0.0 0.0043 16.3 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EPE26135.1 - 0.0034 17.5 0.0 0.01 16.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EPE26135.1 - 0.0041 16.5 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EPE26135.1 - 0.0045 16.7 0.2 0.013 15.3 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein TsaE PF02367.17 EPE26135.1 - 0.0046 17.0 0.0 0.0092 16.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EPE26135.1 - 0.006 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 EPE26135.1 - 0.0074 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EPE26135.1 - 0.0075 16.1 0.6 0.26 11.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EPE26135.1 - 0.0084 15.8 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 EPE26135.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EPE26135.1 - 0.021 14.2 0.7 0.13 11.6 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.6 EPE26135.1 - 0.022 14.5 0.0 0.057 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 EPE26135.1 - 0.038 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain DUF4200 PF13863.6 EPE26135.1 - 0.042 14.3 1.2 0.042 14.3 1.2 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) AAA_30 PF13604.6 EPE26135.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EPE26135.1 - 0.056 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 EPE26135.1 - 0.063 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EPE26135.1 - 0.074 12.6 0.1 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EPE26135.1 - 0.091 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EPE26135.1 - 0.11 11.8 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 EPE26135.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_13 PF13166.6 EPE26135.1 - 0.13 10.9 1.5 8.2 4.9 0.9 2.2 2 0 0 2 2 2 0 AAA domain DivIC PF04977.15 EPE26135.1 - 0.26 11.1 3.7 2.3 8.1 1.6 2.7 2 0 0 2 2 2 0 Septum formation initiator AAA_23 PF13476.6 EPE26135.1 - 3.1 8.2 6.0 50 4.3 0.0 2.6 3 1 0 3 3 2 0 AAA domain Enolase_C PF00113.22 EPE26136.1 - 3.5e-150 499.2 0.0 4.5e-150 498.8 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EPE26136.1 - 1.4e-58 196.7 0.3 2.7e-58 195.8 0.3 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EPE26136.1 - 6.7e-05 22.5 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like eIF3_subunit PF08597.10 EPE26137.1 - 1.1e-74 251.5 30.8 1.2e-74 251.3 30.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Prominin PF05478.11 EPE26137.1 - 0.11 10.4 0.8 0.18 9.8 0.8 1.3 1 0 0 1 1 1 0 Prominin Nop53 PF07767.11 EPE26137.1 - 0.22 10.9 27.7 0.34 10.3 19.4 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Glyco_hydro_3_C PF01915.22 EPE26138.1 - 7.1e-53 179.6 0.2 1.1e-52 179.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE26138.1 - 4.6e-36 124.8 0.0 7e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE26138.1 - 3.6e-15 55.8 0.0 8.6e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain tRNA-synt_1b PF00579.25 EPE26144.1 - 6.2e-57 193.1 0.0 8.3e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Peptidase_M3 PF01432.20 EPE26145.1 - 2.6e-121 406.1 0.0 4.2e-121 405.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 EPE26145.1 - 0.043 13.5 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like DNA_pol3_delt_C PF14840.6 EPE26145.1 - 0.062 13.6 0.1 0.92 9.8 0.0 2.5 2 0 0 2 2 2 0 Processivity clamp loader gamma complex DNA pol III C-term ApoO PF09769.9 EPE26146.1 - 1.2e-43 148.1 1.3 2e-42 144.2 0.1 2.2 2 0 0 2 2 2 1 Apolipoprotein O DUF543 PF04418.12 EPE26146.1 - 0.49 10.4 3.7 11 6.1 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Pyr_redox_2 PF07992.14 EPE26148.1 - 4.8e-37 127.8 0.0 8.6e-37 127.0 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE26148.1 - 7.3e-08 32.9 0.0 1.2e-06 28.9 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_76 PF03663.14 EPE26149.1 - 1e-34 120.7 14.5 2.1e-34 119.6 14.5 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EPE26149.1 - 0.00015 21.0 0.7 0.069 12.2 0.0 2.7 1 1 2 3 3 3 3 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 EPE26149.1 - 0.015 13.8 0.2 0.054 12.0 0.2 1.7 1 1 1 2 2 2 0 Beta-L-arabinofuranosidase, GH127 WD40 PF00400.32 EPE26150.1 - 1.8e-55 183.6 24.1 4.2e-11 43.2 0.1 7.6 8 0 0 8 8 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE26150.1 - 3.6e-20 72.1 0.0 2e-05 24.8 0.1 6.0 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE26150.1 - 5.1e-09 36.3 0.0 0.0035 17.2 0.0 3.3 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EPE26150.1 - 4.8e-08 32.1 1.9 0.0074 15.0 0.1 4.1 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EPE26150.1 - 1.3e-06 27.7 0.4 0.14 11.1 0.0 4.9 3 2 3 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EPE26150.1 - 4.5e-06 26.2 0.0 0.00017 21.1 0.0 2.7 3 0 0 3 3 3 1 WD40-like domain PD40 PF07676.12 EPE26150.1 - 2.8e-05 23.9 4.2 0.57 10.2 0.1 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DUF1513 PF07433.11 EPE26150.1 - 3e-05 23.2 1.8 0.38 9.8 0.0 3.8 2 2 2 4 4 4 2 Protein of unknown function (DUF1513) PALB2_WD40 PF16756.5 EPE26150.1 - 0.00092 18.2 1.8 0.86 8.5 0.0 3.2 2 1 1 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 EPE26150.1 - 0.0033 15.8 0.0 0.0094 14.3 0.0 1.7 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Coatomer_WDAD PF04053.14 EPE26150.1 - 0.0097 15.0 0.0 12 4.8 0.1 3.0 1 1 1 3 3 3 0 Coatomer WD associated region Cytochrom_D1 PF02239.16 EPE26150.1 - 0.023 13.2 0.0 9.6 4.6 0.0 2.8 2 1 1 3 3 3 0 Cytochrome D1 heme domain GspH PF12019.8 EPE26150.1 - 0.039 14.4 0.0 9.3 6.7 0.0 3.2 2 1 1 3 3 3 0 Type II transport protein GspH Nbas_N PF15492.6 EPE26150.1 - 0.042 13.2 0.1 6.3 6.0 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 EPE26150.1 - 0.081 11.7 0.1 1.4 7.6 0.0 2.6 2 1 0 2 2 2 0 Nup133 N terminal like CHAP PF05257.16 EPE26150.1 - 0.41 11.3 2.4 1.3 9.7 0.4 2.5 2 1 0 2 2 2 0 CHAP domain DUF4643 PF15485.6 EPE26150.1 - 0.45 10.3 5.3 0.67 9.7 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) Exo_endo_phos PF03372.23 EPE26151.1 - 3.1e-13 49.8 0.0 6.4e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF2_N PF00176.23 EPE26152.1 - 3.2e-47 160.9 0.0 1.5e-42 145.6 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE26152.1 - 2.8e-08 34.1 0.1 7.9e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE26152.1 - 0.00094 19.2 0.0 0.094 12.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HET PF06985.11 EPE26153.1 - 3.4e-23 82.6 0.0 1e-22 81.1 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAM60A PF15396.6 EPE26153.1 - 0.063 13.3 0.1 0.063 13.3 0.1 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Glyco_hydro_62 PF03664.13 EPE26154.1 - 2.5e-56 191.0 2.3 3e-56 190.8 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 HlyIII PF03006.20 EPE26155.1 - 7.5e-51 173.0 17.9 9.4e-51 172.7 17.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related TssN PF17555.2 EPE26155.1 - 6.8 6.0 12.2 3.4 7.0 3.8 2.4 1 1 1 2 2 2 0 Type VI secretion system, TssN ABC2_membrane_5 PF13346.6 EPE26155.1 - 7.4 6.1 14.1 0.24 10.9 4.3 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein TRAM_LAG1_CLN8 PF03798.16 EPE26156.1 - 4.1e-43 147.4 22.1 5.1e-43 147.1 17.1 2.0 2 0 0 2 2 2 2 TLC domain COPI_C PF06957.11 EPE26157.1 - 0.026 13.3 0.1 0.037 12.8 0.1 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus BTB PF00651.31 EPE26158.1 - 0.00098 19.3 2.7 0.15 12.3 0.1 2.7 2 1 1 3 3 3 2 BTB/POZ domain DUF2953 PF11167.8 EPE26158.1 - 0.15 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) PGBA_N PF15436.6 EPE26160.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA N-terminal DUF4293 PF14126.6 EPE26161.1 - 0.046 14.0 0.1 0.072 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Mad3_BUB1_I PF08311.12 EPE26164.1 - 3.6e-44 149.7 0.5 1.3e-43 147.9 0.1 2.1 3 0 0 3 3 3 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 EPE26164.1 - 2e-10 40.5 0.0 6e-10 38.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.11 EPE26164.1 - 2.2e-10 40.5 0.0 9.4e-10 38.5 0.0 2.0 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.17 EPE26164.1 - 4e-08 32.9 0.0 9.8e-08 31.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 EPE26164.1 - 0.02 15.0 0.0 0.091 12.9 0.0 2.1 3 0 0 3 3 3 0 Putative Mad3/BUB1 like region 1 protein BTB PF00651.31 EPE26165.1 - 2e-06 28.0 0.2 2.4e-05 24.5 0.0 2.4 3 0 0 3 3 3 1 BTB/POZ domain RasGEF_N PF00618.20 EPE26166.1 - 0.075 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 RasGEF N-terminal motif Tubulin_C PF03953.17 EPE26166.1 - 0.088 13.0 0.0 0.19 11.9 0.0 1.5 2 0 0 2 2 2 0 Tubulin C-terminal domain Aegerolysin PF06355.13 EPE26167.1 - 7.1e-11 42.3 0.5 8.5e-11 42.1 0.5 1.1 1 0 0 1 1 1 1 Aegerolysin CwfJ_C_1 PF04677.15 EPE26169.1 - 5.5e-27 94.1 0.0 8.6e-26 90.2 0.0 2.4 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EPE26169.1 - 8.3e-16 58.7 0.2 1.6e-15 57.8 0.2 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 HIT PF01230.23 EPE26169.1 - 0.052 14.3 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 HIT domain K_oxygenase PF13434.6 EPE26169.1 - 0.076 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Cyclin_N PF00134.23 EPE26170.1 - 4.4e-11 42.6 2.6 3.1e-10 39.9 0.1 2.5 2 1 1 3 3 3 2 Cyclin, N-terminal domain DRIM PF07539.12 EPE26171.1 - 1.6e-200 667.6 1.2 1.6e-200 667.6 1.2 4.4 4 1 0 4 4 4 1 Down-regulated in metastasis Rcd1 PF04078.13 EPE26171.1 - 0.082 12.2 1.2 0.57 9.4 0.0 2.8 3 0 0 3 3 3 0 Cell differentiation family, Rcd1-like HEAT PF02985.22 EPE26171.1 - 0.13 12.6 0.8 8 7.0 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat Sec7_N PF12783.7 EPE26171.1 - 0.52 10.2 5.6 49 3.8 0.0 4.9 4 1 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal zf-DNL PF05180.12 EPE26172.1 - 1.6e-29 101.6 0.7 2.5e-29 101.0 0.7 1.3 1 0 0 1 1 1 1 DNL zinc finger Cullin PF00888.22 EPE26173.1 - 2.2e-198 660.8 10.1 3.2e-198 660.2 10.1 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EPE26173.1 - 8.9e-25 86.5 2.3 2.7e-24 85.0 2.3 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain Utp21 PF04192.12 EPE26173.1 - 0.0088 15.6 0.8 2 7.8 0.0 3.3 3 0 0 3 3 3 2 Utp21 specific WD40 associated putative domain MT0933_antitox PF14013.6 EPE26174.1 - 0.65 10.3 6.5 2.1 8.7 3.6 2.8 1 1 0 2 2 2 0 MT0933-like antitoxin protein DNA_pol_phi PF04931.13 EPE26175.1 - 2.1e-222 740.4 29.5 3.9e-222 739.6 29.5 1.4 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 EPE26175.1 - 0.36 10.2 27.9 0.032 13.7 22.5 1.9 2 0 0 2 2 2 0 SDA1 Helo_like_N PF17111.5 EPE26176.1 - 8.4e-11 41.6 2.9 8.4e-11 41.6 2.9 2.1 3 0 0 3 3 3 1 Fungal N-terminal domain of STAND proteins SLATT_5 PF18160.1 EPE26176.1 - 0.0015 17.9 1.3 0.003 16.9 1.3 1.5 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 SesA PF17107.5 EPE26176.1 - 0.014 15.6 1.5 0.014 15.6 1.5 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases INT_SG_DDX_CT_C PF15300.6 EPE26176.1 - 0.015 15.1 0.5 2.8 7.8 0.1 4.0 4 0 0 4 4 4 0 INTS6/SAGE1/DDX26B/CT45 C-terminus ApoC-I PF04691.12 EPE26176.1 - 0.018 14.9 0.7 0.052 13.5 0.1 2.2 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Spc7 PF08317.11 EPE26176.1 - 0.019 13.9 4.3 0.17 10.7 0.7 2.6 2 0 0 2 2 2 0 Spc7 kinetochore protein FH2 PF02181.23 EPE26176.1 - 0.033 13.3 7.8 1.2 8.1 0.6 2.7 2 0 0 2 2 2 0 Formin Homology 2 Domain L27_N PF09060.10 EPE26176.1 - 0.041 13.9 2.3 1.1 9.3 0.6 2.6 2 0 0 2 2 2 0 L27_N PilJ PF13675.6 EPE26176.1 - 0.059 13.4 2.5 0.36 10.9 0.0 3.1 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF948 PF06103.11 EPE26176.1 - 0.091 13.0 0.0 0.72 10.2 0.0 2.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Goodbye PF17109.5 EPE26176.1 - 0.42 11.1 2.5 16 5.9 0.1 3.5 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain DUF812 PF05667.11 EPE26176.1 - 0.67 8.8 8.9 0.29 10.0 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF2408 PF10303.9 EPE26176.1 - 1.5 9.4 5.7 0.89 10.1 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) TMF_DNA_bd PF12329.8 EPE26176.1 - 2.4 8.2 14.5 2.5 8.1 1.0 4.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 EPE26176.1 - 2.8 8.0 9.0 0.25 11.4 0.8 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EPE26176.1 - 7 6.7 9.6 0.19 11.8 0.3 3.0 3 0 0 3 3 3 0 Laminin Domain II SF-assemblin PF06705.11 EPE26176.1 - 8.3 5.7 7.7 2.1 7.7 0.1 2.5 3 0 0 3 3 3 0 SF-assemblin/beta giardin NACHT PF05729.12 EPE26177.1 - 1.8e-06 28.0 0.0 3.9e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EPE26177.1 - 0.00021 21.7 0.0 0.00073 20.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EPE26177.1 - 0.0018 18.6 0.0 0.036 14.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF829 PF05705.14 EPE26177.1 - 0.015 15.2 0.0 0.048 13.6 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.7 EPE26177.1 - 0.023 15.3 0.1 0.074 13.6 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.14 EPE26177.1 - 0.03 13.8 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 EPE26177.1 - 0.035 13.8 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein RNA_helicase PF00910.22 EPE26177.1 - 0.14 12.5 0.2 1.8 9.0 0.0 3.0 4 0 0 4 4 4 0 RNA helicase Peptidase_M56 PF05569.11 EPE26178.1 - 0.0041 16.4 0.0 0.006 15.8 0.0 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 Stevor PF17410.2 EPE26178.1 - 0.0043 16.6 0.0 0.0079 15.8 0.0 1.4 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF4690 PF15756.5 EPE26178.1 - 0.0078 16.8 1.2 0.019 15.5 0.4 2.1 2 0 0 2 2 2 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 EPE26178.1 - 0.012 15.7 1.2 0.02 15.0 1.2 1.4 1 0 0 1 1 1 0 Podoplanin BatD PF13584.6 EPE26178.1 - 0.024 13.5 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance MLANA PF14991.6 EPE26178.1 - 0.024 14.9 0.0 0.075 13.3 0.0 1.8 2 0 0 2 2 2 0 Protein melan-A DUF2207 PF09972.9 EPE26178.1 - 0.039 12.7 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 EPE26178.1 - 0.12 12.2 0.7 0.23 11.4 0.7 1.3 1 0 0 1 1 1 0 TMEM154 protein family Phage_holin_3_6 PF07332.11 EPE26178.1 - 0.31 11.1 0.1 0.31 11.1 0.1 1.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Mid2 PF04478.12 EPE26178.1 - 0.62 9.9 3.2 0.5 10.2 0.6 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF515 PF04415.12 EPE26178.1 - 4.7 5.5 4.5 6.5 5.0 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Thi4 PF01946.17 EPE26179.1 - 1.1e-116 388.1 0.1 1.3e-116 387.8 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EPE26179.1 - 4.7e-07 29.7 1.5 1.9e-06 27.7 1.0 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE26179.1 - 4.3e-05 23.7 0.1 0.00015 22.0 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPE26179.1 - 5.5e-05 22.4 0.1 0.00017 20.8 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EPE26179.1 - 0.00088 19.3 0.4 0.0038 17.2 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EPE26179.1 - 0.0031 16.8 0.0 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE26179.1 - 0.0079 15.3 2.3 0.21 10.6 0.4 2.7 2 1 1 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 EPE26179.1 - 0.058 12.5 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EPE26179.1 - 0.11 11.7 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 EPE26179.1 - 0.13 11.0 0.2 0.19 10.5 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 EPE26179.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AP_endonuc_2 PF01261.24 EPE26180.1 - 1.2e-35 122.8 0.0 1.7e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Ish1 PF10281.9 EPE26180.1 - 0.089 13.1 0.3 3.8 7.9 0.0 2.7 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Coilin_N PF15862.5 EPE26180.1 - 1.6 8.5 16.1 11 5.8 10.8 2.4 2 0 0 2 2 2 0 Coilin N-terminus Mcm10 PF09332.11 EPE26180.1 - 5.4 6.3 27.7 0.082 12.3 16.0 2.1 2 0 0 2 2 2 0 Mcm10 replication factor Pectinesterase PF01095.19 EPE26181.1 - 0.058 12.1 0.3 0.064 12.0 0.3 1.0 1 0 0 1 1 1 0 Pectinesterase RED_N PF07808.13 EPE26183.1 - 0.0051 16.4 2.4 0.015 14.9 2.4 1.8 1 0 0 1 1 1 1 RED-like protein N-terminal region Exotox-A_target PF09102.10 EPE26183.1 - 1.1 9.3 4.1 0.84 9.6 0.2 2.4 2 1 0 2 2 2 0 Exotoxin A, targeting zf-UBR PF02207.20 EPE26184.1 - 1.1e-18 67.1 13.4 2.8e-18 65.8 13.4 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EPE26184.1 - 2.5e-05 24.0 0.1 5.5e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS PRIMA1 PF16101.5 EPE26184.1 - 0.19 11.8 1.5 0.45 10.6 1.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EPE26184.1 - 0.21 11.0 3.1 0.42 10.0 3.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-RING_11 PF17123.5 EPE26184.1 - 1.8 8.4 7.2 18 5.2 0.4 3.3 3 0 0 3 3 3 0 RING-like zinc finger UCR_UQCRX_QCR9 PF05365.12 EPE26185.1 - 2e-26 91.6 1.2 3.4e-26 90.9 1.2 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.10 EPE26186.1 - 7.8e-14 51.2 2.7 1.6e-13 50.2 2.7 1.6 1 0 0 1 1 1 1 Mago binding Spore_coat_CotO PF14153.6 EPE26186.1 - 0.036 14.0 4.9 0.042 13.8 4.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO FAM60A PF15396.6 EPE26186.1 - 0.29 11.1 3.7 0.38 10.7 3.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Peptidase_A21 PF03566.13 EPE26186.1 - 0.36 9.0 2.3 0.42 8.8 2.3 1.1 1 0 0 1 1 1 0 Peptidase family A21 Macoilin PF09726.9 EPE26186.1 - 0.62 8.6 6.9 0.65 8.5 6.9 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 EPE26186.1 - 6.4 5.4 6.1 7.5 5.2 6.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 EPE26186.1 - 6.8 5.9 8.3 8.6 5.6 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPR3 PF03666.13 EPE26186.1 - 8.9 5.0 7.7 11 4.7 7.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 IU_nuc_hydro PF01156.19 EPE26187.1 - 1.5e-83 280.9 0.0 1.7e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Egh16-like PF11327.8 EPE26188.1 - 9.5e-68 228.2 13.2 1.2e-67 227.9 13.2 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor AMP-binding PF00501.28 EPE26189.1 - 6e-24 84.4 0.0 9.1e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme CSTF2_hinge PF14327.6 EPE26190.1 - 3.7e-32 110.6 1.8 3.7e-32 110.6 1.8 2.3 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EPE26190.1 - 9.8e-21 73.4 0.0 1.4e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EPE26190.1 - 1.3e-13 50.3 2.4 1.3e-13 50.3 2.4 2.8 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 EPE26190.1 - 0.069 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Band_7 PF01145.25 EPE26191.1 - 4e-22 79.1 2.5 6.1e-22 78.5 2.5 1.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.8 EPE26191.1 - 0.1 12.8 0.3 0.22 11.7 0.3 1.5 1 0 0 1 1 1 0 Mediator complex subunit 2 Peptidase_S9 PF00326.21 EPE26193.1 - 2e-50 171.2 1.0 3.9e-50 170.3 1.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EPE26193.1 - 2.5e-07 29.7 0.2 5.4e-05 22.0 0.2 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Ank_3 PF13606.6 EPE26194.1 - 1.9e-12 46.2 0.0 0.72 10.6 0.0 5.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 EPE26194.1 - 1.1e-10 41.9 0.0 0.014 16.0 0.0 5.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE26194.1 - 7.4e-09 35.7 0.0 0.74 10.2 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE26194.1 - 3.6e-08 33.9 0.0 0.011 16.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EPE26194.1 - 1.2e-06 28.7 0.0 1.4 9.5 0.0 4.5 3 2 1 4 4 4 2 Ankyrin repeat TPT PF03151.16 EPE26195.1 - 2e-22 79.9 6.6 3e-22 79.3 6.6 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EPE26195.1 - 0.002 18.3 32.8 0.14 12.3 7.2 2.6 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EPE26195.1 - 0.014 14.6 12.7 0.0098 15.1 8.8 2.1 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport ARA70 PF12489.8 EPE26196.1 - 0.054 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Nuclear coactivator CHZ PF09649.10 EPE26196.1 - 0.57 9.7 2.6 1.6 8.3 2.6 1.7 1 0 0 1 1 1 0 Histone chaperone domain CHZ HET PF06985.11 EPE26197.1 - 3.4e-29 102.1 3.1 2.7e-28 99.1 3.1 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TMEM52 PF14979.6 EPE26197.1 - 0.088 12.7 0.4 19 5.2 0.0 2.6 2 0 0 2 2 2 0 Transmembrane 52 SWI-SNF_Ssr4 PF08549.10 EPE26198.1 - 1.4e-287 956.2 0.0 1.6e-287 956.0 0.0 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) CG-1 PF03859.16 EPE26198.1 - 0.19 11.5 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 CG-1 domain TFIIA PF03153.13 EPE26199.1 - 3.3 7.6 20.6 4.4 7.2 20.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 6PGD PF00393.19 EPE26200.1 - 2.7e-126 420.8 0.0 3.5e-126 420.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EPE26200.1 - 1.6e-49 168.1 0.0 2.5e-49 167.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EPE26200.1 - 0.031 14.5 0.1 0.18 12.0 0.0 2.4 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PGK PF00162.19 EPE26200.1 - 0.078 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase 2-Hacid_dh_C PF02826.19 EPE26200.1 - 0.14 11.5 0.0 0.42 9.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRM_1 PF00076.22 EPE26201.1 - 2.9e-17 62.2 0.0 4.7e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 EPE26201.1 - 0.13 12.0 0.8 2.8 7.7 0.3 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain AXE1 PF05448.12 EPE26202.1 - 1.4e-09 37.0 0.0 2.5e-06 26.4 0.0 3.0 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EPE26202.1 - 3.3e-06 26.7 0.2 4.3e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EPE26202.1 - 5.3e-06 27.2 0.6 6.6e-06 26.9 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 EPE26202.1 - 6.2e-06 26.3 0.0 1.3e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EPE26202.1 - 0.00016 21.3 0.0 0.00035 20.2 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EPE26202.1 - 0.00074 19.2 0.0 0.0043 16.7 0.0 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EPE26202.1 - 0.0014 17.9 0.0 0.0028 16.9 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Glyco_hydro_15 PF00723.21 EPE26203.1 - 1.9e-54 185.1 0.0 5.8e-52 177.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 CorA PF01544.18 EPE26204.1 - 1.3e-06 28.0 0.2 1.3e-06 28.0 0.2 3.2 3 0 0 3 3 3 2 CorA-like Mg2+ transporter protein DUF2681 PF10883.8 EPE26204.1 - 0.015 15.7 3.4 0.034 14.6 0.4 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) PI-PLC-X PF00388.19 EPE26205.1 - 0.035 13.7 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain ICL PF00463.21 EPE26207.1 - 0.18 10.3 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Isocitrate lyase family MAP17 PF15807.5 EPE26207.1 - 0.77 10.0 2.7 1 9.6 0.9 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF913 PF06025.12 EPE26207.1 - 2 7.3 3.9 2.8 6.8 3.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) YqfQ PF14181.6 EPE26207.1 - 5.2 7.2 7.9 7.1 6.8 7.9 1.2 1 0 0 1 1 1 0 YqfQ-like protein Prominin PF05478.11 EPE26208.1 - 0.025 12.6 0.1 0.027 12.4 0.1 1.0 1 0 0 1 1 1 0 Prominin RdRP PF05183.12 EPE26210.1 - 1.5e-181 605.1 0.0 1.9e-181 604.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Herpes_IE68 PF02479.16 EPE26210.1 - 0.084 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus immediate early protein PD40 PF07676.12 EPE26211.1 - 4.8e-05 23.2 0.4 0.057 13.4 0.2 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 EPE26211.1 - 0.00016 21.9 0.0 0.14 12.5 0.0 3.7 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPE26211.1 - 0.0059 17.4 2.3 42 5.2 0.0 5.1 4 1 1 5 5 5 1 WD domain, G-beta repeat BORG_CEP PF14957.6 EPE26211.1 - 1 10.6 6.9 2.3 9.4 2.5 2.4 2 0 0 2 2 2 0 Cdc42 effector DUF4939 PF16297.5 EPE26212.1 - 0.00089 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) U-box PF04564.15 EPE26212.1 - 0.033 14.4 0.1 0.076 13.2 0.1 1.5 1 0 0 1 1 1 0 U-box domain DUF2985 PF11204.8 EPE26213.1 - 1.7e-33 114.6 3.4 1.7e-33 114.6 3.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DUF805 PF05656.14 EPE26213.1 - 1.3 9.4 4.0 0.6 10.6 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF805) SLD5_C PF16922.5 EPE26214.1 - 2.3e-10 40.5 0.9 3.8e-10 39.8 0.3 1.7 2 0 0 2 2 2 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EPE26214.1 - 6.7e-07 29.8 0.5 5.2e-06 26.9 0.5 2.2 2 1 0 2 2 2 1 GINS complex protein DUF896 PF05979.12 EPE26214.1 - 0.11 12.4 0.2 0.3 11.0 0.1 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) SNase PF00565.17 EPE26215.1 - 1.5e-05 25.4 0.0 9.6e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Staphylococcal nuclease homologue DUF1652 PF07865.11 EPE26217.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) Rhodanese PF00581.20 EPE26218.1 - 8.1e-12 45.6 0.0 2.2e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Sugar_tr PF00083.24 EPE26220.1 - 3.8e-83 279.9 19.9 4.6e-83 279.6 19.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE26220.1 - 2.6e-23 82.5 21.2 2.6e-23 82.5 21.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE26220.1 - 8.7e-07 27.7 1.2 8.7e-07 27.7 1.2 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EPE26220.1 - 5.5e-06 25.9 1.6 5.5e-06 25.9 1.6 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB AF-4 PF05110.13 EPE26222.1 - 0.11 10.5 5.6 0.13 10.4 5.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein E7 PF00527.18 EPE26222.1 - 0.14 12.3 3.0 0.28 11.4 3.0 1.5 1 0 0 1 1 1 0 E7 protein, Early protein SDA1 PF05285.12 EPE26222.1 - 2.6 7.4 10.3 3.2 7.1 10.3 1.1 1 0 0 1 1 1 0 SDA1 Indigoidine_A PF04227.12 EPE26224.1 - 5.2e-120 400.2 0.0 9.1e-120 399.4 0.0 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 EPE26224.1 - 1.1e-22 80.7 1.6 5e-13 49.0 0.0 2.6 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EPE26224.1 - 0.0073 15.7 0.0 0.57 9.5 0.0 2.3 2 0 0 2 2 2 2 Phosphomethylpyrimidine kinase adh_short PF00106.25 EPE26226.1 - 8.6e-39 133.0 0.2 1.3e-38 132.5 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26226.1 - 4.8e-27 95.0 0.1 6.6e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE26226.1 - 8.6e-09 35.6 1.7 4.1e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 EPE26226.1 - 0.0001 21.9 0.1 0.00019 20.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EPE26226.1 - 0.0013 17.9 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.18 EPE26226.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 EPE26226.1 - 0.062 12.7 0.1 0.64 9.4 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase UPF0146 PF03686.13 EPE26226.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) FtsJ PF01728.19 EPE26226.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Polysacc_synt_2 PF02719.15 EPE26226.1 - 0.83 8.7 5.0 0.32 10.1 2.1 2.0 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein DUF2514 PF10721.9 EPE26227.1 - 0.24 11.4 5.7 0.32 11.0 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) TBCA PF02970.16 EPE26229.1 - 1.6e-26 92.5 5.3 1.9e-26 92.2 5.3 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A TEBP_beta PF07404.11 EPE26229.1 - 0.0067 15.8 0.4 0.0067 15.8 0.4 1.0 1 0 0 1 1 1 1 Telomere-binding protein beta subunit (TEBP beta) DUF16 PF01519.16 EPE26229.1 - 0.014 15.9 1.0 0.019 15.4 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 UPF0242 PF06785.11 EPE26229.1 - 0.027 14.6 0.9 0.033 14.3 0.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ntox1 PF15500.6 EPE26229.1 - 0.035 14.4 1.6 0.044 14.1 1.1 1.5 1 1 1 2 2 2 0 Putative RNase-like toxin, toxin_1 DUF4239 PF14023.6 EPE26229.1 - 0.086 12.6 0.5 0.11 12.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Csm1_N PF18504.1 EPE26229.1 - 0.089 13.1 6.6 0.05 13.9 3.2 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain V_ATPase_I PF01496.19 EPE26229.1 - 0.15 10.0 1.4 0.16 9.8 1.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 EPE26229.1 - 0.16 12.0 0.3 0.2 11.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 EPE26229.1 - 0.22 10.5 2.6 0.27 10.3 2.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 EPE26229.1 - 0.75 9.6 5.1 0.98 9.2 5.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Sugarporin_N PF11471.8 EPE26229.1 - 0.98 9.4 10.7 0.19 11.7 2.3 2.7 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension THOC7 PF05615.13 EPE26230.1 - 1.8e-46 157.7 9.9 1.8e-46 157.7 9.9 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 Elongin_A PF06881.11 EPE26231.1 - 2.6e-32 111.5 2.1 4.5e-32 110.7 2.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ubiquitin PF00240.23 EPE26232.1 - 1.1e-24 85.9 0.1 1.3e-24 85.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EPE26232.1 - 2.5e-14 52.9 0.1 2.7e-14 52.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EPE26232.1 - 0.00018 21.9 0.0 0.00035 21.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EPE26232.1 - 0.0023 17.8 0.0 0.0027 17.6 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain MFS_1 PF07690.16 EPE26233.1 - 3.5e-33 115.0 24.6 3.5e-33 115.0 24.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily TM140 PF14985.6 EPE26233.1 - 0.0049 16.4 2.4 0.011 15.3 0.4 2.4 2 0 0 2 2 2 1 TM140 protein family Holin_BhlA PF10960.8 EPE26233.1 - 0.2 11.6 1.0 2.9 7.9 0.1 2.9 3 0 0 3 3 3 0 BhlA holin family Glyco_hydro_88 PF07470.13 EPE26234.1 - 2e-86 290.2 2.2 2.3e-86 290.0 2.2 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Thioredoxin PF00085.20 EPE26235.1 - 1.4e-07 31.4 0.2 1.1e-06 28.5 0.3 2.1 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 EPE26235.1 - 0.11 11.8 0.3 0.4 10.0 0.4 1.7 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family HyaE PF07449.11 EPE26236.1 - 0.023 14.7 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin PF00085.20 EPE26236.1 - 0.086 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 EPE26237.1 - 7.9e-30 103.5 0.0 8.8e-30 103.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EPE26237.1 - 9.4e-06 25.6 0.0 1.1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family RRM_occluded PF16842.5 EPE26237.1 - 0.14 12.0 0.1 0.48 10.3 0.1 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif AA_permease PF00324.21 EPE26239.1 - 1.9e-137 458.8 45.4 2.8e-137 458.2 45.4 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE26239.1 - 8.6e-36 123.7 45.7 1.1e-35 123.3 45.7 1.0 1 0 0 1 1 1 1 Amino acid permease Internalin_N PF12354.8 EPE26239.1 - 2.1 8.5 0.0 2.1 8.5 0.0 3.4 4 1 1 5 5 5 0 Bacterial adhesion/invasion protein N terminal Epimerase PF01370.21 EPE26242.1 - 5.2e-14 52.3 0.0 1.5e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPE26242.1 - 1.2e-05 25.3 0.0 4.7e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EPE26242.1 - 1.2e-05 24.5 0.0 2e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EPE26242.1 - 2.7e-05 23.5 0.0 4.1e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EPE26242.1 - 6.1e-05 22.6 0.1 0.00012 21.6 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EPE26242.1 - 0.0023 17.1 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MFS_1 PF07690.16 EPE26243.1 - 6.9e-42 143.6 16.7 6.9e-42 143.6 16.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE26243.1 - 2.6e-13 49.6 5.7 2.6e-13 49.6 5.7 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EPE26243.1 - 3.2e-05 22.6 4.7 6.2e-05 21.6 4.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_8 PF01270.17 EPE26243.1 - 0.21 10.4 0.2 0.43 9.3 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolases family 8 DUF5381 PF17353.2 EPE26243.1 - 1.8 8.3 7.9 5.7 6.7 1.7 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5381) BTB PF00651.31 EPE26244.1 - 0.00017 21.8 0.0 0.00038 20.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain GBV-C_env PF12786.7 EPE26244.1 - 0.063 12.0 0.0 0.096 11.4 0.0 1.2 1 0 0 1 1 1 0 GB virus C genotype envelope zf-C3HC4_4 PF15227.6 EPE26244.1 - 0.097 12.8 3.3 1.9 8.7 1.4 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING adh_short PF00106.25 EPE26245.1 - 7.4e-24 84.3 0.3 7.3e-20 71.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26245.1 - 9e-10 38.5 0.1 3.2e-09 36.7 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE26245.1 - 6e-07 29.5 0.0 9.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EPE26245.1 - 7.3e-05 22.3 0.1 0.0002 20.9 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EPE26245.1 - 0.0032 17.0 0.0 0.0095 15.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4714 PF15833.5 EPE26246.1 - 0.015 15.2 0.8 0.74 9.8 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4714) Amidoligase_2 PF12224.8 EPE26247.1 - 1.1e-08 35.1 0.4 0.0016 18.2 0.1 3.0 2 1 0 2 2 2 2 Putative amidoligase enzyme MFS_1 PF07690.16 EPE26248.1 - 2.9e-34 118.5 42.3 3e-32 111.9 42.3 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE26248.1 - 1.1e-09 37.7 5.8 1.1e-09 37.7 5.8 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter Sulfotransfer_4 PF17784.1 EPE26249.1 - 1.3e-65 221.2 0.2 1.5e-65 221.0 0.2 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EPE26249.1 - 6e-05 23.5 0.0 0.00018 21.9 0.0 1.8 1 1 1 2 2 2 1 Sulfotransferase family DUF4131 PF13567.6 EPE26250.1 - 0.078 12.6 2.8 1.4 8.5 1.6 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) ketoacyl-synt PF00109.26 EPE26251.1 - 1.4e-71 241.0 0.0 2.5e-71 240.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EPE26251.1 - 2.6e-60 203.4 0.1 1.2e-59 201.3 0.0 2.1 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EPE26251.1 - 7.2e-48 163.3 0.0 1.2e-47 162.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EPE26251.1 - 5.2e-45 154.3 0.0 8.7e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE26251.1 - 2.9e-36 124.1 0.1 6.3e-36 123.0 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EPE26251.1 - 2.9e-18 66.4 0.0 1.1e-17 64.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EPE26251.1 - 1.6e-14 55.1 0.0 1.4e-13 52.1 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EPE26251.1 - 9.7e-14 51.8 0.0 9e-13 48.7 0.0 2.4 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 EPE26251.1 - 1.5e-11 44.4 0.0 5.4e-11 42.6 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EPE26251.1 - 2.6e-11 44.1 0.0 1e-10 42.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE26251.1 - 1.4e-10 41.2 0.0 7e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE26251.1 - 2.9e-09 37.4 0.0 8.6e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE26251.1 - 7.1e-09 35.7 0.0 3.8e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE26251.1 - 1.3e-06 28.0 0.0 4.6e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 EPE26251.1 - 1.4e-06 27.8 0.1 9.4e-06 25.2 0.1 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain adh_short PF00106.25 EPE26251.1 - 2.5e-06 27.1 0.0 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.12 EPE26251.1 - 0.0002 21.2 0.2 0.0005 19.9 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SAT PF16073.5 EPE26251.1 - 0.00023 21.0 0.3 0.17 11.6 0.4 2.4 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 EPE26251.1 - 0.00091 19.5 0.0 0.0022 18.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 EPE26251.1 - 0.01 15.4 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Methyltransf_16 PF10294.9 EPE26251.1 - 0.029 14.1 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase PAC4 PF16093.5 EPE26251.1 - 0.035 14.3 0.0 0.24 11.6 0.0 2.5 3 0 0 3 3 1 0 Proteasome assembly chaperone 4 DREV PF05219.12 EPE26251.1 - 0.095 11.8 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase ACP_syn_III PF08545.10 EPE26251.1 - 0.16 11.8 0.1 0.42 10.5 0.1 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CorA PF01544.18 EPE26252.1 - 1.9e-40 139.0 0.0 6.3e-40 137.3 0.0 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein NAD_binding_10 PF13460.6 EPE26253.1 - 1.8e-09 37.8 0.0 2.6e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE26253.1 - 0.0007 19.1 0.0 0.00092 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EPE26253.1 - 0.025 14.7 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_transf_25 PF01755.17 EPE26254.1 - 0.0001 22.2 0.2 0.00045 20.1 0.2 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) FAD_binding_3 PF01494.19 EPE26255.1 - 0.0001 21.7 0.0 0.00011 21.5 0.0 1.2 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EPE26256.1 - 1.3e-06 27.9 0.2 3.7e-06 26.4 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE26256.1 - 1.9e-05 24.1 0.1 0.0037 16.6 0.0 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE26256.1 - 0.00016 21.8 0.0 0.00039 20.6 0.0 1.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE26256.1 - 0.00028 20.6 0.1 0.00041 20.1 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase ADP_PFK_GK PF04587.15 EPE26256.1 - 0.014 14.0 0.0 0.017 13.7 0.0 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Thi4 PF01946.17 EPE26256.1 - 0.017 14.4 0.0 0.63 9.2 0.0 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 EPE26256.1 - 0.036 14.1 0.0 0.08 12.9 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding F-box-like PF12937.7 EPE26257.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 F-box-like HET PF06985.11 EPE26258.1 - 6e-26 91.5 0.9 6e-26 91.5 0.9 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) AIRC PF00731.20 EPE26260.1 - 6.5e-60 201.0 1.3 1.4e-59 199.9 1.3 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EPE26260.1 - 1.7e-50 171.0 0.0 2.5e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EPE26260.1 - 4.2e-18 64.8 0.0 8.8e-18 63.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EPE26260.1 - 3.1e-05 23.6 0.0 6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus XdhC_C PF13478.6 EPE26260.1 - 0.0027 18.2 0.0 0.052 14.1 0.0 2.6 2 1 1 3 3 3 1 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 EPE26260.1 - 0.0053 16.1 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Radical_SAM PF04055.21 EPE26260.1 - 0.0078 16.6 0.0 0.04 14.3 0.0 2.2 2 0 0 2 2 2 1 Radical SAM superfamily ATP-grasp_3 PF02655.14 EPE26260.1 - 0.018 15.1 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain NAD_binding_2 PF03446.15 EPE26260.1 - 0.02 15.1 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CbiG_C PF01890.16 EPE26260.1 - 0.044 14.3 0.0 0.13 12.9 0.0 1.9 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus ATPgrasp_N PF18130.1 EPE26260.1 - 0.055 14.0 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp N-terminal domain TrkA_N PF02254.18 EPE26260.1 - 0.12 12.7 0.1 0.65 10.3 0.1 2.3 1 1 0 1 1 1 0 TrkA-N domain Epimerase PF01370.21 EPE26260.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1192 PF06698.11 EPE26260.1 - 0.17 12.0 0.8 0.41 10.7 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) VIT1 PF01988.19 EPE26261.1 - 2e-05 24.6 0.0 2.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 VIT family TatC PF00902.18 EPE26261.1 - 0.0017 18.2 1.8 0.0029 17.4 1.8 1.6 1 1 0 1 1 1 1 Sec-independent protein translocase protein (TatC) TssN PF17555.2 EPE26261.1 - 0.032 13.6 1.5 0.046 13.1 1.5 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN Phage_tail_APC PF16778.5 EPE26261.1 - 0.077 12.9 0.1 0.077 12.9 0.1 1.8 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Cadherin_C_2 PF16492.5 EPE26261.1 - 0.18 12.6 0.7 0.51 11.1 0.7 1.8 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal NADH5_C PF06455.11 EPE26261.1 - 0.22 11.1 3.7 0.35 10.4 3.4 1.4 1 1 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus Pkinase PF00069.25 EPE26262.1 - 4.9e-22 78.5 0.0 6.7e-21 74.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE26262.1 - 2.8e-11 43.2 0.0 6.4e-05 22.4 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 EPE26262.1 - 0.018 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EPE26262.1 - 0.083 12.8 0.1 0.38 10.6 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Imm35 PF15567.6 EPE26263.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 35 SH3_2 PF07653.17 EPE26264.1 - 0.13 11.9 0.0 0.94 9.2 0.0 2.1 2 0 0 2 2 2 0 Variant SH3 domain MFS_2 PF13347.6 EPE26265.1 - 0.073 11.6 1.0 0.092 11.3 1.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein PAN_4 PF14295.6 EPE26267.1 - 0.0014 18.5 0.5 0.003 17.4 0.5 1.6 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 EPE26267.1 - 0.002 18.2 0.9 0.002 18.2 0.9 1.9 2 0 0 2 2 2 1 PAN-like domain RRM_1 PF00076.22 EPE26268.1 - 1.2e-17 63.5 0.6 2.6e-17 62.4 0.2 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPE26268.1 - 4.3e-05 23.1 0.0 5e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DPCD PF14913.6 EPE26268.1 - 0.03 13.7 0.1 0.041 13.2 0.1 1.2 1 0 0 1 1 1 0 DPCD protein family RRM_occluded PF16842.5 EPE26268.1 - 0.053 13.4 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Ank_2 PF12796.7 EPE26269.1 - 4.6e-12 46.4 0.3 5.6e-06 26.9 0.1 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE26269.1 - 2.8e-08 33.9 1.4 0.059 13.7 0.0 5.0 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE26269.1 - 4e-07 29.8 0.3 0.062 13.9 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EPE26269.1 - 1.3e-06 28.8 0.6 0.0014 19.2 0.0 4.6 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EPE26269.1 - 8.1e-06 26.1 5.7 0.034 14.6 0.4 4.6 5 0 0 5 5 5 2 Ankyrin repeat zf-C2H2_4 PF13894.6 EPE26269.1 - 0.0083 16.9 6.7 0.059 14.2 0.8 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 EPE26269.1 - 0.038 14.4 1.0 0.038 14.4 1.0 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type STIMATE PF12400.8 EPE26272.1 - 3.1e-42 144.0 1.9 3.1e-42 144.0 1.9 1.5 2 0 0 2 2 2 1 STIMATE family Virul_fac_BrkB PF03631.15 EPE26272.1 - 2.8 7.5 9.3 6.5 6.3 4.4 2.4 1 1 1 2 2 2 0 Virulence factor BrkB Pilosulin PF17499.2 EPE26273.1 - 0.15 12.3 0.1 0.22 11.7 0.1 1.2 1 0 0 1 1 1 0 Ant venom peptides Phage_holin_6_1 PF09682.10 EPE26275.1 - 0.068 13.6 0.0 0.098 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) GRAM PF02893.20 EPE26277.1 - 7.4e-06 25.8 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 GRAM domain DUF3292 PF11696.8 EPE26277.1 - 0.22 9.9 12.0 0.59 8.4 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3292) Peptidase_M22 PF00814.25 EPE26278.1 - 8.3e-49 166.7 0.3 8.8e-43 146.9 0.0 2.9 2 1 0 2 2 2 2 Glycoprotease family MFS_1 PF07690.16 EPE26279.1 - 8.4e-24 84.1 52.3 1.4e-23 83.5 48.4 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE26279.1 - 2.9e-06 26.4 13.0 2.9e-06 26.4 13.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MGC-24 PF05283.11 EPE26280.1 - 0.0079 16.6 7.2 0.0079 16.6 7.2 2.2 1 1 2 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin15 PF15672.5 EPE26280.1 - 0.011 15.3 4.7 0.011 15.3 4.7 2.0 1 1 0 2 2 2 0 Cell-membrane associated Mucin15 PTP_tm PF18861.1 EPE26280.1 - 0.011 15.8 0.2 0.017 15.1 0.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J TMEM154 PF15102.6 EPE26280.1 - 0.085 12.8 0.9 0.19 11.6 0.9 1.6 1 0 0 1 1 1 0 TMEM154 protein family Gemini_mov PF01708.16 EPE26280.1 - 0.15 11.8 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 Geminivirus putative movement protein Methyltransf_2 PF00891.18 EPE26281.1 - 1e-18 67.4 0.0 1.5e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EPE26281.1 - 0.026 15.2 0.0 0.061 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 EPE26281.1 - 0.13 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Acetyltransf_10 PF13673.7 EPE26282.1 - 2.3e-11 43.7 0.0 4.2e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE26282.1 - 1.4e-09 38.2 0.0 1.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE26282.1 - 5.2e-07 30.0 0.0 7.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EPE26282.1 - 0.0016 18.1 0.1 0.0022 17.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 EPE26282.1 - 0.0053 16.8 0.0 0.067 13.3 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EPE26282.1 - 0.0054 16.9 0.0 0.0068 16.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPE26282.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HET PF06985.11 EPE26283.1 - 2.2e-28 99.4 0.0 4.1e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clat_adaptor_s PF01217.20 EPE26284.1 - 4.8e-15 55.7 1.0 1.9e-06 27.9 0.0 2.9 2 1 0 2 2 2 2 Clathrin adaptor complex small chain Peptidase_S80 PF07230.11 EPE26284.1 - 0.011 14.1 0.0 0.015 13.7 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) Sua5_yciO_yrdC PF01300.18 EPE26285.1 - 3e-50 170.2 0.0 4.8e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EPE26285.1 - 1.2e-32 113.3 0.1 2.6e-32 112.2 0.1 1.5 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Proteasome PF00227.26 EPE26286.1 - 1.8e-46 158.0 0.3 2.3e-46 157.7 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit LMBR1 PF04791.16 EPE26287.1 - 0.63 8.9 7.9 1 8.2 7.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein RSS_P20 PF11757.8 EPE26287.1 - 3.3 8.2 8.7 3.5 8.1 1.6 3.1 3 0 0 3 3 3 0 Suppressor of RNA silencing P21-like N-terminal domain DUF4709 PF15821.5 EPE26287.1 - 4.6 7.6 17.9 0.39 11.0 8.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4709) NAGPA PF09992.9 EPE26289.1 - 0.041 14.1 0.2 0.13 12.5 0.1 1.7 1 1 0 1 1 1 0 Phosphodiester glycosidase APH PF01636.23 EPE26291.1 - 3.3e-10 40.3 0.0 4.6e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE26291.1 - 6.9e-06 25.8 0.0 5.3e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 EPE26291.1 - 0.013 14.9 0.0 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain BTB PF00651.31 EPE26292.1 - 3.1e-07 30.6 0.1 9.3e-07 29.1 0.1 1.9 1 0 0 1 1 1 1 BTB/POZ domain Fungal_trans PF04082.18 EPE26293.1 - 1.4e-11 43.9 0.3 2.4e-11 43.2 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 EPE26294.1 - 7.3e-34 116.9 0.0 9.3e-25 87.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26294.1 - 2e-19 70.1 0.0 3.8e-13 49.5 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE26294.1 - 1.4e-08 34.8 0.4 2.7e-08 33.9 0.0 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EPE26294.1 - 0.015 14.4 0.1 0.022 13.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EPE26294.1 - 0.026 14.0 0.0 0.038 13.4 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPE26294.1 - 0.057 13.3 0.0 0.29 11.0 0.0 2.1 1 1 0 1 1 1 0 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EPE26294.1 - 0.17 12.1 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TAP_C PF03943.13 EPE26296.1 - 0.054 13.2 0.6 0.27 10.9 0.2 2.4 2 0 0 2 2 2 0 TAP C-terminal domain Goodbye PF17109.5 EPE26296.1 - 0.084 13.3 0.5 1.8 9.0 0.0 2.9 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain AAA PF00004.29 EPE26297.1 - 4.7e-18 65.9 0.0 1.2e-17 64.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE26297.1 - 1.3e-05 25.6 0.2 7.3e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EPE26297.1 - 0.00092 19.5 0.3 0.0079 16.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain CCDC32 PF14989.6 EPE26297.1 - 0.0077 16.2 1.1 0.03 14.3 1.1 2.0 1 0 0 1 1 1 1 Coiled-coil domain containing 32 AAA_5 PF07728.14 EPE26297.1 - 0.031 14.3 0.0 0.096 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CPT PF07931.12 EPE26297.1 - 0.057 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein RuvB_N PF05496.12 EPE26297.1 - 0.1 12.3 0.1 0.3 10.8 0.1 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF3510 PF12022.8 EPE26297.1 - 2.6 8.5 5.7 0.83 10.0 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) p450 PF00067.22 EPE26298.1 - 4.4e-36 124.6 0.1 1.1e-23 83.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Oxidored_FMN PF00724.20 EPE26299.1 - 1.2e-64 218.8 0.0 8.4e-63 212.7 0.0 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family EAP30 PF04157.16 EPE26299.1 - 0.06 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family MARVEL PF01284.23 EPE26300.1 - 0.015 15.3 7.6 0.59 10.2 8.1 2.1 1 1 0 1 1 1 0 Membrane-associating domain SUR7 PF06687.12 EPE26300.1 - 0.063 12.9 11.6 0.68 9.5 11.6 2.1 1 1 0 1 1 1 0 SUR7/PalI family Claudin_3 PF06653.11 EPE26300.1 - 0.41 10.6 7.0 1.7 8.6 0.5 2.5 2 1 1 3 3 3 0 Tight junction protein, Claudin-like LptF_LptG PF03739.14 EPE26300.1 - 1.3 7.8 7.0 0.074 11.9 0.1 2.0 1 1 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG DUF1218 PF06749.12 EPE26300.1 - 1.7 9.2 6.6 0.65 10.6 1.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) Peptidase_C15 PF01470.17 EPE26302.1 - 1.5e-07 31.8 0.0 3.6e-07 30.5 0.0 1.6 1 1 1 2 2 2 1 Pyroglutamyl peptidase O-FucT PF10250.9 EPE26303.1 - 4.2e-14 53.0 0.0 3.5e-13 50.0 0.0 2.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase CoA_trans PF01144.23 EPE26304.1 - 3e-94 314.4 2.0 6.9e-55 185.8 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Thiolase_N PF00108.23 EPE26305.1 - 9.1e-69 231.7 0.3 1.4e-68 231.0 0.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lyase_1 PF00206.20 EPE26305.1 - 1.4e-46 159.3 0.0 2.6e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 Lyase Thiolase_C PF02803.18 EPE26305.1 - 5.8e-36 122.8 0.0 1.5e-35 121.5 0.0 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ADSL_C PF10397.9 EPE26305.1 - 2.1e-12 47.4 0.0 6.4e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus ketoacyl-synt PF00109.26 EPE26305.1 - 0.00028 20.6 0.1 0.00052 19.7 0.1 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EPE26305.1 - 0.012 15.4 0.1 0.12 12.2 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III HgmA PF04209.13 EPE26306.1 - 1.2e-142 475.6 0.0 1.4e-142 475.4 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Fungal_trans PF04082.18 EPE26307.1 - 6.1e-16 58.2 0.7 9.7e-16 57.6 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPE26307.1 - 7.8e-07 29.2 17.1 0.0029 18.0 4.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPE26307.1 - 1.3e-05 25.4 6.3 1.3e-05 25.4 6.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPE26307.1 - 4.4e-05 24.0 14.6 0.033 15.0 3.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE26307.1 - 0.05 13.9 7.6 0.053 13.8 1.5 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 EPE26307.1 - 1.5 9.4 9.4 5.2 7.6 2.4 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 EPE26307.1 - 4.7 7.3 14.4 0.047 13.7 0.9 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EPE26307.1 - 5.3 6.9 12.6 11 5.9 2.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type p450 PF00067.22 EPE26308.1 - 6.5e-65 219.7 0.0 1.7e-64 218.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EPE26309.1 - 1.2e-32 113.2 24.1 1.2e-32 113.2 24.1 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.9 EPE26309.1 - 0.4 10.9 1.0 6.6 7.0 0.0 2.6 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3267 PF11667.8 EPE26309.1 - 8.3 6.7 13.8 0.85 9.9 0.7 4.0 3 2 0 3 3 3 0 Putative zincin peptidase Glyco_transf_92 PF01697.27 EPE26310.1 - 4.6e-11 42.9 0.6 6.5e-11 42.4 0.6 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EPE26310.1 - 4.8e-11 43.0 0.4 1.1e-10 41.9 0.4 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 XisI PF08869.11 EPE26310.1 - 0.076 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 XisI protein Nuc_sug_transp PF04142.15 EPE26311.1 - 5.1e-22 78.4 5.7 5.9e-22 78.2 5.7 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter CrgA PF06781.12 EPE26311.1 - 0.15 12.1 0.2 0.47 10.5 0.2 1.8 1 0 0 1 1 1 0 Cell division protein CrgA SLATT_4 PF18186.1 EPE26311.1 - 0.98 9.0 2.8 21 4.7 3.6 2.4 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 FAD_binding_3 PF01494.19 EPE26312.1 - 4.3e-51 174.2 0.0 5.4e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE26312.1 - 4e-05 23.0 0.1 0.00017 20.9 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE26312.1 - 6.1e-05 23.2 0.6 0.00013 22.1 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EPE26312.1 - 8.2e-05 23.1 0.0 0.091 13.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE26312.1 - 0.00037 20.2 0.2 0.033 13.8 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EPE26312.1 - 0.00052 19.0 1.6 0.37 9.6 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 EPE26312.1 - 0.0013 17.5 0.1 0.0036 16.1 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 EPE26312.1 - 0.0098 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EPE26312.1 - 0.018 14.2 0.9 0.23 10.5 0.1 2.1 1 1 1 2 2 2 0 FAD binding domain Thi4 PF01946.17 EPE26312.1 - 0.039 13.2 0.1 0.062 12.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family R2K_2 PF18299.1 EPE26312.1 - 0.058 13.3 0.2 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 R2K_3 PF14243.6 EPE26312.1 - 0.066 13.2 0.8 0.13 12.3 0.8 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 NAD_binding_9 PF13454.6 EPE26312.1 - 0.13 12.3 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding IBR PF01485.21 EPE26313.1 - 1.8e-10 40.9 43.1 3.6e-06 27.1 13.0 3.6 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EPE26313.1 - 0.00022 21.0 0.8 0.00022 21.0 0.8 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE26313.1 - 0.029 14.4 6.5 0.029 14.4 6.5 4.0 3 1 0 3 3 3 0 RING-type zinc-finger DNA_ligase_ZBD PF03119.16 EPE26313.1 - 0.56 10.3 10.4 0.18 11.8 3.5 2.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain AAA PF00004.29 EPE26314.1 - 3.8e-18 66.2 0.0 6.5e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE26314.1 - 0.0023 18.3 0.0 0.0057 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EPE26314.1 - 0.0042 17.1 0.0 0.0095 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPE26314.1 - 0.011 16.0 0.1 0.045 14.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EPE26314.1 - 0.023 14.5 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 EPE26314.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 EPE26314.1 - 0.064 13.2 0.1 2.6 8.0 0.0 2.7 2 1 1 3 3 3 0 NACHT domain RNA_helicase PF00910.22 EPE26314.1 - 0.11 12.9 0.0 0.56 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 EPE26314.1 - 0.11 13.0 0.0 2 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Cyclase PF04199.13 EPE26315.1 - 1.7e-14 54.2 0.0 2.2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Cupin_3 PF05899.12 EPE26315.1 - 0.045 13.5 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Sigma70_r4 PF04545.16 EPE26315.1 - 0.19 11.3 0.0 5.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 Fructosamin_kin PF03881.14 EPE26316.1 - 3.3e-31 108.5 0.0 4.5e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase WD40 PF00400.32 EPE26317.1 - 6.6e-09 36.3 12.4 0.028 15.3 0.0 9.0 10 0 0 10 10 10 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE26317.1 - 1.2e-08 35.1 0.5 0.087 13.1 0.0 5.6 2 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PGAP1 PF07819.13 EPE26317.1 - 5.4e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EPE26317.1 - 0.00048 19.7 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EPE26317.1 - 0.0067 17.0 0.0 0.021 15.4 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.18 EPE26317.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) AAA_16 PF13191.6 EPE26317.1 - 0.023 15.1 0.0 0.1 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 EPE26317.1 - 0.046 13.6 0.0 0.29 11.0 0.0 2.5 3 1 0 3 3 3 0 NACHT domain DUF3328 PF11807.8 EPE26318.1 - 4.9e-46 157.3 0.6 6e-46 157.0 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Se-cys_synth_N PF12390.8 EPE26319.1 - 1e-09 38.4 8.8 27 5.1 0.0 12.5 6 3 2 8 8 8 0 Selenocysteine synthase N terminal CENP-O PF09496.10 EPE26319.1 - 6.5e-08 32.8 9.8 0.61 10.0 1.2 6.9 1 1 4 5 5 5 1 Cenp-O kinetochore centromere component TrbI_Ftype PF09677.10 EPE26319.1 - 2.5e-07 31.0 6.4 3 8.2 0.1 7.0 1 1 9 10 10 10 3 Type-F conjugative transfer system protein (TrbI_Ftype) Corona_NS2 PF04753.12 EPE26319.1 - 6.6e-05 23.5 1.6 18 6.0 0.0 6.9 1 1 8 10 10 10 0 Coronavirus non-structural protein NS2 baeRF_family8 PF18851.1 EPE26319.1 - 0.0015 18.6 23.0 41 4.2 0.1 8.7 1 1 5 8 8 8 0 Bacterial archaeo-eukaryotic release factor family 8 Pantoate_ligase PF02569.15 EPE26319.1 - 0.007 15.6 25.4 13 4.9 0.1 9.1 1 1 10 11 11 11 0 Pantoate-beta-alanine ligase YqcI_YcgG PF08892.11 EPE26319.1 - 0.022 14.6 13.0 17 5.1 0.9 6.4 1 1 7 8 8 8 0 YqcI/YcgG family AidB_N PF18158.1 EPE26319.1 - 0.034 14.1 10.6 72 3.3 0.2 5.3 1 1 1 2 2 2 0 Adaptive response protein AidB N-terminal domain IKBKB_SDD PF18397.1 EPE26319.1 - 0.039 13.2 4.7 2.1 7.6 0.0 4.3 1 1 4 5 5 5 0 IQBAL scaffold dimerization domain DUF3889 PF13028.6 EPE26319.1 - 0.062 13.2 15.1 6 6.9 0.8 5.7 1 1 5 7 7 7 0 Protein of unknown function (DUF3889) RE_XcyI PF09571.10 EPE26319.1 - 0.21 10.8 2.6 28 3.8 0.0 4.3 1 1 3 6 6 6 0 XcyI restriction endonuclease Egg_lysin PF01303.17 EPE26319.1 - 0.27 11.4 1.3 8 6.7 0.2 3.4 1 1 3 4 4 4 0 Egg lysin (Sperm-lysin) CdiI_2 PF18593.1 EPE26319.1 - 3.3 8.4 6.6 25 5.6 0.2 4.1 1 1 3 5 5 5 0 CdiI immunity protein GerPC PF10737.9 EPE26319.1 - 4.7 7.2 6.3 8.5 6.4 1.0 3.1 1 1 3 4 4 4 0 Spore germination protein GerPC gpW PF02831.15 EPE26319.1 - 5.3 7.0 19.3 38 4.3 0.8 7.3 1 1 6 7 7 7 0 gpW RRP7 PF12923.7 EPE26319.1 - 7.6 6.7 11.6 46 4.2 0.1 5.0 2 2 3 6 6 6 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Acetyltransf_1 PF00583.25 EPE26320.1 - 6.7e-12 45.7 0.0 9.3e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EPE26320.1 - 1.1e-10 42.4 0.0 1.5e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE26320.1 - 1e-05 25.9 0.0 1.5e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EPE26320.1 - 0.00043 20.4 0.0 0.00074 19.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPE26320.1 - 0.067 13.1 0.0 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EPE26320.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain COesterase PF00135.28 EPE26321.1 - 7.6e-62 209.8 0.0 1e-61 209.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE26321.1 - 2.6e-05 24.2 0.0 0.0002 21.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PTR2 PF00854.21 EPE26322.1 - 1.6e-40 139.2 2.8 2.6e-40 138.5 2.8 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EPE26322.1 - 5.9e-07 28.7 4.4 5.9e-07 28.7 4.4 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4026 PF13218.6 EPE26322.1 - 0.2 10.6 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) MCM PF00493.23 EPE26323.1 - 6.8e-101 336.0 0.0 1e-100 335.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EPE26323.1 - 1.2e-39 135.0 0.8 2.4e-39 134.0 0.8 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EPE26323.1 - 2.7e-29 101.4 4.1 2.7e-29 101.4 4.1 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EPE26323.1 - 1.1e-17 64.5 0.1 5.3e-17 62.3 0.1 2.3 2 0 0 2 2 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EPE26323.1 - 1e-05 25.0 0.0 0.00036 20.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EPE26323.1 - 3e-05 24.0 0.1 0.00023 21.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EPE26323.1 - 0.00083 19.2 0.0 0.0031 17.4 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TraT PF05818.12 EPE26323.1 - 0.0093 15.7 1.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 1 Enterobacterial TraT complement resistance protein AAA_lid_2 PF17863.1 EPE26323.1 - 0.029 14.2 0.1 0.082 12.8 0.1 1.7 1 0 0 1 1 1 0 AAA lid domain Sigma54_activat PF00158.26 EPE26323.1 - 0.12 12.0 0.1 3.7 7.2 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain Elf1 PF05129.13 EPE26323.1 - 0.13 12.4 0.3 0.32 11.1 0.3 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like AAA_32 PF13654.6 EPE26323.1 - 0.31 9.8 5.5 0.29 9.9 0.5 2.5 2 0 0 2 2 2 0 AAA domain p25-alpha PF05517.12 EPE26323.1 - 1.6 8.9 3.7 0.51 10.5 0.5 1.8 2 0 0 2 2 2 0 p25-alpha Mg_chelatase_C PF13335.6 EPE26323.1 - 2.2 9.0 8.2 0.57 10.9 2.6 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal FAD-oxidase_C PF02913.19 EPE26325.1 - 3.7e-57 193.8 0.1 6.3e-57 193.1 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EPE26325.1 - 3.1e-35 120.9 0.0 5e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 EPE26325.1 - 1.4e-05 24.0 0.2 3.9e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS AT_hook PF02178.19 EPE26325.1 - 0.11 12.4 1.3 0.27 11.2 1.3 1.7 1 0 0 1 1 1 0 AT hook motif Pyr_redox_2 PF07992.14 EPE26326.1 - 0.036 13.3 0.0 0.036 13.3 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Phytase-like PF13449.6 EPE26327.1 - 1.2e-35 123.9 0.0 1.5e-35 123.5 0.0 1.2 1 0 0 1 1 1 1 Esterase-like activity of phytase Caudal_act PF04731.12 EPE26327.1 - 0.075 13.4 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 Caudal like protein activation region Capsid_NCLDV PF04451.12 EPE26327.1 - 0.097 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Cellulase PF00150.18 EPE26328.1 - 6.2e-47 160.4 0.0 7.9e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-RAG1 PF10426.9 EPE26329.1 - 0.033 14.3 0.5 0.057 13.6 0.5 1.4 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain ArnB_C PF18677.1 EPE26330.1 - 0.024 14.7 0.1 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain DUF748 PF05359.11 EPE26332.1 - 0.14 12.3 0.1 13 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF748) Glyco_hydro_19 PF00182.19 EPE26334.1 - 0.046 13.6 0.1 0.076 12.9 0.1 1.3 1 0 0 1 1 1 0 Chitinase class I DUF1068 PF06364.12 EPE26334.1 - 0.13 12.1 0.6 0.21 11.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Podoplanin PF05808.11 EPE26334.1 - 2.7 8.1 11.1 0.082 13.0 4.7 1.7 2 0 0 2 2 2 0 Podoplanin TIG PF01833.24 EPE26335.1 - 0.00026 21.0 0.7 0.00077 19.5 0.1 2.2 2 0 0 2 2 2 1 IPT/TIG domain Reprolysin_5 PF13688.6 EPE26335.1 - 0.00035 20.8 0.0 0.00087 19.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 CARDB PF07705.11 EPE26335.1 - 0.00052 20.2 0.2 0.0022 18.2 0.2 2.1 1 0 0 1 1 1 1 CARDB Reprolysin_3 PF13582.6 EPE26335.1 - 0.035 14.6 0.1 0.075 13.6 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EPE26335.1 - 0.048 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF3254 PF11630.8 EPE26335.1 - 0.16 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) COG4 PF08318.12 EPE26339.1 - 5.1e-125 417.0 0.0 6.7e-125 416.6 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein E1-E2_ATPase PF00122.20 EPE26340.1 - 7.4e-47 159.2 1.0 7.4e-47 159.2 1.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EPE26340.1 - 1.8e-45 154.9 0.7 3.6e-45 153.9 0.7 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EPE26340.1 - 1.1e-19 69.9 0.1 2.5e-19 68.7 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 EPE26340.1 - 1.1e-18 68.3 5.6 4.4e-18 66.3 3.9 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPE26340.1 - 2.7e-13 49.8 0.0 5.4e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EPE26340.1 - 0.00032 20.5 1.0 0.00032 20.5 1.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.13 EPE26341.1 - 2.8e-36 124.0 0.0 4.9e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EPE26341.1 - 4.1e-09 35.6 0.5 1.1e-08 34.3 0.5 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF3533 PF12051.8 EPE26342.1 - 6.4e-90 301.8 19.9 7.7e-90 301.5 19.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) adh_short_C2 PF13561.6 EPE26343.1 - 6.9e-54 182.9 0.4 1e-53 182.3 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE26343.1 - 2.7e-45 154.2 2.8 3.5e-45 153.9 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE26343.1 - 1.7e-10 41.1 0.7 2.3e-10 40.7 0.7 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EPE26343.1 - 0.025 13.9 0.0 0.063 12.6 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1372 PF07116.11 EPE26343.1 - 0.037 14.2 0.1 0.085 13.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) COX16 PF14138.6 EPE26344.1 - 0.072 13.6 0.0 1.3 9.6 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 BatD PF13584.6 EPE26344.1 - 0.089 11.6 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF5446 PF17522.2 EPE26344.1 - 0.77 10.0 3.0 1.4 9.2 1.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Fungal_trans_2 PF11951.8 EPE26345.1 - 3.1e-11 42.7 0.0 4.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AGTRAP PF06396.11 EPE26346.1 - 0.015 15.1 0.3 0.015 15.1 0.3 2.6 2 1 1 3 3 3 0 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF4064 PF13273.6 EPE26349.1 - 0.046 14.0 0.4 0.082 13.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF3431 PF11913.8 EPE26350.1 - 0.029 14.2 0.7 0.034 13.9 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3431) DUF1752 PF08550.10 EPE26352.1 - 2.8e-08 33.5 7.6 5.6e-08 32.5 7.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) NgoMIV_restric PF09015.10 EPE26352.1 - 0.038 13.1 0.2 0.27 10.3 0.2 2.1 2 0 0 2 2 2 0 NgoMIV restriction enzyme adh_short PF00106.25 EPE26353.1 - 1.4e-34 119.3 0.0 2.1e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26353.1 - 1.5e-29 103.2 0.0 2.3e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EPE26353.1 - 0.0051 16.3 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EPE26353.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 KR domain ADH_zinc_N PF00107.26 EPE26353.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase p450 PF00067.22 EPE26354.1 - 1.5e-55 188.8 0.0 1.8e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EPE26355.1 - 1.2e-27 96.8 68.9 9e-24 84.0 42.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 EPE26356.1 - 1.6e-16 60.2 1.0 2.9e-16 59.3 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE26356.1 - 3.6e-08 33.4 9.3 7.4e-08 32.4 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PglZ PF08665.12 EPE26356.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 PglZ domain Styelin PF17562.2 EPE26356.1 - 0.2 12.0 0.2 0.53 10.7 0.2 1.7 1 0 0 1 1 1 0 Styelin HXXEE PF13787.6 EPE26357.1 - 0.035 14.9 1.6 0.065 14.0 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif DUF1479 PF07350.12 EPE26358.1 - 3.5e-165 549.8 0.0 4.1e-165 549.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 EPE26358.1 - 0.012 15.9 0.0 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) DUF3425 PF11905.8 EPE26359.1 - 8.8e-12 45.1 0.0 1.8e-11 44.1 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) MCM_bind PF09739.9 EPE26359.1 - 0.4 9.1 2.5 0.5 8.7 2.5 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor ubiquitin PF00240.23 EPE26360.1 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 EPE26361.1 - 0.00035 20.7 0.2 0.0015 18.7 0.0 2.0 2 0 0 2 2 2 1 TUG ubiquitin-like domain LUC7 PF03194.15 EPE26363.1 - 6.3e-71 239.0 0.6 7.5e-71 238.7 0.6 1.0 1 0 0 1 1 1 1 LUC7 N_terminus TelA PF05816.11 EPE26363.1 - 0.016 14.3 1.2 0.022 13.8 1.2 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Erp_C PF06780.11 EPE26363.1 - 0.046 13.7 0.1 0.065 13.2 0.1 1.2 1 0 0 1 1 1 0 Erp protein C-terminus Occludin_ELL PF07303.13 EPE26363.1 - 0.31 11.8 2.9 0.39 11.5 0.4 2.2 2 1 0 2 2 2 0 Occludin homology domain Gpi16 PF04113.14 EPE26364.1 - 2.2e-245 815.4 0.0 2.7e-245 815.1 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Glyco_hydro_18 PF00704.28 EPE26365.1 - 3.9e-87 292.9 8.8 4.6e-87 292.7 8.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 p450 PF00067.22 EPE26366.1 - 1.1e-74 251.8 0.0 1.8e-74 251.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 EPE26366.1 - 7.1e-31 107.5 0.0 1.2e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EPE26366.1 - 6.1e-24 84.9 0.0 3.7e-23 82.3 0.0 2.3 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 EPE26366.1 - 1.5e-12 48.1 0.1 5.3e-12 46.3 0.1 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EPE26366.1 - 0.0013 19.0 0.1 0.0044 17.3 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin domain Sugar_tr PF00083.24 EPE26367.1 - 2.1e-84 284.0 20.5 2.5e-84 283.7 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE26367.1 - 1e-36 126.6 17.4 1e-36 126.6 17.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPE26367.1 - 0.0004 18.9 2.6 0.0004 18.9 2.6 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Cons_hypoth698 PF03601.14 EPE26367.1 - 0.22 10.4 8.9 0.1 11.4 1.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical protein 698 OATP PF03137.20 EPE26367.1 - 0.77 8.0 13.1 0.28 9.4 0.8 3.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF1201 PF06716.11 EPE26367.1 - 3.6 7.7 5.5 31 4.7 1.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) Ribophorin_I PF04597.14 EPE26369.1 - 3.4e-150 501.1 0.4 3.9e-150 500.9 0.4 1.0 1 0 0 1 1 1 1 Ribophorin I Hexokinase_2 PF03727.16 EPE26370.1 - 5.6e-83 278.0 0.0 9.4e-83 277.3 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EPE26370.1 - 1.9e-70 236.9 0.0 5.1e-70 235.4 0.0 1.6 2 0 0 2 2 2 1 Hexokinase FGGY_N PF00370.21 EPE26370.1 - 0.033 13.7 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Ank PF00023.30 EPE26371.1 - 0.006 17.0 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EPE26371.1 - 0.027 15.1 0.0 0.92 10.1 0.0 2.3 1 1 0 2 2 2 0 Ankyrin repeats (3 copies) RNF220 PF15926.5 EPE26371.1 - 0.13 11.8 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 VTC PF09359.10 EPE26372.1 - 1.5e-96 323.0 0.0 1.5e-96 323.0 0.0 1.8 2 0 0 2 2 2 1 VTC domain DUF3328 PF11807.8 EPE26372.1 - 3.3e-22 79.4 0.3 1.2e-21 77.5 0.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF202 PF02656.15 EPE26372.1 - 7.8e-13 48.7 4.9 1.3e-12 48.0 3.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 EPE26372.1 - 8.7e-09 35.8 19.4 9.4e-06 25.8 0.1 4.1 2 1 2 4 4 4 3 SPX domain FixQ PF05545.11 EPE26372.1 - 0.00047 20.1 2.1 0.0095 15.9 0.9 2.4 2 0 0 2 2 2 1 Cbb3-type cytochrome oxidase component FixQ DUF1652 PF07865.11 EPE26372.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) PMP22_Claudin PF00822.20 EPE26372.1 - 0.23 11.3 1.2 0.64 9.9 0.6 1.8 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family NmrA PF05368.13 EPE26373.1 - 5.2e-15 55.6 0.0 6.8e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE26373.1 - 6.4e-15 55.5 0.0 9.9e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EPE26373.1 - 2.9e-05 24.5 0.0 6.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EPE26373.1 - 0.018 14.5 0.1 0.097 12.1 0.0 2.2 3 1 0 3 3 3 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EPE26373.1 - 0.022 14.9 0.0 0.095 12.8 0.0 2.1 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus zf-C3HC4_3 PF13920.6 EPE26375.1 - 0.0008 19.2 1.3 0.0026 17.6 1.5 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Hemerythrin PF01814.23 EPE26376.1 - 2.6e-09 37.8 0.2 4.2e-09 37.1 0.2 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain AXE1 PF05448.12 EPE26377.1 - 0.018 13.7 0.1 0.041 12.6 0.1 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Ppx-GppA PF02541.16 EPE26378.1 - 2.3e-41 142.1 0.0 3.3e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Glycolytic PF00274.19 EPE26378.1 - 0.055 12.2 0.1 23 3.6 0.0 3.1 2 1 0 3 3 3 0 Fructose-bisphosphate aldolase class-I GDA1_CD39 PF01150.17 EPE26378.1 - 0.27 9.8 0.1 0.4 9.3 0.1 1.2 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family FAD_binding_4 PF01565.23 EPE26379.1 - 2.5e-15 56.4 0.0 4.1e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.25 EPE26380.1 - 2.1e-20 73.0 0.3 2.7e-20 72.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26380.1 - 4.9e-14 52.4 0.2 8.2e-14 51.7 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE26380.1 - 7.6e-06 26.0 0.1 1.2e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE26380.1 - 0.061 12.5 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 EPE26382.1 - 0.0002 20.5 0.2 0.0002 20.5 0.2 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain BBE PF08031.12 EPE26383.1 - 1.7e-07 31.2 3.1 1.7e-07 31.2 3.1 2.6 3 0 0 3 3 3 1 Berberine and berberine like Tyrosinase PF00264.20 EPE26384.1 - 4e-48 164.6 5.2 5.7e-48 164.1 5.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase NACHT PF05729.12 EPE26384.1 - 0.0019 18.2 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain MFS_1 PF07690.16 EPE26385.1 - 2.6e-30 105.6 39.0 3.7e-30 105.1 19.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE26385.1 - 2.1e-14 53.2 12.0 2.1e-14 53.2 12.0 2.1 1 1 2 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EPE26385.1 - 3.7e-05 22.4 4.4 6.9e-05 21.5 4.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EPE26385.1 - 0.00046 19.1 4.7 0.00046 19.1 4.7 1.9 2 1 0 2 2 2 1 MFS_1 like family DUF4360 PF14273.6 EPE26386.1 - 3.6e-25 88.9 0.4 4.1e-25 88.7 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Chitin_synth_1 PF01644.17 EPE26386.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Chitin synthase SET PF00856.28 EPE26387.1 - 2e-06 28.3 0.0 3.9e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 SET domain DnaB_2 PF07261.11 EPE26387.1 - 0.1 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Replication initiation and membrane attachment GAT PF03127.14 EPE26389.1 - 7.1e-18 64.7 3.1 9.1e-18 64.3 1.2 2.0 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 EPE26389.1 - 5.8e-05 23.0 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 VHS domain Peptidase_M28 PF04389.17 EPE26391.1 - 1.4e-34 119.5 0.0 2e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EPE26391.1 - 1.1e-13 51.0 0.5 2.1e-13 50.1 0.2 1.7 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EPE26391.1 - 0.00047 19.9 0.0 0.0016 18.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EPE26391.1 - 0.12 11.4 0.2 1.8 7.5 0.0 2.3 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase HEAT_EZ PF13513.6 EPE26392.1 - 2e-12 47.3 8.4 3.2e-06 27.5 0.0 8.3 9 2 1 10 10 10 1 HEAT-like repeat HEAT PF02985.22 EPE26392.1 - 2.5e-12 45.9 7.2 0.14 12.5 0.0 8.1 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.6 EPE26392.1 - 4.4e-07 30.2 8.5 0.071 13.5 0.2 6.7 3 2 3 6 6 6 2 HEAT repeats IBN_N PF03810.19 EPE26392.1 - 1.6e-06 27.9 5.6 1.3e-05 25.0 0.8 3.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.8 EPE26392.1 - 0.0002 21.0 1.1 19 4.7 0.0 5.1 1 1 2 4 4 4 1 CLASP N terminal Xpo1 PF08389.12 EPE26392.1 - 0.00078 19.5 2.0 4.3 7.4 0.0 5.6 4 1 1 5 5 5 1 Exportin 1-like protein DRIM PF07539.12 EPE26392.1 - 0.0061 14.9 3.6 2.9 6.1 1.3 4.5 2 2 2 5 5 5 1 Down-regulated in metastasis Cse1 PF08506.10 EPE26392.1 - 0.037 12.9 0.0 0.6 8.9 0.1 3.0 3 1 1 4 4 4 0 Cse1 HEAT_PBS PF03130.16 EPE26392.1 - 0.48 11.3 3.9 1.9e+02 3.2 0.1 5.2 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat HMGL-like PF00682.19 EPE26393.1 - 1e-80 271.1 0.0 1.5e-80 270.6 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EPE26393.1 - 6.3e-24 84.4 0.0 1.3e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain UCH PF00443.29 EPE26394.1 - 5.1e-47 160.5 0.0 6.7e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPE26394.1 - 3.6e-11 43.2 4.7 7.7e-10 38.9 4.7 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EPE26394.1 - 7.7e-10 38.4 0.1 1.7e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Med8 PF10232.9 EPE26394.1 - 0.043 13.4 6.1 0.23 11.0 0.1 2.3 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 Peptidase_M99 PF17033.5 EPE26394.1 - 0.091 12.2 0.5 0.16 11.4 0.5 1.4 1 0 0 1 1 1 0 Carboxypeptidase controlling helical cell shape catalytic TBK1_ULD PF18396.1 EPE26394.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF3037 PF11236.8 EPE26394.1 - 0.82 10.1 2.9 29 5.1 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3037) Thaumatin PF00314.17 EPE26395.1 - 4.9e-62 209.4 1.3 6.7e-62 208.9 1.3 1.2 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 EPE26395.1 - 0.013 14.8 0.0 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Beta-1,3-glucanase DUF2235 PF09994.9 EPE26397.1 - 1.6e-24 86.8 0.0 2.9e-11 43.3 0.0 2.0 1 1 1 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Hexokinase_1 PF00349.21 EPE26398.1 - 2.1e-73 246.4 0.0 3.4e-73 245.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EPE26398.1 - 4.9e-73 245.5 0.0 9.7e-73 244.5 0.0 1.5 1 1 0 1 1 1 1 Hexokinase UL42 PF17638.2 EPE26398.1 - 0.062 13.3 0.4 0.18 11.8 0.4 1.9 1 0 0 1 1 1 0 HCMV UL42 HSP70 PF00012.20 EPE26400.1 - 1.2e-11 43.6 0.3 3.1e-10 38.9 0.2 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EPE26400.1 - 0.025 13.4 0.1 0.13 11.1 0.0 1.9 2 0 0 2 2 2 0 MreB/Mbl protein Mem_trans PF03547.18 EPE26403.1 - 9.5e-51 172.4 1.8 1.9e-50 171.4 1.8 1.5 1 1 0 1 1 1 1 Membrane transport protein Pkinase PF00069.25 EPE26404.1 - 9.6e-53 179.2 0.0 6.1e-50 170.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE26404.1 - 5.6e-30 104.5 0.0 8.5e-29 100.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE26404.1 - 0.0065 15.8 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EPE26404.1 - 0.0073 15.3 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EPE26404.1 - 0.033 13.0 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EPE26404.1 - 0.049 12.7 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 EPE26405.1 - 5.7e-62 209.1 0.0 1.1e-61 208.2 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EPE26405.1 - 1e-18 66.7 0.0 2.1e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 EPE26405.1 - 2.6e-05 24.3 0.4 0.001 19.0 0.0 2.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Rad21_Rec8_N PF04825.13 EPE26406.1 - 6.6e-36 122.8 0.3 1.4e-35 121.8 0.3 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EPE26406.1 - 5.9e-05 22.3 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein TRP PF06011.12 EPE26407.1 - 2.8e-114 382.1 24.0 2.8e-114 382.1 24.0 1.7 2 1 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EPE26407.1 - 1.2e-35 122.9 0.1 1.8e-35 122.3 0.1 1.3 1 0 0 1 1 1 1 ML-like domain ATG27 PF09451.10 EPE26407.1 - 1.2 9.0 0.0 1.2 9.0 0.0 2.4 3 0 0 3 3 3 0 Autophagy-related protein 27 DUF4834 PF16118.5 EPE26407.1 - 6.8 7.7 14.8 19 6.3 0.5 4.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) Ank_4 PF13637.6 EPE26409.1 - 8.1e-08 32.7 0.1 0.0002 21.8 0.0 3.5 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE26409.1 - 9e-08 32.6 0.1 3.6e-07 30.7 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE26409.1 - 1.2e-07 31.4 0.7 0.073 13.7 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EPE26409.1 - 2.9e-05 24.3 0.1 0.088 13.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EPE26409.1 - 0.0088 16.3 0.5 6.2 7.3 0.0 3.6 3 1 0 3 3 3 1 Ankyrin repeats (many copies) TFIIS_C PF01096.18 EPE26410.1 - 2.6e-11 43.2 9.2 4.2e-11 42.5 0.2 2.9 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EPE26410.1 - 2.2e-07 30.6 4.3 1.2e-05 25.1 4.3 2.5 1 1 0 1 1 1 1 RNA polymerases M/15 Kd subunit Med31 PF05669.12 EPE26411.1 - 2.5e-37 126.8 1.2 2.8e-37 126.6 1.2 1.0 1 0 0 1 1 1 1 SOH1 Pal1 PF08316.11 EPE26414.1 - 2.6e-49 167.5 0.4 2.6e-49 167.5 0.4 1.9 2 0 0 2 2 2 1 Pal1 cell morphology protein Rad51 PF08423.11 EPE26415.1 - 0.76 9.0 2.5 1.4 8.1 0.0 2.4 2 1 0 2 2 2 0 Rad51 UBA_4 PF14555.6 EPE26416.1 - 2.4e-10 40.1 0.0 4.9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EPE26416.1 - 9e-07 29.0 0.0 2.3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 UBX domain DUF742 PF05331.11 EPE26416.1 - 0.0022 17.8 0.0 0.0091 15.8 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF742) Macoilin PF09726.9 EPE26416.1 - 7.2 5.0 11.1 10 4.6 11.1 1.1 1 0 0 1 1 1 0 Macoilin family Pan3_PK PF18101.1 EPE26418.1 - 2.1e-59 199.4 0.0 3.9e-59 198.6 0.0 1.5 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EPE26418.1 - 0.0076 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LSM PF01423.22 EPE26419.1 - 3.8e-16 58.5 0.0 4.8e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 EPE26419.1 - 0.003 18.1 10.0 0.0045 17.5 10.0 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Zn_clus PF00172.18 EPE26420.1 - 0.004 17.3 9.6 0.12 12.5 0.4 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PAN_1 PF00024.26 EPE26421.1 - 0.044 13.7 0.2 0.082 12.9 0.2 1.4 1 0 0 1 1 1 0 PAN domain BTB PF00651.31 EPE26422.1 - 4.6e-23 81.6 0.8 7.1e-13 48.8 0.8 3.5 4 0 0 4 4 4 2 BTB/POZ domain Ank_5 PF13857.6 EPE26422.1 - 1.1e-06 28.7 0.1 3.5e-06 27.2 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPE26422.1 - 1.4e-06 28.7 0.1 4e-06 27.3 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE26422.1 - 7.2e-06 26.5 0.1 1.6e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EPE26422.1 - 0.00023 21.5 0.2 0.0026 18.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EPE26422.1 - 0.016 15.7 0.8 0.3 11.8 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat Imm68 PF15583.6 EPE26422.1 - 0.12 12.6 1.7 0.66 10.1 1.7 2.1 1 1 0 1 1 1 0 Immunity protein 68 Palm_thioest PF02089.15 EPE26423.1 - 4.7e-78 262.4 0.0 5.6e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 EPE26423.1 - 0.027 13.8 0.0 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) zinc-ribbons_6 PF07191.12 EPE26423.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 zinc-ribbons Ribosomal_L1 PF00687.21 EPE26424.1 - 7.1e-63 212.0 3.0 7.1e-63 212.0 3.0 2.1 2 1 0 2 2 2 1 Ribosomal protein L1p/L10e family Lipase_GDSL_2 PF13472.6 EPE26425.1 - 2.4e-12 47.6 0.0 3.6e-10 40.5 0.0 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE26425.1 - 5.2e-07 29.9 0.0 9.8e-07 28.9 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GDI PF00996.18 EPE26426.1 - 2.2e-22 79.2 0.0 4.8e-21 74.8 0.0 2.1 1 1 0 1 1 1 1 GDP dissociation inhibitor Asp PF00026.23 EPE26427.1 - 4.6e-07 29.6 0.0 8.1e-07 28.8 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF2561 PF10812.8 EPE26427.1 - 0.0034 17.5 0.0 0.0057 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) DUF4366 PF14283.6 EPE26427.1 - 0.18 11.8 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3742 PF12553.8 EPE26430.1 - 0.022 14.9 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) FUSC-like PF12805.7 EPE26431.1 - 0.037 13.1 2.5 0.045 12.8 2.5 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF2207 PF09972.9 EPE26431.1 - 0.83 8.3 3.8 0.95 8.2 3.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PHD PF00628.29 EPE26432.1 - 1.2e-08 34.8 11.5 3e-08 33.4 11.5 1.8 1 0 0 1 1 1 1 PHD-finger Not3 PF04065.15 EPE26433.1 - 0.0073 15.8 1.4 0.01 15.3 0.6 1.6 1 1 1 2 2 2 2 Not1 N-terminal domain, CCR4-Not complex component DASH_Dad2 PF08654.10 EPE26433.1 - 0.011 16.2 1.4 0.41 11.1 0.1 2.5 2 1 1 3 3 3 0 DASH complex subunit Dad2 BORCS6 PF10157.9 EPE26433.1 - 0.093 13.0 1.2 0.12 12.6 0.2 1.7 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 DUF1664 PF07889.12 EPE26433.1 - 0.11 12.6 0.9 0.23 11.5 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) HSBP1 PF06825.12 EPE26433.1 - 0.14 12.0 2.0 6.3 6.7 0.0 2.9 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Fib_alpha PF08702.10 EPE26433.1 - 0.17 12.0 0.4 0.35 11.1 0.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 EPE26433.1 - 0.25 9.2 1.5 0.29 9.0 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2203 PF09969.9 EPE26433.1 - 1.6 9.5 5.1 5.8 7.7 0.6 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) M16C_assoc PF08367.11 EPE26433.1 - 5.8 6.0 6.6 0.21 10.7 0.6 1.7 2 1 0 2 2 2 0 Peptidase M16C associated Glyco_hydro_61 PF03443.14 EPE26434.1 - 3.8e-57 193.5 0.2 4.7e-57 193.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GDE_C PF06202.14 EPE26434.1 - 0.16 10.9 0.1 0.22 10.4 0.1 1.1 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Cellulase PF00150.18 EPE26435.1 - 6.9e-19 68.3 5.1 8.9e-19 68.0 5.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EPE26435.1 - 7.9e-08 31.8 0.2 1.2e-07 31.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF2255 PF10012.9 EPE26435.1 - 0.0056 16.8 0.6 0.013 15.6 0.6 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2255) Glyco_hydro_42 PF02449.15 EPE26435.1 - 0.012 14.9 0.5 0.027 13.8 0.1 1.7 2 0 0 2 2 2 0 Beta-galactosidase Lipase_GDSL_2 PF13472.6 EPE26436.1 - 2.2e-10 41.2 2.1 6.6e-10 39.7 2.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE26436.1 - 6.7e-10 39.3 0.1 1.4e-09 38.2 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CE2_N PF17996.1 EPE26436.1 - 0.04 13.9 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal zf-C2H2 PF00096.26 EPE26437.1 - 2.4e-08 34.0 13.0 0.0005 20.4 2.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPE26437.1 - 1.7e-05 25.0 10.1 4.6e-05 23.7 2.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPE26437.1 - 0.00023 21.7 12.0 0.12 13.3 1.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EPE26437.1 - 0.011 15.7 0.9 0.011 15.7 0.9 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 EPE26437.1 - 0.036 14.4 3.7 0.077 13.4 1.6 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EPE26437.1 - 0.082 13.2 0.4 0.082 13.2 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rpr2 PF04032.16 EPE26437.1 - 0.15 12.4 2.3 0.5 10.7 0.4 2.3 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn-ribbon_8 PF09723.10 EPE26437.1 - 0.55 10.4 2.8 4.1 7.6 1.0 2.3 1 1 1 2 2 2 0 Zinc ribbon domain Lactonase PF10282.9 EPE26439.1 - 1.7e-61 208.4 0.0 2e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HCMV_UL124 PF17609.2 EPE26439.1 - 0.099 12.8 0.2 0.22 11.7 0.1 1.6 1 1 0 1 1 1 0 Family of unknown function Lactonase PF10282.9 EPE26440.1 - 6.9e-16 58.4 1.2 8.4e-16 58.2 1.2 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller FAD_binding_4 PF01565.23 EPE26441.1 - 9.3e-26 90.2 5.5 1.5e-25 89.6 5.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE26441.1 - 2.5e-13 49.9 0.0 5e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like TRSP PF12500.8 EPE26441.1 - 0.036 13.9 0.1 0.57 10.1 0.0 2.2 2 0 0 2 2 2 0 TRSP domain C terminus to PRTase_2 MFS_1 PF07690.16 EPE26442.1 - 1.7e-24 86.5 47.1 2.1e-23 82.8 47.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE26442.1 - 2.7e-07 29.8 11.0 2.7e-07 29.8 11.0 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter DUF2733 PF10813.8 EPE26442.1 - 0.031 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) CUE PF02845.16 EPE26442.1 - 0.044 13.5 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 CUE domain DUF2976 PF11190.8 EPE26442.1 - 0.63 9.9 7.4 3.8 7.4 0.7 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) Ferric_reduct PF01794.19 EPE26444.1 - 4.8e-17 62.2 3.9 4.8e-17 62.2 3.9 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EPE26444.1 - 2.7e-16 60.1 0.0 6.8e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EPE26444.1 - 3.6e-11 43.1 0.0 9.3e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EPE26444.1 - 0.00015 22.3 0.9 1.4 9.6 0.0 3.3 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain RNase_PH PF01138.21 EPE26445.1 - 2.1e-21 76.8 0.0 3.4e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EPE26445.1 - 0.00034 20.6 0.0 0.00069 19.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 EI24 PF07264.11 EPE26447.1 - 0.0055 17.0 2.2 1.1 9.5 0.8 2.4 2 0 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) DUF389 PF04087.14 EPE26447.1 - 0.019 15.0 0.9 0.25 11.4 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF389) p450 PF00067.22 EPE26448.1 - 5.5e-37 127.6 0.0 3.2e-36 125.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 PheRS_DBD1 PF18552.1 EPE26448.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 PheRS DNA binding domain 1 Redoxin PF08534.10 EPE26450.1 - 3.5e-35 120.9 0.0 4e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EPE26450.1 - 4.4e-10 39.5 0.0 5.6e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.11 EPE26451.1 - 4.3e-62 207.8 8.3 5.2e-62 207.5 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 EPE26451.1 - 6.4e-05 23.5 0.6 9.4e-05 23.0 0.6 1.3 1 0 0 1 1 1 1 SnoaL-like domain A_deamin PF02137.18 EPE26452.1 - 8.5e-30 104.3 0.0 1.1e-29 104.0 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain NT-C2 PF10358.9 EPE26453.1 - 2e-34 118.4 0.0 3.4e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Transformer PF06495.11 EPE26453.1 - 6.6 6.8 12.7 14 5.7 12.7 1.6 1 0 0 1 1 1 0 Fruit fly transformer protein DGCR6 PF07324.11 EPE26454.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein XAF1_C PF18608.1 EPE26454.1 - 0.061 12.9 0.7 0.15 11.6 0.7 1.6 1 0 0 1 1 1 0 XIAP-associated factor 1 C-terminal domain Zn-ribbon_8 PF09723.10 EPE26454.1 - 0.16 12.1 1.0 18 5.6 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 EPE26454.1 - 0.16 12.2 1.9 2.9 8.2 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon Sgf11 PF08209.11 EPE26454.1 - 1.5 8.4 5.6 0.18 11.4 1.0 1.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Acetyltransf_1 PF00583.25 EPE26455.1 - 2.8e-05 24.3 0.0 5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE26455.1 - 0.00035 21.0 0.0 0.00054 20.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPE26455.1 - 0.25 11.3 0.0 0.45 10.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_A22B PF04258.13 EPE26456.1 - 2.9e-63 214.0 1.7 5.5e-63 213.2 1.7 1.4 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EPE26456.1 - 0.0016 18.0 17.3 0.019 14.4 11.8 3.0 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Pro_isomerase PF00160.21 EPE26457.1 - 6e-52 176.1 0.0 6.8e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3830 PF12903.7 EPE26457.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) ALO PF04030.14 EPE26458.1 - 1.3e-88 297.2 0.7 1.7e-88 296.8 0.7 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EPE26458.1 - 1.6e-24 86.2 0.0 3.1e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain His_Phos_1 PF00300.22 EPE26459.1 - 6.7e-35 120.5 0.9 1.5e-33 116.1 0.9 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cep57_CLD PF14073.6 EPE26460.1 - 0.016 15.2 3.7 0.028 14.5 1.1 2.0 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 DUF1465 PF07323.12 EPE26460.1 - 0.048 13.5 0.7 0.071 12.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) NACHT PF05729.12 EPE26461.1 - 2.1e-10 40.8 0.0 4.2e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 EPE26461.1 - 1.4e-06 28.5 0.1 0.031 14.6 0.0 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PGAP1 PF07819.13 EPE26461.1 - 1.5e-06 28.1 0.0 6.4e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein AAA_16 PF13191.6 EPE26461.1 - 0.00013 22.4 0.0 0.0014 19.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain TRAM PF01938.20 EPE26461.1 - 0.00037 20.4 0.3 1.6 8.8 0.0 2.8 2 0 0 2 2 2 2 TRAM domain DUF676 PF05057.14 EPE26461.1 - 0.00045 19.8 0.0 0.0013 18.3 0.0 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.6 EPE26461.1 - 0.0028 17.9 0.0 0.011 16.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain Nbas_N PF15492.6 EPE26461.1 - 0.022 14.1 0.0 0.5 9.6 0.0 2.4 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal RNA_helicase PF00910.22 EPE26461.1 - 0.03 14.7 0.0 0.098 13.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 EPE26461.1 - 0.03 13.6 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.17 EPE26461.1 - 0.08 13.0 0.1 9.7 6.2 0.0 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_33 PF13671.6 EPE26461.1 - 0.11 12.6 0.0 13 6.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EPE26461.1 - 0.13 11.5 0.0 0.97 8.6 0.0 2.3 2 1 0 2 2 2 0 NB-ARC domain WD40 PF00400.32 EPE26461.1 - 1.4 9.9 23.0 14 6.8 0.1 8.4 10 0 0 10 10 9 0 WD domain, G-beta repeat Hexokinase_2 PF03727.16 EPE26462.1 - 6.6e-67 225.4 0.0 8.6e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EPE26462.1 - 1.5e-62 211.0 0.0 2.3e-62 210.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase PHO4 PF01384.20 EPE26462.1 - 0.052 12.6 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphate transporter family Fructosamin_kin PF03881.14 EPE26463.1 - 9.3e-30 103.8 0.0 1.2e-29 103.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase DHQ_synthase PF01761.20 EPE26464.1 - 2.4e-63 213.8 0.0 3e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EPE26464.1 - 1e-05 25.4 3.2 0.00013 21.8 3.2 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 EPE26464.1 - 0.36 9.6 3.4 0.13 11.0 0.1 1.8 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase MARVEL PF01284.23 EPE26465.1 - 0.00013 22.0 2.7 0.00023 21.2 2.7 1.4 1 0 0 1 1 1 1 Membrane-associating domain Claudin_2 PF13903.6 EPE26465.1 - 0.12 12.1 2.2 0.36 10.6 0.8 2.4 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Ank_2 PF12796.7 EPE26466.1 - 6.6e-27 93.9 3.5 4e-08 33.7 0.1 6.3 2 1 4 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE26466.1 - 1.5e-22 79.6 2.6 0.011 16.3 0.0 8.0 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE26466.1 - 1.2e-18 66.9 1.4 0.0051 17.1 0.0 8.8 6 3 3 9 9 9 5 Ankyrin repeats (many copies) Ank PF00023.30 EPE26466.1 - 4.2e-12 45.9 8.3 0.05 14.1 0.0 9.7 10 1 1 11 11 10 2 Ankyrin repeat Ank_3 PF13606.6 EPE26466.1 - 4.1e-08 32.9 2.7 0.5 11.1 0.0 8.4 9 0 0 9 9 8 1 Ankyrin repeat NACHT PF05729.12 EPE26466.1 - 9.4e-08 32.2 0.1 6.8e-07 29.4 0.1 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EPE26466.1 - 5.5e-06 26.9 0.1 1.8e-05 25.2 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPE26466.1 - 1.7e-05 25.1 0.0 9e-05 22.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain NACHT_N PF17100.5 EPE26466.1 - 2.9e-05 24.0 0.3 8.3e-05 22.6 0.3 1.7 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_19 PF13245.6 EPE26466.1 - 0.035 14.4 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EPE26466.1 - 0.046 12.9 0.0 0.17 11.0 0.0 2.0 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 EPE26466.1 - 0.15 12.1 0.0 5.1 7.1 0.0 3.0 1 1 0 1 1 1 0 AAA domain Haem_degrading PF03928.14 EPE26467.1 - 1.1e-36 125.5 0.0 1.5e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Haem-degrading HET PF06985.11 EPE26469.1 - 2.6e-08 34.3 7.8 2e-06 28.2 2.5 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RNA_ligase PF09414.10 EPE26470.1 - 2.4e-12 47.5 0.1 5.4e-12 46.3 0.0 1.6 2 0 0 2 2 2 1 RNA ligase Goodbye PF17109.5 EPE26471.1 - 4e-15 56.3 0.0 1.5e-14 54.5 0.0 2.1 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain ZZ PF00569.17 EPE26471.1 - 0.003 17.3 4.1 0.0068 16.2 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type AAA_16 PF13191.6 EPE26471.1 - 0.0031 17.9 0.5 0.05 14.0 0.0 3.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 EPE26471.1 - 0.004 17.4 0.0 0.042 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EPE26471.1 - 0.006 16.9 0.0 0.025 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EPE26471.1 - 0.0078 16.1 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain DHR-2 PF06920.13 EPE26471.1 - 0.0097 14.6 0.9 0.02 13.5 0.0 1.9 2 0 0 2 2 2 1 Dock homology region 2 RNA_helicase PF00910.22 EPE26471.1 - 0.033 14.6 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 RNA helicase TPR_12 PF13424.6 EPE26471.1 - 0.037 14.3 4.3 2.8 8.3 0.7 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA PF00004.29 EPE26471.1 - 0.039 14.4 0.0 0.15 12.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_7 PF13176.6 EPE26471.1 - 0.16 12.1 0.3 2.6 8.3 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat HRXXH PF13933.6 EPE26472.1 - 1.7e-07 31.0 0.1 2.3e-05 24.1 0.1 2.2 2 0 0 2 2 2 2 Putative peptidase family Aspzincin_M35 PF14521.6 EPE26472.1 - 2.8e-05 24.7 0.4 0.00011 22.7 0.3 2.2 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 EPE26472.1 - 0.19 10.6 0.1 0.28 10.0 0.1 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family OPT PF03169.15 EPE26473.1 - 3e-170 567.9 63.6 3.5e-170 567.7 63.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4231 PF14015.6 EPE26473.1 - 6.1 7.4 8.1 22 5.6 0.6 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) DUF885 PF05960.11 EPE26474.1 - 2.3e-50 172.8 0.0 3.4e-50 172.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) 2OG-Fe_Oxy_2 PF10014.9 EPE26474.1 - 0.04 13.7 0.1 0.071 12.9 0.1 1.3 1 0 0 1 1 1 0 2OG-Fe dioxygenase SLS PF14611.6 EPE26475.1 - 2.5e-36 125.6 1.4 3.8e-36 125.0 0.5 1.8 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator MAGE PF01454.19 EPE26476.1 - 8.5e-51 172.7 0.0 1.5e-50 171.9 0.0 1.4 1 0 0 1 1 1 1 MAGE family PriA_3primeBD PF17764.1 EPE26476.1 - 0.048 13.6 0.1 2 8.4 0.0 2.3 1 1 1 2 2 2 0 3′ DNA-binding domain (3′BD) DNA_pol_phi PF04931.13 EPE26476.1 - 2.3 6.2 6.5 3.6 5.6 6.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi SF3b10 PF07189.11 EPE26477.1 - 9.9e-31 105.7 0.0 1.1e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) zf-C6H2 PF15801.5 EPE26478.1 - 7e-05 23.0 9.7 0.0003 21.0 2.7 2.8 2 0 0 2 2 2 2 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EPE26478.1 - 0.22 11.6 20.9 0.044 13.9 3.8 3.6 4 0 0 4 4 4 0 MYND finger Topoisom_I_N PF02919.15 EPE26478.1 - 0.43 10.1 3.3 0.74 9.3 3.3 1.4 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Peptidase_S8 PF00082.22 EPE26481.1 - 9e-11 41.6 0.0 5.4e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Subtilase family CorA PF01544.18 EPE26482.1 - 1.1e-12 48.0 0.0 5.3e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Phage_holin_3_6 PF07332.11 EPE26482.1 - 0.019 15.0 0.2 0.031 14.3 0.2 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2721 PF11026.8 EPE26482.1 - 0.18 11.7 2.0 0.2 11.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) HemY_N PF07219.13 EPE26482.1 - 4.1 7.7 5.9 1.9 8.7 3.2 1.9 2 0 0 2 2 2 0 HemY protein N-terminus CDH-cyt PF16010.5 EPE26485.1 - 3e-13 49.9 0.0 6e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EPE26485.1 - 5.8e-08 33.0 5.7 1.3e-07 31.8 5.7 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Peptidase_C15 PF01470.17 EPE26485.1 - 0.21 11.7 0.0 4.2 7.5 0.0 2.4 3 0 0 3 3 3 0 Pyroglutamyl peptidase DUF1270 PF06900.11 EPE26485.1 - 0.44 11.0 1.7 0.76 10.2 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) Ank_2 PF12796.7 EPE26486.1 - 7.7e-23 80.9 1.8 3.7e-12 46.6 0.5 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE26486.1 - 7.5e-19 65.9 0.5 3.5e-05 23.9 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EPE26486.1 - 4.7e-18 65.3 0.4 1.4e-11 44.7 0.5 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EPE26486.1 - 1.4e-14 53.7 4.3 0.00022 21.5 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EPE26486.1 - 1.7e-14 53.7 4.5 2.2e-08 34.2 0.4 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF3984 PF13136.6 EPE26486.1 - 0.32 10.4 4.3 0.048 13.1 0.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) DUF3328 PF11807.8 EPE26487.1 - 6.3e-43 147.1 0.2 7.1e-43 146.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Cu-oxidase_3 PF07732.15 EPE26488.1 - 7.6e-38 129.2 4.9 1.9e-37 127.9 1.2 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EPE26488.1 - 4.7e-36 123.5 3.5 1.4e-32 112.3 0.0 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EPE26488.1 - 1.3e-13 51.4 0.1 1.2e-09 38.5 0.1 2.5 2 0 0 2 2 2 2 Multicopper oxidase DUF3328 PF11807.8 EPE26489.1 - 0.15 11.8 4.8 0.24 11.1 4.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) YfhE PF14152.6 EPE26489.1 - 0.18 11.9 0.2 0.33 11.0 0.2 1.4 1 0 0 1 1 1 0 YfhE-like protein DUF4446 PF14584.6 EPE26490.1 - 0.00017 21.6 7.7 0.25 11.3 0.4 5.2 1 1 5 6 6 6 2 Protein of unknown function (DUF4446) DUF5470 PF17564.2 EPE26490.1 - 0.0036 17.5 21.2 14 5.9 0.2 9.0 4 3 5 9 9 9 1 Family of unknown function (DUF5470) DUF5363 PF17320.2 EPE26490.1 - 0.027 14.3 11.6 1.9e+02 2.0 0.0 8.9 6 3 6 12 12 12 0 Family of unknown function (DUF5363) Zein PF01559.16 EPE26490.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.5 1 1 0 1 1 1 0 Zein seed storage protein Stevor PF17410.2 EPE26490.1 - 0.18 11.3 4.5 0.43 10.1 0.6 2.6 1 1 1 2 2 2 0 Subtelomeric Variable Open Reading frame RNA_replicase_B PF03431.13 EPE26490.1 - 0.74 8.2 4.4 6.3 5.1 0.2 3.0 1 1 3 4 4 4 0 RNA replicase, beta-chain KID PF02524.14 EPE26490.1 - 1.9 8.9 4.7 6.4e+02 1.3 0.0 5.7 7 0 0 7 7 7 0 KID repeat PKK PF12474.8 EPE26490.1 - 7.2 6.7 8.1 3.2 7.9 0.8 3.1 3 1 1 4 4 4 0 Polo kinase kinase DUF3328 PF11807.8 EPE26491.1 - 1.9e-31 109.6 0.1 2.5e-31 109.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pam17 PF08566.10 EPE26492.1 - 0.026 14.4 0.0 0.035 14.0 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Dioxygenase_C PF00775.21 EPE26493.1 - 5.7e-42 143.2 0.0 7.6e-42 142.8 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EPE26493.1 - 2.3e-29 101.1 0.0 3.9e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EPE26493.1 - 0.033 14.5 0.0 0.11 12.7 0.0 1.9 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain ZirS_C PF16583.5 EPE26493.1 - 0.071 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain Big_1 PF02369.16 EPE26493.1 - 0.083 12.9 0.0 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 1) GTP_EFTU PF00009.27 EPE26494.1 - 1.8e-54 184.2 0.0 3.5e-54 183.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EPE26494.1 - 5.9e-38 129.6 0.0 1.2e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EPE26494.1 - 4.8e-13 49.3 2.3 4.8e-13 49.3 2.3 2.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EPE26494.1 - 0.00054 20.0 0.1 0.018 15.1 0.1 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.18 EPE26494.1 - 0.012 15.7 0.4 0.031 14.4 0.1 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain HET PF06985.11 EPE26495.1 - 1.3e-24 87.2 0.0 2.5e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lipase_3 PF01764.25 EPE26496.1 - 5.5e-14 52.2 0.0 1.9e-12 47.3 0.0 2.3 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EPE26496.1 - 0.00052 20.7 0.4 0.001 19.7 0.4 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE26496.1 - 0.049 12.9 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Acetyltransf_1 PF00583.25 EPE26497.1 - 9.1e-11 42.0 0.1 1.3e-10 41.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE26497.1 - 4.7e-09 36.3 0.0 6.4e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE26497.1 - 3.3e-08 33.8 0.6 4.9e-08 33.3 0.6 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_M14 PF00246.24 EPE26499.1 - 5.2e-83 279.2 0.1 6.3e-83 278.9 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EPE26499.1 - 8.1e-06 26.1 0.0 2.9e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase activation peptide Methyltransf_23 PF13489.6 EPE26500.1 - 1.3e-09 38.1 0.0 2.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE26500.1 - 7.1e-08 33.1 0.0 2e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE26500.1 - 1.2e-07 32.3 0.0 3.2e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE26500.1 - 2.6e-06 27.0 0.0 0.0002 20.8 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EPE26500.1 - 5.7e-06 27.0 0.0 2.5e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE26500.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain AMP-binding PF00501.28 EPE26502.1 - 3.3e-75 253.3 0.0 5.6e-75 252.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EPE26502.1 - 2.7e-61 207.0 0.0 2.7e-60 203.7 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.25 EPE26502.1 - 6e-55 185.7 1.3 1.1e-54 184.9 1.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26502.1 - 8.5e-43 146.6 0.8 1.4e-42 145.8 0.8 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE26502.1 - 2.1e-21 76.6 1.3 3e-17 63.1 1.1 2.5 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 EPE26502.1 - 6e-16 58.6 0.1 1.1e-07 31.6 0.0 3.0 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EPE26502.1 - 6.8e-12 45.6 0.0 1.7e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EPE26502.1 - 1.5e-09 37.3 0.1 6.6e-06 25.3 0.0 2.8 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EPE26502.1 - 8e-08 31.8 1.2 0.00011 21.5 0.1 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EPE26502.1 - 9.2e-08 32.2 0.3 2.6e-07 30.7 0.3 1.9 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EPE26502.1 - 1.2e-05 24.6 0.6 0.0048 16.0 0.1 3.0 2 1 0 2 2 2 2 RmlD substrate binding domain AMP-binding_C PF13193.6 EPE26502.1 - 3.6e-05 24.7 0.1 3.6e-05 24.7 0.1 3.4 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain DFP PF04127.15 EPE26502.1 - 0.0057 16.5 0.7 0.015 15.2 0.7 1.6 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein GDP_Man_Dehyd PF16363.5 EPE26502.1 - 0.0092 15.4 0.0 0.78 9.1 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 EPE26502.1 - 0.015 14.6 0.0 0.044 13.1 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 EPE26502.1 - 0.17 11.6 0.1 0.38 10.4 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA p450 PF00067.22 EPE26503.1 - 1.2e-32 113.2 0.0 1.6e-28 99.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Malic_M PF03949.15 EPE26504.1 - 2.8e-17 62.9 0.0 3.2e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain Glyco_hydro_18 PF00704.28 EPE26505.1 - 3.4e-53 181.4 0.9 4e-53 181.2 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EPE26505.1 - 5.3e-06 26.8 22.1 5.3e-06 26.8 22.1 2.3 2 0 0 2 2 2 1 Chitin recognition protein DNA_ligase_C PF17879.1 EPE26505.1 - 0.11 12.6 0.6 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 DNA ligase C-terminal domain Peptidase_S8 PF00082.22 EPE26506.1 - 8.3e-42 143.5 5.5 1.3e-41 142.8 5.5 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 EPE26506.1 - 2.2e-09 38.0 0.2 9.1e-09 36.0 0.1 2.1 2 0 0 2 2 2 1 Fn3-like domain PA PF02225.22 EPE26506.1 - 0.0012 18.9 0.0 0.004 17.1 0.0 2.0 1 0 0 1 1 1 1 PA domain TAFH PF07531.14 EPE26507.1 - 0.0006 19.9 1.3 0.097 12.8 0.1 3.6 2 0 0 2 2 2 1 NHR1 homology to TAF AlphaC_C PF17480.2 EPE26507.1 - 0.0024 17.8 17.9 1.7 8.8 0.7 6.8 2 1 2 5 5 5 2 AlphaC C-terminal DUF4363 PF14276.6 EPE26507.1 - 0.03 14.4 24.1 53 4.0 0.0 10.8 8 4 2 11 11 11 0 Domain of unknown function (DUF4363) DUF4382 PF14321.6 EPE26507.1 - 0.046 14.0 13.7 0.61 10.3 1.0 4.4 1 1 2 4 4 4 0 Domain of unknown function (DUF4382) Snapin_Pallidin PF14712.6 EPE26507.1 - 0.17 12.4 12.5 22 5.6 0.1 5.7 6 1 0 6 6 6 0 Snapin/Pallidin Syntaxin_2 PF14523.6 EPE26507.1 - 0.76 10.2 14.0 0.33 11.3 2.6 5.4 3 1 2 5 5 5 0 Syntaxin-like protein Exonuc_VII_S PF02609.16 EPE26507.1 - 1.3 9.2 3.5 13 5.9 0.1 4.0 4 0 0 4 4 4 0 Exonuclease VII small subunit DUF2730 PF10805.8 EPE26507.1 - 2.8 8.1 20.0 1 9.5 0.1 7.5 9 1 0 9 9 9 0 Protein of unknown function (DUF2730) BLOC1_2 PF10046.9 EPE26507.1 - 4.2 7.7 11.5 4 7.8 1.7 5.3 2 2 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Adeno_VII PF03228.14 EPE26507.1 - 5.5 7.7 7.2 1.2e+02 3.4 0.1 5.3 4 1 1 5 5 5 0 Adenoviral core protein VII DUF2203 PF09969.9 EPE26507.1 - 9.7 6.9 13.1 9.6 7.0 0.3 5.5 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) Sel1 PF08238.12 EPE26508.1 - 3.3e-45 151.5 23.3 6.4e-09 36.2 0.4 7.8 7 0 0 7 7 7 7 Sel1 repeat CBP4 PF07960.11 EPE26509.1 - 2.7e-25 88.7 0.3 4.1e-25 88.1 0.3 1.2 1 0 0 1 1 1 1 CBP4 Seryl_tRNA_N PF02403.22 EPE26509.1 - 0.096 12.9 5.5 0.16 12.2 5.5 1.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CRA PF06589.11 EPE26509.1 - 0.13 12.3 3.2 0.17 12.0 3.2 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Pkinase PF00069.25 EPE26510.1 - 6.2e-17 61.8 0.0 2.6e-16 59.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE26510.1 - 9.7e-07 28.3 0.1 1e-05 24.9 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EPE26510.1 - 0.00085 19.0 0.1 0.0014 18.2 0.1 1.3 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EPE26510.1 - 0.065 12.9 0.0 0.41 10.2 0.0 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EPE26510.1 - 0.095 12.0 0.0 0.91 8.8 0.0 2.3 3 0 0 3 3 3 0 Kinase-like LPP PF04728.13 EPE26512.1 - 0.018 15.4 1.4 0.018 15.4 1.4 1.9 1 1 1 2 2 2 0 Lipoprotein leucine-zipper HalX PF08663.10 EPE26512.1 - 0.022 15.0 1.9 0.029 14.7 1.9 1.3 1 1 0 1 1 1 0 HalX domain Phage_Mu_Gam PF07352.12 EPE26512.1 - 0.16 11.9 0.8 0.16 11.9 0.8 1.0 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein GMC_oxred_N PF00732.19 EPE26513.1 - 5.8e-35 121.1 0.0 1.5e-31 109.9 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE26513.1 - 4.7e-28 98.5 0.0 7.8e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 EPE26513.1 - 0.00017 21.0 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE26513.1 - 0.00033 20.8 0.0 0.00084 19.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE26513.1 - 0.017 14.2 0.1 0.047 12.8 0.1 1.8 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.24 EPE26513.1 - 0.018 14.7 0.5 0.026 14.1 0.5 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EPE26513.1 - 0.03 13.4 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 EPE26513.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EPE26513.1 - 0.15 11.3 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MPC PF03650.13 EPE26514.1 - 3.8e-47 159.0 0.5 5.7e-47 158.4 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers L51_S25_CI-B8 PF05047.16 EPE26515.1 - 2.6e-11 43.3 0.0 3.3e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Ferritin_2 PF13668.6 EPE26517.1 - 4.4e-14 52.9 0.0 7.3e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain CHZ PF09649.10 EPE26518.1 - 0.0025 17.2 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone domain CHZ adh_short PF00106.25 EPE26519.1 - 2.3e-25 89.2 0.0 2.2e-22 79.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26519.1 - 9.2e-18 64.7 0.0 4.3e-16 59.2 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE26519.1 - 1.3e-08 34.9 0.1 2.7e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EPE26519.1 - 0.00015 21.7 0.6 0.00024 21.0 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EPE26519.1 - 0.012 14.7 0.1 0.018 14.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 EPE26519.1 - 0.034 14.2 0.4 0.065 13.3 0.4 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 EPE26519.1 - 0.04 13.1 0.1 0.065 12.5 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UPF0051 PF01458.17 EPE26519.1 - 0.091 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (UPF0051) Epimerase PF01370.21 EPE26519.1 - 0.097 12.1 0.0 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 EPE26520.1 - 2.3e-17 63.2 0.0 4.6e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE26520.1 - 1.5e-07 31.0 0.0 2.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPE26520.1 - 0.0014 18.6 0.1 0.0024 17.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EPE26520.1 - 0.0023 16.8 1.5 0.0031 16.4 0.1 1.8 2 0 0 2 2 2 1 Fungal protein kinase DUF1996 PF09362.10 EPE26521.1 - 1.2e-78 264.4 0.9 1.7e-78 263.9 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) APH PF01636.23 EPE26521.1 - 8.4e-11 42.3 0.0 2.3e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE26521.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Oxysterol_BP PF01237.18 EPE26524.1 - 1.4e-140 468.4 0.7 2.1e-139 464.5 0.0 2.2 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.7 EPE26524.1 - 3e-18 66.2 0.4 1.7e-08 35.0 0.1 2.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE26524.1 - 4.8e-14 52.2 0.2 3.9e-07 30.2 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPE26524.1 - 7.4e-14 51.9 0.2 1.5e-08 35.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EPE26524.1 - 3.5e-13 49.3 0.6 0.0012 19.2 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EPE26524.1 - 5.7e-11 41.7 0.2 0.003 17.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.29 EPE26524.1 - 3.6e-10 40.3 0.6 7.9e-10 39.2 0.6 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EPE26524.1 - 5.3e-06 26.6 0.5 1.2e-05 25.5 0.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DZR PF12773.7 EPE26525.1 - 0.011 15.8 2.5 0.011 15.8 2.5 3.8 2 1 0 2 2 2 0 Double zinc ribbon CCDC53 PF10152.9 EPE26525.1 - 0.2 12.0 0.1 0.2 12.0 0.1 1.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex HNH_5 PF14279.6 EPE26525.1 - 1.1 9.1 5.4 3 7.8 0.0 3.1 2 1 0 2 2 2 0 HNH endonuclease Spt20 PF12090.8 EPE26525.1 - 1.3 8.6 7.1 1.9 8.0 7.1 1.2 1 0 0 1 1 1 0 Spt20 family zinc-ribbons_6 PF07191.12 EPE26525.1 - 1.7 8.7 12.1 0.67 10.0 1.1 3.4 2 2 0 2 2 2 0 zinc-ribbons CSN7a_helixI PF18392.1 EPE26525.1 - 7.3 6.6 7.7 1.2 9.1 0.3 2.5 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain TPR_12 PF13424.6 EPE26527.1 - 1.6e-07 31.5 5.9 0.23 11.7 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE26527.1 - 2.6e-05 24.4 5.6 0.014 15.6 0.0 4.5 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EPE26527.1 - 0.0043 17.5 5.9 5.4 7.6 0.0 5.8 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPE26527.1 - 0.0061 17.2 0.2 1.6 9.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EPE26527.1 - 0.016 15.8 4.2 1.9 9.3 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1320 PF07030.12 EPE26527.1 - 0.026 14.6 0.0 2.1 8.5 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1320) TPR_10 PF13374.6 EPE26527.1 - 0.029 14.3 1.5 1e+02 3.0 0.4 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPE26527.1 - 0.031 15.1 1.1 26 6.0 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Peripla_BP_4 PF13407.6 EPE26527.1 - 0.032 13.8 0.1 0.098 12.2 0.1 1.8 2 0 0 2 2 2 0 Periplasmic binding protein domain TPR_2 PF07719.17 EPE26527.1 - 1.1 9.6 12.6 1.2 9.4 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat BCD PF15461.6 EPE26528.1 - 0.0017 17.9 3.6 0.0026 17.3 3.6 1.2 1 0 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase SidE PF12252.8 EPE26528.1 - 0.15 9.6 0.0 0.22 9.0 0.0 1.2 1 0 0 1 1 1 0 Dot/Icm substrate protein Glycos_trans_3N PF02885.17 EPE26528.1 - 0.21 11.4 0.5 0.64 9.9 0.4 1.8 1 1 0 1 1 1 0 Glycosyl transferase family, helical bundle domain CoA_binding_3 PF13727.6 EPE26528.1 - 0.39 10.7 7.4 0.057 13.4 2.9 1.9 1 1 1 2 2 2 0 CoA-binding domain UPF0139 PF03669.13 EPE26528.1 - 0.58 10.1 4.4 22 5.0 0.5 3.2 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0139) G6B PF15096.6 EPE26530.1 - 0.0096 15.7 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 1 G6B family DUF3328 PF11807.8 EPE26531.1 - 6.5e-23 81.7 0.2 9.1e-23 81.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) p450 PF00067.22 EPE26532.1 - 1.2e-42 146.2 0.0 1.7e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 G-gamma PF00631.22 EPE26533.1 - 0.027 14.5 1.6 0.091 12.8 1.6 1.9 1 0 0 1 1 1 0 GGL domain NPV_P10 PF05531.12 EPE26533.1 - 0.12 12.9 0.9 0.37 11.3 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SMP_LBD PF17047.5 EPE26535.1 - 9.1e-27 93.7 0.1 1.3e-26 93.1 0.1 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 EPE26535.1 - 1.3e-19 70.4 0.0 1.2e-15 57.6 0.1 2.4 2 0 0 2 2 2 2 C2 domain HET PF06985.11 EPE26537.1 - 1.2e-25 90.6 0.1 2.2e-25 89.7 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PKHD_C PF18331.1 EPE26538.1 - 0.0091 16.0 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 PKHD-type hydroxylase C-terminal domain Glycos_transf_1 PF00534.20 EPE26539.1 - 4.2e-20 72.0 0.0 8.7e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EPE26539.1 - 2.1e-13 50.8 0.0 3.5e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EPE26539.1 - 0.024 15.0 0.0 0.057 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 zf-C2H2 PF00096.26 EPE26541.1 - 6.6e-06 26.3 14.6 4.8e-05 23.6 0.4 5.0 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EPE26541.1 - 0.017 15.4 2.0 0.38 11.1 0.4 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 EPE26541.1 - 0.57 10.9 6.5 0.35 11.5 0.3 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 EPE26541.1 - 0.63 10.6 11.2 2.2 8.9 0.3 4.2 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPE26541.1 - 2 9.5 21.5 0.36 11.8 0.2 5.4 5 1 0 5 5 5 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EPE26541.1 - 8.9 6.2 12.2 33 4.4 7.0 3.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain 4HBT_3 PF13622.6 EPE26542.1 - 5.5e-53 180.8 0.1 7e-53 180.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EPE26542.1 - 6.8e-11 42.1 0.0 0.0011 18.8 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase Dishevelled PF02377.15 EPE26543.1 - 0.074 13.5 4.7 0.22 12.0 4.7 1.9 1 1 0 1 1 1 0 Dishevelled specific domain Zn_clus PF00172.18 EPE26543.1 - 5.7 7.1 8.7 15 5.8 8.7 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EPE26545.1 - 0.099 12.8 3.7 0.21 11.8 3.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MazG_C PF18722.1 EPE26546.1 - 0.042 13.4 0.0 0.14 11.7 0.0 1.8 1 1 0 2 2 2 0 MazG C-terminal domain Pro-kuma_activ PF09286.11 EPE26547.1 - 2.6e-44 151.0 0.1 5.2e-44 150.0 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EPE26547.1 - 0.026 13.8 0.1 0.042 13.1 0.1 1.2 1 0 0 1 1 1 0 Subtilase family DUF4407 PF14362.6 EPE26548.1 - 5.4 6.3 9.3 6 6.1 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GST_N_2 PF13409.6 EPE26549.1 - 2.5e-16 59.7 0.0 4.9e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPE26549.1 - 1.3e-12 47.5 0.0 3.1e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPE26549.1 - 0.00063 19.9 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EPE26549.1 - 0.0016 18.7 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cyclin PF08613.11 EPE26550.1 - 0.12 12.8 0.1 0.16 12.3 0.1 1.2 1 0 0 1 1 1 0 Cyclin Cu_bind_like PF02298.17 EPE26551.1 - 0.0074 16.3 0.8 0.052 13.6 0.8 2.2 1 1 0 1 1 1 1 Plastocyanin-like domain QRPTase_C PF01729.19 EPE26552.1 - 1.9e-54 183.9 0.1 2.3e-54 183.7 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EPE26552.1 - 5.5e-19 68.0 0.0 2.7e-18 65.8 0.0 2.1 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.22 EPE26552.1 - 0.00071 19.4 0.1 0.0011 18.8 0.1 1.2 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase KDGP_aldolase PF07071.11 EPE26552.1 - 0.043 13.6 0.1 0.094 12.5 0.1 1.6 1 1 0 1 1 1 0 KDGP aldolase SBD_N PF07005.11 EPE26552.1 - 0.052 13.3 0.2 0.4 10.4 0.1 2.0 2 0 0 2 2 2 0 Sugar-binding N-terminal domain IGPS PF00218.21 EPE26552.1 - 0.095 11.9 0.1 0.2 10.8 0.1 1.5 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase PHB_depo_C PF06850.11 EPE26552.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 PHB de-polymerase C-terminus Methyltransf_11 PF08241.12 EPE26553.1 - 1.6e-27 96.0 0.0 4.2e-16 59.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EPE26553.1 - 1.9e-26 92.6 0.0 3.4e-14 53.3 0.0 2.9 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EPE26553.1 - 4.4e-20 72.2 0.0 7e-12 45.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EPE26553.1 - 3.3e-14 52.9 0.1 7.2e-10 38.9 0.0 3.2 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EPE26553.1 - 1.8e-12 47.8 0.0 2.8e-06 28.0 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 EPE26553.1 - 1.1e-10 41.2 0.0 9.9e-09 34.9 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EPE26553.1 - 4e-10 39.6 0.0 1.4e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW MTS PF05175.14 EPE26553.1 - 0.00039 20.0 0.0 0.97 9.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain NodS PF05401.11 EPE26553.1 - 0.0013 18.4 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 1 Nodulation protein S (NodS) GidB PF02527.15 EPE26553.1 - 0.0032 16.8 0.2 0.047 13.0 0.0 2.2 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G DREV PF05219.12 EPE26553.1 - 0.0045 16.1 0.0 0.012 14.7 0.0 1.7 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_32 PF13679.6 EPE26553.1 - 0.0077 16.2 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 EPE26553.1 - 0.015 14.8 0.0 2.3 7.6 0.0 3.2 3 0 0 3 3 3 0 CheR methyltransferase, SAM binding domain Methyltransf_9 PF08003.11 EPE26553.1 - 0.049 12.6 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) PrmA PF06325.13 EPE26553.1 - 0.055 12.9 0.0 6.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) HemY_N PF07219.13 EPE26555.1 - 0.12 12.6 0.6 6.3 7.1 0.1 2.7 2 0 0 2 2 2 0 HemY protein N-terminus Peroxidase_2 PF01328.17 EPE26557.1 - 7.6e-48 163.5 0.0 1e-47 163.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Dabb PF07876.12 EPE26558.1 - 5.8e-09 36.5 0.0 1.5e-08 35.2 0.0 1.6 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain DLH PF01738.18 EPE26559.1 - 4.4e-11 42.7 0.0 5.1e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EPE26559.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold SH3_1 PF00018.28 EPE26560.1 - 1.3e-09 37.5 0.1 2.3e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPE26560.1 - 1.4e-08 34.5 0.3 2.5e-08 33.6 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EPE26560.1 - 3.1e-08 33.2 0.2 2e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain YcaO PF02624.16 EPE26560.1 - 0.029 13.6 0.1 0.054 12.8 0.1 1.3 1 0 0 1 1 1 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Ank_2 PF12796.7 EPE26563.1 - 0.0069 17.0 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Acetyltransf_7 PF13508.7 EPE26563.1 - 0.0096 16.3 0.0 0.033 14.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Ank_4 PF13637.6 EPE26563.1 - 0.0098 16.5 0.0 0.038 14.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF1847 PF08901.11 EPE26563.1 - 0.028 14.0 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) BUD22 PF09073.10 EPE26563.1 - 0.65 9.3 4.6 1.1 8.5 4.6 1.3 1 0 0 1 1 1 0 BUD22 AMP-binding PF00501.28 EPE26566.1 - 3.2e-77 259.9 0.0 5.8e-74 249.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EPE26566.1 - 4.9e-56 190.3 0.0 1.4e-41 142.7 0.0 2.8 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EPE26566.1 - 3.8e-22 78.4 0.2 1.8e-12 47.4 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site ABC_tran PF00005.27 EPE26567.1 - 1.8e-42 145.1 0.0 5e-21 75.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPE26567.1 - 3.7e-26 92.4 21.9 3.7e-26 92.4 21.9 2.6 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.6 EPE26567.1 - 1.2e-06 28.6 2.3 0.029 14.2 0.0 4.4 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPE26567.1 - 1.2e-06 28.1 3.4 0.12 11.8 0.1 4.4 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EPE26567.1 - 2.1e-05 24.2 0.4 0.24 11.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EPE26567.1 - 0.00011 22.7 0.1 0.2 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 EPE26567.1 - 0.0011 18.5 0.1 0.28 10.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 EPE26567.1 - 0.0036 17.6 0.1 0.51 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EPE26567.1 - 0.0061 16.7 0.0 0.34 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EPE26567.1 - 0.0061 17.1 0.0 3.2 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EPE26567.1 - 0.0067 16.3 0.2 5 7.0 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EPE26567.1 - 0.04 14.0 0.3 12 6.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 EPE26567.1 - 0.05 13.3 0.1 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain UPF0047 PF01894.17 EPE26567.1 - 0.063 13.4 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 AAA_23 PF13476.6 EPE26567.1 - 0.11 13.0 0.8 11 6.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EPE26567.1 - 0.18 11.9 0.2 0.62 10.1 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain 3Beta_HSD PF01073.19 EPE26568.1 - 4.2e-11 42.4 0.1 9.7e-11 41.2 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EPE26568.1 - 1.2e-08 34.4 0.1 5.7e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EPE26568.1 - 2.3e-08 34.1 0.0 4.5e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE26568.1 - 7.4e-08 32.1 0.1 2.6e-07 30.3 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPE26568.1 - 4.9e-07 29.5 0.3 1.9e-06 27.6 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EPE26568.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 EPE26568.1 - 0.028 14.3 0.4 8.1 6.3 0.0 3.1 3 0 0 3 3 3 0 KR domain Polysacc_synt_2 PF02719.15 EPE26568.1 - 0.043 13.0 0.1 0.075 12.2 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Polysacc_lyase PF14099.6 EPE26568.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide lyase Fungal_trans_2 PF11951.8 EPE26569.1 - 0.00025 20.0 0.1 0.00034 19.6 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MmgE_PrpD PF03972.14 EPE26570.1 - 1.8e-151 504.6 0.0 2.3e-151 504.3 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family EAF PF09816.9 EPE26571.1 - 3.6e-22 78.6 0.4 3.6e-22 78.6 0.4 2.1 2 1 0 2 2 2 1 RNA polymerase II transcription elongation factor PAXIP1_C PF15364.6 EPE26571.1 - 0.0089 16.3 5.5 0.0089 16.3 5.5 2.6 2 1 0 2 2 2 1 PAXIP1-associated-protein-1 C term PTIP binding protein Plk4_PB1 PF18190.1 EPE26571.1 - 0.14 12.4 0.6 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 1 MEA1 PF06910.11 EPE26571.1 - 8.6 7.0 12.8 3.6 8.2 3.2 2.6 2 0 0 2 2 2 0 Male enhanced antigen 1 (MEA1) Cellulase PF00150.18 EPE26572.1 - 3.6e-50 171.0 1.1 4.3e-50 170.7 1.1 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pyr_redox_3 PF13738.6 EPE26574.1 - 1.1e-16 61.0 0.0 2e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EPE26574.1 - 1.2e-09 37.2 0.0 2.4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EPE26574.1 - 1.1e-08 34.6 0.0 6.9e-07 28.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPE26574.1 - 5e-08 32.5 0.0 3.1e-05 23.3 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EPE26574.1 - 6.7e-07 28.8 0.0 0.0029 16.9 0.0 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 EPE26574.1 - 7.7e-06 26.0 0.0 0.023 14.7 0.0 3.4 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EPE26574.1 - 0.00028 21.0 0.0 0.011 16.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE26574.1 - 0.0053 16.4 0.1 1.1 8.7 0.0 2.8 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EPE26574.1 - 0.0077 16.8 0.0 1.5 9.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 EPE26574.1 - 0.011 16.2 0.0 0.56 10.7 0.0 2.3 1 1 0 2 2 2 0 Rhodanese-like domain HI0933_like PF03486.14 EPE26574.1 - 0.043 12.5 0.0 6.5 5.3 0.0 3.2 4 0 0 4 4 4 0 HI0933-like protein GIDA PF01134.22 EPE26574.1 - 0.12 11.5 0.0 0.4 9.7 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EPE26574.1 - 0.19 10.9 0.2 1.4 8.1 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain GMC_oxred_C PF05199.13 EPE26576.1 - 4.4e-32 111.6 0.0 7.7e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EPE26576.1 - 1.7e-28 99.9 0.0 7.9e-26 91.1 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 EPE26576.1 - 7.2e-05 22.2 0.0 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE26576.1 - 0.00053 19.3 0.6 0.43 9.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE26576.1 - 0.00094 19.4 0.1 0.0027 17.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE26576.1 - 0.015 14.4 0.0 0.043 12.9 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EPE26576.1 - 0.019 13.7 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 EPE26576.1 - 0.044 12.8 0.0 0.081 12.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 EPE26576.1 - 0.048 12.9 0.1 0.074 12.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 EPE26576.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EPE26576.1 - 0.17 10.9 0.2 0.66 9.0 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.16 EPE26576.1 - 0.19 11.4 0.1 0.39 10.4 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA p450 PF00067.22 EPE26577.1 - 2.1e-49 168.5 0.0 3.3e-48 164.6 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EPE26579.1 - 3.9e-20 72.1 0.7 1.4e-16 60.5 0.2 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26579.1 - 2.7e-12 46.7 0.1 2.2e-10 40.5 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE26579.1 - 4.1e-05 23.6 0.2 0.00013 21.9 0.1 1.8 1 1 1 2 2 2 1 KR domain UCH_C PF18031.1 EPE26580.1 - 0.15 11.9 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolases CBP_BcsO PF17037.5 EPE26580.1 - 1.2 9.3 6.0 1.5 8.9 2.5 2.1 1 1 1 2 2 2 0 Cellulose biosynthesis protein BcsO IBR PF01485.21 EPE26581.1 - 2e-09 37.6 19.9 4.6e-07 30.0 5.4 4.1 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain DUF3090 PF11290.8 EPE26581.1 - 0.19 11.5 2.5 0.6 9.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) DHquinase_II PF01220.19 EPE26582.1 - 7.9e-61 203.7 0.1 9e-61 203.6 0.1 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Methyltransf_11 PF08241.12 EPE26583.1 - 4.5e-13 49.7 0.0 1.2e-12 48.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE26583.1 - 1.8e-12 47.8 0.0 6e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE26583.1 - 3.1e-09 37.5 0.0 4.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE26583.1 - 1.8e-06 27.5 0.0 7e-06 25.5 0.0 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EPE26583.1 - 5.6e-06 26.3 0.0 1.1e-05 25.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE26583.1 - 0.00019 21.3 0.0 0.00028 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NACHT_N PF17100.5 EPE26584.1 - 5.4e-21 75.5 1.6 8.1e-18 65.1 0.0 2.9 3 0 0 3 3 3 2 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 EPE26584.1 - 1.7e-12 47.8 1.1 2e-06 28.3 0.1 3.4 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE26584.1 - 1.7e-07 31.6 0.1 5e-06 27.0 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) NACHT PF05729.12 EPE26584.1 - 8.4e-07 29.1 0.4 5.2e-06 26.5 0.0 2.4 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.6 EPE26584.1 - 3.8e-05 24.1 0.0 0.00014 22.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Ank PF00023.30 EPE26584.1 - 0.00013 22.2 0.5 0.0012 19.1 0.2 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EPE26584.1 - 0.00057 20.1 0.3 0.0056 17.1 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EPE26584.1 - 0.011 16.0 0.2 0.17 12.2 0.1 2.8 1 1 1 2 2 2 0 Ankyrin repeats (many copies) KAP_NTPase PF07693.14 EPE26584.1 - 0.1 11.8 0.2 1.4 8.1 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain NAC PF01849.18 EPE26587.1 - 4.3e-23 81.0 0.2 4.3e-23 81.0 0.2 1.6 2 0 0 2 2 2 1 NAC domain AdoMet_MTase PF07757.13 EPE26588.1 - 2.5e-39 134.1 0.0 3.8e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 EPE26588.1 - 1.5e-05 25.0 0.0 2.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE26588.1 - 0.048 14.4 0.0 0.13 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 EPE26588.1 - 0.057 13.3 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L24e PF01246.20 EPE26589.1 - 2.4e-28 98.2 0.2 5.3e-28 97.0 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Abhydrolase_2 PF02230.16 EPE26590.1 - 1.8e-57 194.6 0.0 2.1e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EPE26590.1 - 3.8e-06 26.3 0.2 0.0014 18.0 0.0 3.0 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EPE26590.1 - 6.8e-05 22.4 0.5 0.0004 19.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 EPE26590.1 - 0.00025 20.8 0.0 0.0028 17.4 0.0 2.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EPE26590.1 - 0.00079 20.1 0.0 0.0012 19.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EPE26590.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EPE26590.1 - 0.0026 17.6 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF1581 PF07619.11 EPE26590.1 - 0.026 14.7 0.1 0.046 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1581) Abhydro_lipase PF04083.16 EPE26590.1 - 0.037 13.6 0.1 0.75 9.4 0.0 2.3 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF2920 PF11144.8 EPE26590.1 - 0.14 11.3 0.0 6.3 5.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Lipase_3 PF01764.25 EPE26590.1 - 0.19 11.6 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) IMD PF08397.11 EPE26591.1 - 0.00051 19.5 1.1 0.003 17.0 0.3 2.0 2 0 0 2 2 2 1 IRSp53/MIM homology domain Seryl_tRNA_N PF02403.22 EPE26591.1 - 0.091 13.0 0.1 0.36 11.1 0.2 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1687 PF07955.11 EPE26593.1 - 3.1e-34 118.2 0.4 4.1e-34 117.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Ribophorin_II PF05817.14 EPE26593.1 - 0.078 11.5 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II RRM_1 PF00076.22 EPE26594.1 - 6.3e-06 25.9 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GST_N PF02798.20 EPE26596.1 - 3.2e-13 49.8 0.0 5.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPE26596.1 - 6.5e-12 45.6 0.0 1.4e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPE26596.1 - 4.7e-11 42.9 0.0 8.8e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EPE26596.1 - 6.6e-08 32.7 0.1 1e-07 32.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPE26596.1 - 9.3e-06 25.8 0.4 1.6e-05 25.0 0.4 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPE26596.1 - 0.00067 19.6 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F-box PF00646.33 EPE26597.1 - 5e-08 32.6 0.0 1.5e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPE26597.1 - 2.2e-07 30.7 0.4 6.8e-07 29.1 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 EPE26597.1 - 0.021 14.7 0.0 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 F-box Zn_clus PF00172.18 EPE26598.1 - 4.3e-09 36.3 7.1 6.6e-09 35.7 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mpv17_PMP22 PF04117.12 EPE26599.1 - 4.5e-14 52.4 0.4 4.5e-14 52.4 0.4 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family Serine_protease PF18405.1 EPE26599.1 - 0.041 13.0 0.1 0.057 12.6 0.1 1.2 1 0 0 1 1 1 0 Gammaproteobacterial serine protease Med3 PF11593.8 EPE26600.1 - 0.017 14.3 0.6 0.023 13.9 0.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mucin PF01456.17 EPE26600.1 - 0.05 13.6 19.4 0.078 13.0 19.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Zn_clus PF00172.18 EPE26601.1 - 0.0082 16.2 14.1 0.014 15.5 14.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EccE PF11203.8 EPE26601.1 - 0.1 12.9 0.0 0.45 10.9 0.0 2.1 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE MFS_1 PF07690.16 EPE26602.1 - 1.5e-40 139.2 46.0 1.5e-40 139.2 46.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE26602.1 - 4e-14 52.0 15.0 4e-14 52.0 15.0 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2919 PF11143.8 EPE26602.1 - 0.072 13.4 4.5 0.17 12.2 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2919) DUF3918 PF13056.6 EPE26602.1 - 0.13 11.9 4.1 0.53 9.9 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) OATP PF03137.20 EPE26602.1 - 0.27 9.5 16.5 0.044 12.1 3.7 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Thr_synth_N PF14821.6 EPE26603.1 - 6.4e-30 103.2 0.0 1.5e-29 102.0 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 EPE26603.1 - 2.8e-17 63.1 0.0 2e-16 60.3 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CDH-cyt PF16010.5 EPE26604.1 - 5.2e-50 169.7 7.0 6e-50 169.4 7.0 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 EPE26604.1 - 0.013 15.8 0.2 0.019 15.1 0.2 1.4 1 0 0 1 1 1 0 DOMON domain DUF1996 PF09362.10 EPE26605.1 - 8.3e-71 238.7 0.9 1.1e-70 238.3 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Smg4_UPF3 PF03467.15 EPE26606.1 - 1.7e-43 148.7 0.9 4.8e-43 147.2 0.0 2.3 2 0 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.22 EPE26606.1 - 9.8e-06 25.3 0.0 9.3e-05 22.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) mIF3 PF14877.6 EPE26606.1 - 0.45 10.2 3.7 0.87 9.2 3.7 1.4 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Metallophos PF00149.28 EPE26607.1 - 1.7e-33 116.9 0.0 5.1e-29 102.2 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EPE26607.1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Metallophos_2 PF12850.7 EPE26607.1 - 0.066 13.4 0.0 0.21 11.7 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Putative_PNPOx PF01243.20 EPE26608.1 - 0.0017 18.5 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase YscO PF07321.12 EPE26609.1 - 8.9e-06 25.7 4.3 1.2e-05 25.3 4.3 1.1 1 0 0 1 1 1 1 Type III secretion protein YscO CENP-Q PF13094.6 EPE26609.1 - 0.00014 22.2 2.6 0.00019 21.7 2.6 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit zf-C4H2 PF10146.9 EPE26609.1 - 0.00024 21.5 2.4 0.00033 21.0 2.4 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein APG6_N PF17675.1 EPE26609.1 - 0.0017 18.9 6.0 0.0024 18.4 6.0 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region LCD1 PF09798.9 EPE26609.1 - 0.0034 16.0 2.6 0.0043 15.7 2.6 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein UPF0242 PF06785.11 EPE26609.1 - 0.011 15.8 5.2 0.016 15.3 5.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PI3K_P85_iSH2 PF16454.5 EPE26609.1 - 0.013 15.1 5.7 0.019 14.5 5.7 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4515 PF14988.6 EPE26609.1 - 0.02 14.7 8.9 0.029 14.2 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) RAP1 PF07218.11 EPE26609.1 - 0.027 12.8 4.1 0.028 12.7 4.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Golgin_A5 PF09787.9 EPE26609.1 - 0.051 13.0 5.0 0.062 12.8 5.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 GAS PF13851.6 EPE26609.1 - 0.13 11.6 11.5 0.19 11.1 11.5 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 EPE26609.1 - 0.18 11.6 10.1 0.3 10.9 9.0 1.9 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.9 EPE26609.1 - 0.23 10.5 5.8 0.3 10.1 5.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 EPE26609.1 - 0.41 9.2 4.2 0.53 8.8 4.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4140 PF13600.6 EPE26609.1 - 0.89 10.0 7.5 1.1 9.7 0.7 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Macoilin PF09726.9 EPE26609.1 - 0.95 7.9 14.4 1.2 7.6 14.4 1.1 1 0 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 EPE26609.1 - 1.1 7.1 3.1 1.4 6.7 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 EPE26609.1 - 3.7 7.6 16.6 5.7 7.0 16.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 EPE26609.1 - 8 7.0 14.8 34 5.0 14.5 2.1 1 1 0 1 1 1 0 Cell division protein ZapB DUF3300 PF11737.8 EPE26610.1 - 0.056 13.0 0.3 0.056 13.0 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3300) GAS PF13851.6 EPE26610.1 - 0.59 9.5 28.1 3.3 7.0 27.2 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding PRKG1_interact PF15898.5 EPE26610.1 - 1.2 10.0 30.8 1.3 10.0 7.7 3.6 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain V_ATPase_I PF01496.19 EPE26610.1 - 4.8 5.0 14.3 5.5 4.8 14.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family U79_P34 PF03064.16 EPE26611.1 - 0.3 10.4 5.0 0.36 10.1 5.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2796 PF10986.8 EPE26611.1 - 0.37 10.7 4.4 0.48 10.4 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) ERK-JNK_inhib PF15002.6 EPE26611.1 - 0.37 10.4 4.0 0.47 10.1 4.0 1.1 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor Mito_fiss_reg PF05308.11 EPE26612.1 - 0.085 12.9 0.0 0.085 12.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Cyclin PF08613.11 EPE26614.1 - 1.7e-05 25.3 0.0 1.7e-05 25.3 0.0 2.6 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 EPE26614.1 - 0.018 14.8 0.1 0.038 13.7 0.1 1.6 1 1 0 1 1 1 0 Cyclin, N-terminal domain Zn_clus PF00172.18 EPE26615.1 - 2.8e-05 24.1 8.5 4.7e-05 23.4 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE26615.1 - 0.0035 16.2 0.0 0.0057 15.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PSI_integrin PF17205.3 EPE26615.1 - 0.0068 16.1 2.5 0.014 15.1 2.5 1.5 1 0 0 1 1 1 1 Integrin plexin domain Pkinase PF00069.25 EPE26616.1 - 8.5e-60 202.3 0.0 7.6e-59 199.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE26616.1 - 3.1e-27 95.5 0.5 2.9e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EPE26616.1 - 0.0012 19.5 1.8 0.0012 19.5 1.8 2.5 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 EPE26616.1 - 0.0064 15.8 0.1 0.023 14.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EPE26616.1 - 0.0094 15.9 0.1 0.22 11.4 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EPE26616.1 - 0.035 13.0 0.0 0.062 12.2 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EPE26616.1 - 0.093 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSP9_HSP12 PF04119.12 EPE26617.1 - 6.6e-24 84.1 3.0 3e-23 82.0 0.7 2.1 1 1 0 2 2 2 1 Heat shock protein 9/12 adh_short PF00106.25 EPE26618.1 - 6.4e-40 136.7 0.0 8.7e-40 136.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26618.1 - 3.9e-34 118.2 0.0 5.5e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE26618.1 - 2.5e-12 47.1 0.0 4.3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EPE26618.1 - 0.03 14.1 0.5 0.18 11.6 0.2 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Thymidylat_synt PF00303.19 EPE26620.1 - 8e-101 336.7 0.0 8.9e-101 336.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase PAP2 PF01569.21 EPE26621.1 - 8.4e-12 45.0 0.0 1.5e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily Glyco_hydro2_C5 PF18565.1 EPE26621.1 - 0.089 12.6 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 TauD PF02668.16 EPE26622.1 - 3.7e-61 207.3 0.3 4.5e-61 207.0 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 EPE26623.1 - 3.6e-32 111.7 18.5 3.6e-32 111.7 18.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EPE26623.1 - 0.0019 17.2 10.8 0.0023 16.9 2.7 2.2 2 0 0 2 2 2 2 MFS_1 like family adh_short PF00106.25 EPE26624.1 - 7.1e-24 84.3 0.0 8.7e-21 74.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26624.1 - 1.5e-15 57.4 0.0 8.8e-15 54.9 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE26624.1 - 2.8e-06 27.4 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EPE26624.1 - 0.016 14.6 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrfA PF07042.11 EPE26624.1 - 0.057 12.5 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 TrfA protein Csm1_B PF18211.1 EPE26624.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Csm1 subunit domain B Epimerase PF01370.21 EPE26624.1 - 0.15 11.5 0.0 0.25 10.7 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 EPE26625.1 - 1.3e-65 221.9 0.0 2.5e-65 221.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 SET PF00856.28 EPE26626.1 - 3.8e-11 43.7 0.0 4.6e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 SET domain Tudor_3 PF18115.1 EPE26627.1 - 2.9e-07 30.2 0.0 5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EPE26627.1 - 0.0022 18.0 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 EPE26627.1 - 0.018 14.8 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain FlxA PF14282.6 EPE26627.1 - 0.03 14.3 0.2 0.056 13.4 0.2 1.5 1 0 0 1 1 1 0 FlxA-like protein CCDC-167 PF15188.6 EPE26627.1 - 0.034 14.5 0.9 0.056 13.8 0.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Cep57_MT_bd PF06657.13 EPE26627.1 - 0.074 13.5 1.3 0.15 12.6 1.3 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 SKA1 PF07160.12 EPE26627.1 - 1.4 8.7 6.4 0.26 11.1 1.6 1.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 ABC_tran_CTD PF16326.5 EPE26627.1 - 8 6.8 8.7 2.1 8.6 5.5 1.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF572 PF04502.13 EPE26628.1 - 1.2e-71 242.0 0.0 1.4e-71 241.8 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Adeno_100 PF02438.16 EPE26629.1 - 0.078 11.1 0.2 0.11 10.6 0.2 1.1 1 0 0 1 1 1 0 Late 100kD protein DUF420 PF04238.12 EPE26629.1 - 6.4 7.1 10.7 1.4e+02 2.7 10.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF420) Tyrosinase PF00264.20 EPE26631.1 - 5.4e-49 167.5 0.2 7.1e-49 167.1 0.2 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Acetyltransf_3 PF13302.7 EPE26632.1 - 7.7e-27 94.6 0.0 9e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EPE26632.1 - 0.00036 20.2 0.0 0.00083 19.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE26632.1 - 0.0066 16.7 0.0 0.0096 16.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family WD40 PF00400.32 EPE26634.1 - 5e-07 30.3 16.5 0.024 15.5 0.2 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 EPE26634.1 - 9e-06 25.2 17.4 9e-06 25.2 17.4 1.8 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type RWD PF05773.22 EPE26634.1 - 0.00046 20.5 0.1 0.0012 19.1 0.1 1.6 1 0 0 1 1 1 1 RWD domain Integrin_b_cyt PF08725.11 EPE26634.1 - 0.041 13.6 0.2 0.11 12.3 0.2 1.7 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain UQ_con PF00179.26 EPE26635.1 - 3.4e-38 130.5 0.1 7.9e-38 129.3 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPE26635.1 - 0.022 14.5 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 EPE26635.1 - 0.11 12.8 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain TRI12 PF06609.13 EPE26636.1 - 6e-38 130.7 26.7 7.3e-38 130.4 26.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EPE26636.1 - 6e-19 68.2 48.8 6e-19 68.2 48.8 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE26636.1 - 4.7e-07 29.0 12.2 4.7e-07 29.0 12.2 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4173 PF13777.6 EPE26636.1 - 5.9 6.3 15.9 0.66 9.4 0.6 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4173) zf-C2H2 PF00096.26 EPE26637.1 - 2.1e-05 24.7 49.2 0.0046 17.3 0.1 8.8 9 1 1 10 10 10 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE26637.1 - 0.066 14.1 0.1 0.066 14.1 0.1 7.9 9 1 0 9 9 9 0 C2H2-type zinc finger zf-C2HE PF16278.5 EPE26637.1 - 0.25 11.8 14.4 0.89 10.0 0.8 3.1 2 2 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger IBR PF01485.21 EPE26637.1 - 0.32 11.3 27.4 2.7 8.3 2.7 5.4 2 2 2 5 5 5 0 IBR domain, a half RING-finger domain zf-C2H2_2 PF12756.7 EPE26637.1 - 0.34 11.3 17.5 4.1 7.8 0.9 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 EPE26637.1 - 3.3 7.4 11.6 5.6 6.7 0.1 4.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-MYND PF01753.18 EPE26638.1 - 5.7e-10 39.1 12.5 9.2e-10 38.5 12.5 1.3 1 0 0 1 1 1 1 MYND finger tRNA_U5-meth_tr PF05958.11 EPE26644.1 - 7.6e-13 48.2 0.0 6.4e-11 41.8 0.0 2.9 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 EPE26644.1 - 1.7e-06 28.0 2.0 1.9e-06 27.8 0.1 2.0 2 0 0 2 2 2 1 TRAM domain Methyltransf_15 PF09445.10 EPE26644.1 - 0.0001 21.9 0.0 0.00024 20.7 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 EPE26644.1 - 0.00089 19.9 0.0 0.0026 18.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EPE26644.1 - 0.0031 17.0 0.0 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EPE26644.1 - 0.0059 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE26644.1 - 0.092 13.4 0.0 0.25 12.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EPE26644.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 US10 PF17617.2 EPE26645.1 - 0.033 14.3 0.2 0.061 13.4 0.2 1.4 1 0 0 1 1 1 0 Viral unique short region 10 SIR2 PF02146.17 EPE26646.1 - 1.2e-26 93.7 0.0 1.3e-14 54.5 0.0 2.2 2 0 0 2 2 2 2 Sir2 family GTP_EFTU PF00009.27 EPE26647.1 - 6.2e-42 143.3 0.0 1e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EPE26647.1 - 5.8e-30 103.9 0.1 1.7e-29 102.4 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EPE26647.1 - 2.5e-06 27.8 0.1 6.2e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EPE26647.1 - 0.0024 17.9 0.1 0.014 15.5 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ran-binding PF05508.11 EPE26648.1 - 8e-112 373.3 0.1 1e-111 372.9 0.1 1.1 1 0 0 1 1 1 1 RanGTP-binding protein DUF2726 PF10881.8 EPE26648.1 - 0.071 13.0 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) MFS_1 PF07690.16 EPE26649.1 - 1.8e-15 56.7 3.5 1.8e-15 56.7 3.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 EPE26649.1 - 1e-07 31.7 4.0 2.8e-07 30.3 4.0 1.7 1 0 0 1 1 1 1 Nodulin-like GtrA PF04138.14 EPE26649.1 - 0.074 13.3 0.1 0.074 13.3 0.1 3.9 4 1 0 5 5 5 0 GtrA-like protein RecX PF02631.16 EPE26649.1 - 0.14 12.6 2.3 0.36 11.3 2.3 1.6 1 1 0 1 1 1 0 RecX family DUF4271 PF14093.6 EPE26649.1 - 0.67 9.8 11.6 3.8 7.4 2.1 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4271) WSC PF01822.19 EPE26650.1 - 2.6e-70 232.6 70.4 1.5e-20 73.1 12.4 4.6 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.11 EPE26650.1 - 6.2e-27 94.3 0.0 7e-26 90.9 0.0 2.5 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EPE26650.1 - 1.4e-23 83.0 0.0 3.5e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) GLEYA PF10528.9 EPE26650.1 - 0.032 14.7 0.4 11 6.5 0.0 3.3 3 0 0 3 3 3 0 GLEYA domain FOXP-CC PF16159.5 EPE26651.1 - 0.0067 17.0 0.5 0.044 14.4 0.5 2.4 1 1 1 2 2 2 1 FOXP coiled-coil domain DNA_binding_1 PF01035.20 EPE26652.1 - 4.2e-06 26.8 0.0 8.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Fungal_trans_2 PF11951.8 EPE26653.1 - 3.8e-05 22.7 0.0 0.00058 18.8 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE26653.1 - 0.00046 20.2 2.5 0.00046 20.2 2.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_lectin PF07938.12 EPE26654.1 - 6.1e-08 32.4 0.0 0.0028 17.1 0.0 2.2 2 0 0 2 2 2 2 Fungal fucose-specific lectin WD40 PF00400.32 EPE26654.1 - 0.00073 20.3 0.7 13 6.8 0.0 6.1 8 0 0 8 8 8 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE26654.1 - 0.00098 19.4 0.0 3.8 7.9 0.0 4.2 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EPE26654.1 - 0.012 15.5 0.0 0.21 11.6 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat bZIP_1 PF00170.21 EPE26654.1 - 0.053 13.6 3.0 0.1 12.7 3.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor eIF2A PF08662.11 EPE26654.1 - 0.18 11.7 0.0 18 5.1 0.0 2.5 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A zf-RING_4 PF14570.6 EPE26655.1 - 8.6e-20 70.3 12.1 1.4e-19 69.6 12.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EPE26655.1 - 6.4e-07 29.1 7.8 1.1e-06 28.4 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 EPE26655.1 - 9e-07 28.6 0.0 2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 EPE26655.1 - 0.00046 20.5 10.4 0.00089 19.5 10.4 1.5 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.12 EPE26655.1 - 0.0013 18.1 3.9 0.0013 18.1 3.9 3.9 4 1 1 5 5 3 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 EPE26655.1 - 0.0031 17.3 9.1 0.11 12.4 9.7 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 SET_assoc PF11767.8 EPE26655.1 - 0.032 13.9 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Baculo_IE-1 PF05290.11 EPE26655.1 - 0.054 13.4 5.7 0.11 12.4 5.7 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.6 EPE26655.1 - 0.09 12.7 10.5 0.16 12.0 10.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain FYVE PF01363.21 EPE26655.1 - 0.2 11.8 3.9 0.46 10.7 3.9 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-UDP PF14569.6 EPE26655.1 - 0.23 11.6 3.8 0.48 10.6 3.8 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger FYVE_2 PF02318.16 EPE26655.1 - 3 8.1 13.4 0.096 12.9 5.3 2.6 2 1 1 3 3 3 0 FYVE-type zinc finger zf-C3HC4 PF00097.25 EPE26655.1 - 3 7.8 11.0 5.6 6.9 11.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE26655.1 - 4 7.4 10.6 7.3 6.5 10.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE26655.1 - 5.1 7.2 7.7 5.7 7.0 6.1 1.9 1 1 1 2 2 2 0 RING-type zinc-finger Complex1_30kDa PF00329.19 EPE26656.1 - 8.6e-45 152.3 0.0 1.3e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit NPC1_N PF16414.5 EPE26657.1 - 6.5e-86 287.8 9.0 9.6e-86 287.3 9.0 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EPE26657.1 - 9.1e-81 272.1 2.3 1.4e-80 271.5 2.3 1.2 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 EPE26657.1 - 6.5e-54 181.9 6.3 6.5e-54 181.9 6.3 2.8 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EPE26657.1 - 1.3e-05 24.4 8.4 1.3e-05 24.4 8.4 2.5 2 0 0 2 2 2 2 MMPL family Folate_rec PF03024.14 EPE26657.1 - 1.7e-05 24.7 1.0 5.1e-05 23.2 1.0 1.7 1 0 0 1 1 1 1 Folate receptor family HECT PF00632.25 EPE26658.1 - 5e-76 256.1 0.0 1.3e-75 254.8 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 EPE26658.1 - 0.026 14.6 3.4 37 4.6 0.2 5.8 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat RRN3 PF05327.11 EPE26658.1 - 2.7 6.4 15.6 0.12 10.9 6.1 2.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 E1_dh PF00676.20 EPE26659.1 - 4e-89 298.5 0.0 6e-89 297.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF1771 PF08590.10 EPE26659.1 - 3.6e-07 30.5 11.0 8.7e-07 29.2 11.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.16 EPE26659.1 - 0.00032 20.3 0.0 0.0037 16.9 0.0 2.9 4 0 0 4 4 4 1 CUE domain TPP_enzyme_C PF02775.21 EPE26659.1 - 0.0019 18.0 0.0 0.013 15.3 0.0 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Smr PF01713.21 EPE26659.1 - 0.015 15.6 2.7 0.078 13.4 2.7 2.2 1 1 0 1 1 1 0 Smr domain DXP_synthase_N PF13292.6 EPE26659.1 - 0.09 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF3367 PF11847.8 EPE26660.1 - 0.14 10.0 0.6 0.24 9.2 0.4 1.3 1 1 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase adh_short PF00106.25 EPE26663.1 - 9.5e-15 54.6 0.0 3.3e-09 36.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26663.1 - 7.2e-12 45.4 0.0 2.8e-10 40.2 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE26663.1 - 6.8e-06 26.1 0.0 9.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EPE26663.1 - 0.0049 16.8 0.2 0.008 16.1 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE26663.1 - 0.027 14.0 0.1 0.042 13.3 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Cadherin_5 PF17892.1 EPE26663.1 - 0.11 12.4 0.3 0.33 10.9 0.1 1.8 2 0 0 2 2 2 0 Cadherin-like domain DUF2375 PF09558.10 EPE26663.1 - 0.21 11.6 0.0 0.54 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2375) BTB PF00651.31 EPE26664.1 - 2.6e-06 27.6 0.0 4.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain fn3_2 PF16893.5 EPE26665.1 - 1.1e-38 131.2 0.1 1.8e-38 130.5 0.1 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EPE26665.1 - 4e-24 84.3 0.6 6.2e-24 83.7 0.6 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 EPE26665.1 - 7.2e-12 45.1 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EPE26665.1 - 5.6e-11 42.7 0.0 9.4e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 EPE26665.1 - 0.00075 19.7 0.0 0.0024 18.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) fn3 PF00041.21 EPE26665.1 - 0.001 19.4 0.2 0.0088 16.4 0.2 2.4 1 1 0 1 1 1 1 Fibronectin type III domain BRCT_2 PF16589.5 EPE26665.1 - 0.0023 18.3 0.0 0.0047 17.3 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Speriolin_C PF15059.6 EPE26666.1 - 0.066 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Speriolin C-terminus eIF-1a PF01176.19 EPE26667.1 - 2e-21 75.6 0.0 2.8e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.23 EPE26668.1 - 1.4e-28 99.0 0.2 2e-28 98.6 0.2 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 EPE26668.1 - 0.00017 21.3 0.3 0.0004 20.1 0.3 1.6 1 0 0 1 1 1 1 WH2 motif Shadoo PF14999.6 EPE26668.1 - 0.034 14.3 10.1 2 8.5 6.6 2.6 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective ERCC4 PF02732.15 EPE26670.1 - 1e-19 71.2 0.0 1.9e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain DUF5056 PF16479.5 EPE26671.1 - 0.13 12.5 1.0 0.16 12.2 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) DUF5316 PF17247.2 EPE26671.1 - 2.8 8.0 7.5 1.6 8.8 1.8 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5316) CorA PF01544.18 EPE26674.1 - 1e-09 38.1 0.2 2.8e-09 36.7 0.1 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DDE_Tnp_ISL3 PF01610.17 EPE26674.1 - 0.025 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Transposase Aldedh PF00171.22 EPE26675.1 - 8.5e-121 403.7 0.0 1.1e-120 403.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1644 PF07800.12 EPE26676.1 - 0.016 15.3 1.9 0.038 14.1 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) zf-H2C2_5 PF13909.6 EPE26676.1 - 4.6 7.1 9.3 0.13 12.1 0.9 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain HhH-GPD PF00730.25 EPE26678.1 - 5.2e-10 39.7 0.0 1.1e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Ndc1_Nup PF09531.10 EPE26678.1 - 0.52 8.9 3.3 0.77 8.4 3.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GATase_6 PF13522.6 EPE26679.1 - 4.2e-16 59.3 0.0 1.3e-15 57.8 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EPE26679.1 - 1.4e-12 47.6 0.0 2.7e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EPE26679.1 - 3.3e-09 36.4 0.0 8.9e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EPE26679.1 - 0.0026 16.7 0.0 0.0047 15.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ADH_zinc_N PF00107.26 EPE26679.1 - 0.076 13.0 0.1 0.81 9.7 0.0 2.5 2 1 1 3 3 3 0 Zinc-binding dehydrogenase DNA_methylase PF00145.17 EPE26680.1 - 9.4e-34 117.2 0.0 8.6e-22 77.9 0.0 2.3 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase SPT6_acidic PF14632.6 EPE26680.1 - 3.7 8.2 9.2 5 7.8 7.4 2.2 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Ribosomal_L14e PF01929.17 EPE26681.1 - 2.1e-33 114.6 5.6 3e-33 114.1 5.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EPE26681.1 - 0.00011 22.1 0.1 0.00021 21.1 0.1 1.5 1 0 0 1 1 1 1 KOW motif Prot_ATP_ID_OB PF16450.5 EPE26681.1 - 0.079 12.9 0.1 0.2 11.6 0.0 1.8 1 1 1 2 2 2 0 Proteasomal ATPase OB C-terminal domain NAC PF01849.18 EPE26682.1 - 1.2e-22 79.6 0.1 4.6e-22 77.7 0.0 1.9 2 0 0 2 2 2 1 NAC domain SelP_N PF04592.14 EPE26682.1 - 0.5 9.7 6.3 0.83 9.0 6.3 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Myc_N PF01056.18 EPE26682.1 - 1.5 8.7 6.1 0.81 9.5 3.7 1.4 1 1 0 1 1 1 0 Myc amino-terminal region Mt_ATP-synt_D PF05873.12 EPE26683.1 - 3.6e-23 82.1 0.7 4.6e-23 81.8 0.7 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Effector_1 PF04518.12 EPE26683.1 - 0.03 13.4 0.1 0.041 13.0 0.1 1.2 1 0 0 1 1 1 0 Effector from type III secretion system 120_Rick_ant PF12574.8 EPE26683.1 - 0.034 13.3 0.2 0.063 12.5 0.2 1.4 1 1 0 1 1 1 0 120 KDa Rickettsia surface antigen DUF2408 PF10303.9 EPE26683.1 - 0.43 11.1 3.0 0.91 10.1 3.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Abhydrolase_3 PF07859.13 EPE26684.1 - 4.8e-33 114.8 0.0 6.5e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE26684.1 - 0.00017 22.3 0.0 0.00026 21.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 EPE26684.1 - 0.088 11.7 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family SRP-alpha_N PF04086.13 EPE26686.1 - 1.3e-86 291.2 0.0 1.7e-86 290.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 EPE26686.1 - 3.8e-40 137.6 0.1 7.8e-40 136.6 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Isochorismatase PF00857.20 EPE26686.1 - 2.5e-25 89.7 0.0 1e-24 87.7 0.0 2.0 2 0 0 2 2 2 1 Isochorismatase family SRP54_N PF02881.19 EPE26686.1 - 7.8e-08 32.4 0.2 3.2e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EPE26686.1 - 9.8e-08 31.3 0.0 1.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EPE26686.1 - 0.00065 19.5 0.1 0.0013 18.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EPE26686.1 - 0.0012 18.9 0.0 0.042 13.9 0.0 2.5 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EPE26686.1 - 0.01 16.2 0.0 0.32 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 EPE26686.1 - 0.011 15.5 0.1 0.056 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EPE26686.1 - 0.014 15.6 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 EPE26686.1 - 0.015 14.7 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 EPE26686.1 - 0.015 15.2 0.1 0.049 13.5 0.1 1.8 1 1 0 2 2 2 0 AAA domain cobW PF02492.19 EPE26686.1 - 0.035 13.7 0.1 0.081 12.5 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Neuropep_like PF15161.6 EPE26686.1 - 0.035 13.8 0.2 0.08 12.6 0.2 1.5 1 0 0 1 1 1 0 Neuropeptide-like NTPase_1 PF03266.15 EPE26686.1 - 0.063 13.2 0.1 0.32 10.9 0.1 2.2 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 EPE26686.1 - 0.14 12.7 0.0 0.63 10.6 0.0 2.1 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 EPE26686.1 - 0.16 12.1 0.2 0.87 9.7 0.2 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 EPE26686.1 - 0.17 12.0 0.7 2.9 7.9 0.6 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain YIF1 PF03878.15 EPE26687.1 - 3.8e-101 337.6 0.7 4.3e-101 337.4 0.7 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EPE26687.1 - 0.00012 21.8 5.8 0.00023 20.9 5.8 1.4 1 0 0 1 1 1 1 Yip1 domain NAT PF04768.13 EPE26689.1 - 5.3e-53 179.2 0.5 1.6e-52 177.6 0.4 1.8 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 EPE26689.1 - 1e-31 110.4 0.0 2.1e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 EPE26689.1 - 1.9e-30 105.8 0.0 5.7e-30 104.2 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EPE26689.1 - 0.087 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 EPE26689.1 - 0.091 13.6 0.0 0.28 12.0 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Synaptobrevin PF00957.21 EPE26690.1 - 1.3e-33 114.7 0.8 1.4e-33 114.5 0.8 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 EPE26690.1 - 0.053 14.2 0.1 0.084 13.5 0.1 1.4 1 1 0 1 1 1 0 AT-hook-containing transcription factor Glyco_hydro_76 PF03663.14 EPE26691.1 - 7.2e-163 542.3 24.3 8.3e-163 542.1 24.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EPE26691.1 - 0.0059 15.7 12.5 0.05 12.7 1.1 3.1 1 1 2 3 3 3 3 Glycosyl Hydrolase Family 88 PrpF PF04303.13 EPE26692.1 - 1.5e-101 340.1 2.7 5.8e-101 338.1 2.7 1.7 1 1 0 1 1 1 1 PrpF protein TAL_FSA PF00923.19 EPE26693.1 - 6e-46 157.1 0.6 7.4e-46 156.8 0.6 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Peptidase_S51 PF03575.17 EPE26693.1 - 0.022 14.4 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 Ferritin_2 PF13668.6 EPE26694.1 - 3.3e-43 147.2 2.5 4.4e-43 146.8 2.5 1.2 1 0 0 1 1 1 1 Ferritin-like domain MFS_1 PF07690.16 EPE26696.1 - 1.9e-34 119.2 17.8 1.9e-34 119.2 17.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE26696.1 - 1.3e-09 37.5 13.8 1.1e-08 34.4 4.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EPE26696.1 - 0.00019 20.4 5.0 0.00019 20.4 5.0 3.2 3 1 0 3 3 3 1 MFS_1 like family MFS_4 PF06779.14 EPE26696.1 - 0.00077 18.9 8.6 0.0038 16.6 3.0 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 EPE26696.1 - 0.0036 15.9 15.2 0.0072 14.9 2.3 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.13 EPE26696.1 - 0.017 13.6 2.9 0.98 7.7 1.0 2.2 1 1 1 2 2 2 0 Transmembrane secretion effector TRI12 PF06609.13 EPE26696.1 - 0.046 12.1 1.4 0.07 11.5 1.4 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF2530 PF10745.9 EPE26696.1 - 0.058 13.6 2.8 0.7 10.2 1.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Glyco_hydro_92 PF07971.12 EPE26699.1 - 1.7e-145 485.5 0.1 2.3e-145 485.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EPE26699.1 - 1e-60 205.6 0.2 1.8e-60 204.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Glyco_hydro_3_C PF01915.22 EPE26702.1 - 8.5e-49 166.3 0.0 1.7e-48 165.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE26702.1 - 6.7e-37 127.5 0.0 1.1e-36 126.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE26702.1 - 1.4e-23 82.7 0.9 2.6e-23 81.9 0.9 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar_tr PF00083.24 EPE26704.1 - 4.6e-77 259.8 27.7 5.3e-77 259.6 27.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE26704.1 - 1.1e-17 64.0 29.5 1.1e-17 64.0 29.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily CRM1_repeat_3 PF18787.1 EPE26704.1 - 0.13 12.4 0.1 19 5.5 0.2 2.5 2 0 0 2 2 2 0 CRM1 / Exportin repeat 3 MFS_1_like PF12832.7 EPE26704.1 - 5.2 5.8 26.4 0.05 12.5 5.5 2.5 3 0 0 3 3 3 0 MFS_1 like family MFS_1 PF07690.16 EPE26705.1 - 2.4e-31 109.0 38.6 2.4e-31 109.0 38.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE26705.1 - 5.1e-09 35.5 18.9 1.5e-08 34.0 18.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Adeno_E3_CR2 PF02439.15 EPE26706.1 - 0.056 13.2 1.4 0.11 12.3 1.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DAG1 PF05454.11 EPE26706.1 - 0.38 10.1 0.0 0.38 10.1 0.0 2.9 2 1 0 3 3 3 0 Dystroglycan (Dystrophin-associated glycoprotein 1) CN_hydrolase PF00795.22 EPE26708.1 - 4.4e-29 101.6 0.0 5.1e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Band_7_C PF16200.5 EPE26708.1 - 0.0066 16.5 0.0 0.15 12.1 0.0 2.9 3 0 0 3 3 3 1 C-terminal region of band_7 Glyco_hydro_76 PF03663.14 EPE26709.1 - 9.2e-156 519.0 8.6 1.2e-155 518.6 8.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_16 PF00722.21 EPE26710.1 - 2.9e-15 56.2 0.4 5.7e-15 55.2 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 EPE26711.1 - 5.2e-53 179.9 1.7 1.2e-52 178.7 1.7 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EPE26711.1 - 4e-05 23.5 0.0 0.00014 21.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EPE26711.1 - 0.0012 18.3 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Fasciclin PF02469.22 EPE26712.1 - 1e-39 135.7 2.1 2.5e-21 76.2 0.8 2.2 2 0 0 2 2 2 2 Fasciclin domain Ferritin_2 PF13668.6 EPE26713.1 - 4.6e-42 143.4 2.2 7.1e-42 142.8 2.2 1.3 1 0 0 1 1 1 1 Ferritin-like domain Gln-synt_C PF00120.24 EPE26714.1 - 2.6e-86 289.8 0.0 3.5e-86 289.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF3541 PF12060.8 EPE26714.1 - 0.12 12.0 0.0 0.64 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) adh_short_C2 PF13561.6 EPE26715.1 - 1.7e-59 201.2 0.0 2e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE26715.1 - 3.4e-42 144.1 0.1 4.1e-42 143.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE26715.1 - 1.8e-10 41.0 1.0 2.8e-10 40.4 1.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EPE26715.1 - 0.00069 19.6 0.1 0.0011 18.9 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EPE26715.1 - 0.0015 17.7 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 EPE26715.1 - 0.003 18.2 0.1 0.0055 17.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain ChuX_HutX PF06228.13 EPE26715.1 - 0.021 14.6 0.0 8.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Haem utilisation ChuX/HutX UDPG_MGDP_dh_N PF03721.14 EPE26715.1 - 0.044 13.3 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_12 PF08242.12 EPE26715.1 - 0.052 14.3 0.0 0.11 13.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.21 EPE26715.1 - 0.068 12.6 0.1 0.091 12.2 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 EPE26715.1 - 0.083 12.7 0.0 0.18 11.7 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain AMP-binding PF00501.28 EPE26716.1 - 1.5e-70 238.0 0.0 2e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE26716.1 - 0.0001 23.2 0.0 0.00039 21.3 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PHY PF00360.20 EPE26717.1 - 1.2e-26 93.2 0.0 2.6e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 EPE26717.1 - 1.1e-17 64.5 0.1 2.5e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPE26717.1 - 1.4e-15 57.5 0.0 3.6e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPE26717.1 - 1.5e-12 47.4 0.9 6.7e-12 45.3 0.8 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 EPE26717.1 - 3.3e-11 43.9 0.0 9.8e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 GAF domain PAS_2 PF08446.11 EPE26717.1 - 1.9e-09 38.2 0.0 5.2e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 EPE26717.1 - 0.00074 19.4 0.2 0.0016 18.3 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Copper-fist PF00649.18 EPE26718.1 - 2.9e-21 74.7 3.0 2.9e-21 74.7 3.0 2.3 1 1 1 2 2 2 1 Copper fist DNA binding domain VESA1_N PF12785.7 EPE26718.1 - 1.3 7.9 12.8 1.7 7.5 12.8 1.3 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 GTP_EFTU PF00009.27 EPE26719.1 - 8.1e-34 116.9 5.3 3.1e-32 111.7 5.3 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EPE26719.1 - 4.7e-27 94.2 0.7 1.3e-26 92.8 0.7 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EPE26719.1 - 1.3e-09 38.1 0.1 3.6e-09 36.7 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 EPE26719.1 - 8.2e-08 32.0 0.0 1.8e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region RsgA_GTPase PF03193.16 EPE26719.1 - 2.3e-05 24.4 2.0 0.00034 20.5 0.3 2.4 1 1 1 2 2 2 1 RsgA GTPase Arf PF00025.21 EPE26719.1 - 2.4e-05 23.9 0.0 4.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EPE26719.1 - 0.00081 18.9 0.1 0.0022 17.5 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EPE26719.1 - 0.0011 18.6 0.2 0.003 17.1 0.2 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU_D4 PF14578.6 EPE26719.1 - 0.0065 16.4 0.6 0.028 14.3 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 PduV-EutP PF10662.9 EPE26719.1 - 0.0078 16.0 0.3 0.023 14.4 0.3 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 EPE26719.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D2 PF03144.25 EPE26719.1 - 0.016 15.6 0.4 0.29 11.5 0.1 2.8 2 0 0 2 2 2 0 Elongation factor Tu domain 2 MMR_HSR1_Xtn PF16897.5 EPE26719.1 - 0.034 14.2 0.2 0.078 13.0 0.2 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Hydrolase_6 PF13344.6 EPE26719.1 - 0.074 13.2 0.0 4.3 7.5 0.0 2.8 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Dynamin_N PF00350.23 EPE26719.1 - 1.6 8.7 8.3 12 5.9 0.2 4.0 3 1 1 4 4 4 0 Dynamin family SBF2 PF12335.8 EPE26719.1 - 3.4 7.2 5.9 7 6.2 5.9 1.5 1 0 0 1 1 1 0 Myotubularin protein 2-Hacid_dh_C PF02826.19 EPE26720.1 - 3.2e-39 134.1 0.0 5.1e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPE26720.1 - 2.7e-24 85.3 0.1 3.7e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EPE26720.1 - 0.0042 17.3 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EPE26720.1 - 0.013 16.1 0.2 0.046 14.3 0.1 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 EPE26720.1 - 0.019 15.0 0.0 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 EPE26720.1 - 0.045 14.2 0.1 0.29 11.6 0.0 2.3 3 1 0 3 3 3 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EPE26720.1 - 0.061 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EPE26720.1 - 0.078 13.0 1.1 0.84 9.7 1.0 2.3 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4171 PF13775.6 EPE26720.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) BLOC1_2 PF10046.9 EPE26721.1 - 0.032 14.5 1.5 0.6 10.4 0.3 2.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Scaffolding_pro PF11418.8 EPE26721.1 - 0.086 13.4 3.9 1.2 9.7 0.0 3.4 3 0 0 3 3 3 0 Phi29 scaffolding protein XhlA PF10779.9 EPE26721.1 - 0.81 9.9 3.8 13 6.0 0.2 3.2 3 0 0 3 3 3 0 Haemolysin XhlA CENP-F_leu_zip PF10473.9 EPE26721.1 - 2.2 8.3 9.4 0.21 11.6 2.0 2.6 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 EPE26721.1 - 2.7 8.1 9.8 8.4 6.5 0.7 3.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF677 PF05055.12 EPE26723.1 - 0.1 11.5 1.0 0.49 9.2 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF677) HAUS-augmin3 PF14932.6 EPE26723.1 - 0.92 9.0 3.7 0.56 9.7 0.4 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Dynamin_N PF00350.23 EPE26724.1 - 1.7e-27 96.5 1.0 6.5e-27 94.6 0.0 2.4 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 EPE26724.1 - 1e-14 54.5 1.0 1.1e-13 51.1 0.9 2.3 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EPE26724.1 - 0.00014 22.0 0.0 0.00062 19.8 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 EPE26724.1 - 0.13 12.5 0.5 0.46 10.7 0.1 2.2 2 0 0 2 2 2 0 Dynamin GTPase effector domain DUF676 PF05057.14 EPE26725.1 - 0.018 14.6 0.1 0.032 13.7 0.1 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_16 PF13191.6 EPE26725.1 - 0.037 14.4 0.0 0.15 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain FHA PF00498.26 EPE26726.1 - 5.1e-14 52.4 0.0 9.1e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EPE26726.1 - 0.035 14.4 0.0 1 9.8 0.0 2.2 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain AHSA1 PF08327.11 EPE26728.1 - 0.028 14.7 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein Phage_holin_2_4 PF16082.5 EPE26729.1 - 0.2 11.4 1.0 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Pkinase PF00069.25 EPE26730.1 - 4.1e-21 75.5 0.0 7.9e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE26730.1 - 2.9e-11 43.2 0.0 1.2e-10 41.1 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Glyco_transf_25 PF01755.17 EPE26731.1 - 0.01 15.7 0.2 0.11 12.4 0.2 2.0 1 1 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Jag_N PF14804.6 EPE26732.1 - 2.6 8.4 16.3 24 5.3 0.1 5.3 6 0 0 6 6 6 0 Jag N-terminus MFS_1 PF07690.16 EPE26735.1 - 2.1e-36 125.6 44.6 3.1e-36 125.0 43.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EPE26735.1 - 0.0032 15.8 2.3 0.0032 15.8 2.3 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Carn_acyltransf PF00755.20 EPE26736.1 - 8.7e-109 364.8 0.0 1.7e-108 363.8 0.0 1.5 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 EPE26736.1 - 1.5e-74 250.8 0.0 5.4e-74 249.0 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EPE26736.1 - 6e-48 163.6 0.0 5.2e-47 160.5 0.0 2.1 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EPE26736.1 - 5.4e-39 134.6 0.4 9.1e-39 133.8 0.4 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE26736.1 - 7.5e-37 126.0 0.2 2.1e-36 124.5 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 EPE26736.1 - 2.1e-15 58.0 0.0 1.2e-13 52.3 0.0 2.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPE26736.1 - 1.2e-10 41.4 0.0 7e-10 39.0 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EPE26736.1 - 1.4e-09 38.4 0.0 4.7e-09 36.7 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension KR PF08659.10 EPE26736.1 - 2.2e-09 37.5 0.1 2.1e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 KR domain PP-binding PF00550.25 EPE26736.1 - 2.2e-07 31.1 0.2 4.3e-06 27.0 0.1 2.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.25 EPE26736.1 - 2.1e-05 24.1 0.4 6.6e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_12 PF08242.12 EPE26736.1 - 5.7e-05 23.8 0.2 0.00035 21.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE26736.1 - 0.14 12.8 0.1 1.1 9.9 0.0 2.7 3 0 0 3 3 2 0 Methyltransferase domain Glyco_hydro_79C PF16862.5 EPE26737.1 - 2.6e-22 79.6 0.8 6.1e-22 78.5 0.8 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Glyco_hydro_43 PF04616.14 EPE26738.1 - 4.4e-16 59.0 0.8 7.8e-16 58.2 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 BPA_C PF18040.1 EPE26738.1 - 0.15 12.0 0.1 1.9 8.5 0.0 2.2 2 0 0 2 2 2 0 beta porphyranase A C-terminal AT_hook PF02178.19 EPE26740.1 - 0.11 12.5 0.2 0.11 12.5 0.2 3.1 3 0 0 3 3 3 0 AT hook motif Bac_rhamnosid6H PF17389.2 EPE26741.1 - 6.2e-19 68.4 0.2 2.9e-18 66.2 0.2 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 EPE26741.1 - 1.3e-07 31.3 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 EPE26741.1 - 0.00058 19.8 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain GDE_C PF06202.14 EPE26741.1 - 0.0011 18.0 0.5 0.014 14.4 0.5 2.0 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Glyco_hydro_100 PF12899.7 EPE26741.1 - 0.071 11.8 0.3 0.18 10.4 0.2 1.6 1 1 1 2 2 2 0 Alkaline and neutral invertase ANAPC4_WD40 PF12894.7 EPE26742.1 - 1.4e-05 25.3 0.0 0.0026 18.0 0.0 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPE26742.1 - 0.00021 22.0 3.3 1.7 9.6 0.0 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat YL1 PF05764.13 EPE26742.1 - 0.002 18.3 6.8 0.0028 17.8 6.8 1.2 1 0 0 1 1 1 1 YL1 nuclear protein BUD22 PF09073.10 EPE26742.1 - 0.033 13.5 10.2 0.048 13.0 10.2 1.1 1 0 0 1 1 1 0 BUD22 YqfQ PF14181.6 EPE26742.1 - 0.046 13.9 2.5 0.084 13.1 2.5 1.3 1 0 0 1 1 1 0 YqfQ-like protein Nop14 PF04147.12 EPE26742.1 - 0.056 11.7 6.8 0.075 11.2 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EPE26742.1 - 0.38 9.3 7.1 0.51 8.8 7.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIF_alpha PF05793.12 EPE26742.1 - 2.3 6.7 17.7 3.5 6.1 17.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_polI_A34 PF08208.11 EPE26742.1 - 4.9 7.2 13.5 8.5 6.4 13.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CCDC106 PF15794.5 EPE26742.1 - 5.1 6.7 8.2 3.3 7.4 6.2 1.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 XAP5 PF04921.14 EPE26742.1 - 5.5 6.7 8.9 8 6.2 8.9 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF3176 PF11374.8 EPE26743.1 - 7.7e-30 103.3 0.1 2.3e-29 101.7 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) PRIMA1 PF16101.5 EPE26743.1 - 4.1 7.5 6.4 0.27 11.3 0.6 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Amidase PF01425.21 EPE26745.1 - 4.9e-105 352.1 0.0 6.5e-105 351.7 0.0 1.2 1 0 0 1 1 1 1 Amidase Oxidored_FMN PF00724.20 EPE26747.1 - 7.1e-40 137.3 0.0 1.8e-39 136.0 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Metallophos PF00149.28 EPE26749.1 - 1.1e-35 123.9 0.0 1.9e-35 123.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EPE26749.1 - 6e-17 61.8 0.0 1.1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain FAM53 PF15242.6 EPE26749.1 - 1.4 8.7 10.9 2.8 7.7 10.9 1.5 1 0 0 1 1 1 0 Family of FAM53 Syntaxin PF00804.25 EPE26750.1 - 3.9e-16 59.3 3.8 6.1e-16 58.7 3.8 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 EPE26750.1 - 6.4e-12 45.3 0.3 6.4e-12 45.3 0.3 1.8 2 0 0 2 2 2 1 SNARE domain DUF1664 PF07889.12 EPE26750.1 - 0.011 15.8 4.1 1.8 8.6 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Synaptobrevin PF00957.21 EPE26750.1 - 0.021 14.6 4.0 0.053 13.3 4.0 1.7 1 0 0 1 1 1 0 Synaptobrevin MCPsignal PF00015.21 EPE26750.1 - 0.07 12.9 4.7 0.04 13.7 1.8 1.9 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Peptidase_C101 PF16218.5 EPE26750.1 - 0.076 12.3 0.8 0.12 11.7 0.8 1.2 1 0 0 1 1 1 0 Peptidase family C101 CDP-OH_P_tran_2 PF08009.11 EPE26750.1 - 0.12 12.3 2.0 0.19 11.7 2.0 1.3 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 DUF2951 PF11166.8 EPE26750.1 - 0.36 11.1 6.0 0.088 13.0 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) FixH PF05751.11 EPE26750.1 - 9.5 6.2 6.4 29 4.7 3.0 2.2 2 0 0 2 2 2 0 FixH Ank_2 PF12796.7 EPE26751.1 - 3.8e-56 187.6 10.6 7.5e-12 45.7 0.0 6.8 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE26751.1 - 9e-44 147.3 8.9 2.7e-07 31.0 0.0 11.1 6 3 7 13 13 12 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE26751.1 - 4e-38 125.1 13.4 0.072 13.7 0.0 14.8 14 0 0 14 14 14 8 Ankyrin repeat Ank PF00023.30 EPE26751.1 - 4.7e-30 102.7 26.4 4.9e-05 23.6 0.6 13.8 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.6 EPE26751.1 - 2.4e-23 81.9 7.6 0.00039 20.7 0.1 10.0 8 1 0 9 9 9 4 Ankyrin repeats (many copies) AAA_16 PF13191.6 EPE26751.1 - 4.5e-07 30.4 0.0 1.5e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EPE26751.1 - 0.00019 21.4 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.13 EPE26751.1 - 0.00025 20.9 0.0 0.00048 19.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EPE26751.1 - 0.00089 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.6 EPE26751.1 - 0.0038 17.5 0.1 0.023 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Hydrolase_4 PF12146.8 EPE26751.1 - 0.0046 16.3 0.0 0.0089 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPE26751.1 - 0.015 15.9 0.0 0.036 14.7 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family ResIII PF04851.15 EPE26751.1 - 0.034 14.2 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA PF00004.29 EPE26751.1 - 0.041 14.3 0.0 0.33 11.4 0.0 2.6 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EPE26751.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 EPE26751.1 - 0.088 12.7 0.2 0.74 9.7 0.0 2.5 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 DUF900 PF05990.12 EPE26751.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) RNA_helicase PF00910.22 EPE26751.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 EPE26751.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase CorA PF01544.18 EPE26752.1 - 1.1e-10 41.4 0.6 2.7e-10 40.1 0.6 1.7 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AMP-binding PF00501.28 EPE26753.1 - 2.2e-81 273.6 0.0 3.7e-81 272.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EPE26753.1 - 4.2e-79 265.7 0.0 8.8e-79 264.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 EPE26753.1 - 7.1e-68 229.3 0.0 1.3e-67 228.5 0.0 1.4 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 EPE26753.1 - 4.1e-58 196.2 0.4 4.1e-58 196.2 0.4 2.7 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 EPE26753.1 - 2.5e-53 181.3 0.0 1.4e-52 178.8 0.0 2.3 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EPE26753.1 - 3.2e-46 158.3 0.0 6.4e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE26753.1 - 3.1e-36 124.0 0.0 3.2e-35 120.7 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EPE26753.1 - 8.6e-30 103.8 0.0 1.8e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein KAsynt_C_assoc PF16197.5 EPE26753.1 - 8.4e-20 71.3 0.0 3.6e-19 69.3 0.0 2.3 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 EPE26753.1 - 9.4e-19 67.7 0.0 4.5e-18 65.5 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE26753.1 - 1.5e-18 68.2 0.0 2.9e-15 57.5 0.0 4.2 4 0 0 4 4 3 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EPE26753.1 - 8.7e-18 64.5 0.0 3.5e-08 33.7 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short PF00106.25 EPE26753.1 - 3.8e-10 39.5 0.3 7.7e-09 35.3 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26753.1 - 5.6e-07 29.3 0.0 1.8e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 EPE26753.1 - 0.00075 18.9 0.1 0.0025 17.2 0.1 1.9 1 0 0 1 1 1 1 Thiolase, N-terminal domain AMP-binding_C PF13193.6 EPE26753.1 - 0.021 15.8 0.0 0.091 13.8 0.0 2.2 2 0 0 2 2 1 0 AMP-binding enzyme C-terminal domain Sacchrp_dh_NADP PF03435.18 EPE26753.1 - 0.051 13.8 0.3 0.46 10.8 0.0 2.7 3 0 0 3 3 2 0 Saccharopine dehydrogenase NADP binding domain MBOAT_2 PF13813.6 EPE26754.1 - 1.7e-15 57.1 1.5 1.7e-15 57.1 1.5 1.8 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MFS_1 PF07690.16 EPE26755.1 - 1.4e-45 155.8 81.0 7.2e-41 140.3 57.5 3.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPE26755.1 - 2.6e-18 65.8 26.3 3.6e-18 65.3 26.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPE26755.1 - 9.3e-09 34.6 18.3 9.3e-09 34.6 18.3 3.1 1 1 1 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 EPE26755.1 - 0.00013 20.5 3.9 0.00013 20.5 3.9 2.7 2 1 0 2 2 2 1 Transmembrane secretion effector Zn_clus PF00172.18 EPE26757.1 - 1.1e-05 25.4 10.4 2e-05 24.6 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE26757.1 - 0.0027 16.8 1.9 0.0051 15.9 1.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Thioesterase PF00975.20 EPE26758.1 - 2.8e-23 83.3 0.0 6.4e-22 78.8 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 EPE26758.1 - 5.1e-08 33.8 0.0 1e-07 32.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE26758.1 - 8e-08 32.2 0.1 0.00015 21.5 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold DUF2974 PF11187.8 EPE26758.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 EPE26758.1 - 0.0049 16.2 0.0 0.65 9.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EPE26758.1 - 0.023 14.5 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EPE26758.1 - 0.17 11.3 0.2 0.99 8.8 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Asp PF00026.23 EPE26759.1 - 2.7e-16 59.9 0.3 3.2e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 EPE26759.1 - 0.0023 17.7 0.0 0.0048 16.7 0.0 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 EPE26759.1 - 0.011 16.0 0.5 0.019 15.2 0.5 1.3 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal FAD_binding_3 PF01494.19 EPE26760.1 - 8.5e-28 97.6 0.0 1.4e-27 96.9 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE26760.1 - 0.00033 20.0 0.2 0.16 11.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE26760.1 - 0.0012 19.0 0.1 0.0029 17.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE26760.1 - 0.0015 17.7 0.1 0.0024 17.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EPE26760.1 - 0.0016 17.4 0.6 1.1 8.0 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 EPE26760.1 - 0.0019 17.3 0.6 0.0064 15.6 0.6 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EPE26760.1 - 0.011 15.0 0.2 0.032 13.5 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE26760.1 - 0.14 10.8 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 EPE26760.1 - 0.16 12.5 0.0 0.4 11.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.25 EPE26761.1 - 8.8e-40 136.2 0.8 1.3e-39 135.7 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26761.1 - 4.2e-29 101.7 0.6 6.3e-29 101.2 0.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EPE26761.1 - 2.4e-06 27.6 0.1 4.3e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EPE26761.1 - 2.1e-05 24.5 0.2 3.3e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE26761.1 - 0.0011 18.5 0.1 0.002 17.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPE26761.1 - 0.0018 17.9 0.2 0.0037 16.9 0.2 1.6 2 0 0 2 2 2 1 NmrA-like family Rossmann-like PF10727.9 EPE26761.1 - 0.033 14.0 0.2 0.081 12.8 0.2 1.6 1 1 0 1 1 1 0 Rossmann-like domain RmlD_sub_bind PF04321.17 EPE26761.1 - 0.05 12.7 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain MtaB PF12176.8 EPE26761.1 - 0.088 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit GGACT PF06094.12 EPE26762.1 - 1.3e-08 35.5 0.1 2.2e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Bac_rhamnosid6H PF17389.2 EPE26764.1 - 2.4e-118 395.3 0.0 3.4e-118 394.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 EPE26764.1 - 2.2e-59 200.1 0.4 4.5e-59 199.1 0.4 1.5 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 EPE26764.1 - 8.7e-28 96.3 0.0 4e-27 94.2 0.0 2.1 3 0 0 3 3 3 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 EPE26764.1 - 5.2e-17 61.4 0.0 1.9e-16 59.6 0.0 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Myosin_N PF02736.19 EPE26764.1 - 0.17 11.8 1.5 10 6.0 0.1 2.5 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain WSC PF01822.19 EPE26765.1 - 2.2e-18 66.2 10.0 4.2e-18 65.3 10.0 1.5 1 0 0 1 1 1 1 WSC domain T4SS_TraI PF16932.5 EPE26765.1 - 0.16 11.1 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer LacI PF00356.21 EPE26766.1 - 0.085 12.7 1.5 0.21 11.4 1.5 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family MFS_1 PF07690.16 EPE26767.1 - 7.1e-41 140.3 24.1 7.1e-41 140.3 24.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily SecY PF00344.20 EPE26767.1 - 0.048 12.9 4.8 0.24 10.6 0.6 2.6 1 1 0 2 2 2 0 SecY translocase IMS PF00817.20 EPE26768.1 - 4.9e-40 137.0 0.0 1.1e-39 135.8 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 EPE26768.1 - 1.4e-26 92.7 1.6 2.7e-26 91.8 1.6 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 EPE26768.1 - 4.4e-14 51.4 7.2 0.00018 20.8 0.3 3.6 3 0 0 3 3 3 3 Ubiquitin binding region BRCT_2 PF16589.5 EPE26768.1 - 2.6e-11 43.7 0.0 5.9e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_C PF11799.8 EPE26768.1 - 5.1e-11 43.3 0.0 1.3e-10 42.0 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.26 EPE26768.1 - 6.5e-07 29.6 0.0 1.8e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 EPE26768.1 - 2.3e-05 24.5 0.1 0.00013 22.0 0.0 2.5 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.7 EPE26768.1 - 0.00019 21.3 0.1 0.00068 19.5 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 EPE26768.1 - 0.00019 21.6 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain mCpol PF18182.1 EPE26768.1 - 0.0072 16.6 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 minimal CRISPR polymerase domain Cdd1 PF11731.8 EPE26768.1 - 0.034 14.4 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus DUF1805 PF08827.11 EPE26768.1 - 0.038 14.3 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) HHH_5 PF14520.6 EPE26768.1 - 0.1 13.2 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain HA2 PF04408.23 EPE26769.1 - 9.2e-22 77.4 0.1 9.2e-22 77.4 0.1 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EPE26769.1 - 1.1e-12 48.3 0.0 2.3e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EPE26769.1 - 3.2e-10 40.2 0.0 1e-09 38.6 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EPE26769.1 - 7.5e-05 22.6 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EPE26769.1 - 0.0028 17.9 0.0 0.012 15.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EPE26769.1 - 0.023 14.4 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase PF06745.13 EPE26769.1 - 0.03 13.7 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 KaiC NTNH_C PF08470.10 EPE26770.1 - 0.13 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal WD40 PF00400.32 EPE26771.1 - 1.9e-06 28.5 13.4 0.0032 18.3 0.4 5.8 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE26771.1 - 9.9e-06 25.8 4.6 0.35 11.2 0.1 4.0 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPE26771.1 - 0.015 14.0 2.0 0.62 8.6 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 LigB PF02900.18 EPE26772.1 - 1.8e-34 119.1 0.0 2.3e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short_C2 PF13561.6 EPE26773.1 - 1.3e-06 28.1 0.0 1.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE26773.1 - 4.3e-06 26.3 0.0 6.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EPE26773.1 - 0.063 12.4 0.0 0.085 11.9 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Fungal_trans_2 PF11951.8 EPE26774.1 - 1.2e-48 165.8 1.0 1.8e-48 165.3 1.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE26774.1 - 2.1e-06 27.7 9.0 2.1e-06 27.7 9.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 EPE26775.1 - 2.9e-30 106.0 0.0 3.7e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LssY_C PF14067.6 EPE26775.1 - 0.16 11.5 0.3 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 LssY C-terminus Complex1_LYR_2 PF13233.6 EPE26776.1 - 4.3e-20 72.2 0.0 5.8e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EPE26776.1 - 2.3e-10 40.4 0.1 3.5e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EPE26776.1 - 0.059 14.0 0.0 0.082 13.5 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like MTS PF05175.14 EPE26777.1 - 0.2 11.2 0.0 0.44 10.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain LSM PF01423.22 EPE26778.1 - 4e-17 61.7 0.1 5.1e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EPE26778.1 - 0.0074 16.4 0.0 0.0099 16.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Pkr1 PF08636.10 EPE26779.1 - 4.8e-29 100.3 7.4 6e-29 100.0 7.4 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Pkinase PF00069.25 EPE26780.1 - 6.4e-48 163.4 0.0 5.5e-28 98.1 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE26780.1 - 1.1e-21 77.4 0.0 1.2e-14 54.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EPE26780.1 - 0.0016 18.4 0.7 0.0051 16.8 0.4 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 EPE26780.1 - 0.025 15.3 0.0 0.11 13.3 0.0 2.2 1 1 0 1 1 1 0 Protein kinase C terminal domain NPL PF17800.1 EPE26781.1 - 3e-33 114.5 9.7 3e-33 114.5 9.7 2.8 2 2 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 EPE26781.1 - 7.8e-31 106.3 0.2 2.4e-30 104.7 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Lipoprotein_11 PF03260.13 EPE26781.1 - 0.07 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Lepidopteran low molecular weight (30 kD) lipoprotein DJ-1_PfpI PF01965.24 EPE26782.1 - 2.9e-11 43.5 0.0 3.8e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GTP_EFTU PF00009.27 EPE26783.1 - 5e-09 36.0 0.0 1.2e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EPE26783.1 - 0.18 12.1 0.8 0.85 10.0 0.8 2.1 1 1 0 1 1 1 0 AAA ATPase domain V-SNARE_C PF12352.8 EPE26784.1 - 0.065 13.5 3.2 0.52 10.6 0.3 2.6 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Methyltrn_RNA_2 PF04013.12 EPE26784.1 - 0.15 11.8 0.0 0.6 9.8 0.0 1.8 2 0 0 2 2 2 0 Putative SAM-dependent RNA methyltransferase TPR_16 PF13432.6 EPE26786.1 - 0.071 13.8 0.3 14 6.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Vezatin PF12632.7 EPE26787.1 - 1.9e-75 253.8 0.0 3.5e-75 253.0 0.0 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Vpu PF00558.19 EPE26787.1 - 0.84 9.4 0.0 0.84 9.4 0.0 2.4 3 0 0 3 3 3 0 Vpu protein Cullin PF00888.22 EPE26788.1 - 1.7e-22 79.8 0.0 3e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 EPE26788.1 - 1.3e-21 76.9 1.2 3.3e-21 75.5 1.2 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 zf-RING_2 PF13639.6 EPE26789.1 - 1.2e-10 41.6 2.8 2.2e-10 40.7 2.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EPE26789.1 - 7.1e-09 35.8 2.1 1.6e-08 34.7 2.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EPE26789.1 - 3.5e-06 26.8 5.1 1.2e-05 25.0 5.1 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EPE26789.1 - 1.1e-05 25.4 0.2 2.1e-05 24.5 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EPE26789.1 - 1.7e-05 24.6 2.4 3.1e-05 23.7 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE26789.1 - 2.7e-05 24.0 1.8 4.7e-05 23.3 1.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EPE26789.1 - 0.0001 22.3 1.7 0.0001 22.3 1.7 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EPE26789.1 - 0.0003 20.6 2.1 0.00068 19.4 2.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE26789.1 - 0.00031 20.5 1.6 0.00077 19.3 1.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EPE26789.1 - 0.0046 16.6 0.3 0.01 15.5 0.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EPE26789.1 - 0.0052 16.5 0.4 0.018 14.8 0.4 1.9 1 1 0 1 1 1 1 RING-like zinc finger FANCL_C PF11793.8 EPE26789.1 - 0.015 15.5 3.5 0.32 11.2 3.5 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 EPE26789.1 - 0.05 13.4 0.3 0.13 12.1 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EPE26789.1 - 0.17 12.1 0.6 0.42 10.8 0.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Voltage_CLC PF00654.20 EPE26790.1 - 0.19 10.9 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel Sporozoite_P67 PF05642.11 EPE26790.1 - 3.5 5.6 5.0 4.5 5.2 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen APH PF01636.23 EPE26791.1 - 2.9e-41 142.0 0.0 5.6e-41 141.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EPE26791.1 - 0.0002 20.8 0.0 0.00059 19.2 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EPE26791.1 - 0.00042 20.0 0.1 0.0012 18.5 0.0 1.7 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.11 EPE26791.1 - 0.0069 15.3 0.0 0.074 11.9 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 EPE26791.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF928 PF06051.12 EPE26791.1 - 0.038 13.9 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) WD40 PF00400.32 EPE26792.1 - 4.6e-48 160.2 26.5 1.1e-06 29.2 0.2 12.2 12 1 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE26792.1 - 2e-19 69.7 5.9 0.022 15.0 0.0 10.1 5 4 5 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EPE26792.1 - 4e-17 62.5 0.6 7.6e-17 61.6 0.6 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 EPE26792.1 - 1.7e-08 33.9 1.1 0.91 8.4 0.0 6.4 5 2 2 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EPE26792.1 - 8.1e-07 28.1 1.4 0.28 9.8 0.0 4.6 4 1 0 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EPE26792.1 - 0.02 13.7 1.5 0.43 9.3 0.2 3.4 4 1 0 4 4 4 0 Nup133 N terminal like DUF1667 PF07892.11 EPE26792.1 - 0.18 11.9 0.1 0.59 10.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) WD40_like PF17005.5 EPE26792.1 - 0.19 11.0 0.0 5.9 6.1 0.0 3.2 4 0 0 4 4 4 0 WD40-like domain U3_assoc_6 PF08640.11 EPE26793.1 - 3.2e-29 100.8 0.9 7.8e-27 93.2 0.2 2.4 2 0 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 EPE26793.1 - 0.07 12.2 0.5 0.15 11.1 0.5 1.6 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EPE26793.1 - 0.17 12.8 0.2 48 5.1 0.1 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat DHH PF01368.20 EPE26795.1 - 7.2e-05 23.0 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 DHH family VSG_B PF13206.6 EPE26795.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain DHHA1 PF02272.19 EPE26795.1 - 0.039 14.4 0.1 0.13 12.7 0.1 1.8 1 1 0 1 1 1 0 DHHA1 domain CTK3_C PF12350.8 EPE26796.1 - 0.05 13.8 1.9 0.088 13.0 1.9 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus Abhydrolase_1 PF00561.20 EPE26798.1 - 2.6e-19 69.9 0.0 4.8e-14 52.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE26798.1 - 4.7e-14 53.5 0.0 8e-14 52.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE26798.1 - 0.0032 16.8 0.0 0.32 10.2 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 EPE26798.1 - 0.056 12.1 0.0 0.31 9.7 0.0 1.9 2 0 0 2 2 2 0 Ndr family bZIP_1 PF00170.21 EPE26799.1 - 0.0069 16.5 4.4 0.0097 16.0 3.7 1.6 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPE26799.1 - 0.0074 16.3 5.0 0.0088 16.1 3.4 1.9 1 1 1 2 2 2 1 Basic region leucine zipper Ovate PF04844.13 EPE26799.1 - 0.094 12.7 0.6 0.21 11.6 0.1 1.8 2 0 0 2 2 2 0 Transcriptional repressor, ovate Chromate_transp PF02417.15 EPE26800.1 - 3.3e-56 189.8 42.9 7.2e-33 113.9 11.7 3.0 2 1 1 3 3 3 2 Chromate transporter Kinesin PF00225.23 EPE26801.1 - 1.8e-65 221.1 0.1 4.2e-56 190.3 0.0 2.3 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EPE26801.1 - 5.2e-21 75.1 0.0 1.1e-20 74.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding HHH_3 PF12836.7 EPE26801.1 - 0.00011 22.4 0.0 0.00037 20.7 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EPE26801.1 - 0.00036 21.1 0.0 0.46 11.1 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix domain HHH PF00633.23 EPE26801.1 - 0.03 14.2 0.0 13 5.8 0.0 2.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif TPR_15 PF13429.6 EPE26801.1 - 0.1 11.8 0.8 0.17 11.0 0.8 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPE26801.1 - 0.19 12.6 1.5 1.4 9.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC_tran_CTD PF16326.5 EPE26801.1 - 2.1 8.6 6.1 1.8 8.9 2.1 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain MFS_1 PF07690.16 EPE26802.1 - 1.2e-34 119.8 66.3 6.1e-26 91.2 37.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE26802.1 - 5e-08 32.2 31.1 9.1e-06 24.8 14.3 3.0 2 2 0 2 2 2 2 Sugar (and other) transporter AIM24 PF01987.17 EPE26803.1 - 1.8e-52 178.1 0.1 2.3e-52 177.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Multi_ubiq PF14452.6 EPE26803.1 - 0.15 12.3 0.1 2.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Multiubiquitin ABC_membrane PF00664.23 EPE26804.1 - 1.4e-40 139.7 9.4 1.8e-40 139.3 9.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EPE26804.1 - 3.8e-34 118.1 0.0 6.8e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EPE26804.1 - 1.6e-06 27.8 0.0 0.0007 19.1 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EPE26804.1 - 0.00056 20.2 0.1 0.0055 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPE26804.1 - 0.0006 20.2 0.2 0.0015 18.9 0.0 1.8 2 1 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.6 EPE26804.1 - 0.0032 17.3 0.0 0.035 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EPE26804.1 - 0.0043 17.1 0.1 0.12 12.5 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EPE26804.1 - 0.0049 16.6 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EPE26804.1 - 0.0055 17.1 0.0 0.062 13.7 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EPE26804.1 - 0.012 15.7 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EPE26804.1 - 0.034 14.1 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 EPE26804.1 - 0.038 13.7 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EPE26804.1 - 0.043 13.6 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 EPE26804.1 - 0.05 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 EPE26804.1 - 0.051 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EPE26804.1 - 0.082 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region MAM33 PF02330.16 EPE26806.1 - 5e-73 245.5 0.1 6.2e-73 245.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Tma16 PF11176.8 EPE26807.1 - 1.6e-51 174.0 0.4 2.1e-51 173.7 0.4 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 XPG_I PF00867.18 EPE26808.1 - 2.3e-23 82.4 0.1 5.6e-23 81.1 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EPE26808.1 - 1.6e-22 79.9 0.0 3.3e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EPE26808.1 - 0.00086 18.8 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing IBR PF01485.21 EPE26809.1 - 1.4e-22 79.6 51.5 2.2e-12 47.0 7.1 4.6 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EPE26809.1 - 1.2e-05 25.1 42.9 0.0011 18.8 6.1 4.7 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE26809.1 - 0.0065 16.8 48.3 0.015 15.6 10.0 4.2 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 EPE26809.1 - 0.012 15.4 44.4 0.081 12.8 3.4 5.0 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE26809.1 - 0.016 15.2 5.4 0.016 15.2 5.4 3.9 3 1 0 3 3 3 0 RING-type zinc-finger UN_NPL4 PF11543.8 EPE26809.1 - 0.019 15.5 0.5 0.057 13.9 0.0 2.1 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 AceK PF06315.11 EPE26809.1 - 0.1 11.1 4.0 0.15 10.5 4.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) zf-C3HC4_4 PF15227.6 EPE26809.1 - 2.4 8.4 34.5 0.37 11.0 5.0 4.5 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EPE26809.1 - 3 8.2 37.2 3.7 7.9 4.8 3.8 3 0 0 3 3 3 0 RING-H2 zinc finger domain Redoxin PF08534.10 EPE26810.1 - 6.9e-27 94.0 0.0 8.1e-27 93.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin Sortilin-Vps10 PF15902.5 EPE26811.1 - 0.00014 20.8 0.8 0.037 12.8 0.0 2.9 2 1 1 3 3 3 2 Sortilin, neurotensin receptor 3, BNR PF02012.20 EPE26811.1 - 0.0032 17.2 1.9 1.2 9.5 0.1 3.5 2 0 0 2 2 2 2 BNR/Asp-box repeat BNR_2 PF13088.6 EPE26811.1 - 0.0091 15.3 0.0 0.022 14.1 0.0 1.7 2 0 0 2 2 2 1 BNR repeat-like domain Fig1 PF12351.8 EPE26812.1 - 7.7e-57 192.3 4.1 7.7e-57 192.3 4.1 2.0 2 0 0 2 2 2 2 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EPE26812.1 - 1.9e-07 31.0 11.6 3.1e-07 30.2 11.6 1.3 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 EPE26812.1 - 0.0022 17.1 12.8 0.0048 16.0 12.8 1.6 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF898) Drc1-Sld2 PF11719.8 EPE26813.1 - 2.8e-105 353.5 24.6 3.2e-105 353.3 24.6 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein zf-C3HC4_3 PF13920.6 EPE26814.1 - 3.8e-08 33.1 6.0 5.6e-08 32.5 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE26814.1 - 2.8e-07 30.8 10.3 4.7e-07 30.0 10.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EPE26814.1 - 8.4e-06 25.6 5.4 1.4e-05 24.8 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE26814.1 - 8.2e-05 22.4 9.4 0.00014 21.7 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPE26814.1 - 0.00033 20.9 6.8 0.0009 19.5 6.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EPE26814.1 - 0.0042 16.9 4.1 0.0074 16.1 4.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 YdjO PF14169.6 EPE26814.1 - 0.025 14.3 0.8 0.25 11.1 0.0 2.5 2 0 0 2 2 2 0 Cold-inducible protein YdjO GAGA PF09237.11 EPE26814.1 - 0.059 13.2 1.7 0.43 10.4 0.0 2.8 3 0 0 3 3 3 0 GAGA factor F-box-like_2 PF13013.6 EPE26815.1 - 0.094 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain Mito_carr PF00153.27 EPE26816.1 - 1e-60 201.7 3.6 5.7e-22 77.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WSC PF01822.19 EPE26817.1 - 2.3e-11 43.7 11.4 4.3e-11 42.8 11.4 1.5 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 EPE26817.1 - 3e-05 23.3 2.6 3e-05 23.3 2.6 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF5305 PF17231.2 EPE26817.1 - 0.017 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2627 PF11118.8 EPE26817.1 - 0.019 15.6 0.1 0.037 14.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Insulin_TMD PF17870.1 EPE26817.1 - 0.077 13.1 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Gram_pos_anchor PF00746.21 EPE26817.1 - 0.19 11.7 5.0 1.4 8.9 0.3 2.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Trp_oprn_chp PF09534.10 EPE26817.1 - 4.3 7.1 13.0 0.35 10.6 6.5 2.2 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RINT1_TIP1 PF04437.13 EPE26818.1 - 6.5e-161 536.6 0.0 8.7e-161 536.2 0.0 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family CRISPR_Cse2 PF09485.10 EPE26818.1 - 0.034 14.7 0.1 0.075 13.6 0.1 1.5 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DNA_ligase_A_M PF01068.21 EPE26819.1 - 4e-50 170.3 0.1 1.6e-47 161.8 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EPE26819.1 - 3.6e-36 125.1 0.0 8.6e-36 123.9 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EPE26819.1 - 1.1e-18 67.7 0.0 1.7e-17 63.9 0.0 3.0 4 0 0 4 4 4 1 ATP dependent DNA ligase C terminal region HeLo PF14479.6 EPE26821.1 - 0.045 13.6 8.2 1.5 8.6 0.1 4.3 5 0 0 5 5 5 0 Prion-inhibition and propagation Osmo_CC PF08946.10 EPE26821.1 - 0.072 13.3 1.0 0.49 10.7 0.2 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil CorA PF01544.18 EPE26821.1 - 0.076 12.3 0.3 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein XOO_2897-deam PF14440.6 EPE26822.1 - 0.097 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Asp PF00026.23 EPE26823.1 - 6.2e-108 360.9 0.1 7.3e-108 360.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPE26823.1 - 8.4e-17 62.0 1.3 1.4e-14 54.8 1.0 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EPE26823.1 - 0.00012 22.7 0.1 1.7 9.3 0.0 3.7 2 2 1 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 EPE26823.1 - 0.0028 17.5 0.0 0.034 13.9 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EPE26823.1 - 0.0028 18.2 0.0 3.1 8.4 0.0 2.9 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease UL42 PF17638.2 EPE26825.1 - 0.007 16.3 0.8 0.007 16.3 0.8 1.1 1 0 0 1 1 1 1 HCMV UL42 Pkinase PF00069.25 EPE26827.1 - 1.3e-53 182.0 0.1 1.9e-53 181.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE26827.1 - 7.1e-24 84.5 0.3 1.8e-23 83.2 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EPE26827.1 - 0.0049 15.9 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase TMA7 PF09072.10 EPE26828.1 - 4.9e-24 84.9 20.6 5.4e-24 84.8 20.6 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 adh_short_C2 PF13561.6 EPE26829.1 - 6.6e-49 166.6 3.2 1.6e-46 158.7 3.2 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE26829.1 - 4.9e-44 150.1 1.8 6.7e-44 149.7 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE26829.1 - 2.8e-14 53.4 0.3 4.5e-14 52.7 0.3 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EPE26829.1 - 0.006 16.5 0.9 0.0082 16.0 0.9 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EPE26829.1 - 0.041 13.9 0.4 0.075 13.1 0.4 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TruB_C PF09142.11 EPE26829.1 - 0.22 11.3 1.2 0.88 9.4 0.0 2.5 2 1 1 3 3 3 0 tRNA Pseudouridine synthase II, C terminal RINGv PF12906.7 EPE26831.1 - 5.7e-06 26.3 5.3 9.8e-06 25.6 5.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EPE26831.1 - 0.0015 18.8 4.8 0.0027 18.0 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EPE26831.1 - 0.03 14.5 2.6 0.063 13.5 2.6 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain PHD_Oberon PF07227.11 EPE26831.1 - 0.064 13.1 0.5 0.11 12.4 0.5 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein HscB_4_cys PF18256.1 EPE26831.1 - 2.4 8.0 6.2 0.62 9.9 0.3 2.7 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif DUF604 PF04646.12 EPE26832.1 - 2e-11 43.8 1.1 3.5e-11 43.0 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 EPE26832.1 - 3.1e-09 36.7 0.1 7.9e-09 35.3 0.1 1.6 1 1 0 1 1 1 1 Fringe-like Meth_synt_2 PF01717.18 EPE26833.1 - 1e-11 44.7 0.0 1e-06 28.2 0.0 2.6 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EPE26833.1 - 0.031 13.8 0.1 0.088 12.3 0.0 1.7 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain Fungal_trans PF04082.18 EPE26835.1 - 1.2e-14 54.0 0.5 3.2e-14 52.6 0.5 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE26835.1 - 4.8e-08 33.0 12.1 4.8e-08 33.0 12.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 EPE26836.1 - 2.4e-56 191.1 0.0 2.9e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glycos_transf_2 PF00535.26 EPE26837.1 - 8.3e-32 110.3 0.0 1e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EPE26837.1 - 8.6e-11 42.2 0.0 1.2e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EPE26837.1 - 5.2e-05 22.9 0.0 7.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EPE26837.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 FAD_binding_4 PF01565.23 EPE26839.1 - 7.3e-26 90.6 1.8 1.5e-25 89.5 1.0 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EPE26839.1 - 0.01 15.9 1.3 0.021 14.9 0.8 1.9 2 0 0 2 2 2 0 Berberine and berberine like TPR_19 PF14559.6 EPE26840.1 - 1.2e-06 28.9 1.1 0.0061 17.0 0.5 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPE26840.1 - 0.00089 19.2 3.2 0.87 9.9 0.5 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EPE26840.1 - 0.014 15.1 1.5 0.85 9.6 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPE26840.1 - 0.038 14.8 2.3 6.6 7.8 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EPE26840.1 - 0.04 14.1 1.7 14 5.9 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPE26840.1 - 0.046 14.0 4.6 0.45 10.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EPE26840.1 - 0.061 13.6 0.5 41 4.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat GalKase_gal_bdg PF10509.9 EPE26841.1 - 1.9e-20 72.1 0.0 3.6e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EPE26841.1 - 1.5e-14 54.0 3.8 4.2e-14 52.5 2.9 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EPE26841.1 - 4.6e-14 52.5 0.0 1.5e-13 50.9 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal TPP_enzyme_N PF02776.18 EPE26842.1 - 1.5e-52 177.7 0.1 4.9e-52 176.0 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EPE26842.1 - 3.7e-49 166.4 0.1 1.8e-47 160.9 0.1 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EPE26842.1 - 1.5e-39 134.9 0.9 4.1e-39 133.5 0.4 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF2207 PF09972.9 EPE26843.1 - 0.17 10.6 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF724 PF05266.14 EPE26844.1 - 0.00019 21.3 0.5 0.00019 21.3 0.5 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF724) ATP-synt_F6 PF05511.11 EPE26844.1 - 0.065 13.7 0.4 0.16 12.4 0.4 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 adh_short PF00106.25 EPE26845.1 - 1.3e-44 152.0 0.0 1.7e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26845.1 - 1.3e-37 129.6 0.0 2.7e-37 128.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE26845.1 - 2.7e-16 60.0 0.0 3.7e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE26845.1 - 1e-05 24.8 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EPE26845.1 - 0.0012 18.4 0.0 0.0022 17.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_2 PF07992.14 EPE26845.1 - 0.0056 15.9 0.0 0.019 14.2 0.0 1.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GDP_Man_Dehyd PF16363.5 EPE26845.1 - 0.072 12.5 0.0 0.18 11.2 0.0 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glyco_tran_WecB PF03808.13 EPE26845.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family NST1 PF13945.6 EPE26846.1 - 1.4e-57 194.9 1.2 1.4e-57 194.9 1.2 4.4 2 2 2 4 4 4 1 Salt tolerance down-regulator Ras PF00071.22 EPE26847.1 - 1e-46 158.5 0.0 1.2e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE26847.1 - 7.5e-23 81.0 0.0 1.1e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE26847.1 - 1.8e-05 24.2 0.0 6.7e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EPE26847.1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EPE26847.1 - 0.064 13.0 0.0 3 7.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EPE26847.1 - 0.092 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EPE26847.1 - 0.2 11.8 0.0 0.34 11.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase MRP-L28 PF09812.9 EPE26848.1 - 7.4e-07 29.4 0.2 1.1e-06 28.9 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Inhibitor_Mig-6 PF11555.8 EPE26848.1 - 5.4 7.2 7.1 3.4 7.8 3.3 2.2 1 1 1 2 2 2 0 EGFR receptor inhibitor Mig-6 DUF1749 PF08538.10 EPE26849.1 - 2.6e-92 309.1 0.0 3.1e-92 308.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 EPE26849.1 - 0.0051 17.4 0.0 0.0086 16.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE26849.1 - 0.032 13.5 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EPE26849.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DEAD PF00270.29 EPE26851.1 - 9.5e-47 159.0 0.0 1.4e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE26851.1 - 1.6e-30 105.7 0.0 8.7e-30 103.3 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE26851.1 - 6.5e-05 23.0 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Brix PF04427.18 EPE26852.1 - 8e-50 169.6 0.0 1.1e-49 169.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain HD_4 PF13328.6 EPE26852.1 - 0.11 12.3 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 HD domain CoA_transf_3 PF02515.17 EPE26855.1 - 5.3e-124 414.1 0.0 6.1e-124 413.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III PHD PF00628.29 EPE26856.1 - 5.2e-10 39.1 7.0 8.2e-10 38.4 7.0 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EPE26856.1 - 0.00045 19.7 3.3 0.00045 19.7 3.3 2.3 2 1 0 2 2 2 1 PHD-finger C1_1 PF00130.22 EPE26856.1 - 0.0018 18.1 2.0 0.0018 18.1 2.0 2.1 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 EPE26856.1 - 0.0022 17.6 1.4 0.0022 17.6 1.4 1.6 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain zf-RRPl_C4 PF17026.5 EPE26856.1 - 0.13 12.4 0.2 0.23 11.6 0.2 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Prok-RING_1 PF14446.6 EPE26856.1 - 0.25 11.3 2.3 0.49 10.4 2.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DZR PF12773.7 EPE26856.1 - 5.6 7.1 7.2 33 4.6 7.2 2.1 1 1 0 1 1 1 0 Double zinc ribbon Peroxidase_2 PF01328.17 EPE26857.1 - 1.3e-46 159.5 0.0 2e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 GFA PF04828.14 EPE26858.1 - 3.5e-14 52.9 0.5 5.4e-14 52.3 0.5 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Lum_binding PF00677.17 EPE26860.1 - 1.5e-43 146.7 0.9 1.5e-21 76.1 0.2 2.1 2 0 0 2 2 2 2 Lumazine binding domain DUF411 PF04214.13 EPE26860.1 - 0.0029 17.5 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF YabP PF07873.11 EPE26860.1 - 0.013 15.3 0.0 5.4 6.9 0.0 3.4 3 1 0 3 3 3 0 YabP family AcetylCoA_hydro PF02550.15 EPE26860.1 - 0.073 13.0 0.2 0.24 11.3 0.2 1.8 1 1 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain Per1 PF04080.13 EPE26861.1 - 4.4e-104 347.8 11.7 6e-104 347.3 11.7 1.2 1 0 0 1 1 1 1 Per1-like family Cellulase PF00150.18 EPE26861.1 - 0.0013 18.3 0.0 0.0025 17.3 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) QueT PF06177.11 EPE26861.1 - 0.14 12.6 1.6 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 QueT transporter tRNA-synt_2b PF00587.25 EPE26862.1 - 1.4e-27 96.8 0.0 6.5e-26 91.4 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EPE26862.1 - 1.1e-10 41.4 0.0 2.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.17 EPE26863.1 - 4.2e-52 176.6 0.0 1.5e-51 174.8 0.0 2.1 1 0 0 1 1 1 1 CBF/Mak21 family Cnd1 PF12717.7 EPE26863.1 - 0.0017 18.4 0.6 0.0051 16.9 0.1 1.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 APS_kinase PF01583.20 EPE26865.1 - 4.2e-69 231.5 0.0 6.2e-69 230.9 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase 4HBT PF03061.22 EPE26865.1 - 1.1e-10 41.6 0.0 2.4e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily AAA_33 PF13671.6 EPE26865.1 - 0.0012 19.0 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EPE26865.1 - 0.076 13.6 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EPE26865.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain V-ATPase_C PF03223.15 EPE26866.1 - 1.1e-127 426.5 0.3 1.3e-127 426.3 0.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C mRNA_cap_C PF03919.15 EPE26866.1 - 0.12 13.0 0.3 0.42 11.3 0.0 1.9 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain IU_nuc_hydro PF01156.19 EPE26868.1 - 5.7e-42 144.3 0.1 7.1e-42 144.0 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF4951 PF16309.5 EPE26869.1 - 0.032 14.3 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) DUF726 PF05277.12 EPE26870.1 - 0.22 10.4 0.1 0.27 10.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) CobT PF06213.12 EPE26870.1 - 0.55 9.6 56.0 0.036 13.4 35.4 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 EPE26870.1 - 8.3 5.7 59.1 5.9 6.2 42.5 2.1 2 0 0 2 2 2 0 SDA1 GMC_oxred_N PF00732.19 EPE26872.1 - 2.2e-55 188.1 0.0 2.9e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE26872.1 - 2.9e-32 112.2 0.1 5.6e-32 111.2 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EPE26872.1 - 0.0009 19.4 0.1 0.0021 18.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPE26872.1 - 0.0022 17.1 0.0 0.0046 16.0 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EPE26872.1 - 0.017 14.4 0.0 0.81 8.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE26872.1 - 0.027 14.1 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE26872.1 - 0.033 13.4 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE26872.1 - 0.082 11.6 0.0 1.1 7.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 EPE26872.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 EPE26872.1 - 0.15 11.2 0.1 0.34 10.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 EPE26872.1 - 0.19 11.7 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding BAH PF01426.18 EPE26873.1 - 0.074 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 BAH domain Mod_r PF07200.13 EPE26874.1 - 8.2e-35 120.1 6.1 1.1e-34 119.6 6.1 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein APG6_N PF17675.1 EPE26874.1 - 0.013 16.0 2.2 0.03 14.8 2.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF641 PF04859.12 EPE26874.1 - 0.056 13.8 0.7 6.5 7.1 0.4 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Spc24 PF08286.11 EPE26874.1 - 0.14 12.4 0.5 0.27 11.5 0.5 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 AAA_32 PF13654.6 EPE26874.1 - 0.15 10.8 0.6 0.2 10.4 0.6 1.1 1 0 0 1 1 1 0 AAA domain F-box PF00646.33 EPE26876.1 - 0.0013 18.5 0.0 0.0034 17.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPE26876.1 - 0.012 15.5 2.0 0.013 15.4 0.1 2.1 2 0 0 2 2 2 0 F-box-like Nup84_Nup100 PF04121.13 EPE26878.1 - 1.1e-202 675.0 2.4 1.7e-202 674.4 2.4 1.3 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Rad60-SLD PF11976.8 EPE26879.1 - 2e-19 69.2 0.0 2.4e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EPE26879.1 - 8.5e-11 41.4 0.0 9.9e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Flavi_NS2B PF01002.19 EPE26880.1 - 1.9 8.4 4.0 0.32 10.8 0.4 1.5 2 0 0 2 2 2 0 Flavivirus non-structural protein NS2B Ligase_CoA PF00549.19 EPE26881.1 - 2.8e-34 118.2 2.9 1.3e-18 67.3 1.2 2.5 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 EPE26881.1 - 5e-17 62.4 1.0 1.5e-16 60.8 0.3 2.4 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 EPE26881.1 - 2.8e-08 33.6 0.1 0.00039 20.2 0.0 2.8 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.10 EPE26881.1 - 0.0013 18.3 0.0 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain BRCA-2_OB3 PF09104.10 EPE26881.1 - 0.076 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 CoA_binding_2 PF13380.6 EPE26881.1 - 0.13 12.7 0.0 0.42 11.1 0.0 1.9 1 0 0 1 1 1 0 CoA binding domain Aa_trans PF01490.18 EPE26882.1 - 1.5e-27 96.4 36.3 2.5e-27 95.7 36.3 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein OSTbeta PF15048.6 EPE26882.1 - 0.044 13.9 1.6 0.057 13.6 0.0 1.8 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein gpUL132 PF11359.8 EPE26882.1 - 0.15 11.6 0.1 0.43 10.1 0.1 1.8 1 0 0 1 1 1 0 Glycoprotein UL132 HD PF01966.22 EPE26884.1 - 4.7e-05 23.6 0.0 7.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 HD domain LIM PF00412.22 EPE26885.1 - 9.3e-24 83.4 32.6 1.6e-08 34.6 6.5 3.5 3 0 0 3 3 3 3 LIM domain DUF2321 PF10083.9 EPE26885.1 - 0.0012 18.5 0.9 0.0012 18.5 0.9 3.4 2 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2321) SMYLE_N PF18615.1 EPE26885.1 - 0.049 13.2 3.5 0.12 11.9 3.5 1.6 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain MFS_1 PF07690.16 EPE26886.1 - 1e-31 110.2 80.9 5e-25 88.2 52.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPE26886.1 - 1.4e-06 27.2 34.3 0.00036 19.2 13.8 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein TssN PF17555.2 EPE26886.1 - 1.3 8.3 10.0 0.12 11.8 2.6 2.3 2 0 0 2 2 2 0 Type VI secretion system, TssN FAD_binding_4 PF01565.23 EPE26887.1 - 1.6e-20 73.2 2.6 2.9e-20 72.4 2.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE26887.1 - 1.2e-08 34.9 0.3 3e-08 33.6 0.3 1.8 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.23 EPE26888.1 - 4e-21 75.2 2.1 9.1e-21 74.0 2.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE26888.1 - 1.1e-10 41.4 4.8 1.4e-10 41.1 0.8 2.8 3 0 0 3 3 3 1 Berberine and berberine like Cytokin-bind PF09265.10 EPE26888.1 - 0.068 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding EOS1 PF12326.8 EPE26889.1 - 0.13 12.2 0.0 0.13 12.2 0.0 2.6 3 1 0 3 3 3 0 N-glycosylation protein UbiA PF01040.18 EPE26890.1 - 5.1e-23 81.7 5.5 6.6e-23 81.3 5.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3981 PF13139.6 EPE26890.1 - 0.39 11.1 2.0 0.46 10.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3981) adh_short PF00106.25 EPE26891.1 - 8.3e-24 84.1 0.2 1.1e-23 83.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26891.1 - 2.8e-14 53.2 0.0 4.2e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE26891.1 - 2.8e-08 33.9 0.1 3.8e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE26891.1 - 0.00018 20.7 0.0 0.00022 20.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pyr_redox_2 PF07992.14 EPE26891.1 - 0.062 12.5 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EPE26891.1 - 0.16 12.4 0.0 0.5 10.8 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Transglut_core2 PF13369.6 EPE26891.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily GIDA PF01134.22 EPE26891.1 - 0.29 10.2 1.1 0.37 9.8 1.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A p450 PF00067.22 EPE26892.1 - 9e-37 126.9 0.0 1.2e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MA3 PF02847.17 EPE26893.1 - 5e-23 81.2 1.0 3.8e-22 78.4 0.2 2.5 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 EPE26893.1 - 9.9e-23 80.9 0.5 2.1e-22 79.8 0.1 1.8 2 0 0 2 2 2 1 MIF4G domain SRP14 PF02290.15 EPE26894.1 - 1.3e-26 92.7 0.0 2.3e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Rep_N PF08724.10 EPE26894.1 - 0.16 11.7 0.2 0.24 11.1 0.2 1.2 1 0 0 1 1 1 0 Rep protein catalytic domain like RRM_1 PF00076.22 EPE26896.1 - 2.5e-48 161.8 0.0 1e-17 63.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPE26896.1 - 0.00026 20.6 0.0 0.21 11.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.10 EPE26896.1 - 0.00032 20.3 0.0 0.014 15.0 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain RRM_3 PF08777.11 EPE26896.1 - 0.00032 20.7 0.0 0.62 10.1 0.0 3.3 3 0 0 3 3 3 1 RNA binding motif Limkain-b1 PF11608.8 EPE26896.1 - 0.0005 20.1 0.2 18 5.5 0.0 4.1 3 2 0 3 3 3 2 Limkain b1 PknH_C PF14032.6 EPE26896.1 - 0.11 12.4 0.0 45 3.8 0.0 3.2 3 0 0 3 3 3 0 PknH-like extracellular domain GRP PF07172.11 EPE26896.1 - 1 10.1 0.0 0.069 13.8 9.3 4.2 3 1 0 3 3 3 0 Glycine rich protein family THRAP3_BCLAF1 PF15440.6 EPE26896.1 - 5.3 5.9 20.6 7 5.5 20.6 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Got1 PF04178.12 EPE26897.1 - 1.6e-35 121.9 13.9 2.4e-35 121.3 13.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family La PF05383.17 EPE26898.1 - 1.8e-18 66.3 1.3 3e-18 65.6 1.3 1.3 1 0 0 1 1 1 1 La domain FtsJ PF01728.19 EPE26899.1 - 1e-15 58.3 0.0 1.6e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 EPE26899.1 - 0.041 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PAP_assoc PF03828.19 EPE26902.1 - 7.1e-19 67.8 0.4 1.9e-18 66.4 0.1 1.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EPE26902.1 - 4.6e-05 23.6 0.0 8.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EPE26902.1 - 0.0047 17.0 0.0 0.0094 16.0 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase MFS_1 PF07690.16 EPE26904.1 - 1.8e-25 89.6 12.5 1.8e-25 89.6 12.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily AhpC-TSA PF00578.21 EPE26905.1 - 1.2e-07 31.7 0.0 1.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family AhpC-TSA_2 PF13911.6 EPE26905.1 - 2.1e-06 27.8 0.0 3.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 EPE26905.1 - 9.7e-05 22.1 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin Darcynin PF17074.5 EPE26905.1 - 0.17 12.1 0.1 0.26 11.5 0.1 1.2 1 0 0 1 1 1 0 Darcynin, domain of unknown function MIP PF00230.20 EPE26906.1 - 2.6e-42 145.1 13.7 3.8e-42 144.5 13.7 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF4395 PF14340.6 EPE26906.1 - 5.2 7.4 12.4 6 7.2 1.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4395) ATPgrasp_ST PF14397.6 EPE26907.1 - 0.023 13.9 0.1 0.059 12.6 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GMC_oxred_N PF00732.19 EPE26908.1 - 1.9e-54 185.1 0.0 2.5e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE26908.1 - 2.7e-21 76.6 0.1 5.1e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EPE26908.1 - 0.061 12.4 0.9 9.4 5.2 0.6 2.2 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EPE26908.1 - 0.16 10.6 0.3 0.29 9.8 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein NUDIX PF00293.28 EPE26910.1 - 4.6e-07 29.9 0.5 1.2e-06 28.6 0.1 1.9 2 1 0 2 2 2 1 NUDIX domain NUDIX PF00293.28 EPE26911.1 - 1.2e-15 57.7 0.1 2e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain S1_2 PF13509.6 EPE26911.1 - 0.1 12.7 0.1 0.36 10.9 0.1 1.9 2 0 0 2 2 2 0 S1 domain PI3_PI4_kinase PF00454.27 EPE26913.1 - 1.4e-52 179.0 0.0 3.2e-52 177.8 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EPE26913.1 - 2.1e-43 148.9 9.4 3.6e-43 148.1 9.4 1.4 1 0 0 1 1 1 1 FAT domain UME PF08064.13 EPE26913.1 - 1.2e-34 118.3 1.8 3.8e-33 113.4 0.1 3.8 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 EPE26913.1 - 2.3e-12 46.5 0.1 6.1e-12 45.1 0.1 1.8 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.6 EPE26913.1 - 1.3 9.6 5.9 5.7 7.5 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat COX16 PF14138.6 EPE26914.1 - 4.1e-33 113.7 0.1 6e-33 113.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Dak1 PF02733.17 EPE26915.1 - 3.5e-104 348.0 0.0 6.5e-104 347.2 0.0 1.4 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 EPE26915.1 - 1.5e-39 135.7 1.3 2.3e-39 135.1 1.3 1.3 1 0 0 1 1 1 1 DAK2 domain F-box-like PF12937.7 EPE26916.1 - 0.0015 18.4 0.7 2.7 7.9 0.1 3.0 2 1 0 2 2 2 2 F-box-like C6_DPF PF10170.9 EPE26916.1 - 0.042 14.2 0.1 0.15 12.5 0.1 1.9 2 0 0 2 2 2 0 Cysteine-rich domain DUF5571 PF17732.1 EPE26916.1 - 0.22 10.9 0.4 0.34 10.3 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5571) zf-PARP PF00645.18 EPE26917.1 - 4.2e-17 62.8 0.2 3.3e-16 59.9 0.2 2.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Med17 PF10156.9 EPE26918.1 - 7.5e-114 381.0 0.1 1e-113 380.5 0.1 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Lipocalin_9 PF17186.4 EPE26918.1 - 0.037 14.3 0.4 0.51 10.6 0.0 2.5 2 0 0 2 2 2 0 Lipocalin-like domain SOAR PF16533.5 EPE26918.1 - 0.13 12.3 0.5 0.32 11.0 0.1 1.8 2 0 0 2 2 2 0 STIM1 Orai1-activating region PFK PF00365.20 EPE26919.1 - 1.6e-187 621.6 3.2 3.8e-105 351.3 0.6 2.2 2 0 0 2 2 2 2 Phosphofructokinase TgMIC1 PF11476.8 EPE26919.1 - 0.06 13.1 3.2 0.21 11.3 0.0 2.8 3 0 0 3 3 3 0 Toxoplasma gondii micronemal protein 1 TgMIC1 ISN1 PF06437.11 EPE26920.1 - 3.3e-201 668.5 0.0 3.7e-201 668.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase PG_binding_1 PF01471.18 EPE26920.1 - 0.12 12.6 0.1 23 5.3 0.0 2.5 2 0 0 2 2 2 0 Putative peptidoglycan binding domain DUF1691 PF07950.11 EPE26921.1 - 1.5e-36 125.3 10.3 6.6e-31 107.2 8.8 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Cytochrom_B559 PF00283.19 EPE26921.1 - 0.06 12.8 3.0 0.13 11.7 3.0 1.6 1 0 0 1 1 1 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Glyco_transf_15 PF01793.16 EPE26922.1 - 1.2e-132 442.2 6.2 1.4e-132 441.9 6.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase MFS_1 PF07690.16 EPE26923.1 - 2.9e-32 112.0 62.3 1.5e-31 109.6 44.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE26923.1 - 4e-09 35.8 40.5 2.6e-06 26.6 19.5 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Aldo_ket_red PF00248.21 EPE26924.1 - 1.3e-66 224.8 0.1 1.5e-66 224.6 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Spore_GerQ PF09671.10 EPE26924.1 - 0.095 12.7 0.0 0.51 10.4 0.0 2.3 2 1 1 3 3 3 0 Spore coat protein (Spore_GerQ) DUF4305 PF14146.6 EPE26925.1 - 0.17 12.1 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4305) Rieske PF00355.26 EPE26926.1 - 9.6e-12 44.7 0.0 1.6e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EPE26926.1 - 3.3e-10 40.3 0.3 3.3e-10 40.3 0.3 2.0 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Cpn60_TCP1 PF00118.24 EPE26927.1 - 1.2e-152 509.0 19.4 1.4e-152 508.8 19.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ProRS-C_1 PF09180.11 EPE26928.1 - 1.7e-22 79.4 0.9 3.7e-22 78.3 0.9 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 EPE26928.1 - 9.4e-20 70.6 0.0 2.1e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EPE26928.1 - 8.9e-18 64.9 0.0 1.5e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF3822 PF12864.7 EPE26928.1 - 0.16 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) MT0933_antitox PF14013.6 EPE26928.1 - 3.5 8.0 16.7 0.46 10.8 8.7 3.0 4 0 0 4 4 4 0 MT0933-like antitoxin protein DUF3950 PF13132.6 EPE26928.1 - 4.8 7.0 5.3 0.89 9.4 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3950) Pkinase PF00069.25 EPE26929.1 - 1.8e-61 207.8 0.2 8.3e-61 205.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE26929.1 - 1.2e-36 126.4 0.0 2.1e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 EPE26929.1 - 9.6e-25 86.5 34.4 2.8e-15 56.2 7.5 2.9 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.22 EPE26929.1 - 1.5e-20 72.8 33.2 2.3e-12 46.6 10.9 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EPE26929.1 - 5.2e-14 52.7 1.5 2e-13 50.8 1.5 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 EPE26929.1 - 9.3e-06 25.9 0.0 2.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EPE26929.1 - 0.025 13.9 0.0 0.062 12.6 0.0 1.6 2 0 0 2 2 2 0 Kinase-like DUF892 PF05974.12 EPE26929.1 - 2.6 8.1 9.8 0.13 12.3 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF892) DUF4449 PF14613.6 EPE26930.1 - 2.2e-05 24.6 0.1 2.2e-05 24.6 0.1 3.1 4 1 1 5 5 5 1 Protein of unknown function (DUF4449) DUF5365 PF17326.2 EPE26930.1 - 0.0045 17.4 0.3 5.7 7.4 0.1 3.0 2 0 0 2 2 2 2 Family of unknown function (DUF5365) Tricorn_C1 PF14684.6 EPE26930.1 - 0.011 15.8 0.2 0.082 13.0 0.1 2.6 1 1 1 2 2 2 0 Tricorn protease C1 domain DUF1828 PF08861.10 EPE26930.1 - 0.018 15.3 0.1 0.15 12.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF1828 LBP_BPI_CETP PF01273.25 EPE26930.1 - 0.022 14.3 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain DUF3053 PF11254.8 EPE26930.1 - 0.034 13.7 1.1 0.11 12.1 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) STI1 PF17830.1 EPE26930.1 - 0.043 13.8 0.9 0.2 11.6 0.3 2.2 2 0 0 2 2 2 0 STI1 domain D5_N PF08706.11 EPE26930.1 - 0.078 13.2 0.6 0.33 11.2 0.3 2.1 1 1 0 1 1 1 0 D5 N terminal like Pox_VLTF3 PF04947.14 EPE26930.1 - 0.1 12.3 4.1 0.11 12.3 0.2 2.7 3 0 0 3 3 3 0 Poxvirus Late Transcription Factor VLTF3 like ArAE_1_C PF11728.8 EPE26930.1 - 0.24 11.4 1.9 0.6 10.1 0.5 2.4 1 1 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain Sec34 PF04136.15 EPE26930.1 - 0.29 11.0 5.5 12 5.7 0.1 4.0 3 1 1 4 4 4 0 Sec34-like family AbiH PF14253.6 EPE26930.1 - 0.4 10.5 11.2 0.11 12.3 4.2 2.5 1 1 1 2 2 2 0 Bacteriophage abortive infection AbiH HEPN_Swt1 PF18731.1 EPE26930.1 - 0.46 10.8 4.0 8.7 6.7 0.1 3.8 4 0 0 4 4 4 0 Swt1-like HEPN DUF1574 PF07611.11 EPE26930.1 - 0.8 9.0 5.0 0.39 10.0 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1574) YkuI_C PF10388.9 EPE26930.1 - 1.5 8.6 5.8 2.6 7.8 0.2 3.3 3 1 1 4 4 4 0 EAL-domain associated signalling protein domain ABC_tran_CTD PF16326.5 EPE26930.1 - 2.1 8.7 4.4 2 8.7 0.5 3.1 3 1 1 4 4 4 0 ABC transporter C-terminal domain Zn_clus PF00172.18 EPE26931.1 - 0.075 13.2 7.8 0.13 12.4 7.8 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4718 PF15842.5 EPE26931.1 - 0.7 9.7 4.5 1.5 8.6 4.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) HypA PF01155.19 EPE26932.1 - 0.026 14.5 0.9 0.026 14.5 0.9 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2439 PF10382.9 EPE26933.1 - 4.7e-27 94.1 0.5 8.9e-27 93.2 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) SH3_1 PF00018.28 EPE26934.1 - 2.1e-14 52.9 0.1 3.6e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPE26934.1 - 5.4e-14 51.8 0.0 9.4e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 EPE26934.1 - 5.5e-13 49.1 0.2 7.4e-13 48.7 0.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.17 EPE26934.1 - 7.5e-11 41.6 0.0 1.4e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CALM_bind PF16025.5 EPE26935.1 - 0.042 14.3 2.4 0.15 12.6 2.4 2.0 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Rsa3 PF14615.6 EPE26936.1 - 2.6e-20 71.7 0.1 3.5e-20 71.3 0.1 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 NST1 PF13945.6 EPE26936.1 - 0.045 13.9 2.3 0.055 13.6 2.3 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Ribosomal_S10 PF00338.22 EPE26938.1 - 3.8e-28 97.6 0.3 4.5e-28 97.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.16 EPE26939.1 - 1.3e-09 37.6 0.1 2.3e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 CUE domain NOA36 PF06524.12 EPE26939.1 - 0.043 13.1 0.5 0.076 12.3 0.5 1.3 1 0 0 1 1 1 0 NOA36 protein Inp1 PF12634.7 EPE26940.1 - 2.9e-42 143.9 0.0 1.1e-41 142.0 0.0 2.1 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.11 EPE26941.1 - 1.4e-13 51.5 3.8 2.6e-10 40.8 3.8 2.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2890 PF11081.8 EPE26941.1 - 0.1 12.7 1.3 0.16 12.0 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SKG6 PF08693.10 EPE26941.1 - 0.85 9.1 7.9 39 3.8 7.9 2.8 1 1 0 1 1 1 0 Transmembrane alpha-helix domain FmdA_AmdA PF03069.15 EPE26942.1 - 7.1e-176 584.6 0.0 8.3e-176 584.3 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family PCI PF01399.27 EPE26943.1 - 4.6e-10 39.9 0.0 9.3e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 EPE26943.1 - 8.8e-06 25.2 0.4 1.7e-05 24.3 0.4 1.4 1 0 0 1 1 1 1 Rpn9 C-terminal helix NmrA PF05368.13 EPE26944.1 - 2.9e-15 56.5 0.0 4.1e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EPE26944.1 - 1.3e-13 51.0 0.0 2.3e-13 50.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPE26944.1 - 8.1e-11 42.1 0.0 1.2e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EPE26944.1 - 1.2e-08 34.3 0.0 2.3e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EPE26944.1 - 3.7e-07 29.9 0.1 1.5e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EPE26944.1 - 6.2e-07 28.8 0.0 2.2e-05 23.7 0.0 2.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EPE26944.1 - 4.5e-05 22.7 0.2 0.011 14.9 0.1 2.7 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.25 EPE26944.1 - 0.00058 19.4 0.0 0.00096 18.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE26944.1 - 0.036 14.0 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 KR domain RXLR PF16810.5 EPE26944.1 - 0.063 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity ApbA PF02558.16 EPE26944.1 - 0.13 11.9 0.0 0.64 9.7 0.0 2.2 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA N6-adenineMlase PF10237.9 EPE26945.1 - 5.8e-51 172.5 0.2 7.6e-51 172.1 0.2 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase GluRS_N PF18466.1 EPE26945.1 - 0.35 11.3 3.1 3.2 8.2 1.2 2.5 2 0 0 2 2 2 0 Glutamate--tRNA ligase N-terminal domain UCH PF00443.29 EPE26946.1 - 3.9e-51 174.0 6.6 4.8e-51 173.7 6.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPE26946.1 - 9.2e-33 114.2 10.3 1.5e-32 113.4 10.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EPE26946.1 - 0.00037 20.8 0.1 0.00037 20.8 0.1 2.5 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_C98 PF15499.6 EPE26946.1 - 2.1 7.8 9.4 3.8 6.9 1.0 3.4 2 1 1 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase TRAM_LAG1_CLN8 PF03798.16 EPE26947.1 - 1.8e-35 122.5 20.2 1.8e-35 122.5 20.2 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EPE26947.1 - 2.1e-25 88.1 1.3 1.5e-24 85.4 0.0 2.5 2 0 0 2 2 2 1 TRAM1-like protein PalH PF08733.10 EPE26948.1 - 1.8e-117 392.0 0.0 2.2e-117 391.8 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 SH3_1 PF00018.28 EPE26949.1 - 2.3e-05 23.9 0.0 7.2e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EPE26949.1 - 0.03 14.2 0.0 0.1 12.5 0.0 2.0 1 0 0 1 1 1 0 Variant SH3 domain Cdh1_DBD_1 PF18196.1 EPE26949.1 - 2.6 8.4 10.7 2.4 8.5 7.1 2.6 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 HAD_SAK_1 PF10307.9 EPE26950.1 - 9.5e-75 250.9 0.0 1.5e-74 250.3 0.0 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins HSF_DNA-bind PF00447.17 EPE26951.1 - 1e-31 109.4 1.5 1.8e-31 108.6 1.5 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 EPE26951.1 - 3.5e-20 72.2 0.0 1.3e-19 70.4 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain Ets PF00178.22 EPE26951.1 - 0.07 13.6 0.1 0.42 11.1 0.1 2.1 2 0 0 2 2 2 0 Ets-domain Mito_carr PF00153.27 EPE26952.1 - 5.1e-46 154.5 4.0 1e-16 60.6 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein SNF2_N PF00176.23 EPE26953.1 - 1.1e-57 195.4 0.0 2e-57 194.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EPE26953.1 - 4.3e-56 189.9 0.4 1.2e-55 188.4 0.4 1.8 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 EPE26953.1 - 1.9e-15 57.1 0.0 1e-14 54.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE26953.1 - 3.1e-08 33.8 0.0 5.8e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EPE26953.1 - 0.031 13.4 0.0 0.23 10.6 0.0 2.3 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Hydrophobin PF01185.18 EPE26954.1 - 0.00079 20.0 4.2 0.0022 18.6 4.2 1.8 1 1 0 1 1 1 1 Fungal hydrophobin DUF5473 PF17567.2 EPE26954.1 - 0.072 13.4 1.3 3.2 8.1 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5473) SURF6 PF04935.12 EPE26956.1 - 5.4e-51 173.2 36.7 5.4e-51 173.2 36.7 4.2 2 1 1 3 3 3 2 Surfeit locus protein 6 RRP14 PF15459.6 EPE26956.1 - 2.1e-18 66.7 2.3 2.1e-18 66.7 2.3 7.1 5 2 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 GPP34 PF05719.11 EPE26957.1 - 2.2e-70 236.9 0.2 2.7e-70 236.6 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PP-binding PF00550.25 EPE26958.1 - 3.1e-09 37.1 0.2 4e-09 36.7 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EPE26958.1 - 6.8e-07 29.4 0.2 9.1e-07 29.0 0.2 1.1 1 0 0 1 1 1 1 Acyl-carrier Fer4 PF00037.27 EPE26959.1 - 6.5e-14 51.1 15.4 6.2e-08 32.1 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EPE26959.1 - 5.6e-13 49.3 10.1 9.3e-13 48.6 10.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EPE26959.1 - 4.3e-10 40.4 7.4 7.4e-05 23.6 0.4 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EPE26959.1 - 7.1e-10 38.9 4.7 0.00012 22.1 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EPE26959.1 - 9.4e-09 35.3 20.9 1.7e-06 28.0 11.9 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EPE26959.1 - 2.8e-08 33.8 10.1 6.1e-08 32.7 10.1 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EPE26959.1 - 1.5e-06 28.0 17.1 0.0004 20.3 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 EPE26959.1 - 2.1e-06 28.1 9.6 0.00072 20.0 1.0 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EPE26959.1 - 4.2e-06 26.5 12.1 0.0099 15.9 1.7 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EPE26959.1 - 1e-05 25.6 11.7 0.00035 20.9 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EPE26959.1 - 0.0005 20.6 12.1 0.077 13.5 12.9 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EPE26959.1 - 0.033 14.4 5.8 0.68 10.2 0.2 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain ETF_QO PF05187.13 EPE26959.1 - 0.066 13.3 5.4 0.45 10.7 0.5 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_13 PF13370.6 EPE26959.1 - 0.077 13.5 15.2 0.75 10.4 4.3 2.6 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 EPE26959.1 - 0.085 13.1 9.1 1.3 9.2 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 EPE26959.1 - 0.22 12.5 15.5 0.43 11.6 3.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EPE26959.1 - 0.52 11.2 11.5 4.4 8.2 2.1 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain BTB PF00651.31 EPE26960.1 - 4.2e-10 39.8 0.0 6.8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain RPAP1_C PF08620.10 EPE26961.1 - 1.8e-25 88.8 0.0 4.1e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EPE26961.1 - 8.7e-19 67.0 6.3 8.7e-19 67.0 6.3 1.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal HEAT PF02985.22 EPE26961.1 - 0.15 12.4 0.1 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat HUN PF08729.10 EPE26962.1 - 7.3e-07 29.1 0.7 2.1e-06 27.6 0.2 2.0 2 0 0 2 2 2 1 HPC2 and ubinuclein domain Mito_carr PF00153.27 EPE26963.1 - 2.5e-51 171.6 2.7 1.3e-20 73.0 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Complex1_LYR PF05347.15 EPE26964.1 - 0.069 13.2 0.1 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 Complex 1 protein (LYR family) DUF2370 PF10176.9 EPE26965.1 - 6.5e-93 310.5 0.0 1.6e-92 309.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) DUF2561 PF10812.8 EPE26965.1 - 0.024 14.7 0.8 0.045 13.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) PCMT PF01135.19 EPE26966.1 - 5.5e-58 196.2 0.0 6.9e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EPE26966.1 - 0.00043 20.1 0.1 0.00075 19.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE26966.1 - 0.0016 19.1 0.1 0.0027 18.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE26966.1 - 0.0028 17.5 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EPE26966.1 - 0.0029 17.6 0.0 0.0045 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EPE26966.1 - 0.012 16.6 0.1 0.029 15.4 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EPE26966.1 - 0.075 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.12 EPE26966.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 EPE26966.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 EPE26966.1 - 0.16 12.7 0.1 0.3 11.8 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EPE26966.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain UCH PF00443.29 EPE26968.1 - 1.5e-39 136.1 0.0 4.3e-39 134.6 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 EPE26968.1 - 3.1e-39 132.7 4.4 1e-12 47.8 0.1 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.6 EPE26968.1 - 3.1e-09 36.9 0.0 1.5e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF4241 PF14025.6 EPE26968.1 - 0.023 15.0 0.2 0.063 13.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) FliD_C PF07195.12 EPE26968.1 - 0.045 13.2 0.6 0.091 12.2 0.6 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Pox_A_type_inc PF04508.12 EPE26968.1 - 0.17 11.8 4.4 0.19 11.7 2.3 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF1640 PF07798.11 EPE26968.1 - 0.52 10.3 3.7 1.1 9.3 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) HalX PF08663.10 EPE26968.1 - 1.2 9.5 4.8 4 7.8 4.8 1.9 1 0 0 1 1 1 0 HalX domain Tim17 PF02466.19 EPE26969.1 - 4.8e-06 26.9 8.2 2.2e-05 24.8 7.3 2.2 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Phage_holin_3_3 PF16083.5 EPE26969.1 - 0.013 15.6 0.3 0.029 14.5 0.3 1.7 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III TBCC PF07986.12 EPE26970.1 - 1.9e-28 98.6 0.5 3.1e-28 97.9 0.5 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EPE26970.1 - 3.4e-10 40.4 0.0 6.1e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Med9 PF07544.13 EPE26971.1 - 2.6e-15 56.3 1.6 3.8e-15 55.7 1.6 1.4 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Phage_GP20 PF06810.11 EPE26971.1 - 0.0025 17.6 0.4 0.0032 17.3 0.4 1.1 1 0 0 1 1 1 1 Phage minor structural protein GP20 Spc29 PF17082.5 EPE26971.1 - 0.0053 16.6 0.1 0.0066 16.3 0.1 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 UPF0242 PF06785.11 EPE26971.1 - 0.0067 16.5 0.8 0.0091 16.1 0.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Formin_GBD_N PF18382.1 EPE26971.1 - 0.0082 16.6 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 Formin N-terminal GTPase-binding domain Fib_alpha PF08702.10 EPE26971.1 - 0.024 14.8 0.1 0.03 14.5 0.1 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Med21 PF11221.8 EPE26971.1 - 0.047 13.9 3.2 0.055 13.7 3.0 1.3 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF16 PF01519.16 EPE26971.1 - 0.06 13.8 1.3 0.084 13.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 SlyX PF04102.12 EPE26971.1 - 0.11 13.1 1.6 0.14 12.8 0.7 1.6 2 0 0 2 2 2 0 SlyX DUF5082 PF16888.5 EPE26971.1 - 0.17 12.2 2.8 0.18 12.1 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) iPGM_N PF06415.13 EPE26972.1 - 1e-78 263.7 0.0 1.4e-78 263.3 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EPE26972.1 - 9.1e-68 228.3 0.0 1e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EPE26972.1 - 5.4e-06 26.0 0.0 1.1e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EPE26972.1 - 0.00051 19.7 0.0 0.0012 18.5 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase ketoacyl-synt PF00109.26 EPE26975.1 - 5.5e-71 239.1 0.0 1.1e-70 238.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EPE26975.1 - 7e-60 202.0 0.0 1.9e-59 200.6 0.0 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EPE26975.1 - 5.3e-50 170.7 3.4 1.8e-49 169.0 0.0 2.7 3 0 0 3 3 3 1 Acyl transferase domain PS-DH PF14765.6 EPE26975.1 - 3.9e-45 154.4 0.1 6.1e-45 153.7 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EPE26975.1 - 5.2e-39 132.9 0.0 1.2e-38 131.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EPE26975.1 - 3.5e-17 63.0 0.0 9.8e-17 61.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EPE26975.1 - 6.4e-16 58.4 0.7 3.2e-12 46.3 0.0 4.7 4 1 1 5 5 5 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 EPE26975.1 - 3.1e-15 57.4 0.0 2.3e-14 54.6 0.0 2.6 3 0 0 3 3 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPE26975.1 - 1.7e-13 50.7 0.0 6.8e-13 48.7 0.0 2.1 2 0 0 2 2 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EPE26975.1 - 6.6e-13 49.1 0.1 6.4e-10 39.5 0.0 2.9 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 EPE26975.1 - 3.5e-09 37.3 0.0 7.4e-08 33.0 0.0 3.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE26975.1 - 4.6e-09 36.3 0.0 1.4e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EPE26975.1 - 9.3e-09 35.2 2.4 2.3e-06 27.4 0.0 4.5 6 0 0 6 6 5 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.6 EPE26975.1 - 1.6e-07 31.3 0.0 4.8e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 EPE26975.1 - 2.5e-07 30.6 0.3 7.1e-07 29.1 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 EPE26975.1 - 4.1e-07 30.6 0.0 1.7e-06 28.6 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 EPE26975.1 - 3e-06 27.5 0.1 2.5e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.9 EPE26975.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 EPE26975.1 - 0.016 14.6 0.0 0.053 12.8 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 EPE26975.1 - 0.023 13.8 0.0 0.15 11.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.6 EPE26975.1 - 0.036 15.1 0.0 0.11 13.5 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.15 EPE26975.1 - 0.049 12.8 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.13 EPE26975.1 - 0.076 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Thiolase_N PF00108.23 EPE26975.1 - 0.077 12.3 0.1 0.28 10.5 0.1 1.9 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_28 PF02636.17 EPE26975.1 - 0.098 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RAB3GAP2_C PF14656.6 EPE26975.1 - 0.13 10.5 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus MFS_1 PF07690.16 EPE26976.1 - 9.2e-42 143.2 41.4 3e-41 141.5 41.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE26976.1 - 1.4e-14 53.5 18.4 1.8e-14 53.1 18.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPE26976.1 - 4e-10 39.1 6.9 4e-10 39.1 6.9 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 EPE26976.1 - 0.00055 18.5 4.5 0.00055 18.5 4.5 1.9 3 0 0 3 3 3 1 Transmembrane secretion effector 7TMR-DISM_7TM PF07695.11 EPE26976.1 - 6.3 6.6 36.4 0.88 9.4 7.9 2.6 2 1 0 2 2 2 0 7TM diverse intracellular signalling Abhydrolase_3 PF07859.13 EPE26978.1 - 2.4e-27 96.2 0.0 2.5e-26 92.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.22 EPE26979.1 - 8e-62 209.5 0.0 1e-61 209.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2953 PF11167.8 EPE26979.1 - 0.06 13.4 0.1 6.4 6.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) HAP1_N PF04849.13 EPE26979.1 - 0.098 11.8 0.7 0.49 9.6 1.1 1.8 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Pyr_redox_3 PF13738.6 EPE26980.1 - 2.1e-14 53.5 0.8 1.9e-08 34.0 0.6 3.6 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EPE26980.1 - 2.6e-14 52.5 0.2 6.2e-14 51.3 0.2 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EPE26980.1 - 1.4e-13 50.7 0.5 1.3e-11 44.2 0.1 3.3 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EPE26980.1 - 1.9e-11 44.0 0.0 6.3e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE26980.1 - 5.7e-06 25.8 0.0 0.00055 19.3 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE26980.1 - 0.0001 22.0 0.4 0.033 13.8 0.1 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EPE26980.1 - 0.00028 20.9 0.0 0.098 12.6 0.0 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EPE26980.1 - 0.012 16.2 0.0 2 9.0 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE26980.1 - 0.16 11.2 1.2 0.7 9.1 0.1 2.3 3 0 0 3 3 3 0 Thi4 family p450 PF00067.22 EPE26982.1 - 1.4e-34 119.6 0.0 2.1e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 GFO_IDH_MocA PF01408.22 EPE26982.1 - 8.1e-06 26.7 0.1 3e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Adenine_glyco PF03352.13 EPE26982.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyladenine glycosylase GhoS PF11080.8 EPE26982.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease GhoS DAGAT PF03982.13 EPE26982.1 - 0.14 11.0 0.3 0.91 8.4 0.0 2.2 3 0 0 3 3 3 0 Diacylglycerol acyltransferase ATPgrasp_N PF18130.1 EPE26983.1 - 3.5e-16 59.5 0.0 1e-15 58.0 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 EPE26983.1 - 3.9e-08 33.0 0.0 3.1e-07 30.1 0.0 2.5 2 1 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EPE26983.1 - 1.8e-06 27.6 0.0 1.7e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EPE26983.1 - 0.00016 21.7 0.0 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain TTL PF03133.15 EPE26983.1 - 0.0078 15.4 0.0 0.46 9.6 0.0 2.2 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 EPE26983.1 - 0.049 12.9 0.0 0.19 11.0 0.0 1.9 3 0 0 3 3 3 0 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 EPE26983.1 - 0.067 12.4 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 YheC/D like ATP-grasp CPSase_L_D2 PF02786.17 EPE26983.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ABC_membrane PF00664.23 EPE26984.1 - 1e-95 320.5 36.1 1.1e-48 166.3 16.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EPE26984.1 - 6.1e-71 237.3 0.0 3.7e-35 121.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EPE26984.1 - 6.6e-14 51.9 5.9 0.00018 21.0 1.4 4.6 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EPE26984.1 - 2.8e-09 37.6 4.5 0.0011 19.3 0.1 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 EPE26984.1 - 3.7e-09 36.8 0.1 0.0018 18.0 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EPE26984.1 - 2.2e-08 33.7 1.1 0.0072 16.0 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EPE26984.1 - 1.2e-07 30.9 0.5 0.0091 14.8 0.1 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EPE26984.1 - 3.8e-07 30.1 0.0 0.015 15.2 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 EPE26984.1 - 4e-07 29.5 0.0 0.0094 15.3 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 EPE26984.1 - 4.9e-07 30.1 0.2 0.083 13.2 0.0 3.9 3 2 0 3 3 2 2 AAA domain AAA_23 PF13476.6 EPE26984.1 - 4.3e-05 24.1 0.0 0.19 12.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF87 PF01935.17 EPE26984.1 - 4.6e-05 23.6 0.2 0.035 14.2 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_21 PF13304.6 EPE26984.1 - 6.4e-05 22.9 1.8 0.46 10.2 0.1 3.4 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EPE26984.1 - 9.3e-05 22.2 0.0 1.5 8.5 0.0 3.6 4 0 0 4 4 4 2 AAA domain G-alpha PF00503.20 EPE26984.1 - 0.00013 21.2 0.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_24 PF13479.6 EPE26984.1 - 0.00053 19.8 0.0 0.41 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EPE26984.1 - 0.0015 19.0 0.1 2.3 8.8 0.0 3.3 2 1 1 3 3 3 1 AAA domain DUF815 PF05673.13 EPE26984.1 - 0.0017 17.6 0.0 0.58 9.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EPE26984.1 - 0.0019 18.2 0.0 2.3 8.2 0.0 3.5 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EPE26984.1 - 0.0035 17.4 0.0 3.4 7.8 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 EPE26984.1 - 0.007 16.6 4.2 3.8 7.8 0.3 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 EPE26984.1 - 0.016 15.1 0.0 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_7 PF12775.7 EPE26984.1 - 0.035 13.6 0.0 9.5 5.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 EPE26984.1 - 0.046 13.1 0.0 27 4.1 0.0 3.7 4 0 0 4 4 4 0 Bacterial TniB protein PRK PF00485.18 EPE26984.1 - 0.05 13.3 0.0 5.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Dynamin_N PF00350.23 EPE26984.1 - 0.08 13.0 0.2 28 4.7 0.0 3.5 3 0 0 3 3 3 0 Dynamin family Roc PF08477.13 EPE26984.1 - 0.083 13.1 0.0 17 5.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EPE26984.1 - 0.085 13.0 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 EPE26984.1 - 0.1 12.5 0.0 3 7.7 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Aminotran_3 PF00202.21 EPE26985.1 - 3.8e-85 286.0 0.1 4.7e-85 285.7 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III adh_short PF00106.25 EPE26986.1 - 4.9e-18 65.3 0.0 6.1e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE26986.1 - 1.1e-13 51.3 0.0 1.3e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EPE26986.1 - 0.0024 17.8 0.0 0.092 12.6 0.0 2.4 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EPE26986.1 - 0.039 13.9 0.1 0.073 13.0 0.1 1.6 1 1 0 1 1 1 0 KR domain p450 PF00067.22 EPE26987.1 - 1.9e-63 214.9 0.0 2.2e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C14 PF00656.22 EPE26988.1 - 4.7e-62 210.2 0.1 5.8e-62 209.9 0.1 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EPE26988.1 - 0.18 11.8 0.6 0.57 10.1 0.0 2.1 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Cnn_1N PF07989.11 EPE26989.1 - 2.2e-24 85.4 3.9 2.2e-24 85.4 3.9 19.2 12 5 6 19 19 19 2 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 EPE26989.1 - 1.9e-14 54.0 0.1 1.9e-14 54.0 0.1 6.3 6 1 0 6 6 6 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.9 EPE26989.1 - 0.00031 20.8 14.2 0.00031 20.8 14.2 15.7 3 2 9 12 12 12 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 She9_MDM33 PF05546.11 EPE26989.1 - 0.0066 16.3 3.1 0.0066 16.3 3.1 13.6 3 3 11 16 16 16 1 She9 / Mdm33 family Strep_SA_rep PF06696.11 EPE26989.1 - 0.035 14.1 3.1 22 5.2 0.1 4.4 3 0 0 3 3 3 0 Streptococcal surface antigen repeat SGT1 PF07093.11 EPE26990.1 - 4.8e-94 315.9 16.0 3.1e-84 283.5 0.0 2.0 1 1 1 2 2 2 2 SGT1 protein THUMP PF02926.17 EPE26992.1 - 6.2e-06 26.4 0.1 2.1e-05 24.7 0.1 1.9 1 1 0 1 1 1 1 THUMP domain NmrA PF05368.13 EPE26993.1 - 2.4e-09 37.1 0.0 1.5e-06 27.9 0.0 2.8 2 1 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 EPE26993.1 - 3.3e-07 30.4 0.0 7.6e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE26993.1 - 0.00034 20.1 0.0 0.027 13.9 0.0 3.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family Peripla_BP_6 PF13458.6 EPE26993.1 - 0.0025 17.5 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Tmp39 PF10271.9 EPE26993.1 - 0.074 12.0 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein PIF1 PF05970.14 EPE26994.1 - 7.9e-43 147.0 0.1 2.8e-29 102.4 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EPE26994.1 - 6.7e-21 74.9 0.0 2.1e-20 73.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain Cauli_VI PF01693.16 EPE26994.1 - 5.1e-15 55.5 0.5 1.2e-14 54.3 0.5 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin AAA_19 PF13245.6 EPE26994.1 - 3.2e-13 50.3 0.0 7.5e-13 49.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 EPE26994.1 - 6.8e-09 36.1 0.0 1.9e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EPE26994.1 - 5.8e-07 29.6 0.5 0.0012 18.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EPE26994.1 - 9.4e-06 26.1 0.0 2.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DEAD PF00270.29 EPE26994.1 - 1.8e-05 24.6 0.2 0.018 14.8 0.1 2.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase AAA_5 PF07728.14 EPE26994.1 - 0.00037 20.5 2.5 0.0049 16.9 0.6 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EPE26994.1 - 0.001 18.2 0.0 0.013 14.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 EPE26994.1 - 0.0019 17.2 0.0 0.0043 16.0 0.0 1.5 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Microtub_bd PF16796.5 EPE26994.1 - 0.0026 17.7 0.0 0.0067 16.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding FtsK_SpoIIIE PF01580.18 EPE26994.1 - 0.0039 16.6 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family NACHT PF05729.12 EPE26994.1 - 0.0059 16.5 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain UvrD-helicase PF00580.21 EPE26994.1 - 0.01 15.4 1.0 0.022 14.3 1.0 1.8 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 EPE26994.1 - 0.016 14.5 0.0 0.049 12.9 0.0 1.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EPE26994.1 - 0.017 15.1 0.1 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_7 PF12775.7 EPE26994.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_32 PF13654.6 EPE26994.1 - 0.026 13.3 0.0 0.089 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EPE26994.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Herpes_Helicase PF02689.14 EPE26994.1 - 0.11 10.5 0.0 0.65 7.8 0.0 1.9 2 0 0 2 2 2 0 Helicase TsaE PF02367.17 EPE26994.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE UvrD_C_2 PF13538.6 EPE26994.1 - 0.12 12.2 0.3 0.85 9.5 0.1 2.6 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain RNA_helicase PF00910.22 EPE26994.1 - 0.14 12.6 0.0 0.4 11.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 EPE26994.1 - 0.16 11.7 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EPE26994.1 - 0.17 11.2 0.0 0.44 9.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EPE26994.1 - 0.17 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pox_A32 PF04665.12 EPE26994.1 - 0.18 11.2 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Fungal_trans PF04082.18 EPE26995.1 - 3.2e-15 55.9 0.7 4.7e-15 55.3 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE26995.1 - 1.1e-06 28.7 10.1 2.3e-06 27.6 10.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAF_flag10 PF01973.18 EPE26996.1 - 0.0067 16.1 0.0 0.0087 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF115 Nrap_D4 PF17405.2 EPE26997.1 - 5.7e-63 212.1 0.0 1.2e-62 211.0 0.0 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 EPE26997.1 - 2.7e-54 183.3 0.1 1.2e-53 181.1 0.1 2.0 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 EPE26997.1 - 6.5e-48 162.6 0.2 1.3e-47 161.7 0.2 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 EPE26997.1 - 2.7e-47 160.4 0.0 5.8e-46 156.0 0.0 2.7 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 EPE26997.1 - 2.9e-42 144.5 0.1 6.2e-42 143.4 0.0 1.6 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D6 PF17407.2 EPE26997.1 - 1.4e-32 112.8 0.0 4.2e-32 111.2 0.0 1.9 1 0 0 1 1 1 1 Nrap protein domain 6 Cys_Met_Meta_PP PF01053.20 EPE26998.1 - 2.2e-32 112.1 0.0 3.1e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EPE26998.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II CSN8_PSD8_EIF3K PF10075.9 EPE26999.1 - 1.8e-44 151.2 0.0 2.5e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PDCD2_C PF04194.13 EPE27000.1 - 3.8e-48 163.9 0.0 2.5e-45 154.7 0.0 2.4 2 1 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain Pkinase PF00069.25 EPE27001.1 - 1.3e-62 211.6 0.0 1.8e-62 211.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE27001.1 - 4.8e-47 160.4 0.0 7.5e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE27001.1 - 4.3e-09 36.1 0.0 1.2e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EPE27001.1 - 0.0055 15.5 0.0 0.014 14.2 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EPE27001.1 - 0.0068 16.4 0.3 0.07 13.0 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EPE27001.1 - 0.013 14.9 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_23 PF13476.6 EPE27002.1 - 4.6e-19 69.7 3.1 4.6e-19 69.7 3.1 5.1 2 2 1 4 4 4 1 AAA domain SMC_N PF02463.19 EPE27002.1 - 3.2e-18 66.0 26.8 1.7e-17 63.6 26.9 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EPE27002.1 - 6e-07 29.5 8.8 6e-07 29.5 8.8 2.7 2 0 0 2 2 2 1 AAA ATPase domain KxDL PF10241.9 EPE27002.1 - 0.00015 22.0 3.8 0.00015 22.0 3.8 5.3 5 1 2 7 7 7 1 Uncharacterized conserved protein AAA_29 PF13555.6 EPE27002.1 - 0.0049 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EPE27002.1 - 0.0057 16.5 1.1 0.15 11.8 0.1 2.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EPE27002.1 - 0.0097 16.1 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit COQ9 PF08511.11 EPE27003.1 - 7.9e-28 96.0 0.2 1.3e-27 95.4 0.2 1.3 1 0 0 1 1 1 1 COQ9 DHFR_2 PF06442.11 EPE27004.1 - 0.064 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 R67 dihydrofolate reductase Esterase_phd PF10503.9 EPE27005.1 - 1.2e-20 73.9 2.1 1.7e-20 73.4 2.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EPE27005.1 - 2.2e-09 37.1 0.3 3.2e-09 36.6 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EPE27005.1 - 0.0073 15.6 0.4 0.25 10.6 0.3 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EPE27005.1 - 0.013 15.4 0.1 0.02 14.7 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 EPE27005.1 - 0.027 13.4 1.0 0.034 13.0 0.4 1.4 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_2 PF02230.16 EPE27005.1 - 0.055 13.3 0.3 0.65 9.8 0.3 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase HET PF06985.11 EPE27006.1 - 6.4e-31 107.7 0.1 1.3e-30 106.7 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2199 PF09965.9 EPE27006.1 - 0.057 13.5 0.3 12 5.9 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2199) Adenyl_transf PF04439.12 EPE27006.1 - 0.096 11.8 0.5 0.15 11.1 0.5 1.2 1 0 0 1 1 1 0 Streptomycin adenylyltransferase Y2_Tnp PF04986.13 EPE27006.1 - 0.12 12.4 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Putative transposase Dehydratase_hem PF13816.6 EPE27008.1 - 2.6e-89 299.7 0.0 2.9e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase Zn_clus PF00172.18 EPE27009.1 - 2.6e-07 30.6 15.0 2.9e-07 30.5 13.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE27009.1 - 6.9e-07 28.6 0.8 1.5e-06 27.5 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CagZ PF09053.10 EPE27009.1 - 0.11 12.1 0.4 0.27 10.8 0.4 1.6 1 0 0 1 1 1 0 CagZ CN_hydrolase PF00795.22 EPE27010.1 - 2.1e-42 145.3 0.0 2.7e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Git3 PF11710.8 EPE27011.1 - 1.2e-25 90.5 12.0 4.4e-25 88.6 12.0 1.9 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EPE27011.1 - 4.6e-12 45.8 0.3 4.6e-12 45.8 0.3 3.0 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 EPE27011.1 - 0.001 18.3 10.6 0.002 17.3 10.6 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Oxidored_q3 PF00499.20 EPE27011.1 - 0.81 9.4 10.9 0.011 15.4 2.7 2.2 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 MFS_1 PF07690.16 EPE27012.1 - 2e-33 115.8 26.5 2e-33 115.8 26.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE27012.1 - 3.8e-09 35.9 6.9 3.8e-09 35.9 6.9 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter CTV_P6 PF06706.11 EPE27012.1 - 1.6 8.5 6.1 18 5.1 0.1 3.3 3 0 0 3 3 3 0 Citrus tristeza virus 6-kDa protein AMP-binding PF00501.28 EPE27013.1 - 1.1e-65 221.9 0.0 1.5e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AnmK PF03702.14 EPE27013.1 - 7.7e-53 179.9 0.0 1.1e-52 179.3 0.0 1.2 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase AMP-binding_C PF13193.6 EPE27013.1 - 1.4e-07 32.3 0.0 3.2e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PIG-S PF10510.9 EPE27014.1 - 1.4e-156 522.3 0.0 1.8e-156 522.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Diphthamide_syn PF01866.17 EPE27015.1 - 5.3e-82 275.7 0.0 6.7e-82 275.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein PHtD_u1 PF16645.5 EPE27015.1 - 6 7.4 10.0 16 6.0 10.0 1.8 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein MARVEL PF01284.23 EPE27017.1 - 0.0049 16.9 16.8 0.0067 16.5 16.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4293 PF14126.6 EPE27017.1 - 3.8 7.7 7.7 2.4 8.4 4.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) HET PF06985.11 EPE27018.1 - 2.5e-10 40.9 5.9 4.1e-08 33.7 0.7 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF3425 PF11905.8 EPE27019.1 - 3.5e-12 46.4 0.0 5.8e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Abhydrolase_6 PF12697.7 EPE27020.1 - 2.5e-15 57.7 1.0 2.9e-15 57.5 1.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 EPE27020.1 - 0.14 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 EPE27020.1 - 0.22 11.1 0.3 0.75 9.3 0.3 1.8 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Methyltransf_25 PF13649.6 EPE27021.1 - 1.2e-12 48.4 0.0 2.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE27021.1 - 1.5e-11 44.8 0.0 2.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE27021.1 - 3.4e-06 26.9 0.0 4.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE27021.1 - 1.2e-05 25.9 0.0 1.9e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE27021.1 - 0.00059 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EPE27021.1 - 0.00078 19.3 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPE27021.1 - 0.0033 17.0 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PLA2_B PF01735.18 EPE27025.1 - 4e-193 642.3 8.9 4.8e-193 642.1 8.9 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Prenyltrans PF00432.21 EPE27026.1 - 7.2e-38 128.0 18.4 4.4e-10 39.1 0.3 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat NTP_transferase PF00483.23 EPE27027.1 - 2.9e-52 177.7 0.0 5.4e-52 176.8 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 EPE27027.1 - 5.8e-18 63.9 19.0 1.4e-10 40.5 1.8 3.7 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EPE27027.1 - 3.1e-10 40.6 0.0 4.2e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EPE27027.1 - 2.2e-06 27.3 10.2 2.3e-06 27.2 0.5 3.3 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EPE27027.1 - 0.0002 19.7 0.1 0.00029 19.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Velvet PF11754.8 EPE27029.1 - 5.9e-40 137.8 2.5 1e-29 104.2 0.3 4.4 2 2 1 3 3 3 2 Velvet factor MWFE PF15879.5 EPE27030.1 - 0.026 14.7 3.4 0.043 14.0 3.4 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit MOZ_SAS PF01853.18 EPE27031.1 - 2.1e-74 249.1 0.0 3.2e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EPE27031.1 - 1e-20 73.1 5.5 1.1e-20 73.0 2.9 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain PHD_4 PF16866.5 EPE27031.1 - 4e-11 42.8 6.7 4e-11 42.8 6.7 1.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EPE27031.1 - 0.00017 21.4 7.4 0.00017 21.4 7.4 2.1 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 EPE27031.1 - 0.018 14.9 0.3 0.042 13.7 0.3 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Acetyltransf_7 PF13508.7 EPE27031.1 - 0.026 14.9 0.0 0.11 13.0 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Abi_C PF14355.6 EPE27031.1 - 0.044 13.9 0.2 0.14 12.3 0.1 1.8 2 0 0 2 2 2 0 Abortive infection C-terminus zf-Sec23_Sec24 PF04810.15 EPE27031.1 - 0.85 9.7 2.7 42 4.3 0.0 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger PHD_2 PF13831.6 EPE27031.1 - 1.4 8.6 3.8 0.88 9.2 1.3 2.0 2 0 0 2 2 2 0 PHD-finger Egh16-like PF11327.8 EPE27032.1 - 7.7e-50 169.9 12.3 7.7e-50 169.9 12.3 2.7 2 1 0 2 2 2 1 Egh16-like virulence factor AA_permease_2 PF13520.6 EPE27033.1 - 0.11 11.3 2.6 0.14 11.0 2.6 1.1 1 0 0 1 1 1 0 Amino acid permease MotB_plug PF13677.6 EPE27033.1 - 0.12 12.0 0.3 0.2 11.3 0.3 1.4 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB DUF4131 PF13567.6 EPE27033.1 - 0.12 12.0 0.9 0.24 11.1 0.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Wzy_C PF04932.15 EPE27033.1 - 0.2 11.2 0.8 0.45 10.1 0.9 1.6 1 1 0 1 1 1 0 O-Antigen ligase MENTAL PF10457.9 EPE27034.1 - 0.13 12.1 1.0 0.17 11.6 1.0 1.2 1 0 0 1 1 1 0 Cholesterol-capturing domain Tannase PF07519.11 EPE27035.1 - 2.7e-111 372.8 1.8 3.4e-111 372.5 1.8 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EPE27035.1 - 0.047 13.2 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Mannosyl_trans2 PF04188.13 EPE27038.1 - 7.4e-49 167.3 16.9 1.6e-48 166.1 16.9 1.5 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) BLM10_mid PF16507.5 EPE27040.1 - 2.2e-202 673.4 0.0 3.9e-202 672.6 0.0 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EPE27040.1 - 1.1e-30 105.4 0.0 5.2e-30 103.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 EPE27040.1 - 2.3e-19 69.4 0.7 1.1e-18 67.2 0.2 2.6 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal IFRD PF05004.13 EPE27040.1 - 0.0017 17.5 0.0 1.2 8.2 0.0 2.9 2 1 0 2 2 2 2 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 EPE27040.1 - 0.21 11.9 2.7 45 4.7 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat HET PF06985.11 EPE27041.1 - 4.3e-34 118.0 0.0 6.4e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tat PF00539.18 EPE27042.1 - 0.00047 20.3 2.0 0.00078 19.6 2.0 1.3 1 0 0 1 1 1 1 Transactivating regulatory protein (Tat) Herpes_UL95 PF03038.14 EPE27042.1 - 0.4 9.8 0.6 0.48 9.5 0.6 1.1 1 0 0 1 1 1 0 UL95 family IBR PF01485.21 EPE27043.1 - 3e-09 37.0 26.1 4.6e-06 26.8 4.8 4.5 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain DUF982 PF06169.12 EPE27043.1 - 0.0017 18.3 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF982) P-mevalo_kinase PF04275.14 EPE27044.1 - 1.6e-21 76.4 0.0 3e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Phosphomevalonate kinase Pribosyltran PF00156.27 EPE27044.1 - 7.6e-20 71.0 0.0 1.3e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_4 PF01565.23 EPE27044.1 - 1.4e-13 50.8 3.9 3.2e-13 49.6 3.9 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE27044.1 - 0.00019 21.5 0.0 0.00061 19.8 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like UPRTase PF14681.6 EPE27044.1 - 0.0012 18.3 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Methyltransf_23 PF13489.6 EPE27044.1 - 0.0035 17.2 0.0 0.13 12.1 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain TPR_10 PF13374.6 EPE27045.1 - 3.4e-18 64.9 16.5 1.3e-08 34.4 0.2 6.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 EPE27045.1 - 2.9e-17 62.7 21.1 6.3e-07 29.6 0.2 6.6 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EPE27045.1 - 8.4e-05 22.4 6.5 0.077 13.2 0.3 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EPE27045.1 - 0.00029 20.5 2.7 0.52 10.2 0.5 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 EPE27045.1 - 0.0046 17.4 9.2 1.4 9.8 0.6 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat NB-ARC PF00931.22 EPE27045.1 - 0.0099 15.1 0.0 3.1 6.9 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain ATPase_2 PF01637.18 EPE27045.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_8 PF13181.6 EPE27045.1 - 0.032 14.4 4.6 2.1 8.8 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_16 PF13191.6 EPE27045.1 - 0.037 14.4 0.1 0.27 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain TPR_9 PF13371.6 EPE27045.1 - 0.05 13.7 0.1 9.8 6.4 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.22 EPE27046.1 - 1.4e-31 109.8 0.0 1.6e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Na_Ca_ex PF01699.24 EPE27047.1 - 1.3e-44 151.8 40.7 3.2e-24 85.6 17.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Stn1 PF10451.9 EPE27048.1 - 2.3e-16 59.5 0.4 1.4e-07 30.7 0.5 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 EPE27048.1 - 0.0013 18.6 0.2 0.11 12.5 0.2 2.5 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 EPE27048.1 - 0.0039 17.0 0.8 0.16 11.8 0.6 2.4 1 1 1 2 2 2 1 RecQ-mediated genome instability protein 2 DnaJ PF00226.31 EPE27049.1 - 4.3e-21 74.8 6.1 5.6e-21 74.4 4.4 2.2 2 0 0 2 2 2 1 DnaJ domain WYL_3 PF18488.1 EPE27049.1 - 0.0031 17.8 0.7 0.006 16.9 0.7 1.4 1 0 0 1 1 1 1 WYL domain Porphobil_deam PF01379.20 EPE27050.1 - 1.3e-77 259.9 0.0 1.9e-77 259.4 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EPE27050.1 - 6.3e-18 64.9 0.1 1.5e-17 63.7 0.1 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain GCV_H PF01597.19 EPE27051.1 - 1.8e-33 115.0 1.0 2.3e-33 114.7 1.0 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Ras PF00071.22 EPE27052.1 - 4.2e-31 107.7 0.1 5.7e-31 107.3 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE27052.1 - 1.3e-23 83.5 0.1 2.1e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE27052.1 - 1.3e-06 28.0 0.1 1.8e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EPE27052.1 - 9.4e-05 21.9 0.2 0.00013 21.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EPE27052.1 - 0.00043 19.3 0.5 0.22 10.3 0.0 2.3 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) DUF1590 PF07629.11 EPE27052.1 - 0.25 11.2 6.4 0.53 10.1 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) G-alpha PF00503.20 EPE27052.1 - 0.86 8.7 5.1 0.47 9.5 0.1 2.4 2 1 1 3 3 3 0 G-protein alpha subunit PLAC8 PF04749.17 EPE27053.1 - 2.7e-16 60.4 4.1 8.3e-16 58.8 4.1 1.9 1 0 0 1 1 1 1 PLAC8 family CLN3 PF02487.17 EPE27054.1 - 0.036 13.1 0.5 0.061 12.4 0.5 1.3 1 0 0 1 1 1 0 CLN3 protein Connexin PF00029.19 EPE27054.1 - 0.086 12.6 11.3 0.26 11.0 11.4 2.0 1 1 0 1 1 1 0 Connexin AIMP2_LysRS_bd PF16780.5 EPE27054.1 - 0.12 12.2 0.2 0.44 10.3 0.0 2.1 2 1 1 3 3 3 0 AIMP2 lysyl-tRNA synthetase binding domain SRP-alpha_N PF04086.13 EPE27054.1 - 8.7 6.2 28.1 15 5.4 28.1 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TIP120 PF08623.10 EPE27055.1 - 1.5e-68 229.9 4.4 8.8e-68 227.3 0.1 3.9 5 0 0 5 5 5 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 EPE27055.1 - 1.2e-15 57.7 16.6 0.014 15.8 0.4 8.5 8 1 1 9 9 9 5 HEAT repeats HEAT PF02985.22 EPE27055.1 - 4.5e-14 51.3 9.7 0.14 12.5 0.0 11.0 12 0 0 12 12 12 4 HEAT repeat RTP1_C1 PF10363.9 EPE27055.1 - 1.9e-10 40.9 6.1 0.0008 19.6 0.0 6.8 6 1 0 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 EPE27055.1 - 2.1e-07 31.1 11.9 0.069 13.2 0.0 6.0 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EPE27055.1 - 0.00027 21.5 0.0 46 4.7 0.0 7.2 6 3 2 8 8 8 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EPE27055.1 - 0.00029 20.5 2.2 0.21 11.1 0.1 4.4 4 1 1 5 5 5 1 CLASP N terminal DUF3361 PF11841.8 EPE27055.1 - 0.0061 16.5 0.9 6.9 6.6 0.0 5.1 5 1 1 7 7 7 1 Domain of unknown function (DUF3361) Proteasom_PSMB PF10508.9 EPE27055.1 - 0.013 14.1 2.7 0.036 12.6 0.2 2.9 4 0 0 4 4 4 0 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 EPE27055.1 - 0.016 15.7 18.5 8.6 7.0 0.1 10.1 12 2 3 15 15 14 0 HEAT-like repeat Cnd3 PF12719.7 EPE27055.1 - 0.018 14.3 0.6 19 4.3 0.0 4.4 5 0 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain GFA PF04828.14 EPE27056.1 - 4.9e-07 30.0 0.0 0.0001 22.6 0.0 2.3 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 EPE27056.1 - 0.72 9.8 5.3 1 9.3 0.1 2.8 3 0 0 3 3 3 0 Nudix N-terminal Peptidase_M28 PF04389.17 EPE27057.1 - 2e-42 145.2 0.0 2.6e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EPE27057.1 - 2e-11 43.8 0.5 4.3e-11 42.7 0.5 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EPE27057.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 SesA PF17107.5 EPE27058.1 - 0.0041 17.3 0.0 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases GMC_oxred_N PF00732.19 EPE27059.1 - 5.1e-78 262.5 0.0 7.1e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE27059.1 - 4.8e-34 117.9 0.0 1.1e-33 116.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EPE27059.1 - 0.00013 21.2 0.1 0.12 11.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EPE27059.1 - 0.00025 20.2 0.1 0.00038 19.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EPE27059.1 - 0.015 14.9 0.8 0.063 12.9 0.8 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE27059.1 - 0.017 14.4 0.0 0.04 13.2 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE27059.1 - 0.053 12.7 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Dynamin_N PF00350.23 EPE27060.1 - 2.6e-17 63.4 0.4 5.9e-17 62.2 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EPE27060.1 - 8.6e-10 38.7 0.0 4.8e-09 36.3 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EPE27060.1 - 6.4e-07 29.1 0.2 1.5e-05 24.6 0.3 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF2205 PF10224.9 EPE27060.1 - 0.00064 19.7 2.6 0.00071 19.5 0.1 2.3 2 0 0 2 2 2 1 Short coiled-coil protein IIGP PF05049.13 EPE27060.1 - 0.037 13.1 0.0 0.084 11.9 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PMEI PF04043.15 EPE27060.1 - 0.048 14.0 1.1 0.11 12.8 1.1 1.6 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor cobW PF02492.19 EPE27060.1 - 0.062 12.9 0.1 1.9 8.0 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 EPE27060.1 - 0.062 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EPE27060.1 - 0.13 12.8 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EPE27060.1 - 0.13 12.4 0.1 2.2 8.5 0.0 2.6 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Snf7 PF03357.21 EPE27061.1 - 2.2e-37 128.3 17.3 2.9e-37 127.9 17.3 1.1 1 0 0 1 1 1 1 Snf7 YlqD PF11068.8 EPE27061.1 - 0.008 16.5 15.8 0.23 11.9 2.5 2.2 1 1 1 2 2 2 2 YlqD protein Ist1 PF03398.14 EPE27061.1 - 0.078 12.9 5.4 0.15 12.0 5.4 1.5 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Exonuc_VII_L PF02601.15 EPE27061.1 - 0.16 11.5 4.2 0.22 11.0 4.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 EPE27061.1 - 0.54 9.6 5.2 0.76 9.1 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3958 PF13125.6 EPE27061.1 - 3.4 7.9 13.4 0.28 11.4 6.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3958) PP2C PF00481.21 EPE27062.1 - 5.6e-63 213.0 0.9 2e-51 175.1 0.5 3.2 1 1 0 2 2 2 2 Protein phosphatase 2C Glyco_hydro81C PF17652.1 EPE27063.1 - 8.2e-158 525.2 0.6 1e-157 524.8 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EPE27063.1 - 4.4e-116 387.6 0.1 6e-116 387.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Utp14 PF04615.13 EPE27064.1 - 2.9e-212 707.3 66.6 2.9e-212 707.3 66.6 2.1 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.9 EPE27065.1 - 2.6e-18 65.9 0.5 3.2e-18 65.6 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Peptidase_M54 PF07998.11 EPE27066.1 - 8.2e-07 29.2 0.1 3.7e-06 27.0 0.1 2.0 2 0 0 2 2 2 1 Peptidase family M54 Metallopep PF12044.8 EPE27066.1 - 0.14 10.7 0.2 0.26 9.9 0.2 1.3 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_4 PF13583.6 EPE27066.1 - 0.22 11.1 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Ribonuclease_T2 PF00445.18 EPE27067.1 - 2.1e-43 148.7 0.6 2.1e-43 148.7 0.6 1.5 2 0 0 2 2 2 1 Ribonuclease T2 family GT-D PF08759.11 EPE27067.1 - 0.0017 18.1 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase GT-D fold Aldolase_II PF00596.21 EPE27068.1 - 1.4e-29 103.3 0.5 1.8e-29 103.0 0.5 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain PUMA PF15826.5 EPE27069.1 - 0.85 9.8 10.5 0.13 12.5 4.7 2.0 1 1 0 2 2 2 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Abhydrolase_3 PF07859.13 EPE27070.1 - 1.8e-33 116.2 0.0 2.8e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EPE27070.1 - 0.0013 18.6 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 EPE27070.1 - 0.0015 18.1 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family COesterase PF00135.28 EPE27070.1 - 0.0066 15.4 0.0 0.018 13.9 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 EPE27070.1 - 0.007 17.0 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 EPE27070.1 - 0.015 14.2 0.0 0.065 12.1 0.0 1.7 1 1 1 2 2 2 0 Steryl acetyl hydrolase BAAT_C PF08840.11 EPE27070.1 - 0.021 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 EPE27070.1 - 0.023 13.4 0.0 0.036 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Fungal_trans PF04082.18 EPE27071.1 - 2.5e-18 66.1 0.1 1.6e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE27071.1 - 1.1e-08 35.0 8.0 1.9e-08 34.2 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-amylase PF00128.24 EPE27072.1 - 4.2e-25 89.0 2.5 1.6e-24 87.1 2.5 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 EPE27072.1 - 0.00044 18.6 1.7 1.5 6.9 0.1 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 EPE27072.1 - 0.008 16.3 0.1 0.019 15.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) HRXXH PF13933.6 EPE27074.1 - 1.7e-10 40.9 2.4 1.5e-09 37.8 2.4 2.0 1 1 0 1 1 1 1 Putative peptidase family Fungal_trans_2 PF11951.8 EPE27075.1 - 7.6e-10 38.2 4.0 1.2e-09 37.5 4.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE27075.1 - 9e-09 35.3 8.7 2.3e-08 34.0 8.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.22 EPE27076.1 - 1.8e-67 227.9 4.6 2.1e-67 227.7 4.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Cation_ATPase_C PF00689.21 EPE27076.1 - 0.031 14.0 6.4 0.98 9.1 0.1 2.5 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus MDM10 PF12519.8 EPE27077.1 - 3.6e-154 514.1 2.3 3.9e-133 444.7 0.4 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 EPE27077.1 - 1.3e-06 28.1 0.1 0.067 12.7 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic porin RL10P_insert PF17777.1 EPE27078.1 - 2.9e-25 88.0 0.1 7.6e-25 86.7 0.0 1.8 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EPE27078.1 - 2e-20 72.8 0.0 3.1e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.8 EPE27079.1 - 1.3e-26 93.0 4.5 1.3e-26 93.0 4.5 1.9 3 0 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EPE27079.1 - 6.2e-17 61.2 0.2 2.4e-16 59.3 0.2 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPE27079.1 - 3.7e-05 23.8 0.0 5.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif DUF3752 PF12572.8 EPE27079.1 - 0.028 15.0 1.6 0.065 13.8 1.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3752) L51_S25_CI-B8 PF05047.16 EPE27080.1 - 5.5e-12 45.4 0.0 8.3e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Phage_holin_2_4 PF16082.5 EPE27081.1 - 0.18 11.5 1.4 0.28 10.9 1.4 1.4 1 1 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF456 PF04306.13 EPE27082.1 - 0.015 15.6 0.1 0.018 15.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_YMGG PF13441.6 EPE27082.1 - 0.029 14.1 1.1 0.045 13.5 1.1 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 EPE27082.1 - 0.14 12.1 3.1 0.24 11.3 3.1 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EPE27082.1 - 0.45 10.5 3.8 0.71 9.9 3.8 1.3 1 0 0 1 1 1 0 Glycine zipper PsaA_PsaB PF00223.19 EPE27083.1 - 0.056 11.6 0.0 0.056 11.6 0.0 1.0 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein NTase_sub_bind PF08780.11 EPE27083.1 - 0.097 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like DivIC PF04977.15 EPE27083.1 - 0.11 12.3 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator Innexin PF00876.18 EPE27084.1 - 0.0013 18.1 0.1 0.0016 17.8 0.1 1.1 1 0 0 1 1 1 1 Innexin FAM209 PF15206.6 EPE27084.1 - 0.014 15.2 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 FAM209 family DUF2207 PF09972.9 EPE27085.1 - 0.083 11.6 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1295 PF06966.12 EPE27086.1 - 1.8e-43 148.8 0.1 1.2e-41 142.7 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EPE27086.1 - 0.0025 18.2 0.3 0.055 13.9 0.0 2.7 3 1 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 EPE27086.1 - 0.0063 16.5 0.0 0.5 10.3 0.0 2.3 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EPE27086.1 - 0.01 16.2 0.6 0.18 12.2 0.0 2.8 2 1 1 3 3 3 0 Phospholipid methyltransferase Inv-AAD PF18785.1 EPE27087.1 - 1.7e-61 205.8 0.3 2e-61 205.5 0.3 1.1 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EPE27087.1 - 1.6e-13 50.4 0.0 2.3e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EPE27087.1 - 0.0019 17.9 0.0 0.0058 16.4 0.0 1.7 1 1 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 EPE27087.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain WD40 PF00400.32 EPE27088.1 - 1.5e-27 95.2 4.6 3.2e-06 27.8 0.0 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE27088.1 - 2.9e-05 24.3 0.0 0.54 10.6 0.0 3.4 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nudix_N_2 PF14803.6 EPE27088.1 - 0.0028 17.5 2.6 0.008 16.1 2.6 1.8 1 0 0 1 1 1 1 Nudix N-terminal TF_Zn_Ribbon PF08271.12 EPE27088.1 - 0.09 12.3 0.5 0.26 10.8 0.5 1.9 1 1 0 1 1 1 0 TFIIB zinc-binding Ge1_WD40 PF16529.5 EPE27088.1 - 0.19 10.7 0.2 0.92 8.4 0.2 2.1 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF382 PF04037.13 EPE27089.1 - 2e-59 199.3 0.6 2e-59 199.3 0.6 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 EPE27089.1 - 4.2e-20 71.4 4.1 8.9e-20 70.3 4.1 1.6 1 0 0 1 1 1 1 PSP DUF2749 PF10907.8 EPE27089.1 - 0.13 12.5 0.1 0.4 10.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) HOOK PF05622.12 EPE27090.1 - 0.032 12.4 4.2 0.043 12.0 4.2 1.1 1 0 0 1 1 1 0 HOOK protein DUF1907 PF08925.11 EPE27090.1 - 0.086 12.3 0.2 0.21 11.0 0.0 1.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1907) WASH-7_C PF14746.6 EPE27090.1 - 0.15 11.8 3.5 0.22 11.2 3.5 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal DivIC PF04977.15 EPE27090.1 - 4.5 7.1 9.6 9.3 6.1 9.6 1.5 1 0 0 1 1 1 0 Septum formation initiator RVT_1 PF00078.27 EPE27091.1 - 0.0019 17.7 0.3 0.25 10.9 0.0 2.9 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHH PF10283.9 EPE27091.1 - 5 7.2 10.1 33 4.6 1.1 3.4 3 0 0 3 3 3 0 PBZ domain Chromo PF00385.24 EPE27092.1 - 1.6e-08 34.3 0.2 3.2e-08 33.3 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf_CCCH_4 PF18345.1 EPE27092.1 - 0.00064 19.7 35.6 0.0019 18.2 1.6 4.9 4 1 0 4 4 4 3 Zinc finger domain zf-CCCH PF00642.24 EPE27092.1 - 0.0087 16.0 0.6 0.0087 16.0 0.6 4.4 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EPE27092.1 - 0.32 11.7 15.4 5.3 7.8 0.1 4.6 3 1 1 4 4 4 0 Torus domain zf-CCCH_4 PF18044.1 EPE27092.1 - 0.51 10.2 36.2 0.21 11.4 2.0 4.9 5 1 0 5 5 5 0 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EPE27092.1 - 0.85 9.9 14.1 0.67 10.2 2.9 3.7 4 0 0 4 4 4 0 Zinc-finger containing family Ras PF00071.22 EPE27093.1 - 1.9e-63 212.9 0.2 2.2e-63 212.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE27093.1 - 2.1e-35 121.5 0.2 3e-35 121.0 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE27093.1 - 3e-13 49.6 0.1 3.9e-13 49.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPE27093.1 - 8.5e-08 32.3 0.1 1.3e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPE27093.1 - 9.7e-05 22.3 0.1 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EPE27093.1 - 0.00028 20.5 0.1 0.0011 18.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EPE27093.1 - 0.00038 19.9 0.1 0.0006 19.2 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EPE27093.1 - 0.0028 17.9 0.0 0.018 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 EPE27093.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EPE27093.1 - 0.013 15.5 0.1 0.038 14.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EPE27093.1 - 0.022 15.2 0.1 0.034 14.5 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EPE27093.1 - 0.027 15.0 0.1 0.043 14.3 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EPE27093.1 - 0.027 14.2 0.1 0.061 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EPE27093.1 - 0.039 13.4 0.0 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein SpoIIID PF12116.8 EPE27093.1 - 0.091 12.9 0.1 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D FeoB_N PF02421.18 EPE27093.1 - 0.1 12.1 0.1 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.6 EPE27093.1 - 0.12 12.2 0.6 0.16 11.7 0.5 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EPE27093.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Brix PF04427.18 EPE27095.1 - 1.8e-39 135.9 0.0 2.2e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain ATP-synt_ab PF00006.25 EPE27096.1 - 5.1e-72 242.0 0.0 7.3e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EPE27096.1 - 1.8e-47 160.8 0.1 3e-47 160.1 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EPE27096.1 - 4.3e-15 56.0 3.0 1.1e-14 54.7 3.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RbcS PF12338.8 EPE27096.1 - 0.051 13.8 0.4 0.84 9.9 0.4 2.6 2 0 0 2 2 2 0 Ribulose-1,5-bisphosphate carboxylase small subunit Arb2 PF09757.9 EPE27097.1 - 6e-93 310.7 0.0 9e-93 310.1 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 EPE27097.1 - 7.1e-84 281.9 0.0 9.9e-84 281.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Gp_dh_C PF02800.20 EPE27098.1 - 1.4e-71 239.2 0.1 2.2e-71 238.6 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EPE27098.1 - 4.6e-38 129.6 0.0 1.1e-37 128.3 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EPE27098.1 - 0.015 15.5 0.1 0.045 13.9 0.1 2.0 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus APH PF01636.23 EPE27100.1 - 7.5e-09 35.9 0.0 1.8e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE27100.1 - 8.1e-05 22.3 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EPE27100.1 - 0.11 11.8 0.0 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase COX4 PF02936.14 EPE27101.1 - 8.6e-47 158.6 0.1 1e-46 158.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 EPE27101.1 - 0.012 16.1 2.1 0.024 15.1 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) DUF1104 PF06518.11 EPE27101.1 - 0.16 12.3 0.1 0.52 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) AAA_2 PF07724.14 EPE27102.1 - 2.7e-37 128.5 0.0 5.7e-37 127.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EPE27102.1 - 1.4e-14 54.6 0.1 3.8e-14 53.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EPE27102.1 - 2.9e-07 30.6 0.0 6e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPE27102.1 - 8.8e-06 26.0 0.0 3.1e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain MCM PF00493.23 EPE27102.1 - 1.1e-05 24.7 0.0 2.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain ClpB_D2-small PF10431.9 EPE27102.1 - 1.5e-05 25.0 0.0 0.054 13.6 0.0 2.5 2 0 0 2 2 2 2 C-terminal, D2-small domain, of ClpB protein AAA_7 PF12775.7 EPE27102.1 - 0.00027 20.5 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 EPE27102.1 - 0.00059 20.3 0.5 0.0023 18.3 0.1 2.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 EPE27102.1 - 0.00073 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EPE27102.1 - 0.0031 17.2 0.0 0.016 14.9 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.6 EPE27102.1 - 0.0033 17.2 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EPE27102.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EPE27102.1 - 0.041 13.3 0.4 0.35 10.2 0.0 2.3 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EPE27102.1 - 0.044 14.3 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 EPE27102.1 - 0.094 12.5 0.1 0.38 10.5 0.0 2.0 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EPE27102.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 EPE27102.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EPE27102.1 - 0.13 12.5 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EPE27102.1 - 0.13 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 EPE27102.1 - 0.17 11.7 1.1 0.46 10.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Alpha-amylase_C PF02806.18 EPE27103.1 - 1.7e-26 92.5 0.0 7.8e-26 90.4 0.0 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EPE27103.1 - 1.7e-18 66.8 0.0 4.3e-18 65.4 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EPE27103.1 - 3.1e-15 56.6 0.4 9.3e-11 41.9 0.1 2.5 2 1 1 3 3 3 2 Alpha amylase, catalytic domain ATP-synt_ab PF00006.25 EPE27104.1 - 1.1e-61 208.2 0.0 1.7e-61 207.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EPE27104.1 - 2.8e-22 79.0 1.3 6.6e-22 77.8 0.5 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 EPE27104.1 - 0.012 16.1 0.1 0.79 10.1 0.0 3.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EPE27104.1 - 0.014 15.4 0.4 0.029 14.3 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 EPE27104.1 - 0.014 14.6 0.5 0.081 12.1 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EPE27104.1 - 0.015 15.2 0.0 0.046 13.6 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EPE27104.1 - 0.016 15.5 1.3 0.47 10.8 0.2 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EPE27104.1 - 0.029 13.7 0.3 0.061 12.7 0.2 1.6 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 EPE27104.1 - 0.051 13.5 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 EPE27104.1 - 0.075 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EPE27104.1 - 0.13 12.6 0.1 0.47 10.8 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF4618 PF15397.6 EPE27104.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) T3SS_ATPase_C PF18269.1 EPE27104.1 - 0.21 11.5 0.7 0.85 9.5 0.7 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain GAF_2 PF13185.6 EPE27106.1 - 2.4e-05 24.6 0.0 0.00011 22.5 0.0 2.1 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 EPE27106.1 - 0.0081 16.8 0.0 0.028 15.1 0.0 1.9 1 0 0 1 1 1 1 GAF domain Glyco_transf_17 PF04724.13 EPE27107.1 - 2.7e-50 171.4 0.6 1.6e-49 168.9 0.6 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 17 DUF4131 PF13567.6 EPE27107.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SpoIIE PF07228.12 EPE27108.1 - 2.4e-10 40.7 0.0 1.2e-09 38.3 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EPE27108.1 - 4.7e-08 33.0 0.0 0.00021 21.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EPE27108.1 - 1.7e-06 27.8 0.1 3.4e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C HSCB_C PF07743.13 EPE27109.1 - 3e-17 62.9 9.0 8.8e-17 61.4 8.4 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EPE27109.1 - 1.3e-06 28.4 0.1 3e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DUF2508 PF10704.9 EPE27109.1 - 0.28 11.4 3.3 0.69 10.1 3.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) adh_short_C2 PF13561.6 EPE27110.1 - 2.1e-31 109.3 0.0 1.2e-30 106.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE27110.1 - 6.8e-25 87.7 0.0 1e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE27110.1 - 2.3e-05 24.4 0.0 0.00016 21.6 0.0 2.0 2 0 0 2 2 2 1 KR domain dCMP_cyt_deam_1 PF00383.23 EPE27111.1 - 6e-14 51.8 0.1 7.6e-14 51.4 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EPE27111.1 - 9.5e-09 35.6 2.6 1.1e-07 32.1 0.2 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EPE27111.1 - 0.011 15.4 0.7 0.95 9.0 0.0 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases RRM_1 PF00076.22 EPE27112.1 - 7.5e-08 32.1 0.0 2.1e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sigma70_r1_1 PF03979.14 EPE27112.1 - 0.042 13.9 1.9 0.084 12.9 1.9 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 HET PF06985.11 EPE27113.1 - 1.9e-27 96.4 0.4 3.6e-27 95.5 0.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Hce2 PF14856.6 EPE27113.1 - 0.1 12.9 0.1 0.36 11.1 0.1 1.9 2 0 0 2 2 2 0 Pathogen effector; putative necrosis-inducing factor Amidoligase_2 PF12224.8 EPE27114.1 - 2.6e-15 56.8 0.0 4.2e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Putative amidoligase enzyme SH3BGR PF04908.15 EPE27115.1 - 8.9e-05 22.6 0.0 0.00028 21.0 0.0 1.9 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein TPP_enzyme_N PF02776.18 EPE27116.1 - 1.8e-42 144.9 0.1 3.8e-42 143.8 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EPE27116.1 - 7.2e-33 113.2 0.1 1.8e-32 111.9 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EPE27116.1 - 2.1e-21 76.3 0.0 2.4e-20 72.9 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 EPE27116.1 - 6.6e-05 22.8 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit B12-binding PF02310.19 EPE27116.1 - 0.0046 17.0 2.4 0.0071 16.4 0.3 2.4 3 0 0 3 3 3 1 B12 binding domain SDA1 PF05285.12 EPE27119.1 - 0.024 14.1 40.7 0.0085 15.6 31.4 2.1 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 EPE27119.1 - 0.73 8.0 37.7 0.042 12.1 29.5 2.0 2 0 0 2 2 2 0 Nop14-like family AAA_15 PF13175.6 EPE27119.1 - 3 7.5 14.9 0.27 10.9 9.6 1.8 2 0 0 2 2 2 0 AAA ATPase domain CDC27 PF09507.10 EPE27119.1 - 7.6 5.8 37.0 5.4 6.3 0.7 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 SHS2_Rpb7-N PF03876.17 EPE27120.1 - 6.1e-16 58.5 0.0 1e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EPE27120.1 - 3.5e-12 46.5 0.0 6.3e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.11 EPE27121.1 - 1.4e-25 89.2 1.1 2.1e-25 88.6 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) zf-CHY PF05495.12 EPE27122.1 - 0.93 10.0 5.5 9.7 6.8 1.9 2.4 2 0 0 2 2 2 0 CHY zinc finger DUF1770 PF08589.10 EPE27124.1 - 0.12 13.3 5.4 6.3 7.8 0.0 3.4 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1770) FAD_binding_4 PF01565.23 EPE27125.1 - 5.8e-19 68.2 1.2 1.3e-18 67.1 1.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE27125.1 - 0.037 14.1 0.1 0.083 13.0 0.1 1.6 1 0 0 1 1 1 0 Berberine and berberine like Peptidase_S28 PF05577.12 EPE27126.1 - 1.7e-52 178.7 0.0 3.6e-52 177.6 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 ORC5_C PF14630.6 EPE27128.1 - 4.2e-77 259.5 0.0 6.2e-77 258.9 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EPE27128.1 - 7.5e-12 46.0 0.1 1.9e-11 44.7 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EPE27128.1 - 0.049 14.1 0.0 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EPE27128.1 - 0.075 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Fungal_trans_2 PF11951.8 EPE27129.1 - 2.6e-09 36.4 0.2 3.8e-09 35.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE27129.1 - 3e-07 30.5 9.3 4.9e-07 29.8 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.11 EPE27130.1 - 0.11 13.0 9.0 0.027 14.9 5.2 1.9 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Stevor PF17410.2 EPE27130.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Sporozoite_P67 PF05642.11 EPE27130.1 - 0.37 8.8 7.5 0.69 7.9 7.5 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4512 PF14975.6 EPE27130.1 - 0.79 10.5 3.3 44 4.9 2.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) VTC PF09359.10 EPE27131.1 - 5.2e-90 301.6 0.8 5.2e-90 301.6 0.8 1.8 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 EPE27131.1 - 7.6e-14 51.9 0.8 7.6e-14 51.9 0.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 EPE27131.1 - 6.4e-06 26.3 21.3 0.0011 19.0 1.4 4.0 3 1 1 4 4 4 2 SPX domain SLBP_RNA_bind PF15247.6 EPE27131.1 - 0.023 14.8 0.1 0.065 13.4 0.1 1.7 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain Arm PF00514.23 EPE27132.1 - 2.3e-07 30.6 19.8 0.00099 19.1 0.0 7.7 9 0 0 9 9 9 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EPE27132.1 - 0.00012 22.0 8.3 2.7 8.5 0.1 6.7 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 EPE27132.1 - 0.00086 19.8 0.1 0.00086 19.8 0.1 6.8 10 0 0 10 10 10 1 HEAT-like repeat Cyclin PF08613.11 EPE27133.1 - 8.1e-33 114.1 0.0 1.9e-32 112.9 0.0 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EPE27133.1 - 0.00033 20.4 0.0 0.00059 19.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain MIB_HERC2 PF06701.13 EPE27133.1 - 0.17 12.1 0.3 0.35 11.1 0.3 1.4 1 0 0 1 1 1 0 Mib_herc2 Use1 PF09753.9 EPE27136.1 - 0.00046 20.0 0.0 0.00046 20.0 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Apc15p PF05841.11 EPE27137.1 - 8.9e-17 62.0 8.2 3e-15 57.1 8.2 2.4 1 1 0 1 1 1 1 Apc15p protein Spidroin_MaSp PF11260.8 EPE27137.1 - 0.042 14.1 0.8 0.08 13.2 0.8 1.3 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 GATase_2 PF00310.21 EPE27138.1 - 2.1e-182 606.5 0.0 3.1e-182 606.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EPE27138.1 - 2e-117 392.5 0.1 5e-84 282.5 0.0 2.3 1 1 1 2 2 2 2 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EPE27138.1 - 4.6e-109 364.2 0.0 1.3e-108 362.8 0.0 1.7 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EPE27138.1 - 2.6e-86 288.1 2.5 4.3e-86 287.4 2.5 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EPE27138.1 - 2.2e-23 82.9 0.2 9.5e-23 80.8 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EPE27138.1 - 1.4e-21 76.4 0.1 2.9e-21 75.3 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 EPE27138.1 - 4.4e-09 36.5 0.1 1.7e-08 34.6 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EPE27138.1 - 1.2e-08 35.4 0.0 3.8e-05 24.2 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE27138.1 - 3.7e-07 30.1 0.6 0.0014 18.3 0.2 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPE27138.1 - 6.3e-06 25.7 0.2 0.013 14.8 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EPE27138.1 - 1.1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EPE27138.1 - 1.5e-05 23.9 0.1 1.5e-05 23.9 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EPE27138.1 - 5.2e-05 22.5 0.1 0.00019 20.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EPE27138.1 - 0.00025 20.5 0.1 0.00063 19.2 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EPE27138.1 - 0.0022 18.4 2.6 0.68 10.4 0.1 3.2 3 0 0 3 3 3 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 EPE27138.1 - 0.0023 17.9 0.0 0.0057 16.6 0.0 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 EPE27138.1 - 0.0024 17.2 0.2 0.014 14.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EPE27138.1 - 0.0026 17.1 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AdoHcyase_NAD PF00670.21 EPE27138.1 - 0.0036 17.4 0.8 1.5 8.9 0.2 2.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FMO-like PF00743.19 EPE27138.1 - 0.0059 15.1 0.2 2.4 6.5 0.0 2.2 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.12 EPE27138.1 - 0.0078 15.3 0.2 0.25 10.4 0.1 2.4 3 0 0 3 3 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EPE27138.1 - 0.011 15.0 0.1 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EPE27138.1 - 0.059 12.5 0.1 0.059 12.5 0.1 2.1 3 0 0 3 3 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 EPE27138.1 - 0.084 12.2 0.1 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EPE27138.1 - 0.093 12.4 0.0 0.54 9.9 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EPE27138.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 EPE27138.1 - 0.18 11.4 0.1 0.6 9.7 0.1 1.9 2 0 0 2 2 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain MADF_DNA_bdg PF10545.9 EPE27138.1 - 0.27 11.6 1.1 0.8 10.1 1.1 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Aldedh PF00171.22 EPE27139.1 - 2.7e-138 461.3 0.0 3.4e-138 461.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Epimerase PF01370.21 EPE27140.1 - 2e-16 60.2 0.0 3.4e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EPE27140.1 - 1.1e-10 41.1 0.0 1.5e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 EPE27140.1 - 1.6e-10 40.4 0.0 2.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EPE27140.1 - 1.8e-09 37.5 0.1 8.1e-09 35.3 0.1 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EPE27140.1 - 1.9e-07 31.2 0.0 2.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPE27140.1 - 0.038 13.5 0.1 0.18 11.3 0.1 2.1 2 1 0 2 2 2 0 NmrA-like family DUF3425 PF11905.8 EPE27141.1 - 6.1e-24 84.4 1.3 1e-23 83.7 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EPE27141.1 - 0.039 14.1 12.3 0.25 11.5 12.3 2.1 1 1 0 1 1 1 0 bZIP transcription factor Nic96 PF04097.14 EPE27142.1 - 8.7e-202 671.9 0.0 1.1e-201 671.6 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Y_phosphatase PF00102.27 EPE27143.1 - 1.9e-60 204.4 0.5 6.4e-59 199.4 0.5 2.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 EPE27143.1 - 6.8e-08 33.0 0.0 3.3e-07 30.8 0.0 2.1 3 0 0 3 3 3 1 Rhodanese-like domain DSPc PF00782.20 EPE27143.1 - 0.0076 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EPE27143.1 - 0.028 14.4 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family MFS_1 PF07690.16 EPE27144.1 - 3.9e-39 134.6 25.2 1.2e-37 129.7 22.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 EPE27144.1 - 0.041 13.7 0.1 0.041 13.7 0.1 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF2633 PF11119.8 EPE27144.1 - 0.3 11.0 1.0 0.8 9.7 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) CDC45 PF02724.14 EPE27145.1 - 8.8 4.5 7.2 12 4.0 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Na_Ca_ex PF01699.24 EPE27146.1 - 4.9e-20 72.0 37.7 8.1e-14 51.8 14.3 4.2 5 1 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 EPE27146.1 - 1.8e-15 57.4 12.9 1.8e-15 57.4 12.9 4.8 6 1 0 6 6 6 1 Inner membrane component domain AAA PF00004.29 EPE27147.1 - 7.8e-44 149.3 0.0 1.3e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPE27147.1 - 1.5e-13 50.3 0.0 3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EPE27147.1 - 1.1e-07 31.9 0.0 2.7e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EPE27147.1 - 1.4e-07 31.8 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EPE27147.1 - 2.2e-06 28.2 0.0 0.00011 22.6 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 EPE27147.1 - 1.9e-05 24.5 3.1 5.1e-05 23.1 3.1 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EPE27147.1 - 2.6e-05 24.5 0.2 0.006 16.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EPE27147.1 - 5.6e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EPE27147.1 - 0.00099 18.4 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 EPE27147.1 - 0.001 19.6 0.0 0.019 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EPE27147.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EPE27147.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EPE27147.1 - 0.0035 17.2 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EPE27147.1 - 0.0079 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 EPE27147.1 - 0.0079 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EPE27147.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EPE27147.1 - 0.011 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EPE27147.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EPE27147.1 - 0.022 14.4 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EPE27147.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EPE27147.1 - 0.034 13.6 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 EPE27147.1 - 0.035 14.1 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EPE27147.1 - 0.035 14.5 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EPE27147.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EPE27147.1 - 0.046 13.3 0.1 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain HR1 PF02185.16 EPE27147.1 - 0.051 13.7 0.7 0.13 12.4 0.7 1.6 1 0 0 1 1 1 0 Hr1 repeat Parvo_NS1 PF01057.17 EPE27147.1 - 0.061 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 EPE27147.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2072 PF09845.9 EPE27147.1 - 0.13 12.5 0.1 0.26 11.6 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein FGGY_C PF02782.16 EPE27148.1 - 2.9e-49 167.5 0.4 4.2e-49 167.0 0.4 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EPE27148.1 - 2.9e-21 76.1 0.2 1.9e-18 67.0 0.0 2.9 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain F-box-like PF12937.7 EPE27149.1 - 1.7e-07 31.0 0.0 5.6e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE27149.1 - 1.3e-05 25.0 0.0 2.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain Erythro-docking PF09277.11 EPE27149.1 - 0.013 15.4 0.1 0.035 14.0 0.1 1.8 1 0 0 1 1 1 0 Erythronolide synthase, docking HSF_DNA-bind PF00447.17 EPE27150.1 - 6.7e-30 103.6 0.6 1.2e-29 102.8 0.6 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding adh_short_C2 PF13561.6 EPE27152.1 - 6.4e-44 150.3 0.2 7.6e-43 146.7 0.2 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE27152.1 - 2.7e-38 131.4 0.4 4.4e-38 130.7 0.4 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE27152.1 - 5.7e-10 39.4 0.2 8.8e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 EPE27152.1 - 0.003 17.5 0.1 0.0055 16.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EPE27152.1 - 0.13 11.7 0.1 0.98 8.8 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ATP-grasp_2 PF08442.10 EPE27154.1 - 5.1e-77 258.0 0.9 7.3e-77 257.5 0.2 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EPE27154.1 - 1.2e-26 93.4 1.2 2.5e-26 92.3 0.4 2.0 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 EPE27154.1 - 4.6e-10 39.3 0.1 1e-09 38.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EPE27154.1 - 0.0065 16.3 0.5 0.094 12.5 0.1 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Phage_min_cap2 PF06152.11 EPE27154.1 - 0.61 8.9 2.3 0.47 9.3 0.6 1.6 2 0 0 2 2 2 0 Phage minor capsid protein 2 DUF3245 PF11595.8 EPE27155.1 - 8.2e-08 32.9 7.1 8.2e-08 32.9 7.1 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3245) PMT PF02366.18 EPE27156.1 - 1.4e-84 283.5 15.4 2.8e-84 282.5 15.4 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EPE27156.1 - 2.5e-69 232.9 5.4 2.5e-69 232.9 5.4 2.9 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EPE27156.1 - 5.6e-20 72.0 0.1 8.8e-20 71.3 0.1 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 EPE27156.1 - 0.13 12.5 14.9 0.029 14.6 9.9 2.6 2 1 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Ribonuc_L-PSP PF01042.21 EPE27157.1 - 3.8e-38 130.2 0.0 4.9e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Mito_carr PF00153.27 EPE27159.1 - 3.7e-69 228.7 4.3 5.5e-23 80.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EPE27159.1 - 0.0035 16.6 0.9 1.1 8.3 0.1 3.1 3 0 0 3 3 3 2 Gammaproteobacterial serine protease TauD PF02668.16 EPE27160.1 - 5.4e-47 160.8 1.4 8.5e-47 160.2 1.4 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EPE27160.1 - 1.9e-06 28.4 0.0 4.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 EPE27160.1 - 3.2e-06 26.5 0.1 7.7e-06 25.2 0.1 1.6 1 1 0 1 1 1 1 CsiD Fungal_trans PF04082.18 EPE27161.1 - 2.5e-05 23.4 0.2 8.8e-05 21.7 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain 3Beta_HSD PF01073.19 EPE27162.1 - 7.7e-62 208.8 0.1 3.2e-30 105.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPE27162.1 - 3.5e-25 88.9 0.0 7.8e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE27162.1 - 1.8e-16 60.4 0.0 5.1e-11 42.5 0.0 2.9 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EPE27162.1 - 1.1e-09 37.9 0.0 3.6e-09 36.1 0.0 1.8 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EPE27162.1 - 4.2e-09 35.9 0.4 5e-06 25.9 0.1 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EPE27162.1 - 1.8e-08 33.9 0.0 1.7e-07 30.7 0.1 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EPE27162.1 - 1.5e-07 31.5 0.0 2.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPE27162.1 - 0.0049 16.4 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EPE27162.1 - 0.0073 16.2 0.5 0.24 11.3 0.5 2.4 1 1 0 1 1 1 1 KR domain Glyco_trans_4_2 PF13477.6 EPE27162.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like UQ_con PF00179.26 EPE27163.1 - 1.7e-41 141.1 0.0 6.5e-29 100.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UEV PF05743.13 EPE27163.1 - 0.027 14.3 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 UEV domain Cyt-b5 PF00173.28 EPE27164.1 - 6.3e-18 64.7 1.4 1e-17 64.0 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EPE27164.1 - 4.4e-13 49.7 21.2 4.4e-13 49.7 21.2 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 EPE27164.1 - 0.0078 16.4 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region RRM_1 PF00076.22 EPE27165.1 - 2.2e-41 139.5 0.9 2.2e-19 69.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EPE27165.1 - 3.3e-21 76.2 0.1 1.1e-20 74.5 0.1 2.0 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 EPE27165.1 - 0.00059 19.6 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EPE27165.1 - 0.028 14.5 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif PHM7_cyt PF14703.6 EPE27165.1 - 0.045 14.0 0.1 1.7 8.9 0.1 2.8 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 EPE27165.1 - 0.089 12.4 0.0 0.22 11.1 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPE27165.1 - 0.093 12.9 0.0 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif GAS PF13851.6 EPE27166.1 - 0.00074 18.9 20.0 0.00074 18.9 20.0 1.8 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 EPE27166.1 - 0.036 12.6 20.5 0.06 11.9 20.5 1.3 1 0 0 1 1 1 0 Macoilin family Spc7 PF08317.11 EPE27166.1 - 0.044 12.7 15.1 0.08 11.8 15.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 EPE27166.1 - 0.055 11.0 17.2 0.083 10.4 17.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF948 PF06103.11 EPE27166.1 - 0.098 12.9 6.1 0.14 12.4 0.9 3.3 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) PCEMA1 PF07418.11 EPE27166.1 - 0.12 11.9 4.0 0.23 11.0 4.0 1.4 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Exonuc_VII_L PF02601.15 EPE27166.1 - 0.17 11.4 12.4 0.35 10.4 12.4 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 EPE27166.1 - 0.24 11.5 19.7 0.037 14.1 14.9 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus She9_MDM33 PF05546.11 EPE27166.1 - 0.38 10.5 11.4 0.65 9.8 11.4 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family FliJ PF02050.16 EPE27166.1 - 0.39 11.0 26.0 0.18 12.1 18.9 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein DUF1664 PF07889.12 EPE27166.1 - 0.42 10.7 6.5 0.45 10.6 4.9 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EPE27166.1 - 0.42 10.6 12.6 1.2 9.2 12.6 1.7 1 0 0 1 1 1 0 Laminin Domain II DUF4407 PF14362.6 EPE27166.1 - 0.74 9.1 14.8 1.3 8.3 14.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 EPE27166.1 - 0.79 7.6 9.7 1.3 6.8 9.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PRKG1_interact PF15898.5 EPE27166.1 - 1.3 10.0 20.6 0.82 10.6 17.4 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain ALMT PF11744.8 EPE27166.1 - 1.3 7.8 14.4 0.75 8.6 12.4 1.5 1 1 0 1 1 1 0 Aluminium activated malate transporter FlgN PF05130.12 EPE27166.1 - 1.8 9.1 20.2 3 8.4 0.1 3.0 2 1 0 2 2 2 0 FlgN protein AAA_23 PF13476.6 EPE27166.1 - 1.8 9.0 11.6 1.7 9.1 9.5 2.0 2 0 0 2 2 2 0 AAA domain KELK PF15796.5 EPE27166.1 - 2.3 8.7 17.7 0.37 11.3 13.4 2.0 2 0 0 2 2 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase CENP-H PF05837.12 EPE27166.1 - 2.6 8.5 16.9 0.46 10.9 12.0 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) FapA PF03961.13 EPE27166.1 - 8 4.9 8.4 13 4.2 8.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Prp19 PF08606.11 EPE27166.1 - 8.3 6.5 14.9 0.073 13.1 5.3 2.3 2 0 0 2 2 2 0 Prp19/Pso4-like VWA PF00092.28 EPE27167.1 - 1.9e-08 34.7 0.0 2.9e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Bacteriocin_IIc PF10439.9 EPE27167.1 - 0.096 12.8 1.0 0.18 11.9 1.0 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide VWA_2 PF13519.6 EPE27167.1 - 0.1 13.3 0.0 0.3 11.8 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain zf-C2H2 PF00096.26 EPE27168.1 - 0.0059 17.0 18.3 0.1 13.1 3.3 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE27168.1 - 0.013 16.2 16.5 0.17 12.8 1.6 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EPE27168.1 - 0.096 13.4 0.5 19 5.9 0.0 2.7 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 EPE27168.1 - 0.35 9.3 6.0 0.12 10.9 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) FOXP-CC PF16159.5 EPE27168.1 - 0.45 11.2 2.8 29 5.4 0.2 2.6 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 EPE27168.1 - 1.1 9.6 3.4 16 5.9 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TIM PF00121.18 EPE27170.1 - 6.4e-88 294.2 0.2 7.3e-88 294.0 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase zf-C3HC4_3 PF13920.6 EPE27172.1 - 1.7e-07 31.0 3.5 2.6e-07 30.4 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE27172.1 - 4.4e-07 29.7 7.8 7.8e-07 28.9 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE27172.1 - 6.8e-07 29.0 6.9 1.5e-06 28.0 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE27172.1 - 0.00012 22.3 7.5 0.00023 21.4 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EPE27172.1 - 0.0049 16.8 6.0 0.0099 15.8 6.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EPE27172.1 - 0.0075 16.3 8.3 0.017 15.1 8.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EPE27172.1 - 0.016 15.5 5.3 0.032 14.5 5.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EPE27172.1 - 0.023 14.8 7.3 0.045 13.9 7.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EPE27172.1 - 0.41 10.5 6.9 1.1 9.2 0.2 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EPE27172.1 - 1 9.2 7.1 2.2 8.1 7.1 1.5 1 0 0 1 1 1 0 RING-like zinc finger YdjO PF14169.6 EPE27172.1 - 8.8 6.1 7.9 6.2 6.6 1.6 2.6 1 1 1 2 2 2 0 Cold-inducible protein YdjO Aminotran_1_2 PF00155.21 EPE27174.1 - 1e-63 215.7 0.0 1.5e-63 215.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EPE27174.1 - 0.0067 15.0 0.0 0.016 13.8 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EPE27174.1 - 0.0079 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EPE27174.1 - 0.0087 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EPE27174.1 - 0.089 12.1 0.0 0.38 10.0 0.0 1.8 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AMP-binding PF00501.28 EPE27175.1 - 1e-38 133.1 0.0 1.4e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EPE27175.1 - 0.00029 20.7 0.2 0.029 14.3 0.0 3.0 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus Aminotran_5 PF00266.19 EPE27175.1 - 0.0038 16.2 0.1 0.013 14.5 0.1 1.7 2 0 0 2 2 2 1 Aminotransferase class-V AMP-binding_C PF13193.6 EPE27175.1 - 0.0063 17.5 1.3 0.019 16.0 1.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Protoglobin PF11563.8 EPE27176.1 - 2.4e-38 131.5 0.0 3.1e-18 66.2 0.0 2.0 2 0 0 2 2 2 2 Protoglobin TPT PF03151.16 EPE27177.1 - 2e-57 194.8 14.5 2.4e-57 194.5 14.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EPE27177.1 - 1e-08 35.4 35.9 0.00039 20.6 13.2 3.3 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EPE27177.1 - 2e-05 24.0 16.4 9.1e-05 21.8 16.4 1.9 1 1 0 1 1 1 1 UAA transporter family Wzy_C PF04932.15 EPE27177.1 - 0.017 14.8 3.8 0.62 9.7 0.0 3.1 3 0 0 3 3 3 0 O-Antigen ligase PUNUT PF16913.5 EPE27177.1 - 0.37 10.0 11.4 2.8 7.1 11.1 2.1 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport F-box-like PF12937.7 EPE27178.1 - 0.0018 18.2 0.2 0.0039 17.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like DUF3246 PF11596.8 EPE27178.1 - 0.016 14.7 1.4 0.016 14.7 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) VEFS-Box PF09733.9 EPE27179.1 - 2.9e-13 49.8 0.4 5.9e-13 48.8 0.4 1.4 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Tubulin_C PF03953.17 EPE27179.1 - 0.051 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Tubulin C-terminal domain GH131_N PF18271.1 EPE27181.1 - 4.3e-76 256.0 0.0 5e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Transferase PF02458.15 EPE27182.1 - 5.2e-09 35.3 0.0 2.3e-07 29.8 0.0 2.7 2 1 0 2 2 2 2 Transferase family O-FucT PF10250.9 EPE27183.1 - 1.6e-09 37.9 0.0 5.3e-08 32.9 0.0 2.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF2203 PF09969.9 EPE27185.1 - 0.1 13.4 0.7 0.37 11.5 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) UFD1 PF03152.14 EPE27186.1 - 1.4e-72 242.8 0.0 1.8e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 EPE27186.1 - 0.019 14.8 0.1 0.041 13.7 0.1 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 DUF3748 PF12566.8 EPE27186.1 - 0.12 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) GYF PF02213.16 EPE27187.1 - 4e-11 42.4 1.4 1e-10 41.1 1.4 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EPE27187.1 - 0.11 12.4 0.1 0.31 10.9 0.1 1.8 1 0 0 1 1 1 0 GYF domain 2 Med2 PF11214.8 EPE27187.1 - 0.28 11.4 2.0 0.83 9.8 2.0 1.8 1 1 0 1 1 1 0 Mediator complex subunit 2 TIP49 PF06068.13 EPE27188.1 - 5.4e-119 397.5 1.3 7.5e-119 397.0 1.3 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EPE27188.1 - 3.6e-21 75.1 0.8 1.5e-20 73.1 0.3 2.3 3 0 0 3 3 3 1 TIP49 AAA-lid domain AAA_22 PF13401.6 EPE27188.1 - 0.098 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EPE27189.1 - 1.5e-20 73.7 0.3 1.8e-20 73.4 0.3 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain Lectin_N PF03954.14 EPE27190.1 - 0.019 14.7 0.3 0.019 14.7 0.3 5.8 5 1 1 6 6 6 0 Hepatic lectin, N-terminal domain Shugoshin_N PF07558.11 EPE27190.1 - 0.86 9.5 11.3 0.067 13.1 1.3 4.0 3 1 0 3 3 3 0 Shugoshin N-terminal coiled-coil region PsbP PF01789.16 EPE27190.1 - 1.7 8.8 6.0 0.34 11.1 0.4 2.6 2 1 0 2 2 2 0 PsbP DUF1664 PF07889.12 EPE27190.1 - 2.4 8.2 32.3 0.16 12.0 1.6 6.0 3 2 4 7 7 7 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EPE27190.1 - 3.7 7.7 49.5 0.12 12.5 3.4 6.6 1 1 5 7 7 7 0 Fibrinogen alpha/beta chain family RraB PF06877.11 EPE27190.1 - 8 7.3 7.7 27 5.6 0.4 4.1 3 1 1 4 4 4 0 Regulator of ribonuclease activity B Methyltr_RsmB-F PF01189.17 EPE27191.1 - 6.2e-79 264.3 0.0 9.8e-79 263.6 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EPE27191.1 - 1.7e-07 31.6 0.0 5.9e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF DUF2431 PF10354.9 EPE27191.1 - 0.0048 17.2 0.0 0.0097 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltransf_31 PF13847.6 EPE27191.1 - 0.043 13.6 0.0 0.099 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EPE27191.1 - 0.061 13.4 0.0 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase DUF4717 PF15838.5 EPE27191.1 - 0.23 11.5 2.7 5 7.2 4.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4717) BIRC6 PF12356.8 EPE27191.1 - 0.23 10.9 0.8 0.6 9.5 0.8 1.7 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 Blt1 PF12754.7 EPE27192.1 - 2.6e-34 118.7 0.6 3.4e-34 118.3 0.6 1.1 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 EPE27192.1 - 5.8e-15 54.6 0.2 1e-14 53.8 0.2 1.3 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 EPE27192.1 - 0.0027 17.4 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF3157 PF11355.8 EPE27192.1 - 0.16 11.6 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) Cofilin_ADF PF00241.20 EPE27193.1 - 1.2e-36 125.2 0.2 1.4e-36 124.9 0.2 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein AAA_2 PF07724.14 EPE27194.1 - 4.1e-45 154.0 0.0 1.3e-43 149.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EPE27194.1 - 1.5e-35 121.3 1.2 1.5e-35 121.3 1.2 2.6 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EPE27194.1 - 5.7e-28 96.8 0.3 1.7e-27 95.2 0.3 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EPE27194.1 - 6.6e-18 65.4 0.0 5.2e-09 36.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EPE27194.1 - 1.3e-12 47.9 0.0 6e-08 32.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPE27194.1 - 3.3e-11 43.9 0.6 0.00012 22.5 0.1 3.5 2 2 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 EPE27194.1 - 5.5e-08 32.7 0.2 8.3e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 EPE27194.1 - 7.4e-08 32.8 0.0 0.027 14.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EPE27194.1 - 4.1e-05 23.2 0.0 0.19 11.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 EPE27194.1 - 4.5e-05 23.5 1.9 1.4 8.7 0.0 4.2 3 2 1 4 4 4 1 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EPE27194.1 - 4.6e-05 23.2 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 EPE27194.1 - 5.4e-05 23.2 0.1 0.19 11.7 0.0 2.4 2 0 0 2 2 2 2 NACHT domain TniB PF05621.11 EPE27194.1 - 5.9e-05 22.5 0.0 0.046 13.1 0.0 3.6 3 1 0 3 3 2 1 Bacterial TniB protein AAA_14 PF13173.6 EPE27194.1 - 0.00027 21.0 0.0 0.66 10.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EPE27194.1 - 0.0011 18.7 0.0 0.43 10.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EPE27194.1 - 0.0012 19.4 2.9 1.5 9.4 0.0 4.0 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 EPE27194.1 - 0.0016 18.8 0.0 0.77 10.2 0.0 2.7 2 1 0 2 2 2 1 RNA helicase TsaE PF02367.17 EPE27194.1 - 0.0026 17.7 0.0 3.7 7.6 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EPE27194.1 - 0.0028 17.9 0.2 1.2 9.4 0.0 3.6 3 1 0 3 3 3 1 AAA domain SRP54 PF00448.22 EPE27194.1 - 0.0036 16.9 0.0 0.35 10.5 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EPE27194.1 - 0.0046 16.7 0.2 0.19 11.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EPE27194.1 - 0.0054 17.1 0.5 0.31 11.4 0.1 3.1 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 EPE27194.1 - 0.0075 16.5 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 EPE27194.1 - 0.0093 15.4 0.3 5.5 6.3 0.0 3.3 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EPE27194.1 - 0.013 14.7 0.1 1.7 7.8 0.1 3.4 3 2 0 3 3 3 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 EPE27194.1 - 0.013 15.4 0.0 5.2 7.0 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 EPE27194.1 - 0.014 15.9 1.4 3.7 8.1 0.0 3.3 3 0 0 3 3 3 0 ABC transporter ERM PF00769.19 EPE27194.1 - 0.021 14.6 11.6 0.041 13.7 11.6 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Zeta_toxin PF06414.12 EPE27194.1 - 0.023 14.0 0.0 1.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.15 EPE27194.1 - 0.031 14.3 0.0 6.7 6.7 0.0 2.9 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 EPE27194.1 - 0.036 14.0 0.0 0.5 10.3 0.0 2.4 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 EPE27194.1 - 0.047 13.4 0.0 2.1 8.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 EPE27194.1 - 0.048 13.8 0.0 19 5.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EPE27194.1 - 0.048 13.1 0.0 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ATP_bind_1 PF03029.17 EPE27194.1 - 0.063 13.0 0.0 0.71 9.6 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PIF1 PF05970.14 EPE27194.1 - 0.067 12.3 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_6 PF12774.7 EPE27194.1 - 0.18 10.7 0.0 4.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region DUF87 PF01935.17 EPE27194.1 - 0.33 11.0 1.8 25 4.9 0.0 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain OEP PF02321.18 EPE27194.1 - 1.2 9.0 5.7 2.2 8.1 5.7 1.4 1 0 0 1 1 1 0 Outer membrane efflux protein DUF1640 PF07798.11 EPE27194.1 - 1.2 9.2 7.1 2.4 8.2 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Atg14 PF10186.9 EPE27194.1 - 1.5 7.8 7.7 2.6 7.1 7.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 EPE27194.1 - 4.1 7.4 18.1 6 6.9 14.6 2.6 2 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4094 PF13334.6 EPE27194.1 - 7.1 7.1 6.9 5.8 7.4 0.4 3.3 2 1 1 3 3 2 0 Domain of unknown function (DUF4094) EMP24_GP25L PF01105.24 EPE27195.1 - 1.2e-48 165.5 0.0 1.4e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Arf PF00025.21 EPE27196.1 - 3.2e-79 264.4 0.1 3.7e-79 264.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EPE27196.1 - 1.4e-14 54.3 0.0 1.9e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EPE27196.1 - 1.5e-14 53.8 0.0 1.8e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EPE27196.1 - 1.8e-13 50.4 1.2 1.5e-09 37.5 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EPE27196.1 - 4.4e-13 49.2 0.0 4.8e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EPE27196.1 - 1.3e-10 41.0 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EPE27196.1 - 3.6e-06 27.1 0.0 5.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EPE27196.1 - 0.0093 15.3 0.8 0.027 13.8 0.8 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase TPM_phosphatase PF04536.14 EPE27196.1 - 0.11 12.7 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 TPM domain GST_C PF00043.25 EPE27197.1 - 2.1e-10 40.7 1.5 4e-10 39.8 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EPE27197.1 - 1.5e-09 38.0 0.0 4.7e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPE27197.1 - 7.1e-07 29.4 0.0 1.4e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPE27197.1 - 3.7e-06 27.2 0.0 7.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPE27197.1 - 0.00011 22.2 0.4 0.00034 20.6 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPE27197.1 - 0.00014 21.9 0.1 0.00042 20.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF4771 PF15995.5 EPE27197.1 - 0.037 14.3 0.3 0.54 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4771) CUTL PF16557.5 EPE27197.1 - 0.065 13.4 0.5 0.14 12.4 0.5 1.5 1 0 0 1 1 1 0 CUT1-like DNA-binding domain of SATB Lactamase_B_2 PF12706.7 EPE27198.1 - 8.3e-29 100.5 0.0 2.3e-27 95.9 0.0 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EPE27198.1 - 6.4e-11 42.4 0.0 1.6e-10 41.1 0.0 1.7 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EPE27198.1 - 0.0036 17.3 2.9 0.014 15.4 1.6 2.5 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily RRM_1 PF00076.22 EPE27199.1 - 4.4e-20 71.3 0.1 5.2e-11 42.2 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPE27199.1 - 0.00027 20.7 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 2 Occluded RNA-recognition motif Ndc80_HEC PF03801.13 EPE27200.1 - 1.3e-58 197.0 0.1 2.8e-58 195.9 0.1 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family TPR_MLP1_2 PF07926.12 EPE27200.1 - 0.00097 19.2 15.6 0.00097 19.2 15.6 3.9 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein Filament PF00038.21 EPE27200.1 - 0.0028 17.3 41.0 0.16 11.5 13.4 2.3 2 0 0 2 2 2 2 Intermediate filament protein FliJ PF02050.16 EPE27200.1 - 0.0056 16.9 4.7 0.0056 16.9 4.7 3.6 2 2 1 3 3 3 1 Flagellar FliJ protein DHR10 PF18595.1 EPE27200.1 - 0.25 11.4 43.2 0.064 13.3 15.9 3.8 2 2 1 3 3 3 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 EPE27200.1 - 0.51 9.2 42.1 0.28 10.0 16.4 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF1366 PF07104.11 EPE27200.1 - 1.2 8.8 13.6 4.7 6.9 3.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) NPV_P10 PF05531.12 EPE27200.1 - 2.1 8.8 10.0 8.9 6.9 0.8 4.2 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 EPE27200.1 - 2.4 7.6 19.6 0.8 9.2 5.4 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit IFT57 PF10498.9 EPE27200.1 - 3.7 6.4 30.6 0.71 8.8 7.7 3.2 3 1 0 3 3 3 0 Intra-flagellar transport protein 57 Tropomyosin PF00261.20 EPE27200.1 - 4.1 6.7 51.9 2 7.7 17.3 3.2 2 1 1 3 3 3 0 Tropomyosin Pex14_N PF04695.13 EPE27201.1 - 6.8e-38 130.8 1.7 6.8e-38 130.8 1.7 3.3 2 2 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C4H2 PF10146.9 EPE27201.1 - 0.00038 20.8 2.1 0.00038 20.8 2.1 2.0 2 0 0 2 2 2 1 Zinc finger-containing protein Golgin_A5 PF09787.9 EPE27201.1 - 0.0045 16.5 8.0 0.0067 15.9 8.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF3450 PF11932.8 EPE27201.1 - 0.011 15.1 8.2 0.017 14.4 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Lebercilin PF15619.6 EPE27201.1 - 0.013 15.1 10.0 0.021 14.5 10.0 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease SlyX PF04102.12 EPE27201.1 - 0.015 15.9 4.2 0.027 15.1 1.7 2.7 2 1 0 2 2 2 0 SlyX HBM PF16591.5 EPE27201.1 - 0.03 13.7 4.8 0.042 13.3 4.3 1.5 1 1 0 1 1 1 0 Helical bimodular sensor domain SYCE1 PF15233.6 EPE27201.1 - 0.04 14.0 8.4 0.065 13.3 8.4 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF1043 PF06295.12 EPE27201.1 - 0.055 13.5 6.5 0.25 11.4 6.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3584 PF12128.8 EPE27201.1 - 0.065 10.8 9.4 0.087 10.3 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1978 PF09321.10 EPE27201.1 - 0.08 12.2 3.4 0.11 11.8 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) LMBR1 PF04791.16 EPE27201.1 - 0.15 11.0 0.2 0.19 10.6 0.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HSD3 PF15244.6 EPE27201.1 - 0.18 11.3 6.4 0.27 10.7 6.4 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 YscO PF07321.12 EPE27201.1 - 0.31 11.0 7.4 0.56 10.2 7.4 1.5 1 0 0 1 1 1 0 Type III secretion protein YscO Baculo_PEP_C PF04513.12 EPE27201.1 - 0.65 10.0 6.2 12 6.0 0.2 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-SNARE PF05008.15 EPE27201.1 - 0.97 9.8 7.2 10 6.6 5.6 2.5 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus YabA PF06156.13 EPE27201.1 - 1.6 9.4 3.4 2 9.1 1.6 2.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF572 PF04502.13 EPE27201.1 - 2.8 7.5 10.0 3.9 7.0 10.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Spectrin PF00435.21 EPE27201.1 - 3.9 8.0 8.3 6.7 7.3 5.8 2.2 1 1 1 2 2 2 0 Spectrin repeat Abhydrolase_3 PF07859.13 EPE27202.1 - 1.1e-42 146.3 0.1 7.5e-42 143.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EPE27202.1 - 7.6e-05 21.7 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase HMG_CoA_synt_C PF08540.10 EPE27203.1 - 6.4e-106 354.1 0.5 8.5e-106 353.7 0.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EPE27203.1 - 2.6e-97 323.7 0.4 4.2e-97 323.1 0.4 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal RRM_1 PF00076.22 EPE27204.1 - 5.1e-23 80.7 0.0 6.5e-23 80.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPE27204.1 - 0.00073 19.6 0.0 0.0011 19.1 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif PAP_PilO PF06864.12 EPE27204.1 - 0.088 11.6 0.0 0.11 11.4 0.0 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) ChaC PF04752.12 EPE27205.1 - 5e-52 176.6 0.1 1.9e-51 174.7 0.1 1.8 1 1 0 1 1 1 1 ChaC-like protein DUF4120 PF13496.6 EPE27205.1 - 0.089 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4120) EF-hand_1 PF00036.32 EPE27206.1 - 1.7e-14 52.2 1.1 4.6e-06 25.8 0.1 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EPE27206.1 - 1.1e-13 50.7 0.5 3.1e-09 36.5 0.0 2.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EPE27206.1 - 4.8e-10 38.6 0.6 0.014 15.3 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EPE27206.1 - 4.9e-09 35.3 1.7 0.016 14.7 0.0 4.2 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 EPE27206.1 - 7.5e-09 35.9 0.0 4.9e-05 23.7 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair Myb_DNA-binding PF00249.31 EPE27209.1 - 4.1e-24 84.5 1.7 2.2e-13 50.2 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPE27209.1 - 2.1e-16 59.9 0.5 2.1e-12 47.1 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.8 EPE27209.1 - 0.05 13.8 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) SLIDE PF09111.10 EPE27209.1 - 0.073 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 SLIDE Sigma70_r4_2 PF08281.12 EPE27209.1 - 0.17 11.6 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Glyco_transf_41 PF13844.6 EPE27210.1 - 1.8e-100 336.6 0.0 1.4e-51 175.4 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 EPE27210.1 - 3e-15 55.3 6.2 0.00023 20.8 0.0 5.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EPE27210.1 - 1.2e-13 50.0 8.6 0.0055 16.7 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EPE27210.1 - 2.4e-12 46.3 12.4 0.00022 20.8 0.1 6.2 4 1 2 6 6 6 4 TPR repeat TPR_8 PF13181.6 EPE27210.1 - 8e-12 44.4 3.6 0.0078 16.4 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPE27210.1 - 3.4e-11 43.3 6.4 0.011 15.9 0.2 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EPE27210.1 - 1.8e-10 40.3 5.8 0.0094 15.8 0.5 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EPE27210.1 - 8.8e-09 34.8 2.2 0.0009 19.1 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPE27210.1 - 1.4e-08 34.5 2.7 0.26 11.7 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPE27210.1 - 2.1e-06 28.1 6.5 0.024 15.1 0.1 3.9 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EPE27210.1 - 9.1e-06 26.2 3.8 0.00096 19.8 0.1 4.1 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EPE27210.1 - 2.7e-05 24.6 11.8 0.00047 20.8 0.3 5.8 4 2 2 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.17 EPE27210.1 - 0.012 16.1 0.3 0.18 12.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 EPE27210.1 - 0.015 15.5 2.2 0.32 11.2 1.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EPE27210.1 - 0.062 12.5 0.4 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec23_trunk PF04811.15 EPE27211.1 - 2.6e-80 269.5 0.0 4e-80 268.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EPE27211.1 - 2.8e-30 104.9 0.3 6.1e-30 103.8 0.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EPE27211.1 - 2.7e-25 88.2 0.1 6.4e-25 87.0 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Ribosomal_L11_N PF03946.14 EPE27211.1 - 2.8e-21 75.1 1.8 3e-21 75.0 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EPE27211.1 - 1.6e-14 54.1 0.3 3.5e-14 53.1 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Gelsolin PF00626.22 EPE27211.1 - 4.1e-11 42.6 0.0 9.6e-11 41.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 EPE27211.1 - 7.9e-07 29.0 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 EPE27211.1 - 0.052 13.0 0.7 0.12 11.8 0.1 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Aa_trans PF01490.18 EPE27212.1 - 7.1e-41 140.3 38.0 8.5e-41 140.0 38.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EPE27212.1 - 3.7e-06 26.2 22.8 7.1e-06 25.3 22.8 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DCP1 PF06058.13 EPE27213.1 - 1.5e-27 95.9 0.0 2e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family Vps39_2 PF10367.9 EPE27214.1 - 7.6e-07 29.6 0.0 2.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EPE27214.1 - 0.00039 20.7 0.0 0.018 15.3 0.0 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 EPE27214.1 - 0.0021 18.0 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS CASP_C PF08172.12 EPE27215.1 - 8.9e-94 313.5 1.5 8.9e-94 313.5 1.5 3.3 3 1 1 4 4 4 1 CASP C terminal Cep57_MT_bd PF06657.13 EPE27215.1 - 0.21 12.1 30.9 0.057 13.9 2.4 5.9 6 1 1 7 7 7 0 Centrosome microtubule-binding domain of Cep57 Lzipper-MIP1 PF14389.6 EPE27215.1 - 0.41 11.0 15.7 4.5 7.6 1.7 4.6 4 1 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 TolA_bind_tri PF16331.5 EPE27215.1 - 0.68 10.1 28.7 2.2 8.4 6.9 5.1 5 0 0 5 5 4 0 TolA binding protein trimerisation SlyX PF04102.12 EPE27215.1 - 0.95 10.1 0.0 0.95 10.1 0.0 5.9 7 0 0 7 7 6 0 SlyX YabA PF06156.13 EPE27215.1 - 1.6 9.4 25.7 1.7 9.3 0.1 5.8 4 2 0 5 5 5 0 Initiation control protein YabA Fib_alpha PF08702.10 EPE27215.1 - 3 8.0 25.9 2.5 8.3 0.6 4.4 5 0 0 5 5 5 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 EPE27215.1 - 4.3 7.4 55.6 0.8 9.8 4.9 7.1 5 1 1 6 6 6 0 TPR/MLP1/MLP2-like protein SKA1 PF07160.12 EPE27215.1 - 4.3 7.1 21.1 3.3 7.5 0.6 4.2 3 1 1 4 4 4 0 Spindle and kinetochore-associated protein 1 LemA PF04011.12 EPE27215.1 - 7 6.5 10.2 2.5 8.0 0.4 3.5 3 1 1 4 4 4 0 LemA family Seadorna_VP6 PF07407.11 EPE27215.1 - 9.3 5.1 5.5 3.2 6.6 0.6 2.2 2 0 0 2 2 2 0 Seadornavirus VP6 protein DUF3455 PF11937.8 EPE27216.1 - 7.8e-49 166.1 0.2 1.1e-48 165.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 EPE27216.1 - 1.4 9.2 9.4 0.23 11.6 2.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2990) Mis12 PF05859.12 EPE27217.1 - 1e-45 155.1 0.1 1.5e-45 154.6 0.1 1.3 1 0 0 1 1 1 1 Mis12 protein DUF3580 PF12117.8 EPE27217.1 - 0.027 14.7 0.2 0.073 13.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3580) PPR_2 PF13041.6 EPE27218.1 - 3.3e-34 116.8 0.0 1.5e-09 37.9 0.0 7.8 6 2 2 8 8 8 7 PPR repeat family PPR_3 PF13812.6 EPE27218.1 - 7e-19 67.7 0.0 0.00053 20.0 0.0 6.0 2 2 5 8 8 8 7 Pentatricopeptide repeat domain PPR PF01535.20 EPE27218.1 - 3.4e-14 52.0 0.1 0.13 12.5 0.1 7.8 9 0 0 9 9 9 4 PPR repeat PPR_1 PF12854.7 EPE27218.1 - 3.8e-13 48.9 0.0 0.00068 19.3 0.0 6.7 7 0 0 7 7 7 4 PPR repeat PPR_long PF17177.4 EPE27218.1 - 2e-09 37.1 0.0 0.00077 18.9 0.0 3.3 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP IQCJ-SCHIP1 PF15157.6 EPE27218.1 - 0.19 11.6 0.0 7.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif KRE1 PF17056.5 EPE27219.1 - 2.7e-08 33.4 2.8 2.7e-08 33.4 0.9 1.9 2 1 0 2 2 2 1 Killer toxin-resistance protein 1 FAD_binding_3 PF01494.19 EPE27220.1 - 1.1e-05 24.8 0.3 0.00047 19.5 0.0 2.6 3 0 0 3 3 3 2 FAD binding domain SE PF08491.10 EPE27220.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Metal_resist PF13801.6 EPE27220.1 - 0.077 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Heavy-metal resistance DEAD PF00270.29 EPE27221.1 - 1.4e-46 158.5 0.0 2.4e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE27221.1 - 1.6e-22 80.0 0.0 1.2e-21 77.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EPE27221.1 - 6.8e-20 71.1 0.3 1.8e-19 69.7 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EPE27221.1 - 8e-05 22.7 0.5 0.00021 21.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EPE27221.1 - 0.065 12.9 0.2 0.33 10.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain FRG2 PF15315.6 EPE27221.1 - 6.4 6.9 9.1 11 6.2 9.1 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 SRAP PF02586.14 EPE27222.1 - 5.6e-84 281.1 0.1 9.6e-84 280.3 0.1 1.4 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Cellulase PF00150.18 EPE27223.1 - 1.7e-48 165.5 0.0 2.2e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_6 PF01341.17 EPE27224.1 - 8.1e-107 357.5 0.6 1e-106 357.2 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 EPE27224.1 - 3.1e-08 33.4 9.0 3.1e-08 33.4 9.0 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_61 PF03443.14 EPE27225.1 - 9.7e-46 156.3 0.0 1.1e-45 156.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PHtD_u1 PF16645.5 EPE27225.1 - 0.15 12.6 1.0 0.27 11.7 1.0 1.4 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein Glyco_hydro_61 PF03443.14 EPE27226.1 - 2.7e-60 203.8 0.0 3.2e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Helicase_C_3 PF13625.6 EPE27226.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Med1 PF10744.9 EPE27227.1 - 4.7e-106 355.3 0.0 5.7e-106 355.0 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 IKBKB_SDD PF18397.1 EPE27228.1 - 0.11 11.7 0.6 7.9 5.7 0.0 2.2 2 0 0 2 2 2 0 IQBAL scaffold dimerization domain AIM24 PF01987.17 EPE27230.1 - 3.2e-54 183.8 0.2 3.9e-54 183.5 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Ndc1_Nup PF09531.10 EPE27230.1 - 0.0073 15.0 2.0 0.0076 15.0 2.0 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup eIF-5_eIF-2B PF01873.17 EPE27231.1 - 4.7e-42 142.6 0.3 8.2e-42 141.8 0.3 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Osteopontin PF00865.18 EPE27231.1 - 0.041 13.4 13.0 0.91 9.0 7.1 2.2 1 1 1 2 2 2 0 Osteopontin TF_Zn_Ribbon PF08271.12 EPE27231.1 - 0.072 12.6 0.7 0.19 11.3 0.7 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding GET2 PF08690.10 EPE27231.1 - 0.26 10.9 6.2 0.4 10.3 6.2 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 zf-HYPF PF07503.12 EPE27231.1 - 0.42 10.4 5.2 15 5.4 4.7 2.8 2 1 1 3 3 3 0 HypF finger Arc_trans_TRASH PF08394.10 EPE27231.1 - 1.6 9.1 6.7 1.8 9.0 0.2 2.8 1 1 1 2 2 2 0 Archaeal TRASH domain MARVEL PF01284.23 EPE27233.1 - 1.5e-27 96.4 13.0 1.8e-27 96.2 13.0 1.0 1 0 0 1 1 1 1 Membrane-associating domain UbiA PF01040.18 EPE27234.1 - 9.9e-44 149.5 20.7 1.3e-43 149.1 20.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family JmjC PF02373.22 EPE27235.1 - 2.2e-08 34.5 0.2 6.8e-08 32.9 0.2 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 EPE27235.1 - 3.9e-08 33.4 10.6 3.9e-08 33.4 10.6 2.6 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 EPE27235.1 - 0.038 13.7 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Peptidase_M4_C PF02868.15 EPE27235.1 - 0.17 11.7 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain TMEM239 PF15841.5 EPE27236.1 - 0.062 13.2 5.0 0.1 12.5 5.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 239 family DUF805 PF05656.14 EPE27236.1 - 0.37 11.2 2.9 1 9.8 3.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF1772 PF08592.11 EPE27237.1 - 0.00059 20.2 1.4 0.0018 18.6 0.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) EthD PF07110.11 EPE27238.1 - 0.00061 20.9 0.3 0.00094 20.3 0.3 1.4 1 1 0 1 1 1 1 EthD domain Glyco_hydro_16 PF00722.21 EPE27239.1 - 2.4e-12 46.7 0.3 5e-12 45.7 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EPE27239.1 - 1.9e-05 23.3 1.0 0.074 11.5 0.1 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) PS_Dcarbxylase PF02666.15 EPE27240.1 - 2.4e-55 187.2 0.0 3.6e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EPE27240.1 - 1.8e-37 127.8 0.0 1.2e-18 67.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 EPE27240.1 - 0.0026 17.2 0.0 0.0095 15.4 0.0 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EPE27240.1 - 0.0056 16.5 0.2 0.084 12.8 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EPE27240.1 - 0.02 14.4 0.0 0.064 12.8 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EPE27240.1 - 0.059 13.8 1.2 0.14 12.6 0.2 2.1 2 0 0 2 2 2 0 EF-hand domain pair HAD PF12710.7 EPE27241.1 - 2.1e-22 80.5 0.0 3.5e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EPE27241.1 - 0.00037 20.0 0.0 0.00089 18.7 0.0 1.5 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 EPE27241.1 - 0.033 13.7 0.0 0.082 12.4 0.0 1.7 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 EPE27241.1 - 0.066 13.5 0.2 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EPE27244.1 - 9.1e-19 67.8 0.0 2.1e-18 66.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE27244.1 - 1.1e-09 37.9 0.0 1.3e-08 34.5 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Fungal_trans_2 PF11951.8 EPE27245.1 - 6.9e-07 28.4 0.2 1.5e-06 27.3 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE27245.1 - 0.00019 21.5 5.6 0.00019 21.5 5.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.6 EPE27245.1 - 0.1 12.9 0.3 0.6 10.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2681 PF10883.8 EPE27246.1 - 0.96 9.9 2.0 2.2 8.7 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) APH PF01636.23 EPE27247.1 - 3.4e-12 46.8 0.0 4.6e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE27247.1 - 0.00021 21.0 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EPE27247.1 - 0.053 12.5 0.1 0.1 11.5 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain EcKinase PF02958.20 EPE27247.1 - 0.06 12.6 0.0 0.086 12.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase C1_1 PF00130.22 EPE27248.1 - 0.038 13.9 0.8 0.056 13.3 0.8 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3509 PF12021.8 EPE27248.1 - 0.14 12.0 0.1 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) Ank_2 PF12796.7 EPE27249.1 - 6.4e-16 58.7 4.0 8.7e-06 26.2 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE27249.1 - 5.5e-13 49.2 0.2 5.2e-06 26.9 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EPE27249.1 - 5.7e-13 48.7 2.1 0.0047 17.3 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EPE27249.1 - 1.2e-11 43.7 1.0 0.03 14.8 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EPE27249.1 - 9.3e-09 35.4 2.0 0.0054 17.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 EPE27249.1 - 2.1e-06 27.6 0.2 1.3e-05 25.0 0.2 2.2 1 1 0 1 1 1 1 KilA-N domain FbpA PF05833.11 EPE27249.1 - 0.001 18.0 3.5 0.0017 17.2 3.5 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DNA_repr_REX1B PF14966.6 EPE27249.1 - 0.28 11.9 4.2 1.7 9.4 3.0 2.6 2 0 0 2 2 2 0 DNA repair REX1-B DUF4482 PF14818.6 EPE27249.1 - 6.8 7.6 10.1 1.8 9.4 6.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Sugar_tr PF00083.24 EPE27250.1 - 1.5e-86 291.1 20.7 1.7e-85 287.6 20.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE27250.1 - 1.4e-33 116.4 31.1 1.1e-32 113.4 25.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FixQ PF05545.11 EPE27250.1 - 0.43 10.6 2.3 0.53 10.3 0.1 2.4 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Pkinase PF00069.25 EPE27251.1 - 1.7e-63 214.5 0.0 2.2e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE27251.1 - 2.6e-29 102.3 0.0 4.3e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE27251.1 - 0.035 13.4 0.0 0.083 12.2 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 EPE27251.1 - 0.045 13.7 0.0 0.17 11.7 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Arf PF00025.21 EPE27252.1 - 3.9e-74 247.9 0.1 4.5e-74 247.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EPE27252.1 - 2.1e-14 53.8 0.0 2.9e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EPE27252.1 - 3.8e-12 46.0 2.4 3e-08 33.2 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EPE27252.1 - 1.2e-11 44.5 0.0 1.3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EPE27252.1 - 1.8e-11 43.8 0.0 2.2e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EPE27252.1 - 1.7e-10 40.7 0.0 2.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EPE27252.1 - 0.00012 22.2 0.1 0.00033 20.7 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EPE27252.1 - 0.023 14.0 0.3 0.047 13.0 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF1325 PF07039.11 EPE27253.1 - 1.1e-26 93.5 0.0 2.6e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain Hamartin PF04388.12 EPE27253.1 - 0.77 8.4 5.7 0.89 8.1 5.7 1.2 1 0 0 1 1 1 0 Hamartin protein PMI_typeI PF01238.21 EPE27254.1 - 1.6e-144 481.8 0.1 1.8e-144 481.5 0.1 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Ribosomal_S15 PF00312.22 EPE27254.1 - 0.066 13.4 0.0 0.39 11.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S15 RraB PF06877.11 EPE27254.1 - 0.13 13.0 0.4 0.96 10.2 0.1 2.4 2 0 0 2 2 2 0 Regulator of ribonuclease activity B Fungal_trans_2 PF11951.8 EPE27255.1 - 4.6e-15 55.3 0.0 2.3e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.11 EPE27256.1 - 6e-25 88.3 0.1 1.4e-24 87.1 0.1 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans_2 PF11951.8 EPE27257.1 - 4.1e-07 29.2 1.1 5.4e-07 28.8 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE27257.1 - 0.00016 21.7 1.2 0.00031 20.8 1.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored_FMN PF00724.20 EPE27258.1 - 2.9e-46 158.3 0.0 3.6e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GTP_cyclohydro2 PF00925.20 EPE27259.1 - 1.1e-61 207.2 0.0 1.5e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II AA_permease_2 PF13520.6 EPE27260.1 - 6.2e-66 223.0 48.4 7.3e-66 222.7 48.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE27260.1 - 5.5e-17 61.5 44.9 6.7e-17 61.2 44.9 1.0 1 0 0 1 1 1 1 Amino acid permease HET PF06985.11 EPE27261.1 - 9.6e-21 74.7 0.0 1.8e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.18 EPE27262.1 - 2.7e-06 27.4 7.0 6e-06 26.3 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE27262.1 - 0.037 13.1 0.2 0.07 12.2 0.2 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF3328 PF11807.8 EPE27263.1 - 5e-18 65.7 9.4 4e-17 62.7 9.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) NifW PF03206.14 EPE27263.1 - 0.24 12.0 0.7 0.5 10.9 0.7 1.4 1 0 0 1 1 1 0 Nitrogen fixation protein NifW HET PF06985.11 EPE27264.1 - 6.4e-35 120.6 4.5 1.6e-34 119.3 4.5 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NAD_binding_10 PF13460.6 EPE27265.1 - 1.4e-09 38.1 0.0 1.4e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EPE27265.1 - 2e-09 37.4 0.0 1.4e-08 34.6 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EPE27265.1 - 0.0007 19.9 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EPE27265.1 - 0.002 18.2 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ADH_zinc_N_2 PF13602.6 EPE27265.1 - 0.058 14.4 0.0 0.15 13.1 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase CFEM PF05730.11 EPE27267.1 - 0.023 14.8 9.7 0.054 13.6 9.7 1.6 1 1 0 1 1 1 0 CFEM domain Rax2 PF12768.7 EPE27267.1 - 0.044 13.2 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Acyl-CoA_dh_1 PF00441.24 EPE27268.1 - 1.2e-22 80.7 0.3 1.2e-22 80.7 0.3 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EPE27268.1 - 2.4e-07 30.8 0.0 6.2e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EPE27268.1 - 2.5e-07 31.3 0.0 4.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EPE27268.1 - 8.7e-07 29.3 2.2 1.6e-06 28.4 2.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DEAD PF00270.29 EPE27272.1 - 2.7e-33 115.2 0.0 4.5e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE27272.1 - 2.2e-24 85.9 0.0 4.9e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE27272.1 - 0.00034 20.7 0.0 0.00052 20.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EPE27272.1 - 0.026 14.3 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain FCH PF00611.23 EPE27273.1 - 4.1e-27 94.3 1.1 1.1e-26 93.0 0.1 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 EPE27273.1 - 5e-21 74.3 1.0 1.4e-13 50.4 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EPE27273.1 - 2.1e-15 56.0 0.3 1.8e-07 30.6 0.1 2.5 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 EPE27273.1 - 2.6e-15 56.0 5.6 4.1e-15 55.4 5.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.11 EPE27273.1 - 9.8e-05 22.6 1.3 0.042 14.1 0.5 2.6 2 0 0 2 2 2 2 Bacterial SH3 domain C1_2 PF03107.16 EPE27273.1 - 0.00083 19.6 1.6 0.0015 18.8 1.6 1.4 1 0 0 1 1 1 1 C1 domain SH3_10 PF17902.1 EPE27273.1 - 0.0038 17.3 0.0 0.18 11.9 0.0 2.6 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EPE27273.1 - 0.007 16.0 0.1 2.1 8.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain Allexi_40kDa PF05549.11 EPE27273.1 - 0.031 13.8 0.4 0.13 11.7 0.0 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein PilJ PF13675.6 EPE27273.1 - 0.05 13.6 1.7 0.076 13.0 0.4 2.0 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term COG2 PF06148.11 EPE27273.1 - 0.31 11.1 5.3 0.38 10.9 1.9 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BCDHK_Adom3 PF10436.9 EPE27274.1 - 3.9e-75 251.1 0.0 5.9e-75 250.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EPE27274.1 - 5.8e-13 49.3 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EPE27274.1 - 0.038 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase E2_bind PF08825.10 EPE27274.1 - 0.11 12.7 0.1 0.35 11.1 0.1 1.9 1 0 0 1 1 1 0 E2 binding domain DUF5463 PF17551.2 EPE27275.1 - 4.7 7.2 5.2 9.8 6.2 0.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5463) FAP PF07174.11 EPE27280.1 - 2 7.8 15.4 2.5 7.5 15.4 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF3984 PF13136.6 EPE27280.1 - 3 7.2 9.1 3.8 6.8 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) XRN_M PF17846.1 EPE27284.1 - 0.013 14.5 0.7 0.019 13.9 0.7 1.2 1 0 0 1 1 1 0 Xrn1 helical domain YqgF PF14639.6 EPE27284.1 - 0.1 12.3 0.4 0.22 11.3 0.4 1.5 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Adeno_terminal PF02459.15 EPE27284.1 - 0.12 10.7 3.9 0.17 10.2 3.9 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein PBP1_TM PF14812.6 EPE27284.1 - 2.9 8.3 9.9 0.24 11.8 5.1 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_72 PF03198.14 EPE27286.1 - 3.6e-133 443.7 0.1 4.4e-133 443.4 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EPE27286.1 - 0.00018 21.0 0.1 0.00085 18.8 0.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EPE27286.1 - 0.031 13.4 0.1 0.16 11.1 0.1 1.9 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Pyridoxal_deC PF00282.19 EPE27288.1 - 4.8e-15 55.2 0.0 7.7e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EPE27288.1 - 6.7e-07 28.6 0.0 1.9e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EPE27288.1 - 0.043 13.1 0.0 0.066 12.5 0.0 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_transf_34 PF05637.12 EPE27289.1 - 8.1e-71 238.5 0.0 9.7e-71 238.3 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 EPE27289.1 - 0.076 12.6 0.0 0.28 10.7 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF273 PMI_typeI PF01238.21 EPE27290.1 - 8e-74 249.1 0.0 5.9e-72 242.9 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 EPE27290.1 - 8.6e-05 22.5 0.0 0.0055 16.6 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 EPE27290.1 - 0.00013 21.6 0.1 0.23 11.2 0.1 2.4 2 0 0 2 2 2 2 Cupin domain RINGv PF12906.7 EPE27291.1 - 5.6e-10 39.2 5.2 1.8e-09 37.6 1.8 2.3 2 0 0 2 2 2 1 RING-variant domain PHD_4 PF16866.5 EPE27291.1 - 0.0028 17.7 4.9 0.32 11.1 2.1 2.4 2 0 0 2 2 2 2 PHD-finger zf-RING_2 PF13639.6 EPE27291.1 - 0.027 14.8 5.5 0.63 10.4 2.2 2.3 2 0 0 2 2 2 0 Ring finger domain Proteasome PF00227.26 EPE27292.1 - 1.1e-57 194.6 0.0 2.3e-33 115.3 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EPE27292.1 - 9e-11 41.2 0.1 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RCC1_2 PF13540.6 EPE27293.1 - 1.4e-11 43.8 0.0 0.0064 16.3 0.0 4.0 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EPE27293.1 - 6.7e-10 39.4 6.3 0.001 19.6 0.1 5.3 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat HSP70 PF00012.20 EPE27294.1 - 4.9e-11 41.5 0.0 1.6e-09 36.6 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein FtsA PF14450.6 EPE27294.1 - 0.0031 17.9 0.0 0.045 14.2 0.0 2.4 2 0 0 2 2 2 1 Cell division protein FtsA DUF4201 PF13870.6 EPE27296.1 - 0.00024 20.9 6.9 0.00041 20.1 6.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Lebercilin PF15619.6 EPE27296.1 - 0.0084 15.8 10.5 0.011 15.4 5.2 2.3 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 EPE27296.1 - 0.0086 15.0 9.0 0.014 14.3 9.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Gp58 PF07902.11 EPE27296.1 - 0.022 13.1 2.9 0.03 12.6 2.9 1.1 1 0 0 1 1 1 0 gp58-like protein Dynamin_M PF01031.20 EPE27296.1 - 0.022 14.0 0.9 0.6 9.3 0.4 2.2 2 0 0 2 2 2 0 Dynamin central region OmpH PF03938.14 EPE27296.1 - 0.18 12.1 3.7 0.32 11.3 3.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Tup_N PF08581.10 EPE27296.1 - 0.29 11.5 6.3 0.29 11.5 1.0 2.8 2 1 0 2 2 2 0 Tup N-terminal Golgin_A5 PF09787.9 EPE27296.1 - 0.33 10.4 11.6 0.21 11.0 8.4 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 TMF_TATA_bd PF12325.8 EPE27296.1 - 0.33 11.2 11.7 0.16 12.2 1.4 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Uso1_p115_C PF04871.13 EPE27296.1 - 1.2 9.5 8.5 3.3 8.1 8.5 1.7 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region SlyX PF04102.12 EPE27296.1 - 1.3 9.7 3.8 36 5.1 2.5 3.1 2 1 0 2 2 2 0 SlyX FliT PF05400.13 EPE27296.1 - 1.5 9.7 6.2 0.99 10.3 0.1 2.9 3 1 0 3 3 3 0 Flagellar protein FliT ADIP PF11559.8 EPE27296.1 - 7.4 6.6 10.2 9.3 6.3 8.9 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Sec2p PF06428.11 EPE27296.1 - 8.9 6.4 9.9 13 5.8 7.4 2.4 3 1 0 3 3 2 0 GDP/GTP exchange factor Sec2p Hpt PF01627.23 EPE27297.1 - 7.7e-13 48.5 0.0 1.2e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Hpt domain DUF3216 PF11505.8 EPE27297.1 - 0.39 10.9 4.0 9.3 6.5 0.9 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3216) AKAP7_NLS PF10469.9 EPE27299.1 - 1.8e-26 93.3 0.0 2e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 EPE27299.1 - 0.0059 16.5 0.0 0.0078 16.1 0.0 1.4 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Ribonuclease_3 PF00636.26 EPE27300.1 - 4.6e-38 130.1 0.0 3.8e-20 72.5 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 EPE27300.1 - 4.6e-23 81.2 0.0 1.5e-22 79.5 0.0 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 EPE27300.1 - 3.6e-19 69.2 0.0 1.3e-07 31.8 0.0 3.7 3 1 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.31 EPE27300.1 - 5e-16 59.0 0.2 1.5e-15 57.5 0.2 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPE27300.1 - 5.4e-07 29.6 0.1 3.3e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EPE27300.1 - 0.0014 18.7 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.15 EPE27300.1 - 0.092 12.4 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 Mito_fiss_reg PF05308.11 EPE27300.1 - 0.26 11.4 2.3 1.2 9.2 1.4 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Pkinase PF00069.25 EPE27301.1 - 1.3e-54 185.3 0.0 2e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE27301.1 - 1.9e-32 112.6 0.0 6.3e-31 107.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EPE27301.1 - 0.0047 15.9 0.0 0.0074 15.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EPE27301.1 - 0.043 12.8 0.0 0.063 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stc1 PF12898.7 EPE27302.1 - 2.8e-11 43.8 11.4 6.6e-11 42.6 11.4 1.7 1 0 0 1 1 1 1 Stc1 domain Peptidase_M60 PF13402.6 EPE27304.1 - 0.053 13.0 2.2 0.7 9.4 0.1 3.0 1 1 2 3 3 3 0 Peptidase M60, enhancin and enhancin-like Chorismate_bind PF00425.18 EPE27305.1 - 1.9e-88 296.4 0.0 1e-86 290.7 0.0 2.1 2 0 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.13 EPE27305.1 - 7e-26 91.1 0.1 4.5e-23 82.0 0.0 3.5 2 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region AAA_32 PF13654.6 EPE27306.1 - 0.0046 15.8 5.1 0.0055 15.6 5.1 1.2 1 0 0 1 1 1 1 AAA domain CPSF100_C PF13299.6 EPE27306.1 - 0.18 12.0 2.5 0.14 12.3 1.1 1.5 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal BLOC1_2 PF10046.9 EPE27306.1 - 0.97 9.8 8.0 4 7.8 2.6 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FOXP-CC PF16159.5 EPE27306.1 - 1.1 9.9 3.0 1.7 9.3 0.1 2.5 2 1 1 3 3 3 0 FOXP coiled-coil domain DUF2381 PF09544.10 EPE27306.1 - 1.5 8.3 5.2 9.2 5.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2381) DUF4446 PF14584.6 EPE27306.1 - 1.7 8.6 5.2 2 8.4 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Zn_clus PF00172.18 EPE27307.1 - 5.5e-08 32.8 7.0 9.5e-08 32.0 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE27307.1 - 5.7e-05 22.1 0.3 0.0001 21.2 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 EPE27308.1 - 1e-96 324.6 26.6 1.3e-96 324.3 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE27308.1 - 2.5e-21 76.0 53.8 2.1e-19 69.7 25.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mannosyl_trans PF05007.13 EPE27310.1 - 0.051 13.4 0.2 0.051 13.4 0.2 2.2 2 1 0 2 2 2 0 Mannosyltransferase (PIG-M) Virul_fac_BrkB PF03631.15 EPE27310.1 - 0.055 13.1 7.4 0.018 14.6 4.0 1.7 2 0 0 2 2 2 0 Virulence factor BrkB Orf78 PF06024.12 EPE27310.1 - 0.16 12.3 0.3 16 5.8 0.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) Amastin PF07344.11 EPE27310.1 - 0.38 10.6 7.5 0.16 11.8 4.5 1.8 2 0 0 2 2 2 0 Amastin surface glycoprotein DUF4064 PF13273.6 EPE27310.1 - 0.94 9.8 10.1 2.3 8.5 2.7 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF4131 PF13567.6 EPE27310.1 - 2.6 7.6 4.8 3.9 7.1 1.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF2721 PF11026.8 EPE27310.1 - 3.5 7.5 13.1 1.2 9.0 3.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF2569 PF10754.9 EPE27310.1 - 6.6 7.2 15.0 5.8 7.4 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) PRA1 PF03208.19 EPE27310.1 - 8.4 6.0 8.3 3.1 7.4 3.8 2.2 1 1 2 3 3 3 0 PRA1 family protein Rrn6 PF10214.9 EPE27311.1 - 2.7e-144 482.7 8.7 3.4e-144 482.4 8.7 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 EPE27312.1 - 1.7e-25 89.0 0.3 6e-25 87.2 0.3 2.0 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 RYDR_ITPR PF01365.21 EPE27312.1 - 0.027 13.9 2.3 0.049 13.0 2.3 1.4 1 0 0 1 1 1 0 RIH domain Atg14 PF10186.9 EPE27312.1 - 0.27 10.3 8.3 0.47 9.5 8.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3698 PF12479.8 EPE27312.1 - 2 9.0 7.0 16 6.1 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3698) TMPIT PF07851.13 EPE27312.1 - 3.5 6.8 11.7 5.8 6.1 11.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein MOZART1 PF12554.8 EPE27313.1 - 1e-24 86.0 0.4 1.3e-24 85.7 0.4 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated XPC-binding PF09280.11 EPE27313.1 - 0.053 13.3 0.1 0.94 9.3 0.0 2.2 2 1 0 2 2 2 0 XPC-binding domain GFA PF04828.14 EPE27314.1 - 3.5e-14 52.9 1.7 5.9e-14 52.2 1.7 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cytochrom_C PF00034.21 EPE27316.1 - 4.2e-10 40.6 0.0 7.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EPE27316.1 - 5.1e-07 29.9 1.8 2.9e-06 27.5 1.8 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EPE27316.1 - 0.00039 20.1 0.5 0.0024 17.6 0.5 2.0 1 1 0 1 1 1 1 Cytochrome c-550 domain LSM PF01423.22 EPE27318.1 - 1.3e-14 53.7 0.0 1.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain NUDIX PF00293.28 EPE27319.1 - 3.4e-17 62.7 0.6 4.7e-17 62.3 0.6 1.2 1 0 0 1 1 1 1 NUDIX domain ATE_C PF04377.15 EPE27321.1 - 1.7e-48 164.6 0.3 3e-48 163.9 0.3 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus adh_short PF00106.25 EPE27322.1 - 9.4e-19 67.6 0.5 6.1e-16 58.4 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE27322.1 - 1.5e-11 44.3 0.2 2.9e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE27322.1 - 5.1e-08 33.0 0.2 8.5e-08 32.3 0.2 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EPE27322.1 - 0.043 13.6 0.1 0.099 12.4 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RNase_PH PF01138.21 EPE27323.1 - 6.2e-14 52.6 0.0 1.4e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EPE27323.1 - 0.0053 16.8 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 SOG2 PF10428.9 EPE27325.1 - 0.0017 17.6 6.7 0.0022 17.3 6.7 1.0 1 0 0 1 1 1 1 RAM signalling pathway protein CDC27 PF09507.10 EPE27325.1 - 1 8.7 9.9 1.5 8.2 9.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hamartin PF04388.12 EPE27325.1 - 5.1 5.6 9.1 5.7 5.5 9.1 1.0 1 0 0 1 1 1 0 Hamartin protein Lipase_GDSL_2 PF13472.6 EPE27326.1 - 5.6e-13 49.7 0.5 6.9e-13 49.4 0.5 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE27326.1 - 2.5e-05 24.3 0.3 3.6e-05 23.8 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TRP PF06011.12 EPE27327.1 - 4e-173 576.0 32.2 4.9e-173 575.8 32.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EPE27327.1 - 1.4e-42 145.3 1.0 2.6e-42 144.5 1.0 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 EPE27327.1 - 0.1 13.1 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 ML domain DUF2721 PF11026.8 EPE27327.1 - 0.16 11.9 0.1 0.16 11.9 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) VirB3 PF05101.13 EPE27327.1 - 2.7 8.3 11.5 2 8.7 0.5 3.5 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein 4HBT PF03061.22 EPE27328.1 - 0.00098 19.4 0.5 0.045 14.1 0.1 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Snf7 PF03357.21 EPE27329.1 - 7.4e-24 84.3 14.8 7.6e-19 68.0 6.4 2.2 1 1 1 2 2 2 2 Snf7 AAA PF00004.29 EPE27330.1 - 2.2e-90 299.9 0.0 7.6e-46 155.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPE27330.1 - 1.9e-17 62.8 1.9 1.4e-07 31.2 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EPE27330.1 - 2.5e-14 53.3 0.0 1.1e-05 25.3 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EPE27330.1 - 3e-13 50.5 0.1 0.0002 21.8 0.0 4.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 EPE27330.1 - 3.5e-10 40.2 0.0 0.0013 18.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EPE27330.1 - 4.7e-10 39.6 0.4 0.0012 18.9 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EPE27330.1 - 1.7e-09 38.0 0.0 0.0019 18.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EPE27330.1 - 2e-09 37.8 0.3 0.02 15.2 0.0 4.3 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 EPE27330.1 - 3.1e-08 33.2 0.1 0.002 17.4 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EPE27330.1 - 5.8e-08 32.8 0.0 0.0097 15.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EPE27330.1 - 2e-07 31.3 0.0 0.015 15.7 0.0 2.7 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 EPE27330.1 - 2.7e-07 30.5 0.0 0.017 14.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 EPE27330.1 - 3.4e-07 29.9 0.2 0.03 13.7 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EPE27330.1 - 1.2e-06 28.1 0.6 0.014 14.8 0.0 3.6 4 0 0 4 4 3 2 KaiC Zeta_toxin PF06414.12 EPE27330.1 - 1.2e-06 27.9 0.1 0.045 13.0 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_25 PF13481.6 EPE27330.1 - 1.5e-06 27.9 1.2 0.91 9.1 0.0 4.3 3 1 1 4 4 4 2 AAA domain AAA_3 PF07726.11 EPE27330.1 - 1.6e-06 28.0 0.0 0.048 13.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 EPE27330.1 - 3.6e-06 27.2 0.0 0.021 14.9 0.0 2.6 2 0 0 2 2 2 2 Cytidylate kinase-like family Rad17 PF03215.15 EPE27330.1 - 4e-06 26.9 0.0 0.051 13.5 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain NACHT PF05729.12 EPE27330.1 - 6e-06 26.3 0.2 0.12 12.2 0.0 3.3 2 1 1 3 3 3 2 NACHT domain AAA_28 PF13521.6 EPE27330.1 - 6.3e-06 26.5 0.0 0.089 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EPE27330.1 - 7.8e-06 26.5 0.0 0.24 12.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EPE27330.1 - 9.9e-06 25.2 0.0 0.068 12.7 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 EPE27330.1 - 1.9e-05 24.6 0.0 0.32 11.0 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EPE27330.1 - 3.5e-05 24.3 0.0 0.15 12.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.26 EPE27330.1 - 4.7e-05 23.1 0.0 0.19 11.4 0.0 3.3 4 0 0 4 4 3 1 Sigma-54 interaction domain TniB PF05621.11 EPE27330.1 - 0.0002 20.8 0.0 0.24 10.8 0.0 3.6 3 1 0 4 4 3 1 Bacterial TniB protein AAA_11 PF13086.6 EPE27330.1 - 0.00031 20.6 0.8 1.2 8.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 EPE27330.1 - 0.00043 20.1 0.0 0.35 10.6 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activ_2 PF14532.6 EPE27330.1 - 0.00051 20.2 0.0 0.47 10.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.13 EPE27330.1 - 0.00055 19.2 0.0 0.023 13.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AFG1_ATPase PF03969.16 EPE27330.1 - 0.0006 18.8 0.0 0.2 10.5 0.0 2.5 2 0 0 2 2 2 1 AFG1-like ATPase AAA_17 PF13207.6 EPE27330.1 - 0.00075 19.9 0.9 2.2 8.7 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_24 PF13479.6 EPE27330.1 - 0.00089 19.0 0.0 0.83 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EPE27330.1 - 0.0009 18.5 0.0 0.8 8.8 0.0 2.7 3 0 0 3 3 2 1 NB-ARC domain ATPase_2 PF01637.18 EPE27330.1 - 0.0009 19.2 0.4 1.5 8.7 0.0 3.7 3 2 1 4 4 4 1 ATPase domain predominantly from Archaea PhoH PF02562.16 EPE27330.1 - 0.0023 17.4 0.3 2.2 7.7 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein Parvo_NS1 PF01057.17 EPE27330.1 - 0.0026 16.9 0.1 1.5 7.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 SKI PF01202.22 EPE27330.1 - 0.0032 17.6 0.0 3.6 7.7 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase AAA_19 PF13245.6 EPE27330.1 - 0.0062 16.9 0.1 3.2 8.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EPE27330.1 - 0.031 13.5 0.1 3.2 6.9 0.0 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.12 EPE27330.1 - 0.039 13.8 0.0 3 7.6 0.0 3.0 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 EPE27330.1 - 0.045 13.8 0.0 15 5.5 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit SRPRB PF09439.10 EPE27330.1 - 0.094 12.1 0.1 12 5.3 0.0 3.2 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Bac_DnaA PF00308.18 EPE27330.1 - 0.11 12.3 0.0 3 7.6 0.0 2.5 2 1 0 2 2 2 0 Bacterial dnaA protein NTPase_1 PF03266.15 EPE27330.1 - 0.12 12.2 0.8 6.4 6.7 0.0 3.0 3 0 0 3 3 2 0 NTPase AAA_30 PF13604.6 EPE27330.1 - 0.14 11.9 0.4 16 5.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EPE27330.1 - 0.16 11.7 0.3 39 3.9 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase AAA_23 PF13476.6 EPE27330.1 - 5.6 7.4 5.9 7.7 7.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF2293 PF10056.9 EPE27331.1 - 3.9e-33 113.5 0.1 2e-32 111.3 0.1 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) Mito_carr PF00153.27 EPE27332.1 - 3.5e-40 135.8 9.0 1.3e-16 60.3 0.3 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein zinc_ribbon_6 PF14599.6 EPE27334.1 - 9.5e-25 86.4 0.7 9.5e-25 86.4 0.7 3.9 3 0 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.12 EPE27334.1 - 1e-18 67.6 19.7 1e-18 67.6 19.7 3.7 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EPE27334.1 - 6.9e-07 29.5 9.6 6.9e-07 29.5 9.6 5.6 3 2 2 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPE27334.1 - 0.00024 20.9 8.5 0.00024 20.9 8.5 5.5 4 2 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) Translin PF01997.16 EPE27335.1 - 2.3e-51 174.7 0.0 2.9e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Translin family Phage_int_SAM_1 PF02899.17 EPE27335.1 - 0.11 12.8 0.2 8.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Peroxidase_2 PF01328.17 EPE27336.1 - 3.8e-43 148.2 0.0 5.1e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 SCP2 PF02036.17 EPE27338.1 - 3.3e-25 88.5 0.5 4.2e-25 88.2 0.5 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EPE27338.1 - 3.2e-05 24.2 0.1 4.6e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 EPE27338.1 - 0.0052 17.2 0.0 0.0068 16.8 0.0 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain Ran_BP1 PF00638.18 EPE27339.1 - 1.8e-13 50.8 0.1 5.5e-13 49.3 0.1 1.9 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 EPE27339.1 - 0.0018 19.1 22.9 0.0018 19.1 22.9 16.7 4 4 10 14 14 14 5 Nucleoporin FG repeat region DUF2040 PF09745.9 EPE27339.1 - 0.0091 16.1 15.2 0.28 11.2 5.3 2.5 2 0 0 2 2 2 2 Coiled-coil domain-containing protein 55 (DUF2040) Neuraminidase PF18413.1 EPE27339.1 - 0.068 12.8 0.0 0.24 11.0 0.0 1.9 1 0 0 1 1 1 0 Neuraminidase-like domain ERK-JNK_inhib PF15002.6 EPE27339.1 - 0.16 11.6 4.0 3.7 7.2 0.2 2.3 2 0 0 2 2 2 0 ERK and JNK pathways, inhibitor DUF287 PF03384.14 EPE27339.1 - 1.2 9.6 9.3 7.8 7.0 1.3 2.4 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 DUF572 PF04502.13 EPE27340.1 - 0.058 13.0 5.2 0.063 12.9 5.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CDC45 PF02724.14 EPE27340.1 - 0.074 11.3 9.0 0.081 11.2 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Pes-10 PF07149.11 EPE27340.1 - 0.54 9.2 10.1 0.7 8.9 10.1 1.1 1 0 0 1 1 1 0 Pes-10 DNA_pol_phi PF04931.13 EPE27340.1 - 0.98 7.4 11.9 1.2 7.2 11.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Hid1 PF12722.7 EPE27340.1 - 1.8 6.6 3.4 2.1 6.4 3.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM176 PF14851.6 EPE27340.1 - 2.4 7.8 9.5 4.6 6.9 9.5 1.5 1 1 0 1 1 1 0 FAM176 family RRN3 PF05327.11 EPE27340.1 - 4 5.9 10.0 4.9 5.6 10.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 EPE27340.1 - 8 5.7 10.2 11 5.3 10.2 1.2 1 0 0 1 1 1 0 NOA36 protein CBP_BcsN PF17038.5 EPE27343.1 - 0.063 12.6 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN FTA4 PF13093.6 EPE27344.1 - 2.4e-51 174.5 0.0 2.8e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Sugar_tr PF00083.24 EPE27345.1 - 7e-63 213.1 26.6 8.3e-63 212.8 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE27345.1 - 1.5e-13 50.4 52.2 4.6e-10 38.9 22.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Hexapep PF00132.24 EPE27346.1 - 2.1e-08 33.6 10.1 2.7e-05 23.7 3.0 4.5 3 1 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EPE27346.1 - 0.016 14.9 6.6 0.027 14.2 0.2 3.3 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EPE27346.1 - 0.026 13.5 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase F-box-like PF12937.7 EPE27347.1 - 1.9e-08 34.1 0.0 6.8e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EPE27347.1 - 0.025 14.5 4.1 0.031 14.2 1.9 2.4 2 1 0 2 2 2 0 F-box domain Phage_min_tail PF05939.13 EPE27348.1 - 0.15 12.5 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Phage minor tail protein LIM PF00412.22 EPE27349.1 - 8.1e-24 83.6 18.8 1.9e-12 47.2 4.9 2.3 2 0 0 2 2 2 2 LIM domain C1_1 PF00130.22 EPE27349.1 - 1.8 8.5 13.7 5.3 7.0 2.9 3.0 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NAD_binding_5 PF07994.12 EPE27350.1 - 3.9e-144 479.9 0.1 4.7e-144 479.7 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EPE27350.1 - 7.8e-46 154.8 0.3 3.2e-45 152.8 0.2 2.1 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase DUF3489 PF11994.8 EPE27350.1 - 0.025 14.6 0.2 0.24 11.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3489) tRNA_anti-codon PF01336.25 EPE27351.1 - 0.034 14.1 0.0 3.3 7.8 0.0 2.5 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Metallophos_2 PF12850.7 EPE27352.1 - 4.5e-13 49.7 0.0 5.7e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Catalase PF00199.19 EPE27353.1 - 3.1e-153 510.4 0.0 5e-153 509.7 0.0 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EPE27353.1 - 5.6e-13 48.9 0.1 1.1e-12 47.9 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive NmrA PF05368.13 EPE27354.1 - 1.3e-07 31.4 0.0 3.4e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EPE27354.1 - 0.0002 21.3 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding PAC2 PF09754.9 EPE27354.1 - 0.059 13.4 0.0 0.26 11.3 0.0 2.0 1 1 0 2 2 2 0 PAC2 family Hemerythrin PF01814.23 EPE27355.1 - 5.2e-12 46.5 1.3 7.8e-12 45.9 1.3 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Cgr1 PF03879.14 EPE27355.1 - 0.14 12.6 2.6 0.37 11.2 0.1 2.3 3 0 0 3 3 3 0 Cgr1 family GFA PF04828.14 EPE27356.1 - 7.8e-13 48.6 0.0 9.3e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme KGG PF10685.9 EPE27357.1 - 2.5e-30 103.8 12.8 5e-10 39.3 1.1 3.3 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Phage_holin_2_4 PF16082.5 EPE27357.1 - 0.0028 17.4 7.7 0.32 10.8 0.6 2.7 3 0 0 3 3 3 2 Bacteriophage holin family, superfamily II-like Ribosomal_S5_C PF03719.15 EPE27357.1 - 0.14 11.7 3.9 6.8 6.2 0.1 2.5 3 0 0 3 3 3 0 Ribosomal protein S5, C-terminal domain DUF3618 PF12277.8 EPE27357.1 - 0.14 12.4 0.0 58 4.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) K_channel_TID PF07941.11 EPE27357.1 - 0.99 9.9 16.1 3.4 8.2 4.4 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Myosin_N PF02736.19 EPE27358.1 - 0.13 12.1 0.2 0.29 11.0 0.1 1.6 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain DUF1664 PF07889.12 EPE27360.1 - 0.1 12.7 3.3 1.1 9.3 1.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CDO_I PF05995.12 EPE27364.1 - 2.4e-36 124.6 0.0 3e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 EPE27364.1 - 0.0043 16.5 0.2 0.0082 15.6 0.2 1.6 1 1 0 1 1 1 1 PCO_ADO Glyco_hydro_115 PF15979.5 EPE27366.1 - 2e-139 464.8 2.1 2e-139 464.8 2.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 EPE27366.1 - 7.2e-10 39.0 0.0 2.2e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain HTH_ABP1_N PF18107.1 EPE27366.1 - 0.14 11.9 0.2 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain Abhydrolase_6 PF12697.7 EPE27367.1 - 7.3e-10 39.8 1.3 1.5e-09 38.8 1.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE27367.1 - 0.00055 19.6 0.1 0.0011 18.6 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DnaB_2 PF07261.11 EPE27367.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Replication initiation and membrane attachment MFS_1 PF07690.16 EPE27368.1 - 1.3e-25 90.1 26.3 1.3e-25 90.1 26.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE27368.1 - 6.5e-11 41.8 3.5 6.5e-11 41.8 3.5 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter UNC-93 PF05978.16 EPE27368.1 - 0.04 13.6 0.6 0.04 13.6 0.6 1.8 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 EPE27369.1 - 3.7e-95 319.4 16.8 4.4e-95 319.2 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE27369.1 - 8.6e-37 126.9 34.5 1.9e-32 112.6 19.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5413 PF17434.2 EPE27369.1 - 4.8 7.5 10.3 0.22 11.8 3.0 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5413) DUF4538 PF15061.6 EPE27369.1 - 8.1 6.3 8.4 4.1 7.2 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) Peptidase_C1_2 PF03051.15 EPE27370.1 - 9.5e-154 512.4 0.0 1.1e-153 512.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EPE27370.1 - 1.4e-06 28.5 0.0 0.0092 16.1 0.1 2.6 3 0 0 3 3 3 2 Papain family cysteine protease SnoaL_4 PF13577.6 EPE27370.1 - 0.072 13.2 0.5 0.17 12.0 0.5 1.5 1 0 0 1 1 1 0 SnoaL-like domain Choline_sulf_C PF12411.8 EPE27370.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal Y_phosphatase3 PF13350.6 EPE27371.1 - 7.1e-46 157.0 0.0 8e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EPE27371.1 - 0.013 15.0 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EPE27371.1 - 0.046 13.3 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF4444 PF14563.6 EPE27371.1 - 0.13 11.9 0.4 14 5.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4444) FAD_binding_3 PF01494.19 EPE27372.1 - 1.2e-65 222.1 0.0 1.5e-65 221.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EPE27372.1 - 1.7e-49 168.1 0.0 2.8e-49 167.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain PSI_PsaE PF02427.17 EPE27372.1 - 0.053 13.2 0.8 12 5.7 0.0 2.8 3 0 0 3 3 3 0 Photosystem I reaction centre subunit IV / PsaE SE PF08491.10 EPE27372.1 - 0.12 11.5 0.0 0.34 9.9 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase PKD PF00801.20 EPE27372.1 - 0.13 12.2 0.0 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 PKD domain RNase_T PF00929.24 EPE27374.1 - 0.039 14.5 0.0 0.047 14.2 0.0 1.1 1 0 0 1 1 1 0 Exonuclease Asparaginase_2 PF01112.18 EPE27375.1 - 2.8e-64 217.1 0.1 3.6e-64 216.7 0.1 1.0 1 0 0 1 1 1 1 Asparaginase DUF374 PF04028.13 EPE27375.1 - 0.047 13.3 0.1 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Peptidase_M43 PF05572.13 EPE27376.1 - 1.1e-13 51.3 0.0 2e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EPE27376.1 - 5.4e-08 33.2 0.0 9.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EPE27376.1 - 0.00012 22.6 0.0 0.00021 21.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EPE27376.1 - 0.0032 17.4 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EPE27376.1 - 0.007 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 EPE27376.1 - 0.018 14.3 0.1 0.028 13.7 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Epimerase PF01370.21 EPE27376.1 - 0.03 13.8 0.1 0.048 13.1 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_M66 PF10462.9 EPE27376.1 - 0.052 12.5 0.4 0.083 11.8 0.4 1.2 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 EPE27376.1 - 0.089 11.4 1.0 0.13 10.8 1.0 1.1 1 0 0 1 1 1 0 Putative peptidase family adh_short PF00106.25 EPE27377.1 - 1.5e-21 76.8 0.0 2.5e-18 66.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EPE27377.1 - 1.6e-07 31.4 0.0 3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE27377.1 - 5e-05 22.6 0.0 7.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EPE27377.1 - 0.00019 21.0 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Clr5 PF14420.6 EPE27378.1 - 5.9e-10 39.2 5.1 5.9e-10 39.2 5.1 2.2 2 0 0 2 2 2 1 Clr5 domain FabA PF07977.13 EPE27378.1 - 0.024 14.2 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 FabA-like domain zf-H2C2_2 PF13465.6 EPE27378.1 - 0.065 13.7 0.3 10 6.7 0.0 3.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPE27378.1 - 0.088 13.7 10.6 7.1 7.8 0.4 4.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EPE27378.1 - 3.3 8.4 18.3 4.6 7.9 0.3 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type TF_Otx PF03529.13 EPE27379.1 - 1.8 9.0 3.8 0.7 10.3 0.3 2.0 2 0 0 2 2 2 0 Otx1 transcription factor SNase PF00565.17 EPE27383.1 - 1.2e-70 234.9 0.9 6.9e-23 81.2 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EPE27383.1 - 2e-23 82.7 0.0 3.8e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 EPE27383.1 - 9.9e-05 21.7 1.6 0.0004 19.7 0.0 2.5 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) Sod_Cu PF00080.20 EPE27384.1 - 9e-45 152.3 6.1 1.1e-44 152.0 6.1 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) MR_MLE_C PF13378.6 EPE27385.1 - 9.5e-43 146.3 0.0 1.3e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EPE27385.1 - 1.4e-09 38.2 0.0 2.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short_C2 PF13561.6 EPE27386.1 - 1.7e-56 191.4 0.1 2.2e-56 191.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE27386.1 - 5.7e-43 146.7 0.1 8.6e-43 146.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE27386.1 - 2.3e-09 37.4 0.6 3.3e-09 36.9 0.6 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EPE27386.1 - 0.0011 18.2 0.0 0.0013 17.9 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EPE27386.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Phage_Gp23 PF10669.9 EPE27387.1 - 0.58 10.5 5.7 0.92 9.9 5.7 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) RTA1 PF04479.13 EPE27388.1 - 1.3e-55 188.2 18.1 1.8e-55 187.7 18.1 1.2 1 0 0 1 1 1 1 RTA1 like protein LHC PF00556.20 EPE27388.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.7 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit DUF4690 PF15756.5 EPE27388.1 - 0.19 12.4 0.1 0.4 11.3 0.1 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage RNase_H PF00075.24 EPE27391.1 - 6.4e-10 39.4 0.0 9.5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 RNase H DAO PF01266.24 EPE27392.1 - 2.4e-40 139.2 0.2 2.8e-40 139.0 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EPE27392.1 - 5.2e-06 25.9 0.0 1.4e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EPE27392.1 - 2.7e-05 23.5 0.5 0.00035 19.8 0.5 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EPE27392.1 - 0.0077 15.5 0.0 0.63 9.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE27392.1 - 0.0093 16.2 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE27392.1 - 0.03 13.6 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPE27392.1 - 0.039 13.9 0.1 0.32 11.0 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EPE27392.1 - 0.1 11.6 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ADPrib_exo_Tox PF03496.14 EPE27392.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme OPT PF03169.15 EPE27393.1 - 3.5e-178 594.1 60.1 4e-178 593.9 60.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2953 PF11167.8 EPE27393.1 - 0.018 15.1 0.2 0.061 13.4 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) Gag_spuma PF03276.14 EPE27393.1 - 0.032 12.7 0.2 0.058 11.8 0.2 1.3 1 0 0 1 1 1 0 Spumavirus gag protein Memo PF01875.17 EPE27394.1 - 2.4e-71 240.1 0.0 2.8e-71 239.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Fungal_trans_2 PF11951.8 EPE27395.1 - 0.00041 19.3 5.1 0.0016 17.3 2.1 2.7 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE27395.1 - 0.0078 16.3 2.8 0.012 15.7 2.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3_C PF01915.22 EPE27396.1 - 1.8e-51 175.0 0.0 3.2e-51 174.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE27396.1 - 6e-34 117.9 0.0 1.1e-33 117.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE27396.1 - 9.1e-23 80.2 0.4 1.6e-22 79.4 0.4 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4982 PF16355.5 EPE27397.1 - 0.1 12.5 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) COG2 PF06148.11 EPE27398.1 - 0.0069 16.5 6.4 0.23 11.6 0.2 3.3 2 1 2 4 4 4 2 COG (conserved oligomeric Golgi) complex component, COG2 CdvA PF18822.1 EPE27398.1 - 0.021 14.7 3.1 0.028 14.2 1.7 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain SKA2 PF16740.5 EPE27398.1 - 0.032 14.0 2.0 0.088 12.6 1.1 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Filament PF00038.21 EPE27398.1 - 0.049 13.2 2.2 0.14 11.7 1.8 1.9 2 0 0 2 2 2 0 Intermediate filament protein DUF3877 PF12993.7 EPE27398.1 - 0.11 12.4 0.3 0.45 10.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) GldM_N PF12081.8 EPE27398.1 - 0.23 11.5 7.9 0.5 10.4 3.2 2.3 2 0 0 2 2 2 0 GldM N-terminal domain DUF1664 PF07889.12 EPE27398.1 - 0.24 11.5 3.4 2.1 8.4 0.4 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 EPE27398.1 - 0.34 11.2 3.4 1.4 9.2 3.3 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.12 EPE27398.1 - 0.35 10.9 4.0 0.48 10.5 1.8 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ApoLp-III PF07464.11 EPE27398.1 - 0.38 10.8 4.9 0.62 10.1 0.7 3.0 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Lectin_N PF03954.14 EPE27398.1 - 2.9 7.6 5.4 2.7 7.8 0.3 2.6 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain HrpB7 PF09486.10 EPE27398.1 - 4.9 7.5 7.3 0.23 11.8 1.0 2.0 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Pkinase PF00069.25 EPE27400.1 - 1.8e-08 34.1 0.0 2.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EPE27400.1 - 0.0045 16.4 0.1 0.0066 15.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EPE27400.1 - 0.0083 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EPE27400.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EPE27400.1 - 0.036 14.0 0.6 0.052 13.5 0.6 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HTH_ABP1_N PF18107.1 EPE27401.1 - 1.9e-23 81.9 0.2 4.2e-23 80.8 0.2 1.6 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain DUF3425 PF11905.8 EPE27401.1 - 6e-17 61.8 0.1 1.7e-16 60.3 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) HTH_Tnp_Tc5 PF03221.16 EPE27401.1 - 1.4e-12 47.4 0.5 6.7e-12 45.3 0.5 2.2 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain adh_short PF00106.25 EPE27402.1 - 7.3e-26 90.8 0.3 9.9e-25 87.1 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE27402.1 - 4.8e-17 62.3 0.1 1.1e-15 57.9 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EPE27402.1 - 0.0025 17.3 1.1 0.008 15.7 0.9 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EPE27402.1 - 0.0055 16.6 0.8 0.012 15.5 0.8 1.8 1 1 0 1 1 1 1 KR domain UPF0258 PF06789.12 EPE27402.1 - 0.11 12.6 0.0 13 5.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) MFS_1 PF07690.16 EPE27403.1 - 4.9e-15 55.3 19.0 8.6e-15 54.5 19.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 EPE27403.1 - 0.014 13.3 0.0 0.02 12.8 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TauD PF02668.16 EPE27404.1 - 2.8e-44 151.9 0.0 3.6e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Syja_N PF02383.18 EPE27405.1 - 6.7e-93 311.5 0.1 8.7e-93 311.1 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain HR1 PF02185.16 EPE27405.1 - 0.14 12.3 1.1 0.32 11.1 1.1 1.5 1 0 0 1 1 1 0 Hr1 repeat Ras PF00071.22 EPE27406.1 - 3.8e-59 198.9 0.4 4.3e-59 198.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE27406.1 - 2.4e-36 124.6 0.3 4.1e-36 123.8 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE27406.1 - 1e-15 57.6 0.1 1.3e-15 57.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EPE27406.1 - 1e-07 31.6 0.1 1.2e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EPE27406.1 - 1.2e-06 28.2 0.0 1.5e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EPE27406.1 - 1.8e-06 28.0 0.0 2.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPE27406.1 - 1.2e-05 25.2 1.8 0.024 14.6 0.3 2.3 1 1 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EPE27406.1 - 0.025 15.0 0.2 0.047 14.1 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EPE27406.1 - 0.065 13.5 0.0 3.9 7.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 EPE27406.1 - 0.081 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein GbpA_2 PF18416.1 EPE27406.1 - 0.086 13.1 1.5 8 6.8 1.5 2.3 1 1 0 1 1 1 0 N-acetylglucosamine binding protein domain 2 G-alpha PF00503.20 EPE27406.1 - 0.14 11.3 0.3 0.82 8.8 0.2 2.2 1 1 0 1 1 1 0 G-protein alpha subunit DUF2624 PF11116.8 EPE27406.1 - 0.29 12.0 1.3 2.5 9.1 1.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2624) Mitofilin PF09731.9 EPE27407.1 - 1.4e-161 539.5 27.2 5.2e-161 537.6 27.2 1.7 1 1 0 1 1 1 1 Mitochondrial inner membrane protein DUF4320 PF14208.6 EPE27407.1 - 0.26 11.4 4.2 0.6 10.2 4.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) Ribosomal_L20 PF00453.18 EPE27407.1 - 0.66 10.1 6.3 1.6 8.8 6.3 1.7 1 0 0 1 1 1 0 Ribosomal protein L20 V-ATPase_G_2 PF16999.5 EPE27407.1 - 8.3 6.9 21.8 1 9.8 16.7 2.2 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit PhyH PF05721.13 EPE27408.1 - 8e-10 39.3 0.1 2.4e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EPE27408.1 - 4.3e-06 25.7 0.0 0.016 14.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) Fungal_trans PF04082.18 EPE27409.1 - 2e-17 63.1 0.0 2.9e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF5538 PF17692.1 EPE27409.1 - 0.14 12.2 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5538) Sugar_tr PF00083.24 EPE27410.1 - 1.1e-98 331.0 22.6 1.3e-98 330.8 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE27410.1 - 2.3e-13 49.8 19.1 2.3e-13 49.8 19.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Man-6-P_recep PF02157.15 EPE27410.1 - 0.074 12.1 0.9 0.25 10.4 0.1 2.0 2 0 0 2 2 2 0 Mannose-6-phosphate receptor DUF3029 PF11230.8 EPE27413.1 - 0.019 13.4 0.1 0.024 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) MutS_V PF00488.21 EPE27414.1 - 2.5e-67 226.6 0.2 4.1e-67 225.9 0.2 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EPE27414.1 - 8.2e-41 140.3 0.0 1.5e-40 139.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EPE27414.1 - 1.1e-32 112.6 0.0 4.2e-32 110.7 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 EPE27414.1 - 2.5e-13 50.2 0.0 5.6e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EPE27414.1 - 4.4e-10 40.0 0.0 1.5e-09 38.2 0.0 1.9 1 1 0 1 1 1 1 MutS domain II AAA_23 PF13476.6 EPE27414.1 - 0.014 15.9 1.4 0.032 14.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EPE27414.1 - 0.043 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 EPE27414.1 - 0.049 13.4 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 EPE27414.1 - 0.18 11.4 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Shugoshin_C PF07557.11 EPE27414.1 - 6.8 6.6 8.8 0.3 10.9 1.0 2.4 2 0 0 2 2 2 0 Shugoshin C terminus Abhydrolase_2 PF02230.16 EPE27415.1 - 3.2e-19 69.6 0.2 3.8e-11 43.2 0.2 3.1 2 1 1 3 3 3 3 Phospholipase/Carboxylesterase FSH1 PF03959.13 EPE27415.1 - 4.7e-05 23.2 0.0 6.9e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 EPE27415.1 - 0.00036 20.1 0.0 0.00071 19.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Raffinose_syn PF05691.12 EPE27416.1 - 1.6e-53 181.6 3.0 1.9e-49 168.2 1.4 3.1 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 ocr PF08684.10 EPE27416.1 - 0.0011 19.4 0.1 0.0027 18.1 0.1 1.6 1 0 0 1 1 1 1 DNA mimic ocr Melibiase PF02065.18 EPE27416.1 - 0.0021 17.1 0.3 0.0035 16.3 0.3 1.3 1 0 0 1 1 1 1 Melibiase tRNA-synt_1b PF00579.25 EPE27417.1 - 2.5e-74 250.2 0.0 3.3e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EPE27417.1 - 1.4e-42 144.3 0.0 1.6e-41 140.9 0.0 2.2 2 0 0 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain CD34_antigen PF06365.12 EPE27418.1 - 0.03 13.9 0.1 0.041 13.5 0.1 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family Comm PF15957.5 EPE27418.1 - 0.071 13.5 0.1 0.1 13.0 0.1 1.3 1 0 0 1 1 1 0 Commissureless Peptidase_M28 PF04389.17 EPE27419.1 - 7.3e-33 113.9 0.0 1e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 DUF3328 PF11807.8 EPE27422.1 - 2.2e-55 187.8 0.0 2.6e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.8 EPE27424.1 - 5.2e-15 55.1 2.1 1.4e-13 50.5 1.5 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE27424.1 - 6.9e-05 22.9 8.7 0.00013 22.0 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_N PF00752.17 EPE27425.1 - 1.2e-34 118.8 0.0 3.2e-34 117.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EPE27425.1 - 2.9e-27 94.8 0.0 7.4e-27 93.5 0.0 1.8 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 EPE27425.1 - 0.00012 21.8 10.5 0.0025 17.6 1.8 3.8 3 0 0 3 3 3 2 Ubiquitin interaction motif XPG_I_2 PF12813.7 EPE27425.1 - 0.012 15.1 0.1 0.031 13.7 0.0 1.8 2 0 0 2 2 2 0 XPG domain containing 5_3_exonuc PF01367.20 EPE27425.1 - 0.025 15.2 0.0 0.16 12.6 0.0 2.5 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DSS1_SEM1 PF05160.13 EPE27425.1 - 0.14 12.3 11.5 1.2 9.2 0.9 3.8 3 0 0 3 3 3 0 DSS1/SEM1 family NAD_binding_10 PF13460.6 EPE27426.1 - 8.8e-10 38.8 0.0 2.9e-09 37.1 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPE27426.1 - 0.0019 17.8 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DUF1996 PF09362.10 EPE27427.1 - 2.2e-72 243.8 4.0 3.1e-72 243.4 4.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) adh_short PF00106.25 EPE27427.1 - 5.7e-36 123.8 0.1 9.1e-36 123.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE27427.1 - 1.2e-21 77.4 0.0 1.8e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EPE27427.1 - 0.056 12.8 0.0 0.62 9.4 0.0 2.0 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) EF-hand_1 PF00036.32 EPE27428.1 - 6.4e-11 41.0 3.9 0.00012 21.3 0.2 3.6 3 0 0 3 3 3 2 EF hand ZZ PF00569.17 EPE27428.1 - 1.6e-10 40.6 7.1 2.9e-10 39.8 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.6 EPE27428.1 - 1.4e-07 31.8 0.4 0.0067 16.9 0.2 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EPE27428.1 - 2.2e-06 27.1 2.4 0.0023 17.7 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EPE27428.1 - 0.00079 19.2 0.7 0.58 10.1 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair C1_2 PF03107.16 EPE27428.1 - 0.042 14.2 5.2 0.079 13.3 5.2 1.4 1 0 0 1 1 1 0 C1 domain Asp PF00026.23 EPE27429.1 - 9.2e-65 219.1 2.4 1.3e-64 218.7 2.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPE27429.1 - 9.4e-11 42.3 4.0 1.5e-08 35.1 1.9 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EPE27429.1 - 0.001 19.7 2.2 13 6.5 0.0 4.7 5 0 0 5 5 5 2 Aspartyl protease TAXi_C PF14541.6 EPE27429.1 - 0.0032 17.3 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EPE27429.1 - 0.054 14.1 0.5 38 4.9 0.0 4.2 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease SprA-related PF12118.8 EPE27429.1 - 2.1 7.4 6.7 4 6.5 6.7 1.4 1 0 0 1 1 1 0 SprA-related family Fungal_trans_2 PF11951.8 EPE27430.1 - 1e-07 31.2 0.0 0.011 14.6 0.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Atg31 PF09795.9 EPE27431.1 - 0.0043 17.1 0.0 0.0059 16.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 31 HAD_2 PF13419.6 EPE27433.1 - 2.1e-15 57.3 0.0 4.9e-15 56.1 0.0 1.7 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPE27433.1 - 7.1e-11 42.8 0.1 3.3e-09 37.3 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPE27433.1 - 6.4e-07 29.3 0.2 1.1e-06 28.6 0.2 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like MutS_IV PF05190.18 EPE27434.1 - 0.038 14.3 0.2 0.089 13.2 0.2 1.6 1 0 0 1 1 1 0 MutS family domain IV TelA PF05816.11 EPE27434.1 - 0.043 12.9 2.4 0.028 13.5 0.5 1.6 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) DUF2353 PF09789.9 EPE27434.1 - 0.05 13.0 6.0 0.016 14.6 2.4 1.8 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Fzo_mitofusin PF04799.13 EPE27434.1 - 0.079 12.5 1.4 0.15 11.6 1.4 1.5 1 0 0 1 1 1 0 fzo-like conserved region LegC3_N PF18654.1 EPE27434.1 - 0.14 11.3 5.5 0.23 10.7 5.5 1.2 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain HemX PF04375.14 EPE27434.1 - 0.19 11.0 3.7 0.3 10.3 3.7 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase IES5 PF17335.2 EPE27434.1 - 0.3 11.4 4.5 0.14 12.4 0.8 2.1 1 1 1 2 2 2 0 Ino80 complex subunit 5 KASH_CCD PF14662.6 EPE27434.1 - 0.95 9.3 6.7 0.083 12.7 1.5 1.9 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Myb_DNA-bind_4 PF13837.6 EPE27434.1 - 1.2 9.5 9.8 0.35 11.3 1.3 3.0 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Spc7_N PF15402.6 EPE27435.1 - 5.3e-272 905.3 78.8 1.2e-151 507.0 34.9 2.1 1 1 1 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 EPE27435.1 - 5.6e-120 399.9 2.4 5.6e-120 399.9 2.4 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 EPE27435.1 - 1.6e-20 72.9 2.2 3.4e-20 71.9 2.2 1.6 1 0 0 1 1 1 1 Spc7_C2 Ribosomal_S17_N PF16205.5 EPE27436.1 - 7.8e-33 112.7 0.2 1.3e-32 111.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EPE27436.1 - 6.3e-27 93.5 0.3 1.3e-26 92.5 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Glyco_hydro_61 PF03443.14 EPE27438.1 - 2.6e-60 203.9 0.1 4.4e-60 203.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EPE27438.1 - 2e-10 40.4 5.9 6.6e-10 38.8 5.9 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain p450 PF00067.22 EPE27439.1 - 1.1e-28 100.2 0.0 1.6e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.14 EPE27440.1 - 1.3e-101 339.8 0.1 2e-101 339.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EPE27440.1 - 1.2e-47 162.3 0.0 1.7e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32N PF00251.20 EPE27440.1 - 0.012 15.2 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain RskA PF10099.9 EPE27441.1 - 0.025 14.9 8.8 0.04 14.2 5.7 2.0 2 0 0 2 2 2 0 Anti-sigma-K factor rskA CYYR1 PF10873.8 EPE27441.1 - 0.041 14.3 1.8 0.048 14.1 0.2 1.9 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 LapA_dom PF06305.11 EPE27441.1 - 0.095 12.5 0.9 1.8 8.4 0.3 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Tetraspanin PF00335.20 EPE27441.1 - 1.7 8.3 7.2 1.2 8.8 0.2 2.5 3 0 0 3 3 3 0 Tetraspanin family HET PF06985.11 EPE27442.1 - 8.9e-21 74.8 0.0 1.6e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 EPE27443.1 - 1.5e-27 96.7 0.0 1e-26 94.1 0.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.29 EPE27444.1 - 9.3e-19 68.2 0.0 1.5e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE27444.1 - 8.9e-05 22.9 0.0 0.00038 20.9 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EPE27444.1 - 0.0047 16.7 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 EPE27444.1 - 0.0098 16.3 0.0 0.027 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EPE27444.1 - 0.01 16.1 0.2 0.052 13.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EPE27444.1 - 0.017 15.1 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EPE27444.1 - 0.072 13.2 0.0 0.96 9.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) Vps36_ESCRT-II PF11605.8 EPE27444.1 - 0.094 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Rad17 PF03215.15 EPE27444.1 - 0.11 12.4 0.3 0.38 10.7 0.0 2.0 3 0 0 3 3 3 0 Rad17 P-loop domain Zot PF05707.12 EPE27444.1 - 0.16 11.6 0.0 0.7 9.5 0.0 2.0 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) ATPase PF06745.13 EPE27444.1 - 0.19 11.0 0.1 0.45 9.8 0.1 1.5 1 0 0 1 1 1 0 KaiC ApbA_C PF08546.11 EPE27446.1 - 1.1e-29 103.2 0.1 7.1e-29 100.5 0.1 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EPE27446.1 - 1.4e-28 99.4 0.0 2e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Fungal_trans_2 PF11951.8 EPE27447.1 - 1.7e-39 135.8 0.7 2.1e-39 135.5 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE27447.1 - 5.6e-07 29.6 6.6 1.4e-06 28.3 6.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Isochorismatase PF00857.20 EPE27448.1 - 2.1e-16 60.6 0.0 3.7e-16 59.8 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family Mur_ligase_M PF08245.12 EPE27451.1 - 0.00025 21.1 0.0 0.00071 19.6 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain MFS_1 PF07690.16 EPE27452.1 - 8.5e-28 97.3 46.0 8.5e-28 97.3 46.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2157 PF09925.9 EPE27452.1 - 2.9 7.7 17.1 0.024 14.4 4.2 3.5 3 1 1 4 4 4 0 Predicted membrane protein (DUF2157) p450 PF00067.22 EPE27453.1 - 2.8e-37 128.6 0.0 3.7e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 EPE27454.1 - 9e-81 271.2 0.1 4.3e-80 268.9 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EPE27454.1 - 3e-36 124.0 0.1 8.7e-36 122.5 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 EPE27454.1 - 5.6e-22 77.4 0.1 1.9e-21 75.7 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain PS-DH PF14765.6 EPE27454.1 - 3.7e-20 72.4 0.0 5.9e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EPE27454.1 - 1.1e-16 61.4 0.0 2.8e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Acyl_transf_1 PF00698.21 EPE27454.1 - 2.1e-16 60.4 0.0 3.8e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.25 EPE27454.1 - 3.6e-14 52.9 0.3 2.2e-13 50.3 0.1 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_3 PF07859.13 EPE27454.1 - 5.7e-13 49.2 0.0 2.1e-11 44.1 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold SAT PF16073.5 EPE27454.1 - 3.9e-11 43.2 0.1 1.1e-06 28.6 0.0 3.5 2 1 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_23 PF13489.6 EPE27454.1 - 4.3e-11 42.9 0.0 5.1e-10 39.4 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE27454.1 - 4.1e-10 40.2 0.0 1.3e-09 38.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE27454.1 - 1.7e-07 31.8 0.0 5.1e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE27454.1 - 1.4e-06 28.2 0.0 3.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EPE27454.1 - 4e-06 27.3 0.0 1.1e-05 25.8 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Peptidase_S9 PF00326.21 EPE27454.1 - 8.5e-06 25.4 0.2 0.0025 17.3 0.0 2.4 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thiolase_N PF00108.23 EPE27454.1 - 3e-05 23.5 0.1 6e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 EPE27454.1 - 0.00016 21.5 0.0 0.0025 17.6 0.0 2.3 2 0 0 2 2 2 1 Lysine methyltransferase DLH PF01738.18 EPE27454.1 - 0.00016 21.3 0.0 0.22 11.0 0.0 2.9 3 0 0 3 3 2 2 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EPE27454.1 - 0.051 14.2 11.8 0.12 13.0 9.5 2.7 2 1 0 2 2 2 0 Alpha/beta hydrolase family RTP PF02334.16 EPE27454.1 - 0.071 13.8 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Replication terminator protein AXE1 PF05448.12 EPE27454.1 - 0.072 11.8 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF938 PF06080.12 EPE27454.1 - 0.099 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF938) ACP_syn_III PF08545.10 EPE27454.1 - 0.54 10.1 2.4 29 4.6 0.0 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III p450 PF00067.22 EPE27455.1 - 3.2e-56 191.0 0.0 3.9e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YtxC PF08812.11 EPE27455.1 - 0.061 12.9 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 YtxC-like family Methyltransf_25 PF13649.6 EPE27456.1 - 1.6e-08 35.2 0.0 3.3e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE27456.1 - 5e-07 30.3 0.0 8.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE27456.1 - 0.00094 19.9 0.0 0.0017 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE27456.1 - 0.0041 17.0 0.0 0.0059 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE27456.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GMC_oxred_N PF00732.19 EPE27458.1 - 2.2e-50 171.7 0.2 3.5e-50 171.1 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE27458.1 - 8.1e-33 114.0 0.7 1.4e-32 113.2 0.1 1.8 2 0 0 2 2 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EPE27458.1 - 9e-07 28.3 1.9 0.0029 16.8 0.9 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EPE27458.1 - 3e-05 23.2 0.7 0.00015 21.0 0.3 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPE27458.1 - 3.2e-05 24.1 0.3 0.00019 21.6 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EPE27458.1 - 0.00019 20.8 3.0 0.15 11.3 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE27458.1 - 0.0035 16.6 0.2 0.013 14.8 0.1 1.8 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EPE27458.1 - 0.0047 16.6 6.0 0.024 14.2 6.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE27458.1 - 0.0067 15.7 0.9 0.011 14.9 0.6 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE27458.1 - 0.031 13.0 0.1 0.051 12.3 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 EPE27458.1 - 0.082 11.7 1.4 0.13 11.1 1.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 EPE27458.1 - 0.085 13.1 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 EPE27458.1 - 0.11 12.5 0.4 0.24 11.4 0.4 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding PhyH PF05721.13 EPE27459.1 - 1.9e-13 51.1 0.0 3.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EPE27459.1 - 0.029 14.8 0.0 2.9 8.4 0.0 2.6 2 1 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase Trp_DMAT PF11991.8 EPE27460.1 - 4.4e-79 266.5 0.0 5.3e-79 266.3 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase DUF3328 PF11807.8 EPE27461.1 - 5.4e-21 75.4 0.3 8.1e-21 74.8 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.16 EPE27462.1 - 1.3e-22 80.2 19.6 1.2e-20 73.8 2.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EPE27463.1 - 1e-41 143.2 0.0 1.2e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 EPE27464.1 - 6.9e-09 35.6 0.0 9.2e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE27464.1 - 3.4e-07 30.3 0.0 4.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short_C2 PF13561.6 EPE27464.1 - 0.042 13.4 0.0 0.083 12.4 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE27464.1 - 0.091 12.7 0.1 26 4.7 0.0 2.9 2 1 0 3 3 3 0 KR domain Epimerase PF01370.21 EPE27464.1 - 0.12 11.8 0.0 0.41 10.1 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_2 PF00891.18 EPE27465.1 - 1.9e-24 86.2 0.0 2.7e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 EPE27465.1 - 0.021 14.9 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain p450 PF00067.22 EPE27466.1 - 6.8e-62 209.7 0.0 8.9e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2938 PF11158.8 EPE27467.1 - 0.0003 20.3 0.1 0.00032 20.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2938) dDENN PF03455.19 EPE27467.1 - 0.085 12.9 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 dDENN domain Myb_DNA-binding PF00249.31 EPE27468.1 - 3.8e-34 116.6 10.9 1.3e-14 54.1 0.4 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPE27468.1 - 2.6e-25 88.4 2.4 2.5e-11 43.7 0.2 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EPE27468.1 - 3e-05 23.8 0.0 0.15 12.0 0.0 2.5 2 0 0 2 2 2 2 Myb DNA-binding like MADF_DNA_bdg PF10545.9 EPE27468.1 - 1.4 9.3 4.2 8.3 6.8 0.2 3.0 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like p450 PF00067.22 EPE27469.1 - 2.2e-30 105.8 0.1 5.1e-17 61.8 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 3Beta_HSD PF01073.19 EPE27470.1 - 5e-57 193.0 0.0 8.3e-57 192.3 0.0 1.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPE27470.1 - 2.5e-26 92.6 0.1 3.2e-26 92.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE27470.1 - 3.8e-16 59.4 0.1 1.4e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EPE27470.1 - 4.2e-08 32.6 0.0 6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EPE27470.1 - 4.9e-06 25.9 0.1 0.00085 18.6 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EPE27470.1 - 6.1e-05 23.0 0.0 9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EPE27470.1 - 0.00018 20.8 0.1 0.00037 19.7 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EPE27470.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 EPE27470.1 - 0.0023 18.2 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 EPE27470.1 - 0.0057 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 KR domain ABC2_membrane PF01061.24 EPE27472.1 - 2.8e-28 98.8 22.4 2.8e-28 98.8 22.4 1.5 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 EPE27472.1 - 1.9e-25 88.6 0.0 1.9e-25 88.6 0.0 2.7 3 0 0 3 3 3 1 CDR ABC transporter ABC_tran PF00005.27 EPE27472.1 - 5.7e-16 59.3 0.3 1e-08 35.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.6 EPE27472.1 - 0.00036 20.2 0.1 0.00065 19.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EPE27472.1 - 0.015 15.0 0.4 0.034 13.9 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EPE27472.1 - 0.03 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 EPE27472.1 - 0.15 12.5 0.3 0.28 11.6 0.3 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 EPE27473.1 - 2.9e-33 115.0 28.0 2.9e-33 115.0 28.0 1.4 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 EPE27473.1 - 0.0011 18.9 2.6 0.023 14.6 0.1 3.0 2 0 0 2 2 2 1 CDR ABC transporter SMC_N PF02463.19 EPE27473.1 - 0.064 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain TFIID_NTD2 PF04494.15 EPE27473.1 - 0.14 12.4 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain ABC2_membrane_3 PF12698.7 EPE27473.1 - 0.15 11.2 31.6 0.039 13.1 26.6 2.4 1 1 1 2 2 2 0 ABC-2 family transporter protein IBR PF01485.21 EPE27474.1 - 1e-06 28.9 6.2 1e-06 28.9 6.2 3.8 3 2 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EPE27474.1 - 3.9e-05 23.9 5.2 3.9e-05 23.9 5.2 4.6 4 2 1 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPE27474.1 - 0.0024 17.7 5.4 0.0024 17.7 5.4 4.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE27474.1 - 0.0075 16.3 4.0 0.0075 16.3 4.0 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_5 PF17121.5 EPE27474.1 - 0.037 13.9 1.0 0.037 13.9 1.0 3.2 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF5635 PF18685.1 EPE27474.1 - 0.14 12.1 0.1 0.32 11.0 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5635) zf-ACC PF17848.1 EPE27474.1 - 0.52 10.4 9.6 0.16 12.0 1.1 3.4 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf-RING_7 PF02591.15 EPE27474.1 - 0.55 10.5 5.9 0.89 9.8 0.1 3.8 3 0 0 3 3 3 0 C4-type zinc ribbon domain Mur_ligase_M PF08245.12 EPE27475.1 - 8e-06 26.0 0.0 0.00023 21.2 0.0 2.7 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EPE27475.1 - 0.0016 18.6 0.0 0.0043 17.3 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 EPE27476.1 - 4.5e-05 23.5 0.0 0.16 12.0 0.0 3.1 3 0 0 3 3 3 2 Mur ligase middle domain Mur_ligase_C PF02875.21 EPE27476.1 - 0.043 14.1 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain CorA PF01544.18 EPE27477.1 - 2.1e-07 30.5 0.0 3.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein WD40 PF00400.32 EPE27479.1 - 1.3e-19 70.1 8.9 0.00074 20.3 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE27479.1 - 2.7e-15 56.4 0.0 3.3e-05 24.1 0.0 5.2 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE27479.1 - 1.5e-05 24.9 0.5 0.016 15.1 0.0 3.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EPE27479.1 - 0.0019 18.1 3.5 1.5 8.8 0.1 4.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat HIRA_B PF09453.10 EPE27479.1 - 0.0055 16.5 0.8 0.02 14.8 0.1 2.4 2 0 0 2 2 2 1 HIRA B motif WD40_like PF17005.5 EPE27479.1 - 0.11 11.7 0.0 0.79 9.0 0.0 2.3 3 0 0 3 3 3 0 WD40-like domain ABC_tran PF00005.27 EPE27480.1 - 1.5e-48 164.8 0.0 1.4e-28 100.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPE27480.1 - 8.1e-31 107.7 30.8 3.8e-22 79.2 9.5 3.8 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 EPE27480.1 - 2.4e-08 33.7 0.0 0.00014 21.4 0.0 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EPE27480.1 - 0.00017 22.0 2.0 0.35 11.3 0.0 3.7 4 0 0 4 4 4 2 AAA ATPase domain RsgA_GTPase PF03193.16 EPE27480.1 - 0.00057 19.8 0.0 0.51 10.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EPE27480.1 - 0.00097 19.2 0.1 0.11 12.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 EPE27480.1 - 0.0014 17.8 0.0 0.41 9.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 EPE27480.1 - 0.0016 18.7 0.9 1.6 9.0 0.0 3.2 3 1 0 3 3 3 2 AAA domain DUF87 PF01935.17 EPE27480.1 - 0.0017 18.5 0.1 1.2 9.2 0.1 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_29 PF13555.6 EPE27480.1 - 0.0025 17.5 0.1 4.4 7.1 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_25 PF13481.6 EPE27480.1 - 0.015 14.9 0.0 6.3 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EPE27480.1 - 0.017 14.4 0.0 0.3 10.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.23 EPE27480.1 - 0.034 14.2 0.1 9.3 6.3 0.0 2.8 3 0 0 3 3 3 0 Dynamin family IstB_IS21 PF01695.17 EPE27480.1 - 0.054 13.2 0.0 2.1 8.0 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_23 PF13476.6 EPE27480.1 - 0.14 12.6 0.4 11 6.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain CbiA PF01656.23 EPE27480.1 - 0.26 11.3 1.6 18 5.4 0.9 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Glyco_hydro_61 PF03443.14 EPE27481.1 - 2.1e-46 158.5 0.0 2.6e-46 158.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Vps52 PF04129.12 EPE27482.1 - 0.25 10.0 2.5 0.31 9.7 2.5 1.0 1 0 0 1 1 1 0 Vps52 / Sac2 family Glyco_hydro_79C PF16862.5 EPE27484.1 - 7.7e-26 91.0 0.5 2.2e-25 89.5 0.2 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Bac_A_amyl_C PF18612.1 EPE27484.1 - 0.14 11.9 0.5 7.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial Alpha amylase C-terminal domain p450 PF00067.22 EPE27485.1 - 1.7e-43 149.1 0.0 3.1e-43 148.2 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.22 EPE27486.1 - 1.2e-164 548.2 0.1 1.4e-164 548.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EPE27486.1 - 0.26 10.7 0.0 1.8 7.9 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) DUF676 PF05057.14 EPE27487.1 - 2.4e-05 23.9 0.0 4.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.12 EPE27487.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.13 EPE27487.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 PGAP1-like protein AAA_16 PF13191.6 EPE27487.1 - 0.02 15.3 0.0 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Abhydrolase_6 PF12697.7 EPE27487.1 - 0.061 13.9 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family ANAPC4_WD40 PF12894.7 EPE27488.1 - 4.9e-08 33.2 0.0 1.6 9.0 0.0 5.5 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EPE27488.1 - 7.3e-08 32.3 0.1 0.2 11.2 0.0 3.2 2 1 0 3 3 3 3 PQQ-like domain WD40 PF00400.32 EPE27488.1 - 0.001 19.8 4.8 6.5 7.8 0.1 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat PQQ PF01011.21 EPE27488.1 - 0.0044 16.9 0.0 2.6 8.1 0.0 3.7 3 0 0 3 3 3 1 PQQ enzyme repeat Peptidase_C50 PF03568.17 EPE27488.1 - 0.17 11.0 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C50 adh_short PF00106.25 EPE27489.1 - 1.2e-36 126.1 0.0 1.4e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE27489.1 - 1.1e-25 90.5 0.0 1.5e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE27489.1 - 4.6e-11 43.0 0.1 6.3e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE27489.1 - 8.2e-09 35.3 0.1 1.3e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPE27489.1 - 1.7e-05 24.8 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EPE27489.1 - 0.00025 20.6 0.1 0.00034 20.1 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EPE27489.1 - 0.00028 20.1 0.0 0.0004 19.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EPE27489.1 - 0.00066 19.3 0.1 0.0017 18.0 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 EPE27489.1 - 0.0024 17.0 0.0 0.0036 16.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EPE27489.1 - 0.15 11.2 0.2 1.2 8.2 0.2 2.0 1 1 0 1 1 1 0 Male sterility protein Fungal_trans PF04082.18 EPE27490.1 - 2.5e-16 59.5 0.2 2.5e-16 59.5 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE27490.1 - 3.1e-05 24.0 13.5 3.1e-05 24.0 13.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.6 EPE27492.1 - 6.1e-52 173.8 20.1 2.6e-11 43.6 0.1 9.6 7 2 4 11 11 10 8 Tetratricopeptide repeat TPR_10 PF13374.6 EPE27492.1 - 3.4e-45 150.7 10.8 1.7e-07 30.8 0.0 10.9 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_MalT PF17874.1 EPE27492.1 - 9.5e-15 54.8 7.9 4.7e-09 36.1 4.9 3.4 1 1 2 3 3 3 2 MalT-like TPR region NB-ARC PF00931.22 EPE27492.1 - 2e-12 46.8 0.1 4.8e-12 45.6 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain TPR_7 PF13176.6 EPE27492.1 - 4.5e-11 42.0 9.6 0.056 13.5 0.0 9.2 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_4 PF07721.14 EPE27492.1 - 4.9e-09 36.0 8.9 0.47 11.2 0.0 7.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EPE27492.1 - 6.8e-09 35.2 20.9 0.018 15.1 0.1 9.4 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_1 PF00515.28 EPE27492.1 - 1.9e-08 33.8 14.1 0.00034 20.3 0.0 8.6 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPE27492.1 - 1.9e-07 31.6 1.5 0.071 13.8 0.2 5.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPE27492.1 - 5.7e-07 29.2 10.3 2.7 8.4 0.1 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPE27492.1 - 8.9e-06 26.1 1.3 0.011 16.2 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPE27492.1 - 3e-05 24.5 5.3 44 5.3 0.0 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 EPE27492.1 - 0.0046 17.2 8.0 17 6.1 0.0 5.6 5 0 0 5 5 4 0 Tetratricopeptide repeat AAA_16 PF13191.6 EPE27492.1 - 0.0048 17.3 0.3 0.035 14.5 0.3 2.4 1 1 0 1 1 1 1 AAA ATPase domain ANAPC3 PF12895.7 EPE27492.1 - 0.023 14.9 7.0 0.66 10.2 0.1 4.5 6 0 0 6 6 4 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.6 EPE27492.1 - 0.03 14.6 0.0 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EPE27492.1 - 0.064 12.7 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein ATPase_2 PF01637.18 EPE27492.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Roc PF08477.13 EPE27492.1 - 0.13 12.5 0.0 0.43 10.8 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TPR_6 PF13174.6 EPE27492.1 - 1.2 9.9 12.4 1e+02 3.9 0.1 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat FAM131 PF15010.6 EPE27493.1 - 0.042 13.8 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative cell signalling Methyltransf_2 PF00891.18 EPE27494.1 - 2.2e-28 99.0 0.0 3.7e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain DUF2805 PF10985.8 EPE27494.1 - 0.031 14.6 0.0 0.062 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Peptidase_M48 PF01435.18 EPE27495.1 - 4.7e-09 36.3 0.0 0.0021 17.8 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M48 Peptidase_M78 PF06114.13 EPE27495.1 - 0.0014 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 IrrE N-terminal-like domain adh_short PF00106.25 EPE27496.1 - 7.7e-20 71.2 0.0 9.8e-19 67.6 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE27496.1 - 9.3e-12 45.0 0.0 2.6e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE27496.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 KR domain Fungal_trans_2 PF11951.8 EPE27497.1 - 2e-45 155.3 0.1 2.9e-45 154.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE27497.1 - 5.3e-07 29.7 12.7 1e-06 28.7 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NB-LRR PF12061.8 EPE27497.1 - 0.034 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Late blight resistance protein R1 Tyrosinase PF00264.20 EPE27498.1 - 4.4e-41 141.6 1.3 6.6e-41 141.0 1.3 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase CorA PF01544.18 EPE27499.1 - 0.0015 18.0 2.3 0.0044 16.4 2.3 1.8 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4100 PF13352.6 EPE27499.1 - 0.002 17.9 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4100) PAM2 PF07145.15 EPE27499.1 - 0.037 13.7 0.4 0.13 12.0 0.4 2.0 1 0 0 1 1 1 0 Ataxin-2 C-terminal region C6_DPF PF10170.9 EPE27500.1 - 0.24 11.8 6.2 0.57 10.6 6.2 1.7 1 1 0 1 1 1 0 Cysteine-rich domain FYVE_2 PF02318.16 EPE27500.1 - 0.56 10.4 5.7 0.13 12.4 2.6 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger FYVE PF01363.21 EPE27500.1 - 0.64 10.2 8.9 2.9 8.1 8.9 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_3 PF13920.6 EPE27500.1 - 2 8.3 9.9 0.38 10.6 5.9 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE27500.1 - 2 8.4 8.9 0.5 10.4 5.5 1.7 2 0 0 2 2 2 0 zinc-RING finger domain zf-B_box PF00643.24 EPE27500.1 - 8 6.7 9.9 0.46 10.7 1.4 2.6 3 0 0 3 3 3 0 B-box zinc finger zf-RanBP PF00641.18 EPE27500.1 - 9 5.7 11.7 0.12 11.7 1.1 2.9 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others HET PF06985.11 EPE27502.1 - 1.1e-34 119.9 0.0 1.8e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RbpA PF13397.6 EPE27502.1 - 0.14 12.8 0.0 0.26 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase-binding protein MFS_1 PF07690.16 EPE27503.1 - 4.3e-17 62.1 21.8 2.3e-16 59.7 21.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily COX7a PF02238.15 EPE27503.1 - 0.041 14.3 3.2 13 6.3 0.1 3.7 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII Methyltransf_2 PF00891.18 EPE27504.1 - 2.8e-24 85.6 0.0 4.7e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 EPE27504.1 - 0.0043 17.0 0.1 0.0095 15.9 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.6 EPE27504.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain NfrA_C PF13283.6 EPE27504.1 - 0.087 12.3 0.1 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 Bacteriophage N adsorption protein A C-term DNA_pol_A_exo1 PF01612.20 EPE27505.1 - 0.0003 20.6 0.0 0.0006 19.6 0.0 1.4 1 1 0 1 1 1 1 3'-5' exonuclease zf-C5HC2 PF02928.16 EPE27506.1 - 3.1 8.3 9.1 1.9 8.9 3.9 2.4 2 1 0 2 2 2 0 C5HC2 zinc finger HATPase_c PF02518.26 EPE27507.1 - 1.5e-21 77.0 0.2 6.1e-21 75.0 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPE27507.1 - 6.3e-21 74.6 0.1 1.4e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPE27507.1 - 4.5e-09 36.2 0.0 1e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 EPE27507.1 - 0.00033 20.9 0.0 0.0014 18.9 0.0 2.2 1 0 0 1 1 1 1 PAS fold GAF_3 PF13492.6 EPE27507.1 - 0.00052 20.4 0.0 0.0018 18.6 0.0 2.0 1 0 0 1 1 1 1 GAF domain PAS PF00989.25 EPE27507.1 - 0.0041 17.1 0.0 0.019 14.9 0.0 2.2 2 1 0 2 2 2 1 PAS fold PAS_8 PF13188.7 EPE27507.1 - 0.017 15.1 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 0 PAS domain GAF_2 PF13185.6 EPE27507.1 - 0.06 13.6 0.0 0.21 11.9 0.0 2.0 1 0 0 1 1 1 0 GAF domain FAD_binding_3 PF01494.19 EPE27508.1 - 1.9e-17 63.6 0.0 3.4e-17 62.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE27508.1 - 3.9e-06 26.3 0.0 1.9e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE27508.1 - 0.00011 22.4 0.1 0.00027 21.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EPE27508.1 - 0.00018 22.0 0.0 0.0042 17.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE27508.1 - 0.0002 20.2 0.0 0.00032 19.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.10 EPE27508.1 - 0.00022 20.4 0.0 0.00046 19.3 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 EPE27508.1 - 0.00055 19.6 0.0 0.011 15.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EPE27508.1 - 0.0016 17.7 0.0 0.0034 16.7 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EPE27508.1 - 0.0026 16.9 0.1 0.0043 16.2 0.1 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EPE27508.1 - 0.011 15.1 0.2 0.047 13.0 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EPE27508.1 - 0.051 13.4 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EPE27508.1 - 0.056 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Peptidase_M24 PF00557.24 EPE27509.1 - 1.9e-41 142.1 0.1 2.4e-41 141.7 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EPE27509.1 - 9.1e-20 70.7 7.7 9.1e-20 70.7 7.7 1.8 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EPE27509.1 - 0.0015 18.6 5.1 0.0015 18.6 5.1 2.2 2 0 0 2 2 2 1 MYND finger Cornichon PF03311.14 EPE27510.1 - 4.8e-44 149.6 12.1 1.1e-37 129.0 5.4 2.1 2 0 0 2 2 2 2 Cornichon protein WD40 PF00400.32 EPE27511.1 - 4.4e-30 103.3 10.4 3e-07 31.0 0.3 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE27511.1 - 3.9e-13 49.5 0.2 1.7e-05 25.0 0.1 4.5 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE27511.1 - 0.00015 21.7 1.3 0.18 11.6 0.1 3.0 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EPE27511.1 - 0.032 12.9 1.6 0.19 10.3 0.1 2.6 1 1 2 3 3 3 0 Nucleoporin Nup120/160 ADPRTs_Tse2 PF18648.1 EPE27511.1 - 0.052 13.6 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Tse2 ADP-ribosyltransferase toxins DUF1513 PF07433.11 EPE27511.1 - 0.076 12.1 0.2 0.27 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) MFS_1 PF07690.16 EPE27512.1 - 2.4e-09 36.6 12.2 3.2e-09 36.2 12.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE27512.1 - 0.03 13.2 4.6 0.034 13.0 4.6 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter MFS_1_like PF12832.7 EPE27512.1 - 0.054 12.3 6.7 0.066 12.1 6.7 1.1 1 0 0 1 1 1 0 MFS_1 like family Myc_N PF01056.18 EPE27514.1 - 0.002 18.1 0.2 0.0039 17.2 0.2 1.4 1 0 0 1 1 1 1 Myc amino-terminal region ATG7_N PF16420.5 EPE27515.1 - 0.0035 17.0 0.1 2.3 7.8 0.0 2.3 1 1 1 2 2 2 2 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Kdo PF06293.14 EPE27516.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_7 PF00840.20 EPE27520.1 - 3.6e-153 510.4 2.8 4e-153 510.2 2.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Vps16_N PF04841.13 EPE27520.1 - 0.25 10.0 0.0 0.73 8.5 0.0 1.6 2 0 0 2 2 2 0 Vps16, N-terminal region SMC_ScpA PF02616.14 EPE27521.1 - 0.16 11.9 1.6 0.18 11.7 1.6 1.1 1 0 0 1 1 1 0 Segregation and condensation protein ScpA GrpE PF01025.19 EPE27521.1 - 0.45 10.2 7.9 0.86 9.2 7.9 1.4 1 0 0 1 1 1 0 GrpE Pescadillo_N PF06732.11 EPE27525.1 - 1.5e-120 401.8 3.7 2e-120 401.5 0.0 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.26 EPE27525.1 - 2.5e-06 27.8 0.0 7.7e-05 23.0 0.0 2.7 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EPE27525.1 - 0.0018 18.7 0.2 0.0081 16.6 0.2 2.1 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain MMM1 PF10296.9 EPE27525.1 - 0.28 10.2 2.7 0.57 9.2 2.7 1.4 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 PIG-U PF06728.13 EPE27526.1 - 3.4e-124 414.8 28.9 3.8e-124 414.6 28.9 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U PIRT PF15099.6 EPE27526.1 - 0.014 15.0 0.1 0.038 13.6 0.1 1.8 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family 8TM_micro PF17028.5 EPE27526.1 - 0.6 9.8 15.5 0.025 14.3 9.6 1.6 2 0 0 2 2 2 0 8TM Microsporidial transmembrane domain RRN9 PF10680.9 EPE27527.1 - 6.8e-22 77.5 0.1 3.7e-21 75.2 0.1 2.4 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2 PF00096.26 EPE27527.1 - 0.00073 19.9 1.0 0.00073 19.9 1.0 1.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE27527.1 - 0.005 17.6 0.6 0.005 17.6 0.6 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger RRN3 PF05327.11 EPE27527.1 - 0.22 10.0 4.5 0.3 9.6 4.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 EPE27527.1 - 8.1 4.4 10.9 11 3.9 10.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Abhydrolase_6 PF12697.7 EPE27529.1 - 2.8e-10 41.2 0.3 3.8e-10 40.7 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE27529.1 - 1.5e-08 34.6 0.1 2.1e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE27529.1 - 1.6e-08 34.2 0.0 2.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EPE27529.1 - 2.5e-05 23.9 0.0 5.6e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EPE27529.1 - 4e-05 23.6 0.0 5.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.22 EPE27529.1 - 0.039 13.9 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF818 PF05677.12 EPE27529.1 - 0.09 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 EPE27529.1 - 0.096 12.5 0.1 0.27 11.0 0.1 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 EPE27529.1 - 0.2 10.3 0.3 0.4 9.3 0.3 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) NMT_C PF02799.15 EPE27530.1 - 2.6e-89 298.3 0.0 5.1e-89 297.3 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EPE27530.1 - 4.4e-74 247.6 0.7 2.4e-72 242.0 0.1 2.2 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EPE27530.1 - 0.00017 21.6 0.1 0.0024 17.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE27530.1 - 0.018 15.2 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NTP_transf_9 PF04248.12 EPE27530.1 - 0.04 13.8 0.1 0.09 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) FAM60A PF15396.6 EPE27530.1 - 0.57 10.2 4.3 0.97 9.4 4.3 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Dicty_REP PF05086.12 EPE27530.1 - 1.4 6.8 5.7 2.1 6.2 5.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PGA2 PF07543.12 EPE27530.1 - 2.8 7.9 12.8 4.6 7.2 12.8 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Ndc1_Nup PF09531.10 EPE27530.1 - 7.6 5.1 7.4 12 4.5 7.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4407 PF14362.6 EPE27530.1 - 8.7 5.6 12.6 14 5.0 12.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Abhydrolase_1 PF00561.20 EPE27531.1 - 3.5e-13 49.8 0.0 3.3e-12 46.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE27531.1 - 7.2e-12 46.4 1.7 3.4e-11 44.2 0.1 2.5 3 0 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE27531.1 - 4.7e-10 39.1 0.0 8e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF2048 PF09752.9 EPE27531.1 - 0.0028 16.8 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Thioesterase PF00975.20 EPE27531.1 - 0.021 14.9 0.3 0.049 13.7 0.0 1.7 2 0 0 2 2 2 0 Thioesterase domain Esterase PF00756.20 EPE27531.1 - 0.026 14.2 0.0 0.052 13.2 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Dynamin_N PF00350.23 EPE27532.1 - 1.7e-28 99.8 4.0 1.9e-28 99.7 0.1 2.5 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 EPE27532.1 - 9.9e-26 90.6 2.1 9.3e-22 77.6 0.3 2.6 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EPE27532.1 - 2.9e-06 27.3 0.0 0.052 13.6 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EPE27532.1 - 0.007 16.2 2.0 0.018 14.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system GCIP PF13324.6 EPE27532.1 - 0.025 14.2 2.1 0.046 13.3 2.1 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting ABC_tran PF00005.27 EPE27532.1 - 0.064 13.8 0.0 0.39 11.2 0.0 2.4 2 1 0 2 2 2 0 ABC transporter DUF913 PF06025.12 EPE27532.1 - 0.065 12.2 1.8 0.15 11.0 1.8 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pes-10 PF07149.11 EPE27532.1 - 0.075 12.1 6.4 0.13 11.3 6.4 1.3 1 0 0 1 1 1 0 Pes-10 NOA36 PF06524.12 EPE27532.1 - 0.081 12.2 7.3 0.13 11.5 7.3 1.3 1 0 0 1 1 1 0 NOA36 protein AAA_29 PF13555.6 EPE27532.1 - 0.17 11.7 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF719 PF05334.13 EPE27532.1 - 0.26 11.5 3.0 0.79 9.9 3.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF719) RXT2_N PF08595.11 EPE27532.1 - 0.27 11.2 6.3 0.71 9.9 6.3 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4407 PF14362.6 EPE27532.1 - 0.32 10.3 4.4 0.18 11.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AAA_23 PF13476.6 EPE27532.1 - 0.58 10.6 0.0 0.58 10.6 0.0 3.4 2 1 0 2 2 1 0 AAA domain AAA_15 PF13175.6 EPE27532.1 - 1.1 8.9 15.3 8.6e+02 -0.6 15.0 2.9 1 1 0 1 1 1 0 AAA ATPase domain DUF4637 PF15470.6 EPE27532.1 - 3.2 7.5 10.9 5.5 6.7 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CobT PF06213.12 EPE27532.1 - 3.2 7.1 12.8 7.4 5.9 12.8 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 EPE27532.1 - 3.8 6.8 14.3 6.5 6.1 14.3 1.2 1 0 0 1 1 1 0 SDA1 DUF3740 PF12548.8 EPE27532.1 - 4.4 7.7 9.0 0.64 10.5 0.6 2.8 3 0 0 3 3 2 0 Sulfatase protein Sporozoite_P67 PF05642.11 EPE27532.1 - 5.8 4.9 7.5 9.1 4.2 7.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hormone_4 PF00220.17 EPE27533.1 - 0.54 10.4 4.4 9.3 6.5 0.1 3.3 3 0 0 3 3 3 0 Neurohypophysial hormones, N-terminal Domain PAP_central PF04928.17 EPE27534.1 - 0.019 14.0 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain Amidinotransf PF02274.17 EPE27534.1 - 0.079 12.0 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Amidinotransferase ABM PF03992.16 EPE27535.1 - 9.8e-06 25.6 1.1 0.00028 20.9 0.0 2.4 3 0 0 3 3 3 2 Antibiotic biosynthesis monooxygenase KxDL PF10241.9 EPE27537.1 - 0.22 11.8 6.5 0.35 11.2 0.9 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein TEBP_beta PF07404.11 EPE27537.1 - 0.77 9.0 8.9 2 7.7 8.9 1.7 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) DUF92 PF01940.16 EPE27538.1 - 2.6e-88 295.4 0.7 3.2e-88 295.1 0.7 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Amidase PF01425.21 EPE27539.1 - 5.5e-69 233.3 0.1 2e-63 215.0 0.0 2.1 2 0 0 2 2 2 2 Amidase p450 PF00067.22 EPE27540.1 - 7.9e-66 222.7 0.0 1.4e-56 192.2 0.0 2.6 3 0 0 3 3 3 2 Cytochrome P450 Flavodoxin_1 PF00258.25 EPE27540.1 - 2.3e-19 70.0 0.0 4.3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 EPE27540.1 - 5.5e-17 62.1 0.1 9.4e-17 61.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EPE27540.1 - 4.4e-13 49.8 0.0 1.2e-12 48.4 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EPE27540.1 - 0.13 12.4 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Tyrosinase PF00264.20 EPE27541.1 - 2.1e-45 155.7 4.0 3.6e-45 155.0 4.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EPE27541.1 - 0.065 13.9 0.4 0.23 12.1 0.1 2.1 2 1 0 2 2 2 0 Tyosinase C-terminal domain Glyco_hydro_114 PF03537.13 EPE27542.1 - 8.5e-73 244.5 0.1 9.8e-73 244.3 0.1 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 FMN_dh PF01070.18 EPE27542.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DAO PF01266.24 EPE27543.1 - 2.8e-47 162.0 0.0 3.3e-47 161.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE27543.1 - 7.6e-05 22.9 0.0 0.00021 21.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EPE27543.1 - 0.0046 16.3 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EPE27543.1 - 0.0053 15.9 0.0 0.014 14.5 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EPE27543.1 - 0.015 14.6 0.0 0.079 12.2 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE27543.1 - 0.022 13.5 0.1 0.82 8.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.14 EPE27543.1 - 0.027 13.7 0.1 0.043 13.0 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE27543.1 - 0.086 12.1 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Mqo PF06039.15 EPE27543.1 - 0.097 11.2 0.1 0.94 7.9 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) DUF4404 PF14357.6 EPE27543.1 - 0.23 12.1 0.2 0.48 11.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) UCR_6-4kD PF08997.10 EPE27544.1 - 0.13 12.2 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Ifi-6-16 PF06140.13 EPE27545.1 - 1.9e-08 34.1 26.9 1.9e-08 34.1 26.9 1.9 1 1 1 2 2 2 1 Interferon-induced 6-16 family Myc_target_1 PF15179.6 EPE27547.1 - 0.013 15.4 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Myc target protein 1 TMEM52 PF14979.6 EPE27547.1 - 0.12 12.3 1.8 0.16 11.9 1.7 1.3 1 1 0 1 1 1 0 Transmembrane 52 Dynamitin PF04912.14 EPE27548.1 - 0.024 14.0 1.7 0.054 12.8 1.7 1.5 1 0 0 1 1 1 0 Dynamitin XhlA PF10779.9 EPE27548.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.3 3 0 0 3 3 3 0 Haemolysin XhlA MucB_RseB PF03888.14 EPE27549.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 MucB/RseB N-terminal domain Ifi-6-16 PF06140.13 EPE27550.1 - 1.8e-09 37.3 25.2 3.2e-09 36.6 25.2 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family Ifi-6-16 PF06140.13 EPE27551.1 - 1.8e-07 31.0 22.3 3e-07 30.3 22.3 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family AMPK1_CBM PF16561.5 EPE27551.1 - 0.097 12.9 0.0 0.66 10.2 0.0 2.1 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase APH PF01636.23 EPE27555.1 - 7.4e-11 42.4 0.1 1.6e-09 38.1 0.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE27555.1 - 0.078 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 EPE27555.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Methyltransf_11 PF08241.12 EPE27556.1 - 1.9e-20 73.3 0.0 3.1e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE27556.1 - 9.1e-17 61.2 0.0 1.2e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE27556.1 - 1.9e-16 60.5 0.0 3.1e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE27556.1 - 6.4e-12 45.6 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Sterol_MT_C PF08498.10 EPE27556.1 - 1.7e-09 37.9 0.1 2.8e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_12 PF08242.12 EPE27556.1 - 8.7e-09 36.0 0.0 2.5e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EPE27556.1 - 7.9e-08 31.9 0.0 1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EPE27556.1 - 2.5e-07 30.3 0.0 3.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 EPE27556.1 - 0.0051 16.7 0.0 0.0072 16.2 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 EPE27556.1 - 0.064 11.8 0.0 0.081 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CHAT PF12770.7 EPE27557.1 - 3.5e-26 92.3 0.0 8.4e-26 91.0 0.0 1.6 2 0 0 2 2 2 1 CHAT domain Peptidase_C50 PF03568.17 EPE27557.1 - 5.7e-06 25.7 1.0 1.3e-05 24.5 0.0 2.1 3 0 0 3 3 3 1 Peptidase family C50 DinB PF05163.12 EPE27557.1 - 0.00029 20.8 0.0 0.00079 19.4 0.0 1.7 1 0 0 1 1 1 1 DinB family EF-G-binding_N PF07299.11 EPE27557.1 - 0.23 12.0 1.7 18 5.9 0.0 2.7 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal SIS PF01380.22 EPE27559.1 - 6.2e-13 48.7 0.1 2.7e-12 46.7 0.1 2.1 1 1 0 1 1 1 1 SIS domain IMS_HHH PF11798.8 EPE27559.1 - 0.021 15.2 0.4 14 6.2 0.1 3.3 3 0 0 3 3 3 0 IMS family HHH motif SIS_2 PF13580.6 EPE27559.1 - 0.047 13.7 0.0 3.1 7.8 0.0 2.4 1 1 1 2 2 2 0 SIS domain WW PF00397.26 EPE27560.1 - 0.053 13.6 0.1 0.15 12.2 0.1 1.9 1 0 0 1 1 1 0 WW domain CDC45 PF02724.14 EPE27560.1 - 3.1 6.0 7.2 3.8 5.7 7.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 EPE27561.1 - 3.4e-21 75.8 0.0 5.1e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE27561.1 - 4.6e-14 52.3 0.0 8.5e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EPE27562.1 - 4.1e-19 69.0 0.0 6.9e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE27562.1 - 1.6e-12 47.2 0.0 2.7e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HET PF06985.11 EPE27563.1 - 1.6e-18 67.5 0.2 3.2e-18 66.5 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cyt-b5 PF00173.28 EPE27564.1 - 1.9e-20 72.8 0.5 2.1e-20 72.6 0.5 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 EPE27564.1 - 0.048 13.8 0.0 0.081 13.0 0.0 1.4 1 1 0 1 1 1 0 V-ATPase subunit H CAF-1_p150 PF11600.8 EPE27567.1 - 0.048 13.4 7.8 0.063 13.0 7.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TMF_TATA_bd PF12325.8 EPE27568.1 - 0.026 14.7 0.4 0.042 14.1 0.4 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding zf-C2H2_4 PF13894.6 EPE27569.1 - 2.3e-06 28.0 11.4 0.045 14.6 0.3 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EPE27569.1 - 0.052 14.0 21.0 0.32 11.5 0.2 4.4 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C4pol PF14260.6 EPE27569.1 - 0.21 12.1 0.9 28 5.3 0.2 2.6 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-C2H2_jaz PF12171.8 EPE27569.1 - 0.52 10.7 8.1 5.6 7.4 0.4 3.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EPE27570.1 - 1.3e-07 31.7 40.6 0.002 18.5 0.2 7.3 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EPE27570.1 - 0.0009 19.5 23.2 0.18 12.2 2.0 5.8 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EPE27570.1 - 0.013 16.3 56.4 0.066 14.1 0.2 8.1 9 0 0 9 9 9 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EPE27570.1 - 0.069 13.3 0.2 0.069 13.3 0.2 2.4 2 1 1 3 3 3 0 Aberrant zinc-finger FOXP-CC PF16159.5 EPE27570.1 - 0.56 10.9 17.3 2.4 8.9 0.1 4.9 4 1 1 5 5 5 0 FOXP coiled-coil domain Cyt-b5 PF00173.28 EPE27571.1 - 1.3e-08 34.9 0.0 1.5e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPR_12 PF13424.6 EPE27572.1 - 7.5e-08 32.6 6.1 0.12 12.7 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPE27572.1 - 0.015 15.4 14.1 0.37 11.0 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Enkurin PF13864.6 EPE27572.1 - 0.021 15.3 0.2 0.057 13.9 0.2 1.7 1 0 0 1 1 1 0 Calmodulin-binding TPR_7 PF13176.6 EPE27572.1 - 0.074 13.1 1.2 54 4.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2482 PF10655.9 EPE27572.1 - 0.093 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2482) TPR_1 PF00515.28 EPE27572.1 - 0.1 12.4 3.8 31 4.6 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPE27572.1 - 1.1 9.2 12.6 24 5.0 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPE27572.1 - 7 7.8 7.0 1.4e+02 3.7 0.0 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat F-protein PF00469.20 EPE27574.1 - 0.11 12.1 0.3 0.18 11.3 0.0 1.5 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef LysM PF01476.20 EPE27577.1 - 8.2e-19 67.4 0.0 0.00011 22.1 0.0 6.2 6 0 0 6 6 6 6 LysM domain Hydrophob_seed PF14547.6 EPE27577.1 - 0.88 9.8 5.4 3.4 7.9 1.6 2.6 2 0 0 2 2 2 0 Hydrophobic seed protein LysM PF01476.20 EPE27579.1 - 1.3e-09 38.0 0.0 2.7e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 LysM domain Glyco_hydro_18 PF00704.28 EPE27580.1 - 1.7e-63 215.2 0.0 2.9e-63 214.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EPE27580.1 - 5.1e-08 33.3 17.0 5.1e-08 33.3 17.0 3.7 3 0 0 3 3 3 1 Chitin recognition protein DNase_NucA_NucB PF14040.6 EPE27580.1 - 6.4e-06 26.5 0.0 0.00013 22.3 0.1 2.7 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB Ceramidase PF05875.12 EPE27582.1 - 6.3e-94 314.3 9.9 7.8e-94 314.0 9.9 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.11 EPE27582.1 - 0.11 12.5 1.5 0.36 10.9 1.5 1.9 1 0 0 1 1 1 0 Trp-operon Leader Peptide ADH_N PF08240.12 EPE27583.1 - 3.6e-18 65.5 0.4 6.4e-18 64.6 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE27583.1 - 1.2e-15 57.6 0.5 2e-15 56.9 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE27583.1 - 3.9e-06 28.0 0.0 2.3e-05 25.5 0.0 2.0 1 1 1 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 EPE27583.1 - 0.098 12.5 0.4 0.15 11.9 0.4 1.3 1 0 0 1 1 1 0 NAD(P)H-binding DUF3970 PF13113.6 EPE27584.1 - 0.087 13.1 1.1 0.14 12.4 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) Peptidase_M48 PF01435.18 EPE27585.1 - 7e-37 127.1 0.0 9.5e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Kelch_3 PF13415.6 EPE27586.1 - 1.9e-22 79.0 15.6 7.9e-07 29.2 0.1 6.6 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EPE27586.1 - 3.3e-17 62.1 0.8 0.00036 20.4 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 EPE27586.1 - 3.6e-17 62.1 14.0 0.0002 21.3 0.5 7.0 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EPE27586.1 - 6.3e-17 61.2 2.1 1.9e-07 31.1 0.0 4.9 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EPE27586.1 - 4.9e-15 54.8 3.0 1.7e-08 33.9 0.1 5.0 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EPE27586.1 - 3.3e-13 49.0 6.6 2.5e-06 27.2 0.1 5.7 5 1 1 6 6 6 3 Kelch motif dCMP_cyt_deam_1 PF00383.23 EPE27587.1 - 2.4e-10 40.2 0.2 3.2e-10 39.8 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EPE27587.1 - 2.5e-06 27.3 0.1 3.1e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EPE27587.1 - 0.015 15.5 1.3 0.025 14.7 1.3 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 EPE27587.1 - 0.12 12.4 0.2 0.24 11.5 0.2 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase Transferase PF02458.15 EPE27588.1 - 1.4e-36 126.1 0.0 5.2e-36 124.2 0.0 1.9 1 1 0 1 1 1 1 Transferase family ApbA PF02558.16 EPE27589.1 - 2.9e-29 101.7 0.0 4.8e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EPE27589.1 - 1.7e-24 86.4 0.0 2.9e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal 2Fe-2S_thioredx PF01257.19 EPE27590.1 - 1.4e-60 203.3 0.1 1.8e-60 203.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin LRR_6 PF13516.6 EPE27591.1 - 1.4e-11 43.4 2.5 0.0072 16.3 0.0 7.2 8 0 0 8 8 8 2 Leucine Rich repeat F-box-like PF12937.7 EPE27591.1 - 4.1e-09 36.2 0.0 1.5e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EPE27591.1 - 1.4e-08 34.9 3.4 0.013 15.9 0.3 5.1 4 3 0 5 5 5 2 Leucine Rich repeats (2 copies) F-box PF00646.33 EPE27591.1 - 7.3e-06 25.7 0.0 2.7e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 EPE27591.1 - 0.15 12.7 9.2 1.1 10.0 0.1 5.6 8 0 0 8 8 8 0 Leucine Rich Repeat HET PF06985.11 EPE27592.1 - 1.8e-32 112.7 0.0 3.2e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LIDHydrolase PF10230.9 EPE27594.1 - 1.4e-59 201.9 0.0 1.6e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 EPE27594.1 - 8e-05 23.3 0.0 0.0001 23.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 EPE27594.1 - 0.005 16.4 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 EPE27594.1 - 0.015 14.5 0.0 0.031 13.5 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EPE27594.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EPE27594.1 - 0.035 14.2 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 EPE27594.1 - 0.056 13.1 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EPE27594.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase SNF2_N PF00176.23 EPE27595.1 - 7.3e-72 242.0 0.7 7.3e-72 242.0 0.7 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE27595.1 - 5.9e-20 71.7 1.8 1.3e-18 67.4 0.0 3.6 3 1 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 EPE27595.1 - 1.3e-18 66.8 0.1 3.3e-18 65.5 0.1 1.7 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 EPE27595.1 - 3.5e-18 65.7 15.4 3.5e-18 65.7 15.4 4.5 5 1 0 5 5 5 1 HSA QLQ PF08880.11 EPE27595.1 - 6.4e-14 51.4 2.1 6.4e-14 51.4 2.1 3.0 3 0 0 3 3 3 1 QLQ SnAC PF14619.6 EPE27595.1 - 1.8e-13 50.8 0.1 1.8e-13 50.8 0.1 4.5 5 0 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 EPE27595.1 - 4.3e-09 36.6 0.0 4.3e-09 36.6 0.0 3.8 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Mucin PF01456.17 EPE27595.1 - 1.7 8.6 10.5 4.1 7.4 10.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Form_Nir_trans PF01226.17 EPE27596.1 - 1.2e-70 237.5 20.0 1.4e-70 237.3 20.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter SpecificRecomb PF10136.9 EPE27596.1 - 0.007 14.7 1.5 0.007 14.7 1.5 1.3 1 1 0 1 1 1 1 Site-specific recombinase Peptidase_M18 PF02127.15 EPE27597.1 - 3.2e-165 550.1 0.0 4.6e-165 549.6 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) PBD PF00786.28 EPE27598.1 - 0.031 14.6 1.4 0.091 13.1 1.4 1.8 1 0 0 1 1 1 0 P21-Rho-binding domain TPR_2 PF07719.17 EPE27601.1 - 2.1e-23 80.5 34.4 0.0033 17.4 0.0 13.1 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_1 PF00515.28 EPE27601.1 - 1.8e-20 71.8 30.6 0.00016 21.3 0.0 11.7 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_8 PF13181.6 EPE27601.1 - 1.3e-15 56.2 25.3 0.2 11.9 0.1 11.9 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_12 PF13424.6 EPE27601.1 - 4e-15 55.9 26.4 0.0036 17.6 0.7 11.0 8 3 2 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 EPE27601.1 - 1.9e-14 53.9 26.4 0.0043 17.5 0.0 9.7 7 3 2 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 EPE27601.1 - 6.8e-14 51.3 16.9 0.076 12.7 0.0 9.6 8 1 2 10 10 10 5 TPR repeat TPR_17 PF13431.6 EPE27601.1 - 3.7e-11 42.6 11.8 0.14 12.6 0.1 11.2 13 0 0 13 13 11 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPE27601.1 - 5.6e-10 39.2 38.1 0.11 13.4 0.1 11.3 12 3 2 14 14 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 EPE27601.1 - 6.8e-09 35.1 21.8 0.012 15.6 0.0 9.8 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_6 PF13174.6 EPE27601.1 - 1.9e-06 28.1 26.2 0.71 10.6 0.0 11.8 13 0 0 13 13 11 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPE27601.1 - 4.1e-05 24.1 3.2 0.019 15.6 0.4 9.2 11 0 0 11 11 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 EPE27601.1 - 0.0015 18.3 23.9 0.41 10.6 0.1 7.7 11 0 0 11 11 10 4 Tetratricopeptide repeat HTH_Bact PF18768.1 EPE27601.1 - 0.32 10.6 4.1 7.1 6.3 0.0 4.1 4 0 0 4 4 3 0 Helix-turn-helix bacterial domain Fis1_TPR_C PF14853.6 EPE27601.1 - 0.62 10.2 6.3 6.2 7.0 0.1 5.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 EPE27601.1 - 0.65 10.3 11.6 0.37 11.0 0.1 5.7 8 1 0 8 8 7 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF2834 PF11196.8 EPE27602.1 - 3e-07 30.7 1.0 0.00059 20.1 0.8 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF2834) Arf PF00025.21 EPE27603.1 - 1e-39 135.8 0.0 1.6e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EPE27603.1 - 1.8e-14 53.7 0.0 2e-09 37.1 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EPE27603.1 - 1.9e-09 37.8 0.0 3.5e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EPE27603.1 - 2e-08 33.9 0.0 2.5e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EPE27603.1 - 1e-07 31.7 0.0 1.8e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Ras family SRPRB PF09439.10 EPE27603.1 - 2.6e-06 27.0 0.0 4.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EPE27603.1 - 0.00014 21.9 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EPE27603.1 - 0.00067 19.3 0.1 0.0091 15.6 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EPE27603.1 - 0.16 11.7 0.0 0.39 10.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain Pro_CA PF00484.19 EPE27604.1 - 3.6e-06 27.4 0.0 5.3e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Carbonic anhydrase SepF PF04472.12 EPE27604.1 - 0.078 13.3 0.0 0.21 11.9 0.0 1.7 2 0 0 2 2 2 0 Cell division protein SepF GBP_repeat PF02526.14 EPE27604.1 - 0.12 12.1 0.5 0.38 10.5 0.2 1.9 2 0 0 2 2 2 0 Glycophorin-binding protein GMC_oxred_N PF00732.19 EPE27606.1 - 1.3e-47 162.6 0.2 2.2e-47 161.8 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE27606.1 - 1.9e-28 99.8 0.4 1.1e-27 97.3 0.0 2.3 3 0 0 3 3 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EPE27606.1 - 1.8e-06 27.3 1.5 5.5e-05 22.4 1.8 2.6 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE27606.1 - 1.7e-05 24.2 0.3 5.2e-05 22.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE27606.1 - 0.00014 22.0 0.1 0.00042 20.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EPE27606.1 - 0.0022 17.3 0.4 0.0055 16.0 0.1 1.8 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EPE27606.1 - 0.0026 17.4 2.5 1.3 8.5 1.4 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EPE27606.1 - 0.0028 16.4 0.6 0.0063 15.3 0.6 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 EPE27606.1 - 0.0056 16.0 0.4 0.0093 15.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 EPE27606.1 - 0.014 15.0 0.1 0.085 12.4 0.1 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ago_N_1 PF18351.1 EPE27606.1 - 0.02 15.3 0.1 0.039 14.4 0.1 1.4 1 0 0 1 1 1 0 Fungal Argonaute N-terminal domain FAD_oxidored PF12831.7 EPE27606.1 - 0.039 13.3 1.4 0.075 12.4 1.4 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EPE27606.1 - 0.32 10.0 3.0 0.85 8.6 0.3 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A zf-RING_2 PF13639.6 EPE27608.1 - 0.00091 19.5 8.3 0.0018 18.6 8.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EPE27608.1 - 0.016 15.0 5.6 0.031 14.1 5.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE27608.1 - 0.038 13.8 2.0 0.087 12.7 2.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 EPE27608.1 - 0.25 11.3 6.7 0.08 12.9 3.5 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 EPE27608.1 - 5.8 7.2 8.2 3.9 7.7 4.6 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Toprim_N PF08275.11 EPE27609.1 - 0.0082 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 DNA primase catalytic core, N-terminal domain DUF5613 PF18467.1 EPE27609.1 - 0.038 14.4 0.2 1.8 9.0 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5613) DUF2235 PF09994.9 EPE27610.1 - 1.8e-81 273.6 0.0 2.9e-81 273.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF5345 PF17280.2 EPE27611.1 - 0.52 10.3 0.1 0.52 10.3 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Lactamase_B_4 PF13691.6 EPE27617.1 - 1.2e-21 76.2 0.1 2.6e-21 75.0 0.1 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EPE27617.1 - 5.5e-15 55.4 0.1 1.2e-14 54.3 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EPE27617.1 - 0.029 14.4 0.1 0.087 12.8 0.1 1.8 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Pkinase PF00069.25 EPE27618.1 - 6.9e-53 179.7 0.0 1.3e-51 175.5 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE27618.1 - 7.3e-20 71.3 0.1 1.4e-18 67.1 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Mtc PF03820.17 EPE27619.1 - 6.4e-118 393.3 0.0 7.3e-118 393.2 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier AIM3 PF17096.5 EPE27620.1 - 0.0031 18.4 0.2 0.0031 18.4 0.2 5.6 5 1 0 5 5 5 1 Altered inheritance of mitochondria protein 3 CHAP PF05257.16 EPE27620.1 - 0.024 15.2 2.4 0.17 12.5 2.4 2.3 1 1 0 1 1 1 0 CHAP domain DUF371 PF04027.13 EPE27621.1 - 0.0068 16.4 0.3 0.15 12.1 0.0 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF371) BTB PF00651.31 EPE27622.1 - 1.2e-07 31.9 0.0 2.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain EC042_2821 PF18740.1 EPE27623.1 - 0.022 14.6 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 EC042_2821-lke REase Ribosomal_S4e PF00900.20 EPE27623.1 - 0.048 13.6 0.1 0.098 12.6 0.1 1.5 1 0 0 1 1 1 0 Ribosomal family S4e Phycobilisome PF00502.19 EPE27623.1 - 0.1 12.5 0.3 0.18 11.7 0.3 1.3 1 0 0 1 1 1 0 Phycobilisome protein YtxH PF12732.7 EPE27623.1 - 0.13 12.8 5.7 0.34 11.5 5.7 1.6 1 0 0 1 1 1 0 YtxH-like protein Herpes_BLLF1 PF05109.13 EPE27623.1 - 1.5 6.7 6.6 2.2 6.2 6.6 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) TCTP PF00838.17 EPE27625.1 - 5.9e-70 234.9 3.9 6.6e-70 234.8 3.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Tim44 PF04280.15 EPE27625.1 - 0.051 13.7 0.2 0.53 10.4 0.0 2.1 1 1 1 2 2 2 0 Tim44-like domain Ribosomal_S20p PF01649.18 EPE27625.1 - 0.13 12.9 1.0 0.23 12.1 1.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S20 FA_hydroxylase PF04116.13 EPE27626.1 - 1.3e-23 83.8 10.3 1.3e-23 83.8 10.3 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily XFP_C PF09363.10 EPE27626.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 XFP C-terminal domain Med16 PF11635.8 EPE27628.1 - 0.12 10.3 0.0 0.15 9.9 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 Cas1_AcylT PF07779.12 EPE27630.1 - 1.9e-128 429.4 18.8 2.4e-128 429.0 18.8 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p LST1 PF05083.13 EPE27630.1 - 0.039 14.2 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 LST-1 protein PC-Esterase PF13839.6 EPE27630.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p ELO PF01151.18 EPE27631.1 - 2.7e-82 276.1 7.2 3.3e-82 275.8 7.2 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Peptidase_S10 PF00450.22 EPE27632.1 - 1e-92 311.7 5.4 2.5e-92 310.5 5.4 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase CBP_CCPA PF17040.5 EPE27632.1 - 0.18 12.4 0.0 0.32 11.6 0.0 1.3 1 0 0 1 1 1 0 Cellulose-complementing protein A Peptidase_S10 PF00450.22 EPE27633.1 - 3.9e-128 428.4 0.7 5e-128 428.1 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EPE27633.1 - 1.2e-20 74.3 4.5 5.8e-20 72.1 4.5 2.0 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide SBDS_C PF09377.10 EPE27634.1 - 4.5e-45 152.4 0.0 1.1e-44 151.2 0.0 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 EPE27634.1 - 7e-33 112.6 0.0 1.3e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF627 PF04781.12 EPE27634.1 - 0.039 14.0 0.1 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Ribosomal_S13 PF00416.22 EPE27635.1 - 1.7e-54 183.6 3.0 2e-54 183.4 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EPE27635.1 - 0.016 14.0 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_L22 PF00237.19 EPE27636.1 - 7.5e-41 138.6 0.1 1.1e-40 138.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e LTD PF00932.19 EPE27636.1 - 0.11 12.8 0.0 0.18 12.2 0.0 1.4 1 1 0 1 1 1 0 Lamin Tail Domain UPF0052 PF01933.18 EPE27636.1 - 0.19 11.0 0.5 0.33 10.1 0.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0052 Amidoligase_2 PF12224.8 EPE27638.1 - 0.021 14.5 0.1 0.083 12.5 0.0 1.8 2 0 0 2 2 2 0 Putative amidoligase enzyme CorA PF01544.18 EPE27640.1 - 4.8e-06 26.1 7.4 2.9e-05 23.5 4.0 2.7 2 1 1 3 3 3 2 CorA-like Mg2+ transporter protein Alpha-2-MRAP_C PF06401.11 EPE27640.1 - 0.085 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Glyco_hydro_10 PF00331.20 EPE27641.1 - 7.4e-96 321.0 2.6 8.6e-96 320.8 2.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF2024 PF09630.10 EPE27641.1 - 0.04 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) bVLRF1 PF18826.1 EPE27641.1 - 0.042 13.7 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor GYF_2 PF14237.6 EPE27641.1 - 0.11 12.3 0.1 0.32 10.8 0.1 1.8 2 0 0 2 2 2 0 GYF domain 2 Nefa_Nip30_N PF10187.9 EPE27642.1 - 0.61 10.5 10.6 0.059 13.7 3.9 2.7 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 SUR7 PF06687.12 EPE27643.1 - 1.8e-32 112.7 13.1 2.3e-32 112.4 13.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 EPE27643.1 - 5e-05 23.1 4.6 5e-05 23.1 4.6 2.2 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.11 EPE27643.1 - 0.0047 16.8 1.0 0.0047 16.8 1.0 3.1 3 0 0 3 3 3 1 Amastin surface glycoprotein LapA_dom PF06305.11 EPE27643.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF2207 PF09972.9 EPE27643.1 - 0.56 8.9 4.3 0.092 11.5 0.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) YadA_anchor PF03895.15 EPE27643.1 - 1.3 9.1 7.7 1.9 8.7 2.6 2.4 2 0 0 2 2 2 0 YadA-like membrane anchor domain SseC PF04888.12 EPE27643.1 - 7.2 6.1 8.3 17 4.9 8.3 1.6 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family EthD PF07110.11 EPE27644.1 - 5.2e-11 43.5 0.5 9.1e-11 42.8 0.5 1.4 1 0 0 1 1 1 1 EthD domain DUF2612 PF11041.8 EPE27644.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) Ank_2 PF12796.7 EPE27645.1 - 3.8e-25 88.3 0.1 1.5e-08 35.1 0.0 4.9 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE27645.1 - 9.5e-24 83.5 1.8 1.7e-06 28.5 0.0 6.8 5 3 2 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE27645.1 - 9.2e-21 73.6 0.0 3.6e-07 30.3 0.0 5.9 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE27645.1 - 2.5e-18 64.3 2.0 0.0031 17.9 0.0 9.4 10 0 0 10 10 10 5 Ankyrin repeat Ank PF00023.30 EPE27645.1 - 3.1e-12 46.3 5.8 0.27 11.8 0.0 7.9 9 0 0 9 9 9 4 Ankyrin repeat zinc_ribbon_4 PF13717.6 EPE27646.1 - 0.019 14.9 0.1 0.043 13.7 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 EPE27646.1 - 0.024 14.4 0.3 0.053 13.3 0.3 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Thg1C PF14413.6 EPE27646.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 Thg1 C terminal domain F-box-like PF12937.7 EPE27647.1 - 8.2e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE27647.1 - 0.00076 19.3 0.0 0.002 17.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain OpgC_C PF10129.9 EPE27648.1 - 0.0062 15.5 0.4 0.0075 15.2 0.4 1.2 1 0 0 1 1 1 1 OpgC protein DPM3 PF08285.11 EPE27648.1 - 0.039 14.2 2.3 0.049 13.8 0.5 1.9 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) p450 PF00067.22 EPE27649.1 - 3.7e-21 75.4 0.0 5.3e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MF_alpha_N PF05436.11 EPE27651.1 - 0.0057 16.5 0.4 0.21 11.5 0.1 2.5 2 0 0 2 2 2 2 Mating factor alpha precursor N-terminus TLD PF07534.16 EPE27652.1 - 1.7e-10 41.3 0.0 4.1e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 TLD ABC_membrane PF00664.23 EPE27653.1 - 5.4e-87 291.9 29.8 3.9e-51 174.3 10.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EPE27653.1 - 1.5e-59 200.5 0.1 4.1e-29 101.8 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EPE27653.1 - 1.4e-14 54.0 2.5 1.4e-06 28.0 1.2 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EPE27653.1 - 3.6e-07 30.3 0.0 0.46 10.2 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EPE27653.1 - 4.5e-07 29.5 3.3 0.013 15.2 0.4 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EPE27653.1 - 5.2e-07 29.7 0.2 0.13 12.2 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 EPE27653.1 - 5.8e-07 29.9 2.6 0.2 12.0 0.0 4.2 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 EPE27653.1 - 1.6e-05 23.9 0.1 0.056 12.2 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 EPE27653.1 - 2.4e-05 24.8 0.2 0.43 10.9 0.0 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 EPE27653.1 - 7e-05 23.0 0.0 0.38 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EPE27653.1 - 0.00012 22.7 0.4 0.25 11.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 EPE27653.1 - 0.00028 20.5 1.0 0.28 10.8 0.0 3.0 4 0 0 4 4 3 2 AAA domain AAA_15 PF13175.6 EPE27653.1 - 0.0003 20.6 0.2 0.097 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.20 EPE27653.1 - 0.0015 18.4 0.2 0.44 10.4 0.0 3.4 3 0 0 3 3 3 1 Adenylylsulphate kinase SbcCD_C PF13558.6 EPE27653.1 - 0.0024 18.1 4.7 1.3 9.3 0.3 4.2 4 2 0 4 4 3 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EPE27653.1 - 0.0064 17.0 3.6 0.16 12.4 0.4 2.8 3 0 0 3 3 2 1 AAA domain DUF2075 PF09848.9 EPE27653.1 - 0.0098 15.2 0.8 0.021 14.1 0.1 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 EPE27653.1 - 0.013 15.4 0.0 1 9.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EPE27653.1 - 0.023 14.2 0.1 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EPE27653.1 - 0.024 15.0 1.7 10 6.6 0.0 3.4 4 0 0 4 4 3 0 RNA helicase FtsK_SpoIIIE PF01580.18 EPE27653.1 - 0.053 12.9 0.2 5.2 6.4 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 EPE27653.1 - 0.072 12.4 0.0 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Mg_chelatase PF01078.21 EPE27653.1 - 0.088 12.2 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 EPE27653.1 - 0.1 12.7 0.2 15 5.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 EPE27653.1 - 0.13 12.0 8.1 8.1 6.1 1.0 3.9 2 2 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EPE27653.1 - 0.19 11.5 0.1 18 5.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EPE27653.1 - 0.24 11.1 0.4 32 4.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain Polysacc_synt_4 PF04669.13 EPE27654.1 - 2.5e-24 85.9 0.5 1e-22 80.7 0.5 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis DUF2491 PF10679.9 EPE27654.1 - 0.028 13.6 0.6 0.03 13.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) AChE_tetra PF08674.10 EPE27654.1 - 0.047 13.4 3.3 0.12 12.1 3.3 1.6 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain WD40 PF00400.32 EPE27656.1 - 8.5e-10 39.1 13.9 0.2 12.6 0.0 9.1 10 0 0 10 10 10 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE27656.1 - 1.1e-08 35.3 0.0 0.16 12.3 0.0 6.6 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPE27656.1 - 2.2e-06 26.9 0.0 0.00015 20.8 0.0 2.7 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 EPE27656.1 - 0.0025 17.4 0.1 0.024 14.2 0.1 2.6 1 1 0 1 1 1 1 PQQ-like domain Frtz PF11768.8 EPE27656.1 - 0.15 10.4 0.0 0.24 9.7 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Alpha-amylase PF00128.24 EPE27657.1 - 2.8e-108 362.5 0.1 4.2e-108 361.9 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EPE27657.1 - 0.00061 19.9 0.0 0.0018 18.4 0.0 1.9 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 EPE27657.1 - 0.0013 17.9 0.0 0.0029 16.7 0.0 1.5 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 EPE27657.1 - 0.044 14.1 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Glyco_hydro_32N PF00251.20 EPE27658.1 - 3.1e-43 148.5 0.0 4.4e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EPE27658.1 - 1.6e-27 96.5 0.1 2.5e-27 95.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 EPE27658.1 - 1.2e-07 32.0 0.0 1.9e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) Glyco_hydro_43 PF04616.14 EPE27658.1 - 0.0045 16.3 0.1 0.52 9.6 0.1 2.6 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 DUF4185 PF13810.6 EPE27658.1 - 0.024 13.9 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) RBM1CTR PF08081.11 EPE27658.1 - 0.12 12.5 0.2 0.4 10.8 0.2 1.9 1 0 0 1 1 1 0 RBM1CTR (NUC064) family Sugar_tr PF00083.24 EPE27659.1 - 1.4e-81 274.7 20.2 1.7e-81 274.4 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE27659.1 - 2.3e-22 79.4 25.0 2.3e-22 79.4 25.0 2.0 2 1 1 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE27659.1 - 2.4e-05 23.0 0.8 3.8e-05 22.3 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EPE27659.1 - 0.0093 14.4 8.9 0.024 13.0 1.1 2.5 3 0 0 3 3 3 2 Transmembrane secretion effector WD40 PF00400.32 EPE27660.1 - 7.5e-15 55.1 15.3 0.0004 21.1 0.2 5.8 6 1 0 6 6 6 4 WD domain, G-beta repeat WD40_like PF17005.5 EPE27660.1 - 1.7e-10 40.8 0.1 1.1e-06 28.3 0.0 3.3 2 1 0 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 EPE27660.1 - 1.1e-06 28.9 3.5 0.0034 17.7 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EPE27660.1 - 1.8e-06 28.2 4.0 0.39 11.3 0.2 5.3 5 0 0 5 5 5 1 PQQ-like domain PQQ_2 PF13360.6 EPE27660.1 - 0.00013 21.7 1.7 0.0016 18.1 1.4 3.0 1 1 0 1 1 1 1 PQQ-like domain BBS2_Mid PF14783.6 EPE27660.1 - 0.00027 21.0 0.2 0.86 9.7 0.1 2.7 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region YajC PF02699.15 EPE27660.1 - 0.0003 20.6 0.5 12 5.9 0.5 4.1 2 1 1 3 3 3 1 Preprotein translocase subunit PALB2_WD40 PF16756.5 EPE27660.1 - 0.011 14.6 0.5 2.2 7.1 0.0 3.4 1 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 EPE27660.1 - 0.018 13.7 1.7 1.6 7.2 0.0 3.3 1 1 2 3 3 3 0 Nucleoporin Nup120/160 eIF2A PF08662.11 EPE27660.1 - 0.087 12.7 0.0 0.93 9.3 0.0 2.4 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A SHD1 PF03983.12 EPE27660.1 - 0.11 12.4 0.1 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 SLA1 homology domain 1, SHD1 Saw1 PF11561.8 EPE27661.1 - 0.0066 16.0 0.8 0.037 13.6 0.5 2.1 2 0 0 2 2 2 1 Single strand annealing-weakened 1 DUF3978 PF13123.6 EPE27661.1 - 0.13 12.0 0.4 0.23 11.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3978) Pyr_redox_2 PF07992.14 EPE27662.1 - 1.4e-38 132.8 0.0 5.9e-35 120.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE27662.1 - 2.1e-09 37.8 0.0 4.1e-07 30.5 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE27662.1 - 0.00042 20.0 0.1 0.54 9.8 0.0 3.5 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE27662.1 - 0.0063 16.7 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EPE27662.1 - 0.043 13.1 0.0 2.6 7.2 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S5 PF00333.20 EPE27664.1 - 2.6e-27 94.6 1.9 1.2e-26 92.5 0.7 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EPE27664.1 - 1.6e-23 81.9 0.0 2.6e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FXMRP1_C_core PF12235.8 EPE27664.1 - 3.7 8.2 8.6 6.4 7.4 8.6 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Zn_clus PF00172.18 EPE27665.1 - 3.3e-08 33.5 7.4 6.8e-08 32.5 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE27665.1 - 2.3e-05 23.4 3.7 7.3e-05 21.7 3.7 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain UPF0242 PF06785.11 EPE27666.1 - 0.025 14.7 16.9 0.099 12.7 4.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 EPE27666.1 - 0.17 10.7 10.0 0.23 10.3 10.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Shugoshin_N PF07558.11 EPE27668.1 - 0.00074 19.3 5.1 0.0023 17.7 5.1 1.9 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Sigma70_ECF PF07638.11 EPE27668.1 - 0.44 10.4 5.2 0.9 9.4 5.2 1.4 1 0 0 1 1 1 0 ECF sigma factor Nsp1_C PF05064.13 EPE27668.1 - 1.2 9.0 13.6 0.04 13.7 2.1 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region UPF0184 PF03670.13 EPE27669.1 - 0.042 14.2 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Zn_clus PF00172.18 EPE27670.1 - 5.9e-10 39.1 14.2 9.5e-10 38.4 14.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE27670.1 - 4e-09 35.9 0.3 9.1e-09 34.7 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain FA_hydroxylase PF04116.13 EPE27670.1 - 0.00032 21.0 0.6 0.00032 21.0 0.6 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DSPc PF00782.20 EPE27672.1 - 6.5e-23 81.0 0.0 7.8e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EPE27672.1 - 0.15 11.7 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Tom37 PF10568.9 EPE27673.1 - 3.7e-37 127.4 0.0 5.4e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EPE27673.1 - 1.1e-08 34.7 0.2 2.6e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EPE27673.1 - 4.7e-06 27.3 0.0 2.3e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain NACHT PF05729.12 EPE27675.1 - 1.2e-07 31.8 0.0 3.6e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EPE27675.1 - 0.00082 19.7 0.8 0.22 11.8 0.0 4.0 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 EPE27675.1 - 0.064 13.7 0.0 0.25 11.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase SNF2_N PF00176.23 EPE27676.1 - 1e-68 231.6 0.3 2e-68 230.7 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE27676.1 - 1.8e-11 44.3 0.0 4.6e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE27676.1 - 2e-06 27.9 0.2 9.3e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EPE27676.1 - 0.00023 21.0 0.0 0.00057 19.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EPE27676.1 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.7 1 1 0 1 1 1 1 SWI2/SNF2 ATPase tRNA-synt_1 PF00133.22 EPE27677.1 - 1e-151 506.2 0.0 1.4e-151 505.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EPE27677.1 - 1.4e-19 70.5 0.0 2.5e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EPE27677.1 - 1.4e-18 66.9 0.1 8.5e-10 37.9 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 EPE27677.1 - 4.3 7.3 7.7 21 5.1 7.7 2.1 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS UPF0183 PF03676.14 EPE27678.1 - 8.9e-57 193.2 0.0 2.4e-35 122.6 0.0 3.1 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0183) Kinesin PF00225.23 EPE27679.1 - 9.9e-109 363.3 0.1 2.4e-108 362.0 0.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EPE27679.1 - 9.7e-25 87.3 0.5 6.3e-24 84.6 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 EPE27679.1 - 5.5e-08 33.3 0.1 5.5e-08 33.3 0.1 5.3 5 0 0 5 5 5 1 Kinesin-associated microtubule-binding CIDE-N PF02017.15 EPE27679.1 - 0.068 13.2 1.5 3.1 7.9 0.9 2.9 2 0 0 2 2 2 0 CIDE-N domain Gp-FAR-1 PF05823.12 EPE27679.1 - 0.41 11.0 12.2 3.2 8.1 1.4 4.2 3 2 1 4 4 4 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Baculo_PEP_C PF04513.12 EPE27679.1 - 4.6 7.3 24.8 0.52 10.4 0.8 5.9 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3425 PF11905.8 EPE27680.1 - 1.2e-15 57.5 2.5 3.2e-15 56.2 2.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EPE27680.1 - 0.00017 21.6 18.1 0.00036 20.6 18.1 1.5 1 1 0 1 1 1 1 bZIP transcription factor DUF3560 PF12083.8 EPE27680.1 - 0.078 13.1 5.3 0.13 12.4 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3560) FlxA PF14282.6 EPE27680.1 - 0.19 11.7 6.9 0.45 10.5 6.9 1.6 1 1 0 1 1 1 0 FlxA-like protein bZIP_2 PF07716.15 EPE27680.1 - 0.2 11.8 22.9 0.18 11.9 13.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper YabA PF06156.13 EPE27680.1 - 0.22 12.2 2.5 0.49 11.1 2.5 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Macoilin PF09726.9 EPE27680.1 - 1.4 7.3 6.6 2 6.9 6.6 1.1 1 0 0 1 1 1 0 Macoilin family TSC22 PF01166.18 EPE27680.1 - 6.7 7.1 7.6 1.9e+02 2.5 7.6 2.5 1 1 0 1 1 1 0 TSC-22/dip/bun family Dynamin_N PF00350.23 EPE27681.1 - 3.6e-30 105.2 0.2 9.3e-30 103.9 0.0 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 EPE27681.1 - 1.8e-28 99.6 0.0 5.9e-27 94.6 0.0 2.7 1 1 1 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EPE27681.1 - 0.00011 22.2 0.0 0.0014 18.7 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Glyco_hydro_4C PF11975.8 EPE27681.1 - 0.011 15.9 1.3 0.023 14.8 1.3 1.5 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain AAA_23 PF13476.6 EPE27681.1 - 0.013 16.0 0.5 8.1 6.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 EPE27681.1 - 0.039 13.7 3.3 0.79 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EPE27681.1 - 0.044 14.3 0.3 2.6 8.6 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EPE27681.1 - 0.068 13.4 0.0 0.27 11.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EPE27681.1 - 0.069 13.5 0.0 2.8 8.3 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain EF-hand_2 PF09068.11 EPE27681.1 - 0.086 13.0 1.1 2.7 8.2 0.3 2.4 2 0 0 2 2 2 0 EF hand Vps62 PF06101.11 EPE27682.1 - 5.4e-11 41.5 0.2 5.4e-11 41.5 0.2 1.5 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 zf-MYND PF01753.18 EPE27683.1 - 7.1e-08 32.4 10.7 7.1e-08 32.4 10.7 1.9 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 EPE27683.1 - 0.97 9.6 5.7 2.4 8.3 5.7 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF4106 PF13388.6 EPE27683.1 - 1.7 7.8 5.0 2.5 7.2 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF953 PF06110.11 EPE27684.1 - 1.2e-20 73.3 0.1 1.4e-20 73.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 EPE27684.1 - 0.00048 20.1 0.0 0.0006 19.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EPE27684.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 EPE27684.1 - 0.076 12.8 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin TauD PF02668.16 EPE27685.1 - 8.4e-60 202.8 0.6 1.2e-59 202.4 0.6 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4350 PF14258.6 EPE27685.1 - 0.1 13.0 0.0 0.37 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Na_Ca_ex_C PF16494.5 EPE27686.1 - 0.05 14.1 0.0 0.19 12.2 0.0 2.0 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain zf-CCHC PF00098.23 EPE27687.1 - 1.4e-38 129.2 57.0 4.4e-09 36.0 3.0 6.3 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.6 EPE27687.1 - 1.4e-06 28.2 34.4 0.0098 15.8 0.4 5.0 3 1 2 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.6 EPE27687.1 - 3.3e-06 26.7 31.0 0.3 10.9 0.3 6.2 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.6 EPE27687.1 - 0.03 14.2 37.6 0.055 13.3 2.1 6.1 5 1 1 6 6 6 0 Zinc knuckle zf-CCHC_5 PF14787.6 EPE27687.1 - 0.1 12.3 28.4 1.7 8.4 1.2 5.3 4 1 1 5 5 5 0 GAG-polyprotein viral zinc-finger Kinesin PF00225.23 EPE27688.1 - 1.2e-110 369.6 0.9 2.4e-110 368.6 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.8 EPE27688.1 - 7.9e-45 153.3 0.0 9e-44 149.8 0.0 2.7 2 0 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 EPE27688.1 - 3.7e-37 128.2 19.5 1.4e-30 106.8 0.2 4.0 3 1 1 4 4 4 3 Kinesin-associated Microtub_bd PF16796.5 EPE27688.1 - 4.5e-24 85.1 0.0 1.8e-23 83.2 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 EPE27688.1 - 1.4e-06 28.7 1.1 1.4e-06 28.7 1.1 2.3 2 0 0 2 2 2 1 Kinesin protein 1B PH PF00169.29 EPE27688.1 - 5e-05 23.8 0.0 0.00019 21.9 0.0 1.9 2 0 0 2 2 1 1 PH domain Yop-YscD_cpl PF16697.5 EPE27688.1 - 0.073 13.4 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain UPF0242 PF06785.11 EPE27688.1 - 0.22 11.6 17.5 1.3 9.1 1.5 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Zw10 PF06248.13 EPE27688.1 - 0.94 8.0 11.6 0.12 10.9 5.7 2.1 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 Rab5-bind PF09311.11 EPE27688.1 - 1.4 8.2 22.3 0.26 10.6 12.6 3.1 3 0 0 3 3 3 0 Rabaptin-like protein Exonuc_VII_L PF02601.15 EPE27688.1 - 5.6 6.4 9.8 10 5.6 6.1 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF2196 PF09962.9 EPE27689.1 - 2.5e-23 81.8 2.0 4.2e-23 81.1 2.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) MFS_1 PF07690.16 EPE27690.1 - 1.6e-36 125.9 52.8 1.6e-36 125.9 52.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE27690.1 - 0.0021 17.0 32.7 0.003 16.5 1.4 3.6 3 1 1 4 4 4 3 Sugar (and other) transporter PIRT PF15099.6 EPE27690.1 - 3.4 7.2 4.7 4.7 6.8 0.6 3.0 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family ArsA_ATPase PF02374.15 EPE27691.1 - 1e-111 373.0 0.0 1.1e-111 372.8 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EPE27691.1 - 5.2e-15 55.8 0.0 7e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EPE27691.1 - 1.3e-12 47.9 0.0 2.1e-12 47.2 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EPE27691.1 - 3.5e-07 29.9 0.4 0.00028 20.4 0.0 2.6 3 0 0 3 3 3 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EPE27691.1 - 6.9e-06 25.7 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EPE27691.1 - 7.6e-05 22.4 0.0 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 EPE27691.1 - 9.9e-05 21.9 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 EPE27691.1 - 0.036 14.4 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EPE27691.1 - 0.038 13.6 0.1 0.064 12.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EPE27691.1 - 0.11 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Tir_receptor_N PF07490.11 EPE27691.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Zeta_toxin PF06414.12 EPE27691.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 EPE27691.1 - 0.15 12.4 0.0 2.8 8.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Transthyretin PF00576.21 EPE27692.1 - 3.5e-32 111.3 0.0 5.3e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 EPE27692.1 - 0.0092 16.2 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain GMC_oxred_N PF00732.19 EPE27694.1 - 1.7e-49 168.8 0.0 2.7e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE27694.1 - 1.8e-37 129.1 0.0 2.7e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EPE27694.1 - 2.7e-07 30.5 3.5 5.9e-06 26.1 3.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPE27694.1 - 2.1e-06 27.1 1.3 0.026 13.6 1.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EPE27694.1 - 3.7e-05 23.1 0.9 0.047 12.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPE27694.1 - 0.0032 16.7 0.2 0.014 14.7 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE27694.1 - 0.0039 16.3 0.2 0.0077 15.3 0.2 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPE27694.1 - 0.012 15.8 2.4 0.037 14.3 2.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EPE27694.1 - 0.072 11.8 0.7 0.12 11.1 0.7 1.2 1 0 0 1 1 1 0 HI0933-like protein Chlamy_scaf PF09675.10 EPE27694.1 - 0.1 12.9 0.0 1.7 9.0 0.0 2.2 2 0 0 2 2 2 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) Pyr_redox PF00070.27 EPE27694.1 - 0.2 12.3 1.2 6.8 7.3 1.4 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.22 EPE27695.1 - 1.6e-123 412.6 0.6 1.8e-123 412.5 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Hyphal_reg_CWP PF11765.8 EPE27695.1 - 0.048 12.6 0.1 5 6.0 0.0 2.2 1 1 1 2 2 2 0 Hyphally regulated cell wall protein N-terminal LuxC PF05893.14 EPE27695.1 - 0.071 12.1 0.5 0.11 11.6 0.5 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) CDT1_C PF16679.5 EPE27697.1 - 7.2e-23 80.8 0.2 1.9e-22 79.5 0.2 1.8 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain MBF1 PF08523.10 EPE27698.1 - 5.7e-28 97.2 1.0 9.5e-28 96.5 1.0 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EPE27698.1 - 7.6e-10 38.7 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix MRP-L27 PF09809.9 EPE27698.1 - 0.0009 19.1 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 HTH_31 PF13560.6 EPE27698.1 - 0.0081 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain ERAP1_C PF11838.8 EPE27699.1 - 3.2e-85 286.5 0.1 3.2e-84 283.1 0.0 2.4 2 1 1 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EPE27699.1 - 9.7e-85 283.6 1.0 1.7e-84 282.8 1.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EPE27699.1 - 1.6e-49 168.7 4.7 2.5e-49 168.0 3.4 2.0 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Mnd1 PF03962.15 EPE27700.1 - 1.1e-24 86.5 0.0 1.7e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Mnd1 HTH domain CENP-F_leu_zip PF10473.9 EPE27700.1 - 0.004 17.2 0.2 0.0069 16.4 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LZ3wCH PF18517.1 EPE27700.1 - 0.074 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Leucine zipper with capping helix domain Spc7 PF08317.11 EPE27700.1 - 0.19 10.6 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Arrestin_N PF00339.29 EPE27701.1 - 2.9e-19 69.6 0.0 5.4e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EPE27701.1 - 9.2e-09 35.9 0.0 0.0017 18.8 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain FA_desaturase PF00487.24 EPE27702.1 - 7.9e-23 81.6 19.1 1.8e-22 80.4 19.1 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EPE27702.1 - 1.8e-07 31.4 0.0 1.4e-06 28.6 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3474) Mitoc_mL59 PF18126.1 EPE27703.1 - 1.9e-42 144.6 2.7 3.1e-42 143.9 2.7 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 DEAD PF00270.29 EPE27704.1 - 9e-47 159.1 0.0 2.2e-46 157.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE27704.1 - 1.5e-28 99.4 0.0 1e-27 96.7 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE27704.1 - 0.0003 20.8 0.0 0.00062 19.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3334 PF11813.8 EPE27704.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) PRAI PF00697.22 EPE27704.1 - 0.093 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF2986 PF11661.8 EPE27704.1 - 0.69 10.5 11.5 0.2 12.2 4.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Glyco_hydro_61 PF03443.14 EPE27705.1 - 5e-57 193.2 0.0 6.2e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 zf-C2H2 PF00096.26 EPE27707.1 - 9.6e-13 47.8 16.4 3.4e-06 27.2 2.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE27707.1 - 6.5e-08 32.8 11.9 0.001 19.7 1.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPE27707.1 - 5.4e-07 29.7 13.4 1.1e-05 25.6 6.2 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EPE27707.1 - 4.1e-06 26.9 4.9 0.0037 17.5 0.6 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPE27707.1 - 6.2e-05 23.3 8.9 0.00031 21.0 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EPE27707.1 - 0.00025 20.9 11.2 0.026 14.5 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 EPE27707.1 - 0.12 12.1 5.4 2.1 8.1 0.6 2.6 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_UBZ PF18439.1 EPE27707.1 - 0.23 11.1 3.0 6 6.5 0.4 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger SPT6_acidic PF14632.6 EPE27707.1 - 0.35 11.5 8.5 0.16 12.6 3.5 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 zf-C2H2_11 PF16622.5 EPE27707.1 - 0.35 10.7 7.8 1.7 8.5 0.2 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 EPE27707.1 - 1 9.4 7.0 0.61 10.2 3.1 2.3 1 1 1 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.10 EPE27707.1 - 1.6 8.9 5.0 8.1 6.6 0.8 2.5 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2HE PF16278.5 EPE27707.1 - 3.5 8.1 6.7 32 5.1 6.7 2.4 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 EPE27707.1 - 5.2 7.8 6.4 6.1 7.5 0.6 2.7 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats Diphthami_syn_2 PF01902.17 EPE27708.1 - 1e-26 93.8 0.0 3.2e-26 92.2 0.0 1.8 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EPE27708.1 - 2.7e-13 50.0 0.0 1.5e-07 31.4 0.0 3.1 3 0 0 3 3 3 2 Endoribonuclease L-PSP QueC PF06508.13 EPE27708.1 - 0.026 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC AAA_11 PF13086.6 EPE27709.1 - 7.1e-60 203.0 0.0 1.6e-59 201.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EPE27709.1 - 5e-48 163.4 0.0 1.1e-47 162.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPE27709.1 - 5.6e-13 49.0 0.0 7.6e-12 45.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPE27709.1 - 3.9e-08 33.8 0.0 1.5e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EPE27709.1 - 2.7e-05 23.6 0.5 0.00017 21.0 0.4 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 EPE27709.1 - 0.00022 20.8 0.0 0.00042 19.9 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EPE27709.1 - 0.00028 20.8 0.0 0.18 11.6 0.0 2.6 2 0 0 2 2 2 1 Helicase ResIII PF04851.15 EPE27709.1 - 0.00069 19.7 0.0 0.0024 17.9 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 EPE27709.1 - 0.0008 19.2 0.1 1.4 8.6 0.0 2.9 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 EPE27709.1 - 0.0023 17.8 0.0 0.016 14.9 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.6 EPE27709.1 - 0.0031 17.1 0.3 0.017 14.7 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EPE27709.1 - 0.0034 17.8 0.0 0.0076 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPE27709.1 - 0.0038 17.5 0.3 0.022 15.0 0.3 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EPE27709.1 - 0.0042 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.16 EPE27709.1 - 0.0054 16.2 0.9 0.2 11.1 0.0 3.1 4 0 0 4 4 3 1 PhoH-like protein Flavi_DEAD PF07652.14 EPE27709.1 - 0.01 15.8 0.0 0.031 14.3 0.0 1.8 1 0 0 1 1 1 0 Flavivirus DEAD domain T2SSE PF00437.20 EPE27709.1 - 0.011 14.8 0.0 0.029 13.4 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.14 EPE27709.1 - 0.019 14.1 0.0 3.9 6.5 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase TrwB_AAD_bind PF10412.9 EPE27709.1 - 0.023 13.6 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 EPE27709.1 - 0.03 14.0 0.0 0.08 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EPE27709.1 - 0.037 14.5 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CpcD PF01383.21 EPE27709.1 - 0.051 13.8 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 CpcD/allophycocyanin linker domain AAA_10 PF12846.7 EPE27709.1 - 0.098 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_5 PF07728.14 EPE27709.1 - 0.1 12.6 0.1 0.92 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UvrD_C PF13361.6 EPE27709.1 - 0.14 11.5 0.1 0.4 10.0 0.0 1.7 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain FemAB_like PF04339.12 EPE27709.1 - 0.21 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition XkdW PF09636.10 EPE27710.1 - 0.029 14.4 0.1 0.13 12.3 0.1 2.1 2 0 0 2 2 2 0 XkdW protein Fib_alpha PF08702.10 EPE27710.1 - 0.073 13.3 1.4 0.58 10.3 0.1 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family MbeD_MobD PF04899.12 EPE27710.1 - 0.15 12.2 1.9 4.7 7.4 0.1 2.5 2 0 0 2 2 2 0 MbeD/MobD like CLZ PF16526.5 EPE27710.1 - 1.9 8.9 4.0 13 6.2 0.6 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SUN PF03856.13 EPE27711.1 - 7e-90 300.8 13.7 8.8e-90 300.4 13.7 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF908 PF06012.12 EPE27711.1 - 1.1 8.6 3.3 1.5 8.2 3.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PRCC PF10253.9 EPE27711.1 - 2 9.2 5.2 2.9 8.6 5.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Neisseria_TspB PF05616.13 EPE27711.1 - 4.4 5.7 7.2 6.2 5.2 7.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF202 PF02656.15 EPE27712.1 - 2.4e-21 75.9 5.5 2.4e-21 75.9 5.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) JSRP PF15312.6 EPE27712.1 - 0.15 12.0 1.3 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 Junctional sarcoplasmic reticulum protein DUF2205 PF10224.9 EPE27713.1 - 3.6e-37 126.2 0.6 6.1e-37 125.5 0.6 1.4 1 0 0 1 1 1 1 Short coiled-coil protein TACC_C PF05010.14 EPE27713.1 - 0.002 18.0 1.5 0.0027 17.5 1.5 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal KASH_CCD PF14662.6 EPE27713.1 - 0.012 15.5 1.2 0.017 14.9 1.2 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4208 PF13907.6 EPE27713.1 - 0.058 13.8 0.4 0.086 13.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) NDUF_B8 PF05821.11 EPE27715.1 - 2.8e-08 33.8 0.5 4.4e-08 33.2 0.5 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 EPE27716.1 - 6.6e-66 222.4 0.3 1e-65 221.7 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE27716.1 - 1.2e-19 70.7 0.0 7.6e-19 68.1 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE27716.1 - 8.5e-10 38.9 0.6 3.8e-09 36.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EPE27716.1 - 0.00069 18.9 0.3 0.2 10.8 0.1 2.5 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 AAA_25 PF13481.6 EPE27716.1 - 0.034 13.7 0.5 1.2 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain HSA PF07529.13 EPE27716.1 - 0.083 13.2 11.3 0.51 10.7 11.3 2.5 1 1 0 1 1 1 0 HSA TRAPPC10 PF12584.8 EPE27717.1 - 1.8e-34 118.7 0.0 6.5e-34 116.9 0.0 2.0 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 MBOAT_2 PF13813.6 EPE27717.1 - 2.5e-14 53.3 0.1 6.5e-14 52.0 0.1 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Foie-gras_1 PF11817.8 EPE27717.1 - 2.2e-06 27.5 0.2 4.4e-06 26.5 0.2 1.5 1 0 0 1 1 1 1 Foie gras liver health family 1 Claudin_2 PF13903.6 EPE27718.1 - 0.059 13.1 2.2 0.07 12.9 2.2 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction BTB PF00651.31 EPE27719.1 - 0.0055 16.9 0.0 0.024 14.9 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain Gpr1_Fun34_YaaH PF01184.19 EPE27721.1 - 2e-91 305.2 19.6 2.3e-91 305.0 19.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2393 PF09624.10 EPE27721.1 - 0.6 10.1 2.1 1.2 9.1 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) Fungal_trans_2 PF11951.8 EPE27722.1 - 0.0013 17.6 2.9 0.0013 17.6 2.9 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain GMC_oxred_N PF00732.19 EPE27723.1 - 1.4e-55 188.7 0.0 1.9e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE27723.1 - 2.2e-32 112.6 0.0 4.1e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 EPE27723.1 - 0.00023 20.5 0.0 0.039 13.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE27723.1 - 0.0003 20.0 0.2 0.11 11.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EPE27723.1 - 0.0024 17.5 0.1 0.091 12.3 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EPE27723.1 - 0.0025 16.9 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EPE27723.1 - 0.0042 16.4 0.0 0.072 12.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE27723.1 - 0.022 15.0 0.2 0.063 13.5 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 EPE27723.1 - 0.027 14.7 0.2 0.083 13.2 0.2 1.8 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 EPE27723.1 - 0.054 12.2 0.1 0.85 8.2 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EPE27723.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TLD PF07534.16 EPE27724.1 - 3.5e-29 101.8 0.0 7.9e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 EPE27724.1 - 2.9e-16 60.2 0.7 2.9e-16 60.2 0.7 1.9 2 0 0 2 2 2 1 Domain of unknown function HIG_1_N PF04588.13 EPE27725.1 - 3.4e-22 78.4 1.1 4e-22 78.2 0.1 1.6 2 0 0 2 2 2 1 Hypoxia induced protein conserved region Phage_Gp23 PF10669.9 EPE27725.1 - 0.016 15.5 3.1 0.022 15.1 3.1 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF2514 PF10721.9 EPE27725.1 - 0.026 14.5 2.4 0.038 14.0 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) KorB PF08535.10 EPE27725.1 - 0.027 14.5 0.1 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 KorB domain MAS20 PF02064.15 EPE27725.1 - 0.061 13.4 1.4 0.092 12.8 1.4 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor PALP PF00291.25 EPE27726.1 - 1e-78 264.7 0.4 1.2e-78 264.5 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EPE27726.1 - 2.3e-41 139.4 0.0 4.2e-21 74.5 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HU-HIG PF18291.1 EPE27726.1 - 0.15 12.2 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Ribosomal_L36 PF00444.18 EPE27727.1 - 8.9e-21 73.8 9.2 1.2e-20 73.4 9.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Acetyltransf_1 PF00583.25 EPE27728.1 - 5.4e-12 46.0 0.0 7.2e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE27728.1 - 3.5e-08 33.7 0.0 5.4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE27728.1 - 1.4e-06 28.2 0.0 2.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EPE27728.1 - 2.6e-06 27.4 0.0 3.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EPE27728.1 - 0.00045 20.9 0.0 0.00063 20.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EPE27728.1 - 0.0063 16.7 0.0 0.023 14.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPE27728.1 - 0.17 12.0 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 EPE27728.1 - 0.17 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PLAC8 PF04749.17 EPE27729.1 - 2.5e-21 76.5 7.2 3e-21 76.3 7.2 1.1 1 0 0 1 1 1 1 PLAC8 family Cyclin_N PF00134.23 EPE27731.1 - 4.8e-37 126.6 2.1 5.2e-37 126.4 0.6 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EPE27731.1 - 9.7e-11 41.8 0.5 2.6e-10 40.4 0.5 1.8 1 1 0 1 1 1 1 Cyclin, C-terminal domain DUF3746 PF12562.8 EPE27732.1 - 0.018 14.9 0.2 0.036 14.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) Tropomyosin_1 PF12718.7 EPE27735.1 - 0.044 13.9 0.5 2.2 8.4 0.2 2.6 3 0 0 3 3 3 0 Tropomyosin like Tropomyosin PF00261.20 EPE27735.1 - 0.087 12.2 2.1 0.15 11.4 0.4 2.2 3 0 0 3 3 3 0 Tropomyosin DUF2630 PF10944.8 EPE27735.1 - 0.11 12.9 2.6 1.1 9.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) F-box PF00646.33 EPE27736.1 - 0.02 14.8 0.0 0.91 9.5 0.0 2.7 2 0 0 2 2 2 0 F-box domain NCBP3 PF10309.9 EPE27738.1 - 2.4e-24 85.0 0.1 3.9e-24 84.3 0.1 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 EPE27738.1 - 0.088 12.8 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 RNA binding domain FA_desaturase_2 PF03405.14 EPE27739.1 - 0.019 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Myb_DNA-bind_4 PF13837.6 EPE27739.1 - 0.15 12.5 3.3 0.12 12.8 0.9 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ureidogly_lyase PF04115.12 EPE27740.1 - 1.8e-63 213.7 0.0 2.2e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase AAA PF00004.29 EPE27741.1 - 7.2e-97 320.9 0.0 3.9e-47 160.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPE27741.1 - 1.6e-24 85.4 4.8 2.4e-13 49.7 0.4 2.7 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EPE27741.1 - 2.4e-19 69.3 1.1 7e-19 67.8 0.4 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EPE27741.1 - 1.3e-13 51.0 0.0 1.9e-05 24.4 0.0 3.3 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EPE27741.1 - 1.6e-13 51.2 0.0 2.6e-07 30.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EPE27741.1 - 2.8e-12 47.0 0.0 1.1e-05 25.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EPE27741.1 - 8.2e-12 45.8 0.0 0.00012 22.6 0.0 4.4 3 2 0 3 3 2 2 AAA ATPase domain AAA_5 PF07728.14 EPE27741.1 - 5.4e-11 42.6 0.4 1.5e-05 25.0 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EPE27741.1 - 4.2e-09 36.1 0.0 0.0017 17.6 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 EPE27741.1 - 7.6e-09 36.0 0.4 0.068 13.4 0.0 4.4 2 2 2 4 4 4 2 AAA domain CDC48_2 PF02933.17 EPE27741.1 - 4.8e-08 32.7 0.0 1.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 EPE27741.1 - 5.7e-07 29.1 0.2 0.037 13.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EPE27741.1 - 6e-07 29.4 0.0 0.046 13.5 0.0 3.0 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 EPE27741.1 - 1.6e-06 28.7 0.0 0.04 14.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EPE27741.1 - 1.9e-06 28.0 0.0 0.02 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 EPE27741.1 - 2.8e-06 26.9 0.2 0.61 9.4 0.0 3.5 3 0 0 3 3 3 2 KaiC RNA_helicase PF00910.22 EPE27741.1 - 2.9e-06 27.6 0.0 0.041 14.3 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_7 PF12775.7 EPE27741.1 - 3.5e-06 26.7 0.1 0.034 13.7 0.0 3.0 2 2 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 EPE27741.1 - 2.4e-05 24.3 0.2 0.00016 21.6 0.1 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.13 EPE27741.1 - 2.7e-05 23.5 0.0 0.015 14.5 0.0 2.8 3 0 0 3 3 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EPE27741.1 - 3.9e-05 23.4 0.0 0.39 10.4 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 EPE27741.1 - 4.6e-05 23.7 0.1 0.33 11.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 EPE27741.1 - 5.5e-05 23.7 0.0 0.33 11.5 0.0 3.3 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.16 EPE27741.1 - 6.4e-05 22.5 0.1 0.4 10.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_25 PF13481.6 EPE27741.1 - 6.4e-05 22.6 4.9 1.5 8.3 0.0 4.8 3 2 2 5 5 5 1 AAA domain Parvo_NS1 PF01057.17 EPE27741.1 - 8.2e-05 21.8 0.0 0.082 12.0 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 EPE27741.1 - 0.00014 21.7 0.0 0.77 9.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.6 EPE27741.1 - 0.0003 21.2 0.0 0.88 10.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 EPE27741.1 - 0.00035 20.5 0.0 0.86 9.4 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_3 PF07726.11 EPE27741.1 - 0.00054 19.8 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EPE27741.1 - 0.00072 19.5 0.0 0.65 10.0 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 EPE27741.1 - 0.00075 19.5 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EPE27741.1 - 0.00075 19.4 0.1 1.2 8.8 0.0 2.6 3 0 0 3 3 2 2 AAA domain DUF2075 PF09848.9 EPE27741.1 - 0.0016 17.8 0.0 0.68 9.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EPE27741.1 - 0.0022 17.7 0.3 2.5 7.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EPE27741.1 - 0.0051 16.6 0.0 0.67 9.6 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EPE27741.1 - 0.0057 17.0 0.4 9.3 6.6 0.0 3.4 3 1 1 4 4 2 0 AAA domain ATPase_2 PF01637.18 EPE27741.1 - 0.0062 16.5 0.0 10 5.9 0.0 3.6 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 EPE27741.1 - 0.0079 16.3 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 EPE27741.1 - 0.01 15.7 0.1 3 7.7 0.0 2.9 3 0 0 3 3 3 0 NACHT domain IPT PF01745.16 EPE27741.1 - 0.016 14.7 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UFD1 PF03152.14 EPE27741.1 - 0.016 14.7 0.0 0.14 11.6 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 KAP_NTPase PF07693.14 EPE27741.1 - 0.02 14.1 0.0 0.91 8.7 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain NB-ARC PF00931.22 EPE27741.1 - 0.023 13.9 0.0 1.6 7.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 EPE27741.1 - 0.032 13.5 0.0 7.4 5.8 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 EPE27741.1 - 0.048 13.6 2.7 3.3 7.6 0.0 4.1 5 0 0 5 5 4 0 NTPase Cytidylate_kin2 PF13189.6 EPE27741.1 - 0.07 13.3 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family Zot PF05707.12 EPE27741.1 - 0.18 11.5 0.0 10 5.7 0.0 2.9 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_6 PF12774.7 EPE27741.1 - 0.21 10.5 0.0 8.4 5.2 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region eIF-1a PF01176.19 EPE27741.1 - 0.21 11.4 1.0 1.5 8.6 0.3 2.5 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 PTPLA PF04387.14 EPE27742.1 - 1.8e-58 196.9 10.6 1.8e-58 196.9 10.6 1.4 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Glyco_hydro_71 PF03659.14 EPE27746.1 - 2.4e-81 273.5 1.3 2.8e-81 273.2 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 LSM PF01423.22 EPE27748.1 - 1.5e-14 53.4 0.2 2.6e-14 52.6 0.2 1.4 1 0 0 1 1 1 1 LSM domain Adaptin_binding PF10199.9 EPE27748.1 - 4.3e-14 53.2 3.7 1.1e-13 51.9 3.7 1.7 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Rx_N PF18052.1 EPE27748.1 - 0.095 13.0 1.0 3.8 7.8 0.2 2.5 2 0 0 2 2 2 0 Rx N-terminal domain PGP_phosphatase PF09419.10 EPE27749.1 - 4e-59 199.0 0.0 4.6e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EPE27749.1 - 7.2e-08 32.4 0.1 1.6e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like Homeodomain PF00046.29 EPE27750.1 - 1.4e-19 69.7 3.3 2.7e-19 68.7 3.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EPE27750.1 - 0.0069 16.3 0.5 0.016 15.1 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain MIP-T3_C PF17749.1 EPE27750.1 - 0.067 13.2 2.8 0.12 12.4 2.8 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Pacs-1 PF10254.9 EPE27750.1 - 1 8.2 3.8 1.5 7.7 3.8 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein PhoLip_ATPase_C PF16212.5 EPE27751.1 - 1.1e-70 238.2 21.0 1.1e-70 238.2 21.0 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EPE27751.1 - 1.4e-23 82.4 3.3 3e-22 78.1 0.6 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EPE27751.1 - 1.7e-16 61.2 0.2 3.4e-07 30.8 0.1 3.4 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPE27751.1 - 1.8e-12 47.2 0.0 2e-11 43.8 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EPE27751.1 - 1.3e-10 41.1 0.1 3.5e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EPE27751.1 - 3.9e-05 23.5 0.1 8.6e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EPE27751.1 - 0.017 15.2 0.2 0.48 10.5 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EPE27751.1 - 0.13 12.4 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Aha1_N PF09229.11 EPE27752.1 - 2.7e-40 137.8 1.1 6.6e-40 136.5 0.8 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EPE27752.1 - 7.6e-21 74.6 0.1 1.6e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF1138 PF06592.13 EPE27754.1 - 0.019 15.0 0.2 0.76 9.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1138) DUF2975 PF11188.8 EPE27754.1 - 0.37 10.7 3.3 1.9 8.3 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2975) WD40 PF00400.32 EPE27755.1 - 2.8e-40 135.5 15.1 2e-06 28.4 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EPE27755.1 - 2.3e-11 43.4 0.0 4.7e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE27755.1 - 2.2e-10 40.2 0.1 9.1e-10 38.2 0.0 2.1 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 EPE27755.1 - 1e-08 35.3 0.7 1.5 9.2 0.0 5.7 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPE27755.1 - 9.2e-06 24.6 6.1 2.3 6.7 0.0 5.3 3 1 2 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EPE27755.1 - 0.0019 17.8 0.6 4.1 6.9 0.1 3.0 2 1 1 3 3 3 3 PQQ-like domain F-box_4 PF15966.5 EPE27755.1 - 0.002 18.0 0.0 0.0044 16.9 0.0 1.6 1 0 0 1 1 1 1 F-box CPSF_A PF03178.15 EPE27755.1 - 0.017 14.4 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 CPSF A subunit region WD40_like PF17005.5 EPE27755.1 - 0.08 12.3 0.0 11 5.3 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain DUF2267 PF10025.9 EPE27755.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) PRANC PF09372.10 EPE27755.1 - 0.2 12.0 0.0 0.43 10.9 0.0 1.5 1 0 0 1 1 1 0 PRANC domain HORMA PF02301.18 EPE27756.1 - 4.4e-21 75.4 0.0 7.6e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 HORMA domain UPF1_Zn_bind PF09416.10 EPE27756.1 - 0.011 15.7 0.8 0.02 14.8 0.8 1.4 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) PHD PF00628.29 EPE27756.1 - 0.84 9.6 11.3 1.4 8.9 10.7 1.7 2 0 0 2 2 2 0 PHD-finger Nuc_sug_transp PF04142.15 EPE27758.1 - 4.1e-95 318.6 12.8 6.3e-95 318.0 12.8 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EPE27758.1 - 3.4e-05 24.0 21.8 0.019 15.2 1.3 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EPE27758.1 - 0.0023 17.2 14.0 0.064 12.5 13.9 2.5 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.16 EPE27758.1 - 0.0029 17.0 13.6 0.017 14.5 6.8 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family DMT_6 PF04342.12 EPE27758.1 - 0.87 9.8 10.4 3.5 7.9 0.3 3.1 3 0 0 3 3 3 0 Putative member of DMT superfamily (DUF486) Sec63 PF02889.16 EPE27759.1 - 3.3e-29 101.8 0.0 5.2e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EPE27759.1 - 1.1e-24 87.2 0.1 3.1e-24 85.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EPE27759.1 - 1e-10 41.9 0.0 2.8e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EPE27759.1 - 1.7e-08 34.7 0.0 1e-07 32.3 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 EPE27759.1 - 2.7e-05 24.7 0.0 6.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_19 PF13245.6 EPE27759.1 - 3.1e-05 24.4 0.1 0.00031 21.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EPE27759.1 - 0.001 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EPE27759.1 - 0.029 13.9 1.5 0.18 11.3 0.0 2.5 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EPE27759.1 - 0.03 14.6 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Cdd1 PF11731.8 EPE27759.1 - 0.041 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus Helicase_RecD PF05127.14 EPE27759.1 - 0.053 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Helicase DNA_pol_lambd_f PF10391.9 EPE27759.1 - 0.18 11.7 0.0 0.54 10.1 0.0 1.8 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda DUF1129 PF06570.11 EPE27760.1 - 0.53 9.7 3.9 1.3 8.5 3.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Complex1_51K PF01512.17 EPE27761.1 - 5.1e-47 159.6 0.0 7.9e-47 158.9 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EPE27761.1 - 3.1e-29 100.9 0.2 3.1e-29 100.9 0.2 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EPE27761.1 - 1.2e-08 34.6 0.0 2.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 SLBB domain Hexapep PF00132.24 EPE27762.1 - 1.3e-09 37.3 15.2 1.6e-05 24.4 1.1 4.0 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 EPE27762.1 - 0.006 14.8 0.2 0.0069 14.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EPE27762.1 - 0.008 15.9 16.7 0.061 13.1 0.1 4.1 2 2 2 4 4 4 2 Hexapeptide repeat of succinyl-transferase TPR_MLP1_2 PF07926.12 EPE27763.1 - 2e-40 137.9 25.5 2e-40 137.9 25.5 19.2 7 4 9 18 18 18 5 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 EPE27763.1 - 0.0014 18.6 16.9 0.0014 18.6 16.9 17.5 5 4 9 16 16 16 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TFA2_Winged_2 PF18121.1 EPE27764.1 - 4.4e-25 87.1 0.2 1.1e-24 85.9 0.1 1.7 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EPE27764.1 - 3.6e-17 62.4 0.1 1.2e-16 60.8 0.0 1.9 2 1 0 2 2 2 1 TFIIE beta subunit core domain DSBA PF01323.20 EPE27765.1 - 5.4e-36 124.2 0.0 6.1e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EPE27765.1 - 6.1e-05 23.2 0.0 0.0014 18.8 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 EPE27765.1 - 0.011 15.8 0.1 0.62 10.1 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain zf-C2H2 PF00096.26 EPE27767.1 - 6.2e-22 76.8 26.5 3.6e-05 24.0 1.7 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPE27767.1 - 2.7e-18 65.5 31.9 1.7e-06 28.2 1.2 5.9 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPE27767.1 - 3.5e-13 49.2 24.1 0.0041 17.8 1.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE27767.1 - 6.2e-06 26.4 0.1 10 6.5 0.0 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 EPE27767.1 - 0.0064 16.1 1.0 1.1 8.8 0.2 3.0 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-met PF12874.7 EPE27767.1 - 0.016 15.5 11.5 7.3 7.1 0.4 4.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EPE27767.1 - 0.018 14.8 12.1 0.02 14.7 0.8 3.4 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_aberr PF17017.5 EPE27767.1 - 0.053 13.7 1.6 3.4 7.8 0.1 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 EPE27767.1 - 0.17 12.6 2.8 14 6.4 0.5 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 EPE27767.1 - 0.27 11.2 7.0 4.6 7.3 0.5 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-TRAF PF02176.18 EPE27767.1 - 0.81 10.4 10.1 1.1 9.9 0.9 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger zf-CRD PF17979.1 EPE27767.1 - 1.4 9.0 6.4 9.4 6.3 1.6 2.2 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions IBR PF01485.21 EPE27767.1 - 1.7 8.9 8.6 14 6.0 0.2 3.1 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain Zn-ribbon_8 PF09723.10 EPE27767.1 - 2.1 8.5 9.0 18 5.5 1.5 3.2 1 1 3 4 4 4 0 Zinc ribbon domain zf-LYAR PF08790.11 EPE27767.1 - 8.4 6.4 5.5 6.2 6.8 0.1 3.1 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf_C2H2_13 PF18508.1 EPE27767.1 - 8.9 6.0 6.2 1.7 8.3 0.1 2.6 3 0 0 3 3 3 0 Zinc finger domain DHBP_synthase PF00926.19 EPE27768.1 - 5.6e-80 267.4 0.1 6.6e-80 267.2 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Methyltransf_23 PF13489.6 EPE27769.1 - 2.8e-18 66.3 0.0 3.7e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE27769.1 - 3e-17 63.0 0.0 4.7e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE27769.1 - 5.1e-14 52.3 0.0 7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE27769.1 - 7.7e-14 52.2 0.0 1.4e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE27769.1 - 4.9e-13 49.7 0.0 7.6e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EPE27769.1 - 5.6e-08 32.5 0.0 7.9e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EPE27769.1 - 1.8e-05 24.1 0.0 2.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EPE27769.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EPE27769.1 - 0.029 14.3 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 EPE27769.1 - 0.045 14.8 0.0 0.1 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Telomere_Sde2_2 PF13297.6 EPE27769.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Telomere stability C-terminal BBP1_N PF15271.6 EPE27770.1 - 0.21 12.4 1.9 2.6 8.8 0.5 2.3 2 0 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein Peptidase_S10 PF00450.22 EPE27771.1 - 4.9e-75 253.5 0.0 1e-74 252.5 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase 7TMR-HDED PF07697.11 EPE27773.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.4 1 1 0 1 1 1 0 7TM-HD extracellular UBD PF16455.5 EPE27774.1 - 3.2e-22 78.7 0.0 5.1e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 EPE27774.1 - 0.00065 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EPE27774.1 - 0.0023 17.7 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EPE27774.1 - 0.0097 16.0 0.0 0.021 14.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like 4HBT PF03061.22 EPE27775.1 - 8.7e-05 22.8 0.0 0.0001 22.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 EPE27775.1 - 0.38 10.0 4.0 0.62 9.3 4.2 1.5 1 1 1 2 2 2 0 Acyl-ACP thioesterase MFS_1 PF07690.16 EPE27776.1 - 9.2e-39 133.3 22.9 9.2e-39 133.3 22.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Cu-oxidase_3 PF07732.15 EPE27778.1 - 1e-39 135.2 1.0 1e-39 135.2 1.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EPE27778.1 - 1.2e-38 132.0 0.9 1.2e-38 132.0 0.9 3.1 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EPE27778.1 - 1.4e-36 126.0 4.4 5.3e-36 124.1 0.8 2.8 3 1 0 3 3 3 1 Multicopper oxidase TMEM234 PF10639.9 EPE27779.1 - 3.7e-35 120.5 1.1 6.9e-35 119.6 1.1 1.4 1 1 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 EPE27779.1 - 0.00024 21.3 8.2 0.0021 18.3 8.2 2.0 1 1 0 1 1 1 1 EamA-like transporter family CaATP_NAI PF12515.8 EPE27779.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain DUF2011 PF09428.10 EPE27780.1 - 0.072 13.3 0.0 2 8.7 0.0 2.5 2 2 0 2 2 2 0 Fungal protein of unknown function (DUF2011) Proteasome PF00227.26 EPE27781.1 - 3.4e-47 160.4 0.0 4.7e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EPE27781.1 - 2.1e-12 46.5 0.6 3.9e-12 45.6 0.6 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2373 PF10180.9 EPE27782.1 - 1.1e-24 86.0 0.1 2.4e-24 85.0 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) SpoVR PF04293.13 EPE27782.1 - 0.23 10.1 2.6 0.39 9.4 2.6 1.3 1 0 0 1 1 1 0 SpoVR like protein DUF572 PF04502.13 EPE27782.1 - 0.25 10.9 27.7 0.12 12.0 5.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) Transferase PF02458.15 EPE27782.1 - 1.8 7.1 8.2 1.3 7.6 5.6 1.8 2 0 0 2 2 2 0 Transferase family L_HMGIC_fpl PF10242.9 EPE27783.1 - 0.0017 18.6 5.3 0.0043 17.3 5.3 1.7 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Pox_A14 PF05767.12 EPE27783.1 - 0.089 13.0 2.8 0.34 11.1 1.6 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Glyco_hydro_65m PF03632.15 EPE27784.1 - 5.1e-28 98.0 8.3 3.9e-23 81.9 3.3 2.5 2 1 1 3 3 3 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 EPE27784.1 - 3.2e-26 92.4 0.1 5.9e-25 88.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain F5_F8_type_C PF00754.25 EPE27784.1 - 0.0003 20.9 0.6 0.0038 17.3 0.1 3.0 2 1 0 2 2 2 1 F5/8 type C domain Dabb PF07876.12 EPE27785.1 - 1.9e-20 73.3 0.3 2.7e-20 72.8 0.3 1.3 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ArfGap PF01412.18 EPE27786.1 - 4.5e-30 104.1 0.1 1.7e-27 95.8 0.0 4.0 5 0 0 5 5 5 2 Putative GTPase activating protein for Arf Cupin_5 PF06172.11 EPE27787.1 - 1.7e-50 170.9 0.0 2e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) C2 PF00168.30 EPE27788.1 - 4.4e-16 59.1 0.0 7.9e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain HA2 PF04408.23 EPE27789.1 - 2.3e-24 85.7 0.5 6e-24 84.4 0.1 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EPE27789.1 - 1.7e-18 66.8 0.0 4e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.23 EPE27789.1 - 6.1e-11 42.5 0.1 1.4e-10 41.4 0.1 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.31 EPE27789.1 - 5.1e-10 39.7 0.0 1.4e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPE27789.1 - 3.2e-06 27.0 0.5 8.6e-06 25.6 0.5 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EPE27789.1 - 7.4e-05 23.0 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPE27789.1 - 0.00053 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EPE27789.1 - 0.0045 16.1 0.0 0.0099 15.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EPE27789.1 - 0.016 15.6 0.1 0.033 14.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EPE27789.1 - 0.054 14.0 2.1 1.1 9.7 0.1 3.3 3 1 1 4 4 3 0 ABC transporter AAA_14 PF13173.6 EPE27789.1 - 0.056 13.5 0.6 0.77 9.8 0.6 2.3 1 1 0 1 1 1 0 AAA domain Herpes_ori_bp PF02399.15 EPE27789.1 - 0.077 11.0 0.0 0.11 10.5 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein PhoH PF02562.16 EPE27789.1 - 0.084 12.3 0.1 0.23 10.9 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 EPE27789.1 - 0.11 12.9 0.0 0.36 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EPE27789.1 - 0.13 12.8 0.1 0.4 11.2 0.1 1.8 1 0 0 1 1 1 0 AAA domain zf-RING_2 PF13639.6 EPE27790.1 - 3.7e-07 30.4 11.5 7.1e-07 29.5 11.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EPE27790.1 - 6.4e-05 22.7 8.5 0.00011 22.0 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPE27790.1 - 0.00011 22.5 8.1 0.00028 21.1 8.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EPE27790.1 - 0.00017 21.4 10.3 0.00028 20.7 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE27790.1 - 0.0013 18.6 12.6 0.0022 17.8 12.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE27790.1 - 0.54 10.2 7.7 1 9.3 7.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Abhydrolase_6 PF12697.7 EPE27791.1 - 4.5e-06 27.4 0.2 6.6e-06 26.9 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE27791.1 - 2.6e-05 23.6 0.1 3.9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EPE27791.1 - 0.022 14.2 0.1 2.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Methyltransf_23 PF13489.6 EPE27792.1 - 2.2e-20 73.2 0.0 3.4e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE27792.1 - 2.9e-08 34.3 0.0 6.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE27792.1 - 4.2e-08 33.8 0.0 1.8e-07 31.8 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE27792.1 - 2.1e-06 27.6 0.0 1.5e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE27792.1 - 2.9e-06 27.8 0.0 7.5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EPE27792.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase DUF938 PF06080.12 EPE27792.1 - 0.027 14.2 0.0 0.065 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 EPE27792.1 - 0.044 13.1 0.0 0.1 11.8 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain MTS PF05175.14 EPE27792.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Pyridoxal_deC PF00282.19 EPE27793.1 - 1e-30 106.7 0.0 1.9e-30 105.8 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 EPE27793.1 - 0.00055 19.2 0.0 0.00083 18.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EPE27793.1 - 0.0025 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DUF2462 PF09495.10 EPE27794.1 - 3.6e-23 82.1 8.0 3.6e-23 82.1 8.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) Calc_CGRP_IAPP PF00214.19 EPE27795.1 - 0.081 13.3 0.7 0.29 11.5 0.7 2.0 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family Arginase PF00491.21 EPE27796.1 - 7.9e-91 304.4 0.0 1e-90 304.0 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EPE27796.1 - 0.08 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Shisa PF13908.6 EPE27797.1 - 0.011 16.0 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator CYYR1 PF10873.8 EPE27797.1 - 1.4 9.4 6.6 3.1 8.3 6.6 1.5 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Amino_oxidase PF01593.24 EPE27798.1 - 3.6e-57 194.6 0.0 4.8e-56 191.0 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPE27798.1 - 3.3e-07 30.5 0.0 7.6e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 EPE27798.1 - 0.0083 16.2 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EPE27798.1 - 0.037 13.3 0.1 0.3 10.3 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 EPE27798.1 - 0.13 12.8 0.4 0.9 10.1 0.2 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPE27798.1 - 0.13 11.5 0.0 0.33 10.2 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EPE27798.1 - 0.6 9.4 2.7 1.6 8.0 2.5 1.6 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain CDH-cyt PF16010.5 EPE27800.1 - 7e-24 84.5 0.6 1.2e-23 83.8 0.6 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EPE27800.1 - 8e-10 39.0 10.3 1.4e-09 38.2 10.3 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 EPE27800.1 - 3.3e-08 33.2 2.1 9.9e-08 31.7 2.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF4079 PF13301.6 EPE27800.1 - 0.011 15.9 7.4 0.24 11.5 7.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF373 PF04123.13 EPE27800.1 - 0.64 9.4 5.5 1.1 8.7 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) RseC_MucC PF04246.12 EPE27800.1 - 5.1 7.1 10.9 0.13 12.2 0.7 3.2 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC GFO_IDH_MocA PF01408.22 EPE27801.1 - 3.9e-16 60.0 0.0 9.9e-16 58.7 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EPE27801.1 - 2.8e-06 27.3 0.0 4.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ComA PF02679.15 EPE27801.1 - 0.05 13.1 0.1 0.12 11.8 0.1 1.6 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) PI-PLC-C1 PF16670.5 EPE27802.1 - 0.077 12.1 0.0 2.3 7.2 0.0 2.3 1 1 1 2 2 2 0 Phosphoinositide phospholipase C, Ca2+-dependent Sigma54_AID PF00309.20 EPE27802.1 - 0.19 11.6 0.1 0.19 11.6 0.1 1.7 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) Zn_clus PF00172.18 EPE27803.1 - 1.1e-09 38.2 10.7 2e-09 37.4 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1515 PF07439.11 EPE27803.1 - 0.19 11.8 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) UAF_Rrn10 PF05234.11 EPE27805.1 - 0.0021 18.3 0.1 0.0042 17.3 0.1 1.5 1 1 0 1 1 1 1 UAF complex subunit Rrn10 TDRP PF15683.5 EPE27805.1 - 0.026 14.5 0.0 0.044 13.8 0.0 1.3 1 0 0 1 1 1 0 Testis development-related protein Cyclase PF04199.13 EPE27806.1 - 3.3e-09 37.1 0.0 5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase DUF2716 PF10898.8 EPE27806.1 - 0.07 13.5 0.7 2.3 8.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) MFS_1 PF07690.16 EPE27807.1 - 1.1e-36 126.6 32.5 1.1e-36 126.6 32.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EPE27807.1 - 0.0058 15.0 6.5 0.021 13.1 2.9 2.5 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF3493 PF11998.8 EPE27807.1 - 0.059 13.5 0.4 3.8 7.7 0.2 2.7 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 WD40 PF00400.32 EPE27808.1 - 6.8e-13 48.9 8.6 5.3e-06 27.1 0.4 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE27808.1 - 7.6e-08 32.6 0.0 0.023 15.0 0.0 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Clr5 PF14420.6 EPE27809.1 - 2.3e-06 27.7 0.0 5.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Clr5 domain HD PF01966.22 EPE27809.1 - 8.6e-05 22.8 0.1 0.00034 20.8 0.1 2.1 1 1 0 1 1 1 1 HD domain HTH_32 PF13565.6 EPE27809.1 - 0.044 14.4 2.9 0.091 13.4 0.0 2.8 2 1 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 EPE27809.1 - 0.045 14.0 0.1 0.18 12.1 0.1 2.0 1 0 0 1 1 1 0 Transposase eRF1_2 PF03464.15 EPE27809.1 - 0.079 13.3 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 eRF1 domain 2 Arg_repressor PF01316.21 EPE27809.1 - 0.12 12.2 0.0 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain HTH_12 PF08461.10 EPE27809.1 - 0.21 11.6 0.9 4.8 7.2 0.2 2.4 1 1 1 2 2 2 0 Ribonuclease R winged-helix domain F-box PF00646.33 EPE27810.1 - 3.6e-06 26.7 0.1 7.4e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPE27810.1 - 6.8e-06 25.9 0.2 1.8e-05 24.5 0.1 1.7 1 1 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EPE27810.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 F-box CFEM PF05730.11 EPE27812.1 - 8.5e-11 41.8 9.8 1.6e-10 40.9 9.8 1.5 1 0 0 1 1 1 1 CFEM domain TH1 PF04858.13 EPE27812.1 - 0.039 12.6 0.8 0.045 12.4 0.8 1.1 1 0 0 1 1 1 0 TH1 protein DUF5521 PF17659.1 EPE27812.1 - 2.9 5.6 4.8 3.6 5.3 4.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) FSA_C PF10479.9 EPE27812.1 - 4.1 5.4 17.0 4.9 5.2 17.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus 4HBT_2 PF13279.6 EPE27813.1 - 6.8e-07 29.8 0.0 1.1e-06 29.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF2530 PF10745.9 EPE27814.1 - 0.0012 19.0 0.5 0.0012 19.0 0.5 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2530) Ammonium_transp PF00909.21 EPE27815.1 - 1e-95 320.8 23.0 5.3e-95 318.4 23.0 1.8 1 1 0 1 1 1 1 Ammonium Transporter Family G_path_suppress PF15991.5 EPE27816.1 - 8.2 6.5 7.8 10 6.2 7.8 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor Cellulase PF00150.18 EPE27817.1 - 3.3e-19 69.4 3.8 4.2e-19 69.1 3.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EPE27817.1 - 9.8e-07 28.2 0.0 2e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 EPE27817.1 - 2.5e-05 24.1 0.5 3.7e-05 23.5 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.15 EPE27817.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 Beta-galactosidase Pkinase PF00069.25 EPE27819.1 - 6.1e-45 153.6 0.0 5.8e-43 147.2 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE27819.1 - 4.8e-25 88.3 0.0 3e-24 85.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Vac7 PF12751.7 EPE27820.1 - 2.2e-141 471.7 17.2 9.4e-126 420.3 3.0 2.9 3 1 0 3 3 3 2 Vacuolar segregation subunit 7 PXA PF02194.15 EPE27821.1 - 3.4e-35 121.7 1.3 3.9e-35 121.5 0.1 1.8 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 EPE27821.1 - 3.4e-23 82.3 0.1 3.4e-23 82.3 0.1 2.1 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 EPE27821.1 - 1.4e-09 38.0 0.0 2.3e-07 30.8 0.0 2.8 2 0 0 2 2 2 1 PX domain Serglycin PF04360.12 EPE27821.1 - 0.0063 16.5 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Serglycin PC4 PF02229.16 EPE27822.1 - 2.2e-21 75.3 0.6 1.2e-20 72.9 0.1 2.2 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) Hydantoinase_B PF02538.14 EPE27823.1 - 5.5e-220 731.1 0.1 7.3e-220 730.7 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EPE27823.1 - 8.2e-100 333.8 0.9 1.6e-99 332.9 0.9 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EPE27823.1 - 2.1e-60 203.5 0.7 9e-59 198.1 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Ank_2 PF12796.7 EPE27824.1 - 0.016 15.8 0.0 0.036 14.7 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) zinc_ribbon_10 PF10058.9 EPE27824.1 - 0.34 10.7 2.9 0.69 9.7 2.9 1.5 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-RING_2 PF13639.6 EPE27824.1 - 0.5 10.8 8.1 0.062 13.6 3.4 1.9 2 0 0 2 2 2 0 Ring finger domain 4HBT PF03061.22 EPE27825.1 - 6.1e-13 48.9 0.3 1.2e-12 48.0 0.3 1.5 1 1 0 1 1 1 1 Thioesterase superfamily CH PF00307.31 EPE27826.1 - 3.5e-68 226.7 0.0 7.4e-17 61.5 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 EPE27826.1 - 2.5e-06 27.8 0.7 2.7e-05 24.5 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EPE27826.1 - 0.00082 18.8 1.3 0.19 11.3 0.3 3.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 EPE27826.1 - 0.00083 19.1 0.5 0.048 13.6 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EPE27826.1 - 0.34 10.5 2.3 0.62 9.7 0.3 2.4 2 0 0 2 2 2 0 EF hand HCMVantigenic_N PF12154.8 EPE27826.1 - 2.9 8.1 6.7 7.3 6.8 0.4 2.4 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV MBOAT PF03062.19 EPE27827.1 - 1.2e-38 133.3 11.5 1.2e-38 133.3 11.5 2.0 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EPE27827.1 - 0.00061 20.0 0.5 0.0015 18.7 0.5 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MIT PF04212.18 EPE27829.1 - 2.3e-15 56.4 0.8 4.7e-15 55.4 0.8 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DDHD PF02862.17 EPE27830.1 - 4.2e-61 207.0 0.0 4e-60 203.7 0.0 2.3 2 0 0 2 2 2 1 DDHD domain AAR2 PF05282.11 EPE27830.1 - 0.0002 20.9 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 AAR2 protein RRM_1 PF00076.22 EPE27831.1 - 2.3e-12 46.6 0.0 3.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EPE27831.1 - 0.00018 21.4 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.27 EPE27832.1 - 4.7e-72 238.0 4.3 4.9e-24 84.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EPE27832.1 - 0.0002 20.6 0.2 0.0047 16.1 0.0 2.8 1 1 2 4 4 4 1 Gammaproteobacterial serine protease PT-VENN PF04829.13 EPE27832.1 - 0.44 10.7 4.6 9.5 6.4 0.0 3.2 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Ribosomal_L18 PF17135.4 EPE27833.1 - 1.8e-94 314.4 3.5 2e-94 314.3 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EPE27833.1 - 0.0011 19.7 1.6 0.0011 19.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A FtsJ PF01728.19 EPE27834.1 - 4.6e-56 189.7 0.0 5.7e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 EPE27834.1 - 0.00032 20.6 0.0 0.0018 18.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE27834.1 - 0.0045 16.8 0.0 0.043 13.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain LPP PF04728.13 EPE27835.1 - 0.01 16.2 0.5 0.01 16.2 0.5 5.2 5 1 1 6 6 6 0 Lipoprotein leucine-zipper DUF4279 PF14106.6 EPE27835.1 - 3.2 8.0 5.9 12 6.2 1.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4279) OST3_OST6 PF04756.13 EPE27836.1 - 2.1e-93 312.9 0.0 2.5e-93 312.6 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 EPE27836.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin HXXEE PF13787.6 EPE27836.1 - 0.033 15.0 0.7 0.068 14.0 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function with HXXEE motif NmrA PF05368.13 EPE27837.1 - 3.7e-18 65.9 0.0 6.3e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE27837.1 - 1.9e-13 50.7 0.1 4.2e-13 49.6 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding HIT PF01230.23 EPE27838.1 - 4e-24 85.2 0.0 6.2e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EPE27838.1 - 8.5e-05 23.0 0.0 0.00013 22.4 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding WSC PF01822.19 EPE27839.1 - 9.1e-61 202.0 62.7 2.5e-17 62.8 8.4 5.2 5 0 0 5 5 5 4 WSC domain PQQ_3 PF13570.6 EPE27839.1 - 0.00014 22.3 1.3 0.84 10.2 0.0 4.4 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 EPE27839.1 - 0.031 14.2 0.2 0.27 11.2 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat Prok-RING_1 PF14446.6 EPE27839.1 - 0.058 13.3 0.9 0.23 11.4 0.9 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Cys_Met_Meta_PP PF01053.20 EPE27840.1 - 6.6e-30 103.9 0.0 9.6e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EPE27840.1 - 5.6e-05 22.5 0.0 0.00018 20.8 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II AMP-binding PF00501.28 EPE27841.1 - 7.5e-72 242.2 0.0 1e-71 241.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EPE27841.1 - 2.8e-40 138.1 0.0 5.4e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EPE27841.1 - 2e-06 27.5 0.0 3.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EPE27841.1 - 1.9e-05 24.9 0.5 5.3e-05 23.5 0.1 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EPE27841.1 - 0.00059 18.9 0.2 0.0028 16.7 0.2 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EPE27841.1 - 0.0033 18.4 0.0 0.0099 16.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FrhB_FdhB_N PF04422.13 EPE27841.1 - 0.0061 16.7 0.3 0.036 14.2 0.0 2.5 2 0 0 2 2 2 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Semialdhyde_dh PF01118.24 EPE27841.1 - 0.029 14.8 0.0 0.08 13.4 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 EPE27841.1 - 0.064 13.2 0.2 6.4 6.7 0.0 2.7 2 0 0 2 2 2 0 KR domain FAD_binding_4 PF01565.23 EPE27842.1 - 1.4e-22 79.9 2.3 1.7e-22 79.6 1.5 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EPE27842.1 - 1.4e-11 44.3 0.2 4.3e-11 42.7 0.1 1.9 2 0 0 2 2 2 1 Berberine and berberine like MFS_1 PF07690.16 EPE27843.1 - 4.8e-25 88.2 7.4 5.4e-25 88.1 7.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EPE27843.1 - 1.1e-05 24.9 2.2 1.2e-05 24.8 2.2 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EPE27843.1 - 1.8e-05 23.2 0.7 3.5e-05 22.3 0.4 1.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EPE27843.1 - 2.4e-05 23.4 3.3 3e-05 23.1 3.3 1.0 1 0 0 1 1 1 1 MFS_1 like family PUCC PF03209.15 EPE27843.1 - 2.7e-05 23.4 2.1 3e-05 23.2 2.1 1.2 1 0 0 1 1 1 1 PUCC protein MFS_5 PF05631.14 EPE27843.1 - 0.00038 19.5 0.1 0.00046 19.2 0.1 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Sugar_tr PF00083.24 EPE27843.1 - 0.00064 18.7 2.3 0.0008 18.4 2.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 EPE27843.1 - 0.00065 18.2 4.8 0.00081 17.9 4.8 1.0 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 EPE27844.1 - 2.5e-09 36.6 20.8 4.4e-09 35.7 20.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3114 PF11311.8 EPE27845.1 - 0.041 13.4 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) SSXRD PF09514.10 EPE27847.1 - 0.55 9.9 1.8 0.59 9.8 0.3 1.8 2 0 0 2 2 2 0 SSXRD motif VID27 PF08553.10 EPE27848.1 - 6.7e-198 656.9 0.1 9e-198 656.5 0.1 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EPE27848.1 - 1e-75 253.3 1.9 1e-75 253.3 1.9 2.9 2 1 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 EPE27848.1 - 4.4e-44 149.2 1.7 9.7e-44 148.1 0.8 2.0 2 0 0 2 2 2 1 VID27 PH-like domain UPF0149 PF03695.13 EPE27848.1 - 0.3 11.4 8.1 0.41 10.9 3.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) Mg_trans_NIPA PF05653.14 EPE27850.1 - 3.5e-88 295.5 16.8 2.2e-86 289.6 16.8 2.0 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EPE27850.1 - 7.6e-05 22.9 7.2 7.6e-05 22.9 7.2 4.4 3 1 0 3 3 3 2 EamA-like transporter family DNA_methylase PF00145.17 EPE27851.1 - 2.7e-33 115.7 0.0 9.1e-33 114.0 0.0 1.9 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 EPE27851.1 - 9.5e-07 28.7 0.3 0.013 15.3 0.1 2.4 2 0 0 2 2 2 2 BAH domain DUF3602 PF12223.8 EPE27852.1 - 0.00051 20.6 0.3 0.00051 20.6 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3602) TAFII28 PF04719.14 EPE27853.1 - 0.017 15.2 0.1 0.13 12.3 0.0 2.4 2 0 0 2 2 2 0 hTAFII28-like protein conserved region WD40 PF00400.32 EPE27854.1 - 1.4e-10 41.6 8.7 0.079 13.9 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE27854.1 - 0.0092 16.3 0.0 8.3 6.8 0.0 3.7 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain GRAM PF02893.20 EPE27855.1 - 4e-32 110.5 2.2 3.4e-19 68.8 0.0 3.5 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 EPE27855.1 - 8.5e-29 100.4 0.0 2.3e-28 99.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 EPE27855.1 - 7.5e-14 52.1 0.0 4.1e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 EPE27855.1 - 1.9e-05 25.1 0.4 8.3e-05 23.0 0.4 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EPE27855.1 - 0.00014 22.1 0.0 0.00043 20.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.18 EPE27855.1 - 0.00069 18.5 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_2 PF08458.10 EPE27855.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region NIF PF03031.18 EPE27856.1 - 2e-27 95.9 0.0 4.9e-27 94.6 0.0 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 EPE27856.1 - 2.1e-08 34.4 0.2 1.9e-07 31.3 0.0 2.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EPE27856.1 - 2.7e-05 24.0 0.1 5.7e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 EPE27856.1 - 0.027 14.9 0.0 0.16 12.4 0.0 2.2 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EPE27856.1 - 0.088 13.1 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 EPE27856.1 - 0.097 12.6 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 EPE27856.1 - 0.11 12.6 0.2 0.38 10.8 0.2 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain GRIM-19 PF06212.12 EPE27857.1 - 6.4e-22 77.9 0.0 1.3e-21 76.9 0.0 1.5 1 1 0 1 1 1 1 GRIM-19 protein Sigma70_r1_2 PF00140.20 EPE27857.1 - 0.015 15.3 0.3 0.034 14.2 0.1 1.7 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 adh_short_C2 PF13561.6 EPE27858.1 - 4e-37 128.0 0.0 6.2e-37 127.4 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE27858.1 - 7.8e-27 94.0 0.0 9.2e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE27858.1 - 9.3e-08 32.2 0.0 1.3e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 KR domain ADH_N PF08240.12 EPE27859.1 - 5.2e-29 100.3 0.2 5.2e-29 100.3 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE27859.1 - 1.9e-20 73.1 0.4 4.4e-20 72.0 0.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EPE27859.1 - 4e-07 29.8 1.6 2.2e-06 27.3 1.6 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EPE27859.1 - 2.1e-05 23.9 1.5 3.9e-05 23.0 1.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EPE27859.1 - 0.002 17.7 0.2 0.0033 17.0 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 EPE27859.1 - 0.0053 17.8 0.3 0.015 16.4 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.14 EPE27859.1 - 0.023 14.0 0.6 0.096 11.9 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PALP PF00291.25 EPE27859.1 - 0.059 12.8 1.1 4.4 6.6 2.9 2.1 1 1 1 2 2 2 0 Pyridoxal-phosphate dependent enzyme HI0933_like PF03486.14 EPE27859.1 - 0.072 11.8 0.4 0.1 11.3 0.4 1.1 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 EPE27859.1 - 0.073 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain STAS_2 PF13466.6 EPE27859.1 - 0.09 13.1 0.0 9.2 6.7 0.0 2.3 2 0 0 2 2 2 0 STAS domain Methyltransf_25 PF13649.6 EPE27859.1 - 0.11 13.2 0.1 0.2 12.4 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 EPE27859.1 - 0.11 12.3 0.5 0.26 11.2 0.5 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EPE27860.1 - 1.3e-09 37.9 0.1 6.7e-05 22.5 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EPE27860.1 - 4.2e-07 30.4 0.0 1.2e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EPE27860.1 - 1.9e-06 27.9 0.0 3.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPE27860.1 - 1.4e-05 24.8 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EPE27860.1 - 2.2e-05 23.6 0.0 0.07 12.1 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EPE27860.1 - 0.00048 19.4 0.0 0.0018 17.5 0.0 2.0 2 1 0 2 2 2 1 Male sterility protein Acetyltransf_13 PF13880.6 EPE27861.1 - 7.3e-12 45.1 0.0 1.7e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EPE27861.1 - 7.6e-12 44.9 0.5 1.8e-11 43.6 0.5 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 EPE27861.1 - 0.0028 17.9 0.0 0.0056 16.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE27861.1 - 0.033 14.6 0.0 0.066 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPE27861.1 - 0.18 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Fungal_trans_2 PF11951.8 EPE27863.1 - 1.4e-38 132.7 0.0 1.9e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE27863.1 - 7.6e-10 38.8 11.2 1.3e-09 38.0 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1890 PF09001.11 EPE27863.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) AT_hook PF02178.19 EPE27863.1 - 1.5 9.0 10.2 5.4 7.2 10.2 2.0 1 0 0 1 1 1 0 AT hook motif ABC_tran PF00005.27 EPE27864.1 - 2.5e-50 170.6 0.1 4.1e-24 85.6 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EPE27864.1 - 6e-43 146.7 41.6 1.7e-27 96.2 8.8 2.8 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.6 EPE27864.1 - 1.4e-12 48.0 0.9 0.013 15.3 0.1 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPE27864.1 - 9.6e-09 35.0 0.4 0.00048 19.6 0.1 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EPE27864.1 - 1.5e-07 32.0 0.2 0.012 16.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EPE27864.1 - 2.3e-07 30.8 1.7 0.013 15.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EPE27864.1 - 3.7e-07 29.8 3.7 0.0063 16.2 0.7 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EPE27864.1 - 8.4e-07 29.3 0.1 0.031 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EPE27864.1 - 2.1e-06 28.4 2.7 0.0035 17.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EPE27864.1 - 3.4e-06 26.8 0.1 0.078 12.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EPE27864.1 - 5.7e-06 26.2 0.5 0.0069 16.1 0.1 2.7 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 EPE27864.1 - 2.3e-05 24.4 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain T2SSE PF00437.20 EPE27864.1 - 4.2e-05 22.7 0.6 0.067 12.2 0.1 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_28 PF13521.6 EPE27864.1 - 4.4e-05 23.8 0.7 0.14 12.4 0.8 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EPE27864.1 - 0.00035 20.3 0.1 0.86 9.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EPE27864.1 - 0.00041 20.4 0.2 1.5 8.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EPE27864.1 - 0.00047 20.5 1.0 0.13 12.5 0.6 2.7 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EPE27864.1 - 0.00052 19.8 1.4 1.6 8.3 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 EPE27864.1 - 0.00072 19.9 0.1 1.1 9.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase cobW PF02492.19 EPE27864.1 - 0.0011 18.6 2.1 0.57 9.8 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EPE27864.1 - 0.0012 19.2 0.1 4.6 7.7 0.1 3.4 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EPE27864.1 - 0.0013 18.7 0.1 0.21 11.5 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea SbcCD_C PF13558.6 EPE27864.1 - 0.0017 18.6 1.4 3.3 8.0 0.1 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Pox_A32 PF04665.12 EPE27864.1 - 0.002 17.6 1.8 0.62 9.5 0.2 2.3 2 0 0 2 2 2 2 Poxvirus A32 protein ATP_bind_1 PF03029.17 EPE27864.1 - 0.0027 17.5 1.0 0.59 9.9 0.4 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EPE27864.1 - 0.0032 18.0 0.1 3.2 8.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 EPE27864.1 - 0.0035 16.7 2.0 0.31 10.4 0.4 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EPE27864.1 - 0.0071 16.4 3.1 1.3 9.1 0.4 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase PhoH PF02562.16 EPE27864.1 - 0.0089 15.5 0.4 2.6 7.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Cytidylate_kin PF02224.18 EPE27864.1 - 0.01 15.6 0.1 1.8 8.3 0.0 3.1 3 0 0 3 3 3 0 Cytidylate kinase AAA_7 PF12775.7 EPE27864.1 - 0.012 15.1 2.0 2.8 7.4 0.6 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 EPE27864.1 - 0.013 15.7 0.1 8.2 6.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 EPE27864.1 - 0.013 14.6 0.1 2.8 7.0 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit NTPase_1 PF03266.15 EPE27864.1 - 0.033 14.1 0.8 2 8.3 0.3 3.1 4 0 0 4 4 3 0 NTPase AAA_11 PF13086.6 EPE27864.1 - 0.035 13.9 0.2 8 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EPE27864.1 - 0.039 14.2 0.2 8.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PRK PF00485.18 EPE27864.1 - 0.048 13.4 1.2 2.2 8.0 0.4 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Septin PF00735.18 EPE27864.1 - 0.054 12.8 0.6 4.9 6.4 0.1 2.3 2 0 0 2 2 2 0 Septin MobB PF03205.14 EPE27864.1 - 0.058 13.3 0.3 6.5 6.7 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.6 EPE27864.1 - 0.064 13.7 0.1 1.7 9.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EPE27864.1 - 0.067 12.9 0.5 9.7 5.9 0.0 3.6 5 0 0 5 5 4 0 IstB-like ATP binding protein SRP54 PF00448.22 EPE27864.1 - 0.082 12.5 0.6 11 5.6 0.5 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 EPE27864.1 - 0.09 12.8 0.4 3.5 7.6 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 EPE27864.1 - 0.17 11.1 0.1 6.3 5.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 EPE27864.1 - 0.17 11.1 0.0 16 4.6 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain PIF1 PF05970.14 EPE27864.1 - 0.23 10.6 0.3 4.1 6.5 0.1 2.3 2 0 0 2 2 2 0 PIF1-like helicase Zeta_toxin PF06414.12 EPE27864.1 - 0.28 10.4 0.9 4.8 6.4 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin MFS_1 PF07690.16 EPE27865.1 - 4.7e-52 177.1 12.8 4.7e-52 177.1 12.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE27865.1 - 5.1e-07 28.9 7.0 5.1e-07 28.9 7.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EPE27865.1 - 3.8e-05 22.3 4.1 7.4e-05 21.4 4.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 EPE27865.1 - 0.0018 17.3 1.9 0.003 16.5 1.9 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM P5-ATPase PF12409.8 EPE27865.1 - 0.57 10.3 3.0 0.74 9.9 0.2 2.3 2 0 0 2 2 2 0 P5-type ATPase cation transporter OATP PF03137.20 EPE27865.1 - 3.5 5.8 14.2 19 3.4 14.2 2.0 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Syntaxin-18_N PF10496.9 EPE27867.1 - 1.5e-11 44.4 4.3 1.4e-10 41.3 0.1 3.3 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 EPE27867.1 - 0.0018 18.2 0.1 0.0074 16.3 0.0 2.2 2 0 0 2 2 2 1 SNARE domain TipAS PF07739.13 EPE27867.1 - 0.016 15.8 5.0 0.032 14.8 0.2 2.5 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Sec20 PF03908.13 EPE27867.1 - 0.028 14.3 2.7 0.051 13.5 0.2 2.6 2 1 0 2 2 2 0 Sec20 OTU PF02338.19 EPE27867.1 - 1.5 9.3 3.7 5.6 7.5 0.6 2.8 1 1 1 2 2 2 0 OTU-like cysteine protease KIAA1430 PF13879.6 EPE27867.1 - 4.3 8.1 12.8 1.9 9.3 1.1 2.7 2 1 0 2 2 2 0 KIAA1430 homologue Focal_AT PF03623.13 EPE27867.1 - 4.9 7.2 9.5 0.7 9.9 0.2 2.9 3 0 0 3 3 3 0 Focal adhesion targeting region Aminotran_1_2 PF00155.21 EPE27868.1 - 9.3e-84 281.7 0.0 1.1e-83 281.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Chitin_synth_2 PF03142.15 EPE27869.1 - 1.5e-228 759.7 0.0 2e-228 759.3 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 EPE27869.1 - 9.3e-14 51.1 0.5 4e-13 49.1 0.7 1.9 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 EPE27869.1 - 1.4e-13 50.8 0.2 2.6e-08 33.9 0.1 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 EPE27869.1 - 1.4e-12 48.0 2.8 1.4e-12 48.0 2.8 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EPE27869.1 - 3.1e-10 40.3 0.0 1.2e-09 38.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 EPE27869.1 - 2.1e-07 29.6 0.0 6.7e-07 27.9 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) Glycos_transf_2 PF00535.26 EPE27869.1 - 0.00083 19.2 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EPE27869.1 - 0.005 16.3 0.0 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 EPE27870.1 - 4e-248 824.3 1.9 6.4e-248 823.6 1.9 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EPE27870.1 - 4.3e-72 243.4 0.0 1.9e-71 241.3 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 EPE27870.1 - 1.2e-17 63.8 0.1 1.5e-13 50.7 0.0 3.2 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 EPE27870.1 - 5.8e-16 58.2 0.5 2.4e-15 56.2 0.5 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EPE27870.1 - 4.2e-12 46.4 3.4 4.2e-12 46.4 3.4 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EPE27870.1 - 4.3e-12 46.4 0.0 5.6e-11 42.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EPE27870.1 - 1.4e-05 25.0 0.0 0.022 14.6 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_16 PF13191.6 EPE27870.1 - 0.0061 17.0 0.4 0.027 14.8 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 EPE27870.1 - 0.015 14.8 0.1 0.042 13.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region Glyco_transf_21 PF13506.6 EPE27870.1 - 0.063 12.8 0.2 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 21 SRPRB PF09439.10 EPE27870.1 - 0.21 11.0 0.5 2.9 7.3 0.6 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit NIR_SIR PF01077.22 EPE27871.1 - 2.1e-54 183.3 0.1 1.5e-48 164.3 0.1 2.6 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EPE27871.1 - 2.3e-30 104.2 0.0 1.2e-14 53.9 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EPE27871.1 - 7.2e-28 97.6 0.0 1.7e-27 96.4 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 EPE27871.1 - 1.5e-08 34.7 0.1 2.9e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Death PF00531.22 EPE27871.1 - 0.076 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Death domain Kei1 PF08552.11 EPE27872.1 - 1.3e-65 220.9 5.7 1.6e-65 220.6 5.7 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Ras PF00071.22 EPE27873.1 - 7.6e-52 175.2 0.1 9.9e-52 174.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE27873.1 - 6.3e-34 116.8 0.1 1.1e-33 116.0 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE27873.1 - 1.2e-13 50.9 0.2 1.6e-13 50.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EPE27873.1 - 0.00017 21.6 0.1 0.12 12.3 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EPE27873.1 - 0.00051 20.1 0.1 0.00085 19.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EPE27873.1 - 0.00051 19.5 0.0 0.00079 18.9 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EPE27873.1 - 0.0046 16.3 0.1 0.0081 15.5 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EPE27873.1 - 0.016 14.7 0.1 0.13 11.8 0.1 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Nop53 PF07767.11 EPE27874.1 - 3.4e-110 369.2 26.2 4e-110 368.9 26.2 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF346 PF03984.13 EPE27875.1 - 0.00085 19.0 6.3 0.00085 19.0 6.3 6.2 7 0 0 7 7 7 4 Repeat of unknown function (DUF346) Peptidase_C12 PF01088.21 EPE27876.1 - 3.7e-46 157.5 0.0 4.4e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 EMP70 PF02990.16 EPE27877.1 - 9.3e-208 691.1 0.2 1.1e-207 690.8 0.2 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Pex2_Pex12 PF04757.14 EPE27878.1 - 1.5e-49 168.6 0.8 2.1e-49 168.1 0.8 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 EPE27878.1 - 0.00033 20.4 3.2 0.00058 19.7 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPE27878.1 - 0.0011 18.8 2.2 0.0018 18.1 2.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE27878.1 - 0.003 17.9 3.9 0.0049 17.2 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EPE27878.1 - 0.0032 17.5 2.1 0.0056 16.7 2.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EPE27878.1 - 0.012 15.7 2.2 0.022 14.9 2.2 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EPE27878.1 - 0.016 15.0 3.9 0.028 14.3 3.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 EPE27878.1 - 0.34 10.9 2.6 0.59 10.1 2.6 1.3 1 0 0 1 1 1 0 zinc-ribbons Glyco_hydro_16 PF00722.21 EPE27879.1 - 9.6e-44 149.0 2.7 2.1e-43 147.8 2.7 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 T_cell_tran_alt PF15128.6 EPE27879.1 - 0.11 12.3 0.2 0.31 10.9 0.2 1.7 1 0 0 1 1 1 0 T-cell leukemia translocation-altered Mfa1 PF17445.2 EPE27879.1 - 0.18 11.9 6.1 0.081 13.0 1.8 2.8 2 0 0 2 2 2 0 Mating factor A1 ApoM PF11032.8 EPE27880.1 - 0.00038 20.2 0.0 0.00055 19.7 0.0 1.4 1 0 0 1 1 1 1 ApoM domain FeThRed_B PF02943.15 EPE27881.1 - 0.36 10.8 1.9 19 5.3 0.1 2.3 2 0 0 2 2 2 0 Ferredoxin thioredoxin reductase catalytic beta chain CutC PF03932.14 EPE27883.1 - 1.2e-44 152.2 0.0 1.7e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 CutC family DUF4581 PF15167.6 EPE27883.1 - 0.012 15.8 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) BtpA PF03437.15 EPE27883.1 - 0.19 11.1 0.3 0.81 9.1 0.1 2.0 2 0 0 2 2 2 0 BtpA family APH PF01636.23 EPE27885.1 - 3e-16 60.1 0.0 4.1e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE27885.1 - 1.4e-08 34.6 0.0 2.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EPE27885.1 - 0.0043 16.4 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Pyridox_ox_2 PF12900.7 EPE27886.1 - 2e-37 128.3 0.0 3e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ANAPC8 PF04049.13 EPE27887.1 - 6.4e-42 142.9 0.2 9.3e-41 139.2 0.0 2.5 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 EPE27887.1 - 6.2e-19 66.6 12.9 7e-05 22.7 0.0 7.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 EPE27887.1 - 2.7e-15 55.5 11.0 0.00066 19.4 0.0 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EPE27887.1 - 4.8e-12 45.0 22.4 0.11 12.7 0.0 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 EPE27887.1 - 4.5e-11 43.2 6.9 5.6e-06 26.9 1.7 5.5 5 1 1 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE27887.1 - 3.9e-09 36.6 12.4 0.0039 17.4 0.3 5.7 5 1 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EPE27887.1 - 9.6e-09 34.8 0.3 2.5e-06 27.1 0.1 3.0 1 1 1 2 2 2 1 TPR repeat TPR_14 PF13428.6 EPE27887.1 - 1.2e-08 35.0 15.0 0.0058 17.3 0.1 7.3 6 1 3 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 EPE27887.1 - 6.4e-07 29.4 11.0 0.042 14.0 0.3 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EPE27887.1 - 9.8e-07 29.0 18.2 0.22 11.8 0.1 6.7 6 1 1 7 7 7 2 Tetratricopeptide repeat DUF3856 PF12968.7 EPE27887.1 - 6.6e-06 26.2 1.7 0.0057 16.7 0.2 2.8 1 1 1 2 2 2 2 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 EPE27887.1 - 0.0068 16.9 8.5 9.3 6.8 0.0 6.2 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 EPE27887.1 - 0.017 15.5 2.2 9.6 6.8 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Say1_Mug180 PF10340.9 EPE27887.1 - 0.058 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase TPR_10 PF13374.6 EPE27887.1 - 0.42 10.5 8.0 6.3 6.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EPE27887.1 - 0.69 10.1 0.0 0.69 10.1 0.0 5.6 8 0 0 8 8 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 EPE27887.1 - 1.4 8.0 7.6 0.72 9.0 2.2 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat polyprenyl_synt PF00348.17 EPE27888.1 - 3.2e-91 304.9 0.0 4.1e-91 304.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase RNase_H2-Ydr279 PF09468.10 EPE27888.1 - 0.032 14.4 0.8 1.5 9.0 1.4 2.7 2 2 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain CENP-N PF05238.13 EPE27888.1 - 0.18 11.1 1.2 0.28 10.5 1.2 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF3262 PF11660.8 EPE27889.1 - 1.1 9.7 10.5 5.7 7.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) DUF2976 PF11190.8 EPE27889.1 - 1.8 8.4 7.0 1 9.2 1.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) DUF1996 PF09362.10 EPE27891.1 - 6.7e-81 271.7 0.7 8.5e-81 271.4 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Cation_efflux PF01545.21 EPE27892.1 - 1e-22 80.9 8.8 1.2e-22 80.6 8.8 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EPE27892.1 - 2.9e-05 24.1 0.0 8.4e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PRP9_N PF16958.5 EPE27892.1 - 0.05 13.6 0.7 0.091 12.8 0.7 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus TMEM100 PF16311.5 EPE27892.1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 100 Bmp PF02608.14 EPE27893.1 - 0.1 11.5 0.3 0.13 11.2 0.3 1.1 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like CysA_C_terminal PF17850.1 EPE27894.1 - 0.16 12.6 0.0 0.27 11.8 0.0 1.3 1 0 0 1 1 1 0 CysA C-terminal regulatory domain Spherulin4 PF12138.8 EPE27895.1 - 1.2e-60 205.2 0.0 1.4e-60 204.9 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Glyco_hydro_114 PF03537.13 EPE27896.1 - 5.7e-80 268.0 0.0 7e-80 267.7 0.0 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 SEP PF08059.13 EPE27898.1 - 3.2e-24 85.3 0.0 1e-23 83.7 0.0 1.9 2 0 0 2 2 2 1 SEP domain UBA_4 PF14555.6 EPE27898.1 - 1.8e-12 46.9 0.6 2.8e-12 46.2 0.6 1.3 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EPE27898.1 - 2.4e-11 43.7 0.0 3.9e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.13 EPE27898.1 - 0.052 13.2 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 TAP C-terminal domain TOM13 PF08219.11 EPE27899.1 - 1.2e-36 124.5 0.0 1.5e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.20 EPE27900.1 - 2e-16 60.3 2.0 2.8e-16 59.9 2.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF1996 PF09362.10 EPE27901.1 - 1.2e-83 280.7 0.0 1.8e-83 280.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Gtr1_RagA PF04670.12 EPE27902.1 - 2.1e-91 305.4 0.2 2.9e-91 305.0 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EPE27902.1 - 1.7e-08 34.7 0.0 3.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE27902.1 - 1.2e-07 31.4 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPE27902.1 - 3.4e-07 30.3 0.0 6.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EPE27902.1 - 7.4e-07 28.9 0.1 1.3e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 EPE27902.1 - 9.4e-05 22.4 0.2 0.33 10.8 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 EPE27902.1 - 0.00086 18.6 4.2 0.31 10.1 0.6 2.7 2 1 1 3 3 3 2 G-protein alpha subunit ABC_tran PF00005.27 EPE27902.1 - 0.005 17.3 0.6 0.013 16.0 0.6 2.0 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EPE27902.1 - 0.011 15.4 0.2 0.059 13.1 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.13 EPE27902.1 - 0.023 13.9 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) HATPase_c_4 PF13749.6 EPE27902.1 - 0.041 14.0 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal AAA_7 PF12775.7 EPE27902.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region PAS_9 PF13426.7 EPE27903.1 - 2.8e-15 56.4 0.0 2.7e-14 53.3 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EPE27903.1 - 5e-06 26.5 0.0 1.7e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EPE27903.1 - 0.039 14.3 0.0 0.077 13.3 0.0 1.5 1 0 0 1 1 1 0 PAS fold Cutinase PF01083.22 EPE27904.1 - 1.1e-51 175.3 9.4 1.2e-51 175.1 9.4 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EPE27904.1 - 0.00051 19.6 0.3 0.00091 18.8 0.3 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 EPE27904.1 - 0.05 13.5 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Glyco_hydro_61 PF03443.14 EPE27905.1 - 8.8e-53 179.3 0.0 1.4e-52 178.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 EPE27905.1 - 6.6e-08 31.9 50.2 7.7e-08 31.6 47.1 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily Peptidase_M24 PF00557.24 EPE27906.1 - 3.2e-41 141.3 0.2 4.1e-41 141.0 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 SPT6_acidic PF14632.6 EPE27906.1 - 0.071 13.7 2.5 0.16 12.6 2.5 1.5 1 0 0 1 1 1 0 Acidic N-terminal SPT6 HET PF06985.11 EPE27907.1 - 1.3e-23 83.9 0.0 2.3e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Kdo PF06293.14 EPE27908.1 - 4.7e-05 22.8 0.0 8.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EPE27908.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain RNase_H PF00075.24 EPE27909.1 - 9.1e-09 35.6 0.0 1.1e-08 35.4 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EPE27909.1 - 0.02 14.7 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like Fungal_lectin PF07938.12 EPE27910.1 - 1.6e-07 31.0 0.1 2.3e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Fungal fucose-specific lectin Glyco_hydro_47 PF01532.20 EPE27911.1 - 6e-172 572.7 0.0 6.8e-172 572.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 HET PF06985.11 EPE27912.1 - 2.5e-24 86.3 0.0 6.7e-24 84.9 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TAF6_C PF07571.13 EPE27913.1 - 2.4e-29 101.5 0.0 6.2e-29 100.2 0.0 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EPE27913.1 - 3.4e-20 72.0 0.1 7.2e-20 70.9 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EPE27913.1 - 0.048 14.0 0.2 0.077 13.4 0.2 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Ufd2P_core PF10408.9 EPE27913.1 - 0.084 11.5 0.1 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core TFIID-31kDa PF02291.15 EPE27913.1 - 0.13 12.3 0.2 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Thymidylate_kin PF02223.17 EPE27914.1 - 3.7e-32 111.5 0.0 4.5e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase GTP_cyclohydroI PF01227.22 EPE27915.1 - 2e-73 245.6 0.1 2.8e-73 245.2 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EPE27915.1 - 0.0064 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 QueF-like protein DUF3638 PF12340.8 EPE27915.1 - 0.11 11.8 0.1 0.23 10.8 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3638) Macoilin PF09726.9 EPE27915.1 - 0.4 9.2 3.2 0.46 9.0 3.2 1.1 1 0 0 1 1 1 0 Macoilin family TAFII28 PF04719.14 EPE27916.1 - 4.8e-24 84.3 0.0 1.1e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Ysc84 PF04366.12 EPE27917.1 - 3.6e-45 152.8 0.0 5.2e-45 152.3 0.0 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator Glyco_hydro_3_C PF01915.22 EPE27918.1 - 5.8e-43 147.2 0.0 1.1e-42 146.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE27918.1 - 6.8e-34 117.7 0.0 1.1e-33 116.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE27918.1 - 4.6e-21 74.7 0.1 8e-21 73.9 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain NUDIX PF00293.28 EPE27920.1 - 6.9e-09 35.8 0.0 1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 EPE27920.1 - 5.7e-05 23.1 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) ORF6C PF10552.9 EPE27920.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 ORF6C domain F-box PF00646.33 EPE27922.1 - 0.0038 17.1 0.0 0.0038 17.1 0.0 2.4 3 0 0 3 3 3 1 F-box domain DUF3632 PF12311.8 EPE27923.1 - 5.1e-28 98.7 0.1 7.2e-28 98.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) p450 PF00067.22 EPE27925.1 - 4.4e-51 174.1 0.0 5.8e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HeLo PF14479.6 EPE27926.1 - 2.1e-46 158.4 0.1 3.4e-46 157.7 0.1 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation UQ_con PF00179.26 EPE27926.1 - 5.6e-24 84.4 0.0 3e-23 82.0 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin-conjugating enzyme Zn_clus PF00172.18 EPE27926.1 - 0.38 10.9 7.0 1 9.5 7.0 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sdh_cyt PF01127.22 EPE27927.1 - 7.3e-24 84.1 2.5 1e-23 83.7 2.5 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sugar_tr PF00083.24 EPE27928.1 - 1.2e-129 433.1 27.0 1.4e-129 432.9 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE27928.1 - 3.8e-17 62.2 37.7 3.8e-17 62.2 37.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_1 PF00232.18 EPE27929.1 - 2.7e-99 332.6 0.9 3.5e-99 332.3 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 TGT PF01702.18 EPE27930.1 - 7.5e-65 219.4 0.0 9.2e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase HET PF06985.11 EPE27931.1 - 6.3e-26 91.5 0.0 1.2e-25 90.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF5512 PF17631.2 EPE27932.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5512) HET PF06985.11 EPE27933.1 - 4.2e-29 101.8 0.0 1.2e-28 100.4 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Dscam_C PF12355.8 EPE27933.1 - 0.21 12.5 0.4 0.95 10.4 0.1 2.1 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal AAA_28 PF13521.6 EPE27934.1 - 2.7e-27 96.0 0.0 3e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EPE27934.1 - 0.00042 20.4 0.2 0.00059 19.9 0.2 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase dNK PF01712.19 EPE27934.1 - 0.00066 19.6 0.1 0.0011 18.9 0.1 1.6 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_33 PF13671.6 EPE27934.1 - 0.0014 18.8 0.0 0.023 14.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EPE27934.1 - 0.0018 18.1 0.0 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 EPE27934.1 - 0.0067 16.8 0.0 0.0092 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_32 PF13654.6 EPE27934.1 - 0.014 14.3 0.1 0.024 13.5 0.0 1.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 EPE27934.1 - 0.016 15.1 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 SRPRB PF09439.10 EPE27934.1 - 0.023 14.1 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EPE27934.1 - 0.027 14.0 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 EPE27934.1 - 0.031 14.8 0.0 0.058 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EPE27934.1 - 0.035 14.5 0.0 0.059 13.8 0.0 1.6 1 1 0 1 1 1 0 RNA helicase GTP_EFTU PF00009.27 EPE27934.1 - 0.039 13.5 0.0 0.23 10.9 0.0 1.9 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EPE27934.1 - 0.04 13.1 0.0 0.043 13.0 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 EPE27934.1 - 0.041 13.2 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 EPE27934.1 - 0.045 13.5 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EPE27934.1 - 0.062 13.6 0.0 0.099 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 EPE27934.1 - 0.067 13.1 0.1 0.12 12.2 0.1 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 EPE27934.1 - 0.072 13.3 0.0 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 EPE27934.1 - 0.074 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Septin TniB PF05621.11 EPE27934.1 - 0.083 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Dynamin_N PF00350.23 EPE27934.1 - 0.089 12.8 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 Dynamin family AAA_23 PF13476.6 EPE27934.1 - 0.13 12.7 0.1 0.16 12.4 0.1 1.3 1 1 0 1 1 1 0 AAA domain RdRP PF05183.12 EPE27935.1 - 3.7e-120 402.3 0.0 5.5e-120 401.7 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_12 PF13087.6 EPE27935.1 - 1.2e-47 162.2 0.0 3.4e-47 160.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EPE27935.1 - 2.4e-44 152.1 0.6 3.5e-21 76.2 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EPE27935.1 - 1e-13 51.5 0.0 2.9e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPE27935.1 - 1.9e-13 51.0 0.1 1.5e-12 48.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 EPE27935.1 - 5e-06 26.5 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Helicase ResIII PF04851.15 EPE27935.1 - 5.6e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 EPE27935.1 - 3.2e-05 23.8 0.0 0.76 9.5 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EPE27935.1 - 0.0003 20.3 0.0 0.0026 17.2 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 EPE27935.1 - 0.00058 20.1 0.0 0.0031 17.8 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 EPE27935.1 - 0.0011 19.4 0.1 0.012 16.0 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 EPE27935.1 - 0.0017 18.0 0.0 0.013 15.1 0.0 2.2 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 EPE27935.1 - 0.0053 17.2 0.0 0.018 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 EPE27935.1 - 0.0059 16.4 0.1 0.021 14.7 0.0 2.1 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain TsaE PF02367.17 EPE27935.1 - 0.053 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 EPE27935.1 - 0.066 13.0 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase RecJ_OB PF17768.1 EPE27935.1 - 0.1 12.9 0.0 2.2 8.6 0.0 2.7 2 0 0 2 2 2 0 RecJ OB domain RNA_helicase PF00910.22 EPE27935.1 - 0.11 12.8 0.0 0.4 11.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 EPE27935.1 - 0.14 11.0 0.0 0.3 10.0 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ATPase_2 PF01637.18 EPE27935.1 - 0.16 11.8 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EPE27935.1 - 0.19 11.4 0.1 0.78 9.4 0.1 2.1 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EPE27935.1 - 0.28 10.4 2.7 4 6.6 0.1 3.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) HET PF06985.11 EPE27936.1 - 4.4e-28 98.5 0.0 6.7e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SAM_decarbox PF01536.16 EPE27938.1 - 7.9e-134 446.2 0.0 1.4e-133 445.4 0.0 1.4 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase DUF3090 PF11290.8 EPE27938.1 - 0.12 12.2 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) BTB PF00651.31 EPE27939.1 - 0.0084 16.3 0.0 0.05 13.8 0.0 2.1 2 1 1 3 3 3 1 BTB/POZ domain Ank_2 PF12796.7 EPE27940.1 - 1e-10 42.0 0.0 2.9e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE27940.1 - 9.5e-09 35.6 0.0 4.7e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SesA PF17107.5 EPE27940.1 - 2.5e-07 30.9 0.0 5.9e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_3 PF13606.6 EPE27940.1 - 3.4e-07 30.0 0.0 0.0043 17.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EPE27940.1 - 1.4e-05 25.3 0.0 0.0019 18.6 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EPE27940.1 - 2.1e-05 24.7 0.0 0.00012 22.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Helo_like_N PF17111.5 EPE27940.1 - 6.5e-05 22.4 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins BID PF06393.11 EPE27942.1 - 0.15 11.6 4.2 0.3 10.6 4.2 1.4 1 0 0 1 1 1 0 BH3 interacting domain (BID) TT_ORF2 PF02957.15 EPE27942.1 - 1.7 9.6 6.0 8.3 7.4 5.3 2.5 2 0 0 2 2 2 0 TT viral ORF2 ParA PF10609.9 EPE27943.1 - 3.8e-91 304.9 0.2 4.9e-91 304.6 0.2 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EPE27943.1 - 8.9e-10 38.7 0.0 2.7e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EPE27943.1 - 2.3e-06 27.1 0.0 3.7e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 EPE27943.1 - 2.3e-05 24.4 0.1 0.0013 18.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 EPE27943.1 - 7.7e-05 22.0 1.1 0.00014 21.1 0.5 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 EPE27943.1 - 0.0019 17.2 0.2 0.0033 16.5 0.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 EPE27943.1 - 0.0055 16.3 0.2 0.01 15.4 0.2 1.4 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 EPE27943.1 - 0.021 14.3 0.6 0.074 12.5 0.6 1.8 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 EPE27943.1 - 0.058 13.2 1.7 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EPE27943.1 - 0.16 11.9 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 EPE27943.1 - 0.17 11.0 0.2 0.25 10.5 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 EPE27943.1 - 0.23 11.8 0.6 0.55 10.6 0.6 1.6 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EPE27943.1 - 0.39 10.6 3.3 0.25 11.2 1.2 1.6 2 0 0 2 2 2 0 RsgA GTPase AA_permease PF00324.21 EPE27944.1 - 5e-140 467.3 38.7 6.2e-140 467.0 38.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE27944.1 - 1.2e-41 143.0 40.7 1.5e-41 142.6 40.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF758 PF05527.11 EPE27945.1 - 0.057 13.4 0.1 0.079 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF758) ABC_tran_CTD PF16326.5 EPE27945.1 - 0.2 11.9 1.8 2.8 8.3 0.1 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain Hrs_helical PF12210.8 EPE27945.1 - 0.23 12.0 2.8 0.18 12.3 1.0 1.7 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Ribonucleas_3_3 PF14622.6 EPE27946.1 - 9.7e-28 96.9 0.0 2e-27 95.9 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EPE27946.1 - 6.5e-06 26.7 0.0 2.3e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain HAT_KAT11 PF08214.11 EPE27947.1 - 7.9e-100 334.5 0.0 1.1e-99 334.0 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein ER-remodelling PF14755.6 EPE27947.1 - 0.29 11.4 6.4 9.9 6.4 0.2 2.9 2 0 0 2 2 2 0 Intracellular membrane remodeller Fungus-induced PF10917.8 EPE27948.1 - 0.022 15.1 0.2 6.6 7.1 0.1 2.5 2 0 0 2 2 2 0 Fungus-induced protein DUF4937 PF16291.5 EPE27949.1 - 0.014 15.6 0.2 0.026 14.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 RTA1 PF04479.13 EPE27950.1 - 7.3e-51 172.7 7.9 1.1e-50 172.2 7.9 1.2 1 0 0 1 1 1 1 RTA1 like protein AA_permease_2 PF13520.6 EPE27951.1 - 2.3e-52 178.2 46.6 2.9e-52 178.0 46.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE27951.1 - 4.6e-19 68.4 35.4 5.9e-19 68.0 35.4 1.1 1 0 0 1 1 1 1 Amino acid permease E1-E2_ATPase PF00122.20 EPE27952.1 - 2.4e-36 124.9 11.8 2e-29 102.4 0.2 3.4 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EPE27952.1 - 2.4e-26 92.5 5.7 8.5e-26 90.8 5.7 2.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EPE27952.1 - 6.5e-21 75.6 0.0 4.7e-16 59.7 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPE27952.1 - 3e-17 62.5 0.0 7.6e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EPE27952.1 - 1e-16 60.3 0.0 3.1e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EPE27952.1 - 0.00032 20.5 0.2 0.0021 17.9 0.5 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HET PF06985.11 EPE27953.1 - 9.6e-29 100.6 0.5 1.5e-28 100.0 0.5 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LCCL PF03815.19 EPE27953.1 - 2.3e-20 72.5 0.2 4.9e-20 71.4 0.2 1.5 1 0 0 1 1 1 1 LCCL domain HET PF06985.11 EPE27956.1 - 5.8e-30 104.6 2.4 1e-29 103.8 2.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BTB PF00651.31 EPE27957.1 - 0.0067 16.7 0.0 0.27 11.5 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain TRAM_LAG1_CLN8 PF03798.16 EPE27959.1 - 4.5e-42 144.0 17.3 4.5e-42 144.0 17.3 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EPE27959.1 - 3.4e-17 61.9 0.0 3.4e-17 61.9 0.0 2.4 2 0 0 2 2 2 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.16 EPE27960.1 - 7.6e-36 123.7 20.4 7.6e-36 123.7 20.4 2.2 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EPE27960.1 - 3.3e-25 87.5 0.1 3.3e-25 87.5 0.1 2.2 3 0 0 3 3 3 1 TRAM1-like protein Mito_carr PF00153.27 EPE27961.1 - 3.2e-11 43.0 2.2 0.0048 16.8 0.0 4.3 3 2 0 3 3 3 3 Mitochondrial carrier protein CENP-T_C PF15511.6 EPE27962.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EPE27962.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EPE27962.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EPE27962.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EPE27962.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EPE27962.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EPE27962.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EPE27962.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 EPE27962.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Sedlin_N PF04628.13 EPE27963.1 - 1.2e-44 151.7 0.0 1.3e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EPE27963.1 - 0.0011 18.9 0.1 0.029 14.3 0.0 2.1 1 1 1 2 2 2 1 Sybindin-like family ArfA PF03889.13 EPE27963.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Alternative ribosome-rescue factor A L31 PF09784.9 EPE27964.1 - 5.6e-42 142.3 1.1 6.3e-42 142.2 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 RRM_1 PF00076.22 EPE27965.1 - 3.3e-15 55.7 0.0 4.7e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1492 PF07374.11 EPE27966.1 - 0.074 13.2 1.2 0.23 11.6 1.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) zf_UBZ PF18439.1 EPE27971.1 - 0.0024 17.4 6.8 2.3 7.9 0.2 3.9 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 EPE27971.1 - 0.0061 17.0 0.2 0.0061 17.0 0.2 4.6 5 0 0 5 5 5 1 Zinc finger, C2H2 type zf-C2HE PF16278.5 EPE27971.1 - 0.012 16.0 4.0 11 6.6 0.3 3.8 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_4 PF13894.6 EPE27971.1 - 0.12 13.2 15.9 0.71 10.9 0.2 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger zinc_ribbon_5 PF13719.6 EPE27971.1 - 0.54 10.1 0.0 0.54 10.1 0.0 2.8 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_12 PF11331.8 EPE27971.1 - 0.59 10.0 2.9 0.41 10.5 0.3 2.1 2 0 0 2 2 2 0 Probable zinc-ribbon domain Rtf2 PF04641.12 EPE27971.1 - 1.3 8.3 6.0 0.68 9.2 0.2 2.4 2 1 0 2 2 2 0 Rtf2 RING-finger zinc_ribbon_4 PF13717.6 EPE27971.1 - 1.6 8.8 6.6 0.59 10.1 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-met PF12874.7 EPE27971.1 - 1.7 9.2 4.0 54 4.4 0.0 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type IBR PF01485.21 EPE27971.1 - 4.8 7.5 13.6 4.5 7.6 3.7 3.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Peptidase_S28 PF05577.12 EPE27972.1 - 1.2e-43 149.5 1.0 2.8e-42 145.0 1.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 RAI16-like PF10257.9 EPE27973.1 - 3.7e-78 262.9 1.1 7.4e-78 261.9 1.1 1.4 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein Adeno_52K PF03052.15 EPE27973.1 - 0.076 12.4 0.1 0.43 10.0 0.0 2.1 1 1 1 2 2 2 0 Adenoviral protein L1 52/55-kDa ABC_tran PF00005.27 EPE27975.1 - 5e-46 156.6 0.1 5.7e-26 91.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EPE27975.1 - 5.5e-27 94.8 41.5 2.4e-14 53.2 14.2 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 EPE27975.1 - 4.2e-17 62.9 2.5 3.5e-05 23.8 0.0 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EPE27975.1 - 3.4e-06 27.7 3.3 0.033 14.7 0.4 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EPE27975.1 - 8.4e-06 25.4 3.3 0.013 14.9 0.1 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EPE27975.1 - 1.5e-05 24.8 0.1 0.28 10.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EPE27975.1 - 1.9e-05 24.3 1.5 0.12 12.1 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_19 PF13245.6 EPE27975.1 - 8.6e-05 22.9 1.9 0.036 14.4 0.2 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EPE27975.1 - 0.00012 22.0 0.1 5.4 6.6 0.5 3.2 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 EPE27975.1 - 0.00021 21.2 2.3 0.077 12.9 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EPE27975.1 - 0.0023 18.3 0.1 2.3 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 EPE27975.1 - 0.0076 15.5 0.2 0.063 12.6 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin Rad4 PF03835.15 EPE27975.1 - 0.0087 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain AAA_22 PF13401.6 EPE27975.1 - 0.011 16.0 0.1 7.3 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EPE27975.1 - 0.014 15.9 0.9 5.3 7.5 0.2 3.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EPE27975.1 - 0.015 15.7 0.0 4.6 7.7 0.0 3.1 3 0 0 3 3 2 0 RNA helicase MukB PF04310.12 EPE27975.1 - 0.026 14.4 2.2 0.45 10.3 0.1 2.6 3 0 0 3 3 2 0 MukB N-terminal AAA_24 PF13479.6 EPE27975.1 - 0.053 13.2 1.1 19 4.9 0.0 3.6 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 EPE27975.1 - 0.1 12.5 0.2 2 8.3 0.1 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 EPE27975.1 - 0.12 11.9 2.3 3.2 7.3 0.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF4162 PF13732.6 EPE27975.1 - 0.13 13.0 0.0 12 6.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_28 PF13521.6 EPE27975.1 - 0.14 12.4 2.5 2.6 8.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 EPE27975.1 - 0.28 10.7 1.7 19 4.7 0.0 3.3 3 0 0 3 3 3 0 P-loop containing dynein motor region TPR_1 PF00515.28 EPE27976.1 - 5.7e-35 117.7 15.5 2.4e-07 30.3 0.0 8.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 EPE27976.1 - 7.7e-34 113.1 25.7 4.9e-06 26.2 0.0 10.4 11 1 0 11 11 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE27976.1 - 4.8e-26 90.8 20.7 1e-19 70.5 4.8 5.0 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EPE27976.1 - 1.6e-25 87.2 15.9 0.001 19.1 0.0 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 EPE27976.1 - 8.9e-20 71.1 8.3 7.1e-05 23.4 0.1 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EPE27976.1 - 3e-17 62.7 18.2 2.9e-05 24.2 0.0 8.2 5 3 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EPE27976.1 - 4.8e-16 58.1 11.7 0.071 14.0 0.0 9.3 5 2 6 11 11 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 EPE27976.1 - 4.9e-13 48.1 7.4 1.1 9.5 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 EPE27976.1 - 3.9e-12 45.6 12.6 0.0037 16.9 0.7 7.8 6 2 2 8 8 8 3 TPR repeat TPR_19 PF14559.6 EPE27976.1 - 6.9e-11 42.5 19.2 0.022 15.2 0.2 7.3 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 EPE27976.1 - 6.5e-10 39.0 14.5 0.96 10.2 0.5 9.2 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPE27976.1 - 1.3e-09 37.7 17.9 1.2 9.7 0.1 9.7 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_9 PF13371.6 EPE27976.1 - 5.7e-09 36.0 2.2 0.16 12.2 0.1 6.1 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 EPE27976.1 - 0.0078 16.5 0.6 1.3 9.4 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat PknG_TPR PF16918.5 EPE27976.1 - 0.0096 14.7 0.1 0.021 13.6 0.1 1.6 1 0 0 1 1 1 1 Protein kinase G tetratricopeptide repeat TPR_10 PF13374.6 EPE27976.1 - 0.24 11.3 8.1 0.3 11.0 0.2 5.1 7 0 0 7 7 6 0 Tetratricopeptide repeat TMEM208_SND2 PF05620.11 EPE27977.1 - 9e-53 178.5 0.0 1e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF3605 PF12239.8 EPE27978.1 - 2.2e-57 193.7 0.0 2.7e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) NAD_binding_1 PF00175.21 EPE27979.1 - 1.5e-27 96.4 0.0 2.3e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EPE27979.1 - 2.8e-27 94.9 0.0 4.4e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EPE27979.1 - 1.8e-05 24.9 0.0 0.00089 19.4 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain ProQ_C PF17516.2 EPE27979.1 - 0.18 11.3 0.5 2.5 7.6 0.1 2.4 2 0 0 2 2 2 0 ProQ C-terminal domain ATG_C PF09333.11 EPE27980.1 - 8.7e-09 35.6 0.0 1.2e-06 28.7 0.0 2.4 2 1 0 2 2 2 2 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EPE27980.1 - 0.1 12.4 1.1 0.39 10.5 0.6 2.0 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal Methyltransf_23 PF13489.6 EPE27981.1 - 3.6e-21 75.7 0.0 5.9e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE27981.1 - 1.7e-10 41.5 0.0 3.9e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE27981.1 - 3.5e-09 36.6 0.0 3.2e-08 33.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE27981.1 - 2e-07 31.6 0.0 3.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE27981.1 - 7.6e-07 29.8 0.0 4.3e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EPE27981.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 EPE27981.1 - 0.032 13.8 0.0 0.076 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 EPE27981.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Clathrin_lg_ch PF01086.17 EPE27982.1 - 8.8e-78 261.5 5.1 9.9e-78 261.3 5.1 1.0 1 0 0 1 1 1 1 Clathrin light chain CDC37_N PF03234.14 EPE27983.1 - 9.6e-48 162.3 2.4 9.6e-48 162.3 2.4 3.1 3 1 1 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EPE27983.1 - 2.7e-41 140.2 0.3 9e-41 138.5 0.0 2.0 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EPE27983.1 - 3.1e-34 117.1 2.3 3.1e-34 117.1 2.3 2.6 2 0 0 2 2 2 1 Cdc37 C terminal domain ABC_membrane PF00664.23 EPE27984.1 - 2.8e-51 174.8 9.1 3.6e-51 174.4 9.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EPE27984.1 - 2.8e-34 118.6 0.0 8.7e-34 117.0 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EPE27984.1 - 4.8e-05 22.9 0.0 0.00014 21.4 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EPE27984.1 - 0.016 15.5 0.0 0.073 13.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EPE27984.1 - 0.018 15.4 0.1 0.077 13.4 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EPE27984.1 - 0.025 14.3 1.9 0.037 13.8 0.3 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 EPE27984.1 - 0.091 13.0 0.9 1.2 9.4 0.9 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PH_10 PF15411.6 EPE27986.1 - 3.3e-28 98.4 0.4 6.7e-28 97.4 0.4 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 EPE27986.1 - 2e-15 57.5 0.0 3.7e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EPE27986.1 - 2.7e-09 37.1 0.4 3.4e-08 33.6 0.4 2.4 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 EPE27986.1 - 6.2e-05 23.3 5.0 0.00011 22.5 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EPE27986.1 - 0.00076 19.4 5.6 0.0013 18.7 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EPE27986.1 - 0.003 17.8 2.5 0.0065 16.7 2.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EPE27986.1 - 0.0034 17.2 4.3 0.0062 16.3 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE27986.1 - 0.0041 17.0 5.2 0.0075 16.1 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EPE27986.1 - 0.0045 16.6 2.7 0.0045 16.6 2.7 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EPE27986.1 - 0.0072 16.2 1.8 0.014 15.3 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EPE27986.1 - 0.068 13.5 4.3 0.12 12.7 4.3 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 EPE27986.1 - 0.13 12.1 3.6 0.26 11.1 3.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger Rtf2 PF04641.12 EPE27986.1 - 0.17 11.2 0.3 0.36 10.2 0.3 1.5 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1147 PF06615.11 EPE27986.1 - 0.23 11.5 0.3 0.55 10.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) Prok-RING_4 PF14447.6 EPE27986.1 - 0.77 9.7 2.9 1.4 8.8 2.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 EPE27986.1 - 2.2 8.4 5.7 4.5 7.4 5.7 1.6 1 0 0 1 1 1 0 Zinc-finger zf-RING_UBOX PF13445.6 EPE27986.1 - 4 7.5 5.5 10 6.2 5.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger DUF5016 PF16408.5 EPE27987.1 - 0.19 11.7 0.2 0.35 10.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5016) Neurochondrin PF05536.11 EPE27988.1 - 8.3e-71 239.1 1.6 1.1e-70 238.7 1.6 1.2 1 0 0 1 1 1 1 Neurochondrin Voltage_CLC PF00654.20 EPE27989.1 - 8.1e-88 295.0 31.7 8.1e-88 295.0 31.7 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EPE27989.1 - 0.013 15.9 0.0 0.089 13.2 0.1 2.2 2 0 0 2 2 2 0 CBS domain Ank_2 PF12796.7 EPE27990.1 - 7.8e-28 96.9 22.4 3.4e-05 24.3 0.3 12.3 10 2 3 13 13 13 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE27990.1 - 5.6e-16 58.7 21.3 0.0016 18.9 0.0 13.0 10 3 4 14 14 14 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE27990.1 - 1.2e-05 25.3 22.2 56 4.8 0.0 14.3 16 1 1 17 17 17 0 Ankyrin repeat Ank_5 PF13857.6 EPE27990.1 - 0.00069 19.9 10.1 0.012 15.9 0.1 7.3 8 0 0 8 8 8 1 Ankyrin repeats (many copies) Glyco_transf_8 PF01501.20 EPE27991.1 - 3.6e-15 56.2 7.4 4.5e-14 52.6 7.4 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EPE27991.1 - 0.0035 16.7 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Fer4_2 PF12797.7 EPE27992.1 - 0.1 12.7 2.1 8.2 6.7 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Pkinase PF00069.25 EPE27993.1 - 5.6e-53 180.0 0.0 9.3e-53 179.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE27993.1 - 4.8e-26 91.6 0.0 6.7e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EPE27993.1 - 1e-11 45.0 0.4 3.7e-11 43.2 0.1 2.2 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.6 EPE27993.1 - 9e-06 25.2 0.0 0.0002 20.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EPE27993.1 - 1.4e-05 24.1 0.0 3.3e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EPE27993.1 - 0.0004 19.8 0.0 0.0011 18.3 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPE27993.1 - 0.00084 19.3 0.0 0.022 14.7 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Yop-YscD_cpl PF16697.5 EPE27993.1 - 0.001 19.4 0.0 0.0048 17.2 0.0 2.1 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RNA_pol_I_A49 PF06870.12 EPE27994.1 - 7.6e-90 301.5 3.0 8.8e-90 301.3 3.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Asp PF00026.23 EPE27997.1 - 8e-72 242.3 3.5 1e-71 242.0 3.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPE27997.1 - 2.4e-13 50.7 2.8 5.4e-11 43.0 1.1 3.8 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EPE27997.1 - 8.8e-06 25.6 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EPE27997.1 - 1.6e-05 25.5 2.9 0.3 11.7 0.1 4.2 3 2 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EPE27997.1 - 0.004 17.7 0.9 4.3 8.0 0.0 4.2 2 2 1 3 3 3 1 gag-polyprotein putative aspartyl protease Pep3_Vps18 PF05131.14 EPE27998.1 - 3e-51 173.1 0.1 9.6e-51 171.5 0.0 1.9 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EPE27998.1 - 1.1e-11 44.8 5.3 1.6e-08 34.5 0.0 3.5 2 1 0 2 2 2 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 EPE27998.1 - 0.00036 20.1 0.1 0.0007 19.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EPE27998.1 - 0.00039 20.2 1.0 0.00094 19.0 1.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.9 EPE27998.1 - 0.0011 19.3 1.1 0.045 14.0 0.0 2.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_5 PF14634.6 EPE27998.1 - 0.0015 18.4 0.5 0.003 17.5 0.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EPE27998.1 - 0.0019 18.5 0.9 0.0044 17.3 0.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EPE27998.1 - 0.0024 17.6 4.3 0.0047 16.6 4.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EPE27998.1 - 0.0099 15.9 0.6 0.02 14.9 0.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Vps39_2 PF10367.9 EPE27998.1 - 0.016 15.6 0.3 0.06 13.8 0.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.7 EPE27998.1 - 0.037 14.3 0.2 0.095 13.0 0.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EPE27998.1 - 0.059 13.3 0.3 0.15 11.9 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) dCMP_cyt_deam_2 PF08211.12 EPE27998.1 - 0.069 13.4 0.0 3 8.1 0.0 2.5 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region zf-C3H2C3 PF17122.5 EPE27998.1 - 0.087 12.9 1.7 0.17 12.0 1.7 1.5 1 0 0 1 1 1 0 Zinc-finger DHH PF01368.20 EPE27999.1 - 0.0087 16.3 0.0 0.22 11.8 0.0 2.4 2 0 0 2 2 2 1 DHH family Pkinase PF00069.25 EPE28000.1 - 2e-68 230.7 0.0 2.4e-67 227.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE28000.1 - 5.6e-49 166.8 0.0 8.7e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 EPE28000.1 - 2.1e-27 95.4 0.0 3.6e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 EPE28000.1 - 1.3e-17 63.9 0.1 2.8e-17 62.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EPE28000.1 - 2.2e-17 62.9 0.1 4.8e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EPE28000.1 - 5.4e-10 39.8 0.1 9.2e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 EPE28000.1 - 1.3e-07 31.2 0.0 1.9e-05 24.1 0.0 2.5 3 0 0 3 3 3 1 Kinase-like SAM_PNT PF02198.16 EPE28000.1 - 0.0067 16.4 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 EPE28000.1 - 0.069 13.4 0.6 0.16 12.2 0.6 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Pkinase_fungal PF17667.1 EPE28000.1 - 0.07 11.9 0.1 0.17 10.6 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase SAM_4 PF18017.1 EPE28000.1 - 0.12 12.3 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) HATPase_c_3 PF13589.6 EPE28001.1 - 4e-15 55.9 0.2 1.1e-14 54.4 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 EPE28001.1 - 1.2e-10 41.1 0.0 3.5e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 EPE28001.1 - 2e-08 34.8 0.1 1.3e-07 32.1 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4363 PF14276.6 EPE28001.1 - 0.051 13.7 0.2 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Ank_2 PF12796.7 EPE28002.1 - 5.2e-33 113.5 1.5 6.8e-10 39.4 0.0 5.5 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE28002.1 - 6.7e-26 90.3 3.4 1.7e-08 34.8 0.1 6.3 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EPE28002.1 - 3.4e-20 71.5 5.3 0.011 16.1 0.0 8.2 8 0 0 8 8 8 5 Ankyrin repeat Ank_3 PF13606.6 EPE28002.1 - 2.7e-18 64.2 3.4 0.0015 18.8 0.0 7.6 7 0 0 7 7 6 4 Ankyrin repeat Ank_5 PF13857.6 EPE28002.1 - 4.6e-15 55.5 2.4 0.00012 22.3 0.0 5.2 5 1 0 5 5 5 3 Ankyrin repeats (many copies) NACHT PF05729.12 EPE28002.1 - 4e-10 39.9 0.0 2e-09 37.6 0.0 2.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EPE28002.1 - 4.8e-05 23.8 0.0 0.00023 21.6 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EPE28002.1 - 0.00064 19.0 0.1 0.0032 16.7 0.1 2.0 1 1 0 1 1 1 1 NB-ARC domain AAA PF00004.29 EPE28002.1 - 0.0043 17.5 0.0 0.013 15.9 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EPE28002.1 - 0.0052 16.8 0.2 0.31 11.1 0.1 3.0 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EPE28002.1 - 0.018 15.4 0.0 0.051 14.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 EPE28002.1 - 0.018 15.3 0.0 0.061 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain SesA PF17107.5 EPE28002.1 - 0.027 14.7 2.4 0.12 12.6 0.0 3.1 4 0 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases ABC_tran PF00005.27 EPE28002.1 - 0.13 12.7 0.0 0.47 11.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter ApoLp-III PF07464.11 EPE28002.1 - 0.22 11.6 0.4 4 7.5 0.5 2.8 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) tRNA-synt_1 PF00133.22 EPE28003.1 - 2.6e-217 722.9 1.7 3.7e-216 719.0 1.7 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EPE28003.1 - 1.2e-32 113.0 0.1 2.7e-32 111.8 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EPE28003.1 - 2.6e-14 52.8 0.1 3.3e-06 26.1 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EPE28003.1 - 9.8e-12 44.8 4.2 8.8e-09 35.1 0.0 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 EPE28003.1 - 0.0019 18.5 7.3 0.0019 18.5 7.3 2.8 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 EPE28003.1 - 0.0088 15.4 0.0 0.092 12.1 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain FAM199X PF15814.5 EPE28003.1 - 7.6 5.5 10.9 4 6.4 3.3 2.2 2 0 0 2 2 2 0 Protein family FAM199X DUF1771 PF08590.10 EPE28004.1 - 5.7e-15 55.5 10.9 1.6e-14 54.0 10.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 EPE28004.1 - 1e-08 35.0 7.6 4.7e-06 26.5 0.6 2.9 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 EPE28004.1 - 6.7e-08 32.8 0.0 2e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.24 EPE28004.1 - 1.8e-06 27.7 0.6 0.0055 16.6 0.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EPE28004.1 - 0.00012 21.8 10.0 0.0023 17.7 0.4 3.1 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EPE28004.1 - 0.00013 22.3 4.1 0.27 11.7 0.2 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger CUE PF02845.16 EPE28004.1 - 0.069 12.9 0.0 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 CUE domain zf-CCCH_3 PF15663.5 EPE28004.1 - 0.071 13.3 5.3 5.7 7.2 2.7 2.3 1 1 1 2 2 2 0 Zinc-finger containing family Torus PF16131.5 EPE28004.1 - 0.43 11.3 3.9 2 9.1 0.6 2.3 1 1 1 2 2 2 0 Torus domain APH PF01636.23 EPE28005.1 - 3.2e-11 43.6 0.0 4.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EPE28005.1 - 0.0076 15.1 0.0 0.0096 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) CTP_synth_N PF06418.14 EPE28006.1 - 3.5e-95 318.3 0.0 4.9e-95 317.8 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EPE28006.1 - 3.8e-57 193.1 0.0 5.4e-57 192.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EPE28006.1 - 1.5e-05 24.9 0.8 0.00033 20.5 0.8 2.5 1 1 0 1 1 1 1 Peptidase C26 SARAF PF06682.12 EPE28007.1 - 2.8e-47 162.0 6.8 3.6e-45 155.1 0.1 2.0 1 1 1 2 2 2 2 SOCE-associated regulatory factor of calcium homoeostasis DnaJ_C PF01556.18 EPE28008.1 - 1.5e-37 128.9 0.7 2e-37 128.5 0.7 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EPE28008.1 - 7.5e-27 93.3 5.6 1.4e-26 92.4 5.6 1.5 1 0 0 1 1 1 1 DnaJ domain PLDc_2 PF13091.6 EPE28009.1 - 1.8e-13 50.5 0.0 2.2e-06 27.6 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EPE28009.1 - 5.2e-11 42.2 0.4 5.8e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif NDUFA12 PF05071.16 EPE28010.1 - 1.2e-31 109.4 1.8 1.4e-31 109.2 1.8 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ArgJ PF01960.18 EPE28012.1 - 5.7e-151 502.5 0.0 6.6e-151 502.3 0.0 1.0 1 0 0 1 1 1 1 ArgJ family HGTP_anticodon2 PF12745.7 EPE28013.1 - 4.3e-84 282.1 1.0 4.3e-84 282.1 1.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 EPE28013.1 - 7e-82 274.7 3.5 7.3e-37 127.2 0.0 4.3 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 EPE28013.1 - 5.2e-49 166.9 0.8 6e-20 71.6 0.0 3.9 4 0 0 4 4 4 3 Protein tyrosine kinase RWD PF05773.22 EPE28013.1 - 6.9e-14 52.1 0.1 2.3e-13 50.5 0.1 2.0 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 EPE28013.1 - 8.7e-14 51.5 0.0 3.1e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 EPE28013.1 - 2.2e-05 23.9 0.0 0.19 11.0 0.0 2.8 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EPE28013.1 - 0.0071 16.3 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EPE28013.1 - 0.028 14.0 0.5 0.69 9.5 0.0 2.9 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EPE28013.1 - 0.051 12.9 0.2 7.5 5.8 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ydr279_N PF17745.1 EPE28013.1 - 0.095 13.0 0.2 74 3.7 0.0 4.2 4 1 0 4 4 4 0 Ydr279p protein triple barrel domain DUF1682 PF07946.14 EPE28013.1 - 0.19 10.9 9.1 0.38 9.9 9.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PDT PF00800.18 EPE28014.1 - 5.5e-55 186.0 0.0 5.8e-53 179.4 0.0 2.1 2 0 0 2 2 2 2 Prephenate dehydratase ACT PF01842.25 EPE28014.1 - 0.00047 19.9 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 ACT domain MaoC_dehydratas PF01575.19 EPE28015.1 - 6.4e-05 22.5 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain LRR_6 PF13516.6 EPE28016.1 - 0.19 11.8 9.7 48 4.4 0.0 5.9 5 0 0 5 5 5 0 Leucine Rich repeat FolB PF02152.18 EPE28017.1 - 2.2e-27 95.8 0.0 1e-19 71.1 0.1 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase FYVE PF01363.21 EPE28018.1 - 1.9e-20 72.7 2.1 1.9e-20 72.7 2.1 2.5 2 0 0 2 2 2 1 FYVE zinc finger FYVE_2 PF02318.16 EPE28018.1 - 0.0097 16.1 1.2 0.0097 16.1 1.2 2.4 2 0 0 2 2 2 1 FYVE-type zinc finger DUF1501 PF07394.12 EPE28018.1 - 0.13 11.3 1.0 0.21 10.6 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) zf-B_box PF00643.24 EPE28018.1 - 0.41 10.8 6.5 1.5 9.1 6.5 2.0 1 0 0 1 1 1 0 B-box zinc finger DZR PF12773.7 EPE28018.1 - 0.45 10.6 9.0 1.6 8.8 5.4 2.7 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_2 PF13639.6 EPE28018.1 - 5.2 7.5 20.0 3.3 8.1 1.1 3.0 3 0 0 3 3 3 0 Ring finger domain zf-piccolo PF05715.13 EPE28018.1 - 5.4 7.2 9.7 3.2 8.0 5.6 2.5 2 0 0 2 2 2 0 Piccolo Zn-finger UDPGP PF01704.18 EPE28019.1 - 5.4e-190 631.4 0.1 6.5e-190 631.1 0.1 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.6 EPE28019.1 - 0.048 12.5 2.5 0.5 9.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4301) HeLo PF14479.6 EPE28020.1 - 4.7e-25 88.6 0.0 7.6e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 EPE28020.1 - 0.058 12.8 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Ank_2 PF12796.7 EPE28021.1 - 2.8e-26 91.9 0.2 3.6e-08 33.9 0.0 6.8 5 1 3 8 8 8 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE28021.1 - 3.7e-21 74.9 2.6 1.6e-05 25.0 0.0 7.1 6 1 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE28021.1 - 5.1e-21 72.5 7.3 0.0055 17.1 0.0 9.3 10 0 0 10 10 10 5 Ankyrin repeat Pkinase PF00069.25 EPE28021.1 - 2.9e-19 69.4 0.0 4.8e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 EPE28021.1 - 2.9e-18 66.0 2.9 0.00058 20.4 0.1 7.4 6 1 2 8 8 8 3 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 EPE28021.1 - 2.6e-15 56.4 0.0 5.9e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ank PF00023.30 EPE28021.1 - 3.6e-14 52.5 3.4 0.041 14.3 0.2 8.0 7 0 0 7 7 7 3 Ankyrin repeat APH PF01636.23 EPE28021.1 - 0.056 13.4 0.4 1.4 8.8 0.0 2.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EPE28021.1 - 0.09 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NUC205 PF08168.11 EPE28021.1 - 0.13 11.8 0.2 0.28 10.7 0.2 1.5 1 0 0 1 1 1 0 NUC205 domain Sigma_reg_N PF13800.6 EPE28022.1 - 0.074 13.3 0.2 0.12 12.7 0.2 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Herpes_US9 PF06072.11 EPE28022.1 - 0.12 12.3 1.2 0.19 11.6 1.2 1.3 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF3605 PF12239.8 EPE28023.1 - 1.8e-57 194.0 1.9 2.1e-57 193.7 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) CelTOS PF18659.1 EPE28023.1 - 0.041 14.3 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites Hist_deacetyl PF00850.19 EPE28024.1 - 2.9e-80 270.0 0.0 3.7e-80 269.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.7 EPE28025.1 - 1.9e-20 73.3 3.4 2.7e-20 72.8 3.4 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EPE28025.1 - 2.6e-05 24.0 7.7 4.5e-05 23.2 7.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-CCCH PF00642.24 EPE28026.1 - 4.4e-08 32.8 19.3 4.6e-07 29.6 2.5 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EPE28026.1 - 0.00047 19.9 0.0 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EPE28026.1 - 0.0058 16.7 3.3 0.0058 16.7 3.3 3.2 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 EPE28026.1 - 0.037 14.7 4.7 0.62 10.8 0.2 2.7 3 0 0 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 EPE28026.1 - 1.8 8.8 7.7 0.54 10.5 1.2 2.4 2 2 0 2 2 2 0 Zinc-finger containing family Cys_Met_Meta_PP PF01053.20 EPE28027.1 - 1.3e-55 188.5 0.0 5.8e-55 186.4 0.0 2.0 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EPE28027.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V C2 PF00168.30 EPE28028.1 - 4.4e-76 251.8 0.2 1.5e-20 73.4 0.0 5.5 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 EPE28028.1 - 8.6e-05 22.1 0.0 0.00026 20.5 0.0 1.8 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain MLVIN_C PF18697.1 EPE28028.1 - 0.12 12.5 0.1 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain TRP PF06011.12 EPE28031.1 - 8.7e-40 136.7 17.8 1.8e-30 106.0 15.7 2.2 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EPE28031.1 - 1.5e-22 80.4 0.1 2.4e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 ML-like domain Strabismus PF06638.11 EPE28031.1 - 0.4 9.3 2.9 0.68 8.5 2.9 1.3 1 0 0 1 1 1 0 Strabismus protein DUF4271 PF14093.6 EPE28031.1 - 0.92 9.4 13.8 0.44 10.4 11.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) Oxysterol_BP PF01237.18 EPE28032.1 - 2.3e-61 207.7 0.1 9.2e-59 199.1 0.1 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein MFS_1 PF07690.16 EPE28033.1 - 8.2e-14 51.3 21.4 8.2e-14 51.3 21.4 2.4 1 1 2 3 3 3 1 Major Facilitator Superfamily TMEM208_SND2 PF05620.11 EPE28033.1 - 0.038 13.8 0.1 0.038 13.8 0.1 2.8 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 Cu-oxidase_2 PF07731.14 EPE28034.1 - 1.3e-42 144.8 7.9 2.7e-41 140.5 0.6 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EPE28034.1 - 4.4e-38 129.9 2.9 4.4e-38 129.9 2.9 3.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EPE28034.1 - 9.2e-31 107.1 0.1 4.4e-29 101.6 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Zn_clus PF00172.18 EPE28035.1 - 1.4e-05 25.1 11.2 2.3e-05 24.4 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE28035.1 - 0.0058 15.7 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MerR-DNA-bind PF09278.11 EPE28035.1 - 0.13 12.9 0.5 0.28 11.8 0.5 1.5 1 0 0 1 1 1 0 MerR, DNA binding NAD_binding_10 PF13460.6 EPE28036.1 - 1.1e-08 35.2 0.0 1.5e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE28036.1 - 5.3e-05 22.8 0.0 8.2e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE28036.1 - 0.0017 17.4 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 EPE28036.1 - 0.0032 17.6 0.1 0.017 15.3 0.0 2.2 2 1 1 3 3 3 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 EPE28036.1 - 0.0093 15.2 0.1 0.07 12.3 0.0 2.2 1 1 0 2 2 2 1 Male sterility protein NmrA PF05368.13 EPE28036.1 - 0.048 13.2 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 EPE28036.1 - 0.052 12.6 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EPE28036.1 - 0.077 12.1 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PDE8 PF08629.10 EPE28036.1 - 0.085 12.9 0.3 0.19 11.8 0.3 1.6 1 0 0 1 1 1 0 PDE8 phosphodiesterase Phage_holin_3_6 PF07332.11 EPE28037.1 - 0.029 14.4 15.5 0.032 14.3 0.1 4.0 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III FMN_dh PF01070.18 EPE28038.1 - 3.1e-104 348.7 0.0 3.9e-104 348.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EPE28038.1 - 5.2e-17 61.8 0.0 2.2e-16 59.8 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EPE28038.1 - 5.8e-07 29.0 0.1 8.8e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EPE28038.1 - 6.2e-05 22.1 0.0 0.00022 20.3 0.0 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EPE28038.1 - 0.028 13.9 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.15 EPE28038.1 - 0.069 12.5 0.2 0.12 11.8 0.2 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Ribul_P_3_epim PF00834.19 EPE28038.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family HBS1_N PF08938.10 EPE28038.1 - 0.16 12.3 0.4 7.3 7.0 0.0 3.0 3 0 0 3 3 3 0 HBS1 N-terminus DHO_dh PF01180.21 EPE28038.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Na_Ca_ex PF01699.24 EPE28039.1 - 6.3e-53 178.8 49.2 4.3e-29 101.4 19.4 3.5 4 0 0 4 4 4 2 Sodium/calcium exchanger protein MAPEG PF01124.18 EPE28039.1 - 0.00093 19.1 3.8 0.0028 17.5 1.5 3.0 3 0 0 3 3 3 1 MAPEG family Vpu PF00558.19 EPE28039.1 - 0.078 12.8 0.0 0.34 10.7 0.0 2.1 1 0 0 1 1 1 0 Vpu protein Cnd2 PF05786.14 EPE28040.1 - 8e-96 322.4 3.1 9.6e-96 322.2 3.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EPE28040.1 - 0.00064 19.9 0.0 0.0022 18.2 0.0 1.9 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal PGA2 PF07543.12 EPE28040.1 - 0.26 11.2 4.4 0.37 10.8 0.6 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 Cnd2 PF05786.14 EPE28041.1 - 1.5e-223 744.8 0.6 1.8e-223 744.5 0.6 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Podoplanin PF05808.11 EPE28043.1 - 0.00074 19.7 3.2 0.0022 18.1 3.2 1.7 1 0 0 1 1 1 1 Podoplanin CcmD PF04995.14 EPE28043.1 - 0.0073 16.4 0.8 0.016 15.3 0.8 1.5 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) VSP PF03302.13 EPE28043.1 - 0.0074 15.2 1.4 0.012 14.5 1.4 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Mid2 PF04478.12 EPE28043.1 - 0.0089 15.9 0.2 0.021 14.7 0.2 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 EPE28043.1 - 0.015 14.7 1.8 0.032 13.6 1.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 EPE28043.1 - 0.022 14.7 0.3 0.05 13.5 0.3 1.6 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 EPE28043.1 - 0.034 15.0 0.0 0.069 14.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.6 EPE28043.1 - 0.097 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Amnionless Shisa PF13908.6 EPE28043.1 - 3.3 7.9 6.5 1.8 8.8 0.1 2.6 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator PH PF00169.29 EPE28044.1 - 2.2e-07 31.3 2.6 2.7e-06 27.8 0.0 3.4 3 1 0 3 3 3 1 PH domain PH_9 PF15410.6 EPE28044.1 - 0.0085 16.5 2.3 0.017 15.5 0.0 2.6 3 0 0 3 3 3 1 Pleckstrin homology domain SpoIIE PF07228.12 EPE28045.1 - 0.00023 21.1 0.0 0.0011 18.9 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EPE28045.1 - 0.0033 17.1 0.0 0.14 11.8 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C COesterase PF00135.28 EPE28046.1 - 4e-71 240.4 0.3 5.3e-71 240.0 0.3 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE28046.1 - 0.0024 17.8 0.4 0.0086 16.0 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE28046.1 - 0.01 16.5 1.0 0.017 15.7 0.1 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE28046.1 - 0.021 14.5 0.8 0.072 12.7 0.2 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1749 PF08538.10 EPE28046.1 - 0.042 12.9 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF2384 PF09722.10 EPE28046.1 - 0.076 13.1 0.1 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) NUFIP2 PF15293.6 EPE28046.1 - 0.14 11.1 0.5 0.21 10.5 0.5 1.1 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 Jag_N PF14804.6 EPE28048.1 - 0.14 12.5 0.9 0.32 11.4 0.9 1.6 1 0 0 1 1 1 0 Jag N-terminus Spherulin4 PF12138.8 EPE28049.1 - 2.6e-58 197.5 0.3 3e-58 197.3 0.3 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Pkinase PF00069.25 EPE28050.1 - 1.1e-69 234.8 0.0 1.5e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE28050.1 - 2.3e-41 141.8 0.0 3.2e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE28050.1 - 1.3e-10 41.1 0.2 1.1e-08 34.7 0.0 2.9 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 EPE28050.1 - 0.00019 20.9 0.3 0.0003 20.2 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EPE28050.1 - 0.026 14.2 0.0 0.079 12.6 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EPE28050.1 - 0.033 13.0 0.1 0.063 12.0 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 EPE28050.1 - 0.056 12.4 1.3 0.12 11.3 1.3 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Cutinase PF01083.22 EPE28051.1 - 6.4e-47 159.8 0.0 7.5e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EPE28051.1 - 0.001 18.7 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 EPE28051.1 - 0.04 13.8 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 EPE28051.1 - 0.14 11.7 0.1 0.2 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) preSET_CXC PF18264.1 EPE28052.1 - 1e-05 25.9 14.2 1.5 9.4 0.8 4.1 3 1 1 4 4 4 4 CXC domain Omega-toxin PF06357.11 EPE28052.1 - 0.0078 16.0 9.9 3.8 7.4 0.1 4.1 4 0 0 4 4 4 2 Omega-atracotoxin Defensin_int PF17858.1 EPE28052.1 - 0.04 13.9 16.5 1.2 9.2 0.7 4.0 2 1 2 4 4 4 0 Platypus intermediate defensin-like peptide Stealth_CR1 PF17101.5 EPE28052.1 - 0.08 12.7 1.9 11 5.8 0.0 3.8 4 0 0 4 4 4 0 Stealth protein CR1, conserved region 1 Trypan_PARP PF05887.11 EPE28052.1 - 3.1 7.8 13.1 1.9 8.4 3.1 2.2 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Iso_dh PF00180.20 EPE28053.1 - 3.5e-84 282.9 0.0 4.4e-84 282.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.8 EPE28055.1 - 2.4e-15 57.0 7.6 3.8e-15 56.4 7.6 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EPE28055.1 - 1.3e-10 41.8 0.0 2.2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE28055.1 - 1.6e-09 38.3 0.0 4.8e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EPE28055.1 - 0.00043 20.1 0.0 0.00078 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EPE28055.1 - 0.00072 20.3 0.0 0.0023 18.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EPE28055.1 - 0.0093 15.3 0.0 0.42 9.9 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EPE28055.1 - 0.027 14.3 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EPE28055.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3724 PF12521.8 EPE28055.1 - 0.083 12.8 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) Cor1 PF04803.12 EPE28056.1 - 0.0025 18.0 3.4 0.0046 17.2 2.7 1.7 1 1 1 2 2 2 1 Cor1/Xlr/Xmr conserved region Adhesin_P1_N PF18652.1 EPE28056.1 - 0.069 13.2 2.3 0.81 9.8 1.7 2.3 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain ColG_sub PF18496.1 EPE28056.1 - 0.13 12.4 0.3 0.26 11.4 0.3 1.4 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain G-patch PF01585.23 EPE28057.1 - 5.3e-08 32.6 0.0 3.4e-07 30.0 0.0 2.5 1 1 0 1 1 1 1 G-patch domain Rrn6 PF10214.9 EPE28057.1 - 1.2e-05 24.1 11.8 1.4e-05 23.9 11.8 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor G-patch_2 PF12656.7 EPE28057.1 - 0.49 10.5 0.0 0.49 10.5 0.0 3.5 4 1 0 4 4 4 0 G-patch domain GREB1 PF15782.5 EPE28057.1 - 4.6 4.2 18.8 5.4 4.0 18.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4855 PF16147.5 EPE28060.1 - 0.031 13.4 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4855) DinI PF06183.13 EPE28060.1 - 0.14 12.5 1.8 0.31 11.4 1.8 1.6 1 0 0 1 1 1 0 DinI-like family CdiI_4 PF18624.1 EPE28060.1 - 0.42 11.1 3.1 4.9 7.7 1.4 2.2 2 0 0 2 2 2 0 CDI immunity protein Sigma_reg_N PF13800.6 EPE28061.1 - 0.21 11.9 1.9 0.22 11.8 0.3 1.9 2 0 0 2 2 2 0 Sigma factor regulator N-terminal AAA_32 PF13654.6 EPE28063.1 - 0.058 12.2 0.1 0.089 11.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain CM2 PF03021.14 EPE28064.1 - 0.049 13.4 0.0 0.077 12.8 0.0 1.2 1 0 0 1 1 1 0 Influenza C virus M2 protein Alpha_GJ PF03229.13 EPE28064.1 - 0.078 13.5 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J TMEM132D_C PF15706.5 EPE28064.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Rax2 PF12768.7 EPE28065.1 - 0.034 13.6 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Fungal_trans_2 PF11951.8 EPE28066.1 - 4.6e-54 183.7 0.4 7.3e-54 183.0 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro_isomerase PF00160.21 EPE28066.1 - 4.3e-49 166.8 0.1 8.1e-49 165.9 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EPE28066.1 - 6e-11 42.7 0.1 0.00029 21.6 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Zn_clus PF00172.18 EPE28066.1 - 4.2e-08 33.2 7.5 8.6e-08 32.2 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ge1_WD40 PF16529.5 EPE28066.1 - 0.017 14.1 0.1 0.18 10.7 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EPE28066.1 - 0.019 15.3 0.0 6.6 7.1 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DTHCT PF08070.11 EPE28066.1 - 9.4 7.0 8.5 2 9.2 2.4 2.5 2 0 0 2 2 2 0 DTHCT (NUC029) region Far-17a_AIG1 PF04750.14 EPE28067.1 - 5.4e-51 172.8 12.1 6.2e-51 172.6 12.1 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein HhH-GPD PF00730.25 EPE28068.1 - 2.8e-05 24.5 0.1 0.0002 21.8 0.0 2.3 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Cytochrom_C1 PF02167.15 EPE28069.1 - 3e-94 314.8 0.0 3.8e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EPE28069.1 - 0.0065 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EPE28069.1 - 0.051 14.7 0.3 0.26 12.5 0.1 2.3 2 1 0 2 2 2 0 Cytochrome c DAHP_synth_1 PF00793.20 EPE28070.1 - 4.9e-102 340.5 0.0 6.2e-102 340.2 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family NAD_Gly3P_dh_N PF01210.23 EPE28071.1 - 1.9e-44 151.4 0.2 1.2e-43 148.8 0.1 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EPE28071.1 - 3.7e-42 144.0 0.1 6.4e-42 143.2 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus HABP4_PAI-RBP1 PF04774.15 EPE28071.1 - 0.17 12.7 0.6 0.4 11.5 0.6 1.5 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family hDGE_amylase PF14701.6 EPE28072.1 - 4.4e-180 599.5 0.0 5.6e-180 599.1 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EPE28072.1 - 2.4e-115 385.5 0.1 4.9e-115 384.5 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EPE28072.1 - 1e-88 297.3 0.0 1.9e-88 296.4 0.0 1.5 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EPE28072.1 - 1.8e-31 108.1 0.2 7.6e-31 106.1 0.0 2.3 3 0 0 3 3 3 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 EPE28072.1 - 0.0017 18.0 0.0 0.0067 16.0 0.0 1.8 2 0 0 2 2 2 1 Alpha amylase, catalytic domain TMEM208_SND2 PF05620.11 EPE28074.1 - 0.098 12.4 0.1 0.18 11.5 0.1 1.5 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 RNA_pol_Rpc4 PF05132.14 EPE28075.1 - 1.2 9.5 6.7 27 5.2 7.4 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 PDR_assoc PF08370.11 EPE28076.1 - 0.3 10.9 3.0 2.5 7.9 0.3 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated MCM PF00493.23 EPE28077.1 - 1.5e-101 338.2 0.0 2.4e-101 337.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EPE28077.1 - 1.3e-32 112.2 1.1 2.7e-32 111.3 1.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EPE28077.1 - 1.9e-21 76.3 1.2 4.4e-21 75.1 1.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EPE28077.1 - 1.8e-19 70.2 1.1 4.8e-19 68.9 1.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EPE28077.1 - 1.7e-07 30.8 0.0 1.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EPE28077.1 - 3.1e-06 27.2 0.0 1.2e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 EPE28077.1 - 0.0025 17.6 0.6 0.0072 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA lid domain phiKZ_IP PF12699.7 EPE28077.1 - 0.042 13.0 0.9 0.078 12.1 0.9 1.3 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins Mg_chelatase_C PF13335.6 EPE28077.1 - 0.064 13.9 0.3 0.29 11.8 0.2 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 EPE28077.1 - 0.07 13.0 0.0 0.22 11.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EPE28078.1 - 4.3e-55 185.7 0.0 2.6e-43 147.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EPE28078.1 - 1.3e-28 99.2 2.3 2.8e-28 98.1 0.5 2.4 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 EPE28078.1 - 1.7e-14 53.3 0.0 6.3e-09 35.5 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EPE28078.1 - 1.6e-10 41.6 3.6 0.00012 22.6 0.2 4.0 2 2 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 EPE28078.1 - 2e-06 28.4 0.1 0.017 15.7 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EPE28078.1 - 2.2e-06 27.7 0.1 0.025 14.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 EPE28078.1 - 2.3e-06 27.6 0.4 0.028 14.3 0.0 3.5 3 1 0 3 3 3 2 NACHT domain AAA_2 PF07724.14 EPE28078.1 - 2.8e-06 27.6 0.0 0.054 13.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EPE28078.1 - 4.3e-06 26.5 0.0 0.0086 15.8 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EPE28078.1 - 1.5e-05 25.2 0.2 0.15 12.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EPE28078.1 - 3e-05 23.7 0.4 0.45 10.1 0.1 3.4 2 1 1 3 3 3 2 AAA domain AAA_7 PF12775.7 EPE28078.1 - 3.2e-05 23.5 0.0 0.0027 17.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 EPE28078.1 - 4.5e-05 23.7 0.6 0.56 10.5 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_14 PF13173.6 EPE28078.1 - 5.7e-05 23.2 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EPE28078.1 - 7.6e-05 22.7 0.1 0.27 11.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EPE28078.1 - 0.00071 19.0 0.8 0.15 11.4 0.1 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EPE28078.1 - 0.00076 18.8 0.1 0.44 9.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.13 EPE28078.1 - 0.00098 18.4 0.0 0.79 8.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Sigma54_activat PF00158.26 EPE28078.1 - 0.0014 18.3 0.1 0.1 12.3 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EPE28078.1 - 0.0018 18.4 0.0 0.069 13.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 EPE28078.1 - 0.0019 18.0 0.3 2 8.1 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 EPE28078.1 - 0.0031 17.9 0.0 4.8 7.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.13 EPE28078.1 - 0.0039 16.4 0.0 0.086 12.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 EPE28078.1 - 0.006 17.1 0.0 3.7 8.1 0.0 2.9 2 0 0 2 2 2 1 ABC transporter KTI12 PF08433.10 EPE28078.1 - 0.0068 15.9 0.0 0.041 13.3 0.0 2.1 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 EPE28078.1 - 0.011 15.9 0.1 5.7 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EPE28078.1 - 0.018 14.8 0.0 0.3 10.9 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain APS_kinase PF01583.20 EPE28078.1 - 0.037 13.9 0.3 0.24 11.3 0.1 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase SKI PF01202.22 EPE28078.1 - 0.054 13.6 0.0 16 5.6 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_17 PF13207.6 EPE28078.1 - 0.058 13.8 0.4 1.5 9.3 0.1 3.0 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 EPE28078.1 - 0.074 12.8 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin2 PF13189.6 EPE28078.1 - 0.093 12.8 0.3 5 7.2 0.0 2.7 3 0 0 3 3 2 0 Cytidylate kinase-like family KAP_NTPase PF07693.14 EPE28078.1 - 0.095 11.9 0.1 0.34 10.1 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain NB-ARC PF00931.22 EPE28078.1 - 0.28 10.3 2.6 9.8 5.3 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain PEX-2N PF09263.10 EPE28078.1 - 0.28 11.5 4.5 2.8 8.3 0.0 3.4 4 0 0 4 4 2 0 Peroxisome biogenesis factor 1, N-terminal SnoaL_4 PF13577.6 EPE28079.1 - 1.2e-18 67.4 0.0 1.5e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Ribosomal_L18p PF00861.22 EPE28080.1 - 1 9.7 0.0 1 9.7 0.0 3.4 4 0 0 4 4 4 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Peptidase_C48 PF02902.19 EPE28081.1 - 7.3e-16 58.7 0.0 2.6e-15 56.9 0.0 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 EPE28081.1 - 0.041 13.9 0.2 0.11 12.5 0.0 1.8 2 0 0 2 2 2 0 Domian of unknown function (DUF4951) DUF3070 PF11270.8 EPE28081.1 - 0.06 13.6 0.1 0.23 11.7 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3070) Chromo PF00385.24 EPE28082.1 - 0.0034 17.2 1.3 0.007 16.2 1.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Pam17 PF08566.10 EPE28083.1 - 6.4e-68 227.8 0.0 8.3e-68 227.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Sel_put PF04328.13 EPE28083.1 - 0.35 10.9 2.7 0.46 10.6 0.1 2.4 3 0 0 3 3 3 0 Selenoprotein, putative ThiF PF00899.21 EPE28084.1 - 1.3e-57 194.9 0.0 1.9e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EPE28084.1 - 2.4e-10 40.9 0.0 6.9e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 EPE28084.1 - 0.1 12.7 0.9 1 9.4 0.0 2.9 3 1 1 4 4 4 0 Shikimate / quinate 5-dehydrogenase PspA_IM30 PF04012.12 EPE28084.1 - 0.39 10.3 2.1 0.61 9.6 2.1 1.3 1 0 0 1 1 1 0 PspA/IM30 family SLX9 PF15341.6 EPE28085.1 - 3.1e-30 105.2 2.1 3.1e-30 105.2 2.1 1.4 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 AP_endonuc_2 PF01261.24 EPE28086.1 - 1.1e-39 136.0 0.0 1.5e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Tmemb_9 PF05434.11 EPE28087.1 - 0.0018 18.2 0.1 0.0035 17.2 0.1 1.4 1 0 0 1 1 1 1 TMEM9 zf-CCHC_6 PF15288.6 EPE28088.1 - 0.12 12.2 1.5 0.17 11.8 1.1 1.4 1 1 0 1 1 1 0 Zinc knuckle ADH_N PF08240.12 EPE28089.1 - 4.7e-16 58.6 0.3 1.2e-15 57.4 0.3 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE28089.1 - 2.3e-06 27.6 0.1 1.1e-05 25.5 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase HI0933_like PF03486.14 EPE28089.1 - 0.003 16.3 0.0 0.0044 15.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EPE28089.1 - 0.051 12.9 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 EPE28089.1 - 0.094 12.2 0.0 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus HET PF06985.11 EPE28090.1 - 7.6e-29 100.9 0.2 1.3e-28 100.2 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RabGAP-TBC PF00566.18 EPE28094.1 - 0.066 12.9 0.3 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 Rab-GTPase-TBC domain Gloverin PF10793.9 EPE28094.1 - 0.082 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Gloverin-like protein DUF4199 PF13858.6 EPE28094.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DAAD PF18752.1 EPE28098.1 - 0.078 12.8 5.0 0.12 12.2 5.0 1.3 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase Pyr_redox_2 PF07992.14 EPE28099.1 - 1.4e-19 70.5 0.1 7.4e-18 64.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE28099.1 - 5.5e-15 55.4 0.2 1.8e-13 50.4 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EPE28099.1 - 5.9e-14 51.4 0.0 3.1e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EPE28099.1 - 1.3e-10 41.4 0.1 8e-08 32.4 0.0 3.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EPE28099.1 - 3.6e-07 30.3 0.4 1.3e-05 25.2 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EPE28099.1 - 5.2e-07 29.6 0.2 0.027 14.1 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 EPE28099.1 - 1.9e-06 27.3 0.3 2.2e-05 23.8 0.1 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 EPE28099.1 - 3.8e-06 26.5 0.0 0.00018 20.9 0.0 2.2 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EPE28099.1 - 0.00037 19.8 1.5 0.00045 19.5 0.0 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EPE28099.1 - 0.00043 19.1 0.0 0.079 11.6 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 EPE28099.1 - 0.0015 19.0 2.6 0.87 10.2 0.0 3.5 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EPE28099.1 - 0.0018 17.6 0.0 0.013 14.8 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain DUF3592 PF12158.8 EPE28099.1 - 0.011 15.8 0.2 0.067 13.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) Trp_halogenase PF04820.14 EPE28099.1 - 0.066 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase NACHT PF05729.12 EPE28101.1 - 2.3e-06 27.6 0.1 1.9e-05 24.7 0.1 2.3 1 1 0 1 1 1 1 NACHT domain DUF676 PF05057.14 EPE28101.1 - 1e-05 25.2 0.1 3.2e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 EPE28101.1 - 0.0051 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold RNA_helicase PF00910.22 EPE28101.1 - 0.0056 17.0 0.1 0.056 13.8 0.1 2.7 2 0 0 2 2 2 1 RNA helicase Abhydrolase_6 PF12697.7 EPE28101.1 - 0.021 15.4 0.0 0.064 13.8 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_16 PF13191.6 EPE28101.1 - 0.032 14.6 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EPE28101.1 - 0.035 14.4 0.0 0.14 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain PGAP1 PF07819.13 EPE28101.1 - 0.035 13.8 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Ploopntkinase3 PF18751.1 EPE28101.1 - 0.04 13.8 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 EPE28101.1 - 0.042 14.4 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EPE28101.1 - 0.044 13.9 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EPE28101.1 - 0.052 14.1 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 EPE28101.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 EPE28101.1 - 0.072 13.2 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EPE28101.1 - 0.085 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 EPE28101.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Septin NB-ARC PF00931.22 EPE28101.1 - 0.14 11.4 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 EPE28101.1 - 0.17 11.6 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EPE28101.1 - 0.18 11.5 0.0 0.45 10.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EPE28101.1 - 0.21 10.8 1.0 8.7 5.5 0.1 2.2 2 0 0 2 2 2 0 KAP family P-loop domain MFS_1 PF07690.16 EPE28102.1 - 4.6e-35 121.2 25.6 4.6e-35 121.2 25.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Caveolin PF01146.17 EPE28102.1 - 7.8 6.5 6.1 1.4 8.9 2.3 1.7 2 0 0 2 2 2 0 Caveolin Trep_Strep PF09605.10 EPE28103.1 - 0.1 12.6 0.7 0.1 12.6 0.7 1.6 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) CFEM PF05730.11 EPE28103.1 - 0.36 11.0 10.7 1.2 9.3 10.7 1.8 1 1 0 1 1 1 0 CFEM domain SprA-related PF12118.8 EPE28103.1 - 3.2 6.8 4.3 4.1 6.5 4.3 1.1 1 0 0 1 1 1 0 SprA-related family TMEM171 PF15471.6 EPE28105.1 - 2.2 7.2 5.7 5.9 5.8 5.7 1.7 1 0 0 1 1 1 0 Transmembrane protein family 171 eIF2A PF08662.11 EPE28107.1 - 1.8e-35 122.6 6.2 3.1e-34 118.5 0.3 3.9 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EPE28107.1 - 0.00013 21.7 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EPE28107.1 - 0.0074 17.1 1.3 1.3 10.0 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF4467 PF14729.6 EPE28107.1 - 0.021 15.2 0.3 0.4 11.1 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function with cystatin-like fold (DUF4467) Cpn60_TCP1 PF00118.24 EPE28108.1 - 2.1e-142 475.3 11.9 2.4e-142 475.1 11.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 EPE28108.1 - 0.022 14.9 0.1 0.049 13.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5442) CRM1_repeat PF18777.1 EPE28108.1 - 0.099 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Ribonuc_2-5A PF06479.12 EPE28109.1 - 2.5e-44 150.5 0.3 6.2e-44 149.2 0.2 1.8 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 EPE28109.1 - 7.8e-42 143.5 0.0 4.1e-31 108.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE28109.1 - 4.9e-22 78.4 0.0 1.1e-19 70.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPE28109.1 - 7.3e-05 21.7 0.0 0.00021 20.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EPE28109.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPE28109.1 - 0.075 12.9 0.3 0.36 10.7 0.2 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ada_Zn_binding PF02805.16 EPE28110.1 - 1.3e-27 95.6 2.0 2.5e-27 94.7 2.0 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 EPE28110.1 - 5.6e-08 32.7 0.0 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 EPE28110.1 - 0.00012 22.2 0.0 0.00023 21.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Suv3_N PF18114.1 EPE28110.1 - 0.018 15.2 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 Suv3 helical N-terminal domain HTH_23 PF13384.6 EPE28110.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Flavin_Reduct PF01613.18 EPE28111.1 - 2.9e-08 33.9 0.0 3.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 EPE28111.1 - 0.0054 16.5 0.0 0.011 15.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF447) Putative_PNPOx PF01243.20 EPE28111.1 - 0.083 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DUF3791 PF12668.7 EPE28111.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) Abhydrolase_1 PF00561.20 EPE28112.1 - 1.8e-11 44.2 0.1 5.9e-09 36.0 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE28112.1 - 0.019 14.3 0.0 0.035 13.4 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 SWIB PF02201.18 EPE28113.1 - 4.2e-30 103.4 0.2 8.2e-30 102.5 0.2 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 EPE28113.1 - 6.5e-12 45.2 0.4 1.6e-11 44.0 0.4 1.6 1 0 0 1 1 1 1 DEK C terminal domain SRP-alpha_N PF04086.13 EPE28113.1 - 1.3 8.9 14.6 1.6 8.6 14.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal zf-C3HC4_3 PF13920.6 EPE28114.1 - 8.9e-06 25.5 9.7 8.9e-06 25.5 9.7 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Phytoreo_S7 PF07236.11 EPE28114.1 - 0.22 9.8 0.1 0.34 9.2 0.1 1.2 1 0 0 1 1 1 0 Phytoreovirus S7 protein zf-C3HC4_2 PF13923.6 EPE28114.1 - 8.6 6.3 22.6 0.017 15.0 10.9 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Epimerase PF01370.21 EPE28115.1 - 2.9e-09 36.7 0.1 0.002 17.6 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPE28115.1 - 6.3e-09 36.0 0.6 1.2e-08 35.1 0.6 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPE28115.1 - 1.3e-06 28.2 0.1 2e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EPE28115.1 - 0.00012 22.5 0.1 0.00022 21.7 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EPE28115.1 - 0.0013 18.3 0.0 0.91 8.9 0.1 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPE28115.1 - 0.013 14.6 0.1 0.034 13.3 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein DapB_N PF01113.20 EPE28115.1 - 0.1 12.8 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NACHT PF05729.12 EPE28116.1 - 2.9e-08 33.8 0.0 7.2e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain SesA PF17107.5 EPE28116.1 - 7.9e-05 22.8 1.2 0.00021 21.4 1.2 1.8 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 EPE28116.1 - 0.014 15.7 0.0 0.093 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EPE28116.1 - 0.065 13.0 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EPE28116.1 - 0.068 13.7 2.6 0.1 13.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EPE28116.1 - 0.12 12.9 1.1 0.27 11.7 0.1 2.1 2 1 0 2 2 2 0 ABC transporter zf-MYND PF01753.18 EPE28118.1 - 2e-07 31.0 14.4 6.7e-07 29.3 14.5 1.9 1 1 0 1 1 1 1 MYND finger Yeast_MT PF11403.8 EPE28118.1 - 3.4 8.3 6.9 9 7.0 6.9 1.7 1 0 0 1 1 1 0 Yeast metallothionein RhoGAP PF00620.27 EPE28127.1 - 2.3e-28 98.9 0.0 4e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.12 EPE28128.1 - 3.8e-59 199.2 2.6 4.4e-59 199.0 2.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.9 EPE28129.1 - 7.8e-97 324.2 0.0 9.5e-97 323.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 DUF2791 PF10923.8 EPE28129.1 - 0.0029 16.5 0.2 0.022 13.6 0.0 2.1 2 0 0 2 2 2 1 P-loop Domain of unknown function (DUF2791) AAA_16 PF13191.6 EPE28129.1 - 0.048 14.0 0.0 0.14 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EPE28129.1 - 0.18 11.7 0.2 2.2 8.2 0.2 2.3 1 1 0 1 1 1 0 NACHT domain SesA PF17107.5 EPE28131.1 - 0.0068 16.6 4.4 0.18 12.0 0.1 3.7 1 1 1 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases 6PF2K PF01591.18 EPE28131.1 - 0.02 14.2 4.1 0.22 10.8 0.0 2.6 2 1 0 2 2 2 0 6-phosphofructo-2-kinase SBF PF01758.16 EPE28131.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Sodium Bile acid symporter family HeLo PF14479.6 EPE28131.1 - 0.26 11.1 0.0 0.26 11.1 0.0 3.8 2 1 0 3 3 3 0 Prion-inhibition and propagation DNApol3-delta_C PF09115.10 EPE28131.1 - 0.89 10.1 9.7 1.4 9.5 0.4 4.1 3 2 1 4 4 4 0 DNA polymerase III, delta subunit, C terminal adh_short PF00106.25 EPE28131.1 - 1.1 8.7 6.6 0.11 11.9 1.7 1.9 2 0 0 2 2 2 0 short chain dehydrogenase DUF948 PF06103.11 EPE28131.1 - 4.7 7.5 12.2 4.3 7.7 0.0 3.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 EPE28131.1 - 9.4 6.3 12.7 18 5.4 4.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DnaJ PF00226.31 EPE28133.1 - 9e-23 80.2 0.2 2.3e-22 78.9 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain Matrilin_ccoil PF10393.9 EPE28133.1 - 0.039 13.8 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Trm112p PF03966.16 EPE28133.1 - 0.063 13.9 1.7 0.23 12.0 0.0 2.8 3 1 0 3 3 3 0 Trm112p-like protein FYVE PF01363.21 EPE28133.1 - 0.39 10.9 4.8 0.77 9.9 4.8 1.5 1 0 0 1 1 1 0 FYVE zinc finger HypA PF01155.19 EPE28133.1 - 0.86 9.6 3.9 3.4 7.7 3.9 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MBOAT_2 PF13813.6 EPE28134.1 - 2e-16 60.0 5.3 5.5e-16 58.6 5.3 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family GD_AH_C PF04295.13 EPE28134.1 - 0.14 11.0 0.2 0.19 10.5 0.2 1.1 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus bZIP_1 PF00170.21 EPE28135.1 - 0.022 14.9 6.9 0.041 14.0 6.9 1.4 1 0 0 1 1 1 0 bZIP transcription factor Fungal_trans_2 PF11951.8 EPE28136.1 - 8.4e-18 64.3 1.1 1.8e-17 63.3 1.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 EPE28137.1 - 6.5e-22 77.8 2.0 6.5e-22 77.8 2.0 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EPE28137.1 - 2.7e-12 46.6 0.1 5.8e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like MutS_V PF00488.21 EPE28138.1 - 2.1e-71 239.8 0.2 5.1e-71 238.6 0.2 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EPE28138.1 - 5.1e-37 128.0 1.4 1.5e-36 126.5 1.4 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EPE28138.1 - 3.6e-28 98.1 0.0 7.8e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EPE28138.1 - 2e-06 28.1 0.0 6.5e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EPE28138.1 - 0.00012 22.3 0.0 0.00051 20.3 0.0 2.2 2 0 0 2 2 2 1 MutS family domain IV DUF4911 PF16256.5 EPE28138.1 - 0.018 15.0 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) DUF3416 PF11896.8 EPE28138.1 - 0.022 15.0 0.1 0.071 13.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) Glycoprotein_G PF00802.19 EPE28138.1 - 7.7 5.8 8.9 15 4.8 8.9 1.4 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G zf-SCNM1 PF15803.5 EPE28139.1 - 0.056 13.1 3.2 0.15 11.7 3.2 1.8 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 zf-C2H2_jaz PF12171.8 EPE28139.1 - 0.2 12.0 1.5 0.57 10.5 1.5 1.9 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EPE28139.1 - 0.56 10.8 2.2 1.4 9.5 2.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Prenyltrans PF00432.21 EPE28140.1 - 1.5e-56 187.8 11.0 1.9e-12 46.7 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EPE28140.1 - 0.00037 19.7 0.0 0.88 8.6 0.0 3.5 2 1 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EPE28140.1 - 0.084 11.9 0.5 8.7 5.3 0.1 2.9 1 1 0 2 2 2 0 Squalene-hopene cyclase C-terminal domain AIG2_2 PF13772.6 EPE28141.1 - 4.6e-06 26.9 0.1 1.9e-05 24.9 0.1 2.0 1 1 0 1 1 1 1 AIG2-like family Amidoligase_2 PF12224.8 EPE28142.1 - 3.8e-24 85.7 0.0 5.6e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 Putative amidoligase enzyme Tub_N PF16322.5 EPE28144.1 - 0.0016 18.9 1.6 0.0021 18.5 1.6 1.2 1 0 0 1 1 1 1 Tubby N-terminal BUD22 PF09073.10 EPE28144.1 - 2.1 7.6 6.8 3 7.1 6.8 1.1 1 0 0 1 1 1 0 BUD22 Astro_capsid_p PF12226.8 EPE28144.1 - 7.7 5.6 10.7 11 5.1 10.7 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein HLH PF00010.26 EPE28146.1 - 2.2e-07 30.7 0.6 5.8e-07 29.4 0.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain JAKMIP_CC3 PF16034.5 EPE28146.1 - 0.0015 18.5 7.7 0.0016 18.4 6.7 1.4 1 1 0 1 1 1 1 JAKMIP CC3 domain bZIP_2 PF07716.15 EPE28146.1 - 0.19 11.8 6.1 0.083 13.0 3.2 1.9 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 EPE28146.1 - 4.3 7.2 6.5 0.79 9.5 1.8 2.1 2 0 0 2 2 2 0 Septum formation initiator Cu-oxidase_2 PF07731.14 EPE28147.1 - 3.4e-25 88.4 1.3 7.5e-23 80.8 0.8 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EPE28147.1 - 9.7e-21 74.0 0.6 2e-20 73.0 0.1 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EPE28147.1 - 8.9e-09 35.7 0.0 3.6e-06 27.2 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase peroxidase PF00141.23 EPE28148.1 - 4.5e-26 92.0 0.0 7.1e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 EPE28148.1 - 0.0051 16.7 0.0 0.017 15.0 0.0 1.9 1 0 0 1 1 1 1 Fungal peroxidase extension region Ribosomal_S28e PF01200.18 EPE28149.1 - 3.5e-31 107.0 2.3 3.9e-31 106.8 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.18 EPE28150.1 - 3.9e-56 189.4 0.3 7.4e-56 188.5 0.1 1.6 2 0 0 2 2 2 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EPE28150.1 - 6.4e-30 103.1 0.5 1.1e-29 102.3 0.5 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 EPE28150.1 - 0.069 13.1 0.0 1.4 8.9 0.0 2.3 2 0 0 2 2 2 0 NMT1/THI5 like KDZ PF18758.1 EPE28150.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase Cytokin_check_N PF10407.9 EPE28152.1 - 0.0034 17.3 0.0 0.0069 16.3 0.0 1.5 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Lipase_GDSL_2 PF13472.6 EPE28153.1 - 7.9e-17 62.2 1.3 1.3e-16 61.5 1.3 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE28153.1 - 4e-09 36.8 0.0 6.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Peroxidase_2 PF01328.17 EPE28155.1 - 0.069 13.7 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Peroxidase, family 2 Fungal_trans_2 PF11951.8 EPE28156.1 - 0.00019 20.3 0.1 0.0003 19.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE28156.1 - 0.00099 19.2 4.6 0.0017 18.5 4.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MARVEL PF01284.23 EPE28157.1 - 5.6e-06 26.4 20.9 8.2e-06 25.9 20.1 1.6 1 1 1 2 2 2 2 Membrane-associating domain Tetraspanin PF00335.20 EPE28157.1 - 6.7 6.4 11.9 25 4.5 12.4 1.6 1 1 1 2 2 2 0 Tetraspanin family Glyco_transf_28 PF03033.20 EPE28158.1 - 4.9e-21 75.2 0.0 1.2e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EPE28158.1 - 1.2e-07 30.9 0.0 2.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 EPE28158.1 - 0.00064 19.5 0.6 0.0016 18.3 0.4 1.6 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 EPE28158.1 - 0.001 19.4 0.5 0.011 16.0 0.1 2.5 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain FAD_binding_4 PF01565.23 EPE28159.1 - 2.2e-22 79.3 1.3 5.9e-22 77.9 1.3 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE28159.1 - 2.3e-07 30.8 0.8 4.6e-07 29.8 0.8 1.5 1 0 0 1 1 1 1 Berberine and berberine like Fijivirus_P9-2 PF06837.11 EPE28160.1 - 3.9 6.9 6.4 7 6.0 6.4 1.3 1 0 0 1 1 1 0 Fijivirus P9-2 protein p450 PF00067.22 EPE28162.1 - 6.9e-37 127.3 0.0 9e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3328 PF11807.8 EPE28163.1 - 1.5e-24 87.0 0.0 1.9e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Pex2_Pex12 PF04757.14 EPE28164.1 - 1.8e-40 138.9 10.0 2.2e-40 138.6 10.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 EPE28164.1 - 4.7e-11 42.3 7.5 8e-11 41.6 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE28164.1 - 5.5e-11 42.6 8.1 9.2e-11 41.9 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EPE28164.1 - 3.6e-10 39.5 5.5 5.4e-10 39.0 5.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE28164.1 - 2.1e-09 37.1 5.4 3.6e-09 36.3 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE28164.1 - 2.5e-07 30.6 5.6 5.6e-07 29.5 5.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EPE28164.1 - 5.2e-07 29.4 6.2 8.1e-07 28.8 6.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EPE28164.1 - 1.2e-06 28.6 7.6 2.1e-06 27.8 7.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EPE28164.1 - 2.4e-06 27.7 8.3 5.7e-06 26.5 8.3 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EPE28164.1 - 6e-06 26.1 4.5 1e-05 25.4 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 EPE28164.1 - 0.0017 18.4 5.6 0.0029 17.7 5.6 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 EPE28164.1 - 0.0021 17.9 2.3 0.0042 16.9 2.3 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EPE28164.1 - 0.12 12.2 6.9 0.28 11.0 6.8 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EPE28164.1 - 0.38 10.5 3.6 0.85 9.4 3.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger EXS PF03124.14 EPE28165.1 - 2.1e-111 372.4 9.1 2.4e-111 372.2 9.1 1.0 1 0 0 1 1 1 1 EXS family ABC_tran PF00005.27 EPE28166.1 - 3.5e-41 140.9 0.0 1.1e-22 81.0 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPE28166.1 - 6.6e-34 117.8 23.1 1.9e-25 90.1 12.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region RsgA_GTPase PF03193.16 EPE28166.1 - 1.7e-06 28.1 0.2 0.069 13.1 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EPE28166.1 - 2.5e-06 27.1 5.9 0.0021 17.8 0.7 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EPE28166.1 - 6.4e-06 26.5 1.2 0.03 14.6 0.0 3.2 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.19 EPE28166.1 - 7e-06 25.6 0.3 4.4 6.7 0.0 4.3 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EPE28166.1 - 3.1e-05 24.0 0.1 0.3 11.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EPE28166.1 - 3.3e-05 23.9 0.1 1.3 8.8 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 EPE28166.1 - 5.1e-05 23.4 0.4 0.27 11.3 0.0 2.4 2 0 0 2 2 2 2 Dynamin family T2SSE PF00437.20 EPE28166.1 - 0.00016 20.8 1.1 0.35 9.9 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EPE28166.1 - 0.00022 20.6 1.2 0.52 9.6 0.1 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family NACHT PF05729.12 EPE28166.1 - 0.00066 19.6 0.9 0.058 13.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EPE28166.1 - 0.0045 17.4 0.2 1.1 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EPE28166.1 - 0.0065 16.6 0.1 0.27 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EPE28166.1 - 0.0067 16.0 1.0 0.81 9.2 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 EPE28166.1 - 0.016 14.8 1.3 1.8 8.1 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EPE28166.1 - 0.018 15.5 6.8 0.73 10.3 0.9 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EPE28166.1 - 0.29 10.8 0.9 5.6 6.6 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EPE28166.1 - 0.3 10.8 3.5 2.9 7.5 0.2 2.2 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 EPE28166.1 - 0.3 11.0 0.9 2.8 7.8 0.0 2.4 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 EPE28166.1 - 0.49 10.5 6.1 1.8 8.6 1.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Phage_holin_3_6 PF07332.11 EPE28166.1 - 1.5 8.8 12.9 1.8 8.6 0.6 4.2 4 0 0 4 4 3 0 Putative Actinobacterial Holin-X, holin superfamily III TsaE PF02367.17 EPE28166.1 - 1.8 8.6 3.3 3.6 7.6 0.1 2.7 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 EPE28166.1 - 3.4 6.5 4.8 8.2 5.2 0.4 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 EPE28166.1 - 3.5 7.2 5.7 4.6 6.8 0.8 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CTP_transf_like PF01467.26 EPE28167.1 - 0.00056 20.1 0.0 0.00098 19.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like Phage_T7_Capsid PF05396.11 EPE28167.1 - 0.065 13.6 0.4 0.22 11.9 0.1 1.9 2 0 0 2 2 2 0 Phage T7 capsid assembly protein Atg29_N PF18388.1 EPE28167.1 - 0.067 13.0 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Atg29 N-terminal domain BTG PF07742.12 EPE28167.1 - 0.12 12.2 0.1 0.45 10.4 0.1 1.7 1 1 0 1 1 1 0 BTG family Prot_ATP_OB_N PF17758.1 EPE28168.1 - 0.2 11.3 0.0 0.47 10.1 0.0 1.6 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain CENP-X PF09415.10 EPE28169.1 - 0.19 12.1 1.4 0.39 11.1 0.0 2.1 3 0 0 3 3 3 0 CENP-S associating Centromere protein X E1_UFD PF09358.10 EPE28170.1 - 0.057 14.1 0.1 0.12 13.1 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin fold domain YjcB PF15940.5 EPE28170.1 - 0.079 13.1 0.5 0.079 13.1 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function GFA PF04828.14 EPE28171.1 - 1.1e-05 25.7 1.8 1.1e-05 25.7 1.8 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme SOG2 PF10428.9 EPE28172.1 - 0.38 9.9 16.3 0.66 9.1 16.3 1.3 1 1 0 1 1 1 0 RAM signalling pathway protein Amidohydro_1 PF01979.20 EPE28173.1 - 1.2e-43 149.8 0.0 1.4e-43 149.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPE28173.1 - 2.7e-20 73.3 0.4 2.2e-14 53.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Glycoamylase PF10091.9 EPE28173.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative glucoamylase Zn_clus PF00172.18 EPE28174.1 - 1.8e-05 24.7 7.4 5e-05 23.3 7.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE28174.1 - 0.00055 19.1 3.0 0.00055 19.1 3.0 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain SKA2 PF16740.5 EPE28174.1 - 0.012 15.3 0.8 0.15 11.9 0.9 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF4175 PF13779.6 EPE28174.1 - 0.065 11.1 3.7 0.092 10.6 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Fungal_trans PF04082.18 EPE28175.1 - 2.4e-24 85.8 0.2 4.9e-24 84.8 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE28175.1 - 8.1e-06 25.9 9.4 8.1e-06 25.9 9.4 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPE28176.1 - 2.2e-32 112.4 24.1 2.2e-32 112.4 24.1 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE28176.1 - 0.00014 20.5 1.1 0.0002 20.0 1.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gpr1_Fun34_YaaH PF01184.19 EPE28177.1 - 2.3e-87 291.9 23.6 2.7e-87 291.7 23.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family TcpE PF12648.7 EPE28177.1 - 1.5 9.4 5.5 1.1 9.8 3.4 1.8 2 0 0 2 2 2 0 TcpE family Velvet PF11754.8 EPE28178.1 - 1.5e-91 306.8 0.0 2.7e-91 305.9 0.0 1.4 1 0 0 1 1 1 1 Velvet factor Fer2_3 PF13085.6 EPE28179.1 - 1.6e-31 108.5 0.0 2.7e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EPE28179.1 - 4.5e-09 36.7 7.1 4.5e-09 36.7 7.1 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EPE28179.1 - 5.6e-07 29.9 9.5 5.6e-07 29.9 9.5 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EPE28179.1 - 1.9e-06 27.8 4.4 1.9e-06 27.8 4.4 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EPE28179.1 - 0.011 15.6 0.5 0.011 15.6 0.5 2.5 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 EPE28179.1 - 0.015 15.4 2.8 0.26 11.5 0.2 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 EPE28179.1 - 0.022 15.3 8.7 0.022 15.3 8.7 2.6 1 1 2 3 3 3 0 4Fe-4S dicluster domain Hydrolase_4 PF12146.8 EPE28180.1 - 2.5e-15 56.4 0.0 8.4e-11 41.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE28180.1 - 5.3e-10 39.4 0.1 3.4e-07 30.2 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE28180.1 - 4.6e-06 27.4 0.0 9.9e-06 26.3 0.0 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.12 EPE28180.1 - 2.5e-05 23.1 0.3 0.37 9.4 0.1 3.0 2 1 1 3 3 3 3 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 EPE28180.1 - 3.2e-05 23.7 0.0 0.00013 21.7 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EPE28180.1 - 9e-05 22.4 0.3 0.02 14.7 0.0 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EPE28180.1 - 0.00048 19.7 0.0 0.0014 18.2 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.12 EPE28180.1 - 0.0013 17.8 0.0 0.0018 17.3 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_3 PF07859.13 EPE28180.1 - 0.0023 17.8 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 EPE28180.1 - 0.0024 17.8 0.0 0.024 14.6 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 EPE28180.1 - 0.0037 16.9 0.0 1.1 8.8 0.0 2.7 2 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 EPE28180.1 - 0.0083 15.7 0.0 0.67 9.5 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.20 EPE28180.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 EPE28180.1 - 0.21 11.7 0.0 0.44 10.6 0.0 1.5 2 0 0 2 2 2 0 Thioesterase domain zf-LYAR PF08790.11 EPE28181.1 - 1.4e-14 53.7 2.6 1.4e-14 53.7 2.6 2.0 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Clr2 PF10383.9 EPE28181.1 - 0.9 10.3 4.0 6.5 7.5 1.1 2.9 2 1 0 2 2 2 0 Transcription-silencing protein Clr2 R3H PF01424.22 EPE28182.1 - 2.9e-16 59.2 0.5 5e-16 58.4 0.5 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 EPE28182.1 - 2.3e-11 43.5 64.8 1.6e-05 24.8 12.4 12.2 11 1 1 12 12 12 6 NF-X1 type zinc finger Kelch_5 PF13854.6 EPE28183.1 - 1.2e-08 34.8 1.9 0.0005 20.0 0.0 4.1 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 EPE28183.1 - 1e-05 25.0 0.7 0.047 13.3 0.1 3.8 3 0 0 3 3 3 2 Kelch motif Mid2 PF04478.12 EPE28183.1 - 0.021 14.7 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor VSP PF03302.13 EPE28183.1 - 0.077 11.8 0.1 0.14 11.0 0.1 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein Kelch_2 PF07646.15 EPE28183.1 - 1 9.4 5.4 15 5.8 0.0 4.2 4 0 0 4 4 4 0 Kelch motif DUF3602 PF12223.8 EPE28184.1 - 1.2e-15 57.8 13.1 8.5e-11 42.3 3.8 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) GH115_C PF17829.1 EPE28184.1 - 0.051 13.4 0.4 0.093 12.6 0.4 1.5 1 1 0 1 1 1 0 Gylcosyl hydrolase family 115 C-terminal domain RhoGEF PF00621.20 EPE28185.1 - 1.9e-27 96.7 0.1 4.4e-27 95.5 0.0 1.7 2 0 0 2 2 2 1 RhoGEF domain Telomerase_RBD PF12009.8 EPE28186.1 - 2.6e-48 163.5 3.9 3.1e-48 163.3 2.3 2.0 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 EPE28186.1 - 4.9e-15 55.7 0.0 2.5e-10 40.3 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) TERT_thumb PF17984.1 EPE28187.1 - 0.026 14.4 1.9 0.043 13.7 1.9 1.4 1 1 0 1 1 1 0 Telomerase reverse transcriptase thumb DNA binding domain IL32 PF15225.6 EPE28187.1 - 0.1 13.0 0.3 0.18 12.1 0.3 1.4 1 0 0 1 1 1 0 Interleukin 32 RabGAP-TBC PF00566.18 EPE28188.1 - 3.7e-34 118.3 0.0 6e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 EPE28188.1 - 4.5e-08 31.8 0.7 8.1e-08 31.0 0.7 1.3 1 0 0 1 1 1 1 SBE2, cell-wall formation DUF3328 PF11807.8 EPE28189.1 - 1.1e-15 58.0 0.4 2e-15 57.1 0.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Vac7 PF12751.7 EPE28189.1 - 0.031 13.7 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DUF3399 PF11879.8 EPE28189.1 - 7 7.0 7.1 8.5 6.8 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3399) DUF3328 PF11807.8 EPE28190.1 - 5.6e-54 183.2 0.0 6.8e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.16 EPE28192.1 - 3.6e-35 121.5 25.7 5.2e-35 121.0 25.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EPE28192.1 - 0.0095 15.7 1.4 0.027 14.2 1.4 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Ceramidase PF05875.12 EPE28192.1 - 0.064 12.7 3.4 0.32 10.4 2.4 2.4 1 1 1 2 2 2 0 Ceramidase CoA_trans PF01144.23 EPE28194.1 - 5.8e-100 333.1 6.7 2.5e-61 206.9 1.4 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EPE28194.1 - 0.033 14.1 0.1 0.071 13.1 0.1 1.5 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain LPMO_10 PF03067.15 EPE28195.1 - 7.7e-05 23.4 0.0 0.00017 22.3 0.0 1.6 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading MFS_1 PF07690.16 EPE28196.1 - 7e-33 114.0 31.3 4.5e-31 108.1 32.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.12 EPE28196.1 - 0.0031 17.2 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF697) adh_short PF00106.25 EPE28197.1 - 4.2e-39 134.0 0.4 5.7e-39 133.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE28197.1 - 1.4e-35 122.9 0.3 1.6e-35 122.7 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE28197.1 - 6.7e-10 39.2 0.6 9e-10 38.7 0.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE28197.1 - 0.00062 19.3 0.3 0.0015 18.0 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.16 EPE28197.1 - 0.015 16.0 0.4 0.024 15.3 0.4 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GDP_Man_Dehyd PF16363.5 EPE28197.1 - 0.033 13.6 0.2 0.059 12.8 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EPE28197.1 - 0.033 13.3 0.3 0.045 12.9 0.3 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EPE28197.1 - 0.039 13.9 0.3 0.08 12.8 0.3 1.5 1 1 0 1 1 1 0 NAD(P)H-binding Ldh_1_N PF00056.23 EPE28197.1 - 0.05 13.7 0.1 0.09 12.9 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain MFS_1 PF07690.16 EPE28198.1 - 5.5e-33 114.3 50.4 5.7e-33 114.3 45.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE28198.1 - 6.4e-15 55.0 4.9 6.4e-15 55.0 4.9 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Hum_adeno_E3A PF05393.11 EPE28198.1 - 0.13 12.2 0.0 0.47 10.5 0.0 2.0 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein p450 PF00067.22 EPE28199.1 - 2.1e-51 175.1 0.0 2.8e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 EPE28200.1 - 8.9e-21 74.1 0.0 1.3e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_2 PF00891.18 EPE28201.1 - 9e-09 34.9 0.0 1.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain HTH_IclR PF09339.10 EPE28201.1 - 0.099 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.6 EPE28201.1 - 0.17 11.4 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding NmrA PF05368.13 EPE28203.1 - 3e-32 112.1 0.0 3.6e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE28203.1 - 1.9e-18 67.0 0.0 2.9e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE28203.1 - 8.2e-05 22.2 0.0 0.00025 20.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ComA PF02679.15 EPE28203.1 - 0.029 13.9 0.1 6.7 6.1 0.0 2.9 3 0 0 3 3 3 0 (2R)-phospho-3-sulfolactate synthase (ComA) Glyco_tran_WbsX PF14307.6 EPE28203.1 - 0.095 12.1 0.0 0.22 10.9 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase WbsX p450 PF00067.22 EPE28204.1 - 3.8e-23 82.0 0.0 9.6e-23 80.6 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 Methyltransf_2 PF00891.18 EPE28205.1 - 9e-17 61.1 0.0 1.2e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EPE28205.1 - 0.035 14.1 0.2 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Dimerisation domain TrmB PF01978.19 EPE28205.1 - 0.057 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Methyltransf_2 PF00891.18 EPE28206.1 - 2.9e-24 85.5 0.0 4.4e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EPE28206.1 - 0.047 14.4 0.0 0.15 12.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.28 EPE28207.1 - 1.7e-55 188.3 0.0 2.4e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 EPE28207.1 - 4e-27 95.8 0.0 4.7e-25 89.0 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 EPE28207.1 - 1.3e-11 44.6 0.0 3.5e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 EPE28207.1 - 0.0019 18.8 0.6 0.0044 17.6 0.6 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE28207.1 - 0.016 14.8 0.2 0.032 13.9 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold GH3 PF03321.13 EPE28207.1 - 0.022 13.6 0.0 3.1 6.5 0.0 2.4 2 0 0 2 2 2 0 GH3 auxin-responsive promoter PE-PPE PF08237.11 EPE28207.1 - 0.18 11.3 0.0 1.4 8.4 0.0 2.0 2 0 0 2 2 2 0 PE-PPE domain Aminotran_1_2 PF00155.21 EPE28208.1 - 2.7e-44 151.8 0.0 3.4e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EPE28208.1 - 0.0022 17.3 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase BNR_2 PF13088.6 EPE28209.1 - 0.0025 17.1 0.0 1.4 8.1 0.0 2.3 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 EPE28209.1 - 1.5 9.1 6.3 14 6.1 0.0 4.6 5 0 0 5 5 5 0 BNR/Asp-box repeat 2OG-FeII_Oxy_3 PF13640.6 EPE28210.1 - 1e-09 39.2 0.0 2.5e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 EPE28211.1 - 3.6e-88 296.0 0.0 1.2e-87 294.3 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EPE28211.1 - 4.7e-53 180.0 0.0 8.8e-53 179.1 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EPE28211.1 - 1.3e-15 57.6 0.0 2.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE28211.1 - 1.8e-09 37.0 0.0 4e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EPE28211.1 - 8.7e-09 34.9 0.0 4.7e-08 32.5 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EPE28211.1 - 7.2e-08 32.2 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EPE28211.1 - 3.8e-07 30.2 0.1 0.0076 16.2 0.1 2.3 2 0 0 2 2 2 2 NAD(P)H-binding PP-binding PF00550.25 EPE28211.1 - 8.7e-05 22.8 0.0 0.0002 21.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPE28211.1 - 0.0011 19.9 0.0 0.0025 18.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 EPE28211.1 - 0.0076 15.4 0.0 0.028 13.5 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EPE28211.1 - 0.019 14.9 0.2 0.057 13.3 0.2 1.8 1 1 0 1 1 1 0 KR domain tRNA-synt_1b PF00579.25 EPE28212.1 - 4.3e-53 180.5 0.0 5.6e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HIT PF01230.23 EPE28213.1 - 2.3e-24 86.0 0.0 3.3e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EPE28213.1 - 1.1e-05 25.9 0.1 1.7e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 EPE28213.1 - 0.15 11.8 0.2 0.3 10.8 0.0 1.5 2 0 0 2 2 2 0 Galactose-1-phosphate uridyl transferase, C-terminal domain APH PF01636.23 EPE28215.1 - 1.9e-19 70.5 0.1 2.8e-19 70.0 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE28215.1 - 3.3e-13 49.7 0.0 7.2e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EPE28215.1 - 0.0018 17.7 0.2 0.0027 17.1 0.2 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase HAD_SAK_2 PF18143.1 EPE28215.1 - 0.028 14.7 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins Kdo PF06293.14 EPE28215.1 - 0.036 13.4 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PI3_PI4_kinase PF00454.27 EPE28215.1 - 0.14 12.0 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Transferase PF02458.15 EPE28217.1 - 3.9e-36 124.6 0.0 4.7e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Transferase family U3_snoRNA_assoc PF08297.11 EPE28219.1 - 0.0076 16.9 3.7 0.014 16.1 3.7 1.4 1 0 0 1 1 1 1 U3 snoRNA associated TypeIII_RM_meth PF12564.8 EPE28220.1 - 0.051 13.7 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit HnRNP_M PF11532.8 EPE28220.1 - 0.063 13.5 0.2 0.11 12.7 0.2 1.3 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M p450 PF00067.22 EPE28221.1 - 2.2e-48 165.2 0.1 3e-48 164.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pex26 PF07163.12 EPE28222.1 - 0.0045 16.3 0.4 0.0066 15.8 0.4 1.1 1 0 0 1 1 1 1 Pex26 protein DUF4660 PF15559.6 EPE28222.1 - 0.033 14.5 0.1 0.033 14.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) Aldo_ket_red PF00248.21 EPE28223.1 - 7.9e-40 136.9 0.0 1.1e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family AAA PF00004.29 EPE28224.1 - 3e-15 56.8 0.0 1e-14 55.1 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EPE28224.1 - 0.0012 18.8 0.0 0.0034 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPE28224.1 - 0.048 13.9 0.2 0.048 13.9 0.2 2.9 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.6 EPE28224.1 - 0.18 11.6 0.0 0.18 11.6 0.0 4.1 2 1 0 2 2 2 0 AAA domain Peptidase_C14 PF00656.22 EPE28225.1 - 3.7e-09 36.9 0.0 1.5e-08 34.9 0.0 1.7 1 1 1 2 2 2 1 Caspase domain Raptor_N PF14538.6 EPE28225.1 - 0.022 14.7 0.1 0.06 13.3 0.1 1.7 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF452 PF04301.13 EPE28225.1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF452) DUF2207 PF09972.9 EPE28227.1 - 0.012 14.4 0.1 0.014 14.1 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cyt_bd_oxida_II PF02322.15 EPE28227.1 - 0.012 15.0 2.0 0.016 14.6 2.0 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II DUF983 PF06170.12 EPE28227.1 - 0.26 11.7 3.2 0.51 10.8 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF983) YqhR PF11085.8 EPE28227.1 - 0.3 11.0 3.7 0.46 10.4 3.7 1.2 1 0 0 1 1 1 0 Conserved membrane protein YqhR DUF1700 PF08006.11 EPE28227.1 - 1.8 8.1 7.7 0.095 12.2 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Syndecan PF01034.20 EPE28227.1 - 2.9 7.9 6.2 2 8.4 3.2 2.4 1 1 0 1 1 1 0 Syndecan domain S_4TM PF18159.1 EPE28227.1 - 3.1 7.0 9.8 0.066 12.5 1.9 2.1 2 1 0 2 2 2 0 SMODS-associating 4TM effector domain Ldh_1_C PF02866.18 EPE28228.1 - 1.4e-46 158.4 0.1 3.9e-46 157.0 0.1 1.7 3 0 0 3 3 3 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EPE28228.1 - 1.5e-43 148.3 0.0 9e-43 145.8 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EPE28228.1 - 0.0015 17.6 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EPE28228.1 - 0.15 12.5 0.4 0.71 10.3 0.0 2.3 2 1 1 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain Pex14_N PF04695.13 EPE28230.1 - 0.00053 20.7 0.3 0.00082 20.1 0.3 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3400 PF11880.8 EPE28232.1 - 0.099 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) Rad60-SLD_2 PF13881.6 EPE28235.1 - 5.1e-09 36.2 0.0 2.4e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EPE28235.1 - 0.0039 17.7 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EPE28235.1 - 0.079 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Med13_C PF06333.12 EPE28235.1 - 2.5 7.3 10.9 3.7 6.7 10.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain UMP1 PF05348.11 EPE28236.1 - 5.3e-41 139.5 0.0 6.3e-41 139.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 ABC_tran PF00005.27 EPE28237.1 - 1e-29 103.8 0.0 5.8e-16 59.3 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EPE28237.1 - 6.8e-13 49.1 9.4 0.00076 19.4 0.3 3.8 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EPE28237.1 - 1.8e-08 35.2 0.7 0.0081 16.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EPE28237.1 - 3.2e-07 30.0 0.1 0.0045 16.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 EPE28237.1 - 6.2e-06 26.4 0.1 0.0053 17.0 0.1 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 EPE28237.1 - 8e-06 26.3 0.0 0.025 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EPE28237.1 - 1.4e-05 25.4 0.1 0.11 12.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 EPE28237.1 - 2.9e-05 24.0 0.0 0.088 12.7 0.1 3.1 3 0 0 3 3 3 2 NACHT domain SMC_N PF02463.19 EPE28237.1 - 6.8e-05 22.4 0.1 0.062 12.7 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 EPE28237.1 - 0.00014 21.7 0.1 0.42 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EPE28237.1 - 0.00038 20.6 0.2 0.12 12.5 0.1 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_18 PF13238.6 EPE28237.1 - 0.0008 20.0 0.0 0.45 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EPE28237.1 - 0.00087 19.5 0.1 0.66 10.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EPE28237.1 - 0.002 17.8 0.1 0.55 9.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 EPE28237.1 - 0.0021 17.9 0.4 0.25 11.1 0.1 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA PF00004.29 EPE28237.1 - 0.0027 18.2 0.5 2.3 8.6 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EPE28237.1 - 0.0029 17.8 0.3 1.6 9.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EPE28237.1 - 0.0039 17.1 0.0 0.97 9.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 EPE28237.1 - 0.0047 16.5 0.1 1.9 8.0 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 EPE28237.1 - 0.0054 15.8 0.0 0.71 8.9 0.0 2.6 3 0 0 3 3 2 1 Type II/IV secretion system protein NB-ARC PF00931.22 EPE28237.1 - 0.0065 15.7 0.1 2.3 7.4 0.0 2.8 2 1 0 2 2 2 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 EPE28237.1 - 0.0087 15.4 0.1 0.086 12.2 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATPase_2 PF01637.18 EPE28237.1 - 0.009 15.9 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_15 PF13175.6 EPE28237.1 - 0.0094 15.7 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 EPE28237.1 - 0.01 15.9 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 EPE28237.1 - 0.015 15.3 0.2 3.8 7.5 0.1 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EPE28237.1 - 0.015 15.7 0.2 6.3 7.2 0.1 2.7 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 EPE28237.1 - 0.017 15.0 1.8 1.2 9.0 0.1 2.9 3 0 0 3 3 3 0 NTPase Pox_A32 PF04665.12 EPE28237.1 - 0.028 13.9 0.0 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_19 PF13245.6 EPE28237.1 - 0.037 14.4 0.0 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EPE28237.1 - 0.063 12.9 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.14 EPE28237.1 - 0.088 12.7 0.1 8.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.6 EPE28237.1 - 0.11 11.1 0.1 0.37 9.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EPE28237.1 - 0.13 12.0 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 EPE28237.1 - 0.14 12.6 0.2 23 5.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EPE28237.1 - 0.16 11.7 0.1 2.2 8.0 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 EPE28237.1 - 0.21 11.6 0.0 30 4.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 EPE28238.1 - 1e-24 87.2 29.3 1.3e-24 86.8 29.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Cir_N PF10197.9 EPE28238.1 - 0.47 10.7 3.7 1.2 9.4 3.7 1.6 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR RTA1 PF04479.13 EPE28240.1 - 3.6e-53 180.2 9.9 5.3e-53 179.7 9.9 1.2 1 0 0 1 1 1 1 RTA1 like protein ABC_tran PF00005.27 EPE28241.1 - 1.3e-46 158.5 0.2 1.1e-22 81.0 0.0 4.4 3 2 0 3 3 2 2 ABC transporter 4HB PF17947.1 EPE28241.1 - 1.8e-29 101.6 1.1 6.6e-29 99.8 0.0 2.6 2 1 0 2 2 2 1 Four helical bundle domain AAA_21 PF13304.6 EPE28241.1 - 5e-18 65.9 0.3 0.0021 17.9 0.0 5.1 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPE28241.1 - 2.1e-17 63.3 0.0 2.3e-05 23.9 0.0 3.7 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EPE28241.1 - 5e-09 36.9 11.6 5e-05 23.9 0.1 3.7 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 EPE28241.1 - 6.8e-09 35.3 0.0 0.0048 16.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EPE28241.1 - 9.5e-08 32.1 0.0 0.0014 18.6 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EPE28241.1 - 1.5e-07 31.4 0.0 0.0012 18.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 EPE28241.1 - 1.9e-07 31.3 0.1 4.5e-05 23.6 0.0 2.9 2 1 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 EPE28241.1 - 2.5e-07 31.0 0.1 0.0039 17.5 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_28 PF13521.6 EPE28241.1 - 9.6e-07 29.2 0.1 0.019 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EPE28241.1 - 4.7e-06 27.2 0.1 0.15 12.6 0.0 3.3 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 EPE28241.1 - 4.7e-05 23.7 0.0 0.55 10.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.6 EPE28241.1 - 5.4e-05 23.6 0.8 0.48 10.8 0.1 3.8 3 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 EPE28241.1 - 6.8e-05 23.3 0.1 0.47 10.9 0.1 4.2 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EPE28241.1 - 6.9e-05 23.0 0.0 0.46 10.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 EPE28241.1 - 7.5e-05 21.8 0.1 0.37 9.7 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 EPE28241.1 - 0.00013 21.8 6.2 0.055 13.2 0.0 4.0 4 1 0 5 5 4 2 AAA ATPase domain AAA_27 PF13514.6 EPE28241.1 - 0.0002 21.0 0.0 0.14 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EPE28241.1 - 0.00036 20.3 0.0 2.3 7.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 EPE28241.1 - 0.00056 19.7 0.3 1.2 8.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EPE28241.1 - 0.00073 19.5 0.0 0.19 11.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.9 EPE28241.1 - 0.00094 18.9 0.0 0.81 9.4 0.0 3.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 EPE28241.1 - 0.0011 19.0 0.1 3.7 7.6 0.0 3.6 4 0 0 4 4 4 0 AAA domain G-alpha PF00503.20 EPE28241.1 - 0.0021 17.3 0.1 2.6 7.1 0.0 2.8 3 0 0 3 3 3 2 G-protein alpha subunit ATPase_2 PF01637.18 EPE28241.1 - 0.0027 17.7 0.2 1.8 8.4 0.0 3.6 4 0 0 4 4 3 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 EPE28241.1 - 0.0033 17.4 0.0 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain cobW PF02492.19 EPE28241.1 - 0.0037 16.9 0.0 2.8 7.5 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EPE28241.1 - 0.005 16.1 0.1 0.32 10.1 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Roc PF08477.13 EPE28241.1 - 0.0057 16.9 0.2 10 6.4 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 EPE28241.1 - 0.0057 16.8 2.3 1.1 9.4 0.1 3.3 3 0 0 3 3 2 1 Helicase HerA, central domain SbcCD_C PF13558.6 EPE28241.1 - 0.0088 16.3 0.0 4.8 7.5 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit CLP1_P PF16575.5 EPE28241.1 - 0.012 15.5 0.5 0.89 9.3 0.0 3.1 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop IstB_IS21 PF01695.17 EPE28241.1 - 0.015 15.0 0.0 5 6.8 0.0 2.9 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 EPE28241.1 - 0.016 15.0 0.2 7.8 6.2 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EPE28241.1 - 0.017 14.7 0.1 3.2 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DRIM PF07539.12 EPE28241.1 - 0.022 13.1 0.7 1.6 7.0 0.2 2.2 1 1 1 2 2 2 0 Down-regulated in metastasis Septin PF00735.18 EPE28241.1 - 0.025 13.9 0.0 3.9 6.7 0.0 2.8 2 0 0 2 2 2 0 Septin ATP-synt_ab PF00006.25 EPE28241.1 - 0.026 14.2 0.0 9.4 5.8 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.18 EPE28241.1 - 0.036 13.8 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 EPE28241.1 - 0.041 13.6 0.0 10 5.8 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase T2SSE PF00437.20 EPE28241.1 - 0.048 12.7 1.3 3.1 6.8 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_25 PF13481.6 EPE28241.1 - 0.05 13.2 0.0 8.8 5.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EPE28241.1 - 0.062 12.7 0.0 4.9 6.5 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 EPE28241.1 - 0.062 13.2 0.1 15 5.5 0.0 2.8 2 0 0 2 2 2 0 NTPase MukB PF04310.12 EPE28241.1 - 0.076 12.8 0.1 14 5.4 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal TsaE PF02367.17 EPE28241.1 - 0.13 12.3 0.3 20 5.2 0.0 2.8 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PAS_11 PF14598.6 EPE28241.1 - 0.17 12.0 0.4 2.7 8.1 0.1 2.7 3 0 0 3 3 2 0 PAS domain V-ATPase_H_C PF11698.8 EPE28241.1 - 3 8.0 4.9 2.3 8.4 2.2 2.2 2 0 0 2 2 1 0 V-ATPase subunit H AAA_13 PF13166.6 EPE28241.1 - 5.4 5.5 12.1 2 7.0 0.0 4.1 5 0 0 5 5 4 0 AAA domain Pyr_redox_2 PF07992.14 EPE28242.1 - 5.8e-13 48.7 0.0 2e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE28242.1 - 2e-12 47.0 0.0 7.3e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EPE28242.1 - 1.4e-11 43.5 0.0 4.9e-10 38.4 0.0 2.7 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EPE28242.1 - 5.9e-09 35.5 0.0 5.1e-08 32.4 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EPE28242.1 - 2.9e-05 24.2 0.1 8.1e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EPE28242.1 - 0.0005 20.1 0.1 0.43 10.5 0.1 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 EPE28242.1 - 0.00057 19.6 0.1 0.16 11.5 0.0 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 EPE28242.1 - 0.0011 18.3 0.1 0.0021 17.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EPE28242.1 - 0.063 12.0 0.3 3.8 6.1 0.0 2.5 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.12 EPE28242.1 - 0.15 11.1 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EPE28242.1 - 6.1 7.5 5.4 8.2 7.1 0.7 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AFG1_ATPase PF03969.16 EPE28245.1 - 1.3e-97 327.0 0.0 5.6e-93 311.7 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EPE28245.1 - 0.00012 22.6 0.1 0.22 11.9 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.6 EPE28245.1 - 0.00078 19.5 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EPE28245.1 - 0.0026 18.0 0.0 0.012 15.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 EPE28245.1 - 0.0039 17.1 0.2 1.4 8.7 0.1 2.5 2 1 0 2 2 2 2 Bacterial dnaA protein TsaE PF02367.17 EPE28245.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EPE28245.1 - 0.051 14.0 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EPE28245.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EPE28245.1 - 0.11 12.4 0.0 0.37 10.7 0.0 2.0 1 1 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 EPE28245.1 - 0.15 11.6 0.5 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region R3H-assoc PF13902.6 EPE28249.1 - 2e-23 83.2 7.4 3.9e-23 82.3 6.6 1.9 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 EPE28249.1 - 8.1e-06 25.7 0.5 0.013 15.5 0.0 2.6 2 0 0 2 2 2 2 R3H domain Peptidase_M28 PF04389.17 EPE28250.1 - 4.2e-29 101.7 0.0 8.5e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EPE28250.1 - 1e-05 25.4 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 YozE_SAM_like PF06855.12 EPE28250.1 - 0.064 13.4 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 YozE SAM-like fold zf-MYND PF01753.18 EPE28252.1 - 9.2e-06 25.7 13.2 2e-05 24.6 13.2 1.6 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.13 EPE28252.1 - 0.064 11.1 1.9 0.093 10.6 1.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 GAS PF13851.6 EPE28252.1 - 0.11 11.8 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding zf-Mss51 PF13824.6 EPE28252.1 - 0.13 12.3 5.4 0.3 11.2 5.4 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Melibiase_2 PF16499.5 EPE28253.1 - 2.9e-62 210.4 4.3 6.6e-62 209.3 4.3 1.6 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EPE28253.1 - 3.4e-11 43.0 1.1 3.6e-09 36.6 0.0 2.6 3 0 0 3 3 3 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EPE28253.1 - 0.00011 21.3 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Melibiase Sugar_tr PF00083.24 EPE28255.1 - 9.5e-41 140.1 22.5 1.2e-39 136.4 22.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE28255.1 - 2.4e-36 125.4 40.0 2.1e-31 109.1 23.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_3_C PF01915.22 EPE28256.1 - 2.9e-42 144.9 0.0 4.5e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE28256.1 - 4.3e-42 144.6 0.0 7.3e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE28256.1 - 2.3e-05 24.4 0.0 6.5e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain YhfC PF10086.9 EPE28256.1 - 0.0034 16.8 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 YhfC intramembrane metalloprotease Vault_3 PF17795.1 EPE28256.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Major Vault Protein Repeat domain FlxA PF14282.6 EPE28257.1 - 0.027 14.5 3.2 0.035 14.1 3.2 1.1 1 0 0 1 1 1 0 FlxA-like protein DUF5082 PF16888.5 EPE28257.1 - 0.071 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DnaB_C PF03796.15 EPE28259.1 - 0.047 13.0 0.2 0.058 12.7 0.2 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain CAAX_1 PF15895.5 EPE28261.1 - 0.15 11.9 1.1 3.7 7.4 0.0 2.1 2 0 0 2 2 2 0 CAAX box cerebral protein 1 NACHT PF05729.12 EPE28264.1 - 0.00038 20.4 0.0 0.0018 18.2 0.0 2.2 3 0 0 3 3 2 1 NACHT domain TPR_7 PF13176.6 EPE28264.1 - 0.00085 19.2 0.5 0.0047 16.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.9 EPE28264.1 - 0.0013 18.5 0.0 0.0039 16.9 0.0 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN7 AAA_16 PF13191.6 EPE28264.1 - 0.0015 18.9 0.8 0.007 16.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain TPR_21 PF09976.9 EPE28264.1 - 0.0041 16.8 2.2 0.0079 15.9 2.2 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_2 PF07719.17 EPE28264.1 - 0.0052 16.8 2.8 0.027 14.6 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPE28264.1 - 0.0077 17.0 2.3 2.9 9.0 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat RNA_helicase PF00910.22 EPE28264.1 - 0.01 16.2 0.0 0.04 14.3 0.0 2.1 1 0 0 1 1 1 0 RNA helicase TPR_8 PF13181.6 EPE28264.1 - 0.033 14.4 0.0 0.14 12.4 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2075 PF09848.9 EPE28264.1 - 0.034 13.4 0.0 0.079 12.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TPR_1 PF00515.28 EPE28264.1 - 0.039 13.8 0.1 0.16 11.9 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Torsin PF06309.11 EPE28264.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Torsin ABC_tran PF00005.27 EPE28264.1 - 0.093 13.2 0.0 0.37 11.3 0.0 2.1 2 0 0 2 2 1 0 ABC transporter IstB_IS21 PF01695.17 EPE28264.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein CEP44 PF15007.6 EPE28264.1 - 0.12 12.5 0.1 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 Centrosomal spindle body, CEP44 NB-ARC PF00931.22 EPE28264.1 - 0.12 11.5 0.0 1 8.5 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain TPR_6 PF13174.6 EPE28264.1 - 0.13 13.0 2.0 0.46 11.2 1.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPE28264.1 - 0.48 10.8 5.1 0.12 12.7 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PGAP1 PF07819.13 EPE28265.1 - 0.0078 16.0 0.1 0.05 13.3 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein Lactonase PF10282.9 EPE28267.1 - 1.6e-20 73.7 0.0 2.7e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Zn_clus PF00172.18 EPE28268.1 - 5.7e-08 32.8 11.8 1.2e-07 31.7 11.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MARVEL PF01284.23 EPE28269.1 - 0.021 14.8 6.4 0.54 10.3 6.4 2.3 1 1 0 1 1 1 0 Membrane-associating domain Cyd_oper_YbgE PF09600.10 EPE28269.1 - 0.58 10.6 0.1 0.58 10.6 0.1 2.8 1 1 1 3 3 3 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Glyco_hydro_3_C PF01915.22 EPE28270.1 - 6.7e-44 150.3 0.0 1.1e-43 149.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE28270.1 - 1.4e-18 67.3 0.0 2.9e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE28270.1 - 6.8e-18 64.5 0.0 1.3e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.21 EPE28271.1 - 3.1e-08 33.4 0.0 3.3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Ank_2 PF12796.7 EPE28272.1 - 1.2e-73 243.7 18.0 5.3e-13 49.4 0.1 8.3 2 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE28272.1 - 2.8e-62 206.3 13.3 8.6e-09 35.8 0.1 11.1 7 3 4 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE28272.1 - 2.6e-47 153.3 14.3 0.00088 19.5 0.0 16.4 17 0 0 17 17 17 10 Ankyrin repeat Ank_5 PF13857.6 EPE28272.1 - 1.2e-43 146.6 21.0 3.5e-08 33.6 0.1 13.1 3 3 10 13 13 13 11 Ankyrin repeats (many copies) Ank PF00023.30 EPE28272.1 - 8.7e-39 130.3 25.3 0.00012 22.3 0.1 14.2 13 1 0 13 13 13 8 Ankyrin repeat NACHT PF05729.12 EPE28272.1 - 1.8e-08 34.5 0.1 5e-08 33.0 0.0 1.8 2 0 0 2 2 1 1 NACHT domain Helo_like_N PF17111.5 EPE28272.1 - 1.1e-07 31.4 0.5 2.9e-07 30.1 0.5 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 EPE28272.1 - 7.7e-05 23.0 0.0 0.00054 20.3 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 EPE28272.1 - 0.0004 20.8 0.4 0.0033 17.8 0.0 2.8 3 1 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE28272.1 - 0.0021 18.5 0.0 0.0095 16.3 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EPE28272.1 - 0.0079 15.4 0.0 0.02 14.1 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain Viral_helicase1 PF01443.18 EPE28272.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 EPE28272.1 - 0.015 15.3 0.1 0.53 10.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EPE28272.1 - 0.017 15.5 0.0 0.043 14.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Torsin PF06309.11 EPE28272.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_33 PF13671.6 EPE28272.1 - 0.097 12.8 0.0 0.36 11.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 EPE28272.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea EccE PF11203.8 EPE28272.1 - 0.73 10.2 7.4 9.1 6.7 0.8 4.6 4 1 0 4 4 4 0 Putative type VII ESX secretion system translocon, EccE ATP19 PF11022.8 EPE28273.1 - 2.8e-21 75.6 4.5 3.5e-15 56.1 0.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit K Phage_holin_3_6 PF07332.11 EPE28273.1 - 0.12 12.5 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MTP18 PF10558.9 EPE28274.1 - 3.4e-78 261.5 0.1 4.2e-78 261.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) zf-AN1 PF01428.16 EPE28275.1 - 1.8e-24 85.6 24.1 2.8e-12 46.6 8.5 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EPE28275.1 - 0.0015 18.8 9.6 0.24 11.8 1.0 2.3 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain IBR PF01485.21 EPE28275.1 - 0.0021 18.3 17.0 0.036 14.3 5.3 2.4 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain C1_4 PF07975.12 EPE28275.1 - 1.4 9.2 16.2 4.6 7.5 5.6 2.7 2 1 0 2 2 2 0 TFIIH C1-like domain Acetyltransf_7 PF13508.7 EPE28276.1 - 0.0024 18.3 0.0 0.0071 16.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 EPE28276.1 - 0.099 13.4 0.0 0.28 11.9 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PHP PF02811.19 EPE28277.1 - 0.0061 16.9 0.0 0.027 14.8 0.0 1.9 1 1 0 1 1 1 1 PHP domain MARVEL PF01284.23 EPE28278.1 - 2e-05 24.6 22.9 0.034 14.2 1.4 3.2 2 1 0 2 2 2 2 Membrane-associating domain DUF4070 PF13282.6 EPE28278.1 - 0.21 11.7 0.1 6.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) NACHT PF05729.12 EPE28279.1 - 1.1e-09 38.5 0.2 3e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.7 EPE28279.1 - 3.6e-07 30.7 0.0 1.7e-06 28.5 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE28279.1 - 1.3e-05 25.3 0.0 0.0014 18.9 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Helo_like_N PF17111.5 EPE28279.1 - 1.5e-05 24.5 1.8 3.6e-05 23.2 1.8 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 EPE28279.1 - 4e-05 23.9 0.1 0.00025 21.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Ank_4 PF13637.6 EPE28279.1 - 0.00027 21.4 0.0 0.0011 19.5 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA_16 PF13191.6 EPE28279.1 - 0.0006 20.2 0.4 0.0026 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.6 EPE28279.1 - 0.001 19.4 0.1 1.2 9.9 0.0 3.5 3 0 0 3 3 2 1 Ankyrin repeat AAA_14 PF13173.6 EPE28279.1 - 0.0096 16.0 0.9 0.32 11.0 0.9 2.6 1 1 0 1 1 1 1 AAA domain Nbl1_Borealin_N PF10444.9 EPE28279.1 - 0.011 15.3 0.0 0.085 12.5 0.0 2.5 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal FtsK_SpoIIIE PF01580.18 EPE28279.1 - 0.012 15.0 0.2 4.3 6.6 0.1 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family NB-ARC PF00931.22 EPE28279.1 - 0.024 13.9 0.0 0.062 12.5 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain Ank PF00023.30 EPE28279.1 - 0.028 14.9 0.0 0.31 11.5 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat RNA_helicase PF00910.22 EPE28279.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF1780 PF08682.10 EPE28279.1 - 0.059 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) ATPase_2 PF01637.18 EPE28279.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 EPE28279.1 - 0.092 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Peptidase_M75 PF09375.10 EPE28279.1 - 0.14 11.6 1.1 5.9 6.3 0.1 2.5 1 1 1 2 2 2 0 Imelysin YWFCY PF14293.6 EPE28279.1 - 0.14 12.5 0.1 17 5.8 0.0 2.9 2 0 0 2 2 2 0 YWFCY protein LEM PF03020.15 EPE28279.1 - 0.16 11.6 0.0 0.47 10.1 0.0 1.8 1 0 0 1 1 1 0 LEM domain Utp13 PF08625.11 EPE28279.1 - 0.25 11.2 2.5 0.73 9.7 0.4 2.7 1 1 1 2 2 2 0 Utp13 specific WD40 associated domain DHquinase_I PF01487.15 EPE28279.1 - 0.95 9.7 2.8 1.3 9.3 0.2 2.2 2 0 0 2 2 2 0 Type I 3-dehydroquinase DUF87 PF01935.17 EPE28279.1 - 1 9.4 6.0 11 6.1 0.0 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain AAL_decarboxy PF03306.13 EPE28280.1 - 9e-76 254.0 0.1 1e-75 253.9 0.1 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase TPP_enzyme_N PF02776.18 EPE28281.1 - 3.4e-45 153.7 1.3 1.4e-44 151.8 1.6 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EPE28281.1 - 1.1e-39 135.7 0.5 2.2e-39 134.7 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EPE28281.1 - 2.6e-23 82.3 0.0 5.5e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain UDPG_MGDP_dh_N PF03721.14 EPE28282.1 - 3.5e-48 163.7 0.3 1.1e-31 109.8 0.1 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EPE28282.1 - 5.8e-32 109.8 0.0 1.1e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EPE28282.1 - 1e-21 77.3 0.0 3.6e-17 62.7 0.0 3.1 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Sacchrp_dh_NADP PF03435.18 EPE28282.1 - 0.029 14.6 0.1 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 EPE28282.1 - 0.13 12.5 0.1 1.6 8.9 0.1 2.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AIP3 PF03915.13 EPE28283.1 - 0.0028 16.8 17.8 0.0028 16.8 17.8 2.1 2 0 0 2 2 2 1 Actin interacting protein 3 DUF1640 PF07798.11 EPE28283.1 - 0.0053 16.8 34.5 0.14 12.2 14.6 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF1640) DUF1016_N PF17761.1 EPE28283.1 - 0.027 14.6 0.5 0.027 14.6 0.5 2.8 4 0 0 4 4 3 0 DUF1016 N-terminal domain COMP PF11598.8 EPE28283.1 - 0.032 14.7 2.0 0.032 14.7 2.0 5.1 3 2 3 6 6 6 0 Cartilage oligomeric matrix protein Prominin PF05478.11 EPE28283.1 - 0.13 10.2 23.0 0.01 13.8 15.5 2.0 2 0 0 2 2 2 0 Prominin DUF1664 PF07889.12 EPE28283.1 - 0.19 11.8 30.0 0.094 12.8 7.2 4.5 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) Mer2 PF09074.10 EPE28283.1 - 0.24 11.2 25.8 0.14 11.9 17.7 2.4 2 0 0 2 2 2 0 Mer2 GldM_N PF12081.8 EPE28283.1 - 0.25 11.4 17.5 1.2 9.1 5.3 2.6 1 1 1 2 2 2 0 GldM N-terminal domain Baculo_PEP_C PF04513.12 EPE28283.1 - 1.1 9.3 16.6 2.3 8.3 6.0 3.8 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 EPE28283.1 - 1.4 8.9 40.9 10 6.1 13.5 3.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF883 PF05957.13 EPE28283.1 - 3.4 8.3 20.8 3.9 8.1 2.4 3.9 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF883) Mitofilin PF09731.9 EPE28283.1 - 4.9 5.9 38.8 0.019 13.8 22.2 2.8 2 1 1 3 3 3 0 Mitochondrial inner membrane protein FapA PF03961.13 EPE28283.1 - 5.3 5.5 28.1 0.88 8.1 17.6 2.8 2 1 1 3 3 3 0 Flagellar Assembly Protein A Borrelia_P83 PF05262.11 EPE28283.1 - 9 4.7 19.8 17 3.8 19.8 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Fzo_mitofusin PF04799.13 EPE28284.1 - 0.034 13.7 34.4 0.67 9.5 4.2 3.2 1 1 2 3 3 3 0 fzo-like conserved region ApoLp-III PF07464.11 EPE28284.1 - 1.9 8.6 40.8 1.2 9.3 33.9 3.0 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF3086 PF11285.8 EPE28284.1 - 2.1 7.4 22.6 0.67 9.0 19.7 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) ApoO PF09769.9 EPE28284.1 - 2.6 8.0 15.9 4.8 7.2 1.3 3.4 1 1 2 3 3 3 0 Apolipoprotein O DUF3452 PF11934.8 EPE28284.1 - 2.8 7.5 14.2 7.5 6.1 12.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) Peptidase_S46 PF10459.9 EPE28284.1 - 3.5 6.2 27.2 4 6.0 27.2 1.0 1 0 0 1 1 1 0 Peptidase S46 HNH_2 PF13391.6 EPE28286.1 - 0.0012 18.9 0.0 0.0029 17.7 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease ORF6C PF10552.9 EPE28286.1 - 0.093 12.8 2.1 0.13 12.3 1.0 1.8 1 1 1 2 2 2 0 ORF6C domain YkyA PF10368.9 EPE28286.1 - 0.094 12.4 2.2 0.17 11.5 2.2 1.4 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein SNARE PF05739.19 EPE28286.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 SNARE domain AATF-Che1 PF13339.6 EPE28287.1 - 0.00089 20.0 0.1 0.001 19.7 0.1 1.1 1 0 0 1 1 1 1 Apoptosis antagonizing transcription factor COG5 PF10392.9 EPE28287.1 - 0.0022 18.2 0.2 0.003 17.7 0.2 1.1 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Spc7 PF08317.11 EPE28287.1 - 0.05 12.5 0.6 0.051 12.4 0.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein CSN5_C PF18323.1 EPE28287.1 - 0.076 13.9 4.1 2.3 9.2 4.1 2.0 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain SlyX PF04102.12 EPE28287.1 - 0.14 12.8 2.8 0.21 12.2 2.7 1.5 1 1 0 1 1 1 0 SlyX Claudin_2 PF13903.6 EPE28288.1 - 0.041 13.6 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4407 PF14362.6 EPE28288.1 - 0.17 11.2 0.4 0.25 10.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LppA PF16708.5 EPE28289.1 - 0.011 15.7 2.0 0.4 10.6 0.1 2.3 1 1 1 2 2 2 0 Lipoprotein confined to pathogenic Mycobacterium Phage_GP20 PF06810.11 EPE28289.1 - 0.024 14.4 0.8 0.049 13.4 0.3 1.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 LemA PF04011.12 EPE28289.1 - 0.12 12.2 6.5 1.1 9.1 0.4 2.9 1 1 2 3 3 3 0 LemA family DUF3138 PF11336.8 EPE28289.1 - 0.13 10.8 0.1 0.17 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spc7 PF08317.11 EPE28289.1 - 0.14 11.1 7.5 0.19 10.5 7.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CCDC53 PF10152.9 EPE28289.1 - 0.2 12.1 12.4 0.29 11.5 3.6 2.4 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex DUF908 PF06012.12 EPE28289.1 - 0.21 11.0 12.3 0.09 12.2 10.3 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) zf-RING_9 PF13901.6 EPE28289.1 - 0.29 11.1 6.0 0.42 10.6 6.0 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Cluap1 PF10234.9 EPE28289.1 - 0.43 9.9 6.3 0.71 9.2 0.0 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 Filament PF00038.21 EPE28289.1 - 0.46 10.0 10.3 1 8.8 10.4 1.5 1 1 0 1 1 1 0 Intermediate filament protein YlbD_coat PF14071.6 EPE28289.1 - 0.89 9.8 8.1 5.9 7.2 6.1 2.2 1 1 1 2 2 2 0 Putative coat protein Baculo_p24 PF05073.12 EPE28289.1 - 4 7.2 8.4 3.3 7.5 2.2 2.2 1 1 1 2 2 2 0 Baculovirus P24 capsid protein CorA PF01544.18 EPE28289.1 - 7.2 5.8 8.6 3 7.1 5.3 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein RIFIN PF02009.16 EPE28290.1 - 2.2 8.1 7.5 4.4 7.1 7.5 1.4 1 0 0 1 1 1 0 Rifin zf-C2H2_4 PF13894.6 EPE28292.1 - 6.6e-15 54.5 93.3 0.0028 18.3 0.0 16.4 17 0 0 17 17 17 7 C2H2-type zinc finger zf-C2H2 PF00096.26 EPE28292.1 - 3e-13 49.4 91.1 0.0024 18.2 0.1 15.7 16 0 0 16 16 15 6 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EPE28292.1 - 1.3e-07 31.4 0.9 0.00061 19.7 0.1 12.3 12 1 1 13 13 13 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPE28292.1 - 0.00034 20.9 81.7 0.21 12.1 0.4 13.6 13 1 0 13 13 13 4 Zinc-finger double domain zf-C2HC_2 PF13913.6 EPE28292.1 - 0.0035 17.2 0.0 0.0035 17.2 0.0 8.2 8 0 0 8 8 7 1 zinc-finger of a C2HC-type zinc_ribbon_15 PF17032.5 EPE28292.1 - 0.0093 16.7 44.7 0.89 10.3 0.4 7.3 6 2 1 7 7 7 5 zinc-ribbon family Zn-C2H2_12 PF18112.1 EPE28292.1 - 0.03 14.8 0.2 0.03 14.8 0.2 5.5 6 0 0 6 6 6 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_jaz PF12171.8 EPE28292.1 - 0.11 12.8 0.1 0.11 12.8 0.1 13.8 16 0 0 16 16 16 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 EPE28292.1 - 0.24 11.0 37.2 4.7 6.9 0.1 10.0 9 0 0 9 9 9 0 Ubiquitin-Binding Zinc Finger C1_1 PF00130.22 EPE28292.1 - 1.6 8.7 45.8 0.17 11.8 0.3 8.8 6 3 2 9 9 9 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_11 PF16622.5 EPE28292.1 - 2.3 8.1 16.7 42 4.0 0.0 7.9 9 0 0 9 9 9 0 zinc-finger C2H2-type zf-met PF12874.7 EPE28292.1 - 2.3 8.7 51.9 0.22 12.0 0.7 11.5 13 0 0 13 13 13 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 EPE28292.1 - 3.2 7.7 14.3 35 4.4 0.1 5.7 5 1 0 5 5 5 0 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 EPE28292.1 - 8.7 6.3 10.2 15 5.5 0.1 4.7 4 0 0 4 4 4 0 Rad50 zinc hook motif Methyltransf_2 PF00891.18 EPE28293.1 - 2.7e-25 88.9 0.0 4.2e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Sigma70_r4 PF04545.16 EPE28293.1 - 0.017 14.7 0.0 0.041 13.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 BCDHK_Adom3 PF10436.9 EPE28294.1 - 1.1e-49 168.3 0.0 1.6e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EPE28294.1 - 2.2e-09 37.8 0.0 7e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.16 EPE28295.1 - 0.075 13.7 0.0 0.075 13.7 0.0 1.3 1 1 0 1 1 1 0 Peptidase inhibitor I9 RIBIOP_C PF04950.12 EPE28296.1 - 6.2e-94 314.7 0.2 1.3e-93 313.6 0.2 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EPE28296.1 - 7.8e-30 102.8 0.0 4e-29 100.5 0.0 2.4 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 EPE28296.1 - 1e-05 25.8 0.0 3.5e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EPE28296.1 - 0.00013 22.2 0.0 0.00037 20.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPE28296.1 - 0.00019 21.8 0.0 0.00055 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EPE28296.1 - 0.00047 20.1 0.0 0.00097 19.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain GTP_EFTU PF00009.27 EPE28296.1 - 0.00056 19.5 0.0 0.22 11.1 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 EPE28296.1 - 0.00081 19.8 0.0 0.002 18.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EPE28296.1 - 0.0011 19.1 0.0 0.0037 17.3 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EPE28296.1 - 0.002 17.9 0.0 0.0065 16.2 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EPE28296.1 - 0.0037 17.8 2.2 0.007 16.9 0.0 2.6 3 0 0 3 3 2 1 ABC transporter AAA_19 PF13245.6 EPE28296.1 - 0.0041 17.5 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPE28296.1 - 0.0051 16.5 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EPE28296.1 - 0.0054 16.0 0.0 0.022 14.0 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.15 EPE28296.1 - 0.0061 16.5 0.2 0.059 13.3 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 EPE28296.1 - 0.0077 16.6 0.1 0.029 14.8 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 EPE28296.1 - 0.0094 16.5 0.0 0.0094 16.5 0.0 3.5 4 0 0 4 4 2 1 AAA domain MobB PF03205.14 EPE28296.1 - 0.017 15.0 1.1 0.69 9.8 0.1 2.9 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ploopntkinase3 PF18751.1 EPE28296.1 - 0.017 15.0 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Roc PF08477.13 EPE28296.1 - 0.019 15.2 0.1 0.076 13.2 0.0 2.0 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EPE28296.1 - 0.02 14.9 0.0 0.072 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EPE28296.1 - 0.025 14.5 1.1 0.046 13.6 0.0 2.0 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 EPE28296.1 - 0.025 14.2 0.1 0.056 13.0 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EPE28296.1 - 0.026 14.4 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 EPE28296.1 - 0.031 14.5 1.3 0.061 13.6 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 EPE28296.1 - 0.043 13.8 0.5 0.18 11.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EPE28296.1 - 0.054 13.4 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 NTPase AAA_17 PF13207.6 EPE28296.1 - 0.069 13.6 0.1 0.069 13.6 0.1 3.1 3 1 0 3 3 2 0 AAA domain AAA_7 PF12775.7 EPE28296.1 - 0.085 12.4 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 EPE28296.1 - 0.33 10.4 0.0 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ADH_zinc_N PF00107.26 EPE28297.1 - 2e-20 73.1 0.4 3.2e-20 72.4 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE28297.1 - 4.7e-09 37.4 0.0 8.8e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE28297.1 - 0.008 16.1 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EPE28297.1 - 0.025 14.1 0.1 0.035 13.6 0.1 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Rotamase_3 PF13616.6 EPE28297.1 - 0.083 13.4 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain NACHT PF05729.12 EPE28299.1 - 1.3e-07 31.7 0.0 3e-07 30.5 0.0 1.7 2 0 0 2 2 1 1 NACHT domain AAA_16 PF13191.6 EPE28299.1 - 1.2e-06 29.0 0.0 2.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPE28299.1 - 0.0002 21.7 0.0 0.00068 19.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EPE28299.1 - 0.00021 20.6 0.0 0.0004 19.7 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain ATPase PF06745.13 EPE28299.1 - 0.00036 20.0 0.4 0.0012 18.2 0.0 2.0 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 EPE28299.1 - 0.00042 20.0 0.0 0.00074 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EPE28299.1 - 0.00066 20.1 2.6 0.014 15.8 0.0 3.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EPE28299.1 - 0.0007 18.9 0.0 0.0051 16.1 0.0 2.4 2 1 0 2 2 2 1 Zeta toxin KAP_NTPase PF07693.14 EPE28299.1 - 0.0013 18.1 4.0 0.0068 15.7 0.0 2.6 2 1 1 3 3 3 1 KAP family P-loop domain AAA_19 PF13245.6 EPE28299.1 - 0.011 16.1 0.4 0.04 14.2 0.1 2.1 2 1 0 2 2 2 0 AAA domain CCDC92 PF14916.6 EPE28299.1 - 0.012 15.4 0.4 0.029 14.1 0.4 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function AAA_33 PF13671.6 EPE28299.1 - 0.035 14.3 0.0 0.13 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EPE28299.1 - 0.038 14.0 0.1 0.23 11.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain Torsin PF06309.11 EPE28299.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA_30 PF13604.6 EPE28299.1 - 0.051 13.3 0.2 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain SAP30_Sin3_bdg PF13867.6 EPE28299.1 - 0.07 13.5 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF3053 PF11254.8 EPE28299.1 - 0.071 12.7 0.3 0.54 9.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) FlaC_arch PF05377.11 EPE28299.1 - 0.092 13.2 0.5 0.5 10.8 0.5 2.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Methyltransf_32 PF13679.6 EPE28299.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain ImcF-related_N PF14331.6 EPE28299.1 - 0.22 10.9 2.8 0.097 12.0 0.3 1.6 2 0 0 2 2 2 0 ImcF-related N-terminal domain DUF5494 PF17598.2 EPE28301.1 - 0.042 14.0 0.1 0.085 13.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5494) MRP PF09387.10 EPE28301.1 - 0.043 13.8 0.1 8.7 6.3 0.0 2.3 1 1 1 2 2 2 0 Mitochondrial RNA binding protein MRP KELK PF15796.5 EPE28301.1 - 0.69 10.4 5.5 2.8 8.5 0.2 2.8 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SKA2 PF16740.5 EPE28301.1 - 1.3 8.8 7.0 8.6 6.2 0.3 2.6 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Cyclase PF04199.13 EPE28302.1 - 2.2e-17 63.6 0.0 2.9e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.24 EPE28303.1 - 8.6e-118 394.0 23.5 9.8e-118 393.9 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE28303.1 - 1.2e-23 83.7 46.3 2.5e-17 62.9 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Proton_antipo_N PF00662.20 EPE28303.1 - 0.11 12.5 0.3 0.11 12.5 0.3 2.1 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus RBDV_coat PF06593.11 EPE28304.1 - 0.044 13.3 1.6 0.087 12.3 1.2 1.6 1 1 1 2 2 2 0 Raspberry bushy dwarf virus coat protein DUF241 PF03087.14 EPE28304.1 - 0.066 13.0 2.2 0.23 11.3 0.7 2.0 2 0 0 2 2 2 0 Arabidopsis protein of unknown function SOG2 PF10428.9 EPE28304.1 - 0.076 12.2 13.7 0.09 12.0 13.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_L28e PF01778.17 EPE28304.1 - 1.4 9.7 7.1 0.37 11.5 2.2 1.9 1 1 1 2 2 2 0 Ribosomal L28e protein family MFS_1 PF07690.16 EPE28305.1 - 1.5e-29 103.0 28.5 2.3e-29 102.4 28.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1772 PF08592.11 EPE28305.1 - 0.0081 16.5 1.6 0.0081 16.5 1.6 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF1772) Ank_2 PF12796.7 EPE28306.1 - 9e-49 164.0 4.2 9.8e-19 67.7 0.1 5.0 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE28306.1 - 1.9e-34 117.6 1.6 1.3e-15 57.5 0.0 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EPE28306.1 - 2e-34 116.5 11.0 1.1e-05 25.7 0.0 7.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 EPE28306.1 - 2.2e-34 113.6 1.8 4e-05 23.7 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 EPE28306.1 - 1.3e-24 85.9 4.1 8.8e-06 25.9 0.0 6.6 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE28307.1 - 1.3e-22 80.2 1.3 3e-11 43.8 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EPE28307.1 - 5.6e-17 61.3 0.6 0.00019 21.7 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EPE28307.1 - 3e-15 56.4 0.0 3.9e-05 24.1 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE28307.1 - 9.6e-14 50.2 0.3 0.0036 17.7 0.0 5.1 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EPE28307.1 - 1.4e-12 47.5 0.4 4.5e-05 23.7 0.0 4.1 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Mur_ligase PF01225.25 EPE28307.1 - 0.1 13.0 0.0 0.3 11.5 0.0 1.8 2 0 0 2 2 2 0 Mur ligase family, catalytic domain UreE_N PF02814.15 EPE28310.1 - 0.093 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Pyr_redox_2 PF07992.14 EPE28310.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE28311.1 - 3.6e-06 27.1 0.0 7.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EPE28311.1 - 0.00011 21.6 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EPE28311.1 - 0.00015 21.2 0.0 0.00024 20.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EPE28311.1 - 0.0014 18.0 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE28311.1 - 0.004 17.7 0.1 0.044 14.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE28311.1 - 0.0056 15.8 0.0 0.0077 15.3 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EPE28311.1 - 0.0094 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE28311.1 - 0.0096 15.0 0.3 0.016 14.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 EPE28311.1 - 0.02 15.1 0.0 0.033 14.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 EPE28311.1 - 0.026 13.2 0.0 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 EPE28311.1 - 0.038 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase SnoaL_2 PF12680.7 EPE28311.1 - 0.097 13.3 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain AlaDh_PNT_C PF01262.21 EPE28311.1 - 0.23 10.8 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4585 PF15232.6 EPE28312.1 - 0.034 14.2 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4585) SIR2 PF02146.17 EPE28313.1 - 4.1e-29 101.8 0.0 3.3e-10 40.2 0.0 3.3 2 1 1 3 3 3 3 Sir2 family zf-CHY PF05495.12 EPE28314.1 - 1.2e-11 45.0 7.3 1.7e-11 44.4 7.3 1.3 1 0 0 1 1 1 1 CHY zinc finger zinc_ribbon_12 PF11331.8 EPE28314.1 - 0.008 16.0 4.0 0.021 14.6 0.1 2.4 2 0 0 2 2 2 1 Probable zinc-ribbon domain RDD PF06271.12 EPE28315.1 - 0.11 12.7 0.1 0.33 11.2 0.1 1.8 1 0 0 1 1 1 0 RDD family CENP-L PF13092.6 EPE28316.1 - 8.7e-44 149.6 0.0 1.2e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 peroxidase PF00141.23 EPE28317.1 - 7.1e-28 97.9 0.2 1.1e-27 97.2 0.2 1.3 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 EPE28317.1 - 0.0068 16.3 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 Fungal peroxidase extension region DUF1774 PF08611.10 EPE28318.1 - 2.6e-36 123.8 3.4 2.6e-36 123.8 3.4 2.6 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Zn_clus PF00172.18 EPE28319.1 - 8.5e-08 32.2 8.8 1.5e-07 31.5 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE28319.1 - 0.0076 15.3 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tho1_MOS11_C PF18592.1 EPE28319.1 - 0.1 12.4 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain MAGP PF05507.11 EPE28319.1 - 0.18 12.2 0.6 0.32 11.4 0.6 1.3 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) SGL PF08450.12 EPE28320.1 - 7.3e-24 84.7 0.1 1.9e-23 83.3 0.1 1.7 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region DUF5074 PF16819.5 EPE28320.1 - 0.17 12.0 0.0 0.75 9.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) DUF4972 PF16342.5 EPE28322.1 - 0.0031 17.2 1.5 0.0073 16.0 0.9 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4972) Occludin_ELL PF07303.13 EPE28322.1 - 0.15 12.8 5.9 0.32 11.8 3.9 2.4 1 1 1 2 2 2 0 Occludin homology domain YgaB PF14182.6 EPE28322.1 - 0.22 11.9 3.4 0.24 11.8 0.9 2.1 2 0 0 2 2 2 0 YgaB-like protein CorA PF01544.18 EPE28322.1 - 3.3 6.9 6.3 2.8 7.2 0.8 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Acylphosphatase PF00708.18 EPE28330.1 - 4.6e-25 87.8 0.2 5.1e-25 87.7 0.2 1.0 1 0 0 1 1 1 1 Acylphosphatase F-box-like PF12937.7 EPE28331.1 - 3.3e-05 23.7 0.2 0.00012 21.9 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE28331.1 - 8.4e-05 22.3 0.2 0.00034 20.4 0.2 2.2 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EPE28331.1 - 0.0037 17.1 0.3 0.019 14.8 0.1 2.3 3 0 0 3 3 3 1 F-box F-box-like PF12937.7 EPE28332.1 - 0.016 15.1 0.1 0.056 13.4 0.1 1.9 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 EPE28332.1 - 0.029 14.3 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 F-box Glyco_hydro_cc PF11790.8 EPE28333.1 - 2.6e-75 253.1 0.4 3e-75 252.9 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Thiolase_N PF00108.23 EPE28334.1 - 1.5e-71 240.8 0.0 2.1e-71 240.4 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EPE28334.1 - 4.7e-40 136.1 0.7 8e-40 135.3 0.2 1.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EPE28334.1 - 0.014 15.0 3.1 0.081 12.5 2.4 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EPE28334.1 - 0.063 13.1 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SepQ PF06622.11 EPE28335.1 - 0.18 10.9 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 SepQ protein Lactamase_B_2 PF12706.7 EPE28336.1 - 1.7e-08 34.2 0.1 4.1e-08 33.0 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EPE28336.1 - 3.8e-06 26.9 0.1 6.8e-06 26.1 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain MASE4 PF17158.4 EPE28337.1 - 0.0051 16.1 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Membrane-associated sensor, integral membrane domain Isochorismatase PF00857.20 EPE28339.1 - 2.9e-40 138.3 0.0 3.3e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family OTU PF02338.19 EPE28340.1 - 5.8e-09 36.5 0.2 2e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease CUE PF02845.16 EPE28340.1 - 0.0088 15.7 0.1 0.018 14.8 0.1 1.5 1 0 0 1 1 1 1 CUE domain COG4 PF08318.12 EPE28340.1 - 0.041 12.9 2.1 0.07 12.2 2.1 1.3 1 0 0 1 1 1 0 COG4 transport protein DUF4666 PF15697.5 EPE28340.1 - 3.1 8.5 7.3 0.47 11.2 0.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4666) SLAC1 PF03595.17 EPE28341.1 - 3.4e-69 233.6 48.2 3.9e-69 233.4 48.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Senescence PF06911.12 EPE28342.1 - 2e-56 191.2 10.6 3.1e-56 190.6 10.6 1.3 1 0 0 1 1 1 1 Senescence-associated protein Fungal_trans PF04082.18 EPE28343.1 - 2.8e-25 88.9 0.2 8.8e-25 87.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE28343.1 - 4.5e-05 23.5 8.9 8.8e-05 22.6 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GCP_N_terminal PF17681.1 EPE28344.1 - 3e-25 89.5 0.0 4.6e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EPE28344.1 - 5.2e-18 65.6 0.0 1.4e-17 64.2 0.0 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal Mating_N PF12731.7 EPE28344.1 - 0.34 11.0 1.0 4.1 7.5 0.1 2.6 2 0 0 2 2 2 0 Mating-type protein beta 1 Thioredoxin PF00085.20 EPE28346.1 - 7.1e-29 99.8 0.1 8e-29 99.7 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 EPE28346.1 - 4.9e-08 32.8 0.0 5.5e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EPE28346.1 - 1.7e-06 28.5 0.5 6.8e-06 26.5 0.5 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EPE28346.1 - 3.3e-06 27.3 0.0 1.2e-05 25.6 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.16 EPE28346.1 - 4.2e-05 22.6 0.0 4.7e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Phosducin Redoxin PF08534.10 EPE28346.1 - 0.00011 22.0 0.6 0.0085 15.8 0.3 2.0 1 1 1 2 2 2 2 Redoxin OST3_OST6 PF04756.13 EPE28346.1 - 0.00025 20.5 0.0 0.00028 20.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EPE28346.1 - 0.0027 17.6 0.2 0.0055 16.6 0.2 1.5 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 EPE28346.1 - 0.0034 17.2 0.1 0.0038 17.1 0.1 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredox_DsbH PF03190.15 EPE28346.1 - 0.0041 17.1 0.4 0.0076 16.2 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 EPE28346.1 - 0.014 15.6 0.2 0.033 14.4 0.2 1.7 1 1 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 EPE28346.1 - 0.075 13.3 0.5 0.13 12.5 0.5 1.5 1 1 0 1 1 1 0 Glutaredoxin PCYCGC PF13798.6 EPE28346.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function with PCYCGC motif Nucleo_P87 PF07267.11 EPE28347.1 - 0.27 10.1 2.4 0.29 10.0 2.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 EPE28347.1 - 4.9 5.3 7.4 5.4 5.2 7.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_2 PF00891.18 EPE28348.1 - 1.4e-19 70.3 0.0 1.9e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 EPE28348.1 - 0.13 12.3 4.3 0.12 12.4 0.8 2.7 2 1 0 2 2 2 0 Dimerisation domain COPI_assoc PF08507.10 EPE28349.1 - 2.1e-32 111.9 4.1 2.4e-32 111.7 4.1 1.0 1 0 0 1 1 1 1 COPI associated protein UCR_Fe-S_N PF10399.9 EPE28349.1 - 0.071 12.5 0.3 0.12 11.8 0.3 1.3 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF2583 PF10762.9 EPE28349.1 - 0.084 13.3 2.7 1.4 9.4 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) Neurensin PF14927.6 EPE28349.1 - 0.19 11.4 2.6 0.24 11.1 1.5 1.8 1 1 1 2 2 2 0 Neurensin DUF2157 PF09925.9 EPE28349.1 - 1.7 8.4 6.0 4.9 6.9 6.0 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) MNHE PF01899.16 EPE28349.1 - 2.9 7.7 4.6 12 5.6 2.8 2.0 1 1 1 2 2 2 0 Na+/H+ ion antiporter subunit Acyltransferase PF01553.21 EPE28350.1 - 2e-16 59.8 0.0 1.2e-15 57.3 0.0 2.2 2 0 0 2 2 2 1 Acyltransferase UPF0086 PF01868.16 EPE28351.1 - 1.4e-25 89.0 0.4 2.1e-25 88.4 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Fungal_trans_2 PF11951.8 EPE28352.1 - 3.5e-12 45.8 3.9 2e-11 43.3 3.9 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE28352.1 - 5.7e-07 29.6 9.4 1.1e-06 28.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 EPE28353.1 - 4.9e-25 88.6 0.0 1.2e-24 87.3 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.32 EPE28353.1 - 0.00022 21.9 9.8 1.4 9.9 0.1 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE28353.1 - 0.042 14.2 0.8 0.38 11.1 0.1 3.0 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_C550 PF14495.6 EPE28354.1 - 0.07 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c-550 domain PQ-loop PF04193.14 EPE28355.1 - 1.1e-11 44.3 1.3 1.1e-11 44.3 1.3 2.1 1 1 1 2 2 2 1 PQ loop repeat Hemerythrin PF01814.23 EPE28356.1 - 1.4e-07 32.2 1.1 1.9e-07 31.8 0.6 1.6 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain Afaf PF15339.6 EPE28356.1 - 0.027 14.2 0.1 0.039 13.7 0.1 1.2 1 0 0 1 1 1 0 Acrosome formation-associated factor XAP5 PF04921.14 EPE28357.1 - 3.4e-90 302.2 0.0 5e-90 301.7 0.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator TPR_1 PF00515.28 EPE28358.1 - 5.2e-07 29.2 3.6 0.0002 21.0 0.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPE28358.1 - 6.5e-07 29.0 2.2 0.0055 16.7 0.5 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPE28358.1 - 4.6e-06 26.8 0.9 1.1e-05 25.6 0.9 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EPE28358.1 - 0.00016 21.3 1.7 0.00026 20.6 1.0 1.7 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 EPE28358.1 - 0.0002 21.2 0.9 0.15 12.2 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EPE28358.1 - 0.0063 17.2 2.9 0.025 15.4 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPE28358.1 - 0.064 13.9 1.6 1.3 9.8 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Dermcidin PF15291.6 EPE28358.1 - 0.07 13.7 1.1 0.17 12.4 0.3 2.1 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide HAD_2 PF13419.6 EPE28359.1 - 1.1e-13 51.7 0.0 2.3e-13 50.6 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPE28359.1 - 9.1e-07 29.4 0.0 2.2e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPE28359.1 - 0.00098 19.1 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like DUF1722 PF08349.11 EPE28361.1 - 0.0071 16.6 0.0 0.011 16.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1722) KinB_sensor PF16767.5 EPE28361.1 - 0.16 12.5 0.1 3.6 8.1 0.0 2.1 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB Acetyltransf_10 PF13673.7 EPE28362.1 - 1.1e-06 28.7 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE28362.1 - 5e-06 26.9 0.0 8.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE28362.1 - 0.00014 22.1 0.0 0.00026 21.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EPE28362.1 - 0.0043 17.1 0.0 0.0091 16.1 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Ribosomal_S24e PF01282.19 EPE28362.1 - 0.027 14.4 0.0 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S24e FR47 PF08445.10 EPE28362.1 - 0.029 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DUF3112 PF11309.8 EPE28363.1 - 1.7e-13 50.6 6.8 1.2e-11 44.5 0.2 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) Metallophos PF00149.28 EPE28364.1 - 5.8e-38 131.4 0.5 9.3e-38 130.8 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EPE28364.1 - 0.1 13.1 0.1 0.2 12.1 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Exo84_C PF16528.5 EPE28365.1 - 3.7e-74 249.0 0.5 3.7e-74 249.0 0.5 2.6 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EPE28365.1 - 1.6e-15 56.9 4.3 4.5e-15 55.5 4.3 1.8 1 0 0 1 1 1 1 Vps51/Vps67 Alpha-2-MRAP_C PF06401.11 EPE28365.1 - 0.014 15.4 3.4 0.054 13.5 3.4 1.9 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain SATase_N PF06426.14 EPE28365.1 - 0.053 13.9 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal TSC22 PF01166.18 EPE28365.1 - 0.11 12.8 1.2 9.1 6.7 0.1 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family COG2 PF06148.11 EPE28365.1 - 0.15 12.1 3.0 0.35 11.0 0.4 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_L PF02601.15 EPE28365.1 - 0.38 10.3 6.4 0.88 9.1 2.1 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit APG6_N PF17675.1 EPE28365.1 - 0.6 10.6 12.4 0.19 12.3 4.3 3.0 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF1640 PF07798.11 EPE28365.1 - 0.75 9.8 6.6 0.32 11.0 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) HMMR_C PF15908.5 EPE28365.1 - 1.6 9.0 6.4 0.32 11.3 2.1 2.0 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal DUF4407 PF14362.6 EPE28365.1 - 1.8 7.8 5.4 8 5.7 5.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 EPE28365.1 - 2.4 6.6 4.9 0.4 9.2 1.0 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF4618 PF15397.6 EPE28365.1 - 4.5 6.6 11.4 0.24 10.8 3.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) MAS20 PF02064.15 EPE28366.1 - 1.9e-42 144.4 3.8 4.3e-41 140.0 3.8 2.0 1 1 0 1 1 1 1 MAS20 protein import receptor PMC2NT PF08066.12 EPE28366.1 - 0.15 12.8 0.0 0.24 12.1 0.0 1.3 1 0 0 1 1 1 0 PMC2NT (NUC016) domain AAA_6 PF12774.7 EPE28367.1 - 1.7e-126 421.6 0.0 7.5e-126 419.5 0.0 2.2 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EPE28367.1 - 4.3e-126 421.8 5.6 4.3e-126 421.8 5.6 3.9 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EPE28367.1 - 1.3e-117 393.3 7.4 1.3e-117 393.3 7.4 5.0 5 1 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EPE28367.1 - 1.5e-73 246.6 1.0 1.5e-73 246.6 1.0 4.0 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 EPE28367.1 - 5.1e-68 229.2 0.0 6.4e-67 225.6 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EPE28367.1 - 4e-41 140.5 0.0 9.4e-35 119.8 0.0 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 EPE28367.1 - 1.8e-40 139.0 5.7 1.8e-40 139.0 5.7 2.5 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EPE28367.1 - 1.1e-31 109.7 2.4 2.8e-11 43.6 0.0 7.6 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 EPE28367.1 - 8.7e-31 106.5 0.0 8.6e-28 96.8 0.0 4.2 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 EPE28367.1 - 4.8e-27 94.8 0.0 1.3e-26 93.3 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EPE28367.1 - 3.8e-15 56.4 0.4 0.01 16.1 0.0 6.0 4 1 0 4 4 4 3 AAA domain AAA PF00004.29 EPE28367.1 - 3.3e-13 50.2 0.0 0.0022 18.4 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) Dynein_AAA_lid PF17852.1 EPE28367.1 - 1.2e-12 48.0 0.0 5.4e-12 45.9 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 EPE28367.1 - 6.1e-11 43.0 0.1 1.8 8.9 0.0 7.6 6 0 0 6 6 6 1 AAA ATPase domain AAA_33 PF13671.6 EPE28367.1 - 3.8e-10 40.1 0.6 0.16 12.1 0.0 5.1 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.6 EPE28367.1 - 1.3e-09 38.7 0.9 0.057 14.0 0.0 5.8 5 0 0 5 5 4 2 AAA domain T2SSE PF00437.20 EPE28367.1 - 2.9e-06 26.6 0.0 0.022 13.8 0.0 3.7 3 0 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 EPE28367.1 - 5.9e-06 25.8 0.9 0.66 9.3 0.0 4.7 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 EPE28367.1 - 2.6e-05 24.3 0.0 0.00024 21.3 0.0 2.8 1 0 0 1 1 1 1 AAA+ lid domain ABC_tran PF00005.27 EPE28367.1 - 2.7e-05 24.7 0.1 3.2 8.3 0.1 5.0 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.6 EPE28367.1 - 7.6e-05 22.4 0.1 2.3 8.0 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_19 PF13245.6 EPE28367.1 - 0.00032 21.1 0.7 0.28 11.5 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 EPE28367.1 - 0.00064 19.5 0.6 39 3.9 0.0 4.9 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 EPE28367.1 - 0.0021 17.7 0.0 0.31 10.6 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EPE28367.1 - 0.0023 17.7 0.4 9.9 5.8 0.0 4.3 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 EPE28367.1 - 0.003 17.3 0.9 0.77 9.5 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 EPE28367.1 - 0.0041 16.5 3.0 2.4 7.5 0.0 4.0 4 0 0 4 4 3 1 FtsK/SpoIIIE family RNA_helicase PF00910.22 EPE28367.1 - 0.006 17.0 0.1 23 5.4 0.0 4.7 4 0 0 4 4 4 0 RNA helicase CLZ PF16526.5 EPE28367.1 - 0.0067 16.8 1.6 0.0067 16.8 1.6 4.1 3 0 0 3 3 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Rad17 PF03215.15 EPE28367.1 - 0.032 14.2 1.3 6.8 6.6 0.0 4.3 5 0 0 5 5 5 0 Rad17 P-loop domain Vps23_core PF09454.10 EPE28367.1 - 0.085 12.8 0.5 17 5.5 0.2 3.0 2 0 0 2 2 2 0 Vps23 core domain AAA_17 PF13207.6 EPE28367.1 - 0.52 10.7 2.5 1.5e+02 2.8 0.0 4.7 4 0 0 4 4 4 0 AAA domain Phage_GP20 PF06810.11 EPE28367.1 - 1 9.2 16.5 0.62 9.9 3.5 4.0 4 0 0 4 4 3 0 Phage minor structural protein GP20 DUF4482 PF14818.6 EPE28367.1 - 1.9 9.4 9.6 43 5.0 7.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) NTPase_1 PF03266.15 EPE28367.1 - 3 7.7 5.8 47 3.9 0.0 4.3 5 0 0 5 5 5 0 NTPase NACHT PF05729.12 EPE28367.1 - 3.3 7.6 6.5 31 4.4 0.0 4.4 4 0 0 4 4 3 0 NACHT domain adh_short PF00106.25 EPE28368.1 - 0.11 11.9 0.3 0.35 10.3 0.1 1.6 1 1 1 2 2 2 0 short chain dehydrogenase CorA PF01544.18 EPE28369.1 - 1.2e-09 37.9 1.8 1.9e-09 37.3 0.0 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein AMH_N PF04709.12 EPE28369.1 - 0.08 11.8 0.5 0.14 11.1 0.5 1.3 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region Histone PF00125.24 EPE28370.1 - 1.2e-07 32.2 0.0 1.7e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EPE28370.1 - 1.7e-07 31.3 0.0 2.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EPE28370.1 - 4.4e-07 30.1 0.0 8.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 EPE28370.1 - 0.00014 22.0 0.1 0.00014 22.0 0.1 1.6 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 EPE28370.1 - 0.00033 20.7 0.0 0.00041 20.4 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.16 EPE28370.1 - 0.003 17.5 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit IF-2 PF11987.8 EPE28370.1 - 0.026 14.7 0.0 0.3 11.2 0.0 2.0 1 1 0 2 2 2 0 Translation-initiation factor 2 CENP-S PF15630.6 EPE28370.1 - 0.073 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 CENP-S protein Svf1_C PF17187.4 EPE28371.1 - 9.5e-60 201.2 0.3 5.6e-59 198.7 0.0 2.1 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EPE28371.1 - 2.5e-57 193.5 0.1 3.9e-57 192.9 0.1 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain DUF2231 PF09990.9 EPE28372.1 - 5e-08 33.3 0.2 8.7e-08 32.5 0.2 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2231) DUF4166 PF13761.6 EPE28374.1 - 0.024 14.4 0.1 0.035 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4166) HTH_23 PF13384.6 EPE28375.1 - 0.14 12.0 0.0 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Cpn10 PF00166.21 EPE28376.1 - 4.4e-27 94.0 0.0 4.9e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase PF00069.25 EPE28377.1 - 1.6e-48 165.4 0.0 2.5e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE28377.1 - 2.1e-21 76.4 0.0 2.8e-20 72.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EPE28377.1 - 0.0037 17.2 0.0 0.0084 16.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EPE28377.1 - 0.057 12.3 1.2 0.093 11.7 0.0 1.9 2 1 0 2 2 2 0 Haspin like kinase domain Ribosomal_L11_N PF03946.14 EPE28378.1 - 1.1e-25 89.3 0.2 1.6e-25 88.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EPE28378.1 - 4.6e-22 78.3 0.2 7.2e-22 77.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain CDH-cyt PF16010.5 EPE28379.1 - 1.6e-44 151.7 9.8 2e-44 151.5 9.8 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF4267 PF14087.6 EPE28380.1 - 3e-23 82.0 5.2 3.4e-23 81.8 5.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) MoCF_biosynth PF00994.24 EPE28381.1 - 5.6e-54 181.7 0.8 1.3e-27 96.2 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EPE28381.1 - 2.2e-40 138.0 2.3 4.1e-40 137.1 2.3 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EPE28381.1 - 4.2e-16 58.9 0.0 1.4e-15 57.2 0.0 2.0 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 EPE28381.1 - 0.36 10.2 10.9 0.54 9.6 10.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ATP_bind_1 PF03029.17 EPE28382.1 - 1.3e-77 260.9 0.3 1.8e-77 260.4 0.0 1.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 EPE28382.1 - 2.3e-05 23.5 0.1 5.8e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EPE28382.1 - 0.0014 18.7 0.0 0.027 14.6 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_31 PF13614.6 EPE28382.1 - 0.0024 17.8 0.0 2.7 7.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain CLP1_P PF16575.5 EPE28382.1 - 0.0037 17.1 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_10 PF12846.7 EPE28382.1 - 0.017 14.1 0.0 0.031 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.12 EPE28382.1 - 0.024 13.9 0.0 0.062 12.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Fer4_NifH PF00142.18 EPE28382.1 - 0.066 12.7 0.4 0.31 10.4 0.4 2.0 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_18 PF13238.6 EPE28382.1 - 0.11 13.0 1.3 0.31 11.6 0.1 2.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EPE28382.1 - 0.14 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.10 EPE28382.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 WD40 PF00400.32 EPE28383.1 - 1.1e-13 51.4 0.9 0.014 16.2 0.3 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE28383.1 - 0.00034 20.9 0.0 1.1 9.6 0.0 3.6 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain CAS_C PF12026.8 EPE28383.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain SNF2_N PF00176.23 EPE28384.1 - 1.7e-70 237.5 0.0 2.3e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EPE28384.1 - 9e-17 60.8 0.0 1.8e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EPE28384.1 - 4.6e-14 52.7 0.0 3.5e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EPE28384.1 - 2.8e-10 39.9 8.7 6.4e-10 38.7 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE28384.1 - 1.1e-08 35.2 8.1 1.1e-08 35.2 8.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EPE28384.1 - 1.5e-07 31.2 6.7 1.5e-07 31.2 6.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE28384.1 - 6.1e-07 29.4 2.4 6.1e-07 29.4 2.4 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EPE28384.1 - 2.1e-06 27.6 8.0 4.1e-06 26.6 8.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EPE28384.1 - 2.4e-06 27.3 9.9 5e-06 26.3 9.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPE28384.1 - 8.3e-06 26.0 6.6 2.1e-05 24.7 6.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EPE28384.1 - 7.5e-05 22.8 7.0 0.00015 21.8 7.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EPE28384.1 - 0.00017 21.4 9.6 0.00035 20.4 9.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EPE28384.1 - 0.00073 19.2 4.5 0.0026 17.5 4.5 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-Nse PF11789.8 EPE28384.1 - 0.0025 17.6 5.8 0.0067 16.2 5.5 1.9 2 0 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 EPE28384.1 - 0.0064 16.6 0.1 0.14 12.3 0.0 2.9 2 0 0 2 2 2 1 U-box domain zf-ANAPC11 PF12861.7 EPE28384.1 - 0.007 16.4 1.3 0.017 15.2 1.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EPE28384.1 - 0.24 11.5 7.4 0.8 9.9 7.4 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EPE28384.1 - 2 8.3 4.7 5.5 6.9 4.7 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HET PF06985.11 EPE28385.1 - 6.1e-34 117.5 0.1 9.2e-34 116.9 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PhoLip_ATPase_C PF16212.5 EPE28386.1 - 0.0021 17.9 0.3 0.0027 17.5 0.3 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal MARVEL PF01284.23 EPE28386.1 - 0.0023 18.0 4.0 0.0043 17.1 4.0 1.5 1 1 0 1 1 1 1 Membrane-associating domain HlyIII PF03006.20 EPE28386.1 - 0.011 15.4 0.7 0.015 15.0 0.7 1.1 1 0 0 1 1 1 0 Haemolysin-III related DUF3810 PF12725.7 EPE28386.1 - 0.062 12.6 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Chromate_transp PF02417.15 EPE28386.1 - 1.1 9.4 8.1 1.8 8.7 8.1 1.3 1 0 0 1 1 1 0 Chromate transporter AA_permease_2 PF13520.6 EPE28386.1 - 1.5 7.6 10.0 3.1 6.5 9.6 1.6 1 1 0 1 1 1 0 Amino acid permease Chitin_synth_1 PF01644.17 EPE28387.1 - 1e-77 259.7 0.1 1.5e-77 259.1 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EPE28387.1 - 2.5e-27 94.6 0.0 5.9e-27 93.4 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EPE28387.1 - 3.7e-24 85.3 2.7 3.4e-21 75.5 0.0 2.3 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EPE28387.1 - 2.9e-07 30.6 0.4 2.9e-07 30.6 0.4 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Abhydrolase_1 PF00561.20 EPE28389.1 - 0.00021 21.0 0.1 0.0018 18.0 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE28389.1 - 0.0018 17.6 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EPE28389.1 - 0.0019 18.1 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase LIP PF03583.14 EPE28389.1 - 0.021 14.2 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 Secretory lipase Peptidase_S9 PF00326.21 EPE28389.1 - 0.028 13.9 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pkinase PF00069.25 EPE28390.1 - 3.3e-45 154.5 0.0 5.3e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 EPE28390.1 - 7.4e-28 97.0 0.1 7.5e-09 36.1 0.0 5.0 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE28390.1 - 2.1e-25 88.7 6.8 3.7e-05 24.2 0.1 7.4 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 EPE28390.1 - 3.1e-24 85.7 0.0 5e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 EPE28390.1 - 2.2e-20 70.5 3.3 0.061 13.9 0.0 8.7 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 EPE28390.1 - 7.5e-18 64.1 7.8 0.013 15.9 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EPE28390.1 - 4.4e-17 61.9 5.4 0.00016 21.9 0.1 6.4 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Kinase-like PF14531.6 EPE28390.1 - 0.03 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF1077 PF06417.12 EPE28391.1 - 1.7e-49 166.7 3.2 2.2e-49 166.4 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.20 EPE28392.1 - 7.1e-122 407.6 8.7 8.7e-122 407.3 8.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EPE28392.1 - 5.2e-56 189.2 9.0 6.9e-56 188.8 0.2 3.4 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EPE28392.1 - 1.8e-13 50.7 7.5 7.7e-05 23.0 0.2 5.0 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 EPE28392.1 - 7.8e-11 41.3 1.6 0.018 15.2 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 EPE28392.1 - 0.0015 19.0 2.5 1.3 9.6 0.2 5.2 3 1 2 5 5 5 1 HEAT-like repeat CLASP_N PF12348.8 EPE28392.1 - 0.0022 17.6 2.9 1.3 8.5 0.1 3.1 3 0 0 3 3 3 2 CLASP N terminal Atx10homo_assoc PF09759.9 EPE28392.1 - 0.005 16.8 0.0 4.6 7.3 0.0 3.9 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EPE28392.1 - 0.026 14.6 1.0 4.6 7.4 0.0 4.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 EPE28392.1 - 0.13 12.0 1.0 21 4.8 0.1 2.9 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) FKBP_C PF00254.28 EPE28393.1 - 8.6e-28 96.5 0.0 1e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF3277 PF11681.8 EPE28393.1 - 0.19 11.6 0.5 8.5 6.3 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3277) ThiF PF00899.21 EPE28394.1 - 3.3e-108 360.7 0.0 9e-75 251.2 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EPE28394.1 - 1.2e-93 313.7 1.9 2e-93 313.0 1.9 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EPE28394.1 - 6.8e-34 116.4 0.1 1.6e-33 115.3 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 EPE28394.1 - 7e-27 93.4 0.0 1.9e-26 92.0 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EPE28394.1 - 2.8e-23 81.9 0.3 7.4e-23 80.5 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle GST_N_2 PF13409.6 EPE28395.1 - 1.3e-22 79.8 0.0 3.3e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPE28395.1 - 3e-14 52.8 0.0 1e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EPE28395.1 - 1.1e-05 25.6 0.1 3.9e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EPE28395.1 - 3.2e-05 24.2 0.0 0.0015 18.9 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EPE28395.1 - 0.00045 20.4 0.1 0.00098 19.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EPE28395.1 - 0.021 15.4 0.0 0.036 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF5601 PF18151.1 EPE28395.1 - 0.12 12.6 0.3 0.47 10.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) Glyco_hydro_61 PF03443.14 EPE28396.1 - 1.1e-55 188.8 0.0 2.7e-55 187.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Glyco_hydro_17 PF00332.18 EPE28397.1 - 1.9e-08 34.3 1.1 2.7e-08 33.8 1.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Wyosine_form PF08608.12 EPE28400.1 - 1.7e-22 79.5 0.0 3.7e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 EPE28400.1 - 3.7e-22 79.5 0.1 2.6e-21 76.7 0.0 2.5 2 0 0 2 2 2 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 EPE28400.1 - 1.7e-09 38.0 0.1 1.7e-08 34.8 0.1 2.4 1 1 0 1 1 1 1 Flavodoxin Apolipoprotein PF01442.18 EPE28401.1 - 0.0061 16.5 0.9 0.012 15.5 0.9 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Golgin_A5 PF09787.9 EPE28401.1 - 0.0071 15.9 1.8 0.0071 15.9 1.8 1.9 2 1 0 2 2 2 1 Golgin subfamily A member 5 Med9 PF07544.13 EPE28401.1 - 0.015 15.4 3.3 0.03 14.4 2.5 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FAR1 PF03101.15 EPE28401.1 - 0.065 13.9 0.2 0.17 12.6 0.2 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain XLF PF09302.11 EPE28401.1 - 0.09 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component TPR_MLP1_2 PF07926.12 EPE28401.1 - 0.18 11.9 6.1 0.18 11.8 3.9 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein COG2 PF06148.11 EPE28401.1 - 0.21 11.7 1.9 0.46 10.6 1.9 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Fzo_mitofusin PF04799.13 EPE28401.1 - 0.27 10.8 2.7 0.48 10.0 0.4 2.1 2 0 0 2 2 2 0 fzo-like conserved region Mvb12 PF09452.10 EPE28401.1 - 0.34 11.4 3.1 0.24 11.9 0.5 2.1 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 KfrA_N PF11740.8 EPE28401.1 - 3.3 8.4 8.0 0.61 10.8 0.9 2.8 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term OmpH PF03938.14 EPE28401.1 - 4.2 7.7 8.4 1.1 9.6 2.0 2.7 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF4139 PF13598.6 EPE28402.1 - 8.5e-35 120.4 0.0 9.7e-34 116.9 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 EPE28402.1 - 1.1e-24 86.7 0.6 1.1e-24 86.7 0.6 4.2 4 1 0 4 4 4 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.6 EPE28402.1 - 0.0011 19.7 0.7 0.0011 19.7 0.7 2.7 2 0 0 2 2 2 1 Nucleoporin FG repeat region DUF1843 PF08898.10 EPE28402.1 - 0.087 13.3 0.5 0.29 11.6 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) End3 PF12761.7 EPE28402.1 - 0.62 10.2 10.5 0.031 14.5 3.2 2.3 2 1 1 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 DUF4419 PF14388.6 EPE28403.1 - 8.8e-114 380.0 0.0 1.1e-113 379.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) FAD_binding_3 PF01494.19 EPE28404.1 - 2.4e-19 69.8 0.0 3.7e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.18 EPE28404.1 - 7.2e-11 41.6 2.8 1.2e-10 40.9 2.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.24 EPE28404.1 - 3.2e-08 33.6 0.2 0.0057 16.3 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE28404.1 - 9e-05 21.8 0.0 0.00042 19.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE28404.1 - 0.00034 21.1 1.2 0.003 18.1 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE28404.1 - 0.17 12.2 0.1 0.39 11.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3Beta_HSD PF01073.19 EPE28405.1 - 4.1e-08 32.6 0.0 1.1e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPE28405.1 - 1.6e-06 27.8 0.1 4.7e-06 26.2 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE28405.1 - 3.4e-05 23.4 0.0 4.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPE28405.1 - 6.1e-05 22.3 0.0 0.21 10.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EPE28405.1 - 8.1e-05 22.6 0.0 0.00022 21.2 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPE28405.1 - 0.00021 20.9 0.0 0.00063 19.4 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EPE28405.1 - 0.0074 15.8 0.0 0.028 13.9 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EPE28405.1 - 0.0095 15.9 0.1 0.38 10.6 0.0 2.5 3 0 0 3 3 3 1 KR domain RmlD_sub_bind PF04321.17 EPE28405.1 - 0.089 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain CotJB PF12652.7 EPE28407.1 - 0.028 14.6 0.2 9.9 6.5 0.1 2.6 2 0 0 2 2 2 0 CotJB protein MIP-T3_C PF17749.1 EPE28407.1 - 0.16 12.0 9.4 0.17 11.8 5.5 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DivIC PF04977.15 EPE28407.1 - 7.5 6.4 10.3 1.8 8.4 0.3 2.7 1 1 2 3 3 3 0 Septum formation initiator Metal_resist PF13801.6 EPE28407.1 - 8.3 6.6 10.4 15 5.8 9.3 1.9 1 1 1 2 2 2 0 Heavy-metal resistance DUF3425 PF11905.8 EPE28408.1 - 1.1e-17 64.2 0.0 2.8e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) adh_short PF00106.25 EPE28409.1 - 3.5e-12 46.2 0.0 2.9e-10 39.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE28409.1 - 3e-09 36.8 0.0 3.8e-08 33.2 0.0 2.2 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE28409.1 - 0.057 13.3 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 KR domain MiaE_2 PF13794.6 EPE28409.1 - 0.2 11.4 0.7 5.6 6.6 0.1 2.1 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like FAM163 PF15069.6 EPE28410.1 - 0.0076 16.7 0.6 0.02 15.4 0.0 1.9 2 0 0 2 2 2 1 FAM163 family Lipase_GDSL_2 PF13472.6 EPE28412.1 - 4.5e-21 76.0 0.0 7.5e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE28412.1 - 2e-13 50.8 0.0 3.5e-13 50.0 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Methyltransf_25 PF13649.6 EPE28413.1 - 5.9e-14 52.5 0.0 2.3e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE28413.1 - 2.1e-13 50.7 0.0 5.3e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE28413.1 - 3.6e-11 43.1 0.0 6.1e-11 42.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE28413.1 - 4e-11 42.7 0.0 2.2e-09 37.0 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EPE28413.1 - 6.4e-08 33.3 0.0 1.4e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE28413.1 - 1e-06 28.7 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPE28413.1 - 6.7e-06 25.7 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 EPE28413.1 - 0.027 14.0 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.7 EPE28413.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NUC153 PF08159.12 EPE28414.1 - 1.2e-10 41.0 9.9 1.6e-09 37.4 0.0 3.6 3 0 0 3 3 3 2 NUC153 domain EamA PF00892.20 EPE28415.1 - 6.8e-20 71.6 35.1 9.1e-15 55.0 5.4 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF4477 PF14780.6 EPE28416.1 - 0.055 13.1 0.1 0.07 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) HET PF06985.11 EPE28418.1 - 2.8e-09 37.5 0.0 4.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Na_Ca_ex PF01699.24 EPE28423.1 - 1.9e-40 138.3 33.4 1e-21 77.5 13.1 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein UPF0560 PF10577.9 EPE28423.1 - 1.8 7.0 5.6 2.5 6.5 5.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SNF2_N PF00176.23 EPE28424.1 - 2.5e-57 194.2 0.1 2.5e-57 194.2 0.1 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE28424.1 - 1.6e-09 38.1 0.0 4.2e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EPE28424.1 - 1.9e-07 30.8 7.2 4.1e-07 29.8 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPE28424.1 - 9.8e-06 25.6 6.7 2.2e-05 24.5 6.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EPE28424.1 - 7.2e-05 22.7 4.8 0.00016 21.6 4.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EPE28424.1 - 0.00012 22.0 8.0 0.00023 21.0 8.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EPE28424.1 - 0.00012 21.8 5.1 0.00021 21.1 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE28424.1 - 0.00082 19.7 7.7 0.0018 18.6 7.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPE28424.1 - 0.0011 18.7 9.0 0.0034 17.2 9.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-4CXXC_R1 PF10497.9 EPE28424.1 - 0.055 13.7 2.3 0.19 12.0 2.3 1.9 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_10 PF16685.5 EPE28424.1 - 0.26 11.5 4.8 0.51 10.5 3.3 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-Nse PF11789.8 EPE28424.1 - 0.29 11.0 3.9 0.72 9.7 3.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 EPE28424.1 - 0.68 10.3 3.9 2 8.7 3.9 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EPE28424.1 - 0.99 9.3 5.4 2.2 8.2 5.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 NARP1 PF12569.8 EPE28424.1 - 1.5 7.6 14.8 3 6.7 11.6 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 WDCP PF15390.6 EPE28424.1 - 1.5 7.1 3.8 2.7 6.3 3.8 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Zn-ribbon_8 PF09723.10 EPE28424.1 - 2.1 8.5 6.8 0.77 9.9 3.6 2.0 2 0 0 2 2 1 0 Zinc ribbon domain DUF4778 PF16008.5 EPE28424.1 - 3.8 7.5 16.0 0.058 13.5 7.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) Peptidase_M24 PF00557.24 EPE28425.1 - 1.7e-10 40.9 0.0 2e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Ank_4 PF13637.6 EPE28427.1 - 3.3e-17 62.6 0.3 1.2e-08 35.3 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE28427.1 - 1.3e-13 51.3 0.0 7.4e-12 45.7 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE28427.1 - 4.8e-13 48.0 0.0 2.7e-05 24.2 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EPE28427.1 - 6e-13 48.7 0.1 3.2e-11 43.2 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EPE28427.1 - 9e-13 48.0 0.2 6.9e-06 26.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat ATP-grasp_4 PF13535.6 EPE28428.1 - 1.9e-13 50.3 0.0 6.3e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_N PF18130.1 EPE28428.1 - 1.1e-09 38.7 0.0 3.5e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp N-terminal domain Dala_Dala_lig_C PF07478.13 EPE28428.1 - 1e-06 28.5 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 EPE28428.1 - 0.2 11.2 0.0 0.41 10.1 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Cys_Met_Meta_PP PF01053.20 EPE28429.1 - 1.8e-45 155.1 0.0 2e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Phage_ABA_S PF18066.1 EPE28429.1 - 0.14 12.9 0.0 0.23 12.2 0.0 1.5 1 1 0 1 1 1 0 Phage ABA sandwich domain Cys_Met_Meta_PP PF01053.20 EPE28430.1 - 3.3e-16 58.8 0.0 4.2e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme NAS PF03059.16 EPE28431.1 - 1.8e-29 103.0 0.0 2.2e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_31 PF13847.6 EPE28431.1 - 0.0002 21.2 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE28431.1 - 0.043 14.5 0.0 0.077 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy PF03171.20 EPE28432.1 - 1.1e-14 54.8 0.0 1.7e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EPE28432.1 - 2e-08 35.0 0.0 3.5e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DAO PF01266.24 EPE28433.1 - 5.4e-45 154.5 0.0 6.3e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EPE28433.1 - 0.00029 20.9 0.6 0.012 15.5 0.1 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EPE28433.1 - 0.00061 18.6 0.0 0.26 9.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 EPE28433.1 - 0.0011 18.3 0.1 0.57 9.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EPE28433.1 - 0.0032 16.8 0.0 0.93 8.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EPE28433.1 - 0.0034 16.7 0.0 0.017 14.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE28433.1 - 0.0037 17.4 0.1 0.0089 16.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPE28433.1 - 0.004 16.3 0.0 0.067 12.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 EPE28433.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family MCRA PF06100.11 EPE28433.1 - 0.13 11.1 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 MCRA family Cys_Met_Meta_PP PF01053.20 EPE28434.1 - 2.9e-111 371.7 0.0 3.3e-111 371.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EPE28434.1 - 3.2e-08 33.0 0.0 4.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EPE28434.1 - 0.0027 17.1 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 EPE28434.1 - 0.0035 16.2 0.0 0.0051 15.7 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 EPE28434.1 - 0.086 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase AMP-binding PF00501.28 EPE28435.1 - 1.4e-147 491.7 0.0 1.9e-73 247.5 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EPE28435.1 - 5.4e-92 308.9 0.0 5.7e-31 107.7 0.5 4.3 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.25 EPE28435.1 - 4.2e-16 59.1 0.2 1.6e-06 28.3 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site P5CR_dimer PF14748.6 EPE28435.1 - 3.4e-15 56.1 0.6 9.9e-15 54.7 0.6 1.9 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation AMP-binding_C PF13193.6 EPE28435.1 - 1.1e-10 42.3 0.0 0.00012 23.0 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain F420_oxidored PF03807.17 EPE28435.1 - 2.5e-07 31.2 0.0 6.7e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EPE28435.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2OG-FeII_Oxy PF03171.20 EPE28436.1 - 2.8e-15 56.6 0.0 6.1e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EPE28436.1 - 3.8e-06 27.6 0.0 6.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Abhydrolase_1 PF00561.20 EPE28437.1 - 1.2e-38 133.3 0.0 1.5e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE28437.1 - 2.1e-06 28.5 0.2 3e-06 28.0 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE28437.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 EPE28437.1 - 0.087 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DIOX_N PF14226.6 EPE28438.1 - 1.7e-20 73.9 0.0 4.1e-20 72.7 0.0 1.7 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPE28438.1 - 1.2e-12 48.1 0.0 3.6e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 EPE28439.1 - 8e-73 245.4 0.0 1.1e-72 245.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EPE28439.1 - 3.2e-23 82.1 0.7 4.7e-23 81.6 0.1 1.5 2 0 0 2 2 2 1 Condensation domain AMP-binding_C PF13193.6 EPE28439.1 - 2e-08 35.1 0.1 1.2e-07 32.6 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Condensation PF00668.20 EPE28440.1 - 1.1e-87 294.7 0.1 1.5e-87 294.2 0.1 1.1 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 EPE28440.1 - 1.2e-68 231.7 0.0 1.7e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EPE28440.1 - 5.7e-11 42.6 0.1 2.2e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPE28440.1 - 6e-09 36.8 0.0 6e-08 33.6 0.0 2.8 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Thioesterase PF00975.20 EPE28441.1 - 1.7e-09 38.2 0.0 2.3e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EPE28441.1 - 0.00028 21.6 0.5 0.00033 21.3 0.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.16 EPE28442.1 - 3.4e-24 85.4 25.6 3.4e-24 85.4 25.6 1.7 3 0 0 3 3 3 1 Major Facilitator Superfamily Prominin PF05478.11 EPE28442.1 - 0.16 9.9 1.7 0.22 9.4 1.7 1.1 1 0 0 1 1 1 0 Prominin MFS_1 PF07690.16 EPE28443.1 - 3.6e-33 114.9 16.1 3.6e-33 114.9 16.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_4 PF01565.23 EPE28444.1 - 1.2e-22 80.1 1.0 1.2e-22 80.1 1.0 1.7 2 0 0 2 2 2 1 FAD binding domain ALO PF04030.14 EPE28444.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase BBE PF08031.12 EPE28444.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like Glyco_hydro_43 PF04616.14 EPE28445.1 - 6.6e-33 114.2 4.3 7.3e-33 114.1 3.5 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EPE28445.1 - 3.3e-23 82.5 1.1 7.1e-23 81.4 0.1 1.9 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain Esterase_phd PF10503.9 EPE28446.1 - 1.7e-18 66.9 0.3 2.7e-18 66.3 0.3 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EPE28446.1 - 5.5e-11 42.3 1.8 8e-11 41.8 1.8 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 EPE28446.1 - 0.011 14.6 0.4 0.019 13.9 0.0 1.4 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE28446.1 - 0.06 13.2 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EPE28446.1 - 0.081 12.6 1.0 0.13 11.9 0.6 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ribosomal_L28 PF00830.19 EPE28448.1 - 2e-19 69.5 1.3 3.4e-19 68.8 1.3 1.3 1 0 0 1 1 1 1 Ribosomal L28 family MFS_1 PF07690.16 EPE28449.1 - 4.2e-42 144.3 59.0 1.2e-40 139.5 42.8 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE28449.1 - 2e-10 40.1 10.4 2e-10 40.1 10.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter GATase PF00117.28 EPE28450.1 - 5.3e-14 52.4 0.0 1e-13 51.5 0.0 1.4 1 1 1 2 2 2 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EPE28450.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain S1-P1_nuclease PF02265.16 EPE28451.1 - 1.3e-66 225.1 0.0 1.4e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease RsfS PF02410.15 EPE28452.1 - 3.7e-15 56.2 0.0 4.1e-13 49.6 0.0 2.6 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation TPR_8 PF13181.6 EPE28452.1 - 0.0043 17.2 0.1 0.015 15.5 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPE28452.1 - 0.042 14.7 5.3 0.043 14.6 0.2 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EPE28452.1 - 0.082 13.6 0.1 0.27 11.9 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 EPE28452.1 - 0.11 12.7 0.6 0.44 10.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Amidase PF01425.21 EPE28453.1 - 1.2e-81 275.0 0.1 1.5e-81 274.7 0.1 1.2 1 0 0 1 1 1 1 Amidase PBD PF00786.28 EPE28456.1 - 0.034 14.5 0.0 0.11 12.9 0.0 2.0 1 0 0 1 1 1 0 P21-Rho-binding domain DUF612 PF04747.12 EPE28456.1 - 0.034 13.3 1.8 0.051 12.7 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF612 DUF1003 PF06210.11 EPE28456.1 - 0.9 9.7 4.0 30 4.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Angiomotin_C PF12240.8 EPE28456.1 - 2.5 7.6 11.7 0.36 10.4 7.6 1.7 2 0 0 2 2 2 0 Angiomotin C terminal YabA PF06156.13 EPE28458.1 - 0.014 16.0 8.8 0.024 15.3 8.5 1.5 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 EPE28458.1 - 0.34 11.4 7.6 0.73 10.3 7.6 1.5 1 0 0 1 1 1 0 Cell division protein ZapB SOAR PF16533.5 EPE28458.1 - 0.35 10.9 5.9 0.3 11.1 3.3 1.9 1 1 1 2 2 2 0 STIM1 Orai1-activating region CENP-H PF05837.12 EPE28458.1 - 0.89 10.0 10.9 1.6 9.2 10.8 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Mod_r PF07200.13 EPE28458.1 - 1 9.5 10.2 1.5 8.9 10.2 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Sec20 PF03908.13 EPE28458.1 - 1.7 8.6 4.9 3.1 7.8 4.9 1.4 1 0 0 1 1 1 0 Sec20 SOBP PF15279.6 EPE28458.1 - 2 9.0 16.4 3.6 8.1 16.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein SlyX PF04102.12 EPE28458.1 - 2.1 9.1 7.0 10 6.8 4.6 2.7 1 1 1 2 2 2 0 SlyX DUF3450 PF11932.8 EPE28458.1 - 4.3 6.6 13.6 3 7.1 11.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4407 PF14362.6 EPE28458.1 - 4.8 6.5 7.8 8.6 5.6 7.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fungal_trans PF04082.18 EPE28461.1 - 5.9e-21 74.7 0.0 1.1e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE28461.1 - 4.1e-06 26.8 15.4 7.3e-06 26.0 15.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1179 PF06678.11 EPE28461.1 - 0.03 14.3 0.3 0.06 13.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) ThiF PF00899.21 EPE28463.1 - 4e-11 42.7 0.3 8.7e-09 35.1 0.1 2.4 2 1 0 2 2 2 2 ThiF family E1_4HB PF16191.5 EPE28463.1 - 0.067 13.4 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle Rib_5-P_isom_A PF06026.14 EPE28464.1 - 1.1e-45 155.3 0.0 1.5e-44 151.7 0.0 2.2 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 EPE28464.1 - 0.021 14.7 0.0 4 7.3 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain ECH_1 PF00378.20 EPE28465.1 - 1.5e-47 162.0 0.0 2.1e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPE28465.1 - 1.3e-24 87.4 0.0 7.4e-24 84.8 0.0 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF3005 PF11448.8 EPE28465.1 - 0.15 12.1 0.1 20 5.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3005) ECH_1 PF00378.20 EPE28466.1 - 3.8e-50 170.5 0.0 4.8e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPE28466.1 - 2.3e-25 89.8 0.0 9.1e-23 81.3 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EPE28466.1 - 0.014 15.3 0.3 4.8 7.1 0.2 2.2 2 0 0 2 2 2 0 Peptidase family S49 RHH_3 PF12651.7 EPE28466.1 - 0.23 11.4 0.9 1.6 8.8 0.1 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix domain RVT_1 PF00078.27 EPE28468.1 - 2e-05 24.2 0.0 4.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ATP-synt_E_2 PF08112.11 EPE28468.1 - 0.0047 17.2 0.4 0.077 13.3 0.1 2.6 2 0 0 2 2 2 1 ATP synthase epsilon subunit LIFR_D2 PF17971.1 EPE28468.1 - 0.049 13.8 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor D2 domain Pox_Ag35 PF03286.14 EPE28468.1 - 0.056 13.2 0.4 0.11 12.3 0.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nfu_N PF08712.11 EPE28468.1 - 0.1 12.6 0.3 0.97 9.5 0.1 2.5 2 0 0 2 2 2 0 Scaffold protein Nfu/NifU N terminal p450 PF00067.22 EPE28469.1 - 2.7e-15 56.1 0.1 4.5e-13 48.8 0.0 3.3 2 2 0 2 2 2 2 Cytochrome P450 HsbA PF12296.8 EPE28470.1 - 3.9e-18 66.0 2.0 6.3e-18 65.4 2.0 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF1343 PF07075.11 EPE28470.1 - 0.12 11.7 0.2 0.16 11.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1343) DUF2756 PF10956.8 EPE28470.1 - 0.17 12.4 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) CTP_transf_1 PF01148.20 EPE28471.1 - 1.3e-79 267.7 27.0 1.8e-79 267.2 27.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Asp PF00026.23 EPE28471.1 - 0.00013 21.5 0.0 0.013 15.0 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic aspartyl protease DUF3636 PF12331.8 EPE28472.1 - 1.6e-50 170.8 0.9 3e-50 169.9 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 EPE28472.1 - 0.059 11.9 8.4 0.26 9.8 5.0 2.6 2 1 0 2 2 2 0 DNA damage checkpoint protein Golgin_A5 PF09787.9 EPE28472.1 - 0.72 9.3 12.8 0.55 9.6 11.2 1.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 CCDC106 PF15794.5 EPE28472.1 - 2.1 8.0 16.1 0.82 9.3 12.0 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 Phage_TTP_12 PF16461.5 EPE28473.1 - 0.011 15.4 0.2 0.016 14.9 0.2 1.2 1 0 0 1 1 1 0 Lambda phage tail tube protein, TTP zf-C3HC4_3 PF13920.6 EPE28477.1 - 2.7e-05 23.9 7.2 5.8e-05 22.9 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE28477.1 - 7.5e-05 23.0 11.5 7.5e-05 23.0 11.5 1.8 2 0 0 2 2 2 1 Ring finger domain Baculo_IE-1 PF05290.11 EPE28477.1 - 0.0028 17.6 1.9 0.0058 16.6 1.9 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.6 EPE28477.1 - 0.005 16.8 8.9 0.005 16.8 8.9 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 EPE28477.1 - 0.016 15.0 5.4 0.016 15.0 5.4 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 EPE28477.1 - 0.026 14.4 9.9 0.026 14.4 9.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE28477.1 - 0.11 12.3 15.9 0.5 10.3 11.0 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE28477.1 - 2.6 8.0 13.5 0.18 11.7 7.9 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 E1-E2_ATPase PF00122.20 EPE28479.1 - 6e-19 68.3 0.2 5.7e-18 65.1 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EPE28479.1 - 2.1e-13 51.1 0.6 9.7e-07 29.3 0.5 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPE28479.1 - 0.00021 21.3 0.0 0.01 15.9 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EPE28479.1 - 0.034 13.9 1.1 0.099 12.4 0.1 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4059 PF13268.6 EPE28479.1 - 0.078 13.4 2.1 12 6.4 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) PLDc_2 PF13091.6 EPE28480.1 - 7.4e-15 55.0 0.1 1e-05 25.4 0.1 3.6 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 EPE28480.1 - 1.9e-13 49.9 3.4 7.4e-07 29.1 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif NB PF04159.13 EPE28481.1 - 0.018 15.1 0.3 2.9 8.0 0.0 2.2 1 1 1 2 2 2 0 NB glycoprotein PKD_channel PF08016.12 EPE28483.1 - 4e-08 32.4 20.6 2.1e-06 26.7 20.6 2.3 1 1 0 1 1 1 1 Polycystin cation channel DHHC PF01529.20 EPE28483.1 - 0.91 9.6 11.6 0.27 11.3 1.2 2.9 1 1 1 2 2 2 0 DHHC palmitoyltransferase Ac76 PF05814.11 EPE28483.1 - 5.4 7.1 10.3 6.8 6.8 0.8 3.2 2 0 0 2 2 2 0 Orf76 (Ac76) Sigma_reg_N PF13800.6 EPE28483.1 - 6.9 7.0 7.4 8.1 6.8 1.4 2.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal peroxidase PF00141.23 EPE28484.1 - 6.8e-16 58.7 0.0 1.1e-15 57.9 0.0 1.4 1 1 0 1 1 1 1 Peroxidase GMC_oxred_N PF00732.19 EPE28486.1 - 2.7e-66 224.0 0.0 4.4e-66 223.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE28486.1 - 5.3e-37 127.5 0.1 8.7e-37 126.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EPE28486.1 - 8.5e-05 22.7 0.0 0.00026 21.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE28486.1 - 0.00021 20.5 0.1 0.00051 19.2 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 EPE28486.1 - 0.0069 16.6 0.1 0.032 14.5 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.12 EPE28486.1 - 0.01 14.9 0.1 0.019 14.0 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 EPE28486.1 - 0.018 14.6 0.1 0.11 12.1 0.0 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EPE28486.1 - 0.019 13.7 0.0 0.036 12.8 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 EPE28486.1 - 0.045 13.0 0.1 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DNA_repr_REX1B PF14966.6 EPE28487.1 - 0.047 14.3 0.7 25 5.6 0.0 3.5 2 1 0 3 3 3 0 DNA repair REX1-B CC2-LZ PF16516.5 EPE28487.1 - 0.12 12.8 1.0 0.43 11.0 0.5 2.2 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Tup_N PF08581.10 EPE28487.1 - 0.2 12.0 2.8 0.25 11.7 1.0 2.1 2 0 0 2 2 2 0 Tup N-terminal DUF4201 PF13870.6 EPE28487.1 - 4.5 7.0 9.1 0.51 10.0 0.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) MAPEG PF01124.18 EPE28489.1 - 1.5e-16 60.4 0.7 1.9e-16 60.1 0.7 1.2 1 0 0 1 1 1 1 MAPEG family Mersacidin PF16934.5 EPE28489.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) BTP PF05232.12 EPE28489.1 - 0.28 11.3 0.3 0.28 11.3 0.3 1.8 3 0 0 3 3 3 0 Chlorhexidine efflux transporter GLTP PF08718.11 EPE28491.1 - 4.2e-47 160.2 0.0 5.4e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) CCT PF06203.14 EPE28492.1 - 0.3 11.2 3.1 0.87 9.7 3.1 1.7 1 0 0 1 1 1 0 CCT motif Abhydrolase_4 PF08386.10 EPE28493.1 - 2.9e-14 53.0 0.0 6.9e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 EPE28493.1 - 9e-13 48.5 0.3 9.9e-09 35.2 0.1 2.8 2 1 0 2 2 2 2 alpha/beta hydrolase fold Root_cap PF06830.11 EPE28493.1 - 0.017 15.2 0.8 0.055 13.6 0.8 1.8 1 0 0 1 1 1 0 Root cap Methyltransf_10 PF05971.12 EPE28494.1 - 2.6e-64 217.4 0.0 3.8e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase PrmA PF06325.13 EPE28494.1 - 1.7e-07 30.9 0.0 2.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EPE28494.1 - 3.3e-05 23.5 0.0 9.6e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EPE28494.1 - 0.0011 18.7 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE28494.1 - 0.0033 18.1 0.0 0.042 14.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 EPE28494.1 - 0.0035 17.0 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 EPE28494.1 - 0.028 15.1 0.0 0.13 13.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Macro PF01661.21 EPE28495.1 - 8.2e-40 135.5 0.1 1.3e-39 134.9 0.1 1.3 1 0 0 1 1 1 1 Macro domain tRNA-synt_1c PF00749.21 EPE28496.1 - 9.9e-103 343.3 0.0 1.4e-102 342.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EPE28496.1 - 1.4e-28 99.9 0.1 4.2e-28 98.4 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribosomal_S17e PF00833.18 EPE28497.1 - 4.5e-61 204.2 0.7 5.5e-61 203.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal S17 RPAP2_Rtr1 PF04181.13 EPE28498.1 - 2.6e-23 82.1 0.0 4.8e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_9 PF14604.6 EPE28499.1 - 8.2e-10 38.4 0.4 2.1e-09 37.1 0.3 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EPE28499.1 - 2.1e-09 36.8 0.1 5.5e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EPE28499.1 - 1.1e-08 34.6 0.0 2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DNA_pol_phi PF04931.13 EPE28499.1 - 5.5 5.0 9.3 9.4 4.2 9.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi Acetyltransf_1 PF00583.25 EPE28500.1 - 8.6e-06 26.0 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pho86 PF11124.8 EPE28500.1 - 0.00013 21.6 0.2 0.00021 20.9 0.2 1.3 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Acetyltransf_CG PF14542.6 EPE28500.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Amidase PF01425.21 EPE28501.1 - 5.1e-118 394.9 0.0 1.5e-117 393.4 0.0 1.7 2 1 0 2 2 2 1 Amidase DUF3107 PF11305.8 EPE28502.1 - 0.049 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3107) ASFV_J13L PF05568.11 EPE28502.1 - 2.5 7.8 8.9 3.3 7.4 7.0 2.2 3 0 0 3 3 3 0 African swine fever virus J13L protein KH_9 PF17904.1 EPE28503.1 - 0.065 13.6 0.0 0.068 13.6 0.0 1.1 1 0 0 1 1 1 0 FMRP KH0 domain Fip1 PF05182.13 EPE28504.1 - 4.7e-20 70.8 1.3 9.7e-20 69.8 1.3 1.6 1 0 0 1 1 1 1 Fip1 motif CDC45 PF02724.14 EPE28504.1 - 4 5.6 8.4 4.1 5.6 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoporin_FG PF13634.6 EPE28505.1 - 2.6e-34 117.9 109.9 4.4e-14 53.1 31.3 4.7 2 1 3 5 5 5 4 Nucleoporin FG repeat region Glyco_hydro_3 PF00933.21 EPE28505.1 - 0.017 14.5 0.1 0.033 13.6 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain GAT PF03127.14 EPE28505.1 - 0.068 13.5 0.7 77 3.7 0.1 3.3 3 0 0 3 3 3 0 GAT domain ING PF12998.7 EPE28505.1 - 0.13 12.9 0.7 0.24 12.0 0.0 1.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF2025 PF09634.10 EPE28506.1 - 0.039 14.0 0.3 1.5 8.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2025) WD40 PF00400.32 EPE28507.1 - 0.19 12.7 12.6 14 6.7 0.2 5.8 6 0 0 6 6 6 0 WD domain, G-beta repeat DAO PF01266.24 EPE28508.1 - 4.4e-35 121.9 0.3 5e-35 121.7 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EPE28508.1 - 0.00012 21.4 0.4 0.00031 20.1 0.1 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EPE28508.1 - 0.0017 18.6 1.7 0.0022 18.2 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE28508.1 - 0.0082 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE28508.1 - 0.039 13.2 0.0 0.079 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Toxin_28 PF08115.11 EPE28508.1 - 0.19 11.6 0.2 0.64 9.9 0.2 1.9 1 0 0 1 1 1 0 SFI toxin family 3Beta_HSD PF01073.19 EPE28509.1 - 1.2e-41 142.6 0.0 1.6e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPE28509.1 - 6.6e-25 88.0 0.0 8.6e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE28509.1 - 2.2e-16 60.2 0.0 8.5e-15 55.0 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPE28509.1 - 3.4e-09 36.3 0.0 0.00037 19.8 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EPE28509.1 - 4.3e-07 29.4 0.0 3.8e-05 23.0 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EPE28509.1 - 8e-07 28.4 0.0 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EPE28509.1 - 2.7e-05 24.1 0.0 3.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EPE28509.1 - 0.00088 18.8 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE28509.1 - 0.00099 19.1 0.1 0.0031 17.4 0.1 1.8 1 1 0 1 1 1 1 KR domain DapB_N PF01113.20 EPE28509.1 - 0.057 13.6 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short_C2 PF13561.6 EPE28509.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Pyr_redox_2 PF07992.14 EPE28510.1 - 1.5e-42 145.8 0.5 2.2e-42 145.3 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE28510.1 - 2.1e-16 60.2 2.8 2.5e-15 56.8 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EPE28510.1 - 1.1e-15 57.8 0.0 3.6e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain HI0933_like PF03486.14 EPE28510.1 - 4.8e-06 25.5 5.8 0.057 12.1 0.0 3.2 2 1 1 3 3 3 3 HI0933-like protein Pyr_redox_3 PF13738.6 EPE28510.1 - 5.1e-06 26.0 1.1 4.2e-05 22.9 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EPE28510.1 - 0.0001 22.7 2.8 0.33 11.4 0.1 2.7 3 0 0 3 3 2 2 Putative NAD(P)-binding XdhC_C PF13478.6 EPE28510.1 - 0.00029 21.3 0.2 0.021 15.3 0.0 2.7 2 1 0 2 2 2 1 XdhC Rossmann domain Lycopene_cycl PF05834.12 EPE28510.1 - 0.00064 18.9 4.3 0.28 10.2 0.0 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein 3HCDH_N PF02737.18 EPE28510.1 - 0.00087 19.2 1.4 0.0023 17.9 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EPE28510.1 - 0.0032 16.6 8.5 0.18 10.8 0.9 3.1 3 2 0 3 3 3 2 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 EPE28510.1 - 0.01 15.4 0.6 0.032 13.8 0.1 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 EPE28510.1 - 0.026 13.8 0.4 0.026 13.8 0.4 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EPE28510.1 - 0.026 13.9 0.2 0.072 12.4 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EPE28510.1 - 0.031 14.5 4.1 2.1 8.6 0.2 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 EPE28510.1 - 0.048 13.3 4.6 0.27 10.9 0.1 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EPE28510.1 - 0.12 12.7 0.9 0.45 10.8 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_3 PF01494.19 EPE28510.1 - 0.12 11.6 0.6 5.3 6.2 0.1 2.4 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 EPE28510.1 - 0.13 11.4 2.2 0.22 10.8 0.1 2.2 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 EPE28510.1 - 0.17 11.2 1.2 1.8 7.8 0.2 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 EPE28510.1 - 0.39 11.0 1.8 0.72 10.1 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 EPE28510.1 - 0.71 8.9 8.2 1 8.4 0.2 3.6 4 0 0 4 4 4 0 FAD binding domain Ald_Xan_dh_C2 PF02738.18 EPE28511.1 - 6.2e-206 685.1 0.5 8.9e-206 684.6 0.5 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EPE28511.1 - 8.4e-48 162.3 0.0 1.7e-47 161.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EPE28511.1 - 3.4e-33 113.9 0.1 1.7e-32 111.7 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 EPE28511.1 - 1.4e-29 102.7 0.0 3.5e-29 101.4 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 EPE28511.1 - 4.1e-29 100.4 0.0 8.8e-29 99.4 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 EPE28511.1 - 6e-08 32.5 0.1 6e-08 32.5 0.1 2.7 4 0 0 4 4 4 1 2Fe-2S iron-sulfur cluster binding domain p450 PF00067.22 EPE28512.1 - 2.3e-24 86.0 0.0 1.6e-21 76.6 0.1 2.9 1 1 0 2 2 2 1 Cytochrome P450 PhnG PF06754.12 EPE28512.1 - 0.11 12.4 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG Amino_oxidase PF01593.24 EPE28513.1 - 7.5e-21 74.9 0.0 5.8e-19 68.7 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPE28513.1 - 7.2e-11 42.2 0.1 1.4e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE28513.1 - 1.5e-05 24.7 0.7 0.0031 17.2 0.4 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE28513.1 - 2.5e-05 23.6 0.1 0.0032 16.7 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPE28513.1 - 0.00011 22.2 0.1 0.084 12.9 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 EPE28513.1 - 0.0043 15.8 0.0 2.1 7.0 0.0 2.4 3 0 0 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.21 EPE28513.1 - 0.039 13.2 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EPE28513.1 - 0.08 13.5 0.0 1.5 9.5 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE28513.1 - 0.12 11.5 0.2 0.27 10.2 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain V-SNARE PF05008.15 EPE28514.1 - 8.9e-21 74.1 2.3 8.9e-21 74.1 2.3 2.0 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EPE28514.1 - 1.6e-15 57.1 0.3 1.6e-15 57.1 0.3 2.6 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Acyl-CoA_dh_2 PF08028.11 EPE28514.1 - 0.024 14.9 1.9 0.039 14.2 1.3 1.6 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain DUF1542 PF07564.11 EPE28514.1 - 0.028 14.5 0.7 0.076 13.1 0.2 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) YqjK PF13997.6 EPE28514.1 - 0.087 13.1 2.7 0.79 10.0 0.2 2.5 2 0 0 2 2 2 0 YqjK-like protein MbeB_N PF04837.12 EPE28514.1 - 0.12 12.6 3.8 1.7 9.0 0.0 3.4 4 0 0 4 4 4 0 MbeB-like, N-term conserved region TBCA PF02970.16 EPE28514.1 - 0.13 12.6 4.1 8.7 6.8 0.1 3.1 2 1 1 3 3 3 0 Tubulin binding cofactor A Exonuc_VII_L PF02601.15 EPE28514.1 - 0.22 11.0 4.8 0.3 10.6 4.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SlyX PF04102.12 EPE28514.1 - 5.4 7.7 10.8 4.9 7.9 0.1 3.5 2 1 2 4 4 4 0 SlyX Methyltransf_23 PF13489.6 EPE28515.1 - 8.8e-24 84.2 0.0 1.4e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE28515.1 - 9.3e-10 39.1 0.0 3.3e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE28515.1 - 2.5e-08 34.6 0.0 1.9e-07 31.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE28515.1 - 1.2e-06 28.4 0.0 0.0044 16.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EPE28515.1 - 3.4e-06 27.6 0.0 8.1e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPE28515.1 - 0.00068 19.2 0.0 0.038 13.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EPE28515.1 - 0.0065 16.0 0.0 0.064 12.7 0.0 2.5 4 0 0 4 4 4 1 Putative methyltransferase FtsJ PF01728.19 EPE28515.1 - 0.012 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 EPE28515.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EPE28515.1 - 0.023 14.0 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EPE28515.1 - 0.051 12.9 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain Transposase_28 PF04195.12 EPE28515.1 - 0.067 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative gypsy type transposon Methyltransf_16 PF10294.9 EPE28515.1 - 0.097 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DUF2407_C PF13373.6 EPE28516.1 - 2.4e-39 134.7 0.2 3.5e-39 134.2 0.2 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EPE28516.1 - 1.7e-28 99.3 0.0 2.5e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Aminotran_1_2 PF00155.21 EPE28517.1 - 9.6e-60 202.7 0.0 2.6e-59 201.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EPE28517.1 - 0.054 12.0 0.0 0.08 11.5 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Rhodanese_C PF12368.8 EPE28518.1 - 8.5e-13 48.5 7.9 1.9e-12 47.4 7.9 1.6 1 0 0 1 1 1 1 Rhodanase C-terminal UPF0176_N PF17773.1 EPE28518.1 - 3.6e-09 36.8 0.0 1.3e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 UPF0176 acylphosphatase like domain Fungal_trans PF04082.18 EPE28519.1 - 3.5e-06 26.3 0.0 6.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Utp12 PF04003.12 EPE28521.1 - 3.8e-25 88.3 0.2 5.5e-25 87.8 0.2 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Bromodomain PF00439.25 EPE28522.1 - 1.1e-35 121.5 0.4 8.4e-19 67.4 0.1 2.4 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 EPE28522.1 - 1.2e-10 41.4 0.1 4e-10 39.7 0.1 2.0 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation HAD_2 PF13419.6 EPE28523.1 - 3.2e-18 66.5 0.0 4.4e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPE28523.1 - 3.1e-12 47.2 0.0 3.4e-10 40.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPE28523.1 - 0.00034 20.6 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EPE28523.1 - 0.00064 19.8 0.0 0.028 14.5 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EPE28523.1 - 0.19 12.1 0.0 1.1 9.6 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Dabb PF07876.12 EPE28524.1 - 3e-23 82.3 0.0 3.3e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fe-S_biosyn PF01521.20 EPE28525.1 - 2.9e-19 69.3 0.0 4.1e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF1741 PF08427.10 EPE28526.1 - 3.3e-89 298.6 0.4 6.7e-89 297.5 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Baculo_PEP_C PF04513.12 EPE28527.1 - 0.18 11.8 1.6 18 5.3 0.7 3.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus adh_short PF00106.25 EPE28528.1 - 2e-23 82.9 0.2 6.2e-20 71.5 0.3 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE28528.1 - 1e-14 54.7 0.4 5.9e-13 48.9 0.4 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE28528.1 - 8.9e-06 25.7 0.1 1.9e-05 24.6 0.1 1.5 1 1 0 1 1 1 1 KR domain NUC173 PF08161.12 EPE28529.1 - 1e-79 267.0 0.1 5.1e-75 251.6 0.0 3.6 3 0 0 3 3 3 2 NUC173 domain HEAT_2 PF13646.6 EPE28529.1 - 0.01 16.2 1.4 0.31 11.4 0.1 3.6 3 0 0 3 3 3 0 HEAT repeats Vac14_Fab1_bd PF12755.7 EPE28529.1 - 0.019 15.6 0.0 1.5e+02 3.1 0.0 4.6 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EPE28529.1 - 0.039 14.2 0.4 23 5.6 0.1 3.8 4 0 0 4 4 4 0 HEAT repeat Ipi1_N PF12333.8 EPE28529.1 - 0.052 14.1 2.3 45 4.7 0.0 4.7 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation TFCD_C PF12612.8 EPE28529.1 - 0.099 12.5 5.8 14 5.4 0.1 4.6 4 1 0 4 4 4 0 Tubulin folding cofactor D C terminal DUF4646 PF15496.6 EPE28530.1 - 2.3e-07 31.4 0.0 4.8e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) DUF1542 PF07564.11 EPE28530.1 - 0.37 10.9 1.7 0.68 10.1 1.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) HAUS4 PF14735.6 EPE28531.1 - 3.5e-06 26.9 4.5 6.4e-06 26.0 4.5 1.4 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 YgaB PF14182.6 EPE28531.1 - 0.081 13.3 0.8 0.4 11.1 0.0 2.3 2 0 0 2 2 2 0 YgaB-like protein Aminotran_1_2 PF00155.21 EPE28532.1 - 9.7e-90 301.3 0.0 1.1e-89 301.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CPT PF07931.12 EPE28533.1 - 0.00027 20.8 0.0 0.0006 19.7 0.0 1.7 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 EPE28533.1 - 0.0058 17.2 0.0 0.024 15.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EPE28533.1 - 0.0085 16.4 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 EPE28533.1 - 0.018 14.8 0.0 0.044 13.5 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 EPE28533.1 - 0.092 12.5 0.0 15 5.3 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA_33 PF13671.6 EPE28533.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain zinc-ribbons_6 PF07191.12 EPE28534.1 - 0.02 14.9 6.6 1.4 8.9 3.4 2.9 2 1 1 3 3 3 0 zinc-ribbons zinc_ribbon_15 PF17032.5 EPE28534.1 - 0.072 13.8 3.4 1.1 10.1 1.8 2.8 2 1 0 2 2 2 0 zinc-ribbon family C1_1 PF00130.22 EPE28534.1 - 1.8 8.5 9.2 79 3.3 5.5 3.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 EPE28534.1 - 3.8 7.2 7.8 0.54 9.9 0.2 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 EPE28534.1 - 4.6 7.4 8.7 5 7.2 5.9 2.5 1 1 1 2 2 2 0 Double zinc ribbon DUF917 PF06032.12 EPE28536.1 - 1.2e-126 422.3 0.8 2.2e-126 421.4 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 EPE28536.1 - 1.6e-32 112.6 0.2 7.4e-30 104.0 0.0 2.8 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 EPE28536.1 - 5e-29 101.5 8.6 2.6e-27 95.9 0.3 3.6 3 1 1 4 4 4 2 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 EPE28536.1 - 3.3e-05 23.5 5.1 0.011 15.3 0.1 3.2 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.6 EPE28536.1 - 0.00039 19.1 2.6 0.0039 15.9 0.1 2.9 3 0 0 3 3 3 1 MutL protein StbA PF06406.11 EPE28536.1 - 0.0054 16.0 0.2 1.4 8.1 0.0 2.8 2 1 0 2 2 2 2 StbA protein adh_short PF00106.25 EPE28537.1 - 7.8e-23 80.9 0.0 1e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE28537.1 - 2.2e-13 50.3 0.1 2.7e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE28537.1 - 7.2e-05 22.8 0.0 0.0001 22.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE28537.1 - 0.00018 21.1 0.0 0.0045 16.5 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPE28537.1 - 0.014 15.0 0.5 0.026 14.1 0.2 1.6 2 0 0 2 2 2 0 NmrA-like family GDP_Man_Dehyd PF16363.5 EPE28537.1 - 0.084 12.3 0.0 6.8 6.0 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Diphthamide_syn PF01866.17 EPE28538.1 - 7.1e-118 393.5 0.0 9.6e-118 393.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Lactamase_B PF00753.27 EPE28539.1 - 2.7e-05 24.3 0.0 0.00065 19.8 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EPE28539.1 - 0.0016 18.0 0.0 0.0059 16.1 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain adh_short_C2 PF13561.6 EPE28540.1 - 9.8e-43 146.4 0.7 1.2e-42 146.0 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE28540.1 - 1.3e-39 135.7 0.1 1.8e-39 135.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE28540.1 - 2.4e-09 37.3 0.4 3.7e-09 36.7 0.4 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EPE28540.1 - 0.014 14.8 0.0 0.55 9.6 0.0 2.5 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EPE28540.1 - 0.02 14.3 0.1 0.14 11.6 0.1 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ICL PF00463.21 EPE28541.1 - 9.8e-293 971.4 0.2 1.1e-292 971.2 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EPE28541.1 - 3.8e-11 42.9 0.1 2.2e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Trehalase PF01204.18 EPE28542.1 - 9.5e-190 631.8 0.1 1.1e-189 631.5 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EPE28542.1 - 1.1e-16 60.2 0.1 1.8e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Glyco_trans_2_3 PF13632.6 EPE28543.1 - 7.6e-52 176.1 1.3 7.6e-52 176.1 1.3 1.9 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EPE28543.1 - 2.4e-05 24.2 0.0 6.6e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EPE28543.1 - 0.00044 19.8 0.0 0.00087 18.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 gag-asp_proteas PF13975.6 EPE28544.1 - 0.029 14.9 0.0 0.069 13.7 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease MciZ PF13072.6 EPE28545.1 - 0.03 14.1 0.2 0.066 13.0 0.2 1.5 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ Asp_protease_2 PF13650.6 EPE28548.1 - 0.0093 16.6 0.1 0.039 14.6 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EPE28548.1 - 0.056 14.0 0.0 0.22 12.1 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Sugar_tr PF00083.24 EPE28550.1 - 7.2e-81 272.3 13.8 8.4e-81 272.1 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE28550.1 - 3.9e-21 75.4 32.5 9.3e-18 64.3 4.4 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Acetyltransf_10 PF13673.7 EPE28552.1 - 7.1e-08 32.4 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE28552.1 - 9.4e-08 32.3 0.0 1.3e-07 31.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE28552.1 - 3.1e-07 30.7 0.0 4.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 EPE28552.1 - 0.018 14.7 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family FR47 PF08445.10 EPE28552.1 - 0.022 14.7 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 EPE28552.1 - 0.077 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans_2 PF11951.8 EPE28553.1 - 2.5e-34 118.7 4.3 7.9e-33 113.8 4.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE28553.1 - 1.2e-09 38.2 10.0 1.9e-09 37.5 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAP PF02037.27 EPE28554.1 - 2.3e-17 62.3 8.2 5.2e-08 32.5 0.1 4.2 3 1 0 3 3 3 2 SAP domain Telomere_Sde2_2 PF13297.6 EPE28554.1 - 1.6e-05 24.5 2.1 0.0025 17.4 0.1 3.6 3 0 0 3 3 3 1 Telomere stability C-terminal BBE PF08031.12 EPE28554.1 - 0.11 12.6 0.0 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 Berberine and berberine like COMMD1_N PF17221.3 EPE28554.1 - 0.4 11.0 8.0 0.25 11.7 1.1 2.8 2 1 0 3 3 3 0 COMMD1 N-terminal domain HeH PF12949.7 EPE28554.1 - 0.8 9.5 4.0 73 3.2 0.0 4.1 3 1 0 3 3 3 0 HeH/LEM domain Pox_E6 PF04656.12 EPE28555.1 - 0.088 11.2 0.1 0.1 11.0 0.1 1.1 1 0 0 1 1 1 0 Pox virus E6 protein RRM_1 PF00076.22 EPE28557.1 - 1.2e-20 73.1 0.1 7.6e-10 38.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPE28557.1 - 0.0016 18.5 0.0 0.14 12.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Ino80_Iec3 PF14612.6 EPE28558.1 - 6.8e-67 226.6 0.3 1.5e-66 225.5 0.3 1.5 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Iso_dh PF00180.20 EPE28559.1 - 4.8e-71 239.7 0.0 5.6e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Not3 PF04065.15 EPE28562.1 - 2.4e-90 302.0 26.0 2.4e-90 302.0 26.0 1.6 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EPE28562.1 - 7e-42 142.6 12.8 2.8e-41 140.7 12.8 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 EPE28562.1 - 0.0054 17.1 3.4 0.0054 17.1 3.4 2.8 4 0 0 4 4 4 1 Syntaxin-like protein DUF2373 PF10180.9 EPE28562.1 - 0.017 15.0 3.1 0.043 13.7 3.1 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.13 EPE28562.1 - 0.61 10.6 11.5 0.4 11.2 2.0 3.1 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 HrpB2 PF09487.10 EPE28562.1 - 1.2 9.6 7.3 2.9 8.3 0.3 3.1 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB2) 4HB_MCP_1 PF12729.7 EPE28562.1 - 5.2 6.6 17.5 0.64 9.5 7.4 2.4 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Snapin_Pallidin PF14712.6 EPE28562.1 - 6.4 7.3 15.0 0.86 10.1 0.5 3.6 4 0 0 4 4 4 0 Snapin/Pallidin DUF1192 PF06698.11 EPE28562.1 - 8.1 6.6 7.9 1.2 9.3 1.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Tyr_Deacylase PF02580.16 EPE28563.1 - 6.9e-52 175.8 0.2 7.7e-52 175.7 0.2 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Pro_isomerase PF00160.21 EPE28564.1 - 9e-49 165.8 0.2 1.4e-48 165.2 0.2 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EPE28564.1 - 0.014 15.4 2.6 0.2 11.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EPE28564.1 - 0.037 14.2 0.2 0.072 13.3 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPE28564.1 - 0.1 12.9 1.8 0.15 12.4 0.3 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EPE28564.1 - 0.13 12.6 0.1 3.3 8.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RasGAP PF00616.19 EPE28565.1 - 3e-29 102.2 0.0 8.2e-22 77.9 0.0 2.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EPE28565.1 - 1e-06 29.0 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain MRP-L20 PF12824.7 EPE28567.1 - 4.5e-47 160.3 5.2 5.4e-47 160.0 5.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_38 PF13936.6 EPE28567.1 - 0.0022 17.7 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain N_BRCA1_IG PF16158.5 EPE28568.1 - 4.1e-33 114.2 0.1 1.9e-32 112.0 0.0 2.3 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 EPE28568.1 - 5.1e-21 74.2 49.0 4.7e-06 26.3 6.7 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 EPE28568.1 - 2.7e-05 24.4 38.8 0.13 12.6 7.9 4.6 4 0 0 4 4 4 4 C1 domain Btz PF09405.10 EPE28569.1 - 1.7e-26 93.0 3.3 5.2e-26 91.4 3.3 1.8 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Aft1_HRA PF11786.8 EPE28570.1 - 1.1e-22 80.1 5.5 1.1e-22 80.1 5.5 3.0 2 1 1 3 3 3 1 Aft1 HRA domain Aft1_HRR PF11787.8 EPE28570.1 - 1.2e-22 80.9 0.9 1.2e-22 80.9 0.9 3.8 3 2 0 3 3 3 1 Aft1 HRR domain bZIP_1 PF00170.21 EPE28570.1 - 8.1e-14 51.5 5.2 1.4e-13 50.7 5.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.8 EPE28570.1 - 9.9e-11 41.9 6.3 9.9e-11 41.9 6.3 3.8 4 0 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.15 EPE28570.1 - 1.5e-06 28.1 6.4 2.8e-06 27.3 6.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EPE28570.1 - 0.00039 20.9 3.7 0.0011 19.5 3.7 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor YabA PF06156.13 EPE28570.1 - 0.054 14.1 0.2 0.15 12.7 0.2 1.7 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 EPE28570.1 - 0.45 10.3 2.0 1.1 9.1 2.0 1.6 1 0 0 1 1 1 0 Septum formation initiator Macoilin PF09726.9 EPE28570.1 - 5.6 5.4 11.8 7.4 5.0 11.8 1.1 1 0 0 1 1 1 0 Macoilin family GST_N_3 PF13417.6 EPE28571.1 - 3.5e-09 36.9 0.1 6.9e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EPE28571.1 - 0.00026 21.1 0.0 0.00045 20.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EPE28571.1 - 0.00032 21.0 0.0 0.00068 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPE28571.1 - 0.078 13.0 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SspH PF08141.12 EPE28571.1 - 0.18 12.0 0.1 13 6.0 0.0 2.4 2 0 0 2 2 2 0 Small acid-soluble spore protein H family NACHT PF05729.12 EPE28572.1 - 1.3e-08 34.9 0.1 0.00013 22.0 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 EPE28572.1 - 6.6e-07 29.9 0.1 3.5e-06 27.5 0.0 2.3 3 0 0 3 3 2 1 AAA ATPase domain NB-ARC PF00931.22 EPE28572.1 - 0.00055 19.2 0.1 0.0017 17.6 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.27 EPE28572.1 - 0.00081 19.9 0.0 0.003 18.1 0.0 2.0 1 0 0 1 1 1 1 ABC transporter DUF900 PF05990.12 EPE28572.1 - 0.0011 18.5 0.0 0.022 14.3 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) ATPase_2 PF01637.18 EPE28572.1 - 0.0014 18.6 0.0 0.0075 16.2 0.0 2.3 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea Abhydrolase_6 PF12697.7 EPE28572.1 - 0.0057 17.3 0.0 0.012 16.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE28572.1 - 0.012 14.8 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AAA_22 PF13401.6 EPE28572.1 - 0.017 15.4 0.0 0.18 12.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain PGAP1 PF07819.13 EPE28572.1 - 0.021 14.5 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein AAA_29 PF13555.6 EPE28572.1 - 0.032 14.0 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EPE28572.1 - 0.034 14.3 0.0 0.078 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EPE28572.1 - 0.043 13.5 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF676 PF05057.14 EPE28572.1 - 0.057 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RNA_helicase PF00910.22 EPE28572.1 - 0.062 13.7 1.0 0.23 11.9 0.1 2.4 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 EPE28572.1 - 0.13 12.0 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EPE28572.1 - 0.16 11.7 0.0 0.47 10.2 0.0 1.8 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 EPE28572.1 - 0.16 12.0 0.0 0.57 10.3 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase TFIIA_gamma_C PF02751.14 EPE28572.1 - 0.26 11.5 1.4 11 6.3 0.2 2.6 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit DWNN PF08783.11 EPE28573.1 - 4.4e-31 107.0 0.0 9.4e-31 105.9 0.0 1.6 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EPE28573.1 - 1.9e-08 33.9 4.0 3.4e-08 33.2 4.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EPE28573.1 - 0.00073 19.5 1.0 0.0013 18.7 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.15 EPE28573.1 - 0.0062 16.7 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 U-box domain DUF3332 PF11810.8 EPE28573.1 - 0.034 13.8 0.6 0.072 12.7 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) zf-RING_6 PF14835.6 EPE28573.1 - 0.044 13.7 2.2 0.081 12.8 2.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 EPE28573.1 - 0.14 12.5 6.6 0.33 11.3 6.6 1.6 1 0 0 1 1 1 0 Ring finger domain GRP PF07172.11 EPE28573.1 - 0.23 12.2 19.0 0.13 13.0 16.3 1.9 2 0 0 2 2 1 0 Glycine rich protein family zf-RING_4 PF14570.6 EPE28573.1 - 0.35 10.7 5.9 0.78 9.6 5.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 EPE28573.1 - 0.58 10.0 4.4 1.3 8.9 4.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EPE28573.1 - 1.3 9.2 6.6 2.5 8.2 6.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EPE28573.1 - 1.6 8.7 9.4 3.3 7.6 9.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPE28573.1 - 1.6 8.9 8.6 5 7.4 8.6 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EPE28573.1 - 2.2 8.2 15.4 0.026 14.3 8.1 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TMEM213 PF15192.6 EPE28576.1 - 0.079 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 TMEM213 family Yippee-Mis18 PF03226.14 EPE28578.1 - 5.4e-18 65.1 0.0 8.2e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Aim19 PF10315.9 EPE28578.1 - 0.031 14.6 0.0 0.059 13.7 0.0 1.4 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 19 PIF1 PF05970.14 EPE28579.1 - 1.4e-40 139.6 1.6 8.9e-28 97.5 0.0 3.7 2 1 1 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 EPE28579.1 - 3.9e-20 72.4 0.0 7.8e-17 61.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EPE28579.1 - 3.2e-14 53.5 0.0 6e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cauli_VI PF01693.16 EPE28579.1 - 1.1e-13 51.2 1.9 3.5e-13 49.6 1.9 1.9 1 0 0 1 1 1 1 Caulimovirus viroplasmin AAA_22 PF13401.6 EPE28579.1 - 8.5e-05 22.9 0.0 0.00021 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EPE28579.1 - 8.6e-05 22.6 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EPE28579.1 - 0.00053 19.8 0.3 0.04 13.7 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SSE PF00437.20 EPE28579.1 - 0.00084 18.5 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 EPE28579.1 - 0.0031 16.5 0.0 0.018 14.0 0.0 1.9 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 EPE28579.1 - 0.0032 17.9 0.0 0.0081 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EPE28579.1 - 0.0045 16.5 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 EPE28579.1 - 0.0054 16.6 0.2 2.6 7.8 0.0 2.6 1 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EPE28579.1 - 0.016 15.2 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.18 EPE28579.1 - 0.022 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pox_A32 PF04665.12 EPE28579.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein Mg_chelatase PF01078.21 EPE28579.1 - 0.026 13.9 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF853 PF05872.12 EPE28579.1 - 0.027 13.1 0.0 0.043 12.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_5 PF07728.14 EPE28579.1 - 0.033 14.2 0.0 8.7 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EPE28579.1 - 0.036 14.5 0.0 2.8 8.4 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EPE28579.1 - 0.056 12.7 0.0 0.37 10.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SH3_13 PF18335.1 EPE28579.1 - 0.058 13.2 0.6 0.36 10.7 0.0 2.6 3 0 0 3 3 3 0 ATP-dependent RecD-like DNA helicase SH3 domain UvrD_C_2 PF13538.6 EPE28579.1 - 0.072 12.9 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EPE28579.1 - 0.072 11.0 0.1 0.74 7.7 0.0 2.0 2 0 0 2 2 2 0 Helicase NB-ARC PF00931.22 EPE28579.1 - 0.077 12.2 0.0 0.31 10.2 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EPE28579.1 - 0.081 12.8 0.0 0.45 10.4 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea UvrD-helicase PF00580.21 EPE28579.1 - 0.12 11.9 0.9 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain NTPase_1 PF03266.15 EPE28579.1 - 0.2 11.5 0.5 0.62 10.0 0.0 2.1 3 0 0 3 3 2 0 NTPase ODC_AZ PF02100.17 EPE28580.1 - 1.2e-41 141.3 0.2 1.6e-41 140.8 0.2 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Paralemmin PF03285.15 EPE28581.1 - 0.38 10.3 10.6 1.6 8.3 0.0 2.7 2 2 0 2 2 2 0 Paralemmin AA_permease PF00324.21 EPE28583.1 - 4.2e-116 388.4 42.2 5e-116 388.1 42.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE28583.1 - 7.1e-27 94.3 41.9 8.7e-27 94.0 41.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF218 PF02698.17 EPE28584.1 - 1.3e-05 25.2 0.0 1.6e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain Plus-3 PF03126.18 EPE28586.1 - 3.5e-31 107.9 0.1 9.4e-31 106.6 0.0 1.8 2 0 0 2 2 2 1 Plus-3 domain CsgG PF03783.14 EPE28586.1 - 0.078 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG CTP_transf_like PF01467.26 EPE28586.1 - 0.095 12.9 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Cytidylyltransferase-like COQ7 PF03232.13 EPE28587.1 - 3.1e-70 235.4 0.3 4.9e-70 234.8 0.3 1.3 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 UPF0184 PF03670.13 EPE28587.1 - 0.0025 18.2 0.2 0.0039 17.5 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0184) Rubrerythrin PF02915.17 EPE28587.1 - 0.0032 17.9 0.0 0.0065 16.9 0.0 1.7 1 1 0 1 1 1 1 Rubrerythrin GAT PF03127.14 EPE28587.1 - 0.08 13.3 0.2 0.13 12.6 0.2 1.4 1 0 0 1 1 1 0 GAT domain DUF4777 PF16007.5 EPE28587.1 - 0.19 12.0 0.1 0.38 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) PLDc PF00614.22 EPE28588.1 - 2e-15 56.3 0.5 2.9e-07 30.4 0.1 2.9 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EPE28588.1 - 2.9e-13 49.9 0.0 4.9e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.24 EPE28588.1 - 3.2e-07 30.3 0.0 2.4e-06 27.5 0.0 2.5 2 1 0 2 2 2 1 PX domain PH PF00169.29 EPE28588.1 - 0.11 13.1 0.2 0.36 11.4 0.2 1.9 1 0 0 1 1 1 0 PH domain Kri1 PF05178.12 EPE28588.1 - 1.1 9.8 4.9 1.2 9.7 1.1 2.5 2 0 0 2 2 2 0 KRI1-like family zf_CCCH_4 PF18345.1 EPE28590.1 - 1.2e-05 25.2 4.9 2.1e-05 24.4 4.9 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EPE28590.1 - 1.3e-05 24.9 3.3 2.1e-05 24.2 3.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EPE28590.1 - 0.00067 19.5 4.8 0.0011 18.9 4.8 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EPE28590.1 - 0.0016 19.1 0.6 0.0016 19.1 0.6 2.1 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 EPE28590.1 - 0.27 11.8 2.6 0.46 11.0 2.6 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger ACC_epsilon PF13822.6 EPE28590.1 - 9.8 7.0 9.2 12 6.7 0.3 3.6 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Sec1 PF00995.23 EPE28591.1 - 1.5e-127 427.2 0.0 1.8e-127 427.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Nuc_deoxyrib_tr PF05014.15 EPE28592.1 - 0.023 14.7 2.3 0.76 9.8 0.3 2.2 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase DUF5585 PF17823.1 EPE28592.1 - 0.65 8.9 26.6 0.75 8.7 26.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) GH131_N PF18271.1 EPE28594.1 - 9.1e-60 202.5 0.8 1.3e-59 202.0 0.8 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 EPE28594.1 - 3.9e-08 33.1 11.6 1e-07 31.7 11.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Trypan_PARP PF05887.11 EPE28594.1 - 0.012 15.6 0.3 0.022 14.8 0.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pro-kuma_activ PF09286.11 EPE28595.1 - 1.2e-38 132.6 0.1 2.8e-38 131.4 0.1 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EPE28595.1 - 2.6e-06 26.9 0.0 1.1e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Subtilase family LMWPc PF01451.21 EPE28596.1 - 9.5e-42 142.7 0.0 1.1e-41 142.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Chitin_synth_1 PF01644.17 EPE28597.1 - 2.5e-76 255.2 0.1 3.8e-76 254.6 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EPE28597.1 - 7.3e-30 102.7 0.0 1.4e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EPE28597.1 - 3.1e-21 75.6 4.7 3.6e-18 65.5 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase ATP_synt_H PF05493.13 EPE28597.1 - 8.8 6.9 12.5 20 5.8 6.3 2.8 2 0 0 2 2 2 0 ATP synthase subunit H G_glu_transpept PF01019.21 EPE28598.1 - 1.1e-142 476.5 0.0 1.2e-142 476.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PCRF PF03462.18 EPE28599.1 - 1.3e-53 181.8 0.2 1.3e-53 181.8 0.2 2.1 3 0 0 3 3 3 1 PCRF domain RF-1 PF00472.20 EPE28599.1 - 2.9e-33 114.2 7.4 5.3e-33 113.4 2.9 2.3 2 0 0 2 2 2 1 RF-1 domain MIR PF02815.19 EPE28599.1 - 0.058 13.2 0.1 0.093 12.6 0.1 1.3 1 0 0 1 1 1 0 MIR domain DUF3328 PF11807.8 EPE28600.1 - 1.1e-24 87.4 0.0 1.5e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_S10 PF00450.22 EPE28601.1 - 6.3e-85 286.1 0.0 8.7e-85 285.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Aminotran_4 PF01063.19 EPE28602.1 - 2.3e-24 86.5 0.0 3.2e-23 82.8 0.0 2.0 1 1 0 1 1 1 1 Amino-transferase class IV TPR_1 PF00515.28 EPE28603.1 - 3.3e-45 150.1 29.5 6.5e-06 25.7 0.0 11.5 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 EPE28603.1 - 5.1e-44 144.9 27.2 0.00015 21.6 0.0 11.5 10 1 1 11 11 11 10 Tetratricopeptide repeat TPR_16 PF13432.6 EPE28603.1 - 2.2e-25 89.0 6.3 7.3e-07 29.7 0.0 7.1 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EPE28603.1 - 4.7e-23 80.6 24.8 5.4e-05 22.8 0.1 8.9 5 2 3 8 8 8 7 TPR repeat TPR_8 PF13181.6 EPE28603.1 - 4.1e-22 76.5 27.9 0.0028 17.7 0.1 11.3 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.6 EPE28603.1 - 8.5e-22 77.2 27.9 0.00088 19.5 2.5 9.0 5 3 4 9 9 9 8 Tetratricopeptide repeat TPR_17 PF13431.6 EPE28603.1 - 3.5e-21 74.0 7.7 0.00052 20.2 0.0 9.2 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 EPE28603.1 - 7.9e-14 51.9 18.6 1.8e-05 25.1 0.5 7.0 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EPE28603.1 - 2.4e-13 49.1 20.6 0.03 14.3 0.1 9.4 8 1 1 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE28603.1 - 4e-12 46.2 15.4 0.036 14.3 0.3 5.4 3 1 2 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EPE28603.1 - 4.4e-12 46.0 11.6 6.7e-06 26.2 0.0 6.3 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EPE28603.1 - 5.3e-11 42.4 18.3 0.063 14.1 0.2 9.5 4 3 7 11 11 11 4 Tetratricopeptide repeat TPR_10 PF13374.6 EPE28603.1 - 2.1e-09 36.9 23.5 0.056 13.3 0.2 9.4 10 0 0 10 10 9 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 EPE28603.1 - 8.8e-07 28.3 13.2 0.14 11.7 0.0 7.0 7 0 0 7 7 7 2 SHNi-TPR TPR_MalT PF17874.1 EPE28603.1 - 2e-06 27.4 3.8 2.3e-05 24.0 1.1 2.6 2 0 0 2 2 2 1 MalT-like TPR region DUF3856 PF12968.7 EPE28603.1 - 0.00025 21.1 5.3 9.2 6.3 0.0 5.9 5 2 0 5 5 5 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 EPE28603.1 - 0.00061 20.2 0.3 53 4.9 0.1 6.0 7 0 0 7 7 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPE28603.1 - 0.0015 19.0 25.0 4.3 8.2 0.0 9.4 11 0 0 11 11 9 1 Tetratricopeptide repeat TAF1_subA PF14929.6 EPE28603.1 - 0.055 12.9 0.2 0.17 11.3 0.1 1.7 1 1 0 1 1 1 0 TAF RNA Polymerase I subunit A MIT PF04212.18 EPE28603.1 - 0.065 13.3 16.6 9.5 6.4 0.0 6.9 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain HrpB1_HrpK PF09613.10 EPE28603.1 - 0.066 12.9 1.0 0.6 9.7 0.3 2.7 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) MAS20 PF02064.15 EPE28603.1 - 0.19 11.8 9.0 18 5.4 0.0 4.8 4 1 1 5 5 5 0 MAS20 protein import receptor ANAPC5 PF12862.7 EPE28603.1 - 0.41 10.7 7.2 7.8 6.6 0.3 4.1 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 5 Sel1 PF08238.12 EPE28603.1 - 1.3 9.8 7.5 19 6.1 0.0 5.0 5 0 0 5 5 4 0 Sel1 repeat TPR_3 PF07720.12 EPE28603.1 - 5.8 7.0 16.8 23 5.1 0.7 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF3455 PF11937.8 EPE28605.1 - 2.8e-38 131.8 0.1 4.2e-38 131.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) WASH_WAHD PF11945.8 EPE28605.1 - 0.07 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 WAHD domain of WASH complex HET PF06985.11 EPE28606.1 - 8.2e-38 130.0 0.9 1.8e-37 129.0 0.9 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 EPE28608.1 - 5.8e-68 229.1 0.0 6.9e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE28608.1 - 2.6e-31 108.8 0.0 4.5e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EPE28608.1 - 0.011 14.7 0.0 0.023 13.7 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EPE28608.1 - 0.064 13.2 0.1 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family IRK PF01007.20 EPE28608.1 - 0.093 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Kdo PF06293.14 EPE28608.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_106 PF17132.4 EPE28610.1 - 1.8e-40 139.0 0.4 3.8e-35 121.4 0.0 2.1 1 1 0 2 2 2 2 alpha-L-rhamnosidase EHN PF06441.12 EPE28611.1 - 3.1e-30 104.7 0.1 6e-30 103.8 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EPE28611.1 - 1.5e-16 60.9 0.3 2.7e-16 60.0 0.3 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE28611.1 - 6.5e-05 23.6 0.4 0.0001 23.0 0.2 1.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family FYVE PF01363.21 EPE28612.1 - 0.0027 17.8 6.9 0.0027 17.8 6.9 2.4 3 0 0 3 3 3 1 FYVE zinc finger PHD_3 PF13922.6 EPE28612.1 - 0.11 12.8 0.3 0.11 12.8 0.3 2.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx FYVE_2 PF02318.16 EPE28612.1 - 1.7 8.9 8.0 4.4 7.6 1.7 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger DUF543 PF04418.12 EPE28613.1 - 0.0064 16.4 1.8 0.5 10.4 0.3 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF543) Mid2 PF04478.12 EPE28613.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MFS_MOT1 PF16983.5 EPE28614.1 - 5.4e-64 213.5 27.5 1.8e-35 121.7 8.0 2.5 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 EPE28614.1 - 1.2e-06 27.6 8.3 0.00014 20.8 0.3 2.5 2 1 0 2 2 2 2 Sulfate permease family Xan_ur_permease PF00860.20 EPE28614.1 - 1.3e-05 24.1 23.3 0.0018 17.0 16.2 2.3 1 1 1 2 2 2 2 Permease family BenE PF03594.13 EPE28614.1 - 0.033 13.0 14.5 0.83 8.4 14.5 2.7 1 1 0 1 1 1 0 Benzoate membrane transport protein MRC1 PF09444.10 EPE28615.1 - 4.4e-43 147.3 19.8 4.4e-43 147.3 19.8 8.3 9 1 0 10 10 10 1 MRC1-like domain Ribosomal_L22 PF00237.19 EPE28616.1 - 9.9e-29 99.6 0.3 2e-28 98.6 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e FAM25 PF15825.5 EPE28616.1 - 0.017 15.5 3.0 0.037 14.4 3.0 1.6 1 0 0 1 1 1 0 FAM25 family LEA_2 PF03168.13 EPE28616.1 - 0.083 13.4 0.1 0.21 12.2 0.1 1.7 1 0 0 1 1 1 0 Late embryogenesis abundant protein RRM_1 PF00076.22 EPE28617.1 - 2.9e-41 139.2 0.1 1.5e-14 53.5 0.1 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPE28617.1 - 5.4e-34 115.9 0.0 4.6e-29 100.1 0.0 3.6 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EPE28617.1 - 1.1e-07 31.8 0.0 0.034 14.2 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 EPE28617.1 - 0.017 14.9 0.2 2.7 7.7 0.0 3.5 4 0 0 4 4 4 0 Rrp7 RRM-like N-terminal domain RRM_5 PF13893.6 EPE28617.1 - 0.029 13.9 0.0 2.1 7.9 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EPE28617.1 - 0.1 12.7 0.1 1.6 8.8 0.1 2.8 2 0 0 2 2 2 0 RNA binding motif RRM_7 PF16367.5 EPE28617.1 - 0.2 11.8 0.3 51 4.1 0.0 3.7 4 0 0 4 4 4 0 RNA recognition motif BTB PF00651.31 EPE28619.1 - 0.011 16.0 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain DUF3087 PF11286.8 EPE28620.1 - 0.36 10.3 0.9 0.76 9.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) adh_short_C2 PF13561.6 EPE28621.1 - 4.1e-60 203.2 1.5 4.9e-60 203.0 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE28621.1 - 3.8e-45 153.8 0.8 4.7e-45 153.5 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_25 PF13649.6 EPE28621.1 - 0.0004 21.0 0.1 0.00078 20.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE28621.1 - 0.0029 18.2 0.1 0.0055 17.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain KR PF08659.10 EPE28621.1 - 0.0063 16.4 0.1 0.0091 15.9 0.1 1.2 1 0 0 1 1 1 1 KR domain ATP-synt_C PF00137.21 EPE28621.1 - 0.27 11.6 4.7 0.61 10.5 4.7 1.6 1 0 0 1 1 1 0 ATP synthase subunit C Glyoxalase PF00903.25 EPE28622.1 - 2.2e-08 34.4 0.0 8.2e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EPE28622.1 - 1.1e-07 31.7 0.0 1.6e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EPE28622.1 - 0.00014 22.6 0.0 0.00016 22.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Tudor_4 PF18358.1 EPE28622.1 - 0.013 15.1 0.2 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain Glyoxalase_3 PF13468.6 EPE28622.1 - 0.022 14.8 0.0 0.024 14.8 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain UTP15_C PF09384.10 EPE28623.1 - 3.2e-51 172.9 0.0 4.9e-51 172.3 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EPE28623.1 - 1.5e-21 76.2 1.0 1.2e-05 25.9 0.0 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE28623.1 - 1.1e-08 35.3 0.2 0.0078 16.5 0.0 4.3 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain ATP-synt_E PF05680.12 EPE28623.1 - 0.029 14.7 0.1 0.057 13.8 0.1 1.4 1 0 0 1 1 1 0 ATP synthase E chain RAB3GAP2_N PF14655.6 EPE28623.1 - 0.065 12.5 0.1 5.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus bZIP_1 PF00170.21 EPE28624.1 - 0.0014 18.7 1.4 0.003 17.6 1.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor AT_hook PF02178.19 EPE28624.1 - 0.026 14.4 0.7 0.061 13.2 0.7 1.7 1 0 0 1 1 1 0 AT hook motif YlzJ PF14035.6 EPE28626.1 - 0.16 12.2 0.0 0.49 10.6 0.0 1.8 1 0 0 1 1 1 0 YlzJ-like protein Cript PF10235.9 EPE28627.1 - 1.9e-24 86.0 9.2 1.9e-24 86.0 9.2 1.4 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 EPE28627.1 - 0.0074 16.3 13.0 0.011 15.8 8.6 2.3 2 0 0 2 2 2 1 Double zinc ribbon zinc-ribbons_6 PF07191.12 EPE28627.1 - 0.0075 16.2 6.5 0.0095 15.9 2.9 2.0 2 0 0 2 2 2 1 zinc-ribbons zinc_ribbon_15 PF17032.5 EPE28627.1 - 0.041 14.6 12.8 0.067 14.0 8.9 2.7 2 1 0 2 2 2 0 zinc-ribbon family zinc_ribbon_2 PF13240.6 EPE28627.1 - 0.055 13.2 1.9 0.055 13.2 1.9 3.2 2 1 2 4 4 4 0 zinc-ribbon domain Roc PF08477.13 EPE28627.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase zf-C3HC4_3 PF13920.6 EPE28627.1 - 6.1 6.8 13.7 4.3 7.3 3.8 3.0 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 EPE28627.1 - 6.6 6.3 12.2 15 5.2 0.7 3.3 2 1 1 3 3 3 0 zinc-ribbon domain PhoLip_ATPase_C PF16212.5 EPE28628.1 - 1.5e-82 277.1 18.5 1.5e-82 277.1 18.5 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EPE28628.1 - 6e-27 93.1 7.1 1.6e-26 91.7 7.1 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EPE28628.1 - 3.9e-11 42.9 0.1 1.6e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EPE28628.1 - 6.6e-11 42.9 1.7 4.2e-07 30.5 0.3 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EPE28628.1 - 3.6e-07 29.9 0.0 9.3e-07 28.5 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EPE28628.1 - 0.0012 18.6 0.0 0.014 15.1 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Homeobox_KN PF05920.11 EPE28630.1 - 1.4e-18 66.5 0.6 1.4e-18 66.5 0.6 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EPE28630.1 - 4.3e-08 32.9 1.3 1.3e-07 31.3 1.3 1.9 1 0 0 1 1 1 1 Homeodomain PI3K_1B_p101 PF10486.9 EPE28631.1 - 0.14 9.9 0.0 0.14 9.9 0.0 2.6 3 0 0 3 3 3 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Miga PF10265.9 EPE28631.1 - 0.15 11.0 4.7 0.15 11.0 0.3 2.4 2 0 0 2 2 2 0 Mitoguardin DIM PF08194.12 EPE28633.1 - 0.02 15.1 0.8 0.042 14.1 0.8 1.7 1 0 0 1 1 1 0 DIM protein YpzI PF14140.6 EPE28636.1 - 2.7 7.8 8.0 2 8.2 0.1 3.8 4 0 0 4 4 4 0 YpzI-like protein Ish1 PF10281.9 EPE28637.1 - 2.4e-94 309.3 20.5 2.9e-13 49.9 0.0 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 EPE28637.1 - 8.2e-13 47.8 0.0 0.049 13.4 0.0 7.6 7 1 0 7 7 7 2 SAP domain HeH PF12949.7 EPE28637.1 - 2.7e-12 46.2 0.0 0.0027 17.4 0.0 6.7 7 0 0 7 7 7 3 HeH/LEM domain Endonuc-dimeris PF09124.10 EPE28637.1 - 2.6e-07 30.7 0.0 0.29 11.3 0.0 5.5 6 0 0 6 6 6 2 T4 recombination endonuclease VII, dimerisation Slx4 PF09494.10 EPE28637.1 - 6.9e-07 29.1 1.5 4.3 7.4 0.0 6.5 6 1 1 7 7 7 2 Slx4 endonuclease ANAPC2 PF08672.11 EPE28637.1 - 0.00042 20.7 0.1 19 5.8 0.0 5.5 7 0 0 7 7 7 0 Anaphase promoting complex (APC) subunit 2 DUF4518 PF15008.6 EPE28637.1 - 0.0055 15.9 4.2 4.3 6.4 0.2 4.0 3 1 1 4 4 4 2 Domain of unknown function (DUF4518) SAP30_Sin3_bdg PF13867.6 EPE28637.1 - 0.11 12.9 1.1 25 5.3 0.0 4.3 5 0 0 5 5 5 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Apolipoprotein PF01442.18 EPE28637.1 - 0.12 12.3 5.2 0.45 10.4 1.0 3.5 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF445 PF04286.12 EPE28637.1 - 1.2 8.9 3.8 2.8 7.6 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF445) DUF2795 PF11387.8 EPE28637.1 - 1.3 9.3 6.6 36 4.7 0.0 5.0 6 0 0 6 6 5 0 Protein of unknown function (DUF2795) SAM_2 PF07647.17 EPE28637.1 - 2.6 8.2 6.0 16 5.7 0.0 4.7 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) AMP-binding PF00501.28 EPE28638.1 - 1.5e-67 228.1 0.0 2e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EPE28638.1 - 0.089 11.5 0.1 0.23 10.1 0.1 1.6 2 0 0 2 2 2 0 Condensation domain MFS_1 PF07690.16 EPE28639.1 - 3.6e-44 151.1 27.7 6.5e-38 130.6 19.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EPE28639.1 - 5.9e-08 32.4 2.9 5.9e-08 32.4 2.9 3.7 2 2 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 EPE28639.1 - 0.0021 16.7 28.6 0.037 12.6 12.7 2.6 2 2 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.13 EPE28639.1 - 0.11 10.9 23.3 3.1 6.1 3.2 2.7 1 1 1 2 2 2 0 Transmembrane secretion effector OATP PF03137.20 EPE28639.1 - 0.35 9.1 18.0 0.012 13.9 1.8 3.3 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family BT1 PF03092.16 EPE28639.1 - 0.4 8.8 12.0 0.02 13.2 2.6 2.2 1 1 0 2 2 2 0 BT1 family AP_endonuc_2 PF01261.24 EPE28640.1 - 1.5e-25 89.9 0.0 2e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Trypsin PF00089.26 EPE28641.1 - 1.5e-63 214.6 7.5 1.7e-63 214.4 7.5 1.0 1 0 0 1 1 1 1 Trypsin CFEM PF05730.11 EPE28642.1 - 4.9e-09 36.2 11.9 7.6e-09 35.5 11.9 1.3 1 0 0 1 1 1 1 CFEM domain CD34_antigen PF06365.12 EPE28642.1 - 0.00068 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Amnionless PF14828.6 EPE28642.1 - 0.0049 15.8 0.0 0.0049 15.8 0.0 1.9 2 0 0 2 2 1 1 Amnionless Cyd_oper_YbgE PF09600.10 EPE28642.1 - 0.025 14.9 0.3 0.061 13.7 0.3 1.6 1 0 0 1 1 1 0 Cyd operon protein YbgE (Cyd_oper_YbgE) Peptidase_M56 PF05569.11 EPE28642.1 - 0.027 13.7 0.2 0.035 13.3 0.2 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 EphA2_TM PF14575.6 EPE28642.1 - 0.027 15.3 0.1 0.05 14.5 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SIT PF15330.6 EPE28642.1 - 0.031 14.7 0.2 0.066 13.7 0.2 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT LapA_dom PF06305.11 EPE28642.1 - 0.036 13.9 0.2 0.072 12.9 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Prosystemin PF07376.11 EPE28642.1 - 0.14 11.7 0.1 0.18 11.3 0.1 1.1 1 0 0 1 1 1 0 Prosystemin MGC-24 PF05283.11 EPE28642.1 - 0.4 11.1 16.8 0.036 14.5 11.5 2.0 2 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin FSA_C PF10479.9 EPE28642.1 - 0.45 8.6 3.3 0.55 8.3 3.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AMPK1_CBM PF16561.5 EPE28643.1 - 1.6e-08 34.6 0.0 3.2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF4687 PF15747.5 EPE28643.1 - 0.35 11.4 3.0 0.58 10.6 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4687) F-box-like PF12937.7 EPE28644.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 F-box-like Ank_2 PF12796.7 EPE28645.1 - 8.5e-20 71.1 0.1 9e-10 39.0 0.0 2.8 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE28645.1 - 1.5e-12 47.7 0.2 3.7e-06 27.4 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE28645.1 - 2.5e-12 45.8 2.0 0.0003 21.0 0.1 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 EPE28645.1 - 1e-10 41.7 4.5 1.3e-06 28.5 0.4 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EPE28645.1 - 7e-09 35.7 1.9 0.00031 21.0 0.2 3.6 4 0 0 4 4 4 2 Ankyrin repeat CAP59_mtransfer PF11735.8 EPE28646.1 - 8.6e-64 215.5 0.0 1.1e-63 215.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Abhydrolase_6 PF12697.7 EPE28647.1 - 7.6e-11 43.0 0.1 9.6e-11 42.7 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF498 PF04430.14 EPE28647.1 - 0.04 14.0 0.1 39 4.4 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF498/DUF598) tRNA-synt_1b PF00579.25 EPE28648.1 - 2.1e-20 73.2 1.2 1.5e-19 70.4 0.0 2.4 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) PRELI PF04707.14 EPE28649.1 - 7.6e-23 81.1 0.1 2.8e-21 76.0 0.0 2.3 2 0 0 2 2 2 2 PRELI-like family Asp PF00026.23 EPE28650.1 - 5.9e-64 216.5 2.6 7.1e-64 216.2 2.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPE28650.1 - 1.4e-09 38.4 4.2 0.00021 21.6 0.2 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Syntaxin PF00804.25 EPE28651.1 - 0.1 12.2 0.5 0.2 11.3 0.5 1.4 1 0 0 1 1 1 0 Syntaxin Kinesin PF00225.23 EPE28653.1 - 2.9e-107 358.4 5.8 7.6e-107 357.1 5.8 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EPE28653.1 - 8.7e-58 194.5 0.1 2.3e-57 193.1 0.1 1.8 1 0 0 1 1 1 1 Microtubule binding Filament PF00038.21 EPE28653.1 - 0.0024 17.5 32.9 0.0024 17.5 32.9 2.5 2 1 0 2 2 2 1 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 EPE28653.1 - 0.0065 16.7 10.1 0.0065 16.7 10.1 4.1 3 1 2 5 5 5 1 JNK_SAPK-associated protein-1 AAA_16 PF13191.6 EPE28653.1 - 0.045 14.1 0.0 0.045 14.1 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain betaPIX_CC PF16523.5 EPE28653.1 - 3.6 7.5 21.1 0.13 12.1 2.5 4.0 2 1 1 3 3 3 0 betaPIX coiled coil AAA_22 PF13401.6 EPE28653.1 - 3.7 7.8 8.2 0.42 10.9 0.8 3.0 2 1 0 2 2 2 0 AAA domain Csm1_N PF18504.1 EPE28653.1 - 4.5 7.7 18.2 0.72 10.2 6.1 5.1 3 2 2 5 5 5 0 Csm1 N-terminal domain Pyr_redox_3 PF13738.6 EPE28654.1 - 3e-14 53.0 0.0 8.8e-14 51.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EPE28654.1 - 1e-13 50.6 0.0 6e-13 48.1 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EPE28654.1 - 3.6e-13 49.4 0.0 7.5e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EPE28654.1 - 3.1e-10 39.8 0.0 1.4e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE28654.1 - 2.6e-05 24.0 0.2 0.097 12.2 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE28654.1 - 5.9e-05 23.2 0.0 0.00018 21.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EPE28654.1 - 0.00032 20.0 0.1 0.00057 19.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EPE28654.1 - 0.015 14.0 0.1 0.51 9.0 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 EPE28654.1 - 0.031 13.3 0.1 0.21 10.6 0.1 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 EPE28654.1 - 0.034 13.4 0.0 30 3.7 0.0 3.1 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EPE28654.1 - 0.21 10.6 0.0 14 4.6 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_4 PF01565.23 EPE28656.1 - 2e-21 76.2 4.9 2e-21 76.2 3.3 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EPE28656.1 - 3.9e-11 42.9 0.4 9.7e-11 41.6 0.4 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF4838 PF16126.5 EPE28656.1 - 0.05 13.0 0.3 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4838) Cytokin-bind PF09265.10 EPE28656.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Zn_clus PF00172.18 EPE28657.1 - 0.0059 16.7 7.3 0.013 15.6 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE28657.1 - 0.041 12.7 0.1 0.046 12.5 0.1 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Toxin_18 PF08087.11 EPE28657.1 - 0.091 12.8 0.3 0.21 11.6 0.3 1.6 1 0 0 1 1 1 0 Conotoxin O-superfamily RTA1 PF04479.13 EPE28658.1 - 1.3e-46 158.8 12.5 2.1e-46 158.2 12.5 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF1345 PF07077.11 EPE28658.1 - 0.0041 16.8 0.7 0.0095 15.6 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1345) EF-hand_7 PF13499.6 EPE28659.1 - 8.1e-08 32.6 0.1 5.8e-07 29.9 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair WW PF00397.26 EPE28659.1 - 2.6e-05 24.2 0.3 0.0011 19.0 0.0 2.7 2 0 0 2 2 2 1 WW domain EF-hand_6 PF13405.6 EPE28659.1 - 5.4e-05 22.8 0.0 0.53 10.3 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EPE28659.1 - 0.00023 20.5 0.0 0.0083 15.6 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EPE28659.1 - 0.052 13.1 0.1 0.2 11.2 0.1 2.1 1 0 0 1 1 1 0 EF hand Cyt_c_ox_IV PF12270.8 EPE28660.1 - 0.68 10.1 9.5 0.6 10.2 0.2 3.1 3 1 0 3 3 3 0 Cytochrome c oxidase subunit IV DEAD PF00270.29 EPE28662.1 - 1.7e-44 151.7 0.0 5.6e-42 143.5 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE28662.1 - 2.3e-24 85.9 0.0 5.7e-21 74.9 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE28662.1 - 4.2e-06 26.9 0.0 6.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EPE28662.1 - 0.14 12.4 0.0 0.55 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain WSC PF01822.19 EPE28663.1 - 2.7e-76 251.8 97.2 2.1e-17 63.1 11.9 7.2 6 1 0 6 6 6 5 WSC domain PQQ_3 PF13570.6 EPE28663.1 - 0.0027 18.1 14.6 0.028 14.9 0.1 5.1 5 0 0 5 5 5 2 PQQ-like domain PepSY PF03413.19 EPE28663.1 - 0.15 12.6 0.5 0.35 11.5 0.5 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain FAD_binding_3 PF01494.19 EPE28664.1 - 1.1e-78 264.9 0.0 1.5e-78 264.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EPE28664.1 - 1.4e-46 158.6 0.0 2.6e-46 157.7 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 EPE28664.1 - 0.0047 17.1 1.4 0.025 14.8 0.1 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE28664.1 - 0.0051 16.1 0.1 0.018 14.2 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EPE28664.1 - 0.0055 15.8 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase PALP PF00291.25 EPE28664.1 - 0.021 14.3 0.0 0.34 10.3 0.0 2.3 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme FAD_binding_2 PF00890.24 EPE28664.1 - 0.031 13.4 0.0 0.066 12.3 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EPE28664.1 - 0.034 13.4 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 EPE28664.1 - 0.066 12.5 0.5 0.16 11.3 0.1 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase MFS_1 PF07690.16 EPE28666.1 - 7e-30 104.1 30.6 7e-30 104.1 30.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EPE28667.1 - 1e-39 136.5 53.7 1e-39 136.5 53.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE28667.1 - 6.8e-10 38.0 23.6 9.1e-10 37.6 23.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_1 PF00232.18 EPE28668.1 - 2.2e-114 382.4 1.7 3.4e-114 381.8 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_10 PF00331.20 EPE28668.1 - 0.12 11.5 0.0 5.8 6.0 0.0 2.3 2 1 0 2 2 2 0 Glycosyl hydrolase family 10 Activator_LAG-3 PF11498.8 EPE28669.1 - 0.035 13.1 13.1 0.045 12.7 13.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 MAP17 PF15807.5 EPE28669.1 - 0.24 11.7 14.2 0.42 10.8 14.2 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RIBIOP_C PF04950.12 EPE28669.1 - 1.8 8.0 8.6 2.6 7.4 8.6 1.3 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal ADIP PF11559.8 EPE28669.1 - 2.4 8.2 24.0 5.7 7.0 24.0 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding LMBR1 PF04791.16 EPE28669.1 - 2.9 6.7 7.9 3.3 6.5 7.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_S46 PF10459.9 EPE28669.1 - 3.5 6.1 12.2 4.3 5.8 12.2 1.1 1 0 0 1 1 1 0 Peptidase S46 zf_C2H2_10 PF18414.1 EPE28669.1 - 5.3 6.7 9.5 7.1 6.3 1.7 2.8 2 1 1 3 3 3 0 C2H2 type zinc-finger PIN_12 PF16289.5 EPE28669.1 - 5.3 7.5 10.1 7.9 6.9 10.1 1.2 1 0 0 1 1 1 0 PIN domain AAA_11 PF13086.6 EPE28669.1 - 6.3 6.5 12.9 8.4 6.1 12.9 1.2 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 EPE28669.1 - 6.6 5.4 10.9 8.2 5.1 10.9 1.1 1 0 0 1 1 1 0 Presenilin DnaJ PF00226.31 EPE28670.1 - 2.6e-19 69.1 1.0 4.3e-19 68.4 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3450 PF11932.8 EPE28670.1 - 0.0027 17.0 0.4 0.0027 17.0 0.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 EPE28670.1 - 0.057 13.6 3.2 0.075 13.3 1.3 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Tyrosinase PF00264.20 EPE28671.1 - 5.6e-47 160.9 0.0 1e-46 160.0 0.0 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase Josephin PF02099.17 EPE28671.1 - 0.09 12.9 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Josephin DEAD PF00270.29 EPE28672.1 - 3.5e-16 59.5 0.0 8.7e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EPE28672.1 - 1.2e-10 41.6 0.0 3.4e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EPE28672.1 - 1.3e-08 35.1 0.1 4.7e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhoH PF02562.16 EPE28672.1 - 0.023 14.1 0.0 0.08 12.4 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein MBD PF01429.19 EPE28672.1 - 0.1 12.3 0.0 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 Methyl-CpG binding domain Fungal_trans_2 PF11951.8 EPE28673.1 - 5.5e-10 38.6 1.3 7.1e-10 38.2 0.6 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain E1-E2_ATPase PF00122.20 EPE28674.1 - 1.9e-39 135.1 15.8 1.4e-32 112.7 0.0 3.4 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EPE28674.1 - 2.5e-30 105.6 4.4 5.1e-30 104.5 2.6 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EPE28674.1 - 1.5e-21 76.2 0.0 4.4e-21 74.8 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EPE28674.1 - 1.8e-20 74.1 0.1 7.1e-16 59.1 0.1 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EPE28674.1 - 2.4e-15 55.9 0.0 9.1e-15 54.1 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EPE28674.1 - 8.9e-07 28.9 1.0 0.008 15.9 1.1 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EPE28674.1 - 0.17 12.3 0.0 0.42 11.0 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peroxidase_2 PF01328.17 EPE28675.1 - 0.00015 22.4 0.0 0.00023 21.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 FSH1 PF03959.13 EPE28676.1 - 4.8e-31 108.1 0.0 6e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EPE28676.1 - 0.0075 16.9 0.1 0.013 16.1 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Transferase PF02458.15 EPE28677.1 - 3.7e-21 75.3 0.0 2e-19 69.6 0.0 2.0 2 0 0 2 2 2 2 Transferase family FAD_binding_3 PF01494.19 EPE28678.1 - 1.1e-14 54.5 3.4 8.9e-12 44.9 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.6 EPE28678.1 - 3.7e-05 23.7 0.0 7.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 EPE28678.1 - 6.5e-05 22.7 0.4 0.00038 20.1 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE28678.1 - 9.8e-05 21.7 0.6 0.0016 17.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE28678.1 - 0.00016 21.8 0.4 0.00099 19.3 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EPE28678.1 - 0.0088 16.6 0.2 0.024 15.2 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE28678.1 - 0.0097 15.0 0.1 0.35 9.9 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EPE28678.1 - 0.017 14.2 0.5 0.026 13.6 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain SE PF08491.10 EPE28678.1 - 0.087 11.9 0.0 0.57 9.2 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.14 EPE28678.1 - 0.13 11.0 0.5 0.18 10.5 0.5 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EPE28678.1 - 0.21 10.8 0.5 1.4 8.1 0.9 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.23 EPE28679.1 - 1.9e-19 69.8 2.3 3.2e-19 69.0 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE28679.1 - 1.2e-07 31.7 0.1 3.2e-07 30.3 0.1 1.8 1 0 0 1 1 1 1 Berberine and berberine like Zn_clus PF00172.18 EPE28680.1 - 0.017 15.3 12.2 0.032 14.4 12.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 EPE28681.1 - 2.8e-69 233.5 0.6 7.6e-69 232.1 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain HTH_51 PF18558.1 EPE28681.1 - 6.4e-34 115.7 0.1 1.5e-33 114.5 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Ketoacyl-synt_C PF02801.22 EPE28681.1 - 4.5e-31 107.3 0.0 1.1e-30 106.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EPE28681.1 - 3.9e-28 98.3 0.0 7e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EPE28681.1 - 6.7e-24 84.0 5.6 1e-12 48.2 0.1 3.7 3 0 0 3 3 3 2 Phosphopantetheine attachment site Acyl_transf_1 PF00698.21 EPE28681.1 - 1.2e-21 77.5 0.1 1.1e-18 67.9 0.0 2.4 2 0 0 2 2 2 2 Acyl transferase domain Methyltransf_12 PF08242.12 EPE28681.1 - 3.3e-15 56.6 0.0 1e-14 55.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PS-DH PF14765.6 EPE28681.1 - 7.5e-12 45.1 0.0 1.3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase SAT PF16073.5 EPE28681.1 - 1.1e-10 41.7 2.6 5.5e-08 32.8 0.0 3.3 4 0 0 4 4 4 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_25 PF13649.6 EPE28681.1 - 6.2e-09 36.4 0.0 2.4e-08 34.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE28681.1 - 1.2e-07 32.3 0.0 3.5e-07 30.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EPE28681.1 - 1.3e-07 32.0 0.2 5.7e-07 30.0 0.0 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 EPE28681.1 - 2e-07 31.0 0.0 9.5e-07 28.8 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain Epimerase PF01370.21 EPE28681.1 - 2.8e-06 27.0 0.0 8.5e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.6 EPE28681.1 - 3.2e-06 27.0 0.0 8.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EPE28681.1 - 0.00014 21.3 1.5 0.00084 18.8 0.1 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain KR PF08659.10 EPE28681.1 - 0.018 15.0 0.0 0.047 13.6 0.0 1.7 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 EPE28681.1 - 0.061 12.5 0.0 0.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ADH_N PF08240.12 EPE28682.1 - 3.9e-08 33.1 0.0 4e-07 29.9 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE28682.1 - 9.5e-08 32.1 0.1 4e-07 30.1 0.0 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase FMO-like PF00743.19 EPE28683.1 - 1.1e-17 63.7 0.0 4.5e-13 48.5 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EPE28683.1 - 2.9e-15 56.3 0.0 4.8e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPE28683.1 - 3.4e-10 39.6 0.0 8.7e-09 35.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPE28683.1 - 1.6e-08 34.1 0.0 8.2e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EPE28683.1 - 7.6e-07 29.3 0.1 0.00027 21.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EPE28683.1 - 4.5e-05 22.8 0.1 0.00025 20.4 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 EPE28683.1 - 0.002 18.6 0.1 2.8 8.5 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE28683.1 - 0.022 14.4 0.0 0.15 11.6 0.0 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase Mqo PF06039.15 EPE28683.1 - 0.047 12.2 0.0 3.6 6.0 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) AlaDh_PNT_C PF01262.21 EPE28683.1 - 0.084 12.2 0.0 0.72 9.1 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EPE28683.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 EPE28683.1 - 0.11 11.5 0.1 5.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EPE28683.1 - 0.22 10.9 0.0 0.43 9.9 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase MFS_1 PF07690.16 EPE28684.1 - 3.9e-40 137.9 48.7 3.9e-40 137.9 48.7 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE28684.1 - 1.2e-11 43.8 24.2 1.7e-11 43.3 23.5 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EPE28685.1 - 8.9e-33 113.7 56.4 1.3e-32 113.1 39.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE28685.1 - 6e-12 45.2 16.5 6e-12 45.2 16.5 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter FAD_binding_4 PF01565.23 EPE28686.1 - 1.5e-27 96.1 1.6 1.5e-27 96.1 1.6 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EPE28686.1 - 7.7e-07 29.1 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans PF04082.18 EPE28687.1 - 2.9e-14 52.8 4.6 5.2e-14 51.9 4.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE28687.1 - 1.2e-09 38.2 7.2 2.2e-09 37.3 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0565 PF10561.9 EPE28688.1 - 0.064 12.4 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 tRNA-synt_2c PF01411.19 EPE28690.1 - 1.4e-09 37.1 0.0 1.7e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EPE28690.1 - 0.0045 17.1 1.1 0.0085 16.2 1.1 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Fungal_trans_2 PF11951.8 EPE28692.1 - 4.2e-14 52.2 0.2 9.6e-14 51.0 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Epiglycanin_C PF14654.6 EPE28693.1 - 0.0046 17.0 0.2 0.014 15.4 0.2 1.9 1 0 0 1 1 1 1 Mucin, catalytic, TM and cytoplasmic tail region Elf1 PF05129.13 EPE28694.1 - 0.013 15.6 0.2 0.015 15.3 0.2 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like HET PF06985.11 EPE28695.1 - 1.1e-36 126.4 0.0 2.4e-36 125.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SUFU PF05076.13 EPE28695.1 - 0.16 12.0 0.0 0.62 10.0 0.0 1.9 2 0 0 2 2 2 0 Suppressor of fused protein (SUFU) Bac_luciferase PF00296.20 EPE28696.1 - 5.9e-67 226.3 0.0 7.3e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase p450 PF00067.22 EPE28698.1 - 8.6e-43 146.7 0.0 4.3e-42 144.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EPE28699.1 - 5.8e-31 107.7 0.0 9.7e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 PP-binding PF00550.25 EPE28700.1 - 2.2e-09 37.5 0.1 4.2e-09 36.6 0.1 1.5 1 1 1 2 2 2 1 Phosphopantetheine attachment site ketoacyl-synt PF00109.26 EPE28701.1 - 5.5e-57 193.2 0.0 9e-57 192.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EPE28701.1 - 1.3e-54 185.5 0.0 2.1e-54 184.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EPE28701.1 - 3e-41 142.0 0.3 1.7e-39 136.2 0.3 2.3 1 1 0 1 1 1 1 Acyl transferase domain KAsynt_C_assoc PF16197.5 EPE28701.1 - 1.7e-27 96.1 0.0 4.2e-27 94.8 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Ketoacyl-synt_C PF02801.22 EPE28701.1 - 1.8e-23 82.8 0.2 1.2e-17 64.0 0.0 2.4 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EPE28701.1 - 3e-19 69.6 0.0 7.4e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE28701.1 - 2.3e-12 47.4 0.0 8.2e-12 45.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE28701.1 - 7.1e-11 42.6 0.0 3.1e-10 40.6 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE28701.1 - 1.6e-10 41.1 0.0 3.4e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE28701.1 - 7.7e-08 32.3 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE28701.1 - 0.00029 20.3 0.0 0.00052 19.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 EPE28701.1 - 0.00059 19.5 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.9 EPE28701.1 - 0.0061 16.3 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase NodS PF05401.11 EPE28701.1 - 0.0067 16.1 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Thiolase_N PF00108.23 EPE28701.1 - 0.0075 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.20 EPE28701.1 - 0.0085 15.2 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase ACP_syn_III PF08545.10 EPE28701.1 - 0.088 12.7 0.2 0.24 11.3 0.2 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PCMT PF01135.19 EPE28701.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Abhydrolase_3 PF07859.13 EPE28702.1 - 4.8e-09 36.4 0.1 1.1e-08 35.2 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EPE28702.1 - 0.00018 20.6 0.0 0.00026 20.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 EPE28702.1 - 0.0031 17.0 0.0 0.058 12.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.28 EPE28702.1 - 0.005 15.8 0.0 0.02 13.8 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase PF07224.11 EPE28702.1 - 0.008 15.2 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.16 EPE28702.1 - 0.042 13.6 0.0 0.59 9.9 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EPE28702.1 - 0.092 12.0 0.1 0.55 9.5 0.0 2.0 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Ribonuclease_T2 PF00445.18 EPE28703.1 - 1.5e-37 129.6 0.1 2e-37 129.2 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family SNO PF01174.19 EPE28704.1 - 1.8e-50 171.4 0.0 1.4e-40 139.1 0.0 2.1 1 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EPE28704.1 - 7e-08 32.3 0.0 5.3e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EPE28704.1 - 0.00025 20.9 0.0 0.0033 17.2 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 EPE28704.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Acyltransferase PF01553.21 EPE28705.1 - 2.2e-33 114.8 0.0 3.9e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase AAA PF00004.29 EPE28706.1 - 4.8e-18 65.9 0.0 9e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE28706.1 - 0.00016 22.1 0.0 0.00035 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPE28706.1 - 0.0022 18.3 0.2 0.087 13.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EPE28706.1 - 0.0072 16.3 0.0 0.03 14.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Torsin PF06309.11 EPE28706.1 - 0.011 15.8 0.1 0.19 11.8 0.1 2.3 2 0 0 2 2 2 0 Torsin AAA_33 PF13671.6 EPE28706.1 - 0.03 14.5 0.0 0.087 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain zf-CCCH_3 PF15663.5 EPE28706.1 - 0.034 14.4 0.0 0.083 13.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger containing family Clr5 PF14420.6 EPE28707.1 - 2.2e-16 59.8 2.8 4.8e-16 58.7 2.8 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 EPE28707.1 - 1.8e-11 44.1 1.1 7.3e-05 23.0 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EPE28707.1 - 0.00063 19.5 0.0 0.12 12.3 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 EPE28707.1 - 0.0051 16.5 0.5 0.011 15.5 0.5 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 EPE28707.1 - 0.048 13.7 0.1 0.54 10.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EPE28707.1 - 0.09 13.0 0.6 0.67 10.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Zn_clus PF00172.18 EPE28709.1 - 0.00043 20.3 12.3 0.00092 19.3 12.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 EPE28709.1 - 0.68 10.9 0.1 0.68 10.9 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger PHO4 PF01384.20 EPE28710.1 - 1.1e-98 330.4 21.1 1.3e-98 330.2 21.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family DUF1084 PF06454.11 EPE28710.1 - 0.039 13.3 0.6 2.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1084) FAD_binding_3 PF01494.19 EPE28711.1 - 1.3e-16 60.8 0.0 5.8e-13 48.8 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 EPE28711.1 - 1.5e-07 31.4 1.2 0.0027 17.3 0.4 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EPE28711.1 - 3.6e-05 23.3 0.3 0.0041 16.5 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EPE28711.1 - 0.00015 21.0 0.1 0.2 10.7 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EPE28711.1 - 0.00026 20.3 0.6 0.015 14.5 0.4 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE28711.1 - 0.0015 18.7 0.4 0.0036 17.5 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EPE28711.1 - 0.0021 17.4 0.0 1.3 8.2 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EPE28711.1 - 0.011 14.8 0.0 0.48 9.4 0.0 2.4 3 0 0 3 3 3 0 Squalene epoxidase NAD_binding_9 PF13454.6 EPE28711.1 - 0.015 15.3 0.2 4.5 7.3 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EPE28711.1 - 0.023 13.4 0.0 2.4 6.8 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein 3HCDH_N PF02737.18 EPE28711.1 - 0.045 13.6 0.3 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EPE28711.1 - 0.048 14.2 0.1 7.6 7.2 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase YCII PF03795.14 EPE28712.1 - 0.043 14.2 0.0 0.074 13.5 0.0 1.4 1 1 0 1 1 1 0 YCII-related domain NUDIX_4 PF14815.6 EPE28712.1 - 0.063 13.3 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain Urb2 PF10441.9 EPE28712.1 - 0.16 11.9 0.0 0.17 11.8 0.0 1.0 1 0 0 1 1 1 0 Urb2/Npa2 family Tim17 PF02466.19 EPE28715.1 - 4.7e-26 91.3 3.5 6.4e-26 90.9 3.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2428 PF10350.9 EPE28716.1 - 6e-61 206.1 10.7 2.8e-60 203.9 5.1 2.9 3 0 0 3 3 3 2 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 EPE28716.1 - 7.5e-11 41.3 5.7 0.0088 16.2 0.0 6.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 EPE28716.1 - 0.00099 19.4 9.3 0.93 9.9 0.6 6.2 6 1 1 7 7 7 2 HEAT repeats NT5C PF06941.12 EPE28716.1 - 0.0019 18.1 0.1 0.018 14.9 0.0 2.6 3 0 0 3 3 3 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HEAT_EZ PF13513.6 EPE28716.1 - 0.0028 18.1 4.7 24 5.6 0.1 6.0 5 1 1 6 6 6 1 HEAT-like repeat Ribosomal_L19e PF01280.20 EPE28718.1 - 0.012 15.6 3.7 0.027 14.5 3.7 1.6 1 0 0 1 1 1 0 Ribosomal protein L19e Spem1 PF15670.5 EPE28718.1 - 0.36 10.4 8.0 1.1 8.8 2.6 2.1 2 0 0 2 2 2 0 Spermatid maturation protein 1 LAP1C PF05609.12 EPE28718.1 - 1.5 7.8 5.2 0.39 9.8 1.9 1.6 1 1 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Amnionless PF14828.6 EPE28719.1 - 0.005 15.7 0.0 0.0059 15.5 0.0 1.1 1 0 0 1 1 1 1 Amnionless Pox_A14 PF05767.12 EPE28719.1 - 0.047 13.8 0.1 0.078 13.1 0.1 1.3 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 Ni_hydr_CYTB PF01292.20 EPE28719.1 - 0.077 12.6 0.0 0.083 12.5 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 PX PF00787.24 EPE28721.1 - 3.4e-19 68.9 0.0 9.9e-19 67.4 0.0 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EPE28721.1 - 8e-11 41.9 5.0 0.0001 22.0 0.1 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.9 EPE28721.1 - 0.071 12.6 0.0 0.44 10.0 0.1 2.0 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein ATP-synt_E PF05680.12 EPE28721.1 - 0.24 11.7 0.1 0.24 11.7 0.1 2.3 2 0 0 2 2 2 0 ATP synthase E chain Mito_carr PF00153.27 EPE28722.1 - 3.7e-47 158.2 0.1 7.1e-16 57.9 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.7 EPE28722.1 - 0.082 13.4 2.2 18 6.0 0.0 3.2 3 0 0 3 3 3 0 YtxH-like protein zf-NOSIP PF15906.5 EPE28723.1 - 1.6e-10 41.0 0.0 3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EPE28723.1 - 1.6e-06 28.0 12.4 2.6e-05 24.1 4.4 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 EPE28723.1 - 1.7e-06 28.3 15.3 3.8e-05 23.9 4.3 3.0 3 1 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 EPE28723.1 - 4.5e-06 26.5 4.2 4.5e-06 26.5 4.2 2.9 2 2 0 2 2 2 1 zinc-RING finger domain Rtf2 PF04641.12 EPE28723.1 - 1.8e-05 24.3 3.4 1.8e-05 24.3 3.4 2.9 1 1 2 3 3 3 1 Rtf2 RING-finger zf-C3HC4_3 PF13920.6 EPE28723.1 - 5.2e-05 23.0 14.8 0.0019 18.0 5.9 3.1 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE28723.1 - 0.00012 21.8 13.8 0.00041 20.1 1.5 2.8 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE28723.1 - 0.00062 19.6 2.0 0.00062 19.6 2.0 2.9 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 EPE28723.1 - 0.0012 18.9 1.3 0.0012 18.9 1.3 2.6 2 1 0 2 2 2 1 FYVE zinc finger zf-C3HC4_4 PF15227.6 EPE28723.1 - 0.051 13.7 14.2 1.3 9.3 1.6 3.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_5 PF17121.5 EPE28723.1 - 1.2 9.1 5.4 0.19 11.6 1.3 1.9 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EPE28723.1 - 1.9 8.4 7.2 0.086 12.7 0.6 2.3 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EPE28723.1 - 5.7 6.9 21.8 0.3 11.0 6.8 3.6 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 Acyltransferase PF01553.21 EPE28724.1 - 1.2e-13 50.8 0.0 3.9e-13 49.2 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase Mucin15 PF15672.5 EPE28725.1 - 0.012 15.1 2.4 0.012 15.1 2.4 1.9 2 1 0 2 2 2 0 Cell-membrane associated Mucin15 Glyco_hydro_2_C PF02836.17 EPE28727.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Hydrolase_4 PF12146.8 EPE28728.1 - 1.3e-07 31.2 0.0 0.00059 19.2 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EPE28728.1 - 3.2e-06 26.8 0.1 0.017 14.6 0.1 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EPE28728.1 - 3.4e-05 23.6 0.0 5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 EPE28728.1 - 0.00016 21.3 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EPE28728.1 - 0.0005 20.7 0.2 0.0011 19.6 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.11 EPE28728.1 - 0.0018 18.2 0.0 0.0071 16.3 0.0 1.8 2 0 0 2 2 2 1 Bacterial virulence protein (VirJ) DUF915 PF06028.11 EPE28728.1 - 0.009 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_7 PF12715.7 EPE28728.1 - 0.011 15.0 0.0 2.2 7.4 0.0 2.1 1 1 1 2 2 2 0 Abhydrolase family PhoPQ_related PF10142.9 EPE28728.1 - 0.27 9.9 0.1 0.4 9.3 0.1 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein MFS_1 PF07690.16 EPE28729.1 - 5.6e-36 124.2 46.9 2.5e-35 122.1 32.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MARVEL PF01284.23 EPE28730.1 - 3.2e-09 37.0 17.3 1.7e-08 34.6 17.2 1.9 1 1 0 1 1 1 1 Membrane-associating domain Hum_adeno_E3A PF05393.11 EPE28730.1 - 0.17 11.9 2.1 3.3 7.7 0.5 2.2 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Cytochrome_B PF00033.19 EPE28730.1 - 0.48 10.2 8.3 0.13 12.1 4.9 1.7 2 0 0 2 2 2 0 Cytochrome b/b6/petB Cas6b_C PF17262.2 EPE28731.1 - 0.071 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Cas6b C-terminal domain ILVD_EDD PF00920.21 EPE28733.1 - 1e-210 700.8 0.3 1.1e-210 700.6 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 EPE28733.1 - 0.0028 17.9 0.1 0.018 15.3 0.0 2.3 3 0 0 3 3 3 1 5'-nucleotidase, C-terminal domain Peptidase_M14 PF00246.24 EPE28734.1 - 4e-39 135.1 0.2 5.3e-39 134.7 0.2 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase C1_1 PF00130.22 EPE28735.1 - 0.0057 16.5 0.6 0.013 15.4 0.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SAGA-Tad1 PF12767.7 EPE28736.1 - 0.15 11.8 1.6 0.48 10.1 1.6 1.7 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Collagen PF01391.18 EPE28737.1 - 0.0035 17.1 6.5 0.0082 15.9 6.5 1.6 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Glyco_hydro_12 PF01670.16 EPE28738.1 - 4.2e-53 180.5 7.1 5e-53 180.3 7.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Ecl1 PF12855.7 EPE28739.1 - 2.2e-19 71.3 41.7 1.3e-17 65.5 41.7 2.1 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins BTB PF00651.31 EPE28740.1 - 5.8e-08 32.9 0.2 0.00016 21.9 0.0 2.9 2 1 1 3 3 3 2 BTB/POZ domain Ferlin_C PF16165.5 EPE28741.1 - 5.2 7.0 7.3 8.6 6.3 7.3 1.6 1 1 0 1 1 1 0 Ferlin C-terminus 2OG-FeII_Oxy_3 PF13640.6 EPE28744.1 - 1.8e-12 48.0 0.0 2.9e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HET PF06985.11 EPE28747.1 - 2.7e-05 24.5 0.0 5.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2855 PF11017.8 EPE28748.1 - 6.8e-102 341.7 0.0 7.8e-102 341.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) SopA PF13981.6 EPE28748.1 - 0.042 14.3 0.0 0.073 13.5 0.0 1.4 1 0 0 1 1 1 0 SopA-like central domain mRNA_cap_enzyme PF01331.19 EPE28749.1 - 3.2e-53 180.5 0.0 5.4e-53 179.7 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EPE28749.1 - 4.7e-34 117.3 0.1 8e-34 116.5 0.1 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EPE28749.1 - 1.3e-07 31.5 0.0 5.1e-05 23.0 0.0 2.5 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EPE28749.1 - 0.00051 20.4 0.0 0.00087 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DUF1357 PF07094.11 EPE28749.1 - 0.05 13.7 0.5 0.078 13.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) Iwr1 PF08574.10 EPE28751.1 - 7e-15 55.8 9.2 7e-15 55.8 9.2 2.9 3 0 0 3 3 3 1 Transcription factor Iwr1 DUF4598 PF15370.6 EPE28751.1 - 0.016 15.7 3.0 0.037 14.5 3.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) E7 PF00527.18 EPE28751.1 - 0.49 10.6 1.4 1.1 9.6 1.4 1.6 1 0 0 1 1 1 0 E7 protein, Early protein ABC2_membrane PF01061.24 EPE28752.1 - 1.4e-84 282.8 40.5 8e-47 159.4 16.7 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EPE28752.1 - 3.5e-41 140.9 0.0 8.1e-20 71.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EPE28752.1 - 2.2e-29 101.2 8.0 4e-27 93.9 0.1 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 EPE28752.1 - 1.7e-11 43.9 34.0 4.2e-09 36.0 14.7 2.4 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 EPE28752.1 - 1.1e-10 41.9 0.1 4e-10 40.2 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EPE28752.1 - 9.1e-06 26.1 0.3 0.0032 17.9 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EPE28752.1 - 0.00012 21.7 0.2 0.0034 17.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPE28752.1 - 0.00021 21.6 0.4 0.56 10.5 0.2 3.2 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EPE28752.1 - 0.00032 20.6 0.3 0.002 18.0 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EPE28752.1 - 0.00036 20.2 0.4 0.066 13.0 0.1 3.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EPE28752.1 - 0.00086 19.9 0.0 1.4 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EPE28752.1 - 0.0022 17.9 0.0 2.9 7.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 EPE28752.1 - 0.0026 18.0 0.9 1 9.6 0.4 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EPE28752.1 - 0.0054 16.3 1.1 1.8 8.1 0.5 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EPE28752.1 - 0.013 15.7 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EPE28752.1 - 0.02 14.6 0.2 4.5 6.9 0.3 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EPE28752.1 - 0.021 14.6 0.1 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EPE28752.1 - 0.044 13.7 0.7 3.2 7.6 0.3 2.4 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 EPE28752.1 - 0.065 13.2 0.0 3.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA PF00004.29 EPE28752.1 - 0.12 12.8 0.0 20 5.6 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 EPE28752.1 - 0.22 11.3 0.3 9 6.0 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Glyco_hydro_6 PF01341.17 EPE28753.1 - 1.1e-97 327.4 0.8 1.4e-97 327.1 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 zf-MYND PF01753.18 EPE28755.1 - 2.1e-08 34.1 5.8 3.6e-08 33.4 5.8 1.4 1 0 0 1 1 1 1 MYND finger EMC3_TMCO1 PF01956.16 EPE28755.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4360 PF14273.6 EPE28756.1 - 1e-66 224.2 3.8 1.1e-66 224.0 3.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Abhydrolase_1 PF00561.20 EPE28757.1 - 4.8e-21 75.5 0.3 1.3e-20 74.2 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE28757.1 - 4.4e-13 50.3 1.5 6e-13 49.9 1.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE28757.1 - 2.8e-07 30.1 0.0 3.5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Fungal_trans PF04082.18 EPE28758.1 - 4.3e-16 58.7 0.1 1e-15 57.5 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE28758.1 - 2.8e-08 33.8 11.9 4.8e-08 33.0 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE28759.1 - 4e-13 49.0 0.0 8.4e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE28759.1 - 0.00027 21.0 1.1 0.00056 20.0 1.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_1 PF00190.22 EPE28760.1 - 8.6e-41 139.0 0.0 1.8e-19 69.8 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EPE28760.1 - 2e-23 81.9 0.7 1.8e-10 40.4 0.1 3.0 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 EPE28760.1 - 2e-10 40.2 0.1 0.00013 21.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 EPE28760.1 - 8.8e-09 35.4 0.0 6e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 EPE28760.1 - 1.4e-05 25.0 0.0 8.3e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_4 PF08007.12 EPE28760.1 - 0.016 14.7 0.0 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein ARD PF03079.14 EPE28760.1 - 0.025 14.8 0.1 2 8.6 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family 3-HAO PF06052.12 EPE28760.1 - 0.036 13.7 0.0 0.095 12.3 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Cupin_8 PF13621.6 EPE28760.1 - 0.1 12.3 0.0 0.7 9.6 0.0 2.1 2 0 0 2 2 2 0 Cupin-like domain Zn_clus PF00172.18 EPE28761.1 - 1.7e-06 28.0 9.6 4.1e-06 26.8 9.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDH-cyt PF16010.5 EPE28763.1 - 2.2e-47 161.1 7.4 2.2e-47 161.1 7.4 2.0 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase Fungal_trans PF04082.18 EPE28765.1 - 6.6e-13 48.3 0.3 1.1e-12 47.6 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpes_UL92 PF03048.14 EPE28768.1 - 0.0086 15.9 0.2 0.019 14.8 0.0 1.5 2 0 0 2 2 2 1 UL92 family AIF_C PF14721.6 EPE28768.1 - 0.057 13.8 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3592 PF12158.8 EPE28770.1 - 0.0088 16.1 0.0 0.016 15.3 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3592) NicO PF03824.16 EPE28771.1 - 8.7e-59 199.2 10.8 8.7e-59 199.2 10.8 1.5 2 0 0 2 2 2 1 High-affinity nickel-transport protein DUF4229 PF14012.6 EPE28771.1 - 0.12 12.5 0.2 0.12 12.5 0.2 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4229) NOA36 PF06524.12 EPE28772.1 - 3.8 6.7 8.4 4.4 6.5 8.4 1.1 1 0 0 1 1 1 0 NOA36 protein Histone PF00125.24 EPE28773.1 - 0.0072 16.7 1.8 0.01 16.2 1.7 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 MPP6 PF10175.9 EPE28773.1 - 0.051 14.1 2.0 0.061 13.8 1.0 1.5 2 0 0 2 2 2 0 M-phase phosphoprotein 6 Abhydrolase_1 PF00561.20 EPE28774.1 - 2.1e-29 103.0 0.0 2.6e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE28774.1 - 3.5e-16 60.5 0.0 5.8e-16 59.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE28774.1 - 6.6e-10 38.7 0.0 8.9e-08 31.7 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PsbN PF02468.15 EPE28774.1 - 0.09 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Ndr PF03096.14 EPE28774.1 - 0.13 10.9 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family Pinin_SDK_memA PF04696.13 EPE28775.1 - 3.2e-34 117.8 14.4 3.2e-34 117.8 14.4 2.3 3 1 1 4 4 4 1 pinin/SDK/memA/ protein conserved region PHF5 PF03660.14 EPE28776.1 - 4.6e-52 174.6 10.6 5.1e-52 174.4 10.6 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EPE28776.1 - 0.47 8.2 7.2 0.48 8.2 7.2 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EPE28776.1 - 4 7.5 16.3 7 6.8 2.3 3.0 1 1 1 2 2 2 0 Double zinc ribbon Peptidase_M24 PF00557.24 EPE28777.1 - 9.6e-08 32.0 0.0 1.9e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 SNF5 PF04855.12 EPE28778.1 - 8.7e-63 212.3 0.0 1.3e-61 208.4 0.0 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 CI-B14_5a PF07347.12 EPE28778.1 - 0.057 13.3 1.3 0.16 11.8 0.5 2.2 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) DUF4965 PF16335.5 EPE28779.1 - 5.3e-72 241.1 0.0 1e-71 240.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EPE28779.1 - 2.2e-62 210.8 3.7 4e-62 210.0 3.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 EPE28779.1 - 7.9e-38 130.5 6.2 4e-27 95.7 0.7 2.8 1 1 1 2 2 2 2 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EPE28779.1 - 0.001 18.6 4.0 0.0036 16.8 0.5 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4964) Bac_rhamnosid6H PF17389.2 EPE28779.1 - 0.0011 18.3 0.3 0.0032 16.8 0.2 1.7 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain MOSC PF03473.17 EPE28780.1 - 2.4e-21 76.1 0.0 1.5e-20 73.5 0.0 2.3 2 0 0 2 2 2 1 MOSC domain Fer2 PF00111.27 EPE28780.1 - 7.5e-10 38.6 1.9 1.5e-09 37.7 1.9 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.21 EPE28780.1 - 0.00074 20.1 0.0 0.018 15.7 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain 3-alpha PF03475.14 EPE28780.1 - 0.0099 15.7 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 3-alpha domain Ank_2 PF12796.7 EPE28782.1 - 5.5e-23 81.4 0.0 8.3e-08 32.7 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE28782.1 - 1.6e-14 52.6 0.1 8.9e-05 22.6 0.0 6.0 6 1 1 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EPE28782.1 - 3.1e-12 46.5 1.1 0.00062 20.0 0.0 5.4 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPE28782.1 - 1.3e-10 41.6 0.1 0.00016 22.1 0.0 4.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EPE28782.1 - 2.5e-06 27.7 0.7 0.055 13.9 0.0 5.5 6 1 0 6 6 6 1 Ankyrin repeat BBS2_Mid PF14783.6 EPE28782.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region RNase_H PF00075.24 EPE28784.1 - 2.2e-06 27.9 0.0 3.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 RNase H SnoaL PF07366.12 EPE28785.1 - 7e-23 80.8 0.0 7.9e-23 80.6 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EPE28785.1 - 3e-10 40.6 0.1 4.3e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain HEAT_2 PF13646.6 EPE28786.1 - 1.5e-05 25.3 1.3 0.0054 17.1 0.2 4.6 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 EPE28786.1 - 8.7e-05 22.5 6.0 0.15 12.4 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 EPE28786.1 - 0.00043 20.4 1.9 1.6 8.8 0.0 5.1 6 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EPE28786.1 - 0.0065 17.0 5.9 0.22 12.1 0.0 4.4 4 0 0 4 4 4 1 HEAT-like repeat Trypan_PARP PF05887.11 EPE28786.1 - 1.3 9.0 43.5 0.013 15.5 32.7 2.5 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Cu-oxidase_3 PF07732.15 EPE28788.1 - 1.4e-39 134.8 7.7 3e-39 133.7 3.6 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EPE28788.1 - 5.7e-39 133.0 6.4 1.1e-36 125.6 0.4 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EPE28788.1 - 7.9e-33 113.8 0.4 3e-32 111.9 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Ank_4 PF13637.6 EPE28790.1 - 5.4e-12 46.0 0.0 0.03 14.9 0.0 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE28790.1 - 6.6e-12 45.8 0.0 9.7e-08 32.5 0.0 3.4 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE28790.1 - 1.1e-11 43.8 0.0 0.012 16.1 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 EPE28790.1 - 6.5e-09 35.8 0.0 0.0056 17.1 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EPE28790.1 - 0.013 15.8 0.0 0.66 10.4 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) BRF1 PF07741.13 EPE28791.1 - 2.7 8.4 7.0 19 5.7 1.3 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain AA_permease PF00324.21 EPE28793.1 - 1.9e-123 412.6 43.5 2.4e-123 412.3 43.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE28793.1 - 4.8e-34 117.9 49.2 5.8e-34 117.6 49.2 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_28 PF00295.17 EPE28796.1 - 4.8e-52 177.0 3.1 6.1e-52 176.7 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Tyrosinase PF00264.20 EPE28797.1 - 3.7e-48 164.8 4.7 9.3e-48 163.4 4.7 1.7 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EPE28797.1 - 2.6e-23 83.0 0.0 4.9e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain DUF4848 PF16140.5 EPE28797.1 - 0.18 11.4 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4848) WAC_Acf1_DNA_bd PF10537.9 EPE28798.1 - 2.4e-38 130.7 0.1 2.4e-38 130.7 0.1 2.3 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EPE28798.1 - 3.7e-17 62.6 0.2 3.7e-17 62.6 0.2 3.5 4 0 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EPE28798.1 - 1e-16 60.9 3.9 1.7e-16 60.3 3.9 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EPE28798.1 - 2.3e-06 27.0 0.0 5.9e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Alg6_Alg8 PF03155.15 EPE28799.1 - 2.6e-81 274.0 8.8 3.2e-81 273.8 8.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family GT87 PF09594.10 EPE28799.1 - 0.41 10.3 10.2 0.3 10.8 7.9 2.0 2 1 0 2 2 2 0 Glycosyltransferase family 87 Lectin_leg-like PF03388.13 EPE28800.1 - 1e-27 97.0 0.0 1.4e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Phage_T7_Capsid PF05396.11 EPE28800.1 - 0.043 14.2 0.7 0.2 12.0 0.0 2.2 1 1 2 3 3 3 0 Phage T7 capsid assembly protein FlxA PF14282.6 EPE28800.1 - 0.14 12.1 2.4 0.26 11.3 2.4 1.4 1 0 0 1 1 1 0 FlxA-like protein Pex26 PF07163.12 EPE28801.1 - 0.0011 18.3 2.7 0.0023 17.3 2.7 1.5 1 0 0 1 1 1 1 Pex26 protein GAGA_bind PF06217.12 EPE28801.1 - 1.9 8.7 6.1 2.9 8.1 6.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF5401 PF17380.2 EPE28801.1 - 4.4 5.3 18.9 6.4 4.7 18.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) CAF1 PF04857.20 EPE28802.1 - 6.6e-81 271.9 0.1 7.9e-81 271.7 0.1 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 EPE28802.1 - 0.00014 21.6 0.0 0.0046 16.7 0.0 2.4 3 0 0 3 3 3 1 3'-5' exonuclease RNase_T PF00929.24 EPE28802.1 - 0.035 14.6 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 Exonuclease GH43_C PF16369.5 EPE28803.1 - 0.023 15.3 0.5 0.039 14.6 0.5 1.3 1 0 0 1 1 1 0 C-terminal lipocalin-like domain COesterase PF00135.28 EPE28804.1 - 2.5e-92 310.4 0.0 4.6e-92 309.5 0.0 1.2 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE28804.1 - 4.1e-05 23.6 0.1 0.00014 21.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_2 PF00891.18 EPE28805.1 - 6.6e-25 87.6 0.0 1e-24 87.0 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 EPE28805.1 - 5.7e-06 26.3 0.5 1.1e-05 25.3 0.5 1.5 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.20 EPE28805.1 - 0.0068 16.7 0.2 0.018 15.4 0.2 1.7 2 0 0 2 2 2 1 Transcriptional regulator Dimerisation2 PF16864.5 EPE28805.1 - 0.016 15.2 0.1 0.034 14.1 0.1 1.5 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_23 PF13489.6 EPE28805.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Arginase PF00491.21 EPE28806.1 - 8.4e-93 310.9 0.0 9.8e-93 310.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EPE28806.1 - 0.014 15.6 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 UPF0489 domain Cu_bind_like PF02298.17 EPE28807.1 - 0.00035 20.5 0.3 0.0015 18.5 0.3 2.0 1 1 0 1 1 1 1 Plastocyanin-like domain Sacchrp_dh_NADP PF03435.18 EPE28808.1 - 4.6e-16 59.3 0.0 9.7e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EPE28808.1 - 0.0055 17.1 0.0 0.018 15.5 0.0 2.0 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_L37ae PF01780.19 EPE28809.1 - 1.9e-40 136.8 10.4 2.2e-40 136.6 10.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EPE28809.1 - 0.0009 19.3 2.5 0.0009 19.3 2.5 1.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 EPE28809.1 - 0.0033 17.3 2.9 0.0058 16.6 2.9 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 EPE28809.1 - 0.0074 16.3 1.5 0.011 15.8 1.5 1.2 1 0 0 1 1 1 1 Zinc-ribbon containing domain Zn_ribbon_SprT PF17283.2 EPE28809.1 - 0.034 14.1 2.7 0.077 12.9 2.7 1.6 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Sgf11 PF08209.11 EPE28809.1 - 0.055 13.0 0.5 0.63 9.7 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Zn-ribbon_8 PF09723.10 EPE28809.1 - 0.058 13.5 0.6 0.12 12.5 0.6 1.5 1 0 0 1 1 1 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 EPE28809.1 - 0.099 12.4 2.6 0.19 11.5 0.1 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-BED PF02892.15 EPE28809.1 - 0.2 11.7 6.9 0.42 10.7 0.7 2.2 1 1 1 2 2 2 0 BED zinc finger C1_2 PF03107.16 EPE28809.1 - 0.22 11.9 2.5 6.9 7.1 3.0 2.0 1 1 1 2 2 2 0 C1 domain CarbpepA_inh PF02977.15 EPE28809.1 - 0.23 11.3 5.3 2.8 7.8 5.3 2.2 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-H2C2_2 PF13465.6 EPE28809.1 - 0.24 11.9 6.8 1.5 9.4 1.0 2.3 1 1 1 2 2 2 0 Zinc-finger double domain PHD PF00628.29 EPE28810.1 - 1.8e-10 40.6 5.5 1.8e-10 40.6 5.5 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 EPE28810.1 - 3e-08 33.9 4.1 3e-08 33.9 4.1 3.4 3 0 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 EPE28810.1 - 2.6e-06 27.2 9.6 3e-06 27.0 2.8 3.0 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EPE28810.1 - 3.6e-05 23.5 3.7 3.6e-05 23.5 3.7 3.4 3 1 2 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPE28810.1 - 8.5e-05 22.8 17.8 0.00033 20.9 8.8 3.1 3 1 0 3 3 2 2 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EPE28810.1 - 0.0002 21.4 0.8 0.0002 21.4 0.8 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EPE28810.1 - 0.00021 21.1 2.0 0.00021 21.1 2.0 3.7 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE28810.1 - 0.00038 20.3 2.3 0.00038 20.3 2.3 3.1 4 1 0 4 4 3 1 zinc-RING finger domain PHD_2 PF13831.6 EPE28810.1 - 0.00058 19.4 2.9 0.00058 19.4 2.9 2.3 2 0 0 2 2 2 1 PHD-finger zf-RING_UBOX PF13445.6 EPE28810.1 - 0.0043 17.0 3.5 0.0043 17.0 3.5 3.6 2 2 0 2 2 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EPE28810.1 - 0.0049 16.7 6.9 0.0049 16.7 6.9 3.0 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 EPE28810.1 - 0.0052 16.7 2.0 0.0052 16.7 2.0 3.5 3 1 1 4 4 4 1 Prokaryotic RING finger family 1 Rtf2 PF04641.12 EPE28810.1 - 0.0094 15.3 0.8 0.023 14.1 0.8 1.7 1 1 0 1 1 1 1 Rtf2 RING-finger Zn_ribbon_17 PF17120.5 EPE28810.1 - 0.01 15.4 3.2 0.01 15.4 3.2 2.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-PHD-like PF15446.6 EPE28810.1 - 0.027 14.1 1.6 0.14 11.8 0.2 2.6 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-Di19 PF05605.12 EPE28810.1 - 0.051 13.9 0.1 10 6.5 0.0 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CDC24_OB3 PF17244.2 EPE28810.1 - 0.49 10.1 2.8 0.4 10.4 0.5 1.8 1 1 1 2 2 2 0 Cell division control protein 24, OB domain 3 zf-RING_9 PF13901.6 EPE28810.1 - 0.89 9.5 11.5 1.5 8.8 2.0 2.5 2 1 0 2 2 2 0 Putative zinc-RING and/or ribbon FANCL_C PF11793.8 EPE28810.1 - 3.6 7.8 8.4 2 8.7 1.4 2.6 2 0 0 2 2 2 0 FANCL C-terminal domain MRP-L46 PF11788.8 EPE28811.1 - 2.2e-33 115.5 0.0 5.7e-33 114.2 0.0 1.8 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 DAO PF01266.24 EPE28812.1 - 4.8e-26 92.2 6.6 6e-26 91.9 6.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE28812.1 - 0.0031 16.8 0.1 0.27 10.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FA_desaturase PF00487.24 EPE28813.1 - 2e-21 77.0 17.8 3.8e-21 76.1 17.8 1.5 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EPE28813.1 - 0.0002 21.6 0.0 0.00047 20.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) adh_short PF00106.25 EPE28814.1 - 6.5e-17 61.6 0.0 1.8e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE28814.1 - 7.9e-10 38.7 0.0 2e-09 37.4 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE28814.1 - 0.00031 20.7 0.0 0.00048 20.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE28814.1 - 0.094 12.2 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 EPE28815.1 - 2.9e-41 141.6 25.4 1e-38 133.2 12.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EPE28815.1 - 8e-07 27.7 1.5 0.00053 18.4 3.4 2.4 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EPE28815.1 - 0.00017 20.1 5.9 0.00017 20.1 5.9 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector OAD_gamma PF04277.13 EPE28815.1 - 0.059 14.0 0.0 0.059 14.0 0.0 2.5 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain MFS_1_like PF12832.7 EPE28815.1 - 0.49 9.2 12.5 0.068 12.0 4.7 2.8 3 1 1 4 4 4 0 MFS_1 like family PUF PF00806.19 EPE28816.1 - 2e-27 93.3 0.0 3.1e-05 23.4 0.1 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EPE28816.1 - 1.4e-10 40.8 0.0 3.2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2811 PF10929.8 EPE28816.1 - 0.15 12.4 0.2 0.32 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) YL1 PF05764.13 EPE28817.1 - 2.8e-66 224.1 27.3 2.8e-66 224.1 27.3 2.4 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 EPE28817.1 - 5.3e-10 38.9 1.5 1.1e-09 37.9 1.5 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.16 EPE28817.1 - 0.0033 17.3 0.2 0.0055 16.5 0.2 1.2 1 0 0 1 1 1 1 HIT zinc finger FapA PF03961.13 EPE28817.1 - 1.5 7.4 8.7 2.3 6.7 8.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Methyltransf_31 PF13847.6 EPE28818.1 - 6.7e-29 100.6 0.0 1e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE28818.1 - 1.6e-22 80.0 0.0 3e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE28818.1 - 9.4e-20 71.1 0.0 1.9e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE28818.1 - 6.4e-15 55.1 0.0 9.6e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EPE28818.1 - 4.3e-11 42.9 0.0 1.2e-10 41.4 0.0 1.7 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE28818.1 - 1.2e-10 42.0 0.0 3e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EPE28818.1 - 4.3e-08 32.9 0.1 6.6e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EPE28818.1 - 7.1e-08 32.5 0.0 1.4e-07 31.5 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EPE28818.1 - 1.6e-05 24.6 0.1 4e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 EPE28818.1 - 3e-05 23.5 0.0 4.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 EPE28818.1 - 0.0016 18.5 0.0 0.0078 16.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 EPE28818.1 - 0.0019 18.0 0.3 0.012 15.3 0.1 2.1 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.15 EPE28818.1 - 0.0025 17.7 0.6 0.01 15.7 0.6 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.17 EPE28818.1 - 0.035 13.6 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_29 PF03141.16 EPE28818.1 - 0.2 10.2 0.0 0.31 9.5 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase HET PF06985.11 EPE28819.1 - 1.8e-29 102.9 0.0 3e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 EPE28820.1 - 1.7e-22 79.8 70.1 8.6e-20 70.9 46.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.22 EPE28821.1 - 3e-37 126.3 0.0 1.3e-11 44.1 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPE28821.1 - 8.8e-13 47.9 0.0 0.015 15.2 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM PF10378.9 EPE28821.1 - 2.1e-06 27.3 14.8 2.1e-06 27.3 14.8 4.4 3 1 1 4 4 4 1 Putative RRM domain DUF4523 PF15023.6 EPE28821.1 - 4.9e-05 23.2 0.0 0.21 11.4 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 EPE28821.1 - 0.005 16.9 0.1 4.5 7.4 0.0 3.7 4 0 0 4 4 4 1 RNA recognition motif Spo7_2_N PF15407.6 EPE28821.1 - 0.15 11.7 0.0 0.43 10.2 0.0 1.8 1 0 0 1 1 1 0 Sporulation protein family 7 RNA_bind PF08675.11 EPE28821.1 - 0.16 12.0 0.2 0.83 9.7 0.0 2.3 3 0 0 3 3 3 0 RNA binding domain RRM_3 PF08777.11 EPE28821.1 - 0.17 12.0 8.0 0.35 11.0 0.1 3.3 3 0 0 3 3 3 0 RNA binding motif tRNA-synt_2 PF00152.20 EPE28822.1 - 1.1e-84 284.2 0.0 1.7e-84 283.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EPE28822.1 - 9.5e-09 35.1 0.1 2.6e-08 33.7 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 EPE28822.1 - 0.0062 16.7 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain CDC27 PF09507.10 EPE28822.1 - 0.011 15.2 5.0 0.015 14.7 5.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Lipoprotein_16 PF03923.13 EPE28822.1 - 0.052 13.2 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized lipoprotein VIT1 PF01988.19 EPE28822.1 - 0.34 10.7 2.6 0.49 10.2 1.1 2.1 2 1 0 2 2 2 0 VIT family DNA_ligase_A_M PF01068.21 EPE28823.1 - 7.7e-57 192.2 0.4 6.9e-55 185.9 0.4 2.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EPE28823.1 - 5.3e-40 137.6 0.0 1.3e-39 136.3 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EPE28823.1 - 1.1e-28 99.7 3.1 4.3e-28 97.8 0.0 3.2 2 1 1 3 3 3 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EPE28823.1 - 6.9e-07 29.7 0.1 1.3e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 RNA ligase Dec-1 PF04624.14 EPE28824.1 - 0.22 11.4 2.5 0.71 9.8 2.5 1.9 1 0 0 1 1 1 0 Dec-1 repeat Tma16 PF11176.8 EPE28824.1 - 0.32 10.9 5.6 0.21 11.5 0.7 2.3 1 1 1 2 2 2 0 Translation machinery-associated protein 16 Ras PF00071.22 EPE28825.1 - 5e-53 179.0 0.0 6.3e-53 178.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE28825.1 - 6.8e-19 68.3 0.0 9.7e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE28825.1 - 6.1e-07 29.1 0.0 8.6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MFS_1 PF07690.16 EPE28826.1 - 7.5e-16 58.0 51.8 9.2e-10 38.0 29.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TNFR_16_TM PF18422.1 EPE28826.1 - 0.0084 16.0 0.2 0.0084 16.0 0.2 2.3 2 0 0 2 2 2 1 Tumor necrosis factor receptor member 16 trans-membrane domain Fungal_trans PF04082.18 EPE28827.1 - 7.2e-05 21.9 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE28827.1 - 0.00021 21.3 7.9 0.00039 20.5 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPE28828.1 - 4.5e-37 127.8 60.8 4.5e-37 127.8 60.8 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE28828.1 - 8.3e-12 44.7 12.1 8.3e-12 44.7 12.1 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter DUF423 PF04241.15 EPE28828.1 - 1.1 9.5 0.0 1.1 9.5 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF423) Methyltransf_2 PF00891.18 EPE28829.1 - 1.4e-20 73.5 0.0 2.3e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EPE28829.1 - 0.00059 20.5 0.0 0.0022 18.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EPE28829.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_5 PF01795.19 EPE28829.1 - 0.02 14.4 0.0 3.5 7.1 0.0 2.2 2 0 0 2 2 2 0 MraW methylase family COesterase PF00135.28 EPE28830.1 - 0.0002 20.4 0.0 0.0021 17.0 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 EPE28831.1 - 7.2e-44 150.5 0.0 8.5e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE28831.1 - 0.19 11.6 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold ketoacyl-synt PF00109.26 EPE28832.1 - 5.3e-74 249.0 0.6 7.1e-73 245.3 0.1 3.1 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EPE28832.1 - 1.7e-32 111.9 0.2 3.7e-32 110.8 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 EPE28832.1 - 2.2e-27 94.7 0.0 1e-26 92.6 0.0 2.2 2 0 0 2 2 1 1 Helix-turn-helix domain Acyl_transf_1 PF00698.21 EPE28832.1 - 3.1e-22 79.5 1.0 1.4e-21 77.4 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.6 EPE28832.1 - 2.4e-20 73.0 0.0 3.7e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EPE28832.1 - 1.4e-13 51.4 0.0 3.9e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.13 EPE28832.1 - 6.5e-13 49.0 0.0 1.5e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_23 PF13489.6 EPE28832.1 - 1.1e-11 44.9 0.0 1.5e-10 41.2 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain SAT PF16073.5 EPE28832.1 - 3e-10 40.2 9.7 1e-09 38.5 0.1 3.2 3 1 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis KAsynt_C_assoc PF16197.5 EPE28832.1 - 7.3e-10 39.3 0.0 5.3e-09 36.5 0.0 2.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EPE28832.1 - 9.8e-09 35.5 4.8 1e-08 35.4 2.7 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 EPE28832.1 - 3.4e-08 34.1 0.0 1.3e-07 32.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.21 EPE28832.1 - 2.7e-07 30.3 0.5 0.0012 18.3 0.0 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase family Methyltransf_31 PF13847.6 EPE28832.1 - 6.6e-06 26.0 0.0 2e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE28832.1 - 3.7e-05 24.3 0.0 0.0002 21.9 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.7 EPE28832.1 - 4.5e-05 24.2 1.4 4.5e-05 24.2 1.4 3.3 3 1 0 3 3 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 EPE28832.1 - 9.4e-05 21.9 0.1 0.00018 21.0 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain DLH PF01738.18 EPE28832.1 - 0.00034 20.2 0.0 1.8 8.1 0.0 3.5 3 0 0 3 3 3 2 Dienelactone hydrolase family Ubie_methyltran PF01209.18 EPE28832.1 - 0.015 14.7 0.0 0.04 13.2 0.0 1.7 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Hydrolase_4 PF12146.8 EPE28832.1 - 0.023 14.0 0.0 0.26 10.5 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ACP_syn_III PF08545.10 EPE28832.1 - 0.03 14.2 1.5 0.11 12.4 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF829 PF05705.14 EPE28832.1 - 0.038 13.9 0.0 0.46 10.3 0.0 2.7 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF829) COesterase PF00135.28 EPE28832.1 - 0.043 12.7 0.0 0.098 11.5 0.0 1.5 1 0 0 1 1 1 0 Carboxylesterase family Thioesterase PF00975.20 EPE28832.1 - 0.18 11.9 0.3 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain MtrF PF09472.10 EPE28832.1 - 0.2 11.1 2.6 0.97 8.9 0.1 2.9 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) p450 PF00067.22 EPE28833.1 - 1.6e-40 139.3 0.0 3e-40 138.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 SeqA PF03925.13 EPE28833.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 SeqA protein C-terminal domain CDC37_N PF03234.14 EPE28833.1 - 0.066 14.1 0.0 0.15 13.0 0.0 1.5 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Transformer PF06495.11 EPE28834.1 - 0.019 15.1 1.7 0.037 14.1 1.7 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein KIAA1430 PF13879.6 EPE28834.1 - 0.032 15.0 0.6 0.21 12.4 0.1 2.3 2 0 0 2 2 2 0 KIAA1430 homologue FSH1 PF03959.13 EPE28835.1 - 6e-29 101.2 0.0 8.1e-29 100.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EPE28835.1 - 1.3e-05 25.1 0.0 0.002 18.0 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Isochorismatase PF00857.20 EPE28837.1 - 3e-42 144.8 0.0 3.7e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Abhydrolase_6 PF12697.7 EPE28838.1 - 2.7e-08 34.7 0.1 3.4e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_31 PF13847.6 EPE28840.1 - 0.00042 20.1 0.0 0.00087 19.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE28840.1 - 0.00045 20.9 0.0 0.00077 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE28840.1 - 0.00074 19.4 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Fe-ADH_2 PF13685.6 EPE28840.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase DUF3328 PF11807.8 EPE28841.1 - 1.3e-18 67.6 0.6 1.9e-18 67.1 0.6 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) SCA7 PF08313.12 EPE28842.1 - 2.6e-28 97.7 0.9 2.6e-28 97.7 0.9 2.1 2 0 0 2 2 2 1 SCA7, zinc-binding domain CDC45 PF02724.14 EPE28842.1 - 0.25 9.6 12.6 0.31 9.3 12.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3774 PF12609.8 EPE28842.1 - 1.8 9.6 0.0 1.8 9.6 0.0 3.3 3 0 0 3 3 3 0 Wound-induced protein p450 PF00067.22 EPE28843.1 - 3.6e-50 171.1 0.0 4.5e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Actin PF00022.19 EPE28844.1 - 4.7e-101 338.4 0.0 2.9e-100 335.8 0.0 1.8 1 1 0 1 1 1 1 Actin GCIP PF13324.6 EPE28845.1 - 3.3e-28 99.0 1.1 4.5e-28 98.6 0.0 1.6 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting Amino_oxidase PF01593.24 EPE28846.1 - 1.6e-37 129.9 0.2 4.3e-37 128.5 0.2 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPE28846.1 - 1.8e-11 44.1 0.0 4.8e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE28846.1 - 0.013 14.7 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE28846.1 - 0.046 14.3 0.2 0.36 11.4 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE28846.1 - 0.12 11.6 0.2 0.35 10.1 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EPE28846.1 - 0.25 10.6 1.1 0.62 9.3 0.4 2.1 2 0 0 2 2 2 0 FAD binding domain Pec_lyase_C PF00544.19 EPE28848.1 - 1.2e-21 77.3 7.3 9.7e-21 74.3 7.3 2.0 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EPE28848.1 - 4.5e-07 29.8 13.9 1.8e-05 24.6 11.7 2.2 1 1 0 1 1 1 1 Right handed beta helix region DUF4957 PF16318.5 EPE28848.1 - 0.098 12.6 1.3 0.19 11.6 0.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4957) Sugar_tr PF00083.24 EPE28849.1 - 9.8e-92 308.2 22.1 1.2e-91 307.9 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE28849.1 - 3.9e-30 105.0 28.5 1e-22 80.5 5.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Polysacc_deac_1 PF01522.21 EPE28850.1 - 2e-27 95.6 0.0 2.8e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EPE28850.1 - 0.065 12.4 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 UFD1 PF03152.14 EPE28851.1 - 2.1e-26 92.4 0.0 3.3e-21 75.5 0.0 3.4 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 EPE28851.1 - 1.7e-06 28.2 1.8 4.6e-06 26.8 0.1 2.6 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DUF2442 PF10387.9 EPE28851.1 - 0.07 13.4 0.0 5.6 7.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2442) Glyco_hydro_17 PF00332.18 EPE28853.1 - 1.3e-22 80.8 0.6 1.7e-22 80.5 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 TORC_M PF12885.7 EPE28853.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain fn3_3 PF14686.6 EPE28854.1 - 1.8e-28 98.1 0.3 4.9e-28 96.7 0.3 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 EPE28854.1 - 7.2e-27 94.3 2.1 1.2e-26 93.6 0.1 2.2 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.6 EPE28854.1 - 0.0071 16.6 0.1 0.021 15.1 0.1 1.8 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Bac_surface_Ag PF01103.23 EPE28855.1 - 1.2e-43 149.9 2.0 1.5e-43 149.6 2.0 1.1 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.26 EPE28856.1 - 3.4e-18 65.7 0.1 4.7e-18 65.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPE28856.1 - 0.091 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B MARVEL PF01284.23 EPE28858.1 - 7.2e-22 78.0 17.4 8.5e-22 77.7 17.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain LPD34 PF18852.1 EPE28859.1 - 0.00041 20.0 0.2 0.00086 19.0 0.1 1.5 1 1 0 1 1 1 1 Large polyvalent protein associated domain 34 DUF2639 PF11121.8 EPE28859.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2639) DSPc PF00782.20 EPE28860.1 - 1.4e-23 83.2 0.0 1.7e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EPE28860.1 - 5.4e-05 22.9 0.0 6.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EPE28860.1 - 0.0023 18.2 0.4 0.021 15.1 0.2 2.2 2 1 0 2 2 2 1 Rit1 DUSP-like domain RL PF17797.1 EPE28860.1 - 0.015 15.2 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 RL domain PTPlike_phytase PF14566.6 EPE28860.1 - 0.045 13.9 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Sugar_tr PF00083.24 EPE28861.1 - 1.8e-30 106.2 23.9 2.1e-29 102.7 23.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE28861.1 - 7.3e-27 94.2 31.1 6.9e-23 81.1 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HRI1 PF16815.5 EPE28864.1 - 2.2e-64 217.3 1.8 2.5e-64 217.1 1.8 1.0 1 0 0 1 1 1 1 Protein HRI1 Cyto_heme_lyase PF01265.17 EPE28865.1 - 8.7e-120 399.7 1.1 9.8e-120 399.5 1.1 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ABC1 PF03109.16 EPE28866.1 - 1e-21 77.3 0.0 5.7e-12 45.8 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 EPE28866.1 - 0.026 14.4 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EPE28866.1 - 0.11 12.0 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family YrzO PF14142.6 EPE28866.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 YrzO-like protein AA_permease_2 PF13520.6 EPE28870.1 - 4.8e-70 236.5 35.3 6.5e-70 236.1 35.3 1.1 1 0 0 1 1 1 1 Amino acid permease TauD PF02668.16 EPE28871.1 - 9e-32 110.9 0.1 1.4e-31 110.3 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EPE28871.1 - 0.034 13.3 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 CsiD CRC_subunit PF08624.10 EPE28875.1 - 3.7e-34 118.1 0.1 6.5e-34 117.3 0.1 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Spermine_synth PF01564.17 EPE28876.1 - 8.3e-07 28.6 0.0 2.6e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Spermine/spermidine synthase domain MR_MLE_C PF13378.6 EPE28877.1 - 4.4e-57 193.2 0.0 6.2e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EPE28877.1 - 0.00043 20.5 0.3 0.0017 18.6 0.0 2.0 3 0 0 3 3 3 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 EPE28877.1 - 0.015 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus DAO PF01266.24 EPE28879.1 - 3.9e-30 105.6 3.2 6e-30 105.0 3.2 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE28879.1 - 9.4e-05 22.6 1.5 0.00012 22.2 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE28879.1 - 0.00067 19.0 0.6 0.0065 15.7 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE28879.1 - 0.001 18.3 0.0 0.0024 17.0 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EPE28879.1 - 0.0024 17.2 0.1 0.0044 16.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EPE28879.1 - 0.039 13.2 0.0 0.44 9.8 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 EPE28879.1 - 0.056 14.0 2.2 0.2 12.3 0.2 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPE28879.1 - 0.11 12.5 0.1 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 EPE28879.1 - 0.21 11.3 0.6 0.38 10.4 0.6 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NDT80_PhoG PF05224.12 EPE28880.1 - 2.3e-32 112.7 0.0 9.9e-32 110.7 0.0 2.0 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Hexokinase_2 PF03727.16 EPE28881.1 - 4e-56 190.1 0.0 6e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EPE28881.1 - 1.7e-43 148.9 0.0 2.5e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Glucosamine_iso PF01182.20 EPE28882.1 - 7.8e-22 78.3 0.0 1.2e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Peroxidase_2 PF01328.17 EPE28884.1 - 1.2e-41 143.3 0.0 1.6e-41 142.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Glyco_hydro_3 PF00933.21 EPE28885.1 - 3.4e-64 217.2 0.0 4.5e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EPE28885.1 - 0.00073 19.5 0.1 0.0021 18.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.25 EPE28885.1 - 0.00094 19.4 0.0 0.0037 17.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE28885.1 - 0.023 14.7 0.0 0.068 13.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE28885.1 - 0.17 12.4 0.0 0.55 10.7 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidohydro_1 PF01979.20 EPE28886.1 - 2.8e-14 53.2 0.0 5e-14 52.4 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPE28886.1 - 5.5e-08 32.7 0.0 1.5e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Amidohydrolase family F-box-like PF12937.7 EPE28887.1 - 5.5e-08 32.6 0.9 8.8e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EPE28887.1 - 0.038 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 F-box domain Fungal_trans PF04082.18 EPE28888.1 - 4.9e-09 35.6 0.7 8e-09 34.9 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE28888.1 - 2.8e-08 33.7 10.7 5.7e-08 32.8 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aspzincin_M35 PF14521.6 EPE28892.1 - 4.4e-06 27.3 0.1 1e-05 26.1 0.1 1.6 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase APH PF01636.23 EPE28893.1 - 3e-12 47.0 0.0 9.5e-12 45.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EPE28893.1 - 0.0019 17.6 0.1 0.0029 17.0 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EPE28893.1 - 0.0081 15.1 0.0 0.016 14.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1679) RIO1 PF01163.22 EPE28893.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Glyco_hydro_16 PF00722.21 EPE28895.1 - 5e-37 127.1 0.8 5e-37 127.1 0.8 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Pox_T4_C PF04490.12 EPE28895.1 - 0.064 13.4 0.6 0.098 12.8 0.6 1.2 1 0 0 1 1 1 0 Poxvirus T4 protein, C terminus WD40 PF00400.32 EPE28897.1 - 2.7e-21 75.5 22.9 0.0001 23.0 0.1 7.0 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE28897.1 - 6.6e-12 45.6 4.0 1.5e-05 25.2 0.0 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 EPE28897.1 - 0.00011 22.2 8.4 0.024 14.5 0.7 3.3 1 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 EPE28897.1 - 0.014 14.4 0.2 4.2 6.2 0.0 3.7 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein JHY PF15261.6 EPE28898.1 - 2 9.1 6.7 1.2 9.9 0.7 2.3 1 1 1 2 2 2 0 Jhy protein SAD_SRA PF02182.17 EPE28899.1 - 5.7e-38 130.1 0.1 8.3e-38 129.6 0.1 1.2 1 0 0 1 1 1 1 SAD/SRA domain Dscam_C PF12355.8 EPE28899.1 - 4.9 8.1 7.5 0.48 11.4 0.7 2.4 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal ABC2_membrane PF01061.24 EPE28900.1 - 7.9e-78 260.7 56.0 3e-40 137.9 24.3 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EPE28900.1 - 7.5e-36 123.7 0.0 5.3e-18 65.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EPE28900.1 - 1.8e-26 91.9 6.3 1e-23 83.0 0.0 3.6 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EPE28900.1 - 1.1e-15 58.0 0.4 5e-15 55.9 0.3 2.3 3 0 0 3 3 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 EPE28900.1 - 1.7e-07 31.3 0.0 0.014 15.2 0.0 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EPE28900.1 - 5.2e-06 27.0 0.1 0.0048 17.3 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EPE28900.1 - 1.1e-05 25.6 0.1 0.0037 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EPE28900.1 - 4.4e-05 23.8 1.1 0.079 13.2 0.1 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EPE28900.1 - 6.2e-05 23.6 0.0 0.0062 17.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EPE28900.1 - 0.00014 21.5 0.2 0.003 17.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EPE28900.1 - 0.00017 21.3 0.2 0.0097 15.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.6 EPE28900.1 - 0.00024 21.6 0.0 0.016 15.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EPE28900.1 - 0.00063 18.9 43.9 0.0054 15.9 22.3 3.5 2 1 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EPE28900.1 - 0.0011 18.9 0.5 0.0049 16.8 0.0 2.3 3 0 0 3 3 2 1 RsgA GTPase SMC_N PF02463.19 EPE28900.1 - 0.002 17.6 0.0 0.3 10.5 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EPE28900.1 - 0.003 17.3 0.1 0.73 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 EPE28900.1 - 0.03 13.0 0.6 6.8 5.2 0.0 3.2 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 EPE28900.1 - 0.036 14.0 0.4 6.6 6.6 0.1 2.4 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 EPE28900.1 - 0.038 13.6 1.8 0.27 10.8 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EPE28900.1 - 0.041 14.2 0.9 0.71 10.1 0.1 2.8 2 1 0 2 2 2 0 AAA domain DnaB_C PF03796.15 EPE28900.1 - 0.053 12.8 0.0 2.1 7.6 0.0 2.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain FtsK_SpoIIIE PF01580.18 EPE28900.1 - 0.057 12.8 2.1 13 5.0 0.1 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family PduV-EutP PF10662.9 EPE28900.1 - 0.12 12.1 0.2 11 5.7 0.1 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 EPE28900.1 - 0.13 12.7 0.1 18 5.8 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EPE28900.1 - 0.14 12.6 0.4 0.52 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EPE28900.1 - 0.56 10.5 1.8 18 5.6 0.1 2.9 3 0 0 3 3 2 0 AAA domain Spherulin4 PF12138.8 EPE28901.1 - 2.7e-54 184.4 6.5 3.2e-54 184.1 6.5 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 ORC_WH_C PF18137.1 EPE28901.1 - 0.043 13.9 2.2 0.063 13.3 2.2 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Mpp10 PF04006.12 EPE28901.1 - 0.055 11.9 15.7 0.063 11.7 15.7 1.1 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 EPE28901.1 - 0.18 11.2 14.1 0.24 10.8 14.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 EPE28901.1 - 0.55 8.4 20.7 0.68 8.1 20.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EPE28901.1 - 1.4 7.1 15.8 1.8 6.7 15.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EPE28901.1 - 3.2 7.1 20.6 4.1 6.7 20.6 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 EPE28901.1 - 5.3 6.3 25.6 8.8 5.5 25.6 1.4 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 EPE28901.1 - 7.1 6.1 17.8 11 5.5 17.8 1.3 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 EPE28901.1 - 7.8 6.4 19.5 11 5.9 19.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.9 EPE28901.1 - 8.7 5.4 26.7 11 5.0 26.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Melibiase_2 PF16499.5 EPE28902.1 - 3.6e-55 187.1 0.2 6.9e-55 186.2 0.2 1.5 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EPE28902.1 - 1.5e-14 53.8 1.3 4.8e-14 52.2 0.2 2.4 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Ricin_B_lectin PF00652.22 EPE28902.1 - 9.7e-12 45.2 2.5 1.7e-11 44.5 2.5 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 EPE28902.1 - 0.0035 16.9 0.2 0.0078 15.8 0.2 1.5 1 0 0 1 1 1 1 Cytolethal distending toxin A/C domain PhyH PF05721.13 EPE28903.1 - 1.2e-09 38.8 0.0 3.2e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Epimerase PF01370.21 EPE28904.1 - 1.9e-13 50.4 0.0 6.5e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPE28904.1 - 1.3e-09 38.2 0.2 2.6e-09 37.3 0.2 1.6 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EPE28904.1 - 1.9e-07 30.4 0.0 4.9e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EPE28904.1 - 1.4e-05 24.8 0.2 0.00039 20.0 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family TrkA_N PF02254.18 EPE28904.1 - 3.8e-05 23.9 0.4 5.8e-05 23.3 0.4 1.2 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 EPE28904.1 - 0.00013 21.4 0.2 0.0014 18.2 0.4 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.24 EPE28904.1 - 0.0005 20.5 0.1 0.0008 19.8 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EPE28904.1 - 0.00071 20.1 0.2 0.0015 19.1 0.2 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 EPE28904.1 - 0.00075 18.7 0.1 0.0013 17.9 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 EPE28904.1 - 0.0017 18.3 0.1 0.045 13.7 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_4 PF07993.12 EPE28904.1 - 0.0024 17.1 0.0 0.38 9.9 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 EPE28904.1 - 0.0028 17.6 0.2 0.0059 16.5 0.2 1.5 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EPE28904.1 - 0.0068 15.5 0.0 2.6 7.1 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain Shikimate_DH PF01488.20 EPE28904.1 - 0.011 15.8 0.2 0.019 15.0 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 EPE28904.1 - 0.02 15.0 0.1 0.046 13.8 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 EPE28904.1 - 0.025 14.0 0.0 0.58 9.5 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase CbiJ PF02571.14 EPE28904.1 - 0.057 12.9 0.2 0.082 12.4 0.2 1.3 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK NAD_binding_3 PF03447.16 EPE28904.1 - 0.11 13.2 0.1 0.28 11.9 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Glyco_hydro_125 PF06824.11 EPE28907.1 - 3.5e-183 609.2 0.1 4.3e-183 608.9 0.1 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Glyco_hydro_100 PF12899.7 EPE28907.1 - 0.12 11.0 0.0 0.29 9.8 0.0 1.5 2 0 0 2 2 2 0 Alkaline and neutral invertase Nuc_deoxyri_tr2 PF15891.5 EPE28909.1 - 5.5e-32 110.3 0.0 7e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like Nuc_deoxyrib_tr PF05014.15 EPE28909.1 - 2.9e-05 24.1 0.0 3.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase MCPVI PF02993.14 EPE28911.1 - 0.2 11.4 0.3 0.32 10.8 0.3 1.2 1 0 0 1 1 1 0 Minor capsid protein VI UvrD-helicase PF00580.21 EPE28912.1 - 4.3e-60 203.9 3.3 1.4e-58 198.9 0.3 2.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EPE28912.1 - 6.2e-59 200.1 0.0 1.1e-58 199.3 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EPE28912.1 - 1.1e-30 106.8 0.2 8.8e-30 104.0 0.0 2.6 3 1 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.6 EPE28912.1 - 1.3e-14 53.7 0.0 7.1e-14 51.4 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EPE28912.1 - 1e-08 35.1 0.1 2.5e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EPE28912.1 - 1.6e-05 24.7 0.3 0.066 12.9 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 EPE28912.1 - 0.0022 17.7 0.3 0.0071 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPE28912.1 - 0.098 12.9 0.2 22 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain DIOX_N PF14226.6 EPE28913.1 - 7.6e-33 113.8 0.0 1e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPE28913.1 - 4.2e-25 88.2 0.0 7e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungus-induced PF10917.8 EPE28913.1 - 0.056 13.8 0.3 0.12 12.7 0.3 1.6 1 0 0 1 1 1 0 Fungus-induced protein zf_C2H2_6 PF18450.1 EPE28915.1 - 0.33 10.7 1.1 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Zinc Finger domain ABC_tran PF00005.27 EPE28916.1 - 1.7e-47 161.4 0.9 4.4e-23 82.3 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EPE28916.1 - 6.4e-20 71.0 7.5 6.4e-20 71.0 7.5 3.2 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 EPE28916.1 - 3.5e-16 59.9 0.1 0.0038 17.1 0.0 4.6 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPE28916.1 - 1.3e-11 44.4 0.4 0.0084 15.6 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EPE28916.1 - 5.1e-06 26.6 0.1 0.082 13.0 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EPE28916.1 - 5.6e-06 26.0 0.3 0.14 11.9 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EPE28916.1 - 1.2e-05 25.3 0.5 0.093 12.6 0.0 2.8 2 1 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 EPE28916.1 - 2e-05 24.9 0.0 0.26 11.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EPE28916.1 - 2.6e-05 24.8 19.2 0.0049 17.4 0.1 4.7 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.6 EPE28916.1 - 3.1e-05 24.4 0.3 0.048 14.0 0.2 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EPE28916.1 - 3.3e-05 24.4 0.0 0.53 10.8 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 EPE28916.1 - 4.1e-05 23.4 0.7 0.46 10.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EPE28916.1 - 7e-05 23.0 0.1 0.6 10.3 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 EPE28916.1 - 9.3e-05 22.9 0.1 0.52 10.7 0.1 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EPE28916.1 - 0.00011 22.2 0.2 1 9.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 EPE28916.1 - 0.00034 20.6 0.0 0.35 10.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 EPE28916.1 - 0.00042 20.1 0.1 0.11 12.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EPE28916.1 - 0.002 18.5 0.0 3.2 8.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 EPE28916.1 - 0.0049 17.1 5.2 0.24 11.6 0.0 3.1 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 EPE28916.1 - 0.0089 16.0 0.0 0.9 9.4 0.0 2.7 2 0 0 2 2 2 1 NTPase cobW PF02492.19 EPE28916.1 - 0.011 15.3 0.7 1.7 8.2 0.6 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EPE28916.1 - 0.012 15.8 0.1 9 6.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 EPE28916.1 - 0.013 15.3 17.4 0.087 12.5 0.0 4.6 4 1 1 5 5 5 0 AAA ATPase domain TsaE PF02367.17 EPE28916.1 - 0.016 15.2 0.0 3.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 EPE28916.1 - 0.018 14.9 0.4 0.64 9.9 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 EPE28916.1 - 0.02 14.9 0.3 6.3 6.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EPE28916.1 - 0.022 14.0 0.1 4.4 6.4 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 EPE28916.1 - 0.034 13.4 1.8 4.7 6.4 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin SRP54 PF00448.22 EPE28916.1 - 0.036 13.7 0.2 5.4 6.6 0.1 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MeaB PF03308.16 EPE28916.1 - 0.038 13.0 2.0 5.3 5.9 0.0 2.6 3 0 0 3 3 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 EPE28916.1 - 0.043 13.3 0.0 3.8 7.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 EPE28916.1 - 0.049 13.3 0.1 2 8.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 EPE28916.1 - 0.17 12.3 3.9 31 5.0 0.3 3.8 3 0 0 3 3 3 0 AAA domain Adeno_IVa2 PF02456.15 EPE28916.1 - 0.19 10.5 0.1 10 4.8 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein Dynamin_N PF00350.23 EPE28916.1 - 0.35 10.9 8.1 3.5 7.6 0.1 3.9 4 1 0 4 4 4 0 Dynamin family AAA_27 PF13514.6 EPE28916.1 - 1.2 8.6 7.5 5.7 6.5 0.0 3.6 5 0 0 5 5 2 0 AAA domain ATPase_2 PF01637.18 EPE28916.1 - 2 8.2 6.8 30 4.4 0.0 3.9 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea TMF_TATA_bd PF12325.8 EPE28916.1 - 9.6 6.5 18.1 0.87 9.8 3.5 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Tubulin PF00091.25 EPE28917.1 - 2.4e-68 230.2 0.1 4.5e-68 229.4 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EPE28917.1 - 2.7e-42 143.9 0.1 4.4e-42 143.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EPE28917.1 - 4.8e-05 23.7 0.0 0.00013 22.2 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EPE28917.1 - 0.0022 17.3 0.0 0.024 13.8 0.0 2.0 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 EPE28917.1 - 0.0037 17.0 0.0 0.0071 16.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Arginosuc_synth PF00764.19 EPE28918.1 - 1.2e-155 518.6 0.0 1.4e-155 518.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EPE28918.1 - 0.0041 16.6 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EPE28918.1 - 0.027 13.3 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase CIA30 PF08547.12 EPE28919.1 - 4.3e-40 137.3 0.1 4.9e-40 137.2 0.1 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) bZIP_1 PF00170.21 EPE28920.1 - 0.0039 17.3 8.8 0.007 16.4 8.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPE28920.1 - 0.0074 16.3 7.0 0.012 15.7 7.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EPE28920.1 - 0.055 14.0 4.4 0.11 13.1 4.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Na_H_Exchanger PF00999.21 EPE28922.1 - 3.3e-61 207.2 44.0 4.5e-61 206.7 44.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family bZIP_1 PF00170.21 EPE28925.1 - 1.9e-07 31.0 2.3 3.1e-07 30.4 2.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPE28925.1 - 1.8e-06 27.9 6.9 3e-06 27.2 6.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper DUF1773 PF08593.10 EPE28925.1 - 0.62 11.1 2.8 25 6.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function SGL PF08450.12 EPE28926.1 - 0.00038 20.1 0.1 0.098 12.2 0.0 2.5 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 EPE28926.1 - 0.0016 17.8 0.1 0.13 11.5 0.0 2.9 2 1 1 3 3 3 1 Lactonase, 7-bladed beta-propeller Reg_prop PF07494.11 EPE28926.1 - 0.11 12.8 0.1 5.3 7.6 0.0 3.2 2 1 1 3 3 3 0 Two component regulator propeller EF-hand_14 PF17959.1 EPE28927.1 - 0.19 12.1 0.0 0.42 11.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain MAP17 PF15807.5 EPE28929.1 - 0.021 15.0 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PKS_DE PF18369.1 EPE28929.1 - 0.13 12.8 0.9 17 6.1 0.1 2.6 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain Plug PF07715.15 EPE28930.1 - 0.033 14.7 0.1 0.051 14.1 0.1 1.2 1 0 0 1 1 1 0 TonB-dependent Receptor Plug Domain Antimicrobial_2 PF08023.12 EPE28932.1 - 2.5 8.7 5.7 1.6e+02 3.0 0.1 4.1 4 0 0 4 4 4 0 Frog antimicrobial peptide CagE_TrbE_VirB PF03135.14 EPE28935.1 - 0.0092 16.1 0.5 0.015 15.4 0.5 1.3 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system MutS_III PF05192.18 EPE28936.1 - 0.12 12.6 0.4 0.17 12.1 0.4 1.2 1 0 0 1 1 1 0 MutS domain III Amdase PF17645.1 EPE28937.1 - 1.1e-14 54.6 0.0 1.4e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Arylmalonate decarboxylase Asp_Glu_race PF01177.22 EPE28937.1 - 3e-07 30.5 0.0 3.8e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase LMF1 PF06762.14 EPE28938.1 - 0.089 11.9 0.2 0.11 11.6 0.2 1.0 1 0 0 1 1 1 0 Lipase maturation factor EBP50_C PF09007.11 EPE28938.1 - 0.28 12.2 5.7 0.35 11.8 5.7 1.0 1 0 0 1 1 1 0 EBP50, C-terminal T4_Gp59_C PF08994.10 EPE28939.1 - 0.055 14.1 0.0 0.074 13.7 0.0 1.2 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term GMC_oxred_N PF00732.19 EPE28940.1 - 1.9e-54 185.1 0.0 2.4e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE28940.1 - 5.5e-34 117.7 0.0 1.1e-33 116.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EPE28940.1 - 0.00013 21.2 0.1 0.00021 20.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EPE28940.1 - 0.00094 18.9 9.6 0.0096 15.5 3.9 3.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE28940.1 - 0.00095 18.5 0.0 0.09 12.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE28940.1 - 0.0028 17.8 0.1 0.0095 16.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EPE28940.1 - 0.0066 15.2 0.3 1.2 7.8 0.0 2.6 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_3 PF13738.6 EPE28940.1 - 0.038 13.2 0.0 5.9 6.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPE28940.1 - 0.042 13.8 1.3 0.18 11.8 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 EPE28940.1 - 0.063 12.5 0.3 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Thi4 family TfuA PF07812.12 EPE28940.1 - 0.15 11.8 0.1 0.44 10.3 0.1 1.7 1 0 0 1 1 1 0 TfuA-like protein AA_permease PF00324.21 EPE28941.1 - 1.4e-111 373.5 30.9 1.7e-111 373.2 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE28941.1 - 5.1e-20 71.7 35.3 7.1e-20 71.2 35.3 1.1 1 0 0 1 1 1 1 Amino acid permease Orthoreo_P10 PF07204.11 EPE28941.1 - 0.29 11.1 1.4 0.86 9.6 1.4 1.9 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF1989 PF09347.10 EPE28944.1 - 1.1e-60 204.1 0.0 1.4e-60 203.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) AA_permease PF00324.21 EPE28945.1 - 1.6e-110 370.0 50.1 1.9e-110 369.7 50.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE28945.1 - 3.8e-22 78.7 55.3 4.7e-22 78.4 55.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2252 PF10009.9 EPE28946.1 - 0.23 10.5 6.2 0.36 9.9 6.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Glyco_hydro_61 PF03443.14 EPE28947.1 - 7.2e-36 124.1 0.1 8.8e-36 123.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 UPF0029 PF01205.19 EPE28948.1 - 3.4e-30 104.5 0.0 6.2e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 ECH_2 PF16113.5 EPE28948.1 - 0.029 13.9 0.3 0.049 13.1 0.3 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Aim21 PF11489.8 EPE28949.1 - 3.9e-207 690.6 70.7 3.9e-207 690.6 70.7 2.5 3 0 0 3 3 3 1 Altered inheritance of mitochondria protein 21 Cg6151-P PF10233.9 EPE28950.1 - 1e-40 138.5 12.5 1.2e-40 138.3 12.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF2721 PF11026.8 EPE28950.1 - 6.8 6.6 11.9 2 8.3 5.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Not1 PF04054.15 EPE28951.1 - 3.8e-137 457.1 1.3 7e-137 456.2 1.3 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EPE28951.1 - 2.1e-85 285.7 3.9 5.7e-85 284.3 3.9 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 EPE28951.1 - 1.9e-47 160.9 6.1 1.9e-47 160.9 6.1 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EPE28951.1 - 2.8e-47 160.4 0.1 2.1e-45 154.2 0.0 3.4 4 0 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EPE28951.1 - 1.3e-35 122.7 1.3 2.7e-35 121.6 0.1 2.2 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat ADH_zinc_N PF00107.26 EPE28953.1 - 1.6e-13 50.7 0.2 2.6e-13 50.1 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE28953.1 - 2.2e-07 30.7 0.0 5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EPE28953.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EPE28953.1 - 0.099 13.7 0.2 0.23 12.5 0.2 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase FCH PF00611.23 EPE28954.1 - 2.6e-17 62.9 0.2 8.5e-17 61.2 0.2 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EPE28954.1 - 1.4e-12 47.0 0.0 2.7e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPE28954.1 - 8.2e-12 44.8 0.0 1.5e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EPE28954.1 - 4.1e-10 39.2 0.0 1.1e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Seipin PF06775.14 EPE28955.1 - 5.5e-60 202.8 1.5 7.1e-60 202.5 1.5 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Pkinase PF00069.25 EPE28956.1 - 5.9e-69 232.4 0.0 1.2e-68 231.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE28956.1 - 6.2e-39 133.8 0.1 5.7e-38 130.7 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EPE28956.1 - 9.5e-20 70.1 0.1 1.8e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 EPE28956.1 - 7.4e-06 25.5 0.1 1.3e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EPE28956.1 - 5.5e-05 22.3 0.0 9.7e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EPE28956.1 - 0.00014 21.2 0.0 0.00028 20.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPE28956.1 - 0.0013 18.7 0.2 0.016 15.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 EPE28956.1 - 0.0082 15.8 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.22 EPE28956.1 - 0.083 12.5 0.3 0.27 10.8 0.3 1.8 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 EPE28956.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1604 PF07713.13 EPE28957.1 - 1.7e-39 133.5 2.0 1.7e-39 133.5 2.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EPE28957.1 - 9e-09 35.1 1.4 7e-08 32.2 0.5 2.7 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EPE28957.1 - 0.002 18.1 0.5 0.002 18.1 0.5 3.7 3 1 1 4 4 4 1 G-patch domain ADH_zinc_N PF00107.26 EPE28958.1 - 4e-10 39.8 0.0 7.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE28958.1 - 1.7e-09 37.5 0.0 8.1e-09 35.3 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TBP PF00352.21 EPE28959.1 - 1.9e-67 223.2 0.1 9.2e-33 112.1 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EPE28959.1 - 0.00011 22.2 0.0 0.22 11.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EPE28959.1 - 0.12 12.2 0.1 0.68 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) DAO PF01266.24 EPE28960.1 - 2.5e-43 149.0 0.0 2.9e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE28960.1 - 8.7e-06 25.2 0.0 0.057 12.6 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EPE28960.1 - 2.7e-05 23.5 0.0 0.00016 20.9 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EPE28960.1 - 3.5e-05 23.8 0.0 0.012 15.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EPE28960.1 - 6.4e-05 23.1 0.0 0.00014 22.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EPE28960.1 - 0.0045 16.2 0.0 0.008 15.4 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EPE28960.1 - 0.013 14.7 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 EPE28960.1 - 0.018 15.3 0.0 0.047 13.9 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Trp_halogenase PF04820.14 EPE28960.1 - 0.037 12.9 0.0 4.3 6.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 EPE28960.1 - 0.066 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EPE28960.1 - 0.19 12.3 0.0 3 8.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Surp PF01805.20 EPE28961.1 - 4.5e-10 39.4 0.0 1.3e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Surp module Flot PF15975.5 EPE28961.1 - 0.2 11.9 0.6 9.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Flotillin Pkinase PF00069.25 EPE28962.1 - 8e-19 68.0 0.0 1e-14 54.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE28962.1 - 0.00024 20.5 0.1 0.0008 18.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase DCB PF16213.5 EPE28963.1 - 5.6e-44 149.9 2.0 5.6e-44 149.9 2.0 3.2 3 1 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EPE28963.1 - 8.2e-43 146.0 0.2 8.2e-43 146.0 0.2 3.4 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 EPE28963.1 - 1.5e-23 82.9 13.9 3.5e-21 75.1 1.4 4.6 4 1 0 4 4 4 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 EPE28963.1 - 0.0035 17.2 0.0 0.14 12.0 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) STAS_2 PF13466.6 EPE28963.1 - 0.24 11.8 8.5 1.4 9.3 0.1 4.3 4 0 0 4 4 4 0 STAS domain UQ_con PF00179.26 EPE28964.1 - 4.2e-10 39.4 0.1 3.8e-08 33.1 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Complex1_LYR PF05347.15 EPE28965.1 - 0.00019 21.4 0.0 0.00065 19.7 0.0 1.9 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HSP70 PF00012.20 EPE28966.1 - 3.7e-07 28.7 3.8 5.9e-07 28.1 0.4 2.0 2 0 0 2 2 2 2 Hsp70 protein POTRA_TamA_1 PF17243.2 EPE28966.1 - 0.89 9.7 2.5 13 5.9 0.3 2.3 2 0 0 2 2 2 0 POTRA domain TamA domain 1 bZIP_1 PF00170.21 EPE28967.1 - 2.7e-06 27.4 0.8 2.7e-06 27.4 0.8 1.9 2 0 0 2 2 2 1 bZIP transcription factor Rcd1 PF04078.13 EPE28968.1 - 2e-125 417.3 4.9 2.4e-125 417.1 4.9 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like baeRF_family10 PF18854.1 EPE28968.1 - 0.033 14.4 3.1 0.91 9.8 0.8 2.5 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 NSP2-B_epitope PF14757.6 EPE28968.1 - 0.072 12.8 1.0 0.14 11.8 1.0 1.4 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein OSCP PF00213.18 EPE28968.1 - 0.75 9.9 5.3 0.92 9.6 0.0 2.6 2 1 0 2 2 2 0 ATP synthase delta (OSCP) subunit BTB PF00651.31 EPE28969.1 - 1.1e-06 28.8 0.0 2.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EPE28970.1 - 3.5e-10 40.1 0.0 4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain SnoaL PF07366.12 EPE28970.1 - 0.052 13.4 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase PI3K_rbd PF00794.18 EPE28970.1 - 0.1 12.7 0.0 0.15 12.2 0.0 1.3 1 1 0 1 1 1 0 PI3-kinase family, ras-binding domain F-box-like PF12937.7 EPE28971.1 - 7.3e-05 22.6 0.1 0.00021 21.1 0.1 1.8 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EPE28971.1 - 1.2 9.7 6.9 18 5.9 0.3 4.8 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Glyco_transf_15 PF01793.16 EPE28972.1 - 2.6e-79 266.9 8.9 2e-51 175.2 6.5 2.1 1 1 1 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Hira PF07569.11 EPE28973.1 - 3.1e-87 292.0 0.2 7.2e-87 290.8 0.0 1.7 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 EPE28973.1 - 8.8e-25 86.5 31.2 1.7e-05 25.5 0.2 9.3 8 1 1 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE28973.1 - 2e-14 53.6 0.0 0.044 14.1 0.0 6.0 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EPE28973.1 - 2.4e-11 43.2 0.6 4.4e-11 42.4 0.6 1.5 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EPE28973.1 - 0.0001 22.1 0.8 2.5 8.2 0.0 4.7 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EPE28973.1 - 0.00043 19.3 0.6 0.025 13.5 0.0 3.8 3 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Band_7 PF01145.25 EPE28974.1 - 1.8e-29 103.0 0.8 2.9e-29 102.4 0.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EPE28974.1 - 1e-23 83.1 1.9 2.5e-23 81.9 1.9 1.7 1 0 0 1 1 1 1 C-terminal region of band_7 DRTGG PF07085.12 EPE28974.1 - 0.053 13.3 0.7 0.75 9.6 0.0 2.4 1 1 0 2 2 2 0 DRTGG domain Pox_A11 PF05061.13 EPE28974.1 - 0.069 12.4 0.7 0.16 11.3 0.7 1.6 1 1 0 1 1 1 0 Poxvirus A11 Protein Band_7_1 PF13421.6 EPE28974.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family zf-U1 PF06220.12 EPE28975.1 - 6.1e-05 22.7 0.5 0.0001 22.0 0.5 1.4 1 0 0 1 1 1 1 U1 zinc finger ADH_N PF08240.12 EPE28976.1 - 7.8e-06 25.7 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE28976.1 - 8.4e-06 25.8 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2314 PF10077.9 EPE28976.1 - 0.032 14.3 0.1 0.068 13.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) Peptidase_M41 PF01434.18 EPE28979.1 - 0.005 16.7 1.1 0.005 16.7 1.1 2.7 2 1 1 3 3 3 1 Peptidase family M41 Apolipoprotein PF01442.18 EPE28979.1 - 0.0068 16.3 13.8 0.06 13.2 6.8 3.8 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain XH PF03469.14 EPE28979.1 - 0.0078 16.1 10.4 0.44 10.4 0.1 3.7 3 1 0 3 3 3 2 XH domain HDC PF02329.16 EPE28979.1 - 0.014 14.4 0.1 0.067 12.2 0.0 1.9 2 0 0 2 2 2 0 Histidine carboxylase PI chain BRX_N PF13713.6 EPE28979.1 - 0.042 13.6 2.1 0.43 10.4 0.5 3.0 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain MHB PF16525.5 EPE28979.1 - 0.045 14.0 0.9 2.6 8.4 0.0 3.4 3 0 0 3 3 3 0 Haemophore, haem-binding DUF948 PF06103.11 EPE28979.1 - 0.061 13.6 8.8 1.1 9.6 0.0 4.6 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DnaI_N PF07319.11 EPE28979.1 - 0.11 13.2 0.4 0.11 13.2 0.4 2.5 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus Globin PF00042.22 EPE28979.1 - 0.26 11.9 5.6 7.1 7.2 0.0 3.7 3 1 1 5 5 5 0 Globin RRF PF01765.19 EPE28979.1 - 3.1 7.7 18.8 29 4.6 0.8 3.8 2 1 1 3 3 3 0 Ribosome recycling factor Mgm101p PF06420.12 EPE28980.1 - 3.5e-87 290.3 0.0 4.5e-87 289.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 BPL_N PF09825.9 EPE28981.1 - 1.2e-151 505.1 0.0 1.5e-151 504.8 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EPE28981.1 - 5.8e-24 84.5 0.0 9.5e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ThuA PF06283.11 EPE28981.1 - 0.054 13.7 0.0 0.13 12.5 0.0 1.6 2 0 0 2 2 2 0 Trehalose utilisation HET PF06985.11 EPE28982.1 - 1.9e-23 83.5 1.1 5.1e-23 82.1 0.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) MIB_HERC2 PF06701.13 EPE28982.1 - 0.27 11.5 2.3 10 6.5 0.0 3.3 3 0 0 3 3 3 0 Mib_herc2 TB2_DP1_HVA22 PF03134.19 EPE28983.1 - 8.4e-24 83.3 7.2 1.3e-23 82.7 7.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TANGO2 PF05742.12 EPE28984.1 - 2.5e-70 237.4 0.0 3e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 DUF4501 PF14946.6 EPE28985.1 - 0.034 14.2 2.2 0.048 13.7 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4501) DUF1772 PF08592.11 EPE28987.1 - 3e-26 92.4 2.6 3.6e-26 92.1 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) YqhR PF11085.8 EPE28987.1 - 0.017 15.1 0.5 0.025 14.5 0.5 1.3 1 0 0 1 1 1 0 Conserved membrane protein YqhR Aldedh PF00171.22 EPE28988.1 - 4.4e-155 516.7 0.1 4.9e-155 516.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RuvC_1 PF18516.1 EPE28988.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 RuvC nuclease domain DUF3445 PF11927.8 EPE28989.1 - 7.5e-68 228.5 0.0 9e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) NTF2 PF02136.20 EPE28990.1 - 1.3e-18 67.7 0.8 1.5e-18 67.5 0.8 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 EPE28990.1 - 0.00065 20.1 0.0 0.00083 19.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4518 PF15008.6 EPE28990.1 - 0.014 14.6 0.5 0.27 10.4 0.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Beta-lactamase PF00144.24 EPE28992.1 - 2.5e-43 148.6 0.3 3.7e-43 148.0 0.3 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EPE28992.1 - 4e-12 46.5 0.0 6.9e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) zf-primase PF09329.11 EPE28993.1 - 3.3e-20 71.6 2.0 6.3e-20 70.7 2.0 1.5 1 0 0 1 1 1 1 Primase zinc finger DUF3381 PF11861.8 EPE28993.1 - 3.4 7.4 12.6 9 6.1 5.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) RNase_H2-Ydr279 PF09468.10 EPE28994.1 - 1.2e-43 149.0 3.4 4.2e-43 147.3 0.8 2.5 1 1 1 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EPE28994.1 - 3e-23 81.9 0.1 1.4e-22 79.7 0.0 2.1 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain SVIP PF15811.5 EPE28994.1 - 0.0058 17.1 6.5 0.015 15.8 6.5 1.6 1 0 0 1 1 1 1 Small VCP/p97-interacting protein DUF4827 PF16109.5 EPE28994.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4827) DASH_Duo1 PF08651.10 EPE28995.1 - 2.3e-32 110.6 2.7 3.1e-32 110.2 2.7 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 Bunya_NS-S PF01104.17 EPE28995.1 - 0.071 12.9 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s DASH_Dad2 PF08654.10 EPE28995.1 - 0.46 10.9 6.2 1.2 9.5 6.2 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad2 TTL PF03133.15 EPE28997.1 - 8.2e-53 179.4 0.0 1.3e-52 178.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 EPE28997.1 - 1.3e-51 175.2 0.0 1.9e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 EPE28997.1 - 0.00022 20.6 0.0 0.0012 18.2 0.0 1.9 2 0 0 2 2 2 1 YheC/D like ATP-grasp Glyco_trans_4_4 PF13579.6 EPE28997.1 - 0.14 12.5 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain NHase_beta PF02211.15 EPE28999.1 - 0.37 10.8 3.5 0.42 10.6 3.5 1.1 1 0 0 1 1 1 0 Nitrile hydratase beta subunit Mito_carr PF00153.27 EPE29000.1 - 2.7e-65 216.3 1.3 7.4e-24 83.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Dna2 PF08696.11 EPE29001.1 - 7.3e-70 234.9 0.1 2e-69 233.5 0.0 1.8 2 0 0 2 2 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 EPE29001.1 - 6e-53 179.4 0.0 1.2e-52 178.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EPE29001.1 - 1.2e-29 103.9 10.3 1.9e-16 60.7 0.1 3.4 2 1 1 3 3 2 2 AAA domain AAA_30 PF13604.6 EPE29001.1 - 4.2e-14 52.7 0.0 1e-13 51.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPE29001.1 - 7.5e-14 52.3 0.1 1.5e-13 51.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 EPE29001.1 - 3.6e-07 30.4 0.1 3.4e-06 27.2 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 EPE29001.1 - 3.7e-07 30.1 2.2 0.34 10.6 0.1 4.0 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EPE29001.1 - 1.9e-05 24.6 0.0 4.6e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 EPE29001.1 - 0.00044 19.9 0.8 0.0012 18.4 0.8 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 EPE29001.1 - 0.00056 20.3 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 EPE29001.1 - 0.0014 18.3 0.2 0.0027 17.4 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PIF1 PF05970.14 EPE29001.1 - 0.0023 17.1 0.1 0.0066 15.7 0.1 1.7 1 1 0 1 1 1 1 PIF1-like helicase Csa1 PF06023.12 EPE29001.1 - 0.0029 17.0 0.1 0.013 14.9 0.1 2.0 1 1 0 1 1 1 1 CRISPR-associated exonuclease Csa1 AAA_7 PF12775.7 EPE29001.1 - 0.0067 16.0 0.0 0.083 12.4 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 EPE29001.1 - 0.011 16.3 0.0 0.047 14.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain ResIII PF04851.15 EPE29001.1 - 0.011 15.7 0.1 0.027 14.5 0.1 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CbiA PF01656.23 EPE29001.1 - 0.015 15.3 0.3 0.043 13.9 0.3 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RuvB_N PF05496.12 EPE29001.1 - 0.017 14.9 0.1 0.04 13.7 0.1 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain cobW PF02492.19 EPE29001.1 - 0.023 14.3 0.1 0.047 13.3 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 EPE29001.1 - 0.04 14.0 0.2 0.13 12.4 0.2 1.8 1 0 0 1 1 1 0 Helicase HerA, central domain DUF2075 PF09848.9 EPE29001.1 - 0.046 13.0 0.0 0.092 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 EPE29001.1 - 0.06 12.9 0.1 0.53 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EPE29001.1 - 0.081 13.1 0.2 0.62 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EPE29001.1 - 0.09 12.7 0.2 0.26 11.2 0.2 1.7 1 0 0 1 1 1 0 NTPase AAA PF00004.29 EPE29001.1 - 0.11 13.0 0.1 0.3 11.5 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 EPE29001.1 - 0.14 11.1 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Sulfatase PF00884.23 EPE29002.1 - 1.6e-64 218.2 0.1 2.1e-64 217.9 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EPE29002.1 - 0.11 12.0 0.0 6.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase DPM3 PF08285.11 EPE29004.1 - 9.9e-36 121.8 0.2 1.1e-35 121.7 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Phage_holin_3_6 PF07332.11 EPE29004.1 - 0.15 12.1 4.6 0.69 10.0 4.7 1.7 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Oxidored-like PF09791.9 EPE29005.1 - 9e-24 82.9 4.7 1.5e-23 82.1 4.7 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal NADH_dehy_S2_C PF06444.11 EPE29006.1 - 0.093 13.3 0.8 0.28 11.7 0.8 1.8 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus MFS_1 PF07690.16 EPE29007.1 - 5.2e-36 124.3 43.4 5.3e-35 121.0 24.0 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE29007.1 - 5.3e-11 42.0 8.6 5.3e-11 42.0 8.6 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 EPE29007.1 - 0.0014 17.1 0.7 0.0031 16.0 0.7 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector Pro_CA PF00484.19 EPE29008.1 - 3.9e-07 30.5 0.3 3.3e-06 27.5 0.3 2.1 1 1 0 1 1 1 1 Carbonic anhydrase RRM_1 PF00076.22 EPE29009.1 - 2.4e-09 36.9 0.1 4.4e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EPE29009.1 - 2.6e-05 24.1 0.0 5.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EPE29009.1 - 0.003 17.4 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EPE29009.1 - 0.023 14.8 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif FAM110_C PF14160.6 EPE29009.1 - 0.52 11.4 4.3 0.3 12.2 0.6 2.4 2 1 0 2 2 2 0 Centrosome-associated C terminus ATG16 PF08614.11 EPE29010.1 - 0.0022 18.2 0.8 0.0022 18.2 0.8 2.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF2046 PF09755.9 EPE29010.1 - 0.0034 16.6 2.0 0.098 11.9 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) FlaC_arch PF05377.11 EPE29010.1 - 0.33 11.4 1.0 0.5 10.8 0.1 1.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Uds1 PF15456.6 EPE29010.1 - 0.74 10.0 7.4 0.44 10.7 1.1 2.4 2 0 0 2 2 2 0 Up-regulated During Septation TSC22 PF01166.18 EPE29010.1 - 1.4 9.3 6.0 0.92 9.9 1.1 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family Rad10 PF03834.14 EPE29012.1 - 2.4e-47 159.7 0.5 3.3e-47 159.2 0.5 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EPE29012.1 - 0.05 14.2 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain SLAC1 PF03595.17 EPE29013.1 - 8.7e-92 307.8 58.4 1.2e-91 307.4 58.4 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel SET PF00856.28 EPE29014.1 - 5.3e-09 36.7 0.6 3.2e-08 34.1 0.0 2.5 2 1 0 2 2 2 1 SET domain Ribosomal_L13e PF01294.18 EPE29015.1 - 9.3e-77 256.9 1.0 9.3e-77 256.9 1.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L13e DUF1664 PF07889.12 EPE29017.1 - 0.011 15.8 0.7 0.031 14.3 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 EPE29017.1 - 0.015 15.7 0.2 0.047 14.1 0.2 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF848 PF05852.11 EPE29017.1 - 0.52 10.4 5.5 0.15 12.1 0.7 2.4 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) XhlA PF10779.9 EPE29017.1 - 6.5 7.0 7.4 31 4.9 1.6 2.8 2 1 1 3 3 3 0 Haemolysin XhlA DUF4398 PF14346.6 EPE29018.1 - 0.014 16.0 0.7 4.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) DUF4349 PF14257.6 EPE29018.1 - 0.038 13.4 7.0 0.048 13.1 1.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) FlbD PF06289.11 EPE29020.1 - 0.21 11.2 0.2 3 7.5 0.1 2.3 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins Cob_adeno_trans PF01923.18 EPE29021.1 - 0.0038 17.4 1.7 0.006 16.7 1.7 1.4 1 0 0 1 1 1 1 Cobalamin adenosyltransferase FerA PF08165.11 EPE29021.1 - 0.1 12.5 2.5 0.21 11.6 0.2 2.6 2 1 0 2 2 2 0 FerA (NUC095) domain SieB PF14163.6 EPE29021.1 - 0.5 9.8 3.0 0.51 9.8 0.7 2.0 2 0 0 2 2 2 0 Super-infection exclusion protein B DUF3847 PF12958.7 EPE29021.1 - 0.55 10.4 11.0 2.3 8.4 1.7 3.3 2 2 0 3 3 3 0 Protein of unknown function (DUF3847) Snapin_Pallidin PF14712.6 EPE29021.1 - 1.1 9.8 9.7 0.11 12.9 3.5 2.6 2 1 1 3 3 3 0 Snapin/Pallidin bZIP_1 PF00170.21 EPE29021.1 - 2 8.5 15.4 0.19 11.9 3.9 3.3 3 0 0 3 3 3 0 bZIP transcription factor TSC22 PF01166.18 EPE29021.1 - 2.4 8.5 10.1 5.4 7.4 0.2 2.9 3 0 0 3 3 3 0 TSC-22/dip/bun family Sec34 PF04136.15 EPE29021.1 - 2.7 7.9 10.7 2.8 7.8 2.5 3.0 2 2 1 3 3 3 0 Sec34-like family APG6_N PF17675.1 EPE29021.1 - 2.8 8.5 19.6 0.31 11.6 5.2 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region XhlA PF10779.9 EPE29021.1 - 2.9 8.2 6.2 18 5.7 0.9 3.0 3 0 0 3 3 3 0 Haemolysin XhlA Leu_zip PF15294.6 EPE29021.1 - 4.1 6.8 18.4 0.63 9.5 5.7 2.8 1 1 1 3 3 3 0 Leucine zipper DivIC PF04977.15 EPE29021.1 - 5.6 6.8 15.3 0.84 9.4 0.5 3.5 4 0 0 4 4 4 0 Septum formation initiator YabA PF06156.13 EPE29021.1 - 7.2 7.3 15.2 4.7 7.9 3.9 3.1 1 1 2 3 3 3 0 Initiation control protein YabA zf-RING_2 PF13639.6 EPE29022.1 - 4.5e-11 42.9 5.1 9.3e-11 41.9 5.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EPE29022.1 - 5.4e-08 33.0 4.0 1.3e-07 31.7 4.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EPE29022.1 - 1e-06 28.7 4.1 2e-06 27.7 4.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EPE29022.1 - 1.7e-05 24.6 4.3 3.7e-05 23.5 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE29022.1 - 9.1e-05 22.3 4.4 0.00015 21.6 4.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EPE29022.1 - 0.00021 21.0 5.9 0.00081 19.2 5.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EPE29022.1 - 0.00022 20.9 0.2 0.00056 19.6 0.2 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EPE29022.1 - 0.00026 20.8 3.2 0.00046 20.0 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EPE29022.1 - 0.0003 20.8 1.5 0.0006 19.8 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SDA1 PF05285.12 EPE29022.1 - 0.00072 19.1 22.2 0.0012 18.3 22.2 1.3 1 0 0 1 1 1 1 SDA1 zf-Nse PF11789.8 EPE29022.1 - 0.017 14.9 0.8 0.037 13.8 0.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EPE29022.1 - 0.044 14.0 5.0 0.19 11.9 5.2 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Tmpp129 PF10272.9 EPE29022.1 - 0.074 12.3 0.9 0.12 11.7 0.9 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Nop14 PF04147.12 EPE29022.1 - 0.19 9.9 26.5 0.31 9.2 26.5 1.3 1 0 0 1 1 1 0 Nop14-like family DUF2267 PF10025.9 EPE29022.1 - 0.19 12.0 2.8 0.21 11.9 0.2 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Prok-RING_4 PF14447.6 EPE29022.1 - 0.34 10.8 5.1 1.2 9.1 5.1 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Cnd2 PF05786.14 EPE29022.1 - 0.6 8.7 17.9 1.1 7.9 17.9 1.3 1 0 0 1 1 1 0 Condensin complex subunit 2 SAPS PF04499.15 EPE29022.1 - 3.7 6.2 7.9 7.4 5.2 7.9 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein KxDL PF10241.9 EPE29023.1 - 0.12 12.7 0.1 12 6.3 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein HgmA PF04209.13 EPE29024.1 - 5e-203 674.5 0.0 5.7e-203 674.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Fungal_trans PF04082.18 EPE29025.1 - 1.7e-15 56.8 0.0 2.7e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE29025.1 - 4.4e-08 33.1 13.9 7.6e-08 32.3 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.10 EPE29025.1 - 0.16 12.3 0.1 0.34 11.2 0.1 1.5 1 0 0 1 1 1 0 HalX domain DAO PF01266.24 EPE29026.1 - 1.1e-51 176.5 0.4 1.3e-51 176.3 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EPE29026.1 - 0.0014 18.6 0.3 0.23 11.4 0.1 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EPE29026.1 - 0.03 14.6 0.1 0.03 14.6 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EPE29026.1 - 0.17 10.5 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Aldo_ket_red PF00248.21 EPE29028.1 - 5.4e-66 222.8 0.0 6.5e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.22 EPE29029.1 - 6.9e-60 203.1 0.0 7.8e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAA_hydrolase PF01557.18 EPE29030.1 - 2e-49 168.2 0.0 2.8e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EPE29030.1 - 2.6e-28 98.3 0.0 3.9e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal DUF4300 PF14133.6 EPE29030.1 - 0.11 12.2 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) RCC1 PF00415.18 EPE29031.1 - 8.8e-56 186.3 1.8 4.3e-12 46.5 0.0 8.0 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EPE29031.1 - 5.1e-35 118.6 28.2 9.6e-11 41.2 0.2 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat FUSC_2 PF13515.6 EPE29032.1 - 3e-16 59.7 31.9 2.2e-13 50.5 10.3 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EPE29032.1 - 1.4e-07 31.5 0.0 7e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 EPE29032.1 - 1.8e-05 24.0 4.7 1.8e-05 24.0 4.7 4.1 4 1 0 4 4 4 2 Putative ER transporter, 6TM, N-terminal FUSC PF04632.12 EPE29032.1 - 0.00021 20.0 12.5 0.00021 20.0 12.5 2.3 3 0 0 3 3 3 1 Fusaric acid resistance protein family ALMT PF11744.8 EPE29032.1 - 0.23 10.3 3.8 0.52 9.1 3.8 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF478 PF04334.12 EPE29032.1 - 1.6 8.9 8.4 0.81 9.8 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF478) SIR2 PF02146.17 EPE29033.1 - 3.6e-57 193.1 0.0 5.4e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EPE29033.1 - 0.00011 21.9 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EPE29033.1 - 0.00085 19.1 0.0 0.84 9.4 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Phage_tail_APC PF16778.5 EPE29033.1 - 0.14 12.1 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone protein HET PF06985.11 EPE29034.1 - 3.3e-22 79.4 0.0 7.3e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SRR1 PF07985.12 EPE29035.1 - 1.2e-08 34.9 0.0 2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 SRR1 APC1_C PF18122.1 EPE29035.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain Cation_ATPase_C PF00689.21 EPE29037.1 - 6.2e-44 149.9 7.8 6.2e-44 149.9 7.8 2.5 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EPE29037.1 - 7.7e-34 116.8 0.2 7.7e-34 116.8 0.2 3.2 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 EPE29037.1 - 1.7e-24 85.7 0.0 3.4e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EPE29037.1 - 2.6e-20 73.6 2.6 3e-20 73.4 1.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EPE29037.1 - 4.2e-06 26.7 0.3 0.00016 21.5 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EPE29037.1 - 2.8e-05 23.7 0.1 0.00043 19.9 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus LptF_LptG PF03739.14 EPE29037.1 - 0.014 14.3 0.8 0.039 12.8 0.8 1.7 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DevR PF01905.16 EPE29037.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 Colicin_V PF02674.16 EPE29037.1 - 0.13 12.2 0.0 0.13 12.2 0.0 2.6 3 0 0 3 3 2 0 Colicin V production protein DUF3500 PF12006.8 EPE29037.1 - 0.16 11.5 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) DUF2976 PF11190.8 EPE29037.1 - 4.6 7.1 7.9 0.4 10.5 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) ESSS PF10183.9 EPE29038.1 - 7.3e-17 61.5 0.0 8.2e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3961 PF13106.6 EPE29038.1 - 0.58 9.9 3.4 0.99 9.1 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Aminotran_4 PF01063.19 EPE29039.1 - 5.8e-32 111.3 0.0 8.1e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 EPE29040.1 - 1.1e-17 64.3 0.0 3.8e-17 62.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE29040.1 - 2.7e-08 33.4 0.0 2.5e-07 30.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DCB PF16213.5 EPE29040.1 - 0.058 13.1 2.6 0.091 12.4 0.1 2.4 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 CBM60 PF16841.5 EPE29042.1 - 0.086 13.3 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Ca-dependent carbohydrate-binding module xylan-binding bZIP_2 PF07716.15 EPE29043.1 - 0.025 14.7 8.7 0.08 13.0 0.4 2.3 2 0 0 2 2 2 0 Basic region leucine zipper SIKE PF05769.11 EPE29043.1 - 0.1 12.5 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 SIKE family bZIP_1 PF00170.21 EPE29043.1 - 1.6 8.9 7.1 14 5.9 7.1 2.0 1 1 0 1 1 1 0 bZIP transcription factor MFS_1 PF07690.16 EPE29044.1 - 1.9e-18 66.6 44.6 3.6e-10 39.3 21.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily BatA PF07584.11 EPE29044.1 - 0.15 12.5 2.1 0.2 12.1 0.2 2.2 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal NAD_binding_6 PF08030.12 EPE29044.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Rhodanese PF00581.20 EPE29045.1 - 0.00016 22.1 0.0 0.0003 21.3 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain ImpA_N PF06812.12 EPE29045.1 - 0.16 12.1 0.2 2.4 8.3 0.0 2.1 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system SBF PF01758.16 EPE29046.1 - 4.7e-53 179.8 8.9 4.7e-53 179.8 8.9 2.1 2 1 1 3 3 3 1 Sodium Bile acid symporter family PRKCSH-like PF12999.7 EPE29047.1 - 1.3e-45 155.3 3.4 2e-26 92.9 0.2 2.8 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EPE29047.1 - 1.4e-28 99.5 4.5 2.4e-28 98.8 1.1 2.6 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EPE29047.1 - 4.1e-10 40.5 2.7 2e-09 38.3 2.7 2.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 EPE29047.1 - 0.00053 19.9 0.5 0.001 19.0 0.5 1.4 1 0 0 1 1 1 1 Autophagy-related protein 27 RILP PF11461.8 EPE29047.1 - 0.11 12.7 0.9 0.36 11.1 0.9 1.9 1 0 0 1 1 1 0 Rab interacting lysosomal protein Snapin_Pallidin PF14712.6 EPE29047.1 - 0.11 12.9 0.9 2 8.9 0.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin ydhR PF08803.11 EPE29047.1 - 0.13 12.2 0.3 0.4 10.6 0.1 1.9 2 0 0 2 2 2 0 Putative mono-oxygenase ydhR Spc7 PF08317.11 EPE29047.1 - 0.14 11.0 4.1 0.095 11.6 2.0 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 EPE29047.1 - 0.54 10.3 6.8 1.7 8.7 1.4 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 EPE29047.1 - 1.5 8.8 4.5 2.3 8.2 0.4 2.6 2 0 0 2 2 2 0 Prefoldin subunit Fmp27_WPPW PF10359.9 EPE29047.1 - 2.3 7.0 7.1 38 3.0 7.1 2.1 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ldl_recept_a PF00057.18 EPE29047.1 - 3.5 7.9 9.1 2.9 8.2 1.5 2.9 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Rtf2 PF04641.12 EPE29051.1 - 1.2e-57 195.3 1.8 1.5e-57 194.9 1.8 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 EPE29051.1 - 2.2e-06 27.4 0.3 0.021 14.6 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit DUF3913 PF13052.6 EPE29051.1 - 0.06 13.6 0.2 0.12 12.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3913) zf-RING_5 PF14634.6 EPE29051.1 - 0.065 13.2 0.1 0.25 11.4 0.1 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EPE29051.1 - 0.22 11.6 1.7 0.37 10.9 0.1 2.2 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_11 PF17123.5 EPE29051.1 - 0.26 11.0 0.8 1.5 8.6 0.1 2.3 2 0 0 2 2 2 0 RING-like zinc finger FAT PF02259.23 EPE29052.1 - 1.9e-128 428.5 2.4 4.9e-128 427.2 2.4 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EPE29052.1 - 3.8e-71 239.8 0.1 7.2e-71 238.9 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EPE29052.1 - 4.5e-71 238.0 6.9 6.1e-65 218.0 1.3 5.1 5 1 1 6 6 6 3 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EPE29052.1 - 6e-43 145.3 3.2 2.6e-42 143.2 0.0 3.7 3 1 1 4 4 4 1 FKBP12-rapamycin binding domain HEAT PF02985.22 EPE29052.1 - 2.2e-16 58.5 21.4 0.00016 21.7 0.0 12.6 14 0 0 14 14 13 3 HEAT repeat HEAT_2 PF13646.6 EPE29052.1 - 2.6e-16 59.8 16.2 0.00015 22.1 0.0 9.8 8 1 2 10 10 10 4 HEAT repeats FATC PF02260.20 EPE29052.1 - 2.7e-10 39.9 0.2 9.5e-10 38.1 0.2 2.0 1 0 0 1 1 1 1 FATC domain Cnd1 PF12717.7 EPE29052.1 - 3.2e-09 37.0 2.4 1.7 8.6 0.0 7.1 6 1 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EPE29052.1 - 1.2e-06 28.9 21.1 0.0028 18.1 0.0 10.6 9 3 3 12 12 12 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EPE29052.1 - 3.5e-05 24.3 0.5 39 4.9 0.0 7.3 7 2 1 8 8 7 0 Vacuolar 14 Fab1-binding region UME PF08064.13 EPE29052.1 - 9.5e-05 22.2 1.7 1.9 8.5 0.0 6.9 7 1 1 8 8 8 1 UME (NUC010) domain Adaptin_N PF01602.20 EPE29052.1 - 0.0001 21.1 10.2 0.0018 17.0 0.2 4.4 4 1 0 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.8 EPE29052.1 - 0.0004 20.0 0.1 1 8.9 0.0 5.1 4 1 1 5 5 5 1 CLASP N terminal ANAPC3 PF12895.7 EPE29052.1 - 0.058 13.6 4.9 2.5 8.4 0.5 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Sec7_N PF12783.7 EPE29052.1 - 0.95 9.4 5.3 11 5.9 0.0 4.5 4 1 1 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_7 PF13176.6 EPE29052.1 - 4.1 7.7 5.0 10 6.4 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 EPE29053.1 - 1.1e-62 211.7 0.0 1.6e-62 211.2 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE29053.1 - 2e-43 148.1 0.2 3.1e-43 147.5 0.2 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE29053.1 - 1.4e-11 44.6 0.2 2.2e-11 44.0 0.2 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE29053.1 - 0.011 14.9 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EPE29053.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HHH_5 PF14520.6 EPE29053.1 - 0.024 15.2 0.6 0.26 11.9 0.1 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain Pam16 PF03656.13 EPE29054.1 - 3.8e-35 120.7 1.1 5e-35 120.3 1.1 1.1 1 0 0 1 1 1 1 Pam16 14-3-3 PF00244.20 EPE29055.1 - 1.3e-107 358.4 1.5 1.5e-107 358.1 1.5 1.1 1 0 0 1 1 1 1 14-3-3 protein FlaC_arch PF05377.11 EPE29055.1 - 0.14 12.6 0.8 0.3 11.5 0.8 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) AflR PF08493.10 EPE29056.1 - 4.7 6.6 8.8 6.1 6.2 7.3 1.7 1 1 0 1 1 1 0 Aflatoxin regulatory protein Suf PF05843.14 EPE29057.1 - 1.2e-05 25.5 10.5 0.0011 19.1 0.1 3.2 2 1 0 3 3 3 2 Suppressor of forked protein (Suf) SNAP PF14938.6 EPE29057.1 - 0.00038 20.0 0.7 0.002 17.6 0.6 2.0 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 EPE29057.1 - 0.00054 20.6 6.3 0.19 12.6 0.1 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat c-SKI_SMAD_bind PF08782.10 EPE29057.1 - 2 8.7 4.7 23 5.3 0.5 3.6 2 1 0 2 2 2 0 c-SKI Smad4 binding domain HET PF06985.11 EPE29058.1 - 3.6e-25 89.0 0.6 7.4e-25 88.0 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) FlpD PF02662.16 EPE29059.1 - 0.087 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit zf-RING_2 PF13639.6 EPE29060.1 - 8.2e-10 38.9 2.5 8.2e-10 38.9 2.5 2.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EPE29060.1 - 3.1e-08 33.8 3.8 3.1e-08 33.8 3.8 2.7 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EPE29060.1 - 3.2e-07 30.2 1.6 3.2e-07 30.2 1.6 2.2 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EPE29060.1 - 8.6e-07 28.7 1.8 3.1e-06 26.9 1.8 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EPE29060.1 - 4.8e-06 26.3 5.1 0.00014 21.6 5.5 2.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE29060.1 - 5.5e-06 26.1 5.1 5.5e-06 26.1 5.1 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE29060.1 - 5.6e-05 23.1 0.1 5.6e-05 23.1 0.1 2.7 3 1 1 4 4 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EPE29060.1 - 0.00073 19.4 3.6 0.00073 19.4 3.6 2.7 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EPE29060.1 - 0.004 17.2 3.0 0.004 17.2 3.0 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF971 PF06155.12 EPE29060.1 - 0.051 14.2 0.7 1 10.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF971) zf-RING_6 PF14835.6 EPE29060.1 - 0.053 13.4 2.2 0.14 12.0 2.2 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 EPE29060.1 - 0.066 12.9 1.2 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 P-11 zinc finger DNA_pol3_a_NII PF11490.8 EPE29060.1 - 0.12 12.3 0.0 6.6 6.7 0.0 2.5 2 1 0 2 2 2 0 DNA polymerase III polC-type N-terminus II zf-C3HC4_4 PF15227.6 EPE29060.1 - 0.19 11.9 4.3 0.11 12.6 1.2 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EPE29060.1 - 1.8 8.5 6.4 0.16 11.8 0.8 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 EPE29060.1 - 2.5 8.3 6.5 1.9 8.7 2.9 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 EPE29060.1 - 3.9 7.3 8.7 0.18 11.6 1.3 2.7 3 1 0 3 3 3 0 RING-like zinc finger zf-rbx1 PF12678.7 EPE29061.1 - 1.7e-07 31.4 1.6 1.7e-07 31.4 1.6 2.3 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EPE29061.1 - 4.4e-07 30.1 2.6 4.4e-07 30.1 2.6 3.5 3 1 1 4 4 4 1 Ring finger domain zf-ANAPC11 PF12861.7 EPE29061.1 - 2e-06 27.8 0.3 2e-06 27.8 0.3 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EPE29061.1 - 4.6e-06 26.5 1.1 4.6e-06 26.5 1.1 3.1 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EPE29061.1 - 1.9e-05 24.4 0.8 1.9e-05 24.4 0.8 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE29061.1 - 4.3e-05 23.3 1.5 4.3e-05 23.3 1.5 2.8 3 1 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EPE29061.1 - 5.3e-05 23.2 4.1 0.0036 17.3 0.0 3.6 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EPE29061.1 - 7.8e-05 22.4 0.4 7.8e-05 22.4 0.4 4.2 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPE29061.1 - 0.0061 16.4 4.3 0.0061 16.4 4.3 3.3 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPE29061.1 - 0.073 13.2 0.3 0.073 13.2 0.3 2.8 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EPE29061.1 - 0.11 12.1 5.9 0.29 10.8 0.2 2.9 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type RhoGAP PF00620.27 EPE29062.1 - 2e-42 144.6 0.0 5.3e-42 143.2 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 EPE29062.1 - 3e-12 47.0 0.0 6.7e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF3450 PF11932.8 EPE29062.1 - 0.034 13.4 1.4 0.065 12.5 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-RING_2 PF13639.6 EPE29064.1 - 5.6e-10 39.4 5.9 5.6e-10 39.4 5.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EPE29064.1 - 2.4e-05 24.5 3.6 2.4e-05 24.5 3.6 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EPE29064.1 - 2.4e-05 24.1 3.8 2.4e-05 24.1 3.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE29064.1 - 0.00018 21.3 4.0 0.00018 21.3 4.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE29064.1 - 0.0039 17.0 3.0 0.011 15.5 3.0 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EPE29064.1 - 0.004 17.1 3.3 0.017 15.1 0.9 2.9 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 EPE29064.1 - 0.071 12.9 0.9 0.35 10.7 1.2 2.1 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4 PF00097.25 EPE29064.1 - 0.098 12.5 8.7 0.039 13.8 4.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Baculo_RING PF05883.11 EPE29064.1 - 0.14 12.1 1.1 7.1 6.6 0.3 2.5 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING_5 PF14634.6 EPE29064.1 - 0.16 11.9 7.9 0.15 12.0 4.8 2.3 2 0 0 2 2 2 0 zinc-RING finger domain mIF3 PF14877.6 EPE29064.1 - 0.27 10.9 1.1 14 5.3 0.2 2.3 2 0 0 2 2 2 0 Mitochondrial translation initiation factor zf-ANAPC11 PF12861.7 EPE29064.1 - 0.56 10.3 2.6 2.3 8.4 2.6 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2358 PF10184.9 EPE29065.1 - 0.052 13.8 0.7 0.14 12.4 0.7 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) zf-RING_2 PF13639.6 EPE29066.1 - 6.3e-11 42.4 9.3 6.3e-11 42.4 9.3 1.9 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 EPE29066.1 - 5.2e-10 39.5 6.2 1.1e-09 38.4 6.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EPE29066.1 - 7.3e-06 25.8 7.0 7.3e-06 25.8 7.0 2.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EPE29066.1 - 1.2e-05 25.1 8.6 1.2e-05 25.1 8.6 2.3 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE29066.1 - 4.8e-05 23.1 7.9 4.8e-05 23.1 7.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE29066.1 - 0.00015 21.7 13.9 0.00023 21.1 8.7 3.0 3 0 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EPE29066.1 - 0.0002 21.1 6.4 0.0002 21.1 6.4 2.2 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EPE29066.1 - 0.00022 21.2 2.2 0.0006 19.8 2.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EPE29066.1 - 0.00022 21.0 6.2 0.00022 21.0 6.2 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EPE29066.1 - 0.0017 18.0 9.0 0.0018 18.0 6.3 2.3 2 0 0 2 2 2 1 RING-like zinc finger Rad50_zn_hook PF04423.14 EPE29066.1 - 0.046 13.6 3.0 3.9 7.4 0.1 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif YdjO PF14169.6 EPE29066.1 - 0.074 12.8 2.1 2.3 8.0 0.3 2.6 2 0 0 2 2 2 0 Cold-inducible protein YdjO zf-RING_4 PF14570.6 EPE29066.1 - 0.17 11.7 6.4 0.36 10.7 6.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 EPE29066.1 - 0.19 11.6 3.7 0.46 10.3 3.7 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 EPE29066.1 - 0.25 11.0 4.5 0.52 10.0 4.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 EPE29066.1 - 0.26 11.5 6.4 5.8 7.1 4.4 2.9 2 1 1 3 3 3 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EPE29066.1 - 1.4 9.1 12.0 1.8 8.8 9.0 2.7 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING F-box PF00646.33 EPE29067.1 - 0.0033 17.2 0.0 0.0081 16.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPE29067.1 - 0.01 15.7 1.8 0.05 13.5 0.0 2.8 3 0 0 3 3 3 0 F-box-like zf-RING_2 PF13639.6 EPE29068.1 - 2.4e-07 30.9 8.6 2.4e-07 30.9 8.6 2.6 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 EPE29068.1 - 0.00015 21.9 6.3 0.00015 21.9 6.3 2.5 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EPE29068.1 - 0.00043 20.1 8.3 0.0005 19.9 4.8 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EPE29068.1 - 0.0016 18.5 0.6 0.0042 17.1 0.6 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EPE29068.1 - 0.0019 18.0 6.4 0.0019 18.0 6.4 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE29068.1 - 0.0035 17.2 2.3 0.0035 17.2 2.3 2.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EPE29068.1 - 0.011 15.6 4.5 0.011 15.6 4.5 3.1 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE29069.1 - 8.7e-09 35.6 5.9 8.7e-09 35.6 5.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EPE29069.1 - 1.3e-07 31.8 5.4 3.3e-07 30.5 5.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EPE29069.1 - 2.9e-06 27.0 0.9 2.9e-06 27.0 0.9 2.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE29069.1 - 2e-05 24.3 4.3 2e-05 24.3 4.3 2.3 2 1 1 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EPE29069.1 - 3.1e-05 23.7 4.2 3.1e-05 23.7 4.2 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE29069.1 - 0.00015 21.7 0.8 0.00015 21.7 0.8 3.5 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EPE29069.1 - 0.00019 21.2 1.4 0.00019 21.2 1.4 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE29069.1 - 0.0003 20.7 3.6 0.0003 20.7 3.6 2.3 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EPE29069.1 - 0.0072 16.5 0.9 0.0072 16.5 0.9 2.3 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 EPE29069.1 - 0.028 14.3 0.1 0.06 13.2 0.1 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 EPE29069.1 - 0.039 13.8 2.4 0.25 11.2 2.3 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EPE29069.1 - 0.05 13.7 1.4 0.13 12.3 1.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger IL28A PF15177.6 EPE29069.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Interleukin-28A FANCL_C PF11793.8 EPE29069.1 - 0.23 11.7 2.9 1 9.6 2.9 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EPE29069.1 - 5.9 6.6 11.1 8.8 6.0 7.4 2.8 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type HET PF06985.11 EPE29070.1 - 7.6e-27 94.5 0.4 1.2e-26 93.8 0.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DnaJ PF00226.31 EPE29071.1 - 2.5e-08 33.9 0.3 2.5e-08 33.9 0.3 2.6 2 1 0 2 2 2 1 DnaJ domain Ada3 PF10198.9 EPE29071.1 - 0.0055 16.8 0.6 2.4 8.3 0.0 2.4 2 0 0 2 2 2 2 Histone acetyltransferases subunit 3 Nexin_C PF08628.12 EPE29071.1 - 0.034 14.7 0.4 0.18 12.4 0.1 2.1 2 0 0 2 2 2 0 Sorting nexin C terminal RAMP4 PF06624.12 EPE29071.1 - 0.11 12.6 9.2 0.91 9.6 2.4 3.3 3 0 0 3 3 3 0 Ribosome associated membrane protein RAMP4 DUF4661 PF15576.6 EPE29071.1 - 2 8.3 5.1 0.27 11.1 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) PRA1 PF03208.19 EPE29072.1 - 1.9e-35 121.6 0.1 2.4e-35 121.3 0.1 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF4407 PF14362.6 EPE29073.1 - 0.027 13.9 0.3 0.046 13.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DnaJ PF00226.31 EPE29074.1 - 2.1e-20 72.6 1.6 4.1e-20 71.6 1.6 1.5 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 EPE29074.1 - 0.038 14.3 1.6 0.056 13.7 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 EPE29074.1 - 0.053 13.7 4.8 0.11 12.6 4.8 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Nucleoporin_FG PF13634.6 EPE29075.1 - 0.0025 18.6 7.1 0.0042 17.9 7.1 1.4 1 0 0 1 1 1 1 Nucleoporin FG repeat region FAA_hydrolase PF01557.18 EPE29076.1 - 2.6e-63 213.6 0.0 3.1e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 EPE29076.1 - 0.051 14.0 0.1 0.087 13.3 0.1 1.3 1 0 0 1 1 1 0 Type II transport protein GspH Complex1_LYR PF05347.15 EPE29077.1 - 5.5e-13 48.7 1.2 1.4e-12 47.5 1.2 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EPE29077.1 - 0.00014 22.6 0.9 0.00063 20.4 0.9 2.2 1 0 0 1 1 1 1 Complex1_LYR-like BTB PF00651.31 EPE29078.1 - 0.015 15.5 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Lipase_3 PF01764.25 EPE29082.1 - 3.1e-28 98.4 0.0 4.6e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 EPE29082.1 - 0.0025 18.0 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EPE29082.1 - 0.005 17.5 0.0 0.0072 16.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE29082.1 - 0.0058 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase PF00151.19 EPE29082.1 - 0.012 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipase DUF2974 PF11187.8 EPE29082.1 - 0.14 11.7 0.0 1 8.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) HATPase_c PF02518.26 EPE29083.1 - 5.6e-18 65.5 0.0 7.5e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPE29083.1 - 1.8e-14 53.9 0.1 5.3e-14 52.4 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPE29083.1 - 0.00017 21.6 0.2 0.00065 19.7 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EPE29083.1 - 0.002 18.0 0.0 0.0052 16.6 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 EPE29083.1 - 0.0097 16.2 0.0 0.023 15.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain Syja_N PF02383.18 EPE29084.1 - 4.9e-75 252.8 0.0 1.1e-74 251.7 0.0 1.6 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 EPE29084.1 - 4.3e-09 36.2 0.0 8.3e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NUDE_C PF04880.13 EPE29084.1 - 1.1 9.7 11.7 2.7 8.4 11.7 1.6 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region MFS_1 PF07690.16 EPE29085.1 - 3.3e-10 39.4 43.8 3.7e-09 36.0 37.1 3.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPE29085.1 - 0.00027 19.5 14.1 0.00056 18.5 14.1 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF5316 PF17247.2 EPE29085.1 - 0.17 11.9 2.2 2.4 8.2 0.6 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5316) His_Phos_1 PF00300.22 EPE29086.1 - 1.1e-11 44.8 0.0 5.2e-10 39.3 0.0 2.6 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) NPR3 PF03666.13 EPE29086.1 - 3.6 6.3 6.5 5.6 5.6 6.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 EPE29086.1 - 9 4.5 5.9 13 3.9 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4990 PF16380.5 EPE29087.1 - 0.0017 18.5 0.0 0.0028 17.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function PTR2 PF00854.21 EPE29088.1 - 2.2e-78 263.8 9.4 3e-78 263.4 9.4 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EPE29088.1 - 2e-08 33.6 19.2 2.3e-07 30.1 19.0 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.28 EPE29089.1 - 3.4e-98 329.0 0.0 4e-98 328.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE29089.1 - 5.2e-16 59.4 0.2 1.2e-15 58.3 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP11 PF06644.11 EPE29090.1 - 1.4e-100 336.6 0.0 1.6e-100 336.4 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein RHH_1 PF01402.21 EPE29090.1 - 0.019 14.9 0.5 0.13 12.2 0.3 2.5 1 1 1 2 2 2 0 Ribbon-helix-helix protein, copG family EHN PF06441.12 EPE29090.1 - 0.025 15.0 0.8 0.13 12.6 0.1 2.1 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Cas_Cas02710 PF09670.10 EPE29090.1 - 0.066 12.0 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Mito_fiss_reg PF05308.11 EPE29090.1 - 0.18 11.8 3.6 0.26 11.3 3.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Proteasome PF00227.26 EPE29091.1 - 8.2e-45 152.6 0.1 1.5e-31 109.3 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EPE29091.1 - 1.1e-11 44.1 0.0 3.1e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature S-methyl_trans PF02574.16 EPE29093.1 - 3.8e-55 187.6 0.0 4.4e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Mit_KHE1 PF10173.9 EPE29093.1 - 0.19 11.8 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related RTA1 PF04479.13 EPE29094.1 - 1.8e-61 207.4 11.0 1.8e-61 207.4 11.0 1.7 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.8 EPE29094.1 - 0.0012 17.7 0.1 0.0029 16.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE29094.1 - 0.004 17.2 1.3 0.0077 16.3 1.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 EPE29096.1 - 0.15 12.0 0.4 0.28 11.1 0.4 1.4 1 0 0 1 1 1 0 PHD-finger BTB PF00651.31 EPE29097.1 - 5.4e-10 39.5 0.1 9.6e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EPE29098.1 - 0.00016 21.9 0.1 0.00031 21.0 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF2065 PF09838.9 EPE29098.1 - 0.18 11.8 0.0 0.46 10.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) Copine PF07002.16 EPE29099.1 - 0.013 15.0 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Copine BTB PF00651.31 EPE29100.1 - 0.012 15.8 0.1 0.03 14.5 0.1 1.6 1 0 0 1 1 1 0 BTB/POZ domain M_domain PF12938.7 EPE29101.1 - 0.95 9.2 4.5 4 7.1 0.2 1.9 1 1 0 2 2 2 0 M domain of GW182 DUF1667 PF07892.11 EPE29102.1 - 0.017 15.2 0.6 2.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1667) WD40 PF00400.32 EPE29103.1 - 1e-52 174.9 37.9 3e-09 37.3 1.8 9.3 9 1 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE29103.1 - 7.5e-19 67.8 5.5 0.00057 20.1 0.6 5.8 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE29103.1 - 4.8e-10 39.6 0.5 0.00027 20.9 0.0 3.9 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EPE29103.1 - 1.6e-07 30.3 6.3 0.022 13.4 0.3 4.5 3 2 1 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EPE29103.1 - 0.00017 21.0 0.0 2.3 7.5 0.0 3.4 3 0 0 3 3 3 3 WD40-like domain NLE PF08154.12 EPE29103.1 - 0.0021 18.5 0.0 0.0045 17.5 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.11 EPE29103.1 - 0.0028 17.9 0.1 0.6 10.3 0.0 2.6 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain Ge1_WD40 PF16529.5 EPE29103.1 - 0.009 15.0 1.1 15 4.4 0.0 4.2 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EPE29103.1 - 0.047 13.6 1.4 52 3.9 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 EPE29103.1 - 0.22 12.1 1.4 3.3 8.3 0.2 3.5 4 0 0 4 4 4 0 PQQ-like domain MutS_V PF00488.21 EPE29104.1 - 1.1e-61 208.2 0.5 1.8e-61 207.5 0.5 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EPE29104.1 - 7.9e-26 91.5 1.0 7.9e-26 91.5 1.0 1.9 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EPE29104.1 - 1.8e-09 38.0 0.0 1.1e-08 35.4 0.0 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EPE29104.1 - 0.00015 22.0 0.3 0.00032 21.0 0.3 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 EPE29104.1 - 0.089 12.4 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cyclin PF08613.11 EPE29105.1 - 1.6e-39 135.9 3.0 2.1e-24 86.7 0.2 2.9 3 0 0 3 3 3 2 Cyclin Proteasome PF00227.26 EPE29107.1 - 1.7e-47 161.4 0.2 2e-47 161.2 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Flavodoxin_1 PF00258.25 EPE29107.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin Evr1_Alr PF04777.13 EPE29108.1 - 2.6e-27 95.2 0.2 4e-27 94.6 0.2 1.3 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC1 PF18769.1 EPE29108.1 - 0.046 14.0 0.1 0.071 13.4 0.1 1.3 1 0 0 1 1 1 0 APOBEC1 SNAD4 PF18750.1 EPE29108.1 - 0.11 12.7 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 FAD_SOX PF18371.1 EPE29108.1 - 0.13 12.7 0.0 0.21 12.0 0.0 1.4 1 1 0 1 1 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Aminotran_4 PF01063.19 EPE29109.1 - 1.4e-27 97.0 0.0 2e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV BTB PF00651.31 EPE29112.1 - 0.0072 16.5 0.0 0.017 15.3 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain CAP PF00188.26 EPE29114.1 - 6.3e-19 69.1 3.4 3.5e-18 66.7 3.4 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_transf_20 PF00982.21 EPE29115.1 - 1.2e-164 548.5 0.2 1.6e-164 548.1 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EPE29115.1 - 1e-47 162.2 0.0 1.7e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Atrophin-1 PF03154.15 EPE29115.1 - 0.12 10.7 8.9 0.16 10.2 8.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family AAA PF00004.29 EPE29116.1 - 1.4e-11 44.9 0.1 1.9e-10 41.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RSN1_7TM PF02714.15 EPE29117.1 - 5.4e-81 271.9 22.6 8.3e-81 271.3 22.6 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EPE29117.1 - 7.7e-43 146.8 0.1 1.2e-42 146.2 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EPE29117.1 - 5.4e-40 136.7 1.5 2.3e-39 134.7 0.2 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport Anoctamin PF04547.12 EPE29117.1 - 0.0014 17.6 1.0 0.0029 16.5 1.0 1.4 1 0 0 1 1 1 1 Calcium-activated chloride channel F-box-like PF12937.7 EPE29117.1 - 0.05 13.5 0.1 0.05 13.5 0.1 2.7 3 0 0 3 3 3 0 F-box-like GATase PF00117.28 EPE29118.1 - 1.6e-09 37.8 0.0 2.3e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EPE29118.1 - 6e-05 22.9 0.6 0.0002 21.2 0.6 1.8 1 1 0 1 1 1 1 Peptidase C26 DUF4078 PF13300.6 EPE29118.1 - 0.13 12.6 0.6 0.2 12.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4078) ADH_zinc_N PF00107.26 EPE29120.1 - 2.3e-12 47.0 0.1 6.4e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE29120.1 - 1.9e-05 24.5 0.8 0.00017 21.4 0.3 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EPE29120.1 - 0.00014 22.9 0.0 0.0003 21.8 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase MAPEG PF01124.18 EPE29121.1 - 3.1e-17 62.7 0.2 3.8e-17 62.4 0.2 1.1 1 0 0 1 1 1 1 MAPEG family HET PF06985.11 EPE29122.1 - 4.1e-27 95.3 0.0 7.5e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 EPE29124.1 - 3.6e-74 250.2 0.0 4.7e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 EPE29124.1 - 1.2e-26 93.7 0.2 2e-26 93.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EPE29124.1 - 3.2e-22 79.3 0.0 5.4e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EPE29124.1 - 1e-11 45.4 0.0 3e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EPE29124.1 - 0.0016 18.7 0.0 0.0035 17.6 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain DUF4295 PF14128.6 EPE29124.1 - 0.059 13.2 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4295) KAR9 PF08580.10 EPE29125.1 - 4.9e-177 590.5 18.7 4.9e-177 590.5 18.7 2.0 2 0 0 2 2 2 1 Yeast cortical protein KAR9 THOC7 PF05615.13 EPE29125.1 - 0.15 12.4 5.8 3.1 8.1 5.8 2.9 1 1 0 1 1 1 0 Tho complex subunit 7 Prefoldin_2 PF01920.20 EPE29125.1 - 0.34 10.9 6.7 2.9 7.9 0.1 3.8 3 0 0 3 3 3 0 Prefoldin subunit MIOX PF05153.15 EPE29126.1 - 9.6e-126 418.4 0.9 1.3e-125 418.0 0.9 1.2 1 0 0 1 1 1 1 Myo-inositol oxygenase DUF1796 PF08795.10 EPE29126.1 - 0.011 15.7 0.6 0.017 15.1 0.6 1.2 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) HD PF01966.22 EPE29126.1 - 0.021 15.0 0.1 0.61 10.3 0.0 2.6 3 0 0 3 3 3 0 HD domain Cytochrom_C_2 PF01322.20 EPE29126.1 - 0.043 14.7 0.7 0.079 13.9 0.7 1.4 1 0 0 1 1 1 0 Cytochrome C' F-box-like PF12937.7 EPE29127.1 - 0.0026 17.6 1.3 0.0051 16.7 0.2 2.1 2 1 0 2 2 2 1 F-box-like Motilin_ghrelin PF04644.12 EPE29127.1 - 0.027 14.3 0.1 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 Motilin/ghrelin LRR_4 PF12799.7 EPE29127.1 - 8.3 7.0 9.4 8.1 7.0 0.4 4.2 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) AOX PF01786.17 EPE29129.1 - 3e-94 314.6 0.2 3.9e-94 314.2 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase DUF726 PF05277.12 EPE29130.1 - 4.6e-125 417.1 2.1 6.8e-125 416.5 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Fcf1 PF04900.12 EPE29131.1 - 2.6e-27 95.1 0.1 4.8e-27 94.3 0.1 1.4 1 0 0 1 1 1 1 Fcf1 RXT2_N PF08595.11 EPE29132.1 - 0.18 11.8 4.1 0.29 11.1 4.1 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal GUB_WAK_bind PF13947.6 EPE29132.1 - 0.21 12.3 0.9 0.56 11.0 0.2 1.9 2 0 0 2 2 2 0 Wall-associated receptor kinase galacturonan-binding zf-CCHC PF00098.23 EPE29133.1 - 0.00014 21.8 0.7 0.00014 21.8 0.7 4.9 5 0 0 5 5 5 2 Zinc knuckle SPATA24 PF15175.6 EPE29133.1 - 0.0048 16.8 0.8 0.015 15.2 0.8 1.8 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 zf-CCHC_3 PF13917.6 EPE29133.1 - 0.033 14.2 0.5 0.033 14.2 0.5 4.7 4 0 0 4 4 4 0 Zinc knuckle MCC-bdg_PDZ PF10506.9 EPE29133.1 - 0.18 11.8 11.9 0.025 14.6 3.8 2.7 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome zf-CCHC_4 PF14392.6 EPE29133.1 - 0.97 9.2 26.6 0.49 10.2 0.6 4.6 4 0 0 4 4 4 0 Zinc knuckle DUF3425 PF11905.8 EPE29134.1 - 8.6e-21 74.2 0.0 2e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.25 EPE29135.1 - 2e-21 76.3 0.0 9.5e-18 64.4 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE29135.1 - 3.6e-10 39.8 0.0 4.3e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE29135.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE29135.1 - 0.0011 18.2 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EPE29135.1 - 0.0015 18.1 0.0 0.0034 16.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.13 EPE29135.1 - 0.013 15.5 0.0 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family ADH_N PF08240.12 EPE29136.1 - 1.2e-27 95.9 1.4 1.4e-27 95.7 0.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE29136.1 - 5.2e-20 71.7 0.3 9.3e-20 70.9 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EPE29136.1 - 2.3e-07 30.5 0.0 0.0076 15.8 0.0 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EPE29136.1 - 0.003 16.9 0.9 0.0055 16.0 0.9 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EPE29136.1 - 0.0034 17.0 0.1 0.0061 16.1 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 EPE29136.1 - 0.008 17.2 0.0 0.017 16.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 EPE29136.1 - 0.077 12.9 0.5 0.13 12.1 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EPE29136.1 - 0.083 13.0 0.6 0.38 10.8 0.3 2.2 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 EPE29136.1 - 0.092 12.1 0.6 0.21 10.9 0.6 1.5 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.6 EPE29136.1 - 0.1 13.1 0.2 0.23 11.9 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding HI0933_like PF03486.14 EPE29136.1 - 0.12 11.1 0.5 0.18 10.5 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 EPE29136.1 - 0.15 11.1 0.2 0.2 10.7 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 EPE29136.1 - 0.15 11.4 0.1 0.28 10.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 EPE29139.1 - 3.2e-57 193.8 0.0 4e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE29139.1 - 1.2e-52 178.3 0.1 1.4e-52 178.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE29139.1 - 5.3e-13 49.3 0.7 1e-12 48.3 0.7 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE29139.1 - 3.7e-09 36.4 0.0 4.5e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 EPE29139.1 - 0.0069 16.4 0.1 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 EPE29139.1 - 0.073 13.5 0.1 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding CoA_transf_3 PF02515.17 EPE29139.1 - 0.1 11.7 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 CoA-transferase family III DEAD PF00270.29 EPE29141.1 - 6.9e-23 81.3 0.0 1.8e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE29141.1 - 1.7e-18 67.0 0.1 4.4e-15 56.0 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.10 EPE29141.1 - 1.9e-18 66.3 0.1 4.8e-18 65.0 0.1 1.7 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 EPE29141.1 - 2.8e-17 63.2 4.3 1.2e-16 61.2 4.3 2.2 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 EPE29141.1 - 7e-07 29.4 0.0 2.2e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit BioW PF03744.13 EPE29141.1 - 0.057 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase SecA_DEAD PF07517.14 EPE29141.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain TMF_TATA_bd PF12325.8 EPE29141.1 - 0.12 12.6 1.1 0.41 10.9 1.1 1.9 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding MFS_1 PF07690.16 EPE29142.1 - 7.8e-29 100.7 13.3 1.1e-28 100.1 13.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily LacY_symp PF01306.19 EPE29142.1 - 1.6 7.4 14.4 0.062 12.1 4.2 2.6 3 0 0 3 3 3 0 LacY proton/sugar symporter GPI-anchored PF10342.9 EPE29143.1 - 5e-18 65.6 0.3 5e-18 65.6 0.3 2.9 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family BES1_N PF05687.13 EPE29143.1 - 3 8.2 8.6 5.1 7.5 8.6 1.5 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal ABC_membrane PF00664.23 EPE29144.1 - 2.7e-73 247.0 40.7 2.2e-38 132.5 16.7 3.1 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EPE29144.1 - 5.2e-63 211.6 0.0 4.8e-31 108.1 0.0 3.1 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EPE29144.1 - 4.2e-12 46.0 5.6 0.0025 17.3 0.1 4.4 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EPE29144.1 - 3.7e-08 33.7 0.1 0.04 14.2 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EPE29144.1 - 1.2e-07 31.3 0.4 0.0014 18.3 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EPE29144.1 - 8.8e-07 29.0 0.8 0.025 14.5 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EPE29144.1 - 1.4e-06 28.8 0.6 0.044 14.2 0.1 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_15 PF13175.6 EPE29144.1 - 5.1e-06 26.4 0.0 0.08 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 EPE29144.1 - 2e-05 23.6 0.3 0.14 10.9 0.0 3.5 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 EPE29144.1 - 2.5e-05 24.1 0.0 0.34 10.6 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 EPE29144.1 - 5.9e-05 23.0 0.1 0.68 9.7 0.0 3.2 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EPE29144.1 - 0.00019 22.0 5.2 0.037 14.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 EPE29144.1 - 0.00055 19.6 0.3 1.2 8.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EPE29144.1 - 0.001 19.1 0.0 0.87 9.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EPE29144.1 - 0.0013 19.1 1.3 0.72 10.3 0.3 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EPE29144.1 - 0.0046 16.9 0.0 0.44 10.4 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain ATP-synt_ab PF00006.25 EPE29144.1 - 0.0046 16.6 0.0 3.5 7.2 0.0 2.6 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 EPE29144.1 - 0.0057 17.2 0.1 1.8 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 EPE29144.1 - 0.006 16.4 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EPE29144.1 - 0.0063 16.0 0.0 0.86 9.1 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EPE29144.1 - 0.0076 16.5 0.0 5.3 7.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EPE29144.1 - 0.019 15.0 0.1 26 4.8 0.0 3.6 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 EPE29144.1 - 0.032 13.9 0.0 6.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 EPE29144.1 - 0.038 14.2 4.2 2.7 8.3 0.3 4.0 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EPE29144.1 - 0.045 13.9 0.0 6.6 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EPE29144.1 - 0.095 11.9 0.1 5.5 6.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 EPE29144.1 - 0.12 12.8 0.1 32 5.0 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.6 EPE29144.1 - 0.12 12.0 0.4 15 5.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 EPE29144.1 - 0.13 12.3 0.7 0.46 10.5 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain PI3K_1B_p101 PF10486.9 EPE29144.1 - 0.19 9.4 2.7 0.53 8.0 0.0 2.0 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TRP PF06011.12 EPE29145.1 - 7.3e-139 463.2 21.2 9.6e-139 462.8 21.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EPE29145.1 - 9.5e-39 132.9 3.4 9.5e-39 132.9 3.4 1.8 2 0 0 2 2 2 1 ML-like domain CRT10 PF08728.10 EPE29147.1 - 3.6e-13 48.6 0.0 1.3e-06 26.9 0.0 2.2 2 0 0 2 2 2 2 CRT10 Ammonium_transp PF00909.21 EPE29148.1 - 5.4e-116 387.6 29.4 6.3e-116 387.4 29.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Tox-SHH PF15652.6 EPE29150.1 - 0.072 14.0 0.0 0.079 13.9 0.0 1.1 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature Sugar_tr PF00083.24 EPE29153.1 - 5.7e-125 417.7 25.6 6.6e-125 417.5 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE29153.1 - 4.4e-16 58.8 31.3 1.7e-10 40.4 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Kelch_6 PF13964.6 EPE29156.1 - 0.0057 16.9 1.5 3 8.3 0.0 3.8 5 0 0 5 5 5 2 Kelch motif HpcH_HpaI PF03328.14 EPE29157.1 - 0.075 12.2 0.0 0.087 12.0 0.0 1.1 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family HLH PF00010.26 EPE29158.1 - 1.3e-14 53.8 0.0 3.2e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Med28 PF11594.8 EPE29158.1 - 0.25 11.4 2.9 0.99 9.5 0.0 2.7 3 0 0 3 3 3 0 Mediator complex subunit 28 AAA_23 PF13476.6 EPE29158.1 - 4.3 7.8 7.5 11 6.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain Pcc1 PF09341.10 EPE29159.1 - 3.7e-32 110.3 0.4 4.7e-32 110.0 0.4 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.6 EPE29160.1 - 1.7e-41 142.0 0.0 8e-39 133.3 0.0 2.7 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EPE29160.1 - 4.3e-16 58.9 0.0 8.7e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EPE29160.1 - 2.9e-05 23.7 0.0 5.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EPE29160.1 - 0.21 11.3 0.1 0.52 10.0 0.1 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) 14-3-3 PF00244.20 EPE29161.1 - 2.9e-107 357.3 6.1 3.4e-107 357.0 6.1 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 EPE29161.1 - 0.14 12.7 2.8 0.75 10.3 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Hamartin PF04388.12 EPE29162.1 - 1.3 7.6 2.7 1.5 7.4 2.7 1.0 1 0 0 1 1 1 0 Hamartin protein IATP PF04568.12 EPE29163.1 - 4.7e-27 94.3 1.4 5.4e-27 94.1 1.4 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP PEP-utilisers_N PF05524.13 EPE29163.1 - 0.064 13.4 0.5 0.097 12.8 0.2 1.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Atg14 PF10186.9 EPE29163.1 - 0.073 12.1 0.8 0.094 11.8 0.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF489 PF04356.12 EPE29163.1 - 0.086 12.8 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF1699 PF08004.11 EPE29163.1 - 0.092 12.4 0.2 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) Nsp1_C PF05064.13 EPE29164.1 - 2.7e-39 133.6 3.0 6.1e-39 132.4 3.0 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EPE29164.1 - 0.00013 22.8 28.5 0.00013 22.8 28.5 6.0 1 1 4 5 5 3 3 Nucleoporin FG repeat region DUF812 PF05667.11 EPE29164.1 - 0.03 13.2 3.9 0.044 12.7 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TACC_C PF05010.14 EPE29164.1 - 0.08 12.7 4.9 0.042 13.6 1.9 1.8 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal WXG100 PF06013.12 EPE29164.1 - 0.083 13.1 3.4 0.079 13.2 0.5 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG KxDL PF10241.9 EPE29164.1 - 0.17 12.1 5.3 11 6.4 0.4 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein BRE1 PF08647.11 EPE29164.1 - 0.41 10.8 7.9 0.41 10.7 2.1 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase AAA_13 PF13166.6 EPE29164.1 - 0.61 8.7 7.4 1.1 7.8 0.7 2.0 1 1 1 2 2 2 0 AAA domain ERM PF00769.19 EPE29164.1 - 0.68 9.7 5.8 1.1 9.1 5.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HIP1_clath_bdg PF16515.5 EPE29164.1 - 0.79 10.4 7.9 6 7.5 3.2 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3450 PF11932.8 EPE29164.1 - 0.8 9.0 12.8 0.16 11.2 5.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) IFT57 PF10498.9 EPE29164.1 - 0.96 8.3 8.7 0.2 10.6 3.1 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF948 PF06103.11 EPE29164.1 - 1.1 9.6 2.7 3.5 7.9 0.2 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 EPE29164.1 - 1.1 9.3 8.5 2.2 8.3 0.9 2.6 2 1 0 2 2 2 0 Laminin Domain II CK2S PF15011.6 EPE29164.1 - 1.5 8.7 5.5 2.8 7.8 1.8 2.3 2 0 0 2 2 2 0 Casein Kinase 2 substrate BORCS7 PF16088.5 EPE29164.1 - 2 8.7 5.3 16 5.8 0.7 2.5 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 DUF4407 PF14362.6 EPE29164.1 - 2.4 7.5 4.5 3.8 6.8 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 EPE29164.1 - 3.4 7.0 8.5 2 7.7 4.3 2.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 EPE29164.1 - 3.9 5.5 9.5 2.7 6.1 3.0 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF4349 PF14257.6 EPE29164.1 - 4.1 6.8 6.2 1.8 7.9 2.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF1664 PF07889.12 EPE29164.1 - 5.4 7.1 6.8 14 5.8 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 EPE29164.1 - 7 4.5 5.7 11 3.9 0.5 2.0 2 0 0 2 2 2 0 Prominin DHR10 PF18595.1 EPE29164.1 - 7.1 6.7 11.2 1.9 8.6 2.8 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF5102 PF17104.5 EPE29165.1 - 4.8e-115 384.6 3.6 9.8e-115 383.5 3.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) RRM_1 PF00076.22 EPE29166.1 - 1.7e-43 146.3 0.0 8.7e-17 60.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EPE29166.1 - 1.1e-05 25.3 0.1 0.0018 18.3 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EPE29166.1 - 3.3e-05 23.8 0.0 0.0014 18.6 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 EPE29166.1 - 4.8e-05 23.1 0.0 0.066 13.1 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EPE29166.1 - 0.00095 19.2 0.2 0.058 13.5 0.0 2.8 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 EPE29166.1 - 0.0024 17.5 0.0 0.023 14.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HAMP PF00672.25 EPE29167.1 - 1.9e-42 143.4 12.9 3.1e-08 33.9 0.0 7.3 6 0 0 6 6 6 5 HAMP domain HATPase_c PF02518.26 EPE29167.1 - 2.1e-30 105.5 0.2 9.8e-30 103.3 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPE29167.1 - 1.2e-25 89.9 1.2 5.3e-25 87.8 0.6 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EPE29167.1 - 2.4e-17 62.7 5.2 2.9e-17 62.4 0.6 3.6 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain DUF4279 PF14106.6 EPE29167.1 - 4.9e-05 23.5 0.0 11 6.3 0.0 5.2 5 0 0 5 5 5 1 Domain of unknown function (DUF4279) DUF948 PF06103.11 EPE29167.1 - 0.0052 17.0 43.7 0.32 11.3 1.5 8.6 4 2 3 7 7 6 2 Bacterial protein of unknown function (DUF948) GhoS PF11080.8 EPE29167.1 - 0.0085 16.0 1.1 0.5 10.4 0.1 3.3 2 0 0 2 2 2 1 Endoribonuclease GhoS ZapD PF07072.11 EPE29167.1 - 0.014 15.1 3.4 0.017 14.8 1.3 2.3 2 0 0 2 2 2 0 Cell division protein Fib_alpha PF08702.10 EPE29167.1 - 0.039 14.1 33.5 0.086 13.0 3.2 6.7 6 1 0 6 6 6 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 EPE29167.1 - 0.057 13.6 26.7 6.3 7.1 8.0 6.9 5 2 3 8 8 8 0 TATA element modulatory factor 1 TATA binding DUF3829 PF12889.7 EPE29167.1 - 0.2 11.1 12.5 2.3 7.6 0.1 4.6 3 2 0 4 4 4 0 Protein of unknown function (DUF3829) Tho2 PF11262.8 EPE29167.1 - 0.26 10.5 2.8 0.74 9.0 2.8 1.7 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PilJ PF13675.6 EPE29167.1 - 1.3 9.1 12.2 49 4.0 0.3 5.5 2 1 4 6 6 6 0 Type IV pili methyl-accepting chemotaxis transducer N-term Rotamase PF00639.21 EPE29167.1 - 4.1 8.4 12.3 12 6.9 0.7 4.9 3 2 1 5 5 4 0 PPIC-type PPIASE domain MitMem_reg PF13012.6 EPE29167.1 - 7.2 7.1 19.0 0.35 11.3 0.6 4.8 1 1 1 2 2 1 0 Maintenance of mitochondrial structure and function Membr_traf_MHD PF10540.9 EPE29168.1 - 1.4e-21 77.3 0.9 9.9e-10 38.8 0.0 2.8 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EPE29168.1 - 1e-16 61.0 0.0 2.3e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 EPE29168.1 - 2.4e-08 33.0 0.1 6.6e-08 31.6 0.1 1.7 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) TipAS PF07739.13 EPE29168.1 - 1.8 9.1 4.8 3.6 8.2 0.0 3.2 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain FAM176 PF14851.6 EPE29169.1 - 0.05 13.3 0.2 0.12 12.0 0.2 1.6 1 0 0 1 1 1 0 FAM176 family zf-C2H2 PF00096.26 EPE29170.1 - 0.0029 18.0 3.7 0.44 11.1 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE29170.1 - 0.02 15.7 2.5 8.2 7.6 0.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Sugar_tr PF00083.24 EPE29171.1 - 8.5e-41 140.3 13.1 1.2e-30 106.8 0.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EPE29171.1 - 1.3e-07 30.9 31.6 9.8e-06 24.7 9.5 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily PCNA_N PF00705.18 EPE29172.1 - 3.1e-54 182.0 4.1 3.1e-54 182.0 4.1 1.8 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EPE29172.1 - 1.2e-48 164.5 0.1 1.5e-47 161.0 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EPE29172.1 - 8.9e-08 31.9 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 EPE29172.1 - 2.9e-05 23.3 0.4 0.0013 17.9 0.4 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 EPE29172.1 - 0.00023 20.4 0.1 0.0017 17.6 0.1 2.0 2 0 0 2 2 2 1 Hus1-like protein DUF1480 PF07351.13 EPE29172.1 - 0.015 15.6 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) AMA-1 PF02430.15 EPE29172.1 - 0.066 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Apical membrane antigen 1 DNA_pol3_beta_3 PF02768.15 EPE29172.1 - 0.12 12.2 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain Phos_pyr_kin PF08543.12 EPE29173.1 - 4.5e-11 42.6 0.0 2e-10 40.5 0.0 1.9 1 1 1 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EPE29173.1 - 3e-06 26.8 0.1 7e-06 25.5 0.1 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase dUTPase PF00692.19 EPE29174.1 - 8e-47 158.1 0.0 1.1e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 dUTPase SSXRD PF09514.10 EPE29175.1 - 0.023 14.3 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 SSXRD motif TUSC2 PF15000.6 EPE29176.1 - 0.056 13.7 0.3 0.13 12.6 0.3 1.6 1 0 0 1 1 1 0 Tumour suppressor candidate 2 C5HCH PF17982.1 EPE29176.1 - 0.16 12.1 0.1 0.37 11.0 0.1 1.5 1 0 0 1 1 1 0 NSD Cys-His rich domain Hydrolase_4 PF12146.8 EPE29178.1 - 5.2e-16 58.6 0.0 8e-15 54.7 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE29178.1 - 1.3e-14 54.4 0.1 4.2e-14 52.8 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE29178.1 - 1.7e-13 51.7 0.7 3.2e-13 50.8 0.7 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EPE29178.1 - 0.0032 17.2 0.0 0.35 10.6 0.0 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family DLH PF01738.18 EPE29178.1 - 0.0055 16.3 0.0 2.8 7.5 0.0 2.7 2 1 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.13 EPE29178.1 - 0.093 12.4 0.8 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) zf-C2H2 PF00096.26 EPE29179.1 - 1.8e-06 28.1 24.0 0.00026 21.2 0.8 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE29179.1 - 0.0024 18.5 1.0 0.0024 18.5 1.0 5.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EPE29179.1 - 1.9 8.6 8.2 0.2 11.7 2.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger DUF202 PF02656.15 EPE29180.1 - 0.0023 18.3 6.3 0.0078 16.6 6.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF202) Zn_clus PF00172.18 EPE29181.1 - 2.8e-07 30.6 8.8 4.3e-07 29.9 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-bind_6 PF13921.6 EPE29185.1 - 0.00014 22.0 0.0 0.0003 21.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain IFT57 PF10498.9 EPE29185.1 - 0.011 14.7 0.3 0.016 14.2 0.3 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Myb_DNA-binding PF00249.31 EPE29185.1 - 0.027 14.6 0.7 0.058 13.6 0.7 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Rotamase_3 PF13616.6 EPE29185.1 - 0.13 12.8 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain Methyltransf_11 PF08241.12 EPE29186.1 - 7.4e-12 45.8 0.2 2.1e-11 44.3 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE29186.1 - 1.5e-11 44.8 0.1 3.4e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE29186.1 - 8.4e-07 29.7 0.0 1.5e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE29186.1 - 3.2e-06 27.0 0.0 5.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE29186.1 - 1.2e-05 24.8 0.0 1.6e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EPE29186.1 - 0.005 16.7 0.0 0.0077 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EPE29186.1 - 0.0094 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Spermine_synth PF01564.17 EPE29186.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase domain DREV PF05219.12 EPE29186.1 - 0.19 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase APH PF01636.23 EPE29187.1 - 5e-16 59.3 0.0 8.2e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE29187.1 - 1e-05 25.3 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase FYVE PF01363.21 EPE29189.1 - 0.016 15.3 1.1 0.032 14.3 1.1 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-B_box PF00643.24 EPE29189.1 - 0.017 15.2 6.7 0.032 14.4 6.7 1.4 1 0 0 1 1 1 0 B-box zinc finger C1_2 PF03107.16 EPE29189.1 - 0.055 13.8 5.9 0.12 12.7 5.9 1.5 1 0 0 1 1 1 0 C1 domain C1_4 PF07975.12 EPE29189.1 - 0.098 12.9 3.7 0.25 11.6 3.7 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain IBR PF01485.21 EPE29189.1 - 0.2 11.9 4.9 0.44 10.8 4.9 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Zn_ribbon_17 PF17120.5 EPE29189.1 - 0.42 10.3 6.1 0.73 9.5 6.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type NHase_alpha PF02979.16 EPE29191.1 - 0.14 11.5 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain CpeS PF09367.10 EPE29193.1 - 0.028 14.4 0.1 0.035 14.0 0.1 1.1 1 0 0 1 1 1 0 CpeS-like protein FAM47 PF14642.6 EPE29193.1 - 0.17 11.4 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 FAM47 family Lactamase_B_3 PF13483.6 EPE29195.1 - 1.2e-07 31.8 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EPE29195.1 - 7.2e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HA2 PF04408.23 EPE29196.1 - 2.2e-21 76.2 0.5 2.3e-20 72.9 0.0 2.7 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EPE29196.1 - 5.3e-18 65.2 0.1 3.4e-17 62.6 0.0 2.4 3 0 0 3 3 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EPE29196.1 - 5.4e-13 49.2 0.0 1.4e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPE29196.1 - 2.8e-08 33.8 0.1 5.3e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 EPE29196.1 - 4.3e-05 22.9 0.0 9.1e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EPE29196.1 - 0.0001 22.6 0.1 0.00027 21.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPE29196.1 - 0.00023 20.9 0.0 0.00051 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EPE29196.1 - 0.0006 20.1 0.4 0.0029 17.9 0.4 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EPE29196.1 - 0.0039 17.2 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EPE29196.1 - 0.0057 15.7 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 EPE29196.1 - 0.021 14.5 0.5 0.063 12.9 0.5 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 EPE29196.1 - 0.022 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 EPE29196.1 - 0.042 13.9 0.5 0.33 11.0 0.5 2.2 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EPE29196.1 - 0.044 13.3 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Flavi_DEAD PF07652.14 EPE29196.1 - 0.044 13.7 0.1 0.086 12.8 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_16 PF13191.6 EPE29196.1 - 0.08 13.3 0.1 0.23 11.8 0.0 1.8 2 0 0 2 2 1 0 AAA ATPase domain ABC_tran PF00005.27 EPE29196.1 - 0.092 13.3 0.1 0.42 11.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 EPE29196.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EPE29196.1 - 0.11 12.0 0.0 0.29 10.5 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 EPE29196.1 - 0.12 12.6 0.6 0.36 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EPE29196.1 - 0.15 12.0 0.1 0.86 9.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain WD40 PF00400.32 EPE29197.1 - 5.7e-16 58.6 8.2 0.00097 19.9 0.3 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE29197.1 - 3.1e-05 24.2 0.3 0.015 15.6 0.1 3.7 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPE29197.1 - 4.1e-05 22.4 1.9 0.00047 18.9 1.5 2.6 2 1 1 3 3 3 1 Nucleoporin Nup120/160 YtxC PF08812.11 EPE29198.1 - 0.081 12.5 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 YtxC-like family HTH_DeoR PF08220.12 EPE29198.1 - 0.21 11.4 0.1 2.7 7.8 0.1 2.2 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain Hep_59 PF07052.11 EPE29199.1 - 1.2e-16 61.4 0.1 9.8e-16 58.4 0.0 2.5 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 ResIII PF04851.15 EPE29200.1 - 2.4e-23 83.0 0.0 5.5e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EPE29200.1 - 4.9e-21 75.1 0.2 1.5e-20 73.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPE29200.1 - 4.2e-15 55.9 0.0 1.9e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EPE29200.1 - 6.4e-05 22.7 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 EPE29200.1 - 0.016 15.5 0.0 0.1 12.9 0.0 2.3 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 EPE29200.1 - 0.044 13.0 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TT_ORF2 PF02957.15 EPE29200.1 - 1.7 9.6 6.5 8.1 7.4 0.0 3.7 3 0 0 3 3 3 0 TT viral ORF2 DUF846 PF05832.12 EPE29201.1 - 2.8e-33 114.9 5.4 4.1e-31 107.9 5.4 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) AMP-binding PF00501.28 EPE29202.1 - 2.2e-71 240.7 0.0 2.6e-71 240.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE29202.1 - 9.7e-12 45.7 0.0 2.1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain F-box PF00646.33 EPE29204.1 - 1.1e-07 31.6 1.2 1.9e-07 30.8 1.2 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPE29204.1 - 7.3e-07 29.0 0.9 1.5e-06 28.0 0.9 1.6 1 0 0 1 1 1 1 F-box-like Aldedh PF00171.22 EPE29205.1 - 4e-136 454.2 0.4 4.7e-136 454.0 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PsbH PF00737.20 EPE29205.1 - 0.043 13.5 0.0 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein PsaN PF05479.11 EPE29205.1 - 0.053 13.7 0.5 0.78 9.9 0.0 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) LuxC PF05893.14 EPE29205.1 - 0.079 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Sec20 PF03908.13 EPE29207.1 - 1.4e-18 66.6 0.4 3.7e-18 65.2 0.4 1.8 1 0 0 1 1 1 1 Sec20 TMF_TATA_bd PF12325.8 EPE29207.1 - 0.13 12.5 15.4 0.67 10.2 0.3 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding MRP_L53 PF10780.9 EPE29208.1 - 2.6e-19 69.1 1.4 4.2e-19 68.5 1.4 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Pyrophosphatase PF00719.19 EPE29209.1 - 1.3e-58 197.3 0.1 1.7e-58 197.0 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Dus PF01207.17 EPE29210.1 - 4.3e-44 150.9 0.1 1.1e-43 149.6 0.1 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) FCP1_C PF09309.10 EPE29210.1 - 0.067 13.1 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 FCP1, C-terminal TMP-TENI PF02581.17 EPE29210.1 - 0.11 11.8 0.0 0.33 10.3 0.0 1.8 1 0 0 1 1 1 0 Thiamine monophosphate synthase Ctr PF04145.15 EPE29211.1 - 3.7e-39 134.7 0.8 4.7e-39 134.4 0.8 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Rep_fac_C PF08542.11 EPE29212.1 - 5.1e-21 74.9 0.0 9.7e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EPE29212.1 - 1.8e-16 60.8 0.0 4.6e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EPE29212.1 - 1.1e-13 51.3 0.1 3.4e-12 46.4 0.0 2.5 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EPE29212.1 - 6.5e-09 36.0 0.0 1.4e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 EPE29212.1 - 4.6e-06 26.5 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 EPE29212.1 - 5.4e-06 26.2 0.1 7.9e-05 22.5 0.0 2.8 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EPE29212.1 - 1.8e-05 25.2 0.0 0.0006 20.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EPE29212.1 - 3e-05 24.3 0.0 0.00029 21.1 0.0 2.5 2 2 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 EPE29212.1 - 3.6e-05 24.0 0.0 0.0001 22.5 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 EPE29212.1 - 4.3e-05 23.4 0.0 7.2e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EPE29212.1 - 0.00058 19.9 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EPE29212.1 - 0.00084 18.8 0.0 0.035 13.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EPE29212.1 - 0.00096 18.4 0.0 0.0027 16.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EPE29212.1 - 0.0018 18.3 0.1 0.015 15.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EPE29212.1 - 0.0029 17.4 0.0 0.011 15.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPE29212.1 - 0.0038 17.6 0.1 0.031 14.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EPE29212.1 - 0.004 16.9 0.0 0.0095 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EPE29212.1 - 0.0055 16.2 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 EPE29212.1 - 0.0086 16.3 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EPE29212.1 - 0.009 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 EPE29212.1 - 0.017 15.6 0.0 0.05 14.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EPE29212.1 - 0.029 14.4 0.0 0.081 12.9 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 EPE29212.1 - 0.08 13.3 0.0 0.27 11.6 0.0 1.9 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.12 EPE29212.1 - 0.09 12.7 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_3 PF07726.11 EPE29212.1 - 0.11 12.4 0.0 0.55 10.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EPE29212.1 - 0.12 11.8 0.0 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Pkinase PF00069.25 EPE29213.1 - 3.6e-29 101.9 0.0 1.2e-15 57.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE29213.1 - 4.7e-05 22.8 0.0 0.0018 17.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2417 PF10329.9 EPE29214.1 - 4.4e-88 294.7 0.3 6.4e-88 294.2 0.3 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) GWT1 PF06423.12 EPE29214.1 - 0.026 14.7 1.0 5.7 7.0 0.0 2.6 3 0 0 3 3 3 0 GWT1 Polyoma_agno PF01736.16 EPE29214.1 - 0.084 12.6 0.0 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Polyomavirus agnoprotein ABC2_membrane_3 PF12698.7 EPE29214.1 - 0.37 9.9 15.2 0.07 12.2 11.8 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4267 PF14087.6 EPE29214.1 - 2 8.5 5.1 0.83 9.7 2.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) DUF2070 PF09843.9 EPE29214.1 - 5.4 5.2 10.9 7.7 4.7 10.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Abhydrolase_6 PF12697.7 EPE29215.1 - 2.2e-21 77.5 1.2 3.9e-21 76.7 0.2 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE29215.1 - 2e-06 27.6 0.0 7.5e-06 25.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE29215.1 - 6.6e-06 25.6 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EPE29215.1 - 0.0001 22.5 0.0 0.00029 21.0 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain DUF1746 PF08508.10 EPE29216.1 - 9.3e-46 154.9 1.2 1.3e-45 154.4 1.2 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RTC_insert PF05189.13 EPE29217.1 - 1.8e-29 102.2 0.2 3.1e-29 101.5 0.2 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 EPE29217.1 - 8.4e-27 93.8 0.2 1e-26 93.5 0.2 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase PWWP PF00855.17 EPE29218.1 - 3.1e-12 46.8 0.8 1.3e-10 41.5 0.8 2.8 1 1 0 1 1 1 1 PWWP domain Med26 PF08711.11 EPE29218.1 - 0.0058 16.6 0.2 0.015 15.3 0.2 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain RsbU_N PF08673.10 EPE29218.1 - 0.13 12.4 1.0 0.72 10.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain TssC PF17541.2 EPE29218.1 - 0.46 9.2 5.7 0.093 11.5 1.6 1.7 2 0 0 2 2 2 0 Type VI secretion system, TssC, VipB LsmAD PF06741.13 EPE29218.1 - 0.95 10.1 5.0 4 8.1 5.0 2.1 1 0 0 1 1 1 0 LsmAD domain Sec63 PF02889.16 EPE29219.1 - 4.8e-166 550.3 0.1 6.7e-92 307.3 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EPE29219.1 - 2.2e-48 164.3 0.0 7e-27 94.3 0.0 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EPE29219.1 - 1.3e-32 112.3 0.2 3.9e-32 110.7 0.2 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EPE29219.1 - 1.7e-25 90.0 0.0 1.1e-13 51.5 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EPE29219.1 - 5.5e-11 42.8 0.0 2.8e-08 34.1 0.0 3.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EPE29219.1 - 5.8e-10 39.6 0.3 0.00024 21.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EPE29219.1 - 7.5e-07 29.0 0.0 0.0031 17.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 EPE29219.1 - 0.00018 20.7 0.0 0.47 9.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 EPE29219.1 - 0.0029 17.1 0.0 0.043 13.3 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.6 EPE29219.1 - 0.062 13.6 0.0 26 5.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain TFIIE_alpha PF02002.17 EPE29219.1 - 0.085 12.7 0.1 1.8 8.5 0.0 3.1 3 0 0 3 3 3 0 TFIIE alpha subunit DUF1548 PF07579.11 EPE29220.1 - 0.11 12.9 0.1 0.34 11.3 0.1 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) tRNA-synt_2d PF01409.20 EPE29221.1 - 2.6e-86 289.1 0.0 3.6e-86 288.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EPE29221.1 - 3.4e-17 62.5 0.8 8.3e-17 61.2 0.8 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EPE29221.1 - 2.4e-06 27.2 0.0 0.0027 17.2 0.0 3.1 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 EPE29221.1 - 7.2e-06 25.9 1.4 2.3e-05 24.3 1.4 2.0 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 EPE29221.1 - 8.1e-05 21.8 0.2 0.0018 17.4 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) DUF1938 PF09153.10 EPE29221.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) CPSase_L_D2 PF02786.17 EPE29222.1 - 2.2e-83 278.9 0.0 3.4e-83 278.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EPE29222.1 - 1.7e-39 134.9 0.0 5.4e-39 133.3 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EPE29222.1 - 4.2e-08 33.0 0.0 7.4e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EPE29222.1 - 4e-07 29.8 0.0 7.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EPE29222.1 - 0.00018 21.3 0.0 0.00059 19.6 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 EPE29222.1 - 0.0085 15.6 0.1 0.026 14.0 0.1 1.8 1 1 1 2 2 2 1 ATP-grasp domain HTH_AsnC-type PF13404.6 EPE29222.1 - 0.022 14.6 0.1 0.062 13.1 0.1 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain UBA_6 PF18039.1 EPE29222.1 - 0.11 12.4 0.0 0.41 10.6 0.0 2.0 1 1 1 2 2 2 0 UBA-like domain CPSase_L_D2 PF02786.17 EPE29223.1 - 2.2e-24 86.1 0.0 4.3e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 EPE29223.1 - 9.6e-10 38.3 0.0 3.6e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EPE29223.1 - 4.9e-09 36.0 0.1 9.9e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EPE29223.1 - 4.8e-05 23.1 0.0 0.00019 21.2 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.6 EPE29223.1 - 0.0066 16.1 0.0 0.018 14.6 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EPE29223.1 - 0.0089 15.8 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 EPE29223.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain NPL4 PF05021.15 EPE29224.1 - 4e-137 456.6 0.0 5.2e-137 456.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EPE29224.1 - 8.2e-67 223.9 0.1 1.4e-66 223.1 0.1 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EPE29224.1 - 0.00011 22.6 0.0 0.00029 21.3 0.0 1.7 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Sec66 PF09802.9 EPE29225.1 - 4.1e-81 270.9 0.1 5.1e-81 270.6 0.1 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 EPE29225.1 - 0.031 14.3 0.2 0.074 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) Cas_Csa4 PF09703.10 EPE29225.1 - 0.069 12.5 0.1 0.087 12.1 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) ORC3_N PF07034.11 EPE29227.1 - 3.4e-40 138.2 2.2 2.6e-24 86.0 2.3 2.3 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 EPE29227.1 - 1.4e-22 80.3 2.2 5.7e-12 45.9 0.0 2.9 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal PPR_2 PF13041.6 EPE29228.1 - 5.9e-08 32.8 4.1 0.098 12.9 0.0 7.5 9 0 0 9 9 9 2 PPR repeat family PPR PF01535.20 EPE29228.1 - 0.019 15.2 9.1 5.3 7.5 0.1 6.1 7 0 0 7 7 7 0 PPR repeat CEP209_CC5 PF16574.5 EPE29228.1 - 0.041 14.0 0.8 0.095 12.9 0.8 1.5 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 CoA_binding_2 PF13380.6 EPE29228.1 - 0.045 14.2 0.1 30 5.2 0.0 3.4 3 1 1 4 4 4 0 CoA binding domain TFIIS_M PF07500.14 EPE29228.1 - 0.51 10.8 3.5 0.37 11.3 0.4 2.4 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS), central domain Adaptin_binding PF10199.9 EPE29228.1 - 0.72 10.5 5.5 4.8 7.8 0.3 2.9 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 PPR_1 PF12854.7 EPE29228.1 - 0.85 9.4 4.9 14 5.5 0.1 4.0 5 0 0 5 5 5 0 PPR repeat DUF4187 PF13821.6 EPE29229.1 - 2e-21 75.5 0.8 4.7e-21 74.3 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EPE29229.1 - 2e-05 24.4 12.8 0.00011 22.0 12.8 2.1 1 1 0 1 1 1 1 G-patch domain CAP_GLY PF01302.25 EPE29230.1 - 5.8e-16 58.3 0.5 5.8e-16 58.3 0.5 2.0 2 0 0 2 2 1 1 CAP-Gly domain NPV_P10 PF05531.12 EPE29230.1 - 0.00015 22.2 2.1 0.084 13.3 0.8 2.8 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Fez1 PF06818.15 EPE29230.1 - 0.0032 18.0 24.0 0.02 15.4 9.7 3.2 3 0 0 3 3 3 1 Fez1 Uso1_p115_C PF04871.13 EPE29230.1 - 0.029 14.8 22.3 0.022 15.1 4.6 3.8 2 1 2 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF948 PF06103.11 EPE29230.1 - 0.062 13.6 2.7 0.14 12.4 0.5 2.6 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) Med4 PF10018.9 EPE29230.1 - 0.095 12.4 0.1 0.095 12.4 0.1 3.0 3 1 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 SPOUT_MTase_2 PF14419.6 EPE29230.1 - 0.17 11.2 1.4 0.32 10.3 0.1 1.9 2 0 0 2 2 2 0 AF2226-like SPOUT RNA Methylase fused to THUMP CLIP1_ZNF PF16641.5 EPE29230.1 - 0.18 11.7 10.3 1.2 9.0 1.7 2.4 2 0 0 2 2 2 0 CLIP1 zinc knuckle Baculo_PEP_C PF04513.12 EPE29230.1 - 0.32 11.0 1.0 8.6 6.4 0.6 2.6 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 EPE29230.1 - 0.42 9.4 24.3 0.35 9.7 7.6 3.4 2 1 0 3 3 3 0 Spc7 kinetochore protein AAA_13 PF13166.6 EPE29230.1 - 0.51 8.9 12.1 0.022 13.4 4.3 2.2 1 1 2 3 3 3 0 AAA domain MCPsignal PF00015.21 EPE29230.1 - 0.92 9.3 6.5 5.1 6.9 0.9 2.7 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-CCHC_4 PF14392.6 EPE29230.1 - 1.2 9.0 4.7 13 5.6 0.7 2.3 2 0 0 2 2 2 0 Zinc knuckle LXG PF04740.12 EPE29230.1 - 1.3 8.7 4.2 12 5.6 3.3 2.6 1 1 1 2 2 2 0 LXG domain of WXG superfamily HrpB7 PF09486.10 EPE29230.1 - 1.3 9.4 27.0 7.9 6.8 0.4 3.5 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF1640 PF07798.11 EPE29230.1 - 1.6 8.7 11.1 1.3 9.0 5.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) TMPIT PF07851.13 EPE29230.1 - 1.8 7.7 2.4 14 4.8 0.4 2.4 2 0 0 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 EPE29230.1 - 2.7 8.0 9.5 0.75 9.8 1.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF241 PF03087.14 EPE29230.1 - 2.9 7.7 10.7 0.41 10.4 5.0 2.4 2 1 0 2 2 2 0 Arabidopsis protein of unknown function FAM76 PF16046.5 EPE29230.1 - 4.5 6.5 8.1 7.6 5.8 0.0 2.9 2 1 0 3 3 3 0 FAM76 protein BLOC1_2 PF10046.9 EPE29230.1 - 5.2 7.4 11.8 0.1 12.9 1.5 2.9 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Helo_like_N PF17111.5 EPE29230.1 - 8.4 5.7 6.9 6.8 6.0 1.5 3.1 3 1 0 3 3 3 0 Fungal N-terminal domain of STAND proteins DUF812 PF05667.11 EPE29230.1 - 9.5 5.0 22.9 0.066 12.1 10.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Sec2p PF06428.11 EPE29230.1 - 9.9 6.2 15.7 2.2 8.3 0.5 3.8 3 1 0 3 3 3 0 GDP/GTP exchange factor Sec2p PITH PF06201.13 EPE29231.1 - 4.2e-39 134.2 0.0 6.9e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EPE29231.1 - 4.7e-16 58.6 0.0 8.3e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EPE29231.1 - 0.00077 18.9 0.1 0.0065 15.9 0.1 2.0 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EPE29231.1 - 0.025 14.9 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 EPE29231.1 - 0.061 13.8 0.1 0.39 11.2 0.1 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain NIF PF03031.18 EPE29231.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Pkinase PF00069.25 EPE29233.1 - 3.1e-06 26.8 0.0 1.4e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE29233.1 - 0.00047 19.5 0.0 0.024 13.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EPE29233.1 - 0.0045 17.0 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EPE29233.1 - 0.087 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase AICARFT_IMPCHas PF01808.18 EPE29234.1 - 3.5e-90 302.5 0.0 4.7e-90 302.0 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EPE29234.1 - 1.6e-23 82.7 0.1 2.8e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 MGS-like domain DUF3464 PF11947.8 EPE29236.1 - 0.24 11.2 1.0 0.52 10.0 0.3 1.9 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF1772 PF08592.11 EPE29236.1 - 2.1 8.7 6.0 2.9 8.2 5.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF202 PF02656.15 EPE29236.1 - 2.2 8.8 7.4 1.2e+02 3.2 2.4 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF2700 PF10912.8 EPE29236.1 - 3.5 7.6 6.6 3 7.9 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2700) PhoR PF11808.8 EPE29236.1 - 8.7 6.8 7.1 18 5.8 0.0 3.4 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR GpcrRhopsn4 PF10192.9 EPE29236.1 - 8.8 5.6 9.7 0.34 10.3 0.3 2.4 2 1 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain MPC PF03650.13 EPE29237.1 - 5.9e-36 123.0 0.0 7.6e-36 122.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers LSM PF01423.22 EPE29238.1 - 1.9e-18 65.9 0.0 2.6e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.21 EPE29239.1 - 3.8e-22 78.3 0.0 5.9e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EPE29239.1 - 5.3e-20 71.5 0.0 1.7e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 CPSase_L_D2 PF02786.17 EPE29242.1 - 3.6e-80 268.4 0.1 5.8e-80 267.7 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EPE29242.1 - 1.6e-68 230.4 0.0 3e-68 229.5 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EPE29242.1 - 2.5e-39 134.2 0.0 5e-39 133.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EPE29242.1 - 7.7e-32 109.6 0.0 2.2e-31 108.1 0.0 1.9 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EPE29242.1 - 7.5e-27 94.5 0.0 1.5e-26 93.6 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EPE29242.1 - 2.9e-18 65.4 6.0 5.7e-18 64.5 4.2 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EPE29242.1 - 1.2e-09 37.9 2.9 2.8e-06 27.1 0.2 3.1 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EPE29242.1 - 1.6e-09 37.6 0.0 3.2e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EPE29242.1 - 4.1e-07 29.7 0.0 9e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EPE29242.1 - 1.3e-05 24.9 0.0 3.3e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EPE29242.1 - 4.4e-05 23.6 0.0 9.9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EPE29242.1 - 0.00099 19.8 0.8 2.8 8.7 0.1 3.3 3 0 0 3 3 3 2 HlyD family secretion protein ATPgrasp_ST PF14397.6 EPE29242.1 - 0.0011 18.3 0.0 0.003 16.9 0.0 1.7 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 EPE29242.1 - 0.0081 15.8 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 EPE29242.1 - 0.0098 15.1 0.3 0.16 11.2 0.1 2.3 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_YheCD PF14398.6 EPE29242.1 - 0.026 13.8 0.0 0.64 9.2 0.0 2.3 1 1 0 2 2 2 0 YheC/D like ATP-grasp GARS_A PF01071.19 EPE29242.1 - 0.039 13.7 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2118 PF09891.9 EPE29242.1 - 0.064 13.2 0.1 0.17 11.8 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.6 EPE29242.1 - 0.11 12.4 2.0 0.57 10.2 1.5 2.1 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Clathrin PF00637.20 EPE29243.1 - 3.4e-209 685.1 33.2 2.4e-33 115.0 3.5 7.6 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EPE29243.1 - 2.5e-33 113.8 1.0 1.3e-32 111.5 0.1 2.8 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 EPE29243.1 - 1.7e-29 100.7 1.2 2.9e-06 27.3 0.0 6.6 6 0 0 6 6 6 6 Clathrin propeller repeat TPR_8 PF13181.6 EPE29243.1 - 0.00099 19.1 2.4 0.36 11.1 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Clathrin-link PF09268.10 EPE29243.1 - 0.0012 18.1 0.2 0.0033 16.8 0.2 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Vps39_1 PF10366.9 EPE29243.1 - 0.0041 17.4 5.7 5 7.5 0.0 6.0 5 1 1 6 6 6 1 Vacuolar sorting protein 39 domain 1 TPR_14 PF13428.6 EPE29243.1 - 0.0051 17.5 8.4 21 6.3 0.0 8.0 10 0 0 10 10 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 EPE29243.1 - 0.0065 16.4 5.5 16 5.8 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 EPE29243.1 - 0.021 14.6 1.6 6.7 6.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat 6PF2K PF01591.18 EPE29243.1 - 0.029 13.7 0.3 0.095 12.0 0.3 1.9 1 0 0 1 1 1 0 6-phosphofructo-2-kinase TPR_12 PF13424.6 EPE29243.1 - 0.059 13.7 0.2 34 4.8 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EPE29243.1 - 0.079 13.1 6.6 7.2 7.0 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1640 PF07798.11 EPE29244.1 - 3e-54 183.7 11.6 3.6e-54 183.4 11.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) XhlA PF10779.9 EPE29244.1 - 0.66 10.2 5.1 0.21 11.8 0.6 2.4 3 0 0 3 3 3 0 Haemolysin XhlA Peptidase_S46 PF10459.9 EPE29244.1 - 0.9 8.1 7.4 1.1 7.8 7.4 1.0 1 0 0 1 1 1 0 Peptidase S46 eIF2_C PF09173.11 EPE29245.1 - 2.1e-34 117.6 0.5 5.4e-34 116.3 0.5 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EPE29245.1 - 4.2e-23 81.9 0.4 3.2e-22 79.0 0.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EPE29245.1 - 1.7e-10 41.1 0.5 3.7e-10 40.0 0.5 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EPE29245.1 - 0.0037 17.3 0.0 0.0075 16.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPE29245.1 - 0.0053 16.7 0.2 0.062 13.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EPE29245.1 - 0.0071 16.4 0.1 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MFS_1 PF07690.16 EPE29247.1 - 1.3e-41 142.7 55.6 1.3e-41 142.7 55.6 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE29247.1 - 1.4e-07 30.3 29.9 1.9e-07 29.9 29.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CUE PF02845.16 EPE29248.1 - 7.5e-08 31.9 1.8 0.00029 20.5 0.1 2.5 2 0 0 2 2 2 2 CUE domain DMA PF03474.14 EPE29248.1 - 2e-06 27.3 0.2 0.049 13.2 0.0 2.6 2 0 0 2 2 2 2 DMRTA motif UBA PF00627.31 EPE29248.1 - 5.9e-06 26.1 4.7 0.00028 20.7 0.2 2.8 3 0 0 3 3 3 2 UBA/TS-N domain UBA_4 PF14555.6 EPE29248.1 - 0.1 12.4 2.2 2.5 8.0 0.1 2.4 2 0 0 2 2 2 0 UBA-like domain Pkinase PF00069.25 EPE29249.1 - 3.3e-69 233.2 0.0 5.4e-69 232.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE29249.1 - 3.8e-50 170.6 0.0 5.9e-50 170.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPE29249.1 - 0.00082 18.3 0.0 0.0016 17.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EPE29249.1 - 0.0078 15.6 0.0 0.28 10.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like DUF4061 PF13270.6 EPE29249.1 - 0.086 13.2 0.2 0.22 11.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) FXMRP1_C_core PF12235.8 EPE29249.1 - 0.094 13.4 1.8 0.23 12.1 1.8 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal SOG2 PF10428.9 EPE29249.1 - 9.8 5.2 25.7 31 3.6 25.7 1.6 1 1 0 1 1 1 0 RAM signalling pathway protein Thioredoxin_7 PF13899.6 EPE29250.1 - 5.2e-17 61.8 0.2 1.3e-16 60.5 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like UBA_4 PF14555.6 EPE29250.1 - 2.8e-11 43.1 0.0 1.1e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.20 EPE29250.1 - 0.00015 21.9 0.0 0.00027 21.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.15 EPE29250.1 - 0.012 15.6 0.1 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 EPE29250.1 - 0.016 15.7 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Ecm29 PF13001.7 EPE29251.1 - 3.1e-156 521.0 0.2 3.1e-156 521.0 0.2 2.8 4 0 0 4 4 4 1 Proteasome stabiliser IFRD PF05004.13 EPE29251.1 - 0.0012 18.1 3.0 0.0012 18.1 3.0 3.9 2 1 1 3 3 3 2 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 EPE29251.1 - 0.0066 16.9 13.6 65 4.2 0.1 8.9 9 1 1 10 10 10 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EPE29251.1 - 0.0083 16.7 1.4 0.33 11.6 0.1 3.7 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EPE29251.1 - 0.86 10.0 8.1 5 7.6 0.0 5.8 7 0 0 7 7 7 0 HEAT repeats HEAT PF02985.22 EPE29251.1 - 0.87 10.0 15.1 2.9 8.4 0.2 7.6 9 0 0 9 9 9 0 HEAT repeat PCI PF01399.27 EPE29252.1 - 6.6e-17 61.9 0.7 2.6e-16 60.0 0.7 2.1 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 EPE29252.1 - 2.1e-12 46.5 2.0 2.1e-12 46.5 2.0 2.3 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix DUF3781 PF12636.7 EPE29252.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) ADK PF00406.22 EPE29253.1 - 7.3e-48 162.5 0.1 9.4e-48 162.1 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EPE29253.1 - 5.3e-38 130.5 0.2 7.5e-38 130.0 0.2 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EPE29253.1 - 1.8e-07 31.7 0.0 2.6e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EPE29253.1 - 2.1e-05 24.7 0.0 0.00025 21.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 EPE29253.1 - 0.00016 21.4 0.7 0.034 13.8 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase EthD PF07110.11 EPE29254.1 - 1.2e-21 77.6 0.3 1.6e-21 77.2 0.3 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EPE29254.1 - 1.4e-07 32.0 0.1 2e-07 31.5 0.1 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase GSIII_N PF12437.8 EPE29254.1 - 0.18 11.4 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 Glutamine synthetase type III N terminal Acetyltransf_2 PF00797.17 EPE29255.1 - 8.2e-47 160.0 0.1 1e-46 159.7 0.1 1.1 1 0 0 1 1 1 1 N-acetyltransferase Peptidase_M20 PF01546.28 EPE29256.1 - 9.8e-29 100.5 0.0 1.4e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EPE29256.1 - 7.5e-07 29.0 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EPE29256.1 - 0.00084 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 FAD_binding_3 PF01494.19 EPE29258.1 - 7.5e-62 209.6 0.0 1.1e-61 209.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Amidohydro_1 PF01979.20 EPE29258.1 - 1.4e-22 80.5 0.0 2.6e-22 79.6 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPE29258.1 - 7.1e-11 42.2 0.0 1.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Phe_hydrox_dim PF07976.12 EPE29258.1 - 6.7e-06 26.2 0.0 5.1e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 EPE29258.1 - 8.1e-05 22.4 0.1 0.00053 19.7 0.0 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE29258.1 - 0.071 12.3 0.1 0.64 9.2 0.1 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiS PF02597.20 EPE29259.1 - 1.4e-09 38.5 0.0 1.8e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 ThiS family RNB PF00773.19 EPE29260.1 - 1.9e-48 165.5 0.0 3.9e-47 161.2 0.0 2.5 2 1 0 2 2 2 1 RNB domain S1 PF00575.23 EPE29260.1 - 0.13 12.6 0.1 0.31 11.4 0.1 1.6 1 0 0 1 1 1 0 S1 RNA binding domain CytochromB561_N PF09786.9 EPE29261.1 - 0.61 9.0 9.3 0.75 8.7 9.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Pkinase PF00069.25 EPE29262.1 - 1.4e-25 90.2 0.0 2.7e-24 86.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE29262.1 - 9.8e-07 28.3 0.1 0.0024 17.2 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase DUF2415 PF10313.9 EPE29263.1 - 0.083 12.8 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) DLH PF01738.18 EPE29266.1 - 6.4e-32 110.9 0.0 7.5e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family MOSC PF03473.17 EPE29267.1 - 7.1e-36 123.1 0.1 2.1e-35 121.6 0.0 1.8 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 EPE29267.1 - 2.7e-24 85.4 0.0 6.1e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 EPE29267.1 - 3.6e-21 75.5 0.0 6.9e-21 74.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Sod_Fe_C PF02777.18 EPE29268.1 - 2.7e-14 53.2 0.0 1.8e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EPE29268.1 - 0.076 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain SAM_2 PF07647.17 EPE29269.1 - 1.2e-09 38.2 0.0 2.2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EPE29269.1 - 2.2e-08 34.4 0.0 5.2e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 EPE29269.1 - 5e-07 30.2 0.0 2.4e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 PH domain SAM_3 PF18016.1 EPE29269.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Fungal_trans_2 PF11951.8 EPE29271.1 - 3.8e-87 292.6 0.1 4.7e-87 292.3 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE29271.1 - 1.8e-07 31.2 7.4 3.1e-07 30.4 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2235 PF09994.9 EPE29272.1 - 4.5e-75 252.7 0.0 6.4e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Palm_thioest PF02089.15 EPE29272.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase SHR3_chaperone PF08229.11 EPE29273.1 - 6.8e-82 273.0 0.0 7.9e-82 272.8 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF202 PF02656.15 EPE29273.1 - 0.14 12.7 3.3 5.7 7.5 2.6 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF5453 PF17534.2 EPE29273.1 - 0.48 10.4 6.2 0.39 10.6 4.2 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5453) Sugar_tr PF00083.24 EPE29274.1 - 7e-81 272.4 21.1 8.9e-81 272.0 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE29274.1 - 1.4e-21 76.8 26.9 1.4e-21 76.8 26.9 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1580 PF07618.11 EPE29275.1 - 0.08 12.6 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1580) HET PF06985.11 EPE29277.1 - 1.5e-16 61.1 0.0 3.8e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Yip1 PF04893.17 EPE29278.1 - 0.0065 16.2 0.6 0.0065 16.2 0.6 1.6 2 0 0 2 2 2 1 Yip1 domain Cu_bind_like PF02298.17 EPE29278.1 - 0.022 14.8 0.0 0.15 12.1 0.0 2.1 1 1 0 1 1 1 0 Plastocyanin-like domain Amnionless PF14828.6 EPE29278.1 - 0.16 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF202 PF02656.15 EPE29278.1 - 0.31 11.5 3.6 0.7 10.4 3.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) FmiP_Thoc5 PF09766.9 EPE29279.1 - 6e-32 111.3 9.6 7.9e-32 110.9 9.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 YfiO PF13525.6 EPE29279.1 - 0.0047 16.7 0.2 0.0067 16.2 0.2 1.3 1 0 0 1 1 1 1 Outer membrane lipoprotein Casc1_N PF15927.5 EPE29279.1 - 1.4 8.5 9.4 0.059 13.1 2.1 2.1 2 1 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus DUF4200 PF13863.6 EPE29279.1 - 1.7 9.1 9.7 0.66 10.4 0.9 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3958 PF13125.6 EPE29279.1 - 1.8 8.8 10.5 3.4 7.9 7.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) K-box PF01486.17 EPE29279.1 - 6 7.1 11.7 0.71 10.1 5.4 2.6 2 1 1 3 3 3 0 K-box region DUF3074 PF11274.8 EPE29280.1 - 4.6e-45 153.9 0.7 5.9e-45 153.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) DMRL_synthase PF00885.19 EPE29281.1 - 1e-54 184.2 0.0 1.3e-54 183.8 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Cation_efflux PF01545.21 EPE29283.1 - 3.5e-21 75.8 12.7 4.5e-21 75.5 12.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EPE29283.1 - 3.5e-06 27.1 0.1 6.7e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Rad60-SLD PF11976.8 EPE29284.1 - 2.7e-16 59.2 3.1 2.4e-15 56.1 0.6 3.0 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EPE29284.1 - 0.0034 17.1 0.2 0.23 11.3 0.1 2.7 2 1 0 2 2 2 1 Ubiquitin family TmoB PF06234.12 EPE29284.1 - 0.031 14.4 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) LSM PF01423.22 EPE29285.1 - 8.8e-22 76.6 0.2 1e-21 76.4 0.2 1.1 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 EPE29285.1 - 0.00013 22.0 0.3 0.00016 21.7 0.3 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 EPE29285.1 - 0.00014 21.9 0.2 0.00017 21.7 0.2 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 EPE29285.1 - 0.1 12.3 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Hfq protein Methyltransf_11 PF08241.12 EPE29286.1 - 3.4e-13 50.0 0.0 5.9e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE29286.1 - 1.9e-11 44.5 0.0 4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE29286.1 - 4.4e-06 27.4 0.0 7.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE29286.1 - 9.8e-05 21.8 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EPE29286.1 - 0.00013 21.9 0.1 0.00054 19.8 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE29286.1 - 0.00013 21.8 0.0 0.00036 20.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EPE29286.1 - 0.0008 19.6 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 EPE29286.1 - 0.026 14.4 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase PI3_PI4_kinase PF00454.27 EPE29287.1 - 1.1e-39 136.7 0.1 1e-36 127.1 0.1 3.0 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EPE29287.1 - 2e-26 92.6 0.1 5.9e-26 91.0 0.1 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Proteasome PF00227.26 EPE29288.1 - 2e-29 102.5 0.8 7.1e-29 100.6 0.8 1.9 1 1 0 1 1 1 1 Proteasome subunit EPSP_synthase PF00275.20 EPE29289.1 - 3.4e-130 434.5 0.0 5.3e-130 433.9 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EPE29289.1 - 2.6e-102 341.5 0.0 5.3e-102 340.5 0.0 1.5 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EPE29289.1 - 2.2e-58 198.2 0.0 3.8e-58 197.5 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EPE29289.1 - 1.7e-33 116.0 0.0 8.2e-32 110.5 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EPE29289.1 - 4.4e-24 84.6 0.0 1.1e-23 83.3 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 EPE29289.1 - 1.4e-07 31.5 0.0 3.8e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 EPE29289.1 - 3.7e-05 23.4 0.1 9.2e-05 22.1 0.1 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EPE29289.1 - 0.0002 21.4 0.0 0.0013 18.8 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EPE29289.1 - 0.018 15.3 0.0 0.21 11.8 0.0 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain bZIP_2 PF07716.15 EPE29290.1 - 0.012 15.6 8.0 0.012 15.6 8.0 1.8 2 0 0 2 2 2 0 Basic region leucine zipper Sporozoite_P67 PF05642.11 EPE29290.1 - 0.02 13.0 5.5 0.028 12.5 5.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AF-4 PF05110.13 EPE29290.1 - 0.21 9.6 17.3 0.23 9.5 17.3 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4551 PF15087.6 EPE29290.1 - 1.7 7.4 5.8 1.9 7.2 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC45 PF02724.14 EPE29290.1 - 1.8 6.8 11.5 2.5 6.3 11.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Secretin_N_2 PF07655.13 EPE29290.1 - 2 9.0 11.4 2 9.0 6.1 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Macoilin PF09726.9 EPE29290.1 - 2.4 6.6 7.5 2.6 6.5 7.5 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EPE29290.1 - 2.9 6.7 9.7 2.9 6.6 9.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain bZIP_1 PF00170.21 EPE29290.1 - 6.5 6.9 13.2 0.77 9.9 6.9 2.4 2 1 1 3 3 3 0 bZIP transcription factor GHMP_kinases_N PF00288.26 EPE29292.1 - 3e-17 62.6 0.0 6.4e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EPE29292.1 - 3.4e-11 43.4 0.1 7.9e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EPE29292.1 - 0.0018 17.8 0.0 0.0046 16.5 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.22 EPE29293.1 - 3.8e-38 128.1 11.6 4.9e-08 32.4 1.4 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PmoA PF14100.6 EPE29293.1 - 0.013 15.1 0.2 0.38 10.2 0.1 2.3 2 0 0 2 2 2 0 Methane oxygenase PmoA DUF4276 PF14103.6 EPE29293.1 - 0.36 11.0 2.9 0.18 12.0 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4276) SCP1201-deam PF14428.6 EPE29294.1 - 0.033 14.1 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 SCP1.201-like deaminase Spherulin4 PF12138.8 EPE29295.1 - 0.00022 21.0 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 Spherulation-specific family 4 Gram_pos_anchor PF00746.21 EPE29295.1 - 9.6 6.3 6.2 0.5 10.4 0.5 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Lipase_GDSL_2 PF13472.6 EPE29296.1 - 5.4e-10 39.9 1.1 9.1e-10 39.2 0.1 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Aspzincin_M35 PF14521.6 EPE29296.1 - 8.2e-09 36.2 2.9 2.5e-07 31.3 2.9 2.5 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Lipase_GDSL PF00657.22 EPE29296.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF4344 PF14247.6 EPE29296.1 - 0.12 12.1 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative metallopeptidase HSP70 PF00012.20 EPE29297.1 - 2.5e-98 329.8 0.1 1e-64 218.8 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein Styelin PF17562.2 EPE29297.1 - 0.11 12.9 0.1 0.26 11.7 0.1 1.6 1 0 0 1 1 1 0 Styelin Beta-lactamase PF00144.24 EPE29298.1 - 2.9e-31 108.9 0.0 6.5e-31 107.8 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 EPE29298.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 EPE29298.1 - 0.03 13.7 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase NAD_binding_10 PF13460.6 EPE29299.1 - 1.7e-13 50.9 0.1 2.6e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE29299.1 - 4.9e-07 29.5 0.2 7.3e-07 28.9 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPE29299.1 - 6.6e-06 25.9 0.9 8.8e-06 25.4 0.9 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EPE29299.1 - 0.00047 19.7 0.1 0.00064 19.2 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EPE29299.1 - 0.0084 15.3 0.4 0.013 14.7 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EPE29299.1 - 0.011 14.9 0.1 0.02 14.0 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 EPE29299.1 - 0.024 13.7 0.1 0.032 13.2 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Cytochrom_B561 PF03188.16 EPE29302.1 - 4.6e-19 68.9 4.2 7e-19 68.3 4.2 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Claudin_2 PF13903.6 EPE29302.1 - 0.016 15.0 2.6 1 9.0 0.0 2.8 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4079 PF13301.6 EPE29302.1 - 0.69 10.1 12.0 1.5 8.9 7.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF2231 PF09990.9 EPE29302.1 - 0.74 10.3 10.4 0.14 12.6 1.4 2.6 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) Allantoicase PF03561.15 EPE29303.1 - 2.4e-93 309.7 0.0 2e-46 157.5 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat DIL PF01843.19 EPE29304.1 - 8.4e-31 106.3 1.8 2e-30 105.1 1.8 1.7 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 EPE29304.1 - 1.8e-12 47.7 0.0 8.1e-12 45.6 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE29304.1 - 8.1e-09 35.6 0.0 2.1e-06 27.9 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPE29304.1 - 9.5e-09 35.6 0.0 0.0014 19.2 0.1 3.8 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EPE29304.1 - 5.9e-07 29.6 0.1 0.095 13.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EPE29304.1 - 3e-05 24.0 0.1 0.29 11.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat RabGAP-TBC PF00566.18 EPE29306.1 - 8.4e-37 126.9 0.0 1.2e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_M13_N PF05649.13 EPE29307.1 - 2e-96 324.0 0.1 2.5e-96 323.7 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EPE29307.1 - 1.3e-62 211.1 0.0 2.2e-62 210.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 PI3K_P85_iSH2 PF16454.5 EPE29307.1 - 0.21 11.2 0.0 0.69 9.5 0.0 1.9 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HATPase_c PF02518.26 EPE29308.1 - 5.3e-25 88.1 0.8 1.2e-24 87.0 0.8 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 EPE29308.1 - 5.7e-21 74.6 7.2 6e-12 45.7 2.6 4.1 4 0 0 4 4 4 3 PAS fold Response_reg PF00072.24 EPE29308.1 - 7e-21 74.5 0.0 1.9e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPE29308.1 - 1.3e-19 70.0 0.0 2.9e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 EPE29308.1 - 6.6e-10 39.0 0.0 5.8e-05 23.1 0.0 3.0 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 EPE29308.1 - 6.5e-09 36.0 0.4 7.2e-07 29.4 0.2 3.2 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 EPE29308.1 - 2e-08 34.4 0.0 0.089 13.0 0.0 3.7 4 0 0 4 4 4 2 PAS domain PAS_8 PF13188.7 EPE29308.1 - 0.0025 17.8 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 PAS domain PsbP PF01789.16 EPE29308.1 - 0.11 12.6 0.2 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 PsbP Ank_2 PF12796.7 EPE29309.1 - 3.7e-17 62.7 0.0 1.6e-05 25.4 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE29309.1 - 1.3e-12 47.9 0.4 0.0022 18.5 0.0 5.6 5 2 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE29309.1 - 1.4e-11 44.3 0.6 0.00072 19.8 0.0 5.9 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE29309.1 - 2e-09 36.9 1.0 0.0087 16.5 0.0 7.4 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.30 EPE29309.1 - 0.00028 21.2 0.1 2.4 8.7 0.0 5.3 5 1 0 5 5 5 1 Ankyrin repeat U3_snoRNA_assoc PF08297.11 EPE29310.1 - 0.037 14.7 10.3 0.077 13.7 10.3 1.5 1 0 0 1 1 1 0 U3 snoRNA associated OATP PF03137.20 EPE29310.1 - 0.039 12.2 0.2 0.056 11.7 0.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2254 PF10011.9 EPE29310.1 - 0.064 12.1 0.5 0.088 11.6 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF2052 PF09747.9 EPE29310.1 - 0.094 12.8 7.7 0.14 12.3 7.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.17 EPE29310.1 - 0.2 11.8 2.1 0.24 11.5 2.1 1.2 1 0 0 1 1 1 0 DDHD domain Vfa1 PF08432.10 EPE29310.1 - 0.21 11.9 14.1 0.37 11.1 14.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DAG_kinase_N PF14513.6 EPE29310.1 - 0.22 11.7 7.5 3.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus AP3D1 PF06375.11 EPE29310.1 - 0.39 11.0 13.6 0.67 10.2 13.6 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Peptidase_S49_N PF08496.10 EPE29310.1 - 0.41 10.7 10.4 0.15 12.1 7.6 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DASH_Spc19 PF08287.11 EPE29310.1 - 0.42 10.5 8.8 0.83 9.5 8.8 1.4 1 0 0 1 1 1 0 Spc19 FAM176 PF14851.6 EPE29310.1 - 0.58 9.8 4.1 0.9 9.2 4.1 1.3 1 0 0 1 1 1 0 FAM176 family DUF3807 PF12720.7 EPE29310.1 - 0.87 9.8 13.8 1.4 9.1 13.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) EIIBC-GUT_N PF03612.14 EPE29310.1 - 0.9 9.3 6.4 3.2 7.5 6.3 1.9 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus MMU163 PF17119.5 EPE29310.1 - 0.97 8.5 4.7 1.6 7.8 4.7 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Med19 PF10278.9 EPE29310.1 - 1.2 9.0 15.0 2.1 8.3 15.0 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 MAJIN PF15077.6 EPE29310.1 - 1.2 8.8 5.8 1.8 8.3 5.8 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein RPN2_C PF18004.1 EPE29310.1 - 1.5 8.7 15.4 2.9 7.8 15.4 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain V_ATPase_I PF01496.19 EPE29310.1 - 1.8 6.4 3.3 2.5 5.9 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 EPE29310.1 - 1.8 7.2 6.1 2.3 6.9 6.1 1.1 1 0 0 1 1 1 0 Presenilin Serinc PF03348.15 EPE29310.1 - 2 7.3 2.9 2.7 6.8 2.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Coilin_N PF15862.5 EPE29310.1 - 2.1 8.2 12.4 3.3 7.5 12.4 1.3 1 0 0 1 1 1 0 Coilin N-terminus NPR3 PF03666.13 EPE29310.1 - 7.1 5.3 8.3 9.1 4.9 8.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FUSC PF04632.12 EPE29311.1 - 1.2 7.5 6.5 2 6.9 6.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family NAD_binding_11 PF14833.6 EPE29312.1 - 9.9e-44 148.5 0.4 2.6e-25 89.0 0.0 2.4 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EPE29312.1 - 4.2e-34 118.0 0.0 9.1e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EPE29312.1 - 0.00055 20.5 0.0 0.0025 18.4 0.0 2.1 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EPE29312.1 - 0.0058 16.5 0.0 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EPE29312.1 - 0.016 14.9 0.1 0.038 13.6 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Arena_ncap_C PF17290.2 EPE29312.1 - 0.043 13.2 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain RasGEF PF00617.19 EPE29313.1 - 2.1e-44 151.8 0.2 3.2e-44 151.2 0.2 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EPE29313.1 - 6.6e-14 52.0 0.4 1.6e-13 50.8 0.4 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF615 PF04751.14 EPE29313.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Cir_N PF10197.9 EPE29315.1 - 4.7e-05 23.5 0.2 4.7e-05 23.5 0.2 4.5 4 1 1 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA PF00004.29 EPE29316.1 - 1.9e-55 186.9 0.0 1.7e-38 132.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 EPE29316.1 - 2.6e-10 39.9 0.8 2.3e-08 33.7 0.2 2.8 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 EPE29316.1 - 7.2e-10 39.3 0.1 0.00012 22.4 0.0 3.6 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 EPE29316.1 - 9.2e-10 39.2 0.1 0.00053 20.4 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 EPE29316.1 - 1.5e-09 37.5 0.1 0.00022 20.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_lid_3 PF17862.1 EPE29316.1 - 7.9e-09 35.2 0.1 1.8e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EPE29316.1 - 3.6e-08 33.3 0.1 0.003 17.3 0.0 3.1 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EPE29316.1 - 4.1e-08 33.3 0.2 0.003 17.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EPE29316.1 - 4.8e-08 33.3 0.0 4.7e-05 23.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EPE29316.1 - 7e-08 33.1 0.0 0.0092 16.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EPE29316.1 - 4.4e-07 30.2 0.0 0.018 15.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EPE29316.1 - 5.3e-07 29.2 0.1 0.0065 15.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EPE29316.1 - 6.4e-07 29.5 0.0 0.012 15.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EPE29316.1 - 2.5e-06 27.3 0.0 0.068 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EPE29316.1 - 4.1e-06 27.1 0.0 0.11 13.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 EPE29316.1 - 7e-06 25.7 0.2 0.023 14.2 0.0 2.7 3 0 0 3 3 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 EPE29316.1 - 2e-05 23.9 0.1 0.017 14.3 0.0 2.5 2 1 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.26 EPE29316.1 - 3.7e-05 23.5 0.0 0.3 10.8 0.0 2.9 3 0 0 3 3 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 EPE29316.1 - 4.5e-05 23.2 0.0 0.05 13.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.12 EPE29316.1 - 0.00012 22.0 0.5 0.12 12.2 0.0 3.4 4 0 0 4 4 3 1 NACHT domain AAA_17 PF13207.6 EPE29316.1 - 0.00013 22.4 0.1 0.043 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EPE29316.1 - 0.00018 21.8 0.0 0.36 11.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.27 EPE29316.1 - 0.0002 21.9 0.2 0.036 14.6 0.1 2.5 2 0 0 2 2 2 1 ABC transporter AAA_11 PF13086.6 EPE29316.1 - 0.00021 21.2 0.0 0.7 9.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EPE29316.1 - 0.00027 20.9 0.0 0.52 10.3 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EPE29316.1 - 0.00045 20.6 0.1 0.68 10.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 EPE29316.1 - 0.0005 19.5 0.8 0.042 13.2 0.1 2.6 2 1 0 2 2 2 1 KaiC AAA_30 PF13604.6 EPE29316.1 - 0.00091 19.0 0.0 0.86 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 EPE29316.1 - 0.0013 18.2 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 EPE29316.1 - 0.002 17.4 0.0 2.2 7.5 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 EPE29316.1 - 0.0027 16.9 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.15 EPE29316.1 - 0.0027 17.7 0.0 3.3 7.7 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 EPE29316.1 - 0.0029 17.5 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EPE29316.1 - 0.0037 16.9 1.2 3.2 7.3 0.0 3.3 2 2 1 3 3 3 1 AAA domain Zeta_toxin PF06414.12 EPE29316.1 - 0.0039 16.5 0.0 0.36 10.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin TniB PF05621.11 EPE29316.1 - 0.0043 16.5 0.1 5.8 6.3 0.0 3.2 3 1 1 4 4 3 0 Bacterial TniB protein KTI12 PF08433.10 EPE29316.1 - 0.0051 16.3 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 ATPase_2 PF01637.18 EPE29316.1 - 0.0054 16.7 0.7 42 3.9 0.0 3.8 2 2 1 4 4 4 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EPE29316.1 - 0.007 16.3 0.1 5.5 6.9 0.0 2.6 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 EPE29316.1 - 0.01 15.7 0.0 7.3 6.5 0.0 2.8 3 0 0 3 3 2 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 EPE29316.1 - 0.018 15.2 0.1 11 6.1 0.0 3.2 4 0 0 4 4 3 0 Sigma-54 interaction domain Hydin_ADK PF17213.3 EPE29316.1 - 0.03 14.6 0.1 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain SRP54 PF00448.22 EPE29316.1 - 0.03 13.9 0.0 3 7.4 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain CPT PF07931.12 EPE29316.1 - 0.076 12.9 0.1 0.87 9.4 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein IPT PF01745.16 EPE29316.1 - 0.089 12.2 0.0 0.87 8.9 0.0 2.1 2 0 0 2 2 2 0 Isopentenyl transferase Torsin PF06309.11 EPE29316.1 - 0.096 12.8 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Torsin Cytidylate_kin PF02224.18 EPE29316.1 - 0.1 12.3 0.0 6.8 6.4 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase ATP-synt_ab PF00006.25 EPE29316.1 - 0.1 12.2 0.1 8.4 6.0 0.0 2.9 2 2 1 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain CDC48_N PF02359.18 EPE29316.1 - 0.1 12.8 0.0 0.68 10.2 0.0 2.3 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain APS_kinase PF01583.20 EPE29316.1 - 0.15 12.0 0.0 20 5.1 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_29 PF13555.6 EPE29316.1 - 0.17 11.6 0.1 16 5.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 EPE29316.1 - 0.23 11.2 0.0 2.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SurE PF01975.17 EPE29317.1 - 5.7e-37 127.4 0.0 7.9e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Catalase_C PF18011.1 EPE29317.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain found in long catalases DUF3328 PF11807.8 EPE29319.1 - 1.9e-22 80.2 0.2 2.6e-22 79.7 0.2 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) TMEM174 PF15029.6 EPE29319.1 - 0.11 12.2 0.1 4.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 174 Dyp_perox PF04261.12 EPE29320.1 - 2.1e-07 30.3 0.0 1.5e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Dyp-type peroxidase family TFIID-18kDa PF02269.16 EPE29320.1 - 0.18 11.8 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit SHR-BD PF06650.12 EPE29321.1 - 8.6e-98 327.0 0.0 6.7e-96 320.8 0.0 3.1 3 1 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 EPE29321.1 - 1.5e-94 315.8 13.2 3.1e-94 314.8 0.4 5.0 6 0 0 6 6 6 2 Repeating coiled region of VPS13 VPS13 PF16908.5 EPE29321.1 - 1.1e-84 283.9 0.1 7.3e-83 278.0 0.0 3.4 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EPE29321.1 - 5e-75 251.2 5.8 2.8e-70 235.7 0.5 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EPE29321.1 - 4.4e-42 142.9 0.1 1.8e-41 140.9 0.1 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EPE29321.1 - 3e-08 33.9 0.1 1.3e-07 31.9 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain BLM10_mid PF16507.5 EPE29321.1 - 0.085 11.5 2.8 0.052 12.2 0.8 1.6 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, mid region DUF4736 PF15883.5 EPE29322.1 - 0.19 11.4 0.3 0.41 10.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) TFIID_20kDa PF03847.13 EPE29323.1 - 3.4e-19 69.1 0.0 4.7e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EPE29323.1 - 0.0038 17.5 0.0 0.0077 16.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EPE29323.1 - 0.031 14.3 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TFIID-18kDa PF02269.16 EPE29323.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit AhpC-TSA PF00578.21 EPE29324.1 - 8.8e-27 93.5 0.0 1.4e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EPE29324.1 - 3.5e-14 52.7 0.0 7.1e-14 51.8 0.0 1.4 1 1 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EPE29324.1 - 0.012 15.7 0.0 0.05 13.7 0.0 1.8 1 1 1 2 2 2 0 AhpC/TSA antioxidant enzyme CI-B14_5a PF07347.12 EPE29325.1 - 0.055 13.3 0.0 0.46 10.4 0.0 2.1 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) GTP_EFTU PF00009.27 EPE29326.1 - 1.3e-48 165.2 0.0 2.1e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EPE29326.1 - 8.6e-42 141.6 4.3 1.4e-41 140.9 4.3 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EPE29326.1 - 7.5e-20 70.8 0.0 1.5e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EPE29326.1 - 8e-06 26.2 0.0 1.7e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 EPE29326.1 - 9.6e-06 25.3 0.0 2.7e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 EPE29326.1 - 7.3e-05 22.8 0.0 0.00019 21.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EPE29326.1 - 0.003 17.0 0.0 0.0066 15.9 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.6 EPE29326.1 - 0.0044 17.1 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 EPE29326.1 - 0.028 14.2 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain MMR_HSR1_Xtn PF16897.5 EPE29326.1 - 0.065 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain HORMA PF02301.18 EPE29327.1 - 1.6e-31 109.6 0.0 1.8e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EPE29327.1 - 0.0011 19.0 0.4 0.0039 17.2 0.4 1.8 1 1 0 1 1 1 1 Autophagy-related protein 101 DUF2660 PF10859.8 EPE29327.1 - 0.0093 16.4 0.0 0.085 13.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2660) Arcadin_1 PF18653.1 EPE29327.1 - 0.016 15.3 0.4 1.4 9.0 0.1 2.2 1 1 1 2 2 2 0 Arcadin 1 Pex24p PF06398.11 EPE29328.1 - 2e-05 23.8 9.8 2e-05 23.8 9.8 1.6 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin PUMA PF15826.5 EPE29329.1 - 0.081 13.1 0.1 0.093 12.9 0.1 1.1 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis DUF883 PF05957.13 EPE29329.1 - 0.14 12.7 6.1 0.36 11.5 6.1 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EPE29329.1 - 9.9 6.8 13.5 1.7e+03 -0.4 13.5 2.4 1 1 0 1 1 1 0 YtxH-like protein His_Phos_1 PF00300.22 EPE29330.1 - 1.7e-10 40.9 0.1 1.5e-09 37.9 0.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1761 PF08570.10 EPE29331.1 - 7.2e-28 97.4 2.9 8.2e-28 97.2 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Acetyltransf_1 PF00583.25 EPE29332.1 - 3.7e-12 46.5 0.0 7.5e-12 45.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE29332.1 - 8e-08 32.3 0.1 1.1e-07 31.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE29332.1 - 9.3e-07 28.7 0.2 1.6e-06 28.0 0.2 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EPE29332.1 - 2.5e-05 24.6 0.0 5.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EPE29332.1 - 0.0092 15.5 0.3 0.014 14.9 0.1 1.4 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 EPE29332.1 - 0.01 15.9 0.1 0.019 15.0 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EPE29332.1 - 0.17 11.9 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase adh_short_C2 PF13561.6 EPE29333.1 - 1.1e-47 162.6 0.0 1.1e-42 146.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE29333.1 - 1.3e-47 161.8 0.0 1.5e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE29333.1 - 3.8e-16 59.5 0.0 5.1e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE29333.1 - 3.4e-05 23.4 0.0 0.00013 21.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EPE29333.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 EPE29333.1 - 0.21 10.9 0.0 2 7.7 0.0 2.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase tRNA-synt_1g PF09334.11 EPE29334.1 - 1.6e-149 498.0 0.0 3.2e-149 497.0 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EPE29334.1 - 1.1e-07 30.5 0.0 0.0036 15.6 0.0 3.2 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Yae1_N PF09811.9 EPE29335.1 - 7.8e-08 31.9 6.2 1.4e-07 31.1 6.2 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF1024 PF06260.12 EPE29335.1 - 0.002 18.4 0.1 0.0047 17.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1024) VPS28 PF03997.12 EPE29335.1 - 0.022 14.4 0.1 0.03 14.0 0.1 1.2 1 0 0 1 1 1 0 VPS28 protein DUF455 PF04305.14 EPE29335.1 - 0.063 12.8 0.0 0.082 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF455) Forkhead PF00250.18 EPE29336.1 - 2.3e-23 82.2 0.1 4.6e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EPE29336.1 - 5.5e-06 26.6 0.2 1.5e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 FHA domain FHA_2 PF17913.1 EPE29336.1 - 0.19 12.0 0.0 0.44 10.8 0.0 1.5 1 0 0 1 1 1 0 FHA domain BSP_II PF05432.11 EPE29336.1 - 7.7 6.1 23.3 0.021 14.5 11.1 2.6 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) STPPase_N PF16891.5 EPE29337.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Ten1 PF12658.7 EPE29338.1 - 6.3e-31 106.9 0.0 7.1e-31 106.7 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 EPE29338.1 - 8.2e-07 28.8 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.11 EPE29338.1 - 0.093 13.1 0.0 0.21 12.0 0.0 1.6 1 1 0 1 1 1 0 Replication factor A protein 3 Snf7 PF03357.21 EPE29339.1 - 1.4e-35 122.5 17.1 1.4e-35 122.5 17.1 2.0 2 0 0 2 2 2 1 Snf7 CCDC24 PF15669.5 EPE29339.1 - 0.00033 20.6 4.2 0.00075 19.4 4.2 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family DUF3138 PF11336.8 EPE29339.1 - 0.0057 15.3 3.7 0.009 14.7 3.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) DUF3854 PF12965.7 EPE29339.1 - 0.055 13.4 1.3 0.09 12.8 0.4 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3854) DUF948 PF06103.11 EPE29339.1 - 0.73 10.1 4.0 1.2 9.5 2.8 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Peptidase_C2 PF00648.21 EPE29341.1 - 1.9e-48 165.1 0.0 4.8e-47 160.4 0.0 2.3 1 1 0 1 1 1 1 Calpain family cysteine protease Arginase PF00491.21 EPE29342.1 - 2.2e-79 266.9 0.1 2.9e-79 266.5 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EPE29342.1 - 0.24 11.6 1.4 0.45 10.7 1.4 1.5 1 1 0 1 1 1 0 UPF0489 domain YchF-GTPase_C PF06071.13 EPE29345.1 - 5.1e-22 77.9 0.0 1.3e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EPE29345.1 - 3.3e-21 75.5 0.0 6.6e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPE29345.1 - 4.6e-08 32.7 0.0 9.2e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B GATA PF00320.27 EPE29348.1 - 3.6e-15 55.3 5.3 6e-15 54.6 5.3 1.4 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 EPE29348.1 - 0.39 11.0 1.6 0.89 9.9 1.6 1.6 1 0 0 1 1 1 0 zinc-ribbon GCS PF03074.16 EPE29349.1 - 1.1e-172 574.4 0.0 1.4e-172 574.2 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase SUR7 PF06687.12 EPE29351.1 - 2.5e-14 53.4 9.0 2.5e-14 53.4 9.0 1.6 1 1 1 2 2 2 1 SUR7/PalI family Trp_oprn_chp PF09534.10 EPE29351.1 - 0.0021 17.9 0.8 0.0034 17.2 0.2 1.6 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) L_HMGIC_fpl PF10242.9 EPE29351.1 - 0.14 12.4 10.6 0.033 14.4 1.8 2.6 1 1 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein COX4 PF02936.14 EPE29351.1 - 0.3 11.1 2.4 1.4 8.9 0.1 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase subunit IV Cadherin_C_2 PF16492.5 EPE29351.1 - 0.6 10.9 0.1 0.6 10.9 0.1 2.6 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 EPE29351.1 - 1.1 10.2 0.0 1.1 10.2 0.0 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain TRAM_LAG1_CLN8 PF03798.16 EPE29351.1 - 7.3 6.3 11.1 1.4 8.6 0.4 3.2 3 0 0 3 3 3 0 TLC domain zf-C2H2 PF00096.26 EPE29352.1 - 0.0017 18.7 16.0 0.15 12.6 0.7 4.4 3 1 0 3 3 3 3 Zinc finger, C2H2 type Raptor_N PF14538.6 EPE29352.1 - 0.0027 17.7 0.1 0.011 15.8 0.0 2.0 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain zf-C2H2_4 PF13894.6 EPE29352.1 - 0.0094 16.7 16.7 0.12 13.3 0.8 4.8 3 1 0 3 3 3 2 C2H2-type zinc finger Sina PF03145.16 EPE29352.1 - 0.058 13.3 2.5 0.16 11.9 2.5 1.7 1 0 0 1 1 1 0 Seven in absentia protein family zf-TRAF PF02176.18 EPE29352.1 - 0.094 13.4 0.7 0.33 11.7 0.7 2.0 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.8 EPE29352.1 - 0.28 11.5 2.2 14 6.1 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.25 EPE29353.1 - 3.1e-75 252.9 0.0 4.5e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE29353.1 - 8.7e-40 136.6 0.0 1.3e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EPE29353.1 - 5.1e-23 81.8 0.1 1.4e-10 41.6 0.0 3.1 3 0 0 3 3 3 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 EPE29353.1 - 6.8e-13 48.5 0.1 1.5e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EPE29353.1 - 5.9e-07 29.1 0.0 1.3e-06 28.0 0.0 1.5 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EPE29353.1 - 0.00044 19.9 0.3 0.00094 18.8 0.3 1.5 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EPE29353.1 - 0.00078 18.5 0.3 0.0021 17.1 0.3 1.8 1 1 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 EPE29353.1 - 0.0028 16.5 0.1 0.0056 15.6 0.1 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 EPE29353.1 - 0.05 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPE29353.1 - 0.095 12.6 0.2 0.48 10.3 0.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Gln-synt_C PF00120.24 EPE29355.1 - 3e-18 65.9 0.0 7.5e-13 48.2 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EPE29355.1 - 1.8e-13 50.0 0.0 3.7e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Transp_cyt_pur PF02133.15 EPE29356.1 - 2.8e-152 507.5 38.8 3.3e-152 507.3 38.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3772 PF12607.8 EPE29357.1 - 0.076 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) MFS_1 PF07690.16 EPE29358.1 - 3.1e-08 33.0 30.5 0.0049 15.8 0.0 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily GRP PF07172.11 EPE29358.1 - 3.9 8.2 18.4 15 6.3 18.4 2.1 1 0 0 1 1 1 0 Glycine rich protein family CN_hydrolase PF00795.22 EPE29359.1 - 1.4e-55 188.5 0.0 1.6e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Spermine_synth PF01564.17 EPE29360.1 - 3.1e-73 245.2 0.0 4.7e-73 244.6 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EPE29360.1 - 4.3e-25 87.4 0.2 7e-25 86.7 0.2 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EPE29360.1 - 0.00015 22.4 0.1 0.00038 21.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 EPE29360.1 - 0.0026 17.0 0.0 0.0042 16.3 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_12 PF08242.12 EPE29360.1 - 0.012 16.3 0.2 0.15 12.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.7 EPE29360.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 EPE29360.1 - 0.16 11.8 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase G-alpha PF00503.20 EPE29362.1 - 1.1e-108 363.6 0.5 1.3e-108 363.3 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EPE29362.1 - 6.1e-14 51.9 1.6 1.3e-09 37.7 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EPE29362.1 - 0.00014 21.3 0.4 0.045 13.1 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EPE29362.1 - 0.00021 21.5 0.5 0.36 11.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EPE29362.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 EPE29362.1 - 0.077 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PI_PP_C PF18365.1 EPE29362.1 - 0.082 12.9 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain zf-U1 PF06220.12 EPE29363.1 - 4.9e-16 58.2 2.1 7.1e-16 57.7 2.1 1.2 1 0 0 1 1 1 1 U1 zinc finger tRNA-synt_2b PF00587.25 EPE29364.1 - 1.1e-33 116.7 0.0 4e-32 111.6 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EPE29364.1 - 1.7e-09 37.7 0.1 3.7e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain EIIBC-GUT_C PF07663.11 EPE29364.1 - 0.2 11.8 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II C-terminus HLH PF00010.26 EPE29365.1 - 5.4e-09 35.9 0.1 1.3e-08 34.7 0.0 1.7 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain Maf PF02545.14 EPE29366.1 - 6.6e-49 166.0 0.0 8e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein ERG4_ERG24 PF01222.17 EPE29367.1 - 0.15 10.8 0.1 0.22 10.2 0.1 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family HVSL PF09749.9 EPE29368.1 - 6e-83 278.0 0.0 7e-83 277.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Pal1 PF08316.11 EPE29369.1 - 3.2e-10 40.9 0.3 2.4e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 Pal1 cell morphology protein DUF3419 PF11899.8 EPE29370.1 - 7.9e-162 538.8 0.0 1.2e-161 538.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 EPE29370.1 - 1.3e-11 44.6 0.0 1.2e-10 41.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE29370.1 - 2.7e-07 31.2 0.0 2e-06 28.4 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE29370.1 - 3.1e-05 24.7 0.0 0.00027 21.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE29370.1 - 3.6e-05 24.3 0.0 0.00036 21.1 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE29370.1 - 7.5e-05 22.6 0.0 0.00039 20.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE29370.1 - 0.00092 18.6 0.0 0.021 14.2 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EPE29370.1 - 0.0054 16.5 0.0 0.0097 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Noc2 PF03715.13 EPE29371.1 - 2.8e-128 427.4 1.3 3.6e-128 427.0 0.0 1.9 2 0 0 2 2 2 1 Noc2p family EST1_DNA_bind PF10373.9 EPE29371.1 - 0.048 13.1 3.8 0.64 9.4 0.1 2.5 2 1 0 2 2 2 0 Est1 DNA/RNA binding domain PseudoU_synth_2 PF00849.22 EPE29372.1 - 6.2e-29 101.1 0.0 1e-28 100.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ub-Mut7C PF14451.6 EPE29372.1 - 0.013 15.3 0.1 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin Auto_anti-p27 PF06677.12 EPE29372.1 - 0.022 14.9 0.2 0.055 13.6 0.2 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TGS PF02824.21 EPE29372.1 - 0.14 12.3 0.1 0.46 10.6 0.1 1.9 1 0 0 1 1 1 0 TGS domain S4 PF01479.25 EPE29372.1 - 0.26 11.0 1.0 0.56 10.0 1.0 1.5 1 0 0 1 1 1 0 S4 domain SNF2_N PF00176.23 EPE29373.1 - 3.5e-46 157.5 0.1 6e-46 156.8 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 EPE29373.1 - 7.1e-25 86.9 1.0 7.1e-25 86.9 1.0 2.1 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 EPE29373.1 - 8.9e-11 42.1 0.0 1.7e-09 38.0 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE29373.1 - 2.1e-07 31.1 0.0 7.4e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 EPE29373.1 - 0.034 13.0 0.5 2.1 7.2 0.0 2.6 3 0 0 3 3 3 0 P-loop containing NTP hydrolase pore-1 PTS_2-RNA PF01885.16 EPE29374.1 - 3.2e-32 112.0 0.0 4e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family MFS_1 PF07690.16 EPE29375.1 - 3.1e-24 85.5 32.4 2.1e-22 79.6 21.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE29375.1 - 6.4e-05 22.0 2.8 6.4e-05 22.0 2.8 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 EPE29375.1 - 2.6 6.3 10.8 2.1 6.6 1.2 2.7 2 1 1 3 3 3 0 Transmembrane secretion effector PAN_4 PF14295.6 EPE29376.1 - 0.046 13.6 2.1 0.2 11.6 0.4 2.6 2 0 0 2 2 2 0 PAN domain MatE PF01554.18 EPE29377.1 - 3.2e-58 196.0 21.5 1.4e-29 102.8 6.7 2.3 2 0 0 2 2 2 2 MatE E1-E2_ATPase PF00122.20 EPE29377.1 - 0.52 9.8 0.0 0.52 9.8 0.0 3.2 2 2 2 4 4 4 0 E1-E2 ATPase Epimerase PF01370.21 EPE29378.1 - 4.9e-10 39.3 0.0 8e-10 38.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPE29378.1 - 5.9e-05 22.7 0.0 0.00099 18.7 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EPE29378.1 - 0.0087 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EPE29378.1 - 0.01 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding adh_short PF00106.25 EPE29378.1 - 0.012 15.0 0.1 0.025 14.1 0.0 1.5 2 0 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 EPE29378.1 - 0.019 14.1 0.0 0.057 12.5 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.10 EPE29378.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF305 PF03713.13 EPE29379.1 - 0.21 11.7 0.1 0.31 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF305) PhyH PF05721.13 EPE29380.1 - 2.3e-55 188.1 0.0 2.8e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EPE29380.1 - 0.023 15.1 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase RRM_1 PF00076.22 EPE29381.1 - 1e-33 115.0 0.1 3.8e-16 58.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPE29381.1 - 3.5e-11 43.1 0.1 0.00039 20.5 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EPE29381.1 - 0.064 13.3 0.0 6.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EPE29381.1 - 0.07 13.2 2.5 1.5 8.9 0.0 2.8 3 0 0 3 3 3 0 RNA binding motif RabGAP-TBC PF00566.18 EPE29382.1 - 3e-50 170.8 0.0 4.8e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SHNi-TPR PF10516.9 EPE29383.1 - 8.4e-16 57.1 3.1 6.7e-15 54.3 0.4 2.8 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 EPE29383.1 - 5.4e-06 26.6 1.6 0.0016 18.7 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EPE29383.1 - 0.035 14.8 0.5 0.035 14.8 0.5 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EPE29383.1 - 0.044 13.9 6.1 0.21 11.8 1.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EPE29383.1 - 0.18 12.4 2.8 0.4 11.2 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 EPE29383.1 - 1.1 9.3 3.1 0.77 9.8 0.6 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPE29383.1 - 6.9 7.8 6.4 4.6 8.3 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DNA_pol_E_B PF04042.16 EPE29384.1 - 2.5e-58 196.9 0.1 5e-58 195.9 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B MFS_1 PF07690.16 EPE29386.1 - 2.5e-36 125.3 51.4 2.5e-36 125.3 51.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE29386.1 - 1e-11 44.4 13.7 1e-11 44.4 13.7 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter But2 PF09792.9 EPE29387.1 - 1.3e-42 145.6 1.1 1.3e-42 145.6 1.1 1.7 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain RrnaAD PF00398.20 EPE29388.1 - 7.1e-63 212.2 0.0 9.8e-63 211.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EPE29388.1 - 8e-08 32.9 0.0 1.7e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE29388.1 - 9.2e-06 26.2 0.0 2.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE29388.1 - 0.0002 21.2 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EPE29388.1 - 0.00022 20.6 0.0 0.00035 19.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EPE29388.1 - 0.00052 19.9 0.0 0.00091 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EPE29388.1 - 0.00085 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EPE29388.1 - 0.0012 18.4 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EPE29388.1 - 0.0013 19.4 0.0 0.0033 18.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EPE29388.1 - 0.0027 17.5 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein NodS PF05401.11 EPE29388.1 - 0.0049 16.5 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 EPE29388.1 - 0.051 13.0 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EPE29388.1 - 0.052 12.9 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRMT5 PF05185.16 EPE29388.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.7 EPE29388.1 - 0.17 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GCP_C_terminal PF04130.13 EPE29389.1 - 1.3e-99 333.6 0.1 1.9e-99 333.0 0.1 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EPE29389.1 - 1.5e-82 277.7 0.0 3.4e-82 276.5 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF3921 PF13060.6 EPE29389.1 - 0.023 14.7 0.1 0.064 13.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) SAGA-Tad1 PF12767.7 EPE29390.1 - 1.2e-62 211.8 0.0 1.5e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit WD40 PF00400.32 EPE29391.1 - 1.9e-25 88.6 30.6 0.00058 20.6 0.1 11.4 11 1 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE29391.1 - 6.5e-15 55.2 6.6 0.00012 22.4 0.4 6.7 4 3 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 EPE29391.1 - 0.017 14.4 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 0 CPSF A subunit region LigD_N PF13298.6 EPE29391.1 - 0.11 12.8 0.1 0.82 10.0 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase Ligase (LigD) TFIIIC_delta PF12657.7 EPE29391.1 - 0.11 12.4 0.4 0.6 10.0 0.4 2.2 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term FUSC_2 PF13515.6 EPE29392.1 - 7.6e-28 97.2 7.2 7.6e-28 97.2 7.2 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 EPE29392.1 - 5.7e-09 35.3 16.0 0.0095 14.8 0.9 4.7 5 0 0 5 5 5 3 Aluminium activated malate transporter ArAE_2_N PF10337.9 EPE29392.1 - 1e-05 24.8 0.6 1e-05 24.8 0.6 2.1 2 1 1 3 3 3 1 Putative ER transporter, 6TM, N-terminal FUSC PF04632.12 EPE29392.1 - 3.2e-05 22.7 13.2 0.015 13.9 0.0 3.2 3 0 0 3 3 3 3 Fusaric acid resistance protein family ArAE_2 PF10334.9 EPE29392.1 - 0.00022 21.1 0.1 0.001 19.0 0.0 2.0 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 DUF3792 PF12670.7 EPE29392.1 - 0.24 11.6 0.1 0.24 11.6 0.1 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF3792) Dynamin_N PF00350.23 EPE29393.1 - 7.5e-13 48.9 0.2 5.2e-12 46.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EPE29393.1 - 1.1e-05 25.5 0.0 0.00034 20.7 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPE29393.1 - 0.00015 21.7 0.0 0.00038 20.4 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EPE29393.1 - 0.00018 22.0 0.0 0.0015 19.0 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 EPE29393.1 - 0.0069 16.8 0.1 0.062 13.7 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain Gln_amidase PF15644.6 EPE29393.1 - 0.0073 17.3 0.1 0.17 12.9 0.0 2.6 2 0 0 2 2 2 1 Papain fold toxin 1, glutamine deamidase IIGP PF05049.13 EPE29393.1 - 0.048 12.7 0.0 0.092 11.8 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) SlyX PF04102.12 EPE29393.1 - 0.064 13.9 0.7 0.39 11.4 0.7 2.5 1 0 0 1 1 1 0 SlyX Tom5 PF10642.9 EPE29394.1 - 1.9e-21 75.8 0.1 2e-21 75.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase GDC-P PF02347.16 EPE29395.1 - 1.6e-180 600.5 0.0 1.1e-167 558.3 0.0 2.2 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 EPE29395.1 - 6.2e-06 25.7 0.0 1.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EPE29395.1 - 0.00013 21.0 0.0 0.00087 18.3 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EPE29395.1 - 0.02 14.2 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family CHCH PF06747.13 EPE29396.1 - 5.6e-09 35.9 13.8 1.5e-08 34.5 3.7 2.6 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 EPE29396.1 - 8e-05 22.6 5.8 0.0016 18.4 1.6 2.3 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EPE29396.1 - 0.024 14.6 9.5 0.77 9.8 0.8 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 EPE29396.1 - 0.098 13.0 7.1 3.7 7.9 0.9 2.8 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 DEAD PF00270.29 EPE29397.1 - 2.3e-38 131.7 0.0 4.7e-38 130.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE29397.1 - 3.2e-21 75.8 0.0 1e-20 74.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EPE29397.1 - 3.1e-20 72.2 0.0 5.8e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EPE29397.1 - 0.0019 18.2 0.1 0.027 14.5 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EPE29397.1 - 0.11 12.8 0.1 1.1 9.5 0.1 2.6 1 1 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.16 EPE29397.1 - 0.25 11.4 3.9 0.39 10.7 3.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UvrD-helicase PF00580.21 EPE29397.1 - 1.1 8.7 8.1 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain SNRNP27 PF08648.12 EPE29398.1 - 0.0068 16.5 0.1 0.014 15.4 0.1 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins MPLKIP PF15502.6 EPE29398.1 - 0.037 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein DUF3768 PF12599.8 EPE29398.1 - 0.071 13.1 0.0 9.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3768) RNA_pol_Rpb4 PF03874.16 EPE29400.1 - 3.2e-17 63.0 0.6 6.8e-17 61.9 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb4 Pribosyl_synth PF14572.6 EPE29401.1 - 1.8e-39 135.7 0.8 1.1e-33 116.8 0.1 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EPE29401.1 - 2.7e-30 104.7 0.0 7e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EPE29401.1 - 4.9e-13 48.9 0.3 9e-13 48.0 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EPE29401.1 - 0.067 12.6 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Sof1 PF04158.14 EPE29403.1 - 1.8e-30 105.1 20.2 3e-30 104.3 20.2 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EPE29403.1 - 1.7e-29 101.4 7.5 1.1e-05 26.0 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE29403.1 - 3.3e-10 40.1 0.8 0.2 11.9 0.0 4.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPE29403.1 - 0.00087 18.3 0.0 0.02 13.8 0.0 2.8 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 EPE29403.1 - 0.0023 17.9 0.3 9.6 6.3 0.0 4.3 3 2 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.16 EPE29403.1 - 0.014 14.0 0.2 0.97 7.9 0.1 2.8 1 1 2 3 3 3 0 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 EPE29403.1 - 0.14 11.0 0.5 4 6.3 0.0 2.6 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain RPN6_N PF18055.1 EPE29404.1 - 7.8e-47 158.4 0.7 3.2e-46 156.5 0.7 2.1 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EPE29404.1 - 1.4e-22 80.2 0.1 4.2e-22 78.6 0.1 1.8 1 0 0 1 1 1 1 PCI domain RPN6_C_helix PF18503.1 EPE29404.1 - 1.5e-10 40.6 0.5 4.7e-10 39.0 0.5 1.9 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_7 PF13176.6 EPE29404.1 - 3.1e-05 23.7 0.3 0.36 11.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EPE29404.1 - 0.0012 18.4 1.5 0.0012 18.4 1.5 2.3 1 1 1 2 2 2 1 MalT-like TPR region DDRGK PF09756.9 EPE29404.1 - 0.0031 17.2 1.6 0.0031 17.2 1.6 2.1 2 1 0 2 2 2 1 DDRGK domain TPR_12 PF13424.6 EPE29404.1 - 0.0093 16.2 13.8 11 6.4 1.0 5.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EPE29404.1 - 0.028 14.3 0.2 25 4.9 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF410 PF04190.13 EPE29404.1 - 0.032 14.0 1.0 0.17 11.7 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF410) DUF2153 PF09921.9 EPE29404.1 - 0.034 14.0 1.2 0.7 9.7 0.1 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2153) Med2 PF11214.8 EPE29404.1 - 0.043 14.0 0.1 0.19 11.9 0.1 2.1 1 0 0 1 1 1 0 Mediator complex subunit 2 HTH_Crp_2 PF13545.6 EPE29404.1 - 0.074 13.0 0.1 0.36 10.9 0.0 2.2 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DprA_WH PF17782.1 EPE29404.1 - 0.093 12.9 0.0 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 DprA winged helix domain TPR_1 PF00515.28 EPE29404.1 - 0.11 12.3 0.9 13 5.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2564 PF10819.8 EPE29404.1 - 0.33 11.3 2.5 0.62 10.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) Ras PF00071.22 EPE29406.1 - 4.8e-51 172.6 0.0 9.5e-51 171.6 0.0 1.5 1 0 0 1 1 1 1 Ras family Ank_2 PF12796.7 EPE29406.1 - 6.4e-36 122.8 0.1 1.2e-12 48.3 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE29406.1 - 1.5e-18 66.9 0.1 3.3e-06 27.5 0.0 4.3 3 2 2 5 5 4 4 Ankyrin repeats (many copies) Roc PF08477.13 EPE29406.1 - 2.3e-17 63.3 0.0 5e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ank_5 PF13857.6 EPE29406.1 - 1.4e-15 57.1 1.1 7.2e-05 23.0 0.1 5.5 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EPE29406.1 - 7.3e-15 54.7 10.0 0.0081 16.6 0.1 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 EPE29406.1 - 8.5e-13 47.2 2.7 0.35 11.6 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat DUF676 PF05057.14 EPE29406.1 - 0.00022 20.8 0.1 0.0063 16.0 0.1 2.3 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Arf PF00025.21 EPE29406.1 - 0.00029 20.4 0.0 0.00055 19.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Hydrolase_4 PF12146.8 EPE29406.1 - 0.00094 18.5 0.0 0.012 14.9 0.0 2.8 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPE29406.1 - 0.005 17.5 0.1 0.015 15.9 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family GTP_EFTU PF00009.27 EPE29406.1 - 0.0088 15.6 0.0 0.03 13.9 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EPE29406.1 - 0.029 14.5 0.0 0.07 13.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase PGAP1 PF07819.13 EPE29406.1 - 0.03 14.0 0.1 0.12 12.0 0.1 1.9 1 1 0 1 1 1 0 PGAP1-like protein FeoB_N PF02421.18 EPE29406.1 - 0.052 13.1 0.1 0.42 10.1 0.0 2.4 3 0 0 3 3 3 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EPE29406.1 - 0.11 12.4 0.0 10 6.0 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase p450 PF00067.22 EPE29407.1 - 3.4e-47 161.3 0.0 6.5e-47 160.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF871 PF05913.11 EPE29407.1 - 0.11 11.7 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) Ribosomal_L44 PF00935.19 EPE29409.1 - 2.4e-36 124.0 12.0 4.7e-36 123.1 12.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L44 RRM_1 PF00076.22 EPE29410.1 - 4.5e-15 55.2 0.0 9.1e-15 54.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPE29410.1 - 0.0084 15.7 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EPE29410.1 - 0.02 14.9 0.1 8 6.6 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF4646 PF15496.6 EPE29410.1 - 0.023 15.3 0.0 0.19 12.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) RRM_occluded PF16842.5 EPE29410.1 - 0.13 12.2 0.2 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif Abhydrolase_1 PF00561.20 EPE29411.1 - 6.9e-22 78.3 0.0 9.6e-21 74.6 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EPE29411.1 - 1.4e-14 54.1 0.0 2.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.7 EPE29411.1 - 0.011 16.3 0.0 0.024 15.2 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE29411.1 - 0.019 14.3 0.2 1.5 8.0 0.1 2.6 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Pro-kuma_activ PF09286.11 EPE29412.1 - 3e-44 150.8 0.0 5.6e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain WD40 PF00400.32 EPE29413.1 - 4.7e-18 65.2 5.9 0.0013 19.5 0.0 7.0 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE29413.1 - 2.9e-07 30.7 0.0 0.22 11.9 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPE29413.1 - 0.098 11.6 0.4 0.36 9.7 0.0 2.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DJ-1_PfpI PF01965.24 EPE29414.1 - 1.7e-13 50.7 0.0 2.8e-13 50.0 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EPE29414.1 - 2.7e-07 30.5 0.0 3.6e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like Amidase PF01425.21 EPE29415.1 - 9.2e-70 235.8 0.1 1.2e-69 235.5 0.1 1.0 1 0 0 1 1 1 1 Amidase EST1_DNA_bind PF10373.9 EPE29416.1 - 3.9e-13 49.5 0.0 7.1e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain zf-C2H2_3rep PF18868.1 EPE29416.1 - 0.058 14.1 0.4 0.2 12.3 0.4 1.9 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats HET PF06985.11 EPE29417.1 - 4.2e-25 88.8 1.3 4.2e-24 85.5 1.3 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cupin_2 PF07883.11 EPE29418.1 - 6.8e-05 22.5 0.1 8.5e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.7 EPE29418.1 - 0.01 15.8 0.1 0.022 14.6 0.1 1.5 1 1 0 1 1 1 0 ChrR Cupin-like domain PI-PLC-X PF00388.19 EPE29419.1 - 9.2e-57 190.7 0.3 1.7e-56 189.8 0.3 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EPE29419.1 - 1.2e-41 141.7 0.9 2.3e-41 140.7 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain Dysbindin PF04440.16 EPE29419.1 - 0.018 15.2 1.3 0.018 15.2 1.3 2.8 2 1 0 2 2 2 0 Dysbindin (Dystrobrevin binding protein 1) DAAD PF18752.1 EPE29419.1 - 0.048 13.5 1.9 0.13 12.1 1.9 1.7 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase Phosphodiest PF01663.22 EPE29421.1 - 7.3e-93 312.0 0.2 9.4e-93 311.6 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EPE29421.1 - 0.00021 20.8 0.1 0.023 14.1 0.0 2.2 1 1 1 2 2 2 2 Sulfatase DUF4083 PF13314.6 EPE29421.1 - 0.71 9.9 2.1 2.3 8.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) AA_permease_2 PF13520.6 EPE29422.1 - 6.8e-61 206.4 51.4 9.5e-61 205.9 51.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE29422.1 - 1.1e-13 50.6 42.7 1.7e-13 50.0 42.7 1.3 1 0 0 1 1 1 1 Amino acid permease HET PF06985.11 EPE29423.1 - 5e-33 114.5 1.7 2.3e-32 112.4 0.6 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) SNF2_N PF00176.23 EPE29424.1 - 1.6e-61 207.9 0.3 2.6e-61 207.3 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE29424.1 - 1.1e-17 64.3 0.0 2.8e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE29424.1 - 6.9e-10 39.2 0.2 2e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EPE29424.1 - 0.00035 20.4 0.0 0.0012 18.6 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 EPE29424.1 - 0.0023 16.9 0.1 0.0043 16.0 0.1 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 SlyX PF04102.12 EPE29424.1 - 0.0062 17.1 3.1 0.0062 17.1 3.1 3.1 4 0 0 4 4 4 1 SlyX ERCC3_RAD25_C PF16203.5 EPE29424.1 - 0.08 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF507 PF04368.13 EPE29424.1 - 1 9.2 3.9 0.36 10.8 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF507) APH PF01636.23 EPE29427.1 - 1.8e-09 37.9 0.0 1.8e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE29427.1 - 3.8e-08 33.2 0.0 4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase NFACT-C PF11923.8 EPE29430.1 - 1.8e-41 140.4 0.3 1.8e-41 140.4 0.3 3.2 3 0 0 3 3 3 1 NFACT protein C-terminal domain FbpA PF05833.11 EPE29430.1 - 2.5e-33 115.5 11.4 2.5e-33 115.5 11.4 1.9 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 EPE29430.1 - 3e-29 101.8 0.0 6.8e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain Cas_TM1802 PF09484.10 EPE29430.1 - 0.064 12.0 2.8 0.13 11.0 2.8 1.4 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) Metallophos PF00149.28 EPE29433.1 - 2e-13 51.3 0.1 2.7e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Tannase PF07519.11 EPE29434.1 - 2.6e-100 336.5 0.0 3.2e-100 336.3 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 EPE29434.1 - 0.003 16.9 0.0 0.0069 15.7 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE29434.1 - 0.045 13.4 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPE29434.1 - 0.065 12.7 0.6 6.6 6.1 0.1 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Isy1 PF06246.12 EPE29436.1 - 1.3e-83 280.5 0.1 1.4e-83 280.4 0.1 1.0 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 EPE29436.1 - 0.0046 17.0 0.0 0.0094 16.0 0.0 1.5 1 0 0 1 1 1 1 YolD-like protein MMR_HSR1 PF01926.23 EPE29437.1 - 1.1e-14 54.5 0.0 2.2e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPE29437.1 - 3.1e-05 23.9 0.2 8.2e-05 22.6 0.2 1.7 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EPE29437.1 - 3.3e-05 23.4 0.0 5.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EPE29437.1 - 0.00011 22.3 1.0 0.22 11.6 0.1 3.1 2 1 1 3 3 3 2 Dynamin family IIGP PF05049.13 EPE29437.1 - 0.0014 17.7 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Roc PF08477.13 EPE29437.1 - 0.0058 16.9 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EPE29437.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 AIG1 family AAA_18 PF13238.6 EPE29437.1 - 0.033 14.7 0.3 0.13 12.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EPE29437.1 - 0.039 13.2 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 EPE29437.1 - 0.12 11.8 0.9 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit HCO3_cotransp PF00955.21 EPE29438.1 - 2.2e-70 237.9 12.5 2.2e-39 135.7 0.1 2.1 1 1 1 2 2 2 2 HCO3- transporter family TAL_FSA PF00923.19 EPE29439.1 - 2.7e-91 305.9 0.2 3.1e-91 305.7 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase CNH PF00780.22 EPE29440.1 - 4.2e-77 259.5 0.0 6.5e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EPE29440.1 - 5.1e-28 98.5 0.1 1e-27 97.6 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 EPE29440.1 - 5.2e-14 52.5 0.1 4e-13 49.6 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EPE29440.1 - 2.2e-05 24.9 1.0 0.00066 20.1 0.0 2.8 3 0 0 3 3 3 1 PH domain PH_16 PF17838.1 EPE29440.1 - 0.0019 18.1 0.5 0.46 10.3 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_13 PF16652.5 EPE29440.1 - 0.0073 16.1 1.5 0.3 10.9 0.0 3.1 2 1 1 3 3 3 1 Pleckstrin homology domain Fungal_trans PF04082.18 EPE29441.1 - 1.3e-24 86.7 0.4 2e-24 86.1 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE29441.1 - 3.1e-05 24.0 2.3 5.5e-05 23.2 2.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_4 PF12799.7 EPE29442.1 - 5.9e-07 29.7 5.0 3.3 8.3 0.0 6.3 4 2 4 8 8 7 1 Leucine Rich repeats (2 copies) TPR_1 PF00515.28 EPE29442.1 - 6.3e-06 25.8 4.8 0.066 13.1 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat F-box-like PF12937.7 EPE29442.1 - 9.9e-06 25.4 0.9 2.1e-05 24.3 0.9 1.6 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.17 EPE29442.1 - 0.00031 20.6 2.8 0.65 10.2 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat LRR_8 PF13855.6 EPE29442.1 - 0.0034 17.1 4.1 2.6 7.9 0.0 4.5 3 2 1 4 4 4 1 Leucine rich repeat TPR_12 PF13424.6 EPE29442.1 - 0.0079 16.5 2.9 0.37 11.1 1.1 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EPE29442.1 - 0.0093 16.1 0.1 4 7.6 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EPE29442.1 - 0.011 15.5 4.4 1.8 8.5 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat F-box PF00646.33 EPE29442.1 - 0.013 15.4 0.2 0.031 14.2 0.2 1.6 1 0 0 1 1 1 0 F-box domain LRR_6 PF13516.6 EPE29442.1 - 0.017 15.1 0.8 2.8 8.2 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat TPR_14 PF13428.6 EPE29442.1 - 0.021 15.6 1.1 0.34 11.9 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat COPI_C PF06957.11 EPE29442.1 - 0.049 12.4 0.1 0.075 11.8 0.1 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus TPR_16 PF13432.6 EPE29442.1 - 0.077 13.7 0.9 0.21 12.3 0.9 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat IDO PF01231.18 EPE29443.1 - 1.3e-170 567.9 0.0 1.5e-170 567.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.13 EPE29444.1 - 9.8e-33 112.6 0.1 4.8e-30 103.9 0.1 2.4 1 1 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EPE29444.1 - 1.7e-20 72.7 0.2 4.5e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.26 EPE29444.1 - 0.037 13.7 0.1 0.072 12.7 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme STE2 PF02116.15 EPE29446.1 - 1.5e-70 237.7 24.7 1.8e-70 237.5 24.7 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Abhydrolase_3 PF07859.13 EPE29447.1 - 2.3e-11 44.0 0.2 2.3e-05 24.4 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EPE29447.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Aminotran_5 PF00266.19 EPE29448.1 - 1.1e-25 90.5 0.0 1.4e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V CRM1_C PF08767.11 EPE29450.1 - 3.2e-135 450.4 1.0 3.2e-135 450.4 1.0 3.1 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EPE29450.1 - 2.3e-41 141.3 10.6 1.4e-40 138.8 6.6 3.9 2 1 1 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EPE29450.1 - 6.7e-34 115.3 4.0 2e-33 113.8 4.0 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EPE29450.1 - 7.4e-29 99.6 2.5 2.8e-28 97.8 1.2 2.8 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EPE29450.1 - 3.1e-20 71.4 1.3 7.9e-20 70.1 1.3 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EPE29450.1 - 2e-12 46.8 0.2 7.5e-12 45.0 0.2 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Sec7_N PF12783.7 EPE29450.1 - 0.0023 17.8 11.9 0.26 11.2 0.2 3.9 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Vac14_Fab1_bd PF12755.7 EPE29450.1 - 0.051 14.2 0.9 3.2 8.4 0.0 4.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EPE29450.1 - 0.28 11.1 8.4 0.35 10.8 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF3385) Ecl1 PF12855.7 EPE29451.1 - 1.4e-14 55.7 26.0 1.7e-14 55.4 26.0 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins DNA_processg_A PF02481.15 EPE29452.1 - 0.027 13.7 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 DNA recombination-mediator protein A Curlin_rpt PF07012.12 EPE29454.1 - 0.068 13.2 0.1 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 Curlin associated repeat SAP130_C PF16014.5 EPE29454.1 - 0.33 10.0 14.1 0.39 9.8 14.1 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus YabA PF06156.13 EPE29455.1 - 0.0012 19.5 12.4 0.14 12.8 4.0 3.2 1 1 3 4 4 4 2 Initiation control protein YabA Spc7 PF08317.11 EPE29455.1 - 0.02 13.8 20.0 0.077 11.9 19.9 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4709 PF15821.5 EPE29455.1 - 0.095 13.0 3.7 0.11 12.7 2.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4709) TSC22 PF01166.18 EPE29455.1 - 0.12 12.7 7.8 4.1 7.8 1.0 3.6 2 1 1 3 3 3 0 TSC-22/dip/bun family FtsQ PF03799.15 EPE29455.1 - 0.13 13.1 2.2 0.24 12.2 1.1 2.0 1 1 2 3 3 3 0 Cell division protein FtsQ DUF1664 PF07889.12 EPE29455.1 - 0.9 9.6 6.4 1.4 9.0 0.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PCRF PF03462.18 EPE29455.1 - 1.7 8.4 11.1 0.2 11.5 0.6 2.2 2 0 0 2 2 2 0 PCRF domain DUF87 PF01935.17 EPE29455.1 - 2.9 7.9 8.4 0.16 12.0 1.0 2.1 1 1 1 2 2 2 0 Helicase HerA, central domain Peptidase_M20 PF01546.28 EPE29457.1 - 7.7e-05 22.5 0.1 0.00011 22.0 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EPE29457.1 - 0.055 13.4 0.2 0.19 11.7 0.2 2.0 2 1 0 2 2 2 0 Peptidase dimerisation domain MFS_1 PF07690.16 EPE29458.1 - 8.2e-29 100.6 36.5 1.1e-28 100.2 36.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_18 PF00704.28 EPE29459.1 - 2.6e-19 70.1 0.2 9.4e-19 68.3 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 SKG6 PF08693.10 EPE29460.1 - 1.2e-09 37.4 4.8 3.7e-09 35.8 4.8 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CcmD PF04995.14 EPE29460.1 - 0.0037 17.3 0.8 0.0066 16.5 0.8 1.4 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) Rax2 PF12768.7 EPE29460.1 - 0.0039 16.7 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TMEM154 PF15102.6 EPE29460.1 - 0.0043 16.9 0.0 0.0043 16.9 0.0 3.6 1 1 1 2 2 2 1 TMEM154 protein family Shugoshin_N PF07558.11 EPE29461.1 - 1.9e-17 62.9 5.3 1.9e-17 62.9 5.3 2.3 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 EPE29461.1 - 6.8e-11 41.8 5.1 6.8e-11 41.8 5.1 3.3 3 0 0 3 3 3 1 Shugoshin C terminus KASH_CCD PF14662.6 EPE29461.1 - 0.084 12.7 2.1 1 9.2 0.6 2.5 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DASH_Dad2 PF08654.10 EPE29462.1 - 1.6e-34 118.2 0.4 2.1e-34 117.9 0.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 EPE29462.1 - 0.046 13.5 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF5407 PF17401.2 EPE29462.1 - 0.13 12.5 0.1 0.23 11.7 0.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5407) COesterase PF00135.28 EPE29464.1 - 9.7e-90 301.9 0.0 1.2e-89 301.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE29464.1 - 0.00077 19.4 1.0 0.057 13.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold TMEM154 PF15102.6 EPE29465.1 - 0.021 14.7 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.10 EPE29465.1 - 0.61 9.5 3.5 1 8.8 3.5 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HA2 PF04408.23 EPE29466.1 - 5e-18 65.4 0.1 1.1e-17 64.3 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EPE29466.1 - 2.2e-13 50.4 0.0 4.7e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EPE29466.1 - 2.6e-12 47.1 0.0 6.2e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EPE29466.1 - 5.2e-06 26.8 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EPE29466.1 - 0.00014 21.7 0.1 0.00029 20.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EPE29466.1 - 0.00055 19.7 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPE29466.1 - 0.0022 18.3 0.0 0.0074 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 EPE29466.1 - 0.015 14.9 0.1 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EPE29466.1 - 0.021 15.0 0.1 0.07 13.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EPE29466.1 - 0.034 13.2 0.0 0.075 12.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 EPE29466.1 - 0.16 11.2 0.4 0.69 9.2 0.1 2.1 1 1 1 2 2 2 0 Zeta toxin AAA_23 PF13476.6 EPE29466.1 - 0.43 11.1 1.3 1 9.9 1.2 1.7 1 1 0 1 1 1 0 AAA domain AT_hook PF02178.19 EPE29467.1 - 0.21 11.6 7.1 0.91 9.6 7.1 2.2 1 0 0 1 1 1 0 AT hook motif Glyco_hydro_76 PF03663.14 EPE29468.1 - 1e-151 505.7 13.3 1.2e-151 505.4 13.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EPE29468.1 - 0.0073 15.4 6.4 0.29 10.2 0.5 2.7 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 MLTD_N PF06474.12 EPE29468.1 - 0.023 14.8 0.0 0.075 13.2 0.0 1.8 1 0 0 1 1 1 0 MltD lipid attachment motif Sdh5 PF03937.16 EPE29470.1 - 4.1e-23 81.1 0.3 1.2e-22 79.6 0.4 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Nebulin PF00880.18 EPE29471.1 - 0.0015 18.4 0.4 0.3 11.0 0.2 2.6 2 0 0 2 2 2 2 Nebulin repeat TFIIA PF03153.13 EPE29471.1 - 0.0053 16.8 1.0 0.0053 16.8 1.0 1.8 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF3433 PF11915.8 EPE29472.1 - 2.6e-38 130.4 8.1 2.3e-21 76.0 0.9 4.1 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Orai-1 PF07856.12 EPE29472.1 - 3.7 7.2 8.9 2.6 7.7 0.0 2.9 3 0 0 3 3 3 0 Mediator of CRAC channel activity VirB3 PF05101.13 EPE29472.1 - 7.7 6.8 10.0 0.43 10.8 2.2 2.8 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein PIG-F PF06699.11 EPE29473.1 - 7.2e-65 218.5 4.9 8.5e-65 218.3 4.9 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_OmpA PF13436.6 EPE29473.1 - 2.9 7.8 7.7 10 6.0 0.7 2.2 2 0 0 2 2 2 0 Glycine-zipper domain Gly-zipper_YMGG PF13441.6 EPE29473.1 - 4.3 7.1 5.4 25 4.7 5.4 2.0 1 1 0 1 1 1 0 YMGG-like Gly-zipper Ank_2 PF12796.7 EPE29474.1 - 3.6e-28 98.0 0.7 2e-10 41.1 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE29474.1 - 4.8e-23 81.2 3.2 2.5e-06 27.9 0.0 6.1 5 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE29474.1 - 8.8e-16 56.4 6.0 0.01 16.3 0.1 6.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EPE29474.1 - 2.8e-14 53.0 3.5 0.0055 17.0 0.0 5.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) CUE PF02845.16 EPE29474.1 - 7.2e-13 48.0 0.0 2.3e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 CUE domain SPX PF03105.19 EPE29474.1 - 2.8e-12 47.3 33.8 2.6e-09 37.5 2.1 4.6 2 2 1 4 4 4 3 SPX domain Ank PF00023.30 EPE29474.1 - 1.5e-08 34.7 12.1 0.58 10.7 0.1 6.7 7 0 0 7 7 7 3 Ankyrin repeat GDPD PF03009.17 EPE29474.1 - 2.1e-07 31.0 0.0 1.1e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Rsa3 PF14615.6 EPE29474.1 - 0.21 11.2 1.3 2.3 7.8 0.1 3.0 3 0 0 3 3 3 0 Ribosome-assembly protein 3 Enkurin PF13864.6 EPE29475.1 - 0.0074 16.7 0.2 0.013 15.9 0.2 1.4 1 0 0 1 1 1 1 Calmodulin-binding DUF2207 PF09972.9 EPE29475.1 - 0.16 10.7 0.1 0.65 8.7 0.0 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Coa1 PF08695.10 EPE29476.1 - 3.6e-39 133.1 0.0 4.6e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Mtc PF03820.17 EPE29476.1 - 0.087 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Tricarboxylate carrier Ribosomal_L3 PF00297.22 EPE29477.1 - 3.6e-13 49.2 3.0 2.4e-10 39.9 1.2 2.4 2 1 1 3 3 3 2 Ribosomal protein L3 NFACT-R_1 PF05670.13 EPE29478.1 - 2.8e-38 130.9 0.3 1e-37 129.1 0.3 1.9 1 1 0 1 1 1 1 NFACT protein RNA binding domain ATP-synt_E PF05680.12 EPE29478.1 - 3.1 8.2 8.0 5.8 7.3 8.0 1.4 1 0 0 1 1 1 0 ATP synthase E chain PITH PF06201.13 EPE29479.1 - 1.3e-45 155.4 0.1 1.5e-45 155.1 0.1 1.1 1 0 0 1 1 1 1 PITH domain AA_permease PF00324.21 EPE29481.1 - 5.1e-129 431.0 37.4 6.3e-129 430.7 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE29481.1 - 1.8e-32 112.7 40.2 2.6e-32 112.2 40.2 1.2 1 0 0 1 1 1 1 Amino acid permease HhH-GPD PF00730.25 EPE29482.1 - 2.9e-18 66.3 0.0 7.4e-18 65.0 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EPE29482.1 - 3e-07 30.0 0.0 8.4e-07 28.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Amino_oxidase PF01593.24 EPE29483.1 - 1.3e-43 149.9 0.0 5.7e-42 144.6 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPE29483.1 - 7e-16 58.2 0.0 1.6e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE29483.1 - 1.4e-05 24.5 0.1 9.2e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE29483.1 - 2.4e-05 23.2 0.2 0.0074 15.0 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 EPE29483.1 - 3.5e-05 23.5 1.5 0.0001 22.0 0.9 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EPE29483.1 - 0.00024 21.6 0.5 0.0011 19.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EPE29483.1 - 0.00059 19.2 0.3 0.00087 18.6 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EPE29483.1 - 0.0014 18.0 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EPE29483.1 - 0.0014 18.6 0.5 0.74 9.8 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EPE29483.1 - 0.0023 17.1 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EPE29483.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EPE29483.1 - 0.03 14.2 0.2 0.067 13.1 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EPE29483.1 - 0.044 13.1 0.1 0.071 12.5 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPE29483.1 - 0.07 12.4 1.0 0.3 10.3 0.4 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EPE29483.1 - 0.1 11.6 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EPE29483.1 - 0.18 10.8 0.3 0.32 10.0 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GDPD PF03009.17 EPE29484.1 - 1.5e-32 113.3 0.0 2.4e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EPE29484.1 - 0.0017 18.8 0.1 0.0053 17.2 0.1 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family V_ATPase_I PF01496.19 EPE29485.1 - 0.78 7.6 4.0 0.93 7.3 4.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SET PF00856.28 EPE29487.1 - 0.00026 21.4 0.0 0.00067 20.1 0.0 1.8 2 0 0 2 2 2 1 SET domain Desmo_N PF06771.11 EPE29487.1 - 0.023 15.0 0.1 0.066 13.6 0.1 1.8 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus Fungal_trans PF04082.18 EPE29488.1 - 8.6e-34 116.8 0.7 1.6e-33 115.9 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MMR_HSR1_C PF08438.10 EPE29490.1 - 6.6e-37 126.5 0.0 1.2e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EPE29490.1 - 9.6e-21 74.0 0.0 2.8e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPE29490.1 - 9e-10 38.3 0.1 1.7e-07 30.9 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EPE29490.1 - 0.001 18.7 0.0 0.22 11.1 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EPE29490.1 - 0.0088 15.8 0.1 1.9 8.2 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EPE29490.1 - 0.01 15.8 1.2 0.25 11.2 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 EPE29490.1 - 0.018 15.6 0.1 0.67 10.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 EPE29490.1 - 0.025 14.7 1.6 0.14 12.2 0.2 2.4 3 0 0 3 3 3 0 Dynamin family MMR_HSR1_Xtn PF16897.5 EPE29490.1 - 0.058 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Ploopntkinase3 PF18751.1 EPE29490.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 KTI12 PF08433.10 EPE29490.1 - 0.087 12.3 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 EPE29490.1 - 0.16 12.4 0.3 1.1 9.6 0.3 2.3 1 1 0 1 1 1 0 AAA ATPase domain Pmp3 PF01679.17 EPE29491.1 - 5.5e-25 87.3 8.3 6.1e-25 87.2 8.3 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Ribosomal_L22e PF01776.17 EPE29492.1 - 2e-46 156.9 1.0 2.5e-46 156.5 1.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Glyco_transf_8 PF01501.20 EPE29493.1 - 1.7e-07 31.1 0.1 2.2e-06 27.4 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.27 EPE29494.1 - 6.3e-52 173.5 1.4 1.2e-16 60.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4677 PF15726.5 EPE29494.1 - 0.016 15.4 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) Nucleopor_Nup85 PF07575.13 EPE29495.1 - 4.5e-15 55.2 0.0 3.7e-05 22.5 0.0 4.2 3 1 0 3 3 3 3 Nup85 Nucleoporin Tubulin PF00091.25 EPE29496.1 - 5.5e-68 229.1 0.0 8.3e-68 228.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EPE29496.1 - 2.6e-46 156.9 0.6 5e-46 156.0 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EPE29496.1 - 4.7e-07 30.1 0.0 9.8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EPE29496.1 - 0.096 12.4 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Tubulin domain PLAT PF01477.23 EPE29497.1 - 0.14 12.7 0.2 0.23 12.0 0.2 1.3 1 0 0 1 1 1 0 PLAT/LH2 domain MgsA_C PF12002.8 EPE29499.1 - 1.7e-60 203.8 0.0 2.7e-60 203.1 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EPE29499.1 - 6.9e-23 80.8 0.2 1.6e-22 79.6 0.2 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EPE29499.1 - 2.4e-12 47.4 0.0 6.9e-12 45.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EPE29499.1 - 9e-08 32.0 0.0 2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EPE29499.1 - 4.3e-06 26.3 0.1 0.022 14.2 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EPE29499.1 - 0.00012 21.8 0.1 0.012 15.3 0.1 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EPE29499.1 - 0.0003 21.2 0.2 0.05 14.0 0.1 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EPE29499.1 - 0.00043 20.3 0.0 0.013 15.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EPE29499.1 - 0.00053 19.8 0.0 0.0018 18.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPE29499.1 - 0.00074 19.8 0.0 0.0022 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 EPE29499.1 - 0.0065 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF815 PF05673.13 EPE29499.1 - 0.011 14.9 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 EPE29499.1 - 0.041 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 EPE29499.1 - 0.052 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_28 PF13521.6 EPE29499.1 - 0.066 13.5 0.2 0.24 11.6 0.2 1.9 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 EPE29499.1 - 0.07 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EPE29499.1 - 0.1 12.3 0.4 0.34 10.6 0.4 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EPE29499.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CPT PF07931.12 EPE29499.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TIP49 PF06068.13 EPE29499.1 - 0.26 10.4 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain TRI5 PF06330.11 EPE29500.1 - 0.076 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) Lipase_3 PF01764.25 EPE29501.1 - 1.3e-28 99.6 0.0 1.9e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 EPE29501.1 - 0.00019 21.2 0.0 0.00031 20.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EPE29501.1 - 0.00026 21.6 2.4 0.00059 20.5 2.6 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE29501.1 - 0.0041 16.4 0.0 0.0064 15.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EPE29501.1 - 0.009 16.1 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 EPE29501.1 - 0.041 13.7 0.2 0.059 13.2 0.2 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 EPE29501.1 - 0.064 12.9 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase AXE1 PF05448.12 EPE29501.1 - 0.075 11.7 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.7 EPE29501.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family GHMP_kinases_C PF08544.13 EPE29501.1 - 0.17 12.3 1.2 1.6 9.2 0.0 2.6 3 0 0 3 3 3 0 GHMP kinases C terminal DUF2974 PF11187.8 EPE29501.1 - 0.25 10.8 0.7 0.43 10.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) F-box PF00646.33 EPE29502.1 - 0.00014 21.6 0.5 0.00059 19.7 0.5 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPE29502.1 - 0.0022 17.9 0.3 0.0066 16.3 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EPE29502.1 - 0.0096 15.8 0.3 0.021 14.7 0.3 1.6 1 0 0 1 1 1 1 F-box FAD_binding_4 PF01565.23 EPE29503.1 - 6.2e-09 35.7 0.1 8.7e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DUF1279 PF06916.13 EPE29504.1 - 9.7e-11 42.1 0.1 1.3e-10 41.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Pectinesterase PF01095.19 EPE29506.1 - 1.4e-42 145.5 11.8 1.8e-42 145.1 11.8 1.1 1 0 0 1 1 1 1 Pectinesterase Glyco_hydro_28 PF00295.17 EPE29507.1 - 1.3e-117 392.5 23.8 1.5e-117 392.3 23.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Sugar_tr PF00083.24 EPE29508.1 - 3e-109 365.9 13.7 4.7e-109 365.2 13.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE29508.1 - 5.2e-26 91.4 27.5 5.2e-26 91.4 27.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPE29508.1 - 3.8e-06 25.6 2.5 6.4e-06 24.9 2.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.19 EPE29508.1 - 0.003 16.4 5.1 0.28 9.9 0.9 2.3 2 0 0 2 2 2 2 LacY proton/sugar symporter AIP3 PF03915.13 EPE29509.1 - 5e-156 519.9 9.6 5e-156 519.9 9.6 1.7 2 0 0 2 2 2 1 Actin interacting protein 3 RasGAP_C PF03836.15 EPE29509.1 - 0.0077 16.4 3.2 0.57 10.3 0.3 3.9 5 0 0 5 5 5 1 RasGAP C-terminus LsmAD PF06741.13 EPE29510.1 - 1.8e-29 102.0 1.7 4.3e-29 100.9 1.7 1.7 1 0 0 1 1 1 1 LsmAD domain DNA_binding_1 PF01035.20 EPE29511.1 - 2.4e-26 91.7 0.1 3.5e-26 91.2 0.1 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain FAD_binding_4 PF01565.23 EPE29513.1 - 3e-22 78.9 0.4 5.5e-22 78.0 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE29513.1 - 1.1e-09 38.3 0.0 2.7e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like PPI_Ypi1 PF07491.11 EPE29514.1 - 7.8e-22 76.9 0.0 2.7e-21 75.1 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase inhibitor SelP_N PF04592.14 EPE29514.1 - 0.8 9.1 5.9 1.2 8.5 5.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MFS_1 PF07690.16 EPE29515.1 - 1.7e-38 132.5 40.3 1.7e-38 132.5 40.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE29515.1 - 2.3e-11 43.2 12.0 2.3e-11 43.2 12.0 2.5 2 1 0 3 3 3 1 Sugar (and other) transporter ACOX PF01756.19 EPE29516.1 - 6.1e-45 153.0 0.3 1.3e-44 152.0 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EPE29516.1 - 4.7e-24 85.3 0.2 1.1e-23 84.2 0.2 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EPE29516.1 - 1.8e-11 44.1 0.0 4.9e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EPE29516.1 - 1.2e-05 25.6 0.0 0.091 13.0 0.0 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain RGS PF00615.19 EPE29517.1 - 6.9e-06 26.3 0.0 0.00041 20.6 0.0 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain ECF_trnsprt PF12822.7 EPE29517.1 - 0.026 14.6 2.4 0.11 12.6 1.1 2.0 2 0 0 2 2 2 0 ECF transporter, substrate-specific component Aldolase_II PF00596.21 EPE29518.1 - 4.2e-44 150.7 0.1 5.7e-44 150.3 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.16 EPE29520.1 - 7.6e-30 104.0 53.4 5.9e-26 91.2 34.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE29520.1 - 2.9e-18 66.0 24.0 2.8e-16 59.4 3.8 2.8 2 1 1 3 3 3 3 Sugar (and other) transporter SH3_9 PF14604.6 EPE29521.1 - 5.5e-13 48.6 0.0 1.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 EPE29521.1 - 1.4e-11 44.3 0.0 2.3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 EPE29521.1 - 1.5e-10 40.5 0.0 3.3e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 EPE29521.1 - 2.2e-09 37.8 0.0 1.8e-08 34.8 0.0 2.3 1 1 0 1 1 1 1 PH domain SH3_2 PF07653.17 EPE29521.1 - 0.0001 21.9 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 EPE29521.1 - 0.0027 18.1 0.0 0.0065 16.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.30 EPE29521.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_8 PF15409.6 EPE29521.1 - 0.16 12.3 0.0 0.48 10.7 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain zf-MIZ PF02891.20 EPE29522.1 - 7.5e-11 41.6 1.8 1.7e-10 40.5 1.8 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EPE29522.1 - 0.00017 21.3 0.6 0.00044 20.0 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DnaJ PF00226.31 EPE29523.1 - 4.3e-14 52.4 0.0 6.5e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain RPA43_OB PF17875.1 EPE29524.1 - 4.3e-28 98.4 6.6 6.2e-28 97.9 0.1 3.0 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EPE29524.1 - 2.3e-07 31.1 0.0 4.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GAF_2 PF13185.6 EPE29525.1 - 3.7e-10 40.2 0.0 9.8e-10 38.9 0.0 1.6 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 EPE29525.1 - 1.9e-05 25.3 0.0 2.9e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 GAF domain Arrestin_N PF00339.29 EPE29527.1 - 7.1e-16 58.6 0.1 3.3e-10 40.2 0.0 3.2 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 EPE29527.1 - 0.034 13.6 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Bul1 C terminus PDCD7 PF16021.5 EPE29528.1 - 0.21 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Programmed cell death protein 7 Las1 PF04031.13 EPE29529.1 - 4.5e-57 192.5 0.1 7.4e-57 191.8 0.1 1.4 1 0 0 1 1 1 1 Las1-like zf-RING_5 PF14634.6 EPE29530.1 - 0.0027 17.6 5.3 0.0083 16.1 5.3 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EPE29530.1 - 0.004 17.1 2.3 0.01 15.9 2.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EPE29530.1 - 0.0076 16.1 3.4 0.025 14.5 3.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE29530.1 - 0.0095 15.8 1.3 0.0095 15.8 1.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPE29530.1 - 0.022 14.6 2.5 0.07 13.0 0.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE29530.1 - 0.031 14.1 2.9 0.061 13.2 0.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 EPE29530.1 - 0.086 12.8 5.0 0.2 11.6 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 EPE29530.1 - 0.092 13.1 3.5 0.14 12.5 1.0 2.2 2 0 0 2 2 2 0 Ring finger domain zinc_ribbon_9 PF14369.6 EPE29530.1 - 0.14 12.4 0.4 0.14 12.4 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon IBR PF01485.21 EPE29530.1 - 0.39 11.0 6.8 0.072 13.3 1.9 2.0 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Lar_restr_allev PF14354.6 EPE29530.1 - 1.4 9.4 4.9 0.74 10.2 2.4 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-B_box PF00643.24 EPE29530.1 - 1.6 9.0 6.0 14 5.9 0.3 2.5 2 0 0 2 2 2 0 B-box zinc finger FYVE PF01363.21 EPE29530.1 - 1.6 8.9 6.2 9.2 6.5 6.2 2.0 1 1 0 1 1 1 0 FYVE zinc finger Prp19 PF08606.11 EPE29531.1 - 9.4e-35 118.4 1.4 2.1e-34 117.3 1.4 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 EPE29531.1 - 7e-13 48.8 1.5 0.009 16.8 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE29531.1 - 1.3e-12 47.9 0.0 0.00027 21.2 0.0 5.3 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE29531.1 - 0.00034 20.5 0.0 0.019 14.9 0.0 2.6 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A U-box PF04564.15 EPE29531.1 - 0.00057 20.0 0.0 0.0019 18.3 0.0 1.8 2 0 0 2 2 2 1 U-box domain V_ATPase_I_N PF18670.1 EPE29531.1 - 0.0044 17.4 0.1 0.0096 16.3 0.1 1.5 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain Ge1_WD40 PF16529.5 EPE29531.1 - 0.0063 15.5 0.2 0.018 14.1 0.0 1.8 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-Nse PF11789.8 EPE29531.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit OHCU_decarbox PF09349.10 EPE29532.1 - 1.2e-45 155.8 0.0 1.3e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase SnAPC_2_like PF11035.8 EPE29532.1 - 0.068 13.3 0.1 0.09 12.9 0.1 1.1 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb HILPDA PF15220.6 EPE29532.1 - 0.072 13.2 0.0 7 6.8 0.0 2.4 2 0 0 2 2 2 0 Hypoxia-inducible lipid droplet-associated LRRC37 PF15779.5 EPE29533.1 - 0.1 13.0 0.3 9.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeat-containing protein 37 family CAF1C_H4-bd PF12265.8 EPE29535.1 - 3.5e-14 52.8 1.2 1.1e-13 51.2 0.0 2.6 3 1 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EPE29535.1 - 6.6e-13 48.9 9.8 2.2e-06 28.3 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE29535.1 - 3.4e-08 33.7 1.7 0.00023 21.4 0.2 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EPE29535.1 - 0.0084 15.1 1.7 0.0084 15.1 1.7 1.8 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Ribosomal_S6 PF01250.17 EPE29536.1 - 3.4e-24 84.9 0.0 4e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Cullin_binding PF03556.15 EPE29537.1 - 2.4e-33 115.1 6.2 3.4e-33 114.6 6.2 1.2 1 0 0 1 1 1 1 Cullin binding PX PF00787.24 EPE29538.1 - 1.6e-17 63.5 0.1 3.5e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 PX domain Prefoldin_3 PF13758.6 EPE29538.1 - 0.042 13.9 3.3 0.053 13.6 0.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit APH PF01636.23 EPE29539.1 - 2e-06 27.9 0.0 4.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE29539.1 - 0.031 13.9 0.0 0.074 12.6 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase Ribosomal_L27A PF00828.19 EPE29540.1 - 4.6e-32 111.4 0.4 7e-32 110.8 0.4 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Glyco_transf_90 PF05686.12 EPE29541.1 - 7e-12 45.0 4.9 5e-10 38.9 1.4 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 IIGP PF05049.13 EPE29541.1 - 0.037 13.1 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ArAE_2_N PF10337.9 EPE29542.1 - 2.9e-47 161.8 12.5 1.9e-33 116.2 0.1 4.5 2 2 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EPE29542.1 - 3.3e-16 59.6 15.6 3.3e-16 59.6 15.6 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EPE29542.1 - 6.8e-06 26.1 0.0 0.00011 22.1 0.0 2.4 1 1 0 1 1 1 1 Aromatic acid exporter family member 2 Chs7 PF12271.8 EPE29543.1 - 2.1e-123 411.3 23.6 2.4e-123 411.1 23.6 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone MpPF26 PF07666.11 EPE29543.1 - 5.4 7.1 17.4 4.6 7.4 9.5 2.8 2 0 0 2 2 2 0 M penetrans paralogue family 26 Cyclin PF08613.11 EPE29544.1 - 6.3e-16 59.1 0.1 1e-15 58.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EPE29544.1 - 0.00031 20.5 0.0 0.00054 19.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain PGAP1 PF07819.13 EPE29545.1 - 0.00059 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EPE29545.1 - 0.00065 19.3 0.0 0.0021 17.6 0.0 1.8 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EPE29545.1 - 0.00099 19.8 2.0 0.001 19.7 0.3 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE29545.1 - 0.019 14.2 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EPE29545.1 - 0.048 13.5 0.0 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Aldedh PF00171.22 EPE29546.1 - 2e-152 508.0 0.0 2.4e-152 507.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.19 EPE29547.1 - 2.6e-53 181.3 0.0 3.8e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE29547.1 - 5e-40 137.3 0.1 8e-40 136.7 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EPE29547.1 - 0.00019 20.6 0.0 0.00028 20.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPE29547.1 - 0.00027 21.1 0.1 0.00093 19.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE29547.1 - 0.0028 17.3 0.0 0.025 14.2 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE29547.1 - 0.0042 16.4 0.0 0.011 14.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE29547.1 - 0.011 14.9 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 EPE29547.1 - 0.029 13.2 0.1 0.069 12.0 0.0 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 EPE29547.1 - 0.062 13.9 0.1 1.7 9.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase T3SS_ExsE PF18286.1 EPE29547.1 - 0.11 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Type III secretion system ExsE DUF498 PF04430.14 EPE29548.1 - 1.8e-32 111.6 0.0 2.5e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) ILVD_EDD PF00920.21 EPE29549.1 - 8.3e-211 701.1 2.5 9.6e-211 700.9 2.5 1.0 1 0 0 1 1 1 1 Dehydratase family Abhydrolase_6 PF12697.7 EPE29550.1 - 2.9e-16 60.7 0.3 6.4e-16 59.6 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE29550.1 - 3.8e-12 46.4 0.1 9.4e-11 41.8 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE29550.1 - 8.3e-10 38.3 0.0 2.5e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DSPc PF00782.20 EPE29550.1 - 1.3e-09 37.9 0.0 2.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 EPE29550.1 - 1.3e-06 28.8 0.3 3e-06 27.5 0.1 1.7 2 0 0 2 2 2 1 Thioesterase domain PTPlike_phytase PF14566.6 EPE29550.1 - 0.00022 21.4 0.0 0.00042 20.5 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Ser_hydrolase PF06821.13 EPE29550.1 - 0.0005 20.0 0.0 0.0075 16.1 0.0 2.6 3 0 0 3 3 3 1 Serine hydrolase PGAP1 PF07819.13 EPE29550.1 - 0.0018 18.0 0.8 0.015 15.1 0.8 2.1 1 1 0 1 1 1 1 PGAP1-like protein Y_phosphatase PF00102.27 EPE29550.1 - 0.0025 17.4 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Lipase_3 PF01764.25 EPE29550.1 - 0.0033 17.3 0.0 0.0071 16.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) LIDHydrolase PF10230.9 EPE29550.1 - 0.085 12.4 0.3 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 EPE29550.1 - 0.092 12.5 0.1 7.9 6.2 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EPE29550.1 - 0.22 11.0 0.0 6 6.3 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 EPE29550.1 - 0.32 10.5 1.0 2.6 7.5 0.4 2.3 2 1 0 2 2 2 0 Esterase PHB depolymerase MAP65_ASE1 PF03999.12 EPE29552.1 - 2.1e-63 215.0 51.3 6.6e-63 213.4 51.4 1.8 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF4407 PF14362.6 EPE29552.1 - 1.1 8.5 3.5 1.4 8.2 1.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) XhlA PF10779.9 EPE29552.1 - 6.3 7.1 7.9 0.41 10.9 1.3 2.5 3 0 0 3 3 3 0 Haemolysin XhlA JAB PF01398.21 EPE29553.1 - 6.3e-32 110.0 0.1 4.7e-30 104.0 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EPE29553.1 - 1.2e-24 87.0 0.2 2.3e-24 86.1 0.2 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EPE29553.1 - 0.00041 20.1 0.0 0.00085 19.1 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EPE29553.1 - 0.087 12.9 0.0 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) tRNA-synt_1c PF00749.21 EPE29554.1 - 7.5e-94 314.1 0.0 9.6e-94 313.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 EPE29554.1 - 0.043 12.7 0.0 11 4.8 0.0 2.9 3 0 0 3 3 3 0 tRNA synthetases class I (K) Ribosomal_L32e PF01655.18 EPE29555.1 - 6.7e-48 161.6 1.0 6.7e-48 161.6 1.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L32 DnaJ_C PF01556.18 EPE29555.1 - 6e-37 127.0 1.5 3e-36 124.7 0.6 2.2 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.31 EPE29555.1 - 4.3e-20 71.6 3.0 8.4e-20 70.7 3.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EPE29555.1 - 1.1e-14 54.5 18.6 2.2e-14 53.6 18.6 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EPE29555.1 - 0.03 14.3 12.7 0.31 11.0 1.7 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_10 PF16685.5 EPE29555.1 - 0.043 14.0 6.2 0.23 11.6 0.4 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 UreE_N PF02814.15 EPE29555.1 - 0.056 13.0 0.1 0.15 11.7 0.1 1.8 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain HypA PF01155.19 EPE29555.1 - 0.23 11.5 10.3 2.7 8.1 1.5 2.8 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PhnA_Zn_Ribbon PF08274.12 EPE29555.1 - 0.29 11.1 0.8 39 4.3 0.0 3.0 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DUF1356 PF07092.12 EPE29555.1 - 2.3 7.4 4.8 15 4.8 0.3 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1356) RseC_MucC PF04246.12 EPE29555.1 - 7.8 6.5 6.0 1.7 8.6 0.6 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Sec2p PF06428.11 EPE29556.1 - 5.2e-11 42.4 6.0 5.2e-11 42.4 6.0 2.3 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF4407 PF14362.6 EPE29556.1 - 0.00028 20.4 5.8 0.15 11.4 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 EPE29556.1 - 0.0055 16.9 12.2 0.058 13.6 2.9 2.2 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 DUF4795 PF16043.5 EPE29556.1 - 0.024 14.3 7.1 0.27 10.8 0.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) bZIP_1 PF00170.21 EPE29556.1 - 0.025 14.6 8.0 1.2 9.3 0.2 3.2 2 1 1 3 3 3 0 bZIP transcription factor LMBR1 PF04791.16 EPE29556.1 - 0.025 13.5 1.6 0.031 13.2 1.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FAM184 PF15665.5 EPE29556.1 - 0.033 13.9 11.6 0.14 11.9 2.3 2.2 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B SlyX PF04102.12 EPE29556.1 - 0.038 14.6 15.7 1.9 9.2 5.8 3.7 2 2 0 2 2 2 0 SlyX YlqD PF11068.8 EPE29556.1 - 0.087 13.2 11.5 1.4 9.3 2.7 2.2 2 0 0 2 2 2 0 YlqD protein V_ATPase_I PF01496.19 EPE29556.1 - 0.098 10.6 3.6 0.12 10.3 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 EPE29556.1 - 0.15 12.3 19.0 0.87 9.8 10.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.6 EPE29556.1 - 0.36 10.4 12.8 1.4 8.4 3.2 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 RasGAP_C PF03836.15 EPE29556.1 - 0.4 10.8 4.6 0.15 12.2 0.8 1.9 2 0 0 2 2 2 0 RasGAP C-terminus DUF16 PF01519.16 EPE29556.1 - 0.48 10.9 4.6 5 7.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 Spc7 PF08317.11 EPE29556.1 - 0.54 9.1 17.8 0.42 9.5 3.9 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein TACC_C PF05010.14 EPE29556.1 - 0.72 9.6 10.8 1.8 8.3 0.5 2.2 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BST2 PF16716.5 EPE29556.1 - 0.87 10.2 15.3 0.19 12.3 2.5 3.5 2 2 2 4 4 4 0 Bone marrow stromal antigen 2 FlaC_arch PF05377.11 EPE29556.1 - 0.96 9.9 3.3 33 5.0 0.0 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) YkyA PF10368.9 EPE29556.1 - 1.3 8.6 10.4 2.6 7.7 1.0 2.2 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Trimer_CC PF08954.11 EPE29556.1 - 1.9 8.1 9.1 0.31 10.6 2.6 2.8 3 0 0 3 3 3 0 Trimerisation motif YabA PF06156.13 EPE29556.1 - 2.2 9.0 5.0 2.6 8.7 0.2 2.2 2 0 0 2 2 2 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 EPE29556.1 - 2.3 8.3 19.9 0.14 12.3 3.2 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2968 PF11180.8 EPE29556.1 - 6.4 6.4 22.7 0.84 9.2 6.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Exonuc_VII_L PF02601.15 EPE29556.1 - 8 5.9 14.9 1.2e+02 2.1 14.9 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit UPRTase PF14681.6 EPE29557.1 - 5.6e-73 244.8 0.0 6.5e-73 244.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EPE29557.1 - 3.6e-05 23.3 0.1 6.9e-05 22.4 0.1 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain P5CR_dimer PF14748.6 EPE29557.1 - 0.061 13.6 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation CRCB PF02537.15 EPE29558.1 - 2.6e-37 127.0 11.6 6.5e-23 80.9 5.2 2.7 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) LRR19-TM PF15176.6 EPE29558.1 - 2.4 8.2 6.4 17 5.5 0.1 3.3 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Peptidase_S28 PF05577.12 EPE29559.1 - 2.7e-48 164.9 1.2 9.7e-48 163.0 1.2 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 EPE29559.1 - 0.061 12.0 0.0 0.13 10.9 0.0 1.5 1 0 0 1 1 1 0 PS-10 peptidase S37 Thioredoxin PF00085.20 EPE29560.1 - 6.6e-60 199.5 0.1 8.1e-29 99.7 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EPE29560.1 - 1.4e-26 93.2 2.9 4.6e-26 91.6 0.1 2.6 3 0 0 3 3 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 EPE29560.1 - 4.2e-16 59.4 0.1 1.4e-08 35.1 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EPE29560.1 - 1.9e-14 53.7 0.0 4.8e-07 29.4 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EPE29560.1 - 2.1e-13 50.2 0.0 3.3e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EPE29560.1 - 6.6e-09 36.0 0.0 0.00071 19.9 0.0 2.6 2 1 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EPE29560.1 - 1e-08 35.2 0.3 0.0023 17.9 0.0 2.3 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.6 EPE29560.1 - 3.8e-08 33.5 0.1 0.016 15.1 0.0 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain HyaE PF07449.11 EPE29560.1 - 8.9e-06 25.6 0.0 0.00054 19.9 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE ERp29_N PF07912.13 EPE29560.1 - 9.4e-06 25.8 0.2 0.0046 17.1 0.0 2.7 3 0 0 3 3 3 1 ERp29, N-terminal domain Redoxin PF08534.10 EPE29560.1 - 1.6e-05 24.7 1.6 0.023 14.4 0.0 2.3 1 1 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.6 EPE29560.1 - 2.9e-05 23.8 0.0 0.0098 15.7 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.6 EPE29560.1 - 3.6e-05 23.7 0.0 0.0014 18.5 0.0 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 EPE29560.1 - 0.00071 19.6 0.0 2.6 8.1 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin domain DSBA PF01323.20 EPE29560.1 - 0.0024 17.7 1.8 5.7 6.7 0.1 4.0 3 1 1 4 4 4 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EPE29560.1 - 0.023 14.9 4.0 4.7 7.3 0.0 3.9 3 2 2 5 5 5 0 Thioredoxin Glutaredoxin PF00462.24 EPE29560.1 - 0.049 13.8 3.2 4.5 7.6 0.3 3.2 2 2 0 2 2 2 0 Glutaredoxin HSBP1 PF06825.12 EPE29561.1 - 5.6e-19 67.7 0.2 8e-19 67.2 0.2 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 EPE29561.1 - 0.018 14.9 0.1 0.029 14.2 0.1 1.4 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin SRA1 PF07304.11 EPE29561.1 - 0.065 13.0 0.0 0.077 12.8 0.0 1.0 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) MtrB PF05440.12 EPE29561.1 - 0.21 12.0 0.3 21 5.6 0.0 2.1 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B zf-rbx1 PF12678.7 EPE29562.1 - 2e-09 37.6 0.8 3.8e-09 36.7 0.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EPE29562.1 - 8.1e-09 35.7 5.0 3.7e-08 33.6 1.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EPE29562.1 - 7.4e-07 28.9 0.6 1.2e-06 28.3 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE29562.1 - 1.1e-06 28.3 6.6 1.1e-05 25.1 2.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE29562.1 - 1.7e-06 27.9 0.6 3.2e-06 27.0 0.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EPE29562.1 - 1.6e-05 24.8 0.2 0.00016 21.6 0.0 2.6 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EPE29562.1 - 2.1e-05 24.3 1.4 4.7e-05 23.2 1.4 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EPE29562.1 - 0.00016 21.4 7.1 0.0035 17.1 0.2 3.1 3 0 0 3 3 3 2 RING-like zinc finger zf-C3HC4_3 PF13920.6 EPE29562.1 - 0.00025 20.8 1.8 0.00025 20.8 1.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2921 PF11145.8 EPE29562.1 - 0.00082 17.3 0.4 0.0012 16.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) zf-ANAPC11 PF12861.7 EPE29562.1 - 0.037 14.1 1.9 0.083 12.9 1.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EPE29562.1 - 0.045 13.4 0.8 0.1 12.2 0.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 EPE29562.1 - 0.98 9.5 3.7 11 6.1 1.2 2.5 2 0 0 2 2 2 0 Zinc-finger FANCL_C PF11793.8 EPE29562.1 - 4.3 7.6 6.0 25 5.1 6.0 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain DNA_ligase_A_M PF01068.21 EPE29563.1 - 1.3e-47 162.1 0.1 1.1e-46 159.1 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EPE29563.1 - 6.2e-43 147.1 0.0 1.2e-42 146.1 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 EPE29563.1 - 2.1e-15 57.4 0.0 4.1e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 EPE29563.1 - 5.7e-15 55.7 0.0 2e-14 53.9 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 EPE29563.1 - 1.1e-14 54.6 0.0 5.9e-09 36.2 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EPE29563.1 - 2.1e-05 24.8 0.0 0.00026 21.3 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EPE29563.1 - 0.035 14.4 0.0 1.2 9.5 0.0 2.5 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain mRNA_cap_enzyme PF01331.19 EPE29563.1 - 0.091 12.6 0.3 0.59 9.9 0.2 2.5 2 1 1 3 3 3 0 mRNA capping enzyme, catalytic domain DNA_ligase_IV PF11411.8 EPE29563.1 - 0.098 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 DNA ligase IV EF-hand_4 PF12763.7 EPE29566.1 - 0.055 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Peptidase_M28 PF04389.17 EPE29567.1 - 1.4e-24 86.9 0.4 4.3e-24 85.3 0.4 1.7 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EPE29567.1 - 1.7e-07 31.2 0.0 2.3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_C25_C PF03785.14 EPE29567.1 - 0.096 12.5 0.2 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain PTCB-BRCT PF12738.7 EPE29568.1 - 2.4e-45 152.3 0.2 3e-18 65.5 0.0 3.6 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 EPE29568.1 - 8.2e-29 99.8 0.0 8.9e-10 38.8 0.1 4.3 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EPE29568.1 - 3.1e-16 59.5 0.0 4e-07 30.4 0.0 3.9 3 0 0 3 3 3 3 BRCT domain, a BRCA1 C-terminus domain Fungal_trans PF04082.18 EPE29568.1 - 4.7e-13 48.8 0.2 1.3e-12 47.3 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain LIG3_BRCT PF16759.5 EPE29568.1 - 8.2e-05 22.8 2.6 0.16 12.3 0.0 3.8 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EPE29568.1 - 0.0002 21.4 0.5 0.38 10.9 0.0 3.0 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EPE29568.1 - 0.0064 16.4 0.0 2.2 8.2 0.0 3.4 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain Glyco_hydro_20 PF00728.22 EPE29569.1 - 1.4e-82 278.0 0.0 1.8e-82 277.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EPE29569.1 - 7.6e-28 97.9 0.1 2.7e-27 96.1 0.1 2.0 3 0 0 3 3 3 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EPE29569.1 - 6e-06 27.1 0.1 0.00029 21.6 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 p450 PF00067.22 EPE29570.1 - 1.6e-67 228.2 0.0 2.1e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.21 EPE29571.1 - 8.9e-18 64.6 0.0 1.2e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EPE29571.1 - 5.2e-05 22.2 0.0 0.00014 20.8 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 EPE29571.1 - 0.0066 15.8 0.0 0.097 12.0 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Amidase PF01425.21 EPE29572.1 - 4.2e-66 223.8 0.1 6.2e-65 219.9 0.1 2.2 1 1 0 1 1 1 1 Amidase Glutaredoxin PF00462.24 EPE29572.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin CENP-K PF11802.8 EPE29573.1 - 4.8e-07 29.6 1.9 0.19 11.3 7.0 2.5 2 1 0 2 2 2 2 Centromere-associated protein K WHEP-TRS PF00458.20 EPE29573.1 - 0.019 15.1 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 WHEP-TRS domain Fib_alpha PF08702.10 EPE29573.1 - 0.25 11.5 8.4 2.6 8.2 0.2 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family LsmAD PF06741.13 EPE29573.1 - 0.27 11.8 2.1 0.53 10.9 0.2 2.4 2 0 0 2 2 2 0 LsmAD domain DUF1664 PF07889.12 EPE29573.1 - 3 7.9 6.3 5 7.2 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 EPE29573.1 - 3.3 7.8 16.5 0.11 12.6 4.9 2.9 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain Med9 PF07544.13 EPE29573.1 - 4.9 7.3 9.7 3.4 7.8 0.3 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 MetOD2 PF18548.1 EPE29573.1 - 5.9 7.1 7.4 7.2 6.8 0.2 3.0 3 0 0 3 3 3 0 Metanogen output domain 2 DUF4709 PF15821.5 EPE29573.1 - 9.3 6.6 9.5 1.9 8.8 4.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) KH_1 PF00013.29 EPE29574.1 - 2.6e-41 139.3 5.4 1.1e-18 66.7 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EPE29574.1 - 2.2e-13 49.8 3.4 0.0017 18.1 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EPE29574.1 - 2.2e-06 27.5 0.9 0.22 11.4 0.1 3.3 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 EPE29574.1 - 0.00016 21.6 0.0 0.017 15.1 0.0 2.7 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 EPE29574.1 - 0.0018 18.3 9.0 0.21 11.7 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain Recep_L_domain PF01030.24 EPE29576.1 - 0.0025 17.9 3.4 8.7 6.5 0.0 4.0 1 1 1 3 3 3 2 Receptor L domain HIG_1_N PF04588.13 EPE29576.1 - 0.093 13.0 0.6 0.17 12.1 0.6 1.3 1 0 0 1 1 1 0 Hypoxia induced protein conserved region Ecm33 PF12454.8 EPE29576.1 - 1 9.6 8.1 0.66 10.2 1.8 2.8 2 1 1 3 3 3 0 GPI-anchored cell wall organization protein ABM PF03992.16 EPE29577.1 - 6.5e-06 26.2 0.1 0.0009 19.3 0.0 2.6 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase MSC PF09402.10 EPE29578.1 - 7.2e-111 370.9 0.1 1.1e-110 370.3 0.1 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EPE29578.1 - 1.5e-16 59.8 0.0 2.8e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 HeH/LEM domain DUF809 PF05663.11 EPE29578.1 - 2.3 8.3 5.0 6.4 6.9 4.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF809) HSP20 PF00011.21 EPE29579.1 - 9.2e-13 48.2 0.4 1.4e-12 47.6 0.4 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EPE29579.1 - 0.00028 20.4 0.5 0.00096 18.7 0.5 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA M20_dimer PF07687.14 EPE29580.1 - 7.5e-22 77.3 0.3 1.4e-21 76.4 0.3 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EPE29580.1 - 2.1e-20 73.3 1.7 2.9e-19 69.6 1.7 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EPE29580.1 - 0.005 16.6 0.1 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 ACP_syn_III_C PF08541.10 EPE29580.1 - 0.065 13.4 0.3 0.31 11.2 0.1 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal HAD PF12710.7 EPE29581.1 - 2.4e-05 24.8 0.2 0.15 12.4 0.1 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EPE29581.1 - 9e-05 22.0 0.1 0.0025 17.2 0.0 2.3 2 0 0 2 2 2 1 Putative Phosphatase HAD_2 PF13419.6 EPE29581.1 - 0.015 15.4 0.7 4.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MutS_V PF00488.21 EPE29582.1 - 6e-71 238.4 0.0 1e-70 237.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EPE29582.1 - 7.4e-44 150.3 5.4 1.4e-43 149.3 5.4 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EPE29582.1 - 3.1e-18 66.0 0.0 9.5e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EPE29582.1 - 6.9e-09 36.1 0.0 4.6e-08 33.4 0.0 2.3 1 1 0 1 1 1 1 MutS domain II Xylo_C PF12529.8 EPE29582.1 - 0.022 14.4 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 Xylosyltransferase C terminal AAA_29 PF13555.6 EPE29582.1 - 0.071 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L10 PF00466.20 EPE29583.1 - 1.9e-22 79.3 0.0 6.2e-22 77.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EPE29583.1 - 3.7e-22 78.1 0.2 9.6e-22 76.8 0.0 1.8 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EPE29583.1 - 4.5e-16 59.2 4.5 4.5e-16 59.2 4.5 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein WD40 PF00400.32 EPE29584.1 - 0.0049 17.7 0.1 8.4 7.5 0.0 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat 23S_rRNA_IVP PF05635.11 EPE29585.1 - 0.024 15.0 0.0 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein URO-D PF01208.17 EPE29586.1 - 7.8e-123 410.0 0.0 8.7e-123 409.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) dCMP_cyt_deam_1 PF00383.23 EPE29587.1 - 3.3e-21 75.1 0.0 4.3e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EPE29587.1 - 2.4e-17 63.0 0.0 2.9e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 EPE29587.1 - 0.00059 19.8 0.1 0.59 10.0 0.0 2.1 1 1 1 2 2 2 2 APOBEC-like N-terminal domain APOBEC2 PF18772.1 EPE29587.1 - 0.0012 19.0 0.3 0.12 12.4 0.3 2.1 1 1 0 1 1 1 1 APOBEC2 Bd3614-deam PF14439.6 EPE29587.1 - 0.0016 18.5 0.9 0.047 13.8 0.6 2.2 1 1 1 2 2 2 1 Bd3614-like deaminase NAD1 PF18778.1 EPE29587.1 - 0.008 16.3 0.6 0.64 10.1 0.1 2.1 1 1 0 2 2 2 1 Novel AID APOBEC clade 1 NAD2 PF18782.1 EPE29587.1 - 0.018 15.2 0.0 0.62 10.2 0.0 2.0 1 1 0 1 1 1 0 Novel AID APOBEC clade 2 SNAD4 PF18750.1 EPE29587.1 - 0.051 13.7 0.0 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 Oxysterol_BP PF01237.18 EPE29588.1 - 5.7e-52 176.8 0.0 1e-49 169.3 0.0 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein Mrx7 PF10906.8 EPE29589.1 - 3.8e-10 39.9 0.0 5.9e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 MIOREX complex component 7 Y_phosphatase PF00102.27 EPE29590.1 - 5.8e-44 150.4 0.0 8.6e-44 149.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EPE29590.1 - 0.00032 20.8 0.0 0.00075 19.5 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EPE29590.1 - 0.011 15.9 0.0 0.051 13.7 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate DSPc PF00782.20 EPE29590.1 - 0.026 14.3 0.2 0.064 13.1 0.0 1.7 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Peptidase_M28 PF04389.17 EPE29591.1 - 9.9e-37 126.5 0.0 1.4e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EPE29591.1 - 1.5e-11 44.2 0.2 3e-11 43.2 0.2 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EPE29591.1 - 0.029 14.1 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 PhzC-PhzF PF02567.16 EPE29592.1 - 2.2e-36 125.8 0.2 4.4e-35 121.5 0.2 2.0 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Frag1 PF10277.9 EPE29593.1 - 1.1e-38 133.0 9.4 1.1e-38 133.0 9.4 2.7 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family P34-Arc PF04045.14 EPE29594.1 - 4.1e-106 354.1 0.2 5.1e-106 353.8 0.2 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 EPE29594.1 - 0.083 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Radical_SAM PF04055.21 EPE29594.1 - 0.093 13.1 1.5 5.6 7.3 0.1 2.4 1 1 0 2 2 2 0 Radical SAM superfamily SF3b1 PF08920.10 EPE29596.1 - 7.5e-32 110.3 5.0 7.5e-32 110.3 5.0 2.1 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 EPE29596.1 - 1.1e-11 44.9 1.4 0.028 14.9 0.0 7.2 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 EPE29596.1 - 5.4e-10 39.5 6.6 0.61 10.5 0.0 7.7 5 3 3 8 8 8 1 HEAT repeats HEAT PF02985.22 EPE29596.1 - 4.5e-08 32.7 7.4 1.5 9.3 0.1 8.6 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.7 EPE29596.1 - 5.9e-05 23.6 0.2 1.6 9.4 0.0 5.4 6 0 0 6 6 5 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EPE29596.1 - 0.00022 20.0 0.1 0.14 10.7 0.0 3.0 3 0 0 3 3 3 2 Adaptin N terminal region DUF3385 PF11865.8 EPE29596.1 - 0.0012 18.7 1.1 0.093 12.6 0.1 4.3 6 0 0 6 6 6 1 Domain of unknown function (DUF3385) NUC173 PF08161.12 EPE29596.1 - 0.0015 18.3 0.3 1.2 8.8 0.0 4.0 2 1 1 4 4 4 1 NUC173 domain UNC45-central PF11701.8 EPE29596.1 - 0.0043 17.0 0.0 0.013 15.4 0.0 1.8 2 0 0 2 2 1 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 EPE29596.1 - 0.03 13.9 0.1 0.91 9.0 0.0 3.1 3 0 0 3 3 3 0 CLASP N terminal Dopey_N PF04118.14 EPE29596.1 - 0.033 13.3 0.4 43 3.1 0.0 4.5 5 0 0 5 5 5 0 Dopey, N-terminal Opi1 PF08618.10 EPE29596.1 - 0.092 12.0 7.0 0.24 10.6 7.0 1.7 1 0 0 1 1 1 0 Transcription factor Opi1 MMS19_C PF12460.8 EPE29596.1 - 0.1 11.7 0.0 10 5.1 0.0 3.3 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal DRIM PF07539.12 EPE29596.1 - 0.21 9.9 0.3 23 3.1 0.0 3.6 2 1 1 3 3 3 0 Down-regulated in metastasis zf-H2C2_2 PF13465.6 EPE29598.1 - 3.8e-09 36.6 17.0 2.5e-05 24.5 2.1 3.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 EPE29598.1 - 5.4e-09 36.0 14.9 2.5e-05 24.5 4.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE29598.1 - 5.7e-06 26.7 14.1 0.0014 19.2 3.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EPE29598.1 - 7.2e-06 26.2 1.3 2e-05 24.8 1.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EPE29598.1 - 0.00013 21.8 2.4 0.00013 21.8 2.4 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE29598.1 - 0.0007 19.8 4.2 0.00084 19.6 1.8 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EPE29598.1 - 0.061 13.7 1.2 0.061 13.7 1.2 1.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 EPE29598.1 - 0.62 10.0 4.5 14 5.7 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 EPE29598.1 - 0.75 9.6 10.9 3.7 7.4 2.7 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type VRR_NUC PF08774.11 EPE29599.1 - 1.9e-24 85.8 0.0 4.8e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Dpy-30 PF05186.13 EPE29600.1 - 9e-14 50.9 0.0 1.4e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif Ribosomal_S13_N PF08069.12 EPE29601.1 - 2.8e-30 104.1 0.1 4.6e-30 103.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EPE29601.1 - 1.3e-15 57.3 0.2 2e-15 56.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 EPE29601.1 - 0.034 14.1 0.1 0.082 12.8 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain HOIP-UBA PF16678.5 EPE29601.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 1 0 1 1 1 0 HOIP UBA domain pair RRM_1 PF00076.22 EPE29602.1 - 4.1e-28 97.0 0.1 4.8e-12 45.5 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPE29602.1 - 0.00015 21.6 0.0 1.1 9.2 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif OGG_N PF07934.12 EPE29603.1 - 2.3e-27 95.5 0.2 2.3e-27 95.5 0.2 1.8 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EPE29603.1 - 5.2e-15 55.8 0.0 1.1e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EPE29603.1 - 0.00016 21.3 0.0 0.00042 20.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SNase PF00565.17 EPE29604.1 - 2.8e-22 79.2 0.7 4.6e-22 78.5 0.7 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Rax2 PF12768.7 EPE29605.1 - 2.2e-69 233.2 2.5 6.7e-69 231.6 0.0 3.1 4 0 0 4 4 4 1 Cortical protein marker for cell polarity zf-RING_2 PF13639.6 EPE29606.1 - 9.8e-06 25.8 5.6 1.9e-05 24.9 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EPE29606.1 - 8.2e-05 22.8 4.6 0.00016 21.9 4.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EPE29606.1 - 0.00063 19.7 1.9 0.0012 18.8 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EPE29606.1 - 0.0007 19.4 2.5 0.0027 17.6 2.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE29606.1 - 0.0017 18.2 0.3 0.58 10.1 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EPE29606.1 - 0.0075 16.3 2.9 0.018 15.0 2.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 EPE29606.1 - 0.017 15.2 2.2 0.035 14.3 2.2 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EPE29606.1 - 0.021 15.0 1.7 0.12 12.6 1.7 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 EPE29606.1 - 0.023 14.5 0.9 0.99 9.3 0.2 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_9 PF14369.6 EPE29606.1 - 0.034 14.4 1.3 4.1 7.7 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon Sgf11 PF08209.11 EPE29606.1 - 0.054 13.1 0.5 0.054 13.1 0.5 1.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) CtsR_C PF17727.1 EPE29606.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain 7tm_2 PF00002.24 EPE29607.1 - 1.9e-07 30.6 8.5 1.9e-07 30.6 8.5 2.1 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) O-FucT PF10250.9 EPE29609.1 - 9.6e-13 48.5 0.0 6e-12 45.9 0.0 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase VSP PF03302.13 EPE29610.1 - 0.00042 19.3 1.4 0.00042 19.3 1.4 1.9 2 0 0 2 2 2 1 Giardia variant-specific surface protein TAP_C PF03943.13 EPE29611.1 - 1.2e-11 44.0 0.0 2.5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.20 EPE29611.1 - 5.3e-08 33.4 0.0 2.8e-07 31.1 0.0 2.4 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_9 PF18444.1 EPE29611.1 - 0.00064 19.5 0.0 0.0018 18.1 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif LRR_4 PF12799.7 EPE29611.1 - 0.0071 16.7 0.2 0.31 11.5 0.1 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EPE29611.1 - 0.03 13.8 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.6 EPE29611.1 - 0.035 13.9 0.1 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Leucine rich repeat COPIIcoated_ERV PF07970.12 EPE29612.1 - 1.7e-87 292.9 0.1 2.8e-87 292.2 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EPE29612.1 - 2.2e-29 101.6 0.0 6.5e-29 100.1 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sel1 PF08238.12 EPE29613.1 - 7.4e-11 42.4 6.4 0.014 16.0 0.0 4.2 4 0 0 4 4 4 3 Sel1 repeat Dynamin_N PF00350.23 EPE29614.1 - 6.9e-14 52.3 0.0 6.9e-14 52.3 0.0 4.5 2 2 1 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EPE29614.1 - 4e-07 30.1 0.1 0.00049 20.2 0.0 4.0 3 1 0 3 3 3 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EPE29614.1 - 0.00091 19.7 0.0 0.00091 19.7 0.0 3.5 3 1 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 EPE29614.1 - 0.0014 18.6 0.0 0.008 16.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase KAP_NTPase PF07693.14 EPE29614.1 - 0.0086 15.3 0.0 0.0086 15.3 0.0 3.1 3 0 0 3 3 3 1 KAP family P-loop domain AIG1 PF04548.16 EPE29614.1 - 0.028 13.7 2.4 0.062 12.6 0.0 2.6 2 0 0 2 2 2 0 AIG1 family AAA_22 PF13401.6 EPE29614.1 - 0.036 14.3 0.1 0.29 11.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EPE29614.1 - 0.044 14.1 3.2 0.1 13.0 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain AAA_18 PF13238.6 EPE29614.1 - 0.33 11.5 0.0 0.33 11.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain Sec3_C_2 PF15278.6 EPE29614.1 - 4.3 7.7 7.3 25 5.3 0.0 3.8 3 0 0 3 3 3 0 Sec3 exocyst complex subunit RabGAP-TBC PF00566.18 EPE29616.1 - 5.2e-31 108.0 0.0 4.4e-26 91.9 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Sulfate_transp PF00916.20 EPE29617.1 - 4.4e-106 354.9 21.0 5.8e-106 354.4 21.0 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EPE29617.1 - 2.7e-10 39.9 0.0 4.9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EPE29617.1 - 0.015 15.7 4.5 0.015 15.7 4.5 3.1 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily SNN_transmemb PF09049.10 EPE29617.1 - 4.4 7.3 7.5 1.2 9.1 0.9 3.0 2 0 0 2 2 2 0 Stannin transmembrane mono-CXXC PF15626.6 EPE29618.1 - 3.4 8.1 5.5 5.3 7.5 5.5 1.3 1 0 0 1 1 1 0 single CXXC unit RRN3 PF05327.11 EPE29619.1 - 5.1e-183 609.6 0.1 5.1e-183 609.6 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Retrotrans_gag PF03732.17 EPE29619.1 - 0.046 14.0 0.1 8.6 6.7 0.0 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein CBFD_NFYB_HMF PF00808.23 EPE29620.1 - 3.6e-26 91.2 1.3 6.3e-26 90.4 1.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EPE29620.1 - 7.2e-07 29.6 0.0 1.6e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EPE29620.1 - 0.0014 18.6 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EPE29620.1 - 0.0024 17.8 0.0 0.0037 17.2 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 EPE29620.1 - 0.005 16.9 0.0 0.0068 16.5 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 EPE29620.1 - 0.11 13.0 0.1 0.19 12.2 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Abhydrolase_6 PF12697.7 EPE29621.1 - 6.4e-16 59.6 0.0 7.3e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE29621.1 - 0.00013 21.3 0.1 0.0051 16.1 0.1 2.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EPE29621.1 - 0.005 16.6 0.2 0.015 15.1 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Prefoldin_2 PF01920.20 EPE29622.1 - 1.7e-24 85.8 6.5 2e-24 85.5 6.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit ALIX_LYPXL_bnd PF13949.6 EPE29622.1 - 0.0024 17.2 2.7 0.0029 17.0 2.7 1.0 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV CagS PF16707.5 EPE29622.1 - 0.0041 17.2 0.2 0.005 16.9 0.2 1.1 1 0 0 1 1 1 1 Cag pathogenicity island protein S of Helicobacter pylori GrpE PF01025.19 EPE29622.1 - 0.0053 16.4 4.0 0.84 9.3 0.1 2.0 2 0 0 2 2 2 2 GrpE FTA4 PF13093.6 EPE29622.1 - 0.0059 16.5 3.2 0.0066 16.4 3.2 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Prefoldin PF02996.17 EPE29622.1 - 0.016 15.1 6.2 2 8.4 3.4 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF1351 PF07083.11 EPE29622.1 - 0.062 13.1 5.6 0.46 10.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) DUF4795 PF16043.5 EPE29622.1 - 0.27 10.8 5.4 3.7 7.1 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Rx_N PF18052.1 EPE29622.1 - 0.42 10.9 4.0 1.6 9.0 0.9 2.1 2 0 0 2 2 2 0 Rx N-terminal domain DUF2205 PF10224.9 EPE29622.1 - 0.47 10.5 9.3 0.32 11.0 3.9 2.1 2 0 0 2 2 2 0 Short coiled-coil protein SLATT_1 PF18181.1 EPE29622.1 - 0.51 10.3 3.5 0.32 10.9 1.2 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DUF148 PF02520.17 EPE29622.1 - 0.61 10.2 8.8 2.6 8.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 Tmemb_14 PF03647.13 EPE29623.1 - 5.8e-24 84.6 7.3 6.8e-24 84.4 7.3 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DAD PF02109.16 EPE29624.1 - 1.5e-50 170.0 3.5 2.1e-50 169.6 3.5 1.1 1 0 0 1 1 1 1 DAD family DUF4389 PF14333.6 EPE29624.1 - 0.048 13.6 0.8 0.081 12.8 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) GRASP55_65 PF04495.14 EPE29625.1 - 5e-46 156.4 0.0 2.4e-44 151.0 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain UL42 PF17638.2 EPE29625.1 - 0.42 10.6 3.9 0.78 9.7 3.9 1.4 1 0 0 1 1 1 0 HCMV UL42 Methyltransf_15 PF09445.10 EPE29626.1 - 1.7e-46 157.8 0.0 2.2e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 EPE29626.1 - 9.9e-07 28.6 0.0 1.9e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 EPE29626.1 - 5.4e-06 26.2 0.0 1.1e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 EPE29626.1 - 0.00019 21.2 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.20 EPE29626.1 - 0.00064 18.9 0.0 0.0009 18.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 EPE29626.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain N6_Mtase PF02384.16 EPE29626.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_25 PF13649.6 EPE29626.1 - 0.032 14.9 0.0 0.12 13.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Nucleoporin2 PF04096.14 EPE29627.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin autopeptidase Dopey_N PF04118.14 EPE29628.1 - 1.6e-122 408.5 0.0 3.6e-120 400.7 0.0 2.6 2 1 0 2 2 2 2 Dopey, N-terminal Mon1 PF03164.14 EPE29629.1 - 8.2e-155 515.8 0.0 1e-154 515.5 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Thioredoxin PF00085.20 EPE29631.1 - 5.1e-64 212.7 2.7 2.5e-32 110.9 0.1 4.3 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 EPE29631.1 - 7.1e-47 159.7 1.2 1.9e-34 119.2 0.2 3.4 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 EPE29631.1 - 3.8e-12 45.9 1.3 9.9e-12 44.6 0.9 2.0 2 1 0 2 2 2 1 Calsequestrin Thioredoxin_7 PF13899.6 EPE29631.1 - 4.8e-09 36.3 0.0 0.0013 18.8 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EPE29631.1 - 4.7e-08 33.3 0.1 0.056 13.8 0.0 5.1 4 2 1 5 5 5 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EPE29631.1 - 6.2e-08 33.1 0.7 0.001 19.5 0.0 3.6 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EPE29631.1 - 1.7e-06 27.6 0.2 0.019 14.3 0.0 2.9 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EPE29631.1 - 3.5e-06 27.0 0.5 0.0033 17.3 0.1 3.0 2 1 1 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 EPE29631.1 - 7.5e-05 22.5 1.5 1.2 8.9 0.1 3.5 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.6 EPE29631.1 - 0.025 14.6 0.3 0.15 12.1 0.1 2.5 2 0 0 2 2 1 0 Thioredoxin domain DUF5484 PF17583.2 EPE29631.1 - 0.19 11.4 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5484) DUF883 PF05957.13 EPE29631.1 - 0.57 10.8 4.7 1.8 9.2 4.7 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) CT47 PF15623.6 EPE29631.1 - 1.9 8.3 13.1 3.6 7.4 13.1 1.4 1 0 0 1 1 1 0 Cancer/testis gene family 47 Thioredoxin_4 PF13462.6 EPE29631.1 - 3.1 7.9 10.9 13 5.9 4.4 3.7 3 1 0 3 3 3 0 Thioredoxin YtxH PF12732.7 EPE29631.1 - 9.7 6.8 8.7 25 5.5 6.9 2.8 2 1 0 2 2 2 0 YtxH-like protein DUF1664 PF07889.12 EPE29632.1 - 0.091 12.8 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-HIT PF04438.16 EPE29633.1 - 2.6e-08 33.6 9.6 3.9e-08 33.0 9.6 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF4110 PF13422.6 EPE29634.1 - 6e-30 103.2 1.8 6e-30 103.2 1.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.6 EPE29634.1 - 2.1e-28 98.0 12.6 9.8e-11 41.7 0.1 6.2 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EPE29634.1 - 3.6e-27 94.1 15.1 1.8e-09 37.5 0.0 6.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EPE29634.1 - 4.5e-18 64.8 4.6 1.1e-07 31.6 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EPE29634.1 - 1.8e-14 53.0 0.9 2e-05 24.0 0.0 5.1 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EPE29634.1 - 7.8e-14 51.0 4.6 0.0082 16.1 0.0 6.1 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 EPE29634.1 - 1.2e-13 50.8 6.6 0.00074 19.7 0.1 5.1 6 0 0 6 6 6 3 Kelch motif Abhydrolase_1 PF00561.20 EPE29635.1 - 3.7e-10 39.9 0.0 6.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE29635.1 - 1.1e-07 31.4 0.0 3e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EPE29635.1 - 0.025 14.0 0.0 0.071 12.6 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family FAD_binding_3 PF01494.19 EPE29636.1 - 1.1e-12 47.9 0.5 2.2e-11 43.6 0.2 2.4 2 1 0 2 2 2 1 FAD binding domain SE PF08491.10 EPE29636.1 - 0.00012 21.2 0.0 0.0057 15.7 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_2 PF07992.14 EPE29636.1 - 0.016 14.5 0.4 4.1 6.5 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase WLM PF08325.10 EPE29637.1 - 3.7e-29 102.2 0.2 1.4e-28 100.2 0.2 1.9 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 EPE29637.1 - 1.3e-09 38.4 0.1 2.5e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RING_10 PF16685.5 EPE29637.1 - 0.3 11.3 1.6 0.8 9.9 1.6 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Stc1 PF12898.7 EPE29637.1 - 0.31 11.6 2.6 0.77 10.4 2.6 1.7 1 0 0 1 1 1 0 Stc1 domain Zn_ribbon_17 PF17120.5 EPE29637.1 - 0.91 9.2 7.8 2.5 7.8 7.8 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 EPE29637.1 - 2.4 8.3 5.9 2.5 8.2 1.7 1.9 1 1 1 2 2 2 0 Double zinc ribbon Pkinase PF00069.25 EPE29638.1 - 6.4e-48 163.4 0.0 9.2e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE29638.1 - 1.4e-35 122.8 0.0 2.4e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPE29638.1 - 3.7e-05 22.7 0.2 0.001 17.9 0.0 2.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EPE29638.1 - 0.048 13.6 0.2 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EPE29638.1 - 0.081 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EPE29638.1 - 0.49 9.7 3.0 0.51 9.7 0.0 2.4 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Telomere_reg-2 PF10193.9 EPE29639.1 - 2.9e-33 114.6 0.0 1.4e-32 112.3 0.0 2.3 1 0 0 1 1 1 1 Telomere length regulation protein ACC_central PF08326.12 EPE29639.1 - 0.014 13.7 0.0 0.24 9.6 0.1 2.2 2 0 0 2 2 2 0 Acetyl-CoA carboxylase, central region AAA_25 PF13481.6 EPE29639.1 - 0.09 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain ThiF PF00899.21 EPE29640.1 - 5.9e-60 202.6 0.0 9.9e-60 201.9 0.0 1.3 1 1 0 1 1 1 1 ThiF family E2_bind PF08825.10 EPE29640.1 - 1.3e-29 102.2 0.0 2.2e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain Ecm33 PF12454.8 EPE29640.1 - 0.055 13.6 2.8 0.11 12.7 2.8 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Shikimate_DH PF01488.20 EPE29640.1 - 0.13 12.3 0.1 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase RNA_pol_A_bac PF01000.26 EPE29641.1 - 5.6e-25 87.9 0.0 1.5e-24 86.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EPE29641.1 - 9.4e-18 63.4 0.0 2.6e-17 62.0 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CBP_BcsQ PF06564.12 EPE29641.1 - 0.027 14.0 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Complex1_49kDa PF00346.19 EPE29642.1 - 5e-124 412.8 0.0 6.8e-124 412.3 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EPE29642.1 - 0.0071 15.3 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Nickel-dependent hydrogenase SRR1 PF07985.12 EPE29644.1 - 0.00059 19.8 0.3 0.0029 17.6 0.3 2.1 1 1 0 1 1 1 1 SRR1 F_actin_cap_B PF01115.17 EPE29645.1 - 3.9e-104 347.5 0.0 4.5e-104 347.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 EPE29645.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.7 1 1 0 1 1 1 0 F-actin capping protein alpha subunit Amino_oxidase PF01593.24 EPE29646.1 - 2.3e-80 271.1 0.3 4.8e-69 233.8 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 EPE29646.1 - 2.2e-13 50.4 0.0 4.5e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain HMG_box PF00505.19 EPE29646.1 - 5.7e-08 33.1 5.8 5.7e-08 33.1 5.8 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EPE29646.1 - 3.3e-07 30.8 9.7 7.4e-07 29.7 9.7 1.6 1 0 0 1 1 1 1 HMG-box domain NAD_binding_8 PF13450.6 EPE29646.1 - 1.9e-06 28.0 0.0 5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE29646.1 - 0.00088 18.6 0.0 0.011 15.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE29646.1 - 0.037 13.6 0.1 0.081 12.5 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase GDH_N PF12466.8 EPE29646.1 - 0.053 13.7 0.4 0.12 12.5 0.4 1.6 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal DUF4407 PF14362.6 EPE29646.1 - 0.21 10.9 2.2 0.32 10.3 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) K_oxygenase PF13434.6 EPE29646.1 - 0.23 10.5 0.5 10 5.1 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) KfrA_N PF11740.8 EPE29646.1 - 1.7 9.3 5.8 3.7 8.2 5.8 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Sec1 PF00995.23 EPE29647.1 - 2.9e-111 373.5 0.0 6e-109 365.8 0.0 2.0 1 1 0 1 1 1 1 Sec1 family tRNA-synt_His PF13393.6 EPE29648.1 - 6.3e-38 130.8 0.0 1.7e-31 109.7 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EPE29648.1 - 7.4e-13 48.5 0.0 1.7e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EPE29648.1 - 0.0016 18.5 0.0 0.0039 17.2 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 EPE29648.1 - 0.0064 15.6 0.0 0.016 14.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.7 EPE29648.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs SF-assemblin PF06705.11 EPE29648.1 - 0.093 12.1 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 SF-assemblin/beta giardin MOZART1 PF12554.8 EPE29648.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF515 PF04415.12 EPE29649.1 - 0.28 9.5 5.1 0.47 8.8 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pkinase PF00069.25 EPE29650.1 - 6.7e-68 228.9 0.0 8.7e-68 228.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE29650.1 - 2.6e-34 118.7 0.0 4.2e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE29650.1 - 2.5e-07 30.3 0.0 3.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EPE29650.1 - 0.0072 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EPE29650.1 - 0.0074 15.8 0.1 0.028 14.0 0.0 2.0 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL UQ_con PF00179.26 EPE29651.1 - 9.2e-25 86.9 0.0 1.1e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPE29651.1 - 3.9e-05 23.4 0.0 4.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EPE29651.1 - 0.0014 18.9 0.0 0.0024 18.1 0.0 1.3 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 EPE29651.1 - 0.039 13.8 0.1 0.058 13.3 0.1 1.3 1 1 0 1 1 1 0 UEV domain UFC1 PF08694.11 EPE29651.1 - 0.17 11.5 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 FAD_binding_3 PF01494.19 EPE29652.1 - 4.5e-25 88.6 0.0 7.2e-24 84.7 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EPE29652.1 - 2.6e-05 23.5 0.2 0.054 12.5 0.0 2.8 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 EPE29652.1 - 0.00023 20.8 0.0 0.59 9.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE29652.1 - 0.00056 19.2 0.0 0.008 15.4 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EPE29652.1 - 0.0023 17.0 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.6 EPE29652.1 - 0.026 14.5 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 EPE29652.1 - 0.027 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EPE29652.1 - 0.037 12.7 0.0 0.16 10.6 0.0 1.9 1 1 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EPE29652.1 - 0.043 13.0 0.0 0.091 12.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 EPE29652.1 - 0.054 13.7 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EPE29652.1 - 0.07 12.0 0.0 1.3 7.8 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Topoisom_I PF01028.20 EPE29653.1 - 6.1e-97 323.4 9.6 2.2e-96 321.6 9.6 2.0 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EPE29653.1 - 2.6e-96 321.2 4.0 2.6e-96 321.2 4.0 3.6 5 0 0 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EPE29653.1 - 7.4e-32 109.1 0.2 4.5e-31 106.6 0.2 2.5 1 0 0 1 1 1 1 C-terminal topoisomerase domain ATP-synt PF00231.19 EPE29654.1 - 3.1e-77 260.0 2.5 3.7e-77 259.8 2.5 1.0 1 0 0 1 1 1 1 ATP synthase Epimerase PF01370.21 EPE29656.1 - 1.2e-17 64.2 0.0 1.5e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EPE29656.1 - 5.1e-11 42.2 0.0 7e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EPE29656.1 - 8.3e-05 21.7 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EPE29656.1 - 0.002 17.6 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EPE29656.1 - 0.056 13.3 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 KR domain adh_short PF00106.25 EPE29656.1 - 0.11 12.0 0.0 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 EPE29656.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 EPE29656.1 - 0.2 11.8 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DLH PF01738.18 EPE29658.1 - 1.2e-20 74.0 0.1 1.6e-17 63.8 0.1 3.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EPE29658.1 - 0.023 14.2 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family BTB PF00651.31 EPE29659.1 - 0.027 14.7 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Med14 PF08638.11 EPE29660.1 - 3e-68 229.0 1.0 3.9e-68 228.6 0.1 1.7 2 0 0 2 2 2 1 Mediator complex subunit MED14 ATG22 PF11700.8 EPE29661.1 - 1.8e-199 663.3 8.2 2.1e-199 663.1 8.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EPE29661.1 - 6.8e-06 25.2 6.8 6.8e-06 25.2 6.8 3.4 2 2 1 3 3 3 2 Major Facilitator Superfamily CLN3 PF02487.17 EPE29661.1 - 0.61 9.1 6.5 0.18 10.9 0.2 2.3 2 0 0 2 2 2 0 CLN3 protein Retrotran_gag_2 PF14223.6 EPE29662.1 - 0.077 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Cwf_Cwc_15 PF04889.12 EPE29663.1 - 0.063 13.0 1.2 0.17 11.6 1.2 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RTC4 PF14474.6 EPE29664.1 - 4.2e-29 101.2 0.0 9.1e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain Dynamitin PF04912.14 EPE29665.1 - 2.1e-98 330.2 0.1 2.4e-98 330.0 0.1 1.0 1 0 0 1 1 1 1 Dynamitin Laminin_II PF06009.12 EPE29665.1 - 0.0011 18.9 1.4 0.24 11.4 0.1 3.5 3 1 1 4 4 4 1 Laminin Domain II Sipho_Gp157 PF05565.11 EPE29665.1 - 0.019 14.9 0.4 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 DUF2408 PF10303.9 EPE29665.1 - 0.15 12.6 0.7 4.3 7.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) DivIC PF04977.15 EPE29665.1 - 0.29 11.0 4.4 15 5.5 0.1 3.3 3 0 0 3 3 3 0 Septum formation initiator bZIP_Maf PF03131.17 EPE29665.1 - 0.77 10.3 6.9 1.5 9.4 2.8 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor Rx_N PF18052.1 EPE29665.1 - 0.77 10.1 5.2 1.3 9.4 0.8 3.0 3 1 0 3 3 3 0 Rx N-terminal domain APG6_N PF17675.1 EPE29665.1 - 1.6 9.3 8.9 11 6.5 2.9 2.8 2 1 0 2 2 2 0 Apg6 coiled-coil region Cwf_Cwc_15 PF04889.12 EPE29665.1 - 3.3 7.4 18.4 4.7 6.9 11.4 2.6 2 1 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Spc7 PF08317.11 EPE29665.1 - 4.5 6.1 6.0 1.3 7.9 0.9 2.3 2 1 0 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EPE29665.1 - 7.9 6.5 7.8 5.1 7.2 0.5 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein MFS_2 PF13347.6 EPE29666.1 - 2.2e-09 36.4 9.6 2.2e-09 36.4 9.6 2.3 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.7 EPE29666.1 - 4.4e-05 22.5 3.3 4.4e-05 22.5 3.3 1.8 2 1 0 2 2 2 1 MFS_1 like family DUF962 PF06127.11 EPE29666.1 - 2.4 8.3 8.7 3 8.0 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF962) UCH PF00443.29 EPE29667.1 - 8.2e-55 186.1 0.0 1.7e-54 185.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPE29667.1 - 3.1e-26 92.7 1.1 2.7e-19 69.9 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EPE29667.1 - 0.0059 16.1 4.9 0.079 12.4 1.0 2.6 2 0 0 2 2 2 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase UIM PF02809.20 EPE29667.1 - 0.021 14.7 0.4 0.056 13.4 0.4 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Tyrosinase PF00264.20 EPE29667.1 - 0.4 10.9 2.0 0.73 10.1 0.1 2.1 2 0 0 2 2 2 0 Common central domain of tyrosinase Borrelia_P83 PF05262.11 EPE29667.1 - 1.7 7.0 18.0 2.5 6.5 18.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Yos1 PF08571.10 EPE29668.1 - 2e-14 53.6 0.0 2.3e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.17 EPE29669.1 - 1.4e-41 143.2 13.5 1.8e-41 142.8 13.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1772 PF08592.11 EPE29669.1 - 1.3 9.3 10.6 0.35 11.2 1.6 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) HflK_N PF12221.8 EPE29670.1 - 0.029 14.4 0.1 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial membrane protein N terminal Integrin_b_cyt PF08725.11 EPE29670.1 - 0.038 13.7 0.2 0.089 12.5 0.2 1.5 1 0 0 1 1 1 0 Integrin beta cytoplasmic domain NT5C PF06941.12 EPE29670.1 - 0.083 12.8 1.7 0.26 11.1 0.2 2.3 1 1 2 3 3 3 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DASH_Dam1 PF08653.10 EPE29671.1 - 0.25 11.2 1.0 20 5.0 0.2 2.7 3 0 0 3 3 3 0 DASH complex subunit Dam1 adh_short PF00106.25 EPE29672.1 - 6.1e-19 68.2 0.0 1e-17 64.2 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE29672.1 - 3.6e-08 33.3 0.0 5.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE29672.1 - 1.4e-06 28.3 0.5 2.2e-06 27.7 0.5 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE29672.1 - 0.023 13.9 0.1 0.033 13.3 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Alpha-amylase PF00128.24 EPE29672.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Alpha amylase, catalytic domain SNF2_N PF00176.23 EPE29673.1 - 8.7e-51 172.7 0.0 1.3e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE29673.1 - 8.7e-16 58.3 0.1 5.2e-15 55.8 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE29673.1 - 3.9e-10 40.0 0.0 9.5e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EPE29673.1 - 5.6e-06 25.7 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HHH_3 PF12836.7 EPE29673.1 - 0.14 12.5 0.0 2.8 8.3 0.0 2.7 3 0 0 3 3 3 0 Helix-hairpin-helix motif TT_ORF2 PF02957.15 EPE29673.1 - 2.5 9.1 4.1 6.9 7.6 0.5 2.9 2 0 0 2 2 2 0 TT viral ORF2 VMA21 PF09446.10 EPE29674.1 - 3.5e-15 55.9 6.7 4.9e-15 55.4 6.7 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF2406 PF10295.9 EPE29675.1 - 8.4e-26 90.4 1.0 2e-25 89.3 1.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Ribosomal_L35Ae PF01247.18 EPE29676.1 - 2.7e-44 149.3 0.3 3e-44 149.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EPE29676.1 - 0.00095 19.3 0.0 0.53 10.5 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 EPE29676.1 - 0.28 10.9 2.0 1.6 8.5 0.4 2.5 1 1 1 2 2 2 0 Putative transposon-encoded protein (DUF2080) G6PD_C PF02781.16 EPE29677.1 - 7.4e-104 347.0 0.0 3.9e-103 344.6 0.0 1.9 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EPE29677.1 - 8e-63 212.3 0.2 1.2e-62 211.6 0.2 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.8 EPE29677.1 - 0.0007 19.3 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3226) DLH PF01738.18 EPE29678.1 - 1.5e-05 24.6 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family PRiA4_ORF3 PF07929.11 EPE29679.1 - 2.4e-15 56.7 0.0 3.2e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.18 EPE29679.1 - 4.2e-10 39.5 8.9 8.7e-10 38.5 8.9 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EPE29679.1 - 0.056 13.8 8.7 0.056 13.8 8.7 1.8 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding DUF1029 PF06269.12 EPE29681.1 - 0.037 14.1 1.9 0.058 13.5 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1029) K_trans PF02705.16 EPE29681.1 - 0.2 10.2 0.5 0.25 9.8 0.5 1.0 1 0 0 1 1 1 0 K+ potassium transporter FANCL_C PF11793.8 EPE29682.1 - 0.003 17.7 2.0 0.003 17.7 2.0 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain PHD PF00628.29 EPE29682.1 - 0.36 10.8 12.0 0.05 13.5 4.7 2.3 2 0 0 2 2 2 0 PHD-finger DUF3602 PF12223.8 EPE29683.1 - 6.8e-21 74.7 13.7 7.3e-20 71.4 6.5 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) Mito_carr PF00153.27 EPE29684.1 - 8.9e-49 163.4 8.4 3.5e-18 65.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.28 EPE29685.1 - 2.3e-06 27.9 0.1 0.4 11.2 0.0 3.4 1 1 1 2 2 2 2 CBS domain Phage_Gp23 PF10669.9 EPE29686.1 - 0.031 14.6 0.5 0.06 13.7 0.5 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Glyco_hydro_16 PF00722.21 EPE29688.1 - 5.1e-40 136.8 1.3 9.1e-40 136.0 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PP2C PF00481.21 EPE29689.1 - 5.3e-54 183.6 0.0 9.6e-54 182.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EPE29689.1 - 5.4e-39 131.8 51.6 1.3e-08 34.5 5.0 10.1 5 3 4 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 EPE29689.1 - 2.1e-30 104.3 65.2 4.4e-05 23.8 0.1 12.5 7 3 5 13 13 13 11 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EPE29689.1 - 2.6e-25 89.1 0.0 1.5e-24 86.6 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 EPE29689.1 - 3.3e-14 52.3 0.3 1e-13 50.8 0.3 1.8 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 EPE29689.1 - 6e-10 38.3 43.1 1.2 9.9 0.0 14.6 14 1 0 14 14 14 5 Leucine Rich Repeat LRR_9 PF14580.6 EPE29689.1 - 1.6e-06 27.7 18.5 0.025 14.1 1.8 5.0 2 1 2 5 5 5 5 Leucine-rich repeat IL17R_fnIII_D1 PF16556.5 EPE29689.1 - 0.033 13.8 0.0 0.52 9.9 0.0 2.3 2 0 0 2 2 2 0 Interleukin-17 receptor, fibronectin-III-like domain 1 Arrestin_C PF02752.22 EPE29690.1 - 2.3e-18 66.9 0.0 1.1e-17 64.8 0.0 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EPE29690.1 - 1.5e-05 25.1 0.3 0.13 12.3 0.0 2.6 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain zf-CCCH_2 PF14608.6 EPE29691.1 - 8.5e-18 64.1 51.0 1.2e-06 28.8 8.8 5.4 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 EPE29691.1 - 0.022 15.0 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Amino_oxidase PF01593.24 EPE29692.1 - 9.2e-29 101.0 0.0 1.2e-28 100.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPE29692.1 - 1.1e-13 51.2 0.1 2.2e-12 47.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE29692.1 - 3.8e-06 26.7 0.0 7.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase MCRA PF06100.11 EPE29692.1 - 0.015 14.1 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 MCRA family Thi4 PF01946.17 EPE29692.1 - 0.016 14.4 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 EPE29692.1 - 0.051 12.8 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE29692.1 - 0.2 12.2 0.0 0.61 10.7 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyocin_S PF06958.12 EPE29692.1 - 0.26 11.8 1.3 19 5.8 0.6 2.5 3 0 0 3 3 3 0 S-type Pyocin Peptidase_C39 PF03412.15 EPE29693.1 - 0.14 12.0 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Peptidase C39 family IBR PF01485.21 EPE29694.1 - 1.3e-10 41.3 3.3 1.3e-10 41.3 3.3 3.3 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain Bromo_TP PF07524.13 EPE29694.1 - 0.16 12.0 0.0 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Bromodomain associated Phosducin PF02114.16 EPE29695.1 - 1.7e-12 46.9 2.4 6.3e-12 45.0 0.1 2.3 2 1 0 2 2 2 1 Phosducin Citrate_bind PF16114.5 EPE29695.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding IBR PF01485.21 EPE29696.1 - 3.6e-18 65.6 32.6 7.1e-11 42.2 1.1 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain NAD_binding_8 PF13450.6 EPE29697.1 - 6.8e-14 51.8 0.2 8.5e-13 48.3 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE29697.1 - 6.2e-09 35.5 0.0 2.1e-06 27.2 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE29697.1 - 2.9e-08 33.7 0.4 5.5e-06 26.2 0.4 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPE29697.1 - 1.6e-07 30.7 1.3 3.2e-07 29.8 1.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EPE29697.1 - 2.5e-07 31.2 0.2 0.0041 17.7 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE29697.1 - 4.6e-07 29.3 0.2 9.5e-07 28.3 0.2 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EPE29697.1 - 2.2e-05 23.3 0.9 0.00018 20.4 0.8 2.0 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 EPE29697.1 - 3.9e-05 23.1 0.0 0.037 13.3 0.0 3.3 4 0 0 4 4 4 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EPE29697.1 - 0.00037 20.5 0.1 0.0019 18.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EPE29697.1 - 0.00045 19.7 0.6 0.0012 18.3 0.0 2.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPE29697.1 - 0.0011 18.4 0.4 0.0088 15.3 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EPE29697.1 - 0.0047 16.2 0.1 0.02 14.2 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EPE29697.1 - 0.0049 16.0 0.3 0.0077 15.3 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EPE29697.1 - 0.025 13.4 0.5 0.049 12.5 0.5 1.4 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 EPE29697.1 - 0.079 12.0 0.7 0.14 11.2 0.7 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 EPE29697.1 - 0.11 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EPE29697.1 - 0.13 12.5 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EPE29697.1 - 0.2 11.3 0.0 0.44 10.2 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CPBP PF02517.16 EPE29698.1 - 3.3e-16 59.4 13.9 1.1e-15 57.7 13.9 2.2 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease Synaptobrevin PF00957.21 EPE29700.1 - 0.013 15.3 0.2 0.013 15.3 0.2 2.0 2 0 0 2 2 2 0 Synaptobrevin MBOAT PF03062.19 EPE29701.1 - 1.2e-55 189.3 2.9 2.3e-55 188.4 2.9 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Sec1 PF00995.23 EPE29702.1 - 9.5e-137 457.6 0.2 1.1e-136 457.4 0.2 1.0 1 0 0 1 1 1 1 Sec1 family HEAT_2 PF13646.6 EPE29702.1 - 0.018 15.4 0.7 0.54 10.7 0.1 2.8 3 0 0 3 3 3 0 HEAT repeats Cellulase PF00150.18 EPE29703.1 - 1.5e-20 73.8 4.6 2.3e-20 73.2 4.6 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_53 PF07745.13 EPE29703.1 - 0.0019 17.3 1.9 0.0035 16.4 1.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 DER1 PF04511.15 EPE29704.1 - 2.7e-21 76.4 3.8 3.2e-21 76.1 3.8 1.0 1 0 0 1 1 1 1 Der1-like family Sacchrp_dh_C PF16653.5 EPE29705.1 - 1.3e-95 320.5 0.0 2.1e-95 319.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EPE29705.1 - 1.1e-24 87.2 0.1 1.9e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EPE29705.1 - 6.9e-07 29.3 0.3 4.5e-05 23.4 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 EPE29705.1 - 4.4e-06 26.8 0.0 1.1e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 EPE29705.1 - 0.00032 20.3 0.4 0.0056 16.3 0.0 2.7 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 EPE29705.1 - 0.021 14.1 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 EPE29705.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.22 EPE29705.1 - 0.17 12.7 0.1 0.43 11.4 0.1 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold CN_hydrolase PF00795.22 EPE29706.1 - 8.7e-12 44.9 0.0 3.1e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Glyco_hydro_61 PF03443.14 EPE29707.1 - 2.7e-65 220.2 0.2 3.3e-65 219.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ABC_tran PF00005.27 EPE29708.1 - 7.1e-38 130.2 0.0 1.2e-17 64.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPE29708.1 - 8e-27 94.6 24.3 8e-26 91.3 12.3 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EPE29708.1 - 7.6e-12 45.1 1.2 0.00073 19.0 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EPE29708.1 - 2e-08 34.4 6.6 0.45 10.3 0.0 4.4 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EPE29708.1 - 7.3e-08 32.0 0.2 0.0073 16.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EPE29708.1 - 4.7e-07 30.2 0.0 0.064 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EPE29708.1 - 9.8e-07 28.9 0.1 0.05 13.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 EPE29708.1 - 5.4e-06 25.7 0.1 0.0016 17.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 EPE29708.1 - 8.7e-06 26.2 0.3 0.16 12.4 0.0 3.5 4 0 0 4 4 3 2 AAA ATPase domain Dynamin_N PF00350.23 EPE29708.1 - 3e-05 24.2 0.1 0.024 14.7 0.1 2.4 2 0 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 EPE29708.1 - 3.7e-05 23.7 0.4 0.13 12.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EPE29708.1 - 0.00014 22.4 1.3 0.48 10.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EPE29708.1 - 0.00018 21.7 0.6 0.0095 16.1 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_18 PF13238.6 EPE29708.1 - 0.00024 21.7 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EPE29708.1 - 0.00037 20.1 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EPE29708.1 - 0.00048 19.6 0.1 0.87 8.9 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA PF00004.29 EPE29708.1 - 0.0005 20.5 0.0 2.3 8.6 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EPE29708.1 - 0.0027 17.5 1.6 0.99 9.0 0.2 2.2 2 0 0 2 2 2 2 AAA ATPase domain ATP_bind_1 PF03029.17 EPE29708.1 - 0.0028 17.5 0.1 0.05 13.4 0.1 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 EPE29708.1 - 0.0084 16.3 1.6 6.6 7.0 0.4 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EPE29708.1 - 0.0092 16.1 0.0 1.3 9.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EPE29708.1 - 0.011 16.2 0.1 4.6 7.7 0.0 3.0 3 0 0 3 3 3 0 RNA helicase IIGP PF05049.13 EPE29708.1 - 0.037 13.1 0.1 4.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_25 PF13481.6 EPE29708.1 - 0.045 13.3 0.1 3 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EPE29708.1 - 0.068 12.9 0.0 29 4.3 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EPE29708.1 - 0.096 12.4 0.5 16 5.2 0.0 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_24 PF13479.6 EPE29708.1 - 0.14 11.9 0.1 16 5.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EPE29708.1 - 0.15 12.0 0.2 34 4.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.7 EPE29708.1 - 0.16 10.9 0.1 3.7 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Mg_chelatase PF01078.21 EPE29708.1 - 0.19 11.1 0.4 16 4.8 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI CLP1_P PF16575.5 EPE29708.1 - 0.31 10.8 1.2 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PepSY_TM PF03929.16 EPE29709.1 - 0.063 12.9 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 PepSY-associated TM region TPR_10 PF13374.6 EPE29710.1 - 0.0073 16.2 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Mid2 PF04478.12 EPE29711.1 - 0.0047 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 EPE29711.1 - 0.042 13.6 0.5 0.074 12.8 0.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 EPE29711.1 - 0.11 11.9 0.2 0.22 10.9 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-C2H2 PF00096.26 EPE29713.1 - 0.0082 16.5 23.6 0.012 16.1 1.3 5.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPE29713.1 - 0.015 15.7 0.3 0.015 15.7 0.3 3.1 2 0 0 2 2 2 0 Zinc-finger double domain ARA70 PF12489.8 EPE29713.1 - 0.028 14.6 1.2 0.076 13.2 1.2 1.7 1 0 0 1 1 1 0 Nuclear coactivator RRM_1 PF00076.22 EPE29713.1 - 0.037 13.8 0.0 0.095 12.5 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.6 EPE29713.1 - 0.098 13.6 19.3 0.15 13.0 0.9 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger DUF2408 PF10303.9 EPE29713.1 - 0.3 11.6 4.3 0.18 12.3 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) zf-CHCC PF10276.9 EPE29713.1 - 0.87 9.7 4.2 15 5.8 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger domain FliD_N PF02465.18 EPE29713.1 - 2.9 8.6 8.7 15 6.4 0.0 3.5 3 1 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DKCLD PF08068.12 EPE29714.1 - 1e-32 112.0 0.4 3.7e-31 107.0 0.3 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 EPE29714.1 - 2.9e-23 82.9 0.2 3e-20 73.1 0.2 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EPE29714.1 - 8.5e-22 77.1 1.0 1.6e-21 76.2 1.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 EPE29714.1 - 2.6e-21 75.3 1.2 5.3e-21 74.4 1.2 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EPE29714.1 - 0.00094 19.4 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain AP3D1 PF06375.11 EPE29714.1 - 0.066 13.4 11.8 0.1 12.9 11.8 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Med19 PF10278.9 EPE29714.1 - 2.3 8.1 12.2 3.2 7.7 11.4 1.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Spo12 PF05032.12 EPE29715.1 - 5.8e-16 58.1 3.1 1.1e-15 57.2 3.1 1.5 1 0 0 1 1 1 1 Spo12 family DUF4871 PF16167.5 EPE29715.1 - 0.049 13.6 0.1 0.061 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4871) Acyl-CoA_dh_1 PF00441.24 EPE29716.1 - 6.2e-30 104.4 0.2 1.3e-29 103.4 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EPE29716.1 - 2.8e-20 72.3 0.0 5e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EPE29716.1 - 3.4e-15 56.7 0.0 6.8e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EPE29716.1 - 1.5e-13 51.2 0.4 2.7e-13 50.4 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MMR_HSR1 PF01926.23 EPE29718.1 - 3.7e-16 59.2 0.2 6.1e-15 55.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPE29718.1 - 3.2e-07 30.0 0.3 7.4e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EPE29718.1 - 4.1e-07 30.0 0.0 0.00054 19.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 EPE29718.1 - 0.0067 15.8 0.1 0.012 14.9 0.1 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EPE29718.1 - 0.031 14.3 4.5 0.077 13.0 0.1 3.1 3 0 0 3 3 3 0 Dynamin family MeaB PF03308.16 EPE29718.1 - 0.11 11.5 0.0 0.37 9.7 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB LTV PF04180.14 EPE29719.1 - 1.8e-132 442.7 17.0 2.1e-132 442.5 17.0 1.0 1 0 0 1 1 1 1 Low temperature viability protein SAC3_GANP PF03399.16 EPE29720.1 - 8e-97 324.1 0.2 1.1e-96 323.6 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EPE29720.1 - 0.0094 15.9 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Tmemb_cc2 PF10267.9 EPE29720.1 - 0.94 8.5 4.4 3 6.9 4.4 1.8 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MMR_HSR1_Xtn PF16897.5 EPE29721.1 - 2.8e-35 120.5 2.7 4.2e-35 120.0 0.9 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EPE29721.1 - 2.9e-20 72.5 0.0 6.2e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EPE29721.1 - 1.1e-19 70.2 0.1 2.2e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EPE29721.1 - 5.8e-13 48.7 0.0 9.1e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EPE29721.1 - 0.00048 20.2 0.2 1.1 9.3 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MCM PF00493.23 EPE29721.1 - 0.088 11.9 0.1 0.29 10.2 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain MeaB PF03308.16 EPE29721.1 - 0.096 11.7 0.1 0.19 10.7 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DNA_pol_B PF00136.21 EPE29722.1 - 1.5e-112 376.6 1.8 2.2e-112 376.1 1.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EPE29722.1 - 1.6e-68 230.1 5.1 3.2e-68 229.1 5.1 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EPE29722.1 - 1.3e-42 146.1 0.0 3.1e-42 144.9 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EPE29722.1 - 8.6e-22 77.0 16.7 8.1e-21 73.9 11.1 3.0 2 0 0 2 2 2 2 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EPE29722.1 - 0.0087 15.0 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral RRP7 PF12923.7 EPE29722.1 - 0.038 14.1 5.0 0.13 12.4 5.0 1.9 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain YL1 PF05764.13 EPE29722.1 - 7.1 6.7 12.4 20 5.2 12.4 1.8 1 0 0 1 1 1 0 YL1 nuclear protein PPR_2 PF13041.6 EPE29723.1 - 5e-29 100.3 0.9 1.3e-17 63.7 0.0 3.0 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 EPE29723.1 - 3.6e-11 43.0 0.1 0.00028 20.9 0.0 2.6 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 EPE29723.1 - 3.9e-11 42.4 2.1 0.00047 20.2 0.1 4.8 4 0 0 4 4 4 3 PPR repeat PPR_long PF17177.4 EPE29723.1 - 1.5e-09 37.5 0.0 1.5e-09 37.5 0.0 2.8 4 0 0 4 4 4 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EPE29723.1 - 7.6e-08 31.9 1.1 0.77 9.5 0.0 4.6 4 0 0 4 4 4 4 PPR repeat RRM_1 PF00076.22 EPE29725.1 - 9.1e-07 28.6 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRI PF15325.6 EPE29725.1 - 0.58 11.3 2.9 0.93 10.6 0.6 2.2 2 0 0 2 2 2 0 Modulator of retrovirus infection MIF4G PF02854.19 EPE29726.1 - 4.1e-52 176.9 0.0 6.3e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 EPE29726.1 - 8.7e-23 80.3 0.9 3.1e-22 78.5 0.9 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Pkinase PF00069.25 EPE29727.1 - 2e-50 171.6 0.1 8.8e-50 169.5 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE29727.1 - 2.6e-23 82.6 0.0 5.2e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPE29727.1 - 0.0005 20.1 1.6 0.00052 20.0 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EPE29727.1 - 0.0035 17.0 0.2 0.0087 15.7 0.2 1.6 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EPE29727.1 - 0.15 11.7 0.2 0.34 10.5 0.2 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase SNF2_N PF00176.23 EPE29728.1 - 7.9e-64 215.6 0.0 2e-63 214.3 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE29728.1 - 4.8e-20 72.0 0.1 1.8e-19 70.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE29728.1 - 1.8e-05 24.8 0.0 5.7e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EPE29728.1 - 0.00033 20.0 0.0 0.00071 18.9 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF724 PF05266.14 EPE29728.1 - 2 8.2 5.9 5.3 6.8 5.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ABC_tran_CTD PF16326.5 EPE29728.1 - 7.7 6.9 9.4 3.3 8.0 0.3 3.1 2 1 0 3 3 3 0 ABC transporter C-terminal domain LON_substr_bdg PF02190.16 EPE29730.1 - 3e-29 102.4 0.0 4.4e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EPE29730.1 - 2.9e-11 43.0 10.8 6.3e-11 41.9 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPE29730.1 - 6.8e-10 38.7 6.2 1.8e-09 37.3 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE29730.1 - 1.2e-07 31.7 12.0 8.5e-07 28.9 6.6 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EPE29730.1 - 7.3e-07 29.0 9.0 1.6e-06 27.9 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE29730.1 - 9.8e-07 28.6 8.7 9.8e-07 28.6 8.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EPE29730.1 - 1.3e-06 28.6 10.1 1.3e-06 28.6 10.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 EPE29730.1 - 5.1e-06 26.5 6.4 5.1e-06 26.5 6.4 2.7 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EPE29730.1 - 2.9e-05 23.9 8.0 2.9e-05 23.9 8.0 1.7 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EPE29730.1 - 5.1e-05 23.0 1.9 0.00018 21.2 1.9 2.0 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EPE29730.1 - 0.0036 17.4 5.4 0.0067 16.5 5.4 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-P11 PF03854.14 EPE29730.1 - 0.0041 16.7 6.0 0.0084 15.7 6.0 1.5 1 0 0 1 1 1 1 P-11 zinc finger zf-rbx1 PF12678.7 EPE29730.1 - 0.018 15.3 5.3 0.018 15.3 5.3 1.8 2 0 0 2 2 1 0 RING-H2 zinc finger domain DZR PF12773.7 EPE29730.1 - 0.053 13.6 0.3 0.053 13.6 0.3 1.8 1 1 0 1 1 1 0 Double zinc ribbon U-box PF04564.15 EPE29730.1 - 0.11 12.7 0.1 0.29 11.3 0.1 1.7 1 0 0 1 1 1 0 U-box domain MTHFR_C PF12225.8 EPE29730.1 - 2.1 8.0 5.0 1.6 8.5 0.0 2.5 2 1 1 3 3 3 0 Methylene-tetrahydrofolate reductase C terminal zf-Nse PF11789.8 EPE29730.1 - 3.4 7.5 7.7 2.8 7.8 4.0 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RecR PF02132.15 EPE29730.1 - 4.9 6.8 7.7 7.2 6.3 2.7 2.9 3 0 0 3 3 3 0 RecR protein 3HCDH_N PF02737.18 EPE29731.1 - 1.9e-51 174.5 0.9 2.4e-51 174.2 0.9 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EPE29731.1 - 2.4e-33 114.6 0.0 5.1e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 EPE29731.1 - 5.4e-05 23.5 0.1 0.00011 22.5 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 EPE29731.1 - 8.7e-05 22.7 0.2 0.00024 21.3 0.1 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 EPE29731.1 - 0.012 15.2 0.6 0.024 14.2 0.4 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EPE29731.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 EPE29731.1 - 0.025 14.2 0.7 0.038 13.6 0.7 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE29731.1 - 0.041 13.1 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_32 PF13679.6 EPE29731.1 - 0.12 12.3 0.1 0.2 11.7 0.1 1.4 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox PF00070.27 EPE29731.1 - 0.16 12.6 0.1 0.6 10.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TIMELESS PF04821.14 EPE29732.1 - 8.7e-88 294.2 0.0 1.9e-87 293.1 0.0 1.6 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 EPE29732.1 - 8.4e-35 120.9 23.4 8.4e-35 120.9 23.4 3.8 2 1 0 2 2 2 1 Timeless protein C terminal region Arg_repressor_C PF02863.18 EPE29732.1 - 0.079 12.8 0.1 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain FR47 PF08445.10 EPE29733.1 - 0.00061 19.7 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Homeodomain PF00046.29 EPE29734.1 - 4e-17 61.8 4.4 7.2e-17 61.0 3.4 1.9 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 EPE29734.1 - 0.067 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain Sigma70_ner PF04546.13 EPE29734.1 - 0.23 11.3 4.2 0.41 10.5 4.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4632 PF15451.6 EPE29734.1 - 0.26 11.4 2.7 0.38 10.9 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) PGA2 PF07543.12 EPE29734.1 - 4.7 7.2 9.9 0.37 10.8 2.9 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 Aquarius_N PF16399.5 EPE29735.1 - 0 1133.1 0.0 0 1132.8 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 EPE29735.1 - 1.1e-26 93.7 0.0 1.9e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EPE29735.1 - 5.6e-20 72.2 0.0 3.1e-19 69.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPE29735.1 - 4.4e-06 26.5 0.0 0.0027 17.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 EPE29735.1 - 1e-05 25.6 0.0 2.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EPE29735.1 - 6.8e-05 23.2 0.0 0.00019 21.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EPE29735.1 - 0.0013 19.1 0.0 0.0048 17.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 EPE29735.1 - 0.0014 18.0 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Viral_helicase1 PF01443.18 EPE29735.1 - 0.0016 18.2 0.1 0.075 12.8 0.0 2.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EPE29735.1 - 0.0036 17.7 0.0 0.015 15.7 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 EPE29735.1 - 0.0045 16.8 0.4 0.011 15.5 0.2 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.9 EPE29735.1 - 0.013 14.8 1.1 0.023 14.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EPE29735.1 - 0.017 15.4 0.1 0.13 12.5 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 EPE29735.1 - 0.054 13.5 0.0 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.17 EPE29735.1 - 0.061 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EPE29735.1 - 0.081 12.5 0.0 0.28 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain efThoc1 PF11957.8 EPE29736.1 - 2.3e-140 468.6 2.7 2.3e-140 468.6 2.7 1.5 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 EPE29736.1 - 1.7e-46 158.2 0.1 1.7e-46 158.2 0.1 1.8 2 0 0 2 2 2 1 Guanylate kinase RsgA_GTPase PF03193.16 EPE29736.1 - 2.8e-07 30.6 0.0 6.5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EPE29736.1 - 9.1e-06 25.7 0.0 2.5e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EPE29736.1 - 0.00022 21.8 0.0 0.00074 20.0 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 EPE29736.1 - 0.00026 21.6 2.1 0.00042 20.9 0.0 2.5 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPE29736.1 - 0.00027 21.2 0.0 0.0011 19.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EPE29736.1 - 0.00042 20.3 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EPE29736.1 - 0.0022 18.4 0.0 0.0086 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EPE29736.1 - 0.0027 17.4 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EPE29736.1 - 0.0027 17.9 0.1 0.089 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EPE29736.1 - 0.0045 16.7 0.5 0.034 13.9 0.5 2.4 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 EPE29736.1 - 0.0091 15.3 0.3 0.026 13.8 0.0 1.8 2 0 0 2 2 2 1 Septin T2SSE PF00437.20 EPE29736.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EPE29736.1 - 0.047 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EPE29736.1 - 0.052 13.6 0.3 0.32 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EPE29736.1 - 0.062 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EPE29736.1 - 0.073 12.8 0.0 0.27 10.9 0.0 2.0 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EPE29736.1 - 0.095 12.6 0.1 0.29 11.0 0.1 1.8 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 EPE29736.1 - 0.1 12.5 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 NTPase DUF3987 PF13148.6 EPE29736.1 - 0.73 8.8 0.0 0.73 8.8 0.0 2.8 4 0 0 4 4 3 0 Protein of unknown function (DUF3987) AAA_23 PF13476.6 EPE29736.1 - 1.1 9.7 5.8 6.4 7.2 3.1 2.8 2 1 0 2 2 2 0 AAA domain Oxidored_FMN PF00724.20 EPE29737.1 - 5.5e-72 242.9 0.0 7.5e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 EPE29737.1 - 0.2 11.4 0.0 0.3 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Polysacc_deac_1 PF01522.21 EPE29739.1 - 2.7e-15 56.4 0.0 6.3e-15 55.2 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide deacetylase Methyltransf_PK PF05891.12 EPE29740.1 - 2.3e-77 259.4 0.0 2.6e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EPE29740.1 - 0.01 16.5 0.0 0.023 15.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EPE29740.1 - 0.018 14.9 0.0 0.033 14.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EPE29740.1 - 0.022 14.1 0.1 0.036 13.4 0.0 1.4 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_11 PF08241.12 EPE29740.1 - 0.027 15.1 0.0 0.046 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GDP_Man_Dehyd PF16363.5 EPE29742.1 - 4.2e-69 233.5 0.0 5e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EPE29742.1 - 5.1e-57 193.1 0.0 6.5e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EPE29742.1 - 2.4e-23 82.7 0.0 2.7e-22 79.3 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EPE29742.1 - 7.4e-20 71.1 0.0 1.1e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EPE29742.1 - 2.1e-19 69.7 0.2 2.9e-18 66.0 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 EPE29742.1 - 7.5e-18 64.6 0.0 1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EPE29742.1 - 7.8e-07 29.2 0.0 4e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 EPE29742.1 - 0.055 12.9 0.0 1.9 7.9 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase MMS1_N PF10433.9 EPE29743.1 - 1.3e-162 541.8 0.0 2.4e-162 541.0 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EPE29743.1 - 4.3e-99 331.9 0.0 6.3e-98 328.0 0.0 2.4 2 0 0 2 2 2 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 EPE29743.1 - 0.034 14.5 0.0 1.8 8.9 0.0 3.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain LysM PF01476.20 EPE29744.1 - 8.8e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 LysM domain Prok-RING_4 PF14447.6 EPE29744.1 - 0.0015 18.3 8.7 0.0031 17.4 8.5 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EPE29744.1 - 0.34 10.9 9.1 1.1 9.3 9.1 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EPE29744.1 - 0.74 10.2 9.4 0.074 13.4 4.8 1.7 2 0 0 2 2 2 0 Ring finger domain FYVE PF01363.21 EPE29744.1 - 0.77 9.9 5.9 1.7 8.8 5.9 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_3 PF13920.6 EPE29744.1 - 0.79 9.6 8.7 1.1 9.1 5.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) His_Phos_2 PF00328.22 EPE29745.1 - 3.6e-17 62.8 0.0 1.7e-15 57.3 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF5427 PF10310.9 EPE29745.1 - 0.13 11.2 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Ribosomal_L5e PF17144.4 EPE29746.1 - 2e-81 271.8 0.4 3.3e-81 271.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EPE29746.1 - 3.6e-32 111.1 8.3 3.6e-32 111.1 8.3 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region LRR_6 PF13516.6 EPE29747.1 - 0.0014 18.5 8.6 1.2 9.4 0.0 5.7 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 EPE29747.1 - 0.053 14.0 1.8 16 6.1 0.2 3.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) MDMPI_N PF11716.8 EPE29747.1 - 0.4 11.3 1.9 0.52 11.0 0.2 2.1 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Egh16-like PF11327.8 EPE29751.1 - 5.1e-68 229.1 9.0 7.6e-68 228.5 9.0 1.3 1 0 0 1 1 1 1 Egh16-like virulence factor HET PF06985.11 EPE29752.1 - 4.4e-27 95.2 0.0 1.1e-26 93.9 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_4 PF13637.6 EPE29753.1 - 0.0069 16.9 0.0 0.017 15.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE29753.1 - 0.012 16.2 0.0 0.038 14.6 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE29753.1 - 0.058 14.0 0.1 11 6.9 0.0 3.1 2 0 0 2 2 2 0 Ankyrin repeat CENP-X PF09415.10 EPE29753.1 - 0.087 13.2 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X NACHT PF05729.12 EPE29754.1 - 0.0001 22.3 0.0 0.00027 20.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Goodbye PF17109.5 EPE29754.1 - 0.0042 17.5 0.5 0.009 16.5 0.0 1.9 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain PDCD7 PF16021.5 EPE29754.1 - 0.017 14.3 4.1 0.026 13.7 4.1 1.2 1 0 0 1 1 1 0 Programmed cell death protein 7 fn3 PF00041.21 EPE29755.1 - 5.2e-06 26.7 0.0 1.5e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Bombinin PF05298.11 EPE29755.1 - 0.14 11.8 2.7 0.32 10.7 2.7 1.6 1 0 0 1 1 1 0 Bombinin COesterase PF00135.28 EPE29756.1 - 7.9e-76 256.0 0.0 1e-75 255.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE29756.1 - 0.00016 21.6 0.0 0.00068 19.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold ERO1 PF04137.15 EPE29757.1 - 1.2e-136 455.6 0.0 1.4e-136 455.3 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Defb50 PF17546.2 EPE29757.1 - 0.37 10.7 6.7 6.5 6.7 1.3 3.0 3 0 0 3 3 3 0 Beta defensin 50 CKS PF01111.19 EPE29758.1 - 3.9e-35 119.9 1.8 4.9e-35 119.6 1.8 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.25 EPE29759.1 - 1.1e-34 118.4 2.3 1.9e-17 63.1 0.1 2.4 2 0 0 2 2 2 2 Bromodomain HSP70 PF00012.20 EPE29760.1 - 7.3e-224 744.4 9.6 8.2e-224 744.2 9.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EPE29760.1 - 6e-16 58.2 0.2 5e-15 55.2 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EPE29760.1 - 9.3e-05 22.2 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain RRF PF01765.19 EPE29761.1 - 1.2e-38 132.6 2.8 1.6e-38 132.2 2.8 1.2 1 0 0 1 1 1 1 Ribosome recycling factor Guanylate_kin PF00625.21 EPE29761.1 - 0.004 16.9 0.2 0.4 10.3 0.1 2.4 2 1 0 2 2 2 2 Guanylate kinase Methyltrans_RNA PF04452.14 EPE29761.1 - 0.006 16.0 0.0 1.1 8.5 0.0 2.6 2 1 0 2 2 2 2 RNA methyltransferase CDC73_N PF16050.5 EPE29761.1 - 0.013 14.9 0.7 0.025 13.9 0.7 1.4 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal FadR_C PF07840.12 EPE29762.1 - 0.071 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 FadR C-terminal domain ANAPC_CDC26 PF10471.9 EPE29763.1 - 5.2e-19 68.8 5.0 8e-19 68.3 5.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Spo12 PF05032.12 EPE29763.1 - 0.1 12.5 3.0 5.8 6.9 0.2 2.4 2 0 0 2 2 2 0 Spo12 family Peptidase_M1_N PF17900.1 EPE29764.1 - 2.5e-05 24.5 0.0 0.057 13.6 0.0 2.6 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 EPE29764.1 - 0.0041 16.7 0.0 0.0093 15.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain SAS4 PF15460.6 EPE29765.1 - 4.5e-33 113.3 2.5 4.5e-33 113.3 2.5 1.9 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.6 EPE29765.1 - 0.0016 19.1 0.3 0.0016 19.1 0.3 4.2 3 2 2 5 5 5 1 PEHE domain Adaptin_binding PF10199.9 EPE29765.1 - 0.022 15.3 0.9 0.022 15.3 0.9 2.8 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Response_reg PF00072.24 EPE29766.1 - 7.7e-22 77.6 0.5 1.8e-21 76.4 0.5 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EPE29766.1 - 4.4e-20 72.3 0.0 9.3e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EPE29766.1 - 2.6e-08 33.8 0.3 7.3e-08 32.3 0.3 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EPE29766.1 - 3.9e-06 27.1 0.0 7.6e-05 22.9 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EPE29766.1 - 1.2e-05 25.3 0.0 0.00017 21.5 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 EPE29766.1 - 0.00025 21.3 0.1 0.00052 20.2 0.1 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EPE29766.1 - 0.00058 20.1 0.0 0.088 13.1 0.0 2.9 2 0 0 2 2 2 1 PAS fold GAF_2 PF13185.6 EPE29766.1 - 0.1 12.9 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 GAF domain Thioredoxin_4 PF13462.6 EPE29767.1 - 0.0015 18.7 0.0 0.0088 16.2 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EPE29767.1 - 0.018 14.8 0.0 0.056 13.2 0.0 1.7 2 0 0 2 2 2 0 DSBA-like thioredoxin domain SKG6 PF08693.10 EPE29768.1 - 3.2e-11 42.4 0.1 3.2e-11 42.4 0.1 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain INO80_Ies4 PF08193.11 EPE29768.1 - 0.004 17.2 3.1 0.0051 16.8 3.1 1.2 1 0 0 1 1 1 1 INO80 complex subunit Ies4 ORC6 PF05460.13 EPE29768.1 - 0.026 13.8 1.9 0.034 13.4 1.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FSA_C PF10479.9 EPE29768.1 - 0.049 11.8 7.8 0.066 11.4 7.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SOG2 PF10428.9 EPE29768.1 - 0.44 9.7 12.6 0.7 9.0 12.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Podoplanin PF05808.11 EPE29768.1 - 0.64 10.1 7.1 1.3 9.1 7.0 1.4 1 1 0 1 1 1 0 Podoplanin ATF7IP_BD PF16788.5 EPE29768.1 - 8.8 6.4 9.8 13 5.9 9.8 1.1 1 0 0 1 1 1 0 ATF-interacting protein binding domain Pkinase PF00069.25 EPE29769.1 - 1.4e-17 64.0 0.0 2.1e-16 60.1 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain PX PF00787.24 EPE29769.1 - 1.1e-12 48.0 0.0 2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 PX domain Pkinase_Tyr PF07714.17 EPE29769.1 - 0.0089 15.3 0.0 0.11 11.8 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase CDP-OH_P_transf PF01066.21 EPE29771.1 - 1.9e-15 57.4 0.1 1.9e-15 57.4 0.1 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GRAB PF10375.9 EPE29771.1 - 0.07 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 GRIP-related Arf-binding domain DUF724 PF05266.14 EPE29772.1 - 1.6 8.6 7.9 0.1 12.4 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DctQ PF04290.12 EPE29773.1 - 0.018 15.0 0.0 0.02 14.8 0.0 1.0 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF3611 PF12263.8 EPE29773.1 - 0.029 14.3 0.1 0.033 14.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) MMM1 PF10296.9 EPE29777.1 - 4.9e-08 32.4 0.0 1.1e-07 31.2 0.0 1.5 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 VPS28 PF03997.12 EPE29778.1 - 6.7e-69 231.4 0.1 7.9e-69 231.1 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein Fungal_trans PF04082.18 EPE29780.1 - 1.5e-19 70.1 0.0 2.5e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE29780.1 - 5.7e-08 32.8 13.7 1.4e-07 31.5 13.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5094 PF17015.5 EPE29780.1 - 0.017 15.2 2.5 0.026 14.6 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) TSC22 PF01166.18 EPE29780.1 - 0.063 13.6 0.4 0.14 12.5 0.4 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 EPE29780.1 - 0.13 12.1 0.9 0.24 11.3 0.9 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Jnk-SapK_ap_N PF09744.9 EPE29780.1 - 0.37 11.0 4.7 0.57 10.4 4.7 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 RE_NgoFVII PF09565.10 EPE29780.1 - 0.47 9.7 1.8 0.72 9.1 1.8 1.1 1 0 0 1 1 1 0 NgoFVII restriction endonuclease Nha1_C PF08619.10 EPE29781.1 - 5.9e-106 355.5 53.0 4.3e-103 346.0 35.2 2.1 2 0 0 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 EPE29781.1 - 2e-77 260.5 20.2 2.7e-77 260.1 20.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family p450 PF00067.22 EPE29781.1 - 7.3e-45 153.6 0.0 1.2e-44 152.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 YrhC PF14143.6 EPE29781.1 - 0.22 11.7 2.4 0.18 11.9 0.2 2.0 2 0 0 2 2 2 0 YrhC-like protein DUF21 PF01595.20 EPE29781.1 - 0.83 9.3 2.9 2.3 7.9 2.9 1.7 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain MFS_1 PF07690.16 EPE29782.1 - 7e-41 140.3 46.9 3.3e-40 138.1 46.9 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 EPE29783.1 - 2e-17 63.1 0.5 3.9e-17 62.2 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE29783.1 - 2e-09 37.4 9.4 3.4e-09 36.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rick_17kDa_Anti PF05433.15 EPE29784.1 - 0.027 14.3 0.4 0.064 13.1 0.4 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain Glyco_tranf_2_4 PF13704.6 EPE29785.1 - 5.2e-05 23.7 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 EPE29785.1 - 0.0015 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 92 bZIP_1 PF00170.21 EPE29786.1 - 1.3e-09 38.0 10.0 5e-09 36.1 10.0 2.1 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPE29786.1 - 0.002 18.2 10.7 0.002 18.2 10.7 2.5 2 0 0 2 2 2 1 Basic region leucine zipper Amidase PF01425.21 EPE29787.1 - 4.1e-97 326.0 0.0 5.3e-97 325.6 0.0 1.1 1 0 0 1 1 1 1 Amidase HET PF06985.11 EPE29788.1 - 2.5e-24 86.3 3.0 1.7e-23 83.6 3.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sporozoite_P67 PF05642.11 EPE29789.1 - 0.0002 19.6 2.4 0.0002 19.6 2.4 1.4 2 0 0 2 2 2 1 Sporozoite P67 surface antigen BUD22 PF09073.10 EPE29789.1 - 0.00049 19.6 16.4 0.00076 18.9 16.4 1.2 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 EPE29789.1 - 0.0046 15.3 13.5 0.0046 15.3 13.5 2.0 2 0 0 2 2 2 1 CDC45-like protein PRP38_assoc PF12871.7 EPE29789.1 - 0.018 15.7 16.5 0.018 15.7 16.5 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term FAM176 PF14851.6 EPE29789.1 - 0.048 13.3 9.7 0.053 13.2 2.8 2.4 2 0 0 2 2 2 0 FAM176 family DUF4611 PF15387.6 EPE29789.1 - 0.22 11.8 17.7 0.15 12.3 6.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Na_trans_assoc PF06512.13 EPE29789.1 - 0.22 11.8 11.0 0.44 10.8 10.4 1.6 1 1 0 1 1 1 0 Sodium ion transport-associated AT_hook PF02178.19 EPE29789.1 - 0.41 10.7 8.0 1.7 8.8 8.0 2.2 1 0 0 1 1 1 0 AT hook motif CPSF100_C PF13299.6 EPE29789.1 - 1.2 9.3 9.1 1.5 9.0 2.0 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 EPE29789.1 - 2.3 7.1 8.5 4.9 6.0 2.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) NOA36 PF06524.12 EPE29789.1 - 3.1 7.0 15.4 0.27 10.5 9.1 2.0 2 0 0 2 2 2 0 NOA36 protein Striatin PF08232.12 EPE29789.1 - 3.4 8.2 14.4 1.4 9.5 6.4 2.3 2 0 0 2 2 2 0 Striatin family Vezatin PF12632.7 EPE29789.1 - 3.4 7.0 4.0 5.9 6.2 4.0 1.3 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Connexin PF00029.19 EPE29789.1 - 4 7.1 9.6 2 8.1 2.2 2.2 2 0 0 2 2 2 0 Connexin PTPRCAP PF15713.5 EPE29789.1 - 4.7 7.5 21.5 0.85 9.9 11.3 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Peptidase_S49_N PF08496.10 EPE29789.1 - 6.1 6.9 5.6 14 5.8 0.6 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Zn_clus PF00172.18 EPE29791.1 - 4.9e-07 29.8 11.6 7.7e-07 29.1 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 EPE29792.1 - 1.8e-47 161.5 0.2 3.4e-47 160.6 0.2 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 EPE29792.1 - 5.6e-05 23.2 0.0 0.00023 21.3 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-NOSIP PF15906.5 EPE29792.1 - 0.0052 16.9 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein DUF4570 PF15134.6 EPE29794.1 - 0.015 15.3 0.6 0.028 14.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Trnau1ap PF17654.1 EPE29794.1 - 0.061 14.2 0.2 0.099 13.5 0.2 1.4 1 0 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins FGGY_C PF02782.16 EPE29795.1 - 1.4e-73 246.9 0.7 2.1e-73 246.3 0.7 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EPE29795.1 - 3.6e-66 223.2 0.0 5.1e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Thiolase_N PF00108.23 EPE29796.1 - 3.4e-73 246.2 0.9 4.9e-73 245.7 0.9 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EPE29796.1 - 2.3e-44 150.0 0.3 5.5e-44 148.7 0.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EPE29796.1 - 0.052 13.1 1.5 0.21 11.1 0.6 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Ran_BP1 PF00638.18 EPE29798.1 - 2.2e-50 170.0 1.8 3.4e-50 169.4 1.8 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 EPE29798.1 - 3.6e-06 26.9 0.6 2e-05 24.5 0.6 1.9 1 1 0 1 1 1 1 WH1 domain CK2S PF15011.6 EPE29798.1 - 0.015 15.2 0.7 0.024 14.5 0.7 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate PS-DH PF14765.6 EPE29798.1 - 0.034 13.4 0.1 0.069 12.4 0.1 1.5 1 0 0 1 1 1 0 Polyketide synthase dehydratase VID27_PH PF17747.1 EPE29798.1 - 0.044 14.1 0.1 0.062 13.6 0.1 1.2 1 0 0 1 1 1 0 VID27 PH-like domain CDC27 PF09507.10 EPE29798.1 - 0.62 9.4 16.6 0.75 9.1 16.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 YEATS PF03366.16 EPE29799.1 - 4.7e-18 64.9 0.0 1.1e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 YEATS family BET PF17035.5 EPE29799.1 - 1.4e-08 34.8 0.6 2.8e-08 33.8 0.6 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF3083 PF11281.8 EPE29799.1 - 0.013 14.8 0.1 0.057 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3083) PPP1R26_N PF15740.5 EPE29799.1 - 0.071 11.8 0.1 0.088 11.5 0.1 1.0 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 26 N-terminus SLX9 PF15341.6 EPE29799.1 - 0.11 12.9 4.1 0.18 12.2 3.4 1.6 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 DUF4604 PF15377.6 EPE29800.1 - 1.8e-27 96.9 19.5 2e-27 96.7 19.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) UPF0182 PF03699.13 EPE29800.1 - 0.27 9.3 0.5 0.32 9.0 0.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Presenilin PF01080.17 EPE29800.1 - 5.5 5.7 8.8 6.6 5.4 8.8 1.2 1 0 0 1 1 1 0 Presenilin Glyco_transf_15 PF01793.16 EPE29801.1 - 5.2e-96 321.7 10.0 5.6e-95 318.3 10.0 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF4048 PF13257.6 EPE29801.1 - 0.046 13.5 0.1 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4048) MFS_1 PF07690.16 EPE29802.1 - 5e-28 98.0 45.1 4.6e-20 71.8 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.27 EPE29804.1 - 5.4e-43 144.9 8.0 4.1e-16 58.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Vps55 PF04133.14 EPE29811.1 - 2.6e-47 159.6 5.4 3e-47 159.4 5.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Proteasome PF00227.26 EPE29812.1 - 5.3e-49 166.3 0.1 6.8e-49 165.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EPE29812.1 - 7.5e-11 41.5 0.2 1.2e-10 40.9 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lysine_decarbox PF03641.14 EPE29813.1 - 8.3e-30 103.6 0.0 1.2e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EPE29813.1 - 0.00079 19.0 1.5 0.0043 16.6 1.5 2.0 1 1 0 1 1 1 1 SLOG cluster4 family LSDAT_prok PF18171.1 EPE29813.1 - 0.093 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote CLPTM1 PF05602.12 EPE29814.1 - 6.4e-162 539.4 0.3 7.7e-162 539.2 0.3 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF4293 PF14126.6 EPE29814.1 - 0.047 13.9 1.9 0.13 12.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Longin PF13774.6 EPE29815.1 - 1.9e-26 91.9 1.0 2.5e-26 91.5 0.4 1.5 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EPE29815.1 - 1.3e-15 56.9 0.0 1.4e-14 53.6 0.0 2.2 2 0 0 2 2 2 1 Synaptobrevin DUF5435 PF17503.2 EPE29815.1 - 0.012 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5435) EMP24_GP25L PF01105.24 EPE29815.1 - 0.043 13.8 3.4 1.5 8.7 0.6 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4763 PF15960.5 EPE29815.1 - 0.072 12.4 0.2 0.72 9.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) CDH-cyt PF16010.5 EPE29817.1 - 1.2e-53 181.5 0.7 1.9e-53 180.8 0.7 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 EPE29817.1 - 6.2e-25 88.2 0.1 1.2e-24 87.2 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE29817.1 - 3.4e-20 73.0 0.0 1.8e-19 70.7 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EPE29817.1 - 4e-06 26.2 1.0 0.0054 15.9 0.5 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EPE29817.1 - 0.00011 22.3 0.1 0.00055 20.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE29817.1 - 0.00022 20.6 0.0 0.00063 19.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE29817.1 - 0.0029 16.9 0.2 0.011 15.0 0.5 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE29817.1 - 0.0048 15.6 0.2 0.0071 15.1 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EPE29817.1 - 0.067 12.4 0.6 0.13 11.5 0.6 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 EPE29817.1 - 0.071 12.4 0.1 0.17 11.2 0.1 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EPE29817.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 EPE29817.1 - 0.18 11.0 0.2 0.29 10.3 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EPE29817.1 - 0.24 10.5 0.1 0.37 9.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HET PF06985.11 EPE29819.1 - 2.1e-37 128.7 0.2 4.6e-37 127.6 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WW PF00397.26 EPE29819.1 - 0.0034 17.4 1.6 0.021 14.9 0.2 2.6 2 0 0 2 2 2 1 WW domain DUF3983 PF13137.6 EPE29820.1 - 0.15 11.9 1.7 0.31 10.9 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) Chorismate_bind PF00425.18 EPE29821.1 - 1.4e-69 234.5 0.0 6.5e-67 225.8 0.0 2.2 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EPE29821.1 - 5.6e-24 85.0 0.0 4.8e-22 78.6 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EPE29821.1 - 6.6e-14 52.3 0.0 1.9e-13 50.9 0.0 1.8 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EPE29821.1 - 0.00018 21.3 0.3 0.0041 16.9 0.0 2.3 2 0 0 2 2 2 1 Peptidase C26 Mso1_Sec1_bdg PF14475.6 EPE29822.1 - 3.8e-12 45.6 0.0 6.3e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.17 EPE29823.1 - 6.2e-40 136.5 1.4 1.3e-39 135.5 1.4 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 EPE29823.1 - 1.9e-30 105.4 10.4 1.9e-30 105.4 10.4 2.5 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EPE29823.1 - 3e-05 23.5 13.9 3.9e-05 23.2 13.9 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 EPE29823.1 - 0.049 13.4 0.6 0.093 12.5 0.6 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain SMN PF06003.12 EPE29823.1 - 0.091 12.0 2.7 0.17 11.1 2.7 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) TFIIF_alpha PF05793.12 EPE29823.1 - 1.6 7.2 23.1 1.9 6.9 23.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Drc1-Sld2 PF11719.8 EPE29823.1 - 2.9 7.3 12.3 4.9 6.6 12.3 1.4 1 1 0 1 1 1 0 DNA replication and checkpoint protein DUF1996 PF09362.10 EPE29824.1 - 8.3e-77 258.3 2.6 1.1e-76 257.9 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Ank_4 PF13637.6 EPE29825.1 - 0.00015 22.2 0.1 0.35 11.5 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE29825.1 - 0.00023 21.7 0.0 0.089 13.4 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Peptidase_S8 PF00082.22 EPE29825.1 - 0.0008 18.8 1.5 0.5 9.6 0.1 2.7 1 1 1 2 2 2 2 Subtilase family Ank PF00023.30 EPE29825.1 - 0.0011 19.4 0.0 1 9.9 0.0 3.9 3 1 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EPE29825.1 - 0.019 15.5 0.0 15 6.5 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 EPE29826.1 - 1e-95 314.4 30.5 7e-11 42.6 0.0 14.2 3 3 8 13 13 13 12 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE29826.1 - 2e-69 229.1 29.0 6.5e-09 36.2 0.0 15.4 11 2 5 16 16 16 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE29826.1 - 3.2e-67 214.5 21.0 7.5e-05 22.8 0.0 23.4 25 0 0 25 25 25 13 Ankyrin repeat Ank_5 PF13857.6 EPE29826.1 - 3.7e-66 218.3 30.3 6.4e-11 42.3 0.5 15.9 11 4 5 17 17 17 13 Ankyrin repeats (many copies) Ank PF00023.30 EPE29826.1 - 7.9e-66 215.8 36.9 7.3e-06 26.2 0.1 21.7 21 1 1 22 22 22 16 Ankyrin repeat SPRY PF00622.28 EPE29826.1 - 3.4e-14 53.0 0.1 7.9e-14 51.8 0.1 1.7 1 0 0 1 1 1 1 SPRY domain DUF4448 PF14610.6 EPE29828.1 - 0.047 13.5 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) MHYT PF03707.16 EPE29828.1 - 4.2 7.6 5.3 0.74 10.0 0.4 2.1 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat Elong_Iki1 PF10483.9 EPE29829.1 - 8.6e-80 268.4 0.0 1.2e-79 268.0 0.0 1.2 1 0 0 1 1 1 1 Elongator subunit Iki1 Glyco_hydro_63 PF03200.16 EPE29830.1 - 1.2e-170 568.5 2.2 1.6e-169 564.8 2.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EPE29830.1 - 1.8e-84 283.4 0.2 4.5e-82 275.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EPE29830.1 - 0.0042 16.0 0.2 0.0075 15.1 0.2 1.3 1 0 0 1 1 1 1 Trehalase SNRNP27 PF08648.12 EPE29831.1 - 2.3e-27 94.8 2.2 5.1e-27 93.7 2.2 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Helo_like_N PF17111.5 EPE29832.1 - 3.2e-05 23.4 0.6 3.2e-05 23.4 0.6 1.6 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Ank_2 PF12796.7 EPE29832.1 - 0.0067 17.0 0.1 0.075 13.6 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) RmuC PF02646.16 EPE29832.1 - 0.039 13.1 0.4 0.067 12.3 0.4 1.3 1 0 0 1 1 1 0 RmuC family Cas_GSU0053 PF09617.10 EPE29832.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Ank_3 PF13606.6 EPE29832.1 - 0.2 12.3 0.2 2 9.2 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat p450 PF00067.22 EPE29833.1 - 9.6e-49 166.4 0.0 1.2e-48 166.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FTA2 PF13095.6 EPE29835.1 - 6.3e-61 205.7 0.0 9.3e-61 205.2 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 MnmE_helical PF12631.7 EPE29836.1 - 1.2e-36 126.9 4.3 1.7e-36 126.3 4.3 1.3 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EPE29836.1 - 7.5e-34 116.5 0.0 2e-33 115.1 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EPE29836.1 - 2.3e-19 69.6 0.0 6e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EPE29836.1 - 5.6e-08 33.0 0.3 1.9e-07 31.3 0.1 2.2 2 1 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 EPE29836.1 - 1.2e-05 24.9 0.0 2.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EPE29836.1 - 0.0088 16.0 0.1 0.97 9.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Arf PF00025.21 EPE29836.1 - 0.044 13.2 0.0 2 7.9 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family G-alpha PF00503.20 EPE29836.1 - 0.045 12.9 0.1 0.15 11.2 0.1 1.6 1 1 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.27 EPE29836.1 - 0.072 13.6 0.0 0.25 11.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter PTS_IIB PF02302.17 EPE29836.1 - 0.2 12.4 1.1 1.2 9.9 0.1 2.3 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit DUF4404 PF14357.6 EPE29836.1 - 9.6 6.9 8.5 0.7 10.6 1.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) HATPase_c PF02518.26 EPE29838.1 - 1.9e-16 60.5 0.1 6.1e-16 58.9 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPE29838.1 - 6.4e-13 48.9 0.2 1.5e-12 47.7 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPE29838.1 - 1.5e-11 44.1 0.1 4.7e-11 42.6 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 EPE29838.1 - 0.0026 18.1 0.0 0.0059 16.9 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EPE29838.1 - 0.17 12.5 0.0 0.6 10.7 0.0 2.0 2 0 0 2 2 2 0 GAF domain RabGAP-TBC PF00566.18 EPE29839.1 - 5.6e-36 124.2 1.7 1.2e-35 123.1 1.7 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 EPE29839.1 - 7.6e-07 28.8 0.0 6.2e-05 22.5 0.0 3.0 2 1 0 2 2 2 1 Rab-binding domain (RBD) LysR_substrate PF03466.20 EPE29839.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain Cytomega_UL20A PF05984.12 EPE29841.1 - 0.19 12.1 2.9 0.29 11.5 2.9 1.5 1 1 0 1 1 1 0 Cytomegalovirus UL20A protein NOA36 PF06524.12 EPE29841.1 - 1.2 8.4 4.3 1.4 8.2 4.3 1.0 1 0 0 1 1 1 0 NOA36 protein Asp PF00026.23 EPE29842.1 - 7.6e-20 71.6 0.1 1.2e-19 70.9 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPE29842.1 - 0.011 16.0 0.3 0.069 13.4 0.0 2.6 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal Helo_like_N PF17111.5 EPE29842.1 - 0.11 11.9 0.5 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins FAM75 PF14650.6 EPE29844.1 - 4.6 6.7 15.8 91 2.4 17.6 1.9 2 0 0 2 2 2 0 FAM75 family MRJP PF03022.16 EPE29845.1 - 7.9e-25 87.8 0.0 1.2e-24 87.2 0.0 1.3 1 1 0 1 1 1 1 Major royal jelly protein NHL PF01436.21 EPE29845.1 - 0.065 13.3 0.0 4 7.6 0.0 2.7 2 0 0 2 2 2 0 NHL repeat GFA PF04828.14 EPE29846.1 - 0.00047 20.4 3.3 0.00047 20.4 3.3 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.14 EPE29846.1 - 0.042 14.1 3.8 0.058 13.6 3.8 1.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MMtag PF10159.9 EPE29847.1 - 3.7e-32 110.4 4.3 3.7e-32 110.4 4.3 2.2 2 0 0 2 2 2 1 Multiple myeloma tumor-associated Ribonuc_L-PSP PF01042.21 EPE29848.1 - 2.1e-18 66.5 0.0 2.6e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peroxidase_2 PF01328.17 EPE29850.1 - 8.6e-47 160.1 0.0 1.5e-46 159.3 0.0 1.4 1 0 0 1 1 1 1 Peroxidase, family 2 HET PF06985.11 EPE29850.1 - 3.1e-24 86.0 0.1 5.8e-24 85.1 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3684 PF12449.8 EPE29851.1 - 0 1476.5 0.0 0 1476.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 EPE29851.1 - 0.001 18.9 0.0 0.0059 16.4 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2156 PF09924.9 EPE29851.1 - 0.072 12.1 2.5 1.2 8.1 0.4 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2156) RadC PF04002.15 EPE29852.1 - 0.021 14.8 0.0 0.078 12.9 0.0 1.9 1 1 1 2 2 2 0 RadC-like JAB domain Mei5_like PF17021.5 EPE29852.1 - 0.89 9.6 5.6 3.7 7.6 0.1 4.0 4 0 0 4 4 4 0 Putative double-strand recombination repair-like CorA PF01544.18 EPE29854.1 - 3.5e-09 36.4 2.2 3.5e-09 36.4 2.2 2.1 1 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Phage_holin_3_6 PF07332.11 EPE29854.1 - 0.17 12.0 0.7 0.28 11.2 0.7 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Nup54 PF13874.6 EPE29855.1 - 0.011 15.9 0.1 0.015 15.4 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Med6 PF04934.14 EPE29857.1 - 1.4e-38 131.6 0.1 2e-38 131.2 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component CCD PF07860.11 EPE29857.1 - 0.42 10.6 3.9 2.6 8.1 1.8 2.4 2 0 0 2 2 2 0 WisP family C-Terminal Region HA2 PF04408.23 EPE29858.1 - 2.8e-22 79.0 0.0 2.8e-22 79.0 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EPE29858.1 - 3.8e-12 46.4 0.0 9.1e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EPE29858.1 - 1.3e-11 44.8 0.0 1.3e-10 41.6 0.0 2.7 4 0 0 4 4 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPE29858.1 - 1.8e-07 31.1 0.2 3.7e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EPE29858.1 - 0.00082 19.7 0.1 0.0037 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EPE29858.1 - 0.0025 18.2 0.2 0.0053 17.1 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPE29858.1 - 0.006 16.3 0.2 0.016 14.9 0.2 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EPE29858.1 - 0.026 13.6 0.0 0.067 12.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 EPE29858.1 - 0.098 13.1 0.0 0.098 13.1 0.0 3.4 3 1 0 3 3 3 0 AAA domain DUF2075 PF09848.9 EPE29858.1 - 0.12 11.6 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 EPE29858.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 EPE29858.1 - 0.22 11.9 1.5 0.62 10.4 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain SAPS PF04499.15 EPE29858.1 - 0.32 9.7 7.6 0.58 8.9 7.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 EPE29858.1 - 6.9 5.3 8.7 13 4.4 8.7 1.4 1 0 0 1 1 1 0 Presenilin PAC3 PF10178.9 EPE29859.1 - 5.5e-06 26.4 0.0 7.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 DIOX_N PF14226.6 EPE29860.1 - 1.2e-23 84.1 0.0 2.4e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPE29860.1 - 9.2e-20 71.0 0.0 4.5e-19 68.8 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Transp_cyt_pur PF02133.15 EPE29861.1 - 2.4e-104 349.5 42.3 3e-104 349.3 42.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COesterase PF00135.28 EPE29862.1 - 2.3e-63 214.9 0.1 3e-63 214.5 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE29862.1 - 0.00012 22.0 1.4 0.0016 18.3 0.1 2.5 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPE29862.1 - 0.03 13.8 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S10 PF00450.22 EPE29863.1 - 2.2e-81 274.4 0.1 2.9e-81 274.0 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DivIC PF04977.15 EPE29864.1 - 0.00019 21.2 15.6 0.075 12.8 0.0 4.4 4 0 0 4 4 4 2 Septum formation initiator Cnn_1N PF07989.11 EPE29864.1 - 0.0011 19.0 23.4 0.041 14.0 1.0 4.3 3 2 1 4 4 4 2 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 EPE29864.1 - 0.017 15.2 18.1 0.027 14.6 3.0 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF3509 PF12021.8 EPE29864.1 - 0.019 14.7 0.2 0.064 13.0 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) DUF4795 PF16043.5 EPE29864.1 - 0.042 13.4 10.7 0.19 11.3 1.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) Rootletin PF15035.6 EPE29864.1 - 0.061 13.3 18.6 6.3 6.8 2.0 3.7 2 1 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion YabA PF06156.13 EPE29864.1 - 0.51 11.0 21.3 0.23 12.1 1.6 4.2 3 2 1 4 4 4 0 Initiation control protein YabA MPS2 PF17060.5 EPE29864.1 - 0.62 9.3 9.8 0.48 9.6 4.1 2.1 2 0 0 2 2 2 0 Monopolar spindle protein 2 T6PP_N PF18572.1 EPE29864.1 - 0.97 9.3 11.0 0.82 9.6 0.6 3.0 2 1 1 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain HALZ PF02183.18 EPE29864.1 - 1.4 9.2 19.3 1.9 8.7 2.4 5.0 5 0 0 5 5 5 0 Homeobox associated leucine zipper Atg14 PF10186.9 EPE29864.1 - 1.5 7.8 11.4 3.4 6.6 1.5 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 EPE29864.1 - 2.1 6.8 7.5 7.8 5.0 3.0 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A APG6_N PF17675.1 EPE29864.1 - 2.5 8.6 19.5 2.2 8.8 5.0 2.8 2 1 1 3 3 3 0 Apg6 coiled-coil region bZIP_1 PF00170.21 EPE29864.1 - 4 7.6 18.2 2.6 8.2 0.7 4.3 5 1 0 5 5 5 0 bZIP transcription factor Pkinase PF00069.25 EPE29866.1 - 8.9e-22 77.7 0.0 1.8e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE29866.1 - 1.8e-11 43.8 0.0 6.6e-11 42.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase zf-UBP PF02148.19 EPE29866.1 - 0.19 12.1 2.1 0.61 10.5 2.1 1.9 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_4 PF13894.6 EPE29866.1 - 0.37 11.7 2.0 0.78 10.7 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger BTRD1 PF17660.1 EPE29867.1 - 1.2e-95 313.2 38.0 5e-21 74.3 0.8 5.1 5 0 0 5 5 5 5 Bacterial tandem repeat domain 1 Ivy PF08816.11 EPE29867.1 - 0.51 10.5 4.0 1.2 9.4 0.7 2.5 2 2 0 2 2 2 0 Inhibitor of vertebrate lysozyme (Ivy) SMYLE_N PF18615.1 EPE29868.1 - 0.32 10.5 1.5 0.43 10.1 1.5 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain NPF PF16601.5 EPE29869.1 - 0.021 15.3 1.4 0.049 14.1 0.2 2.1 2 0 0 2 2 2 0 Rabosyn-5 repeating NPF sequence-motif DUF3099 PF11298.8 EPE29869.1 - 5.9 7.1 6.6 0.52 10.5 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) ArsB PF02040.15 EPE29870.1 - 6.1e-11 42.3 24.1 1.7e-06 27.7 11.6 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein RskA PF10099.9 EPE29870.1 - 0.86 9.9 7.7 3.6 7.8 0.5 2.6 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Wzy_C_2 PF11846.8 EPE29870.1 - 1.8 8.4 7.3 0.88 9.5 0.5 3.2 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal DUF1240 PF06836.12 EPE29870.1 - 8.9 6.9 9.5 1.3 9.6 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1240) FH2 PF02181.23 EPE29872.1 - 6.2e-82 275.7 6.9 6.2e-82 275.7 6.9 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EPE29872.1 - 2.1e-65 219.8 0.0 2.1e-65 219.8 0.0 3.0 3 1 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EPE29872.1 - 1.1e-53 181.8 1.4 6.2e-53 179.3 0.7 2.6 1 1 1 2 2 2 1 Diaphanous FH3 Domain STAC2_u1 PF16664.5 EPE29875.1 - 3.3 8.2 6.3 0.31 11.5 1.2 1.8 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Sugar_tr PF00083.24 EPE29876.1 - 2.2e-123 412.5 22.8 2.6e-123 412.3 22.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE29876.1 - 4.4e-18 65.3 46.1 5.5e-17 61.7 40.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2264 PF10022.9 EPE29877.1 - 2.6e-131 437.9 0.0 3.2e-131 437.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Aminotran_5 PF00266.19 EPE29878.1 - 6.1e-33 114.3 0.0 1.5e-21 76.8 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V adh_short PF00106.25 EPE29879.1 - 6.6e-16 58.3 0.0 1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE29879.1 - 2.7e-12 46.8 0.0 4e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AMP-binding PF00501.28 EPE29880.1 - 2.9e-39 134.9 0.0 3.8e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TRAPPC9-Trs120 PF08626.11 EPE29881.1 - 0 1485.3 0.0 0 1485.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 EPE29881.1 - 0.098 13.0 0.4 0.34 11.2 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ADH_zinc_N PF00107.26 EPE29883.1 - 4.9e-25 88.0 0.0 8.3e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE29883.1 - 1.1e-17 65.4 0.0 1.9e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE29883.1 - 0.00048 20.0 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 EPE29883.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EPE29883.1 - 0.059 13.1 0.1 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N_2 PF16884.5 EPE29883.1 - 0.065 13.1 0.1 0.43 10.5 0.1 2.1 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase HEAT_2 PF13646.6 EPE29884.1 - 6.2e-09 36.1 0.9 0.95 9.9 0.0 7.4 6 2 2 8 8 8 2 HEAT repeats HEAT PF02985.22 EPE29884.1 - 6.7e-06 25.9 4.9 4.3 7.9 0.0 8.8 10 0 0 10 10 10 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EPE29884.1 - 8.9e-06 26.2 0.0 0.14 12.7 0.0 4.3 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EPE29884.1 - 5.1e-05 22.9 0.8 3.1 7.3 0.0 4.4 4 0 0 4 4 4 3 CLASP N terminal Cnd3 PF12719.7 EPE29884.1 - 0.0037 16.5 2.4 0.97 8.6 0.0 4.2 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Transcrip_reg PF01709.20 EPE29885.1 - 4.6e-59 199.7 6.0 9e-58 195.5 6.0 2.0 1 1 0 1 1 1 1 Transcriptional regulator DUF1707 PF08044.11 EPE29885.1 - 1.3 9.2 3.2 42 4.3 0.0 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF1707) Pet100 PF09803.9 EPE29886.1 - 3.4e-09 37.1 0.1 3.8e-09 36.9 0.1 1.0 1 0 0 1 1 1 1 Pet100 ECH_1 PF00378.20 EPE29887.1 - 9.8e-26 90.6 0.0 1.3e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPE29887.1 - 4.1e-15 56.1 0.0 4.6e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase cwf21 PF08312.12 EPE29888.1 - 5.1e-16 58.6 9.6 5.1e-16 58.6 9.6 1.7 2 0 0 2 2 2 1 cwf21 domain DUF3078 PF11276.8 EPE29888.1 - 0.13 12.7 0.1 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3078) D123 PF07065.14 EPE29889.1 - 7.8e-120 399.7 0.5 9.3e-120 399.4 0.5 1.1 1 0 0 1 1 1 1 D123 adh_short_C2 PF13561.6 EPE29890.1 - 4.4e-60 203.1 0.1 7.2e-60 202.5 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE29890.1 - 3.8e-46 157.0 0.2 4.9e-46 156.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE29890.1 - 2.2e-10 40.8 0.7 4.1e-10 39.8 0.3 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EPE29890.1 - 0.016 14.6 0.1 0.027 13.9 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EPE29890.1 - 0.095 11.8 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein A_deaminase PF00962.22 EPE29891.1 - 6.9e-24 84.8 0.0 1.1e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 EPE29891.1 - 0.067 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal Acetyltransf_1 PF00583.25 EPE29892.1 - 3.2e-15 56.4 0.1 1.5e-07 31.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE29892.1 - 4.6e-15 55.8 0.0 1.9e-06 28.2 0.1 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPE29892.1 - 6.7e-10 39.1 0.1 0.00069 19.7 0.1 3.3 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPE29892.1 - 7.1e-09 35.7 0.1 0.0014 18.5 0.1 3.2 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE29892.1 - 2.8e-06 27.2 0.2 0.0044 17.0 0.2 2.8 2 1 0 2 2 2 2 FR47-like protein Acetyltransf_CG PF14542.6 EPE29892.1 - 3e-05 24.0 0.0 0.088 12.9 0.0 2.4 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 EPE29892.1 - 0.015 15.3 0.0 0.61 10.1 0.0 2.6 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_6 PF13480.7 EPE29892.1 - 0.094 12.9 0.0 0.72 10.0 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain F_actin_bund_C PF18060.1 EPE29893.1 - 3 8.0 11.7 5.5 7.2 11.7 1.4 1 0 0 1 1 1 0 F actin bundling C terminal Cellulase PF00150.18 EPE29894.1 - 2.9e-47 161.4 0.3 4e-47 161.0 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Hus1 PF04005.12 EPE29898.1 - 2.7e-91 305.7 0.0 3e-91 305.6 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Phosphodiest PF01663.22 EPE29900.1 - 4.3e-15 56.2 0.1 6.8e-15 55.5 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EPE29900.1 - 2.3e-05 23.9 0.1 4.3e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EPE29900.1 - 0.0015 17.9 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 Sulfatase UPF0220 PF05255.11 EPE29901.1 - 8.6e-70 233.6 5.5 9.7e-70 233.4 5.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF5337 PF17272.2 EPE29901.1 - 9.5 6.1 6.8 4.1 7.3 0.5 2.7 1 1 2 3 3 3 0 Family of unknown function (DUF5337) SMI1_KNR4 PF09346.10 EPE29902.1 - 1.4e-33 116.1 0.0 2.5e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Sec8_exocyst PF04048.14 EPE29903.1 - 1.9e-45 154.3 0.2 4.5e-45 153.0 0.2 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EPE29903.1 - 2.4e-07 30.3 0.9 4.2e-07 29.6 0.9 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex HIP1_clath_bdg PF16515.5 EPE29903.1 - 0.0055 17.3 0.3 0.016 15.8 0.3 1.8 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 adh_short PF00106.25 EPE29905.1 - 1.5e-13 50.6 0.0 2.2e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE29905.1 - 4.2e-07 29.8 0.0 6.1e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE29905.1 - 3.1e-05 24.0 0.0 4.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 KR domain STAS PF01740.21 EPE29905.1 - 0.022 14.4 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 STAS domain Polysacc_synt_2 PF02719.15 EPE29905.1 - 0.034 13.3 0.0 0.04 13.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pkinase PF00069.25 EPE29906.1 - 2.5e-50 171.3 0.0 3.9e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE29906.1 - 1.7e-30 106.2 0.0 2.6e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE29906.1 - 7.9e-10 38.5 0.0 1.2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EPE29906.1 - 0.0085 15.5 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Hydrolase PF00702.26 EPE29907.1 - 3.5e-05 24.2 0.0 4.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EPE29907.1 - 0.035 13.9 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Acid Phosphatase HAD_2 PF13419.6 EPE29907.1 - 0.094 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Fes1 PF08609.10 EPE29908.1 - 6.1e-29 100.8 1.9 2.4e-28 98.9 0.1 2.5 2 1 1 3 3 3 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 EPE29908.1 - 6.8e-05 23.2 0.1 0.00023 21.5 0.1 1.9 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 EPE29908.1 - 0.00042 20.3 0.2 0.0056 16.8 0.1 2.6 2 0 0 2 2 2 1 HEAT repeat Arm PF00514.23 EPE29908.1 - 0.0014 18.6 0.1 0.46 10.6 0.0 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EPE29908.1 - 0.022 15.3 0.8 0.73 10.4 0.1 3.1 2 1 2 4 4 4 0 HEAT-like repeat HrpB7 PF09486.10 EPE29908.1 - 0.049 14.0 0.1 0.075 13.4 0.1 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Cnd1 PF12717.7 EPE29908.1 - 0.078 13.0 0.5 3.2 7.8 0.0 2.5 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DJ-1_PfpI PF01965.24 EPE29909.1 - 2.3e-14 53.5 0.0 3.1e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Aa_trans PF01490.18 EPE29910.1 - 1.3e-60 205.3 26.9 1.6e-60 205.0 26.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EPE29910.1 - 2.5 7.1 24.6 0.013 14.6 11.2 2.2 2 0 0 2 2 2 0 Tryptophan/tyrosine permease family Bmt2 PF11968.8 EPE29911.1 - 3.8e-87 291.8 0.1 4.9e-87 291.4 0.1 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 EPE29911.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L23eN PF03939.13 EPE29912.1 - 9.4e-26 89.8 10.7 2.3e-25 88.6 10.7 1.7 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EPE29912.1 - 1.2e-15 57.6 3.2 1.3e-15 57.5 0.7 2.0 2 0 0 2 2 2 1 Ribosomal protein L23 CorA PF01544.18 EPE29913.1 - 7.6e-42 143.6 0.0 1e-41 143.2 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein YmdB PF13277.6 EPE29913.1 - 0.039 13.3 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 YmdB-like protein SPC12 PF06645.13 EPE29914.1 - 9.5e-29 99.3 0.1 1.1e-28 99.1 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2157 PF09925.9 EPE29914.1 - 0.0077 16.0 0.1 0.0088 15.8 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2157) DUF3040 PF11239.8 EPE29914.1 - 0.079 13.2 0.3 0.11 12.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) zf-rbx1 PF12678.7 EPE29915.1 - 2.3e-06 27.8 4.2 4e-06 27.0 4.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EPE29915.1 - 9.1e-06 25.6 1.8 1.4e-05 25.1 1.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PNRC PF15365.6 EPE29916.1 - 5.5e-08 32.4 8.9 5.5e-08 32.4 8.9 4.3 5 0 0 5 5 5 1 Proline-rich nuclear receptor coactivator motif GIDA PF01134.22 EPE29917.1 - 7.6e-158 525.7 0.0 9.3e-158 525.4 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EPE29917.1 - 2.7e-68 230.3 0.0 3.8e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 EPE29917.1 - 5.2e-06 26.1 0.9 7.7e-06 25.5 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE29917.1 - 3.9e-05 23.0 0.8 0.0001 21.7 0.8 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE29917.1 - 0.0047 16.1 3.1 0.0074 15.4 2.2 1.8 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EPE29917.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1184 PF06683.11 EPE29917.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) HI0933_like PF03486.14 EPE29917.1 - 0.15 10.7 2.6 0.44 9.2 0.7 2.1 2 0 0 2 2 2 0 HI0933-like protein U79_P34 PF03064.16 EPE29918.1 - 0.056 12.8 3.9 0.069 12.5 3.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Fungal_lectin PF07938.12 EPE29919.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal fucose-specific lectin Pyridoxal_deC PF00282.19 EPE29920.1 - 6.4e-78 262.1 0.0 9e-78 261.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EPE29920.1 - 1.3e-07 31.0 0.0 1.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 EPE29920.1 - 0.021 13.6 0.0 0.037 12.8 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain WD40 PF00400.32 EPE29921.1 - 5e-37 125.3 20.0 4.4e-07 30.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE29921.1 - 6.9e-15 55.1 0.1 0.00037 20.8 0.1 5.0 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPE29921.1 - 5.5e-05 22.3 0.2 0.87 8.5 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EPE29921.1 - 0.00012 22.0 0.0 0.11 12.4 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EPE29921.1 - 0.0017 17.8 0.0 0.066 12.5 0.0 2.8 2 1 1 4 4 4 1 WD40-like domain DivIC PF04977.15 EPE29921.1 - 0.81 9.5 3.5 1.4 8.7 3.5 1.4 1 0 0 1 1 1 0 Septum formation initiator WXG100 PF06013.12 EPE29921.1 - 1.8 8.9 4.5 2 8.7 1.8 2.4 3 0 0 3 3 3 0 Proteins of 100 residues with WXG A_deaminase PF00962.22 EPE29922.1 - 8.1e-24 84.5 0.0 1e-23 84.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Tyr-DNA_phospho PF06087.12 EPE29923.1 - 1.4e-87 294.4 0.0 1.9e-87 294.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EPE29923.1 - 3.3e-05 23.8 0.0 0.0027 17.6 0.0 2.7 3 0 0 3 3 3 1 PLD-like domain UIM PF02809.20 EPE29923.1 - 0.00085 19.1 1.0 0.00085 19.1 1.0 2.9 3 0 0 3 3 3 1 Ubiquitin interaction motif Gti1_Pac2 PF09729.9 EPE29924.1 - 1.4e-62 211.0 0.0 2.8e-62 210.0 0.0 1.5 1 0 0 1 1 1 1 Gti1/Pac2 family CDP-OH_P_transf PF01066.21 EPE29925.1 - 4.1e-14 53.1 0.4 4.1e-14 53.1 0.4 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase His_Phos_2 PF00328.22 EPE29927.1 - 6.2e-39 134.4 0.0 8.3e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HET PF06985.11 EPE29931.1 - 1.6e-12 48.0 3.6 1.1e-09 38.8 0.3 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Phage_CI_repr PF07022.13 EPE29932.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Sec16_C PF12931.7 EPE29933.1 - 2.8e-113 378.6 0.1 3.8e-113 378.1 0.1 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EPE29933.1 - 4.2e-35 120.9 0.0 1.5e-34 119.1 0.0 2.1 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.7 EPE29933.1 - 1.3e-13 51.7 12.7 1.3e-13 51.7 12.7 4.7 4 1 0 4 4 4 1 Vesicle coat trafficking protein Sec16 N-terminus Nup96 PF12110.8 EPE29933.1 - 0.13 11.4 0.0 0.33 10.0 0.0 1.7 1 0 0 1 1 1 0 Nuclear protein 96 PhoLip_ATPase_C PF16212.5 EPE29934.1 - 1.6e-51 175.4 4.6 1.6e-51 175.4 4.6 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EPE29934.1 - 5.4e-16 58.0 0.4 1.1e-15 57.1 0.4 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EPE29934.1 - 4.6e-13 49.9 0.3 3.1e-08 34.1 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPE29934.1 - 1.1e-05 25.5 0.0 0.00052 20.0 0.0 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EPE29934.1 - 0.0038 17.0 0.0 0.0097 15.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EPE29934.1 - 0.0057 16.2 0.0 0.0057 16.2 0.0 3.0 3 1 0 3 3 3 2 E1-E2 ATPase NAD_binding_1 PF00175.21 EPE29935.1 - 1.6e-09 38.4 0.0 1.9e-08 34.9 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EPE29935.1 - 4.3e-07 30.2 0.0 1.1e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EPE29935.1 - 0.01 15.9 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DUF3402 PF11882.8 EPE29937.1 - 4e-192 639.4 0.0 5.3e-192 639.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 EPE29937.1 - 1.6e-87 293.4 0.4 2.3e-87 292.9 0.4 1.2 1 0 0 1 1 1 1 N1221-like protein CHAT PF12770.7 EPE29939.1 - 1.9e-37 129.2 0.1 3.4e-37 128.4 0.1 1.3 1 0 0 1 1 1 1 CHAT domain ZZ PF00569.17 EPE29939.1 - 8.3e-11 41.5 6.0 1.7e-10 40.5 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 EPE29939.1 - 0.0012 19.1 8.0 0.0025 18.1 8.0 1.5 1 0 0 1 1 1 1 C1 domain Peptidase_C25 PF01364.18 EPE29939.1 - 0.01 15.1 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 Peptidase_C50 PF03568.17 EPE29939.1 - 0.073 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C50 BTB PF00651.31 EPE29940.1 - 2.6e-09 37.3 0.4 1e-07 32.1 0.4 2.4 1 1 0 1 1 1 1 BTB/POZ domain Aldo_ket_red PF00248.21 EPE29941.1 - 4e-68 229.7 0.0 4.6e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 EPE29942.1 - 3.2e-06 27.2 7.1 8.7e-06 25.8 7.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE29942.1 - 0.00022 20.2 1.5 0.0011 17.8 1.5 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain IMUP PF15761.5 EPE29942.1 - 0.67 10.7 4.4 1.3 9.7 4.4 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein EthD PF07110.11 EPE29943.1 - 5.2e-12 46.8 0.1 7.5e-12 46.2 0.1 1.3 1 1 0 1 1 1 1 EthD domain DUF5071 PF16804.5 EPE29943.1 - 0.086 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) ZZ PF00569.17 EPE29947.1 - 2.7 7.9 5.7 13 5.7 0.4 3.2 3 0 0 3 3 3 0 Zinc finger, ZZ type PGA2 PF07543.12 EPE29948.1 - 1.4e-23 83.4 7.7 9e-23 80.8 7.7 2.1 1 1 0 1 1 1 1 Protein trafficking PGA2 ApoB100_C PF12491.8 EPE29948.1 - 0.15 12.0 0.1 0.48 10.4 0.0 1.8 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal CENP-S PF15630.6 EPE29949.1 - 2.9e-33 114.1 0.0 3.5e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EPE29949.1 - 1e-06 28.8 0.0 1.3e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EPE29949.1 - 0.0069 16.4 0.0 0.014 15.4 0.0 1.5 2 0 0 2 2 2 1 Bromodomain associated TFIID-18kDa PF02269.16 EPE29949.1 - 0.2 11.7 0.0 0.29 11.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit MARVEL PF01284.23 EPE29950.1 - 1.1 9.2 21.5 6.7 6.7 22.0 1.8 1 1 0 1 1 1 0 Membrane-associating domain ADH_N PF08240.12 EPE29951.1 - 9.2e-25 86.7 5.7 1.6e-24 85.8 5.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE29951.1 - 6.2e-15 55.3 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EPE29951.1 - 0.00097 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EPE29951.1 - 0.0034 16.7 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DZR PF12773.7 EPE29951.1 - 0.0073 16.3 1.4 0.018 15.0 1.4 1.7 1 1 0 1 1 1 1 Double zinc ribbon Fungal_trans PF04082.18 EPE29952.1 - 2.8e-31 108.5 0.1 5.3e-31 107.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE29952.1 - 9.3e-07 28.9 8.1 1.8e-06 28.0 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_C PF00043.25 EPE29953.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Amidase PF01425.21 EPE29954.1 - 7.3e-31 107.6 3.4 1.1e-30 107.0 2.3 1.7 2 0 0 2 2 2 1 Amidase BpuJI_N PF11564.8 EPE29954.1 - 0.079 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal zf-RING_2 PF13639.6 EPE29955.1 - 9.4e-09 35.5 9.1 1.5e-08 34.8 9.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EPE29955.1 - 1.5e-08 34.3 5.8 2.3e-08 33.8 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE29955.1 - 3.4e-08 33.2 5.5 8.5e-07 28.7 5.7 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EPE29955.1 - 5.4e-08 32.5 10.4 9.7e-08 31.7 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE29955.1 - 1.8e-07 31.1 6.8 3.7e-07 30.0 6.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EPE29955.1 - 8.7e-07 28.7 9.3 1.4e-06 28.1 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE29955.1 - 9.3e-07 28.7 7.8 1.4e-06 28.2 7.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EPE29955.1 - 1.3e-06 28.4 2.5 2.9e-06 27.2 2.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EPE29955.1 - 2e-06 27.9 9.5 3.3e-06 27.1 9.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EPE29955.1 - 1.3e-05 25.4 5.2 2.6e-05 24.4 5.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zinc_ribbon_9 PF14369.6 EPE29955.1 - 0.04 14.2 0.7 0.04 14.2 0.7 1.9 2 0 0 2 2 2 0 zinc-ribbon zf-RING_6 PF14835.6 EPE29955.1 - 0.044 13.7 6.6 1.4 8.9 4.3 3.2 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 EPE29955.1 - 0.071 12.9 6.0 0.14 12.0 6.0 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-MIZ PF02891.20 EPE29955.1 - 0.11 12.2 8.5 0.2 11.5 8.5 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_4 PF14570.6 EPE29955.1 - 0.12 12.2 8.3 0.3 10.9 8.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 EPE29955.1 - 0.15 12.1 5.1 1 9.4 5.1 2.0 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 EPE29955.1 - 0.22 11.2 4.8 0.37 10.4 4.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1272 PF06906.11 EPE29955.1 - 0.27 11.4 4.8 0.59 10.3 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-piccolo PF05715.13 EPE29955.1 - 0.6 10.3 5.2 15 5.8 2.6 2.3 2 0 0 2 2 2 0 Piccolo Zn-finger zinc_ribbon_2 PF13240.6 EPE29955.1 - 1 9.2 4.5 17 5.2 0.0 2.8 2 1 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 EPE29955.1 - 2.8 8.0 6.4 4.5 7.3 6.4 1.3 1 0 0 1 1 1 0 zinc-ribbons Pellino PF04710.14 EPE29955.1 - 3.6 6.1 5.7 23 3.5 0.5 2.8 2 1 1 3 3 3 0 Pellino zf-C3H2C3 PF17122.5 EPE29955.1 - 8.7 6.5 9.1 41 4.3 9.1 2.0 1 1 0 1 1 1 0 Zinc-finger BRX_N PF13713.6 EPE29956.1 - 0.54 10.1 1.9 2.2 8.1 0.5 2.2 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain Gly-zipper_Omp PF13488.6 EPE29958.1 - 0.0003 20.7 0.3 0.00052 19.9 0.3 1.3 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 EPE29958.1 - 0.00078 19.1 0.8 0.0012 18.5 0.8 1.2 1 0 0 1 1 1 1 YMGG-like Gly-zipper Pkinase PF00069.25 EPE29959.1 - 1.9e-25 89.7 0.0 2.5e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE29959.1 - 2.7e-21 76.0 0.0 3.8e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EPE29959.1 - 0.074 12.7 0.1 4.7 6.8 0.0 2.8 1 1 2 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DUF1968 PF09291.10 EPE29959.1 - 0.092 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1968) Kinase-like PF14531.6 EPE29959.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 EPE29959.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAP2 PF01569.21 EPE29960.1 - 3.2e-10 39.9 4.6 3.2e-10 39.9 4.6 2.0 2 1 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EPE29960.1 - 0.0036 17.4 0.0 0.22 11.7 0.0 2.3 2 0 0 2 2 2 1 Divergent PAP2 family DUF2759 PF10958.8 EPE29960.1 - 0.034 13.9 1.8 0.062 13.0 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) UbiA PF01040.18 EPE29960.1 - 0.14 11.4 7.5 0.024 13.9 3.5 1.7 2 0 0 2 2 2 0 UbiA prenyltransferase family IBR PF01485.21 EPE29961.1 - 3.3e-21 75.3 33.7 1.9e-15 56.8 3.1 4.2 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 EPE29961.1 - 3.1e-17 62.9 0.0 6.6e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 EPE29961.1 - 0.00055 20.2 5.5 0.00055 20.2 5.5 4.6 3 1 1 4 4 4 2 Ring finger domain zf-RING_UBOX PF13445.6 EPE29961.1 - 0.0022 18.0 5.5 0.0022 18.0 5.5 3.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EPE29961.1 - 0.003 17.4 5.1 0.003 17.4 5.1 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE29961.1 - 0.018 15.0 4.7 0.018 15.0 4.7 3.9 3 1 0 3 3 3 0 zinc-RING finger domain zf-RING_11 PF17123.5 EPE29961.1 - 4.8 7.0 13.8 0.16 11.8 7.2 2.1 2 0 0 2 2 2 0 RING-like zinc finger AA_permease_2 PF13520.6 EPE29962.1 - 1.6e-60 205.1 45.3 2.2e-60 204.7 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE29962.1 - 3.6e-25 88.5 29.8 3.6e-25 88.5 29.8 2.1 2 0 0 2 2 2 1 Amino acid permease tRNA-synt_1 PF00133.22 EPE29963.1 - 1.2e-47 162.5 0.1 1.2e-16 60.2 0.2 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EPE29963.1 - 1.2e-40 139.0 0.0 2.2e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EPE29963.1 - 2.1e-27 95.9 0.1 2.9e-19 69.1 0.0 4.3 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EPE29963.1 - 8.9e-11 42.0 0.0 1.6e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EPE29963.1 - 0.0023 17.3 0.0 0.23 10.8 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain zf-ribbon_3 PF13248.6 EPE29963.1 - 0.025 14.0 3.3 1 8.9 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain tRNA-synt_1d PF00750.19 EPE29963.1 - 0.044 12.7 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) Zn-ribbon_8 PF09723.10 EPE29963.1 - 0.29 11.3 1.2 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Peptidase_S8 PF00082.22 EPE29964.1 - 1e-40 139.9 0.0 1.1e-39 136.5 0.0 2.5 2 1 0 2 2 2 1 Subtilase family fn3_5 PF06280.12 EPE29964.1 - 3.9e-07 30.8 0.5 7.3e-07 29.9 0.5 1.5 1 0 0 1 1 1 1 Fn3-like domain PilX PF13681.6 EPE29964.1 - 0.045 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Type IV pilus assembly protein PilX C-term MFS_1 PF07690.16 EPE29965.1 - 2.5e-39 135.2 59.6 2.7e-36 125.2 49.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE29965.1 - 0.0087 15.0 3.8 0.0087 15.0 3.8 3.6 2 1 1 3 3 3 3 Sugar (and other) transporter TPR_MLP1_2 PF07926.12 EPE29967.1 - 0.00054 20.0 22.8 0.00054 20.0 22.8 4.1 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EPE29967.1 - 0.003 16.5 20.1 0.003 16.5 20.1 3.3 1 1 2 3 3 3 1 Spc7 kinetochore protein TSC22 PF01166.18 EPE29967.1 - 0.061 13.7 1.1 0.061 13.7 1.1 5.3 4 3 3 7 7 7 0 TSC-22/dip/bun family SpoU_methylase PF00588.19 EPE29967.1 - 0.12 12.5 0.2 0.34 11.1 0.2 1.7 1 0 0 1 1 1 0 SpoU rRNA Methylase family ATP_bind_2 PF03668.15 EPE29967.1 - 0.43 9.8 4.4 0.2 10.9 1.7 1.8 1 1 0 1 1 1 0 P-loop ATPase protein family DUF2011 PF09428.10 EPE29968.1 - 1.3e-26 92.6 0.9 4.6e-26 90.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) CT_A_B PF02626.15 EPE29968.1 - 0.11 12.2 0.2 0.16 11.5 0.2 1.3 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain A and B Peptidase_S49_N PF08496.10 EPE29968.1 - 9 6.3 9.8 14 5.7 9.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NDT80_PhoG PF05224.12 EPE29969.1 - 2.4e-29 102.9 0.0 4.1e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF4555 PF15093.6 EPE29970.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4555) MTS PF05175.14 EPE29971.1 - 1.9e-07 30.8 0.0 2.3e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EPE29971.1 - 3.2e-07 30.3 0.0 1.8e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 EPE29971.1 - 7.8e-05 22.1 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_25 PF13649.6 EPE29971.1 - 0.00086 20.0 0.0 0.0028 18.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 EPE29971.1 - 0.00086 19.8 0.4 0.0044 17.6 0.4 2.2 1 1 0 1 1 1 1 PrmC N-terminal domain PrmA PF06325.13 EPE29971.1 - 0.14 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EPE29971.1 - 0.19 11.0 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 EPE29971.1 - 0.19 11.4 0.1 2.7 7.6 0.1 2.3 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 AviRa PF11599.8 EPE29971.1 - 0.2 11.1 0.1 1.5 8.2 0.1 2.0 1 1 1 2 2 2 0 RRNA methyltransferase AviRa Suc_Fer-like PF06999.12 EPE29972.1 - 1.8e-57 194.4 0.0 2.1e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Grg1 PF11034.8 EPE29974.1 - 4.5e-33 113.3 11.9 5e-33 113.1 11.9 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 CtnDOT_TraJ PF07863.11 EPE29974.1 - 0.22 12.2 2.0 0.28 11.9 2.0 1.1 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon EBP PF05241.12 EPE29975.1 - 6.8e-64 214.6 11.4 8e-64 214.4 11.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein TMEM208_SND2 PF05620.11 EPE29975.1 - 0.0062 16.3 7.3 0.04 13.7 0.1 2.4 2 0 0 2 2 2 2 SRP-independent targeting protein 2/TMEM208 zf-RING_UBOX PF13445.6 EPE29976.1 - 2.4e-06 27.5 10.6 5.6e-06 26.3 10.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EPE29976.1 - 3.2e-05 24.2 17.4 6.5e-05 23.2 17.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EPE29976.1 - 3.7e-05 23.6 17.8 7.3e-05 22.6 17.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 EPE29976.1 - 0.0028 17.4 13.6 0.0064 16.3 13.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 EPE29976.1 - 0.0053 16.7 6.5 0.011 15.7 6.5 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.25 EPE29976.1 - 0.0092 15.8 17.4 0.022 14.6 17.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Hexapep_loop PF18776.1 EPE29976.1 - 0.055 13.1 0.7 0.12 12.0 0.7 1.6 1 0 0 1 1 1 0 Hexapeptide repeat including loop Prok-RING_4 PF14447.6 EPE29976.1 - 0.16 11.8 18.5 0.11 12.4 10.6 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EPE29976.1 - 1.6 8.6 18.4 4.8 7.1 18.4 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_SprT PF17283.2 EPE29976.1 - 5.1 7.1 12.6 0.29 11.1 6.4 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain YdjO PF14169.6 EPE29977.1 - 0.086 12.6 0.2 0.19 11.5 0.2 1.5 1 0 0 1 1 1 0 Cold-inducible protein YdjO zf-C3HC4_3 PF13920.6 EPE29977.1 - 0.099 12.5 2.5 0.16 11.8 2.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE29978.1 - 1.1e-05 25.4 5.5 2.4e-05 24.3 5.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EPE29978.1 - 0.00016 21.9 9.5 0.00037 20.8 9.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EPE29978.1 - 0.0014 18.6 4.6 0.0014 18.6 4.6 2.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EPE29978.1 - 0.0038 17.1 3.5 0.0039 17.0 2.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPE29978.1 - 0.015 15.2 6.6 0.037 13.9 6.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE29978.1 - 0.023 14.5 6.8 0.072 12.9 6.8 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EPE29978.1 - 0.06 13.1 6.0 0.26 11.1 6.2 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 EPE29979.1 - 7.7e-07 29.0 3.8 1.1e-06 28.5 2.4 2.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EPE29979.1 - 3.1e-06 26.9 4.7 7e-06 25.8 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE29979.1 - 1.1e-05 25.7 5.8 2.5e-05 24.5 5.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EPE29979.1 - 6.2e-05 22.8 7.6 0.00013 21.8 7.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 EPE29979.1 - 0.00049 20.1 1.7 0.0011 19.0 1.7 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 EPE29979.1 - 0.00063 19.6 8.0 0.12 12.3 9.0 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EPE29979.1 - 0.00068 19.6 5.7 0.0013 18.6 5.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EPE29979.1 - 0.0012 18.7 6.4 0.0035 17.1 6.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EPE29979.1 - 0.0034 17.1 7.7 0.0034 17.1 7.7 2.3 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain FYVE PF01363.21 EPE29979.1 - 0.15 12.3 2.1 0.41 10.8 2.1 1.7 1 0 0 1 1 1 0 FYVE zinc finger zf-ANAPC11 PF12861.7 EPE29979.1 - 0.64 10.1 4.0 0.34 11.0 0.9 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn-C2H2_12 PF18112.1 EPE29979.1 - 1.4 9.5 4.4 21 5.7 0.2 3.0 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C3HC4_4 PF15227.6 EPE29979.1 - 1.9 8.7 9.0 4.6 7.5 9.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING LPD37 PF18853.1 EPE29981.1 - 0.1 12.1 0.0 0.33 10.5 0.0 1.9 1 1 0 1 1 1 0 Large polyvalent protein associated domain 37 7TM_GPCR_Srh PF10318.9 EPE29982.1 - 0.0023 17.0 6.6 0.0023 17.0 6.6 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srh DUF1282 PF06930.12 EPE29982.1 - 1.5 8.6 14.4 0.04 13.7 6.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1282) adh_short PF00106.25 EPE29983.1 - 7e-41 139.8 0.2 1e-39 136.0 0.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE29983.1 - 4.2e-28 98.5 0.0 9.9e-28 97.3 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EPE29983.1 - 4.5e-08 32.8 0.2 5.4e-07 29.3 0.2 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EPE29983.1 - 6.1e-06 26.3 0.1 1.2e-05 25.4 0.1 1.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 EPE29983.1 - 0.0027 17.3 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EPE29983.1 - 0.003 17.1 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EPE29984.1 - 1.9e-49 167.4 0.0 4e-49 166.4 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPE29984.1 - 1.6e-15 56.9 0.0 2.5e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 EPE29984.1 - 0.0064 15.8 0.2 0.38 10.0 0.0 2.4 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HET PF06985.11 EPE29985.1 - 4.8e-25 88.6 1.3 3e-24 86.0 0.7 2.4 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF4756 PF15948.5 EPE29986.1 - 0.029 14.2 1.6 0.064 13.1 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4756) XhlA PF10779.9 EPE29986.1 - 0.11 12.7 0.1 0.42 10.9 0.1 1.9 1 0 0 1 1 1 0 Haemolysin XhlA CorA PF01544.18 EPE29986.1 - 1 8.6 8.1 2.1 7.6 7.6 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Pkinase PF00069.25 EPE29987.1 - 2.2e-18 66.6 0.0 3.6e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE29987.1 - 1.6e-07 30.9 0.0 3.3e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3425 PF11905.8 EPE29988.1 - 6.9e-21 74.5 0.1 1.9e-20 73.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EPE29988.1 - 4 7.6 8.7 9.6 6.4 8.7 1.6 1 0 0 1 1 1 0 bZIP transcription factor Glyco_hydro_3_C PF01915.22 EPE29989.1 - 4.4e-41 141.1 0.0 7.6e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE29989.1 - 6.2e-34 117.8 0.0 1.3e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE29989.1 - 9.4e-24 83.3 0.0 2.4e-23 82.0 0.0 1.7 2 0 0 2 2 2 1 Fibronectin type III-like domain ketoacyl-synt PF00109.26 EPE29990.1 - 2.7e-81 272.9 0.0 4.6e-81 272.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EPE29990.1 - 4.7e-77 259.0 0.6 4.7e-77 259.0 0.6 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EPE29990.1 - 3.4e-37 128.6 0.0 6.1e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE29990.1 - 2.2e-34 118.0 0.1 5.1e-34 116.8 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EPE29990.1 - 2.4e-32 112.9 0.0 2.1e-31 109.8 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 EPE29990.1 - 6.1e-18 64.9 9.6 1.1e-08 35.4 1.3 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 EPE29990.1 - 2.4e-12 46.7 0.0 4.8e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EPE29990.1 - 1.3e-05 25.6 0.0 3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 EPE29990.1 - 0.00013 22.7 0.4 0.038 14.6 0.0 3.5 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 EPE29990.1 - 0.0012 18.2 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_1 PF00561.20 EPE29990.1 - 0.028 14.1 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE29990.1 - 0.18 11.0 0.0 0.6 9.3 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 adh_short PF00106.25 EPE29991.1 - 1.2e-27 96.6 0.0 2e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE29991.1 - 3.1e-26 92.4 0.0 8.1e-26 91.0 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE29991.1 - 2.1e-07 31.0 0.0 3.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 EPE29991.1 - 0.0024 18.0 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF1729 PF08354.10 EPE29992.1 - 8.2e-149 495.3 0.0 1.6e-148 494.4 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EPE29992.1 - 4.3e-62 210.4 0.0 4.6e-61 207.1 0.0 2.4 3 0 0 3 3 3 1 Acyl transferase domain SAT PF16073.5 EPE29992.1 - 1.6e-30 106.6 0.1 5.4e-30 104.9 0.0 2.0 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 EPE29992.1 - 5.4e-27 93.8 0.0 1.1e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain FAS_meander PF17951.1 EPE29992.1 - 1.3e-21 76.9 0.0 3.8e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydrat_N PF13452.6 EPE29992.1 - 1.1e-08 35.3 0.0 7e-06 26.2 0.0 2.6 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase NMO PF03060.15 EPE29992.1 - 0.0031 16.9 0.0 0.05 13.0 0.0 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase FAS_N PF17828.1 EPE29992.1 - 0.14 12.2 0.1 0.33 11.0 0.1 1.6 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Fas_alpha_ACP PF18325.1 EPE29993.1 - 4.4e-56 189.7 0.1 1.2e-55 188.3 0.1 1.8 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 EPE29993.1 - 4.9e-36 124.3 0.1 1e-35 123.2 0.1 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 EPE29993.1 - 4.3e-25 88.7 0.2 8.4e-25 87.8 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EPE29993.1 - 1.1e-13 51.4 0.0 2.3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EPE29993.1 - 1e-11 44.9 0.0 4.5e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EPE29993.1 - 7.3e-09 35.4 0.0 2.4e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE29993.1 - 3.1e-05 24.0 0.2 0.00012 22.1 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EPE29993.1 - 0.018 14.5 0.0 0.047 13.1 0.0 1.7 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE29993.1 - 0.066 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 EPE29994.1 - 2.5e-41 141.8 53.7 2.5e-41 141.8 53.7 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE29994.1 - 1.2e-07 30.5 23.3 1.7e-07 30.1 23.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 EPE29994.1 - 5 7.7 8.3 4.9 7.8 5.3 2.6 2 1 0 2 2 2 0 Phage holin family 2 AflR PF08493.10 EPE29995.1 - 3.3e-18 66.2 5.6 4.8e-18 65.7 5.6 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 EPE29995.1 - 4.4e-07 29.9 11.3 9.8e-07 28.8 11.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 EPE29997.1 - 1.3e-18 67.4 0.0 7.3e-18 64.9 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPE29997.1 - 3.2e-05 23.7 0.1 0.011 15.3 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE29997.1 - 4.1e-05 23.0 0.1 0.03 13.6 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE29997.1 - 0.00039 20.6 0.0 0.0011 19.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EPE29997.1 - 0.012 16.2 0.0 0.029 14.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE29997.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FSH1 PF03959.13 EPE29998.1 - 1.7e-26 93.2 0.0 9.8e-26 90.7 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 EPE29999.1 - 2.9e-12 46.6 0.0 7.9e-12 45.2 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family p450 PF00067.22 EPE30000.1 - 4.8e-23 81.6 0.0 7.8e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 EPE30001.1 - 3.6e-22 78.7 0.0 5.3e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MLTR_LBD PF17765.1 EPE30001.1 - 0.05 13.7 0.6 11 6.1 0.3 2.6 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain YARHG PF13308.6 EPE30002.1 - 0.0078 16.1 0.2 0.026 14.4 0.2 1.9 1 0 0 1 1 1 1 YARHG domain DUF4754 PF15946.5 EPE30002.1 - 0.084 13.2 0.0 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4754) LRAT PF04970.13 EPE30003.1 - 0.15 12.4 0.3 0.31 11.3 0.3 1.6 1 1 0 1 1 1 0 Lecithin retinol acyltransferase UPF0444 PF15475.6 EPE30003.1 - 1.5 9.2 9.9 2.8 8.3 9.9 1.4 1 0 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 HET PF06985.11 EPE30004.1 - 8.7e-34 117.0 0.2 1.2e-33 116.5 0.2 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PNTB PF02233.16 EPE30005.1 - 8.1e-165 549.2 22.0 8.1e-165 549.2 22.0 2.4 2 1 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EPE30005.1 - 1.7e-66 223.6 0.1 8.2e-66 221.4 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EPE30005.1 - 2e-45 154.4 0.1 5.8e-45 152.9 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EPE30005.1 - 6.9e-30 103.3 4.0 6.9e-30 103.3 4.0 4.2 3 1 0 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EPE30005.1 - 0.0017 17.8 0.1 1.2 8.4 0.0 2.9 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EPE30005.1 - 0.026 13.7 0.1 0.063 12.5 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 EPE30005.1 - 0.058 13.1 0.5 1.4 8.7 0.1 3.0 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain DUF442 PF04273.13 EPE30005.1 - 0.096 12.8 0.1 12 6.0 0.1 2.7 2 0 0 2 2 2 0 Putative phosphatase (DUF442) PBP PF01161.20 EPE30006.1 - 3.2e-14 53.4 0.0 4.5e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FAD_binding_4 PF01565.23 EPE30009.1 - 4.8e-24 84.7 0.6 4.8e-24 84.7 0.6 1.9 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 EPE30009.1 - 2.6e-12 46.6 0.1 5e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Helicase_C PF00271.31 EPE30010.1 - 1.6e-14 54.2 0.0 3.6e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 EPE30010.1 - 6e-12 45.8 0.0 1.4e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 EPE30010.1 - 2.2e-07 30.8 0.3 4.8e-07 29.7 0.3 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EPE30010.1 - 0.0004 20.7 0.3 0.00079 19.8 0.3 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EPE30010.1 - 0.0087 15.1 0.1 0.019 14.1 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EPE30010.1 - 0.013 15.7 0.2 0.06 13.6 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EPE30010.1 - 0.025 14.3 0.1 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EPE30010.1 - 0.043 13.2 0.2 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.15 EPE30010.1 - 0.045 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 EPE30010.1 - 0.089 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain GAS2 PF02187.17 EPE30012.1 - 5.9e-07 29.5 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain RACo_linker PF17650.1 EPE30012.1 - 0.039 13.8 0.1 0.14 12.0 0.0 1.9 1 1 0 1 1 1 0 RACo linker region Aconitase PF00330.20 EPE30013.1 - 6.7e-113 378.1 0.5 6.3e-112 374.9 0.5 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EPE30013.1 - 3.4e-25 88.9 0.0 7e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain NAD_binding_4 PF07993.12 EPE30014.1 - 1.2e-34 119.7 0.1 8.1e-34 116.9 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EPE30014.1 - 1.3e-13 51.0 0.0 2.5e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EPE30014.1 - 8.9e-06 26.0 0.2 2e-05 24.9 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EPE30014.1 - 8.2e-05 21.7 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EPE30014.1 - 0.00053 19.9 0.0 0.00096 19.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EPE30014.1 - 0.0054 17.2 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EPE30014.1 - 0.083 12.3 0.1 0.25 10.7 0.1 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF604 PF04646.12 EPE30016.1 - 6.9e-07 28.9 0.0 3e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF604 Fringe PF02434.16 EPE30016.1 - 4.1e-06 26.4 0.0 9e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 Fringe-like AA_permease_2 PF13520.6 EPE30018.1 - 3.7e-45 154.5 38.1 2.3e-40 138.7 27.5 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 EPE30018.1 - 0.00018 20.3 37.7 0.0044 15.7 25.8 2.2 2 0 0 2 2 2 2 Amino acid permease DUF3112 PF11309.8 EPE30018.1 - 0.42 10.0 9.6 0.059 12.8 4.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3112) GFA PF04828.14 EPE30019.1 - 2.2e-08 34.3 0.2 3.3e-06 27.3 0.2 2.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.16 EPE30019.1 - 0.038 14.3 0.0 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Fer4_2 PF12797.7 EPE30019.1 - 0.41 10.8 2.3 2.1 8.6 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Abhydrolase_1 PF00561.20 EPE30020.1 - 3.5e-26 92.4 0.1 1.1e-23 84.2 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EPE30020.1 - 5.6e-21 74.6 0.0 1.8e-20 73.0 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein APH PF01636.23 EPE30021.1 - 2.9e-11 43.7 0.0 5.9e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE30021.1 - 7e-05 22.5 0.0 0.0002 21.0 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase SIT PF15330.6 EPE30022.1 - 0.1 13.1 0.4 6 7.3 0.0 2.8 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT DUF3328 PF11807.8 EPE30022.1 - 0.23 11.2 3.4 8.5 6.1 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3328) SecE PF00584.20 EPE30022.1 - 4.8 7.2 6.0 3 7.8 1.8 2.6 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex HET PF06985.11 EPE30023.1 - 6.8e-26 91.4 0.0 1.2e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TEP1_N PF05386.11 EPE30023.1 - 0.055 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 TEP1 N-terminal domain Peptidase_S41 PF03572.18 EPE30024.1 - 9.2e-10 38.3 0.0 2.5e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase family S41 Peptidase_S41 PF03572.18 EPE30025.1 - 1.1e-06 28.3 0.0 4.1e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase family S41 Aminotran_1_2 PF00155.21 EPE30027.1 - 2.7e-84 283.4 0.0 3.5e-84 283.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPE30027.1 - 1.9e-05 23.8 0.0 4.3e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EPE30027.1 - 4.3e-05 22.2 0.0 7.5e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EPE30027.1 - 0.00092 18.6 0.7 0.0015 17.9 0.7 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Actin PF00022.19 EPE30028.1 - 8.7e-21 74.0 0.0 7.5e-09 34.7 0.0 3.5 3 1 1 4 4 4 3 Actin Actin_micro PF17003.5 EPE30028.1 - 2.8e-06 26.8 0.2 1.4e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Putative actin-like family MreB_Mbl PF06723.13 EPE30028.1 - 0.0042 15.9 0.0 0.2 10.4 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EPE30028.1 - 0.019 15.4 0.0 0.035 14.5 0.0 1.6 1 1 0 1 1 1 0 Cell division protein FtsA Nterm_IS4 PF13006.7 EPE30029.1 - 0.061 13.5 0.0 4.6 7.5 0.0 3.0 3 0 0 3 3 3 0 Insertion element 4 transposase N-terminal AAA_assoc_2 PF16193.5 EPE30029.1 - 0.075 13.4 0.1 0.37 11.2 0.1 2.2 1 0 0 1 1 1 0 AAA C-terminal domain AAA PF00004.29 EPE30030.1 - 3.9e-21 75.9 0.0 9.9e-21 74.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE30030.1 - 0.00061 20.2 0.2 0.004 17.5 0.2 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EPE30030.1 - 0.012 15.6 0.0 0.036 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPE30030.1 - 0.024 14.9 0.1 0.17 12.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 EPE30030.1 - 0.066 13.8 0.0 0.066 13.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain RRN3 PF05327.11 EPE30030.1 - 9 4.7 23.4 0.0076 14.9 8.5 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_C14 PF00656.22 EPE30031.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Caspase domain DUF4652 PF15525.6 EPE30031.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) CLASP_N PF12348.8 EPE30031.1 - 0.19 11.3 0.1 0.6 9.6 0.1 1.7 2 0 0 2 2 2 0 CLASP N terminal MoaC PF01967.21 EPE30032.1 - 3.7e-53 179.2 3.3 1.2e-52 177.6 3.3 1.7 1 1 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 EPE30033.1 - 1.9e-35 121.6 0.0 2.2e-34 118.2 0.0 2.2 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EPE30033.1 - 3.8e-25 89.2 0.2 2.3e-24 86.6 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 EPE30033.1 - 6.7e-05 23.2 0.0 0.00029 21.1 0.0 2.0 3 0 0 3 3 3 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EPE30033.1 - 0.11 12.7 0.2 0.47 10.6 0.1 2.0 2 1 0 2 2 2 0 4Fe-4S single cluster domain FlgT_C PF16538.5 EPE30034.1 - 0.054 14.0 0.0 0.47 11.0 0.0 2.2 2 0 0 2 2 2 0 Flagellar assembly protein T, C-terminal domain PD40 PF07676.12 EPE30034.1 - 0.054 13.4 0.7 1.8 8.6 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EPE30034.1 - 0.17 9.8 1.8 9.1 4.1 0.0 2.8 2 1 0 3 3 3 0 IKI3 family Methyltransf_25 PF13649.6 EPE30035.1 - 1.3e-05 25.9 0.0 2.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EPE30035.1 - 1.3e-05 25.1 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EPE30035.1 - 0.00041 20.2 0.0 0.00057 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE30035.1 - 0.00089 19.1 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE30035.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GCD14 PF08704.10 EPE30035.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MetW PF07021.12 EPE30035.1 - 0.027 14.1 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.20 EPE30035.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PDEase_I PF00233.19 EPE30036.1 - 2.5e-69 233.6 0.0 3.6e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Not3 PF04065.15 EPE30037.1 - 0.047 13.1 0.1 0.047 13.1 0.1 2.0 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Crinivirus_P26 PF07416.11 EPE30037.1 - 0.13 11.9 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Crinivirus P26 protein DUF2312 PF10073.9 EPE30037.1 - 0.17 11.6 0.5 5.1 6.8 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF2203 PF09969.9 EPE30037.1 - 0.21 12.3 2.6 5.9 7.6 0.3 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Abhydrolase_3 PF07859.13 EPE30038.1 - 1.2e-36 126.6 0.0 1.6e-36 126.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold HcyBio PF01837.16 EPE30038.1 - 0.2 10.4 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 Homocysteine biosynthesis enzyme, sulfur-incorporation DUF4510 PF14971.6 EPE30039.1 - 0.036 14.4 0.7 0.14 12.5 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) STE3 PF02076.15 EPE30040.1 - 3.6e-68 229.9 18.0 4.4e-68 229.6 18.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF3328 PF11807.8 EPE30042.1 - 4.8e-45 154.0 0.0 5.3e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TPR_12 PF13424.6 EPE30043.1 - 9.2e-06 25.9 0.0 0.0079 16.5 0.0 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPE30043.1 - 0.0005 20.5 0.0 0.22 12.0 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EPE30043.1 - 0.00082 19.2 0.6 5.5 7.0 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPE30043.1 - 0.052 13.7 0.3 17 5.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EPE30043.1 - 0.22 12.2 0.4 10 7.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 EPE30044.1 - 5.4e-27 94.2 0.1 9.3e-15 55.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE30044.1 - 1.7e-13 49.4 0.0 0.0077 16.7 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EPE30044.1 - 3.5e-13 49.8 0.1 8.5e-06 26.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EPE30044.1 - 7.3e-12 45.2 0.3 0.0039 17.6 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EPE30044.1 - 1.1e-11 44.8 0.1 5.9e-07 29.6 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DLH PF01738.18 EPE30045.1 - 0.00011 21.8 0.1 0.0012 18.5 0.1 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EPE30045.1 - 0.0091 15.9 0.1 0.016 15.2 0.1 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 EPE30045.1 - 0.012 14.3 0.2 0.021 13.5 0.2 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF1100 PF06500.11 EPE30045.1 - 0.012 14.4 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) adh_short PF00106.25 EPE30046.1 - 2.3e-37 128.3 0.0 3.2e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE30046.1 - 8e-28 97.6 0.0 1.1e-27 97.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE30046.1 - 8.3e-05 22.6 0.1 0.00021 21.3 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE30046.1 - 0.0013 18.2 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EPE30046.1 - 0.011 15.9 0.2 0.024 14.9 0.1 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EPE30046.1 - 0.095 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SesA PF17107.5 EPE30047.1 - 0.0011 19.1 0.1 0.0011 19.1 0.1 3.0 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_16 PF13191.6 EPE30047.1 - 0.038 14.4 0.0 1.2 9.5 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 EPE30047.1 - 0.05 13.5 0.0 0.85 9.5 0.0 2.5 1 1 0 1 1 1 0 NACHT domain DUF2520 PF10728.9 EPE30047.1 - 0.077 12.8 0.0 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) ABC_tran PF00005.27 EPE30047.1 - 0.16 12.5 0.6 1.1 9.8 0.0 2.6 3 0 0 3 3 3 0 ABC transporter AAA_18 PF13238.6 EPE30047.1 - 0.16 12.5 0.0 0.72 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF1043 PF06295.12 EPE30047.1 - 1.1 9.3 5.9 0.29 11.1 1.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) adh_short PF00106.25 EPE30048.1 - 7.3e-08 32.1 0.3 2e-07 30.6 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EPE30048.1 - 0.0001 22.3 0.2 0.00019 21.4 0.0 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 EPE30048.1 - 0.0014 18.3 0.1 0.0031 17.1 0.1 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Inhibitor_G39P PF11417.8 EPE30048.1 - 0.016 15.7 0.0 0.035 14.6 0.0 1.6 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P DUF5435 PF17503.2 EPE30049.1 - 0.075 12.8 0.0 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5435) SHP PF03579.13 EPE30049.1 - 0.41 10.6 3.5 0.38 10.7 1.2 2.1 2 0 0 2 2 2 0 Small hydrophobic protein His_Phos_2 PF00328.22 EPE30050.1 - 6.1e-30 104.8 0.0 7.5e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pept_tRNA_hydro PF01195.19 EPE30051.1 - 1.1e-34 119.8 0.0 1.4e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase BAR PF03114.18 EPE30052.1 - 7.9e-66 222.1 5.2 9.5e-66 221.8 5.2 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 EPE30052.1 - 0.005 17.5 0.0 0.03 15.1 0.0 2.4 2 1 0 2 2 2 1 CP12 domain DUF2884 PF11101.8 EPE30052.1 - 0.18 11.3 3.0 1.4 8.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) FliD_N PF02465.18 EPE30052.1 - 0.93 10.2 3.7 7.8 7.3 0.2 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus SVIP PF15811.5 EPE30052.1 - 2.6 8.5 7.6 0.17 12.4 1.0 2.3 2 1 0 2 2 2 0 Small VCP/p97-interacting protein Phospholamban PF04272.14 EPE30054.1 - 0.063 12.8 0.1 0.08 12.4 0.1 1.1 1 0 0 1 1 1 0 Phospholamban Med24_N PF11277.8 EPE30055.1 - 0.13 10.3 0.2 0.16 10.0 0.2 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Glycos_transf_1 PF00534.20 EPE30056.1 - 8.8e-24 84.0 0.0 2.4e-23 82.5 0.0 1.6 1 1 1 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EPE30056.1 - 9.5e-17 61.7 0.0 2.1e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EPE30056.1 - 6.6e-12 45.8 1.5 1.2e-11 45.0 1.5 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EPE30056.1 - 1.3e-07 31.9 0.0 3.2e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EPE30056.1 - 3.3e-07 30.9 0.4 7.5e-07 29.7 0.5 1.7 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain DUF615 PF04751.14 EPE30056.1 - 0.045 13.7 0.2 1.3 8.9 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF615) GDE_C PF06202.14 EPE30057.1 - 0.033 13.1 0.0 0.15 11.0 0.0 2.2 2 1 0 2 2 2 0 Amylo-alpha-1,6-glucosidase Mito_carr PF00153.27 EPE30058.1 - 1.9e-46 155.9 0.9 3.4e-17 62.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_N PF08240.12 EPE30059.1 - 2.9e-29 101.2 1.4 5.8e-29 100.2 1.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE30059.1 - 3.8e-09 36.6 0.0 0.003 17.5 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EPE30059.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2306 PF10067.9 EPE30060.1 - 2.2e-17 63.6 4.8 4e-17 62.8 4.8 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) DUF3176 PF11374.8 EPE30061.1 - 1.2e-10 41.5 0.6 1.2e-10 41.5 0.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) DUF5071 PF16804.5 EPE30062.1 - 1.3e-39 135.1 0.3 1.8e-39 134.7 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5071) GMC_oxred_C PF05199.13 EPE30063.1 - 7.7e-10 39.5 0.6 5.6e-09 36.7 0.1 2.6 3 0 0 3 3 3 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EPE30063.1 - 4e-06 26.4 0.0 4e-05 23.2 0.0 2.5 2 1 0 2 2 2 1 GMC oxidoreductase Rhodanese PF00581.20 EPE30063.1 - 3.5e-05 24.3 0.0 4.7 7.8 0.0 3.5 3 0 0 3 3 3 2 Rhodanese-like domain FAD_binding_2 PF00890.24 EPE30063.1 - 0.00023 20.4 0.0 0.00037 19.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EPE30063.1 - 0.012 15.8 0.4 0.042 14.1 0.4 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Abhydrolase_1 PF00561.20 EPE30063.1 - 0.013 15.2 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Pyr_redox_2 PF07992.14 EPE30063.1 - 0.042 13.1 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EPE30063.1 - 0.083 12.2 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase PSY3 PF16836.5 EPE30063.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Shu complex component Psy3, DNA-binding description adh_short PF00106.25 EPE30065.1 - 1.6e-25 89.7 0.0 2e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE30065.1 - 1.1e-16 61.1 0.0 1.4e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE30065.1 - 6.3e-06 26.2 0.2 8.9e-06 25.7 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE30065.1 - 0.0041 16.6 0.0 0.007 15.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE30065.1 - 0.0081 15.6 0.0 0.021 14.2 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EPE30065.1 - 0.026 14.6 0.1 0.1 12.6 0.2 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EPE30065.1 - 0.048 13.5 0.2 0.078 12.9 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rox3 PF08633.10 EPE30066.1 - 3.4e-63 213.6 0.7 3.4e-63 213.6 0.7 1.4 2 0 0 2 2 2 1 Rox3 mediator complex subunit RRM_1 PF00076.22 EPE30067.1 - 1.2e-59 198.1 0.1 2.6e-19 68.8 0.0 5.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EPE30067.1 - 2.5e-08 34.4 0.0 2.4 8.4 0.0 6.3 4 3 2 6 6 6 2 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 EPE30067.1 - 2e-05 24.2 0.0 0.26 10.9 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 EPE30067.1 - 0.00031 20.3 1.0 0.021 14.4 0.0 3.3 3 1 0 3 3 3 1 Histone lysine methyltransferase SET associated RRM_7 PF16367.5 EPE30067.1 - 0.0013 18.8 0.1 3.4 7.9 0.0 3.6 3 0 0 3 3 3 1 RNA recognition motif NosL PF05573.12 EPE30067.1 - 0.035 14.5 0.1 0.42 11.0 0.1 2.3 2 0 0 2 2 2 0 NosL BRAP2 PF07576.12 EPE30067.1 - 0.036 14.3 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 RRM_Rrp7 PF17799.1 EPE30067.1 - 0.04 13.7 0.6 15 5.3 0.1 3.1 2 2 1 3 3 3 0 Rrp7 RRM-like N-terminal domain FAM53 PF15242.6 EPE30070.1 - 0.036 13.9 0.4 0.048 13.5 0.4 1.1 1 0 0 1 1 1 0 Family of FAM53 PRY PF13765.6 EPE30073.1 - 0.12 12.1 1.2 1.1 9.0 0.1 2.0 2 0 0 2 2 2 0 SPRY-associated domain Med5 PF08689.10 EPE30074.1 - 1.3e-29 102.8 0.0 6.5e-29 100.5 0.0 1.8 1 1 0 1 1 1 1 Mediator complex subunit Med5 Involucrin_N PF10583.9 EPE30076.1 - 0.02 15.5 2.6 0.03 14.9 2.5 1.4 1 1 0 1 1 1 0 Involucrin of squamous epithelia N-terminus DUF2076 PF09849.9 EPE30078.1 - 0.0029 17.7 1.6 0.0029 17.7 1.6 2.5 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) EAR PF07897.11 EPE30078.1 - 1.3 8.7 6.3 0.73 9.5 0.3 2.9 2 0 0 2 2 2 0 Ethylene-responsive binding factor-associated repression DUF4662 PF15578.6 EPE30078.1 - 8.3 6.1 10.5 0.35 10.6 4.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4662) Acetyltransf_10 PF13673.7 EPE30079.1 - 6.2e-09 35.9 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE30079.1 - 4.3e-07 30.2 0.0 7.3e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE30079.1 - 1.4e-05 25.4 0.0 3.4e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE30079.1 - 0.00063 19.7 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein DUF3528 PF12045.8 EPE30079.1 - 0.0025 18.5 0.0 0.0041 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) EHN PF06441.12 EPE30080.1 - 1.5e-34 118.6 0.7 2.2e-34 118.1 0.7 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EPE30080.1 - 5.3e-09 36.1 0.1 9.9e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Amidase PF01425.21 EPE30081.1 - 1.6e-79 268.0 0.0 2.2e-79 267.5 0.0 1.1 1 0 0 1 1 1 1 Amidase FAD_binding_2 PF00890.24 EPE30082.1 - 4.7e-121 404.8 5.9 6.3e-121 404.3 5.9 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EPE30082.1 - 3.8e-34 117.4 0.2 5.7e-34 116.9 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 EPE30082.1 - 5.2e-06 25.8 1.4 3.1e-05 23.3 1.4 2.0 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EPE30082.1 - 2.4e-05 23.7 0.7 0.0011 18.3 0.4 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE30082.1 - 0.0016 17.8 2.1 0.14 11.4 0.9 2.7 2 1 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EPE30082.1 - 0.0031 16.8 0.4 0.0051 16.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPE30082.1 - 0.049 13.2 1.1 0.08 12.5 1.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EPE30082.1 - 0.072 11.8 0.5 0.17 10.5 0.5 1.6 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EPE30082.1 - 0.3 10.3 5.0 1.9 7.7 1.6 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.21 EPE30083.1 - 1.2e-86 290.4 5.2 1.5e-86 290.1 5.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EPE30083.1 - 9.1e-50 167.9 0.0 2.7e-49 166.4 0.0 1.8 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Qn_am_d_aIV PF09100.10 EPE30083.1 - 0.01 15.7 0.5 0.024 14.5 0.5 1.6 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV NAD_binding_7 PF13241.6 EPE30083.1 - 0.013 15.9 0.1 0.033 14.6 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 EPE30083.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldo_ket_red PF00248.21 EPE30084.1 - 4.6e-39 134.4 0.0 4.9e-37 127.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SDH_sah PF01972.16 EPE30085.1 - 0.016 14.3 1.2 0.028 13.4 1.2 1.4 1 0 0 1 1 1 0 Serine dehydrogenase proteinase LMBR1 PF04791.16 EPE30085.1 - 1.4 7.7 3.3 2.1 7.2 3.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein SOBP PF15279.6 EPE30085.1 - 7.4 7.1 24.9 11 6.6 24.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein ELYS-bb PF16687.5 EPE30086.1 - 0.19 10.3 0.1 0.28 9.7 0.1 1.1 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin GLE1 PF07817.13 EPE30087.1 - 4.1e-49 167.0 0.0 5.4e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 GLE1-like protein Ndc1_Nup PF09531.10 EPE30087.1 - 0.026 13.2 1.9 0.035 12.8 1.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-C4H2 PF10146.9 EPE30087.1 - 0.16 12.3 6.7 0.29 11.4 6.7 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein RNB PF00773.19 EPE30088.1 - 2.6e-88 296.5 0.0 4.2e-88 295.8 0.0 1.3 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 EPE30088.1 - 3.6e-26 91.3 0.0 1.4e-25 89.5 0.0 2.1 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_Dis3 PF17849.1 EPE30088.1 - 1.5e-25 89.0 0.0 3.7e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EPE30088.1 - 4.7e-06 26.7 0.0 0.022 14.9 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 EPE30088.1 - 0.012 15.3 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Rrp44-like cold shock domain NPR3 PF03666.13 EPE30088.1 - 3.5 6.3 10.5 0.13 11.0 2.9 2.3 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Ferritin_2 PF13668.6 EPE30089.1 - 2.7e-39 134.5 0.8 4.1e-39 133.9 0.8 1.3 1 0 0 1 1 1 1 Ferritin-like domain adh_short PF00106.25 EPE30090.1 - 4.4e-21 75.2 0.0 1.7e-16 60.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE30090.1 - 1.3e-11 44.6 0.0 1.5e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE30090.1 - 0.0001 22.3 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Preseq_ALAS PF09029.10 EPE30090.1 - 0.19 12.2 0.1 0.58 10.7 0.0 1.7 2 0 0 2 2 2 0 5-aminolevulinate synthase presequence zf-MYND PF01753.18 EPE30091.1 - 0.18 11.9 2.0 0.42 10.7 2.0 1.6 1 0 0 1 1 1 0 MYND finger DUF2256 PF10013.9 EPE30091.1 - 2.1 8.5 5.2 14 5.9 5.2 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) DHO_dh PF01180.21 EPE30092.1 - 7.9e-15 54.8 0.0 1.2e-14 54.2 0.0 1.3 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 EPE30092.1 - 0.13 11.6 9.2 0.047 13.1 5.5 1.8 2 0 0 2 2 2 0 Nitronate monooxygenase ABC_tran PF00005.27 EPE30093.1 - 2.7e-48 164.0 0.0 6.8e-26 91.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPE30093.1 - 1.8e-32 113.1 8.7 1.8e-32 113.1 8.7 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.6 EPE30093.1 - 2.9e-09 37.2 0.5 0.074 12.8 0.0 3.9 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EPE30093.1 - 5.3e-08 33.2 0.0 0.0015 18.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EPE30093.1 - 4e-07 29.7 0.7 0.0079 15.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EPE30093.1 - 4.1e-07 29.7 5.8 0.029 13.8 1.8 4.5 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EPE30093.1 - 6.8e-07 29.8 0.0 0.0059 17.0 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EPE30093.1 - 1e-05 25.5 0.1 0.059 13.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase RNA_helicase PF00910.22 EPE30093.1 - 4.7e-05 23.7 0.1 0.072 13.5 0.0 2.8 3 0 0 3 3 2 1 RNA helicase NB-ARC PF00931.22 EPE30093.1 - 6.3e-05 22.3 0.0 0.17 11.0 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_14 PF13173.6 EPE30093.1 - 9.8e-05 22.4 0.0 0.015 15.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 EPE30093.1 - 0.00022 21.3 0.0 0.31 11.2 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EPE30093.1 - 0.00028 21.5 0.2 0.19 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EPE30093.1 - 0.00032 21.1 0.0 0.14 12.5 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.15 EPE30093.1 - 0.00035 19.5 0.4 0.43 9.3 0.0 2.3 2 0 0 2 2 2 2 Adenovirus IVa2 protein ATP-synt_ab PF00006.25 EPE30093.1 - 0.00037 20.2 0.1 0.063 12.9 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 EPE30093.1 - 0.00044 20.8 0.0 0.7 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EPE30093.1 - 0.00044 20.4 0.0 0.22 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EPE30093.1 - 0.0006 19.8 0.5 0.021 14.7 0.0 2.9 2 2 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EPE30093.1 - 0.00076 19.0 0.3 0.72 9.3 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region NACHT PF05729.12 EPE30093.1 - 0.0014 18.6 0.2 0.14 12.1 0.0 3.0 2 1 1 3 3 3 1 NACHT domain AAA_24 PF13479.6 EPE30093.1 - 0.0035 17.1 0.1 0.13 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EPE30093.1 - 0.0061 16.6 0.1 8.4 6.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 EPE30093.1 - 0.0089 15.8 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EPE30093.1 - 0.011 15.7 0.5 0.25 11.3 0.0 3.0 3 0 0 3 3 3 0 Rad17 P-loop domain cobW PF02492.19 EPE30093.1 - 0.012 15.2 0.1 0.59 9.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RVP_2 PF08284.11 EPE30093.1 - 0.014 15.1 0.1 0.051 13.3 0.1 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease AAA_25 PF13481.6 EPE30093.1 - 0.017 14.7 0.0 2 7.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 EPE30093.1 - 0.03 13.6 0.0 5.2 6.3 0.0 2.7 3 0 0 3 3 3 0 Septin PRK PF00485.18 EPE30093.1 - 0.033 13.9 0.4 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Viral_helicase1 PF01443.18 EPE30093.1 - 0.042 13.6 0.0 6.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Roc PF08477.13 EPE30093.1 - 0.045 14.0 0.0 17 5.7 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EPE30093.1 - 0.074 12.4 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 EPE30093.1 - 0.097 12.6 0.1 21 5.0 0.0 2.7 2 0 0 2 2 2 0 NTPase Dynamin_N PF00350.23 EPE30093.1 - 0.11 12.5 0.1 13 5.8 0.0 2.6 3 0 0 3 3 2 0 Dynamin family TsaE PF02367.17 EPE30093.1 - 0.13 12.3 0.0 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_PrkA PF08298.11 EPE30093.1 - 0.14 11.0 0.0 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_30 PF13604.6 EPE30093.1 - 0.14 11.8 0.1 4.5 7.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain ABC_ATPase PF09818.9 EPE30093.1 - 0.58 8.9 2.6 1.1 8.0 0.0 2.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 EPE30093.1 - 0.83 9.9 3.2 1.2 9.4 0.4 2.8 3 1 0 3 3 1 0 Putative exonuclease SbcCD, C subunit TauD PF02668.16 EPE30094.1 - 3.6e-54 184.4 0.6 4.2e-54 184.1 0.6 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Avidin PF01382.17 EPE30094.1 - 0.022 15.2 0.4 4.8 7.7 0.0 2.3 1 1 1 2 2 2 0 Avidin family DIOX_N PF14226.6 EPE30094.1 - 0.11 13.2 0.0 7.5 7.3 0.0 2.4 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal BRCT PF00533.26 EPE30096.1 - 6.8e-12 45.6 0.0 3e-11 43.5 0.0 2.0 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EPE30096.1 - 0.00034 20.5 0.0 0.00063 19.6 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain RR_TM4-6 PF06459.12 EPE30096.1 - 2.6 7.8 16.0 5 6.9 7.2 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2052 PF09747.9 EPE30096.1 - 2.9 8.0 15.8 1.4 9.0 5.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4611 PF15387.6 EPE30096.1 - 5 7.4 17.2 0.84 9.9 6.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CPSF100_C PF13299.6 EPE30096.1 - 5.8 7.1 15.3 9.5 6.4 3.1 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal GEN1_C PF18380.1 EPE30096.1 - 7.6 7.5 19.6 5.3 8.0 6.1 2.4 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain MFS_1 PF07690.16 EPE30099.1 - 2.1e-35 122.3 32.9 5.6e-34 117.6 33.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EPE30099.1 - 0.003 16.9 5.6 0.003 16.9 5.6 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB FMN_dh PF01070.18 EPE30100.1 - 1.3e-114 382.9 0.0 1.7e-114 382.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EPE30100.1 - 2.2e-18 66.2 0.0 4e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EPE30100.1 - 9.4e-05 21.7 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DGF-1_5 PF11038.8 EPE30100.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 NMO PF03060.15 EPE30100.1 - 0.0026 17.2 0.0 0.0048 16.3 0.0 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EPE30100.1 - 0.024 13.6 0.6 0.12 11.4 0.2 2.2 1 1 1 2 2 2 0 IMP dehydrogenase / GMP reductase domain ABC_tran PF00005.27 EPE30102.1 - 1.5e-24 87.0 0.0 2.9e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 EPE30102.1 - 1.9e-14 53.6 10.8 4.2e-14 52.5 10.8 1.6 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 EPE30102.1 - 0.0041 17.0 0.2 0.0078 16.1 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EPE30102.1 - 0.0075 16.3 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 EPE30102.1 - 0.024 14.2 0.0 0.066 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EPE30102.1 - 0.03 14.1 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SpoVIF PF14069.6 EPE30102.1 - 0.047 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Stage VI sporulation protein F Dynamin_N PF00350.23 EPE30102.1 - 0.067 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Dynamin family TILa PF12714.7 EPE30102.1 - 9 6.3 8.4 3.3 7.7 0.7 3.2 2 1 1 3 3 3 0 TILa domain Fungal_trans PF04082.18 EPE30104.1 - 1.4e-07 30.9 1.1 2.9e-07 29.8 0.4 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE30104.1 - 2.3e-06 27.6 11.2 3.6e-06 27.0 11.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLC-beta_C PF08703.10 EPE30104.1 - 0.12 12.4 0.1 0.12 12.4 0.1 1.6 2 0 0 2 2 2 0 PLC-beta C terminal NAD_binding_2 PF03446.15 EPE30105.1 - 1.1e-68 230.4 9.2 7.2e-36 123.7 1.8 2.7 3 0 0 3 3 3 2 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EPE30105.1 - 3.2e-65 217.9 3.0 3.9e-34 117.5 0.3 2.7 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase SBD_N PF07005.11 EPE30105.1 - 2.7e-59 200.7 0.0 4.9e-59 199.8 0.0 1.5 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 EPE30105.1 - 3.2e-44 151.4 1.4 1.4e-43 149.3 1.4 2.2 1 0 0 1 1 1 1 Nucleotide-binding C-terminal domain 3HCDH_N PF02737.18 EPE30105.1 - 2.3e-11 43.9 3.8 4.8e-05 23.3 0.0 2.7 3 0 0 3 3 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EPE30105.1 - 2.7e-11 43.2 0.0 0.00017 21.0 0.0 2.6 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EPE30105.1 - 1.2e-10 41.8 6.0 8.8e-05 23.0 0.2 4.2 4 1 1 5 5 4 2 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 EPE30105.1 - 1.7e-07 31.0 0.7 0.29 10.7 0.0 4.0 3 1 1 4 4 4 3 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 EPE30105.1 - 1.4e-05 25.4 0.0 0.25 11.8 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain ApbA PF02558.16 EPE30105.1 - 0.00043 20.0 0.6 0.7 9.5 0.0 2.9 2 1 0 2 2 2 2 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 EPE30105.1 - 0.00052 19.6 0.2 0.62 9.6 0.0 2.5 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, NADPH-binding domain POR PF01558.18 EPE30105.1 - 0.00062 19.9 6.3 0.014 15.5 0.2 3.9 3 1 0 3 3 3 1 Pyruvate ferredoxin/flavodoxin oxidoreductase DpaA_N PF16924.5 EPE30105.1 - 0.0028 17.7 0.0 1 9.5 0.0 2.7 2 0 0 2 2 2 1 Dipicolinate synthase subunit A N-terminal domain Shikimate_DH PF01488.20 EPE30105.1 - 0.044 13.8 0.3 5.1 7.2 0.0 3.2 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh PF00984.19 EPE30105.1 - 0.068 13.4 0.2 11 6.3 0.0 3.4 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain TrkA_N PF02254.18 EPE30105.1 - 0.089 13.1 0.1 38 4.6 0.0 3.6 3 0 0 3 3 3 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.23 EPE30105.1 - 0.096 12.7 0.8 9.8 6.1 0.0 3.2 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HTH_28 PF13518.6 EPE30105.1 - 0.54 10.4 2.4 8 6.7 0.1 2.8 2 1 0 2 2 2 0 Helix-turn-helix domain CLIP1_ZNF PF16641.5 EPE30106.1 - 1.1 9.3 2.7 4.6 7.2 0.2 2.5 2 0 0 2 2 2 0 CLIP1 zinc knuckle Ank_2 PF12796.7 EPE30107.1 - 3e-82 271.3 1.6 4.8e-20 71.9 0.0 8.0 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.30 EPE30107.1 - 2.2e-63 208.1 0.6 8.7e-07 29.1 0.1 12.7 13 0 0 13 13 13 8 Ankyrin repeat Ank_4 PF13637.6 EPE30107.1 - 8.3e-63 208.0 2.6 2e-12 47.4 0.0 9.2 5 2 3 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE30107.1 - 2.3e-59 196.7 8.4 5.6e-11 42.5 0.1 9.7 5 3 4 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE30107.1 - 2e-42 138.3 0.0 0.00092 19.5 0.0 13.1 13 0 0 13 13 13 8 Ankyrin repeat NACHT PF05729.12 EPE30107.1 - 1.5e-08 34.7 0.0 1.5e-08 34.7 0.0 2.2 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EPE30107.1 - 0.00056 20.2 0.9 0.0015 18.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPE30107.1 - 0.036 14.4 0.0 0.14 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain ANAPC4_WD40 PF12894.7 EPE30107.1 - 0.068 13.5 0.2 0.59 10.5 0.2 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Glyco_transf_90 PF05686.12 EPE30108.1 - 1.7e-13 50.2 2.4 2.7e-11 43.0 0.5 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 CAP59_mtransfer PF11735.8 EPE30110.1 - 1e-81 274.2 0.0 1.3e-81 273.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Pectinesterase PF01095.19 EPE30112.1 - 1.4e-35 122.4 3.1 2.1e-35 121.9 3.1 1.1 1 0 0 1 1 1 1 Pectinesterase ERG4_ERG24 PF01222.17 EPE30115.1 - 3.2e-129 431.5 22.6 4e-129 431.2 22.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Xan_ur_permease PF00860.20 EPE30116.1 - 3e-52 177.6 28.8 1e-51 175.8 28.8 1.8 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 EPE30116.1 - 0.0089 16.4 8.6 0.0089 16.4 8.6 3.7 2 2 1 3 3 3 2 Molybdate transporter of MFS superfamily Amidohydro_1 PF01979.20 EPE30117.1 - 1e-62 212.5 0.8 1.3e-62 212.1 0.8 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPE30117.1 - 8.3e-20 71.7 0.1 8.9e-15 55.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EPE30117.1 - 0.021 14.2 0.1 0.073 12.4 0.1 1.8 1 1 0 1 1 1 0 Adenosine/AMP deaminase DisA_N PF02457.16 EPE30117.1 - 0.12 11.9 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding TRAP_alpha PF03896.16 EPE30118.1 - 0.00014 21.2 0.0 0.0016 17.7 0.0 2.1 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit 2OG-FeII_Oxy PF03171.20 EPE30119.1 - 3.8e-16 59.4 0.1 1.3e-15 57.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EPE30119.1 - 4.3e-13 50.0 0.0 7.7e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Glyco_transf_90 PF05686.12 EPE30120.1 - 1.7e-11 43.7 0.0 1.9e-08 33.6 0.0 3.4 2 1 0 2 2 2 2 Glycosyl transferase family 90 Tmpp129 PF10272.9 EPE30120.1 - 0.16 11.2 1.1 0.27 10.5 1.1 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor OTT_1508_deam PF14441.6 EPE30121.1 - 1.5e-18 66.6 3.0 4.2e-18 65.1 3.0 1.9 1 0 0 1 1 1 1 OTT_1508-like deaminase Fungal_trans PF04082.18 EPE30121.1 - 1.1e-11 44.3 0.0 2.5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain LepB_GAP_N PF18172.1 EPE30121.1 - 0.03 14.2 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 LepB GAP domain N-terminal subdomain DPPIV_N PF00930.21 EPE30122.1 - 5.7e-107 357.5 2.5 8.1e-107 357.0 2.5 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EPE30122.1 - 1.6e-43 148.7 4.4 4.7e-43 147.1 3.4 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EPE30122.1 - 9.8e-07 28.6 0.6 1.8e-06 27.8 0.4 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 EPE30122.1 - 0.0002 21.3 0.0 0.00039 20.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE30122.1 - 0.00091 19.9 0.0 0.0047 17.6 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE30122.1 - 0.002 17.4 0.0 0.0051 16.1 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EPE30122.1 - 0.0031 17.2 0.2 0.0065 16.1 0.2 1.5 1 0 0 1 1 1 1 Putative esterase DUF2920 PF11144.8 EPE30122.1 - 0.004 16.4 0.0 0.0067 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) DLH PF01738.18 EPE30122.1 - 0.021 14.4 0.1 0.78 9.3 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family PD40 PF07676.12 EPE30122.1 - 0.035 14.1 0.9 5.5 7.1 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 EPE30122.1 - 0.043 13.4 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold p450 PF00067.22 EPE30125.1 - 1.6e-46 159.1 0.0 1.9e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sas10 PF09368.10 EPE30126.1 - 2.5e-29 101.5 9.8 2.5e-29 101.5 9.8 2.5 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EPE30126.1 - 1.4e-12 48.1 0.0 5.8e-12 46.1 0.0 2.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family BUD22 PF09073.10 EPE30126.1 - 0.0028 17.1 1.2 0.0028 17.1 1.2 3.3 1 1 2 3 3 3 1 BUD22 DUF3106 PF11304.8 EPE30126.1 - 0.025 15.0 0.7 0.075 13.5 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) VPS38 PF17649.1 EPE30126.1 - 0.38 9.6 0.9 0.6 8.9 0.9 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Glyco_hydro_18 PF00704.28 EPE30127.1 - 7e-54 183.7 0.0 9e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EPE30127.1 - 2.5e-27 95.1 137.5 1.7e-09 38.0 5.9 6.9 6 0 0 6 6 6 6 Chitin recognition protein Dscam_C PF12355.8 EPE30127.1 - 6.8 7.7 13.8 0.85 10.6 4.7 3.3 3 0 0 3 3 3 0 Down syndrome cell adhesion molecule C terminal FMN_dh PF01070.18 EPE30128.1 - 3.2e-109 365.2 0.0 3.6e-109 365.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EPE30128.1 - 0.0011 18.1 0.3 0.0023 17.0 0.2 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EPE30128.1 - 0.024 13.8 0.1 0.033 13.3 0.1 1.1 1 0 0 1 1 1 0 Conserved region in glutamate synthase His_biosynth PF00977.21 EPE30128.1 - 0.055 12.9 0.2 1.6 8.1 0.0 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein SH3_12 PF18129.1 EPE30128.1 - 0.11 12.6 0.2 0.21 11.7 0.2 1.4 1 0 0 1 1 1 0 Xrn1 SH3-like domain HET PF06985.11 EPE30129.1 - 6.6e-17 62.2 0.1 1.6e-16 60.9 0.1 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_61 PF03443.14 EPE30131.1 - 3.4e-56 190.5 1.5 3.8e-56 190.3 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DAO PF01266.24 EPE30132.1 - 1.6e-47 162.8 0.2 1.9e-47 162.6 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE30132.1 - 0.0078 16.4 0.2 0.019 15.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE30132.1 - 0.078 12.1 0.3 0.15 11.1 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 EPE30132.1 - 0.097 11.9 1.9 0.19 10.9 2.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE30132.1 - 0.13 11.5 0.3 0.26 10.5 0.3 1.5 1 1 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EPE30132.1 - 0.22 11.5 0.3 0.54 10.2 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EPE30132.1 - 0.31 10.2 1.1 8.5 5.5 0.6 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SNF2_N PF00176.23 EPE30134.1 - 6.8e-43 146.7 0.2 4.1e-23 81.7 0.1 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE30134.1 - 3.5e-13 49.9 0.0 9.2e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EPE30134.1 - 0.00051 19.9 7.8 0.0011 18.9 7.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EPE30134.1 - 0.015 15.1 6.8 0.041 13.7 6.8 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4741 PF15897.5 EPE30134.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4741) zf-RING_2 PF13639.6 EPE30134.1 - 0.23 11.8 7.1 0.61 10.5 7.1 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 EPE30134.1 - 0.31 11.1 4.7 0.77 9.8 4.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EPE30134.1 - 5.9 6.8 11.3 13 5.8 9.4 2.5 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) NACHT PF05729.12 EPE30135.1 - 4.4e-07 29.9 0.0 8.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain zf-H2C2_2 PF13465.6 EPE30135.1 - 3.3e-06 27.3 17.3 1e-05 25.7 0.6 4.3 4 0 0 4 4 4 2 Zinc-finger double domain AAA_22 PF13401.6 EPE30135.1 - 9.5e-05 22.7 0.8 0.00092 19.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPE30135.1 - 0.00017 22.0 0.1 0.011 16.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EPE30135.1 - 0.0022 18.4 0.0 0.008 16.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-C2H2 PF00096.26 EPE30135.1 - 0.0037 17.6 26.0 0.029 14.8 2.3 5.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type DUF2075 PF09848.9 EPE30135.1 - 0.0077 15.5 0.0 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 EPE30135.1 - 0.048 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zn-ribbon_8 PF09723.10 EPE30135.1 - 0.073 13.2 3.7 0.56 10.4 0.6 2.8 2 0 0 2 2 2 0 Zinc ribbon domain AAA_14 PF13173.6 EPE30135.1 - 0.086 12.9 0.0 0.5 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EPE30135.1 - 0.12 12.7 0.1 1.5 9.2 0.0 2.8 3 0 0 3 3 3 0 RNA helicase GvpL_GvpF PF06386.11 EPE30135.1 - 0.16 11.9 2.6 0.29 11.0 2.6 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF zf-C2H2_6 PF13912.6 EPE30135.1 - 0.24 11.5 13.0 2.2 8.3 1.4 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger AAA_18 PF13238.6 EPE30135.1 - 0.74 10.4 4.1 4.6 7.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain zf-C2H2_4 PF13894.6 EPE30135.1 - 1.9 9.5 23.9 0.057 14.3 1.3 5.6 5 0 0 5 5 3 0 C2H2-type zinc finger zf-met PF12874.7 EPE30135.1 - 4.8 7.7 6.3 0.92 10.0 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type APH PF01636.23 EPE30136.1 - 7.1e-09 35.9 0.0 1.4e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EPE30136.1 - 0.0015 17.5 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 EPE30136.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Sterol-sensing PF12349.8 EPE30138.1 - 1.1e-33 116.2 5.3 2.7e-33 115.0 5.3 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EPE30138.1 - 5e-07 28.2 3.9 6.8e-07 27.8 3.9 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 EPE30138.1 - 0.0072 17.1 2.4 7.2 7.7 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat MMPL PF03176.15 EPE30138.1 - 0.0076 15.2 1.1 0.017 14.1 1.1 1.6 1 0 0 1 1 1 1 MMPL family PS-DH PF14765.6 EPE30140.1 - 4.3e-67 226.5 0.0 6.6e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 EPE30140.1 - 3.4e-66 223.4 0.0 5.8e-66 222.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EPE30140.1 - 3e-60 204.4 0.0 4.5e-60 203.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EPE30140.1 - 3.9e-60 202.8 0.3 1.1e-59 201.3 0.1 2.0 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 EPE30140.1 - 1.8e-32 111.8 0.1 3.8e-32 110.8 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EPE30140.1 - 6.9e-26 90.9 0.0 1.6e-25 89.8 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EPE30140.1 - 7e-19 68.4 0.0 2.1e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EPE30140.1 - 5.9e-18 66.2 0.0 1e-16 62.2 0.0 3.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPE30140.1 - 2.5e-13 50.1 0.0 8e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EPE30140.1 - 4.6e-11 42.8 0.0 2.1e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE30140.1 - 1.8e-09 38.2 0.0 6.1e-09 36.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE30140.1 - 1.2e-08 35.5 0.0 2.9e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EPE30140.1 - 1.2e-06 28.2 0.2 2e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.6 EPE30140.1 - 1.4e-05 24.9 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 EPE30140.1 - 2.5e-05 24.1 0.3 6.8e-05 22.7 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EPE30140.1 - 0.0028 18.0 0.1 0.0083 16.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.9 EPE30140.1 - 0.049 13.4 0.0 0.4 10.4 0.0 2.4 2 0 0 2 2 2 0 Lysine methyltransferase SAT PF16073.5 EPE30140.1 - 0.063 13.0 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis ACP_syn_III PF08545.10 EPE30140.1 - 0.087 12.7 0.4 0.22 11.4 0.4 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DREV PF05219.12 EPE30140.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase p450 PF00067.22 EPE30141.1 - 1e-52 179.4 0.0 1.4e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF829 PF05705.14 EPE30142.1 - 1.1e-35 123.7 0.0 1.3e-35 123.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) TypeIII_RM_meth PF12564.8 EPE30142.1 - 0.15 12.2 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit MFS_1 PF07690.16 EPE30143.1 - 7.6e-41 140.2 62.9 1e-40 139.8 60.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE30143.1 - 1e-18 67.1 27.2 1.4e-18 66.7 27.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPE30143.1 - 4.4e-08 32.4 16.4 4.4e-08 32.4 16.4 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.22 EPE30144.1 - 2.5e-44 151.8 0.0 3.3e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SRP72 PF08492.12 EPE30144.1 - 0.23 11.9 1.1 0.47 10.9 1.1 1.5 1 0 0 1 1 1 0 SRP72 RNA-binding domain AA_permease_2 PF13520.6 EPE30145.1 - 1.8e-48 165.4 59.9 2.2e-48 165.1 59.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE30145.1 - 3.2e-26 92.0 54.8 4.3e-25 88.2 54.8 1.9 1 1 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 EPE30145.1 - 6.5 6.8 7.5 0.39 10.7 0.4 2.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif MFS_1 PF07690.16 EPE30146.1 - 3.4e-44 151.2 48.5 4.8e-44 150.7 48.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TPR_12 PF13424.6 EPE30146.1 - 2.8e-19 69.2 2.6 1.1e-05 25.7 0.0 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EPE30146.1 - 8.7e-14 50.9 0.1 5.7e-06 26.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Sugar_tr PF00083.24 EPE30146.1 - 2.9e-13 49.5 14.9 2.9e-13 49.5 14.9 3.3 3 1 0 3 3 3 2 Sugar (and other) transporter NB-ARC PF00931.22 EPE30146.1 - 2.5e-05 23.6 0.0 0.068 12.3 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.6 EPE30146.1 - 0.0017 18.7 0.0 0.0041 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPE30146.1 - 0.008 16.6 0.1 0.029 14.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain MFS_1_like PF12832.7 EPE30146.1 - 0.019 13.8 30.2 0.15 10.9 8.4 2.2 2 0 0 2 2 2 0 MFS_1 like family TPR_7 PF13176.6 EPE30146.1 - 0.13 12.3 0.1 48 4.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MARVEL PF01284.23 EPE30147.1 - 4.6e-09 36.4 7.3 8.6e-09 35.6 7.3 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 EPE30147.1 - 0.046 12.0 0.8 0.06 11.6 0.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HAD_2 PF13419.6 EPE30148.1 - 7.6e-11 42.4 0.1 0.0022 18.1 0.0 3.3 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPE30148.1 - 1.8e-05 24.7 0.0 6e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EPE30148.1 - 4.4e-05 23.9 0.1 0.43 10.8 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase GMC_oxred_N PF00732.19 EPE30149.1 - 3.2e-31 108.8 0.0 1.4e-22 80.5 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE30149.1 - 1.3e-30 106.8 0.0 2.6e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EPE30149.1 - 6.1e-05 22.3 1.5 0.00072 18.8 0.2 2.9 4 0 0 4 4 4 1 FAD binding domain DAO PF01266.24 EPE30149.1 - 0.0011 18.6 2.7 0.0022 17.6 1.3 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE30149.1 - 0.0012 18.1 0.1 0.014 14.6 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE30149.1 - 0.0014 18.0 0.2 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE30149.1 - 0.0015 17.7 0.0 0.022 13.8 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPE30149.1 - 0.0017 18.5 0.7 0.004 17.4 0.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EPE30149.1 - 0.02 14.9 0.0 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EPE30149.1 - 0.028 13.1 0.1 0.2 10.3 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EPE30149.1 - 0.041 13.1 0.0 0.067 12.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 EPE30149.1 - 0.041 14.1 0.4 0.21 11.8 0.2 2.1 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.14 EPE30149.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase DUF3533 PF12051.8 EPE30151.1 - 0.02 13.9 0.7 0.029 13.3 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) adh_short PF00106.25 EPE30152.1 - 2.8e-15 56.3 0.1 3.8e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE30152.1 - 4.6e-13 49.3 0.1 1.1e-12 48.0 0.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EPE30152.1 - 0.011 15.6 0.0 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding DUF4202 PF13875.6 EPE30156.1 - 6e-73 244.7 0.0 6.8e-73 244.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Ank_2 PF12796.7 EPE30157.1 - 6.4e-23 81.1 0.1 2.5e-05 24.8 0.0 4.8 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE30157.1 - 5.4e-14 52.4 6.1 0.76 10.4 0.0 7.5 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE30157.1 - 5.3e-09 36.2 3.4 0.18 12.2 0.0 5.6 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE30157.1 - 8.4e-08 31.9 10.3 1.8 9.4 0.0 8.9 10 0 0 10 10 10 1 Ankyrin repeat Ank PF00023.30 EPE30157.1 - 0.00021 21.6 11.5 1 9.9 0.0 7.7 9 0 0 9 9 9 2 Ankyrin repeat DHDPS PF00701.22 EPE30158.1 - 8.3e-32 110.0 0.0 1.1e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.22 EPE30159.1 - 3.3e-09 37.6 1.1 1.5e-08 35.5 1.1 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Syntaxin PF00804.25 EPE30160.1 - 0.1 12.2 0.1 0.1 12.2 0.1 3.3 3 0 0 3 3 3 0 Syntaxin Chromo PF00385.24 EPE30160.1 - 0.23 11.4 4.2 0.9 9.5 2.6 2.6 1 1 1 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain AT_hook PF02178.19 EPE30160.1 - 9.3 6.5 9.7 33 4.8 9.7 2.0 1 0 0 1 1 1 0 AT hook motif Ank_3 PF13606.6 EPE30161.1 - 6.6e-13 47.6 8.6 0.035 14.7 0.0 8.4 8 0 0 8 8 8 3 Ankyrin repeat Ank_2 PF12796.7 EPE30161.1 - 6.5e-11 42.7 0.7 0.9 10.2 0.0 5.5 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE30161.1 - 1.6e-10 41.0 2.8 1.2 9.6 0.0 6.6 6 1 0 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPE30161.1 - 1e-09 38.7 1.5 0.032 14.8 0.1 5.9 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 EPE30161.1 - 5.3e-05 23.5 11.2 14 6.4 0.0 6.5 7 0 0 7 7 7 4 Ankyrin repeat Glyco_transf_8 PF01501.20 EPE30162.1 - 0.018 14.6 0.7 0.043 13.4 0.7 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 8 FtsH_ext PF06480.15 EPE30162.1 - 0.024 15.0 0.1 0.048 14.0 0.1 1.5 1 1 0 1 1 1 0 FtsH Extracellular Mannosyl_trans3 PF11051.8 EPE30162.1 - 0.051 12.9 0.1 0.086 12.2 0.1 1.4 1 1 0 1 1 1 0 Mannosyltransferase putative Rit1_C PF17184.4 EPE30163.1 - 1.5e-65 221.4 0.0 8.1e-52 176.3 0.0 2.1 2 0 0 2 2 2 2 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EPE30163.1 - 6.3e-37 126.2 0.0 1.6e-36 125.0 0.0 1.7 2 0 0 2 2 2 1 Rit1 DUSP-like domain Hexapep_2 PF14602.6 EPE30164.1 - 3.2e-13 49.2 7.1 2e-11 43.4 4.1 3.5 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EPE30164.1 - 1.8e-12 46.5 8.2 1.2e-10 40.6 3.2 3.4 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 EPE30164.1 - 2.4e-07 30.9 0.0 3.7e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Nop16 PF09420.10 EPE30165.1 - 9.1e-69 231.7 4.8 1e-68 231.5 4.8 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 EHN PF06441.12 EPE30165.1 - 0.099 13.0 0.8 0.22 11.9 0.8 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Pkinase PF00069.25 EPE30166.1 - 1.2e-55 188.7 0.3 6.3e-35 120.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE30166.1 - 7.4e-36 123.8 0.0 3e-35 121.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE30166.1 - 0.0002 20.8 0.0 0.00057 19.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EPE30166.1 - 0.065 13.1 0.2 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Epiglycanin_TR PF05647.11 EPE30166.1 - 0.22 11.4 6.8 0.53 10.2 6.8 1.6 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like TPD52 PF04201.15 EPE30166.1 - 0.23 11.0 9.5 0.13 11.9 6.4 2.0 2 0 0 2 2 2 0 Tumour protein D52 family FapA PF03961.13 EPE30166.1 - 0.33 9.5 3.0 0.55 8.8 3.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3896 PF13035.6 EPE30166.1 - 3.8 7.7 7.8 1.9 8.7 0.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) Fungal_trans_2 PF11951.8 EPE30167.1 - 2.9e-48 164.6 0.4 2.3e-47 161.6 0.4 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE30167.1 - 1.2e-06 28.5 7.7 2.8e-06 27.3 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE30168.1 - 1.1e-06 28.0 0.0 2.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAN_1 PF00024.26 EPE30169.1 - 0.005 16.8 0.8 0.01 15.8 0.8 1.6 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 EPE30169.1 - 0.0079 16.3 2.4 0.014 15.5 1.0 2.0 1 1 1 2 2 2 1 PAN-like domain PAN_4 PF14295.6 EPE30169.1 - 0.0092 15.9 0.3 0.02 14.8 0.3 1.5 1 0 0 1 1 1 1 PAN domain Methyltransf_23 PF13489.6 EPE30170.1 - 5.8e-14 52.3 0.0 7.4e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE30170.1 - 8.2e-13 48.8 0.0 1.4e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE30170.1 - 1.8e-11 44.6 0.0 3.6e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE30170.1 - 6.7e-10 39.0 0.0 9.6e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE30170.1 - 1.4e-07 31.1 0.0 1.1e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EPE30170.1 - 1.5e-06 28.9 0.0 2.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EPE30170.1 - 0.021 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EPE30170.1 - 0.032 13.5 0.0 0.18 11.1 0.0 2.0 1 1 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 EPE30170.1 - 0.033 13.8 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain SIS_2 PF13580.6 EPE30170.1 - 0.089 12.8 0.6 4.8 7.2 0.1 2.6 2 0 0 2 2 2 0 SIS domain Acetyltransf_10 PF13673.7 EPE30171.1 - 5.6e-10 39.2 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE30171.1 - 7.5e-10 39.1 0.1 9.8e-10 38.7 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE30171.1 - 1.3e-09 38.4 0.0 1.9e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPE30171.1 - 0.0052 16.9 0.2 0.017 15.2 0.0 1.9 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE30171.1 - 0.09 12.8 0.0 0.28 11.2 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein YccJ PF13993.6 EPE30171.1 - 0.11 12.8 0.1 0.76 10.1 0.0 2.2 2 0 0 2 2 2 0 YccJ-like protein HPIP_like PF18524.1 EPE30172.1 - 0.065 13.0 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 High potential iron-sulfur protein like Aldedh PF00171.22 EPE30173.1 - 4.2e-181 602.5 0.2 4.8e-181 602.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EPE30173.1 - 0.002 17.6 0.1 0.085 12.3 0.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1487) Rotamase_2 PF13145.6 EPE30173.1 - 0.039 14.8 0.1 0.077 13.8 0.1 1.5 1 0 0 1 1 1 0 PPIC-type PPIASE domain EMP24_GP25L PF01105.24 EPE30174.1 - 0.0079 16.2 0.5 0.011 15.6 0.5 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD bZIP_2 PF07716.15 EPE30174.1 - 0.024 14.7 13.3 0.048 13.7 13.3 1.5 1 0 0 1 1 1 0 Basic region leucine zipper SGL PF08450.12 EPE30175.1 - 5e-68 229.3 0.5 5.9e-68 229.1 0.5 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 EPE30175.1 - 1 9.8 2.9 9.2 6.9 0.1 3.3 3 0 0 3 3 3 0 Two component regulator propeller Prothymosin PF03247.14 EPE30178.1 - 0.0068 16.9 2.7 0.011 16.2 2.7 1.4 1 0 0 1 1 1 1 Prothymosin/parathymosin family DUF4695 PF15766.5 EPE30178.1 - 0.071 13.3 0.5 0.071 13.3 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4695) PDE4_UCR PF18100.1 EPE30178.1 - 0.083 13.5 1.5 0.12 13.0 0.2 1.9 2 1 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) DAO PF01266.24 EPE30179.1 - 3.6e-69 234.0 0.1 4.1e-69 233.8 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE30179.1 - 6.5e-06 26.3 0.1 1.6e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE30179.1 - 8.4e-06 25.2 0.3 0.0029 16.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE30179.1 - 0.00076 20.0 0.3 0.016 15.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EPE30179.1 - 0.00092 18.2 0.3 0.0065 15.4 0.3 1.9 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 EPE30179.1 - 0.012 14.8 0.7 0.21 10.6 0.2 2.3 2 1 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 EPE30179.1 - 0.014 14.7 0.1 0.027 13.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Mqo PF06039.15 EPE30179.1 - 0.015 13.9 0.0 1.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) MCRA PF06100.11 EPE30179.1 - 0.027 13.3 0.1 0.047 12.5 0.1 1.3 1 0 0 1 1 1 0 MCRA family NAD_binding_9 PF13454.6 EPE30179.1 - 0.11 12.5 0.6 1.5 8.8 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EPE30179.1 - 0.12 12.6 0.3 3.5 7.9 0.1 2.6 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Arc PF03869.14 EPE30179.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Arc-like DNA binding domain GSHPx PF00255.19 EPE30180.1 - 3e-41 139.4 0.0 4.1e-41 138.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 EPE30180.1 - 0.006 16.3 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EPE30180.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA family SKG6 PF08693.10 EPE30182.1 - 0.029 13.8 2.6 0.071 12.5 2.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain stn_TNFRSF12A PF12191.8 EPE30182.1 - 0.037 14.2 0.2 0.06 13.6 0.2 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Amnionless PF14828.6 EPE30182.1 - 0.075 11.9 0.0 0.097 11.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless PIRT PF15099.6 EPE30182.1 - 3.6 7.2 6.0 4.5 6.9 1.4 2.4 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family BUD22 PF09073.10 EPE30183.1 - 0.0027 17.1 16.5 0.0029 17.0 16.5 1.1 1 0 0 1 1 1 1 BUD22 Metallophos PF00149.28 EPE30184.1 - 2.5e-08 34.7 0.1 4.1e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPE30184.1 - 1.2e-05 25.6 0.3 0.0017 18.6 0.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GCV_H PF01597.19 EPE30184.1 - 0.076 12.9 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Glycine cleavage H-protein Ank_2 PF12796.7 EPE30185.1 - 1e-21 77.3 6.5 3.5e-06 27.5 0.0 7.5 5 2 2 7 7 7 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE30185.1 - 5.5e-16 58.7 6.1 0.0021 18.6 0.0 9.6 7 2 3 11 11 11 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE30185.1 - 9.5e-10 38.5 3.5 1.9 8.9 0.0 7.8 5 2 2 7 7 7 3 Ankyrin repeats (many copies) NACHT_N PF17100.5 EPE30185.1 - 1.3e-09 38.3 9.4 1.7e-09 37.8 7.0 2.3 2 1 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Ank_3 PF13606.6 EPE30185.1 - 2.9e-05 24.1 14.4 42 5.2 0.0 10.0 11 0 0 11 11 11 0 Ankyrin repeat NACHT PF05729.12 EPE30185.1 - 5.3e-05 23.2 0.0 0.00043 20.2 0.0 2.4 1 1 0 1 1 1 1 NACHT domain Ank PF00023.30 EPE30185.1 - 6.4e-05 23.2 22.9 0.5 10.9 0.0 9.3 11 1 0 11 11 11 3 Ankyrin repeat AAA_16 PF13191.6 EPE30185.1 - 0.0016 18.9 0.0 0.0063 16.9 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EPE30185.1 - 0.13 12.7 0.0 2 8.8 0.0 2.8 3 0 0 3 3 3 0 RNA helicase KAP_NTPase PF07693.14 EPE30185.1 - 0.67 9.1 3.0 1.8 7.7 0.5 2.3 1 1 0 2 2 2 0 KAP family P-loop domain Methyltransf_28 PF02636.17 EPE30186.1 - 2.6e-81 273.1 0.0 3.3e-81 272.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.25 EPE30187.1 - 8.3e-61 205.6 0.0 1.3e-60 205.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE30187.1 - 2.9e-27 95.6 0.0 5.2e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EPE30187.1 - 0.025 13.5 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 EPE30187.1 - 0.044 13.1 0.0 0.044 13.1 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 EPE30187.1 - 0.06 12.7 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPE30187.1 - 0.13 12.2 2.3 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family LCD1 PF09798.9 EPE30187.1 - 0.15 10.5 3.8 0.2 10.1 3.8 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein MAJIN PF15077.6 EPE30187.1 - 1.3 8.8 3.9 2.3 8.0 3.9 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF4887 PF16228.5 EPE30187.1 - 1.9 8.6 11.1 2.7 8.2 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) Rrn6 PF10214.9 EPE30187.1 - 2.4 6.5 8.5 3.4 6.0 8.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Rtf2 PF04641.12 EPE30187.1 - 4.5 6.6 9.5 7.6 5.8 9.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger SOG2 PF10428.9 EPE30188.1 - 0.36 10.0 6.0 0.39 9.9 6.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1180 PF06679.12 EPE30188.1 - 0.49 10.8 4.9 0.84 10.0 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) MSA-2c PF12238.8 EPE30188.1 - 9.5 6.2 8.4 17 5.3 8.4 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Glyco_transf_90 PF05686.12 EPE30189.1 - 8.4e-19 67.7 8.6 1.5e-15 57.1 7.0 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 ABA_GPCR PF12430.8 EPE30190.1 - 7.3e-58 195.3 4.3 7.3e-58 195.3 4.3 1.9 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EPE30190.1 - 2.7e-27 94.6 0.1 5.7e-26 90.4 0.0 2.5 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal DNA_pol_B_N PF18094.1 EPE30191.1 - 0.02 15.4 0.0 0.075 13.6 0.0 2.0 1 0 0 1 1 1 0 DNA polymerase beta N-terminal domain Peptidase_M9 PF01752.17 EPE30191.1 - 0.06 12.6 0.6 0.086 12.1 0.6 1.2 1 0 0 1 1 1 0 Collagenase CDH-cyt PF16010.5 EPE30192.1 - 4.3e-24 85.2 4.6 7.5e-24 84.4 4.6 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EPE30192.1 - 4.7e-05 23.5 7.4 0.00012 22.2 7.4 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 EPE30192.1 - 0.00057 20.1 0.1 0.0014 18.9 0.1 1.7 1 1 0 1 1 1 1 DOMON domain DUF2306 PF10067.9 EPE30192.1 - 0.089 13.0 15.3 0.089 13.0 2.3 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) zf-LSD1 PF06943.12 EPE30192.1 - 0.1 12.5 0.5 7.7 6.5 0.8 2.4 2 0 0 2 2 2 0 LSD1 zinc finger DUF2427 PF10348.9 EPE30192.1 - 0.32 10.8 9.6 0.081 12.7 5.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) ABC2_membrane PF01061.24 EPE30192.1 - 1.1 8.6 14.9 0.63 9.4 11.0 2.1 2 0 0 2 2 2 0 ABC-2 type transporter Paf67 PF10255.9 EPE30193.1 - 4.6e-157 523.2 0.0 5.3e-157 523.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 EPE30193.1 - 0.028 14.5 0.0 0.15 12.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Usp PF00582.26 EPE30194.1 - 4.8e-14 53.1 0.0 1.4e-13 51.6 0.0 1.8 2 0 0 2 2 2 1 Universal stress protein family Pkinase PF00069.25 EPE30195.1 - 1.5e-61 208.1 0.0 2.8e-61 207.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE30195.1 - 8.7e-36 123.5 0.0 4.2e-35 121.3 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE30195.1 - 3.4e-06 26.6 0.0 5.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EPE30195.1 - 7.9e-05 21.6 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DEAD PF00270.29 EPE30196.1 - 1.1e-40 139.3 0.0 2e-40 138.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE30196.1 - 1.1e-28 99.8 0.0 3.3e-28 98.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE30196.1 - 3.4e-06 27.2 0.0 6.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EPE30196.1 - 0.0018 17.0 0.0 0.0027 16.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 EPE30196.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase DNA_pol_phi PF04931.13 EPE30196.1 - 6.3 4.8 4.8 9.5 4.2 4.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Methyltransf_23 PF13489.6 EPE30197.1 - 2e-11 44.0 0.0 3.5e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE30197.1 - 6.8e-05 22.7 0.0 0.00097 19.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE30197.1 - 0.00013 22.6 0.0 0.0012 19.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE30197.1 - 0.00024 21.8 0.0 0.0021 18.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EPE30197.1 - 0.00049 19.1 0.0 0.0094 14.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_11 PF08241.12 EPE30197.1 - 0.0014 19.2 0.0 0.013 16.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPE30197.1 - 0.016 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain ABM PF03992.16 EPE30198.1 - 1.5e-14 53.9 0.0 1.8e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SAD_SRA PF02182.17 EPE30199.1 - 7.6e-09 35.4 0.2 1e-07 31.8 0.0 2.2 1 1 0 2 2 2 1 SAD/SRA domain DUF2716 PF10898.8 EPE30199.1 - 0.22 11.9 1.5 24 5.3 0.2 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2716) TruD PF01142.18 EPE30200.1 - 4.7e-62 210.1 0.2 2.8e-56 191.1 0.3 4.2 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) DUF1797 PF08796.10 EPE30200.1 - 0.22 11.6 0.4 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) CDO_I PF05995.12 EPE30201.1 - 1.9e-41 141.2 0.0 2.3e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 EPE30201.1 - 0.054 12.9 0.2 0.081 12.4 0.2 1.7 1 1 0 1 1 1 0 PCO_ADO Auxin_BP PF02041.16 EPE30201.1 - 0.068 12.8 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein Rotamase_3 PF13616.6 EPE30202.1 - 5e-13 49.6 0.1 9.5e-13 48.7 0.1 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EPE30202.1 - 6.4e-13 49.5 0.1 8.8e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EPE30202.1 - 0.0013 19.6 0.1 0.0017 19.2 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain Ribosomal_L7Ae PF01248.26 EPE30203.1 - 1.6e-27 95.1 1.0 2.2e-27 94.6 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EPE30203.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 PELOTA RNA binding domain LPD7 PF18821.1 EPE30203.1 - 0.11 12.7 0.0 9.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 Ribosomal_S8 PF00410.19 EPE30204.1 - 1.5e-21 76.6 0.1 2.1e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Fe-S_assembly PF04384.13 EPE30204.1 - 0.16 12.6 0.0 0.28 11.8 0.0 1.4 1 1 0 1 1 1 0 Iron-sulphur cluster assembly TraK PF06586.11 EPE30207.1 - 0.041 13.6 0.8 0.055 13.2 0.8 1.1 1 0 0 1 1 1 0 TraK protein Peptidase_M41 PF01434.18 EPE30208.1 - 4.2e-68 229.0 0.0 7.2e-68 228.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EPE30208.1 - 7.7e-42 142.8 0.0 1.8e-41 141.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPE30208.1 - 9.4e-12 44.6 0.1 2.5e-11 43.2 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EPE30208.1 - 1e-07 32.3 0.0 2.8e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 EPE30208.1 - 0.0004 20.4 0.0 0.0015 18.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPE30208.1 - 0.0016 18.8 0.1 0.11 12.8 0.1 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EPE30208.1 - 0.011 16.0 0.1 1.1 9.5 0.1 2.9 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 EPE30208.1 - 0.013 15.3 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EPE30208.1 - 0.02 14.1 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_2 PF07724.14 EPE30208.1 - 0.033 14.3 0.0 0.096 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EPE30208.1 - 0.044 13.5 0.0 0.099 12.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EPE30208.1 - 0.085 12.4 0.2 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 EPE30209.1 - 2.7e-25 88.9 0.0 9.8e-25 87.1 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE30209.1 - 3e-10 40.0 11.7 6.1e-10 39.1 11.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ORC6 PF05460.13 EPE30209.1 - 0.15 11.3 1.3 0.29 10.4 1.3 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Abhydrolase_6 PF12697.7 EPE30211.1 - 7.6e-05 23.4 0.3 0.0002 22.0 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 EPE30211.1 - 0.0022 17.5 0.0 0.006 16.1 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EPE30211.1 - 0.0028 17.0 0.0 0.0056 16.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EPE30211.1 - 0.0078 16.0 1.0 0.056 13.1 0.3 2.2 1 1 1 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.20 EPE30211.1 - 0.011 15.4 0.0 0.28 10.8 0.0 2.6 3 0 0 3 3 3 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 EPE30211.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Macoilin PF09726.9 EPE30211.1 - 0.29 9.7 8.9 0.55 8.7 8.9 1.4 1 0 0 1 1 1 0 Macoilin family AbiH PF14253.6 EPE30211.1 - 1.8 8.4 4.3 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH HCO3_cotransp PF00955.21 EPE30212.1 - 3e-78 263.9 14.5 9.4e-44 150.1 6.6 2.1 1 1 1 2 2 2 2 HCO3- transporter family FAD_binding_4 PF01565.23 EPE30213.1 - 1.3e-14 54.1 0.0 2.3e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HET-s_218-289 PF11558.8 EPE30213.1 - 0.17 11.9 0.2 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Het-s 218-289 A_deaminase PF00962.22 EPE30214.1 - 1.5e-43 149.4 0.0 5.5e-43 147.5 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 EPE30214.1 - 0.0073 15.7 0.0 0.085 12.2 0.0 2.3 2 1 1 3 3 3 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPE30214.1 - 0.04 13.4 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family Radical_SAM PF04055.21 EPE30214.1 - 0.043 14.2 0.1 0.7 10.3 0.1 2.6 1 1 2 3 3 3 0 Radical SAM superfamily FA_desaturase_2 PF03405.14 EPE30214.1 - 0.052 12.4 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 Fatty acid desaturase DHquinase_I PF01487.15 EPE30214.1 - 0.08 13.2 0.0 0.5 10.6 0.0 1.8 1 1 1 2 2 2 0 Type I 3-dehydroquinase MFS_1 PF07690.16 EPE30215.1 - 2.1e-30 105.9 23.2 3e-30 105.3 23.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EPE30215.1 - 2.8e-07 30.2 0.4 2.8e-07 30.2 0.4 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2487 PF10673.9 EPE30215.1 - 0.2 11.7 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) Paf1 PF03985.13 EPE30219.1 - 3.9e-85 286.4 1.6 4.4e-85 286.2 1.6 1.0 1 0 0 1 1 1 1 Paf1 VPS9 PF02204.18 EPE30220.1 - 1.1e-25 89.8 0.1 2.1e-25 89.0 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EPE30220.1 - 0.0089 16.3 0.4 0.039 14.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) PXA PF02194.15 EPE30220.1 - 0.043 13.8 1.0 0.079 12.9 1.0 1.3 1 0 0 1 1 1 0 PXA domain Lipase_3 PF01764.25 EPE30221.1 - 9.9e-05 22.2 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EPE30221.1 - 0.026 13.8 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ECH_1 PF00378.20 EPE30222.1 - 4.4e-73 245.7 0.0 5e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPE30222.1 - 2.3e-36 126.0 0.3 3.4e-33 115.5 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Rer1 PF03248.13 EPE30223.1 - 4.3e-79 264.2 4.2 4.9e-79 264.0 4.2 1.0 1 0 0 1 1 1 1 Rer1 family Glyco_hydr_30_2 PF14587.6 EPE30224.1 - 7.7e-20 71.8 3.2 3.6e-17 63.0 3.2 2.6 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 EPE30224.1 - 8.6e-16 58.0 1.9 1.8e-15 57.0 1.9 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 EPE30224.1 - 9.5e-15 54.6 2.1 5.2e-14 52.2 2.1 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 EPE30224.1 - 9.7e-11 41.2 0.1 1.4e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain DUF3328 PF11807.8 EPE30225.1 - 4.9e-53 180.2 0.2 6.1e-53 179.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TRAP_beta PF05753.14 EPE30225.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.6 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) TPR_14 PF13428.6 EPE30227.1 - 7.2e-09 35.7 8.2 0.0044 17.7 0.2 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 EPE30227.1 - 9e-09 34.9 0.3 0.37 11.1 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPE30227.1 - 3.8e-06 27.3 0.3 0.035 14.6 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EPE30227.1 - 1.1e-05 25.1 6.6 0.071 13.3 0.1 7.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.6 EPE30227.1 - 3.8e-05 24.0 0.4 0.22 12.2 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EPE30227.1 - 0.00014 21.5 0.1 4.8 7.2 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPE30227.1 - 0.00019 22.0 3.6 8.7 7.1 0.0 5.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPE30227.1 - 0.00033 20.8 0.4 0.017 15.5 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EPE30227.1 - 0.0012 19.0 5.3 34 4.8 0.0 7.2 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 EPE30227.1 - 0.0014 19.0 2.1 1.5 9.7 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EPE30227.1 - 0.011 15.7 0.4 11 6.3 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat RIX1 PF08167.12 EPE30228.1 - 8.9e-58 195.1 4.9 1.1e-57 194.8 3.4 1.9 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis peroxidase PF00141.23 EPE30229.1 - 3.9e-27 95.4 0.1 5.9e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 EPE30229.1 - 0.027 14.4 0.0 0.059 13.3 0.0 1.6 1 0 0 1 1 1 0 Fungal peroxidase extension region Glyco_transf_54 PF04666.13 EPE30230.1 - 1.8e-08 33.6 0.1 6.6e-06 25.2 0.1 2.2 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region F5_F8_type_C PF00754.25 EPE30231.1 - 4.5e-05 23.6 0.9 8.7e-05 22.6 0.2 1.9 2 0 0 2 2 2 1 F5/8 type C domain Glyco_hydro_43 PF04616.14 EPE30232.1 - 2e-64 217.7 13.4 2.2e-56 191.3 1.8 2.8 2 1 1 3 3 3 3 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 EPE30232.1 - 1.8e-08 34.3 0.5 0.00079 19.1 0.0 3.3 3 1 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Pkinase PF00069.25 EPE30234.1 - 2.4e-23 82.9 0.0 5.2e-11 42.4 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE30234.1 - 1.9e-09 37.2 0.0 0.00014 21.3 0.0 2.2 2 1 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 EPE30234.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family HeLo PF14479.6 EPE30235.1 - 5.7e-09 36.1 0.1 6e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation RF-1 PF00472.20 EPE30235.1 - 0.09 12.7 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 RF-1 domain MAPEG PF01124.18 EPE30236.1 - 3.9e-12 46.2 0.3 5.4e-12 45.7 0.3 1.1 1 0 0 1 1 1 1 MAPEG family DUF1996 PF09362.10 EPE30237.1 - 2.1e-83 279.9 0.5 2.6e-83 279.6 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) NMT1 PF09084.11 EPE30238.1 - 7.5e-11 42.4 0.1 1.2e-10 41.7 0.1 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_3 PF16868.5 EPE30238.1 - 3.3e-05 23.5 0.1 5.5e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 EPE30238.1 - 0.00042 19.8 0.0 0.00092 18.7 0.0 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 FAD_binding_5 PF00941.21 EPE30238.1 - 0.052 13.3 0.1 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain in molybdopterin dehydrogenase Phosphonate-bd PF12974.7 EPE30238.1 - 0.054 13.1 0.1 0.081 12.5 0.1 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Ligase_CoA PF00549.19 EPE30238.1 - 0.1 12.4 0.5 0.41 10.5 0.1 2.1 2 1 1 3 3 3 0 CoA-ligase MARVEL PF01284.23 EPE30239.1 - 1.3e-06 28.4 14.7 2e-06 27.9 14.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain PTR2 PF00854.21 EPE30241.1 - 1.1e-48 166.0 7.2 1.5e-48 165.6 7.2 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EPE30241.1 - 1.9e-10 40.2 29.3 4.3e-08 32.5 28.1 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF2649 PF10854.8 EPE30241.1 - 0.052 13.9 2.3 0.056 13.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) Prefoldin_3 PF13758.6 EPE30242.1 - 4.4e-33 113.3 0.7 4.4e-33 113.3 0.7 1.9 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.7 EPE30242.1 - 1.5e-30 105.8 1.4 2.7e-27 95.4 0.0 3.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3835) UAA PF08449.11 EPE30243.1 - 6.9e-43 147.0 10.2 1.2e-42 146.2 10.2 1.3 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EPE30243.1 - 2.6e-07 30.1 2.4 0.00043 19.6 0.1 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 EPE30243.1 - 2.2e-06 27.9 4.6 2.2e-06 27.9 4.6 3.5 4 0 0 4 4 4 2 EamA-like transporter family TPT PF03151.16 EPE30243.1 - 1.9 7.7 9.1 0.51 9.6 1.9 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family Cofilin_ADF PF00241.20 EPE30244.1 - 2.8e-25 88.4 0.0 3.2e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein KH_1 PF00013.29 EPE30245.1 - 2.7e-41 139.2 11.9 1.2e-16 60.3 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EPE30245.1 - 5.2e-10 39.0 7.9 0.018 14.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EPE30245.1 - 5.1e-09 35.9 4.2 0.02 14.8 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EPE30245.1 - 5.1e-05 23.3 5.3 0.26 11.4 0.1 3.4 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 EPE30245.1 - 0.0087 16.0 0.1 7.4 6.7 0.1 2.7 3 0 0 3 3 3 2 KH-like RNA-binding domain RabGAP-TBC PF00566.18 EPE30246.1 - 3.5e-31 108.6 4.5 1.5e-30 106.4 4.5 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF5102 PF17104.5 EPE30247.1 - 0.019 15.0 0.3 1.4 8.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) DAHP_synth_2 PF01474.16 EPE30249.1 - 1.3e-200 666.6 0.0 1.4e-200 666.4 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF723 PF05265.13 EPE30249.1 - 0.18 11.8 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF723) UBA_4 PF14555.6 EPE30250.1 - 0.028 14.2 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Aldolase_II PF00596.21 EPE30252.1 - 3.3e-44 151.1 0.0 3.8e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.18 EPE30253.1 - 5.3e-162 538.8 15.8 6.7e-162 538.5 15.8 1.1 1 0 0 1 1 1 1 Calreticulin family AHH PF14412.6 EPE30253.1 - 0.11 12.5 0.5 0.63 10.1 0.0 2.2 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH ApoLp-III PF07464.11 EPE30254.1 - 0.03 14.4 0.0 0.035 14.2 0.0 1.1 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) KxDL PF10241.9 EPE30254.1 - 0.032 14.5 0.1 0.044 14.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein Spc24 PF08286.11 EPE30254.1 - 0.058 13.6 0.2 0.069 13.4 0.2 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 EPE30254.1 - 0.088 12.2 0.2 0.09 12.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AhpC-TSA PF00578.21 EPE30255.1 - 5.3e-29 100.6 0.0 7.2e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EPE30255.1 - 1.6e-11 44.2 0.0 1.9e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EPE30255.1 - 7.7e-11 41.7 0.1 1.4e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MFS_1 PF07690.16 EPE30256.1 - 5.2e-38 130.9 28.7 5.2e-38 130.9 28.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE30256.1 - 8.5e-09 34.8 9.7 8.5e-09 34.8 9.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Transgly_assoc PF04226.13 EPE30256.1 - 0.03 14.6 4.5 0.03 14.6 1.7 2.5 2 0 0 2 2 2 0 Transglycosylase associated protein DUF3784 PF12650.7 EPE30256.1 - 0.034 14.3 0.1 0.034 14.3 0.1 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF3784) Myco_arth_vir_N PF09610.10 EPE30256.1 - 0.047 13.8 0.3 0.047 13.8 0.3 3.1 4 0 0 4 4 4 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DUF4191 PF13829.6 EPE30256.1 - 0.81 9.0 2.8 0.67 9.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Exo_endo_phos PF03372.23 EPE30258.1 - 4.5e-12 46.0 0.3 5.8e-12 45.6 0.3 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HpcH_HpaI PF03328.14 EPE30259.1 - 2.7e-43 147.7 0.0 4.7e-43 146.9 0.0 1.4 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EPE30259.1 - 1.3e-14 54.1 0.0 1.4e-06 27.7 0.0 2.1 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 EPE30259.1 - 0.021 13.7 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain DUF3860 PF12976.7 EPE30259.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) BolA PF01722.18 EPE30262.1 - 9.8e-28 96.3 2.4 1.2e-27 96.0 2.4 1.1 1 0 0 1 1 1 1 BolA-like protein Cofilin_ADF PF00241.20 EPE30262.1 - 0.023 14.5 0.0 0.033 14.0 0.0 1.3 1 1 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein RPA_C PF08784.11 EPE30262.1 - 0.026 15.2 0.1 0.034 14.8 0.1 1.2 1 0 0 1 1 1 0 Replication protein A C terminal Beta-lactamase PF00144.24 EPE30262.1 - 0.056 12.7 0.0 0.063 12.5 0.0 1.0 1 0 0 1 1 1 0 Beta-lactamase FAD_binding_3 PF01494.19 EPE30263.1 - 1.1e-13 51.1 6.1 1e-12 48.0 0.2 3.0 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE30263.1 - 6e-05 22.4 0.1 0.04 13.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EPE30263.1 - 8.2e-05 22.1 0.0 0.0002 20.8 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPE30263.1 - 0.00025 21.2 2.4 0.00031 20.9 0.8 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 EPE30263.1 - 0.00035 19.7 0.0 0.0076 15.3 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.6 EPE30263.1 - 0.00036 20.5 0.0 0.00099 19.1 0.0 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 EPE30263.1 - 0.00039 20.1 2.1 0.0096 15.5 0.6 2.6 1 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 EPE30263.1 - 0.0092 15.2 0.5 0.014 14.6 0.5 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EPE30263.1 - 0.016 15.7 0.9 0.24 12.0 0.7 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE30263.1 - 0.034 13.4 0.1 3.4 6.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 EPE30264.1 - 2.2e-23 82.8 22.2 2.2e-23 82.8 22.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 EPE30264.1 - 2.9 8.2 21.0 7 7.0 0.2 4.6 2 1 2 4 4 4 0 Domain of unknown function (DUF1772) SpoVAB PF13782.6 EPE30264.1 - 6.1 7.2 11.5 2.8 8.3 0.8 3.4 2 2 2 4 4 4 0 Stage V sporulation protein AB DUF2530 PF10745.9 EPE30264.1 - 7.6 6.9 7.7 1.3 9.3 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) Phenol_Hydrox PF02332.18 EPE30265.1 - 0.043 13.4 0.1 0.083 12.4 0.1 1.4 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase SKG6 PF08693.10 EPE30265.1 - 0.083 12.3 2.4 0.5 9.8 2.4 2.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TPR_1 PF00515.28 EPE30269.1 - 9.8e-09 34.7 1.3 0.08 12.8 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EPE30269.1 - 9.1e-08 31.7 1.5 0.0029 17.6 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat SET PF00856.28 EPE30269.1 - 1.8e-06 28.5 2.8 6.9e-06 26.6 1.0 2.5 2 1 0 2 2 2 1 SET domain TPR_16 PF13432.6 EPE30269.1 - 1.9e-06 28.4 0.6 0.0012 19.5 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EPE30269.1 - 6.2e-06 26.5 1.6 0.0002 21.8 0.6 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPE30269.1 - 0.00016 22.2 2.8 0.095 13.6 0.0 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EPE30269.1 - 0.00026 20.9 2.7 0.074 13.3 0.4 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE30269.1 - 0.00031 20.9 1.3 0.00067 19.8 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EPE30269.1 - 0.00034 20.2 0.2 0.034 13.8 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 EPE30269.1 - 0.012 15.7 0.8 0.082 13.1 0.4 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EPE30269.1 - 0.019 15.5 2.4 0.048 14.2 0.8 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EPE30269.1 - 0.074 13.1 0.4 6.7 6.9 0.1 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 EPE30269.1 - 0.083 13.6 0.2 0.37 11.5 0.2 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPE30269.1 - 0.39 11.0 4.0 5.2 7.4 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short_C2 PF13561.6 EPE30271.1 - 5.6e-56 189.7 0.1 7.3e-56 189.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE30271.1 - 1.4e-45 155.2 0.3 1.7e-45 154.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE30271.1 - 1.9e-14 54.0 0.4 2.5e-14 53.6 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE30271.1 - 0.00049 19.6 0.1 0.00086 18.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE30271.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Exo_endo_phos PF03372.23 EPE30272.1 - 0.017 14.7 0.1 0.038 13.5 0.1 1.8 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF2007 PF09413.10 EPE30273.1 - 0.13 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein AbiEii PF08843.11 EPE30274.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.4 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system Glyco_hydro_61 PF03443.14 EPE30275.1 - 9.4e-42 143.3 0.0 1.2e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase PF00069.25 EPE30277.1 - 1e-15 57.9 0.0 1.4e-15 57.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE30277.1 - 1.8e-05 24.2 0.0 3.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UQ_con PF00179.26 EPE30278.1 - 1.3e-26 92.9 0.0 2.5e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.6 EPE30278.1 - 5.2e-11 43.2 0.0 1.7e-10 41.5 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 EPE30278.1 - 1.7e-10 41.4 0.0 4.8e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain FAM199X PF15814.5 EPE30278.1 - 3.3 6.7 7.1 0.095 11.7 0.7 1.6 2 0 0 2 2 2 0 Protein family FAM199X Glyco_hydro_43 PF04616.14 EPE30279.1 - 4.2e-16 59.1 9.4 3.5e-13 49.5 3.9 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 zf-RING_4 PF14570.6 EPE30280.1 - 4.5e-05 23.2 6.8 0.0005 19.8 4.4 2.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 EPE30280.1 - 0.00029 20.8 6.1 0.00029 20.8 6.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EPE30280.1 - 0.00063 20.0 9.2 0.00068 19.9 5.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EPE30280.1 - 0.0014 18.6 6.0 0.0042 17.0 3.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EPE30280.1 - 0.0026 17.6 6.9 0.022 14.6 3.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE30280.1 - 0.017 15.0 4.4 0.017 15.0 4.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPE30280.1 - 0.11 12.7 8.2 0.94 9.7 5.1 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Cation_ATPase_C PF00689.21 EPE30281.1 - 0.049 13.4 9.3 0.42 10.3 3.6 2.5 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Fungal_trans_2 PF11951.8 EPE30282.1 - 9.2e-06 24.7 1.0 3.8e-05 22.7 1.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain AF-4 PF05110.13 EPE30282.1 - 0.013 13.6 0.8 0.017 13.2 0.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NAM-associated PF14303.6 EPE30282.1 - 0.26 12.0 3.2 11 6.8 2.3 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Hus1 PF04005.12 EPE30283.1 - 0.043 12.9 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Hus1-like protein Ank PF00023.30 EPE30285.1 - 5e-13 48.9 2.5 0.00032 21.0 0.1 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EPE30285.1 - 2.3e-11 43.7 3.3 6.5e-05 23.1 0.3 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPE30285.1 - 2e-10 41.0 1.4 1.8e-05 25.2 0.1 4.9 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE30285.1 - 1.8e-09 38.1 0.3 3.3e-06 27.6 0.1 2.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE30285.1 - 3.3e-09 36.2 0.6 0.0017 18.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat PQ-loop PF04193.14 EPE30287.1 - 6.5e-24 83.5 5.6 3.6e-14 52.3 2.7 2.7 2 0 0 2 2 2 2 PQ loop repeat Chromo PF00385.24 EPE30288.1 - 0.00092 19.1 2.7 0.0016 18.3 2.7 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain IHABP4_N PF16174.5 EPE30288.1 - 4.4 7.9 8.3 5.6 7.5 8.3 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal zf-RING_2 PF13639.6 EPE30290.1 - 3.4e-08 33.7 9.4 6.1e-08 32.9 9.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EPE30290.1 - 2.3e-07 30.7 5.1 4.4e-07 29.8 5.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EPE30290.1 - 3.3e-06 26.9 8.3 5.8e-06 26.1 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE30290.1 - 4.5e-06 26.5 8.5 7.6e-06 25.8 8.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EPE30290.1 - 7.5e-05 22.5 7.8 0.0017 18.1 7.6 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EPE30290.1 - 0.00016 21.5 7.1 0.00033 20.5 7.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EPE30290.1 - 0.00039 20.2 6.9 0.00075 19.2 6.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 EPE30290.1 - 0.0062 16.4 10.3 0.019 14.8 10.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPE30290.1 - 0.012 15.8 6.1 0.023 14.8 6.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FYVE PF01363.21 EPE30290.1 - 0.063 13.4 3.1 0.12 12.5 3.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-ANAPC11 PF12861.7 EPE30290.1 - 0.1 12.7 1.9 0.21 11.6 1.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-4CXXC_R1 PF10497.9 EPE30290.1 - 0.11 12.8 2.2 0.26 11.5 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-CHY PF05495.12 EPE30290.1 - 0.7 10.4 5.3 1.5 9.3 5.3 1.5 1 0 0 1 1 1 0 CHY zinc finger zf-C3HC4_5 PF17121.5 EPE30290.1 - 3 7.8 7.2 0.52 10.2 1.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Lipase_GDSL_2 PF13472.6 EPE30291.1 - 2.4e-11 44.4 0.2 3.2e-11 44.0 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE30291.1 - 7.1e-06 26.1 0.0 9.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Aminotran_1_2 PF00155.21 EPE30292.1 - 1e-44 153.2 0.0 1.4e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EPE30292.1 - 0.017 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Glyco_hydro_7 PF00840.20 EPE30293.1 - 8.7e-147 489.3 2.0 1.1e-146 489.0 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Kelch_1 PF01344.25 EPE30294.1 - 1.3e-30 104.7 19.9 4.2e-09 35.9 0.2 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.6 EPE30294.1 - 1.5e-24 85.4 15.8 2.2e-07 30.9 0.2 6.4 4 2 3 7 7 7 4 Kelch motif Kelch_4 PF13418.6 EPE30294.1 - 1.7e-17 63.1 17.4 0.0024 17.8 0.1 7.0 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EPE30294.1 - 4.9e-14 52.2 8.7 0.0014 18.8 0.2 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EPE30294.1 - 1.4e-11 43.9 16.3 0.0098 15.8 0.4 6.9 6 2 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 EPE30294.1 - 0.00024 21.0 7.9 4.5 7.4 0.0 5.3 5 1 0 5 5 5 2 Kelch motif DUF1668 PF07893.13 EPE30294.1 - 0.036 13.4 0.1 0.44 9.8 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1668) CBM_20 PF00686.19 EPE30294.1 - 0.11 12.5 0.1 0.81 9.6 0.0 2.5 3 0 0 3 3 3 0 Starch binding domain AAA_16 PF13191.6 EPE30296.1 - 2.5e-08 34.5 0.1 2.1e-07 31.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EPE30296.1 - 7.3e-08 32.5 0.0 1.9e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EPE30296.1 - 0.0013 19.0 0.0 0.0069 16.7 0.0 2.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EPE30296.1 - 0.0079 15.4 0.0 0.037 13.2 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.27 EPE30296.1 - 0.02 15.4 0.0 0.15 12.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 EPE30296.1 - 0.026 14.9 0.1 14 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EPE30296.1 - 0.032 14.0 0.0 0.14 11.9 0.0 2.1 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EPE30296.1 - 0.035 14.5 0.3 0.11 12.9 0.0 2.0 2 0 0 2 2 1 0 RNA helicase ATP_bind_1 PF03029.17 EPE30296.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EPE30296.1 - 0.088 12.5 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EPE30296.1 - 0.11 13.0 0.0 0.62 10.6 0.0 2.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EPE30296.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase UQ_con PF00179.26 EPE30297.1 - 3.9e-15 55.7 0.1 6.7e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EPE30297.1 - 0.0034 17.7 0.1 0.0078 16.5 0.1 1.6 1 0 0 1 1 1 1 RWD domain F-box-like PF12937.7 EPE30297.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 F-box-like Prok-E2_B PF14461.6 EPE30297.1 - 0.16 11.7 0.0 0.52 10.0 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic E2 family B FAD_binding_3 PF01494.19 EPE30298.1 - 5.2e-89 298.9 0.0 6.3e-89 298.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPE30298.1 - 3.2e-12 46.7 0.9 2.8e-10 40.3 0.9 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE30298.1 - 2e-05 24.0 0.1 6.4e-05 22.3 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE30298.1 - 0.0023 18.1 0.1 0.0075 16.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE30298.1 - 0.0034 16.5 0.1 0.1 11.7 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 EPE30298.1 - 0.0055 16.1 0.1 0.075 12.4 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EPE30298.1 - 0.036 14.6 0.0 5.2 7.7 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EPE30298.1 - 0.045 12.6 0.8 1 8.2 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.24 EPE30298.1 - 0.051 12.8 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EPE30298.1 - 0.19 10.9 0.2 0.49 9.6 0.2 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ost5 PF05251.12 EPE30298.1 - 1.6 9.1 5.0 0.22 11.8 0.9 1.7 2 0 0 2 2 1 0 Oligosaccharyltransferase subunit 5 zf-RING_2 PF13639.6 EPE30299.1 - 2.1e-05 24.8 6.4 2.1e-05 24.8 6.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EPE30299.1 - 0.0022 17.8 6.3 0.0022 17.8 6.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE30299.1 - 0.0036 17.2 5.4 0.0036 17.2 5.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Baculo_IE-1 PF05290.11 EPE30299.1 - 0.006 16.5 1.7 0.006 16.5 1.7 2.1 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 EPE30299.1 - 0.03 14.2 1.3 0.03 14.2 1.3 2.9 3 1 0 3 3 3 0 Prokaryotic RING finger family 4 zf-4CXXC_R1 PF10497.9 EPE30299.1 - 0.15 12.3 10.2 2.6 8.3 3.6 2.4 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_4 PF14570.6 EPE30299.1 - 0.64 9.9 10.2 0.49 10.2 6.9 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 EPE30299.1 - 0.99 9.3 14.1 0.047 13.5 4.4 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Mem_trans PF03547.18 EPE30300.1 - 3e-21 75.3 0.1 4.9e-21 74.6 0.1 1.4 1 1 0 1 1 1 1 Membrane transport protein adh_short PF00106.25 EPE30301.1 - 1.2e-13 50.9 0.0 2.9e-09 36.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE30301.1 - 0.00011 21.9 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE30301.1 - 0.00047 20.1 0.1 0.00075 19.4 0.1 1.3 1 0 0 1 1 1 1 KR domain GSDH PF07995.11 EPE30303.1 - 3e-117 391.7 0.1 3.5e-117 391.4 0.1 1.0 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 EPE30303.1 - 0.00054 19.9 0.0 0.063 13.4 0.0 3.3 3 0 0 3 3 3 1 NHL repeat Reg_prop PF07494.11 EPE30303.1 - 0.039 14.2 0.7 87 3.9 0.0 4.0 4 0 0 4 4 4 0 Two component regulator propeller TFIIA PF03153.13 EPE30304.1 - 0.00063 19.9 9.7 0.00067 19.8 9.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Bacteriocin_IIc PF10439.9 EPE30304.1 - 0.027 14.6 7.6 0.041 14.0 7.6 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.15 EPE30304.1 - 0.041 13.7 18.4 0.051 13.4 17.6 1.6 1 1 0 1 1 1 0 Glycine zipper 2TM domain Ndc1_Nup PF09531.10 EPE30304.1 - 0.23 10.1 5.1 0.28 9.8 5.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Gly-zipper_Omp PF13488.6 EPE30304.1 - 0.46 10.5 15.5 1 9.4 15.3 1.6 1 1 1 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.6 EPE30304.1 - 1.7 8.4 17.0 2.2 8.1 16.2 1.6 1 1 1 2 2 2 0 YMGG-like Gly-zipper HET PF06985.11 EPE30305.1 - 2.5e-36 125.2 0.7 5e-36 124.3 0.7 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ketoacyl-synt PF00109.26 EPE30306.1 - 1.8e-68 230.9 0.0 4.8e-68 229.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EPE30306.1 - 2.8e-64 216.4 0.0 8.5e-64 214.8 0.0 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EPE30306.1 - 4.4e-58 197.3 0.5 6.8e-58 196.7 0.5 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EPE30306.1 - 6.2e-54 183.2 0.0 1.1e-53 182.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EPE30306.1 - 2.9e-42 143.4 0.2 1.5e-41 141.1 0.1 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 EPE30306.1 - 5e-19 69.7 0.0 3.4e-18 67.0 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EPE30306.1 - 2e-17 63.3 0.0 2e-17 63.3 0.0 2.9 4 0 0 4 4 4 1 short chain dehydrogenase KAsynt_C_assoc PF16197.5 EPE30306.1 - 4.6e-17 62.5 0.0 1.5e-16 60.8 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 EPE30306.1 - 1e-12 48.1 0.5 5.8e-12 45.7 0.2 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 EPE30306.1 - 5.2e-11 42.5 0.1 1.3e-10 41.3 0.1 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 EPE30306.1 - 1.8e-09 37.8 0.1 3.9e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EPE30306.1 - 1.7e-05 24.7 0.4 5.9e-05 22.9 0.4 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Polysacc_synt_2 PF02719.15 EPE30306.1 - 0.0054 15.9 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Thiolase_N PF00108.23 EPE30306.1 - 0.0083 15.5 0.1 0.026 13.9 0.1 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain PALP PF00291.25 EPE30306.1 - 0.03 13.7 2.8 2.4 7.5 0.1 3.0 3 0 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme ACP_syn_III PF08545.10 EPE30306.1 - 0.1 12.4 0.7 0.96 9.3 0.7 2.4 1 1 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FSH1 PF03959.13 EPE30307.1 - 1.1e-24 87.3 0.0 2e-24 86.5 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF1993 PF09351.10 EPE30308.1 - 8.3e-54 182.1 0.3 9.3e-54 181.9 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) She2p PF11435.8 EPE30308.1 - 0.048 13.3 0.5 0.091 12.4 0.1 1.6 2 0 0 2 2 2 0 RNA binding protein She2p POX PF07526.11 EPE30308.1 - 0.082 13.5 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 Associated with HOX AAA_16 PF13191.6 EPE30309.1 - 4.9e-07 30.3 0.2 2.1e-06 28.3 0.0 2.2 3 0 0 3 3 3 1 AAA ATPase domain Ank_2 PF12796.7 EPE30309.1 - 5.2e-05 23.7 0.0 0.0026 18.3 0.0 2.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_22 PF13401.6 EPE30309.1 - 0.00059 20.1 1.2 0.01 16.1 0.1 3.4 2 1 2 4 4 4 1 AAA domain NACHT PF05729.12 EPE30309.1 - 0.0011 18.9 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Goodbye PF17109.5 EPE30309.1 - 0.0064 16.9 0.0 0.15 12.5 0.0 2.8 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain Ank_5 PF13857.6 EPE30309.1 - 0.057 13.8 0.0 5.6 7.4 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) AAA PF00004.29 EPE30309.1 - 0.14 12.6 0.1 1 9.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Meleagrin PF08189.11 EPE30309.1 - 0.18 11.6 0.8 0.38 10.5 0.8 1.5 1 0 0 1 1 1 0 Meleagrin/Cygnin family Peptidase_M10 PF00413.24 EPE30309.1 - 0.18 11.6 0.5 0.4 10.5 0.5 1.5 1 0 0 1 1 1 0 Matrixin Antimicrobial_1 PF08018.11 EPE30311.1 - 1.1 9.5 2.5 1.8 8.8 2.5 1.3 1 0 0 1 1 1 0 Frog antimicrobial peptide CSTF1_dimer PF16699.5 EPE30312.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain DUF5381 PF17353.2 EPE30312.1 - 8.2 6.2 8.3 0.74 9.6 2.2 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5381) VIT PF08487.10 EPE30314.1 - 9.4e-32 109.5 0.4 2.7e-31 108.1 0.1 2.0 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EPE30314.1 - 1e-28 100.2 0.0 2.8e-28 98.8 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 EPE30314.1 - 4.5e-13 48.9 0.0 1.2e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 EPE30314.1 - 4.4e-08 33.6 0.0 8.1e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EPE30314.1 - 8.2e-08 32.9 0.0 2.3e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain SRAP PF02586.14 EPE30314.1 - 0.029 13.9 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 SOS response associated peptidase (SRAP) TFIIA PF03153.13 EPE30314.1 - 7.8 6.4 17.3 14 5.5 17.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CtIP_N PF10482.9 EPE30315.1 - 5.3 7.1 11.4 0.079 13.0 0.9 2.8 2 1 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain CENP-H PF05837.12 EPE30315.1 - 6.2 7.3 22.8 2.4 8.6 1.9 3.3 2 1 1 3 3 3 0 Centromere protein H (CENP-H) YabA PF06156.13 EPE30315.1 - 8.3 7.1 11.1 28 5.4 2.9 3.3 1 1 2 3 3 3 0 Initiation control protein YabA Fib_alpha PF08702.10 EPE30315.1 - 8.4 6.6 9.6 2.5 8.3 0.9 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 EPE30315.1 - 9.3 5.5 17.9 3.6e+02 0.3 17.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Bac_rhamnosid6H PF17389.2 EPE30316.1 - 3.1e-16 59.6 0.0 1.7e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 EPE30316.1 - 3.2e-15 55.7 1.3 3.2e-15 55.7 1.3 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain GDE_C PF06202.14 EPE30316.1 - 0.00034 19.7 0.0 0.00063 18.8 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Glyco_hydro_36 PF17167.4 EPE30316.1 - 0.053 12.2 0.0 0.094 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Bac_rhamnosid PF05592.11 EPE30316.1 - 0.099 12.6 0.0 0.29 11.1 0.0 1.7 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Epimerase PF01370.21 EPE30317.1 - 1.9e-14 53.8 0.0 2.9e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE30317.1 - 7.3e-10 38.3 0.0 1.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EPE30317.1 - 2.3e-06 27.7 0.2 6.7e-06 26.1 0.2 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EPE30317.1 - 6.6e-06 25.5 0.1 9.7e-06 24.9 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EPE30317.1 - 1.3e-05 24.7 0.3 3.3e-05 23.5 0.1 1.7 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EPE30317.1 - 0.00039 20.1 0.3 0.00079 19.1 0.3 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EPE30317.1 - 0.0011 18.2 0.2 0.063 12.4 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 EPE30317.1 - 0.0016 18.0 0.4 0.067 12.6 0.3 2.5 2 1 0 2 2 2 1 short chain dehydrogenase PQ-loop PF04193.14 EPE30318.1 - 9e-20 70.2 3.0 1.1e-11 44.3 0.0 2.9 3 0 0 3 3 3 2 PQ loop repeat Cmc1 PF08583.10 EPE30318.1 - 0.037 14.1 1.9 0.072 13.1 1.9 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like adh_short PF00106.25 EPE30319.1 - 9e-29 100.3 0.2 1.1e-28 100.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE30319.1 - 1.2e-19 70.8 0.0 2.1e-19 70.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE30319.1 - 2.8e-09 37.1 0.2 4e-09 36.6 0.2 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE30319.1 - 0.0068 15.9 0.3 2.7 7.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EPE30319.1 - 0.014 14.6 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4905 PF16248.5 EPE30319.1 - 0.098 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4905) Shikimate_DH PF01488.20 EPE30319.1 - 0.17 12.0 0.2 0.27 11.3 0.2 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase IHHNV_capsid PF16530.5 EPE30320.1 - 0.098 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Infectious hypodermal and haematopoietic necrosis virus, capsid Aldose_epim PF01263.20 EPE30321.1 - 6.8e-39 134.0 0.0 8.4e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase FAM220 PF15487.6 EPE30323.1 - 0.25 11.0 1.8 0.38 10.3 1.8 1.2 1 0 0 1 1 1 0 FAM220 family Rif1_N PF12231.8 EPE30324.1 - 7.5e-127 423.4 1.3 1.2e-126 422.7 1.3 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.9 EPE30325.1 - 6.4e-127 424.4 0.7 7.5e-127 424.1 0.7 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn DUF3843 PF12954.7 EPE30325.1 - 0.074 12.0 0.1 0.29 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3843) Hepsin-SRCR PF09272.10 EPE30326.1 - 0.097 13.2 0.0 0.67 10.5 0.0 2.0 2 0 0 2 2 2 0 Hepsin, SRCR domain p450 PF00067.22 EPE30327.1 - 1.3e-41 142.8 0.0 2.2e-41 142.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF1129 PF06570.11 EPE30330.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Tannase PF07519.11 EPE30331.1 - 6.4e-81 272.6 0.0 8.4e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EPE30331.1 - 0.024 14.1 0.0 2 7.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Sugar_tr PF00083.24 EPE30333.1 - 9.7e-37 126.9 0.0 1.1e-36 126.7 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE30333.1 - 5.1e-12 45.4 0.1 5.6e-12 45.3 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 EPE30333.1 - 0.0044 16.1 0.0 0.0056 15.7 0.0 1.2 1 0 0 1 1 1 1 PUCC protein DUF5597 PF18120.1 EPE30334.1 - 2e-05 24.7 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_3 PF00933.21 EPE30335.1 - 2.5e-15 56.7 0.0 2.6e-15 56.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Zn_clus PF00172.18 EPE30336.1 - 6.2e-05 23.0 8.1 6.2e-05 23.0 8.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE30336.1 - 0.00012 21.2 0.4 0.00023 20.3 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 EPE30337.1 - 4.2e-21 75.3 0.0 5.8e-19 68.3 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE30337.1 - 3.9e-10 39.7 0.0 6.9e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE30337.1 - 9.2e-05 22.4 0.1 0.00015 21.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE30337.1 - 0.051 12.7 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 EPE30337.1 - 0.11 12.3 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase YuzL PF14115.6 EPE30338.1 - 0.022 15.2 2.7 0.022 15.2 2.7 1.6 2 0 0 2 2 2 0 YuzL-like protein HNH_2 PF13391.6 EPE30339.1 - 2.1e-09 37.4 0.1 8.8e-09 35.4 0.1 2.1 1 0 0 1 1 1 1 HNH endonuclease Adeno_Penton_B PF01686.17 EPE30339.1 - 0.03 12.8 0.0 0.043 12.3 0.0 1.1 1 0 0 1 1 1 0 Adenovirus penton base protein p450 PF00067.22 EPE30340.1 - 0.034 12.9 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 p450 PF00067.22 EPE30341.1 - 1e-74 252.0 0.0 1.2e-74 251.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ELO PF01151.18 EPE30342.1 - 7.3e-43 146.9 10.4 1.1e-22 80.8 1.4 2.1 1 1 1 2 2 2 2 GNS1/SUR4 family DUF4349 PF14257.6 EPE30343.1 - 0.13 11.7 4.0 0.13 11.7 2.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) AAA_23 PF13476.6 EPE30343.1 - 1.3 9.5 4.5 1.9 8.9 4.5 1.2 1 0 0 1 1 1 0 AAA domain zf-MYND PF01753.18 EPE30344.1 - 0.013 15.5 4.1 0.04 14.0 4.1 1.9 1 0 0 1 1 1 0 MYND finger zf-HIT PF04438.16 EPE30344.1 - 3.3 7.6 6.8 12 5.9 6.8 1.9 1 0 0 1 1 1 0 HIT zinc finger KH_1 PF00013.29 EPE30345.1 - 2e-48 162.1 12.6 2.3e-16 59.4 0.9 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EPE30345.1 - 1.8e-10 40.5 2.8 0.045 13.6 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EPE30345.1 - 3.1e-10 39.8 3.6 0.012 15.5 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EPE30345.1 - 0.00014 21.9 3.1 3.3 7.9 0.1 3.5 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 EPE30345.1 - 0.0083 16.1 0.1 5 7.2 0.0 3.1 3 0 0 3 3 3 1 KH-like RNA-binding domain TIP49 PF06068.13 EPE30346.1 - 9.5e-168 557.9 0.1 1.1e-167 557.6 0.1 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EPE30346.1 - 1.2e-22 79.8 0.0 2.9e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EPE30346.1 - 1.6e-11 44.8 0.3 7.2e-07 29.7 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EPE30346.1 - 3.4e-10 39.9 0.2 1.6e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EPE30346.1 - 3.7e-05 24.0 0.1 0.2 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EPE30346.1 - 0.00022 21.6 2.5 0.036 14.4 0.3 2.3 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EPE30346.1 - 0.00055 20.0 0.2 0.18 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EPE30346.1 - 0.00099 19.4 0.1 0.0025 18.1 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EPE30346.1 - 0.001 18.7 0.1 0.0029 17.2 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPE30346.1 - 0.0012 19.3 0.1 0.013 15.9 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 EPE30346.1 - 0.0016 18.2 0.1 1.7 8.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 EPE30346.1 - 0.0062 15.8 0.2 0.014 14.7 0.2 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 EPE30346.1 - 0.0072 16.9 0.0 0.072 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EPE30346.1 - 0.0093 15.4 0.2 0.45 9.9 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 EPE30346.1 - 0.016 14.5 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 EPE30346.1 - 0.031 13.6 0.3 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 KaiC DnaB_C PF03796.15 EPE30346.1 - 0.031 13.6 0.0 0.066 12.5 0.0 1.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 EPE30346.1 - 0.039 13.7 0.2 0.079 12.7 0.2 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 EPE30346.1 - 0.045 13.8 0.0 0.57 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 EPE30346.1 - 0.14 11.3 0.0 13 4.8 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase HMG_box PF00505.19 EPE30347.1 - 6.5e-22 77.7 0.8 1.2e-21 76.9 0.8 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EPE30347.1 - 2.2e-06 28.1 0.3 4.4e-06 27.2 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 EPE30347.1 - 0.075 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box AAA PF00004.29 EPE30348.1 - 2.9e-37 128.1 1.7 1.9e-35 122.1 0.0 3.4 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPE30348.1 - 1.1e-07 31.5 0.0 2.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EPE30348.1 - 0.0002 21.2 0.0 0.00067 19.4 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EPE30348.1 - 0.00024 21.5 0.1 0.0023 18.3 0.0 2.4 2 1 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.6 EPE30348.1 - 0.0022 18.2 0.0 0.018 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EPE30348.1 - 0.0037 17.2 0.6 9.4 6.1 0.0 3.7 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EPE30348.1 - 0.0056 16.9 0.1 0.07 13.4 0.0 2.6 2 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EPE30348.1 - 0.0093 15.7 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 EPE30348.1 - 0.011 15.7 0.0 0.031 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EPE30348.1 - 0.012 14.8 0.7 0.069 12.4 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain RNA_helicase PF00910.22 EPE30348.1 - 0.015 15.7 0.0 0.26 11.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 EPE30348.1 - 0.024 15.2 0.0 0.083 13.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EPE30348.1 - 0.04 13.3 0.1 0.084 12.2 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 EPE30348.1 - 0.068 13.3 0.0 5.9 7.0 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain Htr2 PF17909.1 EPE30348.1 - 0.16 12.2 1.4 0.56 10.5 1.4 1.9 1 0 0 1 1 1 0 Htr2 transmembrane domain AAA_30 PF13604.6 EPE30348.1 - 5.6 6.6 6.1 6.3 6.5 0.1 2.9 3 0 0 3 3 3 0 AAA domain Cu-oxidase_3 PF07732.15 EPE30349.1 - 2.8e-40 137.0 8.3 4e-40 136.5 2.4 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EPE30349.1 - 2e-39 134.4 4.1 7.2e-38 129.4 0.2 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EPE30349.1 - 6.3e-39 133.7 0.2 2.8e-38 131.5 0.2 2.0 2 0 0 2 2 2 1 Multicopper oxidase Fungal_lectin_2 PF18647.1 EPE30350.1 - 0.012 16.1 0.1 0.022 15.2 0.1 1.5 1 0 0 1 1 1 0 Alpha-galactosyl-binding fungal lectin Glyco_hydro_114 PF03537.13 EPE30352.1 - 5.7e-79 264.7 0.0 7.3e-79 264.3 0.0 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 CBM_1 PF00734.18 EPE30352.1 - 2.4e-07 30.6 18.7 5e-07 29.6 14.4 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF5333 PF17267.2 EPE30352.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5333) PTH2 PF01981.16 EPE30353.1 - 1.4e-46 157.6 0.5 1.9e-46 157.2 0.5 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 RIBIOP_C PF04950.12 EPE30354.1 - 6.8e-112 373.7 0.0 1.1e-111 372.9 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EPE30354.1 - 7.1e-17 61.3 0.0 2.5e-16 59.5 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain BING4CT PF08149.11 EPE30355.1 - 7.8e-39 131.4 0.0 8.8e-36 121.6 0.0 3.3 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 EPE30355.1 - 1.9e-07 31.3 0.1 2.8 8.3 0.0 6.1 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPE30355.1 - 0.0027 18.5 0.0 0.43 11.5 0.0 3.7 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EPE30355.1 - 0.042 12.9 0.1 0.087 11.9 0.0 1.6 2 0 0 2 2 2 0 Coatomer WD associated region SET PF00856.28 EPE30356.1 - 2.6e-08 34.4 0.3 3.6e-07 30.7 0.3 2.4 1 1 0 1 1 1 1 SET domain MFS_1 PF07690.16 EPE30357.1 - 3.6e-17 62.3 43.9 1.5e-16 60.3 38.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE30357.1 - 5e-05 22.4 6.9 5e-05 22.4 6.9 2.9 2 2 1 3 3 3 1 Sugar (and other) transporter cobW PF02492.19 EPE30358.1 - 8.8e-35 119.9 0.0 1.2e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EPE30358.1 - 3.9e-05 22.8 1.1 0.00037 19.6 1.1 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 EPE30358.1 - 0.0024 18.4 0.0 0.0033 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EPE30358.1 - 0.0048 17.0 0.0 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ResIII PF04851.15 EPE30358.1 - 0.077 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EPE30358.1 - 0.13 12.6 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 EPE30358.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 EPE30358.1 - 0.18 11.7 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain SNAP PF14938.6 EPE30359.1 - 3.1e-28 99.0 18.4 4.1e-15 56.0 4.0 2.2 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EPE30359.1 - 0.0066 16.7 14.0 0.034 14.4 1.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPE30359.1 - 0.032 14.9 0.9 0.032 14.9 0.9 4.6 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EPE30359.1 - 0.27 11.4 9.1 13 6.1 0.0 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPE30359.1 - 1.4 10.0 19.5 6.1 7.9 0.1 5.8 4 3 3 7 7 7 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 EPE30359.1 - 5.5 6.0 7.6 0.2 10.8 0.6 2.2 3 0 0 3 3 3 0 Spatacsin C-terminus Glu-tRNAGln PF02686.15 EPE30360.1 - 9.1e-06 25.9 1.0 1.8e-05 24.9 1.0 1.7 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF726 PF05277.12 EPE30361.1 - 4.3e-131 436.9 1.3 5.8e-131 436.5 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 EPE30361.1 - 0.015 15.5 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain RTT107_BRCT_6 PF16771.5 EPE30361.1 - 0.1 12.7 1.0 0.26 11.5 1.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain PE-PPE PF08237.11 EPE30361.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_6 PF12697.7 EPE30361.1 - 0.49 11.0 1.7 1.2 9.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_U49 PF10463.9 EPE30362.1 - 0.15 11.8 0.1 0.18 11.6 0.1 1.1 1 0 0 1 1 1 0 Peptidase U49 Mus7 PF09462.10 EPE30363.1 - 8.6e-89 299.0 0.2 1.4e-88 298.3 0.2 1.4 1 0 0 1 1 1 1 Mus7/MMS22 family SurA_N_3 PF13624.6 EPE30363.1 - 0.084 12.7 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 SurA N-terminal domain HET PF06985.11 EPE30364.1 - 7.8e-24 84.7 0.0 1.6e-23 83.7 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GFRP PF06399.13 EPE30365.1 - 0.096 12.6 0.5 9.2 6.2 0.0 2.4 1 1 1 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Lactamase_B_2 PF12706.7 EPE30366.1 - 1.2e-14 54.3 0.0 2.3e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EPE30366.1 - 9.9e-13 48.3 0.2 1.4e-11 44.6 0.2 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EPE30366.1 - 0.024 14.6 4.6 0.13 12.3 3.1 2.5 2 1 1 3 3 3 0 Metallo-beta-lactamase superfamily Kdo PF06293.14 EPE30368.1 - 3e-10 39.8 0.0 4.8e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EPE30368.1 - 5.7e-09 35.7 0.0 8.1e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EPE30368.1 - 6.1e-09 36.1 0.7 0.00031 20.7 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EPE30368.1 - 0.0003 20.1 0.0 0.00046 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EPE30368.1 - 0.00099 18.8 0.0 0.0023 17.6 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 EPE30368.1 - 0.063 12.0 0.0 0.086 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase EcKinase PF02958.20 EPE30368.1 - 0.11 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Aldo_ket_red PF00248.21 EPE30369.1 - 5.7e-08 32.3 0.0 7.8e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.20 EPE30370.1 - 1.6e-47 161.0 4.2 1.1e-45 155.0 4.2 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 EPE30370.1 - 0.059 14.1 0.2 0.11 13.2 0.2 1.6 1 1 0 1 1 1 0 Pullulanase N1-terminal domain Maf1 PF09174.10 EPE30371.1 - 1.8e-61 207.3 0.0 2.4e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator polyprenyl_synt PF00348.17 EPE30373.1 - 5.8e-67 225.4 0.0 7e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CDC14 PF08045.11 EPE30374.1 - 5.6e-124 412.9 0.0 6.6e-124 412.6 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component SKG6 PF08693.10 EPE30375.1 - 0.014 14.8 0.2 0.027 13.9 0.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Mid2 PF04478.12 EPE30375.1 - 0.032 14.1 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MCM PF00493.23 EPE30377.1 - 1.5e-99 331.7 0.0 2.3e-99 331.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EPE30377.1 - 3.8e-39 133.4 0.1 6.9e-39 132.6 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EPE30377.1 - 1.7e-34 119.3 40.0 1.7e-34 119.3 40.0 2.3 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EPE30377.1 - 2.9e-25 88.5 0.4 8.7e-25 87.0 0.4 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EPE30377.1 - 2.6e-14 53.7 0.1 6.7e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EPE30377.1 - 3e-08 33.3 0.2 5.3e-06 26.0 0.0 2.8 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EPE30377.1 - 5.5e-06 26.4 0.0 1.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EPE30377.1 - 0.00072 19.4 0.0 0.0094 15.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EPE30377.1 - 0.0042 16.8 0.1 0.019 14.7 0.1 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF3113 PF11310.8 EPE30377.1 - 0.034 14.1 1.9 0.046 13.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) zf-UBR PF02207.20 EPE30378.1 - 2.3e-14 53.3 4.2 2.3e-14 53.3 4.2 3.3 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Glyco_hydro_3_C PF01915.22 EPE30379.1 - 1.2e-61 208.3 0.0 2.5e-61 207.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE30379.1 - 1.1e-46 159.8 0.0 1.7e-46 159.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE30379.1 - 6.6e-24 83.8 0.8 1.5e-23 82.7 0.8 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EPE30379.1 - 1.1e-13 51.2 0.0 2.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Macro_2 PF14519.6 EPE30379.1 - 0.0087 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Macro-like domain Lipase_GDSL_2 PF13472.6 EPE30379.1 - 0.053 13.9 0.0 0.096 13.1 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Diphtheria_C PF02763.14 EPE30379.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Diphtheria toxin, C domain IDO PF01231.18 EPE30380.1 - 2e-37 129.0 0.0 2.5e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase CAP PF00188.26 EPE30381.1 - 5.8e-20 72.4 1.5 1.8e-19 70.8 1.5 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Cu-oxidase_3 PF07732.15 EPE30382.1 - 1.4e-43 147.6 2.3 2.5e-43 146.8 0.8 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EPE30382.1 - 2.9e-41 140.4 5.9 6.8e-39 132.7 0.3 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EPE30382.1 - 4e-34 118.0 0.4 2.3e-32 112.3 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase Aldo_ket_red PF00248.21 EPE30383.1 - 1.1e-56 192.2 0.0 1.3e-56 192.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Syntaxin PF00804.25 EPE30384.1 - 3e-22 79.3 10.3 3e-22 79.3 10.3 1.8 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 EPE30384.1 - 1.1e-10 41.3 0.8 2.2e-10 40.4 0.1 1.9 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 EPE30384.1 - 0.0035 17.1 11.9 0.018 14.8 11.9 1.9 1 1 0 1 1 1 1 Membrane fusion protein Use1 ETRAMP PF09716.10 EPE30384.1 - 0.0042 17.1 0.0 0.0084 16.2 0.0 1.7 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) PBP1_TM PF14812.6 EPE30384.1 - 0.032 14.6 0.1 0.032 14.6 0.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2207 PF09972.9 EPE30384.1 - 0.16 10.7 1.6 0.87 8.3 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Allexi_40kDa PF05549.11 EPE30384.1 - 0.16 11.4 7.1 0.089 12.3 2.5 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein Bacillus_PapR PF05968.11 EPE30384.1 - 0.2 11.5 1.8 0.5 10.3 0.0 2.5 3 0 0 3 3 3 0 Bacillus PapR protein MCU PF04678.13 EPE30384.1 - 0.59 10.2 8.9 5 7.2 8.9 2.3 1 1 0 1 1 1 0 Mitochondrial calcium uniporter SurA_N_3 PF13624.6 EPE30384.1 - 2.9 7.7 13.9 8.4 6.2 0.2 2.4 2 0 0 2 2 2 0 SurA N-terminal domain Duffy_binding PF05424.11 EPE30384.1 - 4.4 7.3 9.0 33 4.5 9.0 2.2 1 1 0 1 1 1 0 Duffy binding domain COPIIcoated_ERV PF07970.12 EPE30385.1 - 3e-38 131.9 0.1 4.2e-38 131.4 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EPE30385.1 - 3.2e-24 85.1 0.0 6.5e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1996 PF09362.10 EPE30386.1 - 1.2e-83 280.7 1.4 1.6e-83 280.3 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 EPE30386.1 - 2.2e-05 24.5 5.8 3.1e-05 24.1 0.0 2.8 3 0 0 3 3 3 1 WSC domain PhoD PF09423.10 EPE30387.1 - 4e-117 391.1 1.8 5e-117 390.8 1.8 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EPE30387.1 - 8.8e-34 115.9 0.1 2e-33 114.8 0.1 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EPE30387.1 - 4.3e-05 24.0 3.2 4.5e-05 23.9 1.2 2.2 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain SRTM1 PF15872.5 EPE30388.1 - 0.011 15.9 0.9 0.013 15.7 0.9 1.0 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 PspB PF06667.12 EPE30388.1 - 0.027 14.5 0.2 0.029 14.4 0.2 1.2 1 0 0 1 1 1 0 Phage shock protein B DUF3328 PF11807.8 EPE30388.1 - 0.032 14.0 0.0 0.035 13.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF5412 PF17428.2 EPE30388.1 - 0.037 13.9 0.3 0.039 13.8 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5412) TRP PF06011.12 EPE30388.1 - 0.043 12.5 0.6 0.048 12.4 0.6 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF390 PF04094.14 EPE30388.1 - 0.071 11.4 0.0 0.086 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) SARAF PF06682.12 EPE30388.1 - 0.19 11.4 0.0 0.2 11.3 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Syndecan PF01034.20 EPE30388.1 - 0.36 10.8 4.3 0.59 10.1 4.3 1.2 1 0 0 1 1 1 0 Syndecan domain Sigma_reg_N PF13800.6 EPE30388.1 - 0.56 10.5 5.0 0.68 10.3 4.5 1.4 1 1 0 1 1 1 0 Sigma factor regulator N-terminal DUF1201 PF06716.11 EPE30388.1 - 1 9.4 5.2 2 8.5 5.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1201) MFS_1 PF07690.16 EPE30389.1 - 2.1e-30 105.8 42.4 1.5e-29 103.0 39.5 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE30389.1 - 4.6e-08 32.4 10.3 4.6e-08 32.4 10.3 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EPE30389.1 - 6.7e-07 28.1 9.3 6.7e-07 28.1 9.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF43 PF01861.16 EPE30389.1 - 0.003 16.8 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Iron_permease PF04120.12 EPE30389.1 - 0.11 12.3 0.1 0.11 12.3 0.1 3.1 2 1 1 3 3 3 0 Low affinity iron permease p450 PF00067.22 EPE30390.1 - 4e-49 167.6 0.0 5.2e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 EPE30391.1 - 0.00059 19.9 9.9 0.0011 19.0 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 EPE30392.1 - 1.3e-31 109.8 2.8 2.3e-31 109.1 2.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EPE30392.1 - 1.4e-20 73.2 0.0 3.7e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 EPE30392.1 - 3.6e-16 59.1 0.3 7.1e-16 58.2 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EPE30392.1 - 1e-11 45.5 0.1 2.2e-11 44.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EPE30392.1 - 1.5e-05 25.2 0.1 2.8e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain A_deaminase PF00962.22 EPE30393.1 - 3.8e-28 98.8 0.0 6.1e-28 98.1 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase ATG2_CAD PF13329.6 EPE30394.1 - 8.2e-44 149.1 0.0 2.2e-43 147.6 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 EPE30394.1 - 5.8e-22 77.9 0.3 1.8e-21 76.3 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 EPE30394.1 - 2.5e-09 37.2 0.1 9.6e-09 35.4 0.1 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ubiquitin PF00240.23 EPE30395.1 - 4e-15 55.3 0.0 1e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family zf-AN1 PF01428.16 EPE30395.1 - 6.9e-12 45.3 4.3 6.9e-12 45.3 4.3 1.7 1 1 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.8 EPE30395.1 - 4.2e-08 32.9 0.0 6.2e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EPE30395.1 - 0.0025 18.4 0.0 0.0029 18.1 0.0 1.3 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EPE30395.1 - 0.09 12.6 0.3 0.14 12.0 0.3 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Transp_Tc5_C PF04236.15 EPE30395.1 - 0.15 12.4 2.6 0.35 11.2 2.6 1.6 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain ADH_N PF08240.12 EPE30396.1 - 1.9e-25 88.9 1.7 1.9e-25 88.9 1.7 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE30396.1 - 1.2e-19 70.6 0.2 2.2e-19 69.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPE30396.1 - 0.0011 18.3 0.9 0.002 17.5 0.9 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 EPE30396.1 - 0.0081 16.4 0.1 0.014 15.6 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N_2 PF13602.6 EPE30396.1 - 0.015 16.4 0.0 0.039 15.0 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 EPE30396.1 - 0.041 14.1 0.1 0.082 13.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 EPE30396.1 - 0.13 11.7 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.7 EPE30397.1 - 3.2e-13 50.8 0.0 3.8e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PrsW-protease PF13367.6 EPE30397.1 - 0.046 13.2 0.1 0.067 12.6 0.1 1.2 1 0 0 1 1 1 0 PrsW family intramembrane metalloprotease Ser_hydrolase PF06821.13 EPE30397.1 - 0.062 13.1 0.1 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 Serine hydrolase CMD PF02627.20 EPE30398.1 - 5.7e-09 35.9 0.0 7.5e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family GNVR PF13807.6 EPE30398.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase ATP-synt_C PF00137.21 EPE30399.1 - 4.3e-35 119.9 33.9 6.8e-22 77.6 14.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Ribosomal_L7Ae PF01248.26 EPE30400.1 - 5.2e-24 83.8 0.1 6e-24 83.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EPE30400.1 - 0.00043 20.4 0.0 0.0006 19.9 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EPE30400.1 - 0.0011 18.8 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Methyltransf_34 PF11312.8 EPE30401.1 - 3e-112 374.8 0.0 3.5e-112 374.6 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase HATPase_c PF02518.26 EPE30403.1 - 1.2e-25 90.2 0.1 5.9e-24 84.7 0.1 2.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPE30403.1 - 6.3e-25 87.5 0.2 1.3e-24 86.5 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPE30403.1 - 2.8e-14 52.9 0.0 5.6e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EPE30403.1 - 0.0015 18.9 0.6 1.1 9.6 0.3 2.5 2 0 0 2 2 2 2 HAMP domain Chorion_1 PF01723.16 EPE30403.1 - 0.063 13.2 0.2 0.17 11.9 0.2 1.6 1 0 0 1 1 1 0 Chorion protein Syja_N PF02383.18 EPE30404.1 - 2.7e-93 312.8 0.0 4.8e-93 312.0 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EPE30404.1 - 8.3e-43 144.8 0.0 1.5e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase CEND1 PF15677.5 EPE30404.1 - 9 6.8 7.4 37 4.8 6.5 2.2 1 1 1 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 bZIP_1 PF00170.21 EPE30406.1 - 5.9e-10 39.1 6.0 5.9e-10 39.1 6.0 1.6 2 0 0 2 2 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPE30406.1 - 0.00032 20.7 7.4 0.00032 20.7 7.4 2.8 2 1 1 3 3 3 1 Basic region leucine zipper ATG16 PF08614.11 EPE30406.1 - 0.007 16.6 5.0 0.01 16.1 5.0 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) GAS PF13851.6 EPE30406.1 - 0.013 14.9 4.4 0.017 14.5 4.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 EPE30406.1 - 0.034 14.3 4.8 0.045 13.9 4.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HALZ PF02183.18 EPE30406.1 - 0.045 14.0 1.9 0.074 13.3 1.5 1.6 1 1 0 1 1 1 0 Homeobox associated leucine zipper DUF4472 PF14739.6 EPE30406.1 - 0.072 13.8 2.7 0.12 13.1 2.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) V_ATPase_I PF01496.19 EPE30406.1 - 0.079 10.9 2.3 0.095 10.6 2.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 EPE30406.1 - 0.16 12.7 2.1 0.22 12.2 1.7 1.4 1 1 0 1 1 1 0 Initiation control protein YabA TMF_DNA_bd PF12329.8 EPE30406.1 - 0.2 11.7 3.0 0.18 11.8 1.4 1.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding HAUS-augmin3 PF14932.6 EPE30406.1 - 0.35 10.4 5.3 0.46 10.0 5.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Zwint PF15556.6 EPE30406.1 - 0.62 9.5 5.5 0.81 9.1 5.5 1.1 1 0 0 1 1 1 0 ZW10 interactor bZIP_Maf PF03131.17 EPE30406.1 - 1.9 9.0 16.5 6 7.5 16.2 1.9 1 1 1 2 2 2 0 bZIP Maf transcription factor Transketolase_N PF00456.21 EPE30407.1 - 1.3e-152 507.6 0.2 1.8e-152 507.1 0.2 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EPE30407.1 - 3e-46 157.3 0.0 4.3e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EPE30407.1 - 4.5e-11 42.7 0.0 9.8e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EPE30407.1 - 4.2e-05 22.9 0.1 6.5e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.21 EPE30407.1 - 0.018 14.3 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase DUF5308 PF17233.2 EPE30408.1 - 4.2e-45 153.9 8.6 7.5e-45 153.1 8.6 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5308) Filament PF00038.21 EPE30409.1 - 0.0006 19.5 32.8 0.0006 19.5 32.8 4.2 2 1 1 4 4 4 2 Intermediate filament protein ATG16 PF08614.11 EPE30409.1 - 0.0029 17.8 74.6 0.1 12.8 11.5 5.3 2 1 3 5 5 5 4 Autophagy protein 16 (ATG16) XRCC4 PF06632.12 EPE30409.1 - 0.0098 14.8 0.1 0.0098 14.8 0.1 4.2 2 2 2 4 4 4 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 CCDC92 PF14916.6 EPE30409.1 - 0.76 9.6 0.0 0.76 9.6 0.0 3.9 4 1 0 4 4 4 0 Coiled-coil domain of unknown function zf-C2H2 PF00096.26 EPE30410.1 - 0.00016 22.0 13.7 0.11 13.0 2.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE30410.1 - 0.86 10.6 12.5 22 6.2 1.6 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger MFS_1 PF07690.16 EPE30411.1 - 2.5e-30 105.6 38.7 2.5e-30 105.6 38.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily NTP_transf_9 PF04248.12 EPE30412.1 - 9.7e-38 128.0 1.4 1.5e-29 101.7 0.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF427) HBS1_N PF08938.10 EPE30412.1 - 0.19 12.1 0.1 0.44 10.9 0.1 1.6 1 0 0 1 1 1 0 HBS1 N-terminus 6PGD PF00393.19 EPE30413.1 - 4.1e-93 311.9 0.3 5e-93 311.6 0.3 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EPE30413.1 - 7.1e-35 120.5 0.0 1.7e-34 119.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EPE30413.1 - 1.1e-05 25.4 0.1 2.7e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EPE30413.1 - 7.5e-05 23.2 0.0 0.00023 21.7 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 EPE30413.1 - 0.00081 19.0 0.4 0.033 13.7 0.1 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EPE30413.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EPE30413.1 - 0.018 14.7 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 EPE30413.1 - 0.026 14.8 0.0 0.17 12.1 0.0 2.2 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_11 PF14833.6 EPE30413.1 - 0.033 14.4 0.0 0.09 13.0 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 EPE30413.1 - 0.17 11.9 0.0 0.47 10.5 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SET PF00856.28 EPE30414.1 - 0.013 15.9 0.1 0.03 14.7 0.0 1.7 2 0 0 2 2 2 0 SET domain AMP-binding PF00501.28 EPE30416.1 - 3.5e-69 233.4 0.0 5.9e-69 232.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EPE30416.1 - 1.5e-67 227.5 0.0 2.1e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EPE30416.1 - 3.3e-10 39.5 0.0 9.6e-10 37.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPE30416.1 - 7.1e-10 38.7 0.0 1.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EPE30416.1 - 4.5e-07 30.1 0.0 9.9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPE30416.1 - 0.00027 21.9 0.0 0.0041 18.1 0.0 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 EPE30416.1 - 0.0059 16.1 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EPE30416.1 - 0.0088 15.9 0.0 3.2 7.6 0.0 2.9 2 0 0 2 2 2 2 NAD(P)H-binding Glyco_hydro_15 PF00723.21 EPE30417.1 - 4.8e-106 355.2 0.1 5.8e-106 354.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EPE30417.1 - 4.4e-34 116.3 0.1 1.1e-33 115.0 0.1 1.7 1 0 0 1 1 1 1 Starch binding domain SART-1 PF03343.13 EPE30418.1 - 1.4e-194 648.2 67.5 1.6e-194 648.0 67.5 1.0 1 0 0 1 1 1 1 SART-1 family HeLo PF14479.6 EPE30419.1 - 4.6e-28 98.5 0.0 2.3e-27 96.2 0.0 2.0 1 1 0 1 1 1 1 Prion-inhibition and propagation F-box PF00646.33 EPE30420.1 - 0.089 12.7 1.3 12 5.9 0.2 2.6 2 0 0 2 2 2 0 F-box domain DUF4010 PF13194.6 EPE30421.1 - 0.16 11.6 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Shisa PF13908.6 EPE30421.1 - 0.68 10.2 0.0 0.68 10.2 0.0 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF676 PF05057.14 EPE30423.1 - 3e-55 187.1 0.0 4.4e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EPE30423.1 - 0.00027 20.8 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 EPE30423.1 - 0.00098 19.0 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EPE30423.1 - 0.0011 19.6 0.0 0.0081 16.8 0.0 2.1 1 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EPE30423.1 - 0.006 16.3 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein DLH PF01738.18 EPE30423.1 - 0.12 11.9 0.0 0.35 10.4 0.0 1.8 2 1 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EPE30423.1 - 0.19 11.5 0.3 18 5.0 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF915 PF06028.11 EPE30423.1 - 0.2 10.9 0.5 6.2 6.1 0.0 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) CHORD PF04968.12 EPE30424.1 - 0.002 18.8 5.7 0.008 16.9 0.7 2.5 1 1 1 2 2 2 2 CHORD BTK PF00779.19 EPE30424.1 - 0.21 11.4 2.8 0.49 10.2 2.8 1.6 1 0 0 1 1 1 0 BTK motif DNA_pol3_delta2 PF13177.6 EPE30425.1 - 1.9e-11 44.0 0.0 3.7e-11 43.1 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EPE30425.1 - 1.6e-06 28.5 0.2 3.7e-06 27.4 0.2 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EPE30425.1 - 4.2e-05 23.6 0.0 0.00011 22.2 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 EPE30425.1 - 7.7e-05 23.0 0.3 0.00057 20.2 0.2 2.3 1 1 2 3 3 3 1 AAA domain AAA_16 PF13191.6 EPE30425.1 - 0.0011 19.3 0.6 0.011 16.1 0.3 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EPE30425.1 - 0.0016 18.2 0.5 0.0047 16.7 0.5 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EPE30425.1 - 0.012 16.2 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Rep_fac_C PF08542.11 EPE30425.1 - 0.029 14.8 0.0 0.16 12.4 0.0 2.2 2 0 0 2 2 2 0 Replication factor C C-terminal domain T4SS-DNA_transf PF02534.14 EPE30425.1 - 0.052 12.3 0.1 0.12 11.1 0.0 1.5 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer AAA_5 PF07728.14 EPE30425.1 - 0.19 11.7 0.5 0.76 9.8 0.5 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AATase PF07247.12 EPE30426.1 - 1.4e-09 37.1 0.0 0.00027 19.6 0.0 2.7 1 1 1 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.20 EPE30426.1 - 0.00023 20.0 0.0 0.023 13.4 0.2 2.8 3 1 0 3 3 3 2 Condensation domain HTH_42 PF06224.12 EPE30427.1 - 0.0035 16.9 1.0 0.0042 16.7 1.0 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain COG2 PF06148.11 EPE30427.1 - 0.18 11.9 2.6 0.26 11.4 2.6 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Putative_PNPOx PF01243.20 EPE30430.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase VWA_2 PF13519.6 EPE30431.1 - 4.4e-12 46.6 0.1 3.3e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 EPE30431.1 - 2.1e-10 41.1 0.0 3.8e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EPE30431.1 - 0.013 14.9 0.6 0.038 13.4 0.6 1.7 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein Ndc1_Nup PF09531.10 EPE30434.1 - 0.09 11.5 2.3 0.082 11.6 2.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CD99L2 PF12301.8 EPE30435.1 - 0.012 15.9 0.4 0.012 15.9 0.4 3.3 3 1 0 3 3 3 0 CD99 antigen like protein 2 Ish1 PF10281.9 EPE30435.1 - 0.17 12.2 0.3 0.74 10.2 0.0 2.3 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein BSP_II PF05432.11 EPE30435.1 - 1.4 8.5 9.5 5.1 6.7 9.5 1.9 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Trans_reg_C PF00486.28 EPE30437.1 - 0.061 13.4 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal OTT_1508_deam PF14441.6 EPE30438.1 - 5.8e-16 58.3 2.6 5.8e-16 58.3 2.6 3.0 2 1 0 2 2 2 1 OTT_1508-like deaminase zf-MYND PF01753.18 EPE30438.1 - 4e-06 26.8 15.0 9.4e-06 25.6 15.0 1.7 1 0 0 1 1 1 1 MYND finger ACCA PF03255.14 EPE30438.1 - 0.0039 17.1 2.1 0.036 13.9 0.1 3.3 4 0 0 4 4 4 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Sigma70_ner PF04546.13 EPE30438.1 - 0.078 12.9 3.0 0.18 11.7 3.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-C6H2 PF15801.5 EPE30438.1 - 2.1 8.7 11.3 7.7 6.9 11.3 2.0 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-CCHC PF00098.23 EPE30439.1 - 0.02 14.9 5.3 0.02 14.9 5.3 4.8 5 0 0 5 5 5 0 Zinc knuckle DUF5127 PF17168.4 EPE30439.1 - 0.08 12.7 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5127) ORMDL PF04061.14 EPE30440.1 - 4.9e-59 198.0 3.5 5.6e-59 197.8 3.5 1.0 1 0 0 1 1 1 1 ORMDL family MFS_1 PF07690.16 EPE30441.1 - 3.3e-37 128.2 40.0 3.3e-37 128.2 40.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE30441.1 - 1.4e-09 37.4 10.9 1.4e-09 37.4 10.9 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter PAP2_C PF14360.6 EPE30441.1 - 0.048 14.2 5.4 0.069 13.7 0.4 3.3 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Ank_2 PF12796.7 EPE30442.1 - 8.1e-17 61.6 0.3 7.5e-11 42.5 0.1 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE30442.1 - 3.1e-13 49.9 0.9 1.8e-05 25.2 0.3 5.4 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE30442.1 - 6.3e-12 44.6 1.7 0.013 16.0 0.1 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EPE30442.1 - 2e-06 28.0 1.4 0.095 13.1 0.0 4.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EPE30442.1 - 2.2e-06 27.8 4.5 0.0067 16.8 0.2 5.0 5 0 0 5 5 5 1 Ankyrin repeat F-box-like PF12937.7 EPE30442.1 - 0.031 14.2 0.3 0.061 13.2 0.3 1.6 1 0 0 1 1 1 0 F-box-like RTA1 PF04479.13 EPE30443.1 - 7.4e-50 169.4 9.7 7.4e-50 169.4 9.7 1.4 2 0 0 2 2 2 1 RTA1 like protein Caveolin PF01146.17 EPE30443.1 - 0.0081 16.1 1.6 0.034 14.1 1.6 2.1 1 0 0 1 1 1 1 Caveolin Vps39_1 PF10366.9 EPE30444.1 - 3.5e-33 114.1 0.0 2.9e-32 111.2 0.0 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 EPE30444.1 - 1.6e-30 105.7 0.0 6.8e-30 103.7 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 EPE30444.1 - 1.5e-17 64.1 0.0 1.3e-16 61.0 0.0 2.1 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 EPE30444.1 - 5.1e-05 23.2 3.2 8.9e-05 22.4 0.8 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS CHASE6_C PF17150.4 EPE30444.1 - 0.093 13.4 0.0 0.34 11.6 0.0 2.0 1 0 0 1 1 1 0 C-terminal domain of two-partite extracellular sensor domain Gon7 PF08738.10 EPE30445.1 - 3.5e-11 43.2 4.1 3.5e-11 43.2 4.1 1.7 1 1 1 2 2 2 1 Gon7 family HbrB PF08539.11 EPE30446.1 - 1.2e-52 178.3 1.2 2.2e-52 177.4 0.0 2.0 2 0 0 2 2 2 1 HbrB-like TMEM51 PF15345.6 EPE30447.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Mid2 PF04478.12 EPE30447.1 - 0.033 14.0 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MSP1_C PF07462.11 EPE30447.1 - 0.32 9.6 6.9 0.47 9.1 6.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Bac_luciferase PF00296.20 EPE30448.1 - 1.2e-56 192.5 0.1 2.1e-56 191.7 0.1 1.4 1 1 0 1 1 1 1 Luciferase-like monooxygenase Pyr_redox_2 PF07992.14 EPE30449.1 - 3e-52 177.7 0.8 4.1e-52 177.3 0.8 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EPE30449.1 - 1.2e-14 54.0 0.0 2.8e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EPE30449.1 - 2.9e-13 50.2 4.6 1.4e-12 48.0 0.6 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 EPE30449.1 - 8.6e-06 26.2 0.0 1.9e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.6 EPE30449.1 - 0.00072 18.8 0.1 1.3 8.1 0.0 2.5 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 EPE30449.1 - 0.0012 18.4 0.1 0.0019 17.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) NAD_binding_9 PF13454.6 EPE30449.1 - 0.0099 15.9 2.3 1.1 9.2 0.0 2.9 2 1 1 3 3 3 2 FAD-NAD(P)-binding LEA_5 PF00477.17 EPE30449.1 - 0.22 12.0 1.4 0.54 10.7 0.1 2.3 3 0 0 3 3 3 0 Small hydrophilic plant seed protein Fib_alpha PF08702.10 EPE30450.1 - 0.059 13.6 13.7 0.021 15.0 6.0 3.0 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FPP PF05911.11 EPE30450.1 - 0.25 9.5 22.7 0.2 9.8 21.0 1.6 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil IKKbetaNEMObind PF12179.8 EPE30450.1 - 1.8 8.7 4.8 5.5 7.1 0.3 3.0 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain V_ATPase_I PF01496.19 EPE30450.1 - 3.4 5.5 13.3 5.7 4.7 13.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin PF00261.20 EPE30450.1 - 9.5 5.5 36.5 1.9 7.8 14.3 2.4 1 1 1 2 2 2 0 Tropomyosin PNISR PF15996.5 EPE30451.1 - 0.0072 16.6 0.2 0.01 16.1 0.2 1.3 1 0 0 1 1 1 1 Arginine/serine-rich protein PNISR SesA PF17107.5 EPE30452.1 - 8.5e-06 26.0 0.1 2e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank PF00023.30 EPE30452.1 - 1.3e-05 25.4 0.4 9.3e-05 22.7 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EPE30452.1 - 2.2e-05 25.0 0.0 9e-05 23.0 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE30452.1 - 2.2e-05 24.6 0.1 5.5e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPE30452.1 - 3.7e-05 24.2 0.2 0.0002 21.8 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Helo_like_N PF17111.5 EPE30452.1 - 0.00081 18.8 0.3 0.0013 18.1 0.3 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_3 PF13606.6 EPE30452.1 - 0.036 14.6 0.6 0.23 12.1 0.1 2.7 2 0 0 2 2 2 0 Ankyrin repeat p450 PF00067.22 EPE30453.1 - 2.3e-52 178.3 0.0 3.2e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1764 PF08576.10 EPE30453.1 - 0.2 12.6 0.1 0.38 11.7 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) GMC_oxred_N PF00732.19 EPE30454.1 - 4.6e-54 183.8 0.0 3.9e-27 95.4 0.0 2.0 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE30454.1 - 2.9e-30 105.7 0.0 5.1e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EPE30454.1 - 3.3e-06 26.9 0.4 0.00011 22.0 0.0 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE30454.1 - 6.9e-06 26.2 0.1 2.1e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE30454.1 - 0.00037 19.7 0.1 0.048 12.7 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE30454.1 - 0.0029 16.9 0.3 0.017 14.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE30454.1 - 0.022 14.0 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EPE30454.1 - 0.065 11.9 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 EPE30454.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EPE30454.1 - 0.13 11.5 0.0 0.95 8.7 0.0 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE30454.1 - 0.54 10.8 2.5 0.87 10.2 0.0 2.4 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Oxysterol_BP PF01237.18 EPE30455.1 - 1.4e-60 205.1 1.5 5.6e-56 190.0 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein DUF5029 PF16432.5 EPE30455.1 - 0.087 12.4 0.1 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5029) CsbD PF05532.12 EPE30456.1 - 2.5e-14 52.9 28.2 2.4e-10 40.2 5.7 3.1 2 1 1 3 3 3 3 CsbD-like UPF0444 PF15475.6 EPE30456.1 - 0.005 17.1 10.5 0.17 12.2 0.3 3.2 3 1 0 3 3 3 2 Transmembrane protein C12orf23, UPF0444 Band_7 PF01145.25 EPE30457.1 - 2.7e-24 86.2 8.1 5.7e-24 85.1 8.1 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EPE30457.1 - 0.00023 20.3 4.6 0.0003 20.0 4.6 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial UcrQ PF02939.16 EPE30458.1 - 2.1e-34 117.3 0.2 2.4e-34 117.1 0.2 1.1 1 0 0 1 1 1 1 UcrQ family Ribosomal_L7Ae PF01248.26 EPE30459.1 - 5.8e-23 80.4 0.6 1.7e-22 79.0 0.6 1.8 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rib_recp_KP_reg PF05104.12 EPE30459.1 - 0.04 15.0 17.2 0.073 14.1 17.2 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region DHDPS PF00701.22 EPE30462.1 - 1.3e-32 112.7 0.0 1.7e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Amidohydro_2 PF04909.14 EPE30463.1 - 4.6e-27 95.5 0.0 9.7e-27 94.5 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase HET PF06985.11 EPE30464.1 - 2.5e-11 44.1 5.1 2.7e-10 40.8 0.6 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Hydrolase_6 PF13344.6 EPE30465.1 - 2e-23 82.4 0.0 3.8e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPE30465.1 - 1.6e-13 50.5 0.0 7e-13 48.4 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EPE30465.1 - 0.018 15.3 0.0 11 6.2 0.0 2.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase PriA_CRR PF18319.1 EPE30466.1 - 0.065 13.2 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 PriA DNA helicase Cys-rich region (CRR) domain AMPK1_CBM PF16561.5 EPE30467.1 - 0.00013 22.1 0.0 0.00029 21.0 0.0 1.5 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AP3D1 PF06375.11 EPE30467.1 - 0.024 14.9 6.6 0.043 14.1 6.6 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Neur_chan_memb PF02932.16 EPE30467.1 - 0.1 12.7 2.7 0.16 12.0 2.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 EPE30467.1 - 0.25 10.5 3.5 0.27 10.4 3.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EPE30467.1 - 0.58 8.9 5.1 0.63 8.8 5.1 1.2 1 0 0 1 1 1 0 Presenilin Sec3_C PF09763.9 EPE30467.1 - 0.8 8.0 5.3 0.87 7.9 5.3 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 Glyco_hydro_63 PF03200.16 EPE30468.1 - 1.4e-08 34.0 8.9 6.5e-07 28.5 0.6 3.9 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain OSCP PF00213.18 EPE30469.1 - 3.1e-45 154.4 1.2 3.7e-45 154.1 1.2 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Mog1 PF04603.12 EPE30469.1 - 0.1 12.9 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Ran-interacting Mog1 protein Mob1_phocein PF03637.17 EPE30470.1 - 4.2e-72 241.6 0.0 6.5e-72 241.0 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Rgp1 PF08737.10 EPE30471.1 - 1.1e-164 548.6 0.0 1.7e-164 548.0 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 EPE30471.1 - 0.0013 18.8 0.0 0.0035 17.4 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EPE30471.1 - 0.0074 16.7 0.0 0.038 14.4 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain SprT-like PF10263.9 EPE30473.1 - 0.011 15.6 0.1 0.022 14.6 0.1 1.6 1 1 0 1 1 1 0 SprT-like family SAM_2 PF07647.17 EPE30473.1 - 0.039 14.1 0.2 7 6.8 0.0 2.7 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) Peptidase_M91 PF14891.6 EPE30473.1 - 0.039 14.3 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 Effector protein SprT-like PF10263.9 EPE30474.1 - 0.063 13.1 0.2 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 SprT-like family Toxin_7 PF05980.12 EPE30475.1 - 0.018 15.3 6.6 0.027 14.7 6.6 1.3 1 0 0 1 1 1 0 Toxin 7 Atracotoxin PF05353.11 EPE30475.1 - 0.46 10.6 6.9 0.76 9.9 6.9 1.3 1 0 0 1 1 1 0 Delta Atracotoxin Conotoxin_I2 PF17557.2 EPE30475.1 - 0.5 10.5 7.9 0.77 9.9 7.9 1.3 1 0 0 1 1 1 0 I2-superfamily conotoxins Toxin_12 PF07740.12 EPE30475.1 - 0.73 10.6 9.2 1.3 9.8 9.2 1.5 1 1 0 1 1 1 0 Ion channel inhibitory toxin DIM1 PF02966.16 EPE30476.1 - 2.8e-69 231.0 0.1 3.5e-69 230.7 0.1 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 LIM_bind PF01803.16 EPE30478.1 - 8.7e-68 228.4 1.6 8.7e-68 228.4 1.6 5.1 3 2 2 5 5 5 1 LIM-domain binding protein HET PF06985.11 EPE30479.1 - 1.4e-34 119.5 0.9 2.1e-34 119.0 0.9 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 EPE30480.1 - 3.2e-17 62.8 0.0 4.5e-16 59.0 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE30480.1 - 1.7e-07 30.8 0.0 2.5e-06 26.9 0.0 2.4 2 1 1 3 3 3 1 Protein tyrosine kinase Ank_2 PF12796.7 EPE30481.1 - 2.5e-51 172.2 9.3 4.2e-17 62.5 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE30481.1 - 2.8e-41 134.8 1.6 0.00016 21.9 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.6 EPE30481.1 - 1.3e-40 137.3 0.6 9.6e-09 35.6 0.0 4.9 3 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EPE30481.1 - 7.6e-33 111.5 11.6 0.00024 21.4 0.3 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 EPE30481.1 - 1.7e-29 101.5 9.1 1e-07 32.1 0.8 7.2 1 1 6 7 7 7 7 Ankyrin repeats (many copies) SelA PF03841.13 EPE30481.1 - 0.019 14.0 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase Arg_repressor PF01316.21 EPE30481.1 - 0.17 11.6 1.9 19 5.1 0.2 4.1 4 1 0 4 4 4 0 Arginine repressor, DNA binding domain FA PF08736.11 EPE30481.1 - 0.51 10.5 3.8 5.9 7.1 0.1 3.8 4 0 0 4 4 4 0 FERM adjacent (FA) EccE PF11203.8 EPE30481.1 - 4.6 7.6 6.2 3.6 8.0 2.2 2.7 1 1 2 3 3 3 0 Putative type VII ESX secretion system translocon, EccE WW PF00397.26 EPE30483.1 - 4.2e-18 65.1 10.8 1.1e-06 28.6 0.0 4.1 4 0 0 4 4 4 3 WW domain Arm-DNA-bind_1 PF09003.10 EPE30483.1 - 0.026 14.7 0.1 3.8 7.7 0.0 2.7 2 0 0 2 2 2 0 Bacteriophage lambda integrase, Arm DNA-binding domain DUF4585 PF15232.6 EPE30483.1 - 0.082 13.0 0.0 5.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4585) Mit_ribos_Mrp51 PF11709.8 EPE30485.1 - 0.013 15.1 0.5 0.017 14.8 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DUF1104 PF06518.11 EPE30485.1 - 0.56 10.6 9.2 4.2 7.8 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Cerato-platanin PF07249.12 EPE30486.1 - 2.6e-56 188.8 2.6 3e-56 188.6 2.6 1.0 1 0 0 1 1 1 1 Cerato-platanin Coiled PF05710.12 EPE30486.1 - 1 10.2 9.1 3.9e+02 1.9 9.1 2.2 1 1 0 1 1 1 0 Coiled coil 2OG-FeII_Oxy_3 PF13640.6 EPE30487.1 - 1.2e-10 42.2 0.0 2.9e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-ANAPC11 PF12861.7 EPE30487.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger HET PF06985.11 EPE30488.1 - 6.3e-29 101.2 8.2 1.1e-28 100.5 8.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Herpes_ICP4_N PF03584.15 EPE30488.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region DUF4050 PF13259.6 EPE30491.1 - 3.2e-50 171.0 1.5 3.2e-50 171.0 1.5 2.4 2 2 0 2 2 2 1 Protein of unknown function (DUF4050) HET PF06985.11 EPE30492.1 - 1.6e-26 93.4 1.6 3.7e-26 92.2 0.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) JmjC PF02373.22 EPE30493.1 - 0.1 13.0 0.2 4.9 7.6 0.2 2.6 1 1 0 1 1 1 0 JmjC domain, hydroxylase SRP-alpha_N PF04086.13 EPE30493.1 - 0.22 11.4 9.5 0.35 10.8 9.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Med3 PF11593.8 EPE30493.1 - 6.7 5.8 5.9 11 5.1 5.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MBF2 PF15868.5 EPE30494.1 - 0.0075 16.8 0.0 0.012 16.1 0.0 1.5 1 1 0 1 1 1 1 Transcription activator MBF2 Pex14_N PF04695.13 EPE30496.1 - 8.4e-38 130.5 3.8 8.4e-38 130.5 3.8 3.0 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAPA-1 PF04795.12 EPE30498.1 - 4.2e-31 107.6 4.4 4.2e-31 107.6 4.4 3.4 4 0 0 4 4 4 2 PAPA-1-like conserved region SHQ1 PF04925.15 EPE30499.1 - 0.049 13.2 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 SHQ1 protein Myb_DNA-binding PF00249.31 EPE30501.1 - 4.1e-05 23.7 0.2 8.2e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPE30501.1 - 0.0003 21.0 1.6 0.00082 19.6 0.5 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EPE30501.1 - 0.002 18.5 0.8 0.0033 17.8 0.8 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 EPE30501.1 - 0.0086 17.0 0.4 0.015 16.3 0.4 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EPE30501.1 - 0.028 14.5 1.4 0.05 13.7 1.4 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPE30502.1 - 9.8e-05 22.5 0.7 0.00031 20.9 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EPE30502.1 - 0.0037 17.4 0.1 0.0095 16.1 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EPE30502.1 - 0.0058 17.0 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain 4HBT PF03061.22 EPE30507.1 - 1.1e-14 54.6 0.1 1.9e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 EPE30507.1 - 0.055 14.0 0.0 0.073 13.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily HMGL-like PF00682.19 EPE30508.1 - 5.6e-43 147.4 0.0 6.7e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 HMGL-like PAN_2 PF08276.11 EPE30509.1 - 0.00013 22.0 0.9 0.00041 20.4 0.8 2.0 1 1 0 1 1 1 1 PAN-like domain PAN_4 PF14295.6 EPE30509.1 - 0.0025 17.7 0.5 0.0077 16.1 0.5 1.8 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 EPE30509.1 - 0.0026 17.7 1.7 0.006 16.5 1.3 1.9 1 1 0 1 1 1 1 PAN domain HET PF06985.11 EPE30510.1 - 4e-24 85.6 3.6 6.1e-24 85.0 3.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1647 PF07801.11 EPE30510.1 - 0.073 12.8 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) Epimerase PF01370.21 EPE30511.1 - 3.8e-14 52.7 0.0 4.6e-13 49.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EPE30511.1 - 5.8e-08 32.2 0.0 1.9e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EPE30511.1 - 4.2e-07 30.0 0.0 1.3e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EPE30511.1 - 8.3e-06 25.4 0.1 0.00078 18.9 0.0 2.5 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EPE30511.1 - 2.4e-05 24.0 0.0 4.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EPE30511.1 - 0.00028 20.2 0.1 0.0026 17.0 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 EPE30511.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 EPE30511.1 - 0.2 10.7 0.0 0.45 9.5 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aldose_epim PF01263.20 EPE30512.1 - 3.1e-48 164.6 0.1 4.2e-48 164.2 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase ATP-synt_ab PF00006.25 EPE30513.1 - 1.8e-66 223.8 0.0 2.6e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EPE30513.1 - 1.2e-13 51.3 0.6 2.4e-13 50.4 0.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 EPE30513.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5535) Asp PF00026.23 EPE30514.1 - 2.1e-37 129.2 0.1 2.1e-37 129.2 0.1 2.9 2 1 0 2 2 2 1 Eukaryotic aspartyl protease HET PF06985.11 EPE30515.1 - 1.5e-06 28.6 0.0 2.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Miga PF10265.9 EPE30516.1 - 9.5 5.1 6.9 16 4.3 6.9 1.4 1 0 0 1 1 1 0 Mitoguardin Peroxidase_2 PF01328.17 EPE30517.1 - 2.2e-36 126.2 0.0 3.2e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 MDD_C PF18376.1 EPE30517.1 - 0.024 14.4 0.2 0.04 13.7 0.2 1.2 1 0 0 1 1 1 0 Mevalonate 5-diphosphate decarboxylase C-terminal domain PBP PF01161.20 EPE30519.1 - 8e-12 45.6 0.1 9.6e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glyco_transf_28 PF03033.20 EPE30522.1 - 3.2e-15 56.4 0.0 5.3e-14 52.4 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EPE30522.1 - 1.6e-06 27.2 0.1 2.6e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 EPE30522.1 - 0.0064 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 EPE30522.1 - 0.031 14.3 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF2985 PF11204.8 EPE30523.1 - 3.8e-39 132.7 0.5 3.8e-39 132.7 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) DUF981 PF06168.11 EPE30523.1 - 0.012 15.6 0.2 0.54 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF981) Phage_holin_3_6 PF07332.11 EPE30523.1 - 0.65 10.0 2.6 1.9 8.6 0.4 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SPX PF03105.19 EPE30524.1 - 1.9e-38 133.4 4.8 5.7e-26 92.3 1.7 2.2 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 EPE30524.1 - 9.6e-33 113.9 43.2 1.3e-32 113.4 43.2 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EPE30524.1 - 2e-27 96.2 67.4 4.5e-25 88.5 39.6 2.5 2 1 1 3 3 3 2 Citrate transporter APH PF01636.23 EPE30525.1 - 1.6e-18 67.5 0.0 2.5e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE30525.1 - 1.7e-06 27.8 0.0 3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EPE30525.1 - 0.002 17.5 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EPE30525.1 - 0.038 12.9 0.0 0.056 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) TPR_6 PF13174.6 EPE30525.1 - 0.15 12.7 0.0 0.79 10.5 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.22 EPE30527.1 - 6.7e-50 170.2 0.0 9e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EPE30528.1 - 5.2e-07 28.8 1.0 7.9e-06 24.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Aminotran_3 PF00202.21 EPE30529.1 - 1.8e-112 376.0 0.0 2.1e-112 375.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EPE30529.1 - 0.007 15.6 0.0 0.011 15.0 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Bestrophin PF01062.21 EPE30530.1 - 4.1e-39 134.7 0.0 7.8e-39 133.8 0.0 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Abhydrolase_3 PF07859.13 EPE30531.1 - 1.4e-34 119.8 0.0 4.3e-24 85.6 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EPE30531.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase Glyco_hydro_62 PF03664.13 EPE30533.1 - 9.5e-146 484.3 13.5 1.1e-145 484.1 13.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Abhydrolase_2 PF02230.16 EPE30534.1 - 0.035 13.9 0.1 0.071 12.9 0.0 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF1674 PF07896.12 EPE30538.1 - 6.7e-18 64.9 7.5 6.7e-18 64.9 7.5 2.6 2 2 1 3 3 3 1 Protein of unknown function (DUF1674) Trp_syntA PF00290.20 EPE30539.1 - 3.6e-97 324.3 0.2 7.5e-97 323.2 0.0 1.6 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 EPE30539.1 - 1.7e-49 168.8 1.3 3.3e-49 167.9 1.3 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rxt3 PF08642.10 EPE30540.1 - 1.3e-36 126.2 0.0 1.3e-36 126.2 0.0 3.0 3 0 0 3 3 3 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 EPE30540.1 - 0.00051 20.1 0.0 0.0059 16.7 0.0 2.3 1 1 0 1 1 1 1 LCCL domain Aminotran_3 PF00202.21 EPE30541.1 - 6e-88 295.2 0.2 6.7e-88 295.1 0.2 1.0 1 0 0 1 1 1 1 Aminotransferase class-III TetR_C_16 PF17920.1 EPE30541.1 - 0.056 13.7 0.8 7.4 6.9 0.1 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF829 PF05705.14 EPE30542.1 - 3.3e-39 135.2 0.0 3.9e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) CLN3 PF02487.17 EPE30544.1 - 8e-159 528.9 6.0 9.4e-159 528.7 6.0 1.0 1 0 0 1 1 1 1 CLN3 protein AA_permease_2 PF13520.6 EPE30545.1 - 1e-59 202.5 40.1 1e-57 195.9 40.1 2.1 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE30545.1 - 4.3e-16 58.6 23.2 4.3e-16 58.6 23.2 2.1 1 1 1 2 2 2 2 Amino acid permease APA3_viroporin PF11289.8 EPE30545.1 - 0.11 12.0 1.5 0.24 10.9 1.5 1.4 1 0 0 1 1 1 0 Coronavirus accessory protein 3a PPTA PF01239.22 EPE30547.1 - 1e-29 101.4 6.1 2.9e-06 26.8 2.0 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Sporozoite_P67 PF05642.11 EPE30547.1 - 0.093 10.8 0.7 0.12 10.5 0.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ANAPC4_WD40 PF12894.7 EPE30548.1 - 5.1e-07 29.9 0.2 0.11 12.8 0.0 4.0 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPE30548.1 - 0.0013 19.5 4.5 0.13 13.1 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EPE30548.1 - 0.3 10.1 0.0 0.5 9.4 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region His_Phos_2 PF00328.22 EPE30549.1 - 0.066 12.5 0.1 0.75 9.1 0.0 2.3 2 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) YwqJ-deaminase PF14431.6 EPE30551.1 - 0.079 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 YwqJ-like deaminase F-box-like PF12937.7 EPE30551.1 - 0.099 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 EPE30552.1 - 0.00017 21.4 0.1 0.00037 20.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like Dynactin PF12455.8 EPE30553.1 - 4.4e-113 377.3 3.9 4.4e-113 377.3 3.9 2.5 2 0 0 2 2 2 1 Dynein associated protein CAP_GLY PF01302.25 EPE30553.1 - 1.4e-21 76.3 0.2 2.5e-21 75.4 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain F_actin_bind PF08919.10 EPE30553.1 - 0.018 15.2 8.0 1.5 8.9 0.3 4.7 4 0 0 4 4 4 0 F-actin binding Ribosomal_S6e PF01092.19 EPE30555.1 - 2.1e-59 198.9 0.1 4.7e-59 197.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Atg14 PF10186.9 EPE30555.1 - 0.26 10.3 6.0 0.34 9.9 6.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ctf8 PF09696.10 EPE30556.1 - 6.9e-42 143.1 0.2 1.1e-41 142.5 0.2 1.3 1 1 0 1 1 1 1 Ctf8 DUF1128 PF06569.11 EPE30556.1 - 0.19 11.8 0.0 0.29 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) Cupin_2 PF07883.11 EPE30557.1 - 0.00084 19.0 0.1 0.0024 17.6 0.1 1.7 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EPE30557.1 - 0.0021 17.7 0.0 0.0055 16.3 0.0 1.6 1 1 0 1 1 1 1 Cupin SesA PF17107.5 EPE30559.1 - 2.9e-11 43.6 0.5 2.9e-11 43.6 0.5 2.1 1 1 1 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_2 PF12796.7 EPE30559.1 - 5.7e-09 36.5 0.0 1.5e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Helo_like_N PF17111.5 EPE30559.1 - 6e-09 35.6 4.7 8.5e-09 35.1 4.7 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_5 PF13857.6 EPE30559.1 - 3.7e-05 23.9 0.0 8.5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPE30559.1 - 3.9e-05 24.1 0.0 0.00013 22.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE30559.1 - 0.00014 22.0 0.0 0.00056 20.2 0.0 2.1 2 0 0 2 2 1 1 Ankyrin repeat Ank PF00023.30 EPE30559.1 - 0.00036 20.8 0.0 0.0012 19.2 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat COG2 PF06148.11 EPE30559.1 - 0.087 12.9 1.1 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PuR_N PF09182.10 EPE30559.1 - 0.13 12.2 0.1 0.66 9.9 0.1 2.2 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal TBPIP PF07106.13 EPE30559.1 - 0.2 11.6 1.2 18 5.3 0.0 3.3 4 0 0 4 4 4 0 TBPIP/Hop2 winged helix domain Peptidase_C98 PF15499.6 EPE30559.1 - 0.41 10.1 4.9 2.1 7.8 2.1 2.6 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DHR10 PF18595.1 EPE30559.1 - 1.2 9.3 12.3 0.13 12.4 1.0 2.6 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain FUSC PF04632.12 EPE30559.1 - 5.9 5.3 5.3 41 2.5 2.0 1.9 1 1 0 1 1 1 0 Fusaric acid resistance protein family Zn_clus PF00172.18 EPE30560.1 - 1.2e-08 34.9 12.4 2.9e-08 33.7 12.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE30560.1 - 7e-07 28.5 0.1 1.3e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CNDH2_C PF16858.5 EPE30560.1 - 0.084 12.7 1.5 0.13 12.1 1.5 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term MFS_1 PF07690.16 EPE30561.1 - 4e-40 137.8 49.3 7.7e-39 133.6 48.3 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3382 PF11862.8 EPE30561.1 - 0.28 11.5 0.1 0.28 11.5 0.1 3.5 4 1 0 4 4 4 0 Domain of unknown function (DUF3382) NPP1 PF05630.11 EPE30562.1 - 1.8e-60 204.4 0.0 2.1e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Phosphoesterase PF04185.14 EPE30565.1 - 1.1e-31 110.4 0.3 9.6e-31 107.2 0.3 1.9 1 1 0 1 1 1 1 Phosphoesterase family Sulfatase PF00884.23 EPE30565.1 - 0.0074 15.7 0.2 0.011 15.1 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Pribosyltran_N PF13793.6 EPE30566.1 - 4.5e-44 149.1 0.3 1.8e-43 147.1 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EPE30566.1 - 9e-41 139.9 2.1 3.4e-33 115.2 1.5 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EPE30566.1 - 2.8e-15 56.2 1.7 6.5e-15 55.0 0.8 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EPE30566.1 - 0.0088 15.5 0.2 0.015 14.7 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF913 PF06025.12 EPE30567.1 - 1.4e-140 468.5 0.0 1.4e-140 468.5 0.0 7.2 8 1 0 8 8 8 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 EPE30567.1 - 2e-120 402.5 6.9 2e-120 402.5 6.9 4.0 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) HECT PF00632.25 EPE30567.1 - 1.1e-95 320.6 0.0 2.5e-95 319.5 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 EPE30567.1 - 1.5e-29 100.5 24.5 5.3e-11 41.6 1.2 4.5 4 0 0 4 4 4 3 Ubiquitin binding region UBA PF00627.31 EPE30567.1 - 0.038 13.9 0.1 0.13 12.2 0.1 2.0 1 0 0 1 1 1 0 UBA/TS-N domain RabGAP-TBC PF00566.18 EPE30568.1 - 2.6e-49 167.8 0.2 2.6e-49 167.8 0.2 2.9 2 2 1 3 3 3 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 EPE30568.1 - 0.0016 18.6 23.4 0.0041 17.3 8.9 2.8 1 1 1 2 2 2 2 Centrosomin N-terminal motif 1 HALZ PF02183.18 EPE30568.1 - 0.41 10.9 19.9 1.2 9.5 0.5 3.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper YabA PF06156.13 EPE30568.1 - 2.3 8.9 19.9 5.5 7.7 7.1 2.9 1 1 1 2 2 2 0 Initiation control protein YabA Prominin PF05478.11 EPE30568.1 - 8.6 4.2 12.9 13 3.6 12.9 1.2 1 0 0 1 1 1 0 Prominin Jnk-SapK_ap_N PF09744.9 EPE30568.1 - 9.6 6.4 39.2 0.032 14.5 18.7 2.7 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 MFS_1 PF07690.16 EPE30569.1 - 4.5e-24 85.0 34.3 4.5e-24 85.0 34.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4334 PF14232.6 EPE30571.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4334) GCN5L1 PF06320.13 EPE30573.1 - 4.5e-16 59.0 0.2 7.3e-16 58.3 0.2 1.3 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Hamartin PF04388.12 EPE30573.1 - 0.11 11.1 4.6 0.1 11.3 4.6 1.2 1 0 0 1 1 1 0 Hamartin protein Ribosomal_S8e PF01201.22 EPE30574.1 - 6e-53 178.7 0.9 7.1e-53 178.5 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.6 EPE30574.1 - 0.11 13.5 1.3 0.31 12.0 0.2 2.1 2 0 0 2 2 2 0 Small acidic protein family Methyltransf_2 PF00891.18 EPE30575.1 - 1.1e-18 67.4 0.1 2.7e-18 66.1 0.0 1.5 1 1 1 2 2 2 1 O-methyltransferase domain CheR PF01739.18 EPE30575.1 - 0.19 11.2 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_23 PF13489.6 EPE30576.1 - 1.8e-18 66.9 0.0 3.6e-18 65.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE30576.1 - 4.9e-11 43.2 0.0 3.8e-10 40.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE30576.1 - 8.7e-10 39.1 0.0 2.3e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE30576.1 - 3.2e-08 34.2 0.0 5.1e-07 30.4 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE30576.1 - 3.7e-08 33.3 0.0 0.0061 16.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_2 PF00891.18 EPE30576.1 - 0.00051 19.4 0.0 0.0091 15.3 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain Ubie_methyltran PF01209.18 EPE30576.1 - 0.0036 16.7 0.0 0.087 12.1 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EPE30576.1 - 0.0073 15.8 0.2 0.028 13.9 0.0 2.0 3 0 0 3 3 3 1 Putative methyltransferase PrmA PF06325.13 EPE30576.1 - 0.024 14.0 0.2 0.085 12.2 0.0 1.9 1 1 1 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EPE30576.1 - 0.04 13.5 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 EPE30576.1 - 0.095 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CMAS PF02353.20 EPE30576.1 - 0.15 11.3 0.0 0.38 10.0 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase HTH_20 PF12840.7 EPE30576.1 - 0.17 12.0 0.1 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Aldo_ket_red PF00248.21 EPE30579.1 - 2.3e-54 184.6 0.0 2.6e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LmjF365940-deam PF14421.6 EPE30580.1 - 4.9 6.7 7.1 24 4.4 0.1 3.3 2 1 0 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases His_Phos_1 PF00300.22 EPE30581.1 - 1e-23 84.0 0.0 1.6e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) WD40 PF00400.32 EPE30582.1 - 8.1e-46 153.1 28.4 1.4e-09 38.4 0.8 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE30582.1 - 3e-11 43.5 0.7 0.006 16.9 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPE30582.1 - 6.6e-07 28.3 0.0 0.00053 18.8 0.0 3.5 3 1 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EPE30582.1 - 8.7e-06 24.7 0.1 0.053 12.3 0.0 2.9 2 1 0 3 3 3 2 Nup133 N terminal like bZIP_1 PF00170.21 EPE30582.1 - 0.0037 17.3 0.4 0.0067 16.5 0.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor tRNA-synt_1 PF00133.22 EPE30583.1 - 4.8e-34 117.6 0.0 2.1e-22 79.1 0.0 4.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EPE30583.1 - 1e-16 60.7 0.4 4.2e-10 38.9 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EPE30583.1 - 6.7e-12 45.6 0.6 6.7e-12 45.6 0.6 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EPE30583.1 - 7.1e-08 32.2 0.0 1.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Clat_adaptor_s PF01217.20 EPE30584.1 - 7.4e-44 149.1 0.0 1.5e-43 148.2 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Peptidase_S58 PF03576.14 EPE30584.1 - 0.052 13.1 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S58 Frataxin_Cyay PF01491.16 EPE30585.1 - 1.8e-34 118.1 0.0 2.2e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain zf-CSL PF05207.13 EPE30586.1 - 1.9e-21 75.5 0.3 2.4e-21 75.2 0.3 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 EPE30586.1 - 0.00041 20.4 0.2 0.0007 19.7 0.2 1.3 1 0 0 1 1 1 1 Zinc ribbon domain Terminase_GpA PF05876.12 EPE30586.1 - 0.18 10.3 0.1 0.21 10.1 0.1 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Prok-RING_1 PF14446.6 EPE30586.1 - 0.56 10.2 2.7 1 9.3 2.7 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_clus PF00172.18 EPE30587.1 - 3.8e-07 30.1 6.1 7.1e-07 29.2 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE30587.1 - 0.00047 19.1 0.0 0.0011 17.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain FGGY_C PF02782.16 EPE30589.1 - 9.5e-76 253.9 3.9 1.5e-75 253.3 1.3 2.3 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EPE30589.1 - 2.1e-67 227.2 0.0 2.8e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.20 EPE30590.1 - 1.5e-53 181.8 7.7 1.8e-53 181.6 7.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein ABC_membrane_2 PF06472.15 EPE30591.1 - 3.2e-101 338.3 0.9 4.7e-101 337.7 0.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EPE30591.1 - 1.6e-18 67.6 0.0 3.6e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EPE30591.1 - 8.2e-05 22.6 0.1 0.0006 19.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EPE30591.1 - 0.021 15.3 0.3 0.065 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EPE30591.1 - 0.037 13.4 0.2 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 EPE30591.1 - 0.039 13.5 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EPE30591.1 - 0.04 13.7 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EPE30591.1 - 0.061 13.7 0.7 0.26 11.7 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain RuvB_N PF05496.12 EPE30591.1 - 0.095 12.4 0.0 0.55 10.0 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EPE30591.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MFS_1 PF07690.16 EPE30593.1 - 8.9e-24 84.1 19.3 8.9e-24 84.1 19.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily ApoL PF05461.11 EPE30593.1 - 0.28 10.4 0.1 0.84 8.9 0.1 1.7 2 0 0 2 2 2 0 Apolipoprotein L Connexin PF00029.19 EPE30594.1 - 0.0025 17.6 0.1 0.0029 17.4 0.1 1.0 1 0 0 1 1 1 1 Connexin ETRAMP PF09716.10 EPE30594.1 - 0.036 14.1 0.4 0.055 13.5 0.4 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) LapA_dom PF06305.11 EPE30594.1 - 0.045 13.6 0.1 0.089 12.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 EPE30594.1 - 0.18 12.7 0.8 2 9.4 0.3 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain adh_short PF00106.25 EPE30595.1 - 7.7e-21 74.4 0.0 1.4e-17 63.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE30595.1 - 1.7e-09 37.6 0.0 1.8e-08 34.3 0.0 1.9 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE30595.1 - 0.00032 20.6 0.0 0.00063 19.7 0.0 1.4 1 0 0 1 1 1 1 KR domain PS_Dcarbxylase PF02666.15 EPE30596.1 - 9.9e-55 185.2 0.0 1.3e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M35 PF02102.15 EPE30598.1 - 2.1e-103 346.0 26.8 2.5e-103 345.7 26.8 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EPE30598.1 - 1.3e-41 142.5 9.4 2.9e-41 141.4 9.4 1.6 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase CARDB PF07705.11 EPE30598.1 - 0.11 12.7 0.8 0.48 10.7 0.1 2.4 2 1 0 2 2 2 0 CARDB DUF1398 PF07166.11 EPE30598.1 - 0.2 11.7 0.7 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1398) TAN PF11640.8 EPE30598.1 - 0.47 10.6 2.2 1.6 8.8 2.2 1.8 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair TERB2 PF15101.6 EPE30599.1 - 2.6 8.1 10.0 3.5 7.6 10.0 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pkinase PF00069.25 EPE30600.1 - 3.3e-34 118.4 0.0 4.9e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE30600.1 - 6.3e-20 71.5 0.0 8.7e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPE30600.1 - 0.00022 21.2 0.1 0.00044 20.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EPE30600.1 - 0.095 11.5 0.0 0.21 10.4 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EPE30600.1 - 0.095 12.0 0.1 0.2 11.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 EPE30601.1 - 1.2e-19 70.5 36.7 1.6e-13 50.3 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE30601.1 - 3e-11 42.8 21.7 1.1e-10 41.0 21.0 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Fasciclin PF02469.22 EPE30602.1 - 1.5e-45 154.5 1.7 1.4e-24 86.8 0.0 2.4 2 1 0 2 2 2 2 Fasciclin domain MFS_1 PF07690.16 EPE30603.1 - 2.4e-18 66.2 36.5 2.7e-09 36.4 10.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EPE30604.1 - 1.5e-60 205.3 0.1 1.9e-60 204.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 EPE30605.1 - 8.5e-34 117.0 0.1 1.6e-33 116.1 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2470 PF10615.9 EPE30606.1 - 1.9e-21 76.5 0.1 2.8e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 EPE30606.1 - 0.0068 16.7 0.3 0.016 15.5 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) 6PF2K PF01591.18 EPE30607.1 - 6.7e-80 267.6 0.1 9.2e-80 267.1 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EPE30607.1 - 1.3e-37 129.4 0.0 2.6e-37 128.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 EPE30607.1 - 0.00051 19.6 0.0 0.0038 16.7 0.0 1.9 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EPE30607.1 - 0.00074 19.7 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Lar_N PF09861.9 EPE30607.1 - 0.075 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Lactate racemase N-terminal domain Pim PF16765.5 EPE30607.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Pesticin immunity protein DUF3328 PF11807.8 EPE30610.1 - 7.6e-60 202.4 2.0 1e-59 202.0 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) YjcZ PF13990.6 EPE30610.1 - 0.15 11.4 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 YjcZ-like protein Herpes_UL73 PF03554.13 EPE30610.1 - 0.16 12.0 1.1 0.39 10.8 1.1 1.6 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein DUF3328 PF11807.8 EPE30611.1 - 6e-22 78.5 2.8 1.9e-21 76.8 2.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EPE30612.1 - 5.4e-52 176.7 0.3 7.5e-52 176.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF5338 PF17273.2 EPE30613.1 - 0.00017 21.6 0.4 10 6.3 0.0 3.2 3 0 0 3 3 3 3 Family of unknown function (DUF5338) DUF2155 PF09923.9 EPE30613.1 - 0.0038 17.4 0.0 11 6.4 0.0 3.0 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2155) Bac_DNA_binding PF00216.21 EPE30613.1 - 0.0069 16.6 0.1 15 5.8 0.0 2.9 1 1 2 3 3 3 1 Bacterial DNA-binding protein TetR_C_13 PF16925.5 EPE30613.1 - 0.012 15.6 1.0 17 5.4 0.0 2.9 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain QIL1 PF15884.5 EPE30613.1 - 0.018 15.6 0.7 1.8 9.2 0.1 2.4 1 1 1 2 2 2 0 MICOS complex subunit MIC13, QIL1 Sigma70_r3 PF04539.16 EPE30613.1 - 0.049 13.7 7.4 13 6.0 0.2 3.2 3 0 0 3 3 3 0 Sigma-70 region 3 SRP19 PF01922.17 EPE30613.1 - 0.19 12.7 1.7 86 4.2 0.1 3.0 1 1 2 3 3 3 0 SRP19 protein Auto_anti-p27 PF06677.12 EPE30613.1 - 0.19 11.9 0.0 1.3e+02 2.8 0.0 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF1442 PF07279.11 EPE30613.1 - 0.22 10.8 1.9 8.7 5.6 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1442) DUF1611_N PF17396.2 EPE30613.1 - 0.22 11.7 1.6 2 8.7 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain DUF3328 PF11807.8 EPE30614.1 - 9.6e-22 77.8 0.3 1.4e-21 77.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EPE30615.1 - 2.5e-23 83.0 2.3 3.3e-23 82.6 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EPE30616.1 - 2.5e-25 89.6 3.4 9.2e-25 87.7 3.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) NigD_N PF12667.7 EPE30616.1 - 0.093 12.8 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 NigD-like N-terminal OB domain Ank PF00023.30 EPE30617.1 - 4.8e-20 71.1 0.0 6e-06 26.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EPE30617.1 - 1.6e-19 70.2 0.1 6.4e-14 52.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE30617.1 - 2.6e-15 55.0 0.0 0.0013 19.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EPE30617.1 - 6.7e-15 55.2 0.0 8.1e-11 42.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE30617.1 - 1.9e-13 50.3 0.0 6.5e-05 23.1 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) bZIP_1 PF00170.21 EPE30617.1 - 0.07 13.2 6.6 0.2 11.7 6.6 1.8 1 0 0 1 1 1 0 bZIP transcription factor DUF4955 PF16315.5 EPE30617.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4955) TPR_12 PF13424.6 EPE30618.1 - 0.001 19.3 0.2 0.0069 16.7 0.0 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat MFS_1 PF07690.16 EPE30619.1 - 9.9e-21 74.0 13.3 1.3e-20 73.6 13.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sulfatase PF00884.23 EPE30620.1 - 1e-46 159.8 1.3 7.5e-45 153.6 0.0 2.3 2 1 0 2 2 2 1 Sulfatase DUF4976 PF16347.5 EPE30620.1 - 7.3e-06 26.2 0.4 0.0016 18.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 EPE30620.1 - 0.00021 21.0 0.0 0.0014 18.3 0.0 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Thioredox_DsbH PF03190.15 EPE30620.1 - 0.0013 18.7 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 DUF229 PF02995.17 EPE30620.1 - 0.043 12.4 0.0 0.056 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) NUDIX PF00293.28 EPE30621.1 - 5.5e-06 26.5 0.0 9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain HET PF06985.11 EPE30622.1 - 2.6e-24 86.3 0.3 6e-24 85.1 0.3 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_N PF08240.12 EPE30623.1 - 1e-17 63.9 3.4 1e-17 63.9 3.4 2.1 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE30623.1 - 3e-13 49.9 0.0 6.1e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EPE30623.1 - 2.6e-05 23.6 0.0 5.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EPE30623.1 - 0.009 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EPE30623.1 - 0.018 14.9 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EPE30623.1 - 0.083 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 EPE30623.1 - 0.12 11.7 0.2 0.21 10.9 0.2 1.3 1 0 0 1 1 1 0 ThiF family Fungal_trans_2 PF11951.8 EPE30624.1 - 0.048 12.5 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_transf_8 PF01501.20 EPE30625.1 - 6.8e-07 29.1 0.0 1.8e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EPE30625.1 - 0.042 13.2 0.1 0.068 12.5 0.1 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative PsaD PF02531.16 EPE30625.1 - 0.056 13.0 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 PsaD FAD_binding_3 PF01494.19 EPE30626.1 - 1.5e-81 274.4 0.0 2e-81 274.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE30626.1 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE30626.1 - 0.0021 17.3 0.0 0.0035 16.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EPE30626.1 - 0.0023 17.6 0.5 0.079 12.5 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPE30626.1 - 0.0067 15.5 0.1 0.01 14.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EPE30626.1 - 0.007 16.6 0.9 0.018 15.2 0.9 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPE30626.1 - 0.035 13.1 0.1 0.065 12.3 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EPE30626.1 - 0.086 11.9 0.4 0.12 11.4 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyoxalase PF00903.25 EPE30627.1 - 1.1e-10 41.8 3.6 1e-08 35.4 2.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EPE30627.1 - 0.034 14.4 0.1 9.6 6.5 0.0 2.9 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily F-box-like PF12937.7 EPE30628.1 - 0.0047 16.8 2.2 0.016 15.0 0.6 2.7 2 1 0 2 2 2 1 F-box-like PAXNEB PF05625.11 EPE30628.1 - 0.076 12.1 0.2 0.17 11.0 0.1 1.6 2 0 0 2 2 2 0 PAXNEB protein Bromodomain PF00439.25 EPE30629.1 - 6.1e-06 26.2 0.0 2.9e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 Bromodomain ATG16 PF08614.11 EPE30630.1 - 0.0041 17.4 0.3 0.0071 16.6 0.3 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ABC_tran_CTD PF16326.5 EPE30630.1 - 0.066 13.5 0.6 0.15 12.4 0.6 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain SlyX PF04102.12 EPE30630.1 - 0.64 10.7 8.6 3.7 8.2 8.6 2.1 1 1 0 1 1 1 0 SlyX Steroid_dh PF02544.16 EPE30631.1 - 4.7e-30 104.6 0.8 7.2e-30 104.0 0.8 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1418 PF07214.12 EPE30631.1 - 0.0012 18.6 0.2 0.0025 17.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1418) DUF1295 PF06966.12 EPE30631.1 - 0.0014 18.2 0.5 0.0032 17.0 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EPE30631.1 - 0.0017 18.7 0.0 0.0049 17.2 0.0 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase DOCK_N PF16172.5 EPE30632.1 - 5.2e-123 410.7 0.5 7.4e-123 410.2 0.5 1.2 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 EPE30632.1 - 2.9e-38 131.6 0.0 5.3e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 EPE30632.1 - 5.5e-05 22.7 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPE30632.1 - 0.00011 21.9 0.1 0.00092 19.0 0.0 2.4 3 0 0 3 3 3 1 Variant SH3 domain DHR-2 PF06920.13 EPE30633.1 - 7.5e-39 133.8 7.2 3.1e-38 131.7 4.9 2.5 2 1 0 2 2 2 1 Dock homology region 2 Hydin_ADK PF17213.3 EPE30633.1 - 1.2 9.3 4.0 2.5 8.3 4.0 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MFS_1 PF07690.16 EPE30634.1 - 1.7e-37 129.2 46.9 2e-36 125.7 48.3 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily HCV_NS4a PF01006.20 EPE30634.1 - 1.4 8.7 4.3 4.7 7.0 4.3 1.9 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a 4HBT_2 PF13279.6 EPE30635.1 - 2.3e-08 34.5 0.0 3.9e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily TMEM191C PF15194.6 EPE30635.1 - 0.0085 16.3 0.9 0.22 11.7 0.0 2.3 2 0 0 2 2 2 1 TMEM191C family GrpE PF01025.19 EPE30637.1 - 2.6e-44 150.8 6.1 3.8e-44 150.3 6.1 1.2 1 0 0 1 1 1 1 GrpE PMC2NT PF08066.12 EPE30637.1 - 0.17 12.6 3.2 0.34 11.6 2.6 1.8 1 1 0 1 1 1 0 PMC2NT (NUC016) domain Reprolysin_5 PF13688.6 EPE30641.1 - 5.5e-59 199.6 8.6 5.5e-59 199.6 8.6 2.4 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EPE30641.1 - 2.4e-52 177.7 3.7 4.6e-52 176.7 3.7 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EPE30641.1 - 5e-44 150.4 4.8 1e-43 149.3 4.8 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EPE30641.1 - 5e-15 56.0 30.3 5e-15 56.0 30.3 5.2 4 2 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 EPE30641.1 - 9.9e-12 45.5 0.1 2.3e-11 44.3 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 EPE30641.1 - 0.00013 21.9 10.1 0.0037 17.2 10.1 3.0 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease ADAM_CR_2 PF17771.1 EPE30641.1 - 0.00028 21.3 14.5 0.00028 21.3 14.5 5.0 1 1 2 3 3 3 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 EPE30641.1 - 0.00066 19.9 0.1 0.0015 18.8 0.1 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide TMIE PF16038.5 EPE30641.1 - 0.15 11.9 2.2 0.31 10.9 2.2 1.4 1 0 0 1 1 1 0 TMIE protein AMP-binding PF00501.28 EPE30642.1 - 1.3e-89 300.7 0.3 1.6e-89 300.4 0.3 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE30642.1 - 4.3e-28 98.1 1.0 2.4e-26 92.5 0.8 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EPE30642.1 - 5.9e-19 67.7 1.5 5.9e-19 67.7 1.5 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 EPE30642.1 - 0.11 12.4 0.0 0.68 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Aspzincin_M35 PF14521.6 EPE30643.1 - 5.2e-06 27.1 4.2 1.1e-05 26.0 4.2 1.6 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase DUF695 PF05117.12 EPE30643.1 - 0.036 14.2 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF695) Peptidase_M35 PF02102.15 EPE30643.1 - 0.13 11.1 5.2 0.42 9.4 1.3 2.1 2 0 0 2 2 2 0 Deuterolysin metalloprotease (M35) family tRNA-synt_2d PF01409.20 EPE30645.1 - 6e-47 160.2 0.5 8e-26 91.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EPE30645.1 - 1.6e-26 92.5 0.0 3.6e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.27 EPE30646.1 - 9.7e-58 192.1 0.1 1e-19 70.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Polysacc_synt_3 PF13440.6 EPE30646.1 - 0.17 11.1 0.0 0.59 9.3 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RNA_pol_A_bac PF01000.26 EPE30647.1 - 3e-32 111.3 0.0 4.7e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EPE30647.1 - 5.2e-20 70.7 0.0 7.7e-20 70.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Calcipressin PF04847.12 EPE30648.1 - 3.5e-47 160.6 0.0 5e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.8 EPE30648.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 DUF2236 PF09995.9 EPE30649.1 - 1.8e-33 116.7 0.7 2.7e-33 116.1 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) RRP7 PF12923.7 EPE30649.1 - 0.034 14.3 0.3 0.055 13.6 0.3 1.3 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain WD40 PF00400.32 EPE30650.1 - 3e-20 72.2 3.2 6.3e-05 23.7 0.0 8.4 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE30650.1 - 2e-06 28.0 0.9 1.1 9.7 0.1 6.8 8 0 0 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EPE30650.1 - 0.024 14.6 0.3 2.1 8.4 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Neugrin PF06413.11 EPE30651.1 - 5.6e-13 49.4 0.3 5.6e-13 49.4 0.3 1.7 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 EPE30651.1 - 1.2e-06 28.8 0.2 3.2e-06 27.4 0.2 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF1590 PF07629.11 EPE30653.1 - 0.14 12.0 0.4 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) OTT_1508_deam PF14441.6 EPE30654.1 - 2.5e-19 69.0 0.1 5.3e-19 68.0 0.1 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase MaoC_dehydratas PF01575.19 EPE30655.1 - 7.6e-17 61.0 0.0 1.3e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain 4HBT PF03061.22 EPE30655.1 - 0.039 14.3 0.1 0.078 13.3 0.1 1.5 1 0 0 1 1 1 0 Thioesterase superfamily Acetyltransf_8 PF13523.6 EPE30656.1 - 9.1e-49 164.9 0.4 1.4e-48 164.3 0.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 EPE30657.1 - 3.9e-97 325.5 0.0 4.7e-97 325.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE30657.1 - 5.7e-10 40.0 0.0 1.3e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain K_oxygenase PF13434.6 EPE30658.1 - 4.9e-41 141.0 0.0 5.8e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Mqo PF06039.15 EPE30658.1 - 0.00016 20.4 0.0 0.049 12.2 0.0 2.2 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) ABC_membrane PF00664.23 EPE30659.1 - 3.9e-89 298.9 25.5 1.3e-46 159.5 5.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EPE30659.1 - 3.7e-61 205.6 0.0 8.8e-30 104.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EPE30659.1 - 4.3e-13 49.2 0.4 0.0054 16.2 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EPE30659.1 - 7.7e-07 28.8 0.6 0.03 14.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EPE30659.1 - 1.6e-06 28.4 0.2 0.28 11.4 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EPE30659.1 - 4.4e-06 27.2 5.3 0.013 15.9 1.2 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EPE30659.1 - 5.5e-05 22.8 0.1 1.1 8.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EPE30659.1 - 5.7e-05 23.1 0.0 0.044 13.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 EPE30659.1 - 6e-05 23.0 4.2 0.015 15.1 0.0 4.4 5 0 0 5 5 5 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EPE30659.1 - 8.9e-05 22.3 0.0 0.19 11.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EPE30659.1 - 0.00019 20.8 0.1 0.57 9.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.6 EPE30659.1 - 0.00026 21.1 0.0 0.15 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 EPE30659.1 - 0.001 19.0 0.1 0.11 12.4 0.1 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase ABC_ATPase PF09818.9 EPE30659.1 - 0.0012 17.7 0.4 0.0086 14.9 0.0 2.4 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA PF00004.29 EPE30659.1 - 0.0013 19.1 0.1 15 6.0 0.0 4.3 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EPE30659.1 - 0.0037 17.8 0.0 0.18 12.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EPE30659.1 - 0.0047 17.5 0.0 1.3 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EPE30659.1 - 0.011 16.0 0.6 7.5 6.9 0.1 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 EPE30659.1 - 0.012 15.6 0.0 8.1 6.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 EPE30659.1 - 0.019 15.0 0.1 0.78 9.8 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_17 PF13207.6 EPE30659.1 - 0.022 15.2 0.1 6 7.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain KdpD PF02702.17 EPE30659.1 - 0.044 13.3 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain AAA_15 PF13175.6 EPE30659.1 - 0.064 13.0 0.0 2.4 7.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 EPE30659.1 - 0.094 12.3 0.0 18 4.9 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EPE30659.1 - 0.11 12.2 0.0 13 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 EPE30659.1 - 0.11 11.6 0.0 4.8 6.2 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 EPE30659.1 - 0.18 11.3 0.1 15 5.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DPBB_1 PF03330.18 EPE30660.1 - 5.2e-06 26.6 0.9 4.4e-05 23.7 0.9 2.1 1 1 0 1 1 1 1 Lytic transglycolase zinc_ribbon_2 PF13240.6 EPE30660.1 - 0.39 10.5 5.1 4.6 7.1 0.1 3.5 4 0 0 4 4 4 0 zinc-ribbon domain 2OG-FeII_Oxy_2 PF13532.6 EPE30661.1 - 2.9e-26 92.9 0.0 5.2e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 EPE30661.1 - 4.8e-25 88.7 0.0 3.4e-23 82.7 0.0 2.4 1 1 0 1 1 1 1 Isochorismatase family GST_C_3 PF14497.6 EPE30661.1 - 2.4e-06 27.7 0.0 5.5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPE30661.1 - 0.029 14.4 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ECH_1 PF00378.20 EPE30662.1 - 2e-41 142.0 0.0 1.9e-40 138.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPE30662.1 - 1.3e-33 116.9 0.0 5.8e-31 108.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase RE_AccI PF09545.10 EPE30662.1 - 0.052 12.5 0.0 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 AccI restriction endonuclease TAF8_C PF10406.9 EPE30663.1 - 4.5e-19 68.7 0.8 2.1e-18 66.6 0.8 2.3 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 EPE30663.1 - 7.9e-08 32.2 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated SKN1 PF03935.15 EPE30666.1 - 7.4e-223 740.5 0.7 8.8e-223 740.2 0.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF1751 PF08551.10 EPE30667.1 - 5.3e-26 91.1 4.3 1.1e-25 90.1 4.3 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) WD40 PF00400.32 EPE30668.1 - 4.1e-15 55.9 3.1 0.05 14.5 0.1 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE30668.1 - 1.6e-09 37.9 0.1 0.23 11.8 0.0 5.6 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EPE30668.1 - 0.00015 21.6 0.1 0.11 12.5 0.1 2.6 2 0 0 2 2 2 2 LisH TPR_1 PF00515.28 EPE30669.1 - 1.1e-52 173.8 27.4 6.2e-08 32.1 0.1 10.6 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 EPE30669.1 - 4.9e-48 157.4 22.0 2.2e-05 24.2 0.0 10.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 EPE30669.1 - 2.2e-43 142.8 12.9 2.5e-06 27.2 0.0 10.7 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.6 EPE30669.1 - 7.4e-27 91.8 17.9 0.0022 18.2 0.2 10.5 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 EPE30669.1 - 3.2e-25 88.5 7.5 0.00018 22.1 0.7 7.0 5 2 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EPE30669.1 - 1.8e-23 81.2 7.0 0.014 16.2 0.0 8.6 5 3 4 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 EPE30669.1 - 2.9e-22 79.0 16.5 0.00019 21.9 0.2 6.8 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 EPE30669.1 - 1.2e-21 75.8 13.8 0.016 15.8 0.6 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 EPE30669.1 - 2.1e-21 75.3 27.3 4e-06 26.4 0.2 9.7 5 2 5 10 10 10 5 TPR repeat TPR_12 PF13424.6 EPE30669.1 - 3.3e-21 75.4 22.8 5.2e-05 23.5 1.0 7.7 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 EPE30669.1 - 2.2e-19 68.0 22.0 0.011 15.7 0.1 9.7 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 EPE30669.1 - 3.1e-14 52.8 11.2 0.00093 19.3 0.1 7.3 1 1 7 8 8 8 7 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE30669.1 - 5.8e-12 45.7 10.2 6.4e-08 32.7 1.5 3.8 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EPE30669.1 - 7.9e-08 31.8 15.8 0.051 12.8 0.0 5.5 2 1 2 5 5 4 4 Tetratricopeptide repeat TPR_21 PF09976.9 EPE30669.1 - 5.2e-07 29.6 5.2 0.26 11.0 0.0 4.7 3 2 1 5 5 5 3 Tetratricopeptide repeat-like domain BTAD PF03704.17 EPE30669.1 - 0.0011 19.4 3.7 4.2 7.8 0.1 3.6 3 0 0 3 3 3 2 Bacterial transcriptional activator domain TPR_MalT PF17874.1 EPE30669.1 - 0.0013 18.2 3.8 0.31 10.3 0.2 3.3 2 1 1 3 3 3 1 MalT-like TPR region TPR_20 PF14561.6 EPE30669.1 - 0.002 18.4 2.6 2.6 8.4 0.0 4.2 4 1 1 5 5 4 1 Tetratricopeptide repeat DUF2225 PF09986.9 EPE30669.1 - 0.0099 15.6 2.9 0.56 9.9 0.1 3.2 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.6 EPE30669.1 - 0.074 12.5 13.5 3.2 7.1 1.8 4.6 1 1 4 5 5 5 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 EPE30669.1 - 8 6.5 23.8 10 6.1 0.0 7.4 9 0 0 9 9 9 0 Tetratricopeptide repeat Ribosomal_L3 PF00297.22 EPE30670.1 - 4.5e-183 608.3 10.7 5.1e-183 608.1 10.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 NuiA PF07924.11 EPE30671.1 - 0.00017 22.0 0.0 0.082 13.3 0.0 2.5 1 1 0 1 1 1 1 Nuclease A inhibitor-like protein DUF1296 PF06972.11 EPE30671.1 - 0.91 9.7 4.3 15 5.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) Alpha-L-AF_C PF06964.12 EPE30672.1 - 3.2e-29 102.2 0.0 5.1e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_79n PF03662.14 EPE30672.1 - 0.019 13.9 0.3 0.4 9.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 79, N-terminal domain Sugar_tr PF00083.24 EPE30673.1 - 1e-102 344.3 20.1 1.2e-102 344.2 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE30673.1 - 3.8e-26 91.9 27.0 3.9e-20 72.1 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2838 PF10998.8 EPE30673.1 - 6.6 7.0 8.3 3.3 8.0 2.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2838) APH PF01636.23 EPE30674.1 - 6.4e-10 39.4 0.0 2.3e-09 37.6 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EPE30674.1 - 0.00013 21.0 0.0 0.044 12.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) RIO1 PF01163.22 EPE30674.1 - 0.037 13.6 0.1 7.5 6.1 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Fructosamin_kin PF03881.14 EPE30674.1 - 0.085 12.0 0.0 8.9 5.4 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase Sugar_tr PF00083.24 EPE30675.1 - 2.6e-109 366.1 23.6 3.2e-109 365.8 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE30675.1 - 1.8e-17 63.3 41.6 7.4e-15 54.7 10.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EPE30675.1 - 0.00032 19.1 3.5 0.00032 19.1 3.5 2.0 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family zf-CCHC PF00098.23 EPE30676.1 - 3.7e-45 150.1 82.2 1.8e-06 27.8 1.7 10.4 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_4 PF14392.6 EPE30676.1 - 1.1e-08 34.6 59.5 0.15 11.8 0.5 10.2 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.6 EPE30676.1 - 1.4e-06 28.0 71.6 0.0057 16.5 1.1 10.1 10 0 0 10 10 10 7 Zinc knuckle zf-CCHC_6 PF15288.6 EPE30676.1 - 0.084 12.7 0.3 0.084 12.7 0.3 9.5 8 2 1 9 9 9 0 Zinc knuckle RhlB PF12300.8 EPE30676.1 - 1.2 9.3 13.3 0.049 13.8 3.7 2.6 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB Aldo_ket_red PF00248.21 EPE30677.1 - 3.1e-63 213.7 0.0 3.6e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_ABA_S PF18066.1 EPE30677.1 - 0.072 13.8 0.5 0.53 11.0 0.0 2.5 2 1 1 3 3 3 0 Phage ABA sandwich domain Gram_pos_anchor PF00746.21 EPE30678.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Cytochrom_B558a PF05038.13 EPE30678.1 - 0.038 13.6 0.1 0.073 12.6 0.1 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit ABC2_membrane_2 PF12679.7 EPE30678.1 - 0.038 13.3 0.2 0.05 12.9 0.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein BatD PF13584.6 EPE30678.1 - 0.066 12.0 0.1 0.086 11.6 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance Phage_holin_3_6 PF07332.11 EPE30678.1 - 0.095 12.7 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Tfb5 PF06331.12 EPE30679.1 - 6.2e-23 80.6 1.2 6.8e-23 80.4 1.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Ribosomal_L16 PF00252.18 EPE30680.1 - 6.2e-31 107.1 0.3 1.2e-30 106.3 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L16p/L10e MliC PF09864.9 EPE30680.1 - 0.0026 17.7 0.1 0.0057 16.6 0.1 1.6 1 0 0 1 1 1 1 Membrane-bound lysozyme-inhibitor of c-type lysozyme RFC1 PF08519.12 EPE30681.1 - 1.3e-57 194.4 0.2 4.2e-57 192.7 0.0 2.0 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EPE30681.1 - 8.5e-12 45.3 0.0 2.3e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EPE30681.1 - 1.8e-09 38.1 0.2 3.6e-08 33.9 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EPE30681.1 - 1.4e-06 28.3 0.0 4.1e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 EPE30681.1 - 0.0002 21.6 0.1 0.013 15.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPE30681.1 - 0.0027 18.0 0.0 0.019 15.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPE30681.1 - 0.0049 17.3 0.0 0.023 15.1 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EPE30681.1 - 0.006 17.1 0.5 0.042 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EPE30681.1 - 0.017 14.8 0.1 0.19 11.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain DNA_pol3_delta PF06144.13 EPE30681.1 - 0.039 13.7 0.2 0.29 10.9 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase III, delta subunit RuvB_N PF05496.12 EPE30681.1 - 0.049 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EPE30681.1 - 0.07 13.2 0.0 0.24 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EPE30681.1 - 0.07 13.5 0.1 0.64 10.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 EPE30681.1 - 0.088 13.1 1.9 0.33 11.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EPE30681.1 - 0.094 12.7 0.0 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DDE_Tnp_IS66 PF03050.14 EPE30681.1 - 0.32 10.4 2.2 12 5.2 0.0 2.8 2 0 0 2 2 2 0 Transposase IS66 family VEFS-Box PF09733.9 EPE30681.1 - 0.94 9.3 3.5 1.2 9.0 0.1 2.8 2 0 0 2 2 2 0 VEFS-Box of polycomb protein WD40 PF00400.32 EPE30682.1 - 9.7e-45 149.7 25.5 1.1e-08 35.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE30682.1 - 6.1e-09 36.1 0.4 0.11 12.9 0.0 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPE30682.1 - 0.00011 21.0 4.9 0.039 12.6 0.1 4.1 1 1 4 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EPE30682.1 - 0.006 15.6 0.1 9.6 5.1 0.0 3.8 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EPE30682.1 - 0.0071 15.7 0.0 0.72 9.1 0.0 2.6 2 1 0 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 EPE30682.1 - 0.013 14.1 0.1 3 6.3 0.2 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 EPE30682.1 - 0.023 14.6 0.9 22 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat VID27 PF08553.10 EPE30682.1 - 0.16 11.0 0.0 0.49 9.4 0.0 1.8 2 1 0 2 2 2 0 VID27 C-terminal WD40-like domain FAD_binding_8 PF08022.12 EPE30683.1 - 1e-20 73.9 0.0 2.9e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EPE30683.1 - 2.2e-15 57.1 0.0 5.1e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EPE30683.1 - 1.9e-10 41.0 8.0 1.9e-10 41.0 8.0 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_1 PF00036.32 EPE30683.1 - 0.001 18.5 0.4 0.0022 17.4 0.4 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EPE30683.1 - 0.0033 17.8 0.4 0.0067 16.9 0.4 1.5 1 0 0 1 1 1 1 EF-hand domain pair DUF4856 PF16148.5 EPE30683.1 - 0.019 14.0 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4856) EF-hand_6 PF13405.6 EPE30683.1 - 0.025 14.5 0.4 0.067 13.2 0.4 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 EPE30683.1 - 0.2 11.2 0.1 0.46 10.1 0.1 1.7 1 0 0 1 1 1 0 EF hand DUF308 PF03729.13 EPE30683.1 - 0.95 9.8 6.8 0.086 13.2 1.0 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) GFA PF04828.14 EPE30684.1 - 1.3e-16 60.7 7.3 3e-11 43.5 0.3 2.5 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme EMP24_GP25L PF01105.24 EPE30685.1 - 2e-43 148.4 0.0 2.3e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 EPE30685.1 - 0.011 14.0 0.4 0.014 13.6 0.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA NPV_P10 PF05531.12 EPE30686.1 - 0.11 12.9 2.7 89 3.7 0.0 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein ArAE_2_N PF10337.9 EPE30688.1 - 7e-25 88.0 16.9 7e-25 88.0 16.9 4.0 2 2 1 3 3 3 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EPE30688.1 - 5.7e-11 42.6 16.8 5.7e-11 42.6 16.8 3.4 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EPE30688.1 - 0.0041 17.0 0.0 0.053 13.3 0.0 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 RhlB PF12300.8 EPE30689.1 - 0.02 15.1 12.9 0.02 15.1 12.9 1.4 1 1 0 1 1 1 0 ATP-dependent RNA helicase RhlB Het-C PF07217.11 EPE30691.1 - 3e-239 795.2 0.0 3.7e-239 795.0 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C NAD_binding_1 PF00175.21 EPE30692.1 - 1.9e-32 112.2 0.0 5.2e-32 110.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EPE30692.1 - 4.3e-25 87.9 0.0 7.6e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EPE30692.1 - 4.7e-08 33.3 0.0 0.00031 20.9 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Acetyltransf_10 PF13673.7 EPE30693.1 - 1.4e-09 37.9 0.0 7.2e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE30693.1 - 1.4e-07 31.7 0.0 7.4e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE30693.1 - 1.2e-05 25.6 0.0 8.3e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPE30693.1 - 0.0039 17.3 0.0 0.0072 16.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Peroxidase_2 PF01328.17 EPE30694.1 - 1.3e-49 169.3 0.1 1.7e-49 168.9 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 DUF2237 PF09996.9 EPE30695.1 - 1.6e-42 144.1 0.1 2.1e-42 143.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) ELL PF10390.9 EPE30696.1 - 0.0029 17.2 0.0 0.0029 17.2 0.0 2.7 2 1 0 2 2 2 1 RNA polymerase II elongation factor ELL Dynein_light PF01221.18 EPE30697.1 - 8.7e-40 134.9 1.1 9.9e-40 134.8 1.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_M24 PF00557.24 EPE30697.1 - 0.0067 16.1 0.0 0.0076 16.0 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 RRM_1 PF00076.22 EPE30698.1 - 3e-77 254.4 0.2 1.4e-18 66.4 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPE30698.1 - 4.6e-08 32.8 0.0 0.00098 18.9 0.0 4.2 5 0 0 5 5 5 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EPE30698.1 - 4.3e-06 26.8 0.0 1.8 8.7 0.0 5.0 5 0 0 5 5 5 1 RNA recognition motif Limkain-b1 PF11608.8 EPE30698.1 - 7e-06 26.0 0.1 3.8 7.7 0.0 5.6 6 1 0 6 6 6 2 Limkain b1 RRM_3 PF08777.11 EPE30698.1 - 3.4e-05 23.8 0.8 0.75 9.9 0.0 4.4 3 1 1 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.6 EPE30698.1 - 0.00017 21.5 0.0 3.8 7.6 0.0 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EPE30698.1 - 0.0015 18.1 0.0 1.1 8.9 0.0 3.8 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EPE30698.1 - 0.0052 16.6 0.2 54 3.5 0.1 4.8 5 0 0 5 5 5 0 Rrp7 RRM-like N-terminal domain TEA PF01285.18 EPE30699.1 - 6.1e-25 87.1 0.0 1.3e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 TEA/ATTS domain CinA PF02464.17 EPE30701.1 - 1.7e-26 92.6 1.7 6.5e-26 90.8 0.2 2.0 2 0 0 2 2 2 1 Competence-damaged protein SSF PF00474.17 EPE30703.1 - 1.5e-17 63.6 33.8 3.6e-17 62.3 33.8 1.6 1 1 0 1 1 1 1 Sodium:solute symporter family zinc_ribbon_15 PF17032.5 EPE30704.1 - 2.9e-05 24.7 1.0 4.7e-05 24.1 1.0 1.3 1 0 0 1 1 1 1 zinc-ribbon family RecR PF02132.15 EPE30704.1 - 0.0039 16.7 1.7 0.089 12.4 0.2 2.2 2 0 0 2 2 2 1 RecR protein DUF2769 PF10967.8 EPE30704.1 - 0.0049 17.5 0.8 0.0076 16.9 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2769) DUF5465 PF17553.2 EPE30704.1 - 0.14 12.7 1.1 89 4.1 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5465) Melibiase_2 PF16499.5 EPE30705.1 - 8.1e-59 199.1 0.8 1.4e-58 198.4 0.8 1.4 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EPE30705.1 - 3.6e-15 55.8 0.0 8.4e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EPE30705.1 - 2.8e-06 26.5 0.0 4.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Melibiase Raffinose_syn PF05691.12 EPE30705.1 - 0.021 12.6 0.1 0.027 12.3 0.1 1.2 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Acetyltransf_1 PF00583.25 EPE30706.1 - 1.5e-14 54.2 0.1 2.1e-14 53.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE30706.1 - 2.5e-12 47.0 0.5 3.8e-12 46.4 0.5 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPE30706.1 - 4e-11 42.9 0.0 6.1e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EPE30706.1 - 0.00035 21.2 0.0 0.00046 20.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE30706.1 - 0.00091 19.1 0.1 0.003 17.5 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Rubredoxin_C PF18267.1 EPE30706.1 - 0.06 13.3 0.1 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Rubredoxin NAD+ reductase C-terminal domain DUF3887 PF13026.6 EPE30706.1 - 0.091 13.6 0.2 0.16 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) Acetyltransf_CG PF14542.6 EPE30706.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Sugar_tr PF00083.24 EPE30707.1 - 4.1e-80 269.8 23.7 4.7e-80 269.6 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE30707.1 - 2.5e-15 56.3 37.7 9.8e-12 44.5 30.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily EBP PF05241.12 EPE30707.1 - 7.5 6.0 11.3 0.32 10.4 1.4 3.1 2 2 1 3 3 3 0 Emopamil binding protein FA_desaturase PF00487.24 EPE30708.1 - 2.9e-11 43.7 22.2 2.9e-11 43.7 22.2 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Pribosyltran PF00156.27 EPE30710.1 - 1.5e-16 60.3 0.0 2.1e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EPE30710.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase WD40 PF00400.32 EPE30711.1 - 2.4e-13 50.3 11.6 0.011 16.5 0.0 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE30711.1 - 1e-06 28.9 0.1 0.28 11.5 0.0 5.2 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EPE30711.1 - 2.1e-05 24.0 0.0 0.00063 19.2 0.0 2.6 3 0 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 EPE30711.1 - 0.00032 19.5 0.3 0.11 11.1 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 FliO PF04347.13 EPE30711.1 - 0.013 15.8 0.0 1.2 9.5 0.0 2.3 1 1 1 2 2 2 0 Flagellar biosynthesis protein, FliO DUF1852 PF08908.11 EPE30711.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1852) Atg14 PF10186.9 EPE30712.1 - 9.6e-15 54.5 10.8 3.2e-13 49.5 10.8 2.1 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 EPE30712.1 - 1.4e-09 37.4 6.6 0.0045 15.9 1.4 3.5 3 1 0 3 3 3 3 Vacuolar protein sorting 38 APG6 PF04111.12 EPE30712.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Apg6 BARA domain vWF_A PF12450.8 EPE30712.1 - 0.14 12.1 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor XFP_N PF09364.10 EPE30713.1 - 5.1e-175 581.6 0.0 6.6e-175 581.2 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 EPE30713.1 - 6.5e-84 280.4 0.0 9.2e-84 279.9 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 EPE30713.1 - 3e-80 268.1 0.0 4.5e-80 267.5 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Enolase_like_N PF18374.1 EPE30714.1 - 0.83 9.1 2.1 1.1 8.7 0.5 1.9 2 0 0 2 2 2 0 Enolase N-terminal domain-like NACHT PF05729.12 EPE30716.1 - 1.3e-09 38.2 0.0 2.6e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EPE30716.1 - 4.7e-06 27.1 0.2 2.9e-05 24.5 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain DUF2075 PF09848.9 EPE30716.1 - 0.002 17.4 0.1 0.022 14.0 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EPE30716.1 - 0.0028 18.0 0.0 0.012 15.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain Ank_2 PF12796.7 EPE30716.1 - 0.0033 18.0 0.0 0.011 16.3 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE30716.1 - 0.0083 16.7 0.0 0.057 14.0 0.0 2.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) AAA PF00004.29 EPE30716.1 - 0.012 16.1 0.0 0.032 14.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EPE30716.1 - 0.065 13.6 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase KIP1 PF07765.12 EPE30716.1 - 0.065 13.4 0.8 0.57 10.3 0.1 2.9 2 0 0 2 2 2 0 KIP1-like protein Clathrin PF00637.20 EPE30716.1 - 0.16 11.9 0.4 2.6 7.9 0.0 2.8 3 0 0 3 3 3 0 Region in Clathrin and VPS SNF2_N PF00176.23 EPE30717.1 - 6.8e-63 212.5 0.0 9.9e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE30717.1 - 4.2e-08 33.5 0.0 5.4e-07 29.9 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE30717.1 - 4.7e-05 23.5 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EPE30717.1 - 4.9e-05 23.2 0.0 0.00017 21.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 EPE30717.1 - 0.08 12.8 8.7 0.21 11.5 8.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EPE30717.1 - 0.088 12.8 13.5 0.22 11.5 13.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EPE30717.1 - 1.1 9.2 14.3 5.9 6.8 14.5 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE30717.1 - 2.2 8.2 14.2 6.1 6.8 14.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE30717.1 - 7.6 7.0 12.7 26 5.2 12.7 2.0 1 0 0 1 1 1 0 Ring finger domain CGI-121 PF08617.10 EPE30720.1 - 3.9e-54 183.1 0.0 4.6e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Fungal_trans PF04082.18 EPE30721.1 - 1.4e-11 44.0 2.0 2.2e-11 43.3 2.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE30721.1 - 1.3e-06 28.4 8.0 2.5e-06 27.5 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLDc_3 PF13918.6 EPE30722.1 - 0.11 12.2 0.1 2.4 7.8 0.0 2.1 2 0 0 2 2 2 0 PLD-like domain APC_15aa PF05972.11 EPE30722.1 - 8.1 6.9 5.2 51 4.4 0.3 2.3 2 0 0 2 2 2 0 APC 15 residue motif Ank_2 PF12796.7 EPE30724.1 - 1.5e-42 144.0 1.8 3e-13 50.1 0.3 4.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EPE30724.1 - 3e-33 112.8 11.0 0.00026 21.3 0.2 9.6 10 0 0 10 10 9 6 Ankyrin repeat Ank_3 PF13606.6 EPE30724.1 - 1.2e-31 105.2 7.2 0.00034 20.8 0.0 9.6 10 0 0 10 10 10 6 Ankyrin repeat Ank_4 PF13637.6 EPE30724.1 - 3.6e-31 107.1 11.3 8.3e-10 39.0 0.1 7.4 3 2 5 8 8 8 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE30724.1 - 8.2e-27 92.9 3.5 1.5e-09 37.9 0.3 5.4 3 2 1 4 4 4 3 Ankyrin repeats (many copies) CorA PF01544.18 EPE30724.1 - 7.7e-11 41.8 1.3 1.6e-10 40.8 0.7 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 EPE30724.1 - 0.0023 16.8 0.4 0.0038 16.1 0.4 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) LXG PF04740.12 EPE30724.1 - 0.052 13.3 6.4 0.11 12.2 6.4 1.5 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF1676 PF07898.13 EPE30724.1 - 0.069 13.2 1.2 0.17 12.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) DUF1198 PF06711.11 EPE30724.1 - 0.13 12.3 2.1 11 6.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) DASH_Dad2 PF08654.10 EPE30724.1 - 0.45 11.0 3.6 0.45 11.0 0.5 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad2 PRP1_N PF06424.12 EPE30724.1 - 3.3 8.1 10.7 0.086 13.2 3.1 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal FAM76 PF16046.5 EPE30724.1 - 9.4 5.5 14.5 0.16 11.3 2.1 2.3 2 0 0 2 2 2 0 FAM76 protein Esterase_phd PF10503.9 EPE30725.1 - 2e-21 76.5 0.3 2.8e-21 76.1 0.3 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EPE30725.1 - 2.1e-05 24.1 0.5 3.5e-05 23.4 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EPE30725.1 - 0.0011 18.7 0.2 0.0037 16.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EPE30725.1 - 0.014 15.2 0.9 0.027 14.3 0.1 1.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 EPE30725.1 - 0.12 12.2 0.6 0.2 11.5 0.6 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2920 PF11144.8 EPE30725.1 - 0.16 11.1 0.7 0.28 10.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) CarS-like PF01864.17 EPE30725.1 - 0.19 11.7 0.2 0.29 11.1 0.2 1.2 1 0 0 1 1 1 0 CDP-archaeol synthase Glyco_hydro_61 PF03443.14 EPE30726.1 - 7.2e-47 160.0 0.3 8.2e-47 159.8 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ricin_B_lectin PF00652.22 EPE30727.1 - 1.2e-10 41.7 0.2 1e-09 38.7 0.2 1.9 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EPE30727.1 - 6.6e-07 30.0 0.6 3.8e-05 24.3 0.4 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like WSC PF01822.19 EPE30728.1 - 1.6e-61 204.5 63.7 7.4e-19 67.7 13.7 5.2 4 1 0 4 4 4 4 WSC domain DUF1929 PF09118.11 EPE30728.1 - 1.2e-22 80.0 0.1 3.9e-22 78.4 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 EPE30728.1 - 1.7e-19 69.9 0.0 3.9e-18 65.5 0.0 2.6 2 1 1 3 3 3 2 Glyoxal oxidase N-terminus Glyco_transf_28 PF03033.20 EPE30729.1 - 1.5e-18 67.2 0.7 9.6e-12 45.1 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EPE30729.1 - 4.5e-06 25.7 0.1 7.4e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 EPE30729.1 - 4.6e-05 23.7 0.0 0.0003 21.1 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 EPE30729.1 - 0.0015 18.5 0.0 0.0044 17.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UIM PF02809.20 EPE30729.1 - 0.32 11.0 20.1 0.28 11.2 1.1 5.3 4 0 0 4 4 4 0 Ubiquitin interaction motif Cutinase PF01083.22 EPE30730.1 - 4.8e-49 166.7 1.3 5.5e-49 166.5 1.3 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EPE30730.1 - 3.1e-05 23.6 0.3 3.9e-05 23.3 0.3 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.8 EPE30730.1 - 0.00051 19.7 0.1 0.00071 19.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 EPE30730.1 - 0.0077 16.1 0.1 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 EPE30730.1 - 0.019 15.1 0.1 0.028 14.5 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 EPE30730.1 - 0.03 14.2 0.4 0.045 13.6 0.4 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EPE30730.1 - 0.064 12.9 0.1 0.075 12.7 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold VirJ PF06057.11 EPE30730.1 - 0.075 12.9 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) vATP-synt_E PF01991.18 EPE30730.1 - 0.24 10.8 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Phasin_2 PF09361.10 EPE30731.1 - 0.055 13.7 0.0 0.71 10.2 0.0 2.3 1 1 1 2 2 2 0 Phasin protein MgtE_N PF03448.17 EPE30731.1 - 8.7 7.0 22.2 1.9 9.2 5.9 3.9 2 1 0 3 3 3 0 MgtE intracellular N domain APH PF01636.23 EPE30732.1 - 2.4e-10 40.7 0.0 7.8e-09 35.8 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family CDC45 PF02724.14 EPE30734.1 - 0.0093 14.3 0.2 0.013 13.9 0.2 1.1 1 0 0 1 1 1 1 CDC45-like protein Sporozoite_P67 PF05642.11 EPE30734.1 - 0.035 12.2 0.0 0.049 11.7 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.6 EPE30734.1 - 0.072 13.5 4.3 0.13 12.6 4.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GET2 PF08690.10 EPE30734.1 - 0.085 12.5 1.9 0.13 11.9 1.9 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 RRN3 PF05327.11 EPE30734.1 - 0.087 11.4 0.6 0.12 10.9 0.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Fungal_trans PF04082.18 EPE30735.1 - 2.3e-23 82.6 0.2 3.9e-23 81.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE30735.1 - 1.1e-09 38.2 11.4 1.9e-09 37.5 11.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3-WW_linker PF16618.5 EPE30735.1 - 0.026 15.0 0.2 0.22 12.0 0.0 2.5 2 0 0 2 2 2 0 Linker region between SH3 and WW domains on ARHGAP12 Plectin PF00681.20 EPE30735.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Plectin repeat Ephrin_rec_like PF07699.13 EPE30736.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 Putative ephrin-receptor like Bax1-I PF01027.20 EPE30737.1 - 4e-38 131.3 11.8 7.5e-38 130.4 11.8 1.4 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PMSR PF01625.21 EPE30738.1 - 1.6e-63 213.4 0.6 1.9e-63 213.2 0.6 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase SH3_1 PF00018.28 EPE30738.1 - 4.2 7.1 7.3 3 7.5 0.9 2.3 1 1 1 2 2 2 0 SH3 domain Kinesin PF00225.23 EPE30740.1 - 2.5e-116 388.2 0.3 5.6e-116 387.1 0.0 1.8 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EPE30740.1 - 5e-28 97.9 0.2 1.8e-27 96.1 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding AAA_33 PF13671.6 EPE30740.1 - 0.0045 17.2 0.0 0.022 14.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain TAP42 PF04177.12 EPE30740.1 - 0.96 8.5 8.0 2.6 7.1 8.0 1.8 1 1 0 1 1 1 0 TAP42-like family DUF4795 PF16043.5 EPE30740.1 - 1.5 8.4 6.7 0.57 9.8 3.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Aldedh PF00171.22 EPE30741.1 - 2.4e-154 514.3 0.0 2.7e-154 514.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EPE30741.1 - 4.2e-05 22.8 0.0 6.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 EPE30741.1 - 0.0031 17.0 0.0 0.011 15.2 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) FRD2 PF03197.13 EPE30741.1 - 0.15 12.4 0.0 0.4 11.0 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage FRD2 protein SnoaL_4 PF13577.6 EPE30742.1 - 4.1e-28 98.0 0.3 6.5e-28 97.4 0.3 1.3 1 0 0 1 1 1 1 SnoaL-like domain Amidohydro_2 PF04909.14 EPE30743.1 - 2.6e-36 125.9 0.0 3.9e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase RPE65 PF03055.15 EPE30744.1 - 1.6e-102 344.1 0.0 2e-102 343.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Sigma_reg_N PF13800.6 EPE30745.1 - 0.09 13.1 0.2 1.8 8.9 0.0 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Epiglycanin_C PF14654.6 EPE30745.1 - 0.16 12.0 0.6 0.91 9.6 0.2 2.2 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Receptor_2B4 PF11465.8 EPE30745.1 - 0.17 12.1 0.6 0.34 11.1 0.1 1.7 2 0 0 2 2 2 0 Natural killer cell receptor 2B4 Syndecan PF01034.20 EPE30745.1 - 0.25 11.3 0.4 0.55 10.2 0.4 1.5 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 EPE30745.1 - 0.4 10.6 0.0 0.4 10.6 0.0 2.1 3 0 0 3 3 3 0 TMEM154 protein family DUF1122 PF06557.11 EPE30746.1 - 0.039 13.4 0.2 0.073 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) Cmc1 PF08583.10 EPE30747.1 - 7.3e-12 45.1 0.9 7.3e-12 45.1 0.9 2.7 1 1 2 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like Utp11 PF03998.13 EPE30748.1 - 3.8e-63 213.7 23.3 4.3e-63 213.5 23.3 1.0 1 0 0 1 1 1 1 Utp11 protein HemY_N PF07219.13 EPE30749.1 - 0.17 12.1 0.1 0.38 11.0 0.1 1.5 1 0 0 1 1 1 0 HemY protein N-terminus G_glu_transpept PF01019.21 EPE30750.1 - 2.8e-149 498.2 0.1 3.3e-149 498.0 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase GTA_holin_3TM PF11351.8 EPE30751.1 - 0.055 14.0 0.0 0.27 11.8 0.0 2.1 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release DUF3844 PF12955.7 EPE30752.1 - 5.9e-31 106.7 2.6 1.1e-30 105.8 2.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) PAF-AH_p_II PF03403.13 EPE30753.1 - 8.5e-56 189.1 0.0 1.5e-52 178.4 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EPE30753.1 - 9.3e-06 24.7 0.1 5.5e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EPE30753.1 - 0.0025 16.9 0.0 0.0049 15.9 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 EPE30753.1 - 0.0026 17.0 0.0 1.7 7.9 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Aldo_ket_red PF00248.21 EPE30756.1 - 3.7e-38 131.4 0.0 5.9e-38 130.7 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.7 EPE30757.1 - 3.6e-36 122.6 27.2 2.6e-08 34.0 1.5 6.5 4 1 5 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EPE30757.1 - 7.4e-24 83.3 22.8 4.7e-07 29.5 1.4 5.7 3 2 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 EPE30757.1 - 2e-18 66.5 28.8 1.6e-08 34.3 1.9 3.6 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 EPE30757.1 - 6.7e-07 28.9 22.2 0.1 12.7 0.5 8.0 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.33 EPE30757.1 - 0.00059 20.0 22.5 9.2 7.3 0.0 8.3 8 1 0 8 8 8 3 Leucine Rich Repeat Hydrolase_4 PF12146.8 EPE30758.1 - 0.0036 16.6 0.0 0.17 11.1 0.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 MiAMP1 PF09117.10 EPE30759.1 - 0.00074 19.7 1.1 0.0011 19.2 1.1 1.3 1 0 0 1 1 1 1 MiAMP1 SnoaL_2 PF12680.7 EPE30760.1 - 3.9e-09 37.1 0.0 4.7e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain BTB PF00651.31 EPE30761.1 - 6.5e-09 36.0 0.0 2.6e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain PCI PF01399.27 EPE30762.1 - 9.1e-10 39.0 0.0 3e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 PCI domain Ribosomal_L18A PF01775.17 EPE30763.1 - 1.7e-54 183.1 0.5 2.1e-54 182.8 0.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DNA_pol_A_exo1 PF01612.20 EPE30764.1 - 0.0082 15.9 0.0 0.18 11.5 0.0 2.1 1 1 1 2 2 2 2 3'-5' exonuclease Radical_SAM PF04055.21 EPE30764.1 - 0.057 13.8 0.0 0.089 13.2 0.0 1.3 1 0 0 1 1 1 0 Radical SAM superfamily SAD_SRA PF02182.17 EPE30765.1 - 7.1e-27 94.0 0.0 1.2e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain Calycin_like PF13944.6 EPE30767.1 - 0.019 15.3 3.3 0.029 14.7 3.3 1.4 1 1 0 1 1 1 0 Calycin-like beta-barrel domain Queuosine_synth PF02547.15 EPE30767.1 - 0.12 11.5 1.4 0.14 11.2 1.4 1.1 1 0 0 1 1 1 0 Queuosine biosynthesis protein MFS_1 PF07690.16 EPE30769.1 - 1.8e-29 102.8 46.9 1.8e-29 102.8 46.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily HTH_17 PF12728.7 EPE30770.1 - 0.063 13.5 0.1 0.3 11.3 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Peptidase_M19 PF01244.21 EPE30771.1 - 2.1e-95 319.6 0.1 2.4e-95 319.4 0.1 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Methyltransf_23 PF13489.6 EPE30772.1 - 5.2e-09 36.2 0.0 6.7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE30772.1 - 1.9e-05 25.3 0.0 3.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE30772.1 - 0.00026 20.8 0.0 0.00052 19.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE30772.1 - 0.00064 20.4 0.0 0.0012 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EPE30772.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_23 PF13489.6 EPE30773.1 - 1.4e-08 34.8 0.0 1.9e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE30773.1 - 2.2e-08 34.7 0.0 4.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE30773.1 - 5.5e-05 23.0 0.0 8.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE30773.1 - 0.0001 22.9 0.0 0.00017 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EPE30773.1 - 0.0043 16.6 0.0 0.019 14.5 0.0 1.9 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 EPE30773.1 - 0.0073 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_PK PF05891.12 EPE30773.1 - 0.013 15.0 0.0 0.035 13.6 0.0 1.7 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 EPE30773.1 - 0.042 13.1 0.1 0.077 12.3 0.1 1.4 1 1 0 1 1 1 0 O-methyltransferase domain MucBP PF06458.12 EPE30775.1 - 0.013 16.5 0.0 0.017 16.1 0.0 1.3 1 0 0 1 1 1 0 MucBP domain Aspzincin_M35 PF14521.6 EPE30776.1 - 5.1e-06 27.1 0.1 8.2e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EPE30776.1 - 0.00061 19.4 0.0 0.0018 17.9 0.1 1.6 2 0 0 2 2 2 1 Putative peptidase family DUF3652 PF12372.8 EPE30776.1 - 0.17 11.8 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Huntingtin protein region SET PF00856.28 EPE30777.1 - 1.3e-11 45.1 0.0 7.9e-11 42.6 0.0 2.1 1 1 0 1 1 1 1 SET domain Gon7 PF08738.10 EPE30777.1 - 0.063 13.4 4.2 5.2 7.2 1.2 2.6 2 1 0 2 2 2 0 Gon7 family HTH_Tnp_1 PF01527.20 EPE30779.1 - 0.12 12.7 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 Transposase NIF PF03031.18 EPE30780.1 - 2.7e-53 179.9 0.1 4e-53 179.4 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sec61_beta PF03911.16 EPE30780.1 - 9.9e-18 63.9 2.6 1.8e-17 63.1 2.6 1.5 1 0 0 1 1 1 1 Sec61beta family ABC_membrane_2 PF06472.15 EPE30782.1 - 9.5e-92 307.2 0.1 9.5e-92 307.2 0.1 1.9 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EPE30782.1 - 2.4e-15 57.3 0.0 6.8e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 EPE30782.1 - 0.0026 18.3 1.3 0.02 15.4 1.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EPE30782.1 - 0.016 15.0 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EPE30782.1 - 0.056 13.2 0.0 0.23 11.2 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EPE30782.1 - 0.064 13.6 0.1 0.22 11.9 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 EPE30782.1 - 0.09 12.2 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EPE30782.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Glyco_hydro_72 PF03198.14 EPE30783.1 - 1.7e-117 392.2 0.2 2.2e-117 391.8 0.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EPE30783.1 - 7.5e-18 65.0 2.2 2.6e-17 63.3 2.2 2.0 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 EPE30783.1 - 0.08 12.0 0.1 0.3 10.2 0.1 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Pectinesterase PF01095.19 EPE30784.1 - 3.4e-31 108.1 0.6 9.7e-26 90.2 1.1 2.1 1 1 0 2 2 2 2 Pectinesterase Chlorosome_CsmC PF11098.8 EPE30785.1 - 0.0019 18.2 9.0 0.0023 17.9 9.0 1.0 1 0 0 1 1 1 1 Chlorosome envelope protein C Perilipin PF03036.16 EPE30785.1 - 0.3 10.1 0.2 0.32 10.0 0.2 1.0 1 0 0 1 1 1 0 Perilipin family PT-VENN PF04829.13 EPE30785.1 - 2.8 8.1 0.0 2.8 8.1 0.0 4.2 2 1 0 2 2 2 0 Pre-toxin domain with VENN motif Endostatin PF06482.11 EPE30787.1 - 0.0024 17.4 11.0 0.0029 17.1 11.0 1.1 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin eIF-3_zeta PF05091.12 EPE30787.1 - 0.54 9.2 17.9 0.68 8.8 17.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GET2 PF08690.10 EPE30787.1 - 0.83 9.3 15.4 0.94 9.1 15.4 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 TFIIA PF03153.13 EPE30787.1 - 1.7 8.5 25.2 2 8.4 25.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Membralin PF09746.9 EPE30787.1 - 3.2 6.7 6.7 3.2 6.7 6.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein PAT1 PF09770.9 EPE30787.1 - 3.3 5.9 20.7 3.5 5.8 20.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 EPE30787.1 - 4.6 6.7 20.7 5.1 6.6 20.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CPSF100_C PF13299.6 EPE30787.1 - 6.5 6.9 8.9 8.1 6.6 8.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MDM10 PF12519.8 EPE30787.1 - 8.2 5.2 12.1 9.8 4.9 12.1 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Abhydrolase_6 PF12697.7 EPE30790.1 - 0.00078 20.1 0.2 0.0014 19.2 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EPE30790.1 - 0.0049 16.6 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 EPE30790.1 - 0.0073 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 EPE30790.1 - 0.0074 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 EPE30790.1 - 0.17 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF3659 PF12396.8 EPE30791.1 - 2e-14 53.2 9.4 5.5e-14 51.8 9.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3659) Apolipoprotein PF01442.18 EPE30791.1 - 1.2e-05 25.2 6.6 1.2e-05 25.2 6.6 3.7 3 2 0 3 3 3 2 Apolipoprotein A1/A4/E domain DUF842 PF05811.13 EPE30791.1 - 0.12 12.1 5.3 0.91 9.2 0.5 3.6 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) MT0933_antitox PF14013.6 EPE30791.1 - 0.25 11.7 0.0 0.25 11.7 0.0 12.4 4 4 5 9 9 9 0 MT0933-like antitoxin protein DUF3659 PF12396.8 EPE30792.1 - 5.5e-178 577.1 104.0 5.3e-24 83.9 2.0 10.7 11 0 0 11 11 11 10 Protein of unknown function (DUF3659) Trypan_PARP PF05887.11 EPE30792.1 - 0.0018 18.2 10.0 0.0018 18.2 10.0 7.9 7 2 2 9 9 9 1 Procyclic acidic repetitive protein (PARP) 2C_adapt PF08793.10 EPE30792.1 - 0.031 14.5 0.0 0.11 12.7 0.0 2.0 1 0 0 1 1 1 0 2-cysteine adaptor domain BPL_C PF02237.17 EPE30792.1 - 0.35 10.8 10.1 16 5.5 0.1 5.6 4 1 1 5 5 5 0 Biotin protein ligase C terminal domain Sugar_tr PF00083.24 EPE30793.1 - 1.9e-97 327.0 26.1 2.3e-97 326.7 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE30793.1 - 1e-31 110.1 25.8 3.2e-26 92.1 7.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EPE30793.1 - 0.0063 14.8 1.6 0.0063 14.8 1.6 3.3 2 2 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF2615 PF11027.8 EPE30793.1 - 3.4 7.8 5.3 5.6 7.2 1.4 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2615) Pectinesterase PF01095.19 EPE30794.1 - 2.5e-52 177.5 10.0 3.3e-52 177.1 10.0 1.1 1 0 0 1 1 1 1 Pectinesterase Adeno_E1B_55K PF01696.17 EPE30794.1 - 0.14 10.8 0.7 0.18 10.4 0.7 1.2 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen Histidinol_dh PF00815.20 EPE30797.1 - 6.9e-160 532.5 2.5 9.8e-160 532.0 2.5 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 EPE30797.1 - 7.2e-26 89.8 0.1 1.4e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EPE30797.1 - 3.5e-13 49.8 0.2 9.2e-13 48.5 0.2 1.8 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase TFIID-31kDa PF02291.15 EPE30798.1 - 2.3e-39 134.2 0.0 3.3e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit FAD_oxidored PF12831.7 EPE30799.1 - 0.078 12.3 0.7 0.17 11.2 0.2 1.6 1 1 1 2 2 2 0 FAD dependent oxidoreductase RNA_pol_Rpb1_1 PF04997.12 EPE30800.1 - 1.2e-108 363.1 0.0 1.8e-108 362.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EPE30800.1 - 3.6e-102 341.4 0.1 5.4e-102 340.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EPE30800.1 - 1.3e-76 256.5 0.0 2.2e-76 255.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EPE30800.1 - 1.4e-63 214.2 2.8 2.1e-63 213.6 2.8 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EPE30800.1 - 1.9e-47 161.1 0.0 4.4e-47 159.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EPE30800.1 - 2.9e-42 143.9 4.9 6.1e-42 142.8 4.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EPE30800.1 - 8.9e-38 128.6 0.1 2e-37 127.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EPE30800.1 - 8.2e-10 38.5 205.9 0.0064 16.8 6.3 14.4 13 2 2 15 15 15 12 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.32 EPE30801.1 - 2.5e-12 47.1 6.1 0.00089 20.0 0.7 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE30801.1 - 4.2e-09 36.6 1.5 0.044 14.1 0.0 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE30801.1 - 6.4e-06 26.2 0.2 0.21 11.4 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EPE30801.1 - 0.012 14.2 0.2 0.89 8.0 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Peroxidase_2 PF01328.17 EPE30802.1 - 3.7e-39 135.2 0.0 4.9e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 dCMP_cyt_deam_1 PF00383.23 EPE30804.1 - 1e-05 25.3 0.1 1.5e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Rad1 PF02144.16 EPE30805.1 - 1.4e-82 276.9 0.0 1.6e-82 276.7 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Bromodomain PF00439.25 EPE30806.1 - 4.1e-23 81.2 0.7 7.7e-23 80.4 0.7 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EPE30806.1 - 6.4e-08 32.8 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE30806.1 - 8.2e-08 32.3 0.4 6.8e-07 29.3 0.1 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE30806.1 - 0.00026 21.3 0.4 0.00063 20.1 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE30806.1 - 0.13 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein PTS_EIIC PF02378.18 EPE30807.1 - 0.0071 15.4 0.9 0.0071 15.4 0.9 1.4 2 0 0 2 2 2 1 Phosphotransferase system, EIIC DSPn PF14671.6 EPE30807.1 - 0.027 14.9 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half MR_MLE_C PF13378.6 EPE30808.1 - 1.5e-61 207.8 0.1 1.8e-61 207.5 0.1 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EPE30808.1 - 4.1e-17 62.5 0.0 8.7e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF1656 PF07869.12 EPE30810.1 - 0.46 10.5 1.6 0.83 9.7 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) CN_hydrolase PF00795.22 EPE30811.1 - 2.5e-49 168.0 0.0 2.9e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase COesterase PF00135.28 EPE30813.1 - 3e-78 263.9 0.0 3.9e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE30813.1 - 0.0025 17.7 0.0 0.018 14.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cellulase PF00150.18 EPE30815.1 - 2.1e-20 73.3 7.4 3.5e-19 69.3 7.4 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_53 PF07745.13 EPE30815.1 - 0.00047 19.2 1.4 0.00078 18.5 1.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Glyco_hydro_42 PF02449.15 EPE30815.1 - 0.033 13.5 0.6 0.18 11.1 0.0 2.2 3 0 0 3 3 3 0 Beta-galactosidase AAA PF00004.29 EPE30816.1 - 1.4e-20 74.0 0.0 7.7e-20 71.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 EPE30816.1 - 0.011 15.2 0.1 0.024 14.0 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 EPE30816.1 - 0.018 14.8 0.0 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EPE30816.1 - 0.037 14.4 0.7 0.45 10.9 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain NACHT PF05729.12 EPE30816.1 - 0.042 13.8 0.0 0.27 11.1 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_33 PF13671.6 EPE30816.1 - 0.065 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EPE30816.1 - 0.11 12.8 0.0 0.38 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EPE30816.1 - 0.17 11.6 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain 2OG-FeII_Oxy PF03171.20 EPE30817.1 - 0.0057 17.1 0.0 0.013 15.9 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FRG1 PF06229.12 EPE30818.1 - 3.5e-52 176.9 0.0 5.1e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 EPE30818.1 - 0.017 15.3 0.0 0.071 13.3 0.0 2.0 2 0 0 2 2 2 0 Fascin domain WD40 PF00400.32 EPE30819.1 - 5.8e-08 33.3 3.8 0.03 15.2 0.0 4.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EPE30819.1 - 0.0061 15.4 0.1 0.017 13.9 0.0 1.8 2 1 0 2 2 2 1 Nup133 N terminal like Cytochrom_D1 PF02239.16 EPE30819.1 - 0.034 12.7 0.0 0.25 9.8 0.0 1.9 1 1 1 2 2 2 0 Cytochrome D1 heme domain Sel1 PF08238.12 EPE30820.1 - 5.7e-24 84.0 37.8 0.00019 22.0 0.1 12.4 12 1 0 12 12 12 6 Sel1 repeat TPR_7 PF13176.6 EPE30820.1 - 0.018 15.1 1.0 2.8 8.2 0.1 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPE30820.1 - 0.056 14.3 10.0 35 5.6 0.3 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EPE30820.1 - 0.4 11.4 13.5 1 10.0 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPE30820.1 - 0.63 10.8 9.6 46 4.9 0.0 6.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 EPE30820.1 - 1.4 9.5 6.1 26 5.5 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Xan_ur_permease PF00860.20 EPE30821.1 - 3.4e-22 78.7 30.7 1.8e-21 76.3 28.0 2.8 2 1 0 2 2 2 1 Permease family TAT_signal PF10518.9 EPE30821.1 - 2 8.4 5.3 0.37 10.7 0.4 2.4 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Mei5 PF10376.9 EPE30822.1 - 6.7e-07 29.4 6.2 3.2e-05 23.9 6.2 2.6 1 1 0 1 1 1 1 Double-strand recombination repair protein DUF4597 PF15366.6 EPE30822.1 - 0.28 11.0 1.7 8.4 6.2 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) FXMRP1_C_core PF12235.8 EPE30822.1 - 2.8 8.6 10.6 4.9 7.8 10.6 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal DUF4407 PF14362.6 EPE30822.1 - 9.2 5.5 10.1 20 4.4 10.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Amidohydro_1 PF01979.20 EPE30823.1 - 4.8e-74 249.7 0.6 1.6e-73 248.0 0.6 1.8 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 EPE30823.1 - 2.5e-52 176.3 2.0 2.5e-52 176.3 2.0 1.8 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 EPE30823.1 - 2.1e-42 143.1 0.1 4.8e-42 141.9 0.1 1.6 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 EPE30823.1 - 6.7e-39 132.2 0.1 5e-38 129.4 0.1 2.2 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_3 PF07969.11 EPE30823.1 - 3.2e-10 40.1 0.5 8e-08 32.2 0.0 2.4 1 1 1 2 2 2 2 Amidohydrolase family zf-RING_2 PF13639.6 EPE30824.1 - 1.4e-10 41.4 4.6 2.7e-10 40.4 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPE30824.1 - 6.8e-08 32.2 4.5 1.8e-07 30.9 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE30824.1 - 9.9e-07 28.5 4.2 2.5e-06 27.2 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE30824.1 - 1.7e-06 27.9 3.3 3.3e-06 26.9 3.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EPE30824.1 - 3.6e-06 26.6 3.7 3.6e-06 26.6 3.7 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EPE30824.1 - 1.4e-05 25.0 6.0 5.3e-05 23.2 6.1 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EPE30824.1 - 0.00011 22.4 4.8 0.00042 20.6 4.8 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EPE30824.1 - 0.0054 16.6 5.3 0.011 15.6 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EPE30824.1 - 0.042 13.9 2.3 0.092 12.8 2.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Lyase_catalyt PF09093.11 EPE30824.1 - 0.053 12.7 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Lyase, catalytic ABC_membrane PF00664.23 EPE30824.1 - 0.17 11.5 0.0 0.64 9.6 0.1 1.7 2 0 0 2 2 2 0 ABC transporter transmembrane region Prok-RING_4 PF14447.6 EPE30824.1 - 0.36 10.7 12.1 5.3 7.0 11.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 EPE30824.1 - 0.38 10.6 4.3 1 9.3 4.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EPE30824.1 - 1.1 9.5 10.0 2.1 8.6 10.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 EPE30824.1 - 3 8.0 7.1 0.73 9.9 1.5 2.8 3 1 0 3 3 3 0 Zinc-finger zf-RING-like PF08746.11 EPE30824.1 - 3.4 8.1 4.6 6.2 7.2 3.1 2.2 2 1 0 2 2 2 0 RING-like domain Ada3 PF10198.9 EPE30825.1 - 4.7e-55 185.3 0.2 4.7e-55 185.3 0.2 2.1 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 RtcB PF01139.17 EPE30825.1 - 2.3 7.3 5.1 1.7 7.7 0.1 2.1 2 0 0 2 2 2 0 tRNA-splicing ligase RtcB Lactamase_B_2 PF12706.7 EPE30826.1 - 6.2e-06 25.9 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 EPE30826.1 - 2.4e-05 24.5 0.0 4.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 EPE30826.1 - 0.0042 17.1 0.0 0.0077 16.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EPE30826.1 - 0.062 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Glyco_tranf_2_3 PF13641.6 EPE30827.1 - 1.9e-24 86.9 0.0 2.6e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EPE30827.1 - 2.2e-08 34.1 0.0 4.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EPE30827.1 - 1.9e-06 27.5 0.0 6.6e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 DUF420 PF04238.12 EPE30827.1 - 0.0026 18.0 1.6 0.0049 17.1 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF420) DUF4870 PF09685.10 EPE30827.1 - 0.098 12.8 2.0 0.2 11.8 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) DNA_pol3_a_NII PF11490.8 EPE30829.1 - 2.2 8.2 7.5 4 7.4 7.5 1.4 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II F-box PF00646.33 EPE30830.1 - 2.8e-06 27.0 0.0 7.3e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPE30830.1 - 0.0074 16.2 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like Fungal_lectin_2 PF18647.1 EPE30832.1 - 1.1e-06 29.0 0.0 4.8e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Alpha-galactosyl-binding fungal lectin Lipase_GDSL_2 PF13472.6 EPE30832.1 - 4.2e-05 24.0 0.3 4.2e-05 24.0 0.3 1.8 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family MIOX PF05153.15 EPE30832.1 - 0.14 11.7 0.1 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 Myo-inositol oxygenase zf-C2HC_2 PF13913.6 EPE30833.1 - 8.3 6.4 7.6 7.8 6.5 2.5 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type SH3_3 PF08239.11 EPE30834.1 - 0.071 13.4 0.2 0.17 12.2 0.2 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain IncFII_repA PF02387.15 EPE30834.1 - 0.076 12.3 1.3 0.12 11.6 1.3 1.3 1 0 0 1 1 1 0 IncFII RepA protein family AC_N PF16214.5 EPE30834.1 - 0.23 10.5 1.9 0.39 9.8 1.9 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Zn_clus PF00172.18 EPE30836.1 - 4.6e-07 29.8 11.7 4.6e-07 29.8 11.7 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE30836.1 - 5.5e-07 28.7 1.3 2.2e-06 26.7 0.2 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain FliJ PF02050.16 EPE30836.1 - 0.03 14.6 4.4 0.038 14.2 2.0 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein MIT PF04212.18 EPE30836.1 - 0.14 12.3 0.3 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Myf5 PF12232.8 EPE30836.1 - 0.34 11.7 5.5 1.9 9.3 0.0 3.3 3 0 0 3 3 3 0 Myogenic determination factor 5 Cyanate_lyase PF02560.14 EPE30837.1 - 8.4e-30 102.4 0.0 1.3e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Sigma70_r4_2 PF08281.12 EPE30837.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_3 PF01381.22 EPE30837.1 - 0.051 13.6 0.1 0.085 12.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix Chitin_bind_1 PF00187.19 EPE30838.1 - 1.1e-37 128.2 297.0 6.9e-07 29.6 19.6 13.4 12 1 1 13 13 13 11 Chitin recognition protein Glyco_hydro_18 PF00704.28 EPE30839.1 - 1.2e-54 186.1 0.5 2.1e-54 185.4 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_S8 PF00082.22 EPE30839.1 - 4.2e-11 42.7 0.0 7.3e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Chitin_bind_1 PF00187.19 EPE30839.1 - 4.5e-07 30.2 9.9 4.5e-07 30.2 9.9 4.0 4 0 0 4 4 4 2 Chitin recognition protein SelK_SelG PF10961.8 EPE30840.1 - 0.012 16.2 1.5 0.47 11.1 0.0 2.7 2 0 0 2 2 2 0 Selenoprotein SelK_SelG PRIMA1 PF16101.5 EPE30840.1 - 0.032 14.3 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF2207 PF09972.9 EPE30840.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Metallophos PF00149.28 EPE30841.1 - 4.8e-13 50.1 1.5 9.8e-13 49.1 1.5 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPE30841.1 - 1.2e-10 41.9 0.0 1.8e-08 34.7 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BSP_II PF05432.11 EPE30842.1 - 0.08 12.6 12.7 0.093 12.4 12.7 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2052 PF09747.9 EPE30842.1 - 0.46 10.6 15.5 0.47 10.5 15.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) MDM10 PF12519.8 EPE30842.1 - 0.54 9.1 8.1 0.6 8.9 8.1 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DDHD PF02862.17 EPE30842.1 - 0.65 10.1 6.2 0.68 10.1 6.2 1.2 1 0 0 1 1 1 0 DDHD domain TraV PF09676.10 EPE30842.1 - 1.1 10.3 9.1 1.5 9.8 9.1 1.1 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) CPSF100_C PF13299.6 EPE30842.1 - 1.1 9.4 9.1 1.3 9.2 9.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 EPE30842.1 - 1.5 7.0 12.1 1.4 7.1 12.1 1.0 1 0 0 1 1 1 0 CDC45-like protein SpoIIP PF07454.11 EPE30842.1 - 1.8 7.9 12.4 1.8 8.0 12.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 EPE30842.1 - 2.1 7.0 13.1 2.1 7.1 13.1 1.0 1 0 0 1 1 1 0 Presenilin SPATA3 PF15662.5 EPE30842.1 - 2.3 8.8 9.1 2.2 8.9 9.1 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family FAM176 PF14851.6 EPE30842.1 - 2.3 7.9 10.4 3.3 7.4 10.4 1.4 1 0 0 1 1 1 0 FAM176 family Sec62 PF03839.16 EPE30842.1 - 2.4 7.6 6.9 2.5 7.6 6.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Pex14_N PF04695.13 EPE30842.1 - 2.8 8.6 15.1 3.1 8.4 15.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pox_Ag35 PF03286.14 EPE30842.1 - 3 7.6 13.8 4 7.2 13.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein eIF-3_zeta PF05091.12 EPE30842.1 - 3.2 6.6 10.7 3.6 6.5 10.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ALMT PF11744.8 EPE30842.1 - 3.6 6.3 6.8 3.5 6.3 6.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF908 PF06012.12 EPE30842.1 - 4.1 6.7 8.1 4 6.7 8.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SLC12 PF03522.15 EPE30842.1 - 5.3 6.0 9.2 5.1 6.0 9.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 NPR3 PF03666.13 EPE30842.1 - 6.2 5.5 10.8 6 5.5 10.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_phi PF04931.13 EPE30842.1 - 6.9 4.6 12.9 7.6 4.5 12.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi GREB1 PF15782.5 EPE30842.1 - 8.3 3.4 10.0 8.5 3.3 10.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pannexin_like PF12534.8 EPE30842.1 - 8.8 5.3 7.5 11 5.0 7.5 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF4746 PF15928.5 EPE30842.1 - 9.7 5.5 13.0 10 5.4 13.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CMAS PF02353.20 EPE30843.1 - 2e-18 66.7 0.0 4.2e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EPE30843.1 - 3.5e-15 56.2 0.0 5.1e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE30843.1 - 2.1e-13 50.8 0.0 5.2e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE30843.1 - 5.2e-13 49.5 0.0 1.1e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE30843.1 - 1.9e-12 47.2 0.0 4.3e-12 46.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE30843.1 - 2e-11 44.5 0.0 6.4e-11 42.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 EPE30843.1 - 0.00015 21.3 0.1 0.00081 19.0 0.1 1.9 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MTS PF05175.14 EPE30843.1 - 0.00028 20.5 0.1 0.0019 17.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain MetW PF07021.12 EPE30843.1 - 0.00037 20.2 0.1 0.0041 16.7 0.1 2.3 2 1 1 3 3 3 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 EPE30843.1 - 0.0053 16.1 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EPE30843.1 - 0.0066 16.2 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EPE30843.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase TPMT PF05724.11 EPE30843.1 - 0.04 13.6 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DOT1 PF08123.13 EPE30843.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 EPE30843.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Fil_haemagg_2 PF13332.6 EPE30843.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Hemagglutinin repeat MFS_1 PF07690.16 EPE30844.1 - 9.6e-27 93.8 29.4 9.6e-27 93.8 29.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily PIG-L PF02585.17 EPE30846.1 - 5.2e-26 91.8 0.0 7.2e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase GMC_oxred_C PF05199.13 EPE30847.1 - 2.9e-27 96.0 0.0 5.4e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EPE30847.1 - 1.8e-24 86.7 0.0 3.4e-21 75.9 0.0 3.0 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 EPE30847.1 - 0.00023 21.3 0.0 0.00056 20.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE30847.1 - 0.0045 16.3 0.0 0.0082 15.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE30847.1 - 0.015 14.3 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EPE30847.1 - 0.071 12.2 0.3 0.16 11.0 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 EPE30847.1 - 0.1 11.9 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EPE30847.1 - 0.19 11.0 0.0 13 4.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CDH-cyt PF16010.5 EPE30848.1 - 2.3e-45 154.5 1.1 2.3e-45 154.5 1.1 2.3 3 0 0 3 3 3 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 EPE30848.1 - 4.3e-31 108.4 0.0 7.5e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE30848.1 - 4e-21 76.1 1.1 9e-21 74.9 1.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EPE30848.1 - 2.3e-07 30.2 0.2 8.3e-07 28.4 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EPE30848.1 - 0.0008 18.2 0.8 0.0017 17.2 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EPE30848.1 - 0.00082 19.1 3.3 0.015 14.9 3.3 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EPE30848.1 - 0.00087 18.4 0.0 0.0019 17.3 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 EPE30848.1 - 0.003 17.0 0.0 0.051 12.9 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE30848.1 - 0.0035 17.5 0.1 0.0097 16.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EPE30848.1 - 0.0042 16.4 0.1 0.0072 15.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EPE30848.1 - 0.0044 16.3 0.3 0.063 12.5 0.6 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPE30848.1 - 0.0049 16.1 0.1 0.02 14.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UreD PF01774.17 EPE30850.1 - 6e-75 251.8 0.0 7.2e-75 251.6 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Fungal_trans PF04082.18 EPE30851.1 - 3.8e-17 62.2 0.2 3.8e-17 62.2 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE30851.1 - 2.9e-06 27.3 11.1 5e-06 26.5 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 EPE30851.1 - 0.065 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 SH3_9 PF14604.6 EPE30853.1 - 4.1e-29 100.2 3.7 7.7e-14 51.3 0.3 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EPE30853.1 - 1.3e-26 91.9 5.8 1.2e-12 47.2 0.5 2.5 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 EPE30853.1 - 5.5e-16 58.5 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 EPE30853.1 - 1.1e-15 57.0 0.0 2e-07 30.6 0.0 2.8 2 0 0 2 2 2 2 Variant SH3 domain Glutaredoxin PF00462.24 EPE30855.1 - 1.3e-19 70.2 0.0 2.2e-18 66.2 0.0 2.4 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EPE30855.1 - 2.1e-11 43.7 0.0 5.3e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EPE30855.1 - 0.059 13.8 0.0 0.84 10.1 0.0 2.6 2 2 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EPE30855.1 - 0.088 13.1 0.1 13 6.2 0.0 3.1 2 1 2 4 4 4 0 Thioredoxin-like TPR_12 PF13424.6 EPE30856.1 - 2.6e-14 53.3 8.9 6.7e-07 29.5 0.3 5.6 4 1 1 5 5 5 4 Tetratricopeptide repeat NB-ARC PF00931.22 EPE30856.1 - 1.2e-07 31.2 0.0 2.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.6 EPE30856.1 - 1.3e-06 28.0 6.9 0.28 11.1 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat DUF676 PF05057.14 EPE30856.1 - 3.8e-05 23.3 0.0 6.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.6 EPE30856.1 - 0.00038 20.8 0.1 0.0051 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain TPR_1 PF00515.28 EPE30856.1 - 0.00041 20.1 0.2 0.078 12.8 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ResIII PF04851.15 EPE30856.1 - 0.0069 16.4 0.0 0.022 14.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TPR_14 PF13428.6 EPE30856.1 - 0.0088 16.8 4.3 8.5 7.5 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EPE30856.1 - 0.015 15.4 4.1 0.9 9.8 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EPE30856.1 - 0.04 14.1 5.9 0.68 10.3 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Lipase_3 PF01764.25 EPE30856.1 - 0.047 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Vps51 PF08700.11 EPE30856.1 - 0.064 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Vps51/Vps67 TPR_7 PF13176.6 EPE30856.1 - 0.083 12.9 1.4 1.2e+02 3.1 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Fungal_trans PF04082.18 EPE30857.1 - 0.00035 19.7 1.5 0.00044 19.4 1.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_5 PF13857.6 EPE30858.1 - 3.5e-10 39.9 0.3 9.8e-08 32.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE30858.1 - 5.6e-10 39.7 0.0 1e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.24 EPE30858.1 - 5.7e-10 39.1 0.1 1.7e-09 37.6 0.1 1.9 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.30 EPE30858.1 - 6.6e-10 39.0 1.1 0.00052 20.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EPE30858.1 - 6.2e-08 33.0 0.2 1.5e-07 31.8 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE30858.1 - 7.4e-08 32.1 0.3 0.0043 17.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Na_H_Exchanger PF00999.21 EPE30859.1 - 2.1e-43 148.6 21.3 2.6e-43 148.3 21.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Vma12 PF11712.8 EPE30859.1 - 1.5 8.8 3.2 9.6 6.3 0.4 2.7 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Cauli_VI PF01693.16 EPE30860.1 - 1.4e-37 127.7 9.2 1.3e-18 66.9 0.4 2.8 3 0 0 3 3 3 2 Caulimovirus viroplasmin RNase_H PF00075.24 EPE30860.1 - 9.6e-28 97.2 0.0 2e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 RNase H 6PF2K PF01591.18 EPE30861.1 - 1.6e-69 233.6 0.0 9.3e-50 169.0 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EPE30861.1 - 2.5e-27 95.8 0.0 2.2e-23 82.9 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EPE30861.1 - 0.00069 19.8 0.0 0.011 15.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EPE30861.1 - 0.0017 17.8 0.0 0.031 13.7 0.0 2.1 2 0 0 2 2 2 1 Chromatin associated protein KTI12 CARD PF00619.21 EPE30861.1 - 0.12 12.4 0.2 0.32 11.0 0.2 1.7 1 0 0 1 1 1 0 Caspase recruitment domain DUF1349 PF07081.11 EPE30862.1 - 1.4e-30 106.3 0.1 2.2e-30 105.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) DUF5334 PF17268.2 EPE30864.1 - 0.0095 16.2 0.5 0.014 15.7 0.3 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5334) MLANA PF14991.6 EPE30864.1 - 1.6 9.1 0.0 1.6 9.1 0.0 2.5 2 2 2 4 4 4 0 Protein melan-A Glyoxalase PF00903.25 EPE30865.1 - 1.2e-23 83.7 0.1 3.1e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EPE30865.1 - 1.2e-11 44.8 0.0 5.9e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EPE30865.1 - 5.7e-07 29.8 0.1 0.024 14.7 0.0 3.0 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 EPE30865.1 - 0.00013 22.2 0.0 0.0044 17.2 0.0 2.6 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Aida_N PF08910.10 EPE30865.1 - 0.025 15.0 0.0 0.081 13.3 0.0 1.9 1 0 0 1 1 1 0 Aida N-terminus E1-E2_ATPase PF00122.20 EPE30867.1 - 1.9e-47 161.1 3.1 1.9e-47 161.1 3.1 2.9 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EPE30867.1 - 1.9e-17 64.3 0.2 5.9e-17 62.7 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EPE30867.1 - 2.1e-11 43.4 0.0 5.5e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EPE30867.1 - 0.0022 17.8 0.1 0.0047 16.7 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPE30867.1 - 0.0066 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) O-antigen_lig PF13425.6 EPE30867.1 - 0.12 11.1 6.1 0.32 9.8 6.1 1.6 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Mito_carr PF00153.27 EPE30869.1 - 4.9e-26 90.5 6.4 4.3e-11 42.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.21 EPE30870.1 - 6e-102 341.4 0.0 8.8e-102 340.8 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 EPE30870.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone CTD_bind PF04818.13 EPE30871.1 - 7.5e-11 42.7 0.0 1.7e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 EPE30871.1 - 1.3e-08 34.6 0.0 2.4e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MerR_1 PF13411.6 EPE30871.1 - 0.053 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 MerR HTH family regulatory protein DUF3332 PF11810.8 EPE30872.1 - 0.072 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) WD40 PF00400.32 EPE30872.1 - 0.56 11.2 15.6 20 6.3 0.3 5.4 6 0 0 6 6 6 0 WD domain, G-beta repeat ABM PF03992.16 EPE30873.1 - 1.7e-05 24.8 0.0 2.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SH2 PF00017.24 EPE30874.1 - 0.13 12.4 0.1 0.43 10.7 0.1 1.8 2 0 0 2 2 2 0 SH2 domain dCMP_cyt_deam_1 PF00383.23 EPE30875.1 - 1.8e-09 37.4 0.1 3.5e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EPE30875.1 - 1.1e-05 25.2 0.3 4.4e-05 23.2 0.1 1.9 2 0 0 2 2 2 1 MafB19-like deaminase Bd3614-deam PF14439.6 EPE30875.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase PUF PF00806.19 EPE30876.1 - 1.2e-57 188.5 16.7 1.7e-08 33.7 0.5 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF2054 PF10218.9 EPE30876.1 - 0.076 13.1 1.7 1.1 9.3 0.8 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2054) RNA_pol_Rpb2_6 PF00562.28 EPE30877.1 - 3.3e-121 405.0 0.2 4.8e-121 404.5 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EPE30877.1 - 3.9e-52 176.7 0.1 6.8e-52 175.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EPE30877.1 - 1.8e-32 112.5 0.0 6.5e-32 110.7 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EPE30877.1 - 9.5e-32 109.3 1.1 2.3e-31 108.0 1.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EPE30877.1 - 2.3e-24 85.4 0.1 4.8e-24 84.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EPE30877.1 - 1.9e-19 69.6 0.0 4.1e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EPE30877.1 - 3.7e-10 40.2 0.4 1.2e-09 38.6 0.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Choline_transpo PF04515.12 EPE30878.1 - 4.4e-29 101.7 20.1 4.4e-29 101.7 20.1 2.3 2 0 0 2 2 2 1 Plasma-membrane choline transporter Ras PF00071.22 EPE30879.1 - 4.2e-49 166.3 0.0 1.7e-38 131.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EPE30879.1 - 5.5e-29 100.8 0.0 3.1e-18 66.1 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE30879.1 - 8.2e-13 48.2 0.0 3.6e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EPE30879.1 - 1.1e-06 28.4 0.0 3.5e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EPE30879.1 - 1.2e-05 24.8 0.0 2.5e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EPE30879.1 - 6.3e-05 23.0 0.0 0.00025 21.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPE30879.1 - 0.004 17.1 0.2 1 9.3 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 EPE30879.1 - 0.023 14.3 0.2 3.3 7.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EPE30879.1 - 0.074 13.3 0.0 0.72 10.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2868 PF11067.8 EPE30879.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) WW PF00397.26 EPE30880.1 - 3.6e-08 33.3 3.2 1e-07 31.9 3.2 1.9 1 0 0 1 1 1 1 WW domain DUF2012 PF09430.10 EPE30881.1 - 1.2e-25 90.0 0.0 2.1e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) MARVEL PF01284.23 EPE30882.1 - 4e-24 85.3 15.7 5e-24 85.0 15.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain Cys_Met_Meta_PP PF01053.20 EPE30883.1 - 1.7e-150 500.8 0.0 2e-150 500.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EPE30883.1 - 3.7e-10 39.7 0.1 5.9e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EPE30883.1 - 7.4e-08 32.0 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPE30883.1 - 2.4e-07 30.1 0.2 4.4e-07 29.2 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EPE30883.1 - 4.5e-05 22.9 0.0 6.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EPE30883.1 - 0.0016 17.0 0.1 0.0021 16.6 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.16 EPE30883.1 - 0.033 13.0 0.0 0.047 12.5 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein MccV PF17508.2 EPE30883.1 - 0.24 12.0 1.8 0.46 11.1 0.1 2.3 2 0 0 2 2 2 0 Microcin V bacteriocin Sugar_tr PF00083.24 EPE30884.1 - 4.7e-77 259.8 18.3 5.3e-77 259.6 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE30884.1 - 5.4e-25 88.1 29.2 4.5e-22 78.4 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PMT PF02366.18 EPE30885.1 - 3.8e-87 291.9 15.6 3.8e-87 291.9 15.6 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EPE30885.1 - 2.1e-63 213.6 16.7 2.1e-63 213.6 16.7 2.2 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EPE30885.1 - 6.3e-37 127.2 2.9 1e-36 126.6 2.9 1.2 1 0 0 1 1 1 1 MIR domain Sugar_tr PF00083.24 EPE30886.1 - 8e-102 341.4 14.4 9.6e-102 341.1 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE30886.1 - 3.1e-30 105.3 13.4 3.1e-30 105.3 13.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_5 PF05631.14 EPE30886.1 - 0.00027 20.0 1.3 0.00048 19.2 1.3 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 EPE30886.1 - 0.0082 15.0 7.2 0.28 10.0 0.0 2.5 1 1 0 2 2 2 2 MFS_1 like family DUF2530 PF10745.9 EPE30886.1 - 0.29 11.4 2.0 2.4 8.5 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Chs7 PF12271.8 EPE30887.1 - 3e-110 368.1 7.8 3.6e-110 367.8 7.8 1.1 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF2569 PF10754.9 EPE30887.1 - 0.35 11.3 14.2 0.37 11.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) VanZ PF04892.12 EPE30887.1 - 0.66 10.7 8.8 0.24 12.1 1.1 2.3 2 0 0 2 2 2 0 VanZ like family DUF347 PF03988.12 EPE30887.1 - 0.69 10.2 0.1 0.69 10.2 0.1 4.1 3 1 1 4 4 4 0 Repeat of Unknown Function (DUF347) Ssl1 PF04056.14 EPE30888.1 - 1.5e-75 253.2 0.0 2.1e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EPE30888.1 - 5.9e-15 55.2 11.4 5.9e-15 55.2 11.4 3.1 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 EPE30888.1 - 4.2e-13 49.9 0.0 1.1e-12 48.6 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Fungal_trans PF04082.18 EPE30890.1 - 2.2e-07 30.2 6.3 6.5e-07 28.6 6.3 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE30890.1 - 3.8e-06 26.9 7.1 3.8e-06 26.9 7.1 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 EPE30891.1 - 1e-21 77.6 0.4 3.1e-21 76.0 0.4 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE30891.1 - 3e-09 36.5 0.3 8.3e-09 35.1 0.2 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE30891.1 - 1.5e-06 28.1 3.6 4.8e-05 23.1 1.2 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE30891.1 - 2.5e-06 27.6 0.2 6.3e-06 26.3 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE30891.1 - 0.00014 21.1 0.2 0.00027 20.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EPE30891.1 - 0.00064 18.7 0.3 0.041 12.7 0.1 2.6 2 1 0 3 3 3 1 Tryptophan halogenase Amino_oxidase PF01593.24 EPE30891.1 - 0.0011 18.4 1.2 0.25 10.6 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 EPE30891.1 - 0.004 16.4 1.2 0.011 15.0 1.2 1.9 1 1 0 1 1 1 1 Thi4 family SE PF08491.10 EPE30891.1 - 0.0042 16.2 0.0 2.3 7.2 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase HI0933_like PF03486.14 EPE30891.1 - 0.02 13.6 0.4 0.046 12.4 0.4 1.7 1 1 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 EPE30891.1 - 0.038 14.5 0.2 0.096 13.3 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE30891.1 - 0.07 12.2 0.2 1.6 7.7 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EPE30891.1 - 0.14 12.1 0.9 8.4 6.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 EPE30891.1 - 0.17 11.0 1.9 3.7 6.5 0.3 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pkinase PF00069.25 EPE30892.1 - 3.4e-10 39.7 0.0 6.6e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE30892.1 - 0.00031 20.1 0.0 0.079 12.2 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase RTA1 PF04479.13 EPE30893.1 - 1.9e-70 236.7 8.8 1.9e-70 236.7 8.8 1.7 1 1 1 2 2 2 1 RTA1 like protein MIG-14_Wnt-bd PF06664.12 EPE30893.1 - 0.0045 16.2 11.4 0.33 10.1 6.2 2.2 1 1 1 2 2 2 2 Wnt-binding factor required for Wnt secretion PDR_CDR PF06422.12 EPE30893.1 - 0.024 14.5 0.8 0.27 11.1 0.1 2.9 3 0 0 3 3 3 0 CDR ABC transporter DUF3339 PF11820.8 EPE30893.1 - 0.29 11.4 4.4 0.35 11.1 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3339) DUF2615 PF11027.8 EPE30893.1 - 0.4 10.9 1.2 8.1 6.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) DUF3671 PF12420.8 EPE30893.1 - 5.4 7.1 7.4 7.5 6.7 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function Zn_clus PF00172.18 EPE30894.1 - 1.3e-10 41.2 9.2 2.7e-10 40.2 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE30894.1 - 2.2e-05 23.5 0.1 3.5e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Velvet PF11754.8 EPE30895.1 - 2.1e-51 175.3 0.0 5.9e-33 114.8 0.0 4.4 2 2 1 3 3 3 2 Velvet factor Jiraiya PF15038.6 EPE30896.1 - 0.24 10.8 5.1 0.073 12.5 1.2 2.1 2 0 0 2 2 2 0 Jiraiya DUF1043 PF06295.12 EPE30897.1 - 0.013 15.5 2.7 0.033 14.2 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Pkinase PF00069.25 EPE30898.1 - 3.1e-15 56.3 0.0 0.00054 19.4 0.0 3.3 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EPE30898.1 - 4.1e-09 36.1 0.0 0.1 11.8 0.0 4.0 2 2 0 2 2 2 2 Protein tyrosine kinase Rsd_AlgQ PF04353.13 EPE30898.1 - 0.00021 21.3 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Pkinase PF00069.25 EPE30899.1 - 8.2e-12 45.0 0.0 1e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE30899.1 - 2.2e-07 30.4 0.0 0.00055 19.3 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Rsd_AlgQ PF04353.13 EPE30899.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Vps54 PF07928.12 EPE30900.1 - 3e-43 147.5 0.4 9.3e-43 145.9 0.4 1.9 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 EPE30900.1 - 0.00082 18.7 5.1 0.0024 17.2 5.1 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex FlbT PF07378.11 EPE30900.1 - 0.21 11.7 2.2 38 4.4 0.5 3.8 4 0 0 4 4 4 0 Flagellar protein FlbT Pkinase PF00069.25 EPE30901.1 - 0.00021 20.7 0.0 0.00058 19.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain AMP-binding PF00501.28 EPE30902.1 - 4.6e-75 252.8 0.0 5.8e-75 252.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme FAD_binding_3 PF01494.19 EPE30903.1 - 2.7e-23 82.8 0.0 1e-22 80.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPE30903.1 - 7.1e-07 29.1 0.0 0.0099 15.5 0.0 2.8 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE30903.1 - 0.0016 17.7 0.0 0.0046 16.2 0.0 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EPE30903.1 - 0.014 14.5 0.0 0.54 9.3 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.6 EPE30903.1 - 0.028 14.7 0.0 0.082 13.1 0.0 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPE30903.1 - 0.045 12.8 0.0 0.34 9.9 0.0 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein CaM_binding PF07839.11 EPE30903.1 - 0.078 13.7 0.1 0.15 12.8 0.1 1.4 1 0 0 1 1 1 0 Plant calmodulin-binding domain FAD_binding_2 PF00890.24 EPE30903.1 - 0.11 11.6 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Ins_allergen_rp PF06757.13 EPE30905.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification Vps39_2 PF10367.9 EPE30905.1 - 1.3 9.6 6.0 8.3 6.9 2.8 2.7 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 Viral_DNA_bp PF00747.17 EPE30905.1 - 1.7 5.7 2.8 2.3 5.3 2.8 1.1 1 0 0 1 1 1 0 ssDNA binding protein FYVE PF01363.21 EPE30905.1 - 5.3 7.2 15.2 1.2 9.3 11.0 2.1 2 0 0 2 2 2 0 FYVE zinc finger FYVE_2 PF02318.16 EPE30905.1 - 8.6 6.6 16.4 0.13 12.5 6.0 2.6 1 1 1 2 2 2 0 FYVE-type zinc finger Laminin_I PF06008.14 EPE30906.1 - 0.038 13.7 0.8 0.053 13.2 0.8 1.2 1 0 0 1 1 1 0 Laminin Domain I DUF745 PF05335.13 EPE30906.1 - 0.041 13.6 4.0 0.064 13.0 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) p450 PF00067.22 EPE30908.1 - 5.8e-53 180.3 0.0 8e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Seadorna_VP7 PF07387.11 EPE30909.1 - 0.00072 18.7 0.0 0.0014 17.8 0.0 1.4 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.23 EPE30909.1 - 0.012 15.5 0.0 0.069 13.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EPE30909.1 - 0.063 12.9 0.0 0.21 11.1 0.0 1.8 1 1 0 1 1 1 0 RIO1 family Pkinase PF00069.25 EPE30909.1 - 0.086 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Choline_kinase PF01633.20 EPE30909.1 - 0.14 11.7 0.1 0.55 9.8 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 EPE30909.1 - 0.18 11.2 0.0 3.3 7.0 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.6 EPE30910.1 - 2.1 8.6 4.8 66 3.9 0.4 4.1 3 0 0 3 3 3 0 Leucine Rich repeat NDT80_PhoG PF05224.12 EPE30911.1 - 5.2e-41 140.9 0.0 7e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family PetN PF03742.14 EPE30911.1 - 0.011 15.6 0.2 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 PetN FMO-like PF00743.19 EPE30912.1 - 6.7e-10 38.0 0.1 1.9e-09 36.5 0.1 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EPE30912.1 - 6.3e-09 35.5 0.0 2.9e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE30912.1 - 1.1e-07 31.4 0.0 1e-06 28.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE30912.1 - 1.1e-06 28.8 0.0 3.5e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EPE30912.1 - 0.0031 18.1 1.8 1.4 9.5 0.2 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE30912.1 - 0.0081 15.8 0.1 0.09 12.3 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EPE30912.1 - 0.015 14.5 0.0 7 5.7 0.0 2.8 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EPE30912.1 - 0.036 13.3 0.0 0.86 8.8 0.0 2.2 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 EPE30912.1 - 0.078 13.0 0.3 0.86 9.6 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EPE30913.1 - 7.5e-07 28.4 0.0 1.3e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Tryptophan halogenase DAO PF01266.24 EPE30913.1 - 1.9e-05 24.5 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE30913.1 - 0.0004 20.6 0.0 0.00068 19.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE30913.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE30913.1 - 0.02 15.4 0.1 0.13 12.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPE30913.1 - 0.022 14.7 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EPE30913.1 - 0.024 13.4 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein zf-ribbon_3 PF13248.6 EPE30914.1 - 0.00027 20.2 1.0 0.00067 19.0 1.0 1.7 1 0 0 1 1 1 1 zinc-ribbon domain HypA PF01155.19 EPE30914.1 - 0.054 13.5 0.2 0.1 12.6 0.2 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 EPE30914.1 - 0.11 12.8 0.2 0.32 11.4 0.1 1.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF35_N PF12172.8 EPE30914.1 - 0.67 9.9 3.7 1.5 8.7 0.2 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) UPF0547 PF10571.9 EPE30914.1 - 1.3 9.1 6.8 0.22 11.7 0.6 2.6 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Beta_helix PF13229.6 EPE30915.1 - 2.1e-10 40.7 13.5 8.9e-09 35.4 11.2 2.4 1 1 1 2 2 2 2 Right handed beta helix region Chondroitinas_B PF14592.6 EPE30915.1 - 6.2e-06 25.4 0.1 1.4e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Chondroitinase B NosD PF05048.13 EPE30915.1 - 3.6e-05 23.2 12.5 0.0059 15.9 7.1 2.4 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 EPE30915.1 - 0.00054 19.4 0.2 0.00054 19.4 0.2 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1565) Dehydratase_LU PF02286.15 EPE30915.1 - 0.16 10.5 0.1 0.25 9.9 0.1 1.2 1 0 0 1 1 1 0 Dehydratase large subunit F-box-like PF12937.7 EPE30916.1 - 5.1e-07 29.5 0.0 1.4e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE30916.1 - 1.5e-05 24.8 0.0 3.6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain DUF4055 PF13264.6 EPE30916.1 - 0.27 11.4 3.0 0.59 10.3 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4055) Amidohydro_1 PF01979.20 EPE30917.1 - 3.3e-21 76.0 0.0 3.3e-20 72.7 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPE30917.1 - 6.6e-10 39.0 0.4 3.4e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family GST_C_5 PF16865.5 EPE30917.1 - 0.064 13.8 0.0 1.4 9.6 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF1981 PF09324.10 EPE30917.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) adh_short PF00106.25 EPE30918.1 - 6e-08 32.4 0.0 3.8e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE30918.1 - 0.00018 21.2 0.0 0.00032 20.3 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE30918.1 - 0.0012 18.8 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Transglut_core PF01841.19 EPE30919.1 - 7.1e-12 45.8 0.0 2.2e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 Transglutaminase-like superfamily Thioredoxin PF00085.20 EPE30919.1 - 1.8e-11 44.0 0.0 2.9e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EPE30919.1 - 2e-05 24.1 0.0 3.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family N-glycanase_C PF09113.10 EPE30919.1 - 0.017 14.9 0.5 0.033 14.0 0.0 1.7 2 0 0 2 2 2 0 Peptide-N-glycosidase F, C terminal Thioredoxin_6 PF13848.6 EPE30919.1 - 0.017 15.0 0.0 0.041 13.8 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EPE30919.1 - 0.096 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain DUF553 PF04473.12 EPE30919.1 - 0.12 11.8 0.0 2.2 7.8 0.0 2.3 1 1 0 1 1 1 0 Transglutaminase-like domain AT_hook PF02178.19 EPE30922.1 - 7.1 6.9 9.9 0.45 10.5 3.1 2.7 2 0 0 2 2 2 0 AT hook motif PDZ_1 PF12812.7 EPE30924.1 - 1.3e-56 188.5 0.0 4.2e-36 122.8 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 EPE30924.1 - 6.5e-27 95.3 2.4 1.9e-21 77.5 0.0 2.4 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 EPE30924.1 - 1.3e-14 53.8 0.3 8.9e-06 25.5 0.2 4.0 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 EPE30924.1 - 2.8e-13 50.0 0.8 2.6e-05 24.5 0.0 4.6 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 EPE30924.1 - 4.6e-10 39.7 0.0 0.00014 22.2 0.0 3.8 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 EPE30924.1 - 0.0004 20.3 0.0 0.0011 18.8 0.0 1.7 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 EPE30924.1 - 0.001 19.0 0.2 1 9.4 0.1 3.9 4 0 0 4 4 4 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 EPE30924.1 - 0.041 13.6 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal DUF31 PF01732.16 EPE30924.1 - 0.24 10.9 0.2 0.38 10.2 0.2 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.9 EPE30924.1 - 0.26 9.9 0.1 0.49 9.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase S46 EthD PF07110.11 EPE30925.1 - 0.00041 21.4 0.0 0.00066 20.8 0.0 1.5 1 1 0 1 1 1 1 EthD domain DUF1459 PF07312.11 EPE30928.1 - 3.3 8.0 4.8 11 6.3 4.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) Fungal_trans PF04082.18 EPE30929.1 - 1.1e-24 86.9 0.0 1.8e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE30929.1 - 7.6e-09 35.5 11.3 1.3e-08 34.8 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPE30930.1 - 7e-37 127.2 13.4 7e-37 127.2 13.4 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE30930.1 - 1.1e-08 34.5 0.7 1.1e-08 34.5 0.7 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter DUF465 PF04325.13 EPE30930.1 - 0.039 14.0 0.6 0.06 13.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Antifungal_prot PF11402.8 EPE30930.1 - 0.067 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Antifungal protein Ccdc124 PF06244.12 EPE30931.1 - 1.6e-24 86.9 24.3 1.6e-24 86.9 24.3 2.5 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 Bud13 PF09736.9 EPE30931.1 - 2.4 8.5 28.5 1.5 9.2 7.9 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex UQ_con PF00179.26 EPE30932.1 - 8.4e-08 32.0 1.0 1.4e-07 31.2 1.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EPE30932.1 - 0.042 14.1 0.5 0.24 11.7 0.2 2.1 2 0 0 2 2 2 0 RWD domain GFA PF04828.14 EPE30934.1 - 3.1e-05 24.2 8.6 0.011 16.1 0.1 3.1 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 EPE30934.1 - 7.9 6.7 12.5 1.7 8.9 1.1 3.5 3 2 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like Peptidase_S58 PF03576.14 EPE30935.1 - 8.2e-87 291.5 0.8 9.6e-87 291.3 0.8 1.0 1 0 0 1 1 1 1 Peptidase family S58 DUF3445 PF11927.8 EPE30936.1 - 3.1e-46 157.8 0.0 3.7e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) MIT PF04212.18 EPE30937.1 - 0.0061 16.6 0.1 0.017 15.2 0.0 1.7 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain DEAD PF00270.29 EPE30938.1 - 4.5e-45 153.6 0.1 8.9e-45 152.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE30938.1 - 2.2e-22 79.5 0.3 3.5e-21 75.6 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE30938.1 - 6.4e-06 26.3 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EPE30938.1 - 0.00055 19.2 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase LUD_dom PF02589.15 EPE30938.1 - 0.076 12.7 0.0 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 LUD domain Glyco_hydro_10 PF00331.20 EPE30939.1 - 7e-89 298.1 0.9 8e-89 297.9 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 WD40 PF00400.32 EPE30940.1 - 1.6e-14 54.1 11.8 0.042 14.7 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE30940.1 - 0.00033 20.9 0.2 0.09 13.1 0.2 3.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain FG-GAP PF01839.23 EPE30940.1 - 0.17 12.1 1.7 0.47 10.6 1.7 1.8 1 0 0 1 1 1 0 FG-GAP repeat 2OG-FeII_Oxy_2 PF13532.6 EPE30941.1 - 6.8e-37 127.6 0.0 9.3e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 EPE30941.1 - 2.2e-08 34.1 4.0 4e-08 33.2 4.0 1.4 1 0 0 1 1 1 1 GRF zinc finger DUF3328 PF11807.8 EPE30942.1 - 6.1e-37 127.5 1.3 7e-37 127.3 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EPE30943.1 - 5.9e-39 134.1 0.7 7.4e-39 133.8 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Ribosomal_S19 PF00203.21 EPE30944.1 - 0.16 11.8 1.6 32 4.5 0.5 3.7 1 1 1 2 2 2 0 Ribosomal protein S19 UCR_TM PF02921.14 EPE30945.1 - 0.15 12.6 0.6 0.39 11.2 0.6 1.7 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region ketoacyl-synt PF00109.26 EPE30946.1 - 2.1e-74 250.3 0.0 5.4e-74 249.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 EPE30946.1 - 3.9e-72 243.4 0.1 6.4e-72 242.7 0.1 1.3 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 EPE30946.1 - 7.6e-66 222.4 0.0 1.1e-65 221.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PS-DH PF14765.6 EPE30946.1 - 2.6e-55 187.8 0.0 4.7e-55 186.9 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EPE30946.1 - 1.7e-50 171.5 0.0 1.1e-48 165.6 0.0 2.6 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EPE30946.1 - 1.9e-44 152.4 0.0 3.6e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EPE30946.1 - 3.8e-36 124.6 0.0 4.1e-35 121.2 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EPE30946.1 - 3.7e-32 110.8 0.0 9.4e-32 109.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EPE30946.1 - 9.8e-19 67.9 0.0 4.7e-18 65.8 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EPE30946.1 - 1.7e-15 57.1 0.1 2.7e-08 34.0 0.0 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 EPE30946.1 - 2.3e-14 53.5 0.0 6.4e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 EPE30946.1 - 4e-14 52.7 0.0 6.4e-10 38.9 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 EPE30946.1 - 9.6e-14 51.9 0.0 1.5e-12 48.0 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE30946.1 - 1.1e-13 51.7 0.0 4.7e-13 49.6 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE30946.1 - 3.4e-13 49.7 0.0 1.1e-12 48.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EPE30946.1 - 4.7e-11 43.1 0.0 1.2e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension 3Beta_HSD PF01073.19 EPE30946.1 - 5.4e-11 42.0 0.0 4e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EPE30946.1 - 3.5e-09 36.4 0.1 2.2e-08 33.8 0.0 2.4 3 0 0 3 3 3 1 short chain dehydrogenase Ubie_methyltran PF01209.18 EPE30946.1 - 5.8e-06 25.8 0.0 1.8e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 EPE30946.1 - 2.5e-05 23.8 0.1 5.2e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain AMP-binding_C PF13193.6 EPE30946.1 - 2.8e-05 25.0 0.1 0.00011 23.1 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_24 PF13578.6 EPE30946.1 - 0.0002 22.3 0.0 0.048 14.7 0.0 3.6 3 0 0 3 3 2 1 Methyltransferase domain DUF938 PF06080.12 EPE30946.1 - 0.0032 17.3 0.0 0.0086 15.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF938) RrnaAD PF00398.20 EPE30946.1 - 0.0074 15.4 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Shikimate_DH PF01488.20 EPE30946.1 - 0.067 13.3 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 EPE30946.1 - 0.12 11.7 0.0 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase PCMT PF01135.19 EPE30946.1 - 0.17 11.6 0.1 0.81 9.4 0.0 2.0 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EPE30946.1 - 0.18 11.4 0.0 0.74 9.4 0.0 2.0 2 0 0 2 2 1 0 Methionine biosynthesis protein MetW DUF1100 PF06500.11 EPE30947.1 - 3e-06 26.3 0.0 4.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 EPE30947.1 - 5.4e-06 27.2 0.3 8.4e-06 26.5 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EPE30947.1 - 0.00028 20.4 0.0 0.00061 19.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EPE30947.1 - 0.0031 17.2 0.0 0.07 12.8 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE30947.1 - 0.0092 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DEC1 PF15859.5 EPE30948.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Deleted in esophageal cancer 1 family DUF1772 PF08592.11 EPE30950.1 - 1.2e-07 32.1 3.3 1.2e-07 32.1 3.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Amidohydro_1 PF01979.20 EPE30951.1 - 4.5e-25 88.7 2.5 9.3e-14 51.5 0.1 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EPE30951.1 - 7.8e-12 45.4 0.7 1e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family IMPa_N_2 PF18650.1 EPE30951.1 - 0.06 12.6 0.0 0.13 11.5 0.0 1.5 1 1 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain W2 PF02020.18 EPE30951.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Zn_clus PF00172.18 EPE30952.1 - 0.00015 21.8 9.5 0.00026 21.0 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPE30953.1 - 1.4e-40 139.3 55.6 1.4e-40 139.3 55.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily 7TM_GPCR_Srh PF10318.9 EPE30953.1 - 2.3 7.2 19.1 0.059 12.4 11.6 1.9 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh ADH_zinc_N PF00107.26 EPE30954.1 - 1.2e-08 35.0 0.0 2.7e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE30954.1 - 2.3e-05 24.2 0.2 5.9e-05 22.9 0.2 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EPE30954.1 - 0.0033 18.5 0.0 0.0058 17.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_4 PF01565.23 EPE30956.1 - 1.9e-24 86.0 0.5 3e-23 82.1 1.4 2.1 2 0 0 2 2 2 1 FAD binding domain ABC2_membrane PF01061.24 EPE30957.1 - 4.6e-88 294.1 56.8 8.2e-46 156.1 19.4 3.8 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EPE30957.1 - 9.6e-40 136.3 0.1 5.9e-19 68.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EPE30957.1 - 3.8e-38 129.3 10.1 1.3e-34 118.0 0.1 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EPE30957.1 - 4.4e-14 52.9 0.0 1.4e-13 51.2 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EPE30957.1 - 1.3e-07 32.2 0.1 0.0023 18.4 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EPE30957.1 - 3.9e-06 26.9 0.1 0.0043 17.0 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_25 PF13481.6 EPE30957.1 - 6.1e-06 26.0 0.1 5.5e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EPE30957.1 - 8.8e-05 22.7 0.2 0.027 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EPE30957.1 - 0.00016 21.0 13.1 0.00016 21.0 13.1 4.3 3 2 1 5 5 5 2 ABC-2 family transporter protein AAA_18 PF13238.6 EPE30957.1 - 0.00024 21.7 0.1 0.047 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EPE30957.1 - 0.00039 20.1 1.8 0.054 13.3 0.1 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EPE30957.1 - 0.00048 20.4 0.8 1.4 9.2 0.2 3.2 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EPE30957.1 - 0.00049 20.0 0.0 1.4 8.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 EPE30957.1 - 0.0021 17.7 0.3 0.15 11.6 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EPE30957.1 - 0.003 17.5 1.3 1.1 9.2 0.1 2.9 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.6 EPE30957.1 - 0.0059 17.0 0.3 0.75 10.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.19 EPE30957.1 - 0.0062 16.0 0.1 0.4 10.1 0.0 3.1 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EPE30957.1 - 0.01 15.9 0.0 3.7 7.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 EPE30957.1 - 0.015 15.1 0.2 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EPE30957.1 - 0.019 15.4 0.1 12 6.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 EPE30957.1 - 0.19 11.6 0.3 2.2 8.1 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF3611 PF12263.8 EPE30957.1 - 2.3 8.1 9.5 3.5 7.5 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) XPA_C PF05181.12 EPE30959.1 - 2.1e-25 88.4 1.8 4.6e-25 87.3 1.8 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 EPE30959.1 - 1.9e-05 24.6 3.3 7e-05 22.8 0.2 2.3 2 0 0 2 2 2 1 XPA protein N-terminal Vma12 PF11712.8 EPE30959.1 - 0.34 11.0 2.4 3.7 7.6 0.2 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Pho88 PF10032.9 EPE30960.1 - 6.2e-78 260.2 1.0 6.9e-78 260.1 1.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Striatin PF08232.12 EPE30961.1 - 1.4e-42 145.9 1.4 3.4e-42 144.7 1.4 1.7 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 EPE30961.1 - 1.6e-25 88.9 21.9 0.00018 22.2 0.3 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE30961.1 - 2.3e-05 24.6 0.1 0.94 9.8 0.0 4.8 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE30961.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EPE30961.1 - 0.083 11.8 0.0 0.53 9.2 0.0 2.3 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CALCOCO1 PF07888.11 EPE30961.1 - 0.11 11.4 6.4 0.17 10.7 6.4 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADH_N_2 PF16884.5 EPE30961.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase HET PF06985.11 EPE30962.1 - 1.3e-24 87.3 0.0 2.4e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PIG-P PF08510.12 EPE30963.1 - 6.7e-53 177.7 2.1 8.5e-53 177.4 2.1 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 EPE30963.1 - 0.19 12.0 9.1 0.37 11.1 9.1 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Tape_meas_lam_C PF09718.10 EPE30964.1 - 0.12 12.5 0.2 5.5 7.2 0.0 2.8 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Abhydrolase_6 PF12697.7 EPE30965.1 - 2.3e-13 51.3 5.7 4.6e-13 50.3 5.7 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE30965.1 - 2e-10 40.4 0.1 3.2e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE30965.1 - 2e-08 34.2 1.0 3.3e-08 33.5 1.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPE30965.1 - 0.027 13.9 1.8 0.05 13.1 1.8 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DLH PF01738.18 EPE30965.1 - 0.2 11.2 0.2 3.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF3494 PF11999.8 EPE30966.1 - 7.9e-37 126.9 19.3 9.7e-37 126.6 19.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3494) Pro-kuma_activ PF09286.11 EPE30967.1 - 6.3e-40 136.8 0.3 1.1e-39 136.0 0.3 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EPE30967.1 - 6.3e-05 22.4 0.3 0.00012 21.5 0.3 1.3 1 0 0 1 1 1 1 Subtilase family Myb_DNA-binding PF00249.31 EPE30968.1 - 6.2e-09 35.9 0.2 0.0006 19.9 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPE30968.1 - 2.6e-05 24.4 2.2 0.014 15.6 0.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DS PF01916.17 EPE30969.1 - 7e-127 422.6 0.0 8e-127 422.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Carbam_trans_N PF02543.15 EPE30969.1 - 0.081 12.6 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus HSF_DNA-bind PF00447.17 EPE30970.1 - 6.1e-28 97.3 0.2 1.7e-27 95.9 0.2 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding DUF5082 PF16888.5 EPE30970.1 - 0.014 15.7 1.8 0.83 9.9 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Phage_HK97_TLTM PF06120.11 EPE30970.1 - 0.048 12.8 0.3 0.1 11.8 0.3 1.5 1 0 0 1 1 1 0 Tail length tape measure protein G-gamma PF00631.22 EPE30971.1 - 0.23 11.5 2.2 0.92 9.6 2.6 1.9 2 0 0 2 2 2 0 GGL domain DivIC PF04977.15 EPE30971.1 - 1.1 9.1 4.6 0.94 9.3 2.8 1.8 2 0 0 2 2 2 0 Septum formation initiator LapA_dom PF06305.11 EPE30971.1 - 2.2 8.1 5.1 0.89 9.4 2.4 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Pro_isomerase PF00160.21 EPE30972.1 - 1.2e-37 129.6 0.0 2.4e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3746 PF12562.8 EPE30974.1 - 0.059 13.3 2.1 0.16 11.9 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3746) AAA PF00004.29 EPE30976.1 - 1.8e-16 60.7 0.0 3.3e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EPE30976.1 - 2.9e-14 53.2 0.0 1.1e-13 51.4 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EPE30976.1 - 6.3e-13 48.8 0.0 2.6e-12 46.8 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EPE30976.1 - 4.9e-09 36.4 0.0 1e-08 35.3 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 EPE30976.1 - 1.9e-07 31.0 0.3 5.6e-07 29.5 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 EPE30976.1 - 2.9e-07 30.7 0.1 8.8e-07 29.2 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_24 PF13479.6 EPE30976.1 - 3.4e-06 26.9 0.0 6.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPE30976.1 - 3.4e-06 27.6 0.0 3.1e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain DNA_pol3_delta PF06144.13 EPE30976.1 - 9.3e-06 25.5 0.8 1.5e-05 24.8 0.2 1.6 2 0 0 2 2 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.14 EPE30976.1 - 9.5e-06 25.7 0.1 3.3e-05 23.9 0.1 1.9 1 1 1 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPE30976.1 - 1.5e-05 25.3 0.0 4.3e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EPE30976.1 - 3.4e-05 23.8 0.2 0.00016 21.6 0.1 1.8 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EPE30976.1 - 0.00017 21.3 0.0 0.00067 19.4 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EPE30976.1 - 0.00027 20.2 0.0 0.00049 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 EPE30976.1 - 0.0003 21.2 0.3 0.00082 19.7 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EPE30976.1 - 0.00082 19.2 0.2 0.0029 17.4 0.1 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EPE30976.1 - 0.001 19.1 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EPE30976.1 - 0.002 17.6 0.4 0.35 10.3 0.0 2.3 1 1 1 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 EPE30976.1 - 0.004 17.4 0.0 0.0078 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EPE30976.1 - 0.0043 16.6 0.0 0.059 12.9 0.0 2.3 1 1 0 2 2 2 1 P-loop containing dynein motor region ResIII PF04851.15 EPE30976.1 - 0.0067 16.4 0.0 0.085 12.8 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EPE30976.1 - 0.0088 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 EPE30976.1 - 0.011 16.3 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain VTC PF09359.10 EPE30976.1 - 0.013 14.9 0.2 0.019 14.4 0.2 1.2 1 0 0 1 1 1 0 VTC domain AAA_25 PF13481.6 EPE30976.1 - 0.023 14.3 0.1 0.57 9.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain DEAD PF00270.29 EPE30976.1 - 0.025 14.4 0.3 0.092 12.5 0.3 1.8 1 1 1 2 2 2 0 DEAD/DEAH box helicase TniB PF05621.11 EPE30976.1 - 0.036 13.5 0.1 0.26 10.7 0.1 2.2 1 1 0 1 1 1 0 Bacterial TniB protein Viral_helicase1 PF01443.18 EPE30976.1 - 0.038 13.7 0.1 0.12 12.1 0.0 1.9 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 EPE30976.1 - 0.051 13.0 0.1 0.32 10.3 0.1 2.4 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EPE30976.1 - 0.093 13.1 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.12 EPE30976.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Flavi_DEAD PF07652.14 EPE30976.1 - 0.19 11.7 2.2 1.9 8.4 0.2 2.8 2 1 1 3 3 3 0 Flavivirus DEAD domain Glyco_hydro_61 PF03443.14 EPE30977.1 - 1.1e-63 214.9 0.8 1.5e-63 214.4 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Methyltransf_23 PF13489.6 EPE30978.1 - 1.9e-07 31.1 0.0 3.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE30978.1 - 0.00099 18.9 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE30978.1 - 0.16 12.6 0.0 0.35 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain P21-Arc PF04062.14 EPE30979.1 - 1.8e-70 236.5 0.0 2.2e-68 229.7 0.0 2.0 1 1 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.13 EPE30980.1 - 7e-121 402.9 0.0 9.2e-121 402.6 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family MINDY_DUB PF04424.13 EPE30981.1 - 7.8e-27 93.6 0.0 1.3e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase Glyco_hydro_16 PF00722.21 EPE30982.1 - 4.8e-08 32.7 0.0 2.1e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 IBR PF01485.21 EPE30984.1 - 0.017 15.4 1.8 0.017 15.4 1.8 3.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Copper-bind PF00127.20 EPE30987.1 - 0.0001 22.7 0.2 0.00024 21.5 0.2 1.6 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 EPE30987.1 - 0.00048 20.1 0.1 0.00092 19.2 0.1 1.5 1 0 0 1 1 1 1 Plastocyanin-like domain THEG4 PF15834.5 EPE30987.1 - 1.1 9.2 3.8 0.97 9.4 0.3 2.0 2 0 0 2 2 2 0 Testis highly expressed protein 4 NinE PF05322.11 EPE30988.1 - 0.078 12.9 2.8 1.3 8.9 0.4 2.7 2 0 0 2 2 2 0 NINE Protein Cytochrom_D1 PF02239.16 EPE30989.1 - 7.4e-06 24.7 2.3 7.8e-05 21.4 0.5 2.7 1 1 0 2 2 2 1 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 EPE30989.1 - 6.5e-05 23.2 0.1 8.1 6.8 0.1 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 EPE30989.1 - 7.2e-05 22.5 0.9 0.00061 19.5 0.1 2.7 2 2 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 EPE30989.1 - 8.1e-05 22.0 0.5 0.011 15.1 0.1 2.7 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 EPE30989.1 - 0.035 14.1 0.1 30 4.7 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF4221 PF13970.6 EPE30989.1 - 0.12 11.9 0.0 10 5.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4221) FlaG PF03646.15 EPE30989.1 - 0.28 11.3 5.3 1.7 8.9 0.1 3.1 3 0 0 3 3 3 0 FlaG protein PD40 PF07676.12 EPE30990.1 - 6.6e-51 169.3 19.3 1.6e-10 40.6 0.4 10.6 9 1 1 10 10 10 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 EPE30990.1 - 7e-08 31.6 7.8 0.062 12.0 0.0 6.1 5 1 1 6 6 6 4 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF5050 PF16472.5 EPE30990.1 - 1.7e-06 27.5 0.0 0.031 13.5 0.0 3.5 3 1 0 4 4 4 2 Domain of unknown function (DUF5050) WD40 PF00400.32 EPE30990.1 - 0.01 16.6 9.7 12 6.9 0.3 5.5 5 1 0 5 5 5 0 WD domain, G-beta repeat SGL PF08450.12 EPE30990.1 - 0.021 14.4 3.4 0.49 9.9 0.2 3.8 2 2 1 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Bac_rhamnosid_N PF08531.10 EPE30990.1 - 0.052 13.4 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain DUF3748 PF12566.8 EPE30990.1 - 0.094 12.7 3.3 16 5.5 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3748) MMR_HSR1 PF01926.23 EPE30994.1 - 4.1e-08 33.3 0.6 1.8e-06 28.0 0.6 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EPE30994.1 - 1.8e-05 24.9 0.1 0.088 12.9 0.0 3.4 3 0 0 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EPE30994.1 - 0.00019 21.4 0.0 0.00053 19.9 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 EPE30994.1 - 0.00035 20.0 0.0 0.59 9.4 0.0 2.5 2 0 0 2 2 2 2 AIG1 family AAA_16 PF13191.6 EPE30994.1 - 0.00054 20.4 0.0 0.0039 17.6 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain Septin PF00735.18 EPE30994.1 - 0.0023 17.3 0.1 0.0076 15.6 0.1 1.8 1 1 0 1 1 1 1 Septin AAA_23 PF13476.6 EPE30994.1 - 0.0023 18.5 0.1 0.0023 18.5 0.1 2.2 2 1 0 2 2 1 1 AAA domain AAA_29 PF13555.6 EPE30994.1 - 0.0026 17.5 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EPE30994.1 - 0.0059 16.9 0.0 0.26 11.6 0.0 3.3 3 1 0 3 3 3 1 AAA domain IIGP PF05049.13 EPE30994.1 - 0.0088 15.1 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 EPE30994.1 - 0.01 15.2 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_7 PF12775.7 EPE30994.1 - 0.012 15.2 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 EPE30994.1 - 0.012 14.7 0.3 0.034 13.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 EPE30994.1 - 0.014 16.0 0.7 0.12 12.9 0.0 2.9 3 1 1 4 4 3 0 ABC transporter Sigma54_activat PF00158.26 EPE30994.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain GTP_EFTU PF00009.27 EPE30994.1 - 0.075 12.6 0.1 0.25 10.9 0.1 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Roc PF08477.13 EPE30994.1 - 0.11 12.7 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EPE30994.1 - 0.12 12.1 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain TBCC_N PF16752.5 EPE30994.1 - 0.15 12.5 6.4 4.1 7.9 0.2 3.7 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Filament PF00038.21 EPE30996.1 - 0.022 14.4 52.8 0.04 13.5 8.7 3.5 2 2 1 3 3 3 0 Intermediate filament protein PKcGMP_CC PF16808.5 EPE30996.1 - 2.3 8.1 14.0 15 5.6 0.1 4.7 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HET PF06985.11 EPE30997.1 - 7.3e-26 91.3 0.0 2.5e-25 89.6 0.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 EPE30997.1 - 5.1e-19 68.7 0.0 8.5e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE30997.1 - 3.9e-13 49.3 0.0 6.8e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EPE30998.1 - 1.3e-19 70.6 0.0 2.8e-18 66.3 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE30998.1 - 5.7e-11 42.2 0.0 4.8e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase HTH_25 PF13413.6 EPE31000.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Avl9 PF09794.9 EPE31001.1 - 1.6e-143 478.0 0.0 2.2e-143 477.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 EPE31001.1 - 1.7e-06 27.9 1.6 4.2e-05 23.3 0.1 3.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 EPE31001.1 - 2.4e-06 27.5 0.0 0.00021 21.2 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis GST_N PF02798.20 EPE31002.1 - 3.1e-14 53.1 0.0 5.3e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPE31002.1 - 1e-11 45.1 0.0 1.9e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPE31002.1 - 6.1e-10 39.3 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EPE31002.1 - 1.8e-09 37.7 0.0 2.9e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPE31002.1 - 3.1e-08 33.7 0.1 5.5e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPE31002.1 - 0.00028 20.8 0.0 0.00046 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Plant_NMP1 PF06694.11 EPE31002.1 - 0.17 11.0 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) DUF2034 PF10356.9 EPE31003.1 - 1.8e-30 105.8 0.0 1.6e-15 57.0 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EPE31003.1 - 1.1e-08 35.1 0.0 1.9e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Med21 PF11221.8 EPE31004.1 - 8e-50 168.8 10.7 8.9e-50 168.7 10.7 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Herpes_UL6 PF01763.16 EPE31004.1 - 0.059 11.9 1.2 0.056 12.0 1.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Spore_III_AB PF09548.10 EPE31004.1 - 0.12 12.5 4.3 0.13 12.4 3.5 1.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TMPIT PF07851.13 EPE31004.1 - 0.15 11.3 2.8 0.23 10.7 2.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Med9 PF07544.13 EPE31004.1 - 0.25 11.5 12.3 0.032 14.3 2.8 2.9 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 AAA_23 PF13476.6 EPE31004.1 - 0.25 11.8 7.5 0.28 11.7 7.5 1.2 1 0 0 1 1 1 0 AAA domain Fib_alpha PF08702.10 EPE31004.1 - 0.43 10.8 4.6 0.61 10.3 3.1 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family GAS PF13851.6 EPE31004.1 - 0.52 9.6 13.0 6.3 6.1 8.6 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Dzip-like_N PF13815.6 EPE31004.1 - 0.78 9.7 6.6 0.38 10.7 4.2 1.7 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Hydrolase PF00702.26 EPE31005.1 - 4.5e-09 36.9 0.0 3.3e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EPE31005.1 - 1.6e-08 34.8 0.1 2.3e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPE31005.1 - 0.0017 18.4 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 EPE31005.1 - 0.057 13.3 0.1 0.6 9.9 0.0 2.2 2 1 0 2 2 2 0 Acid Phosphatase Pkinase PF00069.25 EPE31007.1 - 8.3e-67 225.3 0.0 1e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE31007.1 - 6.9e-32 110.7 0.0 9e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EPE31007.1 - 5.9e-06 25.5 0.1 7.9e-06 25.1 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EPE31007.1 - 7.1e-05 22.3 0.0 0.00023 20.6 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPE31007.1 - 0.00051 20.0 0.0 0.00094 19.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EPE31007.1 - 0.002 17.5 0.0 0.05 12.9 0.0 2.2 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EPE31007.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EPE31007.1 - 0.024 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family K_channel_TID PF07941.11 EPE31008.1 - 0.0079 16.6 1.9 0.0085 16.5 1.9 1.1 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain GH131_N PF18271.1 EPE31009.1 - 4.1e-60 203.6 1.7 5.6e-60 203.2 1.7 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Polysacc_lyase PF14099.6 EPE31009.1 - 0.00089 19.2 0.8 0.0013 18.6 0.8 1.2 1 0 0 1 1 1 1 Polysaccharide lyase HIT PF01230.23 EPE31010.1 - 3.7e-22 78.9 0.1 5.3e-22 78.4 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EPE31010.1 - 2e-08 34.7 0.0 3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Mg_trans_NIPA PF05653.14 EPE31011.1 - 1.7e-91 306.4 29.7 2.3e-91 305.9 29.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EPE31011.1 - 9.6e-06 25.8 38.5 1.1e-05 25.7 7.1 3.2 3 0 0 3 3 3 2 EamA-like transporter family DUF805 PF05656.14 EPE31011.1 - 0.85 10.1 14.2 1.1 9.7 3.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Mpv17_PMP22 PF04117.12 EPE31012.1 - 2e-16 60.0 1.3 3.2e-16 59.3 0.1 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family TERT_thumb PF17984.1 EPE31012.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.3 1 1 0 1 1 1 0 Telomerase reverse transcriptase thumb DNA binding domain zf-RING_2 PF13639.6 EPE31013.1 - 3.7e-08 33.6 7.0 6.9e-08 32.7 7.0 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EPE31013.1 - 2.6e-06 27.5 4.4 5.8e-06 26.4 4.4 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 EPE31013.1 - 1.1e-05 25.4 1.1 2.4e-05 24.3 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EPE31013.1 - 5.3e-05 23.4 6.0 0.00013 22.2 6.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 EPE31013.1 - 0.002 17.7 4.3 0.004 16.8 4.3 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 EPE31013.1 - 0.012 15.5 7.4 0.023 14.6 7.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EPE31013.1 - 0.022 14.9 6.1 0.046 13.8 6.1 1.6 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.22 EPE31013.1 - 0.031 14.2 5.3 0.05 13.5 4.2 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 EPE31013.1 - 0.041 14.2 6.7 0.089 13.1 6.7 1.6 1 0 0 1 1 1 0 RING-like domain DUF3176 PF11374.8 EPE31013.1 - 0.067 13.4 0.1 0.27 11.5 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) UNC45-central PF11701.8 EPE31013.1 - 0.07 13.1 0.0 5.4 7.0 0.1 3.2 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central zf-C3HC4_2 PF13923.6 EPE31013.1 - 0.13 12.1 7.0 0.26 11.2 7.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPE31013.1 - 0.36 10.7 4.5 0.68 9.8 4.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 EPE31013.1 - 0.4 10.8 1.5 1.1 9.5 1.5 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_9 PF13901.6 EPE31013.1 - 1.5 8.8 4.8 3.8 7.4 4.8 1.6 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD PF00628.29 EPE31013.1 - 2.1 8.3 5.6 3.9 7.4 5.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 EPE31013.1 - 2.3 8.1 5.8 1.1e+02 2.7 5.7 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EPE31013.1 - 3.7 7.5 6.3 5.6 6.9 4.8 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 BUD22 PF09073.10 EPE31015.1 - 0.013 14.9 28.8 0.019 14.3 28.8 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EPE31015.1 - 0.81 9.1 31.7 1.6 8.1 31.7 1.5 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EPE31015.1 - 1.5 7.0 31.9 2.3 6.3 31.9 1.4 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 EPE31017.1 - 2e-39 135.5 0.0 3.3e-39 134.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE31017.1 - 1.2e-24 87.0 0.0 1.9e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MHC_II_alpha PF00993.20 EPE31018.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain Epimerase PF01370.21 EPE31019.1 - 4e-15 55.9 0.0 7.3e-15 55.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE31019.1 - 3.3e-10 39.4 0.0 5.9e-10 38.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EPE31019.1 - 6.7e-09 35.6 0.2 1.6e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EPE31019.1 - 3.5e-08 33.6 0.0 7.2e-08 32.5 0.1 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EPE31019.1 - 5.5e-08 32.3 0.1 9.3e-07 28.3 0.1 2.4 1 1 1 2 2 2 1 Male sterility protein NmrA PF05368.13 EPE31019.1 - 6.3e-08 32.5 0.1 1e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EPE31019.1 - 0.0004 19.6 0.1 0.00059 19.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EPE31019.1 - 0.00069 19.1 0.3 0.011 15.2 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EPE31019.1 - 0.066 12.3 0.1 0.3 10.1 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain Na_Ca_ex PF01699.24 EPE31020.1 - 2.7e-26 92.3 22.9 4.7e-14 52.6 10.1 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Otopetrin PF03189.13 EPE31020.1 - 0.0039 16.1 2.8 0.0039 16.1 2.8 1.8 2 0 0 2 2 2 1 Otopetrin DEAD PF00270.29 EPE31026.1 - 9.8e-29 100.3 0.0 1.8e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 EPE31026.1 - 1.9e-21 76.6 0.2 5.8e-21 75.0 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 EPE31026.1 - 3.8e-12 46.5 0.1 1.4e-11 44.7 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE31026.1 - 1.4e-07 31.7 0.1 2.7e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 EPE31026.1 - 3e-06 27.6 0.0 5.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like KAR9 PF08580.10 EPE31028.1 - 4.5 5.7 7.8 4.5 5.7 7.8 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 QCR10 PF09796.9 EPE31029.1 - 1.4e-30 105.1 0.7 1.8e-30 104.8 0.7 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) U-box PF04564.15 EPE31030.1 - 7.2e-23 80.5 0.0 1.5e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 EPE31030.1 - 5.4e-08 32.3 3.9 0.0014 18.4 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPE31030.1 - 8.4e-08 32.1 1.6 0.0099 16.2 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EPE31030.1 - 3.6e-07 29.7 1.1 0.00027 20.5 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 EPE31030.1 - 4.3e-07 29.6 4.9 0.0055 16.7 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPE31030.1 - 4e-06 27.3 0.3 0.026 15.0 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EPE31030.1 - 0.0023 18.6 0.5 4.6 8.3 0.4 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE31030.1 - 0.016 15.4 1.5 0.027 14.7 1.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-Nse PF11789.8 EPE31030.1 - 0.073 12.9 0.0 0.27 11.1 0.0 1.9 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit NTP_transf_9 PF04248.12 EPE31030.1 - 0.12 12.2 0.1 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF427) CHIP_TPR_N PF18391.1 EPE31030.1 - 0.44 11.3 6.9 1.4 9.8 6.9 1.9 1 1 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain TPR_6 PF13174.6 EPE31030.1 - 1.2 9.9 5.5 18 6.2 0.0 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat DIE2_ALG10 PF04922.12 EPE31031.1 - 3.8e-124 415.0 7.9 5e-124 414.6 7.9 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family RNA_pol_Rpc4 PF05132.14 EPE31031.1 - 0.12 12.8 1.0 0.21 12.0 1.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sld5 PF05916.11 EPE31032.1 - 7.3e-31 106.9 0.0 1.3e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Flu_M1_C PF08289.11 EPE31032.1 - 0.032 14.4 0.2 0.057 13.6 0.2 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Peroxin-3 PF04882.12 EPE31033.1 - 0.3 10.1 0.7 0.54 9.2 0.1 1.6 2 0 0 2 2 2 0 Peroxin-3 NMO PF03060.15 EPE31034.1 - 8.2e-57 193.1 2.2 1.2e-56 192.6 2.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EPE31034.1 - 5.8e-11 42.0 2.0 9.9e-11 41.2 2.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EPE31034.1 - 3.7e-08 32.8 2.2 6.2e-08 32.1 2.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EPE31034.1 - 0.0056 15.9 1.0 0.011 15.0 1.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 EPE31034.1 - 0.016 14.4 0.3 0.024 13.8 0.3 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Pterin_bind PF00809.22 EPE31035.1 - 4.9e-73 245.8 0.0 6.7e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EPE31035.1 - 1.3e-36 125.5 0.0 2.3e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) HET PF06985.11 EPE31036.1 - 1.4e-29 103.3 0.2 3e-29 102.3 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 EPE31037.1 - 4.1e-16 59.7 0.1 6.9e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Carla_C4 PF01623.17 EPE31038.1 - 0.45 10.5 3.9 0.21 11.6 1.2 1.8 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein Aspzincin_M35 PF14521.6 EPE31040.1 - 3.1e-06 27.8 0.1 6.4e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase R3H PF01424.22 EPE31041.1 - 7.2e-12 45.1 0.0 1.5e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 EPE31041.1 - 1.3e-05 24.9 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 EPE31041.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 Histone PF00125.24 EPE31042.1 - 1.7e-18 67.3 0.0 2.2e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EPE31042.1 - 1.1e-12 47.5 0.1 2.5e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EPE31042.1 - 3.5e-05 24.0 0.0 5.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Fungal_trans PF04082.18 EPE31043.1 - 5e-08 32.3 0.1 3.6e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE31043.1 - 3.7e-07 30.1 10.3 6.5e-07 29.4 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 EPE31044.1 - 1.7e-35 122.6 0.0 2e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE31044.1 - 4.3e-08 32.9 0.0 7e-08 32.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPE31044.1 - 3.8e-07 29.9 0.1 7.8e-07 28.9 0.1 1.8 1 1 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 EPE31044.1 - 0.00081 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 EPE31044.1 - 0.011 14.9 0.0 0.31 10.2 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein GARS_N PF02844.15 EPE31044.1 - 0.028 15.2 0.4 0.32 11.8 0.1 2.6 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain RmlD_sub_bind PF04321.17 EPE31044.1 - 0.036 13.2 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Semialdhyde_dh PF01118.24 EPE31044.1 - 0.082 13.3 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PAC2 PF09754.9 EPE31044.1 - 0.096 12.7 0.0 0.096 12.7 0.0 1.2 1 0 0 1 1 1 0 PAC2 family AAA PF00004.29 EPE31046.1 - 7.3e-12 45.8 0.0 1.7e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EPE31046.1 - 7.9e-06 25.9 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPE31046.1 - 8.2e-06 26.1 0.0 1.7e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EPE31046.1 - 3.7e-05 23.7 0.7 0.00014 21.9 0.0 2.1 3 0 0 3 3 3 1 Rad17 P-loop domain RuvB_N PF05496.12 EPE31046.1 - 5.7e-05 22.9 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EPE31046.1 - 0.0017 18.8 0.0 0.011 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EPE31046.1 - 0.0055 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EPE31046.1 - 0.0071 16.5 0.1 0.022 14.9 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPE31046.1 - 0.01 15.6 0.3 0.02 14.6 0.3 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EPE31046.1 - 0.024 14.5 0.5 0.14 12.0 0.1 2.3 1 1 1 2 2 2 0 NTPase TIP49 PF06068.13 EPE31046.1 - 0.05 12.8 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 EPE31046.1 - 0.092 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EPE31046.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EPE31046.1 - 0.12 12.9 0.4 0.56 10.7 0.1 2.2 2 0 0 2 2 2 0 ABC transporter IstB_IS21 PF01695.17 EPE31046.1 - 0.15 11.8 0.2 0.56 9.9 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.6 EPE31046.1 - 0.18 12.1 0.3 0.5 10.7 0.3 1.7 1 1 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 EPE31047.1 - 1.7e-22 79.7 0.8 2.3e-22 79.3 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_2 PF13639.6 EPE31048.1 - 1.5e-13 50.9 16.8 5.5e-13 49.0 5.9 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 EPE31048.1 - 9.3e-11 41.4 8.0 3.1e-08 33.3 1.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EPE31048.1 - 1.3e-10 40.8 2.4 1.3e-10 40.8 2.4 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EPE31048.1 - 3.3e-09 36.4 15.1 2.3e-08 33.7 5.7 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPE31048.1 - 8.4e-07 29.2 4.6 8.4e-07 29.2 4.6 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EPE31048.1 - 2e-06 27.6 3.0 2e-06 27.6 3.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EPE31048.1 - 6.5e-06 25.9 13.0 0.00024 20.9 4.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE31048.1 - 1.5e-05 24.7 10.6 0.00019 21.2 4.1 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EPE31048.1 - 6.6e-05 22.8 0.8 6.6e-05 22.8 0.8 2.9 2 1 1 3 3 3 1 RING-type zinc-finger HypA PF01155.19 EPE31048.1 - 0.0043 17.1 0.3 0.0043 17.1 0.3 2.1 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ANAPC11 PF12861.7 EPE31048.1 - 0.0064 16.5 1.5 0.0064 16.5 1.5 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_9 PF14369.6 EPE31048.1 - 0.05 13.9 6.9 0.6 10.4 4.4 2.6 2 0 0 2 2 2 0 zinc-ribbon PHD PF00628.29 EPE31048.1 - 0.14 12.1 12.6 0.17 11.8 5.1 2.6 2 0 0 2 2 2 0 PHD-finger NADH-G_4Fe-4S_3 PF10588.9 EPE31048.1 - 0.23 11.0 4.7 1 9.0 0.1 2.8 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Zn_ribbon_17 PF17120.5 EPE31048.1 - 0.26 10.9 15.9 0.19 11.4 5.4 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 EPE31048.1 - 0.27 11.1 0.3 19 5.2 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif DZR PF12773.7 EPE31048.1 - 1.2 9.3 6.2 2.2 8.3 0.6 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 EPE31048.1 - 2.4 8.4 14.9 2.9 8.1 1.8 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 EPE31048.1 - 3.2 7.9 8.4 3.6 7.7 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zinc-ribbons_6 PF07191.12 EPE31048.1 - 3.6 7.6 8.6 1.2 9.2 0.9 2.5 2 1 0 2 2 2 0 zinc-ribbons Fis1_TPR_C PF14853.6 EPE31049.1 - 3.8e-25 87.7 0.5 6.7e-25 86.9 0.5 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EPE31049.1 - 4.4e-17 61.4 0.4 1e-16 60.3 0.1 1.8 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EPE31049.1 - 0.012 15.6 1.0 0.023 14.8 1.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Bacillus_PapR PF05968.11 EPE31049.1 - 0.26 11.2 3.5 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Bacillus PapR protein Spc24 PF08286.11 EPE31050.1 - 1.9e-30 105.2 0.4 7.1e-29 100.1 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 CLZ PF16526.5 EPE31050.1 - 0.00044 20.6 5.3 0.06 13.7 0.3 2.5 2 1 0 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FPP PF05911.11 EPE31050.1 - 0.0069 14.6 2.0 0.0085 14.3 2.0 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil MAGSP PF03082.14 EPE31050.1 - 0.008 15.8 0.5 0.0096 15.6 0.5 1.1 1 0 0 1 1 1 1 Male accessory gland secretory protein BAR_3 PF16746.5 EPE31050.1 - 0.012 15.3 1.0 0.016 14.9 1.0 1.2 1 0 0 1 1 1 0 BAR domain of APPL family HMMR_N PF15905.5 EPE31050.1 - 0.016 14.7 1.6 0.02 14.4 1.6 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal WDCP PF15390.6 EPE31050.1 - 0.019 13.4 1.4 0.022 13.2 1.4 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF5082 PF16888.5 EPE31050.1 - 0.032 14.5 2.0 0.054 13.8 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 EPE31050.1 - 0.033 14.7 5.8 0.048 14.2 5.8 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Ax_dynein_light PF10211.9 EPE31050.1 - 0.11 12.5 3.3 0.16 11.9 1.0 1.9 1 1 1 2 2 2 0 Axonemal dynein light chain Prefoldin_2 PF01920.20 EPE31050.1 - 0.12 12.4 2.4 0.68 9.9 0.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit SlyX PF04102.12 EPE31050.1 - 0.15 12.7 3.0 0.5 11.0 0.6 2.3 1 1 1 2 2 2 0 SlyX Uso1_p115_C PF04871.13 EPE31050.1 - 0.31 11.4 6.2 0.52 10.7 6.2 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF724 PF05266.14 EPE31050.1 - 0.37 10.6 2.3 1.2 8.9 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.12 EPE31050.1 - 0.72 9.9 9.2 2.3 8.3 9.2 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 EPE31050.1 - 0.89 10.0 2.4 46 4.5 0.2 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Hsk3 PF08227.11 EPE31050.1 - 2 8.8 11.6 0.13 12.7 1.8 2.5 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DUF1690 PF07956.11 EPE31050.1 - 4.6 7.7 7.7 31 5.0 7.7 2.0 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) XhlA PF10779.9 EPE31050.1 - 8.8 6.6 6.1 30 4.9 0.6 2.4 1 1 2 3 3 3 0 Haemolysin XhlA TatD_DNase PF01026.21 EPE31052.1 - 4.5e-31 108.2 0.0 7.2e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase Myb_DNA-binding PF00249.31 EPE31053.1 - 0.051 13.8 0.3 0.25 11.6 0.2 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPE31053.1 - 0.078 13.2 0.0 0.82 10.0 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Ribosomal_S2 PF00318.20 EPE31053.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 SNF2_N PF00176.23 EPE31054.1 - 3.1e-61 207.0 0.8 6.4e-61 206.0 0.5 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE31054.1 - 2.5e-21 76.1 0.0 1e-20 74.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE31054.1 - 4.5e-07 30.0 0.3 3.7e-06 27.1 0.0 2.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EPE31054.1 - 9.4e-06 25.0 0.0 9.4e-06 25.0 0.0 2.2 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 EPE31054.1 - 0.00016 21.0 4.7 0.00017 20.8 0.0 3.0 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 EPE31054.1 - 0.0034 17.1 0.0 0.0034 17.1 0.0 2.4 3 0 0 3 3 3 1 SWI2/SNF2 ATPase SecG PF03840.14 EPE31055.1 - 0.059 13.5 0.2 0.098 12.8 0.2 1.3 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Coq4 PF05019.13 EPE31056.1 - 0.12 11.7 0.1 5 6.4 0.0 2.0 1 1 1 2 2 2 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Trp_oprn_chp PF09534.10 EPE31057.1 - 0.011 15.6 0.2 0.019 14.8 0.2 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MGC-24 PF05283.11 EPE31057.1 - 0.035 14.5 2.5 0.035 14.5 2.5 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Stevor PF17410.2 EPE31058.1 - 0.0019 17.8 0.1 0.0028 17.3 0.1 1.2 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame DUF5305 PF17231.2 EPE31058.1 - 0.022 14.2 0.2 0.034 13.6 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Adeno_E3_CR2 PF02439.15 EPE31058.1 - 0.15 11.8 0.3 0.3 10.9 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RIFIN PF02009.16 EPE31058.1 - 0.27 11.1 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Rifin MGC-24 PF05283.11 EPE31058.1 - 0.48 10.9 5.9 0.093 13.2 1.0 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SKG6 PF08693.10 EPE31058.1 - 0.93 9.0 4.5 2.1 7.9 4.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain WSC PF01822.19 EPE31060.1 - 2.3e-40 136.6 70.5 8.1e-10 38.8 3.8 6.2 6 0 0 6 6 6 5 WSC domain LCM PF04072.14 EPE31060.1 - 2.2e-18 66.9 0.0 5.3e-18 65.6 0.0 1.7 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Glyco_hydro_16 PF00722.21 EPE31060.1 - 0.00016 21.2 0.0 0.00063 19.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SUN PF03856.13 EPE31061.1 - 1.4e-80 270.3 12.7 2.1e-80 269.7 12.7 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Trypan_PARP PF05887.11 EPE31061.1 - 0.098 12.6 5.2 0.19 11.7 5.2 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SPX PF03105.19 EPE31061.1 - 4.5 7.1 26.3 7.8 6.3 26.3 1.4 1 0 0 1 1 1 0 SPX domain HSBP1 PF06825.12 EPE31062.1 - 0.00071 19.4 0.7 0.032 14.1 0.0 3.7 3 0 0 3 3 3 1 Heat shock factor binding protein 1 NPV_P10 PF05531.12 EPE31062.1 - 0.049 14.1 29.1 0.6 10.6 0.1 8.2 6 2 2 9 9 9 0 Nucleopolyhedrovirus P10 protein Matrilin_ccoil PF10393.9 EPE31062.1 - 6.7 6.7 7.4 2.4 8.1 0.5 3.5 3 1 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Lectin_N PF03954.14 EPE31062.1 - 7.6 6.3 25.6 1.1 9.0 1.0 5.8 5 2 1 6 6 6 0 Hepatic lectin, N-terminal domain Csm1_N PF18504.1 EPE31063.1 - 0.068 13.5 0.3 0.068 13.5 0.3 3.7 3 1 1 4 4 4 0 Csm1 N-terminal domain DUF4644 PF15486.6 EPE31063.1 - 1.1 9.0 4.3 0.25 11.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4644) Macoilin PF09726.9 EPE31063.1 - 1.3 7.5 19.1 2.6 6.5 19.1 1.5 1 0 0 1 1 1 0 Macoilin family ATG16 PF08614.11 EPE31065.1 - 0.00021 21.6 0.6 0.00021 21.6 0.6 1.9 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) ZapB PF06005.12 EPE31065.1 - 0.58 10.6 5.2 2.4 8.7 4.6 2.3 2 1 0 2 2 2 0 Cell division protein ZapB Ion_trans_2 PF07885.16 EPE31066.1 - 2.1e-28 98.1 24.0 1.2e-16 60.5 3.9 3.0 3 0 0 3 3 3 2 Ion channel SKN1 PF03935.15 EPE31067.1 - 4.8e-223 741.1 0.3 5.6e-223 740.9 0.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF3716 PF12511.8 EPE31068.1 - 8.9e-11 41.7 6.6 1.3e-10 41.1 6.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Med3 PF11593.8 EPE31068.1 - 7e-05 22.2 0.7 0.0001 21.7 0.7 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Mit_KHE1 PF10173.9 EPE31069.1 - 4.5e-63 212.8 0.6 5.1e-63 212.6 0.0 1.4 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related MARVEL PF01284.23 EPE31070.1 - 0.013 15.5 0.6 0.022 14.8 0.6 1.3 1 0 0 1 1 1 0 Membrane-associating domain DUF588 PF04535.12 EPE31070.1 - 0.021 14.6 0.1 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF588) Cupin_2 PF07883.11 EPE31071.1 - 5.8e-06 25.9 0.2 1e-05 25.2 0.2 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EPE31071.1 - 3.5e-05 23.5 0.1 5e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 EPE31071.1 - 0.0013 18.5 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 EPE31071.1 - 0.038 14.2 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cullin PF00888.22 EPE31072.1 - 4e-192 640.1 12.6 5.5e-192 639.7 12.6 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EPE31072.1 - 1.2e-24 86.1 3.5 1.2e-24 86.1 3.5 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain Erf4 PF10256.9 EPE31072.1 - 0.15 12.2 1.8 1.3 9.1 0.2 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family AnfG_VnfG PF03139.15 EPE31072.1 - 0.18 11.9 3.4 0.64 10.1 0.9 2.8 2 0 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit OB_MalK PF17912.1 EPE31073.1 - 0.076 13.9 0.0 0.13 13.1 0.0 1.6 1 1 0 1 1 1 0 MalK OB fold domain G-alpha PF00503.20 EPE31074.1 - 2e-113 379.1 0.1 2.4e-113 378.9 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EPE31074.1 - 2e-15 56.7 0.9 3.1e-10 39.8 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EPE31074.1 - 0.00027 20.4 0.3 0.21 10.9 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EPE31074.1 - 0.0047 17.1 0.1 0.92 9.7 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EPE31074.1 - 0.1 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 EPE31074.1 - 0.12 11.4 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 MCM P-loop domain Phosphorylase PF00343.20 EPE31075.1 - 0 1054.9 0.0 0 1054.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase GATA PF00320.27 EPE31076.1 - 3.4e-14 52.2 2.4 6.6e-14 51.2 2.4 1.5 1 0 0 1 1 1 1 GATA zinc finger ATG16 PF08614.11 EPE31076.1 - 0.0012 19.1 7.1 0.0029 17.9 7.1 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DegS PF05384.11 EPE31076.1 - 0.0093 15.5 6.2 0.018 14.5 6.2 1.5 1 1 0 1 1 1 1 Sensor protein DegS Pox_A_type_inc PF04508.12 EPE31076.1 - 0.032 14.1 4.4 11 6.1 3.2 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DivIVA PF05103.13 EPE31076.1 - 0.036 14.1 5.1 0.062 13.4 5.1 1.4 1 0 0 1 1 1 0 DivIVA protein DHR10 PF18595.1 EPE31076.1 - 0.048 13.7 11.8 0.071 13.2 11.8 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Tropomyosin PF00261.20 EPE31076.1 - 0.076 12.4 10.1 0.1 11.9 10.1 1.1 1 0 0 1 1 1 0 Tropomyosin DUF745 PF05335.13 EPE31076.1 - 0.31 10.7 1.8 0.5 10.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) BRE1 PF08647.11 EPE31076.1 - 0.4 10.8 6.2 0.78 9.9 6.2 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase ADIP PF11559.8 EPE31076.1 - 0.76 9.8 11.2 1.4 9.0 8.0 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 EPE31076.1 - 1.2 8.0 8.6 1.6 7.5 8.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PRKG1_interact PF15898.5 EPE31076.1 - 1.5 9.8 11.1 0.46 11.4 2.3 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Atg14 PF10186.9 EPE31076.1 - 1.7 7.6 6.6 3.1 6.8 6.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KH_8 PF17903.1 EPE31077.1 - 4e-30 103.7 0.0 9.2e-30 102.6 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EPE31077.1 - 0.043 13.6 0.0 0.38 10.6 0.0 2.5 1 1 1 2 2 2 0 KH domain DUF4746 PF15928.5 EPE31077.1 - 0.8 9.1 14.5 1.1 8.6 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Fungal_trans PF04082.18 EPE31078.1 - 6.6e-06 25.4 0.0 1.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE31078.1 - 0.076 13.2 1.0 0.16 12.1 1.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain KH_1 PF00013.29 EPE31079.1 - 1.7e-32 111.0 4.3 1.4e-06 28.0 0.0 7.6 8 0 0 8 8 8 6 KH domain ResIII PF04851.15 EPE31082.1 - 1.3e-26 93.6 0.0 8.4e-26 91.0 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EPE31082.1 - 3.1e-16 59.7 0.0 1.3e-13 51.2 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 EPE31082.1 - 5.4e-12 45.8 0.0 1.1e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EPE31082.1 - 6.7e-07 29.2 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase UvrD-helicase PF00580.21 EPE31082.1 - 0.00021 20.9 1.5 0.08 12.4 0.0 3.1 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 EPE31082.1 - 0.0022 17.3 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EPE31082.1 - 0.055 13.7 0.0 0.19 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 EPE31082.1 - 0.081 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SWIRM PF04433.17 EPE31084.1 - 2.3e-31 108.0 0.1 4.4e-31 107.1 0.1 1.5 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EPE31084.1 - 1.5e-30 105.0 3.8 3.7e-30 103.7 3.8 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EPE31084.1 - 1.2e-09 38.2 0.0 3.2e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPE31084.1 - 2.4e-06 27.7 0.1 5.6e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EPE31084.1 - 0.14 12.4 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 DUF3439 PF11921.8 EPE31084.1 - 0.24 11.3 6.5 0.56 10.2 6.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) ETF PF01012.21 EPE31085.1 - 5.4e-41 140.5 1.3 8.9e-41 139.8 1.3 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EPE31085.1 - 1.5e-32 111.4 0.3 3e-32 110.5 0.3 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Pyr_redox_2 PF07992.14 EPE31086.1 - 1.9e-05 24.1 0.1 0.00019 20.8 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Ploopntkinase1 PF18748.1 EPE31086.1 - 0.036 13.6 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 MutL_C PF08676.11 EPE31088.1 - 3.9e-24 85.1 0.0 1e-23 83.8 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EPE31088.1 - 1.1e-18 67.1 0.0 3.6e-18 65.4 0.0 1.9 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EPE31088.1 - 2.9e-13 49.8 0.1 8.3e-13 48.3 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EPE31088.1 - 6.9e-07 29.8 0.1 3.9e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cys_Met_Meta_PP PF01053.20 EPE31089.1 - 6.8e-138 459.3 0.0 8e-138 459.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EPE31089.1 - 1.7e-06 27.5 0.0 2.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPE31089.1 - 1.5e-05 24.2 0.0 3.7e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EPE31089.1 - 0.00017 20.3 0.1 0.00074 18.2 0.1 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 EPE31089.1 - 0.0002 20.8 0.0 0.0011 18.4 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EPE31089.1 - 0.094 12.0 0.1 0.38 10.0 0.1 1.9 1 1 0 1 1 1 0 Beta-eliminating lyase WW PF00397.26 EPE31090.1 - 0.00046 20.2 2.3 0.0011 19.0 2.3 1.7 1 0 0 1 1 1 1 WW domain GGACT PF06094.12 EPE31091.1 - 1.3e-08 35.5 0.0 2.7e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 EPE31091.1 - 2e-05 24.9 0.0 0.00069 20.0 0.0 2.3 2 0 0 2 2 2 1 AIG2-like family HSP20 PF00011.21 EPE31092.1 - 1.9e-13 50.4 0.0 2.2e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EPE31092.1 - 0.064 12.8 0.1 5.4 6.7 0.0 2.9 3 0 0 3 3 3 0 HSP20-like domain found in ArsA SH3_9 PF14604.6 EPE31093.1 - 1.1e-10 41.2 0.0 1.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EPE31093.1 - 1.4e-07 31.0 0.0 2.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EPE31093.1 - 3.2e-06 26.7 0.0 5.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF4690 PF15756.5 EPE31093.1 - 4.4e-05 24.0 3.2 4.4e-05 24.0 3.2 2.9 4 0 0 4 4 4 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 EPE31093.1 - 0.0085 16.2 12.1 0.037 14.1 12.2 2.1 1 1 0 1 1 1 1 Podoplanin CYYR1 PF10873.8 EPE31093.1 - 0.05 14.1 0.0 0.05 14.1 0.0 2.9 3 1 1 4 4 4 0 Cysteine and tyrosine-rich protein 1 Amnionless PF14828.6 EPE31093.1 - 0.057 12.2 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Amnionless EphA2_TM PF14575.6 EPE31093.1 - 0.077 13.9 0.0 0.16 12.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.18 EPE31093.1 - 0.089 13.0 2.4 0.12 12.6 0.1 2.4 2 0 0 2 2 2 0 Glycophorin A TMEM154 PF15102.6 EPE31093.1 - 0.93 9.4 7.7 0.055 13.4 1.7 2.1 2 1 0 2 2 2 0 TMEM154 protein family FSA_C PF10479.9 EPE31094.1 - 8.1 4.4 9.4 10 4.1 9.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus ATG22 PF11700.8 EPE31095.1 - 9e-179 595.1 22.7 1e-178 594.9 22.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EPE31095.1 - 1.7e-05 23.9 45.5 0.0054 15.7 4.6 3.5 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF3425 PF11905.8 EPE31096.1 - 3e-20 72.4 0.0 5.2e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) RTA1 PF04479.13 EPE31097.1 - 1.6e-62 210.8 10.4 1.6e-62 210.8 10.4 1.6 2 0 0 2 2 2 1 RTA1 like protein Glyco_hydro_61 PF03443.14 EPE31098.1 - 5.9e-67 225.6 0.0 8.2e-67 225.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 zf-C2H2_11 PF16622.5 EPE31099.1 - 0.0068 16.2 0.4 0.016 15.0 0.4 1.6 1 0 0 1 1 1 1 zinc-finger C2H2-type Lipase_GDSL PF00657.22 EPE31101.1 - 2.9e-10 40.4 0.0 4.1e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EPE31101.1 - 0.0014 19.1 2.7 0.0049 17.3 2.7 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FAD_binding_3 PF01494.19 EPE31102.1 - 3.1e-47 161.5 0.0 4.1e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPE31102.1 - 1.2e-06 28.3 0.1 0.047 13.3 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EPE31102.1 - 1.1e-05 24.7 0.2 4.6e-05 22.7 0.2 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EPE31102.1 - 1.3e-05 24.6 1.7 0.0016 17.8 0.9 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE31102.1 - 1.8e-05 24.0 0.1 0.0042 16.2 0.8 2.1 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EPE31102.1 - 2.1e-05 24.7 0.8 5.7e-05 23.3 0.4 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EPE31102.1 - 3.3e-05 22.8 0.4 0.00049 18.9 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EPE31102.1 - 4.7e-05 22.8 0.1 0.009 15.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE31102.1 - 0.00051 19.4 0.1 0.00087 18.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EPE31102.1 - 0.00095 18.6 1.4 0.0072 15.7 1.4 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EPE31102.1 - 0.0055 16.1 0.8 0.022 14.1 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EPE31102.1 - 0.007 16.9 0.0 0.62 10.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPE31102.1 - 0.034 14.1 0.4 6.6 6.7 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 EPE31102.1 - 0.043 12.9 0.1 0.066 12.3 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 EPE31102.1 - 0.11 11.3 0.3 3.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 EPE31102.1 - 0.16 11.6 0.2 0.27 10.8 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 EPE31103.1 - 1.1e-20 73.9 0.0 1.3e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE31103.1 - 1.3e-16 60.9 0.0 1.8e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE31103.1 - 1.3e-09 38.2 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EPE31103.1 - 0.003 17.0 0.0 0.0063 15.9 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EPE31103.1 - 0.02 14.8 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding zf-C2HC_2 PF13913.6 EPE31104.1 - 0.00016 21.5 1.7 0.00016 21.5 1.7 1.8 2 0 0 2 2 2 1 zinc-finger of a C2HC-type Cupin_8 PF13621.6 EPE31110.1 - 7.7e-40 137.2 0.1 1.4e-39 136.3 0.1 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EPE31110.1 - 3.1e-08 33.5 0.0 1.7e-06 27.8 0.0 2.5 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EPE31110.1 - 0.062 13.7 0.0 0.52 10.8 0.0 2.2 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 EPE31110.1 - 0.11 12.3 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Cupin domain Reticulon PF02453.17 EPE31111.1 - 1.2e-33 116.3 7.0 1.8e-33 115.7 7.0 1.3 1 0 0 1 1 1 1 Reticulon DUF3563 PF12086.8 EPE31111.1 - 0.092 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) DUF883 PF05957.13 EPE31111.1 - 0.19 12.4 2.1 1.1 9.9 0.5 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) FUSC_2 PF13515.6 EPE31111.1 - 0.56 10.3 9.3 1.8 8.7 1.5 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein-like ApoO PF09769.9 EPE31111.1 - 0.81 9.7 6.5 4.7 7.2 0.3 2.7 2 1 0 2 2 2 0 Apolipoprotein O COesterase PF00135.28 EPE31114.1 - 1.1e-90 304.9 0.0 1.3e-90 304.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE31114.1 - 0.0015 18.4 0.1 0.0096 15.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold GST_N_3 PF13417.6 EPE31116.1 - 4.1e-15 55.9 0.1 8.9e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPE31116.1 - 1.3e-12 47.8 0.0 2.4e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EPE31116.1 - 1.4e-10 41.3 0.0 2.7e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPE31116.1 - 0.00049 20.1 0.0 0.00086 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EPE31116.1 - 0.018 15.3 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Rpn3_C PF08375.11 EPE31116.1 - 0.077 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal HET PF06985.11 EPE31118.1 - 2.9e-28 99.1 0.1 6.4e-28 97.9 0.1 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 EPE31119.1 - 9.8e-31 107.1 0.1 1.6e-30 106.4 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GTP1_OBG PF01018.22 EPE31120.1 - 1.2e-38 132.2 2.5 1.2e-28 99.6 3.7 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EPE31120.1 - 1.3e-23 83.2 0.0 2.5e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPE31120.1 - 3.2e-07 30.0 0.0 7.4e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_33 PF13671.6 EPE31120.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EPE31120.1 - 0.061 13.9 0.0 0.59 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EPE31120.1 - 0.061 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 EPE31120.1 - 0.063 12.2 0.0 0.68 8.9 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 EPE31120.1 - 0.22 10.9 0.0 0.61 9.5 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family HsbA PF12296.8 EPE31122.1 - 0.00031 21.2 5.7 0.4 11.1 0.1 3.9 2 1 2 4 4 4 2 Hydrophobic surface binding protein A BSD PF03909.17 EPE31122.1 - 0.58 10.2 6.0 3.2 7.8 0.0 3.4 3 1 1 4 4 4 0 BSD domain YtkA PF13115.6 EPE31122.1 - 0.66 10.6 5.7 0.73 10.5 2.7 2.6 2 0 0 2 2 2 0 YtkA-like Exonuc_VII_L PF02601.15 EPE31122.1 - 4 6.9 22.8 0.72 9.4 0.2 3.0 2 1 1 3 3 3 0 Exonuclease VII, large subunit CorA PF01544.18 EPE31122.1 - 4.2 6.6 5.4 6.6 6.0 4.6 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein RNA_pol_Rpb5_C PF01191.19 EPE31123.1 - 7.4e-34 115.4 0.4 2.5e-33 113.7 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EPE31123.1 - 7.1e-25 87.4 0.0 1.1e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EPE31123.1 - 0.036 14.1 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease MFS_1 PF07690.16 EPE31124.1 - 1.8e-36 125.8 33.3 1.8e-36 125.8 33.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE31124.1 - 1.9e-05 23.7 14.9 1.9e-05 23.7 14.9 2.6 2 2 0 2 2 2 1 Sugar (and other) transporter AMP-binding PF00501.28 EPE31125.1 - 2.3e-84 283.4 0.2 2.9e-84 283.1 0.2 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE31125.1 - 5.4e-13 49.7 1.6 7.9e-13 49.2 0.8 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Methyltr_RsmB-F PF01189.17 EPE31126.1 - 2.6e-32 112.1 0.0 3.6e-25 88.8 0.0 2.7 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FeS_assembly_P PF01883.19 EPE31126.1 - 0.14 12.4 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein Aldolase_II PF00596.21 EPE31127.1 - 2.9e-47 161.0 0.1 3.8e-47 160.6 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain p450 PF00067.22 EPE31128.1 - 5.5e-33 114.4 0.0 7.2e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flagellin_N PF00669.20 EPE31129.1 - 0.084 13.0 0.3 0.084 13.0 0.3 1.7 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region FlaC_arch PF05377.11 EPE31129.1 - 6.9 7.1 8.6 0.2 12.1 0.3 2.9 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) GM_CSF PF01109.17 EPE31130.1 - 0.016 15.3 0.1 0.035 14.3 0.1 1.6 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Cep57_CLD PF14073.6 EPE31130.1 - 0.06 13.4 13.0 0.11 12.5 13.0 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 TSP_NTD PF17804.1 EPE31130.1 - 0.85 9.8 7.6 1.6 8.9 7.6 1.5 1 1 0 1 1 1 0 Tail specific protease N-terminal domain CDC45 PF02724.14 EPE31132.1 - 9.7e-250 830.3 2.8 2.9e-248 825.4 2.8 2.9 1 1 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 EPE31132.1 - 0.059 12.8 25.0 0.38 10.1 4.8 2.2 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 EPE31132.1 - 0.75 9.1 33.3 1 8.6 6.6 2.2 2 0 0 2 2 2 0 BUD22 PNISR PF15996.5 EPE31132.1 - 2.5 8.3 26.3 6.9 6.9 1.4 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR FAM60A PF15396.6 EPE31132.1 - 3 7.8 11.9 0.053 13.5 2.8 2.0 2 0 0 2 2 2 0 Protein Family FAM60A SAPS PF04499.15 EPE31132.1 - 3.7 6.2 6.3 0.68 8.7 0.2 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 EPE31132.1 - 4.1 5.5 29.5 1 7.5 14.4 2.1 2 0 0 2 2 2 0 Nop14-like family HET PF06985.11 EPE31133.1 - 1.7e-29 103.0 0.4 5.1e-27 95.0 0.4 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CHAT PF12770.7 EPE31134.1 - 8.6e-35 120.5 0.0 1.2e-34 120.1 0.0 1.2 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EPE31134.1 - 0.1 12.5 0.4 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPE31135.1 - 1.3e-08 34.5 19.7 6.7e-05 22.6 1.6 7.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 EPE31135.1 - 0.0018 18.5 19.0 0.43 10.9 0.5 5.4 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPE31135.1 - 0.044 14.2 10.1 5 7.7 0.2 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 EPE31135.1 - 0.65 9.7 16.9 2.5 7.9 0.4 7.0 7 1 0 7 7 7 0 TPR repeat TPR_8 PF13181.6 EPE31135.1 - 1.3 9.5 8.8 17 6.0 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat adh_short PF00106.25 EPE31137.1 - 6.6e-10 38.8 0.0 1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE31137.1 - 6.8e-06 25.8 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE31137.1 - 1.1e-05 25.4 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF2183 PF09949.9 EPE31138.1 - 1e-33 115.6 0.0 2.2e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) MFS_1 PF07690.16 EPE31138.1 - 2.9e-32 112.0 30.3 2.9e-32 112.0 30.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE31138.1 - 4.6e-22 78.5 2.3 4.6e-22 78.5 2.3 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter TMEM100 PF16311.5 EPE31138.1 - 0.34 10.5 1.3 0.71 9.5 1.3 1.5 1 0 0 1 1 1 0 Transmembrane protein 100 F-box-like PF12937.7 EPE31139.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like PSII PF00421.19 EPE31139.1 - 0.21 10.2 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Photosystem II protein Glyco_hydro_18 PF00704.28 EPE31140.1 - 1.8e-49 169.2 1.5 2.7e-49 168.6 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EPE31140.1 - 6.6e-08 32.5 0.0 0.013 15.6 0.1 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 EPE31140.1 - 0.00092 19.6 8.2 0.00092 19.6 8.2 3.3 3 0 0 3 3 3 1 Chitin recognition protein COE1_DBD PF16422.5 EPE31140.1 - 0.15 11.5 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain Phage-MuB_C PF09077.11 EPE31140.1 - 0.2 11.6 0.1 0.54 10.2 0.1 1.7 1 0 0 1 1 1 0 Mu B transposition protein, C terminal DnaJ PF00226.31 EPE31142.1 - 3e-21 75.3 0.6 2e-20 72.7 0.8 2.3 2 0 0 2 2 2 1 DnaJ domain Fungal_trans_2 PF11951.8 EPE31143.1 - 7.6e-38 130.3 0.0 1e-37 129.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE31143.1 - 1.8e-06 27.9 12.4 1.8e-06 27.9 12.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_gp2 PF05955.11 EPE31143.1 - 0.19 11.3 0.2 0.3 10.6 0.2 1.2 1 0 0 1 1 1 0 Equine herpesvirus glycoprotein gp2 Dioxygenase_C PF00775.21 EPE31144.1 - 7.7e-46 155.8 0.0 9.9e-46 155.5 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EPE31144.1 - 3.5e-24 84.4 0.1 7e-24 83.5 0.1 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EPE31144.1 - 1.8e-05 24.9 0.0 0.00027 21.1 0.0 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain FAD_binding_3 PF01494.19 EPE31145.1 - 1.7e-85 287.4 0.0 3.6e-85 286.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EPE31145.1 - 3.6e-53 180.0 0.0 6.3e-53 179.2 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 EPE31145.1 - 1e-05 24.8 0.2 2.1e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EPE31145.1 - 3.5e-05 22.7 0.2 5.4e-05 22.1 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EPE31145.1 - 9.8e-05 21.7 0.2 0.00023 20.5 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE31145.1 - 0.0004 19.7 0.1 0.002 17.4 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EPE31145.1 - 0.0013 18.1 0.2 0.0021 17.5 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EPE31145.1 - 0.0014 17.8 0.2 0.0023 17.1 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EPE31145.1 - 0.0015 18.7 0.0 0.015 15.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EPE31145.1 - 0.0016 17.7 0.2 0.0024 17.2 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EPE31145.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EPE31145.1 - 0.044 12.8 0.1 0.087 11.9 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 EPE31145.1 - 0.076 12.6 0.1 0.2 11.2 0.1 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.10 EPE31145.1 - 0.079 12.0 0.0 0.87 8.6 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Trp_halogenase PF04820.14 EPE31145.1 - 0.083 11.7 1.2 0.83 8.4 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Abhydrolase_1 PF00561.20 EPE31146.1 - 2.7e-24 86.2 0.0 3.1e-21 76.2 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE31146.1 - 3.7e-22 78.8 0.0 2.3e-21 76.1 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPE31146.1 - 3.2e-21 77.0 0.1 4.8e-21 76.4 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EPE31146.1 - 1.8e-07 30.9 0.0 0.0064 16.1 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 EPE31146.1 - 1.5e-06 28.0 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EPE31146.1 - 6.1e-05 22.9 0.1 0.00012 21.9 0.1 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.16 EPE31146.1 - 0.00012 22.0 0.0 3.7 7.3 0.0 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Ndr PF03096.14 EPE31146.1 - 0.0003 19.6 0.0 0.00042 19.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 EPE31146.1 - 0.00052 20.2 0.0 0.00074 19.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 EPE31146.1 - 0.0014 18.5 0.1 0.0024 17.7 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF1057 PF06342.12 EPE31146.1 - 0.0019 17.3 0.0 0.0026 16.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.13 EPE31146.1 - 0.0024 17.7 0.2 0.0053 16.6 0.1 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 EPE31146.1 - 0.0031 16.1 0.0 0.1 11.1 0.0 2.1 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II DUF676 PF05057.14 EPE31146.1 - 0.0032 17.0 0.0 0.006 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 EPE31146.1 - 0.0034 17.3 0.1 0.0089 15.9 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase BAAT_C PF08840.11 EPE31146.1 - 0.0059 16.5 0.0 0.055 13.4 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.11 EPE31146.1 - 0.0086 15.4 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF1598 PF07643.11 EPE31146.1 - 0.0095 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1598) AXE1 PF05448.12 EPE31146.1 - 0.018 13.7 0.2 0.037 12.7 0.2 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Acyl_transf_1 PF00698.21 EPE31146.1 - 0.039 13.5 0.2 0.065 12.7 0.2 1.3 1 0 0 1 1 1 0 Acyl transferase domain Esterase PF00756.20 EPE31146.1 - 0.046 13.3 0.6 0.094 12.3 0.2 1.7 1 1 1 2 2 2 0 Putative esterase Peptidase_S9 PF00326.21 EPE31146.1 - 0.061 12.8 0.0 10 5.5 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family UPF0227 PF05728.12 EPE31146.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Chlorophyllase2 PF12740.7 EPE31146.1 - 0.091 11.7 0.5 0.71 8.7 0.5 2.1 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_8 PF06259.12 EPE31146.1 - 0.097 12.3 0.7 0.39 10.3 0.1 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase Pro_CA PF00484.19 EPE31146.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Carbonic anhydrase BRX_N PF13713.6 EPE31147.1 - 0.067 13.0 0.7 0.18 11.6 0.7 1.8 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Ank_2 PF12796.7 EPE31148.1 - 2.3e-50 169.1 2.8 1.1e-13 51.6 0.0 6.2 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE31148.1 - 1.2e-35 121.4 7.4 1.1e-09 38.7 0.0 8.4 3 1 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE31148.1 - 1.5e-34 114.1 3.6 0.0078 16.6 0.0 11.1 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 EPE31148.1 - 2e-30 104.4 3.9 8.1e-10 38.8 0.1 6.7 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EPE31148.1 - 3.1e-29 100.1 10.1 0.00023 21.5 0.0 10.7 10 0 0 10 10 10 7 Ankyrin repeat NACHT PF05729.12 EPE31148.1 - 1.4e-10 41.4 0.3 1.5e-09 38.0 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EPE31148.1 - 0.0011 19.3 0.1 0.0011 19.3 0.1 2.6 3 0 0 3 3 2 1 AAA ATPase domain AAA_14 PF13173.6 EPE31148.1 - 0.0012 18.8 0.0 0.0034 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPE31148.1 - 0.038 13.7 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EPE31148.1 - 0.042 14.1 0.1 0.27 11.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EPE31148.1 - 0.066 13.4 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain Bunya_G2 PF03563.13 EPE31148.1 - 0.096 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 LBR_tudor PF09465.10 EPE31149.1 - 0.092 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain NAD_binding_8 PF13450.6 EPE31150.1 - 3.8e-10 39.8 0.0 9.3e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EPE31150.1 - 2e-07 30.5 0.0 1.8e-05 24.1 0.0 3.1 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 EPE31150.1 - 9.7e-07 27.6 0.0 7.1e-06 24.7 0.1 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EPE31150.1 - 4.3e-06 26.2 0.0 0.00044 19.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE31150.1 - 6.5e-06 25.6 0.0 3.4e-05 23.3 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPE31150.1 - 0.0003 20.8 0.1 0.0013 18.7 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EPE31150.1 - 0.018 14.3 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EPE31150.1 - 0.1 11.3 0.1 0.19 10.4 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Peptidase_S10 PF00450.22 EPE31151.1 - 3.3e-102 343.0 0.0 4.3e-102 342.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Chlorophyllase2 PF12740.7 EPE31152.1 - 4.1e-09 35.7 0.0 5.9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EPE31152.1 - 4.4e-06 25.9 0.0 6.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase PAF-AH_p_II PF03403.13 EPE31152.1 - 4.6e-05 22.1 0.0 0.014 13.9 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.13 EPE31152.1 - 0.08 12.8 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 EPE31152.1 - 0.082 12.4 0.0 0.23 11.0 0.0 1.6 1 1 1 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EPE31152.1 - 0.083 12.1 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 HET PF06985.11 EPE31153.1 - 3.1e-19 69.8 0.0 6.5e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF934 PF06073.12 EPE31153.1 - 0.059 13.3 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF934) GBV-C_env PF12786.7 EPE31153.1 - 0.073 11.7 0.2 0.12 11.1 0.2 1.2 1 0 0 1 1 1 0 GB virus C genotype envelope Bacteriocin_IIi PF11758.8 EPE31153.1 - 0.15 11.9 0.4 0.52 10.2 0.4 1.9 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin HET PF06985.11 EPE31154.1 - 5.7e-27 94.9 2.8 1.2e-26 93.9 0.7 2.4 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) SPACA7 PF15307.6 EPE31154.1 - 0.037 14.3 2.7 2.3 8.5 0.2 2.4 1 1 1 2 2 2 0 Sperm acrosome-associated protein 7 p450 PF00067.22 EPE31155.1 - 4.7e-50 170.7 0.0 6.1e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DSPc PF00782.20 EPE31157.1 - 2.2e-14 53.4 0.2 5.3e-14 52.2 0.2 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EPE31157.1 - 0.00055 20.2 0.1 0.00091 19.5 0.1 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EPE31157.1 - 0.093 12.3 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MFS_1 PF07690.16 EPE31158.1 - 4.8e-12 45.5 31.9 8.4e-12 44.7 31.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EPE31158.1 - 6.9e-10 38.9 9.8 6.9e-10 38.9 9.8 4.0 3 1 2 5 5 5 1 Ion channel regulatory protein UNC-93 End3 PF12761.7 EPE31159.1 - 5.5e-77 258.4 2.0 7.2e-77 258.1 2.0 1.1 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 EPE31159.1 - 2e-51 172.2 0.0 2.5e-49 165.5 0.0 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EPE31159.1 - 4.1e-08 32.2 0.9 2.1e-07 30.0 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EPE31159.1 - 2.9e-07 30.8 0.2 3.9e-06 27.2 0.0 2.7 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 EPE31159.1 - 4.2e-05 23.3 0.1 0.0018 18.1 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EPE31159.1 - 0.00038 20.2 1.2 0.0015 18.3 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EPE31159.1 - 0.0072 15.8 1.3 0.018 14.6 0.2 2.3 2 0 0 2 2 2 1 EF hand Phage_GP20 PF06810.11 EPE31159.1 - 0.31 10.8 3.1 5.5 6.8 0.2 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 FlaC_arch PF05377.11 EPE31159.1 - 0.44 11.0 2.8 3.6 8.1 0.2 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Csm1_N PF18504.1 EPE31159.1 - 6.3 7.2 10.2 6.8 7.1 1.0 3.0 3 0 0 3 3 3 0 Csm1 N-terminal domain Ax_dynein_light PF10211.9 EPE31159.1 - 6.5 6.6 8.0 24 4.8 0.6 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain DUF5446 PF17522.2 EPE31159.1 - 7.4 6.8 6.1 1.9 8.7 0.3 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5446) HET PF06985.11 EPE31160.1 - 1.7e-21 77.1 0.0 3.6e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CAMSAP_CH PF11971.8 EPE31160.1 - 0.079 12.8 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 CAMSAP CH domain HET PF06985.11 EPE31161.1 - 8.9e-29 100.7 0.0 1.6e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pyr_redox_2 PF07992.14 EPE31163.1 - 3.5e-38 131.5 1.3 4.6e-38 131.1 1.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE31163.1 - 3.8e-13 49.8 0.1 6.5e-09 36.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE31163.1 - 2.6e-08 33.5 0.1 3.9e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPE31163.1 - 0.00017 20.9 0.1 0.00027 20.2 0.1 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EPE31163.1 - 0.0017 18.0 2.7 0.83 9.2 0.1 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EPE31163.1 - 0.0019 18.2 0.1 13 5.7 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding TrkA_N PF02254.18 EPE31163.1 - 0.0051 17.1 0.1 1 9.6 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.12 EPE31163.1 - 0.012 14.7 0.4 3.7 6.5 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 EPE31163.1 - 0.016 14.1 1.3 0.033 13.0 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_7 PF13241.6 EPE31163.1 - 0.056 13.9 0.1 2.4 8.6 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EPE31163.1 - 0.062 13.5 0.2 17 5.7 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EPE31163.1 - 0.087 11.5 3.3 6.7 5.3 0.2 3.1 3 0 0 3 3 3 0 HI0933-like protein Thi4 PF01946.17 EPE31163.1 - 0.15 11.3 0.6 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Thi4 family TIM PF00121.18 EPE31164.1 - 8.2e-43 146.5 0.0 1e-42 146.2 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.18 EPE31165.1 - 9.9e-43 145.5 0.0 1.1e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF2620 PF10941.8 EPE31165.1 - 0.0068 16.5 0.1 0.0098 16.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF2620 Gly_rich_SFCGS PF14272.6 EPE31165.1 - 0.056 13.5 0.1 0.087 12.9 0.1 1.3 1 0 0 1 1 1 0 Glycine-rich SFCGS CorA PF01544.18 EPE31166.1 - 2.9e-08 33.4 2.4 2.9e-08 33.4 2.4 1.7 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Abhydrolase_1 PF00561.20 EPE31167.1 - 4.1e-23 82.3 0.0 5.3e-22 78.7 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE31167.1 - 1.9e-16 60.0 0.0 9.7e-16 57.8 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPE31167.1 - 5.5e-14 53.3 0.0 3.8e-13 50.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 EPE31167.1 - 5e-06 26.0 0.0 1.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 EPE31167.1 - 3.6e-05 23.5 0.0 6.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 EPE31167.1 - 0.0032 16.4 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 EPE31167.1 - 0.0041 16.9 0.0 7 6.4 0.0 3.2 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 EPE31167.1 - 0.014 15.5 0.4 0.12 12.5 0.4 2.2 1 1 0 1 1 1 0 Thioesterase domain Chlorophyllase PF07224.11 EPE31167.1 - 0.014 14.4 0.0 0.043 12.8 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase LIDHydrolase PF10230.9 EPE31167.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 EPE31167.1 - 0.03 14.1 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 EPE31167.1 - 0.043 13.7 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 EPE31167.1 - 0.082 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family TPR_10 PF13374.6 EPE31167.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Spo7 PF03907.13 EPE31168.1 - 6.5e-95 316.8 0.0 1e-94 316.1 0.0 1.3 1 0 0 1 1 1 1 Spo7-like protein Transketolase_N PF00456.21 EPE31169.1 - 2e-13 50.0 1.7 4.2e-12 45.7 1.7 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 EPE31169.1 - 2.2e-09 37.2 0.0 5.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 EPE31169.1 - 0.0002 21.1 0.3 0.00043 20.0 0.3 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 EPE31169.1 - 0.0013 18.5 0.1 0.0078 16.0 0.1 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PFOR_II PF17147.4 EPE31169.1 - 0.014 15.7 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II DHOR PF06537.11 EPE31170.1 - 0.11 11.0 0.0 0.14 10.7 0.0 1.0 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase GrpE PF01025.19 EPE31172.1 - 0.00038 20.2 0.8 0.00052 19.7 0.8 1.1 1 0 0 1 1 1 1 GrpE GAS PF13851.6 EPE31172.1 - 0.019 14.3 0.8 0.029 13.7 0.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 EPE31172.1 - 0.019 14.9 0.3 0.034 14.1 0.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.9 EPE31172.1 - 0.036 14.4 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 M PF02370.16 EPE31172.1 - 0.18 12.4 5.6 0.34 11.6 4.3 2.2 2 0 0 2 2 2 0 M protein repeat LysM PF01476.20 EPE31173.1 - 0.00034 20.6 0.0 0.00064 19.7 0.0 1.5 1 0 0 1 1 1 1 LysM domain SNN_cytoplasm PF09051.10 EPE31173.1 - 1 9.2 4.0 47 3.9 0.1 3.7 4 0 0 4 4 4 0 Stannin cytoplasmic FmdA_AmdA PF03069.15 EPE31174.1 - 5.4e-54 183.5 0.0 3.1e-30 105.3 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family TFCD_C PF12612.8 EPE31175.1 - 7.2e-17 61.8 3.3 1.7e-15 57.3 0.3 3.6 3 1 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 EPE31175.1 - 0.00013 22.0 6.7 0.72 10.3 0.0 6.8 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 EPE31175.1 - 0.00013 22.4 13.1 0.35 11.4 0.1 7.0 7 0 0 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.6 EPE31175.1 - 0.025 14.9 9.1 3.9 7.9 0.1 5.1 4 2 1 5 5 5 0 HEAT repeats MMS19_C PF12460.8 EPE31175.1 - 0.028 13.5 1.3 7.8 5.5 0.0 3.5 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal M11L PF11099.8 EPE31175.1 - 0.19 12.0 0.0 0.41 10.9 0.0 1.5 1 0 0 1 1 1 0 Apoptosis regulator M11L like Abhydrolase_3 PF07859.13 EPE31176.1 - 1.2e-28 100.4 0.0 1.9e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EPE31176.1 - 0.00023 20.2 0.0 0.00027 19.9 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Fungal_trans PF04082.18 EPE31177.1 - 1.6e-09 37.2 0.0 2.9e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE31177.1 - 1.3e-05 25.2 11.2 3.3e-05 23.9 11.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDIX PF00293.28 EPE31178.1 - 7.7e-10 38.9 0.0 1.2e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 EPE31178.1 - 4.2e-08 33.2 0.0 7.1e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) GST_N_2 PF13409.6 EPE31180.1 - 1.3e-16 60.7 0.0 2.5e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPE31180.1 - 2.1e-15 56.5 0.1 4e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EPE31180.1 - 1.3e-08 34.9 0.0 2.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EPE31180.1 - 0.00014 21.6 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPE31180.1 - 0.056 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Abhydrolase_1 PF00561.20 EPE31181.1 - 1.5e-14 54.3 0.0 9e-14 51.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE31181.1 - 7.7e-10 39.7 0.5 1.2e-09 39.1 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE31181.1 - 3.6e-06 26.4 0.0 6.1e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 EPE31181.1 - 0.00031 19.5 0.0 0.0011 17.7 0.0 1.8 2 0 0 2 2 2 1 Ndr family Chlorophyllase2 PF12740.7 EPE31181.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 EPE31181.1 - 0.018 14.1 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF3742 PF12553.8 EPE31182.1 - 0.0018 18.4 0.5 0.036 14.2 0.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3742) CsbD PF05532.12 EPE31182.1 - 0.12 12.3 0.3 0.18 11.7 0.3 1.3 1 0 0 1 1 1 0 CsbD-like MFS_1 PF07690.16 EPE31184.1 - 1.4e-28 99.9 62.3 1.5e-22 80.0 29.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily YobH PF13996.6 EPE31184.1 - 0.47 10.5 8.1 0.091 12.8 1.6 3.0 3 0 0 3 3 3 0 YobH-like protein Trp_halogenase PF04820.14 EPE31185.1 - 6.8e-33 114.2 0.5 2e-17 63.2 0.3 2.5 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 EPE31185.1 - 1.1e-13 51.1 0.0 2.2e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EPE31185.1 - 2.3e-05 24.5 0.1 0.00015 21.9 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EPE31185.1 - 6.1e-05 22.5 1.8 6.1e-05 22.5 1.8 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPE31185.1 - 0.00013 21.2 0.3 0.00023 20.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE31185.1 - 0.00014 21.2 0.1 0.0003 20.1 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EPE31185.1 - 0.00025 20.3 0.2 0.00078 18.6 0.2 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EPE31185.1 - 0.0014 17.4 0.1 0.0031 16.3 0.1 1.6 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EPE31185.1 - 0.013 15.1 0.3 0.026 14.1 0.3 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPE31185.1 - 0.12 11.6 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE31185.1 - 0.17 12.4 0.1 0.52 10.9 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase C2 PF00168.30 EPE31186.1 - 9.3e-23 80.5 0.1 7.7e-13 48.6 0.0 2.8 3 0 0 3 3 3 2 C2 domain Ribonuclease_T2 PF00445.18 EPE31189.1 - 1.8e-42 145.6 0.2 1.8e-42 145.6 0.2 1.5 2 0 0 2 2 2 1 Ribonuclease T2 family FHA PF00498.26 EPE31192.1 - 2.1e-05 24.8 0.1 5.6e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 FHA domain RcpC PF16976.5 EPE31192.1 - 0.026 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Flp pilus assembly protein RcpC/CpaB Yop-YscD_cpl PF16697.5 EPE31192.1 - 0.069 13.5 0.0 1.4 9.3 0.0 2.7 2 1 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain DUF756 PF05506.12 EPE31192.1 - 0.16 12.9 0.0 9 7.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF756) TMEM234 PF10639.9 EPE31194.1 - 0.012 15.6 0.0 0.072 13.1 0.0 2.1 2 0 0 2 2 2 0 Putative transmembrane family 234 Serpentine_r_xa PF03383.15 EPE31194.1 - 0.056 13.4 1.6 0.067 13.2 0.7 1.6 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa Longin_2 PF18639.1 EPE31194.1 - 0.098 12.5 0.6 0.18 11.7 0.6 1.3 1 0 0 1 1 1 0 Yeast longin domain ABC2_membrane PF01061.24 EPE31195.1 - 7.1e-91 303.3 53.9 1.3e-46 158.6 28.3 2.7 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EPE31195.1 - 4.8e-36 124.3 0.0 5.9e-17 62.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EPE31195.1 - 9.1e-30 102.4 9.9 2.4e-28 97.8 0.0 3.5 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EPE31195.1 - 1.9e-17 63.7 0.1 4.1e-17 62.6 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EPE31195.1 - 2.2e-07 31.4 0.6 0.00087 19.7 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EPE31195.1 - 2e-06 27.8 0.2 0.00089 19.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EPE31195.1 - 3e-06 26.9 0.1 0.00019 21.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.7 EPE31195.1 - 8.2e-06 25.2 42.4 0.0034 16.5 12.4 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.6 EPE31195.1 - 9.8e-06 25.8 0.1 0.071 13.3 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.6 EPE31195.1 - 5.4e-05 23.6 0.3 0.22 12.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EPE31195.1 - 0.00014 21.5 1.1 0.031 14.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EPE31195.1 - 0.00026 20.9 0.6 1.8 8.3 0.2 3.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EPE31195.1 - 0.00029 21.4 0.1 0.36 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EPE31195.1 - 0.00068 19.1 0.0 0.2 11.1 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA PF00004.29 EPE31195.1 - 0.0031 17.9 0.2 1.1 9.7 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EPE31195.1 - 0.0056 16.6 0.0 1.9 8.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EPE31195.1 - 0.0059 16.9 0.5 3.2 8.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EPE31195.1 - 0.012 15.4 0.3 2.1 8.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EPE31195.1 - 0.023 14.3 1.2 3.2 7.3 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 EPE31195.1 - 0.032 14.5 0.2 8.6 6.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EPE31195.1 - 0.06 13.1 0.1 5.6 6.7 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 EPE31195.1 - 0.087 12.7 0.0 6.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 EPE31195.1 - 0.11 12.4 0.6 11 5.8 0.3 3.0 3 0 0 3 3 3 0 NTPase Ploopntkinase3 PF18751.1 EPE31195.1 - 0.13 12.2 0.2 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 CoA_binding_3 PF13727.6 EPE31195.1 - 0.22 11.5 4.2 3.1 7.8 0.2 3.4 3 0 0 3 3 3 0 CoA-binding domain Sugar_tr PF00083.24 EPE31199.1 - 6.1e-75 252.8 19.1 7.7e-75 252.5 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE31199.1 - 4.4e-17 62.0 25.4 7.2e-16 58.0 20.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily HATPase_c PF02518.26 EPE31201.1 - 6e-25 87.9 0.0 2.3e-24 86.0 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPE31201.1 - 1.1e-23 83.5 0.6 2.3e-23 82.5 0.6 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPE31201.1 - 4.7e-15 55.4 0.1 1.2e-14 54.1 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 EPE31201.1 - 1.9e-13 50.6 0.0 6.8e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 EPE31201.1 - 1.5e-11 44.4 0.0 7e-10 39.1 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EPE31201.1 - 3.9e-11 43.0 0.0 1.2e-07 31.8 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 EPE31201.1 - 8.4e-05 22.8 0.0 0.00028 21.1 0.1 2.0 2 0 0 2 2 2 1 PAS fold PAS_7 PF12860.7 EPE31201.1 - 0.1 12.7 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 0 PAS fold Na_H_Exchanger PF00999.21 EPE31205.1 - 5.1e-27 94.6 41.6 4.9e-21 75.0 24.0 3.0 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family Pex14_N PF04695.13 EPE31205.1 - 0.016 15.9 6.2 2.3 8.8 2.4 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Shisa PF13908.6 EPE31205.1 - 0.29 11.4 0.1 0.29 11.4 0.1 2.6 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Dicty_CAR PF05462.11 EPE31205.1 - 0.94 8.6 5.9 0.66 9.1 0.8 2.2 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor Thiolase_N PF00108.23 EPE31207.1 - 3.7e-86 288.7 2.5 6e-86 288.0 2.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EPE31207.1 - 2.9e-36 123.8 0.9 2.9e-36 123.8 0.9 1.9 2 1 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EPE31207.1 - 0.00069 19.3 3.6 0.00098 18.8 1.8 2.1 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain UQ_con PF00179.26 EPE31208.1 - 2.1e-52 176.5 0.1 2.4e-52 176.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPE31208.1 - 0.00013 21.6 0.0 0.00015 21.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EPE31208.1 - 0.091 13.1 0.0 0.16 12.2 0.0 1.4 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.23 EPE31209.1 - 2.7e-114 381.6 4.5 1.7e-113 378.9 0.1 2.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EPE31209.1 - 2.3e-27 95.8 0.4 8.8e-27 93.9 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding ATG16 PF08614.11 EPE31209.1 - 0.007 16.6 20.6 0.007 16.6 20.6 4.1 3 1 0 3 3 3 1 Autophagy protein 16 (ATG16) DUF1398 PF07166.11 EPE31209.1 - 0.036 14.1 0.2 0.096 12.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) DUF1079 PF06435.11 EPE31209.1 - 0.042 14.0 0.6 0.26 11.6 0.6 2.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) Adenine_glyco PF03352.13 EPE31209.1 - 0.082 12.7 0.1 0.31 10.8 0.1 2.0 1 0 0 1 1 1 0 Methyladenine glycosylase Virulence_fact PF13769.6 EPE31209.1 - 0.37 11.0 3.8 0.36 11.1 0.6 2.7 2 0 0 2 2 2 0 Virulence factor PspB PF06667.12 EPE31209.1 - 0.41 10.7 3.8 7.9 6.6 0.0 4.0 3 0 0 3 3 3 0 Phage shock protein B XkdW PF09636.10 EPE31209.1 - 6.7 6.9 8.8 3.8 7.6 1.1 3.1 2 1 0 2 2 2 0 XkdW protein DUF1062 PF06353.12 EPE31210.1 - 0.066 14.0 0.1 0.3 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1062) HTH_Tnp_Tc5 PF03221.16 EPE31211.1 - 5e-19 68.1 1.4 0.00027 20.9 0.0 5.7 5 0 0 5 5 5 4 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.11 EPE31211.1 - 1.6e-14 53.5 1.2 3.4e-14 52.4 1.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2_4 PF13894.6 EPE31211.1 - 0.0016 19.1 14.9 0.0025 18.5 3.9 4.2 3 0 0 3 3 3 1 C2H2-type zinc finger Homeodomain PF00046.29 EPE31211.1 - 0.0018 18.0 0.0 0.0047 16.7 0.0 1.7 1 0 0 1 1 1 1 Homeodomain Zn_clus PF00172.18 EPE31211.1 - 0.079 13.1 6.8 0.6 10.3 0.9 2.5 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.8 EPE31211.1 - 0.23 11.8 2.9 0.72 10.2 2.9 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EPE31211.1 - 0.32 11.5 20.4 0.028 14.9 3.9 3.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type Transp_cyt_pur PF02133.15 EPE31212.1 - 3.5e-71 240.3 33.7 4.1e-71 240.1 33.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Bac_luciferase PF00296.20 EPE31213.1 - 2e-50 172.0 0.1 2.8e-50 171.5 0.1 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Glyco_hydro_7 PF00840.20 EPE31214.1 - 9.5e-205 680.3 12.4 1.2e-204 680.0 12.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 EPE31214.1 - 1.2e-07 31.5 11.9 1.2e-07 31.5 11.9 4.3 4 1 0 4 4 4 1 Fungal cellulose binding domain Lipid_bd PF12888.7 EPE31214.1 - 0.36 11.3 4.7 0.77 10.2 0.5 2.5 2 0 0 2 2 2 0 Lipid-binding putative hydrolase Lipase_GDSL_2 PF13472.6 EPE31216.1 - 1.6e-17 64.5 0.1 2.1e-17 64.1 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE31216.1 - 1.9e-10 41.1 0.0 2.9e-10 40.5 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 EPE31216.1 - 4.5e-05 22.8 0.0 6.2e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 OSK domain Lipase_GDSL_3 PF14606.6 EPE31216.1 - 0.014 15.5 0.0 0.024 14.8 0.0 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF563 PF04577.14 EPE31217.1 - 3.6e-26 92.6 0.1 5.5e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) NmrA PF05368.13 EPE31218.1 - 3.1e-20 72.7 0.1 3.8e-20 72.5 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE31218.1 - 1.6e-10 41.2 0.0 3e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EPE31218.1 - 2.2e-05 24.7 0.1 8.6e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EPE31218.1 - 0.015 15.8 0.0 0.039 14.4 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TIR_2 PF13676.6 EPE31218.1 - 0.036 14.7 0.0 0.084 13.5 0.0 1.6 1 0 0 1 1 1 0 TIR domain Epimerase PF01370.21 EPE31218.1 - 0.061 12.8 0.0 0.24 10.8 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EPE31218.1 - 0.076 13.1 0.1 0.42 10.8 0.0 2.3 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus DUF2785 PF10978.8 EPE31219.1 - 0.0064 16.3 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2785) BBP2_2 PF10082.9 EPE31219.1 - 0.13 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative beta-barrel porin 2 GalP_UDP_transf PF01087.22 EPE31220.1 - 2e-71 240.2 0.0 7e-70 235.2 0.0 2.3 2 1 1 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EPE31220.1 - 1.3e-58 197.4 0.0 2.7e-58 196.4 0.0 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 EPE31220.1 - 0.0076 17.0 0.0 0.028 15.1 0.0 1.9 2 0 0 2 2 2 1 HIT domain DUF4921 PF16268.5 EPE31220.1 - 0.0087 14.9 1.0 0.024 13.5 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4921) Filament PF00038.21 EPE31220.1 - 0.039 13.5 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Intermediate filament protein Erg28 PF03694.13 EPE31221.1 - 3e-40 137.0 0.9 3.9e-40 136.6 0.9 1.1 1 0 0 1 1 1 1 Erg28 like protein adh_short PF00106.25 EPE31222.1 - 1.6e-37 128.8 0.1 2.5e-37 128.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE31222.1 - 2.7e-21 76.2 0.0 3.9e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE31222.1 - 7.7e-06 25.9 0.2 2e-05 24.6 0.2 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE31222.1 - 0.00031 20.0 0.1 0.00039 19.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Nucleoporin_N PF08801.11 EPE31223.1 - 1.7e-94 317.1 0.1 2.2e-94 316.7 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EPE31223.1 - 7.6e-56 190.1 0.5 3.2e-54 184.7 0.1 2.3 1 1 1 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal DUF659 PF04937.15 EPE31223.1 - 0.066 13.1 0.0 2 8.3 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF 659) BAR_3 PF16746.5 EPE31223.1 - 0.55 9.9 2.4 2.6 7.7 0.2 2.3 2 0 0 2 2 2 0 BAR domain of APPL family Glyco_hydro_3_C PF01915.22 EPE31224.1 - 4.7e-47 160.6 0.1 7e-47 160.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE31224.1 - 3.5e-32 112.0 0.0 6.7e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE31224.1 - 2e-24 85.5 0.0 3.9e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Pro_CA PF00484.19 EPE31225.1 - 0.0013 19.1 0.1 0.002 18.4 0.1 1.4 1 1 0 1 1 1 1 Carbonic anhydrase DUF3328 PF11807.8 EPE31226.1 - 3.6e-21 76.0 5.3 1.2e-20 74.2 5.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DNAJ_related PF12339.8 EPE31226.1 - 0.077 13.2 0.0 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 DNA-J related protein DUF3328 PF11807.8 EPE31227.1 - 1.7e-21 77.0 0.1 2.1e-21 76.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) EF-hand_7 PF13499.6 EPE31227.1 - 0.15 12.5 0.0 0.3 11.6 0.0 1.5 1 1 0 1 1 1 0 EF-hand domain pair FA_desaturase PF00487.24 EPE31228.1 - 0.026 14.3 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Fatty acid desaturase PAS_3 PF08447.12 EPE31228.1 - 0.033 14.5 0.1 0.086 13.1 0.1 1.6 1 0 0 1 1 1 0 PAS fold DUF3180 PF11377.8 EPE31228.1 - 0.088 12.9 0.2 0.14 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) DUF3328 PF11807.8 EPE31229.1 - 4.5e-15 56.0 0.0 6.5e-15 55.5 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Fungal_trans_2 PF11951.8 EPE31230.1 - 2.9e-55 187.7 2.5 3.6e-55 187.4 2.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE31230.1 - 2.3e-08 34.0 8.7 2.3e-08 34.0 8.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3328 PF11807.8 EPE31231.1 - 2.1e-31 109.4 0.0 2.3e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.16 EPE31232.1 - 5e-20 71.7 18.0 1.6e-11 43.8 1.6 2.4 2 1 1 3 3 3 3 Major Facilitator Superfamily HapK PF11639.8 EPE31233.1 - 0.062 13.8 0.1 0.12 12.8 0.1 1.5 1 1 0 1 1 1 0 REDY-like protein HapK Asp PF00026.23 EPE31236.1 - 1.1e-32 113.7 0.0 5.7e-32 111.4 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPE31236.1 - 0.00018 21.8 0.1 0.00065 20.0 0.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EPE31236.1 - 0.0037 17.1 0.0 0.011 15.5 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Alk_phosphatase PF00245.20 EPE31238.1 - 1.3e-62 212.1 0.0 1.6e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Alk_phosphatase PF00245.20 EPE31239.1 - 7.9e-17 61.3 0.0 1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Alkaline phosphatase IBR PF01485.21 EPE31241.1 - 6.4e-07 29.5 36.2 0.00036 20.7 6.3 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EPE31241.1 - 0.0016 18.2 2.6 0.0016 18.2 2.6 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) tRNA-synt_1g PF09334.11 EPE31241.1 - 0.26 10.0 3.0 0.79 8.4 1.8 1.9 1 1 1 2 2 2 0 tRNA synthetases class I (M) HAUS6_N PF14661.6 EPE31242.1 - 5.1e-54 183.3 5.1 5.1e-54 183.3 5.1 2.0 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Glyco_hydro_72 PF03198.14 EPE31243.1 - 7.2e-130 432.8 5.4 9.2e-130 432.5 5.4 1.1 1 0 0 1 1 1 1 Glucanosyltransferase ECH_1 PF00378.20 EPE31243.1 - 7.9e-55 185.9 0.0 1.3e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPE31243.1 - 1.9e-31 109.8 0.4 7.9e-30 104.5 0.5 3.1 2 1 1 3 3 3 2 Enoyl-CoA hydratase/isomerase Cellulase PF00150.18 EPE31243.1 - 0.00011 21.7 0.9 0.00031 20.3 0.9 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3328 PF11807.8 EPE31245.1 - 3.2e-33 115.4 1.6 3.6e-33 115.2 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EPE31246.1 - 6e-46 157.0 0.9 9.2e-46 156.4 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EPE31247.1 - 1.1e-52 179.1 2.2 1.4e-52 178.7 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) CsbD PF05532.12 EPE31248.1 - 0.0011 18.9 24.0 21 5.1 0.0 10.5 12 0 0 12 12 12 3 CsbD-like Tox-MPTase3 PF15639.6 EPE31248.1 - 0.0014 18.5 8.4 3.3 7.6 0.4 5.9 1 1 4 5 5 5 3 Metallopeptidase toxin 3 Dmd PF17587.2 EPE31248.1 - 0.035 14.4 2.2 1.8e+02 2.6 0.1 4.9 4 1 1 5 5 5 0 Discriminator of mRNA degradation CENP-T_C PF15511.6 EPE31248.1 - 0.38 10.9 5.4 4.1 7.6 0.0 3.8 2 1 3 5 5 5 0 Centromere kinetochore component CENP-T histone fold Baculo_11_kDa PF06143.11 EPE31249.1 - 0.057 13.0 1.2 0.083 12.5 1.2 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF2207 PF09972.9 EPE31249.1 - 0.061 12.1 0.0 0.068 11.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sigma_reg_N PF13800.6 EPE31249.1 - 0.084 13.2 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF5305 PF17231.2 EPE31249.1 - 0.17 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DHO_dh PF01180.21 EPE31250.1 - 5.8e-67 226.0 0.4 6.2e-52 176.6 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EPE31250.1 - 0.00073 18.7 0.0 1 8.3 0.0 2.5 2 1 0 2 2 2 2 FMN-dependent dehydrogenase PcrB PF01884.17 EPE31250.1 - 0.033 13.7 2.4 0.73 9.2 0.0 2.8 3 0 0 3 3 3 0 PcrB family NMO PF03060.15 EPE31250.1 - 0.034 13.5 0.1 0.058 12.8 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Coatomer_WDAD PF04053.14 EPE31251.1 - 1.9e-175 584.2 0.0 6.2e-175 582.5 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EPE31251.1 - 2e-37 126.5 5.9 8.4e-06 26.4 0.1 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE31251.1 - 1.4e-07 31.7 0.4 3 8.2 0.0 5.6 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPE31251.1 - 7.4e-05 21.6 2.9 0.051 12.2 0.1 3.9 1 1 2 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EPE31251.1 - 0.027 14.5 0.0 12 6.0 0.0 3.8 2 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 EPE31251.1 - 0.052 13.8 0.0 0.26 11.5 0.0 2.1 1 1 0 1 1 1 0 C terminal of Calcineurin-like phosphoesterase Mannitol_dh_C PF08125.13 EPE31252.1 - 3.6e-42 144.6 0.1 6e-42 143.8 0.1 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EPE31252.1 - 4.3e-19 69.2 0.2 4.3e-19 69.2 0.2 2.2 3 0 0 3 3 3 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 EPE31252.1 - 0.0018 18.2 6.3 0.0052 16.7 0.1 3.3 3 1 0 4 4 4 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EPE31252.1 - 0.0049 17.1 0.6 0.38 11.0 0.1 2.8 2 1 1 3 3 3 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 EPE31252.1 - 0.022 14.4 1.6 0.063 12.9 0.4 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain VWA_3 PF13768.6 EPE31252.1 - 0.074 13.0 0.0 1.9 8.4 0.0 2.5 2 1 0 2 2 2 0 von Willebrand factor type A domain AbiEi_1 PF09407.10 EPE31252.1 - 0.11 12.8 0.6 3.3 8.0 0.0 2.8 3 0 0 3 3 3 0 AbiEi antitoxin C-terminal domain F420_oxidored PF03807.17 EPE31252.1 - 0.13 12.9 1.5 1.1 9.9 0.4 2.8 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_25 PF13649.6 EPE31252.1 - 0.17 12.6 0.4 2 9.2 0.0 2.8 4 0 0 4 4 4 0 Methyltransferase domain hNIFK_binding PF12196.8 EPE31254.1 - 0.13 11.7 0.1 0.38 10.3 0.1 1.7 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK HigB-like_toxin PF05015.13 EPE31254.1 - 0.14 12.5 1.3 1.2 9.5 0.3 2.4 2 0 0 2 2 2 0 RelE-like toxin of type II toxin-antitoxin system HigB Rhodanese PF00581.20 EPE31255.1 - 5.4e-08 33.3 0.2 7.7e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain DUF1996 PF09362.10 EPE31257.1 - 9.9e-75 251.5 3.0 1.3e-74 251.2 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) COesterase PF00135.28 EPE31258.1 - 2.1e-81 274.4 0.0 2.4e-81 274.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EPE31258.1 - 0.00012 21.7 0.2 0.00021 20.9 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EPE31258.1 - 0.00014 21.8 0.3 0.00027 20.9 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold F-box-like PF12937.7 EPE31259.1 - 1.9e-06 27.7 1.0 4.8e-06 26.4 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE31259.1 - 0.00022 21.0 1.6 0.00043 20.1 1.6 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EPE31259.1 - 0.00065 19.6 0.1 0.001 18.9 0.1 1.3 1 0 0 1 1 1 1 F-box APH PF01636.23 EPE31261.1 - 5.9e-15 55.8 0.0 7.6e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EPE31261.1 - 4.9e-05 23.0 0.1 0.0036 16.9 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 EPE31261.1 - 0.0077 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 EPE31261.1 - 0.12 11.6 0.0 2.7 7.2 0.0 2.2 3 0 0 3 3 3 0 Protein tyrosine kinase Fructosamin_kin PF03881.14 EPE31261.1 - 0.52 9.5 2.0 2.8 7.0 0.0 2.6 2 1 1 3 3 3 0 Fructosamine kinase HD_3 PF13023.6 EPE31263.1 - 1.6e-48 164.8 0.7 6.5e-48 162.8 0.0 1.9 1 1 1 2 2 2 1 HD domain HD_2 PF12917.7 EPE31263.1 - 1.1e-11 44.9 0.1 1.9e-11 44.0 0.2 1.5 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme Hamartin PF04388.12 EPE31264.1 - 7.9 5.0 9.6 10 4.7 9.6 1.1 1 0 0 1 1 1 0 Hamartin protein CENP-B_dimeris PF09026.10 EPE31265.1 - 0.012 16.0 4.6 0.022 15.2 4.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EPE31265.1 - 2.7 6.0 4.8 3.7 5.5 4.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi PWI PF01480.17 EPE31269.1 - 1.7e-12 47.4 0.1 4.7e-12 46.1 0.1 1.8 1 0 0 1 1 1 1 PWI domain Ribosomal_S21 PF01165.20 EPE31270.1 - 1.4e-12 47.1 3.9 2.5e-12 46.3 3.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 Calpain_inhib PF00748.19 EPE31270.1 - 0.061 13.8 4.5 0.11 13.0 4.5 1.4 1 0 0 1 1 1 0 Calpain inhibitor Mucin PF01456.17 EPE31270.1 - 0.87 9.6 13.5 1.3 9.0 13.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Fungal_trans PF04082.18 EPE31271.1 - 0.00037 19.6 0.0 0.00058 19.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ZZ PF00569.17 EPE31274.1 - 7.5e-10 38.5 4.5 7.5e-10 38.5 4.5 1.8 2 0 0 2 2 2 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 EPE31274.1 - 8.2e-09 35.5 0.0 2.3e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 EPE31274.1 - 7.6e-07 29.4 0.0 2.8e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 EPE31274.1 - 0.0008 19.6 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Cobl PF09469.10 EPE31274.1 - 0.092 13.0 1.2 0.15 12.3 0.1 1.9 2 0 0 2 2 2 0 Cordon-bleu ubiquitin-like domain Pkinase PF00069.25 EPE31275.1 - 1.9e-70 237.2 0.0 2.7e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE31275.1 - 5.2e-35 121.0 0.0 8.7e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EPE31275.1 - 3.9e-10 40.3 1.3 1e-09 39.0 1.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EPE31275.1 - 5.9e-06 25.5 0.1 9.1e-06 24.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EPE31275.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.5 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 EPE31275.1 - 0.12 12.0 0.1 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PGI PF00342.19 EPE31276.1 - 1.2e-234 779.4 0.2 1.4e-234 779.2 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase zf-LITAF-like PF10601.9 EPE31278.1 - 5.9e-21 74.5 3.5 8.2e-21 74.1 3.5 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.10 EPE31278.1 - 0.031 14.4 0.3 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.13 EPE31278.1 - 0.041 13.6 0.5 0.67 9.7 0.0 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit HET PF06985.11 EPE31279.1 - 3.6e-27 95.5 0.0 7.1e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FSH1 PF03959.13 EPE31280.1 - 2.4e-20 73.1 0.0 2.7e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) HET PF06985.11 EPE31281.1 - 3.3e-24 85.9 0.1 5.3e-24 85.2 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2781 PF10914.8 EPE31283.1 - 8.5e-40 136.5 10.7 9.8e-40 136.3 10.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Sugar_tr PF00083.24 EPE31285.1 - 2.2e-78 264.2 9.1 2.5e-78 264.0 9.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE31285.1 - 4.9e-32 111.2 26.9 2.4e-29 102.3 12.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPE31285.1 - 1.8e-05 23.5 5.4 0.00029 19.5 0.3 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 EPE31285.1 - 0.22 9.7 5.8 0.075 11.3 0.4 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PTR2 PF00854.21 EPE31285.1 - 3 6.6 6.9 1.6 7.4 0.6 2.3 2 0 0 2 2 2 0 POT family CorA PF01544.18 EPE31286.1 - 0.069 12.5 0.2 0.14 11.4 0.1 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Peptidase_M4_C PF02868.15 EPE31287.1 - 2e-42 144.9 0.1 3.3e-42 144.2 0.1 1.4 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.18 EPE31287.1 - 4.4e-25 88.9 0.2 8e-25 88.0 0.2 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain PLN_propep PF16485.5 EPE31287.1 - 8.4e-08 31.8 0.2 0.0018 18.0 0.0 2.4 2 0 0 2 2 2 2 Protealysin propeptide DUF1002 PF06207.11 EPE31287.1 - 0.0081 15.7 0.2 0.017 14.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1002) Asp PF00026.23 EPE31288.1 - 7.8e-30 104.4 0.0 3.4e-25 89.1 0.0 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Phage_lysozyme PF00959.19 EPE31289.1 - 1.3e-13 51.3 0.0 1.9e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Phage lysozyme DNA_binding_1 PF01035.20 EPE31290.1 - 0.0092 16.1 0.0 0.028 14.5 0.0 1.8 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Macoilin PF09726.9 EPE31290.1 - 2.8 6.4 13.1 3 6.3 13.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF936 PF06075.12 EPE31290.1 - 7.9 5.3 24.7 12 4.6 24.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SNF2_N PF00176.23 EPE31291.1 - 1.3e-70 237.9 0.0 1.9e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE31291.1 - 7.5e-14 52.0 0.0 5.8e-13 49.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPE31291.1 - 3.3e-06 27.0 0.0 6.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 EPE31291.1 - 1.8e-05 24.6 5.0 3.3e-05 23.8 5.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 EPE31291.1 - 0.0012 18.9 0.0 0.0042 17.1 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 EPE31291.1 - 0.0016 18.2 3.5 0.0043 16.9 3.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EPE31291.1 - 0.0066 16.3 1.9 0.0066 16.3 1.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PI3_PI4_kinase PF00454.27 EPE31292.1 - 8.2e-46 156.8 0.0 1.2e-45 156.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UBN_AB PF14075.6 EPE31292.1 - 0.063 13.0 0.2 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 Ubinuclein conserved middle domain TPX2_importin PF12214.8 EPE31292.1 - 0.63 10.2 3.9 0.4 10.9 0.2 2.2 2 0 0 2 2 2 0 Cell cycle regulated microtubule associated protein Methyltransf_8 PF05148.15 EPE31293.1 - 1.1e-58 198.7 0.0 8.8e-57 192.5 0.0 2.7 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EPE31293.1 - 6.8e-05 23.4 0.0 0.0005 20.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE31293.1 - 0.002 18.8 0.0 0.17 12.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPE31293.1 - 0.011 15.3 0.0 0.96 9.0 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.6 EPE31293.1 - 0.021 14.8 0.0 0.021 14.8 0.0 3.1 2 1 0 2 2 2 0 Methyltransferase domain Asp_protease PF09668.10 EPE31294.1 - 2.3e-62 208.3 0.2 3.5e-62 207.7 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EPE31294.1 - 9.5e-25 87.0 0.1 2.5e-24 85.7 0.1 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EPE31294.1 - 3.1e-12 46.9 0.3 1.9e-11 44.4 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.23 EPE31294.1 - 9.2e-12 44.6 0.0 1.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EPE31294.1 - 8.1e-09 35.2 0.1 1.9e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 EPE31294.1 - 0.00015 21.5 0.0 0.00028 20.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RVP PF00077.20 EPE31294.1 - 0.00025 21.3 0.1 0.0047 17.2 0.0 2.3 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP_2 PF08284.11 EPE31294.1 - 0.00026 20.8 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RuvA_C PF07499.13 EPE31294.1 - 0.0022 18.4 0.0 0.0069 16.8 0.0 1.8 1 0 0 1 1 1 1 RuvA, C-terminal domain UBA_4 PF14555.6 EPE31294.1 - 0.0085 15.9 0.4 0.031 14.1 0.0 2.0 2 0 0 2 2 2 1 UBA-like domain UN_NPL4 PF11543.8 EPE31294.1 - 0.017 15.6 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF2407 PF10302.9 EPE31294.1 - 0.13 12.9 0.1 0.28 11.8 0.1 1.7 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain GET2 PF08690.10 EPE31294.1 - 2.7 7.6 5.1 4.5 6.8 5.1 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Nup35_RRM_2 PF14605.6 EPE31296.1 - 3.8e-08 33.2 0.0 1.4e-05 25.0 0.1 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 EPE31296.1 - 1.9e-06 27.6 0.1 7.4e-06 25.7 0.1 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 EPE31296.1 - 1.4e-05 25.3 0.0 2.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf_CCCH_4 PF18345.1 EPE31296.1 - 0.0024 17.9 3.4 0.0042 17.1 3.4 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EPE31296.1 - 0.0063 16.4 4.8 0.011 15.6 4.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MAJIN PF15077.6 EPE31296.1 - 0.23 11.2 8.2 0.46 10.2 3.5 2.2 2 0 0 2 2 2 0 Membrane-anchored junction protein PHM7_cyt PF14703.6 EPE31296.1 - 0.25 11.6 0.1 0.25 11.6 0.1 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Seryl_tRNA_N PF02403.22 EPE31296.1 - 0.4 10.9 13.6 0.81 10.0 13.6 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 EPE31296.1 - 1.1 8.5 8.1 1.8 7.9 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EPE31296.1 - 8.5 5.2 14.0 13 4.5 14.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Xpo1 PF08389.12 EPE31297.1 - 5.4e-29 101.2 1.1 2.6e-27 95.7 0.4 3.5 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 EPE31297.1 - 3.6e-07 30.0 0.1 9.7e-07 28.6 0.1 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 EPE31297.1 - 0.0014 17.3 0.8 0.38 9.3 0.2 2.7 2 1 0 2 2 2 2 Adaptin N terminal region UME PF08064.13 EPE31297.1 - 0.0091 15.9 1.5 3.6 7.6 0.1 3.9 3 0 0 3 3 3 1 UME (NUC010) domain F-box-like PF12937.7 EPE31297.1 - 0.017 15.0 0.3 0.18 11.7 0.3 2.7 2 0 0 2 2 2 0 F-box-like DUF1722 PF08349.11 EPE31297.1 - 0.04 14.2 0.0 4.7 7.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1722) Ribosomal_S5_C PF03719.15 EPE31297.1 - 0.14 11.6 0.0 0.44 10.0 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain LSM PF01423.22 EPE31298.1 - 1.3e-15 56.8 0.1 1.6e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EPE31298.1 - 0.0039 16.8 0.1 0.0059 16.2 0.1 1.3 1 0 0 1 1 1 1 Hfq protein PhnA PF03831.14 EPE31298.1 - 0.054 13.4 0.0 0.57 10.1 0.0 2.1 2 0 0 2 2 2 0 PhnA domain 5-FTHF_cyc-lig PF01812.20 EPE31299.1 - 4.2e-32 111.5 0.0 1.2e-31 110.0 0.0 1.7 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Rot1 PF10681.9 EPE31300.1 - 1.1e-93 312.5 0.1 1.5e-93 312.2 0.1 1.1 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal His_Phos_2 PF00328.22 EPE31301.1 - 7.1e-67 226.4 0.0 8.5e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Iso_dh PF00180.20 EPE31302.1 - 5e-98 328.4 0.0 6.2e-98 328.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sec5 PF15469.6 EPE31303.1 - 7.8e-40 136.7 0.0 7e-39 133.6 0.0 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 EPE31303.1 - 2.3e-06 27.6 6.4 1.5e-05 24.9 0.1 3.7 3 1 0 3 3 3 1 Vps51/Vps67 Sec15 PF04091.12 EPE31303.1 - 0.0017 17.8 0.3 0.0032 16.9 0.3 1.3 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Rx_N PF18052.1 EPE31303.1 - 0.097 13.0 0.5 1.2 9.5 0.1 2.9 3 0 0 3 3 3 0 Rx N-terminal domain Cep57_MT_bd PF06657.13 EPE31303.1 - 3.6 8.1 5.9 17 6.0 0.2 3.3 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Trypsin_2 PF13365.6 EPE31304.1 - 2.8e-27 96.4 0.0 4.2e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EPE31304.1 - 4.1e-07 30.0 0.0 7.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin Peptidase_S32 PF05579.13 EPE31304.1 - 0.001 18.3 0.1 0.0034 16.6 0.0 1.7 2 0 0 2 2 2 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.9 EPE31304.1 - 0.16 10.6 0.3 9.4 4.7 0.0 2.1 2 0 0 2 2 2 0 Peptidase S46 Zn_clus PF00172.18 EPE31305.1 - 4.7 7.4 15.0 0.39 10.9 9.8 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain YqeY PF09424.10 EPE31306.1 - 5.1e-23 81.7 1.0 6.5e-23 81.4 1.0 1.0 1 0 0 1 1 1 1 Yqey-like protein Fungal_trans_2 PF11951.8 EPE31307.1 - 3.9e-14 52.3 3.0 1.4e-12 47.1 3.0 2.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE31307.1 - 4e-06 26.8 12.7 7.4e-06 26.0 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GGACT PF06094.12 EPE31308.1 - 1.2e-13 51.7 0.1 1.7e-13 51.2 0.1 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Abhydrolase_1 PF00561.20 EPE31309.1 - 1.5e-15 57.6 0.8 2.8e-15 56.7 0.8 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE31309.1 - 7.7e-15 56.1 0.0 1.6e-14 55.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE31309.1 - 4.8e-06 26.0 0.0 6.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EPE31309.1 - 1.3e-05 24.1 0.0 1.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.7 EPE31309.1 - 6.7e-05 21.9 0.1 0.00011 21.2 0.1 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EPE31309.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Ribosomal_L18_c PF14204.6 EPE31309.1 - 0.042 14.8 0.0 0.11 13.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region ADH_N PF08240.12 EPE31310.1 - 6.8e-08 32.4 0.5 1.2e-07 31.5 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE31310.1 - 3e-07 30.5 0.1 5.8e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE31310.1 - 0.0022 19.1 0.0 0.0044 18.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EPE31310.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase MTHFR PF02219.17 EPE31311.1 - 1.6e-115 385.3 0.0 3.1e-115 384.4 0.0 1.4 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase GCP_N_terminal PF17681.1 EPE31312.1 - 3e-63 214.3 0.1 8.3e-63 212.8 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EPE31312.1 - 1.4e-61 208.6 4.7 1.4e-61 208.6 4.7 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal PspA_IM30 PF04012.12 EPE31312.1 - 0.31 10.6 1.6 8.4 5.9 0.2 2.3 2 0 0 2 2 2 0 PspA/IM30 family Tropomyosin_1 PF12718.7 EPE31312.1 - 3.5 7.8 7.1 0.74 10.0 0.2 2.7 2 1 1 3 3 3 0 Tropomyosin like Proteasome PF00227.26 EPE31313.1 - 6.9e-56 188.8 0.1 8.7e-56 188.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EPE31313.1 - 1.8e-12 46.7 0.0 3.6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pro_CA PF00484.19 EPE31314.1 - 6.8e-06 26.5 0.0 9.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase Ank_2 PF12796.7 EPE31315.1 - 1.1e-21 77.3 5.2 5.4e-07 30.1 0.1 6.6 5 1 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE31315.1 - 1.1e-20 73.7 8.3 1.8e-07 31.6 0.1 8.3 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Pkinase PF00069.25 EPE31315.1 - 1.1e-19 70.9 0.0 1.9e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE31315.1 - 1.8e-18 66.8 0.0 5e-18 65.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_3 PF13606.6 EPE31315.1 - 1.3e-16 59.0 4.1 0.00021 21.5 0.0 9.5 10 0 0 10 10 10 2 Ankyrin repeat Ank PF00023.30 EPE31315.1 - 4.1e-11 42.8 13.7 0.0021 18.4 0.0 7.4 8 1 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 EPE31315.1 - 5.3e-11 42.6 8.7 0.0062 16.8 0.1 7.1 5 3 2 7 7 7 3 Ankyrin repeats (many copies) RVP PF00077.20 EPE31315.1 - 0.2 12.0 0.1 27 5.2 0.2 3.4 3 0 0 3 3 3 0 Retroviral aspartyl protease PIN_8 PF18476.1 EPE31316.1 - 0.047 13.5 0.3 0.078 12.8 0.3 1.2 1 0 0 1 1 1 0 PIN like domain Pkinase PF00069.25 EPE31318.1 - 0.0012 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE31318.1 - 0.028 13.7 0.0 0.089 12.1 0.0 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase Peptidase_C14 PF00656.22 EPE31318.1 - 0.075 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Caspase domain DUF1965 PF09248.10 EPE31318.1 - 0.19 11.5 0.1 0.48 10.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) GMC_oxred_N PF00732.19 EPE31319.1 - 1.4e-52 179.0 0.0 1.7e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE31319.1 - 1.9e-27 96.6 0.0 3.2e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EPE31319.1 - 8.1e-06 25.2 0.1 0.002 17.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EPE31319.1 - 0.00015 21.1 0.1 0.00024 20.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EPE31319.1 - 0.00028 20.0 0.2 0.00044 19.4 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EPE31319.1 - 0.001 18.4 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EPE31319.1 - 0.0033 16.6 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EPE31319.1 - 0.036 13.3 0.1 0.73 9.0 0.1 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE31319.1 - 0.057 13.0 0.3 2 7.9 0.5 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EPE31319.1 - 0.17 12.5 0.0 0.5 11.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ASCH PF04266.14 EPE31321.1 - 0.0062 17.1 0.0 0.0081 16.7 0.0 1.3 1 0 0 1 1 1 1 ASCH domain adh_short_C2 PF13561.6 EPE31322.1 - 2.4e-28 99.3 0.2 3.2e-28 98.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE31322.1 - 3.4e-23 82.1 0.4 4.2e-23 81.8 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE31322.1 - 0.0012 18.8 0.2 0.0018 18.2 0.2 1.3 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 EPE31322.1 - 0.0021 18.3 0.1 0.0047 17.2 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 EPE31322.1 - 0.0023 18.3 0.2 0.01 16.3 0.1 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 EPE31322.1 - 0.0029 17.5 0.1 0.0048 16.8 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EPE31322.1 - 0.13 11.5 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ORC4_C PF14629.6 EPE31323.1 - 1.4e-58 197.8 0.0 2.8e-58 196.9 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus PHD PF00628.29 EPE31323.1 - 1.3e-10 41.0 6.8 2.2e-10 40.2 6.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EPE31323.1 - 3.9e-10 39.1 2.5 8.4e-10 38.0 2.5 1.6 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 EPE31323.1 - 3e-05 23.8 0.7 3e-05 23.8 0.7 1.6 2 0 0 2 2 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_16 PF13191.6 EPE31323.1 - 0.00091 19.7 1.2 0.0026 18.2 1.2 1.8 1 0 0 1 1 1 1 AAA ATPase domain FYVE_2 PF02318.16 EPE31323.1 - 0.0082 16.4 3.0 0.011 15.9 1.5 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger Prok-RING_1 PF14446.6 EPE31323.1 - 0.032 14.1 1.6 0.07 13.1 1.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 AAA PF00004.29 EPE31323.1 - 0.045 14.2 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) C1_2 PF03107.16 EPE31323.1 - 0.053 13.8 1.6 0.14 12.5 1.6 1.7 1 0 0 1 1 1 0 C1 domain NACHT PF05729.12 EPE31323.1 - 0.12 12.3 0.1 0.33 10.9 0.1 1.7 1 0 0 1 1 1 0 NACHT domain zf-PHD-like PF15446.6 EPE31323.1 - 0.51 9.9 3.2 1.3 8.6 3.2 1.7 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain ABM PF03992.16 EPE31327.1 - 7.4e-05 22.8 2.1 0.0031 17.6 0.1 2.6 3 0 0 3 3 3 2 Antibiotic biosynthesis monooxygenase AMP-binding PF00501.28 EPE31328.1 - 8.2e-90 301.4 0.0 1.3e-89 300.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE31328.1 - 0.0034 18.3 0.1 0.0079 17.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CdhD PF03599.16 EPE31328.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Methyltransf_16 PF10294.9 EPE31329.1 - 1.8e-16 60.4 0.9 1.9e-14 53.8 0.9 2.1 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EPE31329.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 EPE31329.1 - 0.23 12.2 0.6 3.9 8.3 0.6 2.3 1 1 0 1 1 1 0 Methyltransferase domain adh_short PF00106.25 EPE31330.1 - 2.5e-86 288.1 10.5 3.1e-45 154.0 1.3 2.8 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE31330.1 - 2.7e-66 223.5 7.6 3.5e-35 121.6 1.3 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EPE31330.1 - 1.5e-28 98.9 0.0 3.2e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EPE31330.1 - 8e-28 97.6 5.0 5.1e-14 52.6 0.2 2.3 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 EPE31330.1 - 0.0009 18.6 0.7 0.0079 15.5 0.2 2.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAM25 PF15825.5 EPE31330.1 - 0.014 15.8 6.0 0.18 12.2 0.6 2.6 2 0 0 2 2 2 0 FAM25 family MaoC_dehydrat_N PF13452.6 EPE31330.1 - 0.017 15.2 0.0 9.5 6.4 0.0 2.5 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase Zeta_toxin PF06414.12 EPE31331.1 - 0.00011 21.5 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin PRK PF00485.18 EPE31331.1 - 0.00022 21.0 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EPE31331.1 - 0.00051 20.6 0.1 0.0011 19.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain MeaB PF03308.16 EPE31331.1 - 0.00055 19.0 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 EPE31331.1 - 0.00071 19.2 0.0 0.00096 18.8 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KAP_NTPase PF07693.14 EPE31331.1 - 0.00089 18.6 0.0 0.0009 18.6 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain APS_kinase PF01583.20 EPE31331.1 - 0.0046 16.9 0.0 0.0068 16.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.6 EPE31331.1 - 0.0056 17.1 0.1 0.017 15.5 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.19 EPE31331.1 - 0.0074 15.9 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SCA7 PF08313.12 EPE31331.1 - 0.01 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 SCA7, zinc-binding domain DLIC PF05783.11 EPE31331.1 - 0.019 13.8 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_30 PF13604.6 EPE31331.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EPE31331.1 - 0.022 15.3 0.0 0.042 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.17 EPE31331.1 - 0.022 14.4 0.1 0.045 13.4 0.1 1.5 1 0 0 1 1 1 0 Thymidylate kinase NACHT PF05729.12 EPE31331.1 - 0.04 13.9 0.1 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 EPE31331.1 - 0.042 13.9 0.3 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EPE31331.1 - 0.077 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PUB_1 PF18486.1 EPE31331.1 - 0.083 12.8 0.0 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain CPT PF07931.12 EPE31331.1 - 0.087 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF4373 PF14297.6 EPE31331.1 - 0.12 13.1 0.0 0.3 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4373) AAA_14 PF13173.6 EPE31331.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EPE31331.1 - 0.16 11.8 0.2 0.3 11.0 0.2 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 EPE31331.1 - 0.18 10.9 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ATP_bind_1 PF03029.17 EPE31331.1 - 0.19 11.5 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ECM11 PF15463.6 EPE31332.1 - 8.7e-23 81.4 8.8 8.7e-23 81.4 8.8 2.4 2 1 0 2 2 2 1 Extracellular mutant protein 11 Sigma70_ner PF04546.13 EPE31332.1 - 0.95 9.3 13.8 0.52 10.2 6.2 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region Glutaredoxin2_C PF04399.13 EPE31332.1 - 1.1 9.0 4.3 0.74 9.7 1.9 1.9 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain EMC3_TMCO1 PF01956.16 EPE31332.1 - 4.8 6.9 7.1 8.9 6.0 7.1 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like GTP_EFTU PF00009.27 EPE31333.1 - 6.2e-67 224.9 0.2 8.9e-67 224.4 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EPE31333.1 - 8.9e-33 112.6 0.0 3.6e-32 110.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EPE31333.1 - 6.7e-22 77.3 0.0 1.8e-21 75.9 0.0 1.7 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EPE31333.1 - 2.9e-12 46.8 0.0 1.1e-11 44.9 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EPE31333.1 - 3.6e-11 43.0 0.1 3e-10 40.1 0.0 2.4 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EPE31333.1 - 0.00073 19.6 0.2 0.0015 18.6 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Solute_trans_a PF03619.16 EPE31335.1 - 6.1e-92 307.9 2.0 7.3e-92 307.6 2.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Methyltransf_23 PF13489.6 EPE31336.1 - 1.2e-09 38.2 0.1 1.9e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE31336.1 - 6.6e-09 36.4 0.4 2.8e-07 31.2 0.3 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE31336.1 - 7.6e-07 29.7 0.1 2.7e-06 27.9 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE31336.1 - 0.0015 18.3 0.0 0.016 15.0 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE31336.1 - 0.062 14.0 0.0 0.17 12.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Lon_C PF05362.13 EPE31337.1 - 3.4e-62 209.6 0.0 9.1e-62 208.2 0.0 1.8 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EPE31337.1 - 2.7e-34 118.9 0.0 8.4e-34 117.3 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EPE31337.1 - 2.4e-22 79.8 0.0 5.6e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPE31337.1 - 1.5e-05 25.3 0.0 0.0005 20.4 0.0 2.8 1 1 0 1 1 1 1 AAA domain ChlI PF13541.6 EPE31337.1 - 1.5e-05 24.8 0.0 4.2e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 EPE31337.1 - 1.5e-05 25.0 0.0 3.5e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EPE31337.1 - 8.5e-05 22.7 1.8 9.6e-05 22.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EPE31337.1 - 0.00012 21.9 0.0 0.00066 19.5 0.0 2.3 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 EPE31337.1 - 0.00013 21.0 0.0 0.00024 20.1 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 EPE31337.1 - 0.00018 21.9 0.1 0.0019 18.6 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EPE31337.1 - 0.0081 15.9 0.0 0.032 14.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 EPE31337.1 - 0.011 15.5 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DNTTIP1_dimer PF18192.1 EPE31337.1 - 0.015 15.7 1.1 0.33 11.3 0.2 3.1 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain AAA_14 PF13173.6 EPE31337.1 - 0.022 14.8 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain CHASE8 PF17152.4 EPE31337.1 - 0.041 14.1 0.1 0.24 11.6 0.1 2.2 2 0 0 2 2 2 0 Periplasmic sensor domain RsgA_GTPase PF03193.16 EPE31337.1 - 0.052 13.4 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 EPE31337.1 - 0.052 13.4 0.1 1.9 8.4 0.0 2.7 2 1 1 3 3 2 0 NTPase RNA_helicase PF00910.22 EPE31337.1 - 0.077 13.4 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EPE31337.1 - 0.082 13.5 0.0 0.082 13.5 0.0 3.1 4 0 0 4 4 2 0 AAA domain AAA_7 PF12775.7 EPE31337.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region SKI PF01202.22 EPE31337.1 - 0.31 11.1 3.2 0.5 10.5 0.0 2.8 3 0 0 3 3 3 0 Shikimate kinase ABC_tran PF00005.27 EPE31337.1 - 0.42 11.1 3.8 0.87 10.1 0.0 2.8 3 0 0 3 3 2 0 ABC transporter Pkinase PF00069.25 EPE31339.1 - 2.2e-12 46.9 0.0 4.5e-11 42.6 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE31339.1 - 3.4e-09 36.4 0.0 7e-08 32.1 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_10 PF13673.7 EPE31340.1 - 2.8e-08 33.7 0.0 4.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE31340.1 - 7.8e-08 32.6 0.0 1.6e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE31340.1 - 3.3e-07 30.6 0.0 5.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE31340.1 - 0.0025 17.8 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EPE31340.1 - 0.024 14.8 0.1 0.072 13.2 0.1 1.8 1 1 1 2 2 2 0 GCN5-related N-acetyl-transferase NOG1_N PF17835.1 EPE31341.1 - 9.6e-49 165.4 0.1 9.6e-49 165.4 0.1 2.1 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EPE31341.1 - 1.6e-29 101.7 1.9 4.3e-29 100.3 1.9 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 EPE31341.1 - 4.2e-26 90.5 0.6 8.9e-26 89.4 0.6 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EPE31341.1 - 1.6e-15 57.2 0.0 3.4e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPE31341.1 - 1.5e-08 34.3 0.0 2.9e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EPE31341.1 - 0.00081 19.8 0.1 0.045 14.1 0.1 3.3 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EPE31341.1 - 0.0018 18.2 0.2 0.85 9.5 0.0 3.3 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 EPE31341.1 - 0.0051 16.9 0.1 3.4 7.7 0.0 2.8 1 1 0 2 2 2 2 Dynamin family Roc PF08477.13 EPE31341.1 - 0.085 13.1 0.0 0.51 10.6 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pribosyltran PF00156.27 EPE31342.1 - 3.7e-12 46.0 0.2 5.2e-12 45.6 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain BRO1 PF03097.18 EPE31343.1 - 2.4e-129 431.6 0.9 2.4e-129 431.6 0.9 2.2 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EPE31343.1 - 6.3e-80 268.6 20.6 1.3e-79 267.6 20.6 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF1640 PF07798.11 EPE31343.1 - 0.046 13.8 16.9 0.48 10.5 10.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Gp58 PF07902.11 EPE31343.1 - 0.079 11.2 9.4 0.14 10.4 9.4 1.3 1 0 0 1 1 1 0 gp58-like protein Phage_tail_APC PF16778.5 EPE31343.1 - 0.083 12.8 1.2 0.33 10.8 0.4 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone protein DUF3232 PF11554.8 EPE31343.1 - 0.14 12.6 4.5 0.089 13.2 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3232) FlaC_arch PF05377.11 EPE31343.1 - 0.15 12.4 2.4 0.48 10.9 0.0 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DnaJ_C PF01556.18 EPE31344.1 - 1.1e-38 132.6 0.2 1.6e-38 132.1 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EPE31344.1 - 1.4e-20 73.2 1.3 3.7e-20 71.8 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EPE31344.1 - 3e-08 33.9 22.2 6.8e-08 32.8 22.2 1.7 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.6 EPE31344.1 - 0.3 11.1 8.9 1.8 8.7 0.3 3.0 3 0 0 3 3 3 0 Cytochrome c7 and related cytochrome c A2L_zn_ribbon PF08792.10 EPE31344.1 - 0.93 9.3 11.1 17 5.2 0.9 3.5 2 1 1 3 3 3 0 A2L zinc ribbon domain HypA PF01155.19 EPE31344.1 - 9.9 6.2 10.2 3.1 7.9 1.4 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SAP30_Sin3_bdg PF13867.6 EPE31345.1 - 2.7e-07 30.8 1.7 4.9e-07 30.0 0.0 2.2 3 0 0 3 3 3 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Fungal_trans PF04082.18 EPE31347.1 - 1.4e-70 237.4 0.3 2e-70 236.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPE31347.1 - 1.7e-05 25.0 9.8 0.00033 20.9 0.8 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPE31347.1 - 5.7 7.5 10.4 2.2 8.9 0.9 3.2 3 0 0 3 3 3 0 Zinc-finger double domain PA26 PF04636.13 EPE31348.1 - 0.71 8.7 7.0 0.94 8.3 7.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SesA PF17107.5 EPE31349.1 - 8e-05 22.8 0.1 0.00099 19.3 0.0 2.4 1 1 1 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases MCPsignal PF00015.21 EPE31349.1 - 0.0014 18.4 1.7 0.0025 17.6 1.7 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain UPF0242 PF06785.11 EPE31349.1 - 0.018 15.1 4.7 0.032 14.3 4.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ArAE_1_C PF11728.8 EPE31349.1 - 0.037 14.0 5.0 0.074 13.0 5.0 1.4 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain DUF668 PF05003.12 EPE31349.1 - 0.048 14.1 1.0 0.2 12.1 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF668) zf-C4pol PF14260.6 EPE31349.1 - 0.095 13.2 0.7 0.28 11.7 0.7 1.8 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta DUF1664 PF07889.12 EPE31349.1 - 0.1 12.6 4.6 0.22 11.6 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-ribbon_3 PF13248.6 EPE31349.1 - 0.27 10.7 2.0 0.64 9.5 1.9 1.7 1 1 0 1 1 1 0 zinc-ribbon domain DUF745 PF05335.13 EPE31349.1 - 0.3 10.8 4.1 0.47 10.2 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) zf-tcix PF14952.6 EPE31349.1 - 0.35 10.5 1.8 0.75 9.5 1.8 1.6 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding zf-MYND PF01753.18 EPE31351.1 - 0.0015 18.6 14.0 0.0029 17.6 14.0 1.5 1 0 0 1 1 1 1 MYND finger CstA PF02554.14 EPE31352.1 - 0.029 13.3 1.8 0.04 12.8 1.8 1.1 1 0 0 1 1 1 0 Carbon starvation protein CstA DUF5110 PF17137.4 EPE31352.1 - 0.16 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) NACHT PF05729.12 EPE31353.1 - 2.6e-08 34.0 0.0 7.5e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EPE31353.1 - 0.0027 18.1 0.1 0.011 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.7 EPE31353.1 - 0.12 13.0 0.0 0.21 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PD40 PF07676.12 EPE31354.1 - 0.11 12.4 1.1 0.18 11.8 1.1 1.3 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Glyco_hydro_61 PF03443.14 EPE31355.1 - 4e-57 193.5 0.2 6.6e-57 192.8 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EPE31355.1 - 2.9e-12 46.3 8.9 9.4e-12 44.7 8.9 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF218 PF02698.17 EPE31356.1 - 9.5e-06 25.7 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain Methyltransf_23 PF13489.6 EPE31357.1 - 1.7e-12 47.5 0.0 2.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE31357.1 - 4.5e-06 27.2 0.0 1.5e-05 25.6 0.0 1.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE31357.1 - 5.7e-05 23.8 0.0 0.00018 22.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE31357.1 - 0.00024 21.8 0.0 0.00075 20.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE31357.1 - 0.00034 20.4 0.0 0.0013 18.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EPE31358.1 - 2.5e-18 66.1 0.0 4.9e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_8 PF05148.15 EPE31358.1 - 0.053 13.4 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Glyco_hydro_12 PF01670.16 EPE31359.1 - 6.7e-39 134.1 11.5 7.7e-39 133.9 11.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Sugar_tr PF00083.24 EPE31360.1 - 5.8e-83 279.3 22.0 7e-83 279.0 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE31360.1 - 3.7e-30 105.0 28.8 2.7e-29 102.2 23.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPE31360.1 - 3.6e-06 25.8 19.8 5.2e-06 25.3 4.6 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein DUF3292 PF11696.8 EPE31361.1 - 3.1e-285 947.7 0.0 3.6e-285 947.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Pex24p PF06398.11 EPE31361.1 - 0.033 13.2 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin RecA PF00154.21 EPE31362.1 - 5.6e-08 32.6 0.2 9.6e-08 31.8 0.2 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 EPE31362.1 - 5.1e-06 25.9 0.0 2.1e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 EPE31362.1 - 3.2e-05 23.4 0.0 5.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 EPE31362.1 - 0.0036 16.9 0.4 0.021 14.4 0.4 2.2 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EPE31362.1 - 0.0059 15.8 0.0 0.0093 15.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 EPE31362.1 - 0.0078 16.6 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EPE31362.1 - 0.04 13.8 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EPE31362.1 - 0.06 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 EPE31362.1 - 0.074 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EPE31362.1 - 0.092 13.0 0.0 0.22 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Ribonuclease_T2 PF00445.18 EPE31363.1 - 4.1e-37 128.2 0.0 6.2e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Hap4_Hap_bind PF10297.9 EPE31364.1 - 7.2e-06 26.0 9.4 7.2e-06 26.0 9.4 1.8 2 0 0 2 2 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 EPE31364.1 - 1.2e-05 25.3 12.7 0.00013 22.0 11.8 2.4 1 1 1 2 2 2 1 bZIP transcription factor MAD PF05557.13 EPE31364.1 - 0.0031 15.9 4.4 0.0057 15.1 4.4 1.4 1 0 0 1 1 1 1 Mitotic checkpoint protein IFT20 PF14931.6 EPE31364.1 - 0.018 15.2 4.0 0.032 14.4 4.0 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 HIP1_clath_bdg PF16515.5 EPE31364.1 - 0.026 15.1 5.1 0.055 14.1 5.1 1.6 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fmp27_WPPW PF10359.9 EPE31364.1 - 0.048 12.5 1.6 0.077 11.8 1.6 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TolA_bind_tri PF16331.5 EPE31364.1 - 0.053 13.6 2.8 0.11 12.5 2.8 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation SHE3 PF17078.5 EPE31364.1 - 0.069 12.9 0.4 0.11 12.2 0.4 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 dsrm PF00035.26 EPE31364.1 - 0.1 13.3 0.0 0.34 11.7 0.0 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding motif ACCA PF03255.14 EPE31364.1 - 0.14 12.0 1.8 0.27 11.1 1.8 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Golgin_A5 PF09787.9 EPE31364.1 - 0.17 11.3 7.2 0.28 10.6 7.2 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Striatin PF08232.12 EPE31364.1 - 0.23 12.1 7.8 0.3 11.7 6.2 2.1 1 1 0 1 1 1 0 Striatin family I_LWEQ PF01608.17 EPE31364.1 - 0.89 9.8 5.5 1.7 8.8 5.5 1.4 1 0 0 1 1 1 0 I/LWEQ domain DUF4200 PF13863.6 EPE31364.1 - 2.4 8.6 11.7 4.9 7.6 11.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) COG2 PF06148.11 EPE31365.1 - 6.4e-29 100.7 0.0 9.3e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EPE31365.1 - 0.00016 21.7 0.1 0.00039 20.4 0.1 1.7 1 0 0 1 1 1 1 Vps51/Vps67 Importin_rep_4 PF18808.1 EPE31365.1 - 0.1 12.9 1.9 0.26 11.6 1.9 1.7 1 0 0 1 1 1 0 Importin repeat Spc7 PF08317.11 EPE31365.1 - 0.12 11.2 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Uso1_p115_C PF04871.13 EPE31365.1 - 9.9 6.6 11.3 28 5.1 7.6 2.6 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Ribosomal_L1 PF00687.21 EPE31366.1 - 1.1e-28 100.4 0.1 1.9e-28 99.6 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.21 EPE31367.1 - 8.6e-104 346.8 0.0 1.2e-103 346.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EPE31367.1 - 4.5e-39 134.1 0.2 7.3e-39 133.4 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 EPE31367.1 - 0.01 15.2 0.9 0.028 13.8 0.4 1.7 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain Ribosomal_L27 PF01016.19 EPE31368.1 - 1.3e-30 105.2 0.2 2.3e-30 104.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein DUF935 PF06074.12 EPE31371.1 - 0.069 11.9 2.4 0.11 11.3 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Kelch_5 PF13854.6 EPE31372.1 - 1.2e-09 37.9 0.4 1.2e-09 37.9 0.4 3.7 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 EPE31372.1 - 1.2e-05 24.7 7.7 0.031 13.8 0.8 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EPE31372.1 - 0.00021 21.5 0.5 0.00021 21.5 0.5 3.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Phage_holin_2_1 PF04971.12 EPE31372.1 - 0.38 10.8 2.2 2 8.4 0.1 2.6 2 0 0 2 2 2 0 Bacteriophage P21 holin S Kelch_2 PF07646.15 EPE31372.1 - 0.38 10.8 6.9 3.5 7.8 0.6 4.2 4 1 0 4 4 4 0 Kelch motif Kelch_6 PF13964.6 EPE31372.1 - 0.62 10.4 6.1 0.21 11.9 0.5 3.2 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.6 EPE31372.1 - 1.5 8.9 13.5 0.06 13.4 0.7 4.7 5 2 0 5 5 5 0 Galactose oxidase, central domain PetG PF02529.15 EPE31372.1 - 1.7 8.6 5.5 0.29 11.0 0.7 2.1 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 DAN PF03045.15 EPE31373.1 - 0.026 14.6 0.6 0.072 13.1 0.6 1.7 1 0 0 1 1 1 0 DAN domain Piwi PF02171.17 EPE31374.1 - 1e-52 179.3 0.0 1.6e-52 178.7 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EPE31374.1 - 4.3e-12 46.8 0.0 7.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EPE31374.1 - 1.8e-07 30.7 0.9 3.7e-07 29.7 0.9 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain Ank_2 PF12796.7 EPE31375.1 - 3.2e-24 85.3 0.6 1.7e-06 28.5 0.1 4.6 2 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE31375.1 - 4.7e-19 68.5 0.8 2.1e-08 34.5 0.0 5.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE31375.1 - 2.9e-16 59.3 1.1 4.9e-06 26.7 0.0 5.3 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE31375.1 - 7.5e-15 53.6 1.9 0.013 16.0 0.0 8.2 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 EPE31375.1 - 2.1e-09 37.4 11.1 0.1 13.1 0.0 6.7 8 0 0 8 8 8 3 Ankyrin repeat NACHT PF05729.12 EPE31375.1 - 0.027 14.4 0.1 0.098 12.6 0.1 1.9 1 0 0 1 1 1 0 NACHT domain TetR_C_29 PF17938.1 EPE31375.1 - 0.07 13.2 0.2 3.4 7.8 0.0 3.1 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Flavi_NS4B PF01349.17 EPE31375.1 - 0.089 12.2 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4B Viral_helicase1 PF01443.18 EPE31376.1 - 0.026 14.3 0.1 0.081 12.7 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 EPE31376.1 - 0.11 13.0 0.6 0.4 11.1 0.1 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPE31376.1 - 0.13 12.5 0.1 0.65 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EPE31376.1 - 0.13 12.6 0.2 1.7 9.0 0.0 2.3 2 1 0 2 2 2 0 RNA helicase 2OG-FeII_Oxy PF03171.20 EPE31377.1 - 1.3e-17 64.2 0.0 2.3e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EPE31377.1 - 4.5e-10 40.3 0.0 6.7e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Methyltransf_2 PF00891.18 EPE31380.1 - 1.9e-19 69.8 0.0 3.1e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain HTH_Crp_2 PF13545.6 EPE31380.1 - 0.16 12.0 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Dimerisation PF08100.11 EPE31380.1 - 1.4 9.0 3.6 1.5 8.9 0.4 2.5 2 0 0 2 2 2 0 Dimerisation domain LPMO_10 PF03067.15 EPE31382.1 - 9e-11 42.8 0.6 1.2e-10 42.4 0.6 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading ArAE_2_N PF10337.9 EPE31383.1 - 2.4e-18 66.5 16.9 3.3e-10 39.6 0.2 3.4 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EPE31383.1 - 9.7e-13 48.4 18.0 9.7e-13 48.4 18.0 3.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.8 EPE31383.1 - 3.2e-07 29.6 7.8 3.2e-07 29.6 7.8 3.6 4 0 0 4 4 4 2 Aluminium activated malate transporter ArAE_2 PF10334.9 EPE31383.1 - 1.6e-05 24.9 0.1 3.3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 VIT1 PF01988.19 EPE31383.1 - 0.053 13.4 4.2 15 5.4 0.0 3.4 2 0 0 2 2 2 0 VIT family MFMR_assoc PF16596.5 EPE31383.1 - 3.1 8.3 7.4 43 4.6 7.5 2.7 2 0 0 2 2 2 0 Disordered region downstream of MFMR Glyco_transf_15 PF01793.16 EPE31384.1 - 1.8e-97 326.5 4.1 4.4e-97 325.2 4.1 1.5 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF512 PF04459.12 EPE31384.1 - 0.034 13.4 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Ist1 PF03398.14 EPE31385.1 - 2.8e-61 206.2 3.5 3.7e-61 205.8 3.5 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Acyl-CoA_dh_1 PF00441.24 EPE31386.1 - 4.1e-29 101.7 1.8 6.2e-29 101.2 1.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EPE31386.1 - 1.2e-19 70.2 0.0 2.2e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EPE31386.1 - 1.3e-19 70.9 0.0 2.7e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EPE31386.1 - 3.2e-15 56.6 1.0 7.9e-15 55.3 0.4 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain INCENP_ARK-bind PF03941.15 EPE31387.1 - 3.2e-15 55.8 4.0 3.2e-15 55.8 4.0 3.2 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region Pyrid_ox_like PF16242.5 EPE31388.1 - 2.1e-23 82.5 0.0 3.3e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EPE31388.1 - 1.9e-07 31.2 0.0 3.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1449 PF07290.11 EPE31388.1 - 0.17 11.5 0.2 0.25 11.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) DivIC PF04977.15 EPE31389.1 - 0.14 11.9 1.4 0.65 9.8 0.8 2.0 2 0 0 2 2 2 0 Septum formation initiator DUF3409 PF11889.8 EPE31390.1 - 0.025 14.5 0.0 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3409) DUF908 PF06012.12 EPE31390.1 - 0.29 10.5 3.7 0.36 10.2 3.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MSA-2c PF12238.8 EPE31390.1 - 9 6.2 11.0 14 5.6 11.0 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF5340 PF17275.2 EPE31391.1 - 1.6 8.9 5.6 3.5 7.8 0.3 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5340) TolA_bind_tri PF16331.5 EPE31392.1 - 0.023 14.8 1.6 0.04 14.0 1.6 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF4618 PF15397.6 EPE31392.1 - 0.027 13.9 0.1 0.035 13.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) PV-1 PF06637.11 EPE31392.1 - 0.029 13.2 0.1 0.035 12.9 0.1 1.0 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DASH_Spc19 PF08287.11 EPE31392.1 - 0.069 13.0 0.4 0.093 12.6 0.4 1.3 1 1 0 1 1 1 0 Spc19 CASP_C PF08172.12 EPE31392.1 - 0.096 12.0 0.7 0.12 11.6 0.7 1.2 1 0 0 1 1 1 0 CASP C terminal DivIC PF04977.15 EPE31392.1 - 0.1 12.4 0.3 0.15 11.8 0.3 1.2 1 0 0 1 1 1 0 Septum formation initiator adh_short PF00106.25 EPE31394.1 - 5.1e-19 68.5 0.0 7e-17 61.5 0.0 2.6 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE31394.1 - 1e-13 51.4 0.0 8e-12 45.2 0.0 2.8 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EPE31394.1 - 0.00038 20.4 0.0 0.00064 19.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE31394.1 - 0.00075 19.0 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EPE31394.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 EPE31394.1 - 0.022 14.3 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 EPE31394.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Exo5 PF09810.9 EPE31395.1 - 8.1e-142 473.1 0.0 9.8e-142 472.8 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 EPE31395.1 - 0.00054 20.0 0.1 1.5 8.6 0.3 2.8 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily PAS_9 PF13426.7 EPE31397.1 - 2.1e-16 60.1 0.0 4.9e-15 55.7 0.0 2.8 2 1 0 2 2 2 1 PAS domain RGS PF00615.19 EPE31397.1 - 5e-13 49.4 0.0 1.1e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS PF00989.25 EPE31397.1 - 0.00024 21.1 0.0 0.006 16.6 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EPE31397.1 - 0.0018 18.5 0.0 2.6 8.3 0.0 3.3 4 0 0 4 4 4 2 PAS fold PAS_3 PF08447.12 EPE31397.1 - 0.04 14.2 0.0 0.29 11.4 0.0 2.4 2 1 0 2 2 2 0 PAS fold Bromodomain PF00439.25 EPE31399.1 - 1.4e-18 66.7 0.2 3.1e-18 65.6 0.2 1.6 1 0 0 1 1 1 1 Bromodomain BTB PF00651.31 EPE31399.1 - 0.0016 18.6 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF2780 PF11075.8 EPE31399.1 - 0.19 11.8 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) CBM_1 PF00734.18 EPE31401.1 - 2.8e-05 24.0 15.8 0.00014 21.7 15.8 2.1 1 1 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL_lke PF16255.5 EPE31401.1 - 0.12 11.6 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Abhydrolase_1 PF00561.20 EPE31402.1 - 1.4e-18 67.5 0.0 3.2e-18 66.3 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EPE31402.1 - 1e-13 51.3 0.0 2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein DUF3484 PF11983.8 EPE31403.1 - 0.12 13.5 1.6 0.48 11.6 1.6 2.1 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch Glyco_transf_22 PF03901.17 EPE31404.1 - 9.1e-88 295.3 19.4 1.1e-87 295.0 19.4 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.14 EPE31405.1 - 2.5e-48 163.7 1.4 6.6e-48 162.4 1.4 1.7 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region API5 PF05918.11 EPE31405.1 - 0.96 8.2 6.4 2.4 6.9 6.4 1.6 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF3445 PF11927.8 EPE31406.1 - 1.2e-78 263.9 0.0 1.6e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Herpes_UL56 PF04534.12 EPE31406.1 - 0.043 13.3 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL56 protein BIR PF00653.21 EPE31408.1 - 5.7e-45 151.8 9.3 9e-22 77.5 0.1 2.4 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Rsm1 PF08600.10 EPE31408.1 - 0.0091 16.1 2.8 0.018 15.1 0.1 2.6 2 1 0 2 2 2 1 Rsm1-like zinc_ribbon_9 PF14369.6 EPE31408.1 - 0.069 13.4 0.9 11 6.4 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon zf-BED PF02892.15 EPE31408.1 - 0.069 13.2 0.5 1.2 9.2 0.0 2.7 3 0 0 3 3 3 0 BED zinc finger DUF4360 PF14273.6 EPE31409.1 - 4.6e-66 222.1 0.9 5.4e-66 221.9 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Pkinase PF00069.25 EPE31410.1 - 2e-43 148.7 0.0 2.7e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE31410.1 - 7.9e-21 74.5 0.0 1.2e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPE31410.1 - 0.014 14.2 0.1 0.049 12.4 0.0 1.8 1 1 1 2 2 2 0 Fungal protein kinase muHD PF10291.9 EPE31411.1 - 2.1e-64 217.5 0.0 3.2e-64 216.9 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 EPE31411.1 - 2.1e-08 34.3 0.1 6.7e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BAR_3 PF16746.5 EPE31411.1 - 2.7e-05 24.0 2.5 4.9e-05 23.2 2.5 1.3 1 0 0 1 1 1 1 BAR domain of APPL family Seryl_tRNA_N PF02403.22 EPE31411.1 - 2.2 8.6 5.0 4.2 7.6 0.8 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NUFIP1 PF10453.9 EPE31411.1 - 3.2 7.7 5.0 1.9 8.4 1.1 2.3 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) MAD PF05557.13 EPE31412.1 - 6.1e-61 206.6 60.9 8.3e-61 206.2 60.9 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Fib_alpha PF08702.10 EPE31412.1 - 0.036 14.2 0.2 0.036 14.2 0.2 6.2 5 1 3 8 8 8 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 EPE31412.1 - 0.2 12.1 0.1 0.2 12.1 0.1 8.6 9 1 1 10 10 10 0 Flagella accessory protein C (FlaC) Tam41_Mmp37 PF09139.11 EPE31413.1 - 2.2e-38 132.5 0.0 2.6e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial ABC_membrane PF00664.23 EPE31414.1 - 1.3e-88 297.2 44.3 8.1e-47 160.1 12.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region p450 PF00067.22 EPE31414.1 - 1.1e-62 212.3 0.0 1.6e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.27 EPE31414.1 - 4.9e-59 198.8 0.0 3.1e-32 112.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EPE31414.1 - 3.4e-12 46.3 5.0 0.00029 20.3 0.1 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EPE31414.1 - 2.8e-07 30.2 0.9 0.0063 16.2 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EPE31414.1 - 1e-06 29.3 3.1 0.091 13.1 1.6 3.9 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EPE31414.1 - 2e-06 27.8 0.2 0.12 12.3 0.0 3.2 3 0 0 3 3 2 2 RsgA GTPase ABC_ATPase PF09818.9 EPE31414.1 - 6e-05 22.0 1.1 0.14 11.0 0.1 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_15 PF13175.6 EPE31414.1 - 0.00015 21.6 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EPE31414.1 - 0.00021 21.8 0.1 0.26 11.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EPE31414.1 - 0.00026 21.3 1.0 0.24 11.7 0.0 3.2 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EPE31414.1 - 0.00038 20.2 0.7 0.51 10.0 0.1 3.6 3 1 0 3 3 3 1 AAA domain AAA_21 PF13304.6 EPE31414.1 - 0.00094 19.1 0.3 0.41 10.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 EPE31414.1 - 0.0013 18.0 0.0 0.58 9.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_5 PF07728.14 EPE31414.1 - 0.0017 18.4 0.1 1.2 9.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 EPE31414.1 - 0.0031 17.7 3.3 3 8.1 0.3 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 EPE31414.1 - 0.0052 16.1 0.3 0.54 9.5 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin ATP-synt_ab PF00006.25 EPE31414.1 - 0.012 15.3 0.1 0.48 10.1 0.0 3.0 3 1 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.6 EPE31414.1 - 0.014 15.0 0.8 2.9 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EPE31414.1 - 0.035 14.2 0.2 5 7.1 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 EPE31414.1 - 0.045 13.3 0.0 6.8 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 EPE31414.1 - 0.056 14.0 0.0 3.3 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EPE31414.1 - 0.13 12.5 0.0 21 5.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EPE31414.1 - 0.15 12.3 0.4 0.83 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EPE31414.1 - 0.16 11.7 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 EPE31414.1 - 0.18 11.0 0.3 4.7 6.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF4191 PF13829.6 EPE31414.1 - 0.34 10.2 2.0 1.1 8.5 2.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) NACHT PF05729.12 EPE31414.1 - 0.49 10.3 2.1 18 5.2 0.0 3.2 3 0 0 3 3 3 0 NACHT domain MMR_HSR1 PF01926.23 EPE31414.1 - 0.56 10.3 2.1 16 5.6 0.0 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase Aldose_epim PF01263.20 EPE31415.1 - 5.8e-30 104.6 0.1 7.1e-30 104.3 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4421 PF14391.6 EPE31416.1 - 0.053 12.9 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4421) ADH_zinc_N PF00107.26 EPE31417.1 - 1.3e-11 44.6 0.0 4e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE31417.1 - 0.008 16.0 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EPE31417.1 - 0.01 15.7 0.0 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase S1 PF00575.23 EPE31417.1 - 0.016 15.5 0.0 0.11 12.8 0.0 2.1 2 0 0 2 2 2 0 S1 RNA binding domain AMP-binding PF00501.28 EPE31418.1 - 7.7e-75 252.1 0.0 4e-74 249.7 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 EPE31418.1 - 3.4e-59 200.7 0.0 7e-59 199.7 0.0 1.4 1 0 0 1 1 1 1 Condensation domain ketoacyl-synt PF00109.26 EPE31418.1 - 4.7e-55 186.9 0.0 1.2e-54 185.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EPE31418.1 - 1e-48 165.6 0.4 2e-48 164.7 0.4 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EPE31418.1 - 2e-47 161.9 0.0 3.4e-47 161.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EPE31418.1 - 1.7e-45 156.0 0.0 3.8e-45 154.8 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE31418.1 - 6.5e-22 77.8 0.3 2.1e-21 76.1 0.3 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EPE31418.1 - 4.7e-18 65.8 0.0 1.3e-17 64.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EPE31418.1 - 7.6e-15 55.3 0.0 1.8e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EPE31418.1 - 7.6e-15 55.0 9.4 8.3e-09 35.7 0.1 4.2 4 0 0 4 4 4 2 Phosphopantetheine attachment site adh_short PF00106.25 EPE31418.1 - 1.1e-14 54.4 1.5 2.1e-14 53.5 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.12 EPE31418.1 - 1.7e-11 44.6 0.0 3.5e-10 40.4 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE31418.1 - 2.2e-11 44.3 0.0 1.4e-10 41.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE31418.1 - 3.4e-11 43.3 0.0 1.7e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE31418.1 - 9.2e-09 35.3 0.0 8.3e-08 32.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE31418.1 - 0.00015 21.1 0.0 0.00035 20.0 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EPE31418.1 - 0.021 14.4 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 EPE31418.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase SAT PF16073.5 EPE31418.1 - 0.11 12.3 1.2 0.21 11.3 0.2 2.1 2 1 0 2 2 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_N PF00108.23 EPE31418.1 - 0.15 11.4 0.4 0.34 10.2 0.4 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_33 PF10017.9 EPE31418.1 - 0.2 10.8 0.0 0.37 9.9 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Zn_clus PF00172.18 EPE31419.1 - 1.2e-07 31.8 7.0 2.1e-07 31.0 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1415 PF07209.12 EPE31419.1 - 0.07 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) SesA PF17107.5 EPE31420.1 - 2.3e-05 24.5 0.5 4.5e-05 23.6 0.5 1.4 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_4 PF13637.6 EPE31420.1 - 0.0022 18.5 0.2 1.1 9.9 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE31420.1 - 0.0037 17.8 0.1 0.067 13.8 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE31420.1 - 0.015 15.7 0.0 0.54 11.0 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat V-SNARE PF05008.15 EPE31420.1 - 0.044 14.1 0.7 0.32 11.4 0.4 2.5 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Ank PF00023.30 EPE31420.1 - 0.073 13.5 0.1 3.2 8.4 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat PRKCSH-like PF12999.7 EPE31420.1 - 0.11 12.3 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Glucosidase II beta subunit-like TP_methylase PF00590.20 EPE31423.1 - 9e-21 74.8 0.1 1.9e-20 73.7 0.1 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.8 EPE31424.1 - 1.1e-06 28.8 0.1 1.7e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPE31424.1 - 1.9e-05 24.9 0.3 3.3e-05 24.1 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 EPE31424.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.2 2 0 0 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins Aminotran_1_2 PF00155.21 EPE31427.1 - 3.6e-62 210.7 0.0 4.2e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 EPE31427.1 - 0.2 10.5 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Allinase zf-CCHC_2 PF13696.6 EPE31428.1 - 0.00011 21.9 1.0 0.00011 21.9 1.0 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 EPE31429.1 - 0.0007 19.4 3.7 0.00078 19.2 1.3 2.1 2 0 0 2 2 2 1 Zinc knuckle Epimerase PF01370.21 EPE31430.1 - 5.7e-16 58.7 0.0 1.5e-15 57.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EPE31430.1 - 1.7e-08 34.0 0.0 3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EPE31430.1 - 1.5e-05 24.2 0.0 4.1e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EPE31430.1 - 0.00011 21.7 0.0 0.00062 19.3 0.0 2.1 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EPE31430.1 - 0.035 13.5 0.1 6 6.3 0.0 2.6 2 1 0 2 2 2 0 short chain dehydrogenase SIT PF15330.6 EPE31431.1 - 0.042 14.3 0.0 0.058 13.8 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT FixQ PF05545.11 EPE31431.1 - 0.049 13.6 0.0 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ CMD PF02627.20 EPE31432.1 - 3.5e-06 27.0 0.0 5.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DUF1751 PF08551.10 EPE31432.1 - 0.056 14.0 0.3 1.7 9.2 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) DAO PF01266.24 EPE31433.1 - 1.5e-31 110.3 0.3 1.7e-31 110.1 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EPE31433.1 - 1.3e-05 24.6 0.0 1.3e-05 24.6 0.0 1.9 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.6 EPE31433.1 - 0.00023 21.3 0.0 0.00068 19.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE31433.1 - 0.023 13.8 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 EPE31433.1 - 0.034 13.0 0.1 1.7 7.4 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 EPE31433.1 - 0.061 12.5 0.0 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EPE31433.1 - 0.12 11.6 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain EHN PF06441.12 EPE31434.1 - 5.5e-33 113.6 0.8 7.4e-32 109.9 0.1 2.3 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EPE31434.1 - 7.7e-10 38.8 0.1 1.7e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE31434.1 - 6.5e-05 23.6 0.7 0.00044 20.9 0.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Haem_degrading PF03928.14 EPE31435.1 - 9.1e-29 99.9 2.1 1e-28 99.7 2.1 1.0 1 0 0 1 1 1 1 Haem-degrading Glyco_trans_1_4 PF13692.6 EPE31436.1 - 3.3e-09 37.3 0.0 1.3e-06 28.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Cation_efflux PF01545.21 EPE31437.1 - 3.1e-47 160.9 0.3 4.9e-47 160.3 0.3 1.3 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 EPE31437.1 - 0.00089 18.6 16.5 0.00089 18.6 16.5 3.8 2 1 0 2 2 2 1 ZIP Zinc transporter Anoctamin PF04547.12 EPE31437.1 - 0.39 9.5 2.4 0.2 10.5 0.1 1.6 2 0 0 2 2 2 0 Calcium-activated chloride channel Thioredoxin_5 PF13743.6 EPE31438.1 - 0.92 9.2 4.1 2.4 7.8 4.1 1.6 1 0 0 1 1 1 0 Thioredoxin Fic_N PF13784.6 EPE31440.1 - 1.3 9.1 4.8 5.1 7.2 0.2 3.4 3 0 0 3 3 3 0 Fic/DOC family N-terminal UQ_con PF00179.26 EPE31441.1 - 3.5e-33 114.2 0.0 4.1e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPE31441.1 - 0.082 12.6 0.1 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B Chromo PF00385.24 EPE31442.1 - 0.092 12.7 0.3 0.23 11.4 0.3 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain HD PF01966.22 EPE31443.1 - 1e-06 29.0 0.1 1.4e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 HD domain DNA_pol_phi PF04931.13 EPE31444.1 - 0.31 9.1 8.2 0.49 8.4 8.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi ER-remodelling PF14755.6 EPE31444.1 - 7.9 6.8 7.4 14 6.0 0.5 2.7 2 1 0 2 2 2 0 Intracellular membrane remodeller O-FucT PF10250.9 EPE31448.1 - 0.00047 20.0 0.0 0.0023 17.7 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Pex14_N PF04695.13 EPE31449.1 - 0.039 14.6 4.8 0.042 14.5 4.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4521 PF15021.6 EPE31449.1 - 0.079 12.9 2.7 0.087 12.7 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) GATase PF00117.28 EPE31450.1 - 1.6e-05 24.8 0.0 2.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EPE31450.1 - 0.19 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Med4 PF10018.9 EPE31451.1 - 5e-37 127.5 5.2 7.6e-37 126.9 5.2 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 U1snRNP70_N PF12220.8 EPE31451.1 - 0.25 12.0 2.5 0.46 11.1 0.4 2.5 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Hemerythrin PF01814.23 EPE31452.1 - 4.2e-07 30.7 1.4 6.5e-07 30.0 1.4 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain EF-hand_7 PF13499.6 EPE31453.1 - 8.5e-25 87.0 8.1 1.5e-15 57.4 0.6 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EPE31453.1 - 1.3e-24 84.0 4.3 3.8e-06 26.4 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_1 PF00036.32 EPE31453.1 - 1.7e-24 83.5 13.3 3.4e-08 32.5 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.6 EPE31453.1 - 1.9e-17 61.9 13.5 4.7e-05 22.7 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 EPE31453.1 - 4.4e-14 52.1 12.3 3e-05 23.8 1.0 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EPE31453.1 - 1.6e-09 37.6 7.7 0.0022 17.9 0.1 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EPE31453.1 - 2.1e-05 24.8 0.7 0.0068 16.7 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EPE31453.1 - 0.00078 19.7 3.0 0.97 9.8 0.4 3.1 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 EPE31453.1 - 0.0057 15.6 0.9 0.21 10.4 0.2 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF1679) EF-hand_10 PF14788.6 EPE31453.1 - 0.11 12.3 4.7 0.44 10.4 0.1 3.5 5 0 0 5 5 5 0 EF hand EF-hand_14 PF17959.1 EPE31453.1 - 0.21 12.0 2.8 6.7 7.1 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain LigB PF02900.18 EPE31454.1 - 4.6e-34 117.7 0.0 5.6e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short PF00106.25 EPE31456.1 - 1.6e-43 148.4 3.5 4e-43 147.1 3.5 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE31456.1 - 1.2e-40 139.5 3.3 4e-40 137.8 3.3 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE31456.1 - 7.5e-09 35.7 1.5 7.5e-09 35.7 1.5 1.6 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 EPE31456.1 - 0.00026 21.0 0.4 0.00044 20.2 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EPE31456.1 - 0.0041 16.6 2.6 0.031 13.7 2.6 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EPE31456.1 - 0.088 12.9 0.4 0.15 12.1 0.4 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 EPE31459.1 - 1.9e-15 56.3 0.0 1.6e-14 53.3 0.0 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EPE31459.1 - 2.3e-13 50.1 0.6 1.1e-11 44.6 1.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPE31459.1 - 6.3e-11 42.0 0.0 2.1e-10 40.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPE31459.1 - 6.5e-10 38.7 0.3 2.2e-07 30.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EPE31459.1 - 9.2e-08 32.2 0.9 5.8e-07 29.6 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EPE31459.1 - 9.6e-07 29.3 1.2 0.04 14.5 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE31459.1 - 1.5e-05 24.7 1.9 0.0092 15.6 2.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EPE31459.1 - 0.00055 19.3 0.4 0.024 13.9 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EPE31459.1 - 0.0019 18.2 1.0 0.045 13.7 0.1 2.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EPE31459.1 - 0.0068 16.5 0.1 5.2 7.1 0.0 2.6 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EPE31459.1 - 0.0079 16.1 0.2 0.013 15.4 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EPE31459.1 - 0.012 14.4 1.0 0.19 10.4 0.2 2.6 3 0 0 3 3 3 0 HI0933-like protein FAD_oxidored PF12831.7 EPE31459.1 - 0.053 12.9 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 EPE31459.1 - 0.07 12.5 0.0 13 5.1 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EPE31459.1 - 0.097 11.7 3.0 0.049 12.7 0.8 1.5 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EPE31459.1 - 0.15 11.1 0.0 0.36 9.8 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 EPE31459.1 - 5.6 5.9 6.4 0.25 10.4 0.7 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A EMP70 PF02990.16 EPE31461.1 - 1.5e-209 697.0 5.4 2e-209 696.6 5.4 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DUF3920 PF13058.6 EPE31461.1 - 0.023 14.9 0.0 0.067 13.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3920) Sas10_Utp3 PF04000.15 EPE31462.1 - 6e-17 62.0 1.4 6e-17 62.0 1.4 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Mito_carr PF00153.27 EPE31463.1 - 1.3e-58 194.9 3.4 1.9e-19 69.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PBP-Tp47_a PF14889.6 EPE31463.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a Pkinase_fungal PF17667.1 EPE31464.1 - 8.7e-108 360.7 0.0 2e-107 359.5 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EPE31464.1 - 0.0009 18.7 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain GAS PF13851.6 EPE31465.1 - 0.013 14.8 9.7 0.45 9.8 1.7 3.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 EPE31465.1 - 0.12 12.5 29.5 0.58 10.2 0.1 7.7 4 3 4 9 9 9 0 Protein of unknown function (DUF1664) DUF2730 PF10805.8 EPE31465.1 - 0.76 9.9 7.3 1.4 9.1 1.0 4.6 4 1 1 5 5 5 0 Protein of unknown function (DUF2730) HTH_Tnp_Mu_1 PF02316.16 EPE31465.1 - 1.2 9.4 5.3 5.2 7.2 0.6 3.2 2 0 0 2 2 2 0 Mu DNA-binding domain ADIP PF11559.8 EPE31465.1 - 5.4 7.1 10.7 0.22 11.6 0.4 3.5 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding CorA PF01544.18 EPE31466.1 - 8.6e-10 38.4 0.2 2.1e-09 37.2 0.2 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Cep57_CLD_2 PF14197.6 EPE31466.1 - 0.22 11.6 2.0 4.3 7.5 0.4 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ABC2_membrane PF01061.24 EPE31466.1 - 0.38 10.1 5.9 0.59 9.5 5.9 1.2 1 0 0 1 1 1 0 ABC-2 type transporter His_Phos_1 PF00300.22 EPE31467.1 - 1.4e-06 28.1 0.1 0.048 13.3 0.0 4.1 4 0 0 4 4 4 3 Histidine phosphatase superfamily (branch 1) Peptidase_C13 PF01650.18 EPE31468.1 - 2.3e-41 142.0 0.1 3.2e-41 141.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family ELF PF03317.13 EPE31468.1 - 0.089 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 ELF protein Serinc PF03348.15 EPE31469.1 - 2.2e-165 550.7 8.7 2.6e-165 550.6 8.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Nodulin-like PF06813.13 EPE31470.1 - 3.7e-14 52.8 4.2 8.1e-14 51.7 4.2 1.5 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 EPE31470.1 - 3.7e-14 52.4 35.7 2.9e-13 49.5 34.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2518 PF10726.9 EPE31470.1 - 0.28 10.8 1.1 0.95 9.1 1.1 1.9 1 0 0 1 1 1 0 Protein of function (DUF2518) PGAP1 PF07819.13 EPE31471.1 - 1.4e-92 309.6 0.0 2.3e-92 308.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EPE31471.1 - 8.4e-06 26.5 0.3 2.6e-05 24.9 0.3 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE31471.1 - 0.0048 16.2 0.0 0.0092 15.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE31471.1 - 0.011 15.4 0.1 0.032 13.9 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 EPE31471.1 - 0.025 14.4 0.0 0.04 13.7 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 EPE31471.1 - 0.044 13.3 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 EPE31471.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase adh_short_C2 PF13561.6 EPE31472.1 - 3.1e-60 203.6 0.0 4.1e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE31472.1 - 1.9e-51 174.3 0.2 2.4e-51 174.0 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE31472.1 - 8.9e-06 25.7 0.0 1.6e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE31472.1 - 0.0011 18.5 0.1 0.0029 17.1 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 EPE31472.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AAA PF00004.29 EPE31473.1 - 6.4e-37 126.9 0.0 1.6e-36 125.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE31473.1 - 4.2e-06 27.2 0.2 0.00054 20.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EPE31473.1 - 1.5e-05 25.1 0.0 4.3e-05 23.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_lid_3 PF17862.1 EPE31473.1 - 1.8e-05 24.5 0.0 3.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EPE31473.1 - 3.9e-05 23.7 0.2 0.00061 19.8 0.2 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EPE31473.1 - 4e-05 23.4 0.0 8.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EPE31473.1 - 8.7e-05 22.7 0.0 0.00027 21.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EPE31473.1 - 0.0002 21.7 0.2 0.0031 17.8 0.1 2.6 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EPE31473.1 - 0.00054 19.9 0.2 0.015 15.2 0.0 2.5 2 1 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 EPE31473.1 - 0.00054 20.1 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EPE31473.1 - 0.00059 19.6 0.0 0.00095 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EPE31473.1 - 0.00096 18.6 0.1 0.002 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EPE31473.1 - 0.0013 19.2 0.0 0.0032 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EPE31473.1 - 0.0015 18.9 0.0 0.0045 17.4 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_25 PF13481.6 EPE31473.1 - 0.003 17.1 0.1 0.032 13.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EPE31473.1 - 0.0042 16.5 0.0 3.1 7.1 0.0 2.4 1 1 0 2 2 2 2 Bacterial TniB protein Sigma54_activat PF00158.26 EPE31473.1 - 0.009 15.7 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.6 EPE31473.1 - 0.0091 15.7 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EPE31473.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EPE31473.1 - 0.011 15.7 0.1 0.025 14.5 0.1 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 EPE31473.1 - 0.012 15.8 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EPE31473.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 EPE31473.1 - 0.019 15.4 0.0 0.054 14.0 0.0 1.9 1 1 0 1 1 1 0 ABC transporter DUF815 PF05673.13 EPE31473.1 - 0.037 13.2 0.9 0.094 11.9 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.21 EPE31473.1 - 0.04 13.6 0.0 1.7 8.3 0.0 2.9 2 1 2 4 4 4 0 Guanylate kinase CPT PF07931.12 EPE31473.1 - 0.045 13.6 0.1 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 EPE31473.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EPE31473.1 - 0.061 13.2 0.0 0.25 11.2 0.0 1.8 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 EPE31473.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EPE31473.1 - 0.079 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EPE31473.1 - 0.098 11.8 0.0 0.59 9.3 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 EPE31473.1 - 0.099 12.0 0.3 1.4 8.2 0.0 2.6 2 1 1 3 3 3 0 KaiC AAA_21 PF13304.6 EPE31473.1 - 0.12 12.2 0.3 8.1 6.1 0.0 2.5 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system CH PF00307.31 EPE31474.1 - 6.3e-45 151.8 0.2 1.7e-22 79.7 0.0 2.9 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EPE31474.1 - 1.6e-23 82.6 0.3 2.8e-22 78.6 0.0 2.6 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EPE31474.1 - 3.2e-11 42.9 0.3 1.4e-06 28.1 0.1 2.6 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 EPE31474.1 - 0.00057 19.6 0.1 0.0043 16.9 0.0 2.7 3 0 0 3 3 2 1 EF-hand domain E2R135 PF11570.8 EPE31474.1 - 0.0098 16.2 1.4 1.9 8.8 0.3 2.9 2 1 0 2 2 2 1 Coiled-coil receptor-binding R-domain of colicin E2 EIAV_Rev PF11129.8 EPE31474.1 - 0.025 14.8 2.1 0.085 13.1 2.1 1.8 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus EF-hand_1 PF00036.32 EPE31474.1 - 0.039 13.5 0.3 0.74 9.5 0.0 3.0 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 EPE31474.1 - 0.065 13.1 0.8 2.2 8.2 0.1 3.4 3 1 1 4 4 4 0 EF-hand domain pair CH_2 PF06294.11 EPE31474.1 - 0.065 13.4 0.0 3.4 7.8 0.0 2.9 2 1 0 2 2 2 0 CH-like domain in sperm protein Spectrin PF00435.21 EPE31474.1 - 0.098 13.2 3.5 2.7 8.5 0.1 2.7 2 0 0 2 2 2 0 Spectrin repeat EF-hand_7 PF13499.6 EPE31474.1 - 0.12 12.9 4.3 0.08 13.4 1.4 2.4 2 0 0 2 2 2 0 EF-hand domain pair DUF4508 PF14969.6 EPE31474.1 - 0.85 9.9 3.7 4 7.8 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) FliG_N PF14842.6 EPE31474.1 - 1.3 9.6 3.7 3.1 8.4 0.1 2.9 3 0 0 3 3 3 0 FliG N-terminal domain HMMR_N PF15905.5 EPE31474.1 - 2.1 7.7 4.6 2.5 7.5 0.2 2.3 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Dynamin_N PF00350.23 EPE31475.1 - 1e-32 113.5 0.1 2.8e-32 112.1 0.1 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EPE31475.1 - 8.1e-22 77.8 0.1 8.3e-21 74.4 0.0 2.2 1 1 1 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EPE31475.1 - 8.2e-05 22.7 0.6 0.00068 19.7 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.18 EPE31475.1 - 0.0042 17.2 4.0 0.011 15.8 0.6 3.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain CheZ PF04344.13 EPE31475.1 - 0.016 15.1 1.1 0.067 13.1 0.0 2.5 3 0 0 3 3 3 0 Chemotaxis phosphatase, CheZ AAA_15 PF13175.6 EPE31475.1 - 0.048 13.4 0.1 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF2478 PF10649.9 EPE31475.1 - 0.057 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) Peptidase_M75 PF09375.10 EPE31475.1 - 0.057 12.9 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Imelysin AAA_29 PF13555.6 EPE31475.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Methyltransf_11 PF08241.12 EPE31479.1 - 4e-10 40.2 0.0 6.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE31479.1 - 1.6e-09 38.4 0.0 2.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE31479.1 - 6.8e-06 26.0 0.0 9.2e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE31479.1 - 1e-05 25.4 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE31479.1 - 4.2e-05 24.2 0.0 6.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Myb_DNA-binding PF00249.31 EPE31480.1 - 5.1e-14 52.2 2.8 1.5e-10 41.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPE31480.1 - 9.7e-07 29.0 2.3 0.0053 17.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Sporozoite_P67 PF05642.11 EPE31480.1 - 0.14 10.2 1.3 0.19 9.8 1.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ubiquitin_2 PF14560.6 EPE31482.1 - 2.1e-17 63.4 0.0 3.4e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 EPE31482.1 - 0.00017 21.3 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family CAP_GLY PF01302.25 EPE31483.1 - 1.5e-18 66.5 3.4 2.1e-18 66.1 3.4 1.2 1 0 0 1 1 1 1 CAP-Gly domain DUF726 PF05277.12 EPE31484.1 - 9.8e-118 393.0 0.9 1.4e-117 392.5 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 EPE31484.1 - 0.00032 20.9 0.0 0.0011 19.2 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain tRNA-synt_2d PF01409.20 EPE31484.1 - 0.45 10.0 1.3 1.4 8.3 0.2 1.9 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Transp_cyt_pur PF02133.15 EPE31485.1 - 2.2e-106 356.3 38.0 2.7e-106 356.0 38.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Bac_export_2 PF01312.19 EPE31485.1 - 4.2 6.5 6.6 10 5.2 6.6 1.6 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family S1FA PF04689.13 EPE31485.1 - 7.4 6.8 8.2 0.14 12.3 0.5 2.1 2 0 0 2 2 2 0 DNA binding protein S1FA AMP-binding PF00501.28 EPE31486.1 - 2.1e-23 82.6 0.0 9.9e-23 80.4 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EPE31486.1 - 5.1e-20 71.7 0.0 9.9e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EPE31486.1 - 1.1e-09 38.6 0.0 2.7e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EPE31486.1 - 3.7e-05 23.3 0.0 7.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EPE31486.1 - 0.014 15.9 0.0 0.031 14.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 EPE31486.1 - 0.015 16.0 0.0 0.046 14.4 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase zf-RING_2 PF13639.6 EPE31487.1 - 1.6e-12 47.5 4.1 2.5e-12 46.9 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EPE31487.1 - 2.3e-10 40.0 1.2 4.6e-10 39.1 1.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EPE31487.1 - 5.1e-07 29.4 4.1 8.4e-07 28.7 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE31487.1 - 9.3e-07 28.6 3.6 1.5e-06 28.0 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPE31487.1 - 1.4e-06 28.5 4.3 3.5e-06 27.2 4.3 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EPE31487.1 - 2.6e-05 24.0 3.7 4.5e-05 23.2 3.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EPE31487.1 - 5.4e-05 23.1 2.7 8.4e-05 22.4 2.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EPE31487.1 - 0.00097 19.0 1.2 0.0016 18.3 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EPE31487.1 - 0.003 17.6 0.5 0.0054 16.7 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EPE31487.1 - 0.013 15.5 6.0 0.026 14.6 6.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 EPE31487.1 - 0.017 14.9 3.1 0.027 14.2 3.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 EPE31487.1 - 0.082 12.9 3.6 0.21 11.5 1.6 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 EPE31487.1 - 0.094 12.9 2.7 0.97 9.7 2.7 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EPE31487.1 - 0.22 11.9 1.8 0.35 11.2 1.8 1.3 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 EPE31487.1 - 0.41 10.6 3.2 0.8 9.7 3.2 1.5 1 0 0 1 1 1 0 PHD-finger SpoIIIAH PF12685.7 EPE31487.1 - 0.92 9.3 4.9 6.4 6.5 4.9 2.2 1 1 0 1 1 1 0 SpoIIIAH-like protein SKG6 PF08693.10 EPE31488.1 - 0.045 13.2 0.5 0.084 12.3 0.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MMU163 PF17119.5 EPE31489.1 - 3.7e-83 278.5 7.4 5.5e-61 205.9 1.6 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis Ras PF00071.22 EPE31490.1 - 1.7e-65 219.6 0.5 2e-65 219.3 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE31490.1 - 6.7e-36 123.1 0.1 1.2e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE31490.1 - 3e-16 59.4 0.1 3.6e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPE31490.1 - 1.8e-05 24.8 0.0 9.8e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPE31490.1 - 2.2e-05 24.4 0.3 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EPE31490.1 - 8.5e-05 22.2 0.4 0.00023 20.7 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EPE31490.1 - 0.00026 20.4 0.1 0.00033 20.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EPE31490.1 - 0.00046 19.7 0.0 0.00069 19.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 EPE31490.1 - 0.00083 19.8 0.1 0.16 12.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 EPE31490.1 - 0.0042 16.6 0.0 0.025 14.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EPE31490.1 - 0.0088 16.4 0.0 0.012 16.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPE31490.1 - 0.036 14.3 0.0 0.067 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EPE31490.1 - 0.056 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 EPE31490.1 - 0.059 13.4 0.1 0.13 12.3 0.0 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 EPE31490.1 - 0.071 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Septin PF00735.18 EPE31490.1 - 0.073 12.3 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 EPE31490.1 - 0.083 13.4 0.0 0.15 12.6 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EPE31490.1 - 0.083 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 EPE31490.1 - 0.1 12.3 0.1 1.2 8.8 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 EPE31490.1 - 0.12 11.9 0.1 1.5 8.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain WD40 PF00400.32 EPE31492.1 - 7.1e-11 42.5 16.1 0.36 11.8 0.5 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.6 EPE31492.1 - 0.033 14.7 1.1 0.24 12.0 0.1 3.1 3 0 0 3 3 3 0 PQQ-like domain DUF1647 PF07801.11 EPE31492.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) Mcl1_mid PF12341.8 EPE31493.1 - 2e-97 326.1 0.0 6.1e-97 324.5 0.0 1.8 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EPE31493.1 - 3.9e-18 65.5 3.3 4.1e-05 24.3 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE31493.1 - 1.9e-13 50.5 0.0 0.0097 16.2 0.1 7.2 2 1 6 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EPE31493.1 - 1.2e-08 34.5 0.0 2.6e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.11 EPE31493.1 - 0.00044 20.2 0.8 0.021 14.7 0.1 3.1 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EPE31493.1 - 0.018 14.9 0.1 1e+02 3.0 0.0 4.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DNA_pol_alpha_N PF12254.8 EPE31493.1 - 0.085 13.0 2.0 0.19 11.8 2.0 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal FCD PF07729.12 EPE31494.1 - 1.3 9.5 5.0 1.1 9.7 2.3 2.2 2 0 0 2 2 2 0 FCD domain DUF2408 PF10303.9 EPE31494.1 - 8.4 7.0 18.3 2 8.9 8.9 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) Beta_elim_lyase PF01212.21 EPE31495.1 - 1.2e-71 241.4 0.0 1.5e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EPE31495.1 - 0.018 14.2 0.0 0.031 13.4 0.0 1.4 2 0 0 2 2 2 0 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EPE31495.1 - 0.028 12.9 0.0 0.051 12.1 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme adh_short PF00106.25 EPE31496.1 - 3.8e-53 179.9 1.0 4.5e-53 179.6 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE31496.1 - 1.2e-50 172.3 0.6 1.7e-50 171.8 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE31496.1 - 7.4e-11 42.3 0.6 9.9e-11 41.9 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE31496.1 - 0.021 14.3 0.3 0.06 12.8 0.3 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HHH_5 PF14520.6 EPE31496.1 - 0.19 12.4 3.3 7.9 7.2 0.3 3.3 1 1 2 3 3 3 0 Helix-hairpin-helix domain DUF4360 PF14273.6 EPE31497.1 - 2e-43 148.3 1.1 2.4e-43 148.1 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) SSP160 PF06933.11 EPE31499.1 - 0.45 8.7 6.0 0.59 8.3 6.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HeLo PF14479.6 EPE31501.1 - 9.2e-23 81.1 0.8 1.4e-22 80.6 0.3 1.5 2 0 0 2 2 2 1 Prion-inhibition and propagation GIT_SHD PF08518.11 EPE31501.1 - 6.4e-19 67.3 10.7 3.2e-13 49.0 0.8 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT RA PF00788.23 EPE31501.1 - 8.2e-14 52.0 0.0 1.6e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain TUG-UBL1 PF11470.8 EPE31501.1 - 0.0032 17.6 0.0 0.0082 16.3 0.0 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain PLL PF18587.1 EPE31501.1 - 0.033 14.3 0.0 0.071 13.3 0.0 1.5 1 0 0 1 1 1 0 PTX/LNS-Like (PLL) domain SnoaL_2 PF12680.7 EPE31503.1 - 0.0014 19.2 0.0 0.0089 16.7 0.0 2.2 2 0 0 2 2 2 1 SnoaL-like domain adh_short PF00106.25 EPE31504.1 - 2.3e-26 92.5 0.2 3.9e-26 91.7 0.2 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE31504.1 - 1.4e-18 67.3 0.1 1.9e-18 66.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE31504.1 - 1.4e-08 34.9 0.1 1.6e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE31504.1 - 0.00017 20.8 0.1 0.00025 20.3 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_transf_28 PF03033.20 EPE31505.1 - 2.9e-22 79.2 0.0 6.1e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EPE31505.1 - 1.2e-06 27.6 0.0 2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase AAA PF00004.29 EPE31508.1 - 3.6e-51 173.0 0.0 5.5e-43 146.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE31508.1 - 1.1e-05 25.9 0.0 0.019 15.3 0.0 3.7 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EPE31508.1 - 0.00012 21.9 0.0 0.00045 20.0 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 EPE31508.1 - 0.00053 19.2 0.0 0.00092 18.4 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 EPE31508.1 - 0.0012 19.2 0.0 0.015 15.7 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.14 EPE31508.1 - 0.0023 18.1 0.0 0.0092 16.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 EPE31508.1 - 0.0047 16.7 1.6 0.52 10.1 0.0 2.8 2 0 0 2 2 2 1 AAA+ lid domain TIP49 PF06068.13 EPE31508.1 - 0.005 16.1 0.1 0.011 15.0 0.0 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_25 PF13481.6 EPE31508.1 - 0.0061 16.2 0.7 0.05 13.2 0.0 2.8 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EPE31508.1 - 0.008 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EPE31508.1 - 0.0099 16.2 0.0 0.043 14.1 0.0 2.0 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EPE31508.1 - 0.015 14.7 0.4 0.049 13.0 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EPE31508.1 - 0.018 15.2 0.0 0.43 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EPE31508.1 - 0.019 15.0 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EPE31508.1 - 0.032 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EPE31508.1 - 0.034 14.1 0.0 0.12 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 EPE31508.1 - 0.039 13.3 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 EPE31508.1 - 0.05 14.2 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EPE31508.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein TetR_C_32 PF09209.11 EPE31508.1 - 0.13 12.3 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AAA_28 PF13521.6 EPE31508.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EPE31508.1 - 0.17 11.9 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Abhydro_lipase PF04083.16 EPE31509.1 - 7e-16 57.6 0.0 1.3e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EPE31509.1 - 0.0012 18.2 0.0 0.0041 16.4 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE31509.1 - 0.0014 18.3 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold zf-RING_2 PF13639.6 EPE31510.1 - 1.3e-10 41.4 3.3 1.3e-10 41.4 3.3 3.2 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EPE31510.1 - 4e-10 39.6 0.7 4e-10 39.6 0.7 3.4 3 1 1 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EPE31510.1 - 4.2e-07 29.7 3.5 4.2e-07 29.7 3.5 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE31510.1 - 8.1e-07 28.9 3.1 8.1e-07 28.9 3.1 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_11 PF17123.5 EPE31510.1 - 1.5e-06 27.8 2.1 1.5e-06 27.8 2.1 2.8 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EPE31510.1 - 4.8e-06 26.3 1.9 4.8e-06 26.3 1.9 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE31510.1 - 1.1e-05 25.2 2.9 1.1e-05 25.2 2.9 2.7 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EPE31510.1 - 3.4e-05 23.9 10.6 7.2e-05 22.9 5.7 3.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EPE31510.1 - 0.00071 19.4 4.7 0.00071 19.4 4.7 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPE31510.1 - 0.00083 19.6 1.1 0.00083 19.6 1.1 2.7 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-Di19 PF05605.12 EPE31510.1 - 0.01 16.1 1.6 0.097 13.0 0.2 2.8 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 EPE31510.1 - 1.2 9.7 0.1 1.2 9.7 0.1 3.3 3 1 0 3 3 2 0 Zinc-finger double domain COesterase PF00135.28 EPE31511.1 - 1.2e-79 268.5 1.6 1.6e-69 235.1 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE31511.1 - 0.0027 17.6 0.0 0.0066 16.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DPPIV_N PF00930.21 EPE31514.1 - 2.1e-111 372.1 0.3 2.8e-111 371.7 0.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EPE31514.1 - 3.2e-56 190.1 2.4 6.6e-56 189.1 2.4 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EPE31514.1 - 6.3e-08 32.5 1.3 1e-06 28.6 0.3 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EPE31514.1 - 0.00026 21.7 0.2 0.064 13.8 0.0 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydro_lipase PF04083.16 EPE31514.1 - 0.0022 17.5 0.0 0.0067 16.0 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region PAF-AH_p_II PF03403.13 EPE31514.1 - 0.0049 15.4 0.0 0.62 8.5 0.0 2.2 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II DLH PF01738.18 EPE31514.1 - 0.025 14.1 0.0 0.11 12.1 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EPE31514.1 - 0.043 13.5 0.4 0.12 12.0 0.1 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.12 EPE31514.1 - 0.045 12.4 0.0 0.26 9.9 0.0 2.0 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF5050 PF16472.5 EPE31514.1 - 0.065 12.5 0.1 0.17 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) WEMBL PF05701.11 EPE31515.1 - 4.5e-05 22.4 25.5 5.9e-05 22.0 25.5 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF572 PF04502.13 EPE31515.1 - 0.049 13.3 15.7 0.062 12.9 15.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Carb_kinase PF01256.17 EPE31516.1 - 1.2e-56 192.0 0.0 1.6e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 EPE31516.1 - 0.033 13.6 0.0 0.13 11.6 0.0 1.9 1 1 0 2 2 2 0 Phosphomethylpyrimidine kinase Jiraiya PF15038.6 EPE31518.1 - 0.011 15.2 1.4 1.2 8.5 0.1 2.0 2 0 0 2 2 2 0 Jiraiya RHD3 PF05879.12 EPE31519.1 - 0 1035.4 0.0 0 1035.2 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EPE31519.1 - 3.1e-08 33.2 0.1 4.8e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 EPE31519.1 - 6.1e-06 26.4 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EPE31519.1 - 0.00028 20.9 0.0 0.00064 19.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EPE31519.1 - 0.0017 18.6 0.0 0.0055 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF3693 PF12472.8 EPE31519.1 - 0.11 12.1 0.1 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 Phage related protein AA_permease_2 PF13520.6 EPE31520.1 - 1.3e-61 208.8 59.3 1.5e-61 208.5 59.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE31520.1 - 2.2e-33 115.6 54.3 3e-33 115.2 54.3 1.0 1 0 0 1 1 1 1 Amino acid permease DPBB_1 PF03330.18 EPE31521.1 - 0.0002 21.5 0.1 0.00029 21.1 0.1 1.3 1 0 0 1 1 1 1 Lytic transglycolase Glyco_hydro_16 PF00722.21 EPE31522.1 - 2.1e-08 33.9 0.0 1.3e-07 31.2 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Toxin_13 PF07822.11 EPE31522.1 - 0.025 14.7 2.0 0.054 13.6 2.0 1.6 1 0 0 1 1 1 0 Neurotoxin B-IV-like protein Glyco_transf_34 PF05637.12 EPE31523.1 - 1.1e-62 211.9 0.4 1.7e-62 211.3 0.4 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Imm17 PF15562.6 EPE31524.1 - 0.19 11.6 2.2 0.41 10.5 2.2 1.5 1 0 0 1 1 1 0 Immunity protein 17 HET PF06985.11 EPE31525.1 - 3.3e-28 98.9 0.2 5.5e-28 98.2 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C3HC4 PF00097.25 EPE31525.1 - 1.9 8.4 5.3 4.6 7.2 5.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sortilin-Vps10 PF15902.5 EPE31526.1 - 5.3e-293 971.4 26.3 7e-148 493.1 16.1 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EPE31526.1 - 1.4e-91 305.4 20.1 2e-46 158.5 9.4 2.5 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EPE31526.1 - 5.7e-14 49.8 28.4 0.088 12.9 0.1 11.1 10 0 0 10 10 10 6 BNR/Asp-box repeat PSII_BNR PF14870.6 EPE31526.1 - 0.00064 19.1 0.3 1.1 8.5 0.0 4.4 4 0 0 4 4 4 1 Photosynthesis system II assembly factor YCF48 CHB_HEX_C PF03174.13 EPE31526.1 - 0.051 13.5 0.6 17 5.5 0.0 3.8 4 0 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain PA-IIL PF07472.11 EPE31526.1 - 0.14 12.5 0.2 1.6 9.1 0.0 2.8 4 0 0 4 4 4 0 Fucose-binding lectin II (PA-IIL) BNR_6 PF15899.5 EPE31526.1 - 0.49 10.6 16.5 0.35 11.0 0.1 6.7 7 0 0 7 7 7 0 BNR-Asp box repeat Phage_Gp15 PF06854.11 EPE31528.1 - 0.081 12.9 0.8 0.15 12.0 0.8 1.4 1 0 0 1 1 1 0 Bacteriophage Gp15 protein Glyco_hydro_53 PF07745.13 EPE31529.1 - 3.4e-79 266.3 0.0 4e-79 266.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Myb_DNA-bind_3 PF12776.7 EPE31529.1 - 0.095 13.7 0.0 0.19 12.7 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Mpv17_PMP22 PF04117.12 EPE31530.1 - 4.8e-21 74.8 0.1 4.8e-21 74.8 0.1 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.19 EPE31531.1 - 9.8e-145 482.2 2.4 1.1e-144 482.1 2.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3530 PF12048.8 EPE31531.1 - 0.032 13.7 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DSS1_SEM1 PF05160.13 EPE31532.1 - 5.3e-23 80.8 16.3 7.2e-23 80.4 16.3 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF3808 PF10300.9 EPE31533.1 - 4e-122 408.4 0.1 4.8e-122 408.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Orbi_VP5 PF00901.17 EPE31533.1 - 0.028 12.8 0.1 0.043 12.2 0.1 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF1240 PF06836.12 EPE31533.1 - 0.58 10.7 2.0 0.74 10.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) Fungal_trans PF04082.18 EPE31534.1 - 8.9e-18 64.3 0.0 1.4e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE31534.1 - 1e-06 28.7 13.1 1.7e-06 28.1 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PVL_ORF50 PF07768.11 EPE31534.1 - 0.36 11.1 1.4 0.51 10.7 0.1 1.9 2 0 0 2 2 2 0 PVL ORF-50-like family Fungal_trans PF04082.18 EPE31535.1 - 1.1e-17 64.0 0.4 1.5e-17 63.5 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE31535.1 - 1.9e-07 31.1 9.7 3.9e-07 30.1 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE31535.1 - 0.026 13.3 0.0 0.061 12.1 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain PRIMA1 PF16101.5 EPE31536.1 - 0.0024 17.9 1.1 0.0068 16.4 1.1 1.7 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Pex14_N PF04695.13 EPE31536.1 - 0.035 14.8 0.9 0.035 14.8 0.9 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SRI PF08236.11 EPE31536.1 - 0.037 14.2 0.1 0.11 12.7 0.1 1.8 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Gemini_mov PF01708.16 EPE31536.1 - 0.12 12.1 0.1 0.48 10.2 0.0 2.1 2 0 0 2 2 2 0 Geminivirus putative movement protein EphA2_TM PF14575.6 EPE31536.1 - 0.4 11.6 1.4 16 6.4 0.0 3.6 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Mre11_DNA_bind PF04152.14 EPE31536.1 - 0.68 10.2 5.1 0.54 10.6 0.1 2.5 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain SAPS PF04499.15 EPE31536.1 - 1.4 7.7 9.7 2.2 7.0 9.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SNF5 PF04855.12 EPE31537.1 - 7.7e-90 300.8 0.0 1.1e-89 300.4 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 EPE31537.1 - 0.0039 16.8 1.1 0.0087 15.7 1.1 1.6 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 EPE31537.1 - 0.74 9.6 4.5 9.7 6.0 0.8 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF3060 PF11259.8 EPE31538.1 - 0.0066 16.1 1.5 0.096 12.4 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3060) Glypican PF01153.19 EPE31538.1 - 0.092 11.6 2.2 0.1 11.4 2.2 1.1 1 0 0 1 1 1 0 Glypican Proteasom_Rpn13 PF04683.13 EPE31539.1 - 2.3e-27 95.4 0.0 3.5e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EPE31539.1 - 2.5e-10 40.5 0.4 4.9e-09 36.4 0.4 2.2 1 1 0 1 1 1 1 UCH-binding domain MoaF_C PF17409.2 EPE31539.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 MoaF C-terminal domain Ribosomal_L6e PF01159.19 EPE31540.1 - 6.2e-40 136.2 2.5 1.2e-39 135.3 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L6e GNAT_acetyltr_2 PF13718.6 EPE31540.1 - 0.14 11.5 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Peptidase_M49 PF03571.15 EPE31541.1 - 4.7e-243 807.6 0.0 5.7e-243 807.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 Ribosomal_L6 PF00347.23 EPE31542.1 - 1.9e-23 82.9 8.0 1.8e-12 47.7 0.4 3.1 3 0 0 3 3 3 3 Ribosomal protein L6 Acetyltransf_1 PF00583.25 EPE31543.1 - 1.2e-09 38.4 0.1 8.9e-09 35.6 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE31543.1 - 4.7e-08 33.0 0.0 5e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE31543.1 - 1.1e-06 28.9 0.1 1.8e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE31543.1 - 0.00028 20.8 0.0 0.00059 19.8 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EPE31543.1 - 0.0004 20.5 0.0 0.003 17.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPE31543.1 - 0.00045 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 EPE31543.1 - 0.0016 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_13 PF13880.6 EPE31543.1 - 0.04 13.9 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase RPA43_OB PF17875.1 EPE31543.1 - 1.8 9.2 3.6 18 6.0 3.6 2.0 1 1 0 1 1 1 0 RPA43 OB domain in RNA Pol I Ammonium_transp PF00909.21 EPE31545.1 - 4.6e-116 387.8 31.4 5.2e-116 387.6 31.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF441 PF04284.13 EPE31545.1 - 0.0054 16.8 0.5 0.032 14.2 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF441) DNA_pol_B_palm PF14792.6 EPE31546.1 - 9.5e-35 119.3 0.0 2.9e-34 117.7 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EPE31546.1 - 7.1e-22 77.4 0.1 1.6e-21 76.2 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EPE31546.1 - 7.4e-21 73.7 0.1 4.4e-20 71.3 0.1 2.2 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 EPE31546.1 - 3.3e-14 53.0 0.1 4.6e-13 49.3 0.1 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT PF00533.26 EPE31546.1 - 6.8e-05 23.2 0.0 0.00014 22.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.23 EPE31546.1 - 0.031 14.6 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain IMS_HHH PF11798.8 EPE31546.1 - 0.19 12.1 0.4 91 3.7 0.0 3.7 3 0 0 3 3 3 0 IMS family HHH motif Glutaredoxin PF00462.24 EPE31548.1 - 3.6e-14 52.7 0.0 2.5e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin MFS_1 PF07690.16 EPE31549.1 - 4.7e-39 134.3 37.0 4.7e-39 134.3 37.0 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EPE31549.1 - 0.12 10.6 13.9 0.22 9.8 5.4 3.4 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PP2C PF00481.21 EPE31550.1 - 1.7e-30 106.5 0.0 2.6e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EPE31550.1 - 0.036 14.0 0.0 9.2 6.1 0.0 2.7 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) CBFD_NFYB_HMF PF00808.23 EPE31551.1 - 7.3e-10 39.0 0.0 1.4e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 EPE31551.1 - 0.0042 17.2 0.0 0.0076 16.4 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIIA PF03153.13 EPE31551.1 - 0.021 14.9 16.6 0.027 14.5 16.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Histone PF00125.24 EPE31551.1 - 0.07 13.5 0.1 0.07 13.5 0.1 2.7 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EPE31551.1 - 0.14 12.5 0.0 0.14 12.5 0.0 2.8 3 1 0 3 3 3 0 CENP-S associating Centromere protein X PPP4R2 PF09184.11 EPE31551.1 - 1.3 8.5 14.2 1.8 8.1 14.2 1.3 1 0 0 1 1 1 0 PPP4R2 TMEM154 PF15102.6 EPE31552.1 - 0.16 11.9 2.4 0.98 9.3 2.4 2.3 1 1 0 1 1 1 0 TMEM154 protein family HRXXH PF13933.6 EPE31553.1 - 1.3e-06 28.2 0.6 0.0015 18.2 2.1 2.1 2 0 0 2 2 2 2 Putative peptidase family Aspzincin_M35 PF14521.6 EPE31553.1 - 0.0019 18.7 1.2 0.0056 17.2 1.2 1.9 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase Pkinase PF00069.25 EPE31554.1 - 8e-66 222.1 0.0 1.6e-65 221.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE31554.1 - 2.6e-36 125.3 0.0 4.7e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE31554.1 - 1.9e-06 27.5 0.0 3.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EPE31554.1 - 0.00019 20.4 0.0 0.00047 19.1 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EPE31554.1 - 0.007 16.3 0.0 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family SLD3 PF08639.10 EPE31555.1 - 2.8e-175 584.1 4.9 2.8e-175 584.1 4.9 2.0 2 0 0 2 2 2 1 DNA replication regulator SLD3 APH PF01636.23 EPE31555.1 - 2.2e-13 50.7 0.0 4.9e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Apq12 PF12716.7 EPE31556.1 - 6.7e-15 54.8 10.3 1.3e-14 53.8 10.3 1.5 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis vMSA PF00695.19 EPE31556.1 - 0.011 14.9 1.5 0.014 14.5 1.5 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus MerC PF03203.14 EPE31556.1 - 0.029 14.8 0.6 0.049 14.1 0.6 1.4 1 0 0 1 1 1 0 MerC mercury resistance protein ATP_bind_1 PF03029.17 EPE31557.1 - 1.1e-73 247.9 0.0 1.4e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EPE31557.1 - 1.1e-05 25.4 0.0 3.1e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 EPE31557.1 - 0.00061 19.8 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EPE31557.1 - 0.0015 19.0 0.0 0.0032 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EPE31557.1 - 0.0039 16.9 0.0 0.0088 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EPE31557.1 - 0.0056 17.1 0.0 0.01 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EPE31557.1 - 0.0087 16.4 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 EPE31557.1 - 0.0087 16.3 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EPE31557.1 - 0.013 15.6 0.0 0.047 13.8 0.0 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EPE31557.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EPE31557.1 - 0.029 13.9 0.0 8.3 5.9 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EPE31557.1 - 0.034 14.7 0.0 0.074 13.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 EPE31557.1 - 0.039 12.9 0.0 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 EPE31557.1 - 0.041 14.3 0.0 0.074 13.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EPE31557.1 - 0.044 13.3 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 EPE31557.1 - 0.046 12.8 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.23 EPE31557.1 - 0.056 13.5 0.0 0.074 13.1 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EPE31557.1 - 0.065 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EPE31557.1 - 0.076 12.2 0.0 0.12 11.6 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain ATPase PF06745.13 EPE31557.1 - 0.092 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 KaiC NTPase_1 PF03266.15 EPE31557.1 - 0.1 12.5 0.0 0.74 9.7 0.0 2.0 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 EPE31557.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 EPE31557.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 EPE31557.1 - 0.13 12.6 0.1 0.57 10.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EPE31557.1 - 0.13 12.2 0.0 0.51 10.2 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 EPE31557.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EPE31557.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain PPV_E1_C PF00519.17 EPE31557.1 - 0.25 10.1 0.0 0.38 9.5 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase S-AdoMet_synt_C PF02773.16 EPE31558.1 - 5.3e-66 220.8 0.9 1.3e-65 219.6 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EPE31558.1 - 4.6e-46 156.0 0.0 9.6e-46 154.9 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EPE31558.1 - 1.1e-43 147.9 0.6 2.8e-43 146.6 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EPE31558.1 - 0.12 11.2 0.4 0.68 8.7 0.1 2.0 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) DUF4376 PF14301.6 EPE31559.1 - 1.6 9.1 8.0 0.61 10.5 2.4 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) RIC1 PF07064.13 EPE31560.1 - 7.1e-96 320.5 0.1 9.7e-96 320.0 0.1 1.2 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 EPE31560.1 - 0.0014 18.9 0.0 6 7.3 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPE31560.1 - 0.023 15.6 2.0 2.1 9.3 0.3 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat WD40 PF00400.32 EPE31561.1 - 6.4e-23 80.6 8.2 6.4e-05 23.7 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE31561.1 - 2.5e-14 53.3 0.0 0.058 13.7 0.0 5.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EPE31561.1 - 0.00035 19.2 0.0 0.034 12.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 EPE31561.1 - 0.00069 19.6 0.1 0.17 11.7 0.1 3.6 3 2 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EPE31561.1 - 0.0017 17.1 0.2 0.13 10.8 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 EPE31561.1 - 0.013 14.6 0.0 2.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) DUF5114 PF17141.4 EPE31561.1 - 0.078 13.5 0.0 0.46 11.0 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5114) Arena_nucleocap PF00843.17 EPE31561.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Arenavirus nucleocapsid N-terminal domain Fungal_trans PF04082.18 EPE31562.1 - 5.2e-14 51.9 0.3 1.1e-13 50.8 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE31562.1 - 1.9e-09 37.5 9.7 3.8e-09 36.5 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L2_C PF03947.18 EPE31563.1 - 4.3e-51 172.4 1.8 1e-50 171.1 1.2 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EPE31563.1 - 3.8e-26 90.9 0.6 8e-26 89.8 0.6 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.23 EPE31564.1 - 5.7e-45 152.2 0.2 3.3e-44 149.7 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EPE31564.1 - 5.1e-37 126.6 0.1 8.8e-37 125.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain HEPN_Toprim_N PF18871.1 EPE31564.1 - 0.12 12.3 0.9 0.79 9.6 0.0 2.2 2 0 0 2 2 2 0 HEPN/Toprim N-terminal domain 1 MFS_1 PF07690.16 EPE31565.1 - 1.2e-29 103.3 41.8 1.1e-19 70.6 22.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE31565.1 - 8.7e-19 67.7 19.3 8.8e-18 64.4 19.3 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Ank_2 PF12796.7 EPE31566.1 - 1.6e-26 92.6 0.0 4.5e-15 56.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EPE31566.1 - 1.4e-15 56.9 0.1 0.00012 22.3 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EPE31566.1 - 9.1e-14 51.6 0.0 5.8e-08 33.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE31566.1 - 2.2e-13 49.0 0.0 0.0036 17.7 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EPE31566.1 - 1.4e-11 44.4 0.0 3e-08 33.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) bZIP_1 PF00170.21 EPE31566.1 - 0.032 14.3 4.9 0.051 13.7 4.9 1.3 1 0 0 1 1 1 0 bZIP transcription factor Tannase PF07519.11 EPE31567.1 - 2.4e-76 257.5 0.8 2.2e-45 155.4 0.0 2.1 1 1 1 2 2 2 2 Tannase and feruloyl esterase FA_hydroxylase PF04116.13 EPE31567.1 - 1.6e-15 57.6 4.6 2.8e-15 56.8 4.6 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily DUF4190 PF13828.6 EPE31567.1 - 0.079 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) Abhydrolase_1 PF00561.20 EPE31568.1 - 2.5e-09 37.2 0.0 5.7e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE31568.1 - 3.1e-07 31.2 3.6 4.7e-06 27.4 3.6 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE31568.1 - 9e-05 21.8 0.1 0.0024 17.2 0.0 2.6 3 0 0 3 3 3 1 Serine aminopeptidase, S33 PAP2 PF01569.21 EPE31569.1 - 3e-25 88.6 0.4 4.9e-24 84.6 0.0 2.5 2 1 0 2 2 2 1 PAP2 superfamily Sulf_transp PF04143.14 EPE31569.1 - 0.033 13.7 0.3 0.1 12.1 0.2 1.8 2 0 0 2 2 2 0 Sulphur transport Aldo_ket_red PF00248.21 EPE31570.1 - 2e-50 171.7 0.0 3.1e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1848 PF08902.11 EPE31570.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) SO_alpha_A3 PF17806.1 EPE31570.1 - 0.16 12.3 0.3 0.55 10.6 0.0 2.0 2 0 0 2 2 2 0 Sarcosine oxidase A3 domain Polysacc_deac_1 PF01522.21 EPE31571.1 - 7.9e-26 90.4 0.0 1.2e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EPE31571.1 - 7e-13 48.8 37.7 2.5e-06 27.8 17.0 2.8 2 0 0 2 2 2 2 Chitin recognition protein CK_II_beta PF01214.18 EPE31572.1 - 6.5e-75 250.9 0.5 9.5e-75 250.4 0.5 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HMG_box PF00505.19 EPE31573.1 - 4.3e-07 30.3 5.3 0.00038 20.8 0.9 3.1 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EPE31573.1 - 7.4e-07 29.7 10.4 1.1e-05 25.9 0.1 3.0 3 0 0 3 3 3 2 HMG-box domain DAG_kinase_N PF14513.6 EPE31573.1 - 3.5 7.8 5.5 2.4 8.4 3.4 1.7 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DEAD PF00270.29 EPE31574.1 - 4.4e-50 169.9 0.0 5e-49 166.4 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE31574.1 - 8.7e-27 93.7 0.0 3.3e-26 91.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE31574.1 - 0.016 15.2 0.0 0.052 13.6 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit eIF-5a PF01287.20 EPE31574.1 - 0.096 12.8 0.5 0.31 11.2 0.5 1.9 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold zf-C2H2 PF00096.26 EPE31576.1 - 7.1e-15 54.5 65.8 0.00012 22.4 2.1 10.1 10 1 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE31576.1 - 1.2e-09 38.1 67.0 0.0014 19.3 1.4 10.2 11 0 0 11 11 11 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPE31576.1 - 4e-07 30.2 9.4 2.4e-05 24.5 0.4 7.3 8 1 0 8 8 8 5 Zinc-finger double domain Ribosomal_L29 PF00831.23 EPE31577.1 - 9.1e-16 57.6 0.3 9.1e-16 57.6 0.3 2.3 2 1 1 3 3 3 1 Ribosomal L29 protein V-SNARE_C PF12352.8 EPE31578.1 - 1.4e-13 50.9 0.2 1.4e-13 50.9 0.2 3.4 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus MPS2 PF17060.5 EPE31578.1 - 0.01 15.2 0.4 0.01 15.1 0.4 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 PA28_beta PF02252.18 EPE31578.1 - 0.038 13.7 0.3 0.1 12.3 0.4 1.6 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit Syntaxin-6_N PF09177.11 EPE31578.1 - 0.083 13.5 6.3 0.16 12.5 4.9 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Not3 PF04065.15 EPE31578.1 - 0.13 11.7 5.8 0.75 9.2 4.0 2.0 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component BBS1 PF14779.6 EPE31578.1 - 0.21 11.0 0.6 0.31 10.4 0.6 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Snapin_Pallidin PF14712.6 EPE31578.1 - 0.86 10.1 9.4 2.4 8.6 9.1 1.9 2 0 0 2 2 2 0 Snapin/Pallidin APG6_N PF17675.1 EPE31578.1 - 1.1 9.8 14.0 2.7 8.5 13.6 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region CENP-H PF05837.12 EPE31578.1 - 1.8 9.0 10.6 0.47 10.9 7.2 1.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Atg14 PF10186.9 EPE31578.1 - 1.9 7.5 11.1 1.9 7.5 10.4 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Flagellin_N PF00669.20 EPE31578.1 - 8 6.6 10.9 0.39 10.8 3.4 2.3 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region FapA PF03961.13 EPE31578.1 - 9.1 4.8 6.0 10 4.6 4.4 1.7 1 1 2 3 3 3 0 Flagellar Assembly Protein A ATP-synt_10 PF05176.14 EPE31579.1 - 5.2e-81 271.7 0.0 7e-81 271.2 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein DUF4849 PF16141.5 EPE31579.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative glycoside hydrolase Family 18, chitinase_18 2-oxoacid_dh PF00198.23 EPE31580.1 - 1.8e-72 243.6 0.3 3.3e-72 242.7 0.1 1.5 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EPE31580.1 - 1.2e-17 63.5 0.0 2.3e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EPE31580.1 - 3.1e-13 49.8 0.8 1.4e-12 47.7 0.1 2.5 3 0 0 3 3 3 1 e3 binding domain HlyD_D23 PF16576.5 EPE31580.1 - 0.0056 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 EPE31580.1 - 0.014 15.2 0.1 0.034 14.0 0.1 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like SKI PF01202.22 EPE31581.1 - 2.5e-11 43.9 0.0 3.2e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.6 EPE31581.1 - 3.3e-08 34.0 0.0 6.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EPE31581.1 - 5.7e-08 33.0 0.0 8.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EPE31581.1 - 2.8e-07 31.1 0.0 1e-06 29.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 EPE31581.1 - 1.6e-05 24.9 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 EPE31581.1 - 1.9e-05 24.5 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Cytidylate kinase Zeta_toxin PF06414.12 EPE31581.1 - 0.00015 21.1 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 EPE31581.1 - 0.00052 20.4 0.0 0.00078 19.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 EPE31581.1 - 0.0006 19.7 0.0 0.00079 19.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.29 EPE31581.1 - 0.0014 19.1 0.1 0.0031 17.9 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EPE31581.1 - 0.0022 18.5 0.0 0.0033 17.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 EPE31581.1 - 0.0038 17.6 0.0 0.0067 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 EPE31581.1 - 0.0073 16.2 0.5 0.3 11.0 0.1 2.3 2 1 0 2 2 2 1 NTPase AAA_22 PF13401.6 EPE31581.1 - 0.011 16.0 0.0 0.018 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EPE31581.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 EPE31581.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EPE31581.1 - 0.016 14.9 0.2 0.031 14.0 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 EPE31581.1 - 0.017 15.4 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 EPE31581.1 - 0.018 14.7 0.0 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_11 PF13086.6 EPE31581.1 - 0.027 14.3 0.0 0.12 12.1 0.0 1.8 1 1 1 2 2 2 0 AAA domain PRK PF00485.18 EPE31581.1 - 0.027 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ATPase_2 PF01637.18 EPE31581.1 - 0.051 13.5 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea IPT PF01745.16 EPE31581.1 - 0.061 12.7 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase AAA_30 PF13604.6 EPE31581.1 - 0.066 12.9 1.2 0.08 12.7 0.2 1.7 2 1 0 2 2 2 0 AAA domain DNA_pol3_delta2 PF13177.6 EPE31581.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 EPE31581.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EPE31581.1 - 0.08 13.0 0.0 0.17 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EPE31581.1 - 0.088 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EPE31581.1 - 0.089 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RuvB_N PF05496.12 EPE31581.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain dNK PF01712.19 EPE31581.1 - 0.12 12.2 0.1 2.1 8.1 0.0 2.2 1 1 0 2 2 2 0 Deoxynucleoside kinase AAA_23 PF13476.6 EPE31581.1 - 0.13 12.8 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain HpcH_HpaI PF03328.14 EPE31582.1 - 1.6e-34 119.0 0.0 2e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family GFO_IDH_MocA PF01408.22 EPE31582.1 - 0.034 15.0 0.1 8.1 7.3 0.0 2.6 2 1 1 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold Coiled-coil_56 PF09813.9 EPE31585.1 - 3.6e-05 23.7 0.0 3.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.8 EPE31586.1 - 6.8e-57 192.7 6.1 1.8e-41 142.3 0.4 3.0 2 1 1 3 3 3 2 Domain of unknown function (DUF3453) SHE3 PF17078.5 EPE31587.1 - 2.3 7.9 21.0 0.093 12.4 8.2 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 ISG65-75 PF11727.8 EPE31587.1 - 6 6.0 22.3 0.075 12.3 4.1 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein Agenet PF05641.12 EPE31588.1 - 0.11 13.0 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Agenet domain Pectate_lyase_3 PF12708.7 EPE31590.1 - 2.6e-100 334.7 14.7 1.2e-84 283.5 4.9 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EPE31590.1 - 1.3e-05 24.8 2.9 0.07 12.8 0.2 2.5 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase PNGaseA PF12222.8 EPE31591.1 - 6.7e-139 463.5 2.2 9.6e-139 463.0 2.2 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A THF_DHG_CYH PF00763.23 EPE31593.1 - 1.5e-23 83.3 0.0 2.5e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EPE31593.1 - 2e-14 53.2 0.0 1.5e-12 47.1 0.0 2.4 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Arabinose_Isome PF02610.15 EPE31593.1 - 0.028 13.6 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 L-arabinose isomerase CdiI_N PF18228.1 EPE31593.1 - 0.071 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 CdiI N-terminal domain AAA_31 PF13614.6 EPE31593.1 - 0.072 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DpaA_N PF16924.5 EPE31593.1 - 0.13 12.4 0.0 0.47 10.6 0.0 1.9 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain MMS19_N PF14500.6 EPE31594.1 - 3.8e-44 151.2 0.4 5.5e-42 144.2 0.0 3.8 5 0 0 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 EPE31594.1 - 1.9e-28 99.7 0.3 5.4e-28 98.3 0.0 1.8 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT PF02985.22 EPE31594.1 - 0.0053 16.9 3.8 6.1 7.4 0.2 4.9 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 EPE31594.1 - 0.014 15.5 2.6 7.3 6.6 0.0 4.4 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.6 EPE31594.1 - 0.13 11.9 0.8 0.54 9.9 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) EMC3_TMCO1 PF01956.16 EPE31595.1 - 2.2e-52 177.2 2.9 3e-52 176.8 2.9 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like SPC25 PF06703.11 EPE31596.1 - 9.9e-53 178.2 5.2 1.3e-52 177.8 5.2 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Brix PF04427.18 EPE31597.1 - 9.8e-43 146.5 0.1 1.5e-42 145.9 0.1 1.2 1 0 0 1 1 1 1 Brix domain Gar1 PF04410.14 EPE31597.1 - 0.17 11.6 1.9 0.33 10.7 1.9 1.5 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region Spo12 PF05032.12 EPE31597.1 - 3.5 7.6 6.1 0.55 10.2 0.6 2.4 2 0 0 2 2 2 0 Spo12 family Tim17 PF02466.19 EPE31598.1 - 3.4e-11 43.5 1.0 5.7e-11 42.8 1.0 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Prenylcys_lyase PF07156.14 EPE31600.1 - 6.8e-17 61.6 0.0 1.1e-15 57.6 0.0 2.0 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_9 PF13454.6 EPE31600.1 - 1.3e-07 31.7 0.2 2e-05 24.6 0.0 2.4 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EPE31600.1 - 4.9e-06 26.7 0.0 2.7e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE31600.1 - 1.5e-05 24.8 0.1 9.3e-05 22.2 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE31600.1 - 0.075 12.2 0.1 0.42 9.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase eIF-3_zeta PF05091.12 EPE31601.1 - 1.6e-215 717.0 0.0 1.9e-215 716.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 EPE31601.1 - 0.0039 16.9 0.1 0.01 15.5 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF569) bZIP_1 PF00170.21 EPE31602.1 - 1.5e-06 28.2 10.2 3e-06 27.2 10.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPE31602.1 - 0.0045 17.0 3.5 0.0045 17.0 3.5 2.2 2 0 0 2 2 2 1 Basic region leucine zipper DUF5082 PF16888.5 EPE31602.1 - 0.014 15.7 0.7 0.025 14.8 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) bZIP_Maf PF03131.17 EPE31602.1 - 1.3 9.5 8.0 3 8.4 8.0 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Acyltransferase PF01553.21 EPE31603.1 - 5.5e-15 55.2 0.0 7.8e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EPE31603.1 - 5.1e-09 36.1 0.2 2.9e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 Acyltransferase C-terminus Asn_synthase PF00733.21 EPE31605.1 - 5.3e-17 62.5 0.0 3.1e-06 27.1 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 EPE31605.1 - 0.00031 20.6 0.0 0.0011 18.9 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain VPS9 PF02204.18 EPE31606.1 - 9e-29 99.8 0.0 1.6e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EPE31606.1 - 1.4e-13 50.9 0.1 3.2e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 EPE31606.1 - 8.3e-10 38.2 0.1 1.4e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 CUE domain CRC_subunit PF08624.10 EPE31609.1 - 4e-53 179.5 0.2 5.6e-53 179.0 0.2 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Amidoligase_2 PF12224.8 EPE31611.1 - 1.6e-20 73.8 0.0 4.7e-20 72.3 0.0 1.8 1 1 0 1 1 1 1 Putative amidoligase enzyme ApoO PF09769.9 EPE31611.1 - 0.042 13.8 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein O Lipase_GDSL_2 PF13472.6 EPE31613.1 - 1.4e-05 25.6 3.7 2.6e-05 24.7 3.7 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE31613.1 - 0.00075 19.5 0.0 0.0015 18.6 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase VIT1 PF01988.19 EPE31614.1 - 2.7e-60 203.9 5.0 3.2e-60 203.7 5.0 1.0 1 0 0 1 1 1 1 VIT family Glyco_hydro_88 PF07470.13 EPE31615.1 - 4e-18 65.6 0.1 5.6e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_114 PF03537.13 EPE31616.1 - 3.7e-83 278.4 0.2 4.9e-83 278.0 0.2 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Caprin-1_C PF12287.8 EPE31616.1 - 1.1 9.3 6.7 1.9 8.6 6.7 1.3 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term DUF4592 PF15262.6 EPE31616.1 - 7.7 7.2 10.2 15 6.2 10.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) APH PF01636.23 EPE31617.1 - 6.9e-08 32.7 0.0 1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE31617.1 - 0.00052 19.7 0.0 0.00085 19.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase MFS_1 PF07690.16 EPE31618.1 - 2.6e-30 105.6 79.3 7.7e-26 90.8 46.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPE31618.1 - 0.0002 20.0 6.4 0.00029 19.4 6.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Kelch_1 PF01344.25 EPE31618.1 - 0.011 15.3 0.7 0.026 14.1 0.7 1.6 1 0 0 1 1 1 0 Kelch motif Cu_amine_oxid PF01179.20 EPE31619.1 - 4.2e-163 543.0 0.0 5e-163 542.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EPE31619.1 - 4.4e-22 78.4 0.1 1e-21 77.2 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EPE31619.1 - 4.3e-12 46.1 0.0 8.1e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RdgC PF04381.12 EPE31619.1 - 0.029 13.7 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative exonuclease, RdgC Alanine_zipper PF11839.8 EPE31621.1 - 0.87 10.0 5.2 1.4 9.3 5.2 1.3 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein SMN PF06003.12 EPE31621.1 - 2.4 7.3 4.6 6.1 6.0 4.6 1.6 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Tfb2 PF03849.14 EPE31622.1 - 3.1e-138 460.6 0.1 4.9e-138 459.9 0.0 1.3 2 0 0 2 2 2 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EPE31622.1 - 1.6e-20 73.3 1.1 2.8e-20 72.5 1.1 1.4 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EPE31622.1 - 6.1e-06 26.4 0.1 1.6e-05 25.0 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain LIP1 PF15904.5 EPE31622.1 - 0.057 13.8 1.2 0.27 11.6 0.1 2.6 3 0 0 3 3 3 0 LKB1 serine/threonine kinase interacting protein 1 4HBT PF03061.22 EPE31623.1 - 1.5e-11 44.5 0.1 2.3e-11 43.9 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EPE31623.1 - 0.018 15.2 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Sugar_tr PF00083.24 EPE31624.1 - 3.1e-112 375.7 19.7 3.7e-112 375.5 19.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE31624.1 - 1.1e-22 80.5 41.8 8.9e-22 77.5 23.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3147 PF11345.8 EPE31624.1 - 0.31 11.4 7.9 18 5.8 0.2 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3147) LXG PF04740.12 EPE31626.1 - 0.096 12.4 0.2 0.41 10.3 0.0 2.1 2 1 1 3 3 3 0 LXG domain of WXG superfamily Arm PF00514.23 EPE31627.1 - 1e-06 28.6 3.2 1.4 9.1 0.0 5.5 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat KAP PF05804.12 EPE31627.1 - 0.00014 20.2 0.1 0.014 13.6 0.0 2.2 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) Flavin_Reduct PF01613.18 EPE31628.1 - 0.035 14.2 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 Flavin reductase like domain Band_7 PF01145.25 EPE31628.1 - 0.32 11.0 2.6 0.67 9.9 2.6 1.5 1 0 0 1 1 1 0 SPFH domain / Band 7 family MPS2 PF17060.5 EPE31628.1 - 0.32 10.2 5.9 0.49 9.6 5.9 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 YabA PF06156.13 EPE31628.1 - 2.1 9.0 4.8 10 6.8 0.2 2.7 2 1 0 2 2 2 0 Initiation control protein YabA LRR_8 PF13855.6 EPE31629.1 - 4.7e-32 109.5 46.7 4e-07 29.7 5.9 8.8 6 3 4 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 EPE31629.1 - 4.1e-28 97.0 57.0 6.3e-05 23.3 1.3 10.0 9 1 0 10 10 10 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EPE31629.1 - 0.0076 16.6 44.1 18 6.4 0.1 13.5 11 2 0 11 11 11 1 Leucine Rich Repeat LRR_9 PF14580.6 EPE31629.1 - 0.045 13.3 16.5 0.44 10.0 1.3 4.6 3 2 2 5 5 5 0 Leucine-rich repeat LRR_6 PF13516.6 EPE31629.1 - 0.26 11.5 49.2 0.46 10.7 0.2 11.8 13 0 0 13 13 13 0 Leucine Rich repeat Lactamase_B PF00753.27 EPE31631.1 - 2.4e-07 31.0 0.0 6.5e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EPE31631.1 - 0.018 14.5 0.0 0.039 13.5 0.0 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Pribosyltran PF00156.27 EPE31632.1 - 4.9e-07 29.4 0.0 9.4e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain 2-Hacid_dh_C PF02826.19 EPE31633.1 - 4.6e-45 153.2 0.1 1.5e-30 105.9 0.0 2.9 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EPE31633.1 - 0.001 18.4 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EPE31633.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EPE31633.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 EPE31633.1 - 0.16 11.6 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Methyltransf_16 PF10294.9 EPE31635.1 - 3.7e-45 153.8 0.0 5.3e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EPE31635.1 - 0.038 13.5 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain WW PF00397.26 EPE31636.1 - 0.0045 17.0 7.0 0.017 15.2 0.0 3.8 4 0 0 4 4 4 1 WW domain EF-hand_4 PF12763.7 EPE31636.1 - 0.0055 16.6 0.2 0.77 9.7 0.0 2.9 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand UvdE PF03851.14 EPE31637.1 - 2e-110 368.4 0.0 2.7e-110 368.0 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE KRAB PF01352.27 EPE31638.1 - 0.42 10.3 4.3 1.5 8.6 3.1 2.3 2 0 0 2 2 2 0 KRAB box DUF4159 PF13709.6 EPE31640.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) CMD PF02627.20 EPE31644.1 - 0.00017 21.6 0.6 0.00031 20.7 0.0 1.7 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family PAP_assoc PF03828.19 EPE31645.1 - 2.9e-11 43.4 0.1 6.6e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EPE31645.1 - 8.5e-10 38.8 0.0 2.1e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.6 EPE31645.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) EF1G PF00647.19 EPE31646.1 - 5.6e-46 155.0 0.1 9.3e-46 154.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EPE31646.1 - 1.4e-13 50.9 1.7 1.5e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EPE31646.1 - 2.4e-12 47.0 0.1 2.2e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPE31646.1 - 4.9e-08 32.9 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EPE31646.1 - 1e-06 29.1 0.1 3e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EPE31646.1 - 3e-05 24.1 0.0 0.00014 22.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EPE31646.1 - 0.068 13.5 0.0 0.24 11.7 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain NIF PF03031.18 EPE31647.1 - 1.9e-18 66.7 0.0 2.6e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ndc1_Nup PF09531.10 EPE31647.1 - 0.25 10.0 3.3 0.28 9.8 3.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Herpes_DNAp_acc PF04929.12 EPE31647.1 - 8.5 5.2 11.4 13 4.7 11.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RRP36 PF06102.12 EPE31648.1 - 4.7e-57 192.6 30.6 4.7e-57 192.6 30.6 1.8 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 DUF1824 PF08854.10 EPE31648.1 - 0.81 9.6 2.7 3.9 7.4 2.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1824) ABC1 PF03109.16 EPE31649.1 - 2.8e-34 117.8 0.0 1.1e-33 115.9 0.0 2.1 2 0 0 2 2 2 1 ABC1 family DUF5327 PF17261.2 EPE31649.1 - 3 8.6 0.0 3 8.6 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Es2 PF09751.9 EPE31650.1 - 2.6e-118 396.5 9.4 3.3e-118 396.2 9.4 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 DUF1918 PF08940.11 EPE31651.1 - 0.0021 17.6 0.8 4.4 7.0 0.1 4.1 3 0 0 3 3 3 2 Domain of unknown function (DUF1918) Whi5 PF08528.11 EPE31652.1 - 2.9e-09 36.3 0.1 5.4e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 Whi5 like Metallopep PF12044.8 EPE31653.1 - 1e-171 571.3 0.0 1.3e-171 570.9 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 EPE31653.1 - 0.00024 21.3 1.6 0.00028 21.1 0.2 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EPE31653.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EPE31653.1 - 0.36 11.3 1.8 0.85 10.2 1.8 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CDP-OH_P_transf PF01066.21 EPE31654.1 - 1.7e-13 51.1 0.1 4.3e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Gar1 PF04410.14 EPE31655.1 - 2.8e-38 131.1 0.0 3.2e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.25 EPE31656.1 - 6.9e-32 110.9 0.0 6.6e-30 104.4 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EPE31656.1 - 1.6e-16 60.2 0.2 3.2e-16 59.2 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EPE31656.1 - 3.8e-13 49.3 0.0 7.9e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EPE31656.1 - 7e-11 42.0 0.0 1.4e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain PH PF00169.29 EPE31657.1 - 7.3e-06 26.4 0.1 1.5e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 PH domain WEMBL PF05701.11 EPE31657.1 - 1.6 7.3 10.3 0.01 14.6 1.8 1.5 2 0 0 2 2 2 0 Weak chloroplast movement under blue light DUF2013 PF09431.10 EPE31658.1 - 1.7e-51 174.0 2.6 3e-51 173.2 2.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Pox_Rap94 PF03294.14 EPE31658.1 - 0.12 10.4 0.1 0.2 9.7 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 DnaJ PF00226.31 EPE31659.1 - 2.4e-19 69.2 0.7 2.4e-19 69.2 0.7 3.0 3 0 0 3 3 3 1 DnaJ domain TPR_9 PF13371.6 EPE31659.1 - 2.3e-15 56.5 0.7 0.0003 20.9 0.0 4.9 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EPE31659.1 - 4.2e-13 48.3 13.1 0.0024 17.8 0.0 8.2 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 EPE31659.1 - 2e-12 46.3 12.6 6.6e-05 22.6 0.0 7.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPE31659.1 - 4.1e-09 35.9 3.8 0.0032 17.6 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EPE31659.1 - 4.9e-09 36.3 5.6 0.31 12.0 0.0 6.0 3 1 3 6 6 6 3 Tetratricopeptide repeat PknG_TPR PF16918.5 EPE31659.1 - 6.9e-09 34.9 0.4 0.00052 18.8 0.1 3.2 3 0 0 3 3 3 2 Protein kinase G tetratricopeptide repeat TPR_19 PF14559.6 EPE31659.1 - 5.9e-08 33.1 9.2 0.015 15.8 0.2 4.8 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EPE31659.1 - 6.3e-07 29.0 4.2 0.00014 21.5 0.1 4.5 2 1 2 4 4 4 1 TPR repeat TPR_7 PF13176.6 EPE31659.1 - 1.2e-06 28.1 4.8 0.077 13.1 0.1 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EPE31659.1 - 1.7e-06 28.0 3.5 0.001 19.3 0.1 4.8 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EPE31659.1 - 1.4e-05 25.4 12.3 3.8 8.4 0.0 7.6 7 2 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE31659.1 - 6.9e-05 23.0 8.5 0.45 10.8 0.9 5.3 4 2 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EPE31659.1 - 0.00029 21.4 9.7 0.049 14.3 0.0 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPE31659.1 - 0.0015 18.8 15.1 0.098 13.0 0.1 6.7 5 3 1 6 6 6 1 Tetratricopeptide repeat SesA PF17107.5 EPE31659.1 - 0.044 14.0 1.1 6.2 7.0 0.1 2.6 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Sharpin_PH PF16764.5 EPE31659.1 - 0.052 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Sharpin PH domain DUF5345 PF17280.2 EPE31659.1 - 0.15 12.1 0.2 0.47 10.5 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5345) YfiO PF13525.6 EPE31659.1 - 0.17 11.6 3.8 0.42 10.3 0.2 3.0 3 1 0 3 3 3 0 Outer membrane lipoprotein TPR_10 PF13374.6 EPE31659.1 - 0.25 11.3 4.7 14 5.7 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EPE31659.1 - 0.31 11.5 7.5 7.1 7.1 0.4 3.8 3 1 1 4 4 4 0 Alkyl sulfatase dimerisation TPR_4 PF07721.14 EPE31659.1 - 3.7 8.5 6.1 1.5e+02 3.4 2.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat YfdX PF10938.8 EPE31659.1 - 8.1 6.4 15.1 11 5.9 0.3 4.4 5 1 1 6 6 6 0 YfdX protein Vac14_Fig4_bd PF11916.8 EPE31661.1 - 1.8e-81 272.1 8.1 1.8e-81 272.1 8.1 1.6 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EPE31661.1 - 1.3e-45 153.9 0.0 2.1e-42 143.7 0.0 3.8 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EPE31661.1 - 6.8e-08 32.9 4.0 0.013 16.0 0.1 5.6 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.22 EPE31661.1 - 3e-07 30.1 0.3 0.002 18.2 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 EPE31661.1 - 7.7e-06 26.0 0.1 0.01 15.9 0.2 3.4 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EPE31661.1 - 0.00058 20.2 2.0 0.37 11.2 0.0 4.7 5 0 0 5 5 5 1 HEAT repeats Arm PF00514.23 EPE31661.1 - 0.011 15.7 0.0 17 5.7 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat SLATT_5 PF18160.1 EPE31662.1 - 0.0022 17.3 0.0 0.007 15.7 0.0 1.7 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 DUF1465 PF07323.12 EPE31663.1 - 0.13 12.1 1.6 0.3 10.9 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Pet191_N PF10203.9 EPE31664.1 - 0.025 14.9 2.0 0.19 12.0 2.3 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.16 EPE31664.1 - 0.029 14.6 0.7 0.046 13.9 0.7 1.4 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.13 EPE31664.1 - 0.037 14.4 2.8 0.82 10.1 0.3 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 EPE31664.1 - 0.047 13.8 0.1 0.11 12.7 0.1 1.7 1 1 0 1 1 1 0 CHCH domain UPF0203 PF05254.12 EPE31664.1 - 0.28 11.4 2.2 12 6.3 0.1 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) 40S_S4_C PF16121.5 EPE31665.1 - 0.045 13.4 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus FA_desaturase PF00487.24 EPE31667.1 - 9.4e-28 97.7 27.2 1.3e-27 97.3 27.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EPE31667.1 - 1.4e-10 41.1 0.0 3.1e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pyr_redox_2 PF07992.14 EPE31669.1 - 4.7e-68 229.6 7.7 4.7e-68 229.6 7.7 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EPE31669.1 - 1.9e-40 137.5 0.4 6.1e-40 135.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EPE31669.1 - 5.8e-22 78.1 10.3 5.3e-19 68.6 1.2 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE31669.1 - 1.4e-10 41.3 2.8 1.5e-06 28.4 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EPE31669.1 - 1.5e-09 37.8 0.8 1.5e-09 37.8 0.8 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 EPE31669.1 - 7.4e-09 35.2 14.3 9.5e-08 31.5 5.3 3.0 2 2 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EPE31669.1 - 8.5e-08 31.8 2.0 0.00033 20.0 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE31669.1 - 1.2e-06 27.9 2.3 1.2e-06 27.9 2.3 2.6 2 1 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EPE31669.1 - 3.5e-06 26.5 8.5 0.0085 15.4 0.5 3.1 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EPE31669.1 - 3.8e-06 25.9 15.4 0.00013 20.8 1.8 4.1 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.17 EPE31669.1 - 3.4e-05 23.2 3.6 0.00039 19.7 0.1 2.4 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 EPE31669.1 - 0.00021 20.5 1.2 0.91 8.6 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EPE31669.1 - 0.00061 19.5 15.7 0.0022 17.6 0.6 4.0 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EPE31669.1 - 0.0097 15.2 10.9 0.13 11.5 1.0 3.3 3 1 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.12 EPE31669.1 - 0.014 14.4 4.4 0.025 13.6 0.2 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 EPE31669.1 - 0.047 14.1 3.6 1.8 9.0 0.1 3.0 2 1 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EPE31669.1 - 0.38 10.6 5.4 0.81 9.5 1.0 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EPE31669.1 - 5.3 6.6 6.8 7.2 6.1 0.6 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HLH PF00010.26 EPE31670.1 - 1.5e-11 44.1 3.3 1.1e-10 41.3 3.3 2.2 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4554 PF15091.6 EPE31670.1 - 0.21 10.4 0.5 0.34 9.8 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) NPR3 PF03666.13 EPE31671.1 - 2.2e-131 438.9 2.3 2e-113 379.7 0.4 2.6 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 Dala_Dala_lig_N PF01820.21 EPE31671.1 - 0.0026 18.2 0.1 0.0061 17.0 0.1 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus Fam20C PF06702.12 EPE31671.1 - 0.052 13.4 0.1 0.093 12.5 0.1 1.3 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 DEAD PF00270.29 EPE31673.1 - 4.2e-41 140.6 1.3 6.9e-41 139.9 1.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE31673.1 - 2.1e-30 105.3 0.1 3e-29 101.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE31673.1 - 1.2e-07 31.8 0.0 2.8e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 EPE31673.1 - 0.029 12.7 0.3 0.038 12.3 0.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1682 PF07946.14 EPE31674.1 - 3.9e-117 391.1 0.1 4.5e-117 390.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Haspin_kinase PF12330.8 EPE31675.1 - 2.7e-38 131.9 0.0 3.8e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Nucleoside_tran PF01733.18 EPE31676.1 - 4.7e-41 141.2 15.3 6.6e-39 134.1 15.3 2.6 1 1 0 1 1 1 1 Nucleoside transporter HMG_box PF00505.19 EPE31679.1 - 8.6e-17 61.3 0.9 2.3e-16 60.0 0.9 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EPE31679.1 - 2.9e-13 50.2 0.7 8e-13 48.8 0.7 1.8 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.30 EPE31679.1 - 1.1e-08 35.3 0.0 2.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EPE31679.1 - 4e-06 26.8 0.0 9.5e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RIO1 PF01163.22 EPE31680.1 - 9e-70 234.1 1.2 1.2e-69 233.7 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 EPE31680.1 - 0.00065 19.1 0.2 0.46 9.8 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPE31680.1 - 0.071 13.0 0.2 4.5 7.1 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EPE31680.1 - 0.18 10.5 3.1 0.097 11.4 0.2 1.9 2 0 0 2 2 2 0 Fungal protein kinase CR6_interact PF10147.9 EPE31680.1 - 1.5 8.5 12.6 3.4 7.3 12.6 1.5 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 ApoL PF05461.11 EPE31682.1 - 0.011 15.0 0.4 0.023 14.0 0.4 1.4 1 0 0 1 1 1 0 Apolipoprotein L Rsa3 PF14615.6 EPE31682.1 - 0.2 11.3 1.2 7.6 6.2 0.0 2.6 2 0 0 2 2 2 0 Ribosome-assembly protein 3 DHR10 PF18595.1 EPE31682.1 - 0.75 9.9 7.2 0.17 11.9 0.9 2.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Fez1 PF06818.15 EPE31682.1 - 2.6 8.5 7.3 1.7 9.1 3.5 2.1 2 0 0 2 2 2 0 Fez1 CLZ PF16526.5 EPE31684.1 - 0.00068 19.9 8.1 0.015 15.7 1.0 3.8 4 0 0 4 4 4 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1192 PF06698.11 EPE31684.1 - 0.082 13.0 5.7 0.2 11.7 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) KLRAQ PF10205.9 EPE31684.1 - 0.44 10.8 7.0 8.2 6.7 1.4 3.1 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein ZapB PF06005.12 EPE31684.1 - 0.97 9.9 16.1 1.1 9.8 1.6 3.0 2 0 0 2 2 2 0 Cell division protein ZapB Cep57_CLD PF14073.6 EPE31684.1 - 1.1 9.2 9.2 0.27 11.3 2.0 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 TMF_DNA_bd PF12329.8 EPE31684.1 - 1.2 9.2 8.6 2.2 8.3 1.2 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 EPE31684.1 - 2.4 8.2 13.7 8.9 6.3 6.5 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PCRF PF03462.18 EPE31684.1 - 3 7.7 4.8 12 5.7 0.7 2.4 2 0 0 2 2 2 0 PCRF domain DUF4472 PF14739.6 EPE31684.1 - 4.6 8.0 10.8 1 10.1 1.7 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF4472) APG6_N PF17675.1 EPE31684.1 - 7.4 7.1 18.6 8.8 6.9 3.4 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region SYF2 PF08231.12 EPE31689.1 - 2.2e-57 193.9 13.0 2.2e-57 193.9 13.0 2.0 2 0 0 2 2 2 1 SYF2 splicing factor ARD PF03079.14 EPE31689.1 - 1.3 9.2 7.9 0.37 11.0 0.1 2.8 1 1 2 3 3 3 0 ARD/ARD' family NAD_binding_10 PF13460.6 EPE31690.1 - 5.8e-08 32.8 0.0 4.3e-07 30.0 0.0 2.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE31690.1 - 1.4e-06 27.9 0.0 4e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE31690.1 - 0.0018 17.4 0.0 0.0039 16.3 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EPE31690.1 - 0.0021 17.2 0.0 0.019 14.1 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 EPE31690.1 - 0.0057 15.8 0.0 0.041 13.0 0.0 2.2 2 1 0 2 2 2 1 RmlD substrate binding domain YEATS PF03366.16 EPE31691.1 - 1.3e-32 111.6 0.4 1.9e-32 111.1 0.4 1.2 1 0 0 1 1 1 1 YEATS family Ins_P5_2-kin PF06090.12 EPE31692.1 - 1.6e-40 139.6 0.0 7.6e-40 137.3 0.0 1.9 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Disintegrin PF00200.23 EPE31694.1 - 0.2 12.5 15.1 0.29 12.0 15.1 1.2 1 0 0 1 1 1 0 Disintegrin LtrA PF06772.11 EPE31695.1 - 1e-24 87.4 24.1 1e-24 87.4 24.1 2.1 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) MWFE PF15879.5 EPE31695.1 - 0.06 13.5 0.1 0.38 11.0 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit F-box-like PF12937.7 EPE31696.1 - 0.0013 18.6 0.3 0.0033 17.3 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EPE31696.1 - 0.065 13.1 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 F-box DUF2070 PF09843.9 EPE31697.1 - 9.9 4.3 17.3 8.8 4.5 16.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) SAP130_C PF16014.5 EPE31698.1 - 0.021 14.0 0.5 0.034 13.2 0.5 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Hen1_L PF12623.7 EPE31698.1 - 0.056 12.5 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 SNARE PF05739.19 EPE31701.1 - 2.5e-15 56.2 0.5 4.7e-15 55.3 0.5 1.5 1 0 0 1 1 1 1 SNARE domain Nab1 PF04902.12 EPE31701.1 - 0.013 15.9 0.3 0.029 14.8 0.3 1.6 1 1 0 1 1 1 0 Conserved region in Nab1 Syntaxin PF00804.25 EPE31701.1 - 0.015 14.9 9.3 0.17 11.6 9.3 2.1 1 1 0 1 1 1 0 Syntaxin MCPsignal PF00015.21 EPE31701.1 - 0.7 9.7 7.3 0.52 10.1 1.2 2.4 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DNA_repr_REX1B PF14966.6 EPE31701.1 - 2.2 9.0 5.6 1.2 9.9 0.1 2.9 3 1 1 4 4 4 0 DNA repair REX1-B EF-hand_1 PF00036.32 EPE31702.1 - 7.1e-41 134.7 12.9 1.3e-09 36.9 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EPE31702.1 - 1.1e-35 121.8 5.8 7.6e-19 67.9 2.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EPE31702.1 - 4.2e-34 116.2 12.0 4.2e-15 55.3 0.6 4.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EPE31702.1 - 4.4e-30 101.0 8.0 3.1e-09 36.0 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EPE31702.1 - 3.8e-25 86.2 10.6 4.1e-06 26.0 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EPE31702.1 - 4.5e-16 58.9 0.4 4.5e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EPE31702.1 - 9.8e-09 35.1 1.7 0.0015 18.5 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EPE31702.1 - 1.2e-08 35.3 0.2 0.0036 17.6 0.1 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EPE31702.1 - 2.7e-06 27.3 0.0 0.013 15.5 0.0 3.1 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EPE31702.1 - 1.6e-05 24.9 1.6 4.7e-05 23.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 EPE31702.1 - 0.00023 22.0 0.2 0.0045 17.8 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 EPE31702.1 - 0.00037 20.5 0.3 0.71 9.8 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 EPE31702.1 - 0.0012 18.8 1.1 0.63 10.0 0.0 3.5 1 1 2 3 3 3 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 EPE31702.1 - 0.0013 19.1 0.7 0.93 9.8 0.2 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb4 DUF2267 PF10025.9 EPE31702.1 - 0.0028 17.9 0.0 0.028 14.7 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2267) DUF3349 PF11829.8 EPE31702.1 - 0.0028 18.4 0.4 3.7 8.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF5580 PF17743.1 EPE31702.1 - 0.011 14.3 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 EPE31702.1 - 0.017 15.3 6.8 0.64 10.3 0.9 2.9 1 1 1 2 2 2 0 Dockerin type I domain SurA_N_2 PF13623.6 EPE31702.1 - 0.025 14.4 0.9 0.83 9.5 0.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_14 PF17959.1 EPE31702.1 - 0.034 14.5 0.4 12 6.3 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain DUF4497 PF14924.6 EPE31702.1 - 0.051 14.0 0.0 14 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Poly_export PF02563.16 EPE31702.1 - 0.059 13.6 0.0 0.43 10.8 0.0 2.3 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DED PF01335.21 EPE31702.1 - 0.074 13.4 0.9 3.2 8.1 0.0 2.7 2 1 0 2 2 2 0 Death effector domain RloB PF13707.6 EPE31702.1 - 0.079 13.2 0.8 0.97 9.6 0.8 2.1 1 1 0 1 1 1 0 RloB-like protein MgtE_N PF03448.17 EPE31702.1 - 0.12 13.0 1.5 1.3 9.6 0.0 2.2 1 1 1 2 2 2 0 MgtE intracellular N domain MotA_activ PF09114.10 EPE31702.1 - 0.15 12.2 0.2 2.1 8.5 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain RuvA_C PF07499.13 EPE31702.1 - 0.18 12.3 0.1 14 6.3 0.0 2.9 3 0 0 3 3 3 0 RuvA, C-terminal domain Glyco_hydro_47 PF01532.20 EPE31703.1 - 2e-172 574.2 0.0 2.3e-172 574.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 EPE31703.1 - 0.043 12.3 0.0 6.4 5.1 0.0 2.1 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 NikR_C PF08753.11 EPE31704.1 - 0.0075 16.4 0.2 3 8.1 0.0 3.3 3 1 0 3 3 3 1 NikR C terminal nickel binding domain Shikimate_DH PF01488.20 EPE31704.1 - 0.017 15.2 0.3 0.031 14.3 0.1 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SAC3_GANP PF03399.16 EPE31704.1 - 0.035 13.5 1.0 0.047 13.1 1.0 1.6 1 1 0 1 1 1 0 SAC3/GANP family F-box-like PF12937.7 EPE31705.1 - 5.3e-06 26.2 0.5 2.6e-05 24.0 0.3 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EPE31705.1 - 1.8 9.1 8.7 9.2 6.8 0.2 3.6 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) F-box PF00646.33 EPE31705.1 - 1.8 8.5 7.3 14 5.7 0.4 3.4 3 1 0 3 3 3 0 F-box domain HAD_2 PF13419.6 EPE31706.1 - 9.6e-10 38.8 0.0 1.6e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPE31706.1 - 7.9e-06 26.3 0.0 1e-05 25.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPE31706.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like FAD_binding_1 PF00667.20 EPE31708.1 - 7.4e-45 153.2 0.0 1.1e-44 152.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EPE31708.1 - 6.3e-11 42.9 0.0 1.2e-10 42.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Nitroreductase PF00881.24 EPE31709.1 - 3.1e-14 53.4 0.0 3.7e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family BTB PF00651.31 EPE31710.1 - 0.00062 20.0 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF2841 PF11001.8 EPE31710.1 - 0.025 14.6 0.1 0.039 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2841) BTB PF00651.31 EPE31711.1 - 4e-07 30.3 0.0 8.3e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EPE31712.1 - 2.8e-17 62.9 0.0 2.7e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain DUF3342 PF11822.8 EPE31712.1 - 7.2e-05 22.9 0.3 0.36 11.1 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3342) Glyco_hydro_46 PF01374.18 EPE31712.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 DUF1882 PF08966.11 EPE31712.1 - 1.1 9.6 3.0 31 4.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1882) CXCL17 PF15211.6 EPE31712.1 - 4.6 8.1 10.0 3.2 8.6 0.5 3.4 3 1 1 4 4 4 0 VEGF co-regulated chemokine 1 p450 PF00067.22 EPE31714.1 - 5.9e-44 150.6 0.0 5.3e-37 127.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 EPE31715.1 - 1.3e-39 136.2 0.0 1.4e-39 136.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1769 PF08588.10 EPE31715.1 - 0.065 13.5 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Prenyltrans PF00432.21 EPE31716.1 - 0.0019 17.9 0.4 0.16 11.8 0.0 3.9 3 0 0 3 3 3 1 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EPE31716.1 - 0.02 14.0 0.0 0.4 9.7 0.0 2.8 3 0 0 3 3 3 0 Squalene-hopene cyclase C-terminal domain BTB PF00651.31 EPE31717.1 - 7.1e-11 42.3 0.0 9.8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain DUF3342 PF11822.8 EPE31717.1 - 0.032 14.4 0.0 0.047 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Pkinase PF00069.25 EPE31719.1 - 1.3e-40 139.5 0.0 1.6e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE31719.1 - 2.2e-25 89.4 0.0 3.1e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPE31719.1 - 5.7e-06 25.4 0.0 1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EPE31719.1 - 0.00083 18.8 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA PF00498.26 EPE31719.1 - 0.00093 19.5 0.1 0.0051 17.1 0.0 2.3 3 0 0 3 3 3 1 FHA domain Kinase-like PF14531.6 EPE31719.1 - 0.0028 17.0 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPE31719.1 - 0.16 11.8 1.3 1.1 9.1 1.3 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Shisa PF13908.6 EPE31720.1 - 1.1e-05 25.8 0.3 1.4e-05 25.5 0.3 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator RCR PF12273.8 EPE31720.1 - 2e-05 25.2 3.8 3.3e-05 24.5 3.8 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red EphA2_TM PF14575.6 EPE31720.1 - 4.1e-05 24.4 0.4 0.00018 22.3 0.3 2.0 2 1 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 EPE31720.1 - 0.00024 20.9 0.3 0.00033 20.4 0.3 1.3 1 0 0 1 1 1 1 Endothelial cell-specific chemotaxis regulator TMEM154 PF15102.6 EPE31720.1 - 0.00071 19.5 0.2 0.0011 18.9 0.2 1.5 1 0 0 1 1 1 1 TMEM154 protein family O-antigen_lig PF13425.6 EPE31720.1 - 0.00075 18.4 0.1 0.0009 18.2 0.1 1.0 1 0 0 1 1 1 1 O-antigen ligase like membrane protein SARAF PF06682.12 EPE31720.1 - 0.00083 19.1 0.9 0.001 18.8 0.9 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis ASFV_J13L PF05568.11 EPE31720.1 - 0.0013 18.5 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 African swine fever virus J13L protein DUF2207 PF09972.9 EPE31720.1 - 0.0041 16.0 0.0 0.0047 15.7 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF5385 PF17359.2 EPE31720.1 - 0.0078 15.8 1.6 0.0078 15.8 1.6 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF5385) Protocadherin PF08374.11 EPE31720.1 - 0.0098 15.9 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Protocadherin AA_permease_2 PF13520.6 EPE31720.1 - 0.012 14.5 0.3 0.015 14.2 0.3 1.1 1 0 0 1 1 1 0 Amino acid permease Mem_trans PF03547.18 EPE31720.1 - 0.012 14.0 0.0 0.012 14.0 0.0 1.1 1 0 0 1 1 1 0 Membrane transport protein LPG_synthase_TM PF03706.13 EPE31720.1 - 0.014 14.9 0.2 0.016 14.7 0.2 1.0 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region YajC PF02699.15 EPE31720.1 - 0.015 15.1 0.5 0.035 14.0 0.5 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit DUF3149 PF11346.8 EPE31720.1 - 0.018 14.7 1.1 0.027 14.1 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Orf78 PF06024.12 EPE31720.1 - 0.02 15.2 0.6 0.02 15.2 0.6 1.8 2 0 0 2 2 2 0 Orf78 (ac78) Adeno_E3_CR2 PF02439.15 EPE31720.1 - 0.024 14.4 7.4 0.042 13.6 7.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3139 PF11337.8 EPE31720.1 - 0.024 15.3 0.0 0.038 14.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) DUF4448 PF14610.6 EPE31720.1 - 0.027 14.3 0.6 0.04 13.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1980 PF09323.10 EPE31720.1 - 0.028 14.3 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2561 PF10812.8 EPE31720.1 - 0.03 14.4 0.0 0.034 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Stevor PF17410.2 EPE31720.1 - 0.036 13.6 2.3 0.047 13.2 2.3 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4330 PF14221.6 EPE31720.1 - 0.05 13.8 4.0 0.23 11.6 1.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4330) Cadherin_C_2 PF16492.5 EPE31720.1 - 0.061 14.1 1.4 0.23 12.2 0.6 2.2 2 1 0 2 2 1 0 Cadherin cytoplasmic C-terminal Phage_holin_3_6 PF07332.11 EPE31720.1 - 0.064 13.3 1.8 0.1 12.7 1.8 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4199 PF13858.6 EPE31720.1 - 0.069 13.5 0.8 0.096 13.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) CD34_antigen PF06365.12 EPE31720.1 - 0.071 12.7 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family SID-1_RNA_chan PF13965.6 EPE31720.1 - 0.097 11.1 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Herpes_gE PF02480.16 EPE31720.1 - 0.099 11.4 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SCIMP PF15050.6 EPE31720.1 - 0.1 13.1 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 SCIMP protein LRR19-TM PF15176.6 EPE31720.1 - 0.11 12.5 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Tmemb_9 PF05434.11 EPE31720.1 - 0.11 12.4 0.2 0.14 12.1 0.2 1.4 1 1 0 1 1 1 0 TMEM9 DUF3328 PF11807.8 EPE31720.1 - 0.13 12.1 0.0 0.18 11.5 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) PrgH PF09480.10 EPE31720.1 - 0.13 11.5 0.1 0.16 11.2 0.1 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) Chloroa_b-bind PF00504.21 EPE31720.1 - 0.14 12.7 0.0 0.17 12.4 0.0 1.1 1 0 0 1 1 1 0 Chlorophyll A-B binding protein SIT PF15330.6 EPE31720.1 - 0.17 12.3 4.8 0.64 10.5 4.8 1.9 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4834 PF16118.5 EPE31720.1 - 0.18 12.8 8.0 0.32 12.0 6.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) DHHC PF01529.20 EPE31720.1 - 0.19 11.8 0.4 0.26 11.4 0.4 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF5305 PF17231.2 EPE31720.1 - 0.21 11.0 0.9 0.3 10.5 0.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) RIFIN PF02009.16 EPE31720.1 - 0.22 11.4 6.1 0.31 10.9 6.1 1.2 1 0 0 1 1 1 0 Rifin Gemini_mov PF01708.16 EPE31720.1 - 0.31 10.8 2.0 0.5 10.2 0.0 2.2 2 1 0 2 2 2 0 Geminivirus putative movement protein DUF2615 PF11027.8 EPE31720.1 - 0.33 11.1 2.7 1.1 9.4 2.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) TMEM132D_C PF15706.5 EPE31720.1 - 0.75 9.6 3.8 0.92 9.3 3.0 1.7 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Glucos_trans_II PF14264.6 EPE31720.1 - 1.5 8.1 8.3 3 7.1 4.5 1.7 1 1 1 2 2 2 0 Glucosyl transferase GtrII DUF3810 PF12725.7 EPE31720.1 - 2.5 7.4 4.4 3.2 7.0 4.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) UPF0258 PF06789.12 EPE31720.1 - 3.5 7.7 5.6 6 7.0 5.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Vpu PF00558.19 EPE31720.1 - 6.2 6.7 8.4 7.5 6.4 7.8 1.5 1 1 1 2 2 1 0 Vpu protein EzrA PF06160.12 EPE31720.1 - 8.1 4.5 5.2 11 4.0 5.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DJ-1_PfpI PF01965.24 EPE31721.1 - 1.3e-13 51.0 0.0 2.5e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EPE31721.1 - 0.00022 21.0 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 ThiJ/PfpI family-like SNO PF01174.19 EPE31721.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Mito_carr PF00153.27 EPE31722.1 - 7.8e-47 157.1 5.4 1.3e-16 60.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein APH PF01636.23 EPE31723.1 - 1.2e-11 45.1 0.0 1.3e-10 41.7 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EPE31723.1 - 0.014 14.3 0.6 1.1 8.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1679) NOC3p PF07540.11 EPE31724.1 - 1.3e-30 105.7 0.2 3.7e-30 104.2 0.2 1.9 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 EPE31724.1 - 1.1e-27 97.1 0.1 3.1e-27 95.7 0.0 1.8 2 0 0 2 2 2 1 CBF/Mak21 family UPF0113 PF03657.13 EPE31725.1 - 2.4e-25 88.6 0.0 3.6e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 EPE31725.1 - 1.8e-23 82.9 0.0 2.5e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 EPE31725.1 - 0.062 13.3 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 PUA domain Methyltransf_2 PF00891.18 EPE31726.1 - 2.1e-09 37.0 0.0 8e-09 35.1 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain DEAD PF00270.29 EPE31727.1 - 4.1e-33 114.6 0.0 6.6e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE31727.1 - 1.3e-18 67.3 0.0 6.6e-18 65.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE31727.1 - 1.9e-05 24.8 0.0 7.9e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PI-PLC-C1 PF16670.5 EPE31729.1 - 0.09 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide phospholipase C, Ca2+-dependent Thiamine_BP PF01910.17 EPE31730.1 - 1.5e-29 101.7 0.0 1.8e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Med2 PF11214.8 EPE31730.1 - 0.075 13.2 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 2 DUF3328 PF11807.8 EPE31731.1 - 2e-25 89.9 0.9 2.5e-25 89.6 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PhrC_PhrF PF11131.8 EPE31732.1 - 0.0032 17.0 0.6 0.0057 16.2 0.6 1.5 1 0 0 1 1 1 1 Rap-phr extracellular signalling AvrM_N PF18247.1 EPE31732.1 - 0.012 15.6 0.2 7.9 6.5 0.0 3.6 1 1 3 4 4 4 0 Flax-rust effector AvrM N-terminal domain PHP_C PF13263.6 EPE31732.1 - 0.032 14.0 3.4 2.8 7.8 0.1 3.7 1 1 2 4 4 4 0 PHP-associated Rod_cone_degen PF15201.6 EPE31732.1 - 0.037 14.1 1.4 9.8 6.4 0.0 3.4 1 1 3 4 4 4 0 Progressive rod-cone degeneration Methyltransf_2 PF00891.18 EPE31733.1 - 5.2e-25 88.0 0.0 8.5e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EPE31733.1 - 0.0083 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE31733.1 - 0.0087 16.8 0.0 0.022 15.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE31733.1 - 0.013 15.3 0.0 0.094 12.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 EPE31733.1 - 0.063 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.6 EPE31733.1 - 0.14 12.8 0.0 0.39 11.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF3328 PF11807.8 EPE31734.1 - 1.3e-24 87.2 0.0 1.3e-23 83.9 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Tyrosinase PF00264.20 EPE31735.1 - 3.4e-33 115.8 0.9 1.2e-32 114.0 0.9 1.8 1 1 0 1 1 1 1 Common central domain of tyrosinase p450 PF00067.22 EPE31736.1 - 3.8e-57 194.1 0.0 4.9e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRP7 PF12923.7 EPE31738.1 - 0.078 13.1 0.2 0.11 12.7 0.2 1.3 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain CorA PF01544.18 EPE31740.1 - 2.3e-11 43.6 7.2 4.3e-10 39.4 7.2 2.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein bZIP_2 PF07716.15 EPE31740.1 - 0.00018 21.5 3.5 0.00018 21.5 3.5 2.7 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 EPE31740.1 - 0.00047 20.2 1.5 0.00047 20.2 1.5 2.1 3 0 0 3 3 3 1 bZIP transcription factor WD40_alt PF14077.6 EPE31740.1 - 0.023 14.5 0.6 0.077 12.9 0.6 1.8 1 0 0 1 1 1 0 Alternative WD40 repeat motif Syntaxin_2 PF14523.6 EPE31740.1 - 0.027 14.8 0.2 0.89 10.0 0.0 3.1 3 0 0 3 3 3 0 Syntaxin-like protein TPD52 PF04201.15 EPE31740.1 - 0.098 12.3 2.3 0.17 11.5 0.1 2.5 3 0 0 3 3 3 0 Tumour protein D52 family MscS_TM PF12794.7 EPE31740.1 - 0.18 10.6 0.2 0.3 9.9 0.2 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Striatin PF08232.12 EPE31740.1 - 0.42 11.2 3.0 0.4 11.3 0.4 2.3 1 1 1 2 2 2 0 Striatin family bZIP_Maf PF03131.17 EPE31740.1 - 1 9.9 7.6 0.045 14.3 1.4 1.9 2 0 0 2 2 1 0 bZIP Maf transcription factor BST2 PF16716.5 EPE31740.1 - 2.1 9.0 5.4 22 5.7 0.1 3.3 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 ATG16 PF08614.11 EPE31740.1 - 6.7 6.9 9.6 0.53 10.5 2.8 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Glyco_hydro2_C5 PF18565.1 EPE31741.1 - 1.5e-21 76.2 0.1 1.9e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 DUF4715 PF15835.5 EPE31741.1 - 4.6e-05 23.5 0.0 0.054 13.6 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4715) Invasin_D3 PF09134.10 EPE31741.1 - 0.0007 19.9 1.7 0.0018 18.5 1.7 1.7 1 1 0 1 1 1 1 Invasin, domain 3 Sigma70_r4_2 PF08281.12 EPE31741.1 - 0.041 13.6 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 Big_1 PF02369.16 EPE31741.1 - 0.043 13.8 1.2 0.16 12.0 1.1 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) AAA_5 PF07728.14 EPE31743.1 - 1.6e-121 400.7 0.0 1.1e-20 74.0 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EPE31743.1 - 8.4e-59 196.3 5.2 1.1e-22 80.3 0.0 5.6 6 0 0 6 6 4 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 EPE31743.1 - 8.9e-32 109.3 0.3 8.7e-31 106.2 0.0 2.8 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_7 PF12775.7 EPE31743.1 - 5e-30 104.4 0.6 2e-05 24.2 0.0 7.0 6 1 0 6 6 6 6 P-loop containing dynein motor region AAA_3 PF07726.11 EPE31743.1 - 8e-29 100.2 0.0 8.3e-11 41.9 0.0 8.1 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE31743.1 - 3.3e-28 99.2 19.3 4.4e-05 23.9 0.2 9.1 7 2 0 7 7 6 6 AAA ATPase domain AAA PF00004.29 EPE31743.1 - 4e-27 95.2 0.0 0.00041 20.8 0.0 7.0 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 EPE31743.1 - 2e-23 82.7 0.0 0.00011 22.3 0.0 8.2 8 0 0 8 8 6 4 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 EPE31743.1 - 1.5e-22 80.3 4.7 0.015 15.6 0.0 9.2 8 1 0 8 8 7 5 AAA domain AAA_6 PF12774.7 EPE31743.1 - 2e-22 79.6 0.0 0.0012 17.9 0.0 8.3 8 1 0 8 8 8 4 Hydrolytic ATP binding site of dynein motor region Sigma54_activat PF00158.26 EPE31743.1 - 1.3e-20 73.8 0.1 0.052 13.2 0.0 6.6 6 0 0 6 6 6 5 Sigma-54 interaction domain AAA_33 PF13671.6 EPE31743.1 - 2e-20 73.4 0.1 0.0049 17.0 0.0 7.0 6 0 0 6 6 6 4 AAA domain TsaE PF02367.17 EPE31743.1 - 2.2e-18 66.4 2.4 0.0061 16.6 0.1 6.5 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EPE31743.1 - 1.9e-17 64.1 1.2 0.024 15.2 0.0 7.0 6 0 0 6 6 6 2 AAA domain AAA_14 PF13173.6 EPE31743.1 - 2.6e-17 63.1 0.0 0.021 14.8 0.0 7.2 6 0 0 6 6 6 3 AAA domain NACHT PF05729.12 EPE31743.1 - 1.3e-16 60.9 3.2 0.075 12.9 0.1 6.3 6 0 0 6 6 5 5 NACHT domain AAA_30 PF13604.6 EPE31743.1 - 3.2e-16 59.6 0.0 0.0069 16.1 0.0 8.1 8 1 0 8 8 7 3 AAA domain ABC_tran PF00005.27 EPE31743.1 - 3.8e-15 56.6 4.9 0.03 14.9 0.0 7.5 7 0 0 7 7 6 3 ABC transporter T2SSE PF00437.20 EPE31743.1 - 2.7e-14 52.9 0.7 0.037 13.1 0.0 6.6 6 0 0 6 6 6 3 Type II/IV secretion system protein Zeta_toxin PF06414.12 EPE31743.1 - 5.5e-14 51.9 3.3 0.054 12.8 0.0 7.2 7 0 0 7 7 6 2 Zeta toxin Sigma54_activ_2 PF14532.6 EPE31743.1 - 9.4e-14 51.7 0.7 0.00038 20.6 0.0 6.3 6 0 0 6 6 6 2 Sigma-54 interaction domain RNA_helicase PF00910.22 EPE31743.1 - 1.5e-13 51.1 1.5 0.15 12.5 0.0 7.0 6 0 0 6 6 6 2 RNA helicase RsgA_GTPase PF03193.16 EPE31743.1 - 2.1e-13 50.5 1.3 0.05 13.5 0.1 6.0 6 0 0 6 6 5 3 RsgA GTPase AAA_29 PF13555.6 EPE31743.1 - 1.3e-11 44.0 0.3 0.63 9.8 0.0 6.5 6 0 0 6 6 6 1 P-loop containing region of AAA domain RuvB_N PF05496.12 EPE31743.1 - 3.4e-11 43.1 3.6 0.047 13.4 0.0 6.9 7 0 0 7 7 7 2 Holliday junction DNA helicase RuvB P-loop domain SRP54 PF00448.22 EPE31743.1 - 2.8e-10 40.1 1.1 1.6 8.4 0.0 6.3 7 0 0 7 7 5 2 SRP54-type protein, GTPase domain AAA_28 PF13521.6 EPE31743.1 - 3.3e-10 40.4 5.4 0.26 11.5 0.0 7.3 7 0 0 7 7 6 2 AAA domain AAA_25 PF13481.6 EPE31743.1 - 9.3e-10 38.4 0.4 1.3 8.6 0.0 6.1 5 0 0 5 5 5 1 AAA domain AAA_19 PF13245.6 EPE31743.1 - 2.3e-09 37.7 2.9 1.4 9.3 0.0 6.9 6 0 0 6 6 5 1 AAA domain ATPase_2 PF01637.18 EPE31743.1 - 6.6e-09 36.0 0.0 0.18 11.7 0.0 6.8 7 0 0 7 7 6 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 EPE31743.1 - 7.7e-09 35.6 0.1 0.29 10.8 0.0 6.1 6 0 0 6 6 6 2 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 EPE31743.1 - 1.9e-08 34.2 2.0 0.058 13.1 0.0 5.6 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 EPE31743.1 - 2.6e-08 34.0 0.3 0.35 10.8 0.0 5.9 6 0 0 6 6 5 1 Rad17 P-loop domain Mg_chelatase PF01078.21 EPE31743.1 - 2.7e-08 33.5 2.4 10 5.4 0.0 8.1 9 0 0 9 9 8 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EPE31743.1 - 4.2e-08 33.1 0.2 0.75 9.5 0.0 5.9 5 0 0 5 5 5 1 IstB-like ATP binding protein AAA_24 PF13479.6 EPE31743.1 - 4.3e-08 33.1 0.1 3.1 7.5 0.0 6.0 6 0 0 6 6 6 0 AAA domain TniB PF05621.11 EPE31743.1 - 4.3e-08 32.8 0.0 0.47 9.8 0.0 6.2 6 0 0 6 6 6 1 Bacterial TniB protein Roc PF08477.13 EPE31743.1 - 1e-06 29.0 2.6 9.7 6.4 0.1 6.3 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EPE31743.1 - 1.6e-06 28.1 6.8 1.2 9.0 0.0 6.0 6 0 0 6 6 6 2 NTPase cobW PF02492.19 EPE31743.1 - 1.5e-05 24.7 7.3 0.12 12.0 0.1 5.7 6 0 0 6 6 6 1 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 EPE31743.1 - 2.3e-05 23.7 4.0 5.6 6.0 0.1 5.1 6 0 0 6 6 4 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 EPE31743.1 - 3.5e-05 23.1 4.4 19 4.3 0.0 6.3 6 0 0 6 6 6 0 NB-ARC domain MMR_HSR1 PF01926.23 EPE31743.1 - 6.9e-05 22.9 4.7 5.3 7.2 0.0 6.3 7 0 0 7 7 5 0 50S ribosome-binding GTPase CbiA PF01656.23 EPE31743.1 - 0.00011 22.3 4.4 2.5 8.2 0.0 5.4 4 0 0 4 4 4 1 CobQ/CobB/MinD/ParA nucleotide binding domain TIP49 PF06068.13 EPE31743.1 - 0.00033 20.0 0.8 26 3.9 0.0 5.1 6 0 0 6 6 5 0 TIP49 P-loop domain dNK PF01712.19 EPE31743.1 - 0.00034 20.5 7.7 13 5.6 0.0 6.0 6 0 0 6 6 6 0 Deoxynucleoside kinase Bac_DnaA PF00308.18 EPE31743.1 - 0.00037 20.4 0.1 35 4.1 0.0 5.3 5 0 0 5 5 5 0 Bacterial dnaA protein ATP_bind_1 PF03029.17 EPE31743.1 - 0.00073 19.4 5.4 27 4.5 0.0 6.3 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein ATPase PF06745.13 EPE31743.1 - 0.001 18.5 0.3 15 4.8 0.0 5.2 5 0 0 5 5 5 0 KaiC DAP3 PF10236.9 EPE31743.1 - 0.0028 16.9 1.1 4.3 6.4 0.0 4.3 5 0 0 5 5 4 0 Mitochondrial ribosomal death-associated protein 3 FtsK_SpoIIIE PF01580.18 EPE31743.1 - 0.0033 16.8 2.4 14 4.9 0.1 5.4 6 0 0 6 6 6 0 FtsK/SpoIIIE family AAA_23 PF13476.6 EPE31743.1 - 0.0035 17.9 29.6 0.72 10.3 0.0 8.7 9 0 0 9 9 6 2 AAA domain KAP_NTPase PF07693.14 EPE31743.1 - 0.0037 16.5 0.0 16 4.6 0.0 4.9 6 0 0 6 6 4 0 KAP family P-loop domain Septin PF00735.18 EPE31743.1 - 0.0065 15.8 1.0 20 4.4 0.1 4.8 5 0 0 5 5 5 0 Septin PRK PF00485.18 EPE31743.1 - 0.0081 15.9 2.1 9.2 6.0 0.0 4.8 6 0 0 6 6 3 0 Phosphoribulokinase / Uridine kinase family Ploopntkinase3 PF18751.1 EPE31743.1 - 0.01 15.7 0.1 7.1 6.5 0.0 4.2 4 0 0 4 4 4 0 P-loop Nucleotide Kinase3 SRPRB PF09439.10 EPE31743.1 - 0.014 14.9 8.6 50 3.2 0.0 6.9 8 0 0 8 8 7 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EPE31743.1 - 0.02 14.1 3.7 19 4.3 0.0 5.3 6 0 0 6 6 5 0 G-protein alpha subunit Thymidylate_kin PF02223.17 EPE31743.1 - 0.021 14.5 4.3 28 4.3 0.0 5.9 7 0 0 7 7 5 0 Thymidylate kinase PhoH PF02562.16 EPE31743.1 - 0.024 14.1 0.6 17 4.8 0.0 4.6 5 0 0 5 5 5 0 PhoH-like protein MobB PF03205.14 EPE31743.1 - 0.043 13.7 9.2 6.1 6.7 0.1 6.4 7 0 0 7 7 7 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 EPE31743.1 - 0.055 12.4 0.7 12 4.8 0.2 3.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 EPE31743.1 - 0.097 12.5 4.5 5.4 6.7 0.0 5.1 6 0 0 6 6 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Arf PF00025.21 EPE31743.1 - 0.2 11.1 1.1 32 3.9 0.0 4.2 4 0 0 4 4 4 0 ADP-ribosylation factor family AAA_15 PF13175.6 EPE31743.1 - 0.39 10.4 6.9 45 3.6 0.0 5.1 5 1 1 6 6 5 0 AAA ATPase domain SKI PF01202.22 EPE31743.1 - 1.8 8.7 5.2 28 4.8 0.0 4.5 5 0 0 5 5 3 0 Shikimate kinase Ribosomal_L12 PF00542.19 EPE31744.1 - 1.4e-19 70.2 4.7 6.2e-19 68.1 3.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EPE31744.1 - 2.8e-06 27.0 13.8 8.7e-06 25.4 0.1 3.3 4 0 0 4 4 4 2 Ribosomal protein L7/L12 dimerisation domain Phage_capsid PF05065.13 EPE31744.1 - 0.078 12.3 0.2 0.14 11.4 0.1 1.5 2 0 0 2 2 2 0 Phage capsid family CTK3 PF12243.8 EPE31745.1 - 4.6e-50 168.7 0.5 6.9e-50 168.2 0.5 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EPE31745.1 - 1.3e-22 79.7 9.8 1.3e-22 79.7 9.8 2.1 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus HEPN_DZIP3 PF18738.1 EPE31745.1 - 0.004 16.9 0.2 0.0097 15.7 0.2 1.6 1 0 0 1 1 1 1 DZIP3/ hRUL138-like HEPN DUF3873 PF12989.7 EPE31745.1 - 0.078 13.4 0.3 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) P5CR_dimer PF14748.6 EPE31746.1 - 3.3e-36 123.7 5.2 6.7e-36 122.7 5.2 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EPE31746.1 - 1.7e-16 60.5 0.0 5.4e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Hat1_N PF10394.9 EPE31747.1 - 1.1e-47 162.3 0.2 2.1e-47 161.3 0.2 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Zip PF02535.22 EPE31748.1 - 5.2e-37 127.8 15.3 6e-29 101.3 5.8 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter WD40 PF00400.32 EPE31749.1 - 3.9e-40 135.1 17.8 1.4e-07 32.0 0.1 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 EPE31749.1 - 4.8e-10 39.2 0.8 8.4e-10 38.4 0.8 1.4 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EPE31749.1 - 2e-09 37.6 1.5 0.029 14.6 0.0 6.1 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPE31749.1 - 5.2e-06 25.4 6.1 0.17 10.5 0.1 5.3 1 1 5 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EPE31749.1 - 1.7e-05 24.3 0.0 0.076 12.3 0.0 3.1 1 1 2 3 3 3 2 WD40-like domain F-box PF00646.33 EPE31749.1 - 0.00025 20.8 0.7 0.0005 19.9 0.7 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.6 EPE31749.1 - 0.028 14.0 5.9 0.036 13.7 1.1 2.9 1 1 2 3 3 3 0 PQQ-like domain E1_dh PF00676.20 EPE31750.1 - 3.7e-114 380.7 0.2 4.5e-114 380.4 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EPE31750.1 - 4e-05 23.0 0.1 6.8e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EPE31750.1 - 0.025 14.4 1.5 0.05 13.4 1.5 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Asp PF00026.23 EPE31751.1 - 6.4e-08 32.4 0.0 2e-07 30.8 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Insulin_TMD PF17870.1 EPE31751.1 - 0.00058 19.9 0.3 0.0014 18.6 0.3 1.6 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment TAXi_N PF14543.6 EPE31751.1 - 0.044 14.0 0.1 0.086 13.1 0.1 1.4 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal DUF4448 PF14610.6 EPE31751.1 - 0.053 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) SKG6 PF08693.10 EPE31751.1 - 5.4 6.5 8.1 0.38 10.2 2.4 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Ank_2 PF12796.7 EPE31753.1 - 7.1e-29 100.2 3.5 1e-09 38.8 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE31753.1 - 1.3e-26 92.6 5.3 9.2e-07 29.3 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE31753.1 - 1.1e-24 86.1 8.0 1.4e-08 34.8 0.2 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE31753.1 - 2.7e-24 82.6 0.3 3.7e-05 23.8 0.0 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 EPE31753.1 - 1.1e-22 79.4 4.3 7e-07 29.4 0.0 5.6 3 1 2 5 5 5 4 Ankyrin repeat FBPase PF00316.20 EPE31753.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Sacchrp_dh_NADP PF03435.18 EPE31753.1 - 0.15 12.3 0.1 3 8.1 0.0 2.7 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain CTD_bind PF04818.13 EPE31756.1 - 1.8e-19 70.3 0.1 3.8e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.8 EPE31756.1 - 0.0032 17.4 0.2 0.0059 16.6 0.2 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CREPT PF16566.5 EPE31756.1 - 0.0098 16.1 2.3 0.012 15.8 0.1 2.1 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour DUF3277 PF11681.8 EPE31756.1 - 0.02 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) COX7a PF02238.15 EPE31757.1 - 4.6e-19 68.6 5.1 5.9e-19 68.2 5.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII PPR_2 PF13041.6 EPE31758.1 - 0.097 12.9 0.0 17 5.7 0.1 3.0 3 0 0 3 3 3 0 PPR repeat family Ribonuc_red_sm PF00268.21 EPE31758.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain 2TM PF13239.6 EPE31759.1 - 0.062 13.6 3.7 2 8.8 0.9 2.4 2 0 0 2 2 2 0 2TM domain Phage_holin_3_6 PF07332.11 EPE31759.1 - 0.11 12.6 4.4 0.14 12.2 0.2 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III EHN PF06441.12 EPE31760.1 - 1.2e-30 106.0 0.1 1.9e-30 105.4 0.1 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EPE31760.1 - 4.9e-16 59.1 0.0 9.8e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE31760.1 - 6.3e-06 26.9 2.3 1.5e-05 25.7 2.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family CTP_transf_like PF01467.26 EPE31761.1 - 1.3e-21 77.3 0.0 1.7e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like TFX_C PF14601.6 EPE31761.1 - 0.18 11.8 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term APH PF01636.23 EPE31762.1 - 1.1e-07 32.0 0.0 0.00041 20.3 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Aldo_ket_red PF00248.21 EPE31763.1 - 6.7e-53 179.8 0.0 8.3e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1929 PF09118.11 EPE31765.1 - 4e-22 78.3 0.5 1.4e-21 76.6 0.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) F5_F8_type_C PF00754.25 EPE31765.1 - 2.2e-20 73.1 1.5 5.3e-20 71.8 1.5 1.6 1 0 0 1 1 1 1 F5/8 type C domain Kelch_6 PF13964.6 EPE31765.1 - 1.3e-05 25.3 8.5 0.19 12.1 0.0 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 EPE31765.1 - 0.00029 20.4 2.1 0.77 9.4 0.1 4.2 4 0 0 4 4 4 2 Kelch motif PD40 PF07676.12 EPE31765.1 - 0.024 14.5 0.4 1.2 9.2 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Glyoxal_oxid_N PF07250.11 EPE31765.1 - 0.061 12.5 0.3 0.49 9.6 0.1 2.3 2 0 0 2 2 2 0 Glyoxal oxidase N-terminus Glyco_trans_1_4 PF13692.6 EPE31766.1 - 3.9e-11 43.5 0.2 1.1e-10 42.1 0.2 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EPE31766.1 - 1.3e-10 41.1 0.0 6.2e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF3492 PF11997.8 EPE31766.1 - 0.0012 18.7 0.0 0.0037 17.1 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3492) DUF1430 PF07242.11 EPE31766.1 - 9.2 6.6 12.7 32 4.9 12.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) Spherulin4 PF12138.8 EPE31767.1 - 2e-63 214.2 0.1 2.3e-63 214.0 0.1 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Spherulin4 PF12138.8 EPE31768.1 - 1.3e-67 228.0 0.0 1.4e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Epimerase PF01370.21 EPE31769.1 - 1.4e-37 129.5 0.0 7.5e-36 123.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE31769.1 - 2.2e-34 119.4 0.0 4.1e-25 88.9 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EPE31769.1 - 7.8e-08 31.8 0.0 3.6e-05 23.1 0.0 3.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EPE31769.1 - 2.2e-07 30.2 0.0 0.00015 20.8 0.0 2.5 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EPE31769.1 - 6.9e-07 28.7 0.0 2.1e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein KR PF08659.10 EPE31769.1 - 4.3e-05 23.5 0.0 0.00012 22.0 0.0 1.7 1 1 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.14 EPE31769.1 - 0.0056 16.3 0.2 0.21 11.2 0.1 2.7 2 1 1 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain APH PF01636.23 EPE31771.1 - 8e-14 52.1 0.0 1.3e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE31771.1 - 0.00014 21.5 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EPE31771.1 - 0.00088 18.9 0.1 0.047 13.3 0.0 2.2 2 0 0 2 2 2 2 RIO1 family HET PF06985.11 EPE31772.1 - 2.9e-27 95.8 0.0 4.8e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GSDH PF07995.11 EPE31773.1 - 4.9e-06 26.1 0.9 0.0017 17.8 0.1 2.8 3 0 0 3 3 3 2 Glucose / Sorbosone dehydrogenase SGL PF08450.12 EPE31773.1 - 0.00088 18.9 0.1 0.011 15.3 0.0 2.6 3 1 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region RgpF PF05045.12 EPE31774.1 - 0.09 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Rhamnan synthesis protein F FBD PF08387.10 EPE31775.1 - 0.082 12.8 0.3 0.16 11.9 0.3 1.5 1 0 0 1 1 1 0 FBD BTB PF00651.31 EPE31778.1 - 3.5e-07 30.4 0.0 1e-06 28.9 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain Stm1_N PF09598.10 EPE31779.1 - 2.1e-14 54.1 3.7 2.1e-14 54.1 3.7 4.2 4 2 1 5 5 5 1 Stm1 HABP4_PAI-RBP1 PF04774.15 EPE31779.1 - 3.7e-07 31.0 2.9 3.7e-07 31.0 2.9 3.3 3 2 1 4 4 4 1 Hyaluronan / mRNA binding family bZIP_1 PF00170.21 EPE31780.1 - 2.2e-06 27.7 6.0 3.7e-06 26.9 6.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPE31780.1 - 0.66 10.1 8.4 0.67 10.1 7.2 1.6 1 1 0 1 1 1 0 Basic region leucine zipper LIM PF00412.22 EPE31782.1 - 0.00014 22.0 3.7 0.00022 21.4 0.9 2.4 2 0 0 2 2 2 1 LIM domain Med10 PF09748.9 EPE31783.1 - 6.9e-41 139.0 0.0 7.9e-41 138.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex KAR PF15222.6 EPE31783.1 - 0.1 12.9 0.1 0.23 11.8 0.2 1.6 2 0 0 2 2 2 0 Kidney androgen-regulated p450 PF00067.22 EPE31784.1 - 2.5e-50 171.6 0.0 4.3e-50 170.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 EPE31785.1 - 8.1e-23 80.7 3.9 1.8e-22 79.6 3.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE31785.1 - 0.012 15.7 0.7 0.028 14.5 0.7 1.6 1 0 0 1 1 1 0 Berberine and berberine like MFS_1 PF07690.16 EPE31788.1 - 1.2e-44 152.7 45.4 2.5e-44 151.6 45.4 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE31788.1 - 2.6e-09 36.5 8.3 2.6e-09 36.5 8.3 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EPE31788.1 - 1.1e-06 27.3 9.7 1.1e-06 27.3 9.7 1.7 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zinc_ribbon_16 PF17034.5 EPE31789.1 - 8.7e-16 58.3 8.2 2.1e-15 57.1 8.2 1.6 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EPE31789.1 - 2.6e-05 23.8 6.6 6.9e-05 22.4 6.6 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Efg1 PF10153.9 EPE31790.1 - 1.1e-36 125.7 7.9 1.1e-36 125.7 7.9 2.0 2 0 0 2 2 2 1 rRNA-processing protein Efg1 dsrm PF00035.26 EPE31791.1 - 3e-06 27.8 0.5 6.5e-05 23.6 0.0 2.7 3 0 0 3 3 3 1 Double-stranded RNA binding motif PTS_2-RNA PF01885.16 EPE31792.1 - 1.6e-66 223.8 0.0 2e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.17 EPE31792.1 - 0.19 11.8 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 La domain FoP_duplication PF13865.6 EPE31792.1 - 6.2 7.5 30.8 2.3 8.8 4.7 2.3 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Hen1_L PF12623.7 EPE31793.1 - 0.13 11.3 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 DSPc PF00782.20 EPE31794.1 - 8e-21 74.2 0.0 4.7e-18 65.3 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EPE31794.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EPE31794.1 - 0.0088 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 EPE31794.1 - 0.15 12.4 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain Formyl_trans_N PF00551.19 EPE31797.1 - 1.6e-40 138.8 0.0 1.8e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase HTHP PF11534.8 EPE31797.1 - 0.028 14.8 0.0 0.054 13.9 0.0 1.4 1 0 0 1 1 1 0 Hexameric tyrosine-coordinated heme protein (HTHP) Pkinase PF00069.25 EPE31798.1 - 2.1e-46 158.5 0.0 3.1e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE31798.1 - 7.1e-25 87.8 0.0 1.1e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE31798.1 - 7e-08 32.1 0.0 9.9e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EPE31798.1 - 2.1e-05 23.7 0.0 2.1e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EPE31798.1 - 0.0017 18.4 0.1 0.036 14.0 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EPE31798.1 - 0.012 15.0 0.0 0.036 13.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EPE31798.1 - 0.082 12.0 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 MDM31_MDM32 PF08118.11 EPE31799.1 - 5.4e-257 853.6 0.7 7.1e-257 853.2 0.7 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins TraH_2 PF06871.11 EPE31799.1 - 0.019 14.6 0.1 0.045 13.4 0.1 1.6 1 0 0 1 1 1 0 TraH_2 KH_8 PF17903.1 EPE31800.1 - 0.00012 22.1 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EPE31800.1 - 0.017 15.0 0.8 0.034 14.0 0.8 1.5 1 0 0 1 1 1 0 KH domain HSP20 PF00011.21 EPE31801.1 - 1.9e-14 53.6 0.1 5.4e-09 36.1 0.1 2.5 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EPE31801.1 - 0.0021 17.6 0.3 0.028 14.0 0.3 2.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DUF4148 PF13663.6 EPE31801.1 - 0.17 12.1 0.1 0.38 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) YTH PF04146.15 EPE31802.1 - 1.7e-63 213.5 0.0 3.9e-63 212.3 0.0 1.6 1 0 0 1 1 1 1 YT521-B-like domain Pkinase PF00069.25 EPE31803.1 - 2e-56 191.3 0.0 2.7e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE31803.1 - 6.9e-20 71.4 0.0 1.1e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE31803.1 - 2.5e-07 30.3 0.0 4.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EPE31803.1 - 5.1e-05 22.7 0.1 8.6e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EPE31803.1 - 0.00011 21.3 0.0 0.00017 20.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EPE31803.1 - 0.00028 20.9 0.4 0.079 12.9 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EPE31803.1 - 0.013 15.1 0.3 0.033 13.8 0.3 1.6 1 1 0 1 1 1 0 RIO1 family Promethin PF16015.5 EPE31805.1 - 2.5e-30 104.5 17.0 3.1e-30 104.2 17.0 1.1 1 0 0 1 1 1 1 Promethin DUF2417 PF10329.9 EPE31805.1 - 0.057 12.8 2.7 0.067 12.6 2.7 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DUF2070 PF09843.9 EPE31805.1 - 0.38 9.0 3.1 0.44 8.8 3.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FA_desaturase PF00487.24 EPE31805.1 - 3.3 7.5 7.3 4.1 7.2 7.3 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Ank_2 PF12796.7 EPE31806.1 - 3.3e-69 229.5 10.2 1.6e-10 41.4 0.3 9.0 5 2 4 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE31806.1 - 3.2e-45 151.9 8.5 3.8e-05 24.1 0.1 12.5 8 4 6 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE31806.1 - 8.9e-35 114.8 7.0 0.9 10.3 0.0 17.6 19 0 0 19 19 19 10 Ankyrin repeat Ank PF00023.30 EPE31806.1 - 2.6e-33 113.0 15.0 0.053 14.0 0.0 15.5 15 1 0 15 15 15 10 Ankyrin repeat Ank_5 PF13857.6 EPE31806.1 - 3.4e-31 106.9 17.0 0.001 19.3 0.0 10.3 6 2 3 10 10 10 9 Ankyrin repeats (many copies) F-box-like PF12937.7 EPE31806.1 - 0.0061 16.4 0.2 0.018 14.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like Methyltransf_25 PF13649.6 EPE31807.1 - 3.4e-12 46.9 0.0 6e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE31807.1 - 9.3e-10 39.2 0.0 1.9e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE31807.1 - 1.3e-09 38.1 0.0 6.7e-09 35.8 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE31807.1 - 6.9e-09 36.3 0.0 1.2e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE31807.1 - 1.5e-06 28.1 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EPE31807.1 - 0.0012 18.0 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase DUF938 PF06080.12 EPE31807.1 - 0.0031 17.3 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MTS PF05175.14 EPE31807.1 - 0.0039 16.7 0.0 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF4888 PF16229.5 EPE31807.1 - 0.005 16.8 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4888) Methyltransf_4 PF02390.17 EPE31807.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 EPE31807.1 - 0.018 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 EPE31807.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EPE31807.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Isochorismatase PF00857.20 EPE31808.1 - 3.5e-20 72.9 0.0 4.8e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family ABC_tran PF00005.27 EPE31810.1 - 9e-51 172.0 0.0 2.4e-26 92.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPE31810.1 - 3.7e-33 115.4 30.2 1.3e-26 93.8 19.8 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 EPE31810.1 - 6.4e-11 42.6 2.6 0.023 14.5 0.0 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPE31810.1 - 2.9e-09 36.7 5.0 0.025 14.0 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 EPE31810.1 - 4.8e-07 29.7 0.2 0.001 18.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EPE31810.1 - 3e-06 27.7 0.0 0.07 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EPE31810.1 - 3.8e-06 26.5 1.4 0.013 15.2 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 EPE31810.1 - 8.9e-06 25.3 0.2 0.012 15.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 EPE31810.1 - 9.5e-06 25.9 0.0 0.0083 16.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 EPE31810.1 - 3.1e-05 23.2 0.8 0.0018 17.4 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 EPE31810.1 - 0.00013 22.5 1.6 0.046 14.2 0.2 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EPE31810.1 - 0.00032 20.7 0.5 0.29 11.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EPE31810.1 - 0.00059 19.6 0.2 1.2 8.8 0.1 3.1 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EPE31810.1 - 0.00076 19.4 1.7 0.47 10.3 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase FtsK_SpoIIIE PF01580.18 EPE31810.1 - 0.00098 18.5 0.3 1.3 8.3 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family cobW PF02492.19 EPE31810.1 - 0.0021 17.7 1.4 0.01 15.4 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 EPE31810.1 - 0.005 16.8 0.3 1.1 9.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 EPE31810.1 - 0.0053 16.8 0.5 1.6 8.7 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.6 EPE31810.1 - 0.0083 16.3 0.0 0.38 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EPE31810.1 - 0.0086 15.8 3.7 0.5 10.0 0.6 2.2 2 0 0 2 2 2 1 AAA ATPase domain Pox_A32 PF04665.12 EPE31810.1 - 0.011 15.2 0.8 0.56 9.6 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA PF00004.29 EPE31810.1 - 0.011 16.2 0.2 5.2 7.5 0.0 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 EPE31810.1 - 0.015 15.5 0.1 5.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 EPE31810.1 - 0.024 14.4 0.0 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 EPE31810.1 - 0.025 15.1 0.5 8.6 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EPE31810.1 - 0.03 14.4 3.0 0.11 12.6 0.3 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 EPE31810.1 - 0.046 13.7 0.6 1.6 8.6 0.2 2.6 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.9 EPE31810.1 - 0.049 12.5 0.6 1.5 7.6 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.17 EPE31810.1 - 0.055 13.2 1.7 3.6 7.3 0.4 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.18 EPE31810.1 - 0.057 12.7 0.2 1.8 7.8 0.1 2.1 2 0 0 2 2 2 0 Septin Zeta_toxin PF06414.12 EPE31810.1 - 0.064 12.5 0.1 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Viral_helicase1 PF01443.18 EPE31810.1 - 0.085 12.6 0.0 0.86 9.3 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 EPE31810.1 - 0.086 12.4 0.3 14 5.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EPE31810.1 - 0.11 12.2 0.4 7.9 6.2 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_14 PF13173.6 EPE31810.1 - 0.17 11.9 0.0 2 8.5 0.0 2.7 4 0 0 4 4 2 0 AAA domain ATPase_2 PF01637.18 EPE31810.1 - 0.24 11.3 0.9 1.2 8.9 0.1 2.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EPE31810.1 - 0.26 11.2 1.1 15 5.5 0.3 2.4 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.6 EPE31810.1 - 0.26 11.0 0.2 4.1 7.1 0.1 2.5 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 EPE31810.1 - 0.32 11.0 1.1 20 5.2 0.1 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) PIP5K PF01504.18 EPE31814.1 - 2.6e-35 122.0 0.3 8e-27 94.2 0.4 2.9 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EPE31814.1 - 1.5e-28 99.7 0.0 2.9e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EPE31814.1 - 8e-12 45.1 10.2 2.3e-11 43.6 10.2 1.8 1 0 0 1 1 1 1 FYVE zinc finger Clr5 PF14420.6 EPE31814.1 - 0.17 12.2 0.4 0.87 9.9 0.2 2.3 2 0 0 2 2 2 0 Clr5 domain baeRF_family5 PF18846.1 EPE31814.1 - 0.34 11.1 2.3 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 FYVE_2 PF02318.16 EPE31814.1 - 1.3 9.3 11.5 0.13 12.4 5.7 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger ABC2_membrane PF01061.24 EPE31815.1 - 1.3e-40 139.1 22.7 2.3e-40 138.3 22.7 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EPE31815.1 - 6.5e-25 88.2 0.0 1.1e-24 87.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EPE31815.1 - 1.1e-06 28.0 24.0 1.1e-06 28.0 24.0 2.1 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 EPE31815.1 - 0.00011 22.1 0.0 0.56 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EPE31815.1 - 0.036 14.0 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EPE31815.1 - 0.091 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EPE31815.1 - 0.091 12.5 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EPE31815.1 - 0.17 12.4 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.21 EPE31816.1 - 4e-40 138.1 0.0 5e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPE31816.1 - 1.5e-06 27.4 0.0 2.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EPE31816.1 - 1.6e-05 23.6 0.0 2.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 EPE31816.1 - 0.00021 20.2 0.0 0.00025 19.9 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 EPE31816.1 - 0.021 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Alliinase_C PF04864.13 EPE31816.1 - 0.068 12.0 0.2 0.48 9.2 0.2 2.1 1 1 1 2 2 2 0 Allinase DnaJ-X PF14308.6 EPE31817.1 - 5e-77 258.1 5.2 5e-77 258.1 5.2 3.4 4 0 0 4 4 4 2 X-domain of DnaJ-containing DnaJ PF00226.31 EPE31817.1 - 2.9e-24 85.0 0.3 8.8e-24 83.4 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain Epimerase PF01370.21 EPE31818.1 - 2.3e-15 56.7 0.0 3.6e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EPE31818.1 - 4.1e-15 55.6 0.0 1.7e-14 53.6 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EPE31818.1 - 7.5e-06 25.3 0.0 5.4e-05 22.5 0.0 2.2 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EPE31818.1 - 3.6e-05 23.3 0.0 0.00026 20.5 0.0 2.2 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EPE31818.1 - 0.015 14.3 0.1 0.044 12.8 0.0 1.6 1 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family EamA PF00892.20 EPE31819.1 - 1.5e-08 34.9 31.1 1.6e-08 34.8 13.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EPE31819.1 - 3.4e-06 26.6 20.3 3.6e-05 23.3 20.3 2.0 1 1 0 1 1 1 1 Triose-phosphate Transporter family 7TMR-DISM_7TM PF07695.11 EPE31819.1 - 0.24 11.3 24.3 0.19 11.6 7.7 2.4 2 1 1 3 3 3 0 7TM diverse intracellular signalling Phage_holin_2_1 PF04971.12 EPE31819.1 - 9.8 6.3 7.3 1.3 9.1 2.1 2.2 2 0 0 2 2 2 0 Bacteriophage P21 holin S TPT PF03151.16 EPE31820.1 - 1.3e-10 41.1 15.5 1.6e-10 40.8 15.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EPE31820.1 - 0.0001 22.4 8.6 0.0001 22.4 8.6 2.6 2 1 0 2 2 2 1 EamA-like transporter family SQS_PSY PF00494.19 EPE31821.1 - 1.7e-33 116.2 0.0 2.3e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase AMP-binding PF00501.28 EPE31822.1 - 3.5e-64 217.0 0.0 1.6e-33 115.9 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EPE31822.1 - 2.6e-10 41.1 0.1 4.7e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AflR PF08493.10 EPE31822.1 - 0.16 11.5 0.2 0.25 10.8 0.2 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein NIBRIN_BRCT_II PF16508.5 EPE31823.1 - 1.7e-33 115.4 0.0 4.3e-33 114.2 0.0 1.7 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 EPE31823.1 - 4.4e-07 30.2 0.1 9.5e-07 29.1 0.1 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EPE31823.1 - 0.06 13.7 0.3 1.1 9.6 0.1 2.9 2 1 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain Cyt-b5 PF00173.28 EPE31824.1 - 8e-14 51.6 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IF4E PF01652.18 EPE31827.1 - 1.1e-53 181.3 0.1 1.3e-53 181.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.12 EPE31828.1 - 2e-24 85.5 0.4 3.7e-24 84.7 0.4 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family WSC PF01822.19 EPE31830.1 - 7e-47 157.5 46.6 1.8e-20 72.9 14.3 3.5 4 0 0 4 4 4 3 WSC domain Mesd PF10185.9 EPE31830.1 - 0.21 11.5 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor Translin PF01997.16 EPE31831.1 - 2.5e-69 233.3 0.0 3e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Translin family TyeA PF09059.10 EPE31831.1 - 0.19 11.8 1.2 0.35 11.0 0.2 2.0 2 0 0 2 2 2 0 TyeA ECM11 PF15463.6 EPE31831.1 - 0.19 12.3 0.1 0.19 12.3 0.1 2.0 2 1 1 3 3 3 0 Extracellular mutant protein 11 NPV_P10 PF05531.12 EPE31831.1 - 0.23 11.9 3.8 14 6.2 0.2 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mannosyl_trans PF05007.13 EPE31832.1 - 4.2e-82 275.9 13.4 6.5e-82 275.3 13.4 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EPE31832.1 - 2.5e-10 40.0 6.5 2.5e-10 40.0 6.5 2.1 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EPE31832.1 - 6.7e-10 39.1 10.8 6.7e-10 39.1 10.8 2.2 2 1 0 2 2 2 1 Glycosyltransferase family 87 F-box-like PF12937.7 EPE31833.1 - 0.0023 17.8 0.2 0.0096 15.8 0.2 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 EPE31833.1 - 1.1 9.3 3.5 2.2 8.2 0.3 2.6 2 0 0 2 2 2 0 F-box domain Peptidase_S10 PF00450.22 EPE31834.1 - 1.3e-70 239.0 0.1 2.5e-70 238.0 0.1 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase Thaumatin PF00314.17 EPE31835.1 - 5.8e-20 71.9 2.5 7.2e-20 71.5 2.5 1.1 1 0 0 1 1 1 1 Thaumatin family Tryp_inh PF17983.1 EPE31835.1 - 4.8 7.3 7.8 8.4 6.6 5.3 2.4 2 0 0 2 2 2 0 Trypsin inhibitors 1,2 and 3 HET PF06985.11 EPE31837.1 - 1.5e-21 77.3 0.3 4.5e-21 75.7 0.0 2.0 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF4222 PF13973.6 EPE31837.1 - 0.27 10.9 0.1 0.27 10.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4222) GATase_5 PF13507.6 EPE31838.1 - 0.033 13.3 0.0 0.045 12.8 0.0 1.1 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Med8 PF10232.9 EPE31841.1 - 3.3e-47 161.1 1.9 4.5e-47 160.6 1.9 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Rotamase PF00639.21 EPE31841.1 - 0.042 14.8 0.0 0.16 13.0 0.0 2.1 1 1 0 1 1 1 0 PPIC-type PPIASE domain T2SSI PF02501.17 EPE31842.1 - 4.3 7.6 6.8 1 9.6 1.3 2.4 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein I SAP PF02037.27 EPE31843.1 - 3.9e-10 39.2 0.4 1.2e-09 37.7 0.4 1.8 1 0 0 1 1 1 1 SAP domain zf-RING_2 PF13639.6 EPE31843.1 - 8.2e-09 35.7 8.9 8.2e-09 35.7 8.9 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EPE31843.1 - 7.3e-06 26.2 7.0 2.2e-05 24.7 7.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EPE31843.1 - 8.4e-05 22.6 6.0 8.4e-05 22.6 6.0 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EPE31843.1 - 0.0017 18.3 5.0 0.0038 17.2 5.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger RNF220 PF15926.5 EPE31843.1 - 0.0046 16.6 0.6 2.9 7.4 0.0 2.3 2 0 0 2 2 2 2 E3 ubiquitin-protein ligase RNF220 PHD PF00628.29 EPE31843.1 - 0.0063 16.4 10.7 0.017 15.0 10.7 1.7 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.8 EPE31843.1 - 0.015 15.5 11.3 0.015 15.5 11.3 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EPE31843.1 - 0.091 12.9 7.4 0.55 10.4 7.6 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 EPE31843.1 - 0.11 12.4 12.5 0.047 13.6 7.1 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 EPE31843.1 - 0.22 11.3 10.1 0.55 10.1 10.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Di19 PF05605.12 EPE31843.1 - 0.26 11.6 3.7 3.9 7.8 0.0 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FANC_SAP PF18081.1 EPE31843.1 - 0.39 10.9 3.5 0.36 11.0 1.5 1.9 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain zf-RING-like PF08746.11 EPE31843.1 - 0.48 10.8 10.2 0.19 12.1 2.7 2.7 2 0 0 2 2 2 0 RING-like domain zf-RING_11 PF17123.5 EPE31843.1 - 1.2 9.0 13.6 0.053 13.3 6.7 2.2 2 0 0 2 2 2 0 RING-like zinc finger RINGv PF12906.7 EPE31843.1 - 1.5 9.0 11.0 3.2 7.9 11.0 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.6 EPE31843.1 - 3.4 7.6 15.3 0.12 12.3 7.8 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE31843.1 - 4 7.4 15.3 0.073 13.0 7.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AltA1 PF16541.5 EPE31844.1 - 1e-09 39.2 2.6 1.4e-09 38.8 2.6 1.1 1 0 0 1 1 1 1 Alternaria alternata allergen 1 FAD_binding_4 PF01565.23 EPE31845.1 - 4.6e-25 88.0 0.7 8e-25 87.2 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.18 EPE31846.1 - 2.3e-08 34.0 14.2 4.5e-08 33.1 14.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE31846.1 - 0.0027 16.8 0.0 0.0056 15.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Oxidored_FMN PF00724.20 EPE31847.1 - 2.2e-59 201.5 0.0 2.7e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EPE31847.1 - 0.005 16.0 0.0 0.076 12.1 0.0 2.3 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) HET PF06985.11 EPE31848.1 - 3.3e-24 85.9 0.1 6.7e-24 84.9 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) 4HBT_3 PF13622.6 EPE31849.1 - 1.4e-56 192.5 0.0 1.6e-56 192.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EPE31849.1 - 0.008 16.5 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 1 Thioesterase superfamily ArfGap PF01412.18 EPE31850.1 - 6.8e-33 113.2 1.9 8.7e-33 112.9 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EPE31850.1 - 2e-21 76.8 16.3 3.3e-21 76.1 16.3 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EPE31850.1 - 9.4e-11 42.2 0.0 9.4e-11 42.2 0.0 2.6 4 0 0 4 4 4 1 PH domain PMEI PF04043.15 EPE31850.1 - 0.059 13.7 0.5 0.26 11.6 0.2 2.2 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor ANAPC9 PF12856.7 EPE31850.1 - 0.13 12.4 2.1 0.33 11.1 2.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 EMP24_GP25L PF01105.24 EPE31850.1 - 2.3 8.1 5.2 4.1 7.3 3.2 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD C2 PF00168.30 EPE31851.1 - 2.7e-12 46.9 0.0 5.2e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain Proteasome PF00227.26 EPE31852.1 - 2e-28 99.2 0.0 2.4e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HCNGP PF07818.13 EPE31853.1 - 3.2e-32 111.0 1.5 5.7e-32 110.2 1.5 1.4 1 0 0 1 1 1 1 HCNGP-like protein Pkinase PF00069.25 EPE31854.1 - 3.5e-75 252.8 0.0 1.3e-74 251.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE31854.1 - 1.6e-38 132.4 0.0 2.5e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EPE31854.1 - 1.2e-16 60.8 0.1 2.6e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EPE31854.1 - 3.1e-10 39.8 0.0 1.8e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EPE31854.1 - 5.5e-07 28.7 0.0 1.8e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 EPE31854.1 - 2.4e-06 27.7 0.0 7.4e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 EPE31854.1 - 9.5e-06 25.7 0.0 7.1e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EPE31854.1 - 0.0018 18.0 0.1 1.8 8.1 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EPE31854.1 - 0.01 15.2 0.1 0.02 14.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EPE31854.1 - 0.07 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 EPE31854.1 - 0.17 10.8 0.0 0.44 9.5 0.0 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase adh_short PF00106.25 EPE31856.1 - 6.2e-21 74.7 3.3 8.7e-21 74.3 3.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE31856.1 - 1.5e-14 54.1 2.9 2e-14 53.7 2.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE31856.1 - 0.00019 21.4 0.1 0.00052 20.0 0.0 1.8 2 0 0 2 2 2 1 KR domain TrkA_N PF02254.18 EPE31856.1 - 0.00076 19.7 2.0 0.27 11.5 0.0 2.6 1 1 0 2 2 2 2 TrkA-N domain NAD_binding_10 PF13460.6 EPE31856.1 - 0.0016 18.3 1.8 0.0028 17.6 1.8 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE31856.1 - 0.013 15.0 0.1 0.019 14.5 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPE31856.1 - 0.067 12.7 0.7 0.18 11.4 0.1 1.9 2 1 1 3 3 3 0 NmrA-like family DUF2321 PF10083.9 EPE31856.1 - 0.084 12.5 0.2 0.39 10.3 0.0 2.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Fungal_trans_2 PF11951.8 EPE31857.1 - 2.1e-60 204.6 5.7 2.6e-60 204.3 5.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE31857.1 - 5.1e-09 36.1 4.5 9.5e-09 35.2 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBM26 PF16738.5 EPE31858.1 - 0.0049 17.1 0.7 0.033 14.4 0.5 2.3 2 0 0 2 2 2 1 Starch-binding module 26 TauD PF02668.16 EPE31859.1 - 7.8e-52 176.7 0.0 1e-51 176.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 EPE31860.1 - 5.3e-24 84.8 69.8 1.7e-23 83.1 46.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BTB PF00651.31 EPE31861.1 - 1.9e-06 28.1 0.0 3.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EPE31862.1 - 0.014 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain FGGY_C PF02782.16 EPE31863.1 - 1.1e-26 93.8 0.0 2e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EPE31863.1 - 4.8e-19 68.9 0.0 1.5e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.21 EPE31864.1 - 1.5e-49 168.5 6.4 1.9e-49 168.1 6.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EPE31864.1 - 8.1e-05 22.7 0.1 0.0002 21.4 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter UreE_C PF05194.12 EPE31864.1 - 0.73 10.4 24.3 2.3 8.7 0.9 3.6 3 0 0 3 3 3 0 UreE urease accessory protein, C-terminal domain SIR2 PF02146.17 EPE31865.1 - 9.5e-31 107.1 0.0 2.4e-30 105.8 0.0 1.7 2 0 0 2 2 2 1 Sir2 family Methyltransf_2 PF00891.18 EPE31865.1 - 1.1e-17 64.1 0.0 1.7e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 EPE31865.1 - 0.00085 19.3 0.3 0.0032 17.5 0.1 2.2 2 0 0 2 2 2 1 Dimerisation domain Dimerisation2 PF16864.5 EPE31865.1 - 0.088 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain DUF5321 PF17254.2 EPE31866.1 - 9.4e-66 220.2 1.5 1.2e-65 219.8 1.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5321) RAMP4 PF06624.12 EPE31866.1 - 0.0032 17.5 0.6 0.01 15.9 0.0 2.1 2 0 0 2 2 2 1 Ribosome associated membrane protein RAMP4 Peptidase_C50 PF03568.17 EPE31867.1 - 1.2e-162 541.6 0.4 5.6e-162 539.4 0.0 2.4 3 0 0 3 3 3 1 Peptidase family C50 CHAT PF12770.7 EPE31867.1 - 0.00056 19.4 0.0 0.011 15.2 0.0 2.7 2 0 0 2 2 2 1 CHAT domain TPR_1 PF00515.28 EPE31868.1 - 4.6e-39 130.7 24.4 3.3e-06 26.7 0.1 9.4 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 EPE31868.1 - 2.9e-36 120.6 23.3 3.8e-07 29.7 0.2 9.3 7 1 2 9 9 9 7 Tetratricopeptide repeat DnaJ PF00226.31 EPE31868.1 - 2.9e-27 94.6 4.0 1.2e-26 92.6 4.0 2.2 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.6 EPE31868.1 - 5.6e-24 84.5 15.4 1.3e-07 32.1 0.7 6.0 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EPE31868.1 - 6.2e-24 83.4 23.8 1.3e-07 31.2 1.8 7.5 7 1 1 8 8 7 4 TPR repeat TPR_19 PF14559.6 EPE31868.1 - 2.3e-22 79.3 23.9 3.9e-09 36.9 0.1 6.7 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EPE31868.1 - 5.3e-20 71.5 15.9 0.00088 19.5 0.0 8.2 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 EPE31868.1 - 2e-18 65.5 19.4 6.7e-05 23.4 0.1 8.8 5 2 4 9 9 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EPE31868.1 - 3.4e-18 64.3 19.4 0.02 15.1 0.0 9.7 10 1 1 11 11 10 5 Tetratricopeptide repeat TPR_9 PF13371.6 EPE31868.1 - 2.2e-14 53.4 14.5 0.0033 17.5 0.0 6.6 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EPE31868.1 - 5.6e-13 48.3 26.1 0.0032 17.7 0.4 8.1 9 0 0 9 9 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE31868.1 - 1.2e-12 47.9 8.6 7.1e-07 29.4 0.2 4.7 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EPE31868.1 - 1.4e-12 46.7 16.8 0.023 14.7 0.0 8.0 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 EPE31868.1 - 3.9e-08 33.4 24.0 0.0093 16.5 0.2 8.9 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 EPE31868.1 - 4e-07 29.5 6.6 0.09 12.0 0.1 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 EPE31868.1 - 4.5e-06 26.8 4.3 0.0028 18.1 0.3 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EPE31868.1 - 2.6e-05 23.9 20.8 0.053 13.4 0.2 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat BTAD PF03704.17 EPE31868.1 - 4.9e-05 23.8 7.9 0.26 11.7 0.5 4.8 2 2 3 5 5 5 2 Bacterial transcriptional activator domain TPR_MalT PF17874.1 EPE31868.1 - 0.00019 21.0 2.5 0.035 13.5 0.4 3.4 1 1 2 3 3 3 2 MalT-like TPR region Alkyl_sulf_dimr PF14863.6 EPE31868.1 - 0.00027 21.4 6.2 1.2 9.6 0.0 4.7 2 2 2 4 4 4 1 Alkyl sulfatase dimerisation TPR_20 PF14561.6 EPE31868.1 - 0.00041 20.6 14.2 0.19 12.1 0.4 5.1 3 3 2 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.8 EPE31868.1 - 0.0045 16.0 7.2 0.075 11.9 0.3 3.3 2 1 0 3 3 3 2 NMDA receptor-regulated protein 1 MIT PF04212.18 EPE31868.1 - 0.011 15.8 7.8 4 7.6 0.1 4.0 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Coatomer_E PF04733.14 EPE31868.1 - 0.014 14.9 2.4 1.7 8.0 0.1 3.0 2 1 1 3 3 3 0 Coatomer epsilon subunit DUF4919 PF16266.5 EPE31868.1 - 0.031 14.2 0.7 2.3 8.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4919) TOM20_plant PF06552.12 EPE31868.1 - 0.046 13.5 3.9 0.73 9.6 0.1 3.3 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Wzy_C_2 PF11846.8 EPE31868.1 - 0.055 13.4 2.6 13 5.6 0.3 3.3 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal HrpB1_HrpK PF09613.10 EPE31868.1 - 0.071 12.8 0.6 6.6 6.4 0.0 3.1 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF4192 PF13830.6 EPE31868.1 - 0.073 13.1 0.9 0.15 12.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Vta1_C PF18097.1 EPE31868.1 - 0.19 11.4 1.4 4.1 7.2 0.0 3.8 4 0 0 4 4 4 0 Vta1 C-terminal domain SNAP PF14938.6 EPE31868.1 - 0.23 10.9 20.8 0.38 10.1 2.5 3.6 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP APP_E2 PF12925.7 EPE31868.1 - 0.53 10.0 12.1 0.58 9.9 0.1 4.3 2 1 3 5 5 5 0 E2 domain of amyloid precursor protein Fis1_TPR_C PF14853.6 EPE31868.1 - 0.62 10.2 13.5 3.2 7.9 0.2 5.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat BTB PF00651.31 EPE31869.1 - 3.2e-05 24.1 0.0 6.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain SDA1 PF05285.12 EPE31869.1 - 0.6 9.5 12.4 0.77 9.1 12.4 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EPE31869.1 - 1.4 7.0 13.9 1.9 6.6 13.9 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EPE31869.1 - 7.3 4.6 20.5 10 4.1 20.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi NTF2 PF02136.20 EPE31873.1 - 5.3e-24 85.1 0.8 7.6e-24 84.6 0.8 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EPE31873.1 - 1.2e-07 31.4 0.0 3e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_11 PF13414.6 EPE31874.1 - 0.0022 17.6 0.3 0.24 11.1 0.1 2.8 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 EPE31874.1 - 0.011 16.0 0.6 0.72 10.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Nro1 PF12753.7 EPE31874.1 - 0.026 13.5 0.0 0.076 12.0 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Hs1pro-1_N PF07231.12 EPE31875.1 - 0.069 12.9 0.5 0.086 12.6 0.5 1.1 1 0 0 1 1 1 0 Hs1pro-1 N-terminus APH PF01636.23 EPE31876.1 - 4.7e-09 36.5 0.0 7.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE31876.1 - 0.034 13.7 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SSrecog PF03531.14 EPE31877.1 - 3.5e-30 103.7 0.7 1.9e-29 101.3 0.0 2.7 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 EPE31877.1 - 9.8e-30 102.8 0.3 5.7e-28 97.2 0.1 2.8 2 0 0 2 2 2 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 EPE31877.1 - 6.2e-25 87.4 0.2 4.4e-24 84.7 0.1 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC45 PF02724.14 EPE31877.1 - 3.5 5.8 8.4 4.9 5.3 8.4 1.3 1 0 0 1 1 1 0 CDC45-like protein NAD_binding_10 PF13460.6 EPE31878.1 - 4.9e-07 29.8 0.0 6.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 EPE31878.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 EPE31878.1 - 0.03 13.4 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SNF2_N PF00176.23 EPE31879.1 - 8.5e-40 136.5 0.1 6.7e-39 133.6 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE31879.1 - 9.3e-22 77.5 0.0 2.7e-21 76.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE31879.1 - 2e-05 24.7 0.0 7.9e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EPE31879.1 - 2.7e-05 23.5 0.1 5.9e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CCDC-167 PF15188.6 EPE31879.1 - 0.097 13.0 1.1 0.54 10.6 0.5 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 GSH_synth_ATP PF03917.17 EPE31880.1 - 2.9e-140 467.3 0.0 3.3e-140 467.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EPE31880.1 - 5.9e-35 119.8 0.0 3.7e-34 117.2 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic glutathione synthase SSB PF00436.25 EPE31881.1 - 3.9e-19 68.6 0.0 4.9e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family EFG_C PF00679.24 EPE31881.1 - 0.012 15.6 0.0 0.03 14.3 0.0 1.6 1 1 0 1 1 1 0 Elongation factor G C-terminus tRNA_anti-codon PF01336.25 EPE31881.1 - 0.028 14.4 0.1 0.038 14.0 0.1 1.4 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain DUF4203 PF13886.6 EPE31882.1 - 2.7e-50 170.8 28.1 3.6e-50 170.4 28.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) HATPase_c PF02518.26 EPE31883.1 - 1.2e-21 77.3 0.1 2.4e-21 76.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPE31883.1 - 1.9e-20 73.1 0.1 3.8e-20 72.1 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPE31883.1 - 1.4e-12 47.4 0.1 3.4e-12 46.2 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 EPE31883.1 - 0.069 13.1 0.0 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Cation_efflux PF01545.21 EPE31884.1 - 1e-18 67.8 4.5 1.3e-18 67.4 4.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EPE31884.1 - 2.1e-10 40.6 0.3 6.4e-10 39.0 0.3 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Glyco_transf_90 PF05686.12 EPE31885.1 - 5.7e-21 74.9 0.1 9.9e-21 74.1 0.1 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 90 NPR3 PF03666.13 EPE31886.1 - 0.52 9.0 11.8 1 8.1 11.8 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NDUFA12 PF05071.16 EPE31887.1 - 2.4e-10 41.1 1.8 2.9e-10 40.8 0.2 1.9 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Erf4 PF10256.9 EPE31888.1 - 1.1e-37 128.7 0.0 1.7e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family ECH_1 PF00378.20 EPE31889.1 - 1.1e-21 77.3 0.0 1.4e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPE31889.1 - 2.6e-05 23.9 0.0 3.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EPE31889.1 - 0.0015 18.5 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 Glycos_transf_1 PF00534.20 EPE31890.1 - 1.5e-31 109.2 0.1 2.7e-30 105.2 0.1 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EPE31890.1 - 4.8e-16 59.2 0.0 1.9e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EPE31890.1 - 2e-12 47.7 0.1 8.6e-12 45.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EPE31890.1 - 2.1e-08 34.7 0.0 6.4e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Pyr_redox_2 PF07992.14 EPE31890.1 - 5e-06 26.0 0.0 1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_trans_1_2 PF13524.6 EPE31890.1 - 2.2e-05 24.7 0.0 5.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 EPE31890.1 - 0.0017 18.5 0.0 1.8 8.6 0.0 2.6 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus NAD_binding_9 PF13454.6 EPE31890.1 - 0.0051 16.8 0.3 0.47 10.4 0.5 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding LRR_4 PF12799.7 EPE31891.1 - 9.3e-21 73.6 43.0 1.9e-05 24.9 0.1 8.2 6 1 1 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EPE31891.1 - 2e-14 53.1 43.6 8e-06 25.5 1.3 7.7 1 1 6 8 8 8 8 Leucine rich repeat LRR_9 PF14580.6 EPE31891.1 - 0.005 16.3 19.9 0.1 12.1 0.2 4.7 1 1 3 4 4 4 4 Leucine-rich repeat Cupin_6 PF12852.7 EPE31892.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Cupin SET PF00856.28 EPE31893.1 - 1e-14 55.3 0.4 1e-13 52.0 0.4 2.6 1 1 0 1 1 1 1 SET domain AWS PF17907.1 EPE31893.1 - 2.5e-05 24.2 7.9 2.5e-05 24.2 7.9 2.4 2 0 0 2 2 2 1 AWS domain Mito_carr PF00153.27 EPE31894.1 - 2.5e-70 232.5 2.1 1.3e-22 79.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EPE31894.1 - 0.016 14.4 1.8 2.1 7.5 0.0 3.0 2 1 1 3 3 3 0 Gammaproteobacterial serine protease Gyro_capsid PF04162.12 EPE31896.1 - 0.043 12.3 0.0 0.046 12.2 0.0 1.0 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) Zn_clus PF00172.18 EPE31897.1 - 0.25 11.5 12.4 0.71 10.1 12.4 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PRP21_like_P PF12230.8 EPE31898.1 - 1.4e-55 188.5 18.1 5.3e-55 186.6 18.1 1.8 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EPE31898.1 - 2.3e-36 123.5 2.1 1.2e-18 66.9 0.1 2.7 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 EPE31898.1 - 0.00067 19.2 0.3 0.0016 18.0 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger RE_BstXI PF09552.10 EPE31898.1 - 0.051 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 BstXI restriction endonuclease zf-WRNIP1_ubi PF18279.1 EPE31898.1 - 5.6 7.9 8.1 0.13 12.9 1.6 1.8 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Sec2p PF06428.11 EPE31899.1 - 8.3e-29 99.4 20.9 8.3e-29 99.4 20.9 3.0 3 1 0 3 3 3 1 GDP/GTP exchange factor Sec2p CC2-LZ PF16516.5 EPE31899.1 - 0.11 12.8 23.3 1.9 8.9 9.4 2.9 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF5401 PF17380.2 EPE31899.1 - 0.18 9.9 13.9 0.3 9.1 13.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF3584 PF12128.8 EPE31899.1 - 0.62 7.5 20.2 0.9 7.0 20.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Peptidase_S46 PF10459.9 EPE31899.1 - 1.4 7.5 8.0 2.2 6.8 8.0 1.3 1 0 0 1 1 1 0 Peptidase S46 UBA_e1_thiolCys PF10585.9 EPE31899.1 - 1.9 8.3 8.1 3.9 7.3 8.1 1.5 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site DUF2138 PF09909.9 EPE31900.1 - 0.11 10.7 0.2 0.2 9.9 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) Ribosomal_L21e PF01157.18 EPE31901.1 - 7.4e-35 118.8 5.3 7.7e-35 118.8 2.8 1.9 1 1 1 2 2 2 1 Ribosomal protein L21e DUF5486 PF17588.2 EPE31901.1 - 0.099 12.5 3.6 0.48 10.3 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5486) S4 PF01479.25 EPE31902.1 - 1.3e-11 44.0 1.1 1.3e-11 44.0 1.1 2.1 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 EPE31902.1 - 0.00057 20.7 0.5 0.0016 19.3 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Slu7 PF11708.8 EPE31903.1 - 1.4e-79 267.7 22.1 2e-78 263.9 22.1 2.4 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EPE31903.1 - 0.039 13.7 0.5 0.069 12.9 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Cript PF10235.9 EPE31903.1 - 0.34 11.5 3.4 11 6.7 0.6 2.7 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT DNA_pol_B PF00136.21 EPE31904.1 - 1.3e-102 343.9 0.0 1.8e-102 343.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EPE31904.1 - 6.2e-23 81.5 0.1 2.7e-13 49.8 0.0 2.6 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EPE31904.1 - 2.2e-18 66.5 5.2 2.2e-18 66.5 5.2 2.3 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DUF1744 PF08490.12 EPE31904.1 - 0.12 11.0 0.0 0.2 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) NAD_binding_10 PF13460.6 EPE31905.1 - 0.00043 20.2 0.0 0.00057 19.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding HsbA PF12296.8 EPE31906.1 - 5.2e-13 49.5 4.2 1e-12 48.5 4.2 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Ureidogly_lyase PF04115.12 EPE31906.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Ureidoglycolate lyase MFS_1 PF07690.16 EPE31907.1 - 7e-30 104.1 42.4 7e-30 104.1 42.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily FSH1 PF03959.13 EPE31908.1 - 4.9e-24 85.2 0.1 3.4e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Zn_clus PF00172.18 EPE31909.1 - 0.00046 20.3 8.4 0.00046 20.3 8.4 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 EPE31910.1 - 1.1e-76 257.8 0.2 2.6e-76 256.5 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EPE31910.1 - 9.5e-61 204.8 0.1 9.5e-61 204.8 0.1 1.9 2 0 0 2 2 1 1 KR domain Acyl_transf_1 PF00698.21 EPE31910.1 - 3.7e-50 171.2 0.5 6.3e-50 170.5 0.5 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EPE31910.1 - 2.2e-38 132.2 0.0 3.6e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EPE31910.1 - 2.5e-34 117.8 0.2 7.8e-34 116.2 0.1 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EPE31910.1 - 1.6e-15 57.1 0.3 9e-14 51.4 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 EPE31910.1 - 4.1e-14 53.8 0.0 3.6e-13 50.7 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPE31910.1 - 9.8e-14 51.5 0.0 4e-13 49.5 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EPE31910.1 - 1.2e-12 48.3 0.0 1.6e-11 44.6 0.0 3.0 2 1 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension adh_short_C2 PF13561.6 EPE31910.1 - 6.6e-10 38.9 0.0 2e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 EPE31910.1 - 1e-07 32.2 0.0 3.4e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 EPE31910.1 - 3.5e-05 23.7 0.2 0.0001 22.2 0.2 1.7 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_N PF00108.23 EPE31910.1 - 5.6e-05 22.6 0.1 0.00019 20.9 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Sacchrp_dh_NADP PF03435.18 EPE31910.1 - 0.0014 18.9 0.0 0.0052 17.0 0.0 2.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ADH_N PF08240.12 EPE31910.1 - 0.0021 17.9 0.1 0.0058 16.5 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_12 PF08242.12 EPE31910.1 - 0.0027 18.4 0.0 0.011 16.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE31910.1 - 0.011 16.4 0.0 0.038 14.7 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EPE31910.1 - 0.014 15.2 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.21 EPE31910.1 - 0.047 13.2 0.0 0.14 11.6 0.0 1.9 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.6 EPE31910.1 - 0.062 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain 3Beta_HSD PF01073.19 EPE31910.1 - 0.11 11.4 0.0 0.32 9.9 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family ELFV_dehydrog PF00208.21 EPE31910.1 - 0.19 11.4 1.2 13 5.5 0.0 3.0 3 0 0 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HET PF06985.11 EPE31911.1 - 6.2e-33 114.2 0.6 1.2e-32 113.3 0.6 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PKD_2 PF16407.5 EPE31911.1 - 0.21 11.8 0.3 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 PKD-like family MMM1 PF10296.9 EPE31912.1 - 6.4e-06 25.4 0.1 1.1e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Spore_YhaL PF14147.6 EPE31912.1 - 0.27 10.9 0.6 0.79 9.5 0.3 2.0 2 0 0 2 2 2 0 Sporulation protein YhaL ANTH PF07651.16 EPE31913.1 - 3.5e-81 272.2 0.0 3.5e-81 272.2 0.0 2.9 3 1 1 4 4 4 1 ANTH domain I_LWEQ PF01608.17 EPE31913.1 - 1.3e-54 184.6 6.6 1.3e-54 184.6 6.6 6.7 3 2 3 6 6 6 3 I/LWEQ domain MATalpha_HMGbox PF04769.12 EPE31914.1 - 1.1e-39 135.8 0.0 1.6e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box VanY PF02557.17 EPE31915.1 - 0.12 12.2 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase HMG_box PF00505.19 EPE31916.1 - 1e-16 61.1 0.2 1.7e-16 60.4 0.2 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box DUF2462 PF09495.10 EPE31916.1 - 0.13 13.0 1.2 0.29 11.9 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) DUF1921 PF09081.10 EPE31916.1 - 0.16 12.2 1.0 0.35 11.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1921) Alg14 PF08660.11 EPE31916.1 - 0.16 11.9 0.0 21 5.0 0.0 2.2 2 0 0 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like Exo_endo_phos PF03372.23 EPE31917.1 - 4.4e-11 42.8 0.0 6.8e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EPE31917.1 - 0.00017 21.6 1.0 0.00037 20.5 1.0 1.6 1 0 0 1 1 1 1 GRF zinc finger CDC27 PF09507.10 EPE31917.1 - 0.032 13.6 0.9 0.049 13.0 0.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Exo_endo_phos_2 PF14529.6 EPE31917.1 - 0.13 12.1 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase COX6A PF02046.15 EPE31918.1 - 1.1e-52 177.2 2.5 1.4e-52 176.9 2.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa WPP PF13943.6 EPE31918.1 - 0.09 13.2 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 WPP domain IspA PF04279.15 EPE31918.1 - 0.13 12.4 0.5 0.17 12.0 0.5 1.1 1 0 0 1 1 1 0 Intracellular septation protein A ANAPC5 PF12862.7 EPE31919.1 - 3.8e-34 116.6 3.4 3.8e-34 116.6 3.4 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 EPE31919.1 - 0.003 17.4 0.7 0.21 11.5 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPE31919.1 - 2 9.5 4.8 25 6.0 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat CIA30 PF08547.12 EPE31922.1 - 3.9e-44 150.5 0.0 4.8e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) RRM_1 PF00076.22 EPE31923.1 - 1.4e-29 101.7 0.3 2.9e-15 55.9 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPE31923.1 - 0.0016 18.5 0.1 0.042 14.0 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 EPE31923.1 - 0.0052 16.6 0.0 0.017 15.0 0.0 1.9 1 1 0 1 1 1 1 Occluded RNA-recognition motif UPF0139 PF03669.13 EPE31925.1 - 1.5e-06 27.9 0.2 1.7e-05 24.6 0.1 2.0 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0139) Med12 PF09497.10 EPE31926.1 - 2.8e-27 94.8 0.4 9e-27 93.2 0.4 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 EPE31926.1 - 0.0024 16.8 0.0 0.0041 16.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain RhoGAP PF00620.27 EPE31927.1 - 5e-49 166.0 0.0 2.5e-48 163.7 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 EPE31927.1 - 6e-12 45.7 0.5 6e-12 45.7 0.5 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RapA_C PF12137.8 EPE31927.1 - 0.004 16.2 0.1 0.0096 15.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal OmpH PF03938.14 EPE31927.1 - 0.065 13.6 9.1 1.6 9.1 5.3 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 EPE31927.1 - 1.5 8.1 6.9 2.5 7.4 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Zn_clus PF00172.18 EPE31928.1 - 7.1e-10 38.8 14.0 1.1e-09 38.2 14.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE31928.1 - 2.7e-07 29.8 0.6 3.7e-07 29.3 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SAICAR_synt PF01259.18 EPE31929.1 - 4.8e-96 321.2 0.0 5.7e-96 321.0 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase SSF PF00474.17 EPE31930.1 - 0.048 12.5 34.2 0.42 9.4 34.2 2.1 1 1 0 1 1 1 0 Sodium:solute symporter family SUI1 PF01253.22 EPE31931.1 - 1.2e-27 96.2 3.9 1.6e-27 95.8 3.9 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 EPE31931.1 - 0.12 12.6 0.3 0.18 12.0 0.3 1.2 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain EOS1 PF12326.8 EPE31932.1 - 9e-16 58.3 7.5 9e-16 58.3 7.5 1.8 2 0 0 2 2 2 1 N-glycosylation protein Tim44 PF04280.15 EPE31933.1 - 2.5e-08 34.1 0.2 3.6e-08 33.6 0.2 1.2 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 EPE31933.1 - 2.9e-05 23.2 0.0 0.00069 18.7 0.0 2.0 2 0 0 2 2 2 1 MBA1-like protein DUF3719 PF12516.8 EPE31933.1 - 0.13 12.0 0.1 0.9 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) Yae1_N PF09811.9 EPE31934.1 - 1.8e-14 53.2 1.6 3.3e-14 52.3 1.6 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Chitin_bind_1 PF00187.19 EPE31935.1 - 0.049 14.1 5.3 0.049 14.1 5.3 2.2 2 0 0 2 2 2 0 Chitin recognition protein Glyoxal_oxid_N PF07250.11 EPE31936.1 - 7.3e-42 143.2 0.0 4.7e-41 140.6 0.0 2.2 1 1 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EPE31936.1 - 5.5e-26 90.7 0.8 1.3e-25 89.5 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.19 EPE31936.1 - 8.9e-11 42.1 39.0 8.5e-09 35.7 24.0 2.5 2 0 0 2 2 2 2 Chitin recognition protein Annexin PF00191.20 EPE31937.1 - 1.8e-13 50.4 1.2 0.0047 17.0 0.0 4.3 4 0 0 4 4 4 3 Annexin DUF2235 PF09994.9 EPE31938.1 - 3.6e-85 285.8 0.0 5.2e-85 285.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) CAP PF00188.26 EPE31938.1 - 0.019 15.8 0.4 0.036 14.9 0.4 1.5 1 0 0 1 1 1 0 Cysteine-rich secretory protein family DUF2570 PF10828.8 EPE31938.1 - 0.16 11.8 0.0 0.42 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Endonuc-FokI_C PF09254.11 EPE31939.1 - 0.037 13.3 0.7 0.056 12.7 0.2 1.4 1 1 1 2 2 2 0 Restriction endonuclease FokI, C terminal CFEM PF05730.11 EPE31940.1 - 1.4e-10 41.1 9.6 2.2e-10 40.5 9.6 1.3 1 0 0 1 1 1 1 CFEM domain adh_short PF00106.25 EPE31941.1 - 1.5e-11 44.1 0.1 1e-10 41.4 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE31941.1 - 2.5e-09 37.1 0.0 8.4e-09 35.3 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CrgA PF06781.12 EPE31943.1 - 0.011 15.8 0.2 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 Cell division protein CrgA m04gp34like PF12216.8 EPE31943.1 - 0.14 11.7 0.1 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 Immune evasion protein DUF4366 PF14283.6 EPE31943.1 - 0.15 12.1 0.0 9.9 6.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Aldo_ket_red PF00248.21 EPE31945.1 - 2.8e-49 167.9 0.1 2.9e-47 161.3 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family RCC1 PF00415.18 EPE31946.1 - 1.2e-51 173.1 3.0 1.4e-08 35.2 0.1 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EPE31946.1 - 3.9e-29 99.8 28.5 8.4e-08 31.8 0.5 6.6 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat sCache_3_2 PF17203.4 EPE31946.1 - 0.086 13.0 0.0 7 6.8 0.0 2.8 2 0 0 2 2 2 0 Single cache domain 3 Acyl-CoA_dh_1 PF00441.24 EPE31947.1 - 3.6e-30 105.2 3.0 4.9e-30 104.7 3.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EPE31947.1 - 1.6e-23 83.5 0.0 7.3e-23 81.4 0.0 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EPE31947.1 - 3e-23 81.8 0.2 6.3e-23 80.8 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EPE31947.1 - 0.059 13.6 0.3 0.1 12.9 0.3 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain FAD_binding_4 PF01565.23 EPE31948.1 - 7.4e-18 64.6 0.1 1.8e-17 63.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain ACPS PF01648.20 EPE31951.1 - 1.2e-06 28.6 0.0 7.4e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF4198 PF10670.9 EPE31951.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4198) MIP PF00230.20 EPE31952.1 - 7.7e-49 166.4 7.2 9.6e-49 166.1 7.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein Fer4_12 PF13353.6 EPE31953.1 - 0.00063 20.0 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.21 EPE31953.1 - 0.02 15.3 0.0 0.033 14.6 0.0 1.5 1 0 0 1 1 1 0 Radical SAM superfamily Fer4_14 PF13394.6 EPE31953.1 - 0.035 14.3 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain NmrA PF05368.13 EPE31954.1 - 5.9e-35 120.9 0.1 8.2e-35 120.4 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE31954.1 - 7.7e-20 71.5 0.0 9.2e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE31954.1 - 1.8e-05 24.3 0.0 7.8e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EPE31954.1 - 0.00062 20.0 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EPE31954.1 - 0.0081 16.3 0.2 0.017 15.3 0.2 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EPE31954.1 - 0.059 13.8 0.1 0.11 13.0 0.1 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF3842 PF12953.7 EPE31954.1 - 0.12 12.8 0.2 0.19 12.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) F420_oxidored PF03807.17 EPE31954.1 - 0.17 12.5 0.5 0.48 11.0 0.1 2.0 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent EI24 PF07264.11 EPE31955.1 - 4.6e-15 56.3 4.3 7.5e-15 55.6 4.3 1.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) adh_short PF00106.25 EPE31958.1 - 2.6e-41 141.3 0.0 3.4e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE31958.1 - 7.6e-27 94.4 0.0 9.8e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EPE31958.1 - 7.5e-05 22.7 0.1 0.00014 21.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 EPE31958.1 - 0.0016 18.4 0.1 0.0031 17.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.10 EPE31958.1 - 0.0017 18.3 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE31958.1 - 0.0031 17.0 0.0 0.0085 15.6 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EPE31958.1 - 0.0033 16.8 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 EPE31958.1 - 0.008 15.8 0.1 0.051 13.1 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family TrkA_N PF02254.18 EPE31958.1 - 0.031 14.5 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DUF3431 PF11913.8 EPE31960.1 - 1.9e-10 40.9 0.0 3.7e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) PARP_regulatory PF01358.18 EPE31960.1 - 0.056 12.4 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit Glyco_hydro_59 PF02057.15 EPE31962.1 - 9.3e-19 67.7 3.4 1.4e-18 67.2 3.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 EPE31962.1 - 1.5e-17 64.2 5.3 5.7e-16 59.1 0.2 2.2 1 1 1 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 EPE31962.1 - 1.3e-12 47.7 3.6 4.5e-12 46.0 3.6 2.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_30 PF02055.16 EPE31962.1 - 3.6e-08 32.8 0.5 8.8e-08 31.5 0.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain ADH_zinc_N PF00107.26 EPE31964.1 - 9.8e-14 51.4 0.6 4.5e-13 49.3 0.6 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE31964.1 - 1.2e-05 25.1 0.0 0.0028 17.5 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 EPE31964.1 - 0.00042 19.9 0.1 0.00057 19.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.6 EPE31964.1 - 0.0013 19.8 0.0 0.0021 19.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 EPE31964.1 - 0.019 14.1 0.1 0.028 13.5 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 EPE31964.1 - 0.042 13.2 0.1 0.087 12.2 0.1 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.16 EPE31965.1 - 1.2e-47 162.6 49.9 1e-46 159.5 48.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily MtrF PF09472.10 EPE31965.1 - 0.034 13.5 0.1 0.034 13.5 0.1 3.0 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF2985 PF11204.8 EPE31966.1 - 5.2e-23 81.0 3.7 9.4e-23 80.2 3.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) DUF1682 PF07946.14 EPE31966.1 - 6.4 5.9 5.7 5.5 6.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Ctr PF04145.15 EPE31967.1 - 1.4e-41 142.5 0.3 2.3e-41 141.9 0.3 1.3 1 0 0 1 1 1 1 Ctr copper transporter family DUF3328 PF11807.8 EPE31969.1 - 5.9e-43 147.2 5.4 6.8e-43 147.0 5.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) SNAPc_SNAP43 PF09808.9 EPE31969.1 - 0.099 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Dioxygenase_C PF00775.21 EPE31970.1 - 0.00044 19.7 0.0 0.00085 18.8 0.0 1.5 1 0 0 1 1 1 1 Dioxygenase CAP59_mtransfer PF11735.8 EPE31972.1 - 6.3e-05 22.8 0.0 8e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CAP59_mtransfer PF11735.8 EPE31973.1 - 1.8e-57 194.8 0.0 2.1e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 EGF_2 PF07974.13 EPE31974.1 - 0.91 10.0 8.4 1.8 9.0 8.4 1.5 1 0 0 1 1 1 0 EGF-like domain BTB PF00651.31 EPE31975.1 - 1.1e-07 32.0 0.0 1.9e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TFIIF_alpha PF05793.12 EPE31975.1 - 4.6 5.7 5.4 6.2 5.3 5.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sec66 PF09802.9 EPE31976.1 - 8.6e-46 155.8 0.5 1.1e-45 155.4 0.5 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Ribosomal_S14 PF00253.21 EPE31979.1 - 3.5e-21 74.7 0.5 3.5e-21 74.7 0.5 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e TPR_2 PF07719.17 EPE31981.1 - 1.7e-07 30.8 15.2 0.0018 18.2 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EPE31981.1 - 5.3e-06 27.0 18.0 0.038 14.6 0.2 5.7 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EPE31981.1 - 0.00012 21.8 14.9 0.01 15.7 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EPE31981.1 - 0.0004 20.0 11.3 0.066 12.9 0.1 5.0 6 0 0 6 6 6 2 TPR repeat TPR_12 PF13424.6 EPE31981.1 - 0.0011 19.2 7.6 0.057 13.7 1.6 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EPE31981.1 - 0.0038 17.2 3.0 3.8 7.7 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPE31981.1 - 0.013 16.3 8.9 24 6.1 0.1 5.2 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE31981.1 - 0.034 14.4 1.0 2.6 8.4 0.3 3.4 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EPE31981.1 - 0.47 10.8 14.1 1.1 9.6 0.0 5.3 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPE31981.1 - 2.1 8.4 4.4 63 3.6 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EPE31981.1 - 2.2 8.9 11.4 2.1 8.9 0.1 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF1996 PF09362.10 EPE31982.1 - 2.2e-18 67.1 0.0 2.7e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.10 EPE31983.1 - 0.0027 17.8 2.7 0.0039 17.2 2.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) BTB_2 PF02214.22 EPE31984.1 - 2.5e-07 30.9 0.0 6.1e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EPE31984.1 - 4.7e-05 23.6 0.0 8.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Epimerase PF01370.21 EPE31987.1 - 1.3e-11 44.5 0.0 2.1e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE31987.1 - 4.2e-08 32.5 0.0 6.4e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EPE31987.1 - 1.1e-05 25.1 0.2 1.8e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EPE31987.1 - 6.1e-05 22.3 0.0 9.4e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EPE31987.1 - 0.0026 17.7 0.6 0.0077 16.1 0.5 2.3 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EPE31987.1 - 0.0036 16.5 0.1 0.047 12.9 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 EPE31987.1 - 0.0049 16.8 0.1 0.0095 15.9 0.1 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EPE31987.1 - 0.0065 15.9 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EPE31987.1 - 0.051 12.7 0.1 2 7.5 0.0 2.4 2 0 0 2 2 2 0 RmlD substrate binding domain DUF1996 PF09362.10 EPE31988.1 - 6.6e-82 275.0 4.4 8.6e-82 274.6 4.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SET PF00856.28 EPE31989.1 - 6.1e-10 39.7 0.1 3e-09 37.5 0.1 2.1 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EPE31989.1 - 1.9 8.7 7.5 0.73 10.0 3.9 2.1 2 0 0 2 2 2 0 MYND finger SET PF00856.28 EPE31990.1 - 3.4e-09 37.3 0.0 7.5e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EPE31990.1 - 1.1e-07 31.8 12.6 1.1e-07 31.8 12.6 2.0 2 0 0 2 2 2 1 MYND finger Tcf25 PF04910.14 EPE31990.1 - 0.019 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 Aldedh PF00171.22 EPE31991.1 - 1.6e-136 455.5 0.0 2e-136 455.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family COesterase PF00135.28 EPE31992.1 - 2.6e-75 254.2 0.0 3.8e-73 247.1 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE31992.1 - 1e-06 28.8 0.0 5e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Sugar_tr PF00083.24 EPE31993.1 - 1.1e-115 387.1 26.6 1.2e-115 386.9 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE31993.1 - 2.4e-19 69.5 59.5 8.3e-16 57.8 30.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily RBB1NT PF08169.11 EPE31994.1 - 0.17 12.0 0.3 0.56 10.4 0.3 1.9 1 0 0 1 1 1 0 RBB1NT (NUC162) domain Peptidase_S8 PF00082.22 EPE31995.1 - 7.1e-22 78.0 0.1 1.6e-21 76.9 0.1 1.5 1 0 0 1 1 1 1 Subtilase family CAP_N PF01213.19 EPE31995.1 - 0.044 13.3 4.9 8.3 5.8 3.8 2.7 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal zf-nanos PF05741.13 EPE31996.1 - 0.15 12.3 0.7 22 5.4 0.1 3.2 2 1 0 2 2 2 0 Nanos RNA binding domain Amidohydro_2 PF04909.14 EPE31998.1 - 5.1e-26 92.1 0.0 9e-26 91.3 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase zf-RanBP PF00641.18 EPE31999.1 - 0.0003 20.1 2.1 0.00055 19.2 2.1 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others FHA PF00498.26 EPE32000.1 - 2.7e-16 59.7 0.0 5.7e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EPE32000.1 - 0.0026 18.1 0.0 0.0071 16.6 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 EPE32000.1 - 0.051 13.1 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 YhfZ C-terminal domain DUF2570 PF10828.8 EPE32000.1 - 1.9 8.4 4.0 2 8.3 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) CdvA PF18822.1 EPE32000.1 - 1.9 8.3 8.3 2.3 8.1 0.8 2.6 2 0 0 2 2 2 0 CdvA-like coiled-coil domain FUSC PF04632.12 EPE32000.1 - 3.5 6.1 4.0 3.3 6.1 0.1 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family CASP_C PF08172.12 EPE32000.1 - 4.1 6.7 12.2 0.52 9.6 7.2 1.9 2 0 0 2 2 2 0 CASP C terminal Romo1 PF10247.9 EPE32001.1 - 7.5e-28 96.7 15.0 9.7e-28 96.3 15.0 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 EPE32001.1 - 0.0013 19.1 4.8 0.0017 18.7 4.8 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family LapA_dom PF06305.11 EPE32001.1 - 0.37 10.6 2.4 4.7 7.1 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain WD40 PF00400.32 EPE32003.1 - 1.9e-11 44.3 7.3 0.01 16.7 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat PALB2_WD40 PF16756.5 EPE32003.1 - 0.024 13.6 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 EPE32003.1 - 0.029 13.0 3.7 4.3 5.9 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 MFS_1 PF07690.16 EPE32005.1 - 1.9e-36 125.7 35.7 5e-36 124.3 35.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE32005.1 - 9.6e-11 41.2 10.5 9.6e-11 41.2 10.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Vac7 PF12751.7 EPE32005.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 adh_short PF00106.25 EPE32006.1 - 6.9e-22 77.9 0.0 9.4e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE32006.1 - 1.7e-20 73.6 0.0 2.2e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE32006.1 - 1e-06 28.8 0.0 1.3e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EPE32006.1 - 0.0018 18.2 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE32006.1 - 0.018 14.5 0.0 0.041 13.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ABM PF03992.16 EPE32007.1 - 0.0091 16.1 0.0 0.027 14.6 0.0 1.8 1 1 1 2 2 2 1 Antibiotic biosynthesis monooxygenase zf-RING_2 PF13639.6 EPE32008.1 - 2.4e-06 27.8 10.0 2.4e-06 27.8 10.0 3.2 3 1 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 EPE32008.1 - 3e-05 24.2 6.8 3e-05 24.2 6.8 2.5 3 1 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EPE32008.1 - 6.6e-05 22.8 6.1 6.6e-05 22.8 6.1 2.8 4 0 0 4 4 4 1 zinc-RING finger domain zf-RING_11 PF17123.5 EPE32008.1 - 0.00011 21.9 4.1 0.00011 21.9 4.1 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EPE32008.1 - 0.00019 21.2 5.0 0.00019 21.2 5.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE32008.1 - 0.00077 19.2 2.3 0.00077 19.2 2.3 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EPE32008.1 - 0.0089 15.6 2.6 0.0089 15.6 2.6 2.6 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-HC5HC2H PF13771.6 EPE32008.1 - 0.023 14.9 0.3 0.023 14.9 0.3 2.6 3 0 0 3 3 3 0 PHD-like zinc-binding domain Tmpp129 PF10272.9 EPE32008.1 - 0.31 10.3 5.7 0.6 9.4 5.7 1.4 1 0 0 1 1 1 0 Putative transmembrane protein precursor FANCL_C PF11793.8 EPE32008.1 - 0.39 10.9 4.7 1.4 9.2 4.7 2.0 1 0 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 EPE32008.1 - 0.71 10.0 14.0 0.048 13.7 6.6 2.6 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Abhydrolase_3 PF07859.13 EPE32009.1 - 7.6e-12 45.5 0.0 4.8e-10 39.7 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE32009.1 - 7.9e-07 29.9 0.0 9.9e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE32009.1 - 8.4e-05 21.9 0.0 0.004 16.4 0.0 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EPE32009.1 - 0.00056 19.4 0.1 0.01 15.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2235 PF09994.9 EPE32009.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DLH PF01738.18 EPE32009.1 - 0.027 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 EPE32009.1 - 0.096 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_2 PF02230.16 EPE32009.1 - 0.096 12.5 0.0 17 5.2 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 EPE32009.1 - 0.17 11.4 0.0 3.5 7.1 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF829 PF05705.14 EPE32012.1 - 1.4e-37 129.9 0.0 1.7e-37 129.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) FAM25 PF15825.5 EPE32012.1 - 0.12 12.7 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 FAM25 family DUF4188 PF13826.6 EPE32013.1 - 2.5e-25 89.1 0.1 3.6e-25 88.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 EPE32013.1 - 1.1e-05 25.1 0.7 1.5e-05 24.6 0.7 1.2 1 0 0 1 1 1 1 Haem-containing dehydratase Pyr_redox_2 PF07992.14 EPE32015.1 - 2.4e-14 53.3 0.0 3e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE32015.1 - 7.5e-06 25.4 0.0 0.057 12.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPE32015.1 - 9e-06 25.8 1.1 0.093 12.7 0.0 3.5 4 0 0 4 4 4 2 FAD-NAD(P)-binding GIDA PF01134.22 EPE32015.1 - 2.5e-05 23.5 1.4 0.1 11.7 0.1 2.4 2 1 1 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.14 EPE32015.1 - 0.00012 21.0 0.1 0.0062 15.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EPE32015.1 - 0.00094 18.9 1.3 0.27 10.7 0.4 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPE32015.1 - 0.008 15.3 0.4 0.019 14.1 0.0 1.8 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 EPE32015.1 - 0.029 13.6 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HA70_C PF17993.1 EPE32015.1 - 0.03 14.4 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Haemagglutinin 70 C-terminal domain NAD_binding_8 PF13450.6 EPE32015.1 - 0.036 14.3 0.1 0.074 13.3 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPE32015.1 - 0.045 12.8 0.7 0.21 10.6 0.4 1.9 1 1 1 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 EPE32015.1 - 0.052 12.8 0.4 0.17 11.1 0.1 1.9 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 EPE32015.1 - 0.06 12.6 0.4 0.66 9.2 0.0 2.2 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 EPE32015.1 - 0.2 10.7 0.3 11 5.0 0.0 2.3 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) SLATT_fungal PF18142.1 EPE32016.1 - 1.2e-25 89.8 0.0 2e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain DUF4231 PF14015.6 EPE32016.1 - 0.15 12.5 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Ninjurin PF04923.12 EPE32016.1 - 0.18 11.8 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 Ninjurin RdRP_5 PF07925.11 EPE32016.1 - 0.23 8.8 0.1 0.28 8.5 0.1 1.0 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 F-box PF00646.33 EPE32017.1 - 0.00066 19.5 2.2 0.0015 18.4 2.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPE32017.1 - 0.13 12.2 3.9 0.33 10.9 3.9 1.7 1 0 0 1 1 1 0 F-box-like Caleosin PF05042.13 EPE32018.1 - 1.7e-81 272.1 0.1 2.3e-81 271.7 0.1 1.2 1 0 0 1 1 1 1 Caleosin related protein Vsr PF03852.15 EPE32019.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr p450 PF00067.22 EPE32020.1 - 7.5e-60 203.0 0.0 1e-59 202.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 EPE32021.1 - 9.1e-07 28.9 0.0 4.8e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE32021.1 - 2.6e-05 24.0 0.1 4.1e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CorA PF01544.18 EPE32023.1 - 2.7e-05 23.7 1.6 7.6e-05 22.2 0.3 2.3 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Phage_holin_3_6 PF07332.11 EPE32023.1 - 0.12 12.5 6.4 8.5 6.5 6.3 2.3 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III CitMHS PF03600.16 EPE32023.1 - 0.14 11.3 3.7 0.21 10.8 3.7 1.2 1 0 0 1 1 1 0 Citrate transporter DUF676 PF05057.14 EPE32024.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 EPE32024.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF726 PF05277.12 EPE32024.1 - 0.17 10.8 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) p450 PF00067.22 EPE32026.1 - 3.4e-44 151.4 0.0 4.4e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 EPE32027.1 - 2e-23 82.7 0.7 3e-23 82.1 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE32027.1 - 4.3e-07 29.9 0.0 1.1e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_A4 PF01828.17 EPE32028.1 - 8.6e-15 54.8 2.0 1.2e-14 54.3 2.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_A4 PF01828.17 EPE32029.1 - 9.2e-06 25.3 3.1 1.3e-05 24.8 3.1 1.2 1 0 0 1 1 1 1 Peptidase A4 family Ntox25 PF15530.6 EPE32029.1 - 0.019 15.1 0.1 0.03 14.5 0.1 1.2 1 0 0 1 1 1 0 Bacterial toxin 25 Peptidase_A4 PF01828.17 EPE32030.1 - 4e-29 101.6 0.1 4.9e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF1223 PF06764.11 EPE32031.1 - 3.6e-55 187.1 0.0 4.4e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1223) Rrp40_N PF18311.1 EPE32032.1 - 5.8e-19 67.8 2.9 9.8e-19 67.0 1.3 2.2 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 EPE32032.1 - 1.5e-16 60.4 0.0 3e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 KH domain DUF3991 PF13154.6 EPE32032.1 - 0.03 14.7 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3991) HSP70 PF00012.20 EPE32033.1 - 2.9e-78 263.6 3.8 4.6e-78 262.9 3.8 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EPE32033.1 - 5.5e-09 35.3 0.2 8.3e-09 34.7 0.2 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Glyco_hydro_7 PF00840.20 EPE32034.1 - 1.5e-198 659.9 19.9 1.7e-198 659.7 19.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 NIPSNAP PF07978.13 EPE32037.1 - 1.4e-39 134.4 0.1 1.7e-28 98.8 0.0 2.3 2 0 0 2 2 2 2 NIPSNAP NifQ PF04891.12 EPE32037.1 - 0.14 12.5 0.1 0.68 10.3 0.0 1.9 2 0 0 2 2 2 0 NifQ Rogdi_lz PF10259.9 EPE32038.1 - 5.8e-77 258.8 0.0 6.5e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rpp20 PF12328.8 EPE32039.1 - 7.6e-31 106.9 2.1 3.4e-30 104.8 2.1 1.8 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EPE32039.1 - 3e-15 55.8 0.0 4.5e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Alba Iron_traffic PF04362.14 EPE32042.1 - 0.0072 16.0 0.2 0.036 13.8 0.1 2.0 2 1 0 2 2 2 1 Bacterial Fe(2+) trafficking Macoilin PF09726.9 EPE32042.1 - 2.8 6.4 13.3 3.7 6.0 13.3 1.1 1 0 0 1 1 1 0 Macoilin family Zn_clus PF00172.18 EPE32044.1 - 0.00024 21.2 7.5 0.00041 20.4 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE32044.1 - 0.026 13.3 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain SBP56 PF05694.11 EPE32045.1 - 1.8e-06 27.0 0.0 0.0015 17.4 0.0 2.4 2 1 0 2 2 2 2 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 EPE32045.1 - 0.023 14.0 0.1 2.9 7.0 0.1 2.6 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller NHL PF01436.21 EPE32045.1 - 0.077 13.1 0.0 7 6.9 0.0 3.1 2 0 0 2 2 2 0 NHL repeat TP_methylase PF00590.20 EPE32046.1 - 8.6e-45 153.3 0.1 2e-44 152.1 0.0 1.7 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EPE32046.1 - 2.5e-12 47.2 0.0 7.7e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 EPE32046.1 - 6.2e-11 41.5 0.2 6.2e-11 41.5 0.2 1.9 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 EPE32046.1 - 1.2e-10 40.9 0.1 8.6e-08 31.7 0.1 2.3 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal DASH_Spc19 PF08287.11 EPE32047.1 - 6.5e-48 162.6 1.6 9.2e-48 162.1 1.6 1.2 1 0 0 1 1 1 1 Spc19 HET PF06985.11 EPE32048.1 - 3.1e-31 108.7 2.0 2.7e-30 105.6 2.0 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Eryth_link_C PF16915.5 EPE32048.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Annelid erythrocruorin linker subunit C-terminus F-box-like PF12937.7 EPE32049.1 - 0.0032 17.3 0.6 0.019 14.8 0.8 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EPE32049.1 - 0.013 15.4 0.6 0.028 14.3 0.6 1.6 1 0 0 1 1 1 0 F-box domain Urate_ox_N PF06181.11 EPE32049.1 - 0.2 10.9 0.0 0.3 10.4 0.0 1.1 1 0 0 1 1 1 0 Urate oxidase N-terminal DUF3176 PF11374.8 EPE32050.1 - 7.7e-35 119.3 0.7 1.9e-34 118.0 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) MFS_1 PF07690.16 EPE32051.1 - 9.6e-49 166.2 52.4 3.9e-46 157.6 50.5 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EPE32051.1 - 0.0056 15.6 31.7 0.13 11.1 14.8 2.3 2 0 0 2 2 2 2 MFS_1 like family Rsm22 PF09243.10 EPE32052.1 - 1.7e-31 109.5 0.0 1.7e-29 103.0 0.0 3.0 2 1 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Fungal_trans_2 PF11951.8 EPE32052.1 - 1.4e-05 24.1 0.6 2.6e-05 23.2 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE32052.1 - 1.8e-05 24.8 9.7 1.8e-05 24.8 9.7 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_deac_1 PF01522.21 EPE32053.1 - 2.6e-18 66.1 0.0 3.5e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase PGM_PMM_I PF02878.16 EPE32053.1 - 0.023 14.4 0.3 7.5 6.3 0.1 2.4 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DUF4145 PF13643.6 EPE32053.1 - 0.23 11.6 0.1 2.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) HET PF06985.11 EPE32054.1 - 5e-32 111.3 0.2 1.5e-31 109.7 0.2 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3029 PF11230.8 EPE32054.1 - 0.044 12.1 0.0 0.076 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) Amidohydro_3 PF07969.11 EPE32056.1 - 6.1e-65 220.5 0.0 7.6e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EPE32056.1 - 1.4e-07 31.1 0.1 2.8e-06 26.9 0.0 2.5 3 0 0 3 3 3 1 Amidohydrolase family 2OG-FeII_Oxy_3 PF13640.6 EPE32057.1 - 4.5e-10 40.3 0.0 2.2e-09 38.1 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SIR2 PF02146.17 EPE32058.1 - 7.2e-56 188.9 0.0 1.2e-55 188.2 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EPE32058.1 - 0.001 18.8 0.0 0.0027 17.4 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fmp27_WPPW PF10359.9 EPE32058.1 - 0.19 10.5 3.9 0.28 10.0 3.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Aurora-A_bind PF09041.10 EPE32059.1 - 0.0037 17.3 0.1 0.017 15.2 0.0 2.1 2 0 0 2 2 2 1 Aurora-A binding NifU PF01106.17 EPE32059.1 - 0.079 13.1 2.3 0.37 11.0 0.3 2.8 3 0 0 3 3 3 0 NifU-like domain TauD PF02668.16 EPE32060.1 - 1.8e-30 106.7 0.0 2.5e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EPE32060.1 - 1.4e-05 24.4 0.0 2.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 CsiD HET PF06985.11 EPE32061.1 - 8.6e-28 97.5 1.0 7.2e-27 94.5 1.0 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) C166 PF17615.2 EPE32062.1 - 1.1e-30 106.9 10.3 1.7e-30 106.3 10.3 1.2 1 0 0 1 1 1 1 Family of unknown function Pkinase PF00069.25 EPE32063.1 - 4.7e-09 36.0 0.0 8.3e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE32063.1 - 0.017 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.14 EPE32063.1 - 0.042 13.2 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPE32063.1 - 0.047 13.6 0.3 1.6 8.6 0.4 2.4 1 1 0 2 2 2 0 Phosphotransferase enzyme family F1F0-ATPsyn_F PF10791.9 EPE32064.1 - 0.028 14.9 0.2 0.057 13.9 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi PhaP_Bmeg PF09602.10 EPE32064.1 - 0.073 13.0 0.3 0.42 10.5 0.2 2.1 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) NmrA PF05368.13 EPE32065.1 - 5.9e-26 91.5 0.0 7.3e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE32065.1 - 3.8e-16 59.5 0.2 6.8e-16 58.7 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE32065.1 - 0.00017 21.1 0.3 0.0015 18.1 0.2 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE32065.1 - 0.0097 14.9 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EPE32065.1 - 0.014 14.9 0.1 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPE32065.1 - 0.067 12.3 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Male sterility protein Bestrophin PF01062.21 EPE32066.1 - 4.8e-28 98.4 0.1 6.2e-28 98.0 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Inhibitor_I36 PF03995.13 EPE32067.1 - 0.0039 17.1 5.2 0.0077 16.1 5.2 1.5 1 0 0 1 1 1 1 Peptidase inhibitor family I36 ATP-sulfurylase PF01747.17 EPE32068.1 - 6.7e-88 293.7 0.0 9.6e-88 293.2 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 EPE32068.1 - 5.4e-55 185.6 0.1 8.2e-55 185.0 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 EPE32068.1 - 2.2e-53 180.2 0.0 3.5e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Complex1_LYR PF05347.15 EPE32069.1 - 2.8e-21 75.3 4.1 3.7e-21 74.9 4.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EPE32069.1 - 1.5e-08 35.3 3.3 1.7e-08 35.1 3.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EPE32069.1 - 0.01 16.4 1.1 0.014 16.0 1.0 1.4 1 1 0 1 1 1 0 Complex1_LYR-like DUF4653 PF15546.6 EPE32070.1 - 3 7.4 16.6 0.033 13.8 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4653) Hydrolase PF00702.26 EPE32071.1 - 1.3e-17 64.8 0.9 1.8e-17 64.3 0.9 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EPE32071.1 - 1e-16 61.9 0.0 1.4e-16 61.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EPE32071.1 - 5.8e-08 32.8 0.7 4.8e-07 29.8 0.2 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EPE32071.1 - 1.6e-06 28.4 0.4 8.4e-05 22.7 0.4 2.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EPE32071.1 - 0.0013 18.2 0.0 0.061 12.7 0.0 2.1 2 0 0 2 2 2 1 Putative Phosphatase DUF705 PF05152.12 EPE32071.1 - 0.023 14.2 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Acid_PPase PF12689.7 EPE32071.1 - 0.2 11.5 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase PAPS_reduct PF01507.19 EPE32072.1 - 9.2e-41 139.8 0.0 1.4e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF3494 PF11999.8 EPE32073.1 - 1.7e-46 158.5 18.6 1.7e-46 158.5 18.6 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3494) DUF2457 PF10446.9 EPE32073.1 - 1.4 8.0 6.9 0.26 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) baeRF_family10 PF18854.1 EPE32074.1 - 0.1 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 HET PF06985.11 EPE32075.1 - 7.8e-13 49.0 6.0 1.2e-10 41.9 1.3 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Peptidase_M28 PF04389.17 EPE32076.1 - 6.8e-41 140.1 0.1 1e-40 139.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EPE32076.1 - 6.1e-12 45.4 3.2 1.1e-11 44.6 1.4 2.3 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EPE32076.1 - 5.4e-05 23.0 0.0 0.00012 21.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EPE32076.1 - 0.0024 16.9 0.0 0.025 13.6 0.0 2.0 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase F-box-like PF12937.7 EPE32077.1 - 0.002 18.0 1.4 0.0032 17.3 0.3 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EPE32077.1 - 0.014 15.3 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 F-box domain p450 PF00067.22 EPE32078.1 - 5.6e-66 223.2 0.0 7.2e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3712 PF12505.8 EPE32079.1 - 1.9e-29 102.5 1.0 1.9e-29 102.5 1.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) Microvir_J PF04726.13 EPE32079.1 - 0.17 11.8 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Microvirus J protein Heme_oxygenase PF01126.20 EPE32080.1 - 0.016 15.0 0.2 0.023 14.5 0.2 1.3 1 1 0 1 1 1 0 Heme oxygenase ApoLp-III PF07464.11 EPE32080.1 - 0.024 14.7 0.7 0.054 13.6 0.1 1.7 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Transcrip_act PF04949.13 EPE32080.1 - 0.095 12.6 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Transcriptional activator F-box-like PF12937.7 EPE32081.1 - 0.00061 19.6 0.2 0.00061 19.6 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 EPE32082.1 - 0.014 15.3 0.3 0.035 14.0 0.1 1.9 2 0 0 2 2 2 0 F-box-like Methyltransf_25 PF13649.6 EPE32083.1 - 0.00013 22.6 0.0 0.00024 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE32083.1 - 0.0038 17.8 0.0 0.0071 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE32083.1 - 0.0042 16.9 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE32083.1 - 0.027 15.2 0.0 0.046 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain APH PF01636.23 EPE32084.1 - 5.5e-05 23.2 0.0 0.00032 20.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE32084.1 - 0.00015 21.5 0.0 0.00042 20.0 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Glyco_hydro_76 PF03663.14 EPE32084.1 - 0.059 12.9 0.1 0.086 12.3 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 76 gag-asp_proteas PF13975.6 EPE32085.1 - 3.2e-05 24.4 0.0 0.026 15.1 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EPE32085.1 - 0.00026 21.6 0.2 0.0029 18.2 0.1 2.3 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.10 EPE32085.1 - 0.00027 20.7 0.1 0.063 13.1 0.0 2.2 1 1 1 2 2 2 2 Aspartyl protease BRE1 PF08647.11 EPE32085.1 - 1.4 9.0 7.1 1.1 9.4 0.3 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase CopD PF05425.13 EPE32086.1 - 3.6 8.0 8.7 0.58 10.6 2.6 2.3 2 0 0 2 2 2 0 Copper resistance protein D Hydrolase_6 PF13344.6 EPE32087.1 - 3.6e-28 97.6 0.0 8.2e-28 96.5 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPE32087.1 - 3e-19 68.9 0.3 8.2e-19 67.5 0.1 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EPE32087.1 - 4.1e-07 30.5 0.1 0.076 13.3 0.0 3.8 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EPE32087.1 - 0.0012 19.0 0.0 2.1 8.4 0.0 3.1 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EPE32087.1 - 0.14 12.6 0.0 5.9 7.2 0.0 2.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EPE32087.1 - 0.22 11.2 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HET PF06985.11 EPE32089.1 - 7.3e-36 123.7 0.0 1.2e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 EPE32090.1 - 6.4e-33 114.2 0.1 1.5e-32 113.0 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AXE1 PF05448.12 EPE32091.1 - 1.1e-12 47.3 0.0 3.6e-10 39.0 0.0 2.9 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 EPE32091.1 - 3.2e-09 37.7 0.7 4e-09 37.4 0.7 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EPE32091.1 - 3.2e-07 30.2 0.0 4.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EPE32091.1 - 9.6e-07 28.7 0.1 3.6e-06 26.8 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPE32091.1 - 1.1e-06 28.3 0.3 3.2e-06 26.8 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EPE32091.1 - 3.3e-06 26.6 0.1 1.7e-05 24.2 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 EPE32091.1 - 0.00031 20.4 0.0 0.00059 19.5 0.0 1.6 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 EPE32091.1 - 0.00091 19.2 0.0 0.0021 18.0 0.0 1.5 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Inhibitor_I36 PF03995.13 EPE32092.1 - 0.9 9.5 3.9 0.58 10.1 0.2 2.5 3 0 0 3 3 3 0 Peptidase inhibitor family I36 DUF3328 PF11807.8 EPE32096.1 - 9.9e-08 32.0 0.1 1.4e-07 31.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) p450 PF00067.22 EPE32097.1 - 3.8e-36 124.8 0.0 1.5e-31 109.7 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Tyrosinase PF00264.20 EPE32098.1 - 2.3e-46 158.9 0.2 3.5e-46 158.3 0.2 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase zf-CCCH PF00642.24 EPE32099.1 - 4.7e-13 48.7 15.0 5.5e-08 32.5 1.4 4.1 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) IBR PF01485.21 EPE32099.1 - 1.6e-10 41.1 42.9 3.2e-07 30.4 9.8 3.9 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Torus PF16131.5 EPE32099.1 - 6.2e-10 39.7 6.0 0.00025 21.7 0.1 3.2 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 EPE32099.1 - 3e-08 33.5 31.7 2e-06 27.7 6.3 3.9 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_4 PF18044.1 EPE32099.1 - 3.7e-07 29.8 3.8 3.7e-07 29.8 3.8 4.7 7 0 0 7 7 7 2 CCCH-type zinc finger zf-C3HC4_3 PF13920.6 EPE32099.1 - 0.0028 17.5 5.8 0.0028 17.5 5.8 5.1 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE32099.1 - 0.0034 17.2 10.4 0.0034 17.2 10.4 4.0 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE32099.1 - 0.007 16.4 11.7 0.007 16.4 11.7 3.9 3 2 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 EPE32099.1 - 0.013 15.8 8.7 0.013 15.8 8.7 4.0 3 0 0 3 3 3 0 Ring finger domain zf-His_Me_endon PF05551.11 EPE32101.1 - 6.9e-11 42.5 3.3 1.1e-10 41.9 3.3 1.2 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease Rpn9_C PF18261.1 EPE32101.1 - 0.23 11.1 0.3 0.23 11.1 0.3 1.8 2 0 0 2 2 2 0 Rpn9 C-terminal helix F-box-like PF12937.7 EPE32103.1 - 9.4e-08 31.8 2.0 9.4e-08 31.8 2.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EPE32103.1 - 0.00022 21.0 0.1 0.023 14.6 0.0 3.2 3 0 0 3 3 3 1 F-box domain SIP1 PF04938.12 EPE32104.1 - 7.2e-08 32.4 0.0 3.4e-06 26.9 0.0 2.8 2 2 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) WRW PF10206.9 EPE32104.1 - 2.7 8.4 6.5 44 4.5 4.0 2.3 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f Megourin PF17560.2 EPE32105.1 - 0.29 11.4 1.9 0.58 10.4 1.9 1.5 1 0 0 1 1 1 0 Aphid Megourins Amidohydro_2 PF04909.14 EPE32108.1 - 1.3e-28 100.6 0.7 1.7e-28 100.2 0.7 1.1 1 0 0 1 1 1 1 Amidohydrolase ketoacyl-synt PF00109.26 EPE32109.1 - 6.7e-71 238.8 0.0 1.6e-70 237.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EPE32109.1 - 3.1e-42 145.0 9.6 2.7e-41 141.9 0.0 3.6 3 1 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EPE32109.1 - 5.7e-42 144.3 0.0 9.8e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE32109.1 - 1.5e-34 118.5 0.3 3.2e-34 117.5 0.3 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EPE32109.1 - 2.8e-25 89.8 0.0 2.5e-24 86.7 0.0 2.5 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 EPE32109.1 - 1.2e-20 73.6 2.4 9.7e-11 41.9 0.3 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 EPE32109.1 - 2.2e-16 60.0 0.0 4.5e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.7 EPE32109.1 - 0.00048 20.8 1.8 0.00048 20.8 1.8 4.4 3 1 3 6 6 6 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 EPE32109.1 - 0.00054 20.4 0.0 0.0018 18.7 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EPE32109.1 - 0.027 13.9 0.4 0.074 12.4 0.1 1.8 2 0 0 2 2 2 0 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EPE32109.1 - 0.046 13.6 0.2 2 8.3 0.1 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Podoplanin PF05808.11 EPE32110.1 - 0.0003 20.9 2.6 0.00051 20.2 2.6 1.4 1 0 0 1 1 1 1 Podoplanin DUF4366 PF14283.6 EPE32110.1 - 0.028 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF5301 PF17225.3 EPE32110.1 - 0.04 14.3 0.2 0.11 13.0 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5300) FMN_bind PF04205.14 EPE32110.1 - 0.088 13.4 3.6 0.24 12.0 3.6 1.7 1 0 0 1 1 1 0 FMN-binding domain MGC-24 PF05283.11 EPE32110.1 - 0.21 12.1 2.9 0.33 11.4 2.9 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 EPE32110.1 - 8.8 6.3 23.4 19 5.3 23.4 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein BTB PF00651.31 EPE32112.1 - 0.0019 18.4 0.1 0.0063 16.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BIRC6 PF12356.8 EPE32112.1 - 0.042 13.3 0.3 0.089 12.2 0.3 1.5 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 Glyco_hydro_11 PF00457.17 EPE32113.1 - 2.5e-71 239.0 14.6 2.8e-71 238.8 14.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Peptidase_C25_C PF03785.14 EPE32113.1 - 0.073 12.9 0.3 0.24 11.3 0.1 1.9 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain MFS_1 PF07690.16 EPE32114.1 - 1.9e-45 155.3 26.8 1.9e-45 155.3 26.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily BTB PF00651.31 EPE32115.1 - 3.9e-13 49.6 0.0 6.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PCI PF01399.27 EPE32116.1 - 3.2e-21 75.8 0.1 1.4e-20 73.8 0.0 2.1 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EPE32116.1 - 2.9e-15 56.1 0.3 7.5e-15 54.8 0.3 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF2935 PF11155.8 EPE32116.1 - 0.015 15.6 0.4 0.54 10.6 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) HhH-GPD PF00730.25 EPE32116.1 - 0.038 14.4 1.2 13 6.3 0.1 2.9 3 1 0 3 3 3 0 HhH-GPD superfamily base excision DNA repair protein Gag_p30 PF02093.16 EPE32116.1 - 0.066 12.7 0.3 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Gag P30 core shell protein FSH1 PF03959.13 EPE32117.1 - 4.8e-57 193.1 0.0 6.3e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Cys_Met_Meta_PP PF01053.20 EPE32119.1 - 8.1e-23 80.6 0.0 1.1e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EPE32119.1 - 1e-05 24.9 0.0 2e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II FMO-like PF00743.19 EPE32120.1 - 4.8e-15 55.0 0.1 1.3e-14 53.6 0.1 1.6 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EPE32120.1 - 1.3e-10 41.4 0.0 4.3e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE32120.1 - 6.3e-08 32.6 0.0 3.3e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE32120.1 - 1.5e-06 27.6 0.0 4.3e-06 26.2 0.0 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE32120.1 - 0.00011 21.5 0.6 0.00074 18.9 0.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPE32120.1 - 0.0015 17.8 0.1 0.0083 15.3 0.0 2.0 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EPE32120.1 - 0.0019 17.5 0.2 0.005 16.1 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 EPE32120.1 - 0.02 14.9 0.1 0.39 10.7 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding MFS_1 PF07690.16 EPE32121.1 - 7.9e-25 87.5 25.1 7.9e-25 87.5 25.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 EPE32121.1 - 0.0019 18.5 0.1 0.0019 18.5 0.1 3.6 2 2 2 4 4 4 1 Domain of unknown function (DUF1772) UPF0093 PF03653.13 EPE32121.1 - 0.057 13.6 0.9 0.25 11.6 0.0 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0093) Avidin PF01382.17 EPE32121.1 - 0.063 13.8 0.2 0.14 12.6 0.2 1.5 1 0 0 1 1 1 0 Avidin family Phage_T4_gp19 PF06841.12 EPE32121.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 T4-like virus tail tube protein gp19 MFS_1 PF07690.16 EPE32122.1 - 8.5e-30 103.9 28.5 4.1e-29 101.6 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Bac_luciferase PF00296.20 EPE32123.1 - 4.5e-60 203.7 0.0 6.3e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Amidohydro_2 PF04909.14 EPE32123.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase PAN_3 PF08277.12 EPE32124.1 - 0.021 14.7 0.9 0.051 13.4 0.9 1.6 1 0 0 1 1 1 0 PAN-like domain PAN_4 PF14295.6 EPE32124.1 - 0.024 14.5 0.4 0.055 13.4 0.4 1.6 1 0 0 1 1 1 0 PAN domain PAN_1 PF00024.26 EPE32124.1 - 0.039 13.9 0.5 0.088 12.8 0.5 1.6 1 0 0 1 1 1 0 PAN domain adh_short PF00106.25 EPE32125.1 - 4.1e-14 52.5 0.0 5.3e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE32125.1 - 1.4e-08 34.6 0.0 1.7e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE32125.1 - 3e-06 27.3 0.0 1.6e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EPE32125.1 - 0.0044 16.2 0.0 0.0067 15.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EPE32125.1 - 0.0051 16.3 0.0 0.0064 16.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE32125.1 - 0.11 11.8 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase LIAS_N PF16881.5 EPE32126.1 - 2.5e-21 76.1 0.0 5.5e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EPE32126.1 - 1.1e-13 51.9 0.0 2.2e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily ERG2_Sigma1R PF04622.12 EPE32127.1 - 3.3e-96 320.6 0.6 4e-96 320.4 0.6 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DUF3850 PF12961.7 EPE32127.1 - 0.17 12.0 0.0 6.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3850) DUF4360 PF14273.6 EPE32128.1 - 2.7e-61 206.6 3.2 3.4e-61 206.2 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) adh_short PF00106.25 EPE32129.1 - 4.8e-31 107.7 0.0 2.2e-29 102.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE32129.1 - 1.3e-22 80.5 0.0 7.5e-21 74.8 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE32129.1 - 4.9e-05 23.3 0.0 0.0014 18.5 0.0 2.1 2 0 0 2 2 2 1 KR domain CorA PF01544.18 EPE32131.1 - 1.1e-06 28.2 0.3 6.2e-06 25.7 0.3 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Abhydrolase_3 PF07859.13 EPE32132.1 - 9e-28 97.6 0.0 1.2e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EPE32132.1 - 3.8e-13 49.1 0.0 7e-13 48.2 0.0 1.4 2 0 0 2 2 2 1 Steryl acetyl hydrolase DUF2974 PF11187.8 EPE32132.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF4238 PF14022.6 EPE32133.1 - 7.7e-59 199.4 0.0 1.3e-58 198.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) ketoacyl-synt PF00109.26 EPE32134.1 - 1.4e-81 273.8 0.0 2.7e-81 272.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EPE32134.1 - 9.2e-66 222.5 0.0 1.5e-65 221.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EPE32134.1 - 8.5e-56 188.7 0.0 1.8e-55 187.6 0.0 1.6 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.22 EPE32134.1 - 1.4e-38 131.5 1.5 3.6e-38 130.2 0.9 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EPE32134.1 - 6.5e-12 45.6 0.0 1.4e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EPE32134.1 - 9.7e-12 45.3 0.0 2.4e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EPE32134.1 - 1.2e-09 37.9 0.1 0.0002 20.7 0.1 2.3 2 0 0 2 2 2 2 Polyketide synthase dehydratase Thiolase_N PF00108.23 EPE32134.1 - 0.00026 20.5 0.0 0.00063 19.2 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain FAD_binding_3 PF01494.19 EPE32135.1 - 1.6e-16 60.5 5.6 6.6e-15 55.2 5.6 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EPE32135.1 - 0.00017 21.7 0.6 0.00044 20.4 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EPE32135.1 - 0.00026 21.0 0.0 0.00057 19.9 0.0 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.10 EPE32135.1 - 0.00038 19.6 0.0 0.0026 16.9 0.0 2.1 1 1 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 EPE32135.1 - 0.00053 19.3 0.3 0.0018 17.6 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE32135.1 - 0.0058 16.3 4.4 0.0059 16.2 2.1 2.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EPE32135.1 - 0.037 14.6 0.7 0.37 11.4 0.7 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ACP_syn_III_C PF08541.10 EPE32135.1 - 0.13 12.4 0.4 19 5.5 0.4 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Tyrosinase PF00264.20 EPE32136.1 - 5.6e-41 141.3 0.0 1.3e-40 140.1 0.0 1.6 2 1 0 2 2 2 1 Common central domain of tyrosinase MFS_1 PF07690.16 EPE32137.1 - 8.9e-41 140.0 57.5 1.7e-40 139.1 46.4 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EPE32137.1 - 0.00087 17.7 7.3 0.00087 17.7 7.3 2.6 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family HscB_4_cys PF18256.1 EPE32137.1 - 0.15 11.9 1.2 0.26 11.1 1.2 1.4 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif CytB6-F_Fe-S PF08802.10 EPE32139.1 - 0.13 12.3 0.4 6.4 6.9 0.0 3.2 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit Clathrin_propel PF01394.20 EPE32140.1 - 0.025 14.9 0.1 0.053 13.9 0.1 1.6 1 0 0 1 1 1 0 Clathrin propeller repeat zf-C2H2 PF00096.26 EPE32140.1 - 0.056 13.9 0.8 0.097 13.2 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 EPE32140.1 - 0.42 10.4 2.8 0.79 9.5 2.8 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain HET PF06985.11 EPE32141.1 - 6.9e-18 65.4 0.0 1.3e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Chitin_bind_1 PF00187.19 EPE32143.1 - 9.8e-05 22.7 15.8 0.00019 21.8 15.7 1.6 1 1 0 1 1 1 1 Chitin recognition protein NMO PF03060.15 EPE32144.1 - 1.2e-34 120.2 2.6 1e-25 90.8 0.4 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 EPE32144.1 - 1.9e-10 40.3 0.0 8.2e-05 21.8 0.5 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EPE32144.1 - 6.2e-08 32.0 1.9 9.3e-08 31.5 1.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EPE32144.1 - 1.4e-07 31.0 0.2 2e-07 30.5 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NAD_binding_1 PF00175.21 EPE32145.1 - 1.4e-10 41.8 0.0 2.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Globin PF00042.22 EPE32145.1 - 6.6e-09 36.3 0.0 1.2e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Globin Protoglobin PF11563.8 EPE32145.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 EPE32145.1 - 0.016 15.3 1.0 1.2 9.3 0.1 3.1 2 1 0 3 3 3 0 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EPE32145.1 - 0.048 13.8 0.0 0.093 12.8 0.0 1.6 1 0 0 1 1 1 0 FAD-binding domain DUF2315 PF10231.9 EPE32145.1 - 0.1 12.7 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 Apoptogenic protein 1 ATP_bind_3 PF01171.20 EPE32145.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Zn_clus PF00172.18 EPE32146.1 - 8.7e-11 41.8 9.2 1.7e-10 40.9 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE32146.1 - 0.0021 17.2 0.3 0.0059 15.7 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EPE32147.1 - 1.5e-43 149.1 30.8 1.5e-43 149.1 30.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE32147.1 - 7.7e-16 58.0 6.3 7.7e-16 58.0 6.3 2.7 1 1 3 4 4 4 1 Sugar (and other) transporter Saf_2TM PF18303.1 EPE32147.1 - 0.087 12.4 1.7 0.75 9.4 0.0 2.9 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain DHHC PF01529.20 EPE32147.1 - 4.2 7.5 5.4 15 5.7 0.1 3.1 2 1 0 3 3 3 0 DHHC palmitoyltransferase Cutinase PF01083.22 EPE32148.1 - 4.3e-32 111.5 4.1 6.9e-32 110.8 4.1 1.3 1 0 0 1 1 1 1 Cutinase MSA-2c PF12238.8 EPE32148.1 - 1.3 9.0 3.7 2.4 8.1 3.7 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c ADH_zinc_N PF00107.26 EPE32149.1 - 1.6e-10 41.1 0.8 2.4e-10 40.5 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE32149.1 - 6.3e-08 32.5 0.6 4.3e-07 29.8 0.5 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain SM-ATX PF14438.6 EPE32149.1 - 0.13 12.4 0.0 0.38 10.9 0.0 1.7 1 1 0 1 1 1 0 Ataxin 2 SM domain RNA_pol_Rpc4 PF05132.14 EPE32150.1 - 3.5 8.1 11.0 7.8 6.9 1.6 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF4470 PF14737.6 EPE32151.1 - 5.4e-22 77.8 0.0 1.1e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) HsbA PF12296.8 EPE32152.1 - 0.098 13.1 2.3 4 7.9 0.4 3.3 3 0 0 3 3 3 0 Hydrophobic surface binding protein A TolA_bind_tri PF16331.5 EPE32152.1 - 0.34 11.0 14.4 0.037 14.1 2.0 3.2 2 0 0 2 2 2 0 TolA binding protein trimerisation SMBP PF16785.5 EPE32152.1 - 0.59 10.4 5.1 2 8.7 5.1 1.9 1 0 0 1 1 1 0 Small metal-binding protein ThylakoidFormat PF11264.8 EPE32153.1 - 0.031 14.0 0.2 0.057 13.1 0.2 1.4 1 0 0 1 1 1 0 Thylakoid formation protein Flavi_M PF01004.19 EPE32153.1 - 0.21 11.4 1.4 2.5 7.9 0.9 2.2 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M AAA_11 PF13086.6 EPE32156.1 - 8.2e-12 45.5 0.0 1.4e-10 41.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPE32156.1 - 1.6e-06 28.5 0.0 2.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPE32156.1 - 4.5e-06 26.5 0.0 5.6e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EPE32156.1 - 5.1e-05 23.0 0.0 0.0001 22.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 EPE32156.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 EPE32156.1 - 0.094 13.0 0.1 0.33 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EPE32156.1 - 0.095 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EPE32156.1 - 0.18 11.6 0.2 0.36 10.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Esterase PF00756.20 EPE32159.1 - 0.015 14.9 0.2 0.066 12.8 0.2 1.8 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 EPE32159.1 - 0.024 14.1 0.3 0.062 12.8 0.3 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EPE32159.1 - 0.13 12.1 0.3 0.46 10.2 0.2 1.9 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Glyco_hydro_35 PF01301.19 EPE32160.1 - 1.3e-85 287.8 1.1 1.7e-85 287.4 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 EPE32160.1 - 7.5e-09 35.4 0.4 3.9e-08 33.0 0.4 1.9 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 EPE32160.1 - 7.7e-07 29.7 0.3 4.6e-06 27.2 0.0 2.4 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Glyoxalase PF00903.25 EPE32160.1 - 0.0066 16.6 0.1 0.64 10.2 0.0 2.3 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3158 PF11358.8 EPE32161.1 - 0.00086 19.1 0.5 0.0017 18.2 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3158) DUF4618 PF15397.6 EPE32161.1 - 0.0014 18.1 2.3 0.0024 17.4 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Frankia_peptide PF14407.6 EPE32161.1 - 0.022 14.7 0.6 1.2 9.2 0.3 2.6 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Zn-ribbon_8 PF09723.10 EPE32161.1 - 0.022 14.8 4.5 0.53 10.5 0.9 2.8 2 0 0 2 2 2 0 Zinc ribbon domain NACHT_N PF17100.5 EPE32161.1 - 0.022 14.6 1.5 0.097 12.5 1.2 2.0 2 1 0 2 2 2 0 N-terminal domain of NWD NACHT-NTPase Swm2 PF17083.5 EPE32161.1 - 0.089 12.8 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Nucleolar protein Swm2 TipAS PF07739.13 EPE32161.1 - 0.15 12.6 1.8 2.3 8.8 0.2 2.4 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain DUF2390 PF09523.10 EPE32161.1 - 0.48 10.8 5.7 6.8 7.1 0.6 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2390) zf-RING_7 PF02591.15 EPE32161.1 - 0.66 10.2 5.4 18 5.6 1.0 3.2 3 0 0 3 3 3 0 C4-type zinc ribbon domain Apolipoprotein PF01442.18 EPE32161.1 - 1.3 8.9 9.8 0.25 11.2 6.1 1.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Ogr_Delta PF04606.12 EPE32161.1 - 1.9 8.5 5.3 18 5.4 0.4 3.0 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger V-ATPase_G_2 PF16999.5 EPE32161.1 - 5.1 7.6 9.5 1.6 9.2 4.8 2.2 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit AAA_11 PF13086.6 EPE32162.1 - 1.3e-22 80.8 0.0 2.6e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EPE32162.1 - 3.7e-15 56.1 0.0 7.2e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPE32162.1 - 2.2e-07 31.3 0.0 2.8e-06 27.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain zf-CCCH_4 PF18044.1 EPE32162.1 - 4.6e-05 23.1 4.2 8.3e-05 22.3 4.2 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger AAA_30 PF13604.6 EPE32162.1 - 8e-05 22.4 0.1 0.002 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EPE32162.1 - 0.0024 17.1 0.0 0.0062 15.8 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EPE32162.1 - 0.0046 17.0 0.0 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCCH PF00642.24 EPE32162.1 - 0.0048 16.8 3.5 0.009 15.9 3.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mg_chelatase PF01078.21 EPE32162.1 - 0.044 13.2 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EPE32162.1 - 0.07 12.7 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain zf-CCCH_2 PF14608.6 EPE32162.1 - 0.071 13.6 2.4 0.23 12.0 2.4 1.8 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PhoH PF02562.16 EPE32162.1 - 0.081 12.4 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.29 EPE32162.1 - 0.16 12.4 0.8 0.93 9.9 0.7 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf_CCCH_4 PF18345.1 EPE32162.1 - 0.28 11.3 4.8 0.59 10.3 4.8 1.6 1 0 0 1 1 1 0 Zinc finger domain p450 PF00067.22 EPE32163.1 - 2.4e-55 188.1 0.0 3.1e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.12 EPE32164.1 - 6.3e-20 71.1 0.0 1.2e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE32164.1 - 4.2e-09 36.5 0.0 1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPE32164.1 - 0.00029 20.2 0.1 0.00062 19.1 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 EPE32164.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 EPE32164.1 - 0.0043 16.9 0.2 0.0043 16.9 0.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated FAD_binding_2 PF00890.24 EPE32164.1 - 0.0055 15.8 0.1 0.0085 15.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EPE32164.1 - 0.038 12.7 0.1 0.051 12.3 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_114 PF03537.13 EPE32165.1 - 1e-84 283.5 0.1 1.2e-84 283.2 0.1 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Glyco_hydro_31 PF01055.26 EPE32167.1 - 4.9e-152 507.1 6.4 6.1e-152 506.8 6.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EPE32167.1 - 9.9e-42 141.8 0.0 6e-41 139.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EPE32167.1 - 1e-13 51.4 0.5 2.8e-13 50.0 0.5 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like DUF1522 PF07482.11 EPE32167.1 - 0.4 11.0 2.2 0.94 9.8 2.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1522) Lipoxygenase PF00305.19 EPE32168.1 - 1.5e-22 79.8 0.1 2.5e-22 79.1 0.1 1.3 1 1 0 1 1 1 1 Lipoxygenase FaeA PF04703.12 EPE32168.1 - 0.0041 17.5 0.2 1.3 9.4 0.0 2.4 2 0 0 2 2 2 2 FaeA-like protein RTA1 PF04479.13 EPE32169.1 - 6e-66 222.0 12.6 6e-66 222.0 12.6 1.4 2 0 0 2 2 2 1 RTA1 like protein Caveolin PF01146.17 EPE32169.1 - 0.19 11.7 0.3 0.19 11.7 0.3 2.5 3 0 0 3 3 3 0 Caveolin dsDNA_bind PF01984.20 EPE32170.1 - 1.2e-36 125.3 6.7 1.4e-36 125.1 6.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Coq4 PF05019.13 EPE32171.1 - 5.9e-96 320.1 0.0 7.2e-96 319.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.28 EPE32172.1 - 3e-14 53.8 0.0 4.5e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 SET domain RRM_1 PF00076.22 EPE32173.1 - 0.00049 19.9 0.0 0.00092 19.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SecE PF00584.20 EPE32174.1 - 1.2e-15 57.1 0.0 1.4e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Fungal_trans_2 PF11951.8 EPE32175.1 - 0.00021 20.3 1.0 0.00021 20.3 1.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1992 PF09350.10 EPE32176.1 - 1.9e-20 72.8 0.4 5.4e-20 71.3 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) RPAP1_N PF08621.10 EPE32176.1 - 0.023 14.5 0.2 0.023 14.5 0.2 2.0 2 0 0 2 2 2 0 RPAP1-like, N-terminal Cnn_1N PF07989.11 EPE32178.1 - 1.8e-08 34.4 7.5 5.1e-08 33.0 7.5 1.9 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 Dynactin_p22 PF07426.11 EPE32178.1 - 0.45 10.4 8.2 0.06 13.2 3.2 2.1 2 0 0 2 2 2 0 Dynactin subunit p22 KxDL PF10241.9 EPE32178.1 - 0.83 10.0 5.2 4.4 7.7 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein UPF0242 PF06785.11 EPE32178.1 - 8.9 6.4 11.7 0.69 10.0 5.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Pkinase PF00069.25 EPE32179.1 - 1.7e-23 83.3 0.0 2.7e-23 82.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE32179.1 - 6.8e-08 32.1 0.1 4.5e-07 29.4 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Ricin_B_lectin PF00652.22 EPE32181.1 - 6.5e-14 52.3 0.0 0.00016 21.9 0.1 4.0 2 2 1 3 3 3 3 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EPE32181.1 - 2e-06 28.4 0.1 0.05 14.3 0.1 3.8 4 0 0 4 4 4 3 Ricin-type beta-trefoil lectin domain-like FIST_C PF10442.9 EPE32181.1 - 0.0067 16.4 0.0 2.8 7.9 0.0 2.3 2 0 0 2 2 2 2 FIST C domain DPBB_1 PF03330.18 EPE32182.1 - 1.8e-05 24.9 0.0 3.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EPE32182.1 - 0.00032 20.5 0.5 0.0006 19.6 0.5 1.4 1 0 0 1 1 1 1 Barwin family ETRAMP PF09716.10 EPE32182.1 - 2.6 8.2 5.1 6.8 6.8 5.1 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NmrA PF05368.13 EPE32183.1 - 3.6e-35 121.6 0.0 4.6e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE32183.1 - 2e-22 80.0 0.0 2.7e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE32183.1 - 5.2e-06 26.1 0.0 7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE32183.1 - 0.0053 16.2 0.0 0.0091 15.4 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EPE32183.1 - 0.038 13.0 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EPE32183.1 - 0.053 13.0 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 EPE32183.1 - 0.09 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EPE32183.1 - 0.11 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GCFC PF07842.12 EPE32184.1 - 7.8e-77 258.6 4.9 7.8e-77 258.6 4.9 1.8 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EPE32184.1 - 6.8e-13 48.3 5.5 1.4e-12 47.2 5.5 1.6 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 EPE32184.1 - 4.8e-12 46.2 10.9 4.8e-12 46.2 10.9 2.7 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 EPE32184.1 - 6.5e-08 32.6 3.1 3.7e-07 30.1 1.5 2.8 2 0 0 2 2 2 1 G-patch domain PilX PF13681.6 EPE32184.1 - 0.12 12.8 0.0 0.4 11.1 0.0 1.9 1 0 0 1 1 1 0 Type IV pilus assembly protein PilX C-term WD40 PF00400.32 EPE32185.1 - 2.6e-54 179.9 22.9 3.3e-09 37.2 0.6 8.6 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE32185.1 - 1.5e-15 57.2 0.0 4.7e-05 23.6 0.0 4.9 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPE32185.1 - 2.3e-06 26.6 0.2 0.0011 17.7 0.1 4.0 4 1 0 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EPE32185.1 - 2.1e-05 23.5 0.3 0.48 9.1 0.0 3.3 3 0 0 3 3 3 3 Nup133 N terminal like bZIP_1 PF00170.21 EPE32185.1 - 0.082 13.0 0.3 0.21 11.7 0.3 1.6 1 0 0 1 1 1 0 bZIP transcription factor HEAT PF02985.22 EPE32186.1 - 0.00012 22.0 0.1 0.6 10.5 0.1 5.1 6 0 0 6 6 5 1 HEAT repeat Cnd1 PF12717.7 EPE32186.1 - 0.00047 20.2 0.3 0.17 11.9 0.3 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EPE32186.1 - 0.00081 19.0 0.1 0.015 14.8 0.0 2.3 2 0 0 2 2 2 1 CLASP N terminal TAN PF11640.8 EPE32186.1 - 0.002 18.3 0.3 0.014 15.5 0.0 2.4 1 1 1 2 2 2 1 Telomere-length maintenance and DNA damage repair MMS19_N PF14500.6 EPE32186.1 - 0.021 14.4 1.1 0.43 10.1 0.3 3.0 2 2 2 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II GPS2_interact PF15784.5 EPE32186.1 - 0.09 13.2 2.4 0.36 11.3 2.4 2.0 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain TPR_MLP1_2 PF07926.12 EPE32186.1 - 0.21 11.7 13.7 0.21 11.6 10.7 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pil1 PF13805.6 EPE32186.1 - 0.21 11.0 7.2 0.48 9.9 7.2 1.5 1 0 0 1 1 1 0 Eisosome component PIL1 UPF0242 PF06785.11 EPE32186.1 - 0.43 10.7 3.8 1.2 9.2 3.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 EPE32186.1 - 1.9 9.0 18.2 0.47 11.0 11.1 2.9 2 1 1 3 3 3 0 Apg6 coiled-coil region RepB PF07506.11 EPE32186.1 - 2.1 8.4 9.6 0.25 11.4 2.0 3.0 2 1 1 3 3 3 0 RepB plasmid partitioning protein DUF724 PF05266.14 EPE32186.1 - 2.5 7.9 7.5 9.5 6.0 7.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 EPE32186.1 - 3.4 7.8 10.2 9.3 6.3 10.2 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 EPE32186.1 - 7 6.9 12.3 10 6.3 10.8 2.1 2 0 0 2 2 1 0 JNK_SAPK-associated protein-1 PP1_bind PF15276.6 EPE32187.1 - 4.2 7.7 11.0 0.68 10.3 2.0 3.6 2 0 0 2 2 2 0 Protein phosphatase 1 binding PH_10 PF15411.6 EPE32188.1 - 1.2e-35 122.5 0.3 6.8e-33 113.5 0.1 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain RhoGEF PF00621.20 EPE32188.1 - 8.7e-30 104.3 0.0 2.3e-29 103.0 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 EPE32188.1 - 2e-09 37.2 0.0 6e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 EPE32188.1 - 0.097 13.2 0.1 0.37 11.3 0.0 2.0 2 0 0 2 2 2 0 PH domain MbeB_N PF04837.12 EPE32188.1 - 0.12 12.7 0.2 0.12 12.7 0.2 1.9 2 0 0 2 2 2 0 MbeB-like, N-term conserved region CDC24 PF06395.11 EPE32189.1 - 8.4e-24 83.6 0.0 1.5e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin WD40 PF00400.32 EPE32190.1 - 1.4e-28 98.5 3.7 0.00055 20.7 0.1 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat F-box-like PF12937.7 EPE32190.1 - 2.1e-08 33.9 3.0 2.1e-08 33.9 1.0 2.1 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 EPE32190.1 - 5.9e-07 29.7 1.9 0.0037 17.5 0.0 3.9 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 EPE32190.1 - 0.00026 20.8 0.7 0.0024 17.7 0.2 2.3 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.8 EPE32190.1 - 0.00027 19.7 0.4 0.087 11.5 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EPE32190.1 - 0.0024 17.9 0.2 4.9 7.2 0.0 4.1 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Aa_trans PF01490.18 EPE32191.1 - 2.6e-31 108.8 20.2 4.1e-31 108.1 20.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IBR PF01485.21 EPE32192.1 - 1.8e-13 50.5 28.4 1.1e-08 35.2 2.8 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain P16-Arc PF04699.14 EPE32194.1 - 1.1e-48 165.5 0.0 1.2e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DJ-1_PfpI PF01965.24 EPE32195.1 - 6e-14 52.2 0.0 8e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Adaptin_N PF01602.20 EPE32197.1 - 4.8e-117 391.7 9.7 5.9e-117 391.4 9.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EPE32197.1 - 1.1e-43 148.1 0.0 2.3e-43 147.0 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EPE32197.1 - 4.8e-14 52.6 0.0 9.9e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EPE32197.1 - 0.033 14.2 6.0 0.78 9.8 0.2 3.2 2 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Methyltransf_11 PF08241.12 EPE32198.1 - 3.5e-10 40.4 0.0 7.1e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE32198.1 - 1e-09 38.4 0.0 1.7e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE32198.1 - 5.2e-07 30.3 0.0 1.2e-06 29.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE32198.1 - 1.5e-06 28.9 0.0 2.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE32198.1 - 0.0024 17.7 0.0 0.006 16.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE32198.1 - 0.03 13.6 0.0 0.074 12.4 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family SLATT_fungal PF18142.1 EPE32199.1 - 4.2e-25 88.1 0.4 5.3e-25 87.7 0.4 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Fungal_trans_2 PF11951.8 EPE32202.1 - 8e-06 24.9 0.4 9.6e-06 24.6 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SCP1201-deam PF14428.6 EPE32202.1 - 0.12 12.2 0.4 12 5.8 0.1 2.5 2 0 0 2 2 2 0 SCP1.201-like deaminase PALP PF00291.25 EPE32203.1 - 5.3e-59 200.0 0.5 6.4e-59 199.8 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Aminotran_1_2 PF00155.21 EPE32203.1 - 0.013 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II PRANC PF09372.10 EPE32204.1 - 0.38 11.1 3.0 0.38 11.1 0.1 2.5 3 0 0 3 3 3 0 PRANC domain HET PF06985.11 EPE32206.1 - 4.3e-26 92.0 0.0 8.4e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.23 EPE32207.1 - 2.8e-14 53.6 0.0 5.1e-14 52.8 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EPE32207.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 EPE32207.1 - 0.023 14.3 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 EPE32207.1 - 0.11 11.4 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Pox_EPC_I2-L1 PF12575.8 EPE32208.1 - 0.1 12.9 0.2 3.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 DJ-1_PfpI PF01965.24 EPE32209.1 - 2.7e-11 43.6 0.0 9.5e-11 41.8 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EPE32209.1 - 4.2e-08 33.1 0.0 1.7e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 ThiJ/PfpI family-like Sod_Fe_C PF02777.18 EPE32211.1 - 8.6e-36 122.2 0.4 8.6e-36 122.2 0.4 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EPE32211.1 - 1.1e-29 102.7 1.4 2.3e-29 101.7 1.4 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sld5 PF05916.11 EPE32212.1 - 2.7e-22 79.3 0.0 3.7e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Glyco_hydro_72 PF03198.14 EPE32215.1 - 7.6e-103 344.1 0.3 1e-102 343.6 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EPE32215.1 - 1.4e-06 27.9 0.2 0.0079 15.7 0.0 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) adh_short PF00106.25 EPE32216.1 - 7.1e-40 136.6 0.0 9.8e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE32216.1 - 3e-28 99.0 0.0 4.1e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE32216.1 - 1.2e-06 28.6 0.0 2.5e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 KR domain F-box-like PF12937.7 EPE32217.1 - 0.0021 17.9 0.6 0.02 14.8 0.1 2.8 2 1 0 2 2 2 1 F-box-like Pirin PF02678.16 EPE32219.1 - 2.4e-31 107.9 0.0 4.4e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EPE32219.1 - 6.6e-24 84.3 0.0 1.2e-22 80.2 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EPE32219.1 - 1.4e-06 27.9 0.3 9.4e-05 22.1 0.1 2.3 2 0 0 2 2 2 1 Cupin domain Abhydrolase_3 PF07859.13 EPE32223.1 - 2.2e-15 57.1 0.0 5.1e-15 55.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPE32223.1 - 3.1e-10 39.9 0.0 0.00059 19.4 0.0 2.3 2 1 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 EPE32223.1 - 8.1e-06 25.0 0.0 0.00015 20.8 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family AXE1 PF05448.12 EPE32223.1 - 2.4e-05 23.2 0.0 0.016 13.9 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.7 EPE32223.1 - 8.6e-05 21.6 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EPE32223.1 - 0.0013 17.8 0.0 0.0018 17.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase BAAT_C PF08840.11 EPE32223.1 - 0.0038 17.2 0.0 0.0094 15.9 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Say1_Mug180 PF10340.9 EPE32223.1 - 0.035 13.0 0.0 0.23 10.3 0.0 2.0 1 1 0 1 1 1 0 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EPE32223.1 - 0.074 12.3 0.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PRKCSH PF07915.13 EPE32224.1 - 1.7e-19 70.6 2.0 2.9e-19 69.9 0.1 2.4 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EPE32224.1 - 0.0064 16.2 0.2 0.065 12.9 0.2 2.3 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Sugar_tr PF00083.24 EPE32227.1 - 2.6e-77 260.6 8.4 3.3e-41 141.6 1.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EPE32227.1 - 2.4e-28 99.1 14.2 2.5e-13 49.7 0.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily ORC_WH_C PF18137.1 EPE32227.1 - 0.15 12.1 2.1 0.29 11.2 2.1 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Vfa1 PF08432.10 EPE32227.1 - 0.25 11.7 9.2 0.63 10.3 9.2 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2206 PF09971.9 EPE32227.1 - 5.6 5.6 8.2 4.6 5.9 0.4 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2206) Ank_2 PF12796.7 EPE32228.1 - 1.4e-27 96.1 0.2 7.3e-14 52.1 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE32228.1 - 2.4e-17 61.2 0.2 7.7e-07 29.0 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EPE32228.1 - 3.4e-15 56.2 0.1 9.3e-10 38.8 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EPE32228.1 - 1.1e-14 54.2 0.0 1.2e-06 28.7 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EPE32228.1 - 4.2e-13 49.3 0.2 2.7e-08 33.9 0.0 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Goodbye PF17109.5 EPE32228.1 - 0.098 13.1 0.4 0.68 10.4 0.1 2.5 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain Glyco_hydro_10 PF00331.20 EPE32229.1 - 1.2e-98 330.2 0.1 1.6e-98 329.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 EPE32229.1 - 1.3e-11 44.2 11.7 3.1e-11 43.0 11.7 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Fungal_trans_2 PF11951.8 EPE32230.1 - 6.8e-08 31.7 0.2 1.5e-07 30.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE32230.1 - 0.0034 17.5 11.8 0.0061 16.7 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPE32231.1 - 2.9e-32 112.0 57.3 1.2e-30 106.7 12.5 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Acetyltransf_8 PF13523.6 EPE32232.1 - 4.2e-44 149.7 0.0 7e-44 149.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MCU PF04678.13 EPE32234.1 - 3.1e-25 89.3 0.1 3.1e-25 89.3 0.1 2.4 3 0 0 3 3 3 1 Mitochondrial calcium uniporter RNase_J_C PF17770.1 EPE32234.1 - 0.01 16.8 3.2 0.045 14.8 0.3 2.8 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain Transket_pyr PF02779.24 EPE32235.1 - 1.6e-64 216.9 0.0 2.5e-64 216.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EPE32235.1 - 2.3e-58 197.5 0.0 3.1e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EPE32235.1 - 2.7e-57 192.7 0.1 4.3e-57 192.1 0.1 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EPE32235.1 - 2.7e-19 68.4 1.0 6.2e-19 67.3 1.0 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus BSD PF03909.17 EPE32236.1 - 1.8e-31 107.9 2.1 9.9e-15 54.3 0.1 2.8 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 EPE32236.1 - 7.3e-24 83.9 0.0 2e-23 82.5 0.0 1.8 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Pectate_lyase PF03211.13 EPE32240.1 - 3e-84 281.6 7.8 3e-84 281.6 7.8 1.6 2 0 0 2 2 2 1 Pectate lyase Presenilin PF01080.17 EPE32240.1 - 3 6.5 4.2 3.8 6.2 4.2 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 EPE32240.1 - 4.8 5.6 7.2 5.9 5.3 7.2 1.1 1 0 0 1 1 1 0 Macoilin family Catalase PF00199.19 EPE32241.1 - 1.8e-176 586.9 0.2 2.3e-176 586.5 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EPE32241.1 - 4.6e-15 55.6 0.0 8.9e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Fungal_trans PF04082.18 EPE32242.1 - 7.3e-10 38.3 2.0 1.1e-09 37.8 2.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.21 EPE32243.1 - 6.6e-141 470.2 39.1 8.1e-141 469.9 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE32243.1 - 7.6e-36 123.8 38.4 9.8e-36 123.5 38.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4360 PF14273.6 EPE32245.1 - 3.6e-16 59.5 0.2 4.5e-16 59.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF1751 PF08551.10 EPE32246.1 - 4.3e-06 27.2 0.2 7.5e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EPE32246.1 - 5.1e-05 23.3 0.8 8.8e-05 22.5 0.8 1.4 1 0 0 1 1 1 1 Rhomboid family Prenyltransf PF01255.19 EPE32247.1 - 1.9e-83 279.4 0.0 2.5e-83 279.0 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase ING PF12998.7 EPE32248.1 - 5.7e-09 36.5 0.9 0.00041 20.9 0.0 2.9 3 0 0 3 3 3 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EPE32248.1 - 8.3e-06 25.6 7.9 1.4e-05 24.9 7.9 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EPE32248.1 - 0.016 15.5 0.7 0.038 14.2 0.7 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 EPE32248.1 - 0.14 11.7 2.7 0.27 10.8 2.7 1.4 1 0 0 1 1 1 0 PHD-finger LRR_4 PF12799.7 EPE32249.1 - 0.00056 20.3 0.1 0.00056 20.3 0.1 3.9 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EPE32249.1 - 0.022 15.2 1.4 3.9 8.4 0.1 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 EPE32249.1 - 0.42 10.8 6.3 30 5.0 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat CCDC71L PF15374.6 EPE32250.1 - 0.026 13.8 3.2 0.036 13.4 3.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L NARP1 PF12569.8 EPE32250.1 - 0.25 10.2 4.4 0.35 9.7 4.4 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 U79_P34 PF03064.16 EPE32250.1 - 0.36 10.1 8.7 0.3 10.4 7.0 1.6 2 0 0 2 2 2 0 HSV U79 / HCMV P34 ADH_zinc_N PF00107.26 EPE32252.1 - 1.5e-10 41.1 0.1 3.3e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE32252.1 - 1.1e-08 34.9 0.4 2.8e-08 33.6 0.1 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2716 PF10898.8 EPE32253.1 - 0.13 12.6 0.0 0.18 12.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2716) NICE-3 PF07406.11 EPE32256.1 - 0.0073 16.3 0.4 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 NICE-3 protein DUF4129 PF13559.6 EPE32256.1 - 0.042 14.1 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Spo7 PF03907.13 EPE32256.1 - 0.048 13.1 1.3 0.077 12.5 1.3 1.3 1 0 0 1 1 1 0 Spo7-like protein DUF3431 PF11913.8 EPE32259.1 - 2.8e-10 40.3 0.0 6.3e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) DUF711 PF05167.12 EPE32259.1 - 0.011 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) Myelin_PLP PF01275.19 EPE32259.1 - 0.12 12.2 0.7 0.26 11.1 0.7 1.5 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) Fungal_trans_2 PF11951.8 EPE32260.1 - 8.7e-08 31.4 0.5 1.4e-07 30.7 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE32260.1 - 9.5e-07 28.8 8.7 1.8e-06 27.9 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPE32261.1 - 1.8e-20 73.1 25.2 1.8e-20 73.1 25.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE32261.1 - 1.6e-06 27.3 8.3 1.6e-06 27.3 8.3 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 EPE32261.1 - 9.4e-05 21.0 3.4 0.011 14.2 4.1 2.2 1 1 1 2 2 2 2 Transmembrane secretion effector HET PF06985.11 EPE32262.1 - 5.8e-25 88.3 0.0 1.8e-24 86.7 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box PF00646.33 EPE32263.1 - 0.071 13.0 0.0 0.22 11.5 0.0 1.9 1 0 0 1 1 1 0 F-box domain FAD_binding_4 PF01565.23 EPE32265.1 - 2.7e-18 66.1 0.0 5.3e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE32265.1 - 0.0057 16.7 0.6 0.014 15.4 0.6 1.6 1 0 0 1 1 1 1 Berberine and berberine like Ank_4 PF13637.6 EPE32266.1 - 3.7e-05 24.2 0.3 0.0028 18.2 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE32266.1 - 0.00018 21.7 0.1 0.03 14.6 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE32266.1 - 0.00028 21.4 0.0 0.006 17.1 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EPE32266.1 - 0.052 14.0 0.1 4.8 7.8 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat H_lectin PF09458.10 EPE32267.1 - 6.5e-30 103.1 9.8 1.6e-18 66.6 0.1 5.2 5 0 0 5 5 5 3 H-type lectin domain Peptidase_M10 PF00413.24 EPE32267.1 - 0.00093 19.1 0.5 0.0045 16.8 0.5 2.0 1 1 0 1 1 1 1 Matrixin Peptidase_M7 PF02031.16 EPE32267.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family SAPS PF04499.15 EPE32268.1 - 4.1e-196 652.5 13.7 7.2e-115 384.6 0.0 3.8 4 0 0 4 4 4 3 SIT4 phosphatase-associated protein Snf7 PF03357.21 EPE32269.1 - 4.9e-45 153.2 12.3 5.9e-45 153.0 12.3 1.0 1 0 0 1 1 1 1 Snf7 DUF1664 PF07889.12 EPE32269.1 - 0.018 15.1 7.0 1.4 9.0 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EPE32269.1 - 0.019 15.4 8.9 0.56 10.7 2.0 2.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.8 EPE32269.1 - 0.02 12.5 6.4 0.025 12.1 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Alpha-2-MRAP_C PF06401.11 EPE32269.1 - 0.025 14.6 2.3 0.057 13.4 1.6 1.8 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain RE_Bsp6I PF09504.10 EPE32269.1 - 0.04 13.5 0.1 0.073 12.7 0.1 1.5 1 0 0 1 1 1 0 Bsp6I restriction endonuclease DUF2205 PF10224.9 EPE32269.1 - 0.13 12.3 5.0 0.15 12.0 1.4 2.6 2 1 1 3 3 3 0 Short coiled-coil protein Thioredoxin_3 PF13192.6 EPE32269.1 - 0.18 11.9 0.5 0.73 9.9 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain FlaC_arch PF05377.11 EPE32269.1 - 0.22 11.9 7.9 6.9 7.2 0.0 3.6 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) TRPM_tetra PF16519.5 EPE32269.1 - 0.24 11.5 3.3 9.6 6.4 0.0 3.2 2 1 1 3 3 3 0 Tetramerisation domain of TRPM Laminin_II PF06009.12 EPE32269.1 - 0.28 11.2 5.7 3.2 7.8 1.2 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF848 PF05852.11 EPE32269.1 - 0.41 10.8 4.8 0.68 10.0 3.6 2.1 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2120 PF09893.9 EPE32269.1 - 0.49 10.5 4.5 0.3 11.2 2.3 1.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) DASH_Dam1 PF08653.10 EPE32269.1 - 1.1 9.2 3.5 30 4.5 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 HET PF06985.11 EPE32270.1 - 3e-34 118.5 0.6 3e-34 118.5 0.6 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF2529 PF10740.9 EPE32270.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) DUF1771 PF08590.10 EPE32271.1 - 5.7e-25 87.5 5.9 1.4e-24 86.2 5.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EPE32271.1 - 2.3e-10 40.7 0.2 2.3e-10 40.7 0.2 2.0 2 0 0 2 2 2 1 Smr domain Spore_YhcN_YlaJ PF09580.10 EPE32271.1 - 5.5 7.1 8.9 0.21 11.7 2.5 1.9 2 1 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF1996 PF09362.10 EPE32274.1 - 1e-65 222.1 0.2 1.5e-65 221.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 EPE32274.1 - 6.5e-18 64.7 10.3 1.6e-17 63.4 10.3 1.7 1 0 0 1 1 1 1 WSC domain Lipase_C PF18067.1 EPE32276.1 - 0.044 14.3 0.1 0.07 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipase C-terminal domain UCR_Fe-S_N PF10399.9 EPE32276.1 - 0.13 11.6 2.9 0.23 10.8 2.9 1.3 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal cobW PF02492.19 EPE32278.1 - 3.9e-43 147.1 0.1 5.2e-43 146.7 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EPE32278.1 - 5.1e-05 23.2 0.2 0.00026 20.9 0.0 2.2 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 EPE32278.1 - 0.0034 17.3 0.3 0.68 9.8 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EPE32278.1 - 0.0049 17.1 0.2 0.085 13.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EPE32278.1 - 0.019 15.0 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EPE32278.1 - 0.035 13.9 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EPE32278.1 - 0.039 13.9 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 EPE32278.1 - 0.04 13.7 0.3 0.38 10.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF463 PF04317.12 EPE32278.1 - 0.057 12.3 0.1 0.1 11.5 0.1 1.4 1 0 0 1 1 1 0 YcjX-like family, DUF463 NTPase_1 PF03266.15 EPE32278.1 - 0.11 12.4 0.1 0.38 10.6 0.0 1.9 3 0 0 3 3 3 0 NTPase F-box_4 PF15966.5 EPE32280.1 - 0.0096 15.8 0.3 0.024 14.5 0.0 1.8 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 EPE32280.1 - 0.069 13.1 0.2 3 7.8 0.1 3.3 3 0 0 3 3 3 0 F-box-like FAD_binding_4 PF01565.23 EPE32281.1 - 2.4e-23 82.4 3.3 4.4e-23 81.6 3.3 1.4 1 0 0 1 1 1 1 FAD binding domain Amidoligase_2 PF12224.8 EPE32282.1 - 3.2e-18 66.3 0.0 4.6e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme Amidoligase_2 PF12224.8 EPE32283.1 - 7.9e-07 29.0 0.0 0.0012 18.5 0.0 2.1 2 0 0 2 2 2 2 Putative amidoligase enzyme Tyrosinase PF00264.20 EPE32284.1 - 8.2e-28 98.2 1.3 2.1e-27 96.9 1.3 1.6 1 1 0 1 1 1 1 Common central domain of tyrosinase Dioxygenase_C PF00775.21 EPE32285.1 - 2.8e-08 33.4 0.0 5.6e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 Dioxygenase Pkinase PF00069.25 EPE32286.1 - 1.4e-30 106.6 0.0 1.4e-29 103.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE32286.1 - 1.8e-06 27.4 1.0 3.6e-06 26.5 0.2 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPE32286.1 - 0.091 11.5 0.3 0.13 11.0 0.3 1.2 1 0 0 1 1 1 0 Fungal protein kinase AP4E_app_platf PF14807.6 EPE32286.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Glyco_tranf_2_2 PF10111.9 EPE32290.1 - 0.00069 19.2 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EPE32290.1 - 0.0054 16.7 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Pkinase PF00069.25 EPE32291.1 - 2e-13 50.4 0.0 1.3e-12 47.7 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE32291.1 - 1.3e-06 28.0 0.0 0.0088 15.4 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Choline_kinase PF01633.20 EPE32291.1 - 0.13 11.8 0.0 0.88 9.1 0.0 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase CorA PF01544.18 EPE32292.1 - 3.2e-09 36.5 3.3 8.8e-09 35.1 3.3 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein AA_permease PF00324.21 EPE32293.1 - 5.6e-41 140.6 35.3 9.8e-41 139.8 35.3 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE32293.1 - 3.7e-20 72.2 37.9 4.9e-20 71.8 37.9 1.2 1 0 0 1 1 1 1 Amino acid permease DIOX_N PF14226.6 EPE32294.1 - 1.8e-29 102.8 0.0 3.9e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPE32294.1 - 1.2e-21 77.1 0.0 2.1e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_6 PF12697.7 EPE32295.1 - 5.2e-06 27.2 0.0 6.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE32295.1 - 0.0021 17.3 0.1 0.0043 16.4 0.1 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE32295.1 - 0.025 14.2 0.0 0.049 13.3 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Acetyltransf_3 PF13302.7 EPE32296.1 - 3.1e-21 76.5 0.0 4.2e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE32296.1 - 0.00073 19.5 0.0 0.6 10.1 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_8 PF13523.6 EPE32296.1 - 0.0037 16.9 0.2 2.3 7.9 0.0 2.9 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Aminotran_1_2 PF00155.21 EPE32297.1 - 3.7e-34 118.5 0.0 4.3e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4478 PF14793.6 EPE32297.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases Sua5_yciO_yrdC PF01300.18 EPE32297.1 - 0.13 11.7 0.0 0.34 10.4 0.0 1.6 1 1 0 1 1 1 0 Telomere recombination V_ATPase_I PF01496.19 EPE32298.1 - 0 1084.1 0.0 0 1083.9 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.21 EPE32298.1 - 0.025 14.2 4.9 5.4 6.5 3.1 2.6 2 1 0 2 2 2 0 Intermediate filament protein Baculo_PEP_C PF04513.12 EPE32298.1 - 0.055 13.5 1.7 5 7.2 0.1 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4988 PF16378.5 EPE32298.1 - 0.084 12.5 0.2 0.24 11.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function DivIC PF04977.15 EPE32298.1 - 0.13 12.1 1.0 0.53 10.1 0.3 2.5 2 0 0 2 2 2 0 Septum formation initiator FAM184 PF15665.5 EPE32298.1 - 0.18 11.5 3.8 0.28 10.9 1.2 2.0 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B CheZ PF04344.13 EPE32298.1 - 0.21 11.5 4.1 0.11 12.4 0.9 2.0 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Atg14 PF10186.9 EPE32298.1 - 0.35 9.9 1.7 0.39 9.7 0.3 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 EPE32298.1 - 0.49 10.4 4.2 1.8 8.6 0.3 2.4 2 0 0 2 2 2 0 Laminin Domain II DUF3552 PF12072.8 EPE32298.1 - 0.79 9.1 3.1 18 4.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) EzrA PF06160.12 EPE32298.1 - 0.79 7.8 3.9 0.81 7.8 0.6 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 EPE32298.1 - 1 9.4 3.7 0.97 9.4 0.9 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uds1 PF15456.6 EPE32300.1 - 2.5e-41 140.9 4.5 2.5e-41 140.9 4.5 7.1 5 1 1 6 6 6 2 Up-regulated During Septation HIP1_clath_bdg PF16515.5 EPE32300.1 - 0.0014 19.2 8.1 0.0014 19.2 8.1 8.3 5 3 3 9 9 9 2 Clathrin-binding domain of Huntingtin-interacting protein 1 Seryl_tRNA_N PF02403.22 EPE32300.1 - 0.022 15.0 1.9 0.022 15.0 1.9 8.9 6 2 3 9 9 9 0 Seryl-tRNA synthetase N-terminal domain Erf4 PF10256.9 EPE32300.1 - 0.078 13.1 1.2 15 5.7 0.0 3.4 2 1 1 3 3 3 0 Golgin subfamily A member 7/ERF4 family DUF4634 PF15465.6 EPE32300.1 - 7.3 6.9 7.2 0.69 10.2 1.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4634) Peptidase_M41 PF01434.18 EPE32301.1 - 3.1e-60 203.3 0.2 5.5e-60 202.5 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EPE32301.1 - 1.2e-41 142.2 0.0 3.6e-41 140.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPE32301.1 - 8.3e-11 41.5 0.0 2e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 EPE32301.1 - 3.6e-05 23.1 0.0 7.3e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EPE32301.1 - 4.1e-05 23.6 0.0 0.00018 21.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPE32301.1 - 8.7e-05 23.0 1.3 0.00069 20.0 0.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EPE32301.1 - 0.0003 21.1 0.1 0.073 13.3 0.1 3.3 2 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EPE32301.1 - 0.00038 20.6 0.7 0.011 15.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EPE32301.1 - 0.00073 19.3 0.0 0.0024 17.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EPE32301.1 - 0.012 15.4 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EPE32301.1 - 0.016 14.8 1.3 0.69 9.5 0.4 2.4 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EPE32301.1 - 0.021 14.2 0.2 0.049 13.0 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EPE32301.1 - 0.023 14.9 0.3 0.28 11.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 EPE32301.1 - 0.032 14.3 0.0 0.097 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 EPE32301.1 - 0.034 13.7 0.1 0.26 10.8 0.1 2.2 1 1 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 EPE32301.1 - 0.062 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 EPE32301.1 - 0.096 13.2 0.0 0.27 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EPE32301.1 - 0.098 11.9 1.6 0.55 9.5 0.4 2.3 1 1 1 2 2 2 0 Zeta toxin zf-C2H2 PF00096.26 EPE32302.1 - 3.5e-20 71.3 31.2 9.3e-06 25.8 1.8 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPE32302.1 - 2.7e-18 65.5 27.6 2.1e-06 27.9 0.6 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPE32302.1 - 6e-09 36.0 28.2 0.016 16.0 1.3 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE32302.1 - 0.00025 21.2 2.2 0.76 10.1 0.2 3.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EPE32302.1 - 0.015 15.1 2.0 0.015 15.1 2.0 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 EPE32302.1 - 0.025 14.9 10.8 1.5 9.1 7.2 2.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-TRAF PF02176.18 EPE32302.1 - 0.032 14.9 2.4 0.032 14.9 2.4 3.5 1 1 2 3 3 3 0 TRAF-type zinc finger zf-met PF12874.7 EPE32302.1 - 0.29 11.6 11.4 0.23 11.9 0.6 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 EPE32302.1 - 2.8 8.6 16.6 10 6.8 0.3 4.9 3 1 2 5 5 5 0 FOXP coiled-coil domain Aldedh PF00171.22 EPE32303.1 - 6e-26 91.0 0.0 8.5e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NTP_transf_2 PF01909.23 EPE32303.1 - 5.8e-07 29.7 0.0 1.5e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EPE32303.1 - 2.4e-06 27.5 0.0 9e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase PTA_PTB PF01515.19 EPE32303.1 - 0.0037 16.6 0.0 0.009 15.4 0.0 1.5 2 0 0 2 2 2 1 Phosphate acetyl/butaryl transferase SMODS PF18144.1 EPE32303.1 - 0.012 15.8 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain GMC_oxred_N PF00732.19 EPE32304.1 - 2e-57 194.8 0.0 2.6e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE32304.1 - 2.2e-36 125.6 0.0 3.4e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EPE32304.1 - 4.8e-05 22.6 0.0 7.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPE32304.1 - 7.6e-05 22.9 0.0 0.00017 21.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE32304.1 - 0.00058 19.5 0.0 0.0016 18.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPE32304.1 - 0.0014 17.8 0.0 0.0052 15.9 0.0 1.9 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE32304.1 - 0.0044 16.3 0.0 0.0074 15.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE32304.1 - 0.02 14.2 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EPE32304.1 - 0.079 13.5 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE32304.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Scytalone_dh PF02982.14 EPE32305.1 - 2.2e-76 255.1 0.7 2.8e-76 254.7 0.7 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 EPE32305.1 - 3e-08 33.8 0.4 4e-08 33.4 0.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain Fungal_trans_2 PF11951.8 EPE32306.1 - 2.5e-10 39.7 1.3 9.9e-10 37.8 0.0 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE32306.1 - 7.8e-06 25.9 9.9 1.5e-05 25.0 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L38e PF01781.18 EPE32308.1 - 7.8e-33 112.4 1.7 9.2e-33 112.2 1.7 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Ish1 PF10281.9 EPE32309.1 - 7.1e-07 29.4 0.4 1e-06 28.9 0.4 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein SAP PF02037.27 EPE32309.1 - 0.0026 17.5 0.2 0.0054 16.5 0.2 1.6 1 1 0 1 1 1 1 SAP domain HeH PF12949.7 EPE32309.1 - 0.0047 16.6 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 HeH/LEM domain Mtr2 PF10429.9 EPE32311.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.6 1 1 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Mesd PF10185.9 EPE32311.1 - 0.019 14.9 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor NTF2 PF02136.20 EPE32311.1 - 0.033 14.8 0.0 0.077 13.6 0.0 1.7 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain tRNA-synt_1g PF09334.11 EPE32312.1 - 2.2e-101 339.4 0.2 4e-100 335.3 0.2 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EPE32312.1 - 1.7e-25 89.4 4.4 9.7e-11 40.6 0.0 4.0 1 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EPE32312.1 - 2.2e-08 33.8 0.0 5e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Peptidase_M48_N PF16491.5 EPE32314.1 - 1.9e-67 226.7 7.7 1.9e-67 226.7 7.7 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EPE32314.1 - 9e-43 146.3 0.0 1.9e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EPE32314.1 - 0.067 12.4 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 BlaR1 peptidase M56 Ku_N PF03731.15 EPE32316.1 - 0.22 11.2 0.7 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 Ku70/Ku80 N-terminal alpha/beta domain NMO PF03060.15 EPE32317.1 - 2e-51 175.4 0.5 2.5e-51 175.0 0.5 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EPE32317.1 - 1.9e-06 27.1 5.5 6.7e-06 25.3 2.7 2.4 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EPE32317.1 - 0.0032 16.5 3.9 0.0051 15.9 3.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase GATase_7 PF13537.6 EPE32317.1 - 0.2 11.5 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain Taxilin PF09728.9 EPE32319.1 - 7.7e-92 307.8 55.8 7.7e-92 307.8 55.8 1.5 2 0 0 2 2 2 1 Myosin-like coiled-coil protein ERM PF00769.19 EPE32319.1 - 0.016 15.0 14.7 0.016 15.0 14.7 3.9 1 1 0 2 2 2 0 Ezrin/radixin/moesin family Chromo_2 PF18704.1 EPE32319.1 - 0.063 13.6 0.1 0.4 11.0 0.1 2.5 1 0 0 1 1 1 0 Chromatin organization modifier domain 2 M16C_assoc PF08367.11 EPE32320.1 - 1.7e-82 276.4 0.0 2.4e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EPE32320.1 - 2.5e-32 112.4 0.0 8.1e-20 71.6 0.0 3.3 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EPE32320.1 - 1.3e-06 28.5 0.0 5.1e-05 23.3 0.0 2.9 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) DUF768 PF05589.11 EPE32320.1 - 0.11 12.5 0.1 28 4.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF768) Acetyltransf_3 PF13302.7 EPE32321.1 - 2.8e-15 57.2 0.1 4.3e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE32321.1 - 0.00032 20.9 0.1 0.00061 20.0 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family HET PF06985.11 EPE32322.1 - 2.5e-24 86.3 0.0 9.8e-24 84.4 0.0 2.1 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) TgMIC1 PF11476.8 EPE32323.1 - 0.22 11.3 0.0 0.44 10.3 0.0 1.4 1 0 0 1 1 1 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Radial_spoke_3 PF06098.11 EPE32324.1 - 0.13 11.5 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Radial spoke protein 3 zf-C2H2_2 PF12756.7 EPE32325.1 - 6e-27 93.9 14.6 1.8e-24 86.0 1.5 3.3 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EPE32325.1 - 0.00026 21.2 3.1 0.00026 21.2 3.1 3.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Cdh1_DBD_1 PF18196.1 EPE32329.1 - 0.054 13.8 0.5 0.054 13.8 0.5 3.0 2 1 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 DNA_pol_E_B PF04042.16 EPE32330.1 - 2.7e-47 160.8 0.0 3.6e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EPE32330.1 - 1.3e-41 141.8 0.0 2e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Sporozoite_P67 PF05642.11 EPE32331.1 - 1.1 7.2 11.1 1.3 7.1 11.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Aa_trans PF01490.18 EPE32332.1 - 1.2e-87 294.3 33.9 1.4e-87 294.1 33.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF202 PF02656.15 EPE32332.1 - 0.13 12.7 3.1 0.17 12.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Cytochrome-c551 PF10643.9 EPE32332.1 - 0.65 9.5 4.0 1.6 8.3 4.0 1.6 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 AA_permease PF00324.21 EPE32333.1 - 2.8e-55 187.8 33.8 3.6e-55 187.4 33.8 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EPE32333.1 - 1.5e-23 83.5 3.4 1.4e-09 37.5 0.0 3.8 4 0 0 4 4 4 3 Solute carrier family 12 AA_permease_2 PF13520.6 EPE32333.1 - 4.7e-17 61.9 39.5 7.4e-17 61.3 39.5 1.2 1 0 0 1 1 1 1 Amino acid permease WBP-1 PF11669.8 EPE32333.1 - 0.022 15.4 0.6 1.4 9.6 0.9 2.8 2 0 0 2 2 2 0 WW domain-binding protein 1 NMO PF03060.15 EPE32334.1 - 7.6e-32 111.0 2.9 7.1e-25 88.1 1.8 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EPE32334.1 - 5.8e-08 32.1 1.7 8.2e-08 31.6 1.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EPE32334.1 - 1.2e-05 24.6 0.0 0.1 11.6 0.3 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EPE32334.1 - 0.00048 19.4 0.3 0.00085 18.6 0.3 1.3 1 1 0 1 1 1 1 Conserved region in glutamate synthase RNA_pol_L_2 PF13656.6 EPE32335.1 - 5.7e-25 86.9 0.0 7.3e-25 86.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EPE32335.1 - 1e-09 37.7 0.0 1.5e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain adh_short PF00106.25 EPE32336.1 - 6.5e-35 120.4 0.4 1.1e-34 119.6 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE32336.1 - 2.8e-25 89.2 0.2 7.2e-25 87.9 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EPE32336.1 - 4.5e-07 29.5 0.0 1.1e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EPE32336.1 - 3.9e-06 26.9 0.2 6.3e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EPE32336.1 - 5e-05 23.3 0.1 0.00011 22.1 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EPE32336.1 - 0.00066 19.2 0.0 0.0016 18.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPE32336.1 - 0.00085 18.9 0.0 0.0021 17.7 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_2 PF03446.15 EPE32336.1 - 0.0073 16.5 0.1 0.021 15.0 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.15 EPE32336.1 - 0.017 15.0 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NKWYS PF10364.9 EPE32336.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein RmlD_sub_bind PF04321.17 EPE32336.1 - 0.082 12.0 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain ApbA PF02558.16 EPE32336.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Orn_Arg_deC_N PF02784.16 EPE32337.1 - 4.8e-83 278.3 0.0 6.2e-83 278.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EPE32337.1 - 4.2e-18 65.4 0.0 6.5e-18 64.8 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 EPE32337.1 - 0.16 11.4 0.0 0.43 10.0 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel DNA_pol_A_exo1 PF01612.20 EPE32338.1 - 7e-15 55.2 0.0 1.1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.22 EPE32339.1 - 1.4e-22 79.1 0.2 1.6e-22 79.0 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EPE32339.1 - 0.0095 16.1 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2069 PF09842.9 EPE32341.1 - 0.074 13.3 1.4 0.15 12.3 1.4 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2069) DOPA_dioxygen PF08883.11 EPE32342.1 - 9.7e-44 147.9 0.1 1.2e-43 147.7 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Zn_clus PF00172.18 EPE32343.1 - 3.5e-07 30.2 7.8 6.4e-07 29.4 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CK_II_beta PF01214.18 EPE32344.1 - 1e-74 250.3 0.0 1.6e-74 249.7 0.0 1.3 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.8 EPE32344.1 - 0.038 15.0 7.2 0.038 15.0 7.2 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.11 EPE32344.1 - 0.087 11.3 2.5 0.12 10.9 2.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SGT1 PF07093.11 EPE32344.1 - 0.25 9.7 2.2 0.33 9.3 2.2 1.1 1 0 0 1 1 1 0 SGT1 protein CDC45 PF02724.14 EPE32344.1 - 1.1 7.4 6.5 1.6 7.0 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein MRC1 PF09444.10 EPE32344.1 - 1.3 9.5 14.6 15 6.0 0.1 2.2 2 0 0 2 2 2 0 MRC1-like domain DUF4637 PF15470.6 EPE32344.1 - 1.4 8.6 5.8 3.3 7.4 5.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) NOA36 PF06524.12 EPE32344.1 - 1.5 8.1 6.3 2.6 7.3 6.3 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EPE32344.1 - 6.6 4.7 7.7 8.8 4.3 7.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 EPE32344.1 - 9.4 6.3 13.6 0.41 10.7 7.7 1.6 2 0 0 2 2 2 0 YL1 nuclear protein Glyco_hydro_3_C PF01915.22 EPE32345.1 - 1.5e-54 185.1 0.0 2.8e-54 184.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE32345.1 - 1e-39 136.8 0.0 1.9e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE32345.1 - 3e-23 81.7 0.1 6.7e-23 80.6 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Methyltransf_23 PF13489.6 EPE32348.1 - 6.1e-25 88.0 0.0 9.3e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE32348.1 - 2.7e-05 24.8 0.0 6.9e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE32348.1 - 0.0013 19.3 0.0 0.011 16.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE32348.1 - 0.0034 18.1 0.0 0.0073 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_C48 PF02902.19 EPE32349.1 - 4.3e-07 30.0 0.3 7.1e-07 29.3 0.3 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RBM39linker PF15519.6 EPE32349.1 - 0.18 12.9 0.3 1 10.5 0.0 2.4 3 0 0 3 3 3 0 linker between RRM2 and RRM3 domains in RBM39 protein Ribosomal_S11 PF00411.19 EPE32350.1 - 0.16 12.3 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S11 Zn_clus PF00172.18 EPE32351.1 - 0.014 15.5 1.7 0.04 14.1 1.7 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_47 PF01532.20 EPE32352.1 - 1.2e-137 459.5 0.0 1.4e-137 459.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ETF_QO PF05187.13 EPE32353.1 - 1.4e-48 163.3 0.5 2.3e-48 162.7 0.5 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 EPE32353.1 - 1.3e-08 34.9 0.0 5e-08 33.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE32353.1 - 1.8e-08 34.3 1.2 0.00012 21.9 0.7 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EPE32353.1 - 1.1e-06 28.0 0.0 0.0021 17.3 0.2 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 EPE32353.1 - 1.4e-05 24.4 1.5 0.0043 16.2 1.3 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EPE32353.1 - 6.1e-05 22.4 0.0 0.00014 21.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE32353.1 - 0.00029 19.7 0.5 0.00043 19.1 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 EPE32353.1 - 0.00061 19.1 0.1 0.0011 18.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EPE32353.1 - 0.0007 18.6 0.2 0.21 10.4 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 EPE32353.1 - 0.0011 19.0 0.3 0.0034 17.4 0.3 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EPE32353.1 - 0.0025 17.2 0.5 0.0041 16.4 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EPE32353.1 - 0.0042 16.5 0.1 0.0058 16.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EPE32353.1 - 0.0064 17.0 0.2 5.9 7.5 0.3 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.7 EPE32353.1 - 0.029 15.0 0.8 0.077 13.6 0.8 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Amino_oxidase PF01593.24 EPE32353.1 - 0.039 13.3 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EPE32353.1 - 0.091 11.8 0.2 0.13 11.2 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_2 PF12797.7 EPE32353.1 - 0.17 12.1 0.7 0.43 10.8 0.7 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain GIDA PF01134.22 EPE32353.1 - 0.2 10.7 0.4 0.3 10.1 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A SR-25 PF10500.9 EPE32354.1 - 3.6 7.1 26.1 3.9 7.0 6.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Glyco_trans_1_4 PF13692.6 EPE32355.1 - 4.4e-09 36.9 0.0 1.1e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EPE32355.1 - 6e-09 35.7 0.0 1.6e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF3492 PF11997.8 EPE32355.1 - 9.6e-05 22.2 0.0 0.00095 19.0 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) SH3_17 PF18350.1 EPE32356.1 - 0.022 14.6 0.1 0.059 13.3 0.1 1.7 1 0 0 1 1 1 0 Restriction endonuclease SH3 domain Polysacc_deac_1 PF01522.21 EPE32356.1 - 0.041 13.8 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Polysaccharide deacetylase DHBP_synthase PF00926.19 EPE32356.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 3,4-dihydroxy-2-butanone 4-phosphate synthase GDP_Man_Dehyd PF16363.5 EPE32357.1 - 5.6e-37 127.9 0.0 4.4e-35 121.6 0.0 2.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EPE32357.1 - 1.5e-34 119.5 0.0 2.9e-32 112.1 0.0 2.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EPE32357.1 - 2.8e-07 30.0 0.0 0.00077 18.7 0.0 3.8 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EPE32357.1 - 5.8e-07 28.9 0.0 9.3e-06 25.0 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EPE32357.1 - 5.7e-06 25.5 0.0 0.0046 16.0 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EPE32357.1 - 0.00078 19.0 0.0 0.0016 17.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Pyr_redox_2 PF07992.14 EPE32357.1 - 0.0024 17.1 0.0 0.0037 16.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE32357.1 - 0.0058 16.8 0.0 0.021 15.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE32357.1 - 0.0096 15.5 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase KR PF08659.10 EPE32357.1 - 0.012 15.5 0.0 0.036 14.0 0.0 1.7 1 1 0 1 1 1 0 KR domain 3HCDH_N PF02737.18 EPE32357.1 - 0.059 13.2 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 EPE32357.1 - 0.063 12.8 0.4 0.21 11.1 0.1 2.0 3 0 0 3 3 3 0 NmrA-like family TPMT PF05724.11 EPE32357.1 - 0.067 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) ThiF PF00899.21 EPE32357.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 ThiF family UDPG_MGDP_dh_N PF03721.14 EPE32357.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 EPE32357.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF2014 PF09427.10 EPE32359.1 - 1.3e-114 382.0 0.1 1.9e-114 381.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 EPE32359.1 - 1.3e-16 60.3 0.5 2.5e-16 59.4 0.5 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2076 PF09849.9 EPE32359.1 - 0.77 9.8 11.7 0.021 14.9 2.6 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Pyr_redox_2 PF07992.14 EPE32360.1 - 3.2e-45 154.6 0.6 4.8e-45 154.0 0.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 EPE32360.1 - 5.3e-19 68.3 0.0 9.7e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 EPE32360.1 - 3.2e-17 62.8 6.3 5.5e-16 58.9 1.4 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 EPE32360.1 - 4e-15 55.6 0.0 1.1e-14 54.2 0.0 1.8 2 0 0 2 2 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 EPE32360.1 - 2e-14 53.7 6.4 4e-10 39.9 6.2 2.6 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 EPE32360.1 - 2.9e-13 49.5 0.2 2.9e-12 46.4 0.0 2.4 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 EPE32360.1 - 2e-09 37.1 0.0 6.3e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 EPE32360.1 - 9.7e-06 25.4 0.0 0.11 12.5 0.0 3.7 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain Amino_oxidase PF01593.24 EPE32360.1 - 0.00018 21.0 0.2 0.048 12.9 0.0 2.2 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EPE32360.1 - 0.00061 19.8 0.1 2.1 8.4 0.0 3.7 3 1 0 4 4 4 1 FAD-NAD(P)-binding TrkA_N PF02254.18 EPE32360.1 - 0.046 14.0 0.7 3.8 7.8 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain K_oxygenase PF13434.6 EPE32360.1 - 0.11 11.6 0.0 0.5 9.5 0.0 1.9 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pex19 PF04614.12 EPE32360.1 - 0.21 11.4 0.6 0.92 9.2 0.0 1.9 2 0 0 2 2 2 0 Pex19 protein family Bac_rhodopsin PF01036.18 EPE32361.1 - 8.3e-34 117.1 17.6 1.1e-33 116.7 17.6 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Frag1 PF10277.9 EPE32361.1 - 0.09 12.3 13.8 0.33 10.4 13.8 1.9 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family YwcE PF17368.2 EPE32361.1 - 0.16 12.6 6.1 2.3 8.9 0.4 2.6 2 0 0 2 2 2 0 Spore morphogenesis and germination YwcE Prefoldin PF02996.17 EPE32363.1 - 1.6e-26 92.6 0.1 2.1e-26 92.2 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EPE32363.1 - 0.0016 18.3 2.2 0.24 11.4 0.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit Med30 PF11315.8 EPE32363.1 - 0.0058 16.8 0.1 0.85 9.8 0.0 2.1 2 0 0 2 2 2 1 Mediator complex subunit 30 DUF4140 PF13600.6 EPE32363.1 - 0.017 15.6 0.1 1.2 9.7 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DASH_Dad2 PF08654.10 EPE32363.1 - 0.031 14.7 1.3 5.7 7.4 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad2 Fib_alpha PF08702.10 EPE32363.1 - 0.036 14.2 0.2 8 6.6 0.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 EPE32363.1 - 0.046 13.9 0.5 0.32 11.2 0.1 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding GIT_CC PF16559.5 EPE32363.1 - 0.049 13.5 0.7 0.1 12.5 0.7 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cep57_MT_bd PF06657.13 EPE32363.1 - 0.13 12.8 1.3 0.41 11.1 0.1 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 AAA PF00004.29 EPE32364.1 - 7.4e-16 58.8 0.0 1.7e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPE32364.1 - 1.3e-10 41.7 0.0 9.5e-10 38.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EPE32364.1 - 3.1e-10 40.7 0.0 3.7e-09 37.2 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_lid_10 PF17872.1 EPE32364.1 - 1e-09 38.4 0.3 1e-09 38.4 0.3 2.3 3 0 0 3 3 3 1 AAA lid domain AAA_19 PF13245.6 EPE32364.1 - 0.00094 19.5 0.0 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 EPE32364.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_28 PF13521.6 EPE32364.1 - 0.0027 18.0 0.0 0.028 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EPE32364.1 - 0.011 16.2 0.0 0.067 13.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EPE32364.1 - 0.018 14.3 0.0 0.05 12.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 EPE32364.1 - 0.021 14.6 0.0 0.021 14.6 0.0 2.4 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 EPE32364.1 - 0.025 14.5 0.0 0.07 13.0 0.0 1.8 1 1 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 EPE32364.1 - 0.032 14.2 0.9 0.49 10.3 0.0 2.9 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea ssDBP PF17878.1 EPE32364.1 - 0.048 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Single-stranded DNA-binding protein AAA_32 PF13654.6 EPE32364.1 - 0.049 12.4 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EPE32364.1 - 0.053 13.4 0.1 1.1 9.1 0.0 3.0 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 EPE32364.1 - 0.078 12.1 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.22 EPE32364.1 - 0.082 13.3 0.1 0.61 10.5 0.0 2.6 3 0 0 3 3 2 0 RNA helicase NTPase_1 PF03266.15 EPE32364.1 - 0.12 12.3 0.5 0.76 9.7 0.1 2.3 2 0 0 2 2 2 0 NTPase WD40 PF00400.32 EPE32365.1 - 5.8e-44 147.2 13.3 6.2e-09 36.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE32365.1 - 5.6e-06 26.6 0.6 3.9 7.9 0.0 5.0 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPE32365.1 - 0.044 12.4 2.8 12 4.4 0.0 4.0 1 1 2 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 EPE32365.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain W_rich_C PF07483.11 EPE32365.1 - 0.15 12.3 0.4 1.1 9.5 0.1 2.6 3 0 0 3 3 3 0 Tryptophan-rich Synechocystis species C-terminal domain Ank_5 PF13857.6 EPE32366.1 - 2.4e-28 97.8 0.7 2.9e-07 30.6 0.0 4.9 1 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE32366.1 - 2.8e-27 95.1 0.2 9e-13 48.6 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE32366.1 - 7.5e-25 87.0 1.6 7.9e-06 26.3 0.0 5.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE32366.1 - 7.4e-21 72.0 0.7 0.00048 20.4 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 EPE32366.1 - 5e-18 64.7 5.6 1.1e-05 25.7 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat TMF_TATA_bd PF12325.8 EPE32367.1 - 2.1e-39 134.3 10.0 2.1e-39 134.3 10.0 7.4 3 1 5 9 9 9 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EPE32367.1 - 6.1e-19 67.8 16.3 6.1e-19 67.8 16.3 7.7 5 4 2 7 7 7 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 EPE32367.1 - 0.00014 22.1 3.8 0.00014 22.1 3.8 5.6 3 1 2 5 5 5 1 Autophagy protein 16 (ATG16) Flagellin_C PF00700.21 EPE32367.1 - 0.31 11.4 0.1 0.31 11.4 0.1 5.1 5 0 0 5 5 5 0 Bacterial flagellin C-terminal helical region Ceramidase PF05875.12 EPE32368.1 - 4.1e-107 357.5 10.3 5e-107 357.2 10.3 1.0 1 0 0 1 1 1 1 Ceramidase DUF2157 PF09925.9 EPE32368.1 - 0.01 15.6 2.6 0.031 14.1 1.4 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF2070 PF09843.9 EPE32368.1 - 4 5.6 7.2 5.3 5.2 7.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Prefoldin_2 PF01920.20 EPE32369.1 - 1.2e-20 73.4 3.6 1.5e-20 73.1 3.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit YabA PF06156.13 EPE32369.1 - 0.0019 18.8 2.3 1.1 10.0 0.1 2.0 2 0 0 2 2 2 2 Initiation control protein YabA Rootletin PF15035.6 EPE32369.1 - 0.0024 17.9 2.2 0.14 12.2 0.0 2.0 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion DUF2570 PF10828.8 EPE32369.1 - 0.003 17.4 2.6 0.11 12.3 1.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2570) CC2-LZ PF16516.5 EPE32369.1 - 0.012 15.9 4.8 1.6 9.1 0.2 2.1 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF1664 PF07889.12 EPE32369.1 - 0.025 14.6 3.4 0.4 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) AIP3 PF03915.13 EPE32369.1 - 0.026 13.6 2.3 0.029 13.5 2.3 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 DUF1640 PF07798.11 EPE32369.1 - 0.033 14.3 4.3 0.049 13.7 4.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) FlxA PF14282.6 EPE32369.1 - 0.035 14.1 9.7 0.36 10.8 5.6 2.1 2 0 0 2 2 2 0 FlxA-like protein BLOC1_2 PF10046.9 EPE32369.1 - 0.043 14.1 5.4 0.16 12.3 0.2 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 EPE32369.1 - 0.051 13.6 6.9 0.14 12.1 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2681 PF10883.8 EPE32369.1 - 0.07 13.6 8.2 2.8 8.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) T6PP_N PF18572.1 EPE32369.1 - 0.086 12.7 1.4 0.18 11.6 1.4 1.6 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain USP8_interact PF08941.10 EPE32369.1 - 0.12 12.2 3.9 0.081 12.7 0.6 1.9 2 0 0 2 2 2 0 USP8 interacting Tropomyosin_1 PF12718.7 EPE32369.1 - 0.12 12.6 5.2 1 9.5 0.3 2.1 2 0 0 2 2 2 0 Tropomyosin like Jnk-SapK_ap_N PF09744.9 EPE32369.1 - 0.12 12.6 6.8 0.36 11.0 0.1 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 CtIP_N PF10482.9 EPE32369.1 - 0.13 12.3 6.2 0.43 10.6 2.9 2.1 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Fib_alpha PF08702.10 EPE32369.1 - 0.17 12.1 8.1 0.67 10.1 0.1 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 EPE32369.1 - 0.18 11.9 9.5 1.4 9.0 3.8 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 EPE32369.1 - 0.18 12.2 0.6 0.18 12.2 0.6 2.2 2 0 0 2 2 2 0 Cell division protein ZapB OmpH PF03938.14 EPE32369.1 - 0.2 12.0 7.8 1.2 9.4 0.1 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) RasGAP_C PF03836.15 EPE32369.1 - 0.24 11.5 5.9 0.53 10.4 0.2 2.1 2 0 0 2 2 2 0 RasGAP C-terminus Spc24 PF08286.11 EPE32369.1 - 0.28 11.5 3.9 4.8 7.5 0.1 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 PspA_IM30 PF04012.12 EPE32369.1 - 0.28 10.8 10.7 2 8.0 0.1 2.0 2 0 0 2 2 2 0 PspA/IM30 family Tektin PF03148.14 EPE32369.1 - 0.34 9.6 7.7 0.56 8.9 0.2 2.0 2 0 0 2 2 2 0 Tektin family TolA_bind_tri PF16331.5 EPE32369.1 - 0.35 11.0 13.8 0.45 10.6 0.2 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation Lectin_N PF03954.14 EPE32369.1 - 0.4 10.4 5.4 5.6 6.7 0.1 2.1 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Prefoldin PF02996.17 EPE32369.1 - 0.53 10.2 9.1 3 7.8 0.1 2.1 2 0 0 2 2 2 0 Prefoldin subunit SlyX PF04102.12 EPE32369.1 - 0.66 10.6 7.4 4 8.1 3.7 2.2 2 0 0 2 2 2 0 SlyX Cnn_1N PF07989.11 EPE32369.1 - 0.79 9.9 6.3 1.7 8.9 0.1 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF724 PF05266.14 EPE32369.1 - 1.1 9.1 6.4 2.1 8.2 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) THOC7 PF05615.13 EPE32369.1 - 1.2 9.4 8.4 5.5 7.3 8.4 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 DUF16 PF01519.16 EPE32369.1 - 1.2 9.6 7.3 5.2 7.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF3450 PF11932.8 EPE32369.1 - 1.5 8.1 10.3 4.3 6.6 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Swi5 PF07061.11 EPE32369.1 - 3.5 7.8 8.4 3.3 7.9 0.6 2.1 2 0 0 2 2 2 0 Swi5 Csm1_N PF18504.1 EPE32369.1 - 6 7.3 10.3 3 8.3 0.3 2.5 2 1 0 2 2 2 0 Csm1 N-terminal domain Mito_carr PF00153.27 EPE32371.1 - 7.4e-47 157.2 4.3 5.3e-18 64.7 0.3 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein CN_hydrolase PF00795.22 EPE32372.1 - 9.3e-50 169.4 0.0 1e-49 169.2 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PEMT PF04191.13 EPE32373.1 - 1.5e-31 108.9 2.8 2.5e-31 108.2 2.8 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase RXT2_N PF08595.11 EPE32374.1 - 1.4e-47 161.6 2.8 2.7e-47 160.7 0.1 2.6 2 0 0 2 2 2 1 RXT2-like, N-terminal Homoserine_dh PF00742.19 EPE32375.1 - 4.4e-49 166.7 0.0 6.3e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EPE32375.1 - 5.8e-19 68.9 0.0 9.6e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain IGPS PF00218.21 EPE32375.1 - 0.029 13.5 0.1 0.046 12.9 0.1 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Methyltransf_4 PF02390.17 EPE32377.1 - 3.9e-56 189.2 0.0 5.9e-56 188.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EPE32377.1 - 0.0009 19.9 0.0 0.002 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE32377.1 - 0.0027 18.4 0.0 0.0082 16.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EPE32377.1 - 0.0081 15.7 0.0 0.016 14.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EPE32377.1 - 0.017 15.1 0.0 0.041 13.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain DUF4191 PF13829.6 EPE32377.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) CMAS PF02353.20 EPE32377.1 - 0.028 13.7 0.0 0.066 12.5 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EPE32377.1 - 0.062 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EPE32377.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Psb28 PF03912.14 EPE32377.1 - 0.12 12.7 0.2 3.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Psb28 protein PXA PF02194.15 EPE32378.1 - 4.2e-45 153.9 0.7 4.2e-45 153.9 0.7 2.2 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 EPE32378.1 - 1e-27 96.9 0.0 3.3e-27 95.3 0.0 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 EPE32378.1 - 4.9e-21 74.8 0.6 1.5e-20 73.3 0.6 1.8 1 0 0 1 1 1 1 PX domain RGS PF00615.19 EPE32378.1 - 2.9e-09 37.2 0.5 9e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 Regulator of G protein signaling domain GIT_CC PF16559.5 EPE32378.1 - 0.17 11.8 1.8 0.5 10.3 1.8 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor ESCRT-II PF05871.12 EPE32379.1 - 3.4e-53 179.7 1.3 3.9e-53 179.4 1.3 1.0 1 0 0 1 1 1 1 ESCRT-II complex subunit BRCT PF00533.26 EPE32380.1 - 7.8e-34 115.9 0.1 2.9e-09 37.2 0.0 6.4 6 0 0 6 6 6 6 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EPE32380.1 - 6.6e-33 112.6 0.0 1.5e-29 101.8 0.0 4.2 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 EPE32380.1 - 5e-31 106.4 3.4 2.2e-20 72.3 0.2 5.5 6 1 0 6 6 6 3 twin BRCT domain BRCT_2 PF16589.5 EPE32380.1 - 3.7e-28 97.7 0.0 2.4e-06 27.8 0.0 6.3 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EPE32380.1 - 5.4e-09 36.2 0.0 0.67 10.3 0.0 4.5 4 0 0 4 4 4 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EPE32380.1 - 0.00036 20.6 0.0 3.5 7.7 0.0 4.0 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain Abhydrolase_6 PF12697.7 EPE32381.1 - 3.3e-11 44.2 0.1 4.6e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE32381.1 - 2.4e-05 24.1 0.0 3.6e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE32381.1 - 2.4e-05 23.7 0.0 4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EPE32381.1 - 0.11 11.2 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Ndr family Gryzun PF07919.12 EPE32382.1 - 1.3e-223 744.1 0.0 1.7e-223 743.7 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 EPE32382.1 - 1.4e-87 293.6 0.4 3.1e-78 262.9 1.5 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 EPE32382.1 - 0.038 14.0 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking DUF4078 PF13300.6 EPE32383.1 - 2.1e-28 98.5 18.3 2.1e-28 98.5 18.3 2.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4078) AF-4 PF05110.13 EPE32385.1 - 2.7 5.9 6.5 3.9 5.4 6.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Asp PF00026.23 EPE32386.1 - 4.1e-12 46.2 0.0 6.2e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease FixQ PF05545.11 EPE32386.1 - 0.002 18.1 0.0 0.0061 16.5 0.0 1.8 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ ADH_N PF08240.12 EPE32390.1 - 2.8e-26 91.5 0.6 6.3e-26 90.4 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE32390.1 - 1.2e-14 54.4 1.7 2.2e-14 53.6 1.7 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE32390.1 - 2.7e-05 25.2 1.8 0.0019 19.2 1.8 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EPE32390.1 - 0.0035 17.2 0.0 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase Protoglobin PF11563.8 EPE32391.1 - 0.041 13.8 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Protoglobin NOA36 PF06524.12 EPE32391.1 - 3 7.1 8.7 5.1 6.3 8.7 1.3 1 0 0 1 1 1 0 NOA36 protein Med13_C PF06333.12 EPE32391.1 - 3.7 6.7 5.4 6.2 6.0 5.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain FAM176 PF14851.6 EPE32391.1 - 3.8 7.1 6.1 0.85 9.3 2.5 1.7 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 EPE32391.1 - 7.8 4.5 11.6 21 3.0 9.6 2.1 2 0 0 2 2 2 0 DNA polymerase phi CENP-B_dimeris PF09026.10 EPE32391.1 - 8.2 6.9 12.2 21 5.6 12.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain APH PF01636.23 EPE32392.1 - 2.1e-10 40.9 0.0 5.8e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE32392.1 - 0.078 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ADH_N PF08240.12 EPE32393.1 - 2.8e-21 75.4 4.4 6.1e-21 74.4 4.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE32393.1 - 4.7e-21 75.1 0.9 1e-20 74.0 0.9 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE32393.1 - 7.8e-08 33.4 0.4 1.4e-07 32.6 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPE32393.1 - 0.045 13.0 3.0 0.074 12.3 3.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain His_Phos_2 PF00328.22 EPE32394.1 - 4.8e-45 154.5 0.0 5.8e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Dicer_N PF17895.1 EPE32394.1 - 0.17 11.8 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Giardia Dicer N-terminal domain Sel1 PF08238.12 EPE32395.1 - 6e-34 115.7 25.7 7e-06 26.6 0.8 7.7 7 0 0 7 7 7 7 Sel1 repeat Chitin_synth_2 PF03142.15 EPE32396.1 - 5.4e-288 955.9 0.1 8.2e-288 955.3 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EPE32396.1 - 3.1e-14 53.3 3.7 9.2e-14 51.8 3.7 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EPE32396.1 - 7e-11 42.4 0.0 4.3e-09 36.6 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EPE32396.1 - 0.00067 19.2 0.0 0.019 14.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 DUF639 PF04842.12 EPE32396.1 - 0.032 13.7 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Cyt-b5 PF00173.28 EPE32396.1 - 0.034 14.3 0.1 2.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 EPE32396.1 - 0.073 12.9 0.0 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Pkinase PF00069.25 EPE32397.1 - 2e-70 237.2 0.0 2.9e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE32397.1 - 1.7e-39 135.7 0.0 2.8e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EPE32397.1 - 1.5e-09 37.9 0.6 0.00065 19.8 0.0 3.1 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 EPE32397.1 - 4.1e-09 36.2 0.0 4.1e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EPE32397.1 - 0.0019 17.2 0.1 0.0033 16.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EPE32397.1 - 0.0019 17.6 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EPE32397.1 - 0.0026 16.6 0.2 0.027 13.3 0.2 2.2 2 0 0 2 2 2 1 Fungal protein kinase SPX PF03105.19 EPE32397.1 - 0.14 12.1 8.9 0.22 11.4 8.7 1.5 1 1 0 1 1 1 0 SPX domain OPA3 PF07047.12 EPE32398.1 - 4.7e-44 149.1 6.7 1.6e-43 147.5 6.7 1.7 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) HOOK PF05622.12 EPE32398.1 - 0.00095 17.4 5.3 0.00095 17.4 5.3 1.4 2 0 0 2 2 2 1 HOOK protein HemX PF04375.14 EPE32398.1 - 0.0092 15.3 1.8 0.019 14.3 0.1 1.9 2 0 0 2 2 2 1 HemX, putative uroporphyrinogen-III C-methyltransferase UPF0242 PF06785.11 EPE32398.1 - 0.011 15.9 0.2 0.011 15.9 0.2 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Phage_HK97_TLTM PF06120.11 EPE32398.1 - 0.026 13.7 8.4 0.053 12.7 8.4 1.5 1 1 0 1 1 1 0 Tail length tape measure protein FUN14 PF04930.15 EPE32398.1 - 0.053 13.9 0.2 0.14 12.6 0.0 1.8 2 0 0 2 2 2 0 FUN14 family HAUS6_N PF14661.6 EPE32398.1 - 0.062 12.9 4.4 0.6 9.7 0.2 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus MerR-DNA-bind PF09278.11 EPE32398.1 - 4.8 7.8 9.9 0.17 12.4 1.4 2.5 2 1 1 3 3 3 0 MerR, DNA binding Tn7_TnsC_Int PF11426.8 EPE32399.1 - 0.079 13.1 3.0 1.8 8.8 0.6 2.4 2 0 0 2 2 2 0 Tn7 transposition regulator TnsC SBDS PF01172.18 EPE32400.1 - 3.1e-26 91.2 0.9 3.7e-26 91.0 0.9 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein NmrA PF05368.13 EPE32401.1 - 1.5e-64 217.8 0.0 1.8e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE32401.1 - 1.7e-16 60.7 0.0 2.5e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EPE32401.1 - 0.00011 21.3 0.2 0.00018 20.6 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EPE32401.1 - 0.006 16.8 0.1 0.013 15.8 0.1 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Peroxin-13_N PF04088.13 EPE32402.1 - 2.9e-53 180.0 0.1 4e-53 179.6 0.1 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EPE32402.1 - 2.9e-07 30.0 0.0 5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EPE32402.1 - 3.1e-07 29.9 0.0 6.4e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPE32402.1 - 9.5e-06 25.4 0.1 1.5e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain GtrA PF04138.14 EPE32403.1 - 0.01 16.1 7.2 0.023 15.0 0.8 2.2 2 0 0 2 2 2 0 GtrA-like protein MARVEL PF01284.23 EPE32403.1 - 0.069 13.2 11.9 0.38 10.8 11.2 2.0 1 1 1 2 2 2 0 Membrane-associating domain RNA_pol_Rpc34 PF05158.12 EPE32405.1 - 7.3e-90 301.7 0.0 9.2e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 EPE32405.1 - 0.038 14.7 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal MarR PF01047.22 EPE32405.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 MarR family EndIII_4Fe-2S PF10576.9 EPE32405.1 - 0.52 10.7 2.1 1 9.8 2.1 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Pro_isomerase PF00160.21 EPE32406.1 - 8.9e-42 143.0 0.1 1.2e-41 142.7 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.20 EPE32407.1 - 7.4e-46 155.3 0.1 1.1e-45 154.7 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EPE32407.1 - 0.0007 18.7 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF5102 PF17104.5 EPE32407.1 - 0.082 12.9 4.4 0.22 11.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) TPR_1 PF00515.28 EPE32408.1 - 8.8e-45 148.8 23.9 1.5e-06 27.8 1.2 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 EPE32408.1 - 4.4e-36 120.1 27.2 9.2e-05 22.3 0.6 9.8 9 1 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 EPE32408.1 - 2.6e-33 113.7 16.9 1.4e-18 66.5 3.5 3.3 3 0 0 3 3 3 2 STI1 domain TPR_8 PF13181.6 EPE32408.1 - 5.5e-23 79.2 28.5 0.00027 20.9 0.3 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 EPE32408.1 - 1.4e-21 75.9 21.5 0.00035 20.2 0.3 8.5 5 2 3 8 8 8 7 TPR repeat TPR_16 PF13432.6 EPE32408.1 - 1.2e-16 61.0 9.6 0.00017 22.1 0.2 5.9 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EPE32408.1 - 1.1e-14 54.4 16.3 6.5e-08 32.8 0.8 6.0 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EPE32408.1 - 3.5e-11 42.3 13.0 0.02 14.9 0.6 7.3 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EPE32408.1 - 5.4e-11 42.3 12.7 2.8 9.0 0.2 8.7 4 3 5 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPE32408.1 - 1.6e-10 41.4 14.1 0.00062 20.2 0.5 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EPE32408.1 - 7e-10 38.9 4.0 0.0013 18.8 0.0 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPE32408.1 - 9.8e-10 38.1 6.8 0.31 11.5 0.1 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EPE32408.1 - 7e-05 22.6 14.6 0.00022 21.0 0.5 5.7 6 1 1 7 7 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 EPE32408.1 - 0.021 14.3 0.1 11 5.6 0.1 4.0 3 0 0 3 3 3 0 SHNi-TPR TPR_6 PF13174.6 EPE32408.1 - 0.022 15.4 24.7 1.3 9.8 0.2 7.6 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 EPE32408.1 - 0.033 14.5 0.2 0.033 14.5 0.2 4.6 4 2 2 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EPE32408.1 - 0.04 14.0 9.3 15 5.8 0.0 5.8 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 EPE32408.1 - 0.094 12.7 14.6 0.14 12.2 1.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE32408.1 - 0.16 12.2 9.0 2.1 8.7 1.6 3.6 4 0 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF982 PF06169.12 EPE32408.1 - 0.93 9.6 3.4 22 5.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF982) TOM20_plant PF06552.12 EPE32408.1 - 2.1 8.1 7.4 1.1 9.0 0.3 3.3 3 0 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF357 PF04010.13 EPE32408.1 - 2.3 8.4 10.7 0.42 10.7 0.3 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF357) Trypan_PARP PF05887.11 EPE32408.1 - 2.6 8.0 19.6 0.25 11.3 14.5 1.9 2 0 0 2 2 1 0 Procyclic acidic repetitive protein (PARP) PH_6 PF15406.6 EPE32409.1 - 6.2e-43 145.6 5.4 6.2e-43 145.6 5.4 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EPE32409.1 - 1.5e-05 25.5 2.0 2.3e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 PH domain Tho2 PF11262.8 EPE32409.1 - 1.6 7.9 6.8 2.5 7.2 6.8 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Cyclase PF04199.13 EPE32412.1 - 2.5e-17 63.4 0.1 3.6e-17 62.9 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase adh_short PF00106.25 EPE32413.1 - 2.2e-45 154.5 0.0 2.8e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE32413.1 - 8.6e-31 107.3 0.0 1.1e-30 107.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE32413.1 - 1.7e-05 24.8 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EPE32413.1 - 2.1e-05 24.5 0.0 3.2e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE32413.1 - 0.022 14.2 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family tRNA-synt_2 PF00152.20 EPE32415.1 - 1.6e-65 221.3 0.0 2e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EPE32415.1 - 1.7e-05 24.4 0.0 0.0057 16.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) zf-Tim10_DDP PF02953.15 EPE32416.1 - 6.8e-20 70.5 1.7 8e-20 70.3 1.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.9 EPE32416.1 - 0.081 13.0 1.8 0.081 13.0 1.8 1.8 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase DUF1287 PF06940.11 EPE32416.1 - 0.13 12.0 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) DUF2597 PF10772.9 EPE32416.1 - 0.14 12.2 0.1 0.19 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) ADIP PF11559.8 EPE32417.1 - 0.0041 17.2 0.3 0.0092 16.1 0.3 1.6 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding PG_binding_1 PF01471.18 EPE32417.1 - 0.0091 16.2 0.0 1.1 9.5 0.0 3.0 2 0 0 2 2 2 1 Putative peptidoglycan binding domain BLOC1_2 PF10046.9 EPE32417.1 - 0.033 14.5 2.0 0.053 13.8 1.1 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 EPE32417.1 - 0.078 13.5 0.4 19 5.8 0.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF812 PF05667.11 EPE32417.1 - 0.14 11.0 3.6 0.23 10.3 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fungal_trans_2 PF11951.8 EPE32417.1 - 0.17 10.7 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Laminin_II PF06009.12 EPE32417.1 - 0.27 11.2 2.1 2.8 8.0 0.8 2.4 1 1 1 2 2 2 0 Laminin Domain II FPP PF05911.11 EPE32417.1 - 0.32 9.2 3.3 0.45 8.6 3.3 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF1664 PF07889.12 EPE32417.1 - 0.95 9.5 4.5 0.57 10.2 1.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 EPE32417.1 - 1.4 8.3 9.9 0.46 9.9 6.4 1.8 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 EPE32417.1 - 2 7.2 5.9 3.8 6.3 5.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 EPE32417.1 - 4.3 7.5 9.7 0.11 12.6 2.7 2.0 2 0 0 2 2 2 0 Tropomyosin like ZapB PF06005.12 EPE32417.1 - 6.9 7.2 6.1 3.4 8.2 1.7 2.5 1 1 1 2 2 2 0 Cell division protein ZapB CLTH PF10607.9 EPE32418.1 - 5e-31 107.6 0.0 9.7e-31 106.7 0.0 1.5 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EPE32418.1 - 1.4e-07 31.5 0.1 2.4e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 EPE32418.1 - 0.00048 19.6 0.0 0.00069 19.1 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 EPE32418.1 - 0.0047 16.9 0.1 0.0079 16.1 0.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EPE32418.1 - 0.0049 17.2 0.3 0.0081 16.5 0.3 1.4 1 0 0 1 1 1 1 Ring finger domain KxDL PF10241.9 EPE32418.1 - 0.0095 16.2 0.1 3.7 7.9 0.3 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein Prok-RING_4 PF14447.6 EPE32418.1 - 0.017 15.0 0.5 0.031 14.1 0.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EPE32418.1 - 0.03 14.2 0.7 0.052 13.4 0.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPE32418.1 - 0.058 13.3 0.2 0.097 12.5 0.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SH3BP5 PF05276.14 EPE32418.1 - 0.081 12.7 0.1 5.9 6.6 0.0 2.3 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) zf-C3HC4 PF00097.25 EPE32418.1 - 0.1 12.5 0.3 0.18 11.7 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PPP4R2 PF09184.11 EPE32419.1 - 1.4e-06 28.1 2.7 1.8e-06 27.8 0.0 2.2 2 1 1 3 3 3 1 PPP4R2 ECH_1 PF00378.20 EPE32422.1 - 1.5e-38 132.6 0.0 1.7e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPE32422.1 - 1.1e-18 67.9 0.2 1.6e-18 67.3 0.2 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ribonuc_L-PSP PF01042.21 EPE32423.1 - 5.1e-39 133.0 0.0 5.7e-39 132.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP End_N_terminal PF12218.8 EPE32424.1 - 0.045 13.4 0.0 0.58 9.9 0.0 2.3 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase GATA PF00320.27 EPE32425.1 - 5.9e-16 57.8 5.4 1.1e-15 57.0 5.4 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 EPE32425.1 - 2.4e-15 56.6 0.0 4.7e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EPE32425.1 - 1.6e-11 44.2 0.0 3.8e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EPE32425.1 - 7.9e-09 35.7 0.0 2.5e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EPE32425.1 - 8.9e-07 29.1 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 EPE32425.1 - 1.3e-05 25.3 0.0 2.3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 PAS domain Zn-ribbon_8 PF09723.10 EPE32425.1 - 0.011 15.8 0.2 0.021 14.9 0.2 1.4 1 0 0 1 1 1 0 Zinc ribbon domain MAGI_u5 PF16666.5 EPE32425.1 - 0.042 14.0 0.4 0.097 12.8 0.4 1.5 1 0 0 1 1 1 0 Unstructured region on MAGI DUF4428 PF14471.6 EPE32425.1 - 1.5 8.8 4.1 0.52 10.3 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) POT1 PF02765.17 EPE32426.1 - 6.1e-08 32.6 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Epimerase PF01370.21 EPE32427.1 - 4.2e-13 49.3 0.0 9.4e-13 48.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE32427.1 - 1e-05 24.7 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EPE32427.1 - 0.00013 21.5 0.2 0.00022 20.7 0.2 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPE32427.1 - 0.0011 18.2 0.2 0.019 14.2 0.3 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EPE32427.1 - 0.03 14.2 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Flavin_Reduct PF01613.18 EPE32431.1 - 6.3e-16 58.8 0.0 2.5e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 Flavin reductase like domain Vps5 PF09325.10 EPE32433.1 - 8.3e-88 293.9 6.8 8.3e-88 293.9 6.8 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 EPE32433.1 - 1.5e-23 82.9 0.0 3.6e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 PX domain BAR_3 PF16746.5 EPE32433.1 - 0.095 12.4 8.4 0.59 9.8 3.3 2.4 1 1 1 2 2 2 0 BAR domain of APPL family Med11 PF10280.9 EPE32434.1 - 3.9e-42 144.0 0.0 4.8e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein WD40 PF00400.32 EPE32435.1 - 1.3e-44 149.3 25.2 2.7e-08 34.4 0.8 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EPE32435.1 - 4.6e-40 136.9 1.3 6.5e-40 136.4 1.3 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EPE32435.1 - 1.7e-12 47.4 1.1 0.038 14.3 0.0 5.4 2 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE32435.1 - 0.00042 20.2 0.2 0.0011 18.9 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 EPE32435.1 - 0.00076 19.3 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 EPE32435.1 - 0.0019 16.9 0.0 0.73 8.4 0.0 2.5 2 0 0 2 2 2 2 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 EPE32435.1 - 0.0081 15.5 0.0 2 7.6 0.0 2.6 3 0 0 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleos_tra2_C PF07662.13 EPE32437.1 - 7.3e-72 241.5 4.1 7.3e-72 241.5 4.1 2.9 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EPE32437.1 - 1.5e-21 76.8 6.7 1.5e-21 76.8 6.7 3.6 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 EPE32437.1 - 0.00066 19.9 7.2 0.00066 19.9 7.2 3.9 4 1 1 5 5 5 1 Nucleoside recognition DUF3290 PF11694.8 EPE32437.1 - 0.061 13.3 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Abhydrolase_6 PF12697.7 EPE32438.1 - 2.7e-13 51.0 0.0 4e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE32438.1 - 1.8e-08 34.4 0.0 2.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE32438.1 - 0.0033 16.7 0.0 0.009 15.3 0.0 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 EPE32438.1 - 0.09 11.8 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) adh_short PF00106.25 EPE32439.1 - 2.8e-19 69.4 0.2 1.3e-14 54.2 0.3 2.9 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE32439.1 - 5.4e-09 35.9 0.0 8.1e-08 32.1 0.0 2.5 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE32439.1 - 3.6e-05 23.7 0.4 6.9e-05 22.8 0.4 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE32439.1 - 0.015 14.8 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EPE32439.1 - 0.059 12.7 0.1 0.12 11.7 0.1 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Clr5 PF14420.6 EPE32440.1 - 3.7e-19 68.7 5.0 7.7e-19 67.7 5.0 1.6 1 0 0 1 1 1 1 Clr5 domain DUF4969 PF16339.5 EPE32445.1 - 0.082 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) SMI1_KNR4 PF09346.10 EPE32446.1 - 2e-08 34.7 1.7 2.9e-07 30.9 1.7 2.4 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 EPE32446.1 - 2.1e-07 31.4 0.2 5e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 EPE32446.1 - 4.4e-07 29.7 1.2 0.00013 21.7 0.0 2.4 2 0 0 2 2 2 2 SMI1-KNR4 cell-wall Fasciclin PF02469.22 EPE32448.1 - 2e-47 160.6 1.4 2.6e-26 92.4 0.2 2.1 2 0 0 2 2 2 2 Fasciclin domain DUF211 PF02680.14 EPE32448.1 - 0.0064 16.6 0.4 5.7 7.2 0.1 2.5 2 0 0 2 2 2 2 Uncharacterized ArCR, COG1888 EFG_IV PF03764.18 EPE32448.1 - 0.021 14.6 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Elongation factor G, domain IV Glyco_transf_20 PF00982.21 EPE32449.1 - 2.4e-150 501.3 0.0 3.2e-150 501.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EPE32449.1 - 5.3e-71 238.4 0.0 9.8e-71 237.6 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EPE32449.1 - 0.013 15.2 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HD_assoc PF13286.6 EPE32449.1 - 0.058 13.9 0.1 0.14 12.7 0.1 1.6 1 0 0 1 1 1 0 Phosphohydrolase-associated domain DUF1819 PF08849.11 EPE32449.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) Glyco_transf_5 PF08323.11 EPE32449.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain Nnf1 PF03980.14 EPE32452.1 - 5.8e-29 100.7 0.0 8.5e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Nnf1 SlyX PF04102.12 EPE32452.1 - 0.0063 17.1 0.3 0.66 10.6 0.1 2.7 2 0 0 2 2 2 1 SlyX DUF641 PF04859.12 EPE32452.1 - 0.014 15.8 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Rab_bind PF16704.5 EPE32452.1 - 0.014 15.4 0.4 0.033 14.2 0.4 1.6 1 0 0 1 1 1 0 Rab binding domain bZIP_1 PF00170.21 EPE32452.1 - 0.058 13.5 0.4 0.13 12.4 0.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor Fib_alpha PF08702.10 EPE32452.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CAP_N PF01213.19 EPE32452.1 - 0.71 9.3 7.4 0.3 10.5 0.2 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EPE32452.1 - 6.9 6.7 9.0 0.74 9.9 0.9 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF899 PF05988.12 EPE32453.1 - 3.3e-70 236.0 0.0 4.3e-70 235.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Glyco_hydro_3_C PF01915.22 EPE32454.1 - 1.3e-48 165.7 0.0 3.2e-48 164.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE32454.1 - 2.9e-37 128.7 0.0 5.7e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE32454.1 - 1.7e-14 53.7 0.0 3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain ERG4_ERG24 PF01222.17 EPE32456.1 - 3.3e-167 556.6 5.0 3.9e-167 556.4 5.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EPE32456.1 - 0.042 13.4 0.2 0.042 13.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.15 EPE32457.1 - 1.5e-17 63.6 0.0 5e-17 61.8 0.0 1.8 1 1 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EPE32457.1 - 2.4e-15 57.1 0.0 6e-15 55.8 0.0 1.6 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EPE32457.1 - 1.1e-09 38.5 0.0 0.00086 19.4 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat FAD_binding_7 PF03441.14 EPE32458.1 - 9.1e-70 234.2 0.3 1.8e-69 233.3 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EPE32458.1 - 2.8e-36 125.0 0.1 7.7e-36 123.6 0.1 1.7 2 0 0 2 2 2 1 DNA photolyase PH_9 PF15410.6 EPE32459.1 - 0.0011 19.3 0.0 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EPE32459.1 - 0.013 16.0 0.1 0.038 14.5 0.0 1.7 2 0 0 2 2 2 0 PH domain Methyltransf_31 PF13847.6 EPE32461.1 - 5.6e-18 65.2 0.0 8.1e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE32461.1 - 5.5e-06 27.0 0.0 1.3e-05 25.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE32461.1 - 1e-05 26.2 0.0 1.6e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EPE32461.1 - 0.00045 20.2 0.0 0.00058 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE32461.1 - 0.0036 17.9 0.0 0.0075 16.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE32461.1 - 0.0092 15.8 0.0 0.029 14.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Cytochrom_B561 PF03188.16 EPE32462.1 - 6.7e-08 32.8 5.0 1.3e-07 31.8 5.0 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Phage_holin_2_4 PF16082.5 EPE32462.1 - 0.031 14.0 0.0 0.28 10.9 0.0 2.8 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF2427 PF10348.9 EPE32462.1 - 0.04 13.7 4.8 0.086 12.6 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF4079 PF13301.6 EPE32462.1 - 0.78 9.9 14.8 1.9 8.7 0.8 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) FA_desaturase PF00487.24 EPE32462.1 - 1.3 8.8 17.1 0.3 10.9 6.6 2.3 1 1 1 2 2 2 0 Fatty acid desaturase MARVEL PF01284.23 EPE32462.1 - 4.3 7.4 10.9 4.7 7.2 3.6 2.5 1 1 1 2 2 2 0 Membrane-associating domain F-box-like PF12937.7 EPE32463.1 - 0.12 12.3 4.5 1 9.3 0.0 3.0 3 0 0 3 3 3 0 F-box-like DUF4215 PF13948.6 EPE32464.1 - 8.5e-05 22.9 4.9 0.00031 21.1 4.9 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4215) zf-NADH-PPase PF09297.11 EPE32464.1 - 4.4 7.1 8.3 7.1 6.4 0.6 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain AA_permease_2 PF13520.6 EPE32465.1 - 3.6e-46 157.9 47.6 5.4e-46 157.3 47.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE32465.1 - 1.4e-20 73.4 40.6 2.9e-20 72.3 40.5 1.5 1 1 0 1 1 1 1 Amino acid permease ANAPC4 PF12896.7 EPE32466.1 - 8e-67 224.7 0.2 1.3e-66 224.1 0.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EPE32466.1 - 4.1e-32 110.3 0.0 5.8e-31 106.6 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Pik1 PF11522.8 EPE32466.1 - 0.1 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Adap_comp_sub PF00928.21 EPE32467.1 - 1.5e-18 67.1 0.1 2.3e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EPE32467.1 - 9.8e-07 28.8 0.3 1.8e-06 27.9 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 EPE32467.1 - 0.0069 16.8 0.4 0.015 15.7 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.9 EPE32468.1 - 2.8e-15 56.3 0.1 5.3e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Mg_trans_NIPA PF05653.14 EPE32469.1 - 4.2e-105 351.1 15.2 5.1e-105 350.8 15.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EPE32469.1 - 0.00012 22.2 7.0 0.00012 22.2 7.0 3.9 4 1 0 4 4 4 1 EamA-like transporter family Acyl_transf_3 PF01757.22 EPE32469.1 - 3.4 6.6 17.7 20 4.1 14.6 2.2 1 1 1 2 2 2 0 Acyltransferase family Ribosomal_S3_C PF00189.20 EPE32470.1 - 8.4e-25 87.1 0.2 4.5e-24 84.8 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EPE32470.1 - 6e-12 45.2 0.1 1.1e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 EPE32470.1 - 0.048 13.5 0.2 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Coilin N-terminus UN_NPL4 PF11543.8 EPE32470.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Myotub-related PF06602.14 EPE32472.1 - 2.9e-146 486.9 0.0 3.7e-146 486.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EPE32472.1 - 0.086 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family HEAT PF02985.22 EPE32473.1 - 1.5e-39 130.6 17.2 0.015 15.5 0.1 13.2 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 EPE32473.1 - 2.9e-38 130.1 7.6 4.1e-11 43.1 0.0 8.5 3 3 6 9 9 9 9 HEAT repeats HEAT_EZ PF13513.6 EPE32473.1 - 9.3e-14 51.6 6.2 0.0045 17.5 0.0 8.1 8 2 2 10 10 10 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EPE32473.1 - 2.6e-11 44.0 5.1 0.0052 17.4 0.1 7.8 4 1 5 9 9 9 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EPE32473.1 - 4.1e-11 43.2 10.1 0.00091 19.3 0.1 6.5 4 1 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EPE32473.1 - 1.3e-07 30.6 6.5 4.2e-05 22.3 1.9 4.9 2 1 1 4 4 4 3 Adaptin N terminal region RTP1_C1 PF10363.9 EPE32473.1 - 6.5e-06 26.3 5.2 0.28 11.4 0.1 5.0 4 1 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Proteasom_PSMB PF10508.9 EPE32473.1 - 0.00039 19.1 4.4 0.13 10.8 1.1 2.4 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit CLASP_N PF12348.8 EPE32473.1 - 0.005 16.4 2.2 2 7.9 0.1 4.1 2 2 2 4 4 4 2 CLASP N terminal Arm PF00514.23 EPE32473.1 - 0.0059 16.6 3.6 3.3 7.9 0.0 4.8 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat TetR_C_16 PF17920.1 EPE32473.1 - 0.036 14.3 0.5 19 5.5 0.1 4.1 2 1 2 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Ecm29 PF13001.7 EPE32473.1 - 0.12 11.0 4.7 3.3 6.3 0.1 4.0 4 1 0 5 5 5 0 Proteasome stabiliser M11L PF11099.8 EPE32473.1 - 0.12 12.6 0.1 22 5.3 0.0 3.2 2 1 1 3 3 3 0 Apoptosis regulator M11L like API5 PF05918.11 EPE32473.1 - 10 4.8 7.6 2.6 6.7 0.3 3.4 3 1 1 4 4 4 0 Apoptosis inhibitory protein 5 (API5) tRNA_synthFbeta PF17759.1 EPE32474.1 - 1.4e-44 152.1 0.0 2.1e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EPE32474.1 - 1.3e-27 95.8 0.1 2e-24 85.6 0.0 3.4 2 1 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EPE32474.1 - 6.8e-26 91.0 0.0 1.2e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EPE32474.1 - 2.5e-17 62.9 0.0 1.5e-15 57.3 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain Caprin-1_dimer PF18293.1 EPE32476.1 - 0.099 13.1 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Caprin-1 dimerization domain MIP PF00230.20 EPE32478.1 - 9.4e-48 162.9 13.3 1.2e-47 162.5 13.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein Zn_clus PF00172.18 EPE32479.1 - 0.0016 18.6 23.7 0.0074 16.4 6.1 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPE32480.1 - 3.4e-18 65.7 54.2 3.5e-13 49.2 23.0 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EPE32480.1 - 7.5e-12 44.5 14.6 2.3e-11 42.9 14.6 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.28 EPE32481.1 - 2.4e-24 85.7 0.0 3.4e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.15 EPE32481.1 - 3.2e-08 32.7 0.0 0.00036 19.3 0.0 2.9 3 0 0 3 3 3 2 Transferase family PP-binding PF00550.25 EPE32481.1 - 4.4e-07 30.1 0.0 9.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site DIT1_PvcA PF05141.12 EPE32483.1 - 3.4e-93 312.1 0.0 5e-93 311.6 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein ABC2_membrane PF01061.24 EPE32483.1 - 1.4e-85 286.0 55.6 3.1e-46 157.5 24.2 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EPE32483.1 - 5.5e-33 114.4 0.0 1.8e-15 57.7 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EPE32483.1 - 2e-32 110.9 9.4 4.1e-31 106.7 0.0 3.6 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EPE32483.1 - 1e-16 61.3 0.0 2.1e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal DJ-1_PfpI PF01965.24 EPE32483.1 - 4.5e-12 46.1 0.0 8.1e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ABC2_membrane_3 PF12698.7 EPE32483.1 - 1.6e-05 24.2 34.4 3.9e-05 22.9 4.5 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EPE32483.1 - 6.8e-05 22.8 0.1 0.0086 16.0 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EPE32483.1 - 7.5e-05 23.2 0.1 0.41 11.0 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.6 EPE32483.1 - 0.00012 21.8 0.0 0.00055 19.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EPE32483.1 - 0.0014 19.2 0.0 0.041 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EPE32483.1 - 0.0023 17.6 1.9 0.13 12.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EPE32483.1 - 0.01 16.1 0.2 2.7 8.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EPE32483.1 - 0.014 15.5 0.0 0.47 10.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EPE32483.1 - 0.016 14.7 0.0 0.37 10.2 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EPE32483.1 - 0.056 13.3 6.5 7.3 6.3 0.0 3.9 2 2 2 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EPE32483.1 - 0.065 13.3 0.0 17 5.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.19 EPE32483.1 - 0.081 12.5 1.2 0.89 9.1 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EPE32483.1 - 0.1 12.3 1.1 5.3 6.7 0.2 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EPE32483.1 - 0.19 11.6 1.0 9.8 6.1 0.2 2.8 2 0 0 2 2 2 0 NACHT domain Methyltransf_2 PF00891.18 EPE32484.1 - 2e-20 73.0 0.0 3.9e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EPE32484.1 - 0.0021 18.8 0.0 0.0049 17.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE32484.1 - 0.0056 17.4 0.0 0.023 15.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EPE32484.1 - 0.012 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 EPE32484.1 - 0.051 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase GidB PF02527.15 EPE32484.1 - 0.08 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF938 PF06080.12 EPE32484.1 - 0.11 12.2 0.0 0.39 10.5 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF938) CheR PF01739.18 EPE32484.1 - 0.17 11.3 0.0 2.8 7.4 0.0 2.1 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain DUF608 PF04685.13 EPE32484.1 - 0.17 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region T5orf172 PF10544.9 EPE32485.1 - 5.8e-15 55.7 0.5 1.5e-14 54.4 0.1 1.9 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 EPE32485.1 - 2.4e-10 41.0 0.1 2.4e-10 41.0 0.1 1.9 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 NmrA PF05368.13 EPE32486.1 - 4.3e-12 46.1 0.1 1.1e-05 25.2 0.1 2.2 1 1 1 2 2 2 2 NmrA-like family Sacchrp_dh_NADP PF03435.18 EPE32486.1 - 0.0091 16.3 0.1 0.044 14.0 0.0 2.3 3 1 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EPE32486.1 - 0.025 15.0 0.0 0.082 13.3 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GIT_SHD PF08518.11 EPE32486.1 - 0.17 11.5 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT ADH_zinc_N PF00107.26 EPE32488.1 - 8.5e-26 90.5 0.5 1.9e-25 89.4 0.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE32488.1 - 1.1e-16 62.1 0.1 3.3e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE32488.1 - 7.9e-10 38.6 0.1 1.3e-08 34.6 0.1 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EPE32488.1 - 0.092 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase TIG PF01833.24 EPE32489.1 - 0.005 16.9 0.1 0.013 15.6 0.1 1.7 1 0 0 1 1 1 1 IPT/TIG domain Hint_2 PF13403.6 EPE32489.1 - 0.03 14.6 0.6 4 7.7 0.0 3.1 3 0 0 3 3 3 0 Hint domain Mem_trans PF03547.18 EPE32490.1 - 4e-19 68.3 0.0 5.9e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Membrane transport protein TRAM_LAG1_CLN8 PF03798.16 EPE32490.1 - 0.14 11.9 2.5 0.16 11.7 0.3 2.0 2 0 0 2 2 2 0 TLC domain NapE PF06796.11 EPE32490.1 - 0.36 10.4 0.0 0.36 10.4 0.0 3.3 4 0 0 4 4 4 0 Periplasmic nitrate reductase protein NapE DUF5423 PF17461.2 EPE32490.1 - 0.81 8.5 3.4 1.1 8.1 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5423) Hydrophobin_2 PF06766.11 EPE32491.1 - 2.2e-23 82.0 9.7 2.8e-23 81.6 9.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin CPL PF08144.11 EPE32492.1 - 4.4e-36 124.4 6.3 7.9e-36 123.5 0.0 4.1 5 2 0 6 6 6 1 CPL (NUC119) domain MAP65_ASE1 PF03999.12 EPE32492.1 - 0.0028 16.4 9.4 0.0053 15.5 9.4 1.4 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) RWD PF05773.22 EPE32493.1 - 7.3e-24 84.3 0.2 1.3e-23 83.5 0.2 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 EPE32493.1 - 1.7e-05 25.2 8.7 2.4e-05 24.7 7.7 1.8 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 Phage_B PF02304.15 EPE32493.1 - 0.019 15.4 0.3 0.031 14.7 0.3 1.3 1 0 0 1 1 1 0 Scaffold protein B TPR_2 PF07719.17 EPE32494.1 - 4.1e-10 39.0 0.0 0.00097 19.1 0.0 5.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPE32494.1 - 1.8e-08 34.0 0.0 6.3e-05 22.9 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EPE32494.1 - 2.4e-08 34.4 6.2 0.0088 16.5 0.4 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EPE32494.1 - 6.4e-08 32.3 5.8 2.1e-05 24.0 2.1 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 EPE32494.1 - 1.3e-07 31.8 6.6 1.6 9.8 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EPE32494.1 - 2.1e-07 31.1 4.4 0.0007 19.8 0.3 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EPE32494.1 - 1.3e-06 28.0 1.8 0.052 13.6 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EPE32494.1 - 3.2e-06 26.7 0.0 0.0073 16.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPE32494.1 - 9.9e-05 22.9 12.4 0.012 16.3 0.5 5.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EPE32494.1 - 0.0021 17.9 10.5 0.6 10.1 0.1 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPE32494.1 - 0.023 15.1 0.0 25 5.6 0.0 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPE32494.1 - 0.028 15.0 2.3 36 5.3 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SpmSyn_N PF17950.1 EPE32494.1 - 0.049 13.8 0.0 9.4 6.5 0.0 2.4 2 0 0 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal HrpB1_HrpK PF09613.10 EPE32494.1 - 0.11 12.2 1.9 0.31 10.7 0.1 2.7 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_11 PF13414.6 EPE32494.1 - 0.32 10.7 2.5 0.69 9.6 0.1 2.9 5 0 0 5 5 5 0 TPR repeat TPR_4 PF07721.14 EPE32494.1 - 3.1 8.7 9.6 19 6.2 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat FAM110_C PF14160.6 EPE32495.1 - 1.4 10.0 6.1 1.4 10.0 0.9 2.4 2 1 0 2 2 2 0 Centrosome-associated C terminus Rad51 PF08423.11 EPE32497.1 - 4.6e-129 429.1 0.0 5.7e-129 428.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EPE32497.1 - 4.1e-09 36.3 0.0 6.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 EPE32497.1 - 2.9e-08 33.5 0.0 4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EPE32497.1 - 5e-06 27.0 0.4 1.8e-05 25.2 0.2 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 EPE32497.1 - 2.4e-05 23.8 0.2 6.5e-05 22.4 0.2 1.8 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 EPE32497.1 - 0.032 13.6 0.1 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 EPE32497.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 EPE32497.1 - 0.11 12.5 0.1 0.63 10.1 0.1 2.1 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain PAXNEB PF05625.11 EPE32497.1 - 0.14 11.2 1.8 0.79 8.8 0.6 2.0 1 1 1 2 2 2 0 PAXNEB protein Nup160 PF11715.8 EPE32498.1 - 3.7e-128 428.5 0.2 4.7e-128 428.2 0.2 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 DUF5331 PF17265.2 EPE32498.1 - 0.13 12.0 0.0 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5331) Vps26 PF03643.15 EPE32499.1 - 1e-123 411.7 0.4 1.2e-123 411.5 0.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EPE32499.1 - 0.00039 20.5 0.8 0.18 11.9 0.7 3.8 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain IL17R_D_N PF16742.5 EPE32499.1 - 0.17 11.9 0.1 0.33 11.0 0.1 1.4 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D PAT1 PF09770.9 EPE32500.1 - 0 1264.6 0.1 0 1264.4 0.1 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF746 PF05344.11 EPE32500.1 - 0.037 13.9 0.0 0.091 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) DUF3533 PF12051.8 EPE32501.1 - 2.1e-119 398.8 14.2 2.4e-119 398.6 14.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF1524 PF07510.11 EPE32502.1 - 1.1e-07 31.9 0.0 1.2e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 EPE32502.1 - 0.11 12.5 0.4 0.33 10.9 0.4 1.8 1 1 0 1 1 1 0 HNH endonuclease WD40 PF00400.32 EPE32504.1 - 2.6e-28 97.7 8.2 3.5e-06 27.6 0.4 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE32504.1 - 2e-06 28.0 0.1 0.17 12.2 0.0 4.4 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPE32504.1 - 1.2e-05 24.1 5.7 0.31 9.6 0.0 5.0 3 2 1 5 5 5 3 Nucleoporin Nup120/160 DUF5046 PF16465.5 EPE32504.1 - 0.0062 16.0 0.6 0.29 10.6 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5046) DUF724 PF05266.14 EPE32504.1 - 0.11 12.3 3.6 0.24 11.2 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4600 PF15372.6 EPE32504.1 - 0.85 10.1 5.9 4.7 7.7 6.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) APG6_N PF17675.1 EPE32504.1 - 1.8 9.1 12.9 9.1 6.8 12.7 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region BCIP PF13862.6 EPE32506.1 - 3.3e-72 242.6 0.1 4.2e-72 242.3 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein GMP_synt_C PF00958.22 EPE32507.1 - 8.4e-41 137.9 0.0 1.8e-40 136.9 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EPE32507.1 - 3.1e-37 128.2 0.0 5.2e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EPE32507.1 - 6.8e-11 41.7 0.1 4.2e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EPE32507.1 - 3.3e-08 33.6 0.1 6e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 EPE32507.1 - 0.0007 18.5 0.1 0.0021 16.9 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 EPE32507.1 - 0.001 18.6 0.0 0.0047 16.4 0.0 1.9 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 EPE32507.1 - 0.0044 16.6 0.0 0.0086 15.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.19 EPE32507.1 - 0.028 13.7 0.1 0.046 13.0 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.19 EPE32507.1 - 0.069 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 EPE32507.1 - 0.15 11.8 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 PP-loop family SH3_1 PF00018.28 EPE32508.1 - 0.0003 20.3 0.6 0.00066 19.2 0.6 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPE32508.1 - 0.00038 20.2 0.1 0.00092 19.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain VSP PF03302.13 EPE32508.1 - 0.001 18.0 17.1 0.0016 17.4 17.1 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein CYYR1 PF10873.8 EPE32508.1 - 0.0023 18.4 0.0 0.0076 16.7 0.0 2.0 1 0 0 1 1 1 1 Cysteine and tyrosine-rich protein 1 DUF4690 PF15756.5 EPE32508.1 - 0.048 14.3 3.9 0.056 14.0 0.9 2.6 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Podoplanin PF05808.11 EPE32508.1 - 0.061 13.4 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Podoplanin Syndecan PF01034.20 EPE32508.1 - 0.19 11.7 0.2 0.37 10.7 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain Pkinase PF00069.25 EPE32510.1 - 6.5e-23 81.4 0.0 1.3e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EPE32510.1 - 1.4e-07 32.1 12.1 0.0011 19.7 0.6 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT PF02985.22 EPE32510.1 - 4.9e-07 29.5 1.0 2.8 8.4 0.1 6.1 6 0 0 6 6 6 2 HEAT repeat Pkinase_Tyr PF07714.17 EPE32510.1 - 7.6e-06 25.4 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE32510.1 - 0.017 14.5 0.0 0.033 13.5 0.0 1.5 1 1 0 1 1 1 0 Kinase-like HEAT_2 PF13646.6 EPE32510.1 - 0.021 15.2 1.0 8.5 6.8 0.0 3.8 4 0 0 4 4 4 0 HEAT repeats LRR_9 PF14580.6 EPE32511.1 - 7.5e-55 185.1 0.1 7.5e-55 185.1 0.1 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 EPE32511.1 - 1.5e-08 34.3 1.8 1.5e-08 34.3 1.8 1.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EPE32511.1 - 9.4e-07 29.1 1.8 9.4e-07 29.1 1.8 2.4 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) T4_Gp59_C PF08994.10 EPE32511.1 - 0.011 16.3 0.0 0.022 15.4 0.0 1.5 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term HMG_box_5 PF14887.6 EPE32511.1 - 0.11 12.5 0.5 0.21 11.6 0.5 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 PspB PF06667.12 EPE32511.1 - 0.19 11.8 0.6 0.44 10.6 0.6 1.5 1 0 0 1 1 1 0 Phage shock protein B CBFD_NFYB_HMF PF00808.23 EPE32512.1 - 2.5e-08 34.1 0.3 3.9e-08 33.5 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Voltage_CLC PF00654.20 EPE32513.1 - 1.3e-87 294.3 27.2 1.3e-87 294.3 27.2 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel Glyco_hydro_43 PF04616.14 EPE32513.1 - 1.6e-63 214.7 1.9 2.5e-63 214.1 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBS PF00571.28 EPE32513.1 - 1.8e-10 41.1 0.0 0.00011 22.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain C2 PF00168.30 EPE32513.1 - 1.5e-08 34.8 0.0 3.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain GH43_C2 PF17851.1 EPE32513.1 - 1.4e-06 28.1 0.0 3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Lactonase PF10282.9 EPE32514.1 - 3.4e-62 210.7 0.0 4.7e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Kelch_5 PF13854.6 EPE32515.1 - 3.4e-16 58.8 16.7 1.1e-08 34.8 0.1 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EPE32515.1 - 5.2e-11 42.4 13.2 0.00049 20.3 0.1 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 EPE32515.1 - 1.2e-10 41.2 9.4 0.001 19.1 0.6 6.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 EPE32515.1 - 1.1e-09 38.3 12.3 0.04 14.2 0.0 6.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 EPE32515.1 - 3.3e-08 33.0 7.6 0.014 15.0 0.6 5.0 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 EPE32515.1 - 4.8e-08 32.7 1.3 0.0068 16.3 0.3 4.2 3 0 0 3 3 3 2 Kelch motif SKG6 PF08693.10 EPE32515.1 - 0.07 12.6 0.2 0.2 11.1 0.2 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Cytochrom_C_2 PF01322.20 EPE32516.1 - 0.4 11.6 4.8 0.46 11.4 0.4 2.1 1 1 1 2 2 2 0 Cytochrome C' COX14 PF14880.6 EPE32517.1 - 7.7e-19 67.3 0.2 1.7e-18 66.2 0.2 1.6 1 0 0 1 1 1 1 Cytochrome oxidase c assembly DUF4483 PF14825.6 EPE32517.1 - 0.051 13.3 0.5 0.095 12.5 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) DUF2458 PF10454.9 EPE32518.1 - 1.2e-65 220.4 0.9 1.6e-65 220.0 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) COG6 PF06419.11 EPE32518.1 - 0.025 12.8 0.0 0.03 12.6 0.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Phage_pRha PF09669.10 EPE32518.1 - 0.2 12.3 3.0 4.5 7.9 3.0 2.5 1 1 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) Thiolase_N PF00108.23 EPE32519.1 - 1.5e-74 250.6 0.5 2.1e-74 250.2 0.5 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EPE32519.1 - 7.5e-40 135.4 0.7 1.8e-39 134.2 0.7 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EPE32519.1 - 0.0011 18.7 0.9 0.0011 18.7 0.9 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EPE32519.1 - 1.3 8.9 3.8 5.3 7.0 0.1 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DAHP_synth_1 PF00793.20 EPE32521.1 - 9.6e-104 346.1 0.2 1.2e-103 345.8 0.2 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Aldo_ket_red PF00248.21 EPE32522.1 - 4.1e-62 210.0 0.0 5.3e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family S1_2 PF13509.6 EPE32523.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 S1 domain zf-C3HC4_3 PF13920.6 EPE32523.1 - 0.69 9.8 8.0 0.85 9.5 2.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Med19 PF10278.9 EPE32523.1 - 3 7.7 11.1 0.99 9.3 5.8 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 zf-MYND PF01753.18 EPE32524.1 - 1.2e-10 41.2 11.8 3.1e-10 40.0 11.8 1.7 1 0 0 1 1 1 1 MYND finger DUF3844 PF12955.7 EPE32524.1 - 0.2 11.8 8.7 0.61 10.2 4.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3844) ADH_N PF08240.12 EPE32525.1 - 4.1e-27 94.2 1.9 7.1e-27 93.4 1.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE32525.1 - 6.2e-08 32.7 0.7 1.5e-07 31.4 0.8 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.14 EPE32525.1 - 0.0011 17.8 1.5 0.0055 15.5 0.3 2.0 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EPE32525.1 - 0.0094 15.3 0.4 0.017 14.4 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 EPE32525.1 - 0.03 13.8 0.0 0.069 12.6 0.0 1.5 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus DAO PF01266.24 EPE32525.1 - 0.089 12.4 0.3 0.16 11.6 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ADH_N_assoc PF13823.6 EPE32525.1 - 0.099 12.6 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated ABM PF03992.16 EPE32526.1 - 9.3e-09 35.3 0.0 1.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3804 PF12707.7 EPE32526.1 - 0.12 12.2 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) SNARE_assoc PF09335.11 EPE32527.1 - 8.5e-19 68.2 7.9 8.5e-19 68.2 7.9 2.2 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF3278 PF11683.8 EPE32527.1 - 0.0012 18.9 1.3 0.0012 18.9 1.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3278) YrhC PF14143.6 EPE32527.1 - 0.19 11.8 2.8 0.25 11.5 1.0 2.2 2 0 0 2 2 2 0 YrhC-like protein MFS_1 PF07690.16 EPE32528.1 - 8.4e-34 117.0 59.9 1.2e-24 86.9 36.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE32528.1 - 0.00086 18.3 43.5 0.008 15.1 16.4 2.8 1 1 2 3 3 3 3 Sugar (and other) transporter Fungal_trans PF04082.18 EPE32529.1 - 5e-07 29.0 0.0 7.8e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_A_type_inc PF04508.12 EPE32529.1 - 0.05 13.5 0.1 0.42 10.6 0.0 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat RhoGAP PF00620.27 EPE32529.1 - 0.12 12.2 0.1 1.5 8.6 0.0 2.5 3 0 0 3 3 3 0 RhoGAP domain Vma12 PF11712.8 EPE32530.1 - 2.1e-45 154.2 0.0 3.2e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase GT87 PF09594.10 EPE32530.1 - 0.012 15.4 0.7 0.017 14.9 0.7 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 87 polyprenyl_synt PF00348.17 EPE32531.1 - 4.1e-73 245.6 0.0 7.5e-73 244.7 0.0 1.4 1 1 0 1 1 1 1 Polyprenyl synthetase DUF3659 PF12396.8 EPE32531.1 - 0.1 12.6 0.0 5.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) MFS_1 PF07690.16 EPE32533.1 - 2.7e-35 122.0 49.9 2.5e-25 89.1 29.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPE32533.1 - 1.6e-08 33.5 23.9 2.3e-05 23.1 4.2 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.7 EPE32533.1 - 2.1e-07 30.1 16.5 1.2e-05 24.4 4.9 2.1 2 0 0 2 2 2 2 MFS_1 like family DHDPS PF00701.22 EPE32535.1 - 1.2e-33 116.1 0.0 1.8e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Toxin_ToxA PF11584.8 EPE32535.1 - 0.035 14.1 0.0 0.07 13.1 0.0 1.5 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA Eno-Rase_NADH_b PF12242.8 EPE32535.1 - 0.088 12.6 0.0 3 7.7 0.0 2.5 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Amidase PF01425.21 EPE32536.1 - 5.7e-86 289.3 3.2 7.7e-86 288.8 3.2 1.2 1 0 0 1 1 1 1 Amidase DUF881 PF05949.12 EPE32536.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) Amidase PF01425.21 EPE32537.1 - 1.3e-65 222.1 0.0 5e-65 220.2 0.0 1.8 1 1 0 1 1 1 1 Amidase Acetyltransf_9 PF13527.7 EPE32537.1 - 2.3e-06 27.7 0.0 3.9e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE32537.1 - 3e-06 27.6 0.1 6.1e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE32537.1 - 1.2e-05 25.5 0.0 2.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE32537.1 - 8e-05 22.6 0.0 0.00022 21.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SidE PF12252.8 EPE32537.1 - 0.26 8.8 0.1 0.36 8.3 0.1 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein Fungal_trans PF04082.18 EPE32538.1 - 3.3e-21 75.5 0.2 8.2e-21 74.2 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE32538.1 - 0.00068 19.7 9.1 0.0012 18.9 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.20 EPE32539.1 - 6.5e-51 173.7 1.0 1.3e-50 172.8 1.0 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EPE32539.1 - 2.6e-20 73.3 0.0 4.5e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Stevor PF17410.2 EPE32540.1 - 0.7 9.4 6.2 0.94 9.0 6.2 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DHHW PF14286.6 EPE32540.1 - 3.8 6.7 6.6 5 6.3 6.6 1.1 1 0 0 1 1 1 0 DHHW protein Ribosomal_L50 PF10501.9 EPE32541.1 - 2.2e-13 50.3 1.0 3.4e-13 49.7 0.2 1.8 2 0 0 2 2 2 1 Ribosomal subunit 39S Blt1_C PF17183.4 EPE32541.1 - 3 7.5 5.0 1.8 8.3 0.3 2.7 3 0 0 3 3 3 0 Get5 carboxyl domain Ivy PF08816.11 EPE32542.1 - 0.12 12.6 0.3 0.17 12.1 0.3 1.2 1 0 0 1 1 1 0 Inhibitor of vertebrate lysozyme (Ivy) SIR2 PF02146.17 EPE32543.1 - 2.9e-25 89.2 0.0 9.2e-25 87.6 0.0 1.8 1 1 0 1 1 1 1 Sir2 family Med16 PF11635.8 EPE32544.1 - 4.1e-89 299.5 0.0 5.2e-89 299.1 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 EPE32544.1 - 0.021 15.1 0.0 1.2 9.5 0.0 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SNF2_N PF00176.23 EPE32545.1 - 2.5e-55 187.6 0.0 3.9e-55 187.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.6 EPE32545.1 - 1.5e-24 86.3 0.0 4.7e-24 84.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Chromo PF00385.24 EPE32545.1 - 6.3e-24 83.6 10.6 2.7e-16 59.2 0.1 4.2 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EPE32545.1 - 5.5e-19 68.6 0.0 1.5e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE32545.1 - 5.8e-08 32.9 0.8 7.5e-07 29.3 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EPE32545.1 - 6e-08 32.2 0.1 6e-08 32.2 0.1 3.2 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Cdh1_DBD_1 PF18196.1 EPE32545.1 - 1.5e-06 28.5 7.1 4.9e-06 26.9 1.8 5.4 4 1 1 5 5 5 2 Chromodomain helicase DNA-binding domain 1 SLIDE PF09111.10 EPE32545.1 - 0.00083 19.4 2.0 0.0045 17.0 0.0 3.2 2 0 0 2 2 2 1 SLIDE CHDCT2 PF08074.11 EPE32545.1 - 0.051 13.7 0.0 0.051 13.7 0.0 3.0 4 0 0 4 4 4 0 CHDCT2 (NUC038) domain ABC_tran PF00005.27 EPE32546.1 - 6.3e-35 120.7 0.0 3e-16 60.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 EPE32546.1 - 1.4e-13 50.4 4.4 1.4e-13 50.4 4.4 2.1 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 EPE32546.1 - 8.6e-11 41.7 0.9 0.003 17.0 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EPE32546.1 - 1.9e-09 37.8 6.2 0.15 11.9 1.9 4.5 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EPE32546.1 - 4e-05 23.9 0.0 0.0065 16.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EPE32546.1 - 7.8e-05 22.6 0.0 0.53 10.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Rad17 PF03215.15 EPE32546.1 - 9.4e-05 22.4 0.1 0.02 14.8 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 EPE32546.1 - 9.6e-05 22.8 0.1 0.064 13.7 0.1 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EPE32546.1 - 9.8e-05 22.2 0.2 0.47 10.1 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain Fer4 PF00037.27 EPE32546.1 - 0.00012 21.8 2.5 0.00012 21.8 2.5 2.6 3 0 0 3 3 2 1 4Fe-4S binding domain AAA_16 PF13191.6 EPE32546.1 - 0.00016 22.1 0.0 0.44 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 EPE32546.1 - 0.00035 20.4 0.1 0.2 11.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EPE32546.1 - 0.0011 19.5 0.5 0.31 11.5 0.1 2.7 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 EPE32546.1 - 0.0014 18.3 0.5 1.5 8.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 EPE32546.1 - 0.0015 18.8 0.1 1.3 9.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Fer4_6 PF12837.7 EPE32546.1 - 0.0024 17.9 10.9 0.0031 17.5 2.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 EPE32546.1 - 0.004 17.3 11.5 0.0081 16.3 11.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain SRP54 PF00448.22 EPE32546.1 - 0.0042 16.7 1.1 0.25 11.0 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_13 PF13166.6 EPE32546.1 - 0.0049 15.6 0.0 0.014 14.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EPE32546.1 - 0.0063 16.7 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EPE32546.1 - 0.0078 16.8 0.1 2.6 8.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 EPE32546.1 - 0.018 15.2 1.8 0.018 15.2 1.8 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain NB-ARC PF00931.22 EPE32546.1 - 0.021 14.1 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 EPE32546.1 - 0.026 14.5 0.1 0.32 11.0 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EPE32546.1 - 0.031 14.2 1.4 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Fer4_7 PF12838.7 EPE32546.1 - 0.04 14.5 1.3 0.04 14.5 1.3 2.4 1 1 0 2 2 2 0 4Fe-4S dicluster domain AAA_30 PF13604.6 EPE32546.1 - 0.049 13.3 0.2 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 EPE32546.1 - 0.059 13.0 0.2 24 4.5 0.1 3.1 3 0 0 3 3 3 0 Thymidylate kinase Fer4_16 PF13484.6 EPE32546.1 - 0.068 14.1 0.3 0.068 14.1 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_28 PF13521.6 EPE32546.1 - 0.085 13.1 0.2 3.9 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EPE32546.1 - 0.096 12.1 0.0 0.96 8.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 EPE32546.1 - 0.11 12.5 0.2 4.7 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_9 PF13187.6 EPE32546.1 - 0.12 12.5 11.5 0.27 11.4 11.5 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain VirE PF05272.11 EPE32546.1 - 0.13 12.0 0.0 6.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E ATPase PF06745.13 EPE32546.1 - 0.16 11.3 0.1 0.34 10.2 0.1 1.5 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.9 EPE32546.1 - 0.21 11.3 1.7 0.44 10.3 0.0 2.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EPE32546.1 - 0.21 11.1 0.6 2.9 7.4 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EPE32546.1 - 0.34 10.8 1.2 12 5.7 0.1 2.6 2 0 0 2 2 2 0 NTPase Fer4_8 PF13183.6 EPE32546.1 - 0.36 11.3 6.9 0.27 11.7 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 EPE32546.1 - 3.5 7.9 9.6 0.19 11.9 1.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain FF PF01846.19 EPE32547.1 - 9.5e-53 176.2 22.9 3.2e-16 59.2 1.2 6.9 6 1 0 6 6 6 6 FF domain WW PF00397.26 EPE32547.1 - 2.3e-17 62.8 8.2 1.5e-09 37.8 0.2 2.6 2 0 0 2 2 2 2 WW domain Lipin_mid PF16876.5 EPE32547.1 - 0.071 13.3 2.8 5 7.3 1.8 2.9 1 1 1 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain RhoGAP-FF1 PF16512.5 EPE32547.1 - 0.24 12.1 0.1 0.24 12.1 0.1 4.6 3 1 2 5 5 5 0 p190-A and -B Rho GAPs FF domain Trs65 PF12735.7 EPE32548.1 - 3.8e-116 387.9 0.2 6.3e-116 387.2 0.2 1.4 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Glycophorin_A PF01102.18 EPE32549.1 - 0.045 14.0 1.4 0.12 12.7 1.4 1.8 1 1 0 1 1 1 0 Glycophorin A DUF4690 PF15756.5 EPE32549.1 - 3.4 8.3 7.1 0.34 11.5 1.3 2.4 3 0 0 3 3 3 0 Small Novel Rich in Cartilage Glyco_hydro_18 PF00704.28 EPE32551.1 - 1.2e-58 199.4 0.0 1.7e-58 198.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EPE32551.1 - 7.5e-07 29.5 51.0 4.7e-06 27.0 10.1 3.8 3 0 0 3 3 3 2 Chitin recognition protein Chitin_bind_1 PF00187.19 EPE32552.1 - 0.019 15.5 21.3 0.019 15.5 21.3 3.3 3 0 0 3 3 3 0 Chitin recognition protein LysM PF01476.20 EPE32552.1 - 0.045 13.8 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 LysM domain ZapB PF06005.12 EPE32554.1 - 0.041 14.3 6.6 1.1 9.7 0.5 2.4 1 1 1 2 2 2 0 Cell division protein ZapB Allexi_40kDa PF05549.11 EPE32554.1 - 0.11 12.0 3.8 0.24 10.9 0.1 2.3 2 1 0 2 2 2 0 Allexivirus 40kDa protein DUF5093 PF17011.5 EPE32555.1 - 2 8.7 4.2 0.96 9.7 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5093) DUF3328 PF11807.8 EPE32557.1 - 6.3e-35 120.9 3.9 7.3e-34 117.5 3.9 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EPE32558.1 - 3.1e-15 56.6 5.5 7.8e-12 45.4 4.8 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF3328) Chlam_OMP3 PF03503.13 EPE32558.1 - 0.089 13.1 0.7 0.24 11.7 0.7 1.7 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 V-ATPase_H_N PF03224.14 EPE32559.1 - 9.6e-77 258.4 0.0 2e-76 257.3 0.0 1.5 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EPE32559.1 - 4.2e-36 123.6 0.1 1.2e-35 122.1 0.1 1.8 1 0 0 1 1 1 1 V-ATPase subunit H GCV_T PF01571.21 EPE32560.1 - 1.4e-84 283.5 0.0 1.8e-84 283.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EPE32560.1 - 1.5e-24 85.7 0.2 3.3e-24 84.6 0.2 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain MAP65_ASE1 PF03999.12 EPE32560.1 - 1.4 7.5 2.8 1.9 7.1 2.8 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Sulfate_transp PF00916.20 EPE32561.1 - 4e-64 216.7 16.3 5.9e-64 216.2 16.3 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 EPE32561.1 - 2.7e-16 59.4 0.0 4.6e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 EPE32561.1 - 2.5e-10 40.0 0.0 4.5e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF5389 PF17364.2 EPE32561.1 - 0.046 13.8 0.3 0.15 12.1 0.3 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5389) MFS_MOT1 PF16983.5 EPE32561.1 - 0.096 13.1 21.2 0.028 14.8 4.5 3.6 4 0 0 4 4 4 0 Molybdate transporter of MFS superfamily DUF2613 PF11021.8 EPE32561.1 - 0.86 9.8 3.4 2.9 8.1 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Sld5 PF05916.11 EPE32562.1 - 1.3e-12 48.1 0.0 2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein HMG_box PF00505.19 EPE32563.1 - 5.9e-11 42.6 0.3 5.9e-11 42.6 0.3 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EPE32563.1 - 0.0014 19.2 0.3 0.0039 17.7 0.3 1.8 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 EPE32563.1 - 0.026 13.8 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box PHD PF00628.29 EPE32564.1 - 4.3e-09 36.1 8.6 8.2e-09 35.2 8.6 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EPE32564.1 - 0.0016 18.0 4.8 0.0029 17.1 4.8 1.4 1 0 0 1 1 1 1 PHD-finger Ion_trans PF00520.31 EPE32565.1 - 1.1e-130 434.1 77.1 5.1e-42 143.8 4.9 4.7 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 EPE32565.1 - 0.013 15.3 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 EPE32565.1 - 0.033 13.7 0.0 0.13 11.8 0.0 2.1 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EPE32565.1 - 0.061 13.8 0.0 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 EPE32565.1 - 0.088 12.8 0.0 0.44 10.6 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain Helo_like_N PF17111.5 EPE32566.1 - 9.2e-05 21.9 0.2 0.00026 20.4 0.1 1.9 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins T2SSF PF00482.23 EPE32566.1 - 0.025 14.6 0.6 0.047 13.7 0.6 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF3835 PF12927.7 EPE32566.1 - 8.8 7.3 7.7 0.59 11.0 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) FPN1 PF06963.12 EPE32568.1 - 3.9e-69 233.3 10.7 1.6e-51 175.3 2.7 2.1 2 0 0 2 2 2 2 Ferroportin1 (FPN1) Oleosin PF01277.17 EPE32568.1 - 0.6 9.9 4.6 12 5.7 0.1 2.9 2 0 0 2 2 2 0 Oleosin Atg14 PF10186.9 EPE32568.1 - 0.8 8.7 1.9 2.5 7.1 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Copper-fist PF00649.18 EPE32569.1 - 7.8e-19 66.9 0.5 1.7e-18 65.8 0.5 1.6 1 0 0 1 1 1 1 Copper fist DNA binding domain Stb3 PF10330.9 EPE32570.1 - 0.095 12.7 0.1 0.11 12.5 0.1 1.1 1 0 0 1 1 1 0 Putative Sin3 binding protein Methyltransf_16 PF10294.9 EPE32571.1 - 3.3e-15 56.2 0.0 4.2e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 EPE32571.1 - 0.0033 16.8 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PrmA PF06325.13 EPE32571.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NNMT_PNMT_TEMT PF01234.17 EPE32571.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Cupin_8 PF13621.6 EPE32572.1 - 3e-28 99.2 0.1 9.5e-27 94.3 0.0 2.2 1 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 EPE32572.1 - 0.014 15.8 0.2 2.3 8.7 0.0 3.5 4 0 0 4 4 4 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 EPE32572.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 Cupin domain RNA_capsid PF03035.14 EPE32573.1 - 0.096 12.7 0.2 0.096 12.7 0.2 1.5 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein zf-C2H2_aberr PF17017.5 EPE32574.1 - 0.01 16.0 1.0 0.018 15.2 1.0 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger DUF5075 PF16825.5 EPE32574.1 - 0.038 13.7 0.2 0.15 11.7 0.1 2.1 2 0 0 2 2 2 0 IGP family C-type lectin domain zf-C2H2 PF00096.26 EPE32574.1 - 0.19 12.2 5.5 1.2 9.7 0.4 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE32574.1 - 0.3 12.0 5.4 16 6.6 0.8 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger Use1 PF09753.9 EPE32575.1 - 4.1e-09 36.5 6.0 5.9e-08 32.7 6.0 2.1 1 1 0 1 1 1 1 Membrane fusion protein Use1 Pox_A_type_inc PF04508.12 EPE32575.1 - 2.6 8.0 4.9 2.5 8.1 2.1 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Spc24 PF08286.11 EPE32575.1 - 4.9 7.5 7.8 0.28 11.5 1.2 2.2 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 BRCT PF00533.26 EPE32576.1 - 6.2e-06 26.5 0.1 2e-05 24.9 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EPE32576.1 - 3.1e-05 23.9 0.3 0.00016 21.6 0.2 2.2 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 EPE32576.1 - 4.1e-05 23.9 0.1 0.00018 21.8 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain MMR1 PF08505.10 EPE32576.1 - 0.016 15.6 0.7 0.029 14.7 0.7 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein BUD22 PF09073.10 EPE32576.1 - 0.061 12.7 10.5 0.098 12.0 10.5 1.3 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 EPE32576.1 - 0.87 8.1 14.3 1.6 7.2 14.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 EPE32576.1 - 1.7 6.8 7.8 2.6 6.2 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EPE32576.1 - 2.3 6.3 11.7 3.8 5.6 11.7 1.3 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 EPE32576.1 - 7.5 6.3 10.7 14 5.4 10.7 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein IGPS PF00218.21 EPE32577.1 - 2.5e-96 321.7 0.0 9.2e-96 319.9 0.0 1.9 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EPE32577.1 - 1.9e-49 168.1 0.5 1.1e-46 159.1 0.9 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 EPE32577.1 - 3.4e-44 150.9 0.0 6.6e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EPE32577.1 - 2.8e-05 24.0 0.2 8e-05 22.5 0.2 1.7 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 EPE32577.1 - 0.0028 17.4 2.5 0.35 10.6 0.2 3.8 3 1 1 4 4 4 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 EPE32577.1 - 0.0074 15.5 1.3 0.032 13.4 0.0 2.5 3 0 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 EPE32577.1 - 0.011 15.2 0.1 0.078 12.4 0.0 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein Nup188_C PF18378.1 EPE32578.1 - 4.2e-146 486.5 0.0 1.9e-145 484.4 0.0 2.0 2 0 0 2 2 2 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 EPE32578.1 - 5.7e-72 243.0 0.1 9.8e-60 202.5 0.0 3.2 3 1 0 3 3 3 2 Nucleoporin subcomplex protein binding to Pom34 DUF4758 PF15950.5 EPE32578.1 - 0.31 11.4 2.3 1.3 9.3 0.1 2.6 2 0 0 2 2 2 0 Putative sperm flagellar membrane protein DUF4726 PF15855.5 EPE32579.1 - 7.7 6.8 8.1 0.17 12.1 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) PAF-AH_p_II PF03403.13 EPE32580.1 - 4.6e-11 41.8 0.0 3.1e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 EPE32580.1 - 3e-05 23.4 0.0 0.13 11.5 0.0 2.5 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPE32580.1 - 0.0019 18.8 0.1 0.0035 18.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EPE32580.1 - 0.0025 17.6 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EPE32580.1 - 0.0029 16.6 0.0 0.0057 15.6 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 EPE32580.1 - 0.0078 15.9 0.1 0.071 12.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1754 PF08555.10 EPE32581.1 - 1.2e-13 51.6 6.2 2.1e-13 50.9 6.2 1.3 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) CDC27 PF09507.10 EPE32581.1 - 0.0064 15.9 3.4 0.0071 15.8 3.4 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Mucin PF01456.17 EPE32582.1 - 2.5e-08 34.0 0.7 2.5e-08 34.0 0.7 5.1 1 1 3 4 4 4 1 Mucin-like glycoprotein DUF5345 PF17280.2 EPE32582.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Melibiase_2 PF16499.5 EPE32583.1 - 3.1e-63 213.6 2.6 4.7e-63 213.0 2.6 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EPE32583.1 - 7.9e-09 35.5 2.6 2.8e-07 30.5 0.0 2.6 3 0 0 3 3 3 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EPE32583.1 - 5.8e-07 28.8 0.0 1.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Melibiase NmrA PF05368.13 EPE32584.1 - 2.3e-33 115.7 0.1 3e-33 115.3 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE32584.1 - 1.1e-17 64.5 0.1 1.4e-17 64.2 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EPE32584.1 - 0.0043 17.3 0.0 0.007 16.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EPE32584.1 - 0.0055 16.2 0.0 0.017 14.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EPE32584.1 - 0.11 13.0 0.0 0.26 11.7 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain zf-Tim10_DDP PF02953.15 EPE32585.1 - 1.1e-17 63.4 2.2 1.1e-17 63.4 2.2 1.5 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Mgr1 PF08602.10 EPE32585.1 - 0.0043 15.9 0.5 0.0044 15.9 0.5 1.1 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit RhoGAP PF00620.27 EPE32586.1 - 5.8e-38 130.1 0.0 9.4e-38 129.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain O-FucT PF10250.9 EPE32587.1 - 1.5e-16 61.1 0.0 2.8e-16 60.1 0.0 1.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Clr5 PF14420.6 EPE32588.1 - 8.2e-19 67.6 7.8 2.4e-18 66.1 7.8 1.8 1 0 0 1 1 1 1 Clr5 domain AAA PF00004.29 EPE32588.1 - 4.1e-18 66.1 0.0 9.6e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPE32588.1 - 0.00096 19.4 0.6 0.019 15.2 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 EPE32588.1 - 0.0089 16.4 0.4 0.04 14.3 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain Torsin PF06309.11 EPE32588.1 - 0.16 12.1 0.1 0.68 10.0 0.0 2.1 2 0 0 2 2 2 0 Torsin AAA_11 PF13086.6 EPE32588.1 - 0.47 10.2 2.8 0.93 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain HET PF06985.11 EPE32591.1 - 2.6e-23 83.0 0.1 4.8e-23 82.1 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lipase_GDSL PF00657.22 EPE32593.1 - 3.6e-05 23.8 0.0 4.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EPE32593.1 - 0.00035 21.0 0.0 0.00061 20.2 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family tRNA-synt_2b PF00587.25 EPE32594.1 - 2.1e-22 80.0 0.0 3.5e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EPE32594.1 - 2.3e-09 37.4 8.6 1.8e-08 34.6 8.6 2.2 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Suf PF05843.14 EPE32594.1 - 0.14 12.2 4.3 0.22 11.5 4.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Actin PF00022.19 EPE32595.1 - 1.1e-18 67.1 0.0 1.9e-07 30.0 0.0 3.0 3 0 0 3 3 3 3 Actin GEN1_C PF18380.1 EPE32596.1 - 5.6e-28 97.9 0.0 2.5e-27 95.8 0.0 2.2 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 EPE32596.1 - 5e-24 84.5 0.0 1e-23 83.5 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EPE32596.1 - 2.6e-07 31.0 0.0 5.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain BTB PF00651.31 EPE32597.1 - 0.17 12.1 0.0 0.44 10.8 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain TT1725 PF18324.1 EPE32597.1 - 0.18 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Hypothetical protein TT1725 CH PF00307.31 EPE32600.1 - 1.8e-15 57.1 0.0 3.3e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EPE32600.1 - 0.0013 18.5 0.1 0.003 17.3 0.1 1.5 1 0 0 1 1 1 1 CAMSAP CH domain Pox_A_type_inc PF04508.12 EPE32600.1 - 0.0072 16.1 0.6 0.0072 16.1 0.6 3.6 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat PI-PLC-X PF00388.19 EPE32601.1 - 1.9e-60 202.7 0.1 3.5e-60 201.8 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EPE32601.1 - 9.9e-43 145.1 0.1 2.8e-42 143.7 0.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EPE32601.1 - 1.1e-05 25.6 0.0 0.00014 22.1 0.0 2.3 1 1 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 EPE32601.1 - 0.0019 18.7 0.2 0.0039 17.6 0.2 1.5 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.6 EPE32601.1 - 0.0022 18.4 0.6 0.027 14.9 0.5 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EPE32601.1 - 0.0041 16.6 0.1 0.0041 16.6 0.1 2.3 3 0 0 3 3 3 1 EF hand EF-hand_1 PF00036.32 EPE32601.1 - 0.016 14.7 0.1 0.016 14.7 0.1 3.2 4 0 0 4 4 4 0 EF hand GDPD PF03009.17 EPE32601.1 - 0.024 14.4 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family PH_12 PF16457.5 EPE32601.1 - 0.025 15.1 0.2 0.098 13.2 0.2 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain EF-hand_6 PF13405.6 EPE32601.1 - 1.2 9.3 11.4 0.12 12.4 0.2 3.5 4 0 0 4 4 4 0 EF-hand domain HATPase_c PF02518.26 EPE32603.1 - 3.7e-30 104.7 0.0 1.4e-29 102.8 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPE32603.1 - 6.9e-21 74.5 0.0 1.8e-20 73.2 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPE32603.1 - 7.1e-19 67.6 1.3 1.6e-18 66.5 0.4 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 EPE32603.1 - 2e-13 51.1 0.0 7.9e-13 49.1 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain GAF_2 PF13185.6 EPE32603.1 - 3.8e-13 49.9 0.0 1.3e-12 48.2 0.0 2.0 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 EPE32603.1 - 2.1e-08 33.9 0.0 4.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 EPE32603.1 - 2.2e-07 31.6 0.0 6.9e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.17 EPE32603.1 - 0.00072 18.9 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c_3 PF13589.6 EPE32603.1 - 0.0042 16.9 0.1 0.0094 15.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 EPE32603.1 - 0.0079 16.5 0.0 0.046 14.1 0.0 2.3 2 0 0 2 2 2 1 GAF domain TPR_19 PF14559.6 EPE32603.1 - 0.015 15.8 2.3 0.6 10.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MeaB PF03308.16 EPE32603.1 - 0.025 13.6 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 EPE32603.1 - 0.096 12.6 0.0 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 EPE32603.1 - 0.13 11.4 0.0 0.56 9.4 0.0 2.0 1 1 0 1 1 1 0 NB-ARC domain TPR_12 PF13424.6 EPE32603.1 - 0.57 10.5 8.6 3.9 7.8 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat NAD_binding_8 PF13450.6 EPE32604.1 - 4.1e-08 33.3 0.0 1.1e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE32604.1 - 0.00023 20.5 0.0 0.02 14.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EPE32604.1 - 0.00025 20.5 0.0 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EPE32604.1 - 0.0035 16.7 0.0 0.0066 15.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE32604.1 - 0.0038 16.5 0.1 0.01 15.1 0.1 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EPE32604.1 - 0.017 14.4 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EPE32604.1 - 0.049 12.3 0.1 0.084 11.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 EPE32604.1 - 0.066 13.2 0.2 0.66 10.0 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding INO80_Ies4 PF08193.11 EPE32605.1 - 5.7e-83 278.6 20.7 5.7e-83 278.6 20.7 1.7 2 0 0 2 2 2 1 INO80 complex subunit Ies4 CLTH PF10607.9 EPE32606.1 - 2.1e-30 105.6 0.2 2.9e-30 105.1 0.2 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EPE32606.1 - 4.3e-24 84.9 0.0 9.3e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 EPE32606.1 - 5.1e-05 23.1 0.6 0.00054 19.8 0.0 2.8 3 0 0 3 3 3 1 LisH SMC_ScpB PF04079.16 EPE32606.1 - 0.089 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB CHRD PF07452.12 EPE32607.1 - 6.3e-13 49.7 0.1 9.2e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 CHRD domain GST_C_6 PF17171.4 EPE32608.1 - 6.8e-20 70.6 0.0 1.3e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EPE32608.1 - 2e-19 70.2 0.0 4.3e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 EPE32608.1 - 2.1e-11 44.2 0.1 3.6e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 EPE32608.1 - 5.5e-05 23.1 0.1 9.4e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SAM35 PF10806.8 EPE32608.1 - 0.014 15.6 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 SAM35, subunit of SAM coomplex CMV_US PF08001.11 EPE32610.1 - 0.19 11.0 3.7 0.22 10.8 3.7 1.1 1 0 0 1 1 1 0 CMV US FTZ PF03867.14 EPE32610.1 - 0.3 10.6 12.8 0.33 10.5 12.8 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region CCDC106 PF15794.5 EPE32610.1 - 0.56 9.9 8.7 0.59 9.8 8.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Pex14_N PF04695.13 EPE32610.1 - 0.73 10.5 14.1 0.87 10.2 14.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Band_3_cyto PF07565.13 EPE32610.1 - 1.4 8.7 8.5 1.5 8.5 8.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain NPR3 PF03666.13 EPE32610.1 - 1.4 7.6 9.9 1.8 7.3 9.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 EPE32610.1 - 1.8 7.3 9.9 1.9 7.2 9.9 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 EPE32610.1 - 2.3 6.2 10.5 2.5 6.1 10.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.13 EPE32610.1 - 4 7.3 18.0 4.4 7.2 18.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDP_N PF12278.8 EPE32610.1 - 7.7 6.6 11.0 20 5.3 11.0 1.7 1 1 0 1 1 1 0 Sex determination protein N terminal APH PF01636.23 EPE32611.1 - 3.1e-10 40.4 0.1 7.9e-10 39.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE32611.1 - 4.1e-06 26.5 0.0 5.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EPE32611.1 - 0.0007 19.0 0.0 0.0009 18.6 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EPE32611.1 - 0.07 12.0 0.0 0.09 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RIO1 PF01163.22 EPE32611.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family UPF0167 PF03691.14 EPE32611.1 - 0.17 11.7 0.9 0.32 10.8 0.9 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0167) APG6_N PF17675.1 EPE32612.1 - 7.8 7.0 8.1 0.72 10.4 2.3 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region PSP1 PF04468.12 EPE32613.1 - 7.7e-27 93.4 1.9 1.2e-26 92.8 1.9 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.11 EPE32614.1 - 5e-28 97.0 0.0 1.5e-27 95.5 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EPE32614.1 - 3e-26 91.4 0.2 5.4e-26 90.5 0.2 1.4 1 0 0 1 1 1 1 NifU-like domain DUF333 PF03891.15 EPE32614.1 - 0.071 13.3 0.1 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF333) Amidohydro_2 PF04909.14 EPE32614.1 - 0.14 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase zf-HIT PF04438.16 EPE32615.1 - 7e-09 35.4 12.4 9.6e-09 35.0 12.4 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EPE32615.1 - 0.0062 16.6 9.1 0.01 15.9 9.1 1.4 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.24 EPE32615.1 - 0.41 10.8 7.9 0.68 10.1 7.9 1.4 1 0 0 1 1 1 0 B-box zinc finger RasGEF PF00617.19 EPE32617.1 - 1.3e-44 152.5 0.1 2.4e-44 151.6 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EPE32617.1 - 2.7e-12 46.9 0.0 1.1e-11 44.9 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.22 EPE32617.1 - 8.5e-07 28.7 0.0 2.7e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Ras family ABC_tran PF00005.27 EPE32617.1 - 0.035 14.6 0.0 0.098 13.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 EPE32617.1 - 0.035 13.8 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.23 EPE32617.1 - 0.076 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 EPE32617.1 - 0.11 11.6 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Roc PF08477.13 EPE32617.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ribosomal_L15e PF00827.17 EPE32618.1 - 4.4e-89 297.3 9.8 5.5e-89 297.0 9.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 HECT PF00632.25 EPE32619.1 - 6.3e-73 245.9 0.0 8.6e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) L51_S25_CI-B8 PF05047.16 EPE32620.1 - 5.7e-10 39.0 0.0 9e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MMR_HSR1 PF01926.23 EPE32621.1 - 0.0001 22.4 0.0 0.32 11.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase ATPase-cat_bd PF12156.8 EPE32621.1 - 0.21 12.4 0.0 0.45 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Ank_2 PF12796.7 EPE32623.1 - 0.14 12.8 0.0 0.35 11.5 0.0 1.9 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) EssA PF10661.9 EPE32623.1 - 0.27 11.1 5.7 0.048 13.5 1.1 1.9 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA DUF4674 PF15719.5 EPE32623.1 - 7 6.6 9.8 1.7 8.6 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4674) zf-FPG_IleRS PF06827.14 EPE32624.1 - 0.012 15.5 0.1 0.021 14.7 0.1 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-CSL PF05207.13 EPE32625.1 - 2.8e-17 62.2 0.3 4.4e-17 61.5 0.3 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EPE32625.1 - 4.5e-11 42.7 0.1 6.9e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain HMGL-like PF00682.19 EPE32626.1 - 4.1e-78 262.6 0.6 4.1e-78 262.6 0.6 1.8 2 0 0 2 2 2 1 HMGL-like Methyltransf_23 PF13489.6 EPE32627.1 - 9.6e-20 71.1 0.0 1.6e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE32627.1 - 6.4e-09 36.4 0.0 1.5e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE32627.1 - 1.5e-08 34.6 0.0 1.5e-07 31.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE32627.1 - 2.7e-05 24.8 0.0 0.00019 22.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE32627.1 - 0.00015 22.3 0.0 0.00035 21.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EPE32627.1 - 0.0049 16.3 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EPE32627.1 - 0.0069 16.5 0.0 0.0096 16.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EPE32627.1 - 0.01 15.6 0.0 0.065 13.0 0.0 2.0 2 0 0 2 2 2 0 Lysine methyltransferase Ubie_methyltran PF01209.18 EPE32627.1 - 0.012 14.9 0.0 0.12 11.7 0.0 2.4 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 EPE32627.1 - 0.029 14.1 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.14 EPE32627.1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain HTH_24 PF13412.6 EPE32627.1 - 0.086 12.4 0.0 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding PCMT PF01135.19 EPE32627.1 - 0.15 11.8 0.0 0.51 10.0 0.0 1.9 2 1 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EPE32627.1 - 0.19 11.2 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase GidB PF02527.15 EPE32627.1 - 0.21 10.9 0.0 0.61 9.4 0.0 1.6 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G HPP PF04982.13 EPE32628.1 - 1.5e-40 138.2 3.0 1.5e-40 138.2 3.0 1.4 2 0 0 2 2 2 1 HPP family HlyIII PF03006.20 EPE32629.1 - 3.3e-62 210.1 15.7 4.3e-62 209.8 15.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.13 EPE32629.1 - 0.19 11.9 1.8 0.78 9.9 1.1 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) p450 PF00067.22 EPE32630.1 - 1.5e-74 251.5 0.0 1.7e-74 251.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAGAT PF03982.13 EPE32631.1 - 1.5e-94 316.3 0.0 2e-94 315.8 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 EPE32631.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Rer1 family zf-H2C2_2 PF13465.6 EPE32632.1 - 1.9e-13 50.2 20.7 1.3e-07 31.7 2.0 3.9 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 EPE32632.1 - 2.5e-11 43.4 27.0 0.00035 20.9 6.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE32632.1 - 4.7e-09 36.3 22.5 0.0054 17.5 4.6 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE32632.1 - 0.0023 18.2 12.0 0.6 10.5 0.7 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 EPE32632.1 - 0.0025 18.1 3.3 1.3 9.3 0.1 3.4 3 0 0 3 3 3 1 zinc-ribbon zf-C2H2_9 PF16293.5 EPE32632.1 - 0.0066 16.3 4.8 6.8 6.6 0.2 3.5 2 1 1 3 3 3 1 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 EPE32632.1 - 0.013 15.8 12.7 0.034 14.4 8.4 2.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CHCC PF10276.9 EPE32632.1 - 0.021 14.9 5.2 0.55 10.3 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_6 PF13912.6 EPE32632.1 - 0.023 14.7 24.0 0.11 12.5 0.1 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger YabA PF06156.13 EPE32632.1 - 0.03 14.9 5.9 0.073 13.7 5.9 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Rad50_zn_hook PF04423.14 EPE32632.1 - 0.083 12.7 7.8 0.12 12.2 0.6 3.1 3 0 0 3 3 2 0 Rad50 zinc hook motif Zn-ribbon_8 PF09723.10 EPE32632.1 - 0.11 12.7 5.2 0.26 11.4 1.6 2.5 2 0 0 2 2 2 0 Zinc ribbon domain DUF16 PF01519.16 EPE32632.1 - 0.31 11.5 3.6 0.59 10.6 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Rpr2 PF04032.16 EPE32632.1 - 0.41 11.0 4.3 4.1 7.8 1.3 2.6 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain GAS PF13851.6 EPE32632.1 - 0.44 9.9 7.6 0.83 9.0 7.6 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CCDC106 PF15794.5 EPE32632.1 - 0.63 9.7 6.9 0.051 13.3 1.4 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DZR PF12773.7 EPE32632.1 - 0.73 9.9 6.7 7.2 6.7 6.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon NuA4 PF09340.10 EPE32632.1 - 1.1 9.2 4.7 32 4.5 0.5 3.4 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 XhlA PF10779.9 EPE32632.1 - 1.9 8.8 3.9 3.7 7.8 3.9 1.4 1 0 0 1 1 1 0 Haemolysin XhlA zf-C2H2_2 PF12756.7 EPE32632.1 - 3.4 8.0 14.3 5.2 7.5 1.5 3.4 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) COPIIcoated_ERV PF07970.12 EPE32633.1 - 0.09 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum vesicle transporter Kinesin PF00225.23 EPE32634.1 - 5.2e-94 314.9 0.0 9.9e-94 314.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EPE32634.1 - 2.1e-22 79.6 0.0 2.4e-21 76.3 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 EPE32634.1 - 0.016 15.0 3.3 0.2 11.5 0.7 2.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 EPE32634.1 - 0.42 9.9 10.4 0.29 10.4 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Stk19 PF10494.9 EPE32635.1 - 9.4e-86 287.5 0.0 1.1e-85 287.2 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 His_Phos_1 PF00300.22 EPE32636.1 - 0.014 15.1 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Homeodomain PF00046.29 EPE32638.1 - 5.1e-13 48.7 6.1 1.5e-12 47.2 6.1 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EPE32638.1 - 0.045 13.7 0.4 0.14 12.1 0.4 1.8 1 0 0 1 1 1 0 Homeobox KN domain Ras PF00071.22 EPE32639.1 - 2.8e-48 163.6 0.0 5.1e-48 162.7 0.0 1.4 1 0 0 1 1 1 1 Ras family Nas2_N PF18265.1 EPE32639.1 - 1.1e-29 102.1 0.1 1.9e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain Roc PF08477.13 EPE32639.1 - 2.8e-28 98.6 0.0 1e-27 96.7 0.0 2.0 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE32639.1 - 5.5e-10 39.0 0.0 8.7e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PDZ_6 PF17820.1 EPE32639.1 - 6e-06 26.0 0.0 2.1e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EPE32639.1 - 0.00027 21.2 0.2 0.00095 19.4 0.0 2.0 2 0 0 2 2 2 1 PDZ domain RNA_helicase PF00910.22 EPE32639.1 - 0.00073 19.9 0.0 0.0073 16.7 0.0 2.6 2 1 0 2 2 2 1 RNA helicase PDZ PF00595.24 EPE32639.1 - 0.0022 18.3 0.0 0.0062 16.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain MMR_HSR1 PF01926.23 EPE32639.1 - 0.0038 17.3 0.1 0.0099 16.0 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EPE32639.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 EPE32639.1 - 0.029 13.9 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 EPE32639.1 - 0.055 12.9 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 EPE32639.1 - 0.11 11.6 1.6 3.4 6.7 0.1 2.5 2 1 0 2 2 2 0 G-protein alpha subunit ArgoMid PF16487.5 EPE32639.1 - 0.13 12.6 0.2 0.39 11.0 0.0 1.9 2 0 0 2 2 2 0 Mid domain of argonaute TsaE PF02367.17 EPE32639.1 - 0.17 11.9 0.1 0.38 10.8 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RhoGEF PF00621.20 EPE32640.1 - 2.9e-22 79.8 0.0 5.2e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain CorA PF01544.18 EPE32642.1 - 0.00025 20.5 0.3 0.00053 19.4 0.3 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PolyA_pol PF01743.20 EPE32642.1 - 0.11 12.9 0.1 0.23 11.9 0.1 1.5 1 0 0 1 1 1 0 Poly A polymerase head domain Sa_NUDIX PF18167.1 EPE32643.1 - 0.13 12.1 0.5 0.14 12.0 0.5 1.0 1 0 0 1 1 1 0 SMODS-associated NUDIX domain DUF3638 PF12340.8 EPE32644.1 - 1e-94 316.1 3.0 1.8e-94 315.3 3.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EPE32644.1 - 1.2e-15 56.5 0.1 3.4e-15 55.1 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Pkinase PF00069.25 EPE32644.1 - 4.5e-12 45.9 0.0 9.9e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain p450 PF00067.22 EPE32645.1 - 1.2e-46 159.4 0.1 1.6e-46 159.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2401 PF10287.9 EPE32646.1 - 6.8e-86 287.6 0.0 9.5e-86 287.1 0.0 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EPE32646.1 - 4.1e-25 88.0 0.0 9.8e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Topo_Zn_Ribbon PF08272.11 EPE32646.1 - 0.19 11.4 0.1 0.41 10.3 0.1 1.5 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like FctA PF12892.7 EPE32647.1 - 0.054 14.3 0.1 0.13 13.0 0.0 1.7 1 1 0 1 1 1 0 Spy0128-like isopeptide containing domain Atg14 PF10186.9 EPE32648.1 - 6e-78 262.1 0.0 8.2e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 AIP3 PF03915.13 EPE32648.1 - 0.029 13.5 2.3 0.046 12.8 2.3 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 Spc7 PF08317.11 EPE32648.1 - 0.11 11.4 2.6 0.17 10.7 2.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 EPE32648.1 - 0.21 10.8 1.0 0.31 10.2 1.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein FAM76 PF16046.5 EPE32648.1 - 0.34 10.2 8.0 0.027 13.8 2.5 1.7 2 0 0 2 2 2 0 FAM76 protein DUF1041 PF06292.17 EPE32649.1 - 0.066 13.6 1.3 0.11 12.9 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) DUF3807 PF12720.7 EPE32650.1 - 1.7e-53 181.6 4.0 2e-53 181.4 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) CDC45 PF02724.14 EPE32650.1 - 0.21 9.9 3.8 0.23 9.7 3.8 1.0 1 0 0 1 1 1 0 CDC45-like protein TMEM191C PF15194.6 EPE32651.1 - 0.091 12.9 0.2 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 TMEM191C family DUF4448 PF14610.6 EPE32652.1 - 3.7e-50 170.3 0.0 4.9e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SBP56 PF05694.11 EPE32652.1 - 0.034 13.0 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) TipAS PF07739.13 EPE32653.1 - 0.086 13.4 0.1 0.28 11.7 0.0 1.8 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Adaptin_binding PF10199.9 EPE32654.1 - 0.064 13.9 0.3 0.089 13.4 0.3 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 SKG6 PF08693.10 EPE32657.1 - 4.5e-05 22.8 0.2 9.6e-05 21.7 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RicinB_lectin_2 PF14200.6 EPE32657.1 - 0.0013 19.4 0.4 0.89 10.3 0.0 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like VSP PF03302.13 EPE32657.1 - 0.03 13.2 0.2 0.04 12.8 0.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Gram_pos_anchor PF00746.21 EPE32657.1 - 0.033 14.1 3.0 0.075 13.0 3.0 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DIPSY PF11763.8 EPE32657.1 - 0.07 13.3 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal MGC-24 PF05283.11 EPE32657.1 - 0.076 13.5 1.5 0.13 12.7 1.5 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Spt46 PF17734.1 EPE32657.1 - 2.3 7.9 6.4 3.6 7.3 6.4 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 DUF829 PF05705.14 EPE32659.1 - 8.6e-42 143.7 0.0 1e-41 143.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) GATA PF00320.27 EPE32661.1 - 2.4e-13 49.4 4.2 5.4e-13 48.3 4.2 1.7 1 0 0 1 1 1 1 GATA zinc finger Sid-5 PF17204.3 EPE32662.1 - 0.17 12.1 0.1 0.37 11.0 0.1 1.5 1 0 0 1 1 1 0 Sid-5 family DUF1295 PF06966.12 EPE32663.1 - 8.4e-54 182.6 0.2 1.1e-53 182.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) GFA PF04828.14 EPE32663.1 - 4e-06 27.1 0.1 8.2e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Steroid_dh PF02544.16 EPE32663.1 - 1.5e-05 25.0 1.7 9.3e-05 22.5 0.1 2.7 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 EPE32663.1 - 3.9e-05 24.0 0.0 8.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EPE32663.1 - 8.1e-05 23.0 0.0 0.00085 19.7 0.1 2.4 1 1 1 2 2 2 1 Phospholipid methyltransferase RINGv PF12906.7 EPE32664.1 - 2.1e-16 59.8 9.2 2.1e-16 59.8 9.2 1.8 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 EPE32664.1 - 0.0086 16.4 8.9 0.016 15.5 8.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 EPE32664.1 - 0.26 11.3 3.3 0.63 10.1 3.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EPE32664.1 - 2.8 7.8 6.1 5.9 6.8 6.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain KRE9 PF05390.11 EPE32665.1 - 3.7e-15 56.5 6.6 3.7e-15 56.5 6.6 1.9 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 EPE32665.1 - 4.5e-09 37.0 0.2 1e-08 35.8 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PALP PF00291.25 EPE32666.1 - 1.1e-63 215.4 0.1 1.6e-63 214.9 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EPE32666.1 - 1.1e-11 45.0 0.0 1.6e-08 34.9 0.0 3.1 3 0 0 3 3 3 2 CBS domain SRPRB PF09439.10 EPE32667.1 - 1.4e-33 115.9 0.0 1.1e-32 112.9 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EPE32667.1 - 9.4e-06 25.9 0.1 3.9e-05 23.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain Arf PF00025.21 EPE32667.1 - 1.7e-05 24.4 0.0 0.0011 18.5 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPE32667.1 - 4.3e-05 23.6 0.0 9.3e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EPE32667.1 - 8.2e-05 23.1 0.3 0.00014 22.3 0.3 1.5 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 EPE32667.1 - 0.00013 21.4 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EPE32667.1 - 0.00026 20.6 0.0 0.001 18.7 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EPE32667.1 - 0.0004 20.2 0.0 0.059 13.1 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein TniB PF05621.11 EPE32667.1 - 0.0025 17.3 0.0 0.014 14.8 0.0 1.9 1 1 1 2 2 2 1 Bacterial TniB protein Roc PF08477.13 EPE32667.1 - 0.0055 16.9 0.0 0.019 15.2 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EPE32667.1 - 0.0073 16.2 0.8 0.13 12.1 0.4 2.6 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EPE32667.1 - 0.0082 16.7 0.2 0.016 15.7 0.1 1.7 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EPE32667.1 - 0.0095 15.8 0.1 0.021 14.7 0.1 1.6 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EPE32667.1 - 0.018 14.7 0.3 0.047 13.4 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 EPE32667.1 - 0.022 14.4 0.1 1.7 8.2 0.1 2.4 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 EPE32667.1 - 0.023 13.9 0.0 1.5 7.9 0.2 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA PF00004.29 EPE32667.1 - 0.023 15.1 0.4 0.19 12.1 0.4 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 EPE32667.1 - 0.023 14.0 0.0 0.054 12.8 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 EPE32667.1 - 0.026 14.3 0.1 0.072 12.8 0.1 1.8 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 EPE32667.1 - 0.037 14.0 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EPE32667.1 - 0.071 13.7 0.0 0.1 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 EPE32667.1 - 0.081 12.5 0.0 0.77 9.3 0.0 2.2 2 1 0 2 2 2 0 Ras family SRP54 PF00448.22 EPE32667.1 - 0.1 12.2 0.1 11 5.6 0.1 2.3 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain RuvB_N PF05496.12 EPE32667.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 EPE32667.1 - 0.15 11.8 0.0 0.72 9.6 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 EPE32667.1 - 0.3 11.3 0.6 1.5 9.0 0.3 2.0 1 1 1 2 2 2 0 AAA domain Ank_2 PF12796.7 EPE32668.1 - 7e-39 132.3 1.6 1.7e-12 47.7 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE32668.1 - 2.5e-23 81.8 1.4 1.6e-06 28.3 0.0 4.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE32668.1 - 5.3e-22 75.5 2.8 3.6e-07 30.0 0.0 6.0 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EPE32668.1 - 8.5e-22 76.6 1.1 2.9e-05 24.3 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EPE32668.1 - 1.7e-20 73.1 2.7 1.3e-05 25.6 0.3 4.3 2 1 3 5 5 5 5 Ankyrin repeats (many copies) DHHC PF01529.20 EPE32668.1 - 0.00053 20.1 1.5 0.00053 20.1 1.5 3.6 2 2 1 3 3 3 1 DHHC palmitoyltransferase ATP-synt_C PF00137.21 EPE32669.1 - 5.6e-10 39.4 15.2 1e-09 38.6 15.2 1.5 1 0 0 1 1 1 1 ATP synthase subunit C Phage_holin_3_6 PF07332.11 EPE32669.1 - 0.036 14.1 2.5 0.064 13.3 2.5 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III EHN PF06441.12 EPE32670.1 - 5.7e-25 87.8 1.0 2.2e-23 82.7 0.0 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EPE32670.1 - 2.2e-07 30.8 0.0 3.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE32670.1 - 1.2 9.7 8.4 0.25 11.9 3.8 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_M14 PF00246.24 EPE32671.1 - 5.3e-77 259.5 0.0 6.7e-77 259.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.20 EPE32672.1 - 1.2e-29 103.3 0.0 2.2e-29 102.4 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 EPE32672.1 - 1.1e-06 29.1 0.3 3.1e-06 27.7 0.3 1.8 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 EPE32672.1 - 6e-06 26.6 0.1 1.5e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Zn_clus PF00172.18 EPE32673.1 - 2.3e-07 30.8 8.3 2.3e-07 30.8 8.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE32673.1 - 0.00019 20.4 0.7 0.00025 20.0 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 EPE32674.1 - 5.9e-11 42.4 0.0 8.1e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE32674.1 - 2.3e-09 37.0 0.1 1.9e-08 34.0 0.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EPE32674.1 - 0.0019 17.7 0.1 0.0068 15.9 0.0 1.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EPE32674.1 - 0.011 14.8 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.20 EPE32674.1 - 0.014 15.5 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EPE32674.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PsbI PF02532.14 EPE32677.1 - 0.095 12.7 0.2 0.095 12.7 0.2 1.7 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Endonuclease_NS PF01223.23 EPE32678.1 - 3.6e-68 229.8 0.0 4.5e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease WD40 PF00400.32 EPE32679.1 - 1.1e-27 95.7 20.6 0.00012 22.8 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE32679.1 - 3.1e-10 40.2 0.1 4 7.8 0.0 6.0 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE32679.1 - 0.12 12.3 0.1 5.4 6.8 0.0 2.8 1 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A MBOAT PF03062.19 EPE32680.1 - 3.2e-22 79.4 13.1 3.2e-22 79.4 13.1 2.0 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EPE32680.1 - 0.0072 16.6 1.5 0.023 15.0 1.5 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family RNase_PH PF01138.21 EPE32681.1 - 1.6e-22 80.4 0.0 2.7e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EPE32681.1 - 6.1e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1045 PF06299.12 EPE32681.1 - 0.06 13.3 0.0 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1045) Cwf_Cwc_15 PF04889.12 EPE32682.1 - 1.8e-87 293.1 19.1 2.1e-87 292.9 19.1 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 EPE32682.1 - 0.14 10.9 9.1 0.17 10.6 9.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Roughex PF06020.11 EPE32682.1 - 0.49 9.5 11.7 0.62 9.1 11.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Hid1 PF12722.7 EPE32682.1 - 1.4 7.0 3.7 1.4 7.0 3.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 EPE32682.1 - 2.8 6.1 19.2 3.2 5.9 19.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 EPE32682.1 - 4.1 6.7 9.0 5.5 6.3 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GTP-bdg_M PF16360.5 EPE32682.1 - 8.2 7.1 14.5 6.3 7.5 5.0 2.5 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region Tmemb_170 PF10190.9 EPE32685.1 - 5.6e-24 84.6 15.1 6.4e-24 84.4 15.1 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 AC_N PF16214.5 EPE32685.1 - 7.3 5.6 7.2 9.1 5.3 7.2 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Hexapep_2 PF14602.6 EPE32686.1 - 1.4e-13 50.3 5.8 1.1e-10 41.1 3.8 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 EPE32686.1 - 6.7e-12 45.5 0.2 1.1e-11 44.8 0.2 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 EPE32686.1 - 5.6e-11 41.7 8.3 1.4e-10 40.4 3.2 2.9 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) ICMT PF04140.14 EPE32687.1 - 3.7e-25 88.1 0.1 6.4e-25 87.4 0.1 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EPE32687.1 - 3.7e-11 43.3 0.8 7.4e-11 42.4 0.8 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 EPE32687.1 - 0.0022 17.5 0.1 0.0031 17.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 EPE32687.1 - 0.028 13.9 3.1 0.049 13.1 1.6 2.0 1 1 1 2 2 2 0 NnrU protein Zip PF02535.22 EPE32688.1 - 2.1e-18 66.6 14.3 1.4e-17 64.0 14.3 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Phage_holin_3_5 PF16085.5 EPE32688.1 - 0.14 12.3 1.8 0.27 11.4 0.4 2.2 2 0 0 2 2 2 0 Bacteriophage holin Hol, superfamily III Phage_holin_2_3 PF16080.5 EPE32688.1 - 0.17 11.6 1.7 0.24 11.2 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage holin family HP1 DUF1418 PF07214.12 EPE32688.1 - 0.97 9.3 3.4 3.8 7.4 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1418) TFIIE_beta PF02186.15 EPE32689.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 TFIIE beta subunit core domain DUF2507 PF10702.9 EPE32691.1 - 0.09 12.7 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2507) Lipase_GDSL_2 PF13472.6 EPE32692.1 - 2.2e-19 70.5 0.0 4e-19 69.7 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE32692.1 - 6.1e-16 59.0 0.0 7.8e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALF PF03752.13 EPE32692.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Short repeats of unknown function EIIA-man PF03610.16 EPE32692.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 PTS system fructose IIA component Voltage_CLC PF00654.20 EPE32693.1 - 2.1e-91 306.8 21.4 2.1e-91 306.8 21.4 1.9 2 1 0 2 2 2 1 Voltage gated chloride channel DUF4235 PF14019.6 EPE32693.1 - 0.12 12.4 4.0 0.55 10.4 1.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) Granulin PF00396.18 EPE32693.1 - 0.29 11.5 1.8 0.99 9.8 1.8 1.9 1 0 0 1 1 1 0 Granulin Lectin_leg-like PF03388.13 EPE32694.1 - 1.7e-64 217.4 0.0 2.6e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 EPE32694.1 - 5.7e-05 22.8 0.0 0.096 12.2 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain zf-Tim10_DDP PF02953.15 EPE32695.1 - 1e-23 82.7 1.4 1.2e-23 82.5 1.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3361 PF11841.8 EPE32695.1 - 0.074 13.0 0.0 0.19 11.7 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3361) DUF4372 PF14294.6 EPE32695.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4372) TerB_C PF15615.6 EPE32695.1 - 0.21 11.9 0.0 0.35 11.2 0.0 1.4 1 0 0 1 1 1 0 TerB-C domain DUF2040 PF09745.9 EPE32696.1 - 2e-37 127.9 22.2 2e-37 127.9 22.2 3.3 3 1 0 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) Pkinase PF00069.25 EPE32698.1 - 5.7e-72 242.2 0.0 7.9e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE32698.1 - 1.6e-38 132.5 0.0 2.6e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE32698.1 - 3.1e-08 33.3 0.3 5.9e-08 32.4 0.0 1.7 2 1 0 2 2 2 1 Kinase-like Rad21_Rec8 PF04824.16 EPE32698.1 - 0.0099 15.1 0.3 0.027 13.7 0.3 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein APH PF01636.23 EPE32698.1 - 0.018 15.0 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EPE32698.1 - 0.046 13.3 0.1 1.7 8.2 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EPE32698.1 - 0.06 12.3 0.1 0.098 11.6 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Ndc1_Nup PF09531.10 EPE32698.1 - 0.74 8.4 6.5 0.96 8.1 6.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 EPE32698.1 - 1.8 8.5 12.2 2.5 8.0 12.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HAUS-augmin3 PF14932.6 EPE32699.1 - 0.016 14.8 25.7 0.0068 16.0 21.8 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF3293 PF11697.8 EPE32699.1 - 0.066 13.7 5.6 4.5 7.8 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3293) PLAC9 PF15205.6 EPE32699.1 - 0.078 13.4 1.2 13 6.2 0.1 3.1 3 1 0 3 3 3 0 Placenta-specific protein 9 V_ATPase_I PF01496.19 EPE32699.1 - 0.92 7.3 12.0 1.4 6.7 12.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5344 PF17279.2 EPE32699.1 - 6.6 7.4 20.4 2.1 9.0 3.1 4.4 3 1 2 5 5 5 0 Family of unknown function (DUF5344) LrgB PF04172.16 EPE32700.1 - 1.5e-59 201.1 5.8 1.5e-59 201.1 5.8 2.2 3 0 0 3 3 3 1 LrgB-like family LrgA PF03788.14 EPE32700.1 - 0.00086 19.2 8.0 0.0044 16.9 8.0 2.3 1 0 0 1 1 1 1 LrgA family Rotamase PF00639.21 EPE32701.1 - 1.3e-20 74.1 0.0 2e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EPE32701.1 - 6.4e-15 55.7 0.0 9.7e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EPE32701.1 - 9.7e-07 28.8 0.6 9.7e-07 28.8 0.6 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 EPE32701.1 - 0.00016 22.5 0.0 0.00022 22.0 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW_1 PF18507.1 EPE32701.1 - 0.044 13.5 0.1 0.082 12.6 0.1 1.5 1 0 0 1 1 1 0 WW domain ADH_N PF08240.12 EPE32702.1 - 2.7e-08 33.7 0.0 6.1e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE32702.1 - 6.2e-06 26.2 0.1 1.4e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Nup96 PF12110.8 EPE32702.1 - 0.23 10.5 0.0 0.36 9.9 0.0 1.2 1 0 0 1 1 1 0 Nuclear protein 96 RNA_POL_M_15KD PF02150.16 EPE32703.1 - 6.3e-12 45.2 2.1 6.3e-12 45.2 2.1 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit GFA PF04828.14 EPE32703.1 - 0.0016 18.8 2.6 0.31 11.4 0.1 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme zf-C2HC5 PF06221.13 EPE32703.1 - 0.62 10.1 9.8 0.52 10.3 0.7 2.7 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type DZR PF12773.7 EPE32703.1 - 0.7 10.0 5.9 0.28 11.3 2.5 2.0 2 0 0 2 2 2 0 Double zinc ribbon FYVE PF01363.21 EPE32703.1 - 1.9 8.7 6.8 2.3 8.4 1.6 2.3 2 1 0 2 2 2 0 FYVE zinc finger SET PF00856.28 EPE32704.1 - 1.4e-09 38.5 0.2 1.2e-07 32.3 0.0 3.2 2 1 0 2 2 2 1 SET domain Tmemb_55A PF09788.9 EPE32704.1 - 0.021 13.9 0.1 0.036 13.1 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 55A FAM76 PF16046.5 EPE32704.1 - 0.97 8.7 5.1 0.19 11.1 0.3 2.3 2 0 0 2 2 2 0 FAM76 protein KilA-N PF04383.13 EPE32706.1 - 0.00053 19.8 0.0 0.013 15.3 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain CHRD PF07452.12 EPE32706.1 - 0.11 13.5 0.0 0.24 12.4 0.0 1.7 1 0 0 1 1 1 0 CHRD domain BTB PF00651.31 EPE32707.1 - 0.00094 19.4 0.0 0.0039 17.4 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain PAP2_3 PF14378.6 EPE32708.1 - 1.5e-26 93.2 18.4 1.7e-19 70.3 7.1 2.5 2 1 0 2 2 2 2 PAP2 superfamily PAP2_C PF14360.6 EPE32708.1 - 0.04 14.4 0.5 0.04 14.4 0.5 3.5 3 1 0 3 3 3 0 PAP2 superfamily C-terminal PAP2 PF01569.21 EPE32708.1 - 0.19 11.5 10.1 0.079 12.7 6.2 2.2 1 1 1 2 2 2 0 PAP2 superfamily Patatin PF01734.22 EPE32709.1 - 8.6e-26 91.4 0.0 4e-25 89.2 0.0 2.1 2 0 0 2 2 2 1 Patatin-like phospholipase zf-C3HC4 PF00097.25 EPE32709.1 - 0.0081 16.0 6.1 0.017 15.0 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE32709.1 - 0.018 15.0 5.6 0.05 13.6 5.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 EPE32709.1 - 0.11 12.9 6.9 0.23 11.8 6.9 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 EPE32709.1 - 0.37 10.8 6.5 0.79 9.7 6.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 EPE32709.1 - 0.47 10.4 6.9 1 9.3 6.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EPE32709.1 - 4.1 7.6 7.7 21 5.3 7.8 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING ABC_tran PF00005.27 EPE32710.1 - 7.8e-05 23.2 0.0 0.00021 21.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter zf-B_box PF00643.24 EPE32710.1 - 0.0047 17.0 5.7 0.0086 16.2 5.7 1.3 1 0 0 1 1 1 1 B-box zinc finger RsgA_GTPase PF03193.16 EPE32710.1 - 0.0059 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EPE32710.1 - 0.0083 16.2 0.1 0.033 14.3 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 EPE32710.1 - 0.016 15.4 0.3 0.038 14.1 0.3 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 EPE32710.1 - 0.028 14.9 0.2 0.082 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EPE32710.1 - 0.036 14.5 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EPE32710.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EPE32710.1 - 0.06 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EPE32710.1 - 0.085 13.0 0.2 0.34 11.1 0.2 2.0 2 1 0 2 2 2 0 AAA domain CEBP_ZZ PF16366.5 EPE32710.1 - 0.48 10.7 8.0 0.96 9.7 8.0 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain SRP_TPR_like PF17004.5 EPE32711.1 - 1.6e-22 79.7 0.2 3.9e-20 72.0 0.1 2.5 2 0 0 2 2 2 2 Putative TPR-like repeat SRP72 PF08492.12 EPE32711.1 - 6e-14 52.2 8.3 6e-14 52.2 8.3 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 EPE32711.1 - 1.6e-05 25.1 4.8 0.0055 16.9 0.8 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EPE32711.1 - 8.2e-05 23.0 17.2 0.45 11.1 0.0 6.7 4 2 1 6 6 6 2 Tetratricopeptide repeat GGA_N-GAT PF18308.1 EPE32711.1 - 0.0088 15.6 0.6 0.075 12.7 0.0 2.6 2 0 0 2 2 2 1 GGA N-GAT domain TPR_2 PF07719.17 EPE32711.1 - 0.091 12.9 12.3 44 4.6 0.9 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPE32711.1 - 0.98 9.8 9.5 51 4.2 0.6 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat SPO22 PF08631.10 EPE32711.1 - 1.1 8.7 4.1 1.4 8.3 0.0 3.1 5 0 0 5 5 5 0 Meiosis protein SPO22/ZIP4 like MFS_1 PF07690.16 EPE32713.1 - 4.4e-18 65.3 34.9 4.4e-18 65.3 34.9 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily N-Term_TEN PF11474.8 EPE32714.1 - 0.082 12.5 0.0 0.092 12.3 0.0 1.1 1 0 0 1 1 1 0 Telomerase reverse transcriptase TEN domain VirD1 PF07328.11 EPE32714.1 - 0.12 12.3 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 LPMO_10 PF03067.15 EPE32715.1 - 8e-09 36.4 0.4 1.1e-08 36.0 0.4 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_10 PF00331.20 EPE32717.1 - 5.4e-95 318.2 0.4 6.4e-95 317.9 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Amidoligase_2 PF12224.8 EPE32718.1 - 4.7e-25 88.7 0.0 7e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme Sugar_tr PF00083.24 EPE32719.1 - 3.6e-84 283.2 19.9 4.2e-84 283.0 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE32719.1 - 5.5e-17 61.7 39.4 1.6e-10 40.4 6.4 2.3 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 EPE32719.1 - 0.0015 17.5 5.8 0.0015 17.5 5.8 2.2 2 0 0 2 2 2 1 MFS_1 like family HET PF06985.11 EPE32720.1 - 5.6e-13 49.5 6.6 6.3e-10 39.6 1.9 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF924 PF06041.11 EPE32721.1 - 1.1e-43 149.5 0.0 1.3e-43 149.3 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) HSP90 PF00183.18 EPE32724.1 - 3.1e-221 735.8 29.8 4.1e-221 735.4 29.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EPE32724.1 - 1.2e-15 58.0 0.1 2.7e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EPE32724.1 - 7.9e-10 38.7 0.2 7.9e-10 38.7 0.2 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 EPE32724.1 - 0.044 13.8 1.7 0.067 13.2 0.2 2.0 2 0 0 2 2 2 0 Tumour suppressor protein DUF1676 PF07898.13 EPE32724.1 - 0.32 11.0 4.6 3.1 7.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) DUF2207 PF09972.9 EPE32727.1 - 0.025 13.3 2.7 0.067 11.9 2.7 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) ABC2_membrane_3 PF12698.7 EPE32727.1 - 0.038 13.1 4.8 0.08 12.0 4.9 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4791 PF16039.5 EPE32727.1 - 0.12 11.9 0.2 0.3 10.6 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4791) LapA_dom PF06305.11 EPE32727.1 - 0.14 12.0 0.1 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Insulin_TMD PF17870.1 EPE32727.1 - 0.18 11.9 3.2 3.7 7.7 0.6 2.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Sigma_reg_N PF13800.6 EPE32727.1 - 3.6 7.9 4.5 6.9 7.0 0.4 2.4 2 1 1 3 3 3 0 Sigma factor regulator N-terminal Lipase_GDSL_2 PF13472.6 EPE32729.1 - 1.8e-21 77.3 1.3 1.8e-21 77.3 1.3 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE32729.1 - 3.2e-06 27.3 0.0 5.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Peptidase_S8 PF00082.22 EPE32730.1 - 5.3e-31 108.0 22.2 9.3e-31 107.2 22.2 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EPE32730.1 - 1.1e-10 42.1 0.7 2e-10 41.2 0.7 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Septin PF00735.18 EPE32731.1 - 4.7e-24 85.1 0.1 1.2e-22 80.6 0.1 2.1 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EPE32731.1 - 4.7e-06 26.7 0.0 1.4e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EPE32731.1 - 0.0008 19.9 0.0 0.0023 18.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Roc PF08477.13 EPE32731.1 - 0.0018 18.5 0.1 0.0066 16.7 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EPE32731.1 - 0.0029 17.5 0.1 0.01 15.8 0.0 1.9 2 0 0 2 2 1 1 RsgA GTPase AAA_16 PF13191.6 EPE32731.1 - 0.0056 17.1 0.2 0.017 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 EPE32731.1 - 0.029 14.7 0.0 0.093 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain Dynamin_N PF00350.23 EPE32731.1 - 0.036 14.1 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 Dynamin family AAA_21 PF13304.6 EPE32731.1 - 0.039 13.8 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EPE32731.1 - 0.047 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EPE32731.1 - 0.048 13.4 0.1 0.16 11.7 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EPE32731.1 - 0.058 12.9 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 EPE32731.1 - 0.064 13.0 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain MCM PF00493.23 EPE32731.1 - 0.067 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_18 PF13238.6 EPE32731.1 - 0.07 13.7 0.3 0.44 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EPE32731.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EPE32731.1 - 0.12 11.9 0.0 0.64 9.5 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EPE32731.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 EPE32731.1 - 0.15 12.0 0.1 0.38 10.7 0.1 1.7 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 EPE32731.1 - 0.21 11.5 0.1 0.43 10.5 0.1 1.5 1 0 0 1 1 1 0 NTPase Plasmod_MYXSPDY PF07981.11 EPE32731.1 - 1.1 9.4 4.2 18 5.5 0.5 3.6 3 0 0 3 3 3 0 Plasmodium repeat_MYXSPDY Pkinase PF00069.25 EPE32732.1 - 2.9e-75 253.0 0.0 3.4e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE32732.1 - 3.3e-35 121.6 0.0 4.3e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EPE32732.1 - 8.5e-05 21.7 0.1 0.0012 17.9 0.1 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EPE32732.1 - 0.013 14.8 0.2 0.024 14.0 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPE32732.1 - 0.033 14.1 0.1 0.06 13.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA PF00004.29 EPE32733.1 - 1.4e-17 64.4 0.0 3.3e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPE32733.1 - 0.00088 19.6 0.1 0.025 14.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 EPE32733.1 - 0.028 14.8 0.0 0.075 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EPE32733.1 - 0.04 13.6 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EPE32733.1 - 0.075 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EPE32733.1 - 0.083 13.3 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ZYG-11_interact PF05884.12 EPE32733.1 - 0.097 12.1 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 RuvB_N PF05496.12 EPE32733.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Vps36_ESCRT-II PF11605.8 EPE32733.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 AAA_5 PF07728.14 EPE32733.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Methyltransf_11 PF08241.12 EPE32734.1 - 0.11 13.1 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Xan_ur_permease PF00860.20 EPE32735.1 - 6.4e-32 110.7 31.2 1.5e-31 109.5 31.2 1.6 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 EPE32735.1 - 0.014 15.8 3.2 0.014 15.8 3.2 3.2 4 0 0 4 4 4 0 Molybdate transporter of MFS superfamily Pox_A32 PF04665.12 EPE32735.1 - 0.39 10.1 0.6 0.62 9.5 0.6 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein HLH PF00010.26 EPE32737.1 - 1.7e-11 43.9 0.3 3e-11 43.1 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HAP1_N PF04849.13 EPE32737.1 - 0.018 14.2 0.2 0.028 13.6 0.2 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region YkyA PF10368.9 EPE32737.1 - 0.15 11.7 1.1 0.25 11.0 1.1 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein PAF-AH_p_II PF03403.13 EPE32738.1 - 1.5e-17 63.2 0.0 6.6e-09 34.8 0.0 2.3 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EPE32738.1 - 8.4e-08 31.4 0.0 4.9e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EPE32738.1 - 1.3e-05 24.6 0.0 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EPE32738.1 - 1.4e-05 25.0 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 EPE32738.1 - 0.00015 21.5 0.4 0.00093 18.9 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE32738.1 - 0.00093 19.9 0.1 0.0014 19.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 EPE32738.1 - 0.0011 18.0 0.6 0.0078 15.3 0.3 2.2 2 1 0 2 2 2 1 Chlorophyllase Abhydrolase_5 PF12695.7 EPE32738.1 - 0.0018 18.0 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lipase PF00151.19 EPE32738.1 - 0.0092 15.3 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 1 Lipase PGAP1 PF07819.13 EPE32738.1 - 0.058 13.1 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.18 EPE32738.1 - 0.18 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EPE32738.1 - 0.22 10.9 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family RIG-I_C-RD PF11648.8 EPE32739.1 - 0.11 12.7 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain of RIG-I AA_permease_2 PF13520.6 EPE32742.1 - 6.2e-54 183.4 51.2 7.7e-54 183.1 51.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE32742.1 - 1.7e-17 63.2 43.6 2.3e-17 62.8 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease DNA_pol_phi PF04931.13 EPE32743.1 - 0.22 9.6 25.6 0.0036 15.5 13.8 2.2 2 0 0 2 2 2 0 DNA polymerase phi Fungal_trans_2 PF11951.8 EPE32744.1 - 9.6e-10 37.8 0.1 1.1e-08 34.4 0.1 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain SAP PF02037.27 EPE32746.1 - 3.8e-14 52.0 0.0 7.7e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 EPE32746.1 - 3.7e-06 26.6 1.4 3.7e-06 26.6 1.4 2.2 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain PorB PF11565.8 EPE32746.1 - 0.0052 17.2 0.5 0.069 13.6 0.1 2.3 2 0 0 2 2 2 1 Alpha helical Porin B Methyltransf_11 PF08241.12 EPE32747.1 - 0.0006 20.4 0.0 0.0012 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE32747.1 - 0.0011 19.6 0.0 0.003 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_6 PF08030.12 EPE32748.1 - 1.4e-05 25.3 0.1 0.00071 19.7 0.1 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EPE32748.1 - 3.8e-05 24.3 0.0 0.00011 22.8 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EPE32748.1 - 0.085 13.2 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain HET PF06985.11 EPE32750.1 - 3.3e-28 98.9 0.2 3.5e-20 72.8 0.1 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Syndecan PF01034.20 EPE32751.1 - 0.0076 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain PTP_tm PF18861.1 EPE32751.1 - 0.045 13.8 0.1 0.095 12.7 0.0 1.6 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF347 PF03988.12 EPE32751.1 - 0.051 13.8 0.1 0.091 13.0 0.1 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) EphA2_TM PF14575.6 EPE32751.1 - 0.068 14.1 0.0 0.14 13.1 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 EPE32751.1 - 0.085 11.7 0.4 0.11 11.3 0.4 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4536 PF15055.6 EPE32751.1 - 0.28 11.5 1.2 0.78 10.0 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4536) Gram_pos_anchor PF00746.21 EPE32751.1 - 1.5 8.8 5.6 0.2 11.6 1.6 1.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif YjbE PF11106.8 EPE32751.1 - 2.7 8.2 7.9 0.55 10.5 0.3 2.6 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE DUF2613 PF11021.8 EPE32751.1 - 4.3 7.5 11.2 2.1 8.5 0.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) p450 PF00067.22 EPE32753.1 - 1.3e-53 182.4 0.0 1.6e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 EPE32754.1 - 1.2e-32 113.3 0.3 1.8e-32 112.7 0.3 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HK_sensor PF16750.5 EPE32754.1 - 0.16 12.3 0.0 0.39 11.0 0.0 1.6 1 1 0 1 1 1 0 Sensor domain of 2-component histidine kinase Dicty_CAR PF05462.11 EPE32755.1 - 5.4e-14 52.0 5.5 5.4e-14 52.0 5.5 1.4 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 EPE32755.1 - 1.5e-06 27.7 3.0 2.2e-06 27.2 3.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 EPE32755.1 - 8.7e-06 25.7 7.2 1.6e-05 24.7 7.2 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 TMEMspv1-c74-12 PF11044.8 EPE32755.1 - 0.094 12.7 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein mRNA_decap_C PF16741.5 EPE32757.1 - 0.1 11.9 0.2 0.23 10.8 0.2 1.5 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus DnaJ PF00226.31 EPE32758.1 - 3.6e-20 71.9 1.6 7.2e-20 70.9 1.6 1.6 1 0 0 1 1 1 1 DnaJ domain Laminin_G_3 PF13385.6 EPE32759.1 - 1.2e-19 70.9 2.3 2.5e-19 69.9 0.1 2.5 2 1 1 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 EPE32759.1 - 4.4e-08 33.8 0.1 1.3e-07 32.2 0.0 1.8 2 0 0 2 2 2 1 Laminin G domain Ricin_B_lectin PF00652.22 EPE32759.1 - 1e-06 29.0 0.0 0.00042 20.6 0.0 2.7 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain PLAT PF01477.23 EPE32759.1 - 3.8e-06 27.5 0.0 0.00017 22.1 0.0 2.9 3 0 0 3 3 3 1 PLAT/LH2 domain Laminin_G_1 PF00054.23 EPE32759.1 - 0.00076 19.7 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain HTH_7 PF02796.15 EPE32759.1 - 0.032 14.3 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase ATS3 PF06232.11 EPE32759.1 - 0.13 12.1 0.1 0.77 9.7 0.0 2.1 2 0 0 2 2 2 0 Embryo-specific protein 3, (ATS3) DUF2710 PF10921.8 EPE32759.1 - 0.19 12.2 0.5 1.6 9.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2710) PA-IIL PF07472.11 EPE32760.1 - 0.00069 19.9 3.8 0.0047 17.2 3.8 1.9 1 1 0 1 1 1 1 Fucose-binding lectin II (PA-IIL) DUF5114 PF17141.4 EPE32760.1 - 0.079 13.5 2.2 0.24 12.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5114) COesterase PF00135.28 EPE32761.1 - 1.5e-74 251.8 0.2 2.7e-73 247.6 0.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EPE32761.1 - 5.9e-05 22.6 0.1 0.0001 21.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EPE32761.1 - 0.043 13.7 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ceramidase_alk PF04734.13 EPE32763.1 - 1.2e-08 34.1 0.1 1.6e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal McyA_C PF12593.8 EPE32763.1 - 0.017 14.9 0.0 0.05 13.4 0.0 1.8 1 0 0 1 1 1 0 Microcystin synthetase C terminal GPI-anchored PF10342.9 EPE32764.1 - 1e-09 39.0 1.3 1.6e-09 38.4 0.1 1.7 1 1 1 2 2 2 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Zn_clus PF00172.18 EPE32765.1 - 3.3e-09 36.7 9.4 7.6e-09 35.6 9.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GGACT PF06094.12 EPE32765.1 - 0.031 14.9 0.0 0.056 14.1 0.0 1.4 1 0 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like DUF4391 PF14335.6 EPE32766.1 - 0.017 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Adaptin_N PF01602.20 EPE32767.1 - 6e-142 473.9 1.8 7.2e-142 473.6 1.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EPE32767.1 - 3e-22 79.0 0.1 8e-22 77.7 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EPE32767.1 - 9.1e-09 35.6 6.4 1.7e-05 24.9 0.0 4.2 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EPE32767.1 - 8.5e-06 26.1 1.0 0.045 14.2 0.0 3.4 3 0 0 3 3 3 2 HEAT repeats DUF3730 PF12530.8 EPE32767.1 - 0.00029 20.5 0.2 0.028 14.0 0.1 2.5 1 1 0 2 2 2 1 Protein of unknown function (DUF3730) HEAT PF02985.22 EPE32767.1 - 0.0005 20.1 1.1 6.5 7.3 0.1 4.3 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 EPE32767.1 - 0.2 12.2 1.2 64 4.2 0.0 4.3 5 0 0 5 5 5 0 HEAT-like repeat MBOAT PF03062.19 EPE32768.1 - 3.8e-36 125.2 23.2 3e-35 122.2 13.0 2.2 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Dec-1 PF04624.14 EPE32770.1 - 0.15 12.0 0.3 0.36 10.7 0.3 1.6 1 0 0 1 1 1 0 Dec-1 repeat DUF3818 PF12825.7 EPE32771.1 - 0.022 13.8 0.1 0.025 13.6 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Terminase_2 PF03592.16 EPE32771.1 - 0.033 14.6 0.1 0.045 14.2 0.1 1.2 1 0 0 1 1 1 0 Terminase small subunit DUF4470 PF14737.6 EPE32773.1 - 5.8e-11 42.4 0.0 1.6e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_11 PF13414.6 EPE32773.1 - 6e-10 38.6 0.5 1.2e-09 37.7 0.5 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 EPE32773.1 - 1.3e-07 31.2 0.1 2e-05 24.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EPE32773.1 - 0.00032 20.9 0.2 0.0021 18.3 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EPE32773.1 - 0.0021 18.5 0.3 0.0047 17.4 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EPE32773.1 - 0.0051 17.1 1.3 0.044 14.1 1.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EPE32773.1 - 0.0087 15.8 0.3 0.052 13.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPE32773.1 - 0.0098 16.5 0.1 0.025 15.2 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPE32773.1 - 0.027 15.3 0.3 1.3 10.1 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat RVT_N PF13655.6 EPE32773.1 - 0.054 13.8 0.7 0.15 12.3 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase TPR_8 PF13181.6 EPE32773.1 - 0.072 13.3 1.0 1.6 9.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_primase_lrg PF04104.14 EPE32774.1 - 7.8e-83 277.9 0.0 1.1e-82 277.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF812 PF05667.11 EPE32775.1 - 0.54 9.1 21.8 13 4.5 5.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Seryl_tRNA_N PF02403.22 EPE32775.1 - 2.4 8.4 25.5 0.28 11.4 7.4 3.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain 4HBT_2 PF13279.6 EPE32776.1 - 2.6e-23 82.8 0.0 3.8e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EPE32776.1 - 0.0041 17.5 0.0 0.0075 16.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily PP1c_bdg PF10488.9 EPE32776.1 - 0.016 14.7 1.3 0.15 11.5 0.8 2.0 2 0 0 2 2 2 0 Phosphatase-1 catalytic subunit binding region MRPL52 PF18699.1 EPE32776.1 - 0.067 13.4 0.8 0.12 12.6 0.8 1.3 1 0 0 1 1 1 0 Mitoribosomal protein mL52 Complex1_LYR PF05347.15 EPE32777.1 - 0.0013 18.8 0.1 0.0019 18.2 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EPE32777.1 - 0.016 16.0 0.0 0.017 15.8 0.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Methyltransf_25 PF13649.6 EPE32778.1 - 2.3e-13 50.7 0.0 5.4e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE32778.1 - 1.4e-08 35.3 0.0 3.2e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE32778.1 - 7.4e-07 29.1 0.0 1.4e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE32778.1 - 3.8e-06 26.8 0.0 1e-05 25.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE32778.1 - 2.7e-05 24.8 0.0 6.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE32778.1 - 0.0013 18.1 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EPE32778.1 - 0.26 11.3 1.9 2.3 8.2 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Exo_endo_phos PF03372.23 EPE32779.1 - 3e-12 46.6 0.2 1.1e-10 41.4 0.0 2.7 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 EPE32779.1 - 1.5e-07 31.6 0.3 0.013 15.9 0.1 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EPE32779.1 - 5.8e-07 29.2 0.2 0.0038 16.9 0.1 2.4 1 1 1 2 2 2 2 Leucine rich repeat Glyco_hydro_18 PF00704.28 EPE32780.1 - 6.9e-18 65.4 1.2 4.9e-17 62.6 0.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 DUF1272 PF06906.11 EPE32781.1 - 0.0028 17.7 0.3 0.032 14.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1272) zf-FPG_IleRS PF06827.14 EPE32781.1 - 0.12 12.3 0.3 0.12 12.3 0.3 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf_UBZ PF18439.1 EPE32781.1 - 0.64 9.7 3.7 8.8 6.0 0.6 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Apt1 PF10351.9 EPE32781.1 - 0.77 8.5 9.0 0.72 8.6 9.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Sec3_C PF09763.9 EPE32781.1 - 5.2 5.3 5.6 6 5.1 5.6 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 AAA_12 PF13087.6 EPE32782.1 - 3.2e-33 115.0 0.0 5.8e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EPE32782.1 - 7.7e-23 81.6 0.0 1.6e-13 51.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EPE32782.1 - 4.3e-08 33.6 0.0 1.3e-07 32.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 EPE32782.1 - 8e-06 25.6 0.0 2.2e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EPE32782.1 - 2e-05 24.5 0.0 0.00029 20.7 0.0 2.6 3 0 0 3 3 3 1 Helicase AAA_30 PF13604.6 EPE32782.1 - 7.7e-05 22.5 0.0 0.00029 20.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPE32782.1 - 0.0017 18.7 0.0 0.0055 17.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 EPE32782.1 - 0.0017 18.3 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 EPE32782.1 - 0.012 15.3 0.0 3.9 7.1 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EPE32782.1 - 0.019 14.2 0.0 0.43 9.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EPE32782.1 - 0.094 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE32782.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 EPE32782.1 - 0.18 11.3 0.0 0.45 9.9 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein TPR_12 PF13424.6 EPE32783.1 - 1.1e-16 60.9 0.0 1.4e-09 38.1 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EPE32783.1 - 3.8e-15 55.2 0.0 0.00013 21.7 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EPE32783.1 - 2.3e-05 24.0 0.0 0.003 17.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EPE32783.1 - 2.4e-05 24.1 0.1 0.042 13.9 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EPE32783.1 - 8.9e-05 23.0 0.1 0.014 16.2 0.0 2.5 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EPE32783.1 - 0.00012 21.9 0.0 0.0064 16.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EPE32783.1 - 0.00017 21.1 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_19 PF14559.6 EPE32783.1 - 0.0014 19.1 0.0 0.0051 17.3 0.0 1.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EPE32783.1 - 0.011 16.3 0.0 0.27 11.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1353 PF07087.11 EPE32783.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) TPR_8 PF13181.6 EPE32783.1 - 0.057 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPE32784.1 - 1.1e-20 73.7 1.2 3.9e-11 43.1 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EPE32784.1 - 2e-18 65.6 0.3 8.9e-05 22.2 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 EPE32784.1 - 1.2e-11 43.7 0.7 0.00012 21.9 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EPE32784.1 - 2.2e-11 43.0 3.5 0.00026 20.7 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EPE32784.1 - 5.2e-11 41.8 1.7 0.0023 17.9 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPE32784.1 - 1.5e-09 37.3 2.3 0.00092 19.3 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EPE32784.1 - 7.1e-08 32.2 0.4 8.9e-08 31.9 0.4 1.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_6 PF13174.6 EPE32784.1 - 8.7e-07 29.2 0.4 0.46 11.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EPE32784.1 - 1.1e-05 25.9 0.2 1.6 9.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EPE32784.1 - 3.1e-05 24.5 0.1 0.5 11.1 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.14 EPE32784.1 - 7.3e-05 23.0 0.2 0.066 13.9 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EPE32784.1 - 8.8e-05 22.1 0.3 0.28 10.9 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 EPE32784.1 - 0.0022 18.2 0.7 5.6 7.6 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EPE32784.1 - 0.0024 18.4 0.3 0.17 12.4 0.2 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 EPE32784.1 - 0.014 15.5 0.0 0.059 13.5 0.0 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain PPR PF01535.20 EPE32784.1 - 0.015 15.5 0.6 3.6 8.0 0.0 2.8 3 0 0 3 3 3 0 PPR repeat TPR_21 PF09976.9 EPE32784.1 - 0.02 14.6 0.5 1.8 8.2 0.1 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat-like domain Tcf25 PF04910.14 EPE32784.1 - 0.025 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 RPN6_N PF18055.1 EPE32784.1 - 0.057 13.8 0.0 0.18 12.2 0.0 1.8 1 1 1 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF2225 PF09986.9 EPE32784.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) APH PF01636.23 EPE32785.1 - 2.5e-09 37.4 0.0 1.1e-08 35.3 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Metallophos PF00149.28 EPE32787.1 - 3.4e-11 44.0 0.1 5.5e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPE32787.1 - 2e-05 24.9 0.2 0.00028 21.1 0.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPP_enzyme_N PF02776.18 EPE32788.1 - 6.9e-32 110.4 0.0 1.4e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EPE32788.1 - 1.1e-16 60.8 0.0 3.8e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EPE32788.1 - 3.2e-14 53.0 0.0 5.8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EPE32788.1 - 0.074 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase FAD_binding_2 PF00890.24 EPE32790.1 - 7.7e-30 104.3 0.2 5.6e-29 101.5 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPE32790.1 - 6.8e-12 45.6 0.4 6.8e-12 45.6 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE32790.1 - 3e-08 33.2 0.4 0.0079 15.5 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE32790.1 - 5.5e-07 28.6 3.4 0.0031 16.3 0.1 2.9 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 EPE32790.1 - 6e-05 22.6 1.2 0.00045 19.7 1.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPE32790.1 - 6.2e-05 22.4 0.5 0.057 12.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE32790.1 - 0.013 14.6 0.0 0.028 13.5 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 EPE32790.1 - 0.028 13.7 2.0 2.2 7.4 0.3 2.3 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 EPE32790.1 - 0.054 12.6 0.1 0.054 12.6 0.1 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A Fungal_trans PF04082.18 EPE32792.1 - 7.8e-11 41.5 3.7 1.3e-10 40.7 3.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE32792.1 - 1.3e-09 38.0 11.5 2.2e-09 37.3 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 EPE32793.1 - 8.8e-72 242.6 0.0 1.1e-71 242.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE32793.1 - 1.5e-05 24.9 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AA_permease PF00324.21 EPE32794.1 - 3.9e-124 414.9 43.6 4.4e-124 414.7 43.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE32794.1 - 2.7e-36 125.3 51.8 4e-36 124.8 50.9 1.6 1 1 0 1 1 1 1 Amino acid permease GCSF PF16647.5 EPE32794.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor TNFR_16_TM PF18422.1 EPE32795.1 - 0.043 13.8 0.2 0.39 10.7 0.0 2.5 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Metallophos PF00149.28 EPE32796.1 - 1.9e-17 64.4 0.2 3e-17 63.8 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPE32796.1 - 0.0019 18.4 0.0 0.043 14.0 0.0 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF2483 PF10656.9 EPE32796.1 - 0.15 12.2 0.0 14 5.9 0.0 2.4 1 1 1 2 2 2 0 Hypothetical protein of unknown function (DUF2483) Hydrolase_4 PF12146.8 EPE32798.1 - 1.5e-49 168.5 0.0 1.7e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPE32798.1 - 1.8e-13 51.6 0.6 2.2e-13 51.3 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE32798.1 - 6.7e-12 45.6 0.1 1.7e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 EPE32798.1 - 0.0023 17.6 0.1 0.21 11.2 0.0 2.2 2 0 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.16 EPE32798.1 - 0.019 14.8 0.0 0.58 9.9 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 EPE32798.1 - 0.045 13.6 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 EPE32798.1 - 0.075 11.9 0.1 0.23 10.4 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 EPE32798.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein RRG8 PF17068.5 EPE32799.1 - 0.00015 21.3 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 Required for respiratory growth protein 8 mitochondrial CLP_protease PF00574.23 EPE32800.1 - 3.8e-77 258.3 0.0 4.5e-77 258.1 0.0 1.0 1 0 0 1 1 1 1 Clp protease Tugs PF17840.1 EPE32800.1 - 0.079 13.2 0.5 0.16 12.2 0.5 1.4 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain GspL_C PF12693.7 EPE32801.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 GspL periplasmic domain YL1 PF05764.13 EPE32807.1 - 0.0012 19.0 4.5 0.0012 19.0 4.5 2.0 2 0 0 2 2 2 1 YL1 nuclear protein Glyco_hydro_43 PF04616.14 EPE32809.1 - 8.6e-54 182.8 3.2 1e-53 182.5 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 EPE32809.1 - 3.8e-38 130.6 1.5 7.6e-38 129.6 1.5 1.5 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 EPE32809.1 - 3e-08 33.8 0.3 6.9e-08 32.6 0.3 1.6 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 EPE32809.1 - 0.039 13.5 3.0 0.026 14.1 0.9 1.7 2 1 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain Fungal_trans_2 PF11951.8 EPE32810.1 - 3.6e-35 121.5 1.8 5.7e-33 114.3 1.8 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE32810.1 - 1.2e-09 38.1 5.0 2.3e-09 37.2 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAD_2 PF13419.6 EPE32811.1 - 8.2e-06 26.0 0.0 2.3e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPE32811.1 - 0.037 14.3 0.0 0.12 12.7 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase GMC_oxred_N PF00732.19 EPE32812.1 - 3.8e-55 187.4 0.0 4.9e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE32812.1 - 3e-36 125.1 0.0 5.2e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.6 EPE32812.1 - 1.7e-07 30.8 0.2 0.0059 15.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE32812.1 - 3.8e-07 30.0 0.0 6.5e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE32812.1 - 1.9e-05 24.1 0.2 0.027 13.7 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EPE32812.1 - 0.00013 21.2 0.4 0.063 12.4 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.27 EPE32812.1 - 0.00024 21.6 0.3 1.2 9.7 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE32812.1 - 0.00036 19.7 0.2 0.017 14.2 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EPE32812.1 - 0.00045 19.4 0.6 0.011 14.8 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 EPE32812.1 - 0.001 19.1 1.0 0.5 10.3 0.3 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EPE32812.1 - 0.001 19.2 0.5 0.0025 18.0 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EPE32812.1 - 0.016 14.1 0.5 0.034 13.0 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 EPE32812.1 - 0.062 12.5 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EPE32812.1 - 0.17 10.6 0.3 0.43 9.2 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein NmrA PF05368.13 EPE32813.1 - 1.1e-33 116.7 2.1 1.5e-33 116.3 2.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE32813.1 - 2.8e-10 40.4 0.3 5.5e-10 39.4 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EPE32813.1 - 3.5e-05 22.9 1.0 6.4e-05 22.1 0.6 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EPE32813.1 - 6.2e-05 23.3 0.1 0.00012 22.4 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EPE32813.1 - 0.00014 21.4 0.1 0.0011 18.4 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EPE32813.1 - 0.00025 21.0 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 EPE32813.1 - 0.0011 19.3 0.3 0.0034 17.8 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EPE32813.1 - 0.0035 16.5 0.5 0.0052 16.0 0.5 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DXP_reductoisom PF02670.16 EPE32813.1 - 0.0086 16.8 0.4 0.021 15.6 0.4 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase GDP_Man_Dehyd PF16363.5 EPE32813.1 - 0.015 14.7 0.1 0.023 14.1 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPE32813.1 - 0.047 12.8 0.0 0.091 11.9 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein Chromate_transp PF02417.15 EPE32815.1 - 6.6e-61 205.1 37.8 5.1e-33 114.4 15.7 2.5 3 0 0 3 3 3 2 Chromate transporter TMP_2 PF06791.13 EPE32815.1 - 2.7 7.6 5.1 4.4 6.9 1.1 2.1 2 0 0 2 2 2 0 Prophage tail length tape measure protein NUDIX PF00293.28 EPE32816.1 - 6.5e-11 42.4 0.0 1.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain ZZ PF00569.17 EPE32816.1 - 0.00015 21.5 6.5 0.00026 20.7 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Tnp_zf-ribbon_2 PF13842.6 EPE32816.1 - 0.3 11.9 7.7 0.54 11.1 7.7 1.4 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Peptidase_M36 PF02128.15 EPE32817.1 - 1.1e-156 521.7 6.9 1.3e-156 521.4 6.9 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EPE32817.1 - 1e-17 63.6 4.6 3.3e-17 62.1 4.6 1.9 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Sugar_tr PF00083.24 EPE32818.1 - 6.9e-83 279.0 25.6 8.7e-83 278.7 25.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE32818.1 - 4.3e-27 95.0 37.9 1e-26 93.7 37.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE32818.1 - 2.4e-05 23.0 5.7 2.4e-05 23.0 5.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1772 PF08592.11 EPE32818.1 - 0.14 12.5 2.2 9.6 6.5 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Utp13 PF08625.11 EPE32820.1 - 2.1e-52 176.8 1.1 3.5e-52 176.1 1.1 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 EPE32820.1 - 7.6e-52 172.2 18.9 5e-05 24.0 0.7 11.5 10 2 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE32820.1 - 2.3e-14 53.5 4.4 0.51 10.7 0.1 8.2 6 1 2 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EPE32820.1 - 1.2e-07 30.9 2.4 0.052 12.3 0.0 5.9 4 3 1 6 6 6 2 Nup133 N terminal like Nup160 PF11715.8 EPE32820.1 - 8.8e-05 21.3 10.7 1.8 7.1 0.0 6.3 4 3 4 8 8 8 2 Nucleoporin Nup120/160 SRP-alpha_N PF04086.13 EPE32820.1 - 0.0017 18.4 0.3 0.0028 17.6 0.3 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal NQRA PF05896.11 EPE32820.1 - 0.011 15.2 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) PALB2_WD40 PF16756.5 EPE32820.1 - 0.025 13.5 1.0 2.3 7.1 0.1 2.8 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 EPE32820.1 - 0.09 13.3 1.7 15 6.3 0.1 3.9 2 1 0 2 2 2 0 PQQ-like domain WD40_like PF17005.5 EPE32820.1 - 0.15 11.3 0.0 1e+02 2.0 0.0 3.7 4 0 0 4 4 4 0 WD40-like domain MFS_1 PF07690.16 EPE32821.1 - 2.9e-35 121.8 29.5 2.9e-35 121.8 29.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.6 EPE32821.1 - 0.58 10.7 2.4 0.88 10.1 0.1 2.5 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) F-box PF00646.33 EPE32822.1 - 0.00036 20.3 0.0 0.00036 20.3 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EPE32822.1 - 0.015 15.2 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like Peptidase_M20 PF01546.28 EPE32823.1 - 4.3e-23 82.1 0.1 7.3e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EPE32823.1 - 9.3e-15 54.5 0.7 1.9e-14 53.5 0.2 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain DUF3883 PF13020.6 EPE32824.1 - 2.1e-05 24.5 0.0 7.5e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3883) HrpB1_HrpK PF09613.10 EPE32824.1 - 0.019 14.6 0.1 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) HSP70 PF00012.20 EPE32825.1 - 2.6e-10 39.1 0.0 4.6e-09 35.0 0.0 2.3 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EPE32825.1 - 6e-07 28.6 0.1 0.004 16.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EPE32825.1 - 0.0089 15.8 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain APG6_N PF17675.1 EPE32826.1 - 0.0005 20.6 21.1 0.0005 20.6 21.1 1.8 2 0 0 2 2 2 1 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 EPE32826.1 - 0.0045 17.0 15.8 0.0089 16.1 15.8 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF720 PF05302.11 EPE32826.1 - 0.59 10.0 12.4 4.7 7.1 3.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF720) DUF3450 PF11932.8 EPE32826.1 - 1.6 8.0 23.9 0.29 10.4 8.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 EPE32826.1 - 9.6 4.0 8.4 13 3.5 8.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4337 PF14235.6 EPE32826.1 - 9.7 6.3 16.1 4.6 7.3 13.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Ank_2 PF12796.7 EPE32827.1 - 3.3e-64 213.5 3.7 5.2e-11 43.0 0.0 7.4 3 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.30 EPE32827.1 - 1e-41 139.6 11.8 2e-05 24.8 0.0 13.4 14 0 0 14 14 14 9 Ankyrin repeat Ank_4 PF13637.6 EPE32827.1 - 1.3e-38 130.9 2.6 8.7e-06 26.2 0.1 10.9 5 3 7 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE32827.1 - 5.6e-36 118.5 6.6 0.00038 20.7 0.0 13.2 13 2 1 14 14 14 8 Ankyrin repeat Ank_5 PF13857.6 EPE32827.1 - 9.3e-29 99.1 7.0 0.0012 19.1 0.1 11.7 6 2 6 12 12 12 8 Ankyrin repeats (many copies) Glyco_transf_22 PF03901.17 EPE32828.1 - 1.6e-75 254.9 18.8 1.9e-75 254.7 18.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aminotran_3 PF00202.21 EPE32829.1 - 1.2e-121 406.2 0.0 1.4e-121 406.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EPE32829.1 - 7.5e-05 22.2 0.0 0.00015 21.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EPE32829.1 - 0.0062 15.7 0.0 0.0095 15.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DUF3543 PF12063.8 EPE32830.1 - 1.5e-87 293.1 0.0 2.7e-87 292.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EPE32830.1 - 6.9e-64 215.7 0.0 1.3e-63 214.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE32830.1 - 3.8e-43 147.7 0.0 7.9e-43 146.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EPE32830.1 - 0.04 12.9 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 EPE32830.1 - 0.29 9.8 0.0 0.29 9.8 0.0 1.9 2 1 0 2 2 2 0 Fungal protein kinase CMAS PF02353.20 EPE32831.1 - 1.5e-59 201.6 0.1 2.4e-59 200.9 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase EF-hand_4 PF12763.7 EPE32831.1 - 8.9e-24 83.4 0.0 1.6e-12 47.3 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Methyltransf_23 PF13489.6 EPE32831.1 - 7.4e-11 42.1 0.0 1.6e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE32831.1 - 1.4e-09 38.4 0.0 3.4e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE32831.1 - 2.2e-08 34.7 0.0 7.8e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE32831.1 - 0.0035 18.0 0.0 0.017 15.9 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain EF-hand_7 PF13499.6 EPE32831.1 - 0.0072 16.7 0.1 2.5 8.6 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain pair DUF1720 PF08226.11 EPE32831.1 - 0.0099 16.3 14.6 0.0099 16.3 14.6 7.9 5 2 1 7 7 7 3 Domain of unknown function (DUF1720) Zn_clus PF00172.18 EPE32832.1 - 0.0007 19.7 6.1 0.0017 18.4 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RWP-RK PF02042.15 EPE32832.1 - 0.047 13.7 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 RWP-RK domain CBM_4_9 PF02018.17 EPE32834.1 - 0.00076 19.8 0.6 1.5 9.1 0.1 2.8 2 2 0 2 2 2 2 Carbohydrate binding domain CPT PF07931.12 EPE32839.1 - 0.09 12.6 0.7 5.8 6.7 0.2 3.1 2 2 2 4 4 4 0 Chloramphenicol phosphotransferase-like protein DUF4795 PF16043.5 EPE32840.1 - 0.01 15.5 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Baculo_PEP_C PF04513.12 EPE32840.1 - 0.022 14.8 1.3 0.062 13.3 0.3 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GBR2_CC PF18455.1 EPE32840.1 - 0.023 14.8 0.1 3.2 7.9 0.0 2.8 2 0 0 2 2 2 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain Prominin PF05478.11 EPE32840.1 - 0.051 11.5 0.3 0.079 10.9 0.3 1.2 1 0 0 1 1 1 0 Prominin Pim PF16765.5 EPE32840.1 - 0.052 13.7 0.8 0.29 11.3 0.2 2.5 3 0 0 3 3 3 0 Pesticin immunity protein ApoLp-III PF07464.11 EPE32840.1 - 0.063 13.4 1.9 0.11 12.5 1.9 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF1640 PF07798.11 EPE32840.1 - 0.089 12.8 1.1 0.17 11.9 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) MISS PF15822.5 EPE32843.1 - 0.13 12.1 0.8 0.15 11.9 0.8 1.0 1 0 0 1 1 1 0 MAPK-interacting and spindle-stabilising protein-like DUF1840 PF08895.11 EPE32846.1 - 1.9 8.9 4.5 0.9 9.9 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) WD40 PF00400.32 EPE32848.1 - 4.8e-22 77.8 16.3 8.8e-08 32.7 0.2 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.12 EPE32848.1 - 6.8e-18 64.9 0.1 1.2e-17 64.2 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ank_2 PF12796.7 EPE32851.1 - 7.4e-56 186.7 9.9 3.3e-11 43.6 0.0 7.3 1 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE32851.1 - 1.8e-45 152.7 9.5 2.1e-07 31.4 0.0 9.4 3 2 7 10 10 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE32851.1 - 6.3e-45 150.6 13.7 2e-08 34.4 0.0 10.0 5 2 6 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 EPE32851.1 - 6e-41 137.1 8.2 5.1e-05 23.5 0.0 11.7 12 0 0 12 12 12 7 Ankyrin repeat Ank_3 PF13606.6 EPE32851.1 - 6.5e-34 112.1 2.4 0.0074 16.7 0.0 12.6 12 0 0 12 12 11 7 Ankyrin repeat HET PF06985.11 EPE32851.1 - 8.5e-11 42.4 4.4 1.2e-08 35.4 0.1 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 EPE32851.1 - 1e-05 25.5 0.0 3.5e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EPE32851.1 - 1.4e-05 25.6 0.0 0.00075 19.9 0.0 3.6 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 EPE32851.1 - 0.00039 20.7 0.0 0.0044 17.3 0.0 2.6 1 1 1 2 2 2 1 AAA domain NB-ARC PF00931.22 EPE32851.1 - 0.00094 18.4 0.4 0.002 17.3 0.4 1.5 1 0 0 1 1 1 1 NB-ARC domain RNA_helicase PF00910.22 EPE32851.1 - 0.014 15.8 0.1 0.17 12.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 EPE32851.1 - 0.046 14.1 0.0 0.22 11.9 0.0 2.3 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EPE32851.1 - 0.061 13.9 0.0 3.7 8.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EPE32851.1 - 0.14 11.9 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.23 EPE32852.1 - 8.8e-46 156.2 0.0 2.2e-44 151.6 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE32852.1 - 4e-16 59.3 0.0 1.8e-15 57.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE32852.1 - 3.7e-07 30.3 0.0 8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EPE32852.1 - 1.6e-06 27.8 13.0 1.6e-06 27.8 13.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPE32852.1 - 6.6e-05 22.7 11.0 6.6e-05 22.7 11.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE32852.1 - 0.0001 22.6 12.5 0.0001 22.6 12.5 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPE32852.1 - 0.00016 21.5 11.4 0.00016 21.5 11.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 EPE32852.1 - 0.0014 17.6 0.0 0.0033 16.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 AT_hook PF02178.19 EPE32852.1 - 1.1 9.4 6.6 0.39 10.8 0.5 2.9 2 0 0 2 2 2 0 AT hook motif LRR_6 PF13516.6 EPE32853.1 - 2.8e-06 26.9 5.6 0.083 13.0 0.0 5.1 4 0 0 4 4 4 2 Leucine Rich repeat DUF4428 PF14471.6 EPE32853.1 - 0.00089 19.1 0.4 0.0023 17.8 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) LRR_4 PF12799.7 EPE32853.1 - 0.001 19.4 11.2 2.7 8.6 0.3 5.8 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EPE32853.1 - 0.013 15.3 3.5 0.79 9.5 0.1 4.1 3 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 EPE32853.1 - 1.3 9.9 7.3 62 4.7 0.0 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat Zw10 PF06248.13 EPE32854.1 - 3.2e-06 26.0 1.8 4.4e-06 25.5 0.4 1.8 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 EPE32854.1 - 0.0037 17.0 0.1 0.0083 15.9 0.1 1.6 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Peptidase_M16_C PF05193.21 EPE32855.1 - 1.2e-16 61.3 0.0 5.3e-14 52.6 0.0 3.2 3 1 1 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EPE32855.1 - 1e-06 28.8 0.0 1.1e-05 25.5 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 EPE32855.1 - 0.58 9.2 2.0 2.9 6.9 1.2 2.3 2 0 0 2 2 2 0 Peptidase M16C associated DUF1179 PF06678.11 EPE32856.1 - 0.1 12.6 1.4 0.22 11.5 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Pro_isomerase PF00160.21 EPE32857.1 - 4.1e-48 163.6 0.6 5.4e-48 163.2 0.6 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.22 EPE32858.1 - 0.00037 20.9 0.6 0.0009 19.6 0.6 1.9 1 1 0 1 1 1 1 Ribosomal protein S13/S18 HET PF06985.11 EPE32859.1 - 3.3e-27 95.6 0.0 6.9e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cu_bind_like PF02298.17 EPE32861.1 - 3.9e-05 23.6 0.1 9e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Plastocyanin-like domain E1-E2_ATPase PF00122.20 EPE32862.1 - 2.2e-45 154.4 3.8 8.4e-45 152.5 3.8 2.1 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EPE32862.1 - 6e-27 95.3 0.0 9.1e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EPE32862.1 - 8.8e-09 35.7 0.0 3e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF4234 PF14018.6 EPE32862.1 - 2.2 8.5 6.5 0.26 11.4 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Bactofilin PF04519.13 EPE32863.1 - 2e-09 37.6 16.3 1e-05 25.7 4.7 3.9 1 1 4 5 5 5 5 Polymer-forming cytoskeletal FapA PF03961.13 EPE32863.1 - 0.00095 17.9 33.5 0.003 16.2 4.3 4.2 1 1 2 4 4 4 4 Flagellar Assembly Protein A DUF748 PF05359.11 EPE32863.1 - 0.0027 17.9 1.6 3.5 7.8 0.0 4.5 4 1 0 4 4 4 1 Domain of Unknown Function (DUF748) Qn_am_d_aII PF14930.6 EPE32863.1 - 0.11 12.9 2.0 8.4 6.8 0.1 3.4 1 1 1 3 3 3 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II HET PF06985.11 EPE32864.1 - 1e-27 97.3 0.0 1.8e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2 PF00096.26 EPE32865.1 - 0.0028 18.0 7.3 0.024 15.1 2.9 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EPE32865.1 - 0.035 14.3 0.2 0.048 13.8 0.2 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 EPE32865.1 - 0.05 14.1 0.2 0.05 14.1 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 EPE32865.1 - 2.2 8.1 5.9 8.3 6.3 0.1 2.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 EPE32865.1 - 4.7 8.3 5.9 14 6.9 2.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Aspzincin_M35 PF14521.6 EPE32866.1 - 1.5e-32 113.1 5.4 1.5e-32 113.1 5.4 2.0 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 EPE32866.1 - 1.9e-25 89.5 21.8 4.2e-25 88.4 21.8 1.4 1 1 0 1 1 1 1 Deuterolysin metalloprotease (M35) family GPHR_N PF12537.8 EPE32866.1 - 0.12 12.4 5.3 1.7 8.8 0.5 2.5 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal NAD_binding_10 PF13460.6 EPE32867.1 - 7.8e-10 38.9 0.0 3.8e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EPE32867.1 - 1.1e-05 25.2 0.1 2.5e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EPE32867.1 - 5.7e-05 22.7 0.0 0.00016 21.2 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE32867.1 - 6.4e-05 22.1 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EPE32867.1 - 0.03 13.4 0.1 0.063 12.4 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EPE32867.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Zn_clus PF00172.18 EPE32869.1 - 1.3e-07 31.6 14.9 4e-07 30.0 9.3 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 EPE32870.1 - 7.6e-23 81.0 2.4 2.2e-22 79.5 2.4 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE32870.1 - 1.3e-14 54.4 2.2 3.8e-14 52.8 2.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE32870.1 - 4.8e-08 33.1 1.1 7.1e-08 32.6 0.1 1.7 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 EPE32870.1 - 0.011 15.6 0.7 0.02 14.8 0.7 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Methyltransf_31 PF13847.6 EPE32870.1 - 0.048 13.5 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.7 EPE32873.1 - 1.6e-50 169.6 6.6 3e-08 34.1 0.0 7.7 3 1 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE32873.1 - 2.8e-36 123.4 11.6 4.6e-08 33.4 0.0 10.1 6 3 4 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE32873.1 - 1.2e-30 105.2 11.8 1e-06 28.9 0.0 11.1 8 3 4 12 12 12 7 Ankyrin repeats (many copies) Ank PF00023.30 EPE32873.1 - 4.4e-29 99.6 16.5 0.042 14.3 0.0 11.8 11 1 1 12 12 12 9 Ankyrin repeat Ank_3 PF13606.6 EPE32873.1 - 1.9e-27 92.2 16.6 0.0013 19.0 0.0 13.5 15 1 0 15 15 15 6 Ankyrin repeat adh_short PF00106.25 EPE32874.1 - 3.7e-18 65.7 0.1 5.5e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE32874.1 - 4e-08 33.1 0.0 5.8e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE32874.1 - 5.7e-07 29.6 0.1 8.5e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE32874.1 - 0.0064 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 EPE32875.1 - 2.7e-12 46.3 0.1 4.5e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 EPE32876.1 - 8.2e-85 285.3 17.2 9.5e-85 285.1 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE32876.1 - 5.4e-13 48.6 24.0 5.4e-13 48.6 24.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EPE32876.1 - 8.8e-05 22.0 2.1 8.8e-05 22.0 2.1 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB NUMOD3 PF07460.11 EPE32879.1 - 0.13 12.6 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) Peptidase_M36 PF02128.15 EPE32881.1 - 1.3e-152 508.3 3.2 1.7e-152 507.9 3.2 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EPE32881.1 - 3.8e-18 65.0 2.1 8.7e-18 63.9 2.1 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif HET PF06985.11 EPE32882.1 - 1.4e-19 70.9 2.9 6.1e-16 59.1 2.1 3.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.11 EPE32883.1 - 7e-23 81.6 0.0 1.6e-22 80.4 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Securin PF04856.13 EPE32884.1 - 0.0025 17.8 3.8 0.007 16.4 1.8 2.7 1 1 1 2 2 2 1 Securin sister-chromatid separation inhibitor LEAP-2 PF07359.11 EPE32884.1 - 0.19 11.5 0.8 1.1 9.2 0.2 2.3 2 0 0 2 2 2 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Tropomyosin_1 PF12718.7 EPE32885.1 - 1.1e-20 74.2 22.9 1.3e-20 74.0 22.9 1.0 1 0 0 1 1 1 1 Tropomyosin like ATG16 PF08614.11 EPE32885.1 - 2.4e-05 24.7 16.7 0.0014 18.9 4.4 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) GAS PF13851.6 EPE32885.1 - 0.00015 21.2 23.0 0.00054 19.4 17.6 2.0 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.20 EPE32885.1 - 0.00016 21.2 22.9 0.00044 19.7 22.9 1.7 1 1 0 1 1 1 1 Tropomyosin Prefoldin_2 PF01920.20 EPE32885.1 - 0.0019 18.1 18.5 0.0077 16.2 2.4 2.7 1 1 1 2 2 2 2 Prefoldin subunit Cep57_CLD_2 PF14197.6 EPE32885.1 - 0.002 18.1 5.1 0.55 10.4 0.1 2.9 1 1 2 3 3 3 2 Centrosome localisation domain of PPC89 PspA_IM30 PF04012.12 EPE32885.1 - 0.0028 17.3 16.8 0.067 12.8 4.9 2.2 1 1 1 2 2 2 2 PspA/IM30 family TMF_DNA_bd PF12329.8 EPE32885.1 - 0.0032 17.4 20.1 0.01 15.8 1.1 3.5 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 EPE32885.1 - 0.0038 17.4 20.4 0.0099 16.0 7.7 2.1 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus TRAF_BIRC3_bd PF16673.5 EPE32885.1 - 0.0052 16.6 14.1 0.24 11.2 3.5 3.6 2 2 1 3 3 3 2 TNF receptor-associated factor BIRC3 binding domain BLOC1_2 PF10046.9 EPE32885.1 - 0.0065 16.7 13.1 0.3 11.4 3.0 2.8 2 1 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.21 EPE32885.1 - 0.0077 16.3 12.6 0.014 15.5 1.6 3.0 2 2 1 3 3 3 1 bZIP transcription factor Taxilin PF09728.9 EPE32885.1 - 0.01 15.0 4.5 0.01 15.0 4.5 2.1 1 1 0 1 1 1 0 Myosin-like coiled-coil protein ADIP PF11559.8 EPE32885.1 - 0.014 15.5 15.0 0.12 12.5 3.9 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 EPE32885.1 - 0.017 15.2 5.0 0.017 15.2 5.0 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 EPE32885.1 - 0.029 13.3 23.7 0.21 10.4 12.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Phage_GP20 PF06810.11 EPE32885.1 - 0.031 14.1 20.3 0.21 11.4 7.2 2.7 1 1 2 3 3 3 0 Phage minor structural protein GP20 LPP PF04728.13 EPE32885.1 - 0.039 14.3 0.4 0.039 14.3 0.4 3.0 3 1 0 3 3 2 0 Lipoprotein leucine-zipper CC2-LZ PF16516.5 EPE32885.1 - 0.044 14.2 15.4 0.2 12.0 5.3 2.7 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator YabA PF06156.13 EPE32885.1 - 0.047 14.3 10.9 1.3 9.7 1.1 2.3 2 0 0 2 2 2 0 Initiation control protein YabA DUF4988 PF16378.5 EPE32885.1 - 0.12 12.0 4.2 0.91 9.2 1.5 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF1664 PF07889.12 EPE32885.1 - 0.13 12.3 9.6 1.3 9.1 1.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 EPE32885.1 - 0.14 12.6 8.7 1.9 8.9 1.0 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Uds1 PF15456.6 EPE32885.1 - 0.15 12.3 10.2 0.23 11.6 10.0 1.6 1 1 0 1 1 1 0 Up-regulated During Septation FAA_hydro_N_2 PF18288.1 EPE32885.1 - 0.18 12.2 3.2 0.22 11.9 0.2 2.3 2 1 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 CLZ PF16526.5 EPE32885.1 - 0.2 12.1 11.4 1.5 9.3 3.3 2.9 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF16 PF01519.16 EPE32885.1 - 0.2 12.2 15.8 0.4 11.2 3.3 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 DHR10 PF18595.1 EPE32885.1 - 0.21 11.7 22.0 0.62 10.1 8.0 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Phage_lysozyme2 PF18013.1 EPE32885.1 - 0.22 11.6 4.6 0.16 12.0 3.2 1.5 1 1 0 1 1 1 0 Phage tail lysozyme DUF812 PF05667.11 EPE32885.1 - 0.22 10.4 23.0 0.28 10.0 23.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Calici_MSP PF05752.11 EPE32885.1 - 0.26 11.1 4.1 0.16 11.8 2.0 1.6 1 1 1 2 2 2 0 Calicivirus minor structural protein Fib_alpha PF08702.10 EPE32885.1 - 0.29 11.3 12.4 0.16 12.2 7.6 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Spc29 PF17082.5 EPE32885.1 - 0.3 10.9 7.8 3.3 7.5 0.7 2.3 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF4795 PF16043.5 EPE32885.1 - 0.35 10.4 16.0 0.8 9.3 16.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Wtap PF17098.5 EPE32885.1 - 0.42 10.5 9.9 1.9 8.4 0.7 2.7 1 1 0 2 2 2 0 WTAP/Mum2p family PRKG1_interact PF15898.5 EPE32885.1 - 0.45 11.4 15.1 0.4 11.6 3.7 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF2514 PF10721.9 EPE32885.1 - 0.48 10.4 9.3 1.2 9.1 9.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) GPS2_interact PF15784.5 EPE32885.1 - 0.49 10.9 10.5 0.99 9.9 3.5 2.8 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain Spectrin PF00435.21 EPE32885.1 - 0.5 10.9 17.9 2.2 8.8 5.3 2.7 1 1 1 2 2 2 0 Spectrin repeat T2SSM PF04612.12 EPE32885.1 - 0.55 10.3 8.4 1.2 9.2 0.4 2.5 1 1 2 3 3 2 0 Type II secretion system (T2SS), protein M CENP-Q PF13094.6 EPE32885.1 - 0.56 10.4 17.3 0.75 10.0 5.2 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4200 PF13863.6 EPE32885.1 - 0.58 10.6 22.4 6.7 7.1 12.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Fzo_mitofusin PF04799.13 EPE32885.1 - 0.58 9.7 8.7 1.2 8.7 1.1 2.4 1 1 1 2 2 2 0 fzo-like conserved region DUF4407 PF14362.6 EPE32885.1 - 0.69 9.2 17.5 1.7 8.0 4.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.9 EPE32885.1 - 0.73 9.8 19.6 2.5 8.0 6.2 2.5 1 1 2 3 3 3 0 Axonemal dynein light chain HrpB7 PF09486.10 EPE32885.1 - 0.78 10.1 13.4 3.4 8.0 12.6 2.3 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Nmad5 PF18757.1 EPE32885.1 - 0.85 9.8 10.6 1.1 9.5 10.6 1.1 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 TSC22 PF01166.18 EPE32885.1 - 0.98 9.8 8.9 0.16 12.3 1.4 3.1 1 1 0 2 2 2 0 TSC-22/dip/bun family SlyX PF04102.12 EPE32885.1 - 1.1 10.0 15.2 0.98 10.1 0.5 4.0 2 2 0 3 3 3 0 SlyX DUF4140 PF13600.6 EPE32885.1 - 1.1 9.7 14.0 5.7 7.5 5.0 2.7 2 2 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Seryl_tRNA_N PF02403.22 EPE32885.1 - 1.1 9.5 18.2 0.25 11.6 2.2 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 EPE32885.1 - 1.2 9.7 28.4 0.91 10.1 19.0 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 EPE32885.1 - 1.5 8.3 10.0 1.9 8.0 10.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Uso1_p115_C PF04871.13 EPE32885.1 - 1.7 9.0 24.1 1 9.8 8.4 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Syntaxin-6_N PF09177.11 EPE32885.1 - 1.8 9.2 11.9 6.3 7.4 3.6 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ERM PF00769.19 EPE32885.1 - 1.8 8.3 23.3 0.047 13.5 6.4 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3450 PF11932.8 EPE32885.1 - 1.8 7.8 20.7 2.3 7.5 5.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMCO5 PF14992.6 EPE32885.1 - 2 7.9 15.7 2.9 7.4 15.7 1.3 1 0 0 1 1 1 0 TMCO5 family HCMV_UL139 PF12507.8 EPE32885.1 - 2.1 8.8 10.0 37 4.7 4.7 3.0 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein KLRAQ PF10205.9 EPE32885.1 - 2.1 8.6 13.4 2.8 8.3 3.5 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein XhlA PF10779.9 EPE32885.1 - 2.3 8.5 12.9 0.9 9.8 3.2 3.0 2 2 2 4 4 4 0 Haemolysin XhlA Jnk-SapK_ap_N PF09744.9 EPE32885.1 - 2.5 8.3 20.8 1.2 9.4 6.8 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SOGA PF11365.8 EPE32885.1 - 2.6 9.3 11.9 2.4 9.4 7.4 2.6 1 1 1 2 2 2 0 Protein SOGA DUF4094 PF13334.6 EPE32885.1 - 2.9 8.4 7.5 0.47 10.9 1.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) DUF3987 PF13148.6 EPE32885.1 - 2.9 6.8 13.8 0.94 8.4 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) HAUS6_N PF14661.6 EPE32885.1 - 3 7.4 16.4 0.79 9.3 4.1 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus ZapB PF06005.12 EPE32885.1 - 3.6 8.1 21.8 1.2 9.6 5.0 3.2 2 1 1 3 3 3 0 Cell division protein ZapB bZIP_2 PF07716.15 EPE32885.1 - 3.6 7.8 15.4 2.1 8.5 0.6 3.4 3 2 0 3 3 2 0 Basic region leucine zipper Csm1_N PF18504.1 EPE32885.1 - 4.1 7.8 17.0 0.41 11.0 2.3 3.5 1 1 2 3 3 3 0 Csm1 N-terminal domain Fmp27_WPPW PF10359.9 EPE32885.1 - 4.1 6.1 15.6 3.4 6.4 5.3 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF1003 PF06210.11 EPE32885.1 - 4.5 7.4 7.8 11 6.1 0.5 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1003) V_ATPase_I PF01496.19 EPE32885.1 - 4.6 5.0 13.3 7.2 4.4 12.1 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1192 PF06698.11 EPE32885.1 - 4.6 7.4 13.2 0.1 12.7 2.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) DUF724 PF05266.14 EPE32885.1 - 4.9 6.9 18.0 6.5 6.5 7.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF2968 PF11180.8 EPE32885.1 - 5.3 6.6 17.4 2.5 7.7 3.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DivIC PF04977.15 EPE32885.1 - 5.4 6.9 23.4 0.63 9.8 5.5 3.6 1 1 2 4 4 4 0 Septum formation initiator GrpE PF01025.19 EPE32885.1 - 6 6.5 22.0 1.8e+04 -6.1 22.0 2.8 1 1 0 1 1 0 0 GrpE bZIP_Maf PF03131.17 EPE32885.1 - 6.6 7.3 10.3 1.2 9.6 1.5 2.5 1 1 0 2 2 2 0 bZIP Maf transcription factor Med9 PF07544.13 EPE32885.1 - 7 6.8 11.2 3.4 7.8 0.6 3.0 1 1 3 4 4 3 0 RNA polymerase II transcription mediator complex subunit 9 HemX PF04375.14 EPE32885.1 - 8.1 5.6 17.6 3.9 6.7 5.8 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DASH_Spc34 PF08657.10 EPE32885.1 - 8.5 6.1 15.1 0.97 9.2 5.7 2.2 1 1 1 2 2 2 0 DASH complex subunit Spc34 Nop25 PF09805.9 EPE32886.1 - 6.8e-38 130.2 12.8 6.8e-38 130.2 12.8 2.2 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) DUF1043 PF06295.12 EPE32886.1 - 0.062 13.3 5.0 0.16 12.0 5.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Tho2 PF11262.8 EPE32886.1 - 0.37 10.0 4.0 0.69 9.1 4.0 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4661 PF15576.6 EPE32886.1 - 1.4 8.8 5.2 5.5 6.8 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) ATP-synt_S1 PF05827.12 EPE32887.1 - 8.1e-06 25.7 0.1 1.9e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Fcf1 PF04900.12 EPE32888.1 - 1e-33 115.7 0.1 1.9e-33 114.8 0.1 1.5 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EPE32888.1 - 4e-13 49.7 0.1 1.1e-12 48.3 0.0 1.7 2 0 0 2 2 2 1 PIN like domain DUF4200 PF13863.6 EPE32888.1 - 0.012 16.0 4.4 0.012 16.0 4.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Podoplanin PF05808.11 EPE32890.1 - 0.0091 16.1 9.4 0.02 15.0 9.4 1.5 1 0 0 1 1 1 1 Podoplanin Plasmodium_Vir PF05795.11 EPE32890.1 - 0.01 15.3 1.5 0.013 15.0 1.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Gram_pos_anchor PF00746.21 EPE32890.1 - 0.027 14.4 0.9 0.027 14.4 0.9 2.3 2 0 0 2 2 2 0 LPXTG cell wall anchor motif RIFIN PF02009.16 EPE32890.1 - 0.062 13.2 0.3 0.089 12.7 0.3 1.1 1 0 0 1 1 1 0 Rifin Apt1 PF10351.9 EPE32890.1 - 0.2 10.4 6.2 0.25 10.2 6.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FixQ PF05545.11 EPE32890.1 - 0.21 11.6 0.1 0.37 10.8 0.1 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Macoilin PF09726.9 EPE32890.1 - 0.37 9.3 10.0 0.48 8.9 10.0 1.1 1 0 0 1 1 1 0 Macoilin family FAM199X PF15814.5 EPE32890.1 - 1 8.4 14.9 1.6 7.8 14.9 1.3 1 0 0 1 1 1 0 Protein family FAM199X TMEM154 PF15102.6 EPE32890.1 - 1.4 8.8 6.8 5.5 6.9 6.8 2.0 1 1 0 1 1 1 0 TMEM154 protein family PI3K_1B_p101 PF10486.9 EPE32890.1 - 1.5 6.5 5.8 1.9 6.2 5.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SSP160 PF06933.11 EPE32890.1 - 2.5 6.2 25.3 5.1 5.2 25.3 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Miga PF10265.9 EPE32890.1 - 3.3 6.6 14.8 3.1 6.7 0.0 2.0 1 1 1 2 2 2 0 Mitoguardin Dynamin_M PF01031.20 EPE32891.1 - 4.9e-23 81.7 0.0 2.6e-20 72.8 0.0 2.3 1 1 0 1 1 1 1 Dynamin central region GED PF02212.18 EPE32891.1 - 0.029 14.5 0.0 0.089 13.0 0.0 1.8 1 0 0 1 1 1 0 Dynamin GTPase effector domain DUF2267 PF10025.9 EPE32891.1 - 0.062 13.6 0.1 0.35 11.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Dynamin_N PF00350.23 EPE32892.1 - 5.4e-25 88.4 0.0 1.1e-24 87.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EPE32892.1 - 3.7e-06 27.0 0.5 3.9e-05 23.7 0.1 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EPE32892.1 - 0.013 15.2 0.4 0.034 13.9 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 EPE32892.1 - 0.029 14.2 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EPE32892.1 - 0.041 14.4 0.1 0.12 12.9 0.0 1.9 1 1 1 2 2 2 0 ABC transporter FeoB_N PF02421.18 EPE32892.1 - 0.043 13.3 0.1 8.2 5.9 0.0 2.7 2 1 1 3 3 3 0 Ferrous iron transport protein B AAA_16 PF13191.6 EPE32892.1 - 0.069 13.5 0.0 0.097 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EPE32892.1 - 0.075 12.4 0.0 1.4 8.3 0.0 2.2 2 1 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 EPE32892.1 - 0.075 12.8 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Roc PF08477.13 EPE32892.1 - 0.082 13.1 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF4280 PF14107.6 EPE32893.1 - 0.049 14.4 0.4 0.091 13.6 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4280) Trefoil PF00088.18 EPE32893.1 - 0.095 12.6 2.5 0.2 11.6 2.5 1.5 1 0 0 1 1 1 0 Trefoil (P-type) domain DUF736 PF05284.12 EPE32893.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF736) Peptidase_M19 PF01244.21 EPE32894.1 - 1e-84 284.4 0.0 1.3e-84 284.1 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 EPE32894.1 - 0.01 15.7 0.0 0.014 15.2 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase DUF2938 PF11158.8 EPE32895.1 - 0.013 15.0 0.1 0.013 15.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) PqiA PF04403.13 EPE32895.1 - 0.049 13.5 2.0 0.052 13.4 2.0 1.0 1 0 0 1 1 1 0 Paraquat-inducible protein A RhoGAP PF00620.27 EPE32896.1 - 3.7e-17 62.5 0.4 7.9e-17 61.5 0.1 1.8 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 EPE32896.1 - 5.8e-11 42.3 0.0 1.4e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 EPE32896.1 - 5.1e-09 36.3 0.0 1.5e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain N-SET PF11764.8 EPE32897.1 - 2.1e-53 181.0 0.7 2.1e-53 181.0 0.7 2.2 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 EPE32897.1 - 2.4e-22 78.3 0.7 7.3e-22 76.8 0.1 2.2 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated SET PF00856.28 EPE32897.1 - 7.9e-20 71.9 0.3 7.9e-20 71.9 0.3 3.5 2 1 0 2 2 2 1 SET domain AAA PF00004.29 EPE32899.1 - 1e-37 129.5 0.0 2.9e-14 53.6 0.0 3.8 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 EPE32899.1 - 2e-15 56.7 0.7 4.4e-08 33.2 0.0 3.8 3 0 0 3 3 3 2 AAA lid domain AAA_22 PF13401.6 EPE32899.1 - 1.4e-11 44.8 2.5 0.086 13.1 0.1 6.1 4 2 0 4 4 4 3 AAA domain AAA_30 PF13604.6 EPE32899.1 - 1.7e-10 40.9 0.0 0.0011 18.8 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 EPE32899.1 - 3.1e-07 30.5 0.0 0.004 17.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EPE32899.1 - 5.8e-07 29.4 0.1 0.092 12.5 0.0 3.9 4 2 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 EPE32899.1 - 6.7e-07 28.9 0.1 0.47 9.8 0.0 5.2 5 1 1 6 6 6 1 Bacterial TniB protein RNA_helicase PF00910.22 EPE32899.1 - 1.2e-06 28.9 0.2 0.68 10.3 0.0 4.6 5 0 0 5 5 5 2 RNA helicase AAA_19 PF13245.6 EPE32899.1 - 3e-06 27.6 0.1 0.66 10.3 0.0 4.4 3 1 1 4 4 4 2 AAA domain AAA_24 PF13479.6 EPE32899.1 - 4.2e-06 26.6 0.0 0.15 11.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EPE32899.1 - 1.2e-05 25.9 0.1 0.46 11.0 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EPE32899.1 - 1.2e-05 25.7 0.0 0.59 10.5 0.0 4.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 EPE32899.1 - 2.1e-05 24.7 0.1 0.33 11.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 EPE32899.1 - 3.2e-05 23.4 0.0 0.33 10.3 0.0 3.0 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EPE32899.1 - 8.3e-05 22.9 0.1 0.1 12.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 EPE32899.1 - 0.00081 19.8 0.2 3.3 8.1 0.0 3.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EPE32899.1 - 0.0013 18.5 0.4 1.5 8.5 0.0 2.9 3 0 0 3 3 2 2 Viral (Superfamily 1) RNA helicase Torsin PF06309.11 EPE32899.1 - 0.0027 17.8 0.0 0.43 10.7 0.0 3.0 3 0 0 3 3 3 1 Torsin AAA_29 PF13555.6 EPE32899.1 - 0.003 17.3 0.0 21 4.9 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EPE32899.1 - 0.0038 16.8 0.1 8.3 5.9 0.0 3.4 3 0 0 3 3 3 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EPE32899.1 - 0.011 15.5 0.0 10 5.8 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein NTPase_1 PF03266.15 EPE32899.1 - 0.012 15.5 0.2 2.9 7.8 0.0 2.7 2 0 0 2 2 2 0 NTPase Zot PF05707.12 EPE32899.1 - 0.016 14.9 0.1 1.8 8.2 0.0 3.4 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) SRP54 PF00448.22 EPE32899.1 - 0.02 14.5 0.4 1.4 8.6 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Asp PF00026.23 EPE32901.1 - 3e-09 36.8 0.0 4.4e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease HicA_toxin PF07927.12 EPE32902.1 - 5.5e-07 29.5 1.3 1.3e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 HicA toxin of bacterial toxin-antitoxin, DUF4802 PF16060.5 EPE32902.1 - 0.008 16.3 0.1 0.018 15.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4802) DUF4188 PF13826.6 EPE32903.1 - 3.1e-25 88.8 0.1 4.1e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 EPE32903.1 - 0.0094 15.4 0.6 0.55 9.6 0.1 2.0 1 1 1 2 2 2 2 Haem-containing dehydratase Adenylsucc_synt PF00709.21 EPE32904.1 - 5.1e-169 562.6 0.0 5.8e-169 562.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase KHA PF11834.8 EPE32904.1 - 0.072 13.2 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel Fungal_trans PF04082.18 EPE32905.1 - 8.5e-10 38.1 0.1 2.7e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE32905.1 - 0.045 13.9 4.3 0.093 12.9 4.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TSC21 PF15217.6 EPE32905.1 - 0.099 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 TSC21 family PRIMA1 PF16101.5 EPE32905.1 - 0.42 10.7 3.8 0.97 9.5 3.8 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-met PF12874.7 EPE32906.1 - 8e-06 26.1 1.5 0.077 13.4 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EPE32906.1 - 1.1e-05 25.6 1.0 0.012 15.9 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EPE32906.1 - 0.0066 17.2 5.2 2.1 9.4 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger AKAP95 PF04988.12 EPE32906.1 - 0.0092 16.2 0.1 1.7 8.9 0.1 2.3 2 0 0 2 2 2 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_2 PF12756.7 EPE32906.1 - 0.0097 16.2 1.0 0.71 10.2 0.2 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 EPE32906.1 - 0.055 13.9 1.6 0.14 12.6 1.6 1.6 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2 PF00096.26 EPE32906.1 - 0.062 13.8 3.7 0.96 10.0 0.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 EPE32906.1 - 0.18 11.5 0.1 0.48 10.1 0.1 1.8 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_PR_Knuckle PF18445.1 EPE32906.1 - 0.22 11.3 1.4 19 5.1 0.1 2.5 2 0 0 2 2 2 0 PR zinc knuckle motif zf-Di19 PF05605.12 EPE32906.1 - 0.25 11.7 0.9 49 4.3 0.0 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 EPE32906.1 - 0.47 10.3 1.7 27 4.6 0.3 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type DEAD PF00270.29 EPE32907.1 - 5.4e-49 166.3 0.0 1.2e-48 165.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE32907.1 - 1.2e-12 48.2 0.0 3.5e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE32907.1 - 0.0044 17.0 0.0 0.008 16.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EPE32907.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Proteasome PF00227.26 EPE32908.1 - 4.2e-36 124.2 0.0 4.8e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.32 EPE32909.1 - 7.8e-20 70.8 2.3 1.1e-05 26.1 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF885 PF05960.11 EPE32909.1 - 0.024 14.3 0.4 0.032 13.9 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Nup160 PF11715.8 EPE32909.1 - 0.074 11.7 0.3 18 3.8 0.0 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Histone_HNS PF00816.21 EPE32909.1 - 0.49 11.2 4.6 0.25 12.2 0.6 2.5 2 0 0 2 2 2 0 H-NS histone family UCH PF00443.29 EPE32910.1 - 1.2e-26 93.8 0.0 1.8e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EPE32910.1 - 3e-11 43.5 0.3 6e-11 42.5 0.3 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EPE32910.1 - 0.0024 17.5 0.0 0.012 15.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1064 PF06356.11 EPE32910.1 - 0.17 12.2 0.4 0.52 10.7 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) DUF2070 PF09843.9 EPE32911.1 - 6.1 5.0 12.4 8.5 4.5 12.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AA_permease_2 PF13520.6 EPE32912.1 - 3.3e-55 187.6 56.6 4.2e-55 187.3 56.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE32912.1 - 6.5e-18 64.6 49.0 9.3e-18 64.1 49.0 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short_C2 PF13561.6 EPE32913.1 - 5e-42 144.0 0.0 6.3e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE32913.1 - 8e-39 133.1 0.0 9.3e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE32913.1 - 1.9e-10 41.0 0.2 3.6e-10 40.0 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE32913.1 - 0.0038 16.7 0.0 0.09 12.2 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EPE32913.1 - 0.03 13.5 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Phage_sheath_1 PF04984.14 EPE32913.1 - 0.14 12.0 0.4 0.78 9.6 0.0 2.0 2 0 0 2 2 2 0 Phage tail sheath protein subtilisin-like domain Oxidored_FMN PF00724.20 EPE32914.1 - 3.6e-88 296.1 0.0 4.2e-88 295.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family nsp9 PF08710.10 EPE32914.1 - 0.061 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 nsp9 replicase AP_endonuc_2 PF01261.24 EPE32914.1 - 0.079 12.4 0.0 7 6.0 0.0 2.4 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel NAD_binding_10 PF13460.6 EPE32915.1 - 3.1e-07 30.4 0.0 8.3e-06 25.8 0.0 2.5 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPE32915.1 - 8.3e-06 25.5 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Methyltransf_33 PF10017.9 EPE32916.1 - 1.5e-79 267.4 0.0 1.7e-79 267.2 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FAD_binding_4 PF01565.23 EPE32917.1 - 1.4e-16 60.5 0.5 2.6e-16 59.6 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE32917.1 - 4.2e-11 42.8 0.2 9.8e-11 41.6 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like Trp_DMAT PF11991.8 EPE32918.1 - 3.6e-112 375.4 0.1 4.4e-112 375.1 0.1 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Catalase PF00199.19 EPE32919.1 - 7.8e-121 403.8 0.0 1.1e-120 403.3 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EPE32919.1 - 0.0088 16.2 0.0 0.023 14.9 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive Replic_Relax PF13814.6 EPE32919.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Replication-relaxation HAD PF12710.7 EPE32920.1 - 7.9e-24 85.1 0.0 1.1e-23 84.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EPE32920.1 - 0.0027 17.2 0.0 0.35 10.2 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase UMPH-1 PF05822.12 EPE32920.1 - 0.036 13.6 0.0 0.069 12.6 0.0 1.5 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 EPE32920.1 - 0.14 12.4 0.9 7 6.9 0.0 2.9 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase HET PF06985.11 EPE32921.1 - 1.5e-35 122.7 0.5 2.9e-35 121.8 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CDP-OH_P_transf PF01066.21 EPE32922.1 - 1e-12 48.6 0.3 1e-12 48.6 0.3 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PcfK PF14058.6 EPE32923.1 - 0.072 13.4 0.3 0.072 13.4 0.3 1.9 2 0 0 2 2 2 0 PcfK-like protein HSP70 PF00012.20 EPE32926.1 - 7.4e-172 572.7 8.0 7.4e-172 572.7 8.0 2.2 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EPE32926.1 - 2.2e-13 49.7 0.1 5.8e-12 45.1 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EPE32926.1 - 0.025 15.0 2.4 1.4 9.4 0.1 3.3 2 2 0 2 2 2 0 Cell division protein FtsA HSP70 PF00012.20 EPE32927.1 - 2.4e-257 855.0 6.4 2.7e-257 854.8 6.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EPE32927.1 - 1.2e-17 63.8 0.1 3.3e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EPE32927.1 - 0.002 17.9 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EPE32927.1 - 0.022 14.0 0.1 0.049 12.9 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase FtsA PF14450.6 EPE32927.1 - 0.038 14.4 4.2 8.4 6.9 0.2 3.4 3 2 0 3 3 3 0 Cell division protein FtsA StbA PF06406.11 EPE32927.1 - 0.041 13.1 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 StbA protein TcpS PF17456.2 EPE32927.1 - 0.043 13.9 0.7 11 6.0 0.2 2.3 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S MutS_III PF05192.18 EPE32927.1 - 2.4 8.3 5.0 8.3 6.6 0.8 2.5 2 1 0 2 2 2 0 MutS domain III OMPdecase PF00215.24 EPE32928.1 - 9.5e-93 309.9 0.0 1.1e-92 309.7 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Spt20 PF12090.8 EPE32930.1 - 4.1e-47 160.7 0.0 4.1e-47 160.7 0.0 7.3 2 1 1 3 3 3 1 Spt20 family DUF3128 PF11326.8 EPE32931.1 - 3.5e-24 85.0 2.0 5.9e-24 84.2 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Pox_A_type_inc PF04508.12 EPE32931.1 - 0.0057 16.5 3.0 0.014 15.2 3.0 1.7 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat PRCC PF10253.9 EPE32931.1 - 0.011 16.6 2.1 0.012 16.4 2.1 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting RNA12 PF10443.9 EPE32932.1 - 1.6e-171 570.9 0.1 2.1e-171 570.6 0.1 1.1 1 0 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 EPE32932.1 - 6.2e-05 23.0 0.1 0.00024 21.1 0.1 2.0 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 EPE32932.1 - 0.0027 17.5 0.0 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.9 EPE32932.1 - 0.0085 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) AAA_16 PF13191.6 EPE32932.1 - 0.055 13.8 0.3 1.3 9.4 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain ScsC_N PF18312.1 EPE32932.1 - 0.07 13.0 0.7 0.35 10.7 0.1 2.4 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain BRK PF07533.16 EPE32932.1 - 0.26 11.0 0.8 8.8 6.0 0.1 3.1 3 0 0 3 3 3 0 BRK domain FBPase PF00316.20 EPE32933.1 - 4.4e-71 238.3 0.1 5.6e-71 237.9 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain CwfJ_C_1 PF04677.15 EPE32934.1 - 8.5e-32 109.6 0.0 1.4e-31 108.9 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EPE32934.1 - 5.7e-29 100.9 0.3 5.7e-29 100.9 0.3 2.4 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 FumaraseC_C PF10415.9 EPE32934.1 - 0.077 13.4 0.3 20 5.7 0.0 2.9 2 0 0 2 2 2 0 Fumarase C C-terminus Dsh_C PF12316.8 EPE32934.1 - 3.4 8.0 9.9 12 6.2 9.9 1.8 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Presenilin PF01080.17 EPE32934.1 - 9.3 4.9 13.7 16 4.1 13.7 1.3 1 0 0 1 1 1 0 Presenilin ATP_bind_1 PF03029.17 EPE32935.1 - 1.2e-71 241.3 0.0 1.7e-71 240.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EPE32935.1 - 1.4e-05 24.8 0.0 0.0012 18.4 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EPE32935.1 - 0.00013 21.0 0.0 0.038 13.0 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 EPE32935.1 - 0.00029 20.6 0.0 0.0039 16.9 0.0 2.2 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 EPE32935.1 - 0.00031 20.5 0.0 0.00075 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EPE32935.1 - 0.0012 18.1 0.0 0.005 16.1 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain G-alpha PF00503.20 EPE32935.1 - 0.0018 17.5 0.0 0.077 12.1 0.0 2.5 3 0 0 3 3 3 1 G-protein alpha subunit MMR_HSR1 PF01926.23 EPE32935.1 - 0.0031 17.6 0.0 0.03 14.4 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EPE32935.1 - 0.0034 17.6 0.0 0.0086 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPE32935.1 - 0.0039 17.6 0.0 0.0096 16.3 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EPE32935.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain FeoB_N PF02421.18 EPE32935.1 - 0.005 16.4 0.1 0.13 11.8 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EPE32935.1 - 0.0077 16.1 0.1 3.8 7.4 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase SRP54 PF00448.22 EPE32935.1 - 0.0082 15.8 0.0 0.042 13.5 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EPE32935.1 - 0.0086 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EPE32935.1 - 0.0088 16.3 0.0 0.043 14.1 0.0 2.2 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 EPE32935.1 - 0.011 15.0 0.0 0.029 13.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Arf PF00025.21 EPE32935.1 - 0.012 15.1 0.0 1.3 8.5 0.0 2.9 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_7 PF12775.7 EPE32935.1 - 0.015 14.8 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 EPE32935.1 - 0.017 14.7 0.1 0.27 10.8 0.1 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 EPE32935.1 - 0.018 14.3 0.0 0.067 12.4 0.0 1.8 1 1 0 1 1 1 0 KAP family P-loop domain IlvC PF01450.19 EPE32935.1 - 0.02 15.2 0.7 0.87 9.9 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Roc PF08477.13 EPE32935.1 - 0.022 15.0 0.0 2.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase 6PF2K PF01591.18 EPE32935.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PduV-EutP PF10662.9 EPE32935.1 - 0.15 11.8 0.2 1.2 8.9 0.0 2.4 3 1 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation A_deaminase PF00962.22 EPE32936.1 - 7.4e-80 268.7 0.0 8.4e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 EPE32936.1 - 0.00012 21.6 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family HET PF06985.11 EPE32937.1 - 2.1e-37 128.7 2.0 3.6e-37 127.9 2.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3828 PF12883.7 EPE32937.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3828) SBP_bac_3 PF00497.20 EPE32937.1 - 0.13 11.6 0.0 0.47 9.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 Fungal_trans PF04082.18 EPE32938.1 - 2.1e-24 86.0 0.1 4e-24 85.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE32938.1 - 0.00029 20.9 13.9 0.00029 20.9 13.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 EPE32939.1 - 5.3e-14 52.5 0.0 7.2e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE32939.1 - 2.3e-10 40.3 0.0 3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EPE32939.1 - 4.6e-05 22.6 0.0 5.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EPE32939.1 - 0.00035 20.1 0.0 0.00045 19.7 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EPE32939.1 - 0.00064 19.3 0.2 0.00094 18.8 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 EPE32939.1 - 0.0011 19.2 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EPE32939.1 - 0.0013 18.9 0.1 0.0024 18.1 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain PCP PF02429.15 EPE32939.1 - 0.0082 16.5 0.1 0.012 15.9 0.1 1.2 1 0 0 1 1 1 1 Peridinin-chlorophyll A binding protein Semialdhyde_dh PF01118.24 EPE32939.1 - 0.011 16.1 0.1 0.016 15.7 0.1 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 EPE32940.1 - 2.1e-06 26.9 3.1 0.028 13.3 0.1 2.9 3 1 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EPE32940.1 - 0.0021 18.1 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Presenilin PF01080.17 EPE32940.1 - 0.17 10.6 0.3 0.24 10.1 0.3 1.1 1 0 0 1 1 1 0 Presenilin DUF4682 PF15733.5 EPE32940.1 - 0.59 10.7 4.3 76 3.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4682) SprA-related PF12118.8 EPE32940.1 - 0.68 9.0 7.6 1.3 8.1 7.6 1.3 1 0 0 1 1 1 0 SprA-related family Macoilin PF09726.9 EPE32940.1 - 2 6.8 7.4 2.8 6.4 7.4 1.1 1 0 0 1 1 1 0 Macoilin family Aldo_ket_red PF00248.21 EPE32941.1 - 1.3e-62 211.6 0.0 1.6e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pro_CA PF00484.19 EPE32942.1 - 4.8e-45 153.6 0.0 5.9e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Ribosomal_L7Ae PF01248.26 EPE32943.1 - 4.7e-21 74.3 0.9 7.9e-21 73.6 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 EPE32943.1 - 0.14 11.1 0.2 0.18 10.8 0.2 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) zn-ribbon_14 PF16503.5 EPE32944.1 - 1.3e-18 66.2 3.7 1.3e-18 66.2 3.7 3.4 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 EPE32944.1 - 2.9e-18 66.3 0.0 4.7e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 EPE32944.1 - 0.016 14.7 0.6 0.016 14.7 0.6 3.2 4 0 0 4 4 4 0 RecR protein tRNA_Me_trans PF03054.16 EPE32944.1 - 0.043 12.6 0.0 0.08 11.7 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.20 EPE32944.1 - 0.069 13.3 6.5 0.57 10.4 0.5 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) RNHCP PF12647.7 EPE32944.1 - 1.1 9.3 6.8 1.3 9.0 0.1 2.7 3 0 0 3 3 3 0 RNHCP domain GATase PF00117.28 EPE32947.1 - 3.4e-07 30.2 0.0 4.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Cu_amine_oxid PF01179.20 EPE32948.1 - 5.5e-161 536.1 0.1 6.6e-161 535.8 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 EPE32948.1 - 5.5e-06 26.5 0.2 1.6e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 EPE32948.1 - 2.8e-05 24.5 0.0 9.2e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Utp8 PF10395.9 EPE32949.1 - 3.6e-08 32.4 0.1 9e-07 27.8 0.1 2.8 3 1 0 3 3 3 1 Utp8 family Rad17 PF03215.15 EPE32950.1 - 3e-09 37.1 0.1 0.0014 18.6 0.0 3.4 3 0 0 3 3 3 2 Rad17 P-loop domain AAA PF00004.29 EPE32950.1 - 2.5e-07 31.2 1.6 2.5e-06 28.0 1.6 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPE32950.1 - 0.0027 18.0 0.1 0.023 15.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPE32950.1 - 0.013 15.9 0.1 0.033 14.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EPE32950.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EPE32950.1 - 0.079 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 EPE32950.1 - 0.11 13.1 0.0 0.41 11.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EPE32950.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 EPE32950.1 - 0.12 12.3 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EPE32950.1 - 0.17 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Catalase PF00199.19 EPE32951.1 - 5.8e-182 605.0 0.4 6.8e-182 604.8 0.4 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EPE32951.1 - 6.1e-10 39.2 0.2 1.4e-09 38.0 0.2 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive bZIP_1 PF00170.21 EPE32952.1 - 2.3e-11 43.6 9.0 3.7e-11 42.9 9.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPE32952.1 - 7.2e-06 26.0 11.9 7.2e-06 26.0 11.9 1.5 2 0 0 2 2 2 1 Basic region leucine zipper PARM PF17061.5 EPE32952.1 - 0.0038 17.4 2.3 0.0046 17.1 2.3 1.1 1 0 0 1 1 1 1 PARM TMCO5 PF14992.6 EPE32952.1 - 0.049 13.2 1.5 0.077 12.6 1.5 1.2 1 0 0 1 1 1 0 TMCO5 family DUF1465 PF07323.12 EPE32952.1 - 0.059 13.2 1.0 0.12 12.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) SDA1 PF05285.12 EPE32953.1 - 1.1e-97 327.6 37.8 1.1e-97 327.6 37.8 2.3 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 EPE32953.1 - 9.4e-22 77.1 0.8 2.4e-21 75.8 0.0 2.2 2 0 0 2 2 2 1 NUC130/3NT domain AA_permease_2 PF13520.6 EPE32956.1 - 8e-45 153.4 51.3 5.1e-44 150.8 51.3 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE32956.1 - 6.8e-24 84.3 47.7 2.8e-23 82.2 47.7 1.9 1 1 0 1 1 1 1 Amino acid permease SGL PF08450.12 EPE32957.1 - 0.0026 17.4 0.0 0.016 14.8 0.1 2.1 3 0 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region ADH_zinc_N PF00107.26 EPE32958.1 - 1.3e-11 44.6 0.0 2.2e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE32958.1 - 2.5e-06 27.4 0.0 4.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fimbrial_K88 PF02432.15 EPE32958.1 - 0.0033 17.4 0.3 0.0033 17.4 0.3 1.7 2 0 0 2 2 2 1 Fimbrial, major and minor subunit ADH_N_2 PF16884.5 EPE32958.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase WD40 PF00400.32 EPE32961.1 - 3.8e-48 160.5 23.0 5.2e-07 30.3 0.1 8.3 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 EPE32961.1 - 9.8e-13 47.6 1.7 4.6e-12 45.5 0.4 2.3 1 1 1 2 2 2 1 F-box domain F-box-like PF12937.7 EPE32961.1 - 3.2e-12 46.2 0.4 6.5e-12 45.2 0.4 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 EPE32961.1 - 1.1e-11 44.1 6.2 0.11 11.1 0.0 5.8 4 1 2 6 6 6 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EPE32961.1 - 4.5e-07 30.1 0.6 0.32 11.3 0.0 5.3 2 2 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 EPE32961.1 - 0.0017 18.3 0.2 0.006 16.5 0.1 2.1 2 0 0 2 2 2 1 F-box Nucleoporin_N PF08801.11 EPE32961.1 - 0.043 12.6 0.4 1.6 7.3 0.1 3.0 3 1 0 3 3 3 0 Nup133 N terminal like Fungal_trans_2 PF11951.8 EPE32962.1 - 1.7e-05 23.8 0.1 3e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.26 EPE32963.1 - 7.9e-24 84.1 0.2 2.2e-23 82.7 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE32963.1 - 1.8e-15 58.2 0.0 4.8e-15 56.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE32963.1 - 6.7e-05 22.7 0.0 0.00024 20.9 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 EPE32963.1 - 0.0018 18.0 0.2 0.0029 17.3 0.2 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DAGK_cat PF00781.24 EPE32963.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain APG17 PF04108.12 EPE32964.1 - 1.1e-132 443.0 4.6 1.3e-132 442.7 4.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF4110 PF13422.6 EPE32964.1 - 0.018 15.1 0.2 0.075 13.1 0.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) FlgN PF05130.12 EPE32964.1 - 0.094 13.2 2.3 12 6.4 0.0 2.9 3 0 0 3 3 3 0 FlgN protein Minor_capsid_3 PF12691.7 EPE32964.1 - 0.2 12.0 1.9 13 6.2 0.1 3.2 3 0 0 3 3 3 0 Minor capsid protein from bacteriophage Sec5 PF15469.6 EPE32964.1 - 1.4 8.7 10.2 7 6.4 0.2 4.3 4 1 1 5 5 5 0 Exocyst complex component Sec5 LMBR1 PF04791.16 EPE32964.1 - 6.4 5.6 5.2 1.4 7.8 1.4 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein SF-assemblin PF06705.11 EPE32964.1 - 6.7 6.0 15.1 0.21 10.9 1.3 3.4 2 2 0 3 3 3 0 SF-assemblin/beta giardin Exo_endo_phos PF03372.23 EPE32967.1 - 2.4e-09 37.0 0.1 3.9e-09 36.4 0.1 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EPE32967.1 - 0.024 14.5 0.0 0.26 11.1 0.0 2.2 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Fungal_trans PF04082.18 EPE32968.1 - 2.7e-06 26.6 0.2 5.6e-06 25.6 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Serglycin PF04360.12 EPE32968.1 - 0.48 10.4 4.1 1 9.3 4.1 1.5 1 0 0 1 1 1 0 Serglycin Tyrosinase PF00264.20 EPE32969.1 - 4.1e-48 164.6 1.4 6.2e-48 164.0 1.4 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EPE32969.1 - 0.023 15.4 0.0 0.041 14.6 0.0 1.4 1 0 0 1 1 1 0 Tyosinase C-terminal domain Peptidase_M16_M PF16187.5 EPE32970.1 - 8.7e-97 323.8 0.1 1.5e-96 323.0 0.1 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EPE32970.1 - 1.9e-32 112.3 0.7 1.9e-32 112.3 0.7 2.2 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EPE32970.1 - 1.4e-30 106.6 0.0 1.5e-16 60.9 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain TIP41 PF04176.13 EPE32972.1 - 3.6e-68 228.4 0.2 4.5e-68 228.1 0.2 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.25 EPE32973.1 - 6.3e-71 238.8 0.0 8.1e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE32973.1 - 7.3e-42 143.4 0.0 9.9e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE32973.1 - 1.5e-07 31.1 0.0 5.1e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EPE32973.1 - 0.0055 16.1 0.1 0.01 15.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EPE32973.1 - 0.023 14.2 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 EPE32973.1 - 0.052 12.5 0.0 0.052 12.5 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain FTA2 PF13095.6 EPE32973.1 - 0.058 13.0 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EPE32973.1 - 0.08 12.5 0.0 0.24 11.0 0.0 1.8 1 1 1 2 2 2 0 RIO1 family Peptidase_M76 PF09768.9 EPE32974.1 - 4.9e-71 238.0 3.8 5.9e-71 237.7 3.8 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 EPE32974.1 - 0.0042 16.9 0.9 0.0042 16.9 0.9 2.0 1 1 1 2 2 2 1 SprT-like family Peptidase_M91 PF14891.6 EPE32974.1 - 0.0055 17.1 0.0 0.0085 16.4 0.0 1.3 1 0 0 1 1 1 1 Effector protein Tox-MPTase2 PF15638.6 EPE32974.1 - 0.071 12.8 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 AA_kinase PF00696.28 EPE32975.1 - 8.6e-40 136.8 1.7 1.2e-39 136.4 1.7 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EPE32975.1 - 7.7e-14 51.4 1.7 1.6e-13 50.4 0.2 2.2 2 0 0 2 2 2 1 PUA domain Pkinase PF00069.25 EPE32977.1 - 3.1e-33 115.2 0.0 4.9e-32 111.3 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE32977.1 - 9.4e-18 64.4 0.1 3.9e-07 29.6 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase LANC_like PF05147.13 EPE32977.1 - 0.14 10.7 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Lipase_3 PF01764.25 EPE32979.1 - 4e-20 72.1 0.0 6.2e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EPE32979.1 - 0.0099 16.5 0.1 0.015 15.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family APH PF01636.23 EPE32980.1 - 6.1e-10 39.4 0.0 2.8e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EPE32980.1 - 0.00041 19.3 0.0 0.00061 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 EPE32980.1 - 0.0047 16.3 0.0 0.0072 15.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 EPE32980.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase peroxidase PF00141.23 EPE32983.1 - 2.9e-44 151.5 0.0 4e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4064 PF13273.6 EPE32984.1 - 0.76 10.1 3.5 1 9.7 2.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Pkinase PF00069.25 EPE32985.1 - 8.2e-30 104.0 0.0 5.6e-17 62.0 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EPE32985.1 - 1.1e-17 64.2 0.0 2.4e-15 56.5 0.0 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase CBM_21 PF03370.13 EPE32986.1 - 4.4e-29 100.9 0.2 1.2e-28 99.5 0.2 1.8 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EPE32986.1 - 1.6e-08 35.0 0.8 3.4e-08 34.0 0.8 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) DUF1441 PF07278.11 EPE32986.1 - 0.026 14.4 1.1 0.059 13.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1441) RPW8 PF05659.11 EPE32986.1 - 0.028 14.1 3.9 0.045 13.5 0.2 2.7 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 RecG_N PF17190.4 EPE32986.1 - 0.24 12.1 0.2 0.24 12.1 0.2 2.8 3 0 0 3 3 3 0 RecG N-terminal helical domain UPF0242 PF06785.11 EPE32986.1 - 2.4 8.2 12.8 3.4 7.7 4.3 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF948 PF06103.11 EPE32986.1 - 2.6 8.4 10.1 12 6.3 0.2 4.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Peptidase_S46 PF10459.9 EPE32986.1 - 3.1 6.3 7.9 0.19 10.3 0.9 1.9 2 0 0 2 2 2 0 Peptidase S46 ISG65-75 PF11727.8 EPE32986.1 - 6.5 5.9 12.5 3.1 6.9 4.9 2.4 2 0 0 2 2 2 0 Invariant surface glycoprotein Peptidase_S8 PF00082.22 EPE32989.1 - 3.7e-05 23.2 0.9 3.7e-05 23.2 0.9 2.4 3 1 0 3 3 3 1 Subtilase family UCH PF00443.29 EPE32990.1 - 3.2e-69 233.3 0.0 5.5e-69 232.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EPE32990.1 - 3.1e-12 46.9 0.1 1.4e-11 44.8 0.0 2.2 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 EPE32990.1 - 4.5e-11 42.9 0.0 0.00027 20.6 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase BCS1_N PF08740.11 EPE32991.1 - 1.6e-55 188.0 0.5 1.6e-55 188.0 0.5 1.9 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 EPE32991.1 - 1.1e-17 64.7 0.0 6.8e-16 58.9 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE32991.1 - 0.0027 18.1 0.1 0.013 15.9 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EPE32991.1 - 0.0048 16.7 0.0 0.0085 15.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 EPE32991.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 EPE32991.1 - 0.012 15.6 0.0 0.047 13.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EPE32991.1 - 0.022 14.6 2.3 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EPE32991.1 - 0.056 12.6 0.0 0.15 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 EPE32991.1 - 0.12 12.8 0.2 3 8.3 0.0 2.9 2 1 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 EPE32991.1 - 1.1 9.8 0.0 1.1 9.8 0.0 3.6 4 1 0 4 4 4 0 AAA domain CBM_21 PF03370.13 EPE32993.1 - 1.5e-35 121.7 1.6 2.8e-35 120.9 1.6 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EPE32993.1 - 8.5e-10 39.1 4.0 1.7e-09 38.1 4.0 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) BolA PF01722.18 EPE32994.1 - 9e-11 41.9 0.0 1.5e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 BolA-like protein Epimerase PF01370.21 EPE32995.1 - 2.3e-21 76.4 0.0 3e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE32995.1 - 5.8e-16 58.8 0.0 9.2e-16 58.1 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EPE32995.1 - 1.1e-07 31.1 0.0 1.3e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EPE32995.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 EPE32995.1 - 0.027 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PhetRS_B1 PF18262.1 EPE32995.1 - 0.18 12.0 0.1 3.7 7.8 0.1 2.4 1 1 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain NAD_binding_4 PF07993.12 EPE32995.1 - 0.23 10.6 0.0 6.4 5.9 0.0 2.5 1 1 0 1 1 1 0 Male sterility protein F_bP_aldolase PF01116.20 EPE32996.1 - 2e-75 253.9 0.0 2.2e-75 253.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF1445 PF07286.12 EPE32996.1 - 0.13 12.2 0.0 2 8.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1445) Glyco_hydro_cc PF11790.8 EPE32997.1 - 5.2e-60 203.0 4.7 6.2e-60 202.7 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Velvet PF11754.8 EPE32998.1 - 2.3e-05 24.5 0.0 2.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Velvet factor tRNA-synt_1d PF00750.19 EPE32999.1 - 1.6e-98 329.9 2.9 2.2e-98 329.4 2.9 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EPE32999.1 - 1.1e-28 99.8 0.5 3.4e-28 98.2 0.5 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EPE32999.1 - 3e-09 37.3 0.0 5e-08 33.4 0.0 2.9 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain ART-PolyVal PF18760.1 EPE32999.1 - 0.1 13.7 0.5 0.28 12.2 0.5 1.8 1 0 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins pRN1_helical PF13010.6 EPE32999.1 - 0.16 11.9 0.8 0.89 9.5 0.2 2.2 2 0 0 2 2 2 0 Primase helical domain HSP20 PF00011.21 EPE33000.1 - 2.6e-09 37.2 0.1 1.3e-05 25.3 0.1 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family PIH1_CS PF18201.1 EPE33000.1 - 0.0098 16.3 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain ACC_central PF08326.12 EPE33001.1 - 1.4e-283 942.7 0.0 1.7e-283 942.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EPE33001.1 - 2.7e-188 626.6 0.0 4.5e-188 625.9 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EPE33001.1 - 8.7e-51 172.4 0.0 1.6e-50 171.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EPE33001.1 - 9e-28 97.0 0.1 1.7e-27 96.1 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EPE33001.1 - 1e-21 77.0 0.0 6.3e-20 71.3 0.0 3.1 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EPE33001.1 - 5.1e-17 61.5 0.1 1.3e-16 60.2 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 EPE33001.1 - 0.0068 16.5 0.0 0.026 14.6 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain GxGYxYP_N PF16216.5 EPE33001.1 - 0.016 15.4 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal Dala_Dala_lig_C PF07478.13 EPE33001.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EPE33001.1 - 0.099 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon HET PF06985.11 EPE33002.1 - 3.5e-21 76.1 0.3 8.4e-21 74.9 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) zf-ANAPC11 PF12861.7 EPE33002.1 - 0.09 12.8 3.2 0.19 11.8 3.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MFS_1 PF07690.16 EPE33003.1 - 1.5e-28 99.8 24.3 1.5e-28 99.8 24.3 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily AJAP1_PANP_C PF15298.6 EPE33004.1 - 0.19 11.9 0.2 0.26 11.5 0.2 1.1 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Phage_holin_2_3 PF16080.5 EPE33004.1 - 0.25 11.1 1.1 0.42 10.4 1.1 1.3 1 0 0 1 1 1 0 Bacteriophage holin family HP1 TauD PF02668.16 EPE33005.1 - 1.6e-18 67.5 0.0 2.7e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EPE33005.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 CsiD Zn_clus PF00172.18 EPE33006.1 - 0.0014 18.7 7.7 0.0026 17.9 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.25 EPE33007.1 - 2.3e-06 27.8 0.0 3.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE33007.1 - 5.6e-06 26.3 0.0 8.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE33007.1 - 0.00012 22.4 0.0 0.00034 21.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPE33007.1 - 0.00014 22.0 0.0 0.56 10.3 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPE33007.1 - 0.018 15.2 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 EPE33007.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein HdeA PF06411.11 EPE33007.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 HdeA/HdeB family MOZ_SAS PF01853.18 EPE33007.1 - 0.17 11.5 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family RRM_1 PF00076.22 EPE33009.1 - 7.1e-58 192.4 0.0 4.2e-21 74.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPE33009.1 - 1.5e-07 31.1 0.0 0.0014 18.3 0.0 3.4 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPE33009.1 - 4.7e-07 29.6 0.0 0.063 13.1 0.0 3.9 3 1 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EPE33009.1 - 2.5e-05 24.2 0.2 0.25 11.4 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 EPE33009.1 - 0.00018 21.4 0.0 3.9 7.5 0.0 3.3 2 1 1 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EPE33009.1 - 0.00033 20.7 0.1 0.85 9.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif RRM_8 PF11835.8 EPE33009.1 - 0.00036 20.7 0.0 0.066 13.4 0.0 2.4 2 0 0 2 2 2 1 RRM-like domain Cas_Cas2CT1978 PF09707.10 EPE33009.1 - 0.006 16.6 0.0 3 8.0 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) Limkain-b1 PF11608.8 EPE33009.1 - 0.091 12.9 0.1 31 4.7 0.1 3.5 3 1 0 3 3 3 0 Limkain b1 zf-C2H2_3rep PF18868.1 EPE33010.1 - 0.00037 21.1 1.3 0.00073 20.2 1.2 1.5 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 EPE33010.1 - 0.0037 18.0 18.5 0.12 13.3 1.8 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EPE33010.1 - 0.013 15.7 2.2 0.013 15.7 2.2 1.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 EPE33010.1 - 0.14 12.8 6.7 0.82 10.4 1.0 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 EPE33010.1 - 2.2 8.4 7.6 4.1 7.5 0.5 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger IMUP PF15761.5 EPE33014.1 - 0.046 14.4 4.6 0.077 13.7 4.6 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein MyTH4 PF00784.17 EPE33014.1 - 0.073 13.6 0.1 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 MyTH4 domain DUF445 PF04286.12 EPE33014.1 - 0.1 12.4 0.2 0.97 9.2 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF445) SR-25 PF10500.9 EPE33014.1 - 0.95 9.0 6.6 1.4 8.5 6.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mpv17_PMP22 PF04117.12 EPE33015.1 - 3.3e-11 43.2 3.1 1.9e-10 40.8 2.2 2.2 1 1 1 2 2 2 1 Mpv17 / PMP22 family DUF3557 PF12078.8 EPE33015.1 - 0.00062 19.7 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3557) Phage_holin_T PF11031.8 EPE33015.1 - 0.042 13.3 0.2 0.064 12.7 0.2 1.2 1 0 0 1 1 1 0 Bacteriophage T holin Isochorismatase PF00857.20 EPE33017.1 - 3e-44 151.3 0.0 3.4e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family AA_permease_2 PF13520.6 EPE33018.1 - 1.7e-62 211.6 48.4 2.1e-62 211.4 48.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE33018.1 - 6.2e-24 84.4 42.7 8.3e-24 84.0 42.7 1.1 1 0 0 1 1 1 1 Amino acid permease NUDE_C PF04880.13 EPE33019.1 - 1.6e-45 155.8 15.5 1.6e-45 155.8 15.5 4.1 2 1 3 5 5 2 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 EPE33019.1 - 0.0049 17.3 6.1 0.0049 17.3 6.1 4.2 3 1 1 4 4 4 1 Cell division protein ZapB CLZ PF16526.5 EPE33019.1 - 0.0071 16.7 3.8 0.0071 16.7 3.8 4.6 3 2 2 5 5 5 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 EPE33019.1 - 0.13 12.8 3.0 4 8.0 0.0 3.3 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 EPE33019.1 - 0.16 12.3 5.5 3.8 8.0 0.0 3.9 3 2 0 4 4 4 0 Lipoprotein leucine-zipper ERM PF00769.19 EPE33019.1 - 0.22 11.3 28.7 0.46 10.3 28.7 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family GrpE PF01025.19 EPE33019.1 - 0.46 10.1 30.5 0.25 11.0 9.8 3.5 2 1 2 4 4 4 0 GrpE Fez1 PF06818.15 EPE33019.1 - 0.51 10.8 26.2 6.1 7.2 11.6 3.1 2 1 1 3 3 3 0 Fez1 ATG16 PF08614.11 EPE33019.1 - 0.77 9.9 34.9 3.6 7.8 17.1 3.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF745 PF05335.13 EPE33019.1 - 0.9 9.2 17.6 0.12 12.0 13.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TPR_MLP1_2 PF07926.12 EPE33019.1 - 1.2 9.2 37.8 0.12 12.4 12.1 4.2 2 1 1 3 3 2 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 EPE33019.1 - 1.8 8.7 31.8 10 6.3 20.5 4.1 2 1 1 3 3 3 0 Tropomyosin like EAP30 PF04157.16 EPE33019.1 - 2.2 7.5 8.0 17 4.6 2.4 3.1 2 1 2 4 4 4 0 EAP30/Vps36 family PSII_Pbs27 PF13326.6 EPE33019.1 - 2.2 8.6 9.1 0.83 10.0 5.0 2.1 2 0 0 2 2 2 0 Photosystem II Pbs27 Prefoldin_2 PF01920.20 EPE33019.1 - 2.7 8.0 31.9 0.67 9.9 5.2 5.3 2 1 2 5 5 5 0 Prefoldin subunit PRKG1_interact PF15898.5 EPE33019.1 - 3.1 8.8 24.5 1.5 9.8 11.0 3.4 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF16 PF01519.16 EPE33019.1 - 4 8.0 16.7 0.15 12.6 6.0 2.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF3584 PF12128.8 EPE33019.1 - 4.8 4.6 23.7 8.2 3.8 23.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_II PF06009.12 EPE33019.1 - 8.3 6.4 15.2 4.2 7.4 6.9 3.7 2 1 2 4 4 4 0 Laminin Domain II PIF1 PF05970.14 EPE33021.1 - 4.9e-62 210.2 0.9 3.6e-59 200.8 0.9 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EPE33021.1 - 1.3e-21 77.2 0.0 2.5e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPE33021.1 - 1.1e-09 38.8 0.0 2.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EPE33021.1 - 2.3e-05 24.0 0.1 5.1e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EPE33021.1 - 0.00015 22.1 0.0 0.00043 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPE33021.1 - 0.00043 20.7 0.0 0.0039 17.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 EPE33021.1 - 0.00049 19.2 0.1 0.0011 18.1 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 EPE33021.1 - 0.00059 20.3 0.1 0.0014 19.1 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EPE33021.1 - 0.00086 18.8 0.2 0.0089 15.5 0.0 2.5 3 0 0 3 3 3 1 PhoH-like protein Herpes_Helicase PF02689.14 EPE33021.1 - 0.0012 16.9 0.1 0.0083 14.1 0.0 1.9 2 0 0 2 2 2 1 Helicase RsgA_GTPase PF03193.16 EPE33021.1 - 0.0073 16.2 0.1 0.017 15.0 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EPE33021.1 - 0.0073 16.8 0.4 0.039 14.5 0.0 2.3 1 1 1 2 2 2 1 ABC transporter DUF2075 PF09848.9 EPE33021.1 - 0.0081 15.4 0.1 0.016 14.5 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EPE33021.1 - 0.0082 16.2 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD_C_2 PF13538.6 EPE33021.1 - 0.0086 15.9 0.0 0.027 14.3 0.0 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain RNA_helicase PF00910.22 EPE33021.1 - 0.012 16.0 0.0 0.039 14.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EPE33021.1 - 0.024 14.0 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 EPE33021.1 - 0.026 14.3 0.1 0.22 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain SH3_13 PF18335.1 EPE33021.1 - 0.028 14.2 0.6 0.22 11.4 0.1 2.6 3 0 0 3 3 2 0 ATP-dependent RecD-like DNA helicase SH3 domain NACHT PF05729.12 EPE33021.1 - 0.029 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 EPE33021.1 - 0.052 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 EPE33021.1 - 0.053 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 EPE33021.1 - 0.068 12.1 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 EPE33021.1 - 0.07 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 EPE33021.1 - 0.078 11.9 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.22 EPE33021.1 - 0.08 12.1 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.14 EPE33021.1 - 0.13 12.3 0.2 1.3 9.0 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TEX33 PF15400.6 EPE33021.1 - 0.14 12.6 1.3 1.9 9.0 0.4 2.5 2 0 0 2 2 2 0 Testis-expressed sequence 33 protein family YjeF_N PF03853.15 EPE33022.1 - 4.9e-36 124.2 0.0 7.3e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EPE33022.1 - 3.3e-08 34.4 0.7 3.3e-08 34.4 0.7 2.1 2 0 0 2 2 2 1 FDF domain APH PF01636.23 EPE33023.1 - 4.3e-09 36.7 0.0 6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EPE33023.1 - 0.0071 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 EPE33023.1 - 0.052 13.1 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-C3HC4_3 PF13920.6 EPE33024.1 - 1.3e-09 37.7 5.3 1.8e-09 37.3 5.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE33024.1 - 3.4e-08 33.2 9.7 5.3e-08 32.6 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE33024.1 - 1.6e-07 31.0 9.1 2.9e-07 30.2 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE33024.1 - 2.4e-07 31.0 8.1 3.7e-07 30.4 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EPE33024.1 - 1.9e-05 24.5 8.7 2.9e-05 23.9 8.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EPE33024.1 - 7.5e-05 22.5 5.2 0.00014 21.6 5.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 EPE33024.1 - 0.00014 22.1 4.0 0.037 14.3 0.4 2.6 2 1 0 2 2 2 2 zinc-ribbon zf-RING_UBOX PF13445.6 EPE33024.1 - 0.00037 20.4 5.9 0.00077 19.4 5.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EPE33024.1 - 0.0024 18.0 8.9 0.0037 17.4 8.9 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EPE33024.1 - 0.081 12.7 5.8 0.22 11.3 5.8 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 EPE33024.1 - 0.14 12.0 7.9 0.56 10.0 7.8 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF4238 PF14022.6 EPE33024.1 - 0.2 11.1 1.7 0.27 10.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) zf-MIZ PF02891.20 EPE33024.1 - 0.76 9.6 6.6 1.8 8.3 6.5 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.7 EPE33024.1 - 3.2 8.1 8.0 12 6.3 8.0 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain Snapin_Pallidin PF14712.6 EPE33025.1 - 0.014 15.8 1.0 0.053 13.9 0.1 2.2 2 1 0 2 2 2 0 Snapin/Pallidin Jnk-SapK_ap_N PF09744.9 EPE33025.1 - 0.032 14.5 2.5 3.1 8.0 0.2 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 EPE33025.1 - 0.29 9.6 0.8 0.33 9.4 0.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family bZIP_1 PF00170.21 EPE33025.1 - 0.55 10.4 3.6 3.3 7.9 0.1 2.3 2 1 0 2 2 2 0 bZIP transcription factor DUF1188 PF06690.11 EPE33027.1 - 0.06 12.9 1.0 0.1 12.2 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) AC_N PF16214.5 EPE33027.1 - 0.18 10.9 2.7 0.19 10.8 2.7 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region TMPIT PF07851.13 EPE33027.1 - 2.6 7.2 5.2 2.9 7.1 5.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein TSP_NTD PF17804.1 EPE33028.1 - 0.022 15.0 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain NEMO PF11577.8 EPE33028.1 - 0.054 13.5 3.3 0.12 12.4 3.3 1.5 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO QRPTase_C PF01729.19 EPE33028.1 - 0.14 11.9 0.2 0.23 11.2 0.2 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Hydantoinase_A PF01968.18 EPE33029.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Suc_Fer-like PF06999.12 EPE33030.1 - 9e-72 241.1 0.0 1.1e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like MFS_1 PF07690.16 EPE33031.1 - 1.3e-23 83.5 27.7 2e-23 82.9 27.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UCR_hinge PF02320.16 EPE33032.1 - 7.5e-26 90.1 12.8 7.5e-26 90.1 12.8 1.6 2 0 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein Nop14 PF04147.12 EPE33032.1 - 0.087 11.0 16.9 0.09 11.0 16.9 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4471 PF14740.6 EPE33032.1 - 0.26 10.5 2.8 0.34 10.1 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) CDC27 PF09507.10 EPE33032.1 - 0.34 10.2 14.8 0.36 10.2 14.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 EPE33032.1 - 0.46 10.3 12.6 0.51 10.1 12.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP70 PF00012.20 EPE33032.1 - 0.52 8.4 8.5 0.64 8.1 8.5 1.1 1 0 0 1 1 1 0 Hsp70 protein SDA1 PF05285.12 EPE33032.1 - 0.61 9.5 17.6 0.65 9.4 17.6 1.1 1 0 0 1 1 1 0 SDA1 Pox_Ag35 PF03286.14 EPE33032.1 - 0.71 9.6 15.6 0.92 9.3 15.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF740 PF05340.12 EPE33032.1 - 1.5 7.5 11.7 1.8 7.2 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF913 PF06025.12 EPE33032.1 - 2.1 7.3 5.1 2.1 7.2 5.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 EPE33032.1 - 3.4 5.8 13.3 3.8 5.7 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 EPE33032.1 - 3.4 6.3 6.1 3.4 6.4 6.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.15 EPE33032.1 - 5.4 5.7 6.9 5.5 5.7 6.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tim54 PF11711.8 EPE33032.1 - 5.8 5.6 9.9 6.5 5.4 9.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PBP1_TM PF14812.6 EPE33032.1 - 9 6.7 10.3 15 6.1 10.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Presenilin PF01080.17 EPE33032.1 - 9.8 4.8 8.5 10 4.8 8.5 1.1 1 0 0 1 1 1 0 Presenilin Vps36_ESCRT-II PF11605.8 EPE33033.1 - 0.19 12.0 0.0 0.73 10.1 0.0 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 RraA-like PF03737.15 EPE33035.1 - 8.9e-27 94.1 0.1 1.1e-26 93.8 0.1 1.1 1 0 0 1 1 1 1 Aldolase/RraA Drf_GBD PF06371.13 EPE33036.1 - 4.5e-18 65.5 0.8 2.5e-16 59.8 0.8 2.6 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Hydrophobin_2 PF06766.11 EPE33037.1 - 1.9e-08 34.1 5.8 2.6e-08 33.7 5.8 1.3 1 0 0 1 1 1 1 Fungal hydrophobin ZZ PF00569.17 EPE33038.1 - 0.00034 20.4 10.2 0.00061 19.6 10.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 EPE33038.1 - 0.00035 20.8 5.6 0.0007 19.9 5.6 1.5 1 0 0 1 1 1 1 C1 domain Helo_like_N PF17111.5 EPE33038.1 - 0.059 12.7 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF842 PF05811.13 EPE33039.1 - 0.00093 18.9 1.2 0.19 11.4 0.8 4.0 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF842) Apolipoprotein PF01442.18 EPE33039.1 - 2.4 8.0 39.3 0.61 9.9 6.1 7.0 5 2 0 6 6 6 0 Apolipoprotein A1/A4/E domain Glyco_tran_WecB PF03808.13 EPE33039.1 - 3.9 7.4 16.8 3 7.8 0.1 6.1 5 2 1 7 7 7 0 Glycosyl transferase WecB/TagA/CpsF family Prominin PF05478.11 EPE33039.1 - 7.6 4.4 8.6 1.4 6.8 4.3 1.9 2 0 0 2 2 2 0 Prominin YajC PF02699.15 EPE33042.1 - 0.0019 18.0 0.2 0.0061 16.4 0.2 1.8 1 0 0 1 1 1 1 Preprotein translocase subunit RIFIN PF02009.16 EPE33042.1 - 0.0046 16.9 4.4 0.0046 16.9 4.4 2.1 1 1 0 2 2 2 1 Rifin Exonuc_VII_L PF02601.15 EPE33042.1 - 0.0079 15.8 10.9 0.013 15.1 10.9 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF5436 PF17504.2 EPE33042.1 - 0.019 15.3 0.1 0.031 14.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5436) AAA_13 PF13166.6 EPE33042.1 - 0.075 11.7 7.4 0.1 11.3 7.4 1.1 1 0 0 1 1 1 0 AAA domain Orf78 PF06024.12 EPE33042.1 - 0.077 13.3 0.1 0.077 13.3 0.1 2.7 2 1 0 2 2 1 0 Orf78 (ac78) 7TM_GPCR_Srw PF10324.9 EPE33042.1 - 0.17 11.1 0.1 0.26 10.5 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw AIP3 PF03915.13 EPE33042.1 - 0.58 9.2 9.9 1 8.4 9.9 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 DUF842 PF05811.13 EPE33042.1 - 1.1 8.9 11.4 2.2 8.0 11.4 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF3584 PF12128.8 EPE33042.1 - 2.2 5.7 14.7 2.9 5.3 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GREB1 PF15782.5 EPE33042.1 - 2.5 5.1 15.7 3.2 4.8 15.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Apt1 PF10351.9 EPE33042.1 - 4.4 6.1 9.9 6.4 5.5 9.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain MT0933_antitox PF14013.6 EPE33042.1 - 5.3 7.4 7.4 9.7 6.6 1.3 3.0 1 1 1 2 2 2 0 MT0933-like antitoxin protein HSD3 PF15244.6 EPE33042.1 - 5.6 6.4 14.5 11 5.4 14.5 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 Neur_chan_memb PF02932.16 EPE33042.1 - 6.3 6.8 8.4 20 5.2 8.1 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Mitofilin PF09731.9 EPE33042.1 - 6.5 5.5 27.6 8.2 5.1 26.4 1.6 1 1 1 2 2 2 0 Mitochondrial inner membrane protein OmpH PF03938.14 EPE33042.1 - 8.9 6.6 20.1 18 5.7 20.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-C2H2 PF00096.26 EPE33043.1 - 7.9e-06 26.1 14.4 0.0027 18.1 3.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE33043.1 - 0.00049 20.7 12.0 0.16 12.9 2.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EPE33043.1 - 0.053 14.1 1.3 0.11 13.1 1.3 1.5 1 0 0 1 1 1 0 FOXP coiled-coil domain Egh16-like PF11327.8 EPE33044.1 - 9.8e-21 75.0 8.9 9.8e-21 75.0 8.9 2.1 2 2 0 2 2 2 1 Egh16-like virulence factor ABC_tran PF00005.27 EPE33045.1 - 1.8e-41 141.8 0.1 8.9e-20 71.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPE33045.1 - 5.9e-33 114.7 27.9 1e-23 84.4 14.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region T2SSE PF00437.20 EPE33045.1 - 1.2e-12 47.5 0.2 3.5e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.6 EPE33045.1 - 5.6e-10 39.5 6.7 0.00075 19.4 0.1 3.6 3 1 1 4 4 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPE33045.1 - 6.7e-10 38.8 3.4 2.1e-05 24.1 0.3 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EPE33045.1 - 8.8e-09 35.0 1.0 0.00091 18.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EPE33045.1 - 2.5e-08 34.6 1.4 3.2e-05 24.5 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EPE33045.1 - 5.1e-08 33.3 0.1 0.0089 16.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 EPE33045.1 - 1.8e-07 31.2 0.1 0.00074 19.6 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EPE33045.1 - 5.7e-07 29.1 0.7 0.017 14.5 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.6 EPE33045.1 - 1.4e-06 28.8 0.8 0.041 14.3 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EPE33045.1 - 2.2e-06 27.7 1.7 0.026 14.4 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 EPE33045.1 - 3.6e-06 27.2 0.1 0.12 12.6 0.1 3.2 2 1 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 EPE33045.1 - 3.8e-05 23.7 0.6 0.039 13.9 0.0 2.5 2 0 0 2 2 2 1 NTPase Adeno_IVa2 PF02456.15 EPE33045.1 - 4.4e-05 22.5 1.2 0.00058 18.8 0.2 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein Dynamin_N PF00350.23 EPE33045.1 - 6e-05 23.2 0.2 0.043 13.9 0.1 2.5 2 0 0 2 2 2 1 Dynamin family cobW PF02492.19 EPE33045.1 - 6.2e-05 22.7 2.0 0.11 12.1 0.5 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EPE33045.1 - 0.00011 22.8 0.1 0.8 10.3 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EPE33045.1 - 0.00013 21.6 0.4 0.28 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EPE33045.1 - 0.00013 21.7 0.1 0.13 12.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.18 EPE33045.1 - 0.0003 20.6 0.8 0.42 10.3 0.1 2.7 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 EPE33045.1 - 0.00032 20.0 0.1 0.79 9.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.12 EPE33045.1 - 0.00038 20.4 1.3 0.42 10.5 0.1 2.8 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.6 EPE33045.1 - 0.00045 20.0 1.7 0.71 9.5 0.4 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 EPE33045.1 - 0.00059 19.9 0.1 1.8 8.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EPE33045.1 - 0.001 18.7 0.1 0.14 11.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase_2 PF01637.18 EPE33045.1 - 0.0022 18.0 0.0 1.3 8.9 0.0 2.8 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 EPE33045.1 - 0.0029 16.5 3.2 1.1 7.9 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF87 PF01935.17 EPE33045.1 - 0.0032 17.6 5.2 0.34 11.0 0.3 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 EPE33045.1 - 0.0033 16.4 0.5 0.71 8.7 0.2 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain SbcCD_C PF13558.6 EPE33045.1 - 0.0036 17.5 5.0 1.8 8.9 0.7 3.8 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 EPE33045.1 - 0.0038 17.6 0.1 1.8 9.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 EPE33045.1 - 0.013 15.5 1.1 0.73 9.7 0.0 3.3 4 0 0 4 4 2 0 Rad17 P-loop domain IstB_IS21 PF01695.17 EPE33045.1 - 0.013 15.3 0.3 8.4 6.1 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_24 PF13479.6 EPE33045.1 - 0.013 15.2 0.0 0.81 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EPE33045.1 - 0.013 15.2 0.1 1.3 8.7 0.0 2.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 EPE33045.1 - 0.014 14.8 0.0 3.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Guanylate_kin PF00625.21 EPE33045.1 - 0.015 15.0 0.5 0.16 11.6 0.1 2.2 2 0 0 2 2 2 0 Guanylate kinase AAA_11 PF13086.6 EPE33045.1 - 0.019 14.8 0.1 0.11 12.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EPE33045.1 - 0.023 15.1 0.8 3.3 8.0 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EPE33045.1 - 0.028 14.4 0.9 22 5.1 0.1 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EPE33045.1 - 0.03 14.7 0.2 3.8 7.9 0.1 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 EPE33045.1 - 0.034 14.2 0.8 2.2 8.3 0.0 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_27 PF13514.6 EPE33045.1 - 0.034 13.7 0.1 0.34 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 EPE33045.1 - 0.051 12.7 0.9 2.2 7.4 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 CLP1_P PF16575.5 EPE33045.1 - 0.062 13.1 0.2 3.3 7.5 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Septin PF00735.18 EPE33045.1 - 0.089 12.1 0.2 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_10 PF12846.7 EPE33045.1 - 0.13 11.2 0.0 15 4.4 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.17 EPE33045.1 - 0.14 12.0 0.3 15 5.2 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 EPE33045.1 - 0.15 12.3 0.3 11 6.2 0.1 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 EPE33045.1 - 0.15 12.1 0.3 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EPE33045.1 - 0.15 12.3 0.9 3.5 7.8 0.4 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EPE33045.1 - 0.17 11.1 0.6 21 4.2 0.0 3.0 3 0 0 3 3 2 0 NB-ARC domain RNA12 PF10443.9 EPE33045.1 - 0.19 10.4 0.7 5 5.7 0.1 2.3 2 0 0 2 2 2 0 RNA12 protein DUF2075 PF09848.9 EPE33045.1 - 0.21 10.8 0.1 8.8 5.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Pox_A32 PF04665.12 EPE33045.1 - 0.21 11.0 3.4 0.84 9.1 0.2 2.6 3 0 0 3 3 2 0 Poxvirus A32 protein PduV-EutP PF10662.9 EPE33045.1 - 0.23 11.2 1.0 17 5.1 0.2 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 EPE33045.1 - 1.2 9.1 3.7 25 4.8 0.2 2.7 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B adh_short PF00106.25 EPE33046.1 - 1.5e-23 83.3 0.0 2.1e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE33046.1 - 3.3e-16 59.6 0.0 4.5e-16 59.1 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE33046.1 - 6.4e-06 26.2 0.1 9.3e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EPE33046.1 - 0.0051 16.3 0.1 0.019 14.4 0.1 1.9 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase T2SSE PF00437.20 EPE33046.1 - 0.027 13.5 0.1 0.04 13.0 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NAD_binding_10 PF13460.6 EPE33046.1 - 0.031 14.2 0.0 0.041 13.8 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding DUF3268 PF11672.8 EPE33048.1 - 0.037 14.4 1.0 0.11 12.9 0.4 2.1 2 0 0 2 2 2 0 zinc-finger-containing domain Ogr_Delta PF04606.12 EPE33048.1 - 0.096 12.7 1.5 0.28 11.2 1.5 1.8 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger KTI12 PF08433.10 EPE33049.1 - 4.9e-75 252.5 0.0 6.2e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EPE33049.1 - 0.00023 21.3 0.0 0.00043 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EPE33049.1 - 0.077 13.5 0.0 0.23 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EPE33049.1 - 0.09 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EPE33049.1 - 0.13 12.3 0.0 0.82 9.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain ThiS-like PF14453.6 EPE33049.1 - 0.2 11.7 0.0 0.48 10.5 0.0 1.6 1 0 0 1 1 1 0 ThiS-like ubiquitin G-alpha PF00503.20 EPE33051.1 - 5.4e-122 407.3 4.8 6.3e-122 407.1 4.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EPE33051.1 - 1e-14 54.4 1.9 2.8e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 EPE33051.1 - 5.7e-05 22.8 0.0 0.00025 20.8 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 EPE33051.1 - 0.0049 16.3 5.2 0.073 12.4 0.2 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 EPE33051.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EPE33051.1 - 0.017 15.4 0.3 2.2 8.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EPE33051.1 - 0.07 13.2 0.1 8.6 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EPE33051.1 - 0.08 12.5 0.1 1 8.9 0.1 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Ly49 PF08391.10 EPE33052.1 - 0.53 10.7 3.2 0.71 10.2 3.2 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF543 PF04418.12 EPE33053.1 - 1.1e-28 99.0 0.0 1.3e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.9 EPE33054.1 - 4.1e-63 213.0 2.5 1.8e-62 211.0 1.3 2.7 1 1 1 2 2 2 1 Urb2/Npa2 family IF-2 PF11987.8 EPE33054.1 - 0.21 11.7 0.9 2 8.6 0.1 2.6 2 0 0 2 2 2 0 Translation-initiation factor 2 BUD22 PF09073.10 EPE33054.1 - 2.6 7.3 8.4 0.088 12.1 1.8 1.8 2 0 0 2 2 2 0 BUD22 Say1_Mug180 PF10340.9 EPE33055.1 - 8.1e-07 28.2 0.0 1.2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 EPE33055.1 - 2.1e-05 25.3 1.3 3e-05 24.8 0.7 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EPE33055.1 - 2.4e-05 24.3 0.1 5e-05 23.3 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 EPE33055.1 - 0.00016 20.7 0.0 0.00024 20.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 EPE33055.1 - 0.00082 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE33055.1 - 0.12 12.0 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sec10 PF07393.11 EPE33056.1 - 3.4e-160 534.8 0.0 4.2e-160 534.5 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 EPE33056.1 - 2.2e-06 27.4 0.1 5.3e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPE33056.1 - 3.8e-06 26.7 0.1 3.1e-05 23.8 0.1 2.4 2 0 0 2 2 2 1 F-box-like Eisosome1 PF12757.7 EPE33057.1 - 9.9e-43 145.4 11.5 9.9e-43 145.4 11.5 4.9 2 2 2 4 4 4 1 Eisosome protein 1 Y_phosphatase3 PF13350.6 EPE33058.1 - 3.7e-38 131.8 0.0 5.3e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EPE33058.1 - 6e-06 25.9 0.0 1.8e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 EPE33058.1 - 0.0008 18.4 0.2 0.0071 15.3 0.1 1.9 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 EPE33058.1 - 0.002 17.7 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EPE33058.1 - 0.0037 17.1 0.3 0.11 12.3 0.0 2.5 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain zf-RING_2 PF13639.6 EPE33059.1 - 1.7e-05 25.0 11.6 1.7e-05 25.0 11.6 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EPE33059.1 - 0.00025 20.9 9.9 0.00025 20.9 9.9 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EPE33059.1 - 0.0024 17.7 12.0 0.0024 17.7 12.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE33059.1 - 0.0053 16.8 8.8 0.0053 16.8 8.8 2.4 3 0 0 3 3 3 1 RING-type zinc-finger DUF3015 PF11220.8 EPE33059.1 - 0.16 11.9 0.0 0.71 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) DUF4451 PF14616.6 EPE33059.1 - 0.17 12.1 5.3 0.77 10.0 0.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) zf-RING_4 PF14570.6 EPE33059.1 - 0.43 10.4 10.7 1.1 9.1 8.6 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EPE33059.1 - 1 9.2 7.9 6.1 6.7 7.9 2.3 1 1 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 EPE33059.1 - 2.2 8.2 16.3 1.1 9.2 10.5 3.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 ABC_membrane PF00664.23 EPE33060.1 - 6.5e-51 173.6 35.9 4.5e-30 105.2 14.9 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EPE33060.1 - 7.9e-48 162.4 0.1 2.2e-26 93.0 0.0 3.2 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 EPE33060.1 - 1.2e-05 25.3 1.2 0.044 13.9 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 EPE33060.1 - 3.2e-05 23.5 2.9 0.096 12.1 0.4 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EPE33060.1 - 0.00017 21.5 0.9 1.2 8.9 0.2 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EPE33060.1 - 0.00024 21.0 0.4 0.42 10.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EPE33060.1 - 0.00028 20.6 2.4 0.23 11.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EPE33060.1 - 0.00036 21.0 0.0 0.61 10.5 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EPE33060.1 - 0.00079 18.7 0.0 0.041 13.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 EPE33060.1 - 0.0031 18.1 10.6 0.17 12.4 0.0 4.1 4 0 0 4 4 4 2 AAA domain DUF87 PF01935.17 EPE33060.1 - 0.0056 16.8 2.8 0.18 11.9 0.5 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain Roc PF08477.13 EPE33060.1 - 0.0093 16.2 0.1 1.7 8.9 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 EPE33060.1 - 0.015 15.2 0.1 4.6 7.1 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 EPE33060.1 - 0.016 15.5 1.4 4.5 7.6 0.1 3.3 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 EPE33060.1 - 0.02 13.9 0.8 3.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EPE33060.1 - 0.024 14.4 1.9 4.5 6.9 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EPE33060.1 - 0.074 12.8 0.0 0.85 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EPE33060.1 - 0.11 12.2 0.0 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 EPE33060.1 - 0.12 11.9 0.6 1.7 8.1 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 EPE33060.1 - 0.18 11.7 0.4 2 8.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EPE33060.1 - 0.2 11.9 0.8 0.88 9.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EPE33060.1 - 0.96 9.5 9.5 0.2 11.7 0.1 2.9 3 0 0 3 3 2 0 Dynamin family Pkinase PF00069.25 EPE33061.1 - 1.5e-64 217.9 0.0 1.8e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE33061.1 - 8.3e-33 113.8 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE33061.1 - 0.0005 19.5 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EPE33061.1 - 0.087 11.8 0.0 2.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Frag1 PF10277.9 EPE33062.1 - 1.1e-46 159.2 17.0 1.2e-46 159.0 17.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family TrbC PF04956.13 EPE33062.1 - 0.0097 16.1 0.8 0.0097 16.1 0.8 1.9 2 0 0 2 2 2 1 TrbC/VIRB2 family DUF998 PF06197.13 EPE33062.1 - 0.047 13.3 11.8 0.17 11.5 11.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF998) Pox_A14 PF05767.12 EPE33062.1 - 4.7 7.4 7.0 0.4 10.9 0.3 2.5 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 YwiC PF14256.6 EPE33062.1 - 8.3 6.7 10.8 1.7 9.0 2.1 2.5 1 1 1 2 2 2 0 YwiC-like protein DUF2070 PF09843.9 EPE33062.1 - 8.9 4.5 11.6 13 4.0 11.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SNF2_N PF00176.23 EPE33063.1 - 2.4e-56 191.0 0.3 4.3e-56 190.1 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 EPE33063.1 - 2e-08 33.9 7.2 3.9e-08 33.0 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE33063.1 - 9.4e-08 31.8 7.3 1.8e-07 30.9 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPE33063.1 - 9.7e-08 31.8 7.5 1.9e-07 30.9 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE33063.1 - 1.3e-06 28.7 9.6 2.4e-06 27.8 9.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EPE33063.1 - 1.9e-05 24.6 3.1 2.3e-05 24.3 1.7 2.0 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EPE33063.1 - 1.9e-05 24.4 7.3 4.5e-05 23.2 7.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EPE33063.1 - 8.3e-05 22.5 8.0 0.00015 21.6 8.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.31 EPE33063.1 - 0.00024 21.4 0.0 0.00061 20.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE33063.1 - 0.0076 16.3 0.0 0.037 14.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-rbx1 PF12678.7 EPE33063.1 - 0.015 15.6 11.4 0.051 13.9 11.4 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EPE33063.1 - 0.017 15.3 7.6 0.041 14.1 7.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 EPE33063.1 - 0.029 14.3 1.0 0.068 13.1 1.0 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Sec34 PF04136.15 EPE33063.1 - 0.06 13.2 0.3 0.16 11.9 0.3 1.6 1 0 0 1 1 1 0 Sec34-like family Focal_AT PF03623.13 EPE33063.1 - 0.067 13.2 0.2 0.29 11.1 0.2 2.1 1 0 0 1 1 1 0 Focal adhesion targeting region Glu-tRNAGln PF02686.15 EPE33063.1 - 0.098 13.0 0.1 0.79 10.1 0.0 2.7 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit zf-P11 PF03854.14 EPE33063.1 - 0.22 11.2 5.4 0.58 9.9 5.4 1.7 1 0 0 1 1 1 0 P-11 zinc finger DZR PF12773.7 EPE33063.1 - 2 8.5 4.8 4.5 7.4 4.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon UPF0242 PF06785.11 EPE33063.1 - 3 7.9 8.4 0.85 9.7 1.5 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus p450 PF00067.22 EPE33065.1 - 1.3e-58 198.9 0.0 1.6e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EPE33066.1 - 7.3e-38 130.5 0.0 1.1e-37 129.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Band_7 PF01145.25 EPE33067.1 - 1.8e-25 90.0 2.4 2.7e-25 89.4 2.4 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family DLH PF01738.18 EPE33068.1 - 4.1e-26 91.9 0.0 5.3e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EPE33068.1 - 0.028 13.9 0.0 0.059 12.8 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EPE33068.1 - 0.1 12.2 0.0 1.5 8.4 0.0 2.1 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Epimerase PF01370.21 EPE33069.1 - 2.6e-11 43.5 0.1 5.3e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPE33069.1 - 3.6e-11 43.1 0.2 5.5e-11 42.5 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE33069.1 - 1.8e-08 34.5 0.1 4.3e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EPE33069.1 - 8e-06 26.3 0.2 3.6e-05 24.2 0.1 2.1 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EPE33069.1 - 0.00012 21.2 0.2 0.13 11.2 0.2 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.16 EPE33069.1 - 0.076 13.7 0.0 0.19 12.5 0.0 1.7 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 EPE33069.1 - 0.085 13.0 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Fungal_trans_2 PF11951.8 EPE33070.1 - 1e-06 27.9 0.1 1.5e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gpr1_Fun34_YaaH PF01184.19 EPE33071.1 - 2.3e-30 105.8 20.7 3.3e-30 105.2 20.7 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ran_BP1 PF00638.18 EPE33072.1 - 8.9e-16 58.3 0.5 3.3e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 RanBP1 domain Yip1 PF04893.17 EPE33073.1 - 6.7e-15 55.2 11.0 9.7e-15 54.7 11.0 1.4 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 EPE33073.1 - 0.72 9.6 8.2 1.3 8.7 8.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) DUF2070 PF09843.9 EPE33073.1 - 5 5.3 7.8 6.1 5.0 7.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PAS_3 PF08447.12 EPE33074.1 - 4e-14 52.7 0.0 1.4e-08 34.9 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 EPE33074.1 - 2.3e-09 37.4 0.0 6.7e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 EPE33074.1 - 5.9e-08 32.7 0.0 0.0006 19.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 EPE33074.1 - 9.7e-05 22.6 0.0 0.049 13.9 0.0 3.3 3 0 0 3 3 3 1 PAS fold PAS_11 PF14598.6 EPE33074.1 - 0.0011 19.0 0.0 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 PAS domain WD40 PF00400.32 EPE33075.1 - 1.1e-16 60.9 2.1 1e-05 26.1 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE33075.1 - 0.00023 21.4 0.2 1.6 9.1 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Thioredoxin PF00085.20 EPE33076.1 - 2.8e-45 152.5 0.1 1e-24 86.4 0.0 4.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EPE33076.1 - 5.7e-09 36.1 0.0 4.6e-05 23.4 0.0 4.2 2 1 2 4 4 4 1 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EPE33076.1 - 3.5e-06 27.4 1.6 2.5 8.6 0.1 4.5 3 2 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EPE33076.1 - 0.00014 22.1 0.0 0.077 13.3 0.0 3.7 3 1 0 3 3 3 1 Thioredoxin-like HyaE PF07449.11 EPE33076.1 - 0.0029 17.5 0.0 2.5 8.1 0.0 3.0 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 EPE33076.1 - 0.0065 16.4 0.6 0.067 13.1 0.0 2.8 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EPE33076.1 - 0.0075 16.4 0.3 0.031 14.4 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like MRP-L46 PF11788.8 EPE33076.1 - 0.12 13.1 0.9 0.36 11.6 0.9 1.8 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Tyr-DNA_phospho PF06087.12 EPE33077.1 - 1.4e-158 528.2 0.0 1.6e-158 528.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EPE33077.1 - 0.00047 20.0 0.4 0.29 11.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EPE33077.1 - 0.13 12.5 0.8 2.3 8.6 0.6 2.4 2 0 0 2 2 2 0 Phospholipase D Active site motif ACBP PF00887.19 EPE33078.1 - 3.2e-21 75.3 0.6 3.7e-21 75.1 0.6 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein MOSC PF03473.17 EPE33079.1 - 9.6e-25 87.1 0.0 2.2e-24 86.0 0.0 1.6 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 EPE33079.1 - 1.6e-11 44.1 0.0 3.2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain 4HBT PF03061.22 EPE33081.1 - 2e-13 50.5 0.1 4.3e-13 49.4 0.0 1.6 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 EPE33081.1 - 0.0018 18.6 0.0 0.0024 18.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily HupF_HypC PF01455.18 EPE33081.1 - 0.12 12.5 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 HupF/HypC family MaoC_dehydratas PF01575.19 EPE33081.1 - 0.19 11.3 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain FA_desaturase PF00487.24 EPE33082.1 - 2.2e-18 67.0 12.7 2.2e-18 67.0 12.7 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EPE33082.1 - 2.8e-17 62.6 0.1 6.1e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Xan_ur_permease PF00860.20 EPE33083.1 - 1.8e-64 217.9 40.8 4.3e-63 213.3 40.8 2.0 1 1 0 1 1 1 1 Permease family SMC_N PF02463.19 EPE33084.1 - 6.9e-71 238.2 0.0 4.3e-70 235.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EPE33084.1 - 1.9e-20 73.3 0.2 1.9e-20 73.3 0.2 2.6 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EPE33084.1 - 6.4e-10 39.9 13.2 6.4e-10 39.9 13.2 6.2 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 EPE33084.1 - 1.4e-08 34.9 5.7 0.0016 18.3 0.0 3.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EPE33084.1 - 0.001 18.7 0.1 0.0024 17.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CxC4 PF18717.1 EPE33084.1 - 0.062 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases ABC_tran PF00005.27 EPE33084.1 - 0.062 13.8 0.0 0.062 13.8 0.0 6.1 4 2 0 4 4 4 0 ABC transporter Fungal_trans_2 PF11951.8 EPE33086.1 - 3.5e-15 55.7 2.5 5.9e-15 55.0 2.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE33086.1 - 1.8e-08 34.3 9.1 3.2e-08 33.6 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NOT2_3_5 PF04153.18 EPE33087.1 - 1.4e-30 106.1 0.9 2.5e-30 105.2 0.9 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CUE PF02845.16 EPE33088.1 - 3.4e-12 45.8 0.0 5.3e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 CUE domain Cue1_U7BR PF18499.1 EPE33088.1 - 0.013 15.5 2.6 0.023 14.7 2.6 1.5 1 1 0 1 1 1 0 Ubc7p-binding region of Cue1 G2BR PF18442.1 EPE33088.1 - 0.058 13.0 7.0 0.12 12.0 7.0 1.5 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) ketoacyl-synt PF00109.26 EPE33089.1 - 2.4e-61 207.5 1.1 5.1e-60 203.2 0.1 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EPE33089.1 - 2.4e-35 121.1 0.4 4.7e-35 120.1 0.4 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EPE33089.1 - 8.8e-07 28.5 0.2 1.2e-05 24.8 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EPE33089.1 - 0.2 12.1 0.2 0.41 11.1 0.2 1.5 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension DUF3328 PF11807.8 EPE33090.1 - 6.7e-34 117.6 0.3 9e-34 117.2 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PhyH PF05721.13 EPE33092.1 - 3.5e-15 56.8 0.0 4.8e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4406 PF14359.6 EPE33092.1 - 0.16 12.4 0.0 0.32 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) zf-CHCC PF10276.9 EPE33093.1 - 5.2e-16 58.4 1.6 7.9e-16 57.8 1.6 1.3 1 0 0 1 1 1 1 Zinc-finger domain zf-C2H2_4 PF13894.6 EPE33093.1 - 0.52 11.3 3.3 0.96 10.5 3.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger MPP6 PF10175.9 EPE33094.1 - 5.1e-06 27.0 19.8 0.0024 18.4 19.9 3.1 1 1 0 1 1 1 1 M-phase phosphoprotein 6 YL1 PF05764.13 EPE33094.1 - 0.0099 16.0 10.1 0.0099 16.0 10.1 2.0 2 1 0 2 2 2 1 YL1 nuclear protein SR-25 PF10500.9 EPE33094.1 - 0.099 12.2 15.4 0.014 15.0 11.2 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.12 EPE33094.1 - 0.16 11.6 20.9 0.096 12.4 19.1 1.3 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SEEEED PF14797.6 EPE33094.1 - 0.46 10.7 19.3 0.89 9.7 19.3 1.4 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex CDC45 PF02724.14 EPE33094.1 - 0.77 8.0 11.8 1.2 7.4 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC PF00098.23 EPE33094.1 - 0.83 9.9 3.1 2 8.6 3.1 1.7 1 1 0 1 1 1 0 Zinc knuckle Hid1 PF12722.7 EPE33094.1 - 6.5 4.7 7.3 8.6 4.3 7.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MUG113 PF13455.6 EPE33095.1 - 0.47 11.2 5.7 0.12 13.0 1.7 2.2 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 FmdE PF02663.14 EPE33095.1 - 1.3 9.0 3.1 2.8 8.0 3.1 1.5 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Ndc1_Nup PF09531.10 EPE33095.1 - 1.8 7.1 7.4 2.4 6.7 7.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ADH_N PF08240.12 EPE33096.1 - 9.3e-28 96.3 0.3 2.1e-27 95.1 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE33096.1 - 1.2e-27 96.5 0.4 2.8e-27 95.3 0.4 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE33096.1 - 2e-06 28.9 0.1 4e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EPE33096.1 - 0.0028 17.6 0.2 0.015 15.2 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.19 EPE33096.1 - 0.017 14.5 0.0 0.04 13.3 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EPE33096.1 - 0.047 13.9 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EPE33096.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EPE33096.1 - 0.12 12.9 0.2 0.24 11.8 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TPP_enzyme_N PF02776.18 EPE33097.1 - 2.9e-37 127.9 0.0 8.3e-37 126.4 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EPE33097.1 - 3.6e-19 69.1 0.0 8.2e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EPE33097.1 - 1.5e-10 40.9 0.0 3.9e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Cyclin PF08613.11 EPE33098.1 - 6.2e-45 153.5 0.0 1e-44 152.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin Peptidase_M24 PF00557.24 EPE33099.1 - 1.7e-55 187.9 0.1 2.3e-55 187.5 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EPE33099.1 - 4.4e-24 84.6 0.0 9.1e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Sulfatase PF00884.23 EPE33100.1 - 2.4e-17 63.3 0.1 4.3e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EPE33100.1 - 4.3e-05 23.3 0.0 6.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EPE33100.1 - 0.012 14.3 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DHFR_1 PF00186.19 EPE33101.1 - 5.2e-34 117.3 0.0 8.7e-34 116.6 0.0 1.4 1 1 0 1 1 1 1 Dihydrofolate reductase DUF4181 PF13789.6 EPE33103.1 - 0.02 15.2 1.7 0.048 13.9 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) DUF2417 PF10329.9 EPE33103.1 - 0.07 12.6 2.2 0.12 11.8 2.2 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DUF4131 PF13567.6 EPE33103.1 - 0.32 10.6 2.6 0.54 9.9 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Cpn60_TCP1 PF00118.24 EPE33104.1 - 1.7e-147 492.1 8.7 1.9e-147 491.9 8.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HMG_box PF00505.19 EPE33105.1 - 7.2e-07 29.5 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EPE33105.1 - 0.015 15.9 0.0 0.035 14.7 0.0 1.6 1 0 0 1 1 1 0 HMG-box domain DUF155 PF02582.14 EPE33106.1 - 1.8e-53 181.3 0.4 2.9e-53 180.5 0.4 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 EPE33106.1 - 0.076 13.5 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF2854 PF11016.8 EPE33108.1 - 0.085 12.8 0.5 0.09 12.7 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) Glyco_hydro_61 PF03443.14 EPE33109.1 - 6e-68 228.8 0.7 6e-68 228.8 0.7 1.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 LPAM_1 PF08139.12 EPE33110.1 - 0.39 11.3 1.6 0.42 11.2 0.1 1.9 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site UPF0121 PF03661.13 EPE33113.1 - 7.4e-32 110.7 2.8 9.7e-32 110.3 2.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) CaATP_NAI PF12515.8 EPE33113.1 - 0.023 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain MFS_1 PF07690.16 EPE33114.1 - 7.4e-32 110.6 37.1 7.4e-32 110.6 37.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2970 PF11174.8 EPE33114.1 - 2.6 7.9 5.4 25 4.8 3.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Cupin_2 PF07883.11 EPE33115.1 - 0.057 13.1 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Septin PF00735.18 EPE33117.1 - 3.5e-120 400.5 0.1 3.5e-120 400.5 0.1 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EPE33117.1 - 8e-08 32.4 1.3 1.2e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EPE33117.1 - 5.1e-05 22.9 1.9 0.0038 16.8 0.0 3.1 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EPE33117.1 - 5.5e-05 23.1 1.8 0.0025 17.7 0.7 3.2 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EPE33117.1 - 0.00024 21.6 2.1 0.035 14.6 0.0 2.8 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.6 EPE33117.1 - 0.0019 18.6 0.0 0.0064 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AIG1 PF04548.16 EPE33117.1 - 0.0032 16.8 1.1 0.0094 15.3 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 EPE33117.1 - 0.0048 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EPE33117.1 - 0.015 15.6 1.6 0.067 13.5 0.0 2.8 3 1 0 3 3 3 0 AAA domain Ras PF00071.22 EPE33117.1 - 0.016 14.8 0.4 0.069 12.7 0.0 2.3 2 1 0 2 2 2 0 Ras family AAA_29 PF13555.6 EPE33117.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EPE33117.1 - 0.057 13.1 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EPE33117.1 - 0.066 12.6 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 EPE33117.1 - 0.17 12.3 0.2 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 EPE33117.1 - 0.17 11.9 7.6 1.1 9.3 0.0 3.6 3 1 0 3 3 3 0 Dynamin family DUF87 PF01935.17 EPE33117.1 - 0.39 10.8 3.2 6.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 EPE33117.1 - 0.64 9.8 5.3 18 5.0 0.0 3.7 4 1 0 4 4 4 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.15 EPE33117.1 - 0.8 9.2 7.5 1.4 8.4 7.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 EPE33117.1 - 2.7 7.0 8.6 5.3 6.0 8.6 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DLH PF01738.18 EPE33118.1 - 5.4e-27 94.7 0.0 6.3e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EPE33118.1 - 0.015 14.9 0.0 0.037 13.7 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.11 EPE33118.1 - 0.09 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) RNA_pol_I_TF PF04090.12 EPE33119.1 - 1e-09 38.2 0.0 2.6e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor DUF2620 PF10941.8 EPE33120.1 - 0.22 11.7 0.7 1.6 8.9 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function DUF2620 FliC_SP PF12613.8 EPE33120.1 - 0.58 10.7 0.1 0.58 10.7 0.1 3.3 3 0 0 3 3 3 0 Flagellin structural protein UDPGT PF00201.18 EPE33121.1 - 2.3e-14 53.1 0.0 5.3e-14 51.9 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EPE33121.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 EPE33121.1 - 0.0027 17.8 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Ubiq_cyt_C_chap PF03981.12 EPE33122.1 - 8.9e-36 123.1 0.7 1.3e-35 122.6 0.7 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Exo70 PF03081.15 EPE33123.1 - 4.9e-85 285.8 0.0 1.6e-84 284.2 0.0 1.8 2 0 0 2 2 2 1 Exo70 exocyst complex subunit DUF2203 PF09969.9 EPE33123.1 - 0.54 11.0 2.2 2.9 8.6 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) PLA2_B PF01735.18 EPE33124.1 - 2.1e-24 85.8 0.0 7.2e-24 84.1 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain DSPc PF00782.20 EPE33125.1 - 1e-09 38.3 0.0 2.2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EPE33125.1 - 7.1e-05 22.5 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EPE33125.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EPE33125.1 - 0.21 11.7 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Hydrolase_4 PF12146.8 EPE33126.1 - 5.2e-09 35.7 0.2 1.1e-08 34.6 0.2 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIP PF03583.14 EPE33126.1 - 2.5e-06 27.0 2.6 2e-05 24.0 2.6 2.1 1 1 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 EPE33126.1 - 0.00024 20.6 0.3 0.58 9.6 0.1 2.7 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EPE33126.1 - 0.0006 19.5 0.1 0.0047 16.6 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EPE33126.1 - 0.0053 15.7 0.1 0.0099 14.8 0.1 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 EPE33126.1 - 0.0076 15.8 0.1 1.3 8.5 0.1 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EPE33126.1 - 0.027 14.4 0.0 0.07 13.0 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 EPE33126.1 - 0.093 12.6 0.0 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Palmitoyl protein thioesterase HATPase_c PF02518.26 EPE33127.1 - 3.5e-23 82.2 0.1 1.2e-22 80.5 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPE33127.1 - 1.3e-19 70.5 0.2 2.9e-17 62.9 0.1 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 EPE33127.1 - 1.8e-12 47.1 0.0 4.5e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 EPE33127.1 - 1.9e-06 28.2 0.0 8.3e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 GAF domain DUF2375 PF09558.10 EPE33127.1 - 0.26 11.3 1.0 5.1 7.2 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2375) Fungal_trans PF04082.18 EPE33128.1 - 3.1e-11 42.8 0.1 4.7e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE33128.1 - 4e-06 26.9 14.2 6.5e-06 26.2 14.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG27 PF09451.10 EPE33129.1 - 1.7e-96 323.1 0.0 2e-96 322.9 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EPE33129.1 - 0.00014 22.0 0.5 0.021 14.9 0.1 2.9 3 0 0 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat HLH PF00010.26 EPE33130.1 - 2.9e-11 43.2 0.8 2e-10 40.5 0.3 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain RicinB_lectin_2 PF14200.6 EPE33130.1 - 3.5e-06 27.7 4.3 0.33 11.7 0.3 3.9 2 1 2 4 4 4 4 Ricin-type beta-trefoil lectin domain-like DAO PF01266.24 EPE33131.1 - 2e-53 182.3 0.0 2.6e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fungal_trans PF04082.18 EPE33131.1 - 2e-11 43.5 1.2 4.4e-11 42.3 1.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE33131.1 - 2.7e-07 30.6 9.5 6e-07 29.5 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_8 PF13450.6 EPE33131.1 - 0.0042 17.3 0.1 0.012 15.8 0.1 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE33131.1 - 0.044 12.9 0.2 0.18 10.9 0.2 1.9 1 1 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 EPE33131.1 - 0.067 12.0 0.2 0.26 10.1 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 EPE33131.1 - 0.16 11.2 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 EPE33131.1 - 0.2 10.8 0.0 0.82 8.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Hepatitis_core PF00906.20 EPE33132.1 - 0.04 13.5 8.6 0.05 13.1 8.6 1.2 1 0 0 1 1 1 0 Hepatitis core antigen CwsA PF10814.8 EPE33132.1 - 0.076 13.2 0.5 0.076 13.2 0.5 2.1 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA ABA_WDS PF02496.16 EPE33132.1 - 0.1 13.1 0.4 0.1 13.1 0.4 2.5 2 1 0 2 2 2 0 ABA/WDS induced protein HSP20 PF00011.21 EPE33133.1 - 3.6e-08 33.5 0.0 1.6e-07 31.4 0.0 1.9 1 1 1 2 2 2 1 Hsp20/alpha crystallin family DUF2379 PF09543.10 EPE33133.1 - 0.14 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) F-box-like PF12937.7 EPE33134.1 - 0.00062 19.6 0.9 0.0022 17.9 0.9 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EPE33134.1 - 0.034 14.6 7.1 1.3 9.6 0.0 4.9 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EPE33134.1 - 0.07 13.2 10.5 25 5.2 0.0 6.2 6 0 0 6 6 6 0 Leucine Rich repeat zf-H2C2_2 PF13465.6 EPE33135.1 - 8.8e-06 25.9 9.1 4.4e-05 23.7 1.5 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EPE33135.1 - 6.6e-05 23.1 13.7 0.014 15.8 5.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE33135.1 - 0.00015 22.3 12.5 0.012 16.4 1.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE33135.1 - 0.95 9.8 9.0 4.9 7.6 1.7 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding MCM_OB PF17207.3 EPE33136.1 - 0.03 14.2 0.1 0.045 13.6 0.1 1.3 1 0 0 1 1 1 0 MCM OB domain TMEM51 PF15345.6 EPE33136.1 - 0.12 12.2 3.3 0.15 11.8 3.3 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 Macoilin PF09726.9 EPE33136.1 - 2.2 6.7 7.1 2.3 6.7 7.1 1.0 1 0 0 1 1 1 0 Macoilin family Hexapep PF00132.24 EPE33137.1 - 9.6e-08 31.5 6.0 0.00089 18.9 1.6 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EPE33137.1 - 0.00019 21.8 0.0 0.00038 20.8 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 EPE33137.1 - 0.005 15.8 0.3 0.0071 15.3 0.3 1.2 1 0 0 1 1 1 1 L-fucokinase NTP_transferase PF00483.23 EPE33137.1 - 0.0052 16.4 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 EPE33137.1 - 0.015 13.5 0.2 0.022 12.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) TAFA PF12020.8 EPE33137.1 - 1.5 9.3 4.9 0.53 10.8 1.6 1.9 2 1 0 2 2 2 0 TAFA family SRP19 PF01922.17 EPE33139.1 - 1.1e-32 112.8 0.0 1.8e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein GET2 PF08690.10 EPE33139.1 - 3.9 7.0 4.0 2.1 7.9 1.2 1.7 2 0 0 2 2 2 0 GET complex subunit GET2 DUF3446 PF11928.8 EPE33140.1 - 8.2 6.8 14.3 11 6.4 14.3 1.2 1 0 0 1 1 1 0 Early growth response N-terminal domain HIRA_B PF09453.10 EPE33141.1 - 0.32 10.9 0.8 0.64 9.9 0.8 1.5 1 0 0 1 1 1 0 HIRA B motif Slu7 PF11708.8 EPE33141.1 - 0.37 10.5 14.2 0.5 10.1 8.3 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor Cytomega_UL84 PF06284.11 EPE33141.1 - 0.52 8.7 1.5 0.61 8.5 1.5 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF3216 PF11505.8 EPE33141.1 - 0.63 10.3 9.1 1.9 8.8 6.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3216) DUF3464 PF11947.8 EPE33141.1 - 1.9 8.3 6.0 0.47 10.2 3.1 1.5 1 1 1 2 2 2 0 Photosynthesis affected mutant 68 MFS_1 PF07690.16 EPE33143.1 - 2.7e-41 141.7 35.6 4.3e-40 137.7 36.0 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE33143.1 - 1.1e-13 50.9 6.5 1.1e-13 50.9 6.5 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EPE33143.1 - 2.8e-06 26.9 1.2 2.8e-06 26.9 1.2 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Mobilization_B PF17511.2 EPE33143.1 - 0.1 13.0 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 Mobilization protein B Prefoldin_2 PF01920.20 EPE33144.1 - 1.8e-25 89.0 7.2 2.4e-25 88.5 7.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit MerR-DNA-bind PF09278.11 EPE33144.1 - 0.013 16.0 1.0 0.013 16.0 1.0 1.8 2 0 0 2 2 2 0 MerR, DNA binding PI3K_P85_iSH2 PF16454.5 EPE33144.1 - 0.02 14.5 6.4 0.043 13.4 6.4 1.5 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DivIC PF04977.15 EPE33144.1 - 0.026 14.3 10.1 0.088 12.6 0.7 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF1690 PF07956.11 EPE33144.1 - 0.22 11.9 8.8 0.22 11.9 7.7 1.6 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) APG6_N PF17675.1 EPE33144.1 - 0.22 12.0 14.7 0.62 10.6 1.0 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DNA_primase_lrg PF04104.14 EPE33144.1 - 0.24 10.7 1.8 0.26 10.6 0.2 1.7 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit Spc24 PF08286.11 EPE33144.1 - 0.37 11.0 9.6 0.18 12.1 1.0 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TBCA PF02970.16 EPE33144.1 - 0.4 11.0 11.3 1.4 9.3 11.3 2.0 1 1 0 1 1 1 0 Tubulin binding cofactor A DUF1664 PF07889.12 EPE33144.1 - 0.63 10.1 0.1 0.63 10.1 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) EMP24_GP25L PF01105.24 EPE33144.1 - 0.76 9.7 5.0 1.5 8.8 5.0 1.6 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD p450 PF00067.22 EPE33145.1 - 1.8e-68 231.4 0.0 2.2e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CVNH PF08881.10 EPE33146.1 - 9.7e-13 48.7 0.0 1.2e-12 48.4 0.0 1.1 1 0 0 1 1 1 1 CVNH domain AA_permease_2 PF13520.6 EPE33147.1 - 5.3e-65 219.9 49.3 6.6e-65 219.6 49.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE33147.1 - 1.1e-10 40.8 40.0 1.8e-10 40.0 40.0 1.4 1 1 0 1 1 1 1 Amino acid permease PAGK PF15284.6 EPE33147.1 - 0.22 11.5 0.1 0.22 11.5 0.1 2.6 3 0 0 3 3 3 0 Phage-encoded virulence factor Metallophos PF00149.28 EPE33148.1 - 1.3e-11 45.5 0.7 1.9e-11 44.9 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ANAPC10 PF03256.16 EPE33149.1 - 1.7e-50 171.2 0.0 2.4e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Gly_acyl_tr_C PF08444.10 EPE33150.1 - 0.001 19.3 0.1 0.0012 19.0 0.1 1.2 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region CdiI PF07262.11 EPE33150.1 - 0.057 13.2 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 CDI immunity protein DUF1127 PF06568.11 EPE33150.1 - 0.066 13.0 3.8 0.099 12.4 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) Aspzincin_M35 PF14521.6 EPE33152.1 - 0.00016 22.2 1.9 0.00035 21.2 1.9 1.6 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 EPE33152.1 - 0.0025 16.8 0.9 0.0036 16.2 0.9 1.3 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.6 EPE33152.1 - 0.0052 16.4 7.8 0.56 9.7 1.1 2.7 2 1 0 2 2 2 2 Putative peptidase family DUF3347 PF11827.8 EPE33154.1 - 0.034 14.3 0.2 3.7 7.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Cas_Cas5d PF09704.10 EPE33154.1 - 0.068 13.0 0.1 0.094 12.6 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas5) Vps51 PF08700.11 EPE33154.1 - 0.17 12.0 1.3 0.42 10.7 0.5 2.1 1 1 0 1 1 1 0 Vps51/Vps67 FAD_binding_4 PF01565.23 EPE33156.1 - 3.4e-22 78.7 1.7 6.9e-22 77.7 1.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE33156.1 - 1.2e-11 44.5 0.0 2.4e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like YjbF PF11102.8 EPE33156.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF zf-CCCH PF00642.24 EPE33157.1 - 0.031 14.2 1.3 0.031 14.2 1.3 3.3 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EPE33157.1 - 0.083 13.0 0.3 0.083 13.0 0.3 3.5 4 0 0 4 4 4 0 Zinc finger domain Torus PF16131.5 EPE33157.1 - 0.13 13.0 0.5 0.13 13.0 0.5 2.4 1 1 0 2 2 2 0 Torus domain Toxin_21 PF08091.11 EPE33157.1 - 2 8.4 7.7 0.89 9.5 1.6 2.5 2 0 0 2 2 2 0 Spider insecticidal peptide SET PF00856.28 EPE33158.1 - 1.4e-12 48.4 0.0 2.7e-12 47.4 0.0 1.5 1 1 0 1 1 1 1 SET domain CTU2 PF10288.9 EPE33158.1 - 0.29 11.4 1.9 5.5 7.3 0.0 2.7 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 Asp_protease_2 PF13650.6 EPE33160.1 - 0.15 12.7 0.0 0.69 10.6 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease DUF2723 PF11028.8 EPE33161.1 - 0.013 15.4 3.0 0.021 14.7 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) Ala_racemase_N PF01168.20 EPE33164.1 - 1.4e-22 80.5 0.0 1.6e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HALZ PF02183.18 EPE33164.1 - 0.017 15.3 1.8 0.033 14.4 1.8 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper MS_channel PF00924.18 EPE33165.1 - 2.2e-16 60.0 1.9 5.3e-16 58.8 1.9 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EPE33165.1 - 0.0083 15.6 0.1 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EPE33165.1 - 0.011 16.2 0.1 0.03 14.8 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 EPE33165.1 - 0.03 14.2 0.0 0.091 12.7 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 EPE33165.1 - 0.087 12.4 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 EF hand Zip PF02535.22 EPE33167.1 - 7e-42 143.8 20.1 7e-42 143.8 20.1 2.2 2 1 0 2 2 2 1 ZIP Zinc transporter HRXXH PF13933.6 EPE33168.1 - 1.1e-96 323.1 0.1 1.1e-96 323.1 0.1 1.5 2 0 0 2 2 2 1 Putative peptidase family IMUP PF15761.5 EPE33168.1 - 0.083 13.6 4.1 0.16 12.7 4.1 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein SSP160 PF06933.11 EPE33168.1 - 6.1 4.9 16.8 8.9 4.4 16.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 LSM PF01423.22 EPE33169.1 - 3.8e-12 45.7 0.0 4.9e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain ECH_2 PF16113.5 EPE33170.1 - 1.3e-126 422.7 0.0 1.9e-126 422.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EPE33170.1 - 7.1e-26 91.0 0.7 1.6e-23 83.3 0.0 2.5 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase DUF5071 PF16804.5 EPE33170.1 - 0.12 12.7 0.0 0.39 11.0 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5071) GATA PF00320.27 EPE33172.1 - 2.9e-06 26.8 5.0 0.016 14.8 1.1 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF2543 PF10820.8 EPE33172.1 - 0.084 13.1 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) Rep_fac-A_3 PF08661.11 EPE33173.1 - 6.3e-28 97.2 0.0 7e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ribosomal_L4 PF00573.22 EPE33174.1 - 6.8e-44 149.8 0.0 9.2e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family RNA_pol_Rpb2_6 PF00562.28 EPE33174.1 - 0.17 10.9 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 PBP PF01161.20 EPE33175.1 - 2.4e-10 40.8 0.0 4.3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PH PF00169.29 EPE33176.1 - 1.1e-23 83.7 0.8 2e-12 47.5 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 EPE33176.1 - 2.5e-08 34.3 0.6 0.014 15.8 0.1 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 EPE33176.1 - 3.6e-08 33.8 0.6 0.0031 17.9 0.2 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 EPE33176.1 - 3.2e-05 24.1 0.1 6.3e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Myosin_TH1 PF06017.13 EPE33176.1 - 0.036 13.8 0.1 0.058 13.1 0.1 1.3 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding PH_13 PF16652.5 EPE33176.1 - 0.1 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain GTP_EFTU PF00009.27 EPE33177.1 - 7.1e-58 195.4 0.0 1.3e-57 194.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EPE33177.1 - 4.1e-16 58.8 0.0 1.4e-15 57.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EPE33177.1 - 6.3e-09 36.1 0.0 1.7e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EPE33177.1 - 1.9e-06 27.8 0.0 4.9e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EPE33177.1 - 0.00041 20.1 0.0 0.0033 17.2 0.0 2.6 2 1 0 2 2 2 1 Elongation factor G, domain IV D123 PF07065.14 EPE33177.1 - 0.016 14.3 0.2 0.028 13.6 0.2 1.3 1 0 0 1 1 1 0 D123 MMR_HSR1 PF01926.23 EPE33177.1 - 0.033 14.3 0.0 0.089 12.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase MPM1 PF17234.2 EPE33177.1 - 0.2 11.9 1.5 0.25 11.6 0.1 1.8 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Helo_like_N PF17111.5 EPE33178.1 - 5.7e-07 29.1 0.1 1.3e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Cofilin_ADF PF00241.20 EPE33183.1 - 0.009 15.8 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cupin_1 PF00190.22 EPE33184.1 - 1.4e-34 118.9 0.0 5.2e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EPE33184.1 - 1.2e-23 82.6 0.1 2.9e-12 46.1 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EPE33184.1 - 1.2e-07 31.3 0.0 0.0067 16.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 EPE33184.1 - 2.4e-05 24.3 0.0 0.00045 20.1 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase AraC_binding PF02311.19 EPE33184.1 - 0.00014 21.8 0.1 0.0052 16.7 0.0 2.5 3 0 0 3 3 3 1 AraC-like ligand binding domain 3-HAO PF06052.12 EPE33184.1 - 0.003 17.2 0.0 0.027 14.1 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase CENP-C_C PF11699.8 EPE33184.1 - 0.2 11.9 0.0 0.88 9.8 0.0 1.9 2 0 0 2 2 2 0 Mif2/CENP-C like Tom22 PF04281.13 EPE33185.1 - 6.6e-49 165.2 0.5 1.2e-48 164.4 0.5 1.4 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Bestrophin PF01062.21 EPE33185.1 - 3.6e-43 148.1 0.0 3.2e-21 76.0 0.0 2.2 1 1 1 2 2 2 2 Bestrophin, RFP-TM, chloride channel Pol_alpha_B_N PF08418.10 EPE33186.1 - 4.5e-79 265.9 0.6 5.7e-79 265.6 0.6 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 EPE33186.1 - 1.2e-37 129.3 0.0 1.7e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B TMV_coat PF00721.21 EPE33186.1 - 0.16 11.8 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Virus coat protein (TMV like) MFAP1 PF06991.11 EPE33187.1 - 6.2e-74 248.5 32.4 6.2e-74 248.5 32.4 2.1 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing Cwf_Cwc_15 PF04889.12 EPE33187.1 - 0.53 10.0 49.9 0.077 12.7 30.4 2.3 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF3365 PF11845.8 EPE33187.1 - 2.5 8.4 7.8 5.5 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) Alb1 PF09135.11 EPE33188.1 - 2.3e-29 102.3 13.4 2.3e-29 102.3 13.4 1.7 2 0 0 2 2 2 1 Alb1 TMCO5 PF14992.6 EPE33188.1 - 0.2 11.2 2.9 0.25 10.9 2.9 1.1 1 0 0 1 1 1 0 TMCO5 family UCH PF00443.29 EPE33189.1 - 5.8e-37 127.6 0.0 7.9e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPE33189.1 - 3.8e-06 26.7 0.1 1.5e-05 24.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase COMPASS-Shg1 PF05205.12 EPE33190.1 - 5.9e-23 81.5 0.1 5.9e-23 81.5 0.1 2.1 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 IF-2B PF01008.17 EPE33192.1 - 1.9e-75 253.7 0.0 2.4e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Ribosomal_S18 PF01084.20 EPE33192.1 - 0.12 12.6 0.1 0.57 10.4 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein S18 FleQ PF06490.11 EPE33192.1 - 0.16 12.4 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Aspzincin_M35 PF14521.6 EPE33194.1 - 0.00061 20.4 0.0 0.0014 19.2 0.0 1.6 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Glyco_transf_28 PF03033.20 EPE33196.1 - 1.4e-22 80.2 0.0 2.8e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EPE33196.1 - 7.2e-05 21.8 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EPE33196.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain VPS13_C PF16909.5 EPE33196.1 - 1.8 8.3 4.8 3.2 7.5 0.6 2.3 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal PGAP1 PF07819.13 EPE33197.1 - 0.00017 21.4 0.0 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EPE33197.1 - 0.0004 21.0 0.4 0.00072 20.2 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE33197.1 - 0.00076 18.8 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EPE33197.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF2974 PF11187.8 EPE33197.1 - 0.19 11.2 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Fungal_trans_2 PF11951.8 EPE33198.1 - 2.9e-08 33.0 0.2 4.3e-08 32.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE33198.1 - 0.013 15.6 1.4 0.028 14.5 1.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3_C PF01915.22 EPE33200.1 - 1.3e-49 168.9 0.0 2.1e-49 168.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE33200.1 - 2.1e-39 135.8 0.0 3.5e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE33200.1 - 6.6e-19 67.8 0.1 1.2e-18 67.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Carb_anhydrase PF00194.21 EPE33201.1 - 6e-30 104.6 0.0 1.1e-29 103.7 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF4211 PF13926.6 EPE33202.1 - 4.1e-41 140.4 0.1 1.1e-40 139.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) CaM_bdg_C0 PF10562.9 EPE33202.1 - 0.1 12.7 4.0 0.25 11.4 4.0 1.7 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit BTB PF00651.31 EPE33203.1 - 1.2e-07 31.9 0.0 2.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB_2 PF02214.22 EPE33205.1 - 3.3e-07 30.5 0.0 0.0063 16.8 0.0 2.6 3 0 0 3 3 3 2 BTB/POZ domain COesterase PF00135.28 EPE33206.1 - 2.2e-85 287.5 0.1 2.8e-77 260.8 0.1 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE33206.1 - 3.5e-11 43.4 0.0 6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold NDT80_PhoG PF05224.12 EPE33208.1 - 0.052 13.8 0.6 0.068 13.4 0.6 1.1 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family Sugar_tr PF00083.24 EPE33209.1 - 4.5e-79 266.4 28.3 5.3e-79 266.2 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE33209.1 - 2.2e-17 63.1 42.8 3.1e-10 39.5 20.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-MYND PF01753.18 EPE33210.1 - 6.4e-10 39.0 14.2 1.1e-09 38.3 14.2 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EPE33210.1 - 0.0051 16.9 9.8 0.0092 16.1 9.8 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 EPE33210.1 - 0.63 10.4 14.1 2.9 8.3 13.8 2.1 1 1 1 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding PADR1 PF08063.12 EPE33210.1 - 4.5 7.1 10.2 1.1 9.0 3.7 2.3 2 0 0 2 2 2 0 PADR1 (NUC008) domain Dak1 PF02733.17 EPE33212.1 - 5.9e-103 344.0 5.3 8.5e-103 343.5 5.3 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EPE33212.1 - 1.3e-47 161.9 1.5 2.7e-47 160.9 1.5 1.6 1 0 0 1 1 1 1 DAK2 domain DUF5635 PF18685.1 EPE33212.1 - 0.028 14.3 0.0 0.076 13.0 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5635) EXOSC1 PF10447.9 EPE33213.1 - 2.2e-20 73.3 3.5 9.3e-14 52.0 0.3 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EPE33213.1 - 7.7e-11 41.6 0.0 1.6e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region YojJ PF10372.9 EPE33214.1 - 0.014 15.4 1.8 0.023 14.8 1.8 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus UPF0242 PF06785.11 EPE33214.1 - 0.59 10.2 9.2 0.6 10.2 9.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 EPE33214.1 - 1.7 7.9 7.9 1.9 7.8 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2058 PF09831.9 EPE33214.1 - 5.5 7.1 16.2 6.3 6.9 16.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) RhoGAP PF00620.27 EPE33216.1 - 1.1e-12 48.0 0.0 3.3e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain PKcGMP_CC PF16808.5 EPE33216.1 - 0.01 15.7 1.3 0.028 14.3 1.3 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase XLF PF09302.11 EPE33216.1 - 0.011 15.9 0.2 0.026 14.7 0.2 1.6 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Bap31_Bap29_C PF18035.1 EPE33216.1 - 3.7 7.6 6.2 20 5.3 3.9 2.7 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain CBS PF00571.28 EPE33217.1 - 5.4e-22 78.0 9.1 1.9e-10 41.0 0.3 4.2 4 0 0 4 4 4 3 CBS domain ISET-FN3_linker PF16625.5 EPE33218.1 - 0.17 12.4 0.1 0.36 11.4 0.1 1.5 1 0 0 1 1 1 0 Unstructured linking region I-set and fnIII on Brother of CDO Arm PF00514.23 EPE33219.1 - 8.7e-72 235.2 33.6 3.9e-13 49.0 0.2 11.3 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EPE33219.1 - 1.9e-19 69.7 14.1 5.2e-06 26.8 0.2 7.9 6 1 2 8 8 7 5 HEAT-like repeat HEAT_2 PF13646.6 EPE33219.1 - 6.3e-17 61.8 10.7 0.00071 19.9 0.2 6.9 3 1 4 7 7 7 5 HEAT repeats HEAT PF02985.22 EPE33219.1 - 3.4e-15 54.8 16.9 0.053 13.8 0.3 8.7 10 0 0 10 10 9 4 HEAT repeat Adaptin_N PF01602.20 EPE33219.1 - 7.4e-13 47.9 8.2 1.9e-08 33.3 0.4 2.7 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 EPE33219.1 - 2.8e-10 40.1 7.7 2.2e-05 24.1 4.2 2.9 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.14 EPE33219.1 - 1.8e-09 37.3 3.3 0.00015 21.2 2.0 3.7 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.12 EPE33219.1 - 2.3e-09 36.0 0.6 4.8e-09 34.9 0.3 1.6 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Cnd1 PF12717.7 EPE33219.1 - 2.7e-05 24.3 9.9 0.02 14.9 0.2 5.2 1 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 EPE33219.1 - 0.00015 21.9 3.5 3.1 7.9 0.3 5.1 2 1 6 8 8 8 1 V-ATPase subunit H DUF3361 PF11841.8 EPE33219.1 - 0.00017 21.6 7.5 2.2 8.2 0.0 4.4 2 1 2 4 4 4 2 Domain of unknown function (DUF3361) DUF5578 PF17741.1 EPE33219.1 - 0.00042 19.8 7.5 0.71 9.2 0.0 5.0 2 1 3 6 6 6 2 Family of unknown function (DUF5578) HEAT_PBS PF03130.16 EPE33219.1 - 0.002 18.6 8.7 5.4 8.0 1.2 6.7 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 EPE33219.1 - 0.0074 16.9 0.4 0.66 10.6 0.1 3.8 3 1 2 5 5 5 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 EPE33219.1 - 0.013 14.7 9.9 1.8 7.6 0.1 4.4 4 2 1 5 5 5 0 Interferon-related developmental regulator (IFRD) Vpu PF00558.19 EPE33219.1 - 0.017 14.8 0.9 0.053 13.3 0.3 2.1 2 0 0 2 2 2 0 Vpu protein UNC45-central PF11701.8 EPE33219.1 - 0.066 13.2 5.1 3.8 7.5 0.2 3.6 3 1 0 4 4 4 0 Myosin-binding striated muscle assembly central Atx10homo_assoc PF09759.9 EPE33219.1 - 0.3 11.2 8.7 3.9 7.6 0.1 4.5 4 2 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain IBB PF01749.20 EPE33219.1 - 7.5 7.1 5.7 39 4.8 0.1 3.9 4 1 1 5 5 4 0 Importin beta binding domain Peptidase_S24 PF00717.23 EPE33220.1 - 6.7e-09 35.6 0.1 1.1e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EPE33220.1 - 4.7e-05 23.2 0.0 0.0031 17.3 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 IF3_C PF00707.22 EPE33221.1 - 3.1e-05 23.9 1.3 6.9e-05 22.7 1.3 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain RcpC PF16976.5 EPE33221.1 - 0.0015 18.5 1.6 0.0038 17.2 0.1 2.2 2 0 0 2 2 2 1 Flp pilus assembly protein RcpC/CpaB mIF3 PF14877.6 EPE33221.1 - 0.0038 16.9 8.8 0.048 13.3 7.9 2.6 1 1 1 2 2 2 1 Mitochondrial translation initiation factor IF3_N PF05198.16 EPE33221.1 - 0.0057 16.9 3.3 0.026 14.8 3.3 2.1 1 1 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain SMBP PF16785.5 EPE33221.1 - 0.15 12.3 5.2 0.071 13.3 2.0 2.0 2 0 0 2 2 2 0 Small metal-binding protein ATP_bind_1 PF03029.17 EPE33221.1 - 0.16 11.7 0.2 0.25 11.1 0.2 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein TssO PF17561.2 EPE33222.1 - 0.015 15.4 3.2 0.027 14.6 1.8 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssO CCDC85 PF10226.9 EPE33222.1 - 1.8 8.2 11.2 0.057 13.1 1.4 2.6 2 1 0 2 2 2 0 CCDC85 family HSP70 PF00012.20 EPE33223.1 - 4e-11 41.8 1.2 4.7e-09 35.0 0.3 2.7 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 EPE33223.1 - 0.00038 19.4 0.1 0.0061 15.4 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein WSC PF01822.19 EPE33224.1 - 2.9e-55 184.4 55.4 3e-19 69.0 11.8 4.2 4 0 0 4 4 4 3 WSC domain DUF3494 PF11999.8 EPE33224.1 - 3.1e-44 151.1 18.1 3.1e-44 151.1 18.1 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF3494) HeLo PF14479.6 EPE33225.1 - 1.6e-07 31.4 1.6 0.015 15.2 0.8 2.6 1 1 1 2 2 2 2 Prion-inhibition and propagation Pkinase_fungal PF17667.1 EPE33225.1 - 0.096 11.4 0.1 0.096 11.4 0.1 1.7 2 0 0 2 2 2 0 Fungal protein kinase Malic_M PF03949.15 EPE33226.1 - 2.1e-93 312.3 0.1 2.9e-93 311.9 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EPE33226.1 - 9e-69 230.9 0.0 1.6e-68 230.1 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain His_Phos_1 PF00300.22 EPE33227.1 - 2.5e-17 63.2 0.0 3.9e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NUDIX PF00293.28 EPE33228.1 - 1.8e-10 41.0 0.0 2.3e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain zf-C2H2 PF00096.26 EPE33229.1 - 0.0018 18.6 32.9 0.02 15.4 2.0 5.2 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 EPE33229.1 - 0.62 10.4 6.3 4.4 7.7 3.7 3.2 1 1 0 2 2 2 0 C2H2-type zinc ribbon zf-met PF12874.7 EPE33229.1 - 1.7 9.1 13.5 0.76 10.3 1.1 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EPE33229.1 - 3.4 8.8 29.2 1.4 9.9 1.9 5.1 4 0 0 4 4 4 0 C2H2-type zinc finger Myb_DNA-bind_6 PF13921.6 EPE33230.1 - 3.5e-10 40.0 0.6 1.8e-09 37.7 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EPE33230.1 - 3.1e-09 36.9 0.2 8.1e-09 35.5 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ketoacyl-synt PF00109.26 EPE33230.1 - 6.1e-06 26.0 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Patatin PF01734.22 EPE33230.1 - 2.9e-05 24.3 0.0 9.8e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C2H2_jaz PF12171.8 EPE33230.1 - 0.0093 16.2 12.3 9.3 6.7 4.2 5.2 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding DUF3648 PF12364.8 EPE33230.1 - 0.086 13.1 1.5 0.25 11.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3648) zf-met PF12874.7 EPE33230.1 - 0.19 12.2 5.2 12 6.5 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EPE33230.1 - 0.29 11.7 29.8 2.1 9.0 0.2 6.9 6 0 0 6 6 6 0 Zinc finger, C2H2 type GFO_IDH_MocA PF01408.22 EPE33234.1 - 2.2e-17 64.0 0.1 3.6e-17 63.3 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EPE33234.1 - 0.00093 19.2 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF3425 PF11905.8 EPE33235.1 - 1.1e-16 61.0 0.1 2e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) AbiEii PF08843.11 EPE33237.1 - 0.00033 20.7 0.1 0.034 14.1 0.0 2.1 2 0 0 2 2 2 2 Nucleotidyl transferase AbiEii toxin, Type IV TA system CcmD PF04995.14 EPE33238.1 - 0.026 14.6 0.0 0.042 13.9 0.0 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF4129 PF13559.6 EPE33238.1 - 0.082 13.2 1.9 0.14 12.4 1.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4129) Aldo_ket_red PF00248.21 EPE33239.1 - 2.9e-47 161.3 0.0 3.6e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family YkyA PF10368.9 EPE33241.1 - 0.043 13.5 1.7 0.046 13.4 0.4 1.7 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Latarcin PF10279.9 EPE33241.1 - 0.049 14.0 0.3 0.097 13.1 0.3 1.5 1 0 0 1 1 1 0 Latarcin precursor NEMO PF11577.8 EPE33241.1 - 0.16 12.0 0.6 6.3 6.9 1.1 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO ADH_N PF08240.12 EPE33243.1 - 2.9e-09 36.8 0.1 1.1e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EPE33243.1 - 5.3e-08 34.0 0.0 1.1e-07 33.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPE33243.1 - 9.4e-07 28.9 0.0 1.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2272 PF10030.9 EPE33243.1 - 0.031 14.0 0.1 0.06 13.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) TPR_MLP1_2 PF07926.12 EPE33243.1 - 0.19 11.8 1.6 0.3 11.1 1.6 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein UPF0047 PF01894.17 EPE33244.1 - 9.5e-38 128.9 0.0 1.1e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 NUDIX_2 PF13869.6 EPE33245.1 - 1.2e-81 272.8 0.0 1.5e-81 272.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase NACHT PF05729.12 EPE33246.1 - 2.4e-11 43.8 0.0 6.4e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EPE33246.1 - 0.00028 21.3 0.3 0.0071 16.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 EPE33246.1 - 0.014 15.9 0.6 0.13 12.8 0.0 2.3 1 1 1 2 2 2 0 ABC transporter T2SSF PF00482.23 EPE33246.1 - 0.019 14.9 0.0 0.061 13.3 0.0 1.9 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F AAA_30 PF13604.6 EPE33246.1 - 0.056 13.2 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EPE33246.1 - 0.084 12.0 0.0 0.32 10.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_22 PF13401.6 EPE33246.1 - 0.16 12.2 0.0 0.53 10.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EPE33246.1 - 0.18 11.6 0.1 0.39 10.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cutinase PF01083.22 EPE33248.1 - 2.8e-49 167.5 3.6 3.3e-49 167.3 3.6 1.0 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 EPE33248.1 - 0.0041 16.8 0.0 0.0077 15.9 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EPE33248.1 - 0.055 13.3 0.1 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 EPE33248.1 - 0.059 13.2 0.5 0.073 12.9 0.5 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 EPE33248.1 - 0.07 13.0 0.1 0.07 12.9 0.1 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PE-PPE PF08237.11 EPE33248.1 - 0.1 12.1 0.2 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 PE-PPE domain DUF2974 PF11187.8 EPE33248.1 - 0.12 11.9 0.2 0.18 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3425 PF11905.8 EPE33249.1 - 1.7e-30 105.6 0.0 3.1e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) ARGLU PF15346.6 EPE33249.1 - 0.0063 16.4 4.8 0.0094 15.8 4.8 1.2 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 Peptidase_C2 PF00648.21 EPE33250.1 - 1.7e-55 188.2 3.0 4.4e-54 183.5 0.1 3.1 2 1 0 2 2 2 1 Calpain family cysteine protease CoaE PF01121.20 EPE33252.1 - 6.7e-42 143.2 0.0 1.9e-41 141.7 0.0 1.6 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 EPE33252.1 - 0.0046 17.1 0.0 0.038 14.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EPE33252.1 - 0.56 10.7 2.2 3.4 8.2 1.8 2.4 1 1 0 1 1 1 0 AAA domain COesterase PF00135.28 EPE33253.1 - 2.7e-103 346.6 0.1 8.6e-103 344.9 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE33253.1 - 0.00017 21.5 0.4 0.001 19.0 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Tim17 PF02466.19 EPE33255.1 - 8.5e-41 138.8 6.5 1.3e-40 138.2 6.5 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 EPE33255.1 - 0.061 13.5 1.1 0.061 13.5 1.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5518) Romo1 PF10247.9 EPE33255.1 - 5.2 7.5 14.2 0.45 10.9 2.3 3.4 2 1 2 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 ABA_WDS PF02496.16 EPE33255.1 - 8 7.0 6.6 1.1 9.7 1.3 2.3 2 1 0 2 2 2 0 ABA/WDS induced protein Wzy_C PF04932.15 EPE33256.1 - 0.15 11.7 3.8 6.6 6.4 1.6 2.2 1 1 1 2 2 2 0 O-Antigen ligase PS-DH PF14765.6 EPE33257.1 - 1.2e-62 211.9 0.0 1.7e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EPE33257.1 - 1.9e-59 200.6 0.0 4.9e-59 199.2 0.0 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EPE33257.1 - 8.7e-29 101.0 0.0 1.4e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.12 EPE33257.1 - 9.7e-19 68.0 0.0 4.5e-18 65.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EPE33257.1 - 1.2e-16 62.0 0.0 5.3e-16 59.9 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPE33257.1 - 7.4e-15 55.1 0.0 1.1e-13 51.3 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EPE33257.1 - 6.2e-13 48.6 0.0 2.2e-09 37.1 0.0 3.3 3 0 0 3 3 3 2 short chain dehydrogenase Methyltransf_23 PF13489.6 EPE33257.1 - 1.5e-11 44.5 0.0 6.9e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE33257.1 - 3e-11 43.9 0.0 1.4e-09 38.5 0.0 3.4 4 0 0 4 4 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE33257.1 - 1.9e-09 37.5 0.0 7.9e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE33257.1 - 5.6e-08 33.3 0.0 2.8e-07 31.1 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 EPE33257.1 - 3.7e-06 27.2 0.1 1.2e-05 25.6 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 EPE33257.1 - 0.00037 19.9 0.0 0.00084 18.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 EPE33257.1 - 0.00081 19.2 0.2 0.0016 18.3 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain T2SSM_b PF10741.9 EPE33257.1 - 0.0047 16.7 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M subtype b NodS PF05401.11 EPE33257.1 - 0.0066 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 EPE33257.1 - 0.014 15.1 0.0 0.17 11.6 0.0 2.5 2 1 0 2 2 2 0 Lysine methyltransferase ketoacyl-synt PF00109.26 EPE33258.1 - 2.7e-69 233.5 0.0 4.1e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EPE33258.1 - 8.8e-34 116.1 0.2 1.5e-33 115.3 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EPE33258.1 - 1.8e-24 86.3 0.0 3.5e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Acyl_transf_1 PF00698.21 EPE33258.1 - 2.5e-06 27.2 0.1 3.9e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Acyl transferase domain Thiolase_N PF00108.23 EPE33258.1 - 5.2e-06 26.0 0.2 8.4e-06 25.3 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EPE33258.1 - 0.0014 18.4 0.2 0.0028 17.5 0.2 1.5 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TRAM_LAG1_CLN8 PF03798.16 EPE33259.1 - 9.4e-18 64.7 4.2 1.1e-17 64.4 4.2 1.1 1 0 0 1 1 1 1 TLC domain MFS_1 PF07690.16 EPE33260.1 - 5.2e-37 127.6 49.3 7.4e-36 123.8 46.4 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPE33260.1 - 1e-17 63.8 20.3 2.1e-17 62.8 20.3 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPE33260.1 - 1.1e-14 54.2 16.6 1.1e-14 54.2 16.6 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EPE33260.1 - 0.001 17.5 1.9 0.001 17.5 1.9 2.9 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family CMS1 PF14617.6 EPE33262.1 - 5.9 6.1 7.3 13 5.0 7.3 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit BRF1 PF07741.13 EPE33262.1 - 7.9 6.9 10.8 0.57 10.6 1.3 3.1 3 0 0 3 3 3 0 Brf1-like TBP-binding domain DBINO PF13892.6 EPE33263.1 - 0.0036 17.6 4.5 0.0041 17.5 4.5 1.2 1 0 0 1 1 1 1 DNA-binding domain UNC-79 PF14776.6 EPE33263.1 - 0.16 10.7 0.5 0.18 10.5 0.5 1.0 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 DUF4398 PF14346.6 EPE33263.1 - 0.24 12.1 17.9 0.41 11.3 17.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) DUF5323 PF17257.2 EPE33263.1 - 0.42 10.5 5.0 0.8 9.6 5.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5323) Fez1 PF06818.15 EPE33264.1 - 4e-05 24.2 8.0 0.014 15.9 4.6 2.4 1 1 1 2 2 2 2 Fez1 Csm1_N PF18504.1 EPE33264.1 - 0.00025 21.3 9.9 0.27 11.6 1.8 3.8 2 1 2 4 4 4 2 Csm1 N-terminal domain CALCOCO1 PF07888.11 EPE33264.1 - 0.00046 19.2 14.8 0.049 12.5 0.4 2.1 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like Bacillus_HBL PF05791.11 EPE33264.1 - 0.0007 19.5 1.2 0.0014 18.5 0.9 1.7 2 0 0 2 2 1 1 Bacillus haemolytic enterotoxin (HBL) ATG16 PF08614.11 EPE33264.1 - 0.00093 19.5 16.6 0.0016 18.7 15.1 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EPE33264.1 - 0.0016 17.4 11.0 0.029 13.3 9.3 2.2 1 1 1 2 2 2 1 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 EPE33264.1 - 0.0021 18.0 17.5 0.0081 16.1 2.7 3.1 1 1 1 3 3 3 2 TATA element modulatory factor 1 DNA binding DUF4407 PF14362.6 EPE33264.1 - 0.0033 16.8 5.1 0.0054 16.1 5.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Lebercilin PF15619.6 EPE33264.1 - 0.0043 16.7 10.0 0.016 14.8 9.7 2.2 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease TPR_MLP1_2 PF07926.12 EPE33264.1 - 0.0082 16.2 19.5 0.017 15.2 10.0 2.6 2 1 1 3 3 2 1 TPR/MLP1/MLP2-like protein EzrA PF06160.12 EPE33264.1 - 0.0089 14.2 5.9 0.013 13.7 4.5 1.7 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA YabA PF06156.13 EPE33264.1 - 0.01 16.5 6.6 0.17 12.5 0.4 3.1 1 1 2 3 3 3 0 Initiation control protein YabA Herpes_U44 PF04533.13 EPE33264.1 - 0.013 15.1 0.6 0.028 14.0 0.3 1.5 1 1 0 1 1 1 0 Herpes virus U44 protein GAS PF13851.6 EPE33264.1 - 0.018 14.4 8.7 0.2 11.0 2.1 2.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Syntaxin PF00804.25 EPE33264.1 - 0.019 14.6 5.5 0.032 13.9 5.0 1.7 1 1 0 1 1 1 0 Syntaxin ADIP PF11559.8 EPE33264.1 - 0.021 14.9 9.7 0.028 14.5 2.4 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 EPE33264.1 - 0.023 13.8 13.1 0.03 13.4 12.5 1.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TSC22 PF01166.18 EPE33264.1 - 0.026 14.8 7.3 0.56 10.6 0.5 3.9 2 1 0 3 3 3 0 TSC-22/dip/bun family KASH_CCD PF14662.6 EPE33264.1 - 0.03 14.2 14.9 3.1 7.6 13.2 3.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF16 PF01519.16 EPE33264.1 - 0.038 14.5 1.8 0.36 11.4 0.5 2.8 1 1 2 3 3 3 0 Protein of unknown function DUF16 KLRAQ PF10205.9 EPE33264.1 - 0.044 14.0 2.6 0.51 10.6 0.1 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4201 PF13870.6 EPE33264.1 - 0.059 13.1 5.0 0.21 11.3 4.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF4665 PF15679.5 EPE33264.1 - 0.068 13.8 1.2 0.48 11.1 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) TMCO5 PF14992.6 EPE33264.1 - 0.1 12.2 5.1 0.14 11.7 5.1 1.2 1 0 0 1 1 1 0 TMCO5 family CC2-LZ PF16516.5 EPE33264.1 - 0.13 12.6 4.2 0.2 12.1 1.1 2.6 1 1 2 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Tup_N PF08581.10 EPE33264.1 - 0.2 12.0 2.6 0.98 9.8 0.4 3.2 2 1 1 3 3 2 0 Tup N-terminal DUF724 PF05266.14 EPE33264.1 - 0.2 11.4 10.7 4.2 7.2 10.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF724) SlyX PF04102.12 EPE33264.1 - 0.21 12.3 1.6 8.6 7.1 0.3 3.2 3 1 1 4 4 2 0 SlyX Fib_alpha PF08702.10 EPE33264.1 - 0.25 11.5 3.3 1.3 9.2 2.5 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Rootletin PF15035.6 EPE33264.1 - 0.27 11.2 5.7 0.56 10.2 5.7 1.6 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF3450 PF11932.8 EPE33264.1 - 0.34 10.2 9.2 3.1 7.0 4.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HMMR_C PF15908.5 EPE33264.1 - 0.39 11.0 4.6 3.5 7.9 0.6 3.3 1 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal UPF0242 PF06785.11 EPE33264.1 - 0.42 10.7 8.2 1.1 9.4 6.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 EPE33264.1 - 0.49 10.9 9.7 2.9 8.4 0.7 3.3 2 1 2 4 4 3 0 Cell division protein ZapB DUF1515 PF07439.11 EPE33264.1 - 0.51 10.4 2.4 8.1 6.5 0.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) AAA_13 PF13166.6 EPE33264.1 - 0.62 8.6 7.5 0.97 8.0 7.5 1.4 1 1 0 1 1 1 0 AAA domain Leu_zip PF15294.6 EPE33264.1 - 0.71 9.3 9.0 2.3 7.7 7.0 1.8 1 1 1 2 2 2 0 Leucine zipper CENP-F_leu_zip PF10473.9 EPE33264.1 - 0.73 9.9 14.9 7.6 6.6 1.9 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EPE33264.1 - 0.73 9.9 2.7 2.1 8.4 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.11 EPE33264.1 - 1.1 9.3 6.2 1.2 9.3 1.8 2.8 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4200 PF13863.6 EPE33264.1 - 1.3 9.5 5.6 3.2 8.2 4.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Shugoshin_N PF07558.11 EPE33264.1 - 1.7 8.6 5.9 3.2 7.7 2.3 3.2 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region PRKG1_interact PF15898.5 EPE33264.1 - 2.1 9.3 11.3 0.63 11.0 7.1 2.3 3 1 0 3 3 1 0 cGMP-dependent protein kinase interacting domain Wtap PF17098.5 EPE33264.1 - 2.1 8.3 12.7 2.8 7.8 1.7 3.6 1 1 3 4 4 4 0 WTAP/Mum2p family TMF_TATA_bd PF12325.8 EPE33264.1 - 2.3 8.5 17.8 3.4 7.9 3.0 3.4 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding CHDCT2 PF08074.11 EPE33264.1 - 2.3 8.3 4.8 4.1 7.6 0.7 2.3 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain DivIC PF04977.15 EPE33264.1 - 2.4 8.0 11.0 3.9 7.3 1.0 3.4 1 1 3 4 4 4 0 Septum formation initiator AATF-Che1 PF13339.6 EPE33264.1 - 3 8.5 7.8 8.4 7.1 7.8 2.0 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor BRE1 PF08647.11 EPE33264.1 - 4.8 7.3 12.8 5 7.3 6.8 3.0 2 1 1 3 3 2 0 BRE1 E3 ubiquitin ligase ABC_tran_CTD PF16326.5 EPE33264.1 - 8.6 6.7 8.6 2.4 8.5 1.4 2.9 2 1 1 3 3 2 0 ABC transporter C-terminal domain APG6_N PF17675.1 EPE33264.1 - 9.4 6.8 17.1 3.4 8.2 3.8 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region Cauli_VI PF01693.16 EPE33267.1 - 2.7e-23 82.0 3.4 9.1e-11 41.9 0.0 2.2 2 0 0 2 2 2 2 Caulimovirus viroplasmin HycH PF07450.11 EPE33267.1 - 0.02 15.3 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH GBP_C PF02841.14 EPE33268.1 - 0.1 12.0 3.4 0.14 11.6 3.4 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain SET PF00856.28 EPE33269.1 - 4.3e-07 30.5 0.0 7.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 SET domain IFT20 PF14931.6 EPE33269.1 - 0.028 14.6 0.6 0.076 13.2 0.4 1.7 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DEAD PF00270.29 EPE33271.1 - 7.9e-34 116.9 0.1 6.6e-16 58.6 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE33271.1 - 1.3e-22 80.3 0.0 1.6e-21 76.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE33271.1 - 3.1e-07 30.5 0.0 3.1e-07 30.5 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EPE33271.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PIGA PF08288.12 EPE33272.1 - 3.7e-46 155.7 3.3 5.1e-46 155.2 1.0 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EPE33272.1 - 9.6e-29 100.6 0.2 1.5e-28 99.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EPE33272.1 - 5.1e-25 88.0 0.0 7.5e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EPE33272.1 - 1.2e-24 87.3 0.2 2.1e-24 86.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EPE33272.1 - 9.8e-12 45.6 0.0 1.8e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EPE33272.1 - 6.2e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EPE33272.1 - 0.00034 21.0 0.0 0.0016 18.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Tyrosinase PF00264.20 EPE33273.1 - 4.7e-49 167.7 0.3 6.2e-49 167.3 0.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase 2-Hacid_dh_C PF02826.19 EPE33274.1 - 8.1e-42 142.6 0.0 2.8e-27 95.2 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EPE33274.1 - 0.015 15.4 0.0 0.023 14.9 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EPE33274.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 EPE33274.1 - 0.064 13.1 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPE33274.1 - 0.065 12.9 0.0 0.09 12.4 0.0 1.3 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 EPE33274.1 - 0.074 13.1 0.1 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 EPE33274.1 - 0.17 12.4 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain MFS_1 PF07690.16 EPE33275.1 - 1e-20 74.0 28.2 1e-20 74.0 28.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_6 PF12697.7 EPE33276.1 - 2.7e-11 44.5 0.6 3.9e-11 44.0 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE33276.1 - 2.9e-11 43.5 0.1 4.4e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE33276.1 - 7.3e-08 32.0 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EPE33276.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase TPP_enzyme_C PF02775.21 EPE33276.1 - 0.07 12.9 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF915 PF06028.11 EPE33276.1 - 0.093 12.1 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.14 EPE33276.1 - 0.16 10.7 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF3145 PF11343.8 EPE33276.1 - 0.24 10.9 1.3 3.2 7.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3145) Pkinase PF00069.25 EPE33277.1 - 1.2e-21 77.2 0.0 4.9e-21 75.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE33277.1 - 1.2e-12 47.7 0.0 7.6e-12 45.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase DUF5385 PF17359.2 EPE33277.1 - 0.052 13.1 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) APH PF01636.23 EPE33277.1 - 0.067 13.1 0.0 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3623 PF12291.8 EPE33278.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3623) CorA PF01544.18 EPE33279.1 - 0.072 12.4 11.3 0.27 10.5 9.4 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein SieB PF14163.6 EPE33279.1 - 0.57 9.7 1.7 1.5 8.3 1.7 1.7 1 0 0 1 1 1 0 Super-infection exclusion protein B Jiraiya PF15038.6 EPE33279.1 - 0.64 9.4 3.1 1.1 8.7 3.1 1.3 1 0 0 1 1 1 0 Jiraiya Pkinase PF00069.25 EPE33280.1 - 7.6e-18 64.8 0.0 1.6e-17 63.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE33280.1 - 7.5e-08 32.0 0.0 3.5e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_28 PF00295.17 EPE33281.1 - 7.9e-31 107.3 6.2 1.1e-30 106.9 6.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 EPE33281.1 - 0.024 14.5 13.8 0.087 12.7 0.0 3.3 1 1 1 3 3 3 0 Pectate lyase superfamily protein Fungal_trans_2 PF11951.8 EPE33282.1 - 1.3e-63 215.1 0.0 1.6e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE33282.1 - 2.6e-05 24.2 7.2 2.6e-05 24.2 7.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.25 EPE33284.1 - 6.2e-07 29.7 0.0 1.6e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE33284.1 - 1.4e-05 25.0 0.0 0.018 15.0 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 EPE33284.1 - 0.00027 21.6 0.0 0.0039 17.9 0.0 2.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE33284.1 - 0.0011 19.3 0.0 0.0029 18.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPE33284.1 - 0.0023 18.0 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase HSP70 PF00012.20 EPE33285.1 - 1e-61 208.9 7.8 6.3e-56 189.8 1.3 2.7 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EPE33285.1 - 0.0011 17.8 0.1 0.006 15.5 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Pkinase PF00069.25 EPE33286.1 - 4.1e-17 62.4 0.0 6.8e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE33286.1 - 1.3e-16 60.6 0.0 2.2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 EPE33286.1 - 2.9e-14 53.4 0.0 1.4e-05 25.5 0.0 4.1 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE33286.1 - 2.2e-09 36.8 0.1 0.00089 19.5 0.0 5.5 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 EPE33286.1 - 2.8e-07 30.9 0.0 0.00089 19.8 0.0 4.5 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE33286.1 - 7.2e-06 26.2 0.1 0.0085 16.4 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Pkinase_fungal PF17667.1 EPE33286.1 - 0.00019 20.4 0.1 0.00029 19.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EPE33286.1 - 0.0051 16.2 0.2 0.012 15.0 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ank PF00023.30 EPE33286.1 - 0.011 16.2 0.1 0.31 11.6 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat HeLo PF14479.6 EPE33287.1 - 8e-21 74.8 0.0 1.2e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation Androgen_recep PF02166.16 EPE33287.1 - 0.045 12.6 0.2 0.059 12.2 0.2 1.1 1 0 0 1 1 1 0 Androgen receptor GCIP PF13324.6 EPE33287.1 - 0.09 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF4449 PF14613.6 EPE33289.1 - 1.1e-66 224.0 3.2 1.1e-66 224.0 3.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Ank_2 PF12796.7 EPE33291.1 - 6.9e-49 164.4 16.7 2.4e-10 40.9 0.4 11.5 3 2 8 12 12 12 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE33291.1 - 9.9e-36 121.7 10.0 0.00052 20.5 0.0 12.8 8 2 4 13 13 13 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE33291.1 - 3.2e-33 110.0 21.9 0.47 11.2 0.0 17.7 18 0 0 18 18 18 10 Ankyrin repeat Ank PF00023.30 EPE33291.1 - 1.3e-28 98.1 35.8 0.0026 18.1 0.1 15.0 15 0 0 15 15 15 9 Ankyrin repeat Clr5 PF14420.6 EPE33291.1 - 1e-18 67.3 0.8 2.3e-18 66.2 0.8 1.6 1 0 0 1 1 1 1 Clr5 domain Ank_5 PF13857.6 EPE33291.1 - 1.2e-17 63.8 16.3 0.029 14.7 0.0 12.2 11 2 2 13 13 13 4 Ankyrin repeats (many copies) Phage_holin_2_4 PF16082.5 EPE33292.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Abhydrolase_4 PF08386.10 EPE33293.1 - 5.1e-20 71.5 0.1 1.4e-19 70.1 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 EPE33293.1 - 6.1e-19 68.7 0.1 5.6e-08 32.7 0.0 3.2 3 0 0 3 3 3 3 alpha/beta hydrolase fold DUF2206 PF09971.9 EPE33294.1 - 0.0093 14.8 0.1 0.18 10.5 0.0 2.4 2 0 0 2 2 2 2 Predicted membrane protein (DUF2206) GTP_EFTU PF00009.27 EPE33295.1 - 2.4e-56 190.4 0.1 3.1e-56 190.0 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EPE33295.1 - 1.3e-28 99.5 0.0 2.8e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EPE33295.1 - 2e-17 63.4 4.4 4.8e-17 62.1 4.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EPE33295.1 - 5.6e-06 26.4 0.0 3.1e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPE33295.1 - 0.00085 19.3 0.0 0.0029 17.5 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 EPE33295.1 - 0.04 13.5 0.1 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EPE33295.1 - 0.046 13.5 0.3 6.9 6.4 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HET PF06985.11 EPE33296.1 - 1.3e-31 109.9 0.0 3.2e-31 108.6 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) YafO_toxin PF13957.6 EPE33296.1 - 0.074 13.1 0.6 0.23 11.5 0.1 2.0 2 0 0 2 2 2 0 Toxin YafO, type II toxin-antitoxin system Asp PF00026.23 EPE33297.1 - 6.3e-77 259.1 0.4 6.4e-66 222.9 1.3 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPE33297.1 - 2.6e-09 37.6 0.6 0.00032 21.0 0.0 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Ribosomal_S7 PF00177.21 EPE33298.1 - 2.4e-36 124.6 2.5 3e-36 124.3 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e STT3 PF02516.14 EPE33299.1 - 1.2 8.0 7.0 0.19 10.6 3.4 1.4 2 0 0 2 2 2 0 Oligosaccharyl transferase STT3 subunit Mito_carr PF00153.27 EPE33300.1 - 2.3e-66 219.8 5.1 4.1e-24 84.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 EPE33300.1 - 0.042 13.6 0.6 0.14 11.9 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) HET PF06985.11 EPE33301.1 - 1.3e-19 71.0 0.1 1.1e-11 45.3 0.1 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_57 PF03065.15 EPE33301.1 - 0.044 13.0 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Alpha-2-MRAP_N PF06400.11 EPE33302.1 - 0.015 15.3 5.2 0.07 13.1 1.2 2.8 2 1 1 3 3 3 0 Alpha-2-macroglobulin RAP, N-terminal domain HTH_19 PF12844.7 EPE33302.1 - 0.06 13.4 0.4 0.19 11.8 0.4 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain TruB_C PF09142.11 EPE33302.1 - 0.24 11.2 1.4 0.9 9.4 0.1 2.5 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Laminin_II PF06009.12 EPE33302.1 - 0.3 11.1 4.9 1.3 9.1 4.9 2.1 1 0 0 1 1 1 0 Laminin Domain II CENP-X PF09415.10 EPE33303.1 - 1.5e-20 73.3 0.0 3.4e-20 72.1 0.0 1.6 2 0 0 2 2 2 1 CENP-S associating Centromere protein X PAP1 PF08601.10 EPE33303.1 - 1.7 8.3 13.2 2.1 8.0 13.2 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 KAR9 PF08580.10 EPE33303.1 - 5 5.5 13.5 5.8 5.3 13.5 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Cu_bind_like PF02298.17 EPE33305.1 - 0.017 15.1 0.2 0.05 13.6 0.2 1.7 1 1 0 1 1 1 0 Plastocyanin-like domain Mito_fiss_Elm1 PF06258.11 EPE33305.1 - 0.038 13.1 0.3 0.067 12.3 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial fission ELM1 Copper-bind PF00127.20 EPE33305.1 - 0.073 13.5 0.6 0.16 12.4 0.6 1.6 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family DUF1180 PF06679.12 EPE33305.1 - 4.1 7.8 12.1 0.69 10.3 7.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Cyt-b5 PF00173.28 EPE33306.1 - 2.3e-12 46.9 0.1 3.5e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_S25 PF03297.15 EPE33307.1 - 3.7e-37 126.6 5.4 4e-37 126.5 5.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 EPE33307.1 - 0.011 15.3 0.1 0.022 14.3 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.12 EPE33307.1 - 0.012 15.3 0.1 0.016 14.9 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain MarR_2 PF12802.7 EPE33307.1 - 0.014 15.3 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 EPE33307.1 - 0.046 14.1 0.1 0.068 13.5 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator PspB PF06667.12 EPE33308.1 - 0.064 13.3 0.1 0.74 9.9 0.0 2.3 2 0 0 2 2 2 0 Phage shock protein B Pmp3 PF01679.17 EPE33308.1 - 1.5 9.1 4.7 4.6 7.5 1.2 2.8 3 0 0 3 3 3 0 Proteolipid membrane potential modulator MFS_1 PF07690.16 EPE33309.1 - 9.1e-35 120.2 21.7 9.5e-35 120.1 20.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily GP41 PF00517.17 EPE33309.1 - 0.12 12.3 0.3 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 Retroviral envelope protein Adeno_E3_CR2 PF02439.15 EPE33309.1 - 0.16 11.7 0.9 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Glyco_hydro_76 PF03663.14 EPE33310.1 - 3.8e-145 484.0 8.8 4.8e-145 483.7 8.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EPE33310.1 - 6e-05 22.3 1.4 0.1 11.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 BTB_2 PF02214.22 EPE33311.1 - 9.3e-05 22.7 0.6 0.00026 21.3 0.6 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EPE33311.1 - 0.00021 21.5 0.0 0.00037 20.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain adh_short PF00106.25 EPE33312.1 - 4.3e-41 140.5 0.0 6e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE33312.1 - 5.9e-27 94.7 0.0 8.3e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE33312.1 - 7.9e-07 29.2 0.0 1.2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EPE33312.1 - 0.00017 21.1 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 EPE33312.1 - 0.043 13.8 0.2 0.089 12.8 0.1 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase SSB PF00436.25 EPE33312.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Single-strand binding protein family YajC PF02699.15 EPE33312.1 - 0.15 11.9 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit DASH_Duo1 PF08651.10 EPE33312.1 - 0.21 11.4 0.1 0.66 9.8 0.0 1.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 TRI12 PF06609.13 EPE33314.1 - 5.8e-39 134.0 23.3 6.9e-39 133.7 23.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EPE33314.1 - 3.5e-12 45.9 50.8 4.5e-12 45.6 46.1 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Saf_2TM PF18303.1 EPE33314.1 - 0.055 13.1 0.7 0.86 9.2 0.2 2.6 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF3087 PF11286.8 EPE33314.1 - 0.32 10.5 3.3 3.8 7.0 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) p450 PF00067.22 EPE33315.1 - 7.8e-69 232.6 0.0 1.1e-68 232.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AtuA PF07287.11 EPE33316.1 - 6e-128 426.5 0.7 7.2e-128 426.2 0.7 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA DUF1134 PF06577.12 EPE33316.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) Cyclase PF04199.13 EPE33317.1 - 6.4e-11 42.6 0.0 1.2e-10 41.8 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase 2-Hacid_dh_C PF02826.19 EPE33318.1 - 3.2e-39 134.1 0.0 4.7e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPE33318.1 - 1.9e-11 43.8 0.0 2.5e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EPE33318.1 - 0.0065 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EPE33318.1 - 0.052 14.1 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PLU-1 PF08429.11 EPE33319.1 - 2.6e-115 385.2 18.3 8.4e-113 377.0 17.0 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 EPE33319.1 - 1.7e-43 147.7 0.1 4.7e-43 146.2 0.1 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 EPE33319.1 - 8.8e-23 80.8 0.1 3e-22 79.1 0.1 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 EPE33319.1 - 2.2e-17 62.7 31.1 3.3e-09 36.5 7.6 3.6 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.17 EPE33319.1 - 1.4e-15 56.9 1.4 3.8e-15 55.5 1.4 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 EPE33319.1 - 9.3e-12 45.2 5.5 2.6e-11 43.7 5.5 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.6 EPE33319.1 - 0.029 14.0 8.8 0.1 12.2 1.5 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 EPE33319.1 - 0.73 9.8 20.1 0.5 10.3 3.3 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2203 PF09969.9 EPE33319.1 - 0.93 10.2 5.5 3.5 8.3 0.5 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) zf-RING_2 PF13639.6 EPE33319.1 - 7.1 7.1 23.1 7.8 6.9 8.2 2.7 2 0 0 2 2 2 0 Ring finger domain GIY-YIG PF01541.24 EPE33320.1 - 1.1e-14 54.4 0.0 2.8e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H_2 PF13832.6 EPE33320.1 - 0.00032 20.8 1.9 0.00066 19.8 1.9 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EPE33320.1 - 0.00048 20.3 2.3 0.0011 19.2 2.3 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain FANCL_C PF11793.8 EPE33320.1 - 0.0011 19.2 3.6 0.0023 18.0 3.6 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.29 EPE33320.1 - 0.049 13.5 7.6 0.043 13.7 5.8 1.9 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 EPE33320.1 - 0.055 13.4 4.0 0.21 11.6 1.8 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 EPE33320.1 - 0.13 11.9 3.4 0.31 10.7 3.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 EPE33320.1 - 0.29 11.5 5.8 0.54 10.6 5.8 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING-like PF08746.11 EPE33320.1 - 1.7 9.1 8.1 0.3 11.4 3.8 2.1 2 1 0 2 2 2 0 RING-like domain COesterase PF00135.28 EPE33321.1 - 3.3e-90 303.4 0.0 8.2e-90 302.1 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE33321.1 - 8.7e-06 25.7 0.3 0.00099 19.0 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPE33321.1 - 0.025 14.0 0.4 0.046 13.2 0.4 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 EPE33321.1 - 0.1 11.5 0.0 3.2 6.5 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase TPR_2 PF07719.17 EPE33322.1 - 0.00026 20.9 0.0 2.1 8.7 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat UBA PF00627.31 EPE33322.1 - 0.00053 19.8 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain TPR_1 PF00515.28 EPE33322.1 - 0.0031 17.3 0.0 2 8.4 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat DnaJ PF00226.31 EPE33322.1 - 0.18 12.0 1.1 0.52 10.5 0.0 2.1 2 0 0 2 2 2 0 DnaJ domain DUF1688 PF07958.11 EPE33323.1 - 6.4e-182 604.9 0.0 7.2e-182 604.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) SNF2_N PF00176.23 EPE33324.1 - 3.5e-06 26.0 0.0 1.1e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain DUF676 PF05057.14 EPE33326.1 - 2.4e-07 30.5 0.0 1.9e-06 27.5 0.0 2.2 2 1 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EPE33326.1 - 0.0019 18.8 0.0 0.0031 18.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EPE33326.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 EPE33326.1 - 0.2 10.9 0.0 0.46 9.7 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Methyltransf_11 PF08241.12 EPE33327.1 - 3.7e-08 33.9 0.0 6.4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE33327.1 - 1.1e-05 26.1 0.0 1.6e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE33327.1 - 2.1e-05 24.3 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE33327.1 - 0.00012 22.7 0.0 0.00019 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EPE33327.1 - 0.00028 20.8 0.0 0.0004 20.3 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.18 EPE33327.1 - 0.0017 17.8 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EPE33327.1 - 0.023 14.3 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.19 EPE33327.1 - 0.091 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase AA_permease_2 PF13520.6 EPE33329.1 - 1.3e-52 179.1 38.2 2.9e-52 177.9 38.2 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE33329.1 - 1.1e-05 24.3 37.4 7.3e-05 21.5 21.4 2.8 2 1 0 2 2 2 2 Amino acid permease DUF2207 PF09972.9 EPE33329.1 - 0.12 11.1 0.0 0.12 11.1 0.0 3.7 1 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF2070 PF09843.9 EPE33329.1 - 0.35 9.1 19.2 0.61 8.3 8.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Glyco_hyd_65N_2 PF14498.6 EPE33330.1 - 7.3e-60 202.8 0.9 1.1e-59 202.2 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Pyr_redox_2 PF07992.14 EPE33331.1 - 2.6e-32 112.3 0.0 3.5e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE33331.1 - 6.1e-14 52.3 0.0 5e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE33331.1 - 0.00035 20.7 0.0 0.047 13.9 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPE33331.1 - 0.00049 19.3 0.0 0.16 11.0 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein K_oxygenase PF13434.6 EPE33331.1 - 0.0015 17.7 0.0 0.24 10.5 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EPE33331.1 - 0.0016 18.1 0.1 1.6 8.3 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPE33331.1 - 0.0029 16.9 0.0 0.91 8.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase RuvA_N PF01330.21 EPE33331.1 - 0.0041 17.2 0.0 0.34 11.0 0.0 2.8 2 0 0 2 2 2 1 RuvA N terminal domain TrkA_N PF02254.18 EPE33331.1 - 0.0057 16.9 0.0 4.4 7.6 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain Eno-Rase_NADH_b PF12242.8 EPE33331.1 - 0.006 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HI0933_like PF03486.14 EPE33331.1 - 0.035 12.8 0.0 5.4 5.6 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 EPE33331.1 - 0.045 13.0 0.1 0.33 10.1 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 EPE33331.1 - 0.066 13.2 0.2 2 8.4 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding ApbA PF02558.16 EPE33331.1 - 0.078 12.6 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 EPE33331.1 - 0.11 11.4 0.0 4.5 6.0 0.0 2.7 2 1 1 3 3 3 0 Tryptophan halogenase Thi4 PF01946.17 EPE33331.1 - 0.11 11.7 0.0 7.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Thi4 family DUF1188 PF06690.11 EPE33331.1 - 0.17 11.4 0.1 0.85 9.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) NmrA PF05368.13 EPE33332.1 - 3.4e-24 85.7 0.0 4.3e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE33332.1 - 9.9e-09 35.3 0.0 2.2e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EPE33332.1 - 0.17 12.2 0.0 0.54 10.5 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Glyco_transf_21 PF13506.6 EPE33334.1 - 9.9e-11 41.4 0.0 0.00023 20.7 0.0 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EPE33334.1 - 0.00069 19.6 0.0 0.0022 17.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EPE33334.1 - 0.0013 18.6 0.0 0.006 16.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 tRNA_int_endo PF01974.17 EPE33335.1 - 2.8e-20 72.1 0.2 5.7e-20 71.2 0.2 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EPE33335.1 - 0.0013 18.4 0.0 0.35 10.6 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain DUF1907 PF08925.11 EPE33335.1 - 0.23 10.9 0.0 0.36 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1907) HET PF06985.11 EPE33336.1 - 5.6e-12 46.2 10.8 5.3e-10 39.8 2.5 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Na_Ca_ex PF01699.24 EPE33338.1 - 2.3e-26 92.6 22.6 3.4e-15 56.3 10.1 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1298 PF06974.13 EPE33338.1 - 0.0061 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Rubella_E2 PF05749.11 EPE33338.1 - 0.054 12.9 0.4 0.24 10.8 0.7 1.8 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 Ank_2 PF12796.7 EPE33339.1 - 4.5e-175 568.8 11.8 6.2e-15 55.6 0.1 18.8 3 3 15 20 20 20 20 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE33339.1 - 1.4e-116 379.4 18.7 2.3e-09 37.6 0.1 24.2 10 6 19 29 29 29 27 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE33339.1 - 3.3e-110 346.5 11.4 1.5e-05 25.0 0.0 36.0 37 0 0 37 37 37 23 Ankyrin repeat Ank_5 PF13857.6 EPE33339.1 - 2e-99 324.4 28.6 6.9e-07 29.4 0.0 26.6 10 8 18 29 29 29 25 Ankyrin repeats (many copies) Ank PF00023.30 EPE33339.1 - 1.8e-97 315.9 21.0 8.2e-08 32.4 0.0 34.1 33 2 0 33 33 33 21 Ankyrin repeat ZZ PF00569.17 EPE33339.1 - 3.1e-05 23.7 6.3 7.2e-05 22.5 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Sulfate_transp PF00916.20 EPE33339.1 - 0.11 11.3 0.4 0.81 8.4 0.0 2.1 2 0 0 2 2 2 0 Sulfate permease family 4HB_MCP_1 PF12729.7 EPE33339.1 - 0.57 9.7 6.5 1.7 8.1 6.5 1.8 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Adaptin_binding PF10199.9 EPE33339.1 - 0.59 10.7 6.9 40 4.9 3.8 3.3 3 1 0 3 3 3 0 Alpha and gamma adaptin binding protein p34 AAA PF00004.29 EPE33340.1 - 3.5e-16 59.8 0.0 7.2e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE33340.1 - 0.0012 19.2 0.1 0.0033 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain CPT PF07931.12 EPE33340.1 - 0.0017 18.2 0.0 0.054 13.3 0.0 2.5 1 1 1 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.6 EPE33340.1 - 0.0054 17.0 0.7 0.17 12.2 0.2 2.4 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 EPE33340.1 - 0.029 14.1 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EPE33340.1 - 0.039 13.7 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EPE33340.1 - 0.058 13.4 0.0 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EPE33340.1 - 0.21 11.3 0.0 0.42 10.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 EPE33341.1 - 0.063 13.7 0.1 0.35 11.2 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain Ank_2 PF12796.7 EPE33342.1 - 4.8e-47 158.5 2.2 8.4e-15 55.1 0.0 6.2 2 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE33342.1 - 1.2e-39 134.2 3.5 3.5e-07 30.7 0.0 7.9 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE33342.1 - 6.1e-34 112.2 6.8 0.0091 16.4 0.1 10.7 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 EPE33342.1 - 5.6e-28 96.7 12.1 0.00016 21.9 0.1 8.1 4 1 4 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.30 EPE33342.1 - 3.3e-24 84.2 8.5 0.00076 19.8 0.0 10.6 9 1 1 10 10 10 6 Ankyrin repeat NACHT PF05729.12 EPE33342.1 - 1.1e-07 32.0 0.0 2.9e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EPE33342.1 - 1.7e-05 25.2 0.0 0.0001 22.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EPE33342.1 - 0.02 15.2 0.0 0.061 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EPE33342.1 - 0.084 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 EPE33342.1 - 0.11 12.7 0.0 0.42 10.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 EPE33343.1 - 7.4e-73 245.9 0.0 9.8e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.21 EPE33346.1 - 3.9e-11 42.7 1.6 6.5e-11 42.0 1.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HET PF06985.11 EPE33347.1 - 1.6e-32 112.9 0.7 2.6e-32 112.2 0.7 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nbas_N PF15492.6 EPE33347.1 - 0.034 13.5 0.3 0.63 9.3 0.0 2.5 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal AMP-binding PF00501.28 EPE33348.1 - 2.9e-25 88.8 0.0 1.4e-24 86.5 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EPE33348.1 - 4.5e-21 75.2 0.0 5.9e-18 65.0 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein Epimerase PF01370.21 EPE33348.1 - 6.2e-09 35.7 0.0 1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EPE33348.1 - 0.045 14.2 0.0 0.089 13.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ank_2 PF12796.7 EPE33349.1 - 5.1e-42 142.3 3.9 4.2e-16 59.3 0.2 5.0 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE33349.1 - 3.3e-30 104.1 2.1 1e-10 41.9 0.0 5.7 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE33349.1 - 7.9e-28 93.4 7.8 0.013 16.0 0.0 8.5 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 EPE33349.1 - 3.9e-23 80.8 16.4 9.5e-05 22.7 0.0 9.3 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 EPE33349.1 - 1.2e-21 76.4 0.8 7.9e-07 29.2 0.0 6.2 4 2 2 7 7 7 3 Ankyrin repeats (many copies) zf-C2H2 PF00096.26 EPE33350.1 - 0.001 19.4 6.8 0.22 12.1 1.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 EPE33350.1 - 0.0077 16.8 0.2 0.021 15.4 0.2 1.8 1 0 0 1 1 1 1 FOXP coiled-coil domain CxC6 PF18721.1 EPE33350.1 - 0.032 14.5 1.2 0.075 13.3 1.2 1.6 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases zf-C2H2_4 PF13894.6 EPE33350.1 - 1 10.4 3.5 11 7.1 0.6 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger Ank_2 PF12796.7 EPE33351.1 - 8.1e-41 138.5 1.5 3.4e-12 46.8 0.4 4.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE33351.1 - 1.1e-36 124.7 0.4 1.4e-08 35.1 0.0 6.1 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EPE33351.1 - 3.4e-23 81.0 17.8 0.00034 20.9 0.0 9.1 9 1 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.6 EPE33351.1 - 5.9e-23 78.5 9.5 0.0032 17.8 0.0 9.0 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EPE33351.1 - 5.1e-22 77.7 6.5 1.4e-07 31.6 0.3 6.1 1 1 4 6 6 6 6 Ankyrin repeats (many copies) DUF3447 PF11929.8 EPE33351.1 - 0.031 14.2 0.0 0.27 11.2 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3447) zf-C2H2 PF00096.26 EPE33352.1 - 7e-07 29.4 10.0 0.00077 19.8 2.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type ZnuA PF01297.17 EPE33352.1 - 0.044 13.2 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic zf-C2H2_4 PF13894.6 EPE33352.1 - 0.077 13.9 9.4 0.22 12.4 1.3 3.2 3 1 0 3 3 3 0 C2H2-type zinc finger Beta_helix PF13229.6 EPE33353.1 - 3e-13 49.9 26.9 2.7e-09 37.1 8.9 2.6 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EPE33353.1 - 1.9e-11 43.7 8.5 8.3e-09 35.1 0.6 2.6 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Pkinase PF00069.25 EPE33355.1 - 9.7e-18 64.5 0.0 1.4e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE33355.1 - 3.3e-13 49.5 0.0 4.6e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EPE33355.1 - 7.5e-06 25.4 0.1 1.1e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EPE33355.1 - 0.0013 17.6 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EPE33355.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EPE33355.1 - 0.084 12.8 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_4 PF13637.6 EPE33356.1 - 4.3e-17 62.2 0.5 1.2e-08 35.3 0.3 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE33356.1 - 5.4e-14 52.5 0.2 1e-12 48.4 0.2 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE33356.1 - 2.5e-13 49.9 2.2 1.6e-10 41.0 0.2 2.7 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE33356.1 - 5e-11 41.8 0.7 1.3e-06 28.3 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeat Ank PF00023.30 EPE33356.1 - 7.3e-10 38.9 4.6 5.4e-08 32.9 0.1 3.3 3 1 0 3 3 3 2 Ankyrin repeat DUF917 PF06032.12 EPE33357.1 - 8.8e-105 350.4 0.4 1.4e-103 346.4 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 EPE33357.1 - 3e-22 79.2 5.9 3.7e-19 69.1 1.5 2.6 1 1 1 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EPE33357.1 - 2.4e-19 69.7 0.1 9.3e-19 67.8 0.1 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Acetyltransf_1 PF00583.25 EPE33358.1 - 5.7e-08 33.0 0.0 8.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE33358.1 - 3.5e-07 30.2 0.0 5.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE33358.1 - 2.7e-06 27.7 0.0 4.7e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPE33358.1 - 3e-05 24.1 0.1 5.4e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPE33358.1 - 0.00022 21.3 0.0 0.00047 20.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EPE33358.1 - 0.14 12.1 0.1 0.65 10.0 0.0 2.0 1 1 1 2 2 2 0 FR47-like protein 2-Hacid_dh_C PF02826.19 EPE33360.1 - 1.7e-44 151.3 0.0 1.1e-43 148.7 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPE33360.1 - 3.6e-05 23.4 0.0 4.9e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ADH_N PF08240.12 EPE33361.1 - 6.7e-27 93.5 2.1 1.5e-26 92.4 2.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE33361.1 - 2.1e-16 60.1 0.0 3.2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EPE33361.1 - 7.7e-05 22.3 1.4 0.0067 15.9 0.3 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ATP-synt_G PF04718.15 EPE33362.1 - 1.7e-35 121.8 1.7 1.1e-34 119.2 0.1 2.1 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF883 PF05957.13 EPE33362.1 - 0.007 17.0 2.5 0.014 16.0 2.5 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Phasin_2 PF09361.10 EPE33362.1 - 0.011 16.0 4.0 0.079 13.2 3.0 2.2 2 0 0 2 2 2 0 Phasin protein PhaP_Bmeg PF09602.10 EPE33362.1 - 0.1 12.5 0.1 0.96 9.4 0.0 1.9 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Senescence PF06911.12 EPE33362.1 - 0.65 10.3 11.8 1.6 9.0 11.8 1.8 1 1 0 1 1 1 0 Senescence-associated protein Ig_mannosidase PF17753.1 EPE33363.1 - 1e-20 73.2 0.0 2.6e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain Mannosidase_ig PF17786.1 EPE33363.1 - 4e-11 43.4 0.1 1.3e-10 41.7 0.1 1.9 1 1 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EPE33363.1 - 1.6e-05 25.6 0.0 4.4e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 MCM_bind PF09739.9 EPE33364.1 - 0.15 10.5 3.8 0.21 10.0 3.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor AA_permease_2 PF13520.6 EPE33365.1 - 4.1e-53 180.8 58.7 5.2e-53 180.4 58.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE33365.1 - 3.8e-25 88.4 49.6 5.2e-25 88.0 49.6 1.1 1 0 0 1 1 1 1 Amino acid permease zf-C2H2 PF00096.26 EPE33366.1 - 0.03 14.8 1.6 0.095 13.2 1.6 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type TRI12 PF06609.13 EPE33366.1 - 0.16 10.4 0.5 0.24 9.7 0.5 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Patatin PF01734.22 EPE33367.1 - 5e-14 53.0 0.0 1.2e-13 51.7 0.0 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase HTH_29 PF13551.6 EPE33367.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn helix MgpC PF05220.12 EPE33368.1 - 0.075 12.3 0.1 0.22 10.8 0.0 1.7 1 1 0 2 2 2 0 MgpC protein precursor DUF3253 PF11625.8 EPE33370.1 - 6.6e-23 80.7 0.0 7.8e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) Sfi1 PF08457.10 EPE33370.1 - 0.15 10.6 0.0 0.16 10.4 0.0 1.0 1 0 0 1 1 1 0 Sfi1 spindle body protein MARVEL PF01284.23 EPE33371.1 - 0.00026 21.0 8.6 0.00063 19.8 8.7 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF3445 PF11927.8 EPE33372.1 - 9.3e-77 257.7 0.0 3.4e-75 252.5 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3445) DnaJ_C PF01556.18 EPE33373.1 - 4.4e-28 98.2 0.0 6.5e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EPE33373.1 - 6.9e-26 90.2 1.8 1.1e-25 89.5 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EPE33373.1 - 1.3e-13 51.1 16.0 2.2e-13 50.4 16.0 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EPE33373.1 - 2.7e-05 24.0 6.2 0.057 13.4 2.1 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EPE33373.1 - 0.0013 18.7 6.8 0.22 11.6 0.5 2.2 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 EPE33373.1 - 3.6 7.2 6.6 6.9 6.3 0.4 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Lar_restr_allev PF14354.6 EPE33373.1 - 8.9 6.8 9.2 2.6 8.5 1.3 3.0 1 1 2 3 3 3 0 Restriction alleviation protein Lar OB_NTP_bind PF07717.16 EPE33374.1 - 5.2e-22 78.0 0.0 1.5e-21 76.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EPE33374.1 - 5.9e-20 71.6 0.2 5.9e-20 71.6 0.2 4.0 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EPE33374.1 - 8.1e-15 55.1 0.1 5.4e-14 52.5 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPE33374.1 - 1.9e-05 24.5 0.1 8.3e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EPE33374.1 - 0.00015 22.1 0.4 0.00049 20.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EPE33374.1 - 0.00015 21.5 0.1 0.00042 20.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EPE33374.1 - 0.004 16.3 0.0 0.01 14.9 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EPE33374.1 - 0.013 15.8 0.1 0.036 14.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EPE33374.1 - 0.041 13.5 0.1 0.092 12.4 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain cobW PF02492.19 EPE33374.1 - 0.17 11.4 0.6 2.1 7.9 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 EPE33374.1 - 0.21 12.1 0.0 0.21 12.1 0.0 2.6 2 1 0 2 2 2 0 ABC transporter RhgB_N PF09284.10 EPE33375.1 - 2.1e-104 348.5 2.2 3e-104 348.0 2.2 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 EPE33375.1 - 6.5e-42 143.2 0.1 3.6e-41 140.8 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EPE33375.1 - 7.3e-21 73.7 5.0 7.3e-21 73.7 5.0 3.4 4 1 0 4 4 4 1 Polysaccharide lyase family 4, domain II TPK_B1_binding PF04265.14 EPE33375.1 - 0.11 12.2 0.0 2 8.2 0.0 2.5 2 0 0 2 2 2 0 Thiamin pyrophosphokinase, vitamin B1 binding domain CarboxypepD_reg PF13620.6 EPE33375.1 - 0.2 12.0 4.5 0.26 11.6 1.1 3.1 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain CARDB PF07705.11 EPE33375.1 - 1.9 8.8 4.0 1.4 9.2 0.4 2.4 2 0 0 2 2 2 0 CARDB Methyltransf_23 PF13489.6 EPE33376.1 - 3.7e-14 52.9 0.0 4.9e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE33376.1 - 3.4e-08 34.0 0.0 4.6e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE33376.1 - 5.6e-07 30.2 0.0 7.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE33376.1 - 8.6e-05 23.2 0.0 0.00013 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE33376.1 - 0.0002 21.2 0.0 0.0003 20.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EPE33376.1 - 0.0034 16.3 0.0 0.0042 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EPE33376.1 - 0.0038 16.5 0.0 0.0051 16.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 EPE33376.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TFIIIC_sub6 PF10419.9 EPE33377.1 - 4.9e-22 77.6 0.0 1.3e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain zf-CCHC PF00098.23 EPE33380.1 - 0.00065 19.7 2.6 0.00065 19.7 2.6 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 EPE33380.1 - 0.015 15.1 1.4 0.038 13.8 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3245 PF11595.8 EPE33381.1 - 0.25 11.8 0.7 0.38 11.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Sugar_tr PF00083.24 EPE33382.1 - 1.2e-127 426.5 21.2 1.4e-127 426.3 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE33382.1 - 2.5e-16 59.6 34.4 1.7e-11 43.6 16.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily APG5 PF04106.12 EPE33383.1 - 1.9e-32 112.7 0.0 2.1e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg5 2OG-FeII_Oxy_3 PF13640.6 EPE33384.1 - 1.1e-08 35.8 0.0 2.5e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4360 PF14273.6 EPE33386.1 - 1.9e-65 220.1 4.0 2.3e-65 219.8 4.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) HET PF06985.11 EPE33387.1 - 0.0018 18.7 0.0 0.003 17.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Na_Ca_ex PF01699.24 EPE33388.1 - 8.6e-36 123.2 38.2 3.1e-21 75.9 19.3 3.0 2 1 0 2 2 2 2 Sodium/calcium exchanger protein EssA PF10661.9 EPE33388.1 - 0.013 15.3 0.6 0.11 12.3 0.3 2.6 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA VCX_VCY PF15231.6 EPE33388.1 - 4.1 8.1 18.2 0.15 12.8 6.4 2.6 2 0 0 2 2 2 0 Variable charge X/Y family CVNH PF08881.10 EPE33390.1 - 0.078 13.7 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 CVNH domain CDC50 PF03381.15 EPE33391.1 - 5e-96 321.5 0.0 6.1e-96 321.2 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SAE2 PF08573.10 EPE33392.1 - 1.1e-34 119.8 0.2 1.1e-34 119.8 0.2 2.9 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus TPR_12 PF13424.6 EPE33392.1 - 5.7e-22 77.8 16.8 0.00095 19.4 0.8 6.7 5 1 1 6 6 6 6 Tetratricopeptide repeat SesA PF17107.5 EPE33392.1 - 3e-14 53.3 0.6 3e-14 53.3 0.6 2.9 2 1 1 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NB-ARC PF00931.22 EPE33392.1 - 7.1e-06 25.4 0.1 5.3e-05 22.5 0.0 2.4 2 1 0 2 2 2 1 NB-ARC domain TPR_MalT PF17874.1 EPE33392.1 - 0.0011 18.4 4.3 0.0011 18.4 4.3 2.7 3 0 0 3 3 3 1 MalT-like TPR region TPR_14 PF13428.6 EPE33392.1 - 0.0017 19.0 0.8 22 6.2 0.0 5.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EPE33392.1 - 0.002 18.7 1.1 46 4.8 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_16 PF13191.6 EPE33392.1 - 0.013 15.9 0.5 0.089 13.2 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain TPR_2 PF07719.17 EPE33392.1 - 0.025 14.7 13.1 13 6.2 0.0 7.7 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPE33392.1 - 0.078 12.9 14.7 1.9 8.4 0.0 7.0 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 EPE33392.1 - 0.37 10.7 4.7 17 5.4 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat GIT_CC PF16559.5 EPE33392.1 - 0.96 9.4 12.7 0.033 14.0 3.2 3.4 4 1 1 5 5 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor HALZ PF02183.18 EPE33392.1 - 1.1 9.5 11.2 2.3 8.5 1.0 3.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper TPR_8 PF13181.6 EPE33392.1 - 1.6 9.2 4.6 1.2e+02 3.2 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EPE33392.1 - 1.9 9.1 8.8 34 5.0 0.2 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 EPE33393.1 - 9.3e-41 140.6 0.0 2.8e-40 139.0 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPE33393.1 - 3.8e-15 55.9 0.0 8.6e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE33393.1 - 1.1e-06 28.1 0.1 4.6e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE33393.1 - 2.8e-06 27.2 0.0 3.5e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EPE33393.1 - 5.2e-06 26.9 0.4 1.1e-05 25.8 0.2 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPE33393.1 - 0.00024 21.1 0.1 0.0054 16.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EPE33393.1 - 0.00026 19.8 0.2 0.00046 19.0 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EPE33393.1 - 0.0038 16.5 0.1 0.0064 15.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EPE33393.1 - 0.0043 16.2 0.1 0.0062 15.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.19 EPE33393.1 - 0.016 13.7 0.2 0.034 12.6 0.1 1.5 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like FAD_oxidored PF12831.7 EPE33393.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EPE33393.1 - 0.027 13.7 0.1 0.047 12.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 EPE33393.1 - 0.065 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Prenylcys_lyase PF07156.14 EPE33393.1 - 0.067 12.3 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Prenylcysteine lyase 3HCDH_N PF02737.18 EPE33393.1 - 0.067 13.1 0.1 0.17 11.7 0.1 1.6 1 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EPE33393.1 - 0.16 11.6 0.2 0.4 10.3 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 EPE33393.1 - 0.23 10.7 0.5 0.43 9.8 0.2 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 EPE33394.1 - 1.9e-120 402.8 27.7 2.2e-120 402.6 27.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE33394.1 - 7.1e-20 71.2 30.3 7.1e-20 71.2 30.3 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DHquinase_I PF01487.15 EPE33396.1 - 3.7e-48 164.8 0.0 5.1e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SPT16 PF08644.11 EPE33397.1 - 8.4e-58 194.8 0.2 8.4e-58 194.8 0.2 2.6 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EPE33397.1 - 5.9e-54 182.2 0.1 2.3e-53 180.3 0.1 2.1 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EPE33397.1 - 2.9e-27 95.7 0.0 5.1e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EPE33397.1 - 1e-14 54.7 0.7 2.6e-14 53.4 0.1 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like RhodobacterPufX PF11511.8 EPE33398.1 - 0.00092 18.8 1.4 0.0026 17.3 0.5 2.0 2 0 0 2 2 2 1 Intrinsic membrane protein PufX HET PF06985.11 EPE33399.1 - 1.8e-26 93.2 0.1 4.1e-26 92.1 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GH131_N PF18271.1 EPE33404.1 - 2.7e-82 276.3 0.9 3e-82 276.2 0.9 1.0 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain SLAC1 PF03595.17 EPE33405.1 - 9.6e-77 258.4 50.2 1.1e-76 258.2 50.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Methyltransf_22 PF13383.6 EPE33407.1 - 3.1e-21 76.1 0.0 4.3e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 EPE33407.1 - 2.3e-10 40.8 0.0 3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Fungal_trans PF04082.18 EPE33408.1 - 6.1e-27 94.3 0.0 1.4e-26 93.1 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE33408.1 - 0.00072 19.6 13.2 0.0014 18.7 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF617 PF04759.13 EPE33408.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF617 Striatin PF08232.12 EPE33408.1 - 0.61 10.7 2.5 0.34 11.5 0.2 1.7 2 0 0 2 2 2 0 Striatin family Opy2 PF09463.10 EPE33408.1 - 5.9 7.3 7.6 13 6.3 7.6 1.5 1 0 0 1 1 1 0 Opy2 protein EthD PF07110.11 EPE33409.1 - 0.00097 20.2 0.0 0.32 12.2 0.0 2.2 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.6 EPE33409.1 - 0.0049 17.3 0.0 0.097 13.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4286) APH PF01636.23 EPE33411.1 - 3.6e-14 53.3 0.0 6.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE33411.1 - 0.0005 19.7 0.1 0.00098 18.8 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EPE33411.1 - 0.045 13.1 0.0 0.84 9.0 0.2 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rbsn PF11464.8 EPE33411.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Rabenosyn Rab binding domain RIO1 PF01163.22 EPE33411.1 - 0.086 12.4 0.1 3.6 7.1 0.1 2.5 2 0 0 2 2 2 0 RIO1 family adh_short PF00106.25 EPE33412.1 - 2.1e-12 46.9 0.0 1.7e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EPE33412.1 - 2.1e-05 24.5 0.1 4.2e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE33412.1 - 0.0018 17.5 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 EPE33412.1 - 0.006 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EPE33412.1 - 0.027 13.9 0.0 0.049 13.1 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPE33412.1 - 0.036 14.0 0.0 0.11 12.3 0.0 1.9 1 1 0 1 1 1 0 NAD(P)H-binding MFS_1 PF07690.16 EPE33414.1 - 1.8e-37 129.1 35.4 1.8e-37 129.1 35.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE33414.1 - 1.1e-07 31.2 10.7 2.7e-07 29.8 3.4 4.1 3 1 1 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.13 EPE33414.1 - 1.1e-05 24.0 0.7 1.1e-05 24.0 0.7 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2975 PF11188.8 EPE33416.1 - 0.76 9.7 6.2 7.4 6.5 1.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) HET PF06985.11 EPE33417.1 - 4.5e-26 92.0 0.0 1.6e-25 90.2 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.19 EPE33418.1 - 1.8e-17 63.6 0.0 7.1e-17 61.7 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EPE33418.1 - 1.4e-05 25.5 0.3 9.3e-05 22.9 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPE33418.1 - 7.5e-05 22.1 0.4 0.00018 20.8 0.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE33418.1 - 0.0034 17.0 0.3 0.4 10.2 0.3 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE33418.1 - 0.031 14.5 0.1 0.065 13.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DSBA PF01323.20 EPE33418.1 - 0.11 12.3 0.1 8.4 6.1 0.0 2.2 2 0 0 2 2 2 0 DSBA-like thioredoxin domain WD40 PF00400.32 EPE33420.1 - 1.9e-07 31.7 0.0 1.2 10.1 0.0 5.9 7 0 0 7 7 7 3 WD domain, G-beta repeat TPR_19 PF14559.6 EPE33422.1 - 1e-09 38.8 2.0 1.4e-08 35.1 0.4 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPE33422.1 - 3.3e-08 33.7 4.4 0.00012 22.6 0.1 4.2 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPE33422.1 - 7e-08 32.0 0.1 0.00025 20.9 0.2 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPE33422.1 - 2.1e-06 28.2 2.8 5.5e-05 23.7 0.2 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPE33422.1 - 7.9e-06 25.9 0.6 0.0063 16.8 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EPE33422.1 - 8.6e-06 25.3 0.2 0.041 13.6 0.1 3.6 3 1 1 4 4 4 2 TPR repeat TPR_8 PF13181.6 EPE33422.1 - 3.2e-05 23.8 0.4 0.0042 17.2 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 EPE33422.1 - 7.5e-05 23.0 1.1 0.0014 19.0 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EPE33422.1 - 0.00018 21.6 0.3 0.00053 20.1 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 EPE33422.1 - 0.0037 17.8 1.5 3.7 8.4 0.0 3.9 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EPE33422.1 - 0.011 15.6 0.1 0.57 10.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EPE33422.1 - 0.013 15.4 0.1 6 6.7 0.1 2.3 1 1 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_12 PF13424.6 EPE33422.1 - 0.033 14.5 1.5 0.46 10.8 0.6 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Borrelia_REV PF03978.13 EPE33422.1 - 0.047 13.6 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein Adaptin_N PF01602.20 EPE33423.1 - 4.9e-82 276.2 0.0 8.9e-82 275.3 0.0 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EPE33423.1 - 0.0016 18.5 0.0 0.02 14.9 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EPE33423.1 - 0.011 16.2 2.5 15 6.3 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat SMAP PF15477.6 EPE33424.1 - 3.6e-13 50.3 5.6 3.6e-13 50.3 5.6 5.0 4 1 0 4 4 4 1 Small acidic protein family LAGLIDADG_WhiA PF14527.6 EPE33424.1 - 0.019 15.0 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain RAMP4 PF06624.12 EPE33425.1 - 3.4e-22 78.3 0.1 3.7e-22 78.2 0.1 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF3152 PF11350.8 EPE33428.1 - 0.016 15.0 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Methyltransf_12 PF08242.12 EPE33429.1 - 1.3e-16 61.1 0.0 3.6e-16 59.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE33429.1 - 3.8e-15 56.3 0.0 7.7e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE33429.1 - 2.1e-11 43.9 0.0 3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE33429.1 - 1.1e-10 42.0 0.0 2.3e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE33429.1 - 1.9e-08 34.3 0.0 3.5e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE33429.1 - 1.3e-06 27.9 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 EPE33429.1 - 8.9e-05 21.8 0.0 0.26 10.4 0.0 2.4 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_24 PF13578.6 EPE33429.1 - 0.00014 22.8 0.0 0.00049 21.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Roc PF08477.13 EPE33429.1 - 0.00031 21.0 0.9 0.58 10.4 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MTS PF05175.14 EPE33429.1 - 0.00072 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EPE33429.1 - 0.07 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EPE33429.1 - 0.099 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 EPE33429.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_28 PF02636.17 EPE33429.1 - 0.12 12.0 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Polyketide_cyc PF03364.20 EPE33430.1 - 4.9e-21 75.3 0.0 1.1e-20 74.2 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EPE33430.1 - 0.063 13.6 0.0 1.3 9.3 0.0 2.2 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Kelch_1 PF01344.25 EPE33433.1 - 0.16 11.6 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Kelch motif DUF2583 PF10762.9 EPE33433.1 - 0.16 12.4 2.6 15 6.1 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) Ank_2 PF12796.7 EPE33434.1 - 9.1e-44 147.9 1.1 6e-09 36.4 0.0 8.0 8 0 0 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE33434.1 - 2.8e-29 101.1 5.2 5.4e-07 30.0 0.3 10.0 8 2 3 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE33434.1 - 9e-28 93.3 14.0 0.00058 20.1 0.0 11.4 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 EPE33434.1 - 1.5e-26 91.6 25.1 0.00053 20.3 0.0 12.0 13 0 0 13 13 12 7 Ankyrin repeat Pkinase PF00069.25 EPE33434.1 - 7.3e-25 87.8 0.0 1.3e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 EPE33434.1 - 2.5e-23 81.8 10.1 2.3e-07 30.9 0.0 7.9 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 EPE33434.1 - 1.8e-17 63.5 0.0 4.8e-17 62.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EPE33434.1 - 0.018 14.4 0.7 0.096 12.0 0.2 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sel1 PF08238.12 EPE33434.1 - 0.053 14.2 0.7 0.13 13.0 0.0 2.2 2 0 0 2 2 1 0 Sel1 repeat HEAT_2 PF13646.6 EPE33434.1 - 0.062 13.7 0.1 7.1 7.1 0.1 3.3 3 0 0 3 3 2 0 HEAT repeats Pkinase_fungal PF17667.1 EPE33434.1 - 0.077 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 EPE33435.1 - 5.9e-05 22.5 0.0 0.00068 19.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EPE33435.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Ldh_2 PF02615.14 EPE33436.1 - 7.2e-124 413.3 0.6 8.2e-124 413.1 0.6 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Acetyltransf_1 PF00583.25 EPE33437.1 - 2.4e-08 34.2 0.0 2.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE33437.1 - 0.0002 21.7 0.0 0.00026 21.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPE33437.1 - 0.00024 21.0 0.0 0.00036 20.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPE33437.1 - 0.00095 19.3 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase COG5 PF10392.9 EPE33439.1 - 0.00023 21.4 0.2 0.00023 21.4 0.2 2.5 3 0 0 3 3 3 1 Golgi transport complex subunit 5 2CSK_N PF08521.10 EPE33439.1 - 0.014 15.5 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal DEDD_Tnp_IS110 PF01548.17 EPE33439.1 - 0.11 12.3 0.4 0.59 10.0 0.7 1.9 2 0 0 2 2 2 0 Transposase EBP50_C PF09007.11 EPE33439.1 - 1.2 10.1 5.0 1.2 10.1 0.4 2.8 2 1 0 3 3 3 0 EBP50, C-terminal UQ_con PF00179.26 EPE33440.1 - 7.6e-09 35.3 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PARP PF00644.20 EPE33440.1 - 2.8e-07 30.3 0.1 7e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain RWD PF05773.22 EPE33440.1 - 0.1 12.9 0.0 0.32 11.3 0.0 1.9 1 0 0 1 1 1 0 RWD domain DNA_pol_phi PF04931.13 EPE33440.1 - 0.11 10.6 5.2 0.15 10.1 5.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 EPE33440.1 - 1.9 8.5 13.6 0.012 15.8 4.1 1.9 2 0 0 2 2 2 0 YL1 nuclear protein STAG PF08514.11 EPE33441.1 - 9.3e-32 109.3 0.1 9.3e-32 109.3 0.1 3.2 3 0 0 3 3 3 1 STAG domain HEAT_2 PF13646.6 EPE33441.1 - 0.0034 17.7 0.7 0.072 13.5 0.2 3.3 2 1 2 4 4 4 2 HEAT repeats Cnd1 PF12717.7 EPE33441.1 - 0.0044 17.1 1.5 0.29 11.2 0.0 4.1 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EPE33441.1 - 0.015 15.5 0.1 32 5.2 0.1 4.2 3 0 0 3 3 3 0 HEAT repeat Nipped-B_C PF12830.7 EPE33441.1 - 0.053 13.5 0.0 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus p450 PF00067.22 EPE33442.1 - 2.3e-68 231.0 0.0 3.1e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 EPE33442.1 - 2.8e-26 92.6 0.2 6.9e-26 91.4 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) RE_ApaLI PF09499.10 EPE33442.1 - 0.1 12.3 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease Methyltransf_2 PF00891.18 EPE33443.1 - 7.8e-27 93.9 0.1 1.4e-26 93.1 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 EPE33443.1 - 0.0019 18.9 0.0 0.0044 17.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE33443.1 - 0.0035 18.0 0.0 0.01 16.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE33443.1 - 0.0057 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HTH_38 PF13936.6 EPE33443.1 - 0.021 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain NUMOD1 PF07453.13 EPE33443.1 - 0.034 14.4 0.1 0.075 13.3 0.1 1.6 1 0 0 1 1 1 0 NUMOD1 domain Methyltransf_11 PF08241.12 EPE33443.1 - 0.093 13.4 0.0 0.23 12.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 EPE33443.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.6 EPE33443.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CENP-B_N PF04218.13 EPE33443.1 - 0.17 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain AMP-binding PF00501.28 EPE33445.1 - 3.2e-39 134.7 0.0 1.1e-38 133.0 0.0 1.7 1 1 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 EPE33445.1 - 3.8e-26 92.6 0.0 1.2e-25 90.9 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 EPE33445.1 - 6e-08 32.9 0.3 1.3e-07 31.9 0.3 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 EPE33445.1 - 0.0057 17.3 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family GH3 PF03321.13 EPE33445.1 - 0.039 12.8 0.0 2.5 6.8 0.0 2.2 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Abhydrolase_3 PF07859.13 EPE33446.1 - 3e-37 128.6 0.0 3.6e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EPE33446.1 - 3.8e-06 26.1 0.0 5.1e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 EPE33446.1 - 0.00032 19.7 0.0 0.0013 17.7 0.0 1.7 2 0 0 2 2 2 1 Steryl acetyl hydrolase NB-ARC PF00931.22 EPE33447.1 - 8e-16 58.0 0.0 1.6e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EPE33447.1 - 2.4e-09 37.8 2.1 2.7e-08 34.4 0.9 2.8 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EPE33447.1 - 3.4e-05 23.8 0.1 8.1e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EPE33447.1 - 0.062 13.6 0.0 0.25 11.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain COQ9 PF08511.11 EPE33447.1 - 0.12 12.2 0.2 0.3 10.9 0.2 1.7 1 0 0 1 1 1 0 COQ9 DUF4885 PF16226.5 EPE33447.1 - 0.16 11.0 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4885) tRNA-synt_2 PF00152.20 EPE33448.1 - 1e-72 244.9 0.0 2.8e-72 243.5 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 EPE33448.1 - 2e-12 46.7 0.0 3.2e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 EPE33448.1 - 1.5e-05 24.9 0.1 3.2e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Abhydrolase_3 PF07859.13 EPE33449.1 - 5.9e-39 134.1 0.0 8.9e-27 94.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 EPE33449.1 - 1.3e-07 30.9 0.1 2.8e-07 29.8 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 EPE33449.1 - 0.035 13.8 1.0 0.25 11.0 1.0 2.0 1 1 0 1 1 1 0 Putative esterase DUF2974 PF11187.8 EPE33449.1 - 0.2 11.2 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) HET PF06985.11 EPE33450.1 - 1.2e-31 110.1 1.4 1.9e-31 109.4 1.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_2 PF00891.18 EPE33451.1 - 9e-30 103.5 0.0 1.8e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EPE33451.1 - 0.00048 20.8 0.0 0.00095 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EPE33451.1 - 0.008 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EPE33451.1 - 0.038 13.5 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CheR PF01739.18 EPE33451.1 - 0.16 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain GMC_oxred_N PF00732.19 EPE33453.1 - 1.2e-33 116.7 0.0 2.7e-31 109.1 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE33453.1 - 8.7e-29 100.9 0.0 1.4e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EPE33453.1 - 0.00011 22.3 0.1 0.00031 20.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE33453.1 - 0.00029 20.0 0.0 0.00054 19.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE33453.1 - 0.00073 18.9 0.1 0.0031 16.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE33453.1 - 0.0016 17.8 0.1 0.78 8.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE33453.1 - 0.0074 15.0 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EPE33453.1 - 0.013 15.1 0.1 0.03 13.9 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EPE33453.1 - 0.016 14.3 0.1 0.024 13.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 EPE33453.1 - 0.033 13.4 0.1 0.05 12.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 EPE33453.1 - 0.079 12.3 0.2 0.14 11.5 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 EPE33453.1 - 0.14 11.8 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ebp2 PF05890.12 EPE33454.1 - 1.7e-96 322.9 18.9 1.7e-96 322.9 18.9 1.8 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF5560 PF17715.1 EPE33456.1 - 0.51 9.8 0.0 0.51 9.8 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5560) PQ-loop PF04193.14 EPE33457.1 - 1.5e-37 127.1 13.3 6.8e-19 67.4 2.4 2.7 2 0 0 2 2 2 2 PQ loop repeat WD40 PF00400.32 EPE33458.1 - 3.7e-39 132.0 25.4 8.5e-08 32.7 0.1 12.3 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.12 EPE33458.1 - 1.2e-25 89.9 0.0 1.8e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EPE33458.1 - 4.7e-20 71.7 0.0 0.026 14.8 0.0 9.3 5 2 5 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPE33458.1 - 4.7e-08 32.4 0.2 0.69 8.8 0.0 5.4 4 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EPE33458.1 - 5.2e-07 29.7 1.8 0.13 12.1 0.1 5.4 4 1 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EPE33458.1 - 0.00019 20.8 0.0 1 8.6 0.0 4.0 4 1 1 5 5 5 2 WD40-like domain Nbas_N PF15492.6 EPE33458.1 - 0.0017 17.8 0.1 4.2 6.6 0.0 3.5 3 0 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EPE33458.1 - 0.024 13.3 3.9 13 4.2 0.0 3.9 2 2 1 3 3 3 0 Nucleoporin Nup120/160 RPN1_RPN2_N PF17781.1 EPE33458.1 - 0.053 12.9 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain Septin PF00735.18 EPE33459.1 - 1.1e-113 379.2 0.2 1.5e-113 378.7 0.2 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EPE33459.1 - 1.4e-07 31.6 0.0 2.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EPE33459.1 - 2.7e-06 27.1 1.3 0.00011 21.8 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EPE33459.1 - 3.7e-06 27.0 0.1 5.8e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EPE33459.1 - 0.0021 18.3 0.4 0.0069 16.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 EPE33459.1 - 0.003 17.1 0.1 0.0052 16.3 0.1 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 EPE33459.1 - 0.0037 17.5 0.1 0.0077 16.4 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EPE33459.1 - 0.0058 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 EPE33459.1 - 0.0083 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 EPE33459.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Casc1_N PF15927.5 EPE33459.1 - 0.019 14.7 8.0 0.049 13.3 8.0 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus AAA_16 PF13191.6 EPE33459.1 - 0.029 14.7 1.0 0.08 13.3 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain Ras PF00071.22 EPE33459.1 - 0.029 13.9 0.5 0.087 12.4 0.3 1.9 2 1 0 2 2 2 0 Ras family T2SSE PF00437.20 EPE33459.1 - 0.032 13.3 0.4 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein FOXP-CC PF16159.5 EPE33459.1 - 0.034 14.8 0.7 0.12 13.0 0.7 1.9 1 0 0 1 1 1 0 FOXP coiled-coil domain KAP_NTPase PF07693.14 EPE33459.1 - 0.044 13.0 0.0 0.053 12.8 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.12 EPE33459.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EPE33459.1 - 0.075 13.5 0.0 0.28 11.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 EPE33459.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 EPE33459.1 - 0.17 11.7 0.3 5.3 6.8 0.3 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 EPE33459.1 - 0.18 12.2 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 EPE33459.1 - 0.25 11.1 0.8 13 5.5 0.1 2.7 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EPE33459.1 - 0.3 11.1 5.0 4.7 7.2 0.0 3.0 2 1 1 3 3 3 0 Dynamin family BCDHK_Adom3 PF10436.9 EPE33460.1 - 5.4e-49 166.1 0.4 1.1e-48 165.2 0.2 1.6 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EPE33460.1 - 6.2e-06 26.7 0.0 7e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1737 PF08410.10 EPE33460.1 - 0.095 12.6 0.2 6.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1737) CRAL_TRIO PF00650.20 EPE33461.1 - 3.8e-12 46.2 0.0 6e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EPE33461.1 - 0.00018 21.6 0.0 0.0004 20.5 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain BOP1NT PF08145.12 EPE33461.1 - 0.1 12.5 0.8 0.2 11.6 0.8 1.4 1 0 0 1 1 1 0 BOP1NT (NUC169) domain USP7_ICP0_bdg PF12436.8 EPE33462.1 - 1.6e-83 279.7 0.1 6.6e-81 271.2 0.0 3.6 3 1 1 4 4 4 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EPE33462.1 - 9.9e-73 244.2 2.1 1.2e-70 237.4 0.6 3.3 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 EPE33462.1 - 2.5e-47 161.5 0.9 4.7e-47 160.6 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPE33462.1 - 8.9e-19 68.2 0.1 3.3e-18 66.3 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EPE33462.1 - 5.8e-08 32.9 0.0 9.6e-07 29.0 0.0 2.7 2 1 0 2 2 2 1 MATH domain RA PF00788.23 EPE33462.1 - 0.003 18.2 0.1 0.045 14.4 0.0 3.0 4 0 0 4 4 4 1 Ras association (RalGDS/AF-6) domain SKIP_SNW PF02731.15 EPE33463.1 - 7.2e-72 240.3 4.6 7.2e-72 240.3 4.6 2.4 2 0 0 2 2 2 1 SKIP/SNW domain EMP24_GP25L PF01105.24 EPE33463.1 - 5.8e-34 117.6 1.3 5.8e-34 117.6 1.3 1.7 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD PAF-AH_p_II PF03403.13 EPE33466.1 - 2.2e-45 154.8 0.0 1.3e-44 152.3 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EPE33466.1 - 5.5e-09 35.3 0.0 3.1e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EPE33466.1 - 2.5e-06 26.8 0.0 4.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 EPE33466.1 - 0.00052 19.3 0.0 0.078 12.2 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPE33466.1 - 0.0048 17.5 0.4 0.012 16.2 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EPE33466.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family NACHT PF05729.12 EPE33467.1 - 1.3e-06 28.4 0.1 5.8e-06 26.3 0.1 2.1 2 0 0 2 2 2 1 NACHT domain DUF676 PF05057.14 EPE33467.1 - 8.9e-05 22.1 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.6 EPE33467.1 - 0.0011 19.4 0.0 0.0041 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain PGAP1 PF07819.13 EPE33467.1 - 0.0012 18.7 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein RNA_helicase PF00910.22 EPE33467.1 - 0.0092 16.4 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 EPE33467.1 - 0.013 15.8 0.0 0.11 12.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EPE33467.1 - 0.015 15.8 0.0 0.04 14.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EPE33467.1 - 0.023 15.2 0.0 0.11 13.0 0.0 2.3 2 1 0 2 2 1 0 AAA domain NB-ARC PF00931.22 EPE33467.1 - 0.067 12.4 0.0 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 EPE33467.1 - 0.095 12.5 0.1 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 EPE33467.1 - 0.099 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 EPE33467.1 - 0.15 12.3 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.7 EPE33467.1 - 0.15 12.7 0.0 0.32 11.6 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF87 PF01935.17 EPE33467.1 - 0.17 12.0 0.4 0.83 9.7 0.0 2.3 3 0 0 3 3 3 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 EPE33467.1 - 0.17 11.9 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase MFS_1 PF07690.16 EPE33468.1 - 7e-33 114.0 32.3 9.7e-33 113.5 32.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CAF1A PF12253.8 EPE33469.1 - 2e-22 79.1 4.9 2e-22 79.1 4.9 3.4 2 1 0 2 2 1 1 Chromatin assembly factor 1 subunit A ERM PF00769.19 EPE33469.1 - 0.0083 16.0 34.5 0.018 14.9 34.5 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Mitofilin PF09731.9 EPE33469.1 - 0.073 11.9 31.9 0.11 11.3 31.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF262 PF03235.14 EPE33469.1 - 0.18 11.9 6.3 0.47 10.6 6.3 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF262 Golgin_A5 PF09787.9 EPE33469.1 - 0.48 9.8 24.1 0.9 8.9 24.1 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 EPE33469.1 - 0.68 9.2 21.9 1.4 8.2 21.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 EPE33469.1 - 0.99 8.2 11.1 1.2 7.9 11.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_P83 PF05262.11 EPE33469.1 - 1.3 7.4 40.1 2.2 6.7 40.1 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Exonuc_VII_L PF02601.15 EPE33469.1 - 1.3 8.5 11.0 2.2 7.8 11.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DBINO PF13892.6 EPE33469.1 - 1.4 9.3 41.0 3.3 8.1 41.0 1.5 1 0 0 1 1 1 0 DNA-binding domain KfrA_N PF11740.8 EPE33469.1 - 1.6 9.5 26.0 4.6 8.0 26.0 1.8 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Folliculin PF11704.8 EPE33469.1 - 4.7 7.1 12.3 12 5.8 12.3 1.7 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport CNDH2_C PF16858.5 EPE33469.1 - 5.2 6.8 24.3 16 5.2 0.3 2.4 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF4778 PF16008.5 EPE33469.1 - 8.3 6.4 13.6 16 5.4 13.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Presenilin PF01080.17 EPE33469.1 - 8.6 5.0 21.5 16 4.1 21.5 1.4 1 0 0 1 1 1 0 Presenilin VirionAssem_T7 PF11653.8 EPE33472.1 - 0.053 14.1 0.7 0.066 13.7 0.7 1.1 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein HET PF06985.11 EPE33473.1 - 3.1e-21 76.3 0.0 9.6e-21 74.7 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) tRNA-synt_1e PF01406.19 EPE33475.1 - 1e-99 333.7 0.0 3.3e-99 332.0 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 EPE33475.1 - 1.5e-06 28.5 0.0 4.9e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 DALR domain tRNA-synt_1g PF09334.11 EPE33475.1 - 7.6e-05 21.6 0.4 0.17 10.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 EPE33475.1 - 0.0029 16.5 2.3 0.063 12.2 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain 40S_SA_C PF16122.5 EPE33475.1 - 0.08 14.3 8.6 0.23 12.8 8.6 1.8 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus GCD14 PF08704.10 EPE33476.1 - 1.7e-62 211.3 4.4 4.4e-43 147.7 0.2 3.8 3 2 0 3 3 3 2 tRNA methyltransferase complex GCD14 subunit Abhydrolase_2 PF02230.16 EPE33477.1 - 6.6e-15 55.5 0.0 8.2e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EPE33477.1 - 0.0088 16.7 0.3 0.011 16.3 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3759 PF12585.8 EPE33478.1 - 2.8e-40 136.2 4.4 4e-40 135.7 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) SQHop_cyclase_C PF13243.6 EPE33478.1 - 0.012 14.8 0.4 2.1 7.3 0.0 2.0 1 1 1 2 2 2 0 Squalene-hopene cyclase C-terminal domain Peptidase_M18 PF02127.15 EPE33479.1 - 2.9e-134 448.1 0.0 3.4e-134 447.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) ABM PF03992.16 EPE33480.1 - 5.3e-05 23.3 0.0 6.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase adh_short PF00106.25 EPE33481.1 - 3e-20 72.5 0.0 3.8e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE33481.1 - 2.8e-12 46.7 0.0 3.7e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE33481.1 - 0.00028 20.9 0.1 0.00058 19.8 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 EPE33481.1 - 0.0091 15.9 0.1 0.028 14.3 0.1 2.0 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 EPE33481.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Aa_trans PF01490.18 EPE33482.1 - 2.2e-79 267.1 23.5 2.6e-79 266.9 23.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spt5_N PF11942.8 EPE33482.1 - 0.22 12.5 9.5 0.49 11.4 9.5 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal YrzK PF17449.2 EPE33483.1 - 0.19 12.0 0.1 0.19 12.0 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized YrzK-like WW PF00397.26 EPE33484.1 - 1.2e-06 28.5 1.2 3.1e-06 27.2 1.2 1.8 1 0 0 1 1 1 1 WW domain WRW PF10206.9 EPE33484.1 - 0.006 16.9 0.2 0.017 15.5 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial F1F0-ATP synthase, subunit f BNIP3 PF06553.12 EPE33484.1 - 5.3 6.7 7.9 0.25 11.0 2.5 1.5 2 0 0 2 2 2 0 BNIP3 Metallophos PF00149.28 EPE33487.1 - 1.4e-36 126.9 0.1 2.2e-36 126.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1647 PF07801.11 EPE33487.1 - 0.048 13.4 0.7 2 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) bZIP_2 PF07716.15 EPE33488.1 - 5.1e-08 32.9 13.1 5.1e-08 32.9 13.1 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 EPE33488.1 - 0.23 11.6 17.1 14 5.9 17.0 2.3 1 1 0 1 1 1 0 bZIP transcription factor Herpes_UL25 PF01499.16 EPE33488.1 - 0.47 8.9 2.4 0.79 8.2 2.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Voldacs PF03517.13 EPE33489.1 - 8.5e-27 94.0 0.2 1.8e-26 92.9 0.2 1.5 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling OPT PF03169.15 EPE33490.1 - 5.4e-131 438.2 43.4 6.1e-131 438.0 43.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Sm_multidrug_ex PF06695.11 EPE33490.1 - 1.1 9.9 5.9 12 6.5 0.0 3.6 3 0 0 3 3 3 0 Putative small multi-drug export protein PLDc_2 PF13091.6 EPE33491.1 - 2.4e-15 56.6 0.0 2.9e-06 27.2 0.0 3.7 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 EPE33491.1 - 5.3e-13 48.6 0.5 2.7e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif 3Beta_HSD PF01073.19 EPE33493.1 - 1.4e-52 178.4 0.0 1.8e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPE33493.1 - 1e-28 100.4 0.0 1.2e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE33493.1 - 9.2e-22 77.9 0.0 2.1e-21 76.7 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPE33493.1 - 1.9e-14 53.5 0.2 5.4e-08 32.3 0.1 2.2 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EPE33493.1 - 4.9e-10 39.0 0.4 2.6e-09 36.6 0.4 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EPE33493.1 - 2.6e-06 27.5 0.0 3.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EPE33493.1 - 6e-05 22.3 0.0 9.1e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EPE33493.1 - 0.25 11.2 0.9 3 7.7 0.9 2.4 1 1 0 1 1 1 0 KR domain Haemagg_act PF05860.13 EPE33495.1 - 0.047 13.6 0.7 0.5 10.3 0.7 2.2 1 1 1 2 2 2 0 haemagglutination activity domain Phycoerythr_ab PF02972.14 EPE33495.1 - 0.051 13.4 2.6 6.3 6.7 0.1 3.1 1 1 2 3 3 3 0 Phycoerythrin, alpha/beta chain EZH2_N PF18601.1 EPE33495.1 - 0.17 12.2 3.5 2.3 8.6 0.4 2.2 1 1 1 2 2 2 0 EZH2 N-terminal domain DUF3382 PF11862.8 EPE33495.1 - 0.3 11.4 0.7 0.55 10.5 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Potassium_chann PF11404.8 EPE33495.1 - 1.2 9.0 8.7 1.2e+02 2.6 0.1 4.8 5 0 0 5 5 5 0 Potassium voltage-gated channel DUF3270 PF11674.8 EPE33495.1 - 3 8.1 10.2 10 6.4 0.1 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF3270) Zn_clus PF00172.18 EPE33496.1 - 2.1e-08 34.1 14.7 4.2e-08 33.2 14.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sigma70_ECF PF07638.11 EPE33496.1 - 0.11 12.4 0.0 1 9.2 0.0 2.4 3 0 0 3 3 3 0 ECF sigma factor DUF3328 PF11807.8 EPE33497.1 - 0.00012 22.0 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF202 PF02656.15 EPE33498.1 - 0.024 15.1 0.0 0.04 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Fungal_trans PF04082.18 EPE33499.1 - 1.4e-21 76.7 0.1 2.3e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPE33499.1 - 1.6e-10 40.9 7.8 0.00012 22.3 0.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE33499.1 - 6.4e-08 32.8 4.9 0.004 17.9 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPE33499.1 - 5e-05 23.5 7.9 0.029 14.8 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 EPE33499.1 - 0.0021 18.0 0.5 1.2 9.2 0.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE33499.1 - 0.028 14.7 1.4 1.5 9.2 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EPE33499.1 - 0.033 14.5 0.7 0.075 13.3 0.7 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding BolA PF01722.18 EPE33499.1 - 0.048 13.9 0.2 0.12 12.7 0.2 1.6 1 0 0 1 1 1 0 BolA-like protein Elf1 PF05129.13 EPE33499.1 - 0.057 13.5 0.6 0.13 12.3 0.6 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2_11 PF16622.5 EPE33499.1 - 0.37 10.6 4.7 2.4 8.0 1.2 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type HET PF06985.11 EPE33500.1 - 2.3e-12 47.5 9.0 1.5e-10 41.6 1.3 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_5 PF05631.14 EPE33501.1 - 3.3e-68 230.2 3.2 4.6e-68 229.7 3.2 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EPE33501.1 - 2.3e-22 79.4 15.9 3.5e-22 78.8 15.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EPE33501.1 - 3.2e-06 26.2 0.0 0.003 16.5 0.0 3.0 1 1 2 3 3 3 2 MFS_1 like family MFS_2 PF13347.6 EPE33501.1 - 1.6e-05 23.6 15.4 0.0051 15.4 7.1 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein CopD PF05425.13 EPE33501.1 - 0.94 9.9 7.8 16 6.0 0.2 3.3 3 0 0 3 3 3 0 Copper resistance protein D EXS PF03124.14 EPE33502.1 - 1.8e-99 333.2 34.2 2.2e-99 332.9 34.2 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EPE33502.1 - 4.5e-70 237.5 0.7 4.5e-70 237.5 0.7 2.1 2 0 0 2 2 2 1 SPX domain FUR PF01475.19 EPE33502.1 - 0.091 12.9 0.1 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 Ferric uptake regulator family MatE PF01554.18 EPE33503.1 - 1e-08 35.0 20.9 8.1e-05 22.3 5.9 3.8 3 1 0 3 3 3 3 MatE Polysacc_synt_C PF14667.6 EPE33503.1 - 0.0014 18.7 6.0 0.0014 18.7 6.0 4.2 4 1 1 5 5 5 1 Polysaccharide biosynthesis C-terminal domain SprT-like PF10263.9 EPE33504.1 - 0.00035 20.4 0.0 0.00066 19.5 0.0 1.5 1 0 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 EPE33504.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Effector protein APH PF01636.23 EPE33505.1 - 2.3e-11 44.1 0.0 1.9e-10 41.1 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE33505.1 - 2.9e-07 30.3 0.0 5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF5042 PF16445.5 EPE33505.1 - 0.085 11.2 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5042) DUF1679 PF07914.11 EPE33505.1 - 0.096 11.5 0.0 0.29 9.9 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) ABM PF03992.16 EPE33507.1 - 8e-06 25.9 2.6 0.012 15.7 0.4 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF1330 PF07045.11 EPE33507.1 - 0.02 15.2 0.6 1.8 9.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1330) YcgL PF05166.13 EPE33507.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 YcgL domain MFS_1 PF07690.16 EPE33508.1 - 4e-35 121.4 29.8 5.9e-35 120.8 29.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily C1_1 PF00130.22 EPE33509.1 - 0.036 13.9 3.2 0.12 12.3 3.2 1.9 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glyco_trans_1_3 PF13528.6 EPE33509.1 - 0.067 12.4 0.0 0.096 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 adh_short_C2 PF13561.6 EPE33510.1 - 1.2e-56 191.9 4.7 8.6e-56 189.1 4.7 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE33510.1 - 2.2e-32 112.1 5.7 9.2e-32 110.1 5.7 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE33510.1 - 1e-09 38.6 0.9 3.5e-08 33.6 0.2 2.1 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 EPE33510.1 - 0.0016 18.7 0.7 0.0032 17.7 0.6 1.6 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 EPE33510.1 - 0.0024 17.3 0.0 0.0061 15.9 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EPE33510.1 - 0.0054 16.2 0.2 0.11 11.9 0.1 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 EPE33510.1 - 0.062 13.8 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding PNK3P PF08645.11 EPE33510.1 - 0.065 12.9 0.0 0.25 11.0 0.0 1.8 1 1 1 2 2 2 0 Polynucleotide kinase 3 phosphatase 3HCDH_N PF02737.18 EPE33510.1 - 0.08 12.8 0.3 0.14 12.0 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EPE33510.1 - 0.086 12.8 0.4 0.38 10.7 0.1 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FLILHELTA PF10306.9 EPE33512.1 - 6.2e-34 116.3 0.1 1.6e-33 115.0 0.0 1.7 2 0 0 2 2 2 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EPE33512.1 - 0.006 17.1 0.0 0.008 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) NDK PF00334.19 EPE33513.1 - 4e-54 182.3 0.0 4.9e-54 182.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.26 EPE33514.1 - 8.3e-145 483.3 4.0 1.1e-144 482.9 4.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EPE33514.1 - 3.9e-25 87.9 0.2 1.2e-24 86.4 0.2 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 EPE33514.1 - 2e-07 31.2 0.4 7.3e-07 29.4 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) NAD_binding_10 PF13460.6 EPE33514.1 - 0.054 13.4 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Phosphonate-bd PF12974.7 EPE33515.1 - 2.2e-05 24.2 0.0 4.6e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EPE33515.1 - 0.0024 17.8 0.0 0.032 14.2 0.0 2.0 1 1 1 2 2 2 1 NMT1/THI5 like DUF3834 PF12916.7 EPE33515.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3834) UQ_con PF00179.26 EPE33516.1 - 9.2e-49 164.7 0.0 1e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPE33516.1 - 0.044 13.5 0.0 0.089 12.5 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B TP6A_N PF04406.14 EPE33517.1 - 5.5e-23 80.7 0.0 1.1e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase SQHop_cyclase_C PF13243.6 EPE33518.1 - 1.1e-48 165.9 0.1 1.7e-46 158.8 0.3 2.4 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EPE33518.1 - 2.7e-36 125.2 5.4 3.4e-32 111.7 0.9 4.3 4 1 1 5 5 5 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EPE33518.1 - 5.9e-29 99.5 4.6 1.5e-08 34.3 0.0 4.0 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 EPE33518.1 - 4.5e-05 22.9 1.9 0.21 10.9 0.1 3.9 3 1 1 5 5 5 2 Pectic acid lyase TED_complement PF07678.14 EPE33518.1 - 0.0014 17.7 3.0 0.0018 17.3 0.0 2.7 3 1 0 3 3 3 1 A-macroglobulin TED domain Beta-prism_lec PF16458.5 EPE33519.1 - 0.00012 22.1 0.2 0.00062 19.7 0.1 2.3 1 1 1 2 2 2 1 Beta-prism lectin Jacalin PF01419.17 EPE33519.1 - 0.00013 21.9 0.2 0.002 18.1 0.0 2.9 2 1 1 3 3 3 1 Jacalin-like lectin domain SGS PF05002.15 EPE33520.1 - 6.4e-32 109.5 3.9 1.6e-31 108.2 3.9 1.7 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EPE33520.1 - 7.5e-15 55.7 0.1 1.2e-14 55.1 0.1 1.3 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 EPE33520.1 - 1.2e-07 31.3 2.1 0.027 14.6 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EPE33520.1 - 3.8e-07 29.6 0.9 0.021 14.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPE33520.1 - 8.2e-06 26.0 5.6 0.0012 19.1 3.9 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EPE33520.1 - 0.0036 17.9 6.2 0.025 15.2 0.2 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPE33520.1 - 0.0038 17.9 0.4 7.3 7.7 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.14 EPE33520.1 - 0.13 13.0 5.1 7.1 7.6 1.8 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HemY_N PF07219.13 EPE33520.1 - 0.23 11.7 3.1 4.1 7.6 0.1 2.4 1 1 0 2 2 2 0 HemY protein N-terminus DUF2057 PF09829.9 EPE33520.1 - 0.49 10.5 0.0 0.49 10.5 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2057) Alpha-amylase PF00128.24 EPE33521.1 - 2.4e-10 40.5 0.0 5.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_21 PF03370.13 EPE33521.1 - 5.5e-08 33.0 0.3 1.3e-07 31.8 0.3 1.6 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EPE33521.1 - 0.0032 18.0 1.1 0.011 16.3 1.1 1.9 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) MscL PF01741.18 EPE33522.1 - 7.5e-20 71.4 0.0 9.4e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.22 EPE33522.1 - 0.0036 17.1 2.1 0.0075 16.1 2.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-BED PF02892.15 EPE33522.1 - 0.11 12.5 2.4 0.22 11.6 2.4 1.4 1 0 0 1 1 1 0 BED zinc finger COX7C PF02935.16 EPE33522.1 - 0.43 10.9 3.1 4.4 7.6 1.6 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc p450 PF00067.22 EPE33523.1 - 1.8e-48 165.5 0.0 2.1e-45 155.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Lipase_GDSL_2 PF13472.6 EPE33524.1 - 7.6e-10 39.5 0.3 3.8e-09 37.2 0.3 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE33524.1 - 8.3e-06 25.9 0.0 1.3e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RTA1 PF04479.13 EPE33526.1 - 1.9e-35 122.4 11.2 2.5e-35 122.0 11.2 1.1 1 0 0 1 1 1 1 RTA1 like protein NRIP1_repr_2 PF15688.5 EPE33527.1 - 0.013 15.4 0.1 0.019 14.9 0.1 1.1 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 2 ADH_zinc_N PF00107.26 EPE33528.1 - 2.6e-08 33.9 0.0 6.2e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE33528.1 - 1.3e-06 28.2 0.1 5.5e-06 26.2 0.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DXP_reductoisom PF02670.16 EPE33528.1 - 0.13 12.9 0.0 2.2 9.0 0.0 2.2 1 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Glyco_hydro_18 PF00704.28 EPE33529.1 - 1.3e-13 51.4 0.0 2.4e-13 50.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 MFS_1 PF07690.16 EPE33531.1 - 8.8e-35 120.3 34.4 8.8e-35 120.3 34.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE33531.1 - 2.3e-12 46.5 1.4 2.3e-12 46.5 1.4 2.4 3 1 0 3 3 3 1 Sugar (and other) transporter DUF4231 PF14015.6 EPE33531.1 - 8 7.0 10.1 3.2 8.3 0.1 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF4231) DUF3584 PF12128.8 EPE33534.1 - 0.0097 13.5 1.9 0.013 13.0 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 EPE33534.1 - 0.0098 15.9 3.3 0.019 15.0 3.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 EPE33534.1 - 0.072 13.1 4.9 0.14 12.2 4.9 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EPE33534.1 - 0.15 10.9 3.9 0.26 10.1 3.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Fungal_TACC PF12709.7 EPE33534.1 - 0.66 10.5 3.2 6.4 7.3 0.8 2.5 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins TMF_TATA_bd PF12325.8 EPE33534.1 - 0.67 10.2 4.9 0.78 10.0 3.3 1.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding XhlA PF10779.9 EPE33534.1 - 9.1 6.6 7.5 2.3 8.5 1.2 2.3 1 1 1 2 2 2 0 Haemolysin XhlA APG6_N PF17675.1 EPE33534.1 - 9.5 6.8 8.5 48 4.5 8.5 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Aida_N PF08910.10 EPE33535.1 - 0.0091 16.4 4.6 0.0091 16.4 4.6 2.6 2 0 0 2 2 2 1 Aida N-terminus Pro-rich_19 PF15455.6 EPE33535.1 - 0.13 11.4 4.8 1.5 7.9 0.1 3.3 1 1 1 3 3 3 0 Proline-rich 19 DUF3552 PF12072.8 EPE33535.1 - 9.9 5.5 75.9 0.47 9.8 13.9 6.0 1 1 4 6 6 6 0 Domain of unknown function (DUF3552) DIOX_N PF14226.6 EPE33537.1 - 0.0099 16.6 0.0 0.019 15.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPE33537.1 - 0.025 15.1 0.0 0.053 14.0 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Allantoicase PF03561.15 EPE33538.1 - 8.2e-92 304.7 0.1 3.1e-46 156.9 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Amidohydro_1 PF01979.20 EPE33539.1 - 2.8e-22 79.5 0.0 4.4e-22 78.9 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPE33539.1 - 1.5e-10 41.2 0.0 8.7e-06 25.5 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family IU_nuc_hydro PF01156.19 EPE33540.1 - 1.5e-74 251.4 0.0 1.8e-74 251.1 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase AA_permease_2 PF13520.6 EPE33541.1 - 5.6e-68 229.7 47.0 7.1e-68 229.4 47.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE33541.1 - 4.5e-24 84.9 41.8 6.3e-24 84.4 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3341 PF11821.8 EPE33541.1 - 4.3 6.9 6.8 1.4 8.6 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) His_Phos_1 PF00300.22 EPE33542.1 - 5.4e-22 78.4 0.0 6.5e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AMP-binding PF00501.28 EPE33543.1 - 6e-72 242.5 0.0 7.8e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE33543.1 - 1.7e-16 60.9 0.0 4.2e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ketoacyl-synt PF00109.26 EPE33544.1 - 2.8e-69 233.5 0.0 5.7e-69 232.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EPE33544.1 - 2.3e-58 197.8 0.0 3.7e-58 197.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EPE33544.1 - 1.7e-54 184.5 0.2 3.3e-54 183.5 0.2 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EPE33544.1 - 1.4e-47 162.8 0.0 2.5e-47 161.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE33544.1 - 2.8e-35 120.9 0.2 8.6e-35 119.3 0.2 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EPE33544.1 - 1.8e-20 73.5 0.0 4.9e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EPE33544.1 - 2.2e-10 40.3 0.1 5.1e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE33544.1 - 3.4e-06 26.8 0.0 8.2e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 EPE33544.1 - 4.3e-05 23.0 0.1 8.6e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.15 EPE33544.1 - 0.0021 17.3 0.0 0.0035 16.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_zinc_N_2 PF13602.6 EPE33544.1 - 0.0056 17.7 0.0 0.034 15.2 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 3Beta_HSD PF01073.19 EPE33544.1 - 0.052 12.6 0.1 0.12 11.4 0.1 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 EPE33544.1 - 0.075 13.4 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site ACP_syn_III PF08545.10 EPE33544.1 - 0.12 12.2 0.6 0.35 10.8 0.6 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SCO1-SenC PF02630.14 EPE33544.1 - 0.13 12.2 0.0 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 SCO1/SenC Rhomboid PF01694.22 EPE33545.1 - 6.7e-32 110.6 12.9 6.7e-32 110.6 12.9 2.0 2 0 0 2 2 2 1 Rhomboid family SCHIP-1 PF10148.9 EPE33546.1 - 0.11 12.0 1.9 0.19 11.3 1.9 1.4 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Terminase_4 PF05119.12 EPE33546.1 - 0.93 10.0 4.5 0.31 11.5 0.4 2.2 2 0 0 2 2 2 0 Phage terminase, small subunit MFS_1 PF07690.16 EPE33550.1 - 1.2e-47 162.6 59.7 1.2e-47 162.5 57.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE33550.1 - 4.6e-17 61.7 14.2 2e-16 59.5 13.9 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPE33550.1 - 9.3e-13 47.8 12.6 9.3e-13 47.8 12.6 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter Sulfatase PF00884.23 EPE33551.1 - 3.2e-54 184.4 0.0 4e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 EPE33551.1 - 4.5e-27 93.6 0.4 9.5e-27 92.6 0.4 1.6 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 EPE33551.1 - 2.6e-09 37.2 0.0 2.4e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 EPE33551.1 - 0.018 15.0 0.1 1.3 9.0 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function DUF4976 PF16347.5 EPE33551.1 - 0.022 15.0 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 EPE33551.1 - 0.082 13.6 0.1 0.47 11.2 0.1 2.1 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase Peptidase_M9_N PF08453.10 EPE33551.1 - 0.15 11.8 0.0 3.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M9 N-terminal FSH1 PF03959.13 EPE33552.1 - 1.7e-29 103.0 0.0 1.4e-28 100.0 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.26 EPE33553.1 - 2e-69 234.0 0.0 3.4e-69 233.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EPE33553.1 - 3.3e-62 209.6 0.0 8.5e-62 208.3 0.0 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EPE33553.1 - 7e-50 170.3 0.0 1.5e-49 169.2 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EPE33553.1 - 8.6e-48 163.1 0.0 1.4e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EPE33553.1 - 5.7e-36 123.1 0.1 1.5e-35 121.7 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EPE33553.1 - 5e-18 65.7 0.0 1.6e-17 64.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EPE33553.1 - 4.8e-17 62.2 0.0 4.2e-16 59.1 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE33553.1 - 2.3e-16 61.1 0.0 1.7e-14 55.0 0.0 3.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EPE33553.1 - 1.3e-15 57.8 0.0 1.5e-14 54.4 0.0 2.6 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EPE33553.1 - 2.8e-14 53.0 0.3 1.7e-12 47.2 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 EPE33553.1 - 8.4e-11 42.0 0.0 2e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE33553.1 - 3.6e-10 40.4 0.0 1.3e-09 38.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE33553.1 - 4.2e-10 39.6 0.0 1.7e-09 37.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE33553.1 - 9.7e-10 39.0 0.2 6.4e-09 36.4 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.12 EPE33553.1 - 2.8e-06 27.2 0.1 6.2e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.6 EPE33553.1 - 1e-05 25.2 0.2 6.8e-05 22.5 0.0 2.4 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase SAT PF16073.5 EPE33553.1 - 2.1e-05 24.4 0.1 6e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 EPE33553.1 - 6.4e-05 23.2 0.0 0.00021 21.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.18 EPE33553.1 - 0.0004 19.8 0.1 0.0018 17.7 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Glycos_transf_N PF04413.16 EPE33553.1 - 0.044 13.4 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Methyltransf_2 PF00891.18 EPE33553.1 - 0.078 12.3 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase domain YjeF_N PF03853.15 EPE33553.1 - 0.08 12.8 0.2 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 YjeF-related protein N-terminus PALP PF00291.25 EPE33553.1 - 0.086 12.2 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme ATP13 PF12921.7 EPE33554.1 - 7.5e-24 83.8 0.1 1.5e-23 82.8 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.6 EPE33554.1 - 8.5e-07 29.1 4.3 0.0097 16.1 0.1 2.9 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 EPE33554.1 - 1.1e-06 28.6 0.0 6.7e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.20 EPE33554.1 - 0.43 10.9 7.2 8.3 6.9 0.0 4.1 4 0 0 4 4 4 0 PPR repeat LSM PF01423.22 EPE33555.1 - 5.3e-18 64.5 0.2 1.7e-17 62.8 0.2 1.7 1 1 0 1 1 1 1 LSM domain SLD5_C PF16922.5 EPE33555.1 - 0.054 13.7 0.3 0.1 12.8 0.3 1.5 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus HydF_dimer PF18128.1 EPE33555.1 - 0.06 13.4 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Hydrogen maturase F dimerization domain GTP_EFTU PF00009.27 EPE33556.1 - 8.7e-19 67.8 0.0 1.5e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EPE33556.1 - 2.1e-10 40.8 1.6 1.4e-09 38.2 1.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EPE33556.1 - 5.8e-05 23.4 0.0 0.00016 21.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain RsgA_GTPase PF03193.16 EPE33556.1 - 0.0015 18.5 0.3 2.2 8.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EPE33556.1 - 0.0056 16.7 0.2 0.016 15.3 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EPE33556.1 - 0.019 14.7 0.9 0.6 9.8 0.1 3.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Kinetochor_Ybp2 PF08568.10 EPE33557.1 - 4.6e-125 418.5 0.3 6e-125 418.2 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin DctP PF03480.13 EPE33557.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 GEN1_C PF18380.1 EPE33557.1 - 0.24 12.3 1.8 0.49 11.3 0.4 2.3 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain CMD PF02627.20 EPE33558.1 - 0.08 13.0 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family Dsh_C PF12316.8 EPE33561.1 - 0.9 9.9 11.9 1.8 9.0 11.9 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal zf-C2H2_4 PF13894.6 EPE33562.1 - 2.8e-09 37.0 26.8 0.13 13.1 1.5 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2 PF00096.26 EPE33562.1 - 4.9e-07 29.9 28.1 0.02 15.3 3.0 5.5 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-met PF12874.7 EPE33562.1 - 0.00059 20.1 19.9 0.031 14.7 1.1 5.1 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EPE33562.1 - 0.03 14.6 25.2 0.68 10.3 2.5 4.7 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EPE33562.1 - 0.042 14.1 1.8 0.042 14.1 1.8 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_4 PF13717.6 EPE33562.1 - 0.1 12.5 2.7 9.8 6.2 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-MYST PF17772.1 EPE33562.1 - 0.13 11.9 0.2 0.13 11.9 0.2 2.1 2 0 0 2 2 2 0 MYST family zinc finger domain zf-C2H2_12 PF18658.1 EPE33562.1 - 0.14 11.7 1.8 2.2 7.9 0.6 2.9 2 1 1 3 3 3 0 Zinc-finger C2H2-type zf-C2H2_2 PF12756.7 EPE33562.1 - 0.75 10.2 20.8 4.9 7.6 1.5 4.7 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 EPE33562.1 - 3.5 8.0 12.7 0.52 10.6 1.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc ribbon DHHC PF01529.20 EPE33563.1 - 2.6e-38 131.2 7.7 2.6e-38 131.2 7.7 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4064 PF13273.6 EPE33563.1 - 0.46 10.8 2.7 0.53 10.6 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DZR PF12773.7 EPE33563.1 - 1.8 8.6 10.0 4.8 7.3 10.0 1.6 1 1 0 1 1 1 0 Double zinc ribbon UQ_con PF00179.26 EPE33564.1 - 1.7e-18 66.6 0.0 2.7e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EPE33564.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 RWD domain SGL PF08450.12 EPE33565.1 - 9.7e-05 22.1 0.0 0.00024 20.8 0.0 1.6 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Zn_clus PF00172.18 EPE33566.1 - 6e-06 26.3 11.7 1.1e-05 25.4 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE33566.1 - 7.5e-06 25.0 5.6 8.7e-05 21.5 1.1 2.5 3 0 0 3 3 3 2 Fungal specific transcription factor domain RTA1 PF04479.13 EPE33568.1 - 0.0039 16.8 0.9 0.0039 16.8 0.9 1.8 2 0 0 2 2 2 1 RTA1 like protein Zip PF02535.22 EPE33568.1 - 0.038 13.2 0.9 0.11 11.7 0.2 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter TMCCDC2 PF15844.5 EPE33568.1 - 4.7 7.1 5.4 0.89 9.5 0.3 2.0 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 MAPEG PF01124.18 EPE33568.1 - 9.6 6.1 8.8 5.7 6.8 0.7 3.3 3 1 0 3 3 3 0 MAPEG family DUF4387 PF14330.6 EPE33569.1 - 8.5e-35 119.4 0.0 1.6e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) AtuA PF07287.11 EPE33569.1 - 6.7e-11 41.5 0.0 1.2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA MFS_1 PF07690.16 EPE33570.1 - 1.6e-25 89.8 28.0 2.1e-25 89.4 28.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.18 EPE33571.1 - 1.8e-07 31.2 10.3 3.6e-07 30.2 8.7 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE33571.1 - 0.00072 18.7 1.6 0.0014 17.7 1.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 EPE33575.1 - 1.4e-33 116.4 0.0 1.7e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 EPE33576.1 - 1.7e-08 33.7 0.2 2e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE33576.1 - 1.2e-05 25.3 12.7 2e-05 24.6 12.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 EPE33577.1 - 1.1e-49 169.5 0.0 2e-49 168.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF2600 PF10776.9 EPE33577.1 - 0.2 10.5 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) p450 PF00067.22 EPE33578.1 - 1.2e-20 73.7 0.0 2.3e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EPE33579.1 - 6.6e-34 117.4 0.1 7.7e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 HET PF06985.11 EPE33580.1 - 5.3e-31 107.9 0.1 7.9e-31 107.4 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PAN_4 PF14295.6 EPE33581.1 - 0.00024 21.0 0.2 0.00063 19.6 0.2 1.8 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 EPE33581.1 - 0.0063 16.6 0.1 0.015 15.4 0.1 1.6 1 0 0 1 1 1 1 PAN-like domain YpzI PF14140.6 EPE33582.1 - 0.0079 15.9 5.5 11 5.9 0.1 3.6 3 0 0 3 3 3 3 YpzI-like protein Excalibur PF05901.11 EPE33582.1 - 1.3 9.7 3.6 1.8e+02 2.8 0.0 4.0 4 0 0 4 4 4 0 Excalibur calcium-binding domain CorA PF01544.18 EPE33584.1 - 9.6e-31 107.2 5.5 1.2e-27 97.0 1.1 2.3 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein PrgI PF12666.7 EPE33584.1 - 0.31 11.8 2.0 0.62 10.8 2.0 1.4 1 0 0 1 1 1 0 PrgI family protein CAP59_mtransfer PF11735.8 EPE33585.1 - 1.1e-65 221.6 0.0 1.6e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CorA PF01544.18 EPE33587.1 - 0.025 13.9 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CdhC PF03598.15 EPE33587.1 - 0.19 11.6 0.5 0.47 10.3 0.2 1.8 2 0 0 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit TrkH PF02386.16 EPE33589.1 - 8.2e-21 74.0 10.7 6e-20 71.2 1.5 2.1 2 0 0 2 2 2 2 Cation transport protein Ion_trans_2 PF07885.16 EPE33589.1 - 1.2 9.2 9.1 0.17 11.8 4.5 2.0 2 0 0 2 2 2 0 Ion channel TrkH PF02386.16 EPE33590.1 - 7.7e-55 186.3 1.4 1e-54 185.9 1.4 1.0 1 0 0 1 1 1 1 Cation transport protein SAYSvFN PF10260.9 EPE33590.1 - 0.017 15.0 0.7 0.059 13.3 0.7 1.9 1 0 0 1 1 1 0 Uncharacterized conserved domain (SAYSvFN) DUF1891 PF09004.10 EPE33590.1 - 0.067 12.8 0.3 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) DNA_pol_B PF00136.21 EPE33591.1 - 4.2e-146 487.3 1.5 6.5e-146 486.7 1.0 1.5 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EPE33591.1 - 1.9e-79 267.2 0.3 3.6e-79 266.4 0.3 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EPE33591.1 - 4.8e-18 65.4 7.3 1.3e-17 64.0 7.3 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 EPE33591.1 - 0.00017 21.4 0.0 0.00051 19.8 0.0 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EPE33591.1 - 0.0043 17.1 0.2 0.023 14.7 0.2 2.2 1 1 0 1 1 1 1 RNase_H superfamily C1_1 PF00130.22 EPE33591.1 - 3.5 7.6 9.6 4.6 7.2 0.8 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Chitin_synth_1 PF01644.17 EPE33592.1 - 4.9e-67 225.0 0.0 7.4e-67 224.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EPE33592.1 - 5.4e-26 90.3 0.0 1.2e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EPE33592.1 - 1.1e-21 77.1 1.0 3e-18 65.7 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EPE33592.1 - 3.9e-12 46.5 0.1 3.9e-12 46.5 0.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EPE33592.1 - 5.8e-06 26.3 0.0 1.2e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 GST_N PF02798.20 EPE33593.1 - 2e-15 56.9 0.0 3e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPE33593.1 - 2.1e-14 53.7 0.0 3.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EPE33593.1 - 2.1e-14 53.5 0.0 3.4e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EPE33593.1 - 1.9e-11 44.1 0.0 3.5e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EPE33593.1 - 1.9e-07 31.2 0.0 3.3e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPE33593.1 - 1.7e-05 24.7 0.0 3.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-NOSIP PF15906.5 EPE33593.1 - 0.031 14.4 0.1 0.4 10.9 0.0 2.6 2 1 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein zf-C2HE PF16278.5 EPE33594.1 - 5.2e-20 71.7 0.1 1.2e-19 70.5 0.1 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 EPE33594.1 - 1.3e-15 57.9 4.0 1.3e-14 54.7 4.0 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EPE33594.1 - 6.3e-14 52.5 1.0 1.5e-13 51.3 1.0 1.6 1 1 0 1 1 1 1 HIT domain Gp37 PF09646.10 EPE33594.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Gp37 protein Bac_rhamnosid6H PF17389.2 EPE33595.1 - 1.1e-13 51.2 0.8 3.5e-12 46.2 0.3 2.4 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain HA2 PF04408.23 EPE33596.1 - 7.7e-17 61.5 1.7 1.6e-16 60.5 0.0 2.5 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EPE33596.1 - 9.2e-15 55.0 0.1 5.1e-14 52.6 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RWD PF05773.22 EPE33596.1 - 3.8e-13 49.7 0.0 7.9e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 RWD domain OB_NTP_bind PF07717.16 EPE33596.1 - 6.2e-13 48.9 0.0 1.3e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EPE33596.1 - 2e-09 37.5 0.2 4.8e-09 36.2 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase IHABP4_N PF16174.5 EPE33596.1 - 0.00077 20.1 0.0 0.0027 18.3 0.0 2.0 1 0 0 1 1 1 1 Intracellular hyaluronan-binding protein 4 N-terminal AAA_22 PF13401.6 EPE33596.1 - 0.00084 19.6 1.6 0.0047 17.2 1.6 2.2 1 1 0 1 1 1 1 AAA domain dsRBD2 PF17842.1 EPE33596.1 - 0.0023 18.1 0.1 0.0051 17.0 0.1 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding domain 2 T2SSE PF00437.20 EPE33596.1 - 0.0025 16.9 0.0 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 EPE33596.1 - 0.0058 16.4 0.1 0.21 11.3 0.1 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein DND1_DSRM PF14709.7 EPE33596.1 - 0.0091 16.2 0.2 0.036 14.3 0.1 2.2 2 0 0 2 2 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 ATPase PF06745.13 EPE33596.1 - 0.019 14.3 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 EPE33596.1 - 0.046 13.5 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EPE33596.1 - 0.14 12.7 0.0 0.14 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF3632 PF12311.8 EPE33597.1 - 7.5e-17 62.3 4.7 1.1e-16 61.7 4.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) LOR PF04525.12 EPE33599.1 - 0.0046 16.6 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 LURP-one-related Mersacidin PF16934.5 EPE33600.1 - 0.99 9.2 9.7 5.6 6.8 6.2 3.1 3 0 0 3 3 3 0 Two-component Enterococcus faecalis cytolysin (EFC) MBOAT_2 PF13813.6 EPE33601.1 - 4.2e-15 55.8 6.4 4.2e-15 55.8 6.4 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family DUF2934 PF11154.8 EPE33602.1 - 0.095 12.4 0.4 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) Tombus_P19 PF03220.13 EPE33602.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.0 1 0 0 1 1 1 0 Tombusvirus P19 core protein CHZ PF09649.10 EPE33603.1 - 0.00018 20.9 2.7 0.0057 16.1 0.0 2.8 2 0 0 2 2 2 2 Histone chaperone domain CHZ Zn_clus PF00172.18 EPE33603.1 - 0.00072 19.6 14.9 0.0012 18.9 14.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.23 EPE33604.1 - 2.2e-44 150.3 0.1 3.8e-44 149.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EPE33604.1 - 1.3e-36 125.3 0.0 3.4e-36 123.9 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Mito_carr PF00153.27 EPE33605.1 - 1e-72 240.1 0.1 1.3e-24 86.0 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.6 EPE33605.1 - 5.1e-14 50.9 3.4 1.5e-06 27.6 0.2 5.5 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 EPE33605.1 - 1.1e-13 51.4 4.9 2.1e-07 31.3 0.8 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 EPE33605.1 - 2.1e-12 45.6 6.9 1.5e-06 27.3 0.1 5.4 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 EPE33605.1 - 1.2e-06 28.2 1.1 14 5.6 0.0 5.6 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 EPE33605.1 - 5e-06 25.8 1.9 0.00027 20.3 0.2 3.6 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 EPE33605.1 - 0.019 15.2 0.0 3.7 8.0 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain FAD_binding_3 PF01494.19 EPE33606.1 - 4.6e-18 65.6 0.0 1e-08 34.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EPE33606.1 - 5.6e-10 39.3 1.1 0.0003 20.5 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE33606.1 - 5.1e-09 35.8 0.0 0.00052 19.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE33606.1 - 2.8e-08 33.2 0.3 2.8e-07 29.9 0.3 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 EPE33606.1 - 6.8e-08 31.6 0.8 2.7e-07 29.6 0.8 1.8 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 EPE33606.1 - 3.6e-05 23.2 0.4 0.007 15.7 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EPE33606.1 - 7.4e-05 23.2 0.3 0.09 13.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE33606.1 - 9.6e-05 21.6 0.4 0.00022 20.5 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EPE33606.1 - 0.0002 21.5 0.4 0.00048 20.3 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EPE33606.1 - 0.0024 16.8 0.5 0.016 14.1 0.1 2.1 1 1 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EPE33606.1 - 0.0041 16.4 0.0 0.029 13.6 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EPE33606.1 - 0.0077 15.3 0.6 0.015 14.4 0.4 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EPE33606.1 - 0.037 13.3 0.3 0.058 12.6 0.3 1.3 1 0 0 1 1 1 0 Thi4 family RNA_pol_Rpc4 PF05132.14 EPE33607.1 - 1.2e-32 113.4 0.6 1.2e-32 113.4 0.6 3.8 3 2 1 4 4 4 1 RNA polymerase III RPC4 RNF220 PF15926.5 EPE33607.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.6 2 1 1 3 3 3 0 E3 ubiquitin-protein ligase RNF220 DUF1996 PF09362.10 EPE33608.1 - 2.8e-82 276.3 0.2 3.3e-82 276.0 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) HET PF06985.11 EPE33609.1 - 1.9e-24 86.7 0.1 3.2e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FMO-like PF00743.19 EPE33611.1 - 1.5e-19 69.8 0.1 7.6e-17 60.9 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EPE33611.1 - 1.9e-19 70.0 0.0 5.1e-18 65.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPE33611.1 - 1.1e-15 57.7 0.0 1.6e-12 47.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPE33611.1 - 1.6e-12 47.3 0.0 5.7e-09 35.6 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EPE33611.1 - 2.6e-08 34.3 0.1 0.012 16.2 0.1 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EPE33611.1 - 6.5e-08 32.1 0.3 0.00079 18.8 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EPE33611.1 - 1e-06 28.3 0.1 0.0016 17.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EPE33611.1 - 1.3e-06 28.5 0.0 7.3e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EPE33611.1 - 5.5e-05 22.0 0.0 0.0063 15.3 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_9 PF13454.6 EPE33611.1 - 8e-05 22.7 0.2 0.76 9.8 0.0 3.4 2 1 0 3 3 3 2 FAD-NAD(P)-binding GIDA PF01134.22 EPE33611.1 - 0.00012 21.3 0.2 0.3 10.1 0.0 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A IlvN PF07991.12 EPE33611.1 - 0.00017 21.2 0.1 0.0036 16.9 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 EPE33611.1 - 0.00022 21.8 0.0 3.1 8.5 0.1 3.4 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 EPE33611.1 - 0.00023 21.4 0.2 0.082 13.2 0.0 2.6 3 0 0 3 3 2 1 TrkA-N domain Shikimate_DH PF01488.20 EPE33611.1 - 0.0003 20.9 0.1 0.44 10.6 0.1 2.9 4 0 0 4 4 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 EPE33611.1 - 0.00037 19.8 0.6 0.081 12.2 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EPE33611.1 - 0.00084 19.3 0.4 0.12 12.2 0.3 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EPE33611.1 - 0.0011 18.2 0.1 0.017 14.2 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 EPE33611.1 - 0.0012 19.3 0.0 0.21 12.1 0.1 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EPE33611.1 - 0.0017 17.5 0.0 0.22 10.5 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.24 EPE33611.1 - 0.0017 18.0 0.7 0.041 13.5 0.0 2.9 3 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EPE33611.1 - 0.0033 16.8 0.1 0.19 11.1 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.16 EPE33611.1 - 0.018 14.7 0.0 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 EPE33611.1 - 0.028 13.9 0.1 8.4 5.8 0.1 2.3 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_2 PF03446.15 EPE33611.1 - 0.03 14.5 0.2 1.8 8.7 0.2 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Thi4 PF01946.17 EPE33611.1 - 0.043 13.1 0.2 6.4 5.9 0.0 3.1 3 0 0 3 3 3 0 Thi4 family XdhC_C PF13478.6 EPE33611.1 - 0.063 13.8 0.0 3 8.4 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain DUF4962 PF16332.5 EPE33611.1 - 0.14 10.6 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) AdoHcyase_NAD PF00670.21 EPE33611.1 - 0.15 12.1 0.9 1.9 8.5 0.4 2.5 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EPE33611.1 - 0.17 11.8 0.3 0.98 9.4 0.1 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sugar_tr PF00083.24 EPE33612.1 - 1.8e-97 327.1 17.2 2.1e-97 326.8 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE33612.1 - 5.3e-22 78.2 50.8 5.2e-20 71.7 23.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3021 PF11457.8 EPE33612.1 - 0.66 10.3 23.5 0.3 11.4 9.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3021) Fungal_trans PF04082.18 EPE33613.1 - 2.8e-10 39.7 1.8 3.9e-10 39.2 1.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.13 EPE33614.1 - 2.2e-33 115.8 0.0 2.5e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE33614.1 - 8.7e-09 35.5 0.0 1.4e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE33614.1 - 7.1e-05 22.4 0.1 0.00014 21.4 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EPE33614.1 - 0.0025 18.1 0.0 0.0044 17.3 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EPE33614.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PQ-loop PF04193.14 EPE33618.1 - 1.1e-31 108.4 16.7 9.5e-16 57.3 6.2 3.2 2 1 1 3 3 3 2 PQ loop repeat CEP1-DNA_bind PF09287.10 EPE33618.1 - 0.15 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 CEP-1, DNA binding PAF-AH_p_II PF03403.13 EPE33621.1 - 4e-14 51.9 0.0 3.3e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.7 EPE33621.1 - 6.8e-05 22.7 0.3 0.015 15.0 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EPE33621.1 - 0.00037 19.5 0.0 0.00073 18.5 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 EPE33621.1 - 0.0016 19.1 0.2 0.0027 18.4 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE33621.1 - 0.004 16.4 0.0 0.44 9.8 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 EPE33621.1 - 0.011 14.8 0.3 0.17 10.9 0.3 2.1 1 1 0 1 1 1 0 Chlorophyllase Abhydrolase_1 PF00561.20 EPE33621.1 - 0.13 11.8 0.0 14 5.3 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 EPE33622.1 - 8.5e-11 41.3 0.1 6.9e-06 25.1 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Fox-1_C PF12414.8 EPE33622.1 - 0.17 12.3 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 Calcitonin gene-related peptide regulator C terminal Dynamin_N PF00350.23 EPE33623.1 - 1.9e-43 148.4 0.0 3.4e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EPE33623.1 - 5.8e-13 48.7 0.0 6.5e-11 42.0 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EPE33623.1 - 3.4e-05 23.9 0.0 0.00027 21.0 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EPE33623.1 - 0.029 14.8 0.6 0.28 11.5 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 EPE33623.1 - 0.042 13.7 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EPE33623.1 - 0.1 12.3 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EPE33623.1 - 0.13 12.5 1.0 1.3 9.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain GATase_4 PF13230.6 EPE33624.1 - 6.9e-14 51.4 0.0 7.1e-12 44.8 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EPE33624.1 - 5.4e-08 33.1 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Cation_efflux PF01545.21 EPE33625.1 - 1.1e-11 44.8 13.5 1.5e-11 44.4 13.5 1.1 1 0 0 1 1 1 1 Cation efflux family MSP1a PF11670.8 EPE33625.1 - 8.8 5.5 8.4 9.9 5.4 0.5 2.6 2 1 1 3 3 3 0 Major surface protein 1a (MSP1a) PIG-Y PF15159.6 EPE33626.1 - 2e-22 79.8 9.0 3.1e-22 79.3 9.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y LIAS_N PF16881.5 EPE33626.1 - 0.13 12.7 0.1 0.2 12.1 0.1 1.2 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family DUF1218 PF06749.12 EPE33626.1 - 0.19 12.3 2.5 3 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Sigma70_r2 PF04542.14 EPE33627.1 - 0.02 14.7 0.0 0.31 10.8 0.0 2.7 1 1 1 2 2 2 0 Sigma-70 region 2 AAA PF00004.29 EPE33628.1 - 1.2e-15 58.1 0.0 2.7e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE33628.1 - 0.0058 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPE33628.1 - 0.018 15.3 1.9 0.13 12.5 1.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EPE33628.1 - 0.021 15.0 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EPE33628.1 - 0.045 13.8 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EPE33628.1 - 0.053 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.6 EPE33628.1 - 0.061 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EPE33628.1 - 0.07 13.5 0.1 0.28 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain VirDNA-topo-I_N PF09266.10 EPE33628.1 - 0.077 13.2 0.1 0.24 11.6 0.1 1.8 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal Glyco_hydro_11 PF00457.17 EPE33629.1 - 5.1e-83 277.1 18.9 5.9e-83 276.9 18.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Sel_put PF04328.13 EPE33631.1 - 0.065 13.3 0.7 0.15 12.1 0.7 1.6 1 0 0 1 1 1 0 Selenoprotein, putative DUF2014 PF09427.10 EPE33631.1 - 0.069 12.5 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) TraI PF07057.11 EPE33631.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 DNA helicase TraI Vfa1 PF08432.10 EPE33631.1 - 0.13 12.5 7.5 1.3 9.3 0.5 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 ADIP PF11559.8 EPE33631.1 - 3.1 7.9 7.4 0.17 12.0 1.8 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding VCBS PF13517.6 EPE33632.1 - 2.9e-29 101.4 53.0 8.5e-10 39.1 1.6 7.1 4 2 4 8 8 8 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 EPE33632.1 - 2.9e-15 57.1 0.1 7.1e-15 55.9 0.1 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.23 EPE33632.1 - 9.7e-09 35.2 33.0 0.0026 17.8 0.1 7.3 7 0 0 7 7 7 5 FG-GAP repeat TcdB_toxin_midN PF12256.8 EPE33632.1 - 1.2e-08 34.5 13.5 0.53 9.6 0.0 6.6 3 3 4 7 7 7 4 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL PF00657.22 EPE33632.1 - 1.3e-08 35.0 0.0 2.1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PliI PF16743.5 EPE33632.1 - 0.0019 17.9 0.2 3.6 7.4 0.0 4.2 4 0 0 4 4 4 1 Periplasmic lysozyme inhibitor of I-type lysozyme Lipase_GDSL_3 PF14606.6 EPE33632.1 - 0.0067 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family BBS2_Mid PF14783.6 EPE33632.1 - 0.35 10.9 1.1 15 5.7 0.0 3.5 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Dockerin_1 PF00404.18 EPE33632.1 - 0.88 9.8 15.8 4.9 7.4 0.1 5.5 6 0 0 6 6 6 0 Dockerin type I domain NmrA PF05368.13 EPE33634.1 - 1.4e-05 24.8 0.0 3.4e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family POT1PC PF16686.5 EPE33636.1 - 1.7e-34 118.9 0.2 5.1e-32 110.9 0.1 2.6 2 0 0 2 2 2 2 ssDNA-binding domain of telomere protection protein Arm PF00514.23 EPE33637.1 - 3.9e-96 312.5 17.8 8.2e-14 51.1 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EPE33637.1 - 4e-27 94.5 2.9 4.9e-27 94.2 0.7 2.2 2 0 0 2 2 2 1 Importin beta binding domain HEAT_EZ PF13513.6 EPE33637.1 - 5.2e-22 77.9 8.8 1.6e-08 34.8 0.1 6.4 5 1 1 6 6 6 4 HEAT-like repeat Arm_3 PF16186.5 EPE33637.1 - 5.9e-21 73.8 2.3 1.3e-20 72.7 2.3 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_2 PF13646.6 EPE33637.1 - 1.3e-20 73.6 0.8 2.4e-09 37.5 0.0 5.3 1 1 5 6 6 6 4 HEAT repeats HEAT PF02985.22 EPE33637.1 - 2.9e-18 64.4 2.0 3.2e-05 23.8 0.0 7.3 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 EPE33637.1 - 1.3e-08 34.6 0.0 0.0012 18.3 0.0 3.9 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 EPE33637.1 - 1.9e-06 26.8 0.0 0.00027 19.6 0.0 2.3 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 EPE33637.1 - 9.9e-06 25.7 0.0 0.62 10.2 0.0 4.4 3 2 2 5 5 5 2 V-ATPase subunit H Cnd1 PF12717.7 EPE33637.1 - 0.00063 19.8 0.0 0.99 9.4 0.1 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 EPE33637.1 - 0.003 17.8 3.6 1.9 8.8 0.0 4.5 3 2 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 NopRA1 PF16201.5 EPE33637.1 - 0.01 15.4 0.0 5.6 6.5 0.0 3.7 2 1 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Mo25 PF08569.11 EPE33637.1 - 0.034 13.5 0.0 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 Mo25-like HEAT_PBS PF03130.16 EPE33637.1 - 0.041 14.6 6.6 1.7 9.6 0.3 4.8 5 1 0 5 5 4 0 PBS lyase HEAT-like repeat Glycos_trans_3N PF02885.17 EPE33637.1 - 0.065 13.1 0.0 33 4.4 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain SPATA9 PF15824.5 EPE33637.1 - 0.14 11.4 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 NUSAP PF16006.5 EPE33637.1 - 6.7 6.4 6.3 9.5 5.9 6.3 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein ETX_MTX2 PF03318.13 EPE33638.1 - 0.00067 19.5 22.6 0.00076 19.3 20.3 2.3 2 1 0 2 2 2 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 vWF_A PF12450.8 EPE33638.1 - 0.0049 16.8 0.2 0.18 11.8 0.0 2.4 2 0 0 2 2 2 1 von Willebrand factor Inhibitor_I36 PF03995.13 EPE33638.1 - 4.9 7.1 7.2 3.5 7.6 0.1 3.4 3 1 0 3 3 3 0 Peptidase inhibitor family I36 DIOX_N PF14226.6 EPE33641.1 - 1.8e-23 83.5 0.0 2.7e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPE33641.1 - 2.4e-12 47.2 0.0 4.6e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.8 EPE33642.1 - 1.2e-76 257.1 0.0 1.8e-76 256.6 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EPE33642.1 - 2.5e-27 95.1 0.0 5.1e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 EPE33642.1 - 0.001 19.5 0.0 0.0034 17.8 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain LprI PF07007.12 EPE33642.1 - 0.13 12.9 0.1 2.7 8.7 0.1 2.6 2 0 0 2 2 2 0 Lysozyme inhibitor LprI DUF3606 PF12244.8 EPE33642.1 - 0.34 10.9 2.5 31 4.6 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3606) TruB_N PF01509.18 EPE33643.1 - 2.4e-42 144.8 0.0 7.2e-42 143.3 0.0 1.7 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EPE33643.1 - 1.3e-08 34.8 0.0 5.5e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain Baculo_PP31 PF05311.11 EPE33643.1 - 0.024 14.2 0.0 0.078 12.5 0.0 1.8 2 1 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) LAL_C2 PF18603.1 EPE33643.1 - 0.047 13.8 0.2 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 zf-MYND PF01753.18 EPE33644.1 - 6.5e-07 29.3 18.8 1.9e-06 27.8 18.8 1.9 1 0 0 1 1 1 1 MYND finger SelP_N PF04592.14 EPE33644.1 - 5.2 6.4 13.7 2.8 7.3 6.4 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF629 PF04780.12 EPE33645.1 - 1.1 7.8 2.2 1.9 6.9 2.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF629) PRIMA1 PF16101.5 EPE33645.1 - 9.5 6.3 8.4 8.3 6.5 6.8 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 F-box PF00646.33 EPE33646.1 - 1.9e-05 24.4 2.5 1.9e-05 24.4 2.5 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EPE33646.1 - 3.2e-05 23.7 1.5 9.4e-05 22.2 1.5 1.8 1 0 0 1 1 1 1 F-box-like CcmD PF04995.14 EPE33647.1 - 0.00031 20.8 1.0 0.00046 20.2 1.0 1.3 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) ASFV_J13L PF05568.11 EPE33647.1 - 0.0096 15.7 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 African swine fever virus J13L protein FixQ PF05545.11 EPE33647.1 - 0.01 15.8 0.2 0.016 15.1 0.2 1.2 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF4448 PF14610.6 EPE33647.1 - 0.015 15.0 0.1 0.019 14.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Adeno_E3_CR2 PF02439.15 EPE33647.1 - 0.017 14.8 1.3 0.017 14.8 1.3 1.5 1 1 1 2 2 2 0 Adenovirus E3 region protein CR2 Aph-1 PF06105.12 EPE33647.1 - 0.035 13.5 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 Aph-1 protein Comm PF15957.5 EPE33647.1 - 0.041 14.2 0.0 0.05 13.9 0.0 1.1 1 0 0 1 1 1 0 Commissureless FeoB_associated PF12669.7 EPE33647.1 - 0.11 12.9 0.3 0.19 12.2 0.3 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF3377 PF11857.8 EPE33647.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TrbC PF04956.13 EPE33648.1 - 0.0079 16.4 7.3 0.034 14.3 0.3 3.3 3 0 0 3 3 3 1 TrbC/VIRB2 family MARVEL PF01284.23 EPE33648.1 - 0.62 10.1 19.1 0.028 14.4 3.7 3.1 1 1 2 3 3 3 0 Membrane-associating domain CBP_BcsF PF11120.8 EPE33648.1 - 3.9 7.7 5.8 45 4.3 0.1 3.3 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsF zf-C2H2_aberr PF17017.5 EPE33649.1 - 0.00021 21.5 3.9 0.00031 20.9 1.4 2.1 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2 PF00096.26 EPE33649.1 - 0.0004 20.7 16.7 0.018 15.5 2.6 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 EPE33649.1 - 0.024 14.9 4.9 0.078 13.3 4.6 2.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 EPE33649.1 - 0.029 15.2 18.4 0.056 14.3 2.2 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger DUF2964 PF11177.8 EPE33650.1 - 0.083 13.1 0.5 0.083 13.1 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) HET PF06985.11 EPE33651.1 - 8.3e-23 81.4 0.1 1.8e-22 80.3 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 EPE33651.1 - 0.0053 17.3 0.0 0.2 12.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Thioredoxin PF00085.20 EPE33652.1 - 6.6e-25 87.1 0.3 1.8e-24 85.7 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin PITH PF06201.13 EPE33652.1 - 1.9e-13 50.9 0.0 3.3e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 PITH domain OST3_OST6 PF04756.13 EPE33652.1 - 3.4e-06 26.6 0.0 4.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EPE33652.1 - 0.00014 22.3 0.2 0.00044 20.7 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EPE33652.1 - 0.00029 21.0 0.0 0.00063 19.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EPE33652.1 - 0.0033 17.3 0.1 0.0078 16.1 0.1 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EPE33652.1 - 0.0039 17.5 0.0 0.008 16.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EPE33652.1 - 0.035 13.8 0.1 0.075 12.7 0.1 1.6 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 EPE33652.1 - 0.036 13.8 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin TIM21 PF08294.11 EPE33654.1 - 1.1e-43 148.6 0.0 1.3e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 EPE33654.1 - 8.4e-05 22.3 0.0 0.00022 21.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 B12D PF06522.11 EPE33654.1 - 0.13 12.0 0.8 0.84 9.5 0.0 2.5 2 1 1 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit ArfGap PF01412.18 EPE33655.1 - 1.9e-35 121.5 0.1 3.8e-35 120.5 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Choline_transpo PF04515.12 EPE33656.1 - 1.1e-78 264.8 30.1 1.1e-78 264.8 30.1 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 EPE33656.1 - 0.086 13.5 4.5 0.19 12.4 4.5 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Thioredox_DsbH PF03190.15 EPE33657.1 - 0.087 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Imm61 PF15598.6 EPE33658.1 - 0.052 13.5 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 61 TFIID-18kDa PF02269.16 EPE33662.1 - 8e-29 99.5 2.6 2.4e-28 98.0 0.4 2.5 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 EPE33662.1 - 0.033 14.3 0.0 0.092 12.8 0.0 1.8 1 1 0 1 1 1 0 hTAFII28-like protein conserved region TPR_1 PF00515.28 EPE33663.1 - 2.9e-09 36.4 3.3 0.0053 16.5 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPE33663.1 - 2.4e-06 27.2 1.9 0.04 14.0 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPE33663.1 - 0.00038 20.4 1.6 0.011 15.8 0.3 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE33663.1 - 0.0011 19.1 3.1 0.0023 18.1 3.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EPE33663.1 - 0.013 16.0 0.5 0.042 14.4 0.4 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 EPE33663.1 - 0.11 12.9 0.4 1.8 9.1 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DNA_topoisoIV PF00521.20 EPE33665.1 - 9.9e-122 406.9 0.0 1.4e-121 406.3 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EPE33665.1 - 1.3e-49 167.7 0.8 3.8e-49 166.2 0.8 1.9 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EPE33665.1 - 1.9e-25 89.3 1.9 3.9e-25 88.3 1.9 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EPE33665.1 - 2.1e-13 50.7 0.0 7.1e-13 49.1 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EPE33665.1 - 1.2e-05 25.4 0.0 4.7e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 EPE33665.1 - 0.00019 21.3 0.2 0.00084 19.2 0.2 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Curto_V2 PF07325.11 EPE33665.1 - 0.05 13.5 0.1 0.25 11.2 0.1 2.2 1 0 0 1 1 1 0 Curtovirus V2 protein DUF3785 PF12653.7 EPE33665.1 - 0.19 11.9 7.0 0.41 10.8 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) NusA_N PF08529.11 EPE33665.1 - 0.22 11.9 2.8 1.1 9.7 0.0 2.9 2 0 0 2 2 2 0 NusA N-terminal domain RabGAP-TBC PF00566.18 EPE33666.1 - 2.8e-49 167.7 0.5 7.5e-49 166.3 0.0 2.0 3 0 0 3 3 3 1 Rab-GTPase-TBC domain NuiA PF07924.11 EPE33666.1 - 0.61 10.5 2.6 2.3 8.6 2.6 1.9 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein DUF4201 PF13870.6 EPE33666.1 - 4.7 6.9 24.7 0.079 12.7 8.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) NACHT_N PF17100.5 EPE33667.1 - 3.8e-25 89.1 1.7 7.4e-25 88.1 1.7 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 EPE33667.1 - 1.7e-08 34.9 0.1 3.6e-06 27.5 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) NACHT PF05729.12 EPE33667.1 - 1.7e-08 34.5 0.1 4.6e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 EPE33667.1 - 2.2e-08 34.2 0.0 0.0012 19.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPE33667.1 - 4.9e-06 27.0 0.2 0.2 12.3 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) AAA_22 PF13401.6 EPE33667.1 - 0.00018 21.8 0.0 0.00082 19.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ank_3 PF13606.6 EPE33667.1 - 0.00035 20.8 0.1 11 7.0 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat AAA_16 PF13191.6 EPE33667.1 - 0.0017 18.8 0.0 0.013 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Ank PF00023.30 EPE33667.1 - 0.069 13.6 0.1 29 5.3 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat AAA PF00004.29 EPE33667.1 - 0.072 13.5 0.0 0.22 12.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SET PF00856.28 EPE33668.1 - 2.3e-08 34.6 0.1 3.8e-07 30.7 0.2 2.6 2 1 0 2 2 2 1 SET domain APH PF01636.23 EPE33670.1 - 6.1e-09 36.2 0.0 1.3e-08 35.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE33670.1 - 0.00066 19.3 0.0 0.00096 18.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EPE33670.1 - 0.015 14.7 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase_Tyr PF07714.17 EPE33670.1 - 0.022 14.0 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.22 EPE33670.1 - 0.04 13.5 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family AOC_like PF18678.1 EPE33670.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain zf-CCHC_3 PF13917.6 EPE33670.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Zinc knuckle Abhydrolase_2 PF02230.16 EPE33671.1 - 4.9e-19 69.0 0.0 2.2e-08 34.2 0.0 2.4 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EPE33671.1 - 1.2e-06 28.2 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EPE33671.1 - 0.00039 19.7 0.0 0.0097 15.2 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 FSH1 PF03959.13 EPE33671.1 - 0.0029 17.3 0.0 0.0051 16.5 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 EPE33671.1 - 0.003 17.1 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EPE33671.1 - 0.039 13.8 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold dsrm PF00035.26 EPE33674.1 - 0.00015 22.4 0.0 0.00032 21.3 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 EPE33674.1 - 0.00023 21.3 0.0 0.0094 16.1 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EPE33674.1 - 0.077 13.6 0.0 0.22 12.2 0.0 1.8 2 1 0 2 2 2 0 Ribonuclease III domain DUF1616 PF07760.11 EPE33675.1 - 0.19 11.1 0.0 0.19 11.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) La PF05383.17 EPE33676.1 - 1.4e-16 60.3 0.0 2.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 La domain DUF1501 PF07394.12 EPE33678.1 - 0.87 8.6 5.2 1.6 7.7 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) CAP_N PF01213.19 EPE33679.1 - 1.2e-114 383.1 2.0 1.2e-114 383.1 2.0 1.8 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EPE33679.1 - 4.5e-59 198.6 4.8 6.1e-59 198.1 4.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EPE33679.1 - 0.0079 15.9 3.7 0.01 15.6 2.2 1.7 1 1 1 2 2 2 1 Tubulin binding cofactor C PfkB PF00294.24 EPE33680.1 - 4.8e-14 52.4 0.0 4.5e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase MCM PF00493.23 EPE33681.1 - 5.4e-98 326.6 0.3 1.1e-97 325.5 0.3 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EPE33681.1 - 3.7e-32 110.8 0.0 6.8e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EPE33681.1 - 7.5e-24 84.0 1.3 1.6e-23 82.9 1.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EPE33681.1 - 2.5e-13 50.5 0.2 6.7e-13 49.1 0.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EPE33681.1 - 8.8e-08 31.8 0.1 1.4e-06 27.8 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EPE33681.1 - 0.0041 17.0 0.0 0.0092 15.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EPE33681.1 - 0.012 15.3 0.0 0.041 13.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain NAM-associated PF14303.6 EPE33681.1 - 9.9 6.9 6.5 22 5.8 6.5 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF4680 PF15730.5 EPE33682.1 - 0.13 12.6 0.6 12 6.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) Carb_bind PF10645.9 EPE33683.1 - 1.1e-24 86.4 22.0 3.6e-15 55.9 10.0 3.4 3 1 1 4 4 4 2 Carbohydrate binding HABP4_PAI-RBP1 PF04774.15 EPE33683.1 - 1.5 9.7 6.6 2.7 8.8 6.6 1.4 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family LDB19 PF13002.7 EPE33685.1 - 5.6e-40 137.1 1.0 2e-39 135.3 0.9 1.9 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.29 EPE33685.1 - 4.7e-07 30.0 0.0 1.4e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.11 EPE33685.1 - 3e-05 23.7 0.0 4.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 SpoOM protein Rgp1 PF08737.10 EPE33685.1 - 0.12 11.5 0.1 0.26 10.4 0.0 1.5 2 0 0 2 2 2 0 Rgp1 SATase_N PF06426.14 EPE33687.1 - 0.037 14.4 0.0 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal 7tm_2 PF00002.24 EPE33687.1 - 0.076 12.3 3.2 0.088 12.1 2.1 1.6 2 0 0 2 2 2 0 7 transmembrane receptor (Secretin family) CoA_binding_3 PF13727.6 EPE33687.1 - 0.71 9.9 3.6 1.3 9.0 3.6 1.4 1 0 0 1 1 1 0 CoA-binding domain Aldedh PF00171.22 EPE33692.1 - 3.2e-162 540.2 0.4 3.8e-162 540.0 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short_C2 PF13561.6 EPE33693.1 - 5.5e-53 179.9 0.3 6.9e-53 179.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE33693.1 - 1.9e-45 154.7 0.9 2.6e-45 154.3 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE33693.1 - 4.4e-14 52.8 0.5 7.3e-14 52.1 0.5 1.3 1 0 0 1 1 1 1 KR domain FdsD PF11390.8 EPE33693.1 - 0.14 12.5 0.2 0.35 11.2 0.2 1.6 1 0 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD Fungal_trans PF04082.18 EPE33694.1 - 2.7e-18 65.9 0.1 8.9e-18 64.3 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE33694.1 - 7.3e-09 35.6 10.1 1.3e-08 34.8 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 EPE33695.1 - 1.3e-83 281.4 28.3 1.5e-83 281.2 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE33695.1 - 5.9e-13 48.5 63.9 1.7e-11 43.6 32.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_3 PF13738.6 EPE33696.1 - 1.2e-14 54.2 0.2 3.8e-13 49.4 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE33696.1 - 1.2e-11 44.7 0.0 4.4e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 EPE33696.1 - 4.1e-11 42.0 1.0 4.1e-10 38.7 0.4 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EPE33696.1 - 1.1e-07 31.3 0.2 0.00029 20.1 0.0 3.5 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EPE33696.1 - 1.4e-06 27.8 0.0 0.00016 21.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPE33696.1 - 0.00012 22.1 0.0 0.012 15.6 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 EPE33696.1 - 0.00013 21.7 0.0 0.033 13.8 0.0 2.7 2 2 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EPE33696.1 - 0.012 14.9 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family adh_short_C2 PF13561.6 EPE33697.1 - 2.7e-49 167.9 0.2 4.5e-49 167.1 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE33697.1 - 2.5e-37 128.2 1.4 4.4e-37 127.4 1.4 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE33697.1 - 7.6e-08 32.5 1.8 7.9e-08 32.4 0.2 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EPE33697.1 - 7e-05 22.1 0.0 9.5e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Transketolase_N PF00456.21 EPE33698.1 - 4.3e-111 371.1 0.1 6.9e-111 370.4 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EPE33698.1 - 1.6e-33 115.9 0.0 4.2e-33 114.5 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EPE33698.1 - 1e-13 51.2 0.0 2.7e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EPE33698.1 - 1.8e-06 27.4 0.4 1.1e-05 24.9 0.4 2.1 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EPE33698.1 - 0.0017 18.1 0.8 0.008 16.0 0.8 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF3343 PF11823.8 EPE33698.1 - 0.013 14.9 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) E1_dh PF00676.20 EPE33698.1 - 0.11 11.4 0.2 0.24 10.3 0.2 1.5 1 0 0 1 1 1 0 Dehydrogenase E1 component Epimerase PF01370.21 EPE33699.1 - 1.3e-11 44.4 0.0 2.3e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE33699.1 - 1e-07 31.3 0.0 1.5e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EPE33699.1 - 9.1e-07 28.9 0.0 1.3e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EPE33699.1 - 0.00029 20.1 0.0 0.00061 19.0 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 EPE33699.1 - 0.0011 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EPE33699.1 - 0.0012 18.3 0.1 0.11 11.9 0.0 2.5 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase LysR_substrate PF03466.20 EPE33699.1 - 0.0093 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 LysR substrate binding domain Cyclase PF04199.13 EPE33700.1 - 9.5e-17 61.5 0.0 1.7e-15 57.5 0.0 2.1 1 1 1 2 2 2 2 Putative cyclase p450 PF00067.22 EPE33701.1 - 3e-41 141.6 0.0 3.9e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Scytalone_dh PF02982.14 EPE33702.1 - 1.1e-65 220.2 0.6 1.4e-65 220.0 0.6 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 EPE33702.1 - 7e-05 23.0 0.2 8.9e-05 22.6 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain adh_short_C2 PF13561.6 EPE33703.1 - 6.7e-52 176.4 0.1 1.1e-51 175.6 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE33703.1 - 2.9e-49 167.2 0.3 3.7e-49 166.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE33703.1 - 2e-11 44.2 0.2 2.8e-11 43.7 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE33703.1 - 0.001 18.6 0.1 0.0029 17.1 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ketoacyl-synt PF00109.26 EPE33704.1 - 1.1e-81 274.1 0.0 2e-81 273.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EPE33704.1 - 3.9e-68 229.7 2.9 1.5e-64 218.0 0.0 3.3 2 1 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EPE33704.1 - 1.3e-50 172.7 0.0 7e-50 170.3 0.1 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE33704.1 - 2.1e-33 114.8 0.1 8.3e-33 112.9 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EPE33704.1 - 4.7e-25 89.1 0.0 3.7e-24 86.1 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 EPE33704.1 - 3.5e-21 75.7 0.0 1.2e-20 74.0 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase PP-binding PF00550.25 EPE33704.1 - 4.9e-11 42.8 1.1 6.1e-10 39.3 0.4 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 EPE33704.1 - 1.7e-06 28.8 0.5 2.7e-05 24.9 0.1 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 EPE33704.1 - 6e-05 22.5 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EPE33704.1 - 6.3e-05 23.4 0.0 0.00018 21.9 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension VirD1 PF07328.11 EPE33704.1 - 0.091 12.7 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 APH PF01636.23 EPE33705.1 - 3.7e-19 69.6 0.0 5.3e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE33705.1 - 4.1e-05 23.3 0.0 6.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EPE33705.1 - 0.00014 21.6 0.1 0.035 13.7 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Pkinase PF00069.25 EPE33705.1 - 0.00021 20.7 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Fructosamin_kin PF03881.14 EPE33705.1 - 0.0028 16.9 0.1 0.29 10.3 0.0 2.1 2 0 0 2 2 2 2 Fructosamine kinase Kdo PF06293.14 EPE33705.1 - 0.03 13.7 0.1 4.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EPE33705.1 - 0.057 12.7 0.0 0.22 10.8 0.0 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase DUF1679 PF07914.11 EPE33705.1 - 0.085 11.7 0.2 2 7.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1679) DUF932 PF06067.11 EPE33705.1 - 0.13 12.0 0.1 0.21 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) PLA2_B PF01735.18 EPE33705.1 - 0.13 10.6 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Lysophospholipase catalytic domain GIT1_C PF12205.8 EPE33707.1 - 0.08 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term TAF4 PF05236.14 EPE33708.1 - 4.9e-37 128.2 0.0 4.1e-36 125.2 0.0 2.1 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 EPE33709.1 - 2.6e-90 301.7 0.0 3.7e-90 301.2 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EPE33709.1 - 1.9e-29 102.2 0.0 4.9e-29 100.8 0.0 1.7 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.27 EPE33709.1 - 5.5e-19 68.9 0.9 9.6e-19 68.2 0.9 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EPE33709.1 - 3.8e-18 65.6 0.0 6.3e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EPE33709.1 - 3.4e-12 46.1 0.0 7.1e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EPE33709.1 - 1.6e-06 27.8 0.3 3.5e-06 26.7 0.3 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EPE33709.1 - 3.2e-06 27.1 0.1 7e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EPE33709.1 - 0.22 10.7 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-like family DnaJ PF00226.31 EPE33710.1 - 5.7e-16 58.4 1.9 9e-16 57.8 0.6 2.1 2 0 0 2 2 2 1 DnaJ domain DUF3740 PF12548.8 EPE33711.1 - 0.00076 19.9 0.4 0.0014 19.1 0.4 1.5 1 0 0 1 1 1 1 Sulfatase protein Mei4 PF13971.6 EPE33711.1 - 0.0073 15.8 5.7 0.017 14.6 5.7 1.8 1 1 0 1 1 1 1 Meiosis-specific protein Mei4 DivIC PF04977.15 EPE33711.1 - 0.21 11.4 2.7 19 5.1 1.8 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 EPE33711.1 - 0.75 9.1 5.4 1.2 8.3 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DIOX_N PF14226.6 EPE33712.1 - 2.3e-20 73.5 0.0 5.6e-20 72.3 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPE33712.1 - 3.6e-20 72.3 0.0 1.1e-19 70.8 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.14 EPE33713.1 - 3.1e-38 132.2 0.0 3.7e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 EPE33713.1 - 0.24 10.7 0.0 0.61 9.4 0.0 1.7 2 0 0 2 2 2 0 TatD related DNase CCDC144C PF14915.6 EPE33716.1 - 0.0092 15.1 0.2 0.01 14.9 0.2 1.1 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region Seryl_tRNA_N PF02403.22 EPE33717.1 - 0.0012 19.1 11.0 0.0016 18.7 11.0 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.19 EPE33717.1 - 0.0027 15.7 5.5 0.003 15.6 5.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF2439 PF10382.9 EPE33717.1 - 0.0045 17.3 1.1 0.006 16.9 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Tektin PF03148.14 EPE33717.1 - 0.012 14.4 4.9 0.015 14.1 4.9 1.1 1 0 0 1 1 1 0 Tektin family FapA PF03961.13 EPE33717.1 - 0.012 14.2 5.8 0.014 14.0 5.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A HIP1_clath_bdg PF16515.5 EPE33717.1 - 0.015 15.9 9.9 0.038 14.6 4.3 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF677 PF05055.12 EPE33717.1 - 0.023 13.6 4.8 0.026 13.4 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF677) HalX PF08663.10 EPE33717.1 - 0.031 14.6 6.3 0.7 10.2 0.4 2.1 2 0 0 2 2 2 0 HalX domain Spc7 PF08317.11 EPE33717.1 - 0.053 12.4 8.3 0.066 12.1 8.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein LPP PF04728.13 EPE33717.1 - 0.055 13.9 0.8 3.6 8.0 0.1 2.2 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DivIC PF04977.15 EPE33717.1 - 0.061 13.1 9.8 0.22 11.3 0.6 2.1 1 1 1 2 2 2 0 Septum formation initiator HALZ PF02183.18 EPE33717.1 - 0.076 13.2 6.2 1 9.7 0.3 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF3854 PF12965.7 EPE33717.1 - 0.077 13.0 1.1 0.096 12.7 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) DUF1690 PF07956.11 EPE33717.1 - 0.078 13.4 6.7 0.1 13.0 6.7 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Vps54_N PF10475.9 EPE33717.1 - 0.1 11.9 3.3 0.12 11.6 3.3 1.0 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Jnk-SapK_ap_N PF09744.9 EPE33717.1 - 0.12 12.6 9.9 0.16 12.2 9.9 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FAM184 PF15665.5 EPE33717.1 - 0.14 12.0 12.7 0.055 13.2 4.0 2.0 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Fib_alpha PF08702.10 EPE33717.1 - 0.15 12.2 4.6 0.36 11.0 4.6 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 EPE33717.1 - 0.2 12.2 1.6 3.2 8.3 1.6 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein COG5 PF10392.9 EPE33717.1 - 0.21 11.8 2.6 0.28 11.4 2.6 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Fungal_TACC PF12709.7 EPE33717.1 - 0.23 11.9 11.1 0.35 11.4 2.8 2.1 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4200 PF13863.6 EPE33717.1 - 0.23 11.9 15.9 2.9 8.3 16.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) TolA_bind_tri PF16331.5 EPE33717.1 - 0.25 11.4 5.2 0.58 10.3 0.7 2.1 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF241 PF03087.14 EPE33717.1 - 0.27 11.0 6.2 0.32 10.8 6.2 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Zw10 PF06248.13 EPE33717.1 - 0.29 9.6 3.6 0.33 9.5 3.6 1.0 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 SlyX PF04102.12 EPE33717.1 - 0.3 11.7 4.5 0.77 10.4 0.5 2.1 1 1 1 2 2 2 0 SlyX BLOC1_2 PF10046.9 EPE33717.1 - 0.37 11.1 6.3 1.7 9.0 5.7 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 EPE33717.1 - 0.39 11.1 8.3 0.85 10.1 2.3 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF1003 PF06210.11 EPE33717.1 - 0.41 10.8 5.9 1 9.5 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) Atg14 PF10186.9 EPE33717.1 - 0.47 9.5 7.2 0.54 9.3 7.2 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FemAB PF02388.16 EPE33717.1 - 0.49 9.2 3.5 0.63 8.9 3.5 1.1 1 0 0 1 1 1 0 FemAB family ZapB PF06005.12 EPE33717.1 - 0.58 10.6 12.4 0.61 10.6 2.7 2.2 1 1 1 2 2 2 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 EPE33717.1 - 0.68 10.2 14.6 0.16 12.3 5.8 2.1 1 1 1 2 2 2 0 ABC transporter C-terminal domain LapA_dom PF06305.11 EPE33717.1 - 0.83 9.5 3.5 1.2 9.0 0.2 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4140 PF13600.6 EPE33717.1 - 0.88 10.1 8.9 1.6 9.2 1.5 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF724 PF05266.14 EPE33717.1 - 0.89 9.4 9.7 1.1 9.1 8.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 EPE33717.1 - 1 9.4 4.5 1.4 9.0 4.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Swi5 PF07061.11 EPE33717.1 - 1.3 9.2 8.4 2.5 8.2 1.1 2.1 1 1 1 2 2 2 0 Swi5 Cauli_AT PF03233.13 EPE33717.1 - 1.6 8.6 7.2 2 8.3 7.2 1.1 1 0 0 1 1 1 0 Aphid transmission protein Pox_A_type_inc PF04508.12 EPE33717.1 - 1.8 8.5 8.7 6.8 6.7 2.8 2.9 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat Cep57_CLD_2 PF14197.6 EPE33717.1 - 2 8.6 12.2 1.6 8.9 1.5 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 UPF0242 PF06785.11 EPE33717.1 - 2.3 8.3 10.3 2.9 7.9 10.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 EPE33717.1 - 2.4 7.3 3.6 2.8 7.1 3.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1192 PF06698.11 EPE33717.1 - 2.5 8.2 11.7 0.63 10.1 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) DUF641 PF04859.12 EPE33717.1 - 2.7 8.3 8.3 7.9 6.8 8.3 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) APG6_N PF17675.1 EPE33717.1 - 2.8 8.5 13.0 2.6 8.6 11.7 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF465 PF04325.13 EPE33717.1 - 3.7 7.7 16.1 0.38 10.8 0.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF465) TSC22 PF01166.18 EPE33717.1 - 4.4 7.7 9.3 0.42 11.0 2.2 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family BST2 PF16716.5 EPE33717.1 - 4.5 7.9 11.5 1 10.0 2.8 2.0 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 FAM76 PF16046.5 EPE33717.1 - 4.7 6.5 8.0 5.6 6.2 8.0 1.1 1 0 0 1 1 1 0 FAM76 protein bZIP_1 PF00170.21 EPE33717.1 - 5.1 7.3 13.7 1.2 9.2 1.0 2.4 1 1 0 2 2 2 0 bZIP transcription factor DUF2098 PF09871.9 EPE33718.1 - 6.5 7.2 12.0 1.2 9.5 7.6 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) DUF373 PF04123.13 EPE33719.1 - 0.64 9.4 14.0 0.8 9.1 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF1308 PF07000.11 EPE33720.1 - 7.6e-12 45.5 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 EPE33720.1 - 0.013 14.8 5.1 1.3 8.3 5.1 3.0 1 1 0 1 1 1 0 Family of unknown function (DUF5614) Cwf_Cwc_15 PF04889.12 EPE33720.1 - 0.97 9.1 5.7 1.7 8.3 5.3 1.6 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 EPE33721.1 - 8.4e-16 58.1 4.2 1.8e-06 28.5 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE33721.1 - 4.9e-05 23.6 0.0 1.2 9.4 0.0 4.5 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE33721.1 - 0.016 15.1 0.0 11 5.8 0.0 4.0 3 2 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Mito_carr PF00153.27 EPE33722.1 - 2.3e-55 184.5 3.2 6.7e-19 67.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CTU2 PF10288.9 EPE33723.1 - 1.1e-12 48.1 6.0 1.1e-11 44.9 0.4 3.2 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 DZR PF12773.7 EPE33723.1 - 0.0018 18.2 5.2 0.02 14.9 1.6 2.3 2 0 0 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.6 EPE33723.1 - 0.56 10.0 0.1 0.56 10.0 0.1 2.5 3 0 0 3 3 3 0 zinc-ribbon domain ZZ PF00569.17 EPE33723.1 - 6.7 6.6 7.4 20 5.1 3.7 2.7 2 1 1 3 3 3 0 Zinc finger, ZZ type Lung_7-TM_R PF06814.13 EPE33724.1 - 2.9e-73 246.7 11.9 3.5e-73 246.4 11.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GCV_T PF01571.21 EPE33725.1 - 1.3e-08 34.5 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Nramp PF01566.18 EPE33726.1 - 1.6e-87 293.8 19.9 1.6e-87 293.8 19.9 2.1 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein DCP2 PF05026.13 EPE33727.1 - 2.2e-31 108.0 1.2 4.3e-31 107.1 1.2 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EPE33727.1 - 1.9e-16 60.3 0.0 3.3e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.6 EPE33728.1 - 7.6e-34 116.1 0.3 1e-33 115.7 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Ribonuc_red_sm PF00268.21 EPE33729.1 - 9.9e-123 409.0 4.2 1.2e-122 408.7 4.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.12 EPE33730.1 - 1.8e-34 118.0 1.7 2.3e-34 117.7 1.7 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) MGC-24 PF05283.11 EPE33730.1 - 0.044 14.2 1.0 0.058 13.8 1.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin F-box-like_2 PF13013.6 EPE33731.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain Mucin PF01456.17 EPE33732.1 - 0.087 12.8 26.8 0.031 14.2 16.0 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein GFO_IDH_MocA PF01408.22 EPE33734.1 - 1.3e-14 55.1 0.0 2.3e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold RhoGAP PF00620.27 EPE33735.1 - 7.9e-35 119.9 0.0 2.7e-34 118.2 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EPE33735.1 - 1.3e-33 115.0 36.5 1.9e-12 47.2 6.5 5.2 5 0 0 5 5 5 4 LIM domain Het-C PF07217.11 EPE33736.1 - 3.8e-281 933.6 0.0 4.6e-281 933.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Comm PF15957.5 EPE33738.1 - 0.071 13.5 1.3 2.2 8.6 0.1 2.4 2 0 0 2 2 2 0 Commissureless Pkinase PF00069.25 EPE33739.1 - 7.9e-61 205.7 0.0 4.7e-40 137.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE33739.1 - 7e-26 91.1 0.0 4.4e-20 72.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EPE33739.1 - 2.3e-14 53.5 0.0 4.6e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EPE33739.1 - 1.5e-07 31.1 0.0 2.4e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EPE33739.1 - 0.00012 22.1 0.0 0.005 16.8 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family PAS_9 PF13426.7 EPE33739.1 - 0.0045 17.2 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 PAS domain Haspin_kinase PF12330.8 EPE33739.1 - 0.0062 15.5 0.1 0.012 14.6 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EPE33739.1 - 0.015 14.9 0.0 2.2 7.9 0.0 2.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EPE33739.1 - 0.02 14.2 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EPE33739.1 - 0.085 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 GET2 PF08690.10 EPE33739.1 - 1.6 8.3 3.7 5.4 6.6 3.7 1.9 1 0 0 1 1 1 0 GET complex subunit GET2 DnaJ PF00226.31 EPE33741.1 - 4.4e-18 65.2 1.1 4.4e-18 65.2 1.1 2.1 2 0 0 2 2 2 1 DnaJ domain Nup188 PF10487.9 EPE33741.1 - 0.031 12.2 0.9 0.041 11.8 0.9 1.0 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 DUF5454 PF17535.2 EPE33741.1 - 0.061 12.7 0.2 0.092 12.1 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5454) Octopine_DH PF02317.17 EPE33741.1 - 0.14 12.3 0.2 0.51 10.4 0.0 1.8 2 0 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain T3SSipB PF16535.5 EPE33741.1 - 0.2 12.1 1.2 0.37 11.3 1.2 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB MFS_1 PF07690.16 EPE33742.1 - 2.9e-36 125.1 62.7 3.8e-36 124.8 58.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EPE33742.1 - 0.0021 17.0 15.8 0.0021 17.0 15.8 2.3 2 0 0 2 2 2 2 MFS_1 like family RTA1 PF04479.13 EPE33743.1 - 9.1e-66 221.4 11.0 9.1e-66 221.4 11.0 1.7 2 0 0 2 2 2 1 RTA1 like protein Poxvirus_B22R_C PF13168.6 EPE33743.1 - 0.046 13.2 0.1 0.67 9.4 0.0 2.1 2 0 0 2 2 2 0 Poxvirus B22R protein C-terminal MFS_1 PF07690.16 EPE33744.1 - 1.5e-47 162.2 47.8 1.5e-47 162.2 47.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE33744.1 - 2.2e-21 75.9 8.9 2.2e-21 75.9 8.9 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPE33744.1 - 7.6e-16 58.0 5.5 7.6e-16 58.0 5.5 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter ADH_zinc_N PF00107.26 EPE33745.1 - 1.9e-09 37.6 0.0 3.6e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE33745.1 - 0.0014 18.5 0.1 0.0037 17.1 0.1 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.18 EPE33746.1 - 2.6e-07 30.7 4.5 4.5e-07 29.9 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 EPE33747.1 - 1.8e-75 253.8 0.0 4.2e-75 252.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 EPE33747.1 - 5.5e-72 242.7 0.1 8.3e-72 242.1 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EPE33747.1 - 6.3e-71 239.4 2.2 9.3e-71 238.9 2.2 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 EPE33747.1 - 3e-52 177.1 0.1 3.1e-51 173.8 0.0 2.6 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EPE33747.1 - 4.5e-48 164.0 0.0 1e-47 162.8 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EPE33747.1 - 2e-45 155.7 1.1 4e-45 154.7 1.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE33747.1 - 3.5e-31 107.7 0.1 2e-30 105.2 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EPE33747.1 - 1.7e-30 106.0 0.0 1e-27 96.9 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 EPE33747.1 - 2.5e-19 69.8 0.0 1.3e-18 67.5 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EPE33747.1 - 9.8e-18 64.3 2.2 8.6e-10 38.8 0.1 3.2 3 0 0 3 3 2 2 Phosphopantetheine attachment site Epimerase PF01370.21 EPE33747.1 - 2e-17 63.5 0.0 5.7e-13 48.9 0.0 3.3 4 0 0 4 4 4 2 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 EPE33747.1 - 1.1e-13 51.7 0.0 3.3e-13 50.1 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 EPE33747.1 - 1.2e-12 48.4 0.0 6.3e-12 46.0 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE33747.1 - 2.1e-12 47.2 0.0 5.5e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE33747.1 - 4.4e-11 43.3 0.0 1.8e-10 41.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE33747.1 - 1.1e-08 35.1 0.0 3.5e-08 33.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain adh_short PF00106.25 EPE33747.1 - 1.4e-08 34.5 0.0 7.9e-08 32.0 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.19 EPE33747.1 - 2.2e-07 30.2 0.0 0.00017 20.7 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.18 EPE33747.1 - 1.5e-06 27.8 0.0 3.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GDP_Man_Dehyd PF16363.5 EPE33747.1 - 1.5e-06 27.8 0.0 0.045 13.1 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 EPE33747.1 - 2e-05 24.1 0.0 5.9e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 EPE33747.1 - 0.00025 20.7 0.0 0.0007 19.2 0.0 1.8 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 EPE33747.1 - 0.0014 17.8 0.0 0.036 13.2 0.0 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain DREV PF05219.12 EPE33747.1 - 0.034 13.2 0.0 0.072 12.2 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase adh_short PF00106.25 EPE33749.1 - 1.5e-24 86.6 0.3 1.9e-24 86.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE33749.1 - 1.5e-20 73.7 0.2 2.6e-20 73.0 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE33749.1 - 6.5e-14 52.2 0.1 9.5e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE33749.1 - 1.1e-08 34.6 0.1 1.4e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pyr_redox_2 PF07992.14 EPE33749.1 - 0.02 14.1 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AFOR_N PF02730.15 EPE33749.1 - 0.088 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain Zn_clus PF00172.18 EPE33750.1 - 0.028 14.5 1.1 0.091 12.9 1.1 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 EPE33752.1 - 6.8e-61 206.2 0.0 9.8e-61 205.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE33752.1 - 4.4e-30 105.1 0.0 7.7e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EPE33752.1 - 0.0012 18.0 0.1 0.0017 17.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EPE33752.1 - 0.01 15.1 0.1 0.025 13.8 0.1 1.5 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EPE33752.1 - 0.031 13.4 0.1 6.3 5.8 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 EPE33752.1 - 0.047 12.9 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EPE33752.1 - 0.17 10.7 0.1 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase JmjC PF02373.22 EPE33753.1 - 1.7e-39 134.8 0.2 1.7e-39 134.8 0.2 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 EPE33753.1 - 1.9e-18 66.6 4.2 4.8e-18 65.3 4.2 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EPE33753.1 - 2.1e-17 63.2 7.6 4.6e-17 62.1 7.6 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.17 EPE33753.1 - 4.5e-12 45.7 0.5 1.2e-11 44.4 0.5 1.8 1 0 0 1 1 1 1 jmjN domain Rhomboid PF01694.22 EPE33756.1 - 7.6e-25 87.7 5.4 1.3e-24 86.9 5.4 1.4 1 0 0 1 1 1 1 Rhomboid family PVL_ORF50 PF07768.11 EPE33757.1 - 0.066 13.5 0.1 0.066 13.5 0.1 2.4 3 0 0 3 3 3 0 PVL ORF-50-like family Paramyxo_C PF01692.18 EPE33757.1 - 7.2 5.9 8.3 15 4.9 8.3 1.5 1 0 0 1 1 1 0 Paramyxovirus non-structural protein C IU_nuc_hydro PF01156.19 EPE33760.1 - 1.9e-59 201.8 0.0 3.2e-59 201.0 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase LSM PF01423.22 EPE33761.1 - 5.1e-06 26.1 0.0 0.00031 20.4 0.0 2.2 1 1 1 2 2 2 2 LSM domain MCM PF00493.23 EPE33762.1 - 1.8e-104 347.8 0.1 3.7e-104 346.7 0.1 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EPE33762.1 - 1.8e-35 121.5 0.2 3.4e-35 120.6 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EPE33762.1 - 3.8e-28 97.7 1.5 9.8e-28 96.4 1.5 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EPE33762.1 - 1.5e-16 60.8 0.2 3.8e-16 59.6 0.2 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EPE33762.1 - 4.2e-06 26.3 0.0 0.00068 19.1 0.0 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EPE33762.1 - 4.1e-05 23.6 0.0 0.00012 22.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EPE33762.1 - 0.00032 20.6 0.1 0.0017 18.2 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EPE33762.1 - 0.044 13.5 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 EPE33762.1 - 0.13 12.7 0.4 0.65 10.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 EPE33763.1 - 5.9e-71 238.9 0.0 9.9e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE33763.1 - 1.3e-35 123.0 0.0 4.2e-35 121.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EPE33763.1 - 0.0026 17.1 0.2 0.0061 15.9 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPE33763.1 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPE33763.1 - 0.023 14.6 3.7 0.05 13.5 0.1 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EPE33763.1 - 0.11 11.4 0.0 0.11 11.4 0.0 2.1 3 0 0 3 3 3 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EPE33763.1 - 0.3 9.8 0.0 0.3 9.8 0.0 3.4 3 1 0 3 3 3 0 Fungal protein kinase Sulfotransfer_4 PF17784.1 EPE33764.1 - 7.7e-65 218.7 0.0 9e-65 218.5 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EPE33764.1 - 0.0011 19.4 0.1 0.015 15.7 0.1 2.4 1 1 0 1 1 1 1 Sulfotransferase family Carboxyl_trans PF01039.22 EPE33765.1 - 1.5e-77 261.4 0.0 2.3e-77 260.8 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EPE33766.1 - 4.2e-54 183.2 0.0 5.6e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EPE33766.1 - 4.5e-25 88.3 0.0 1.1e-24 87.1 0.0 1.7 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EPE33766.1 - 1.9e-10 40.8 0.0 3.7e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EPE33766.1 - 1.5e-08 34.4 0.0 2.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EPE33766.1 - 1.3e-05 25.4 0.0 2.5e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 EPE33766.1 - 0.00017 21.2 0.0 0.00026 20.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EPE33766.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 EPE33766.1 - 0.017 14.9 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 EPE33766.1 - 0.048 13.4 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon zf-RanBP PF00641.18 EPE33767.1 - 7.3e-20 70.0 8.9 5.3e-11 41.6 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 EPE33767.1 - 1.9e-07 30.8 0.0 4.6e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 EPE33767.1 - 0.0002 21.9 0.0 0.00029 21.4 0.0 1.2 1 0 0 1 1 1 1 Exonuclease IL1_propep PF02394.16 EPE33768.1 - 0.43 11.5 2.7 3.7 8.5 0.8 2.8 2 0 0 2 2 2 0 Interleukin-1 propeptide CAF1C_H4-bd PF12265.8 EPE33769.1 - 9e-28 96.3 0.2 7.4e-27 93.4 0.2 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EPE33769.1 - 2.7e-27 94.5 1.5 0.00017 22.3 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE33769.1 - 4e-05 23.8 0.6 1.5 9.2 0.0 4.9 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Leader_Erm PF08253.11 EPE33769.1 - 0.24 11.7 1.0 12 6.5 1.0 2.7 2 0 0 2 2 2 0 Erm Leader peptide XRN_M PF17846.1 EPE33770.1 - 9.2e-101 337.9 6.2 1.5e-100 337.2 6.2 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 EPE33770.1 - 9.2e-96 319.9 0.0 1.6e-95 319.1 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 EPE33770.1 - 4.8e-76 254.8 0.0 1e-75 253.7 0.0 1.6 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 EPE33770.1 - 4.2e-35 119.8 0.0 1.6e-34 117.9 0.0 2.1 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EPE33770.1 - 2.9e-23 81.7 0.3 7.1e-23 80.5 0.3 1.7 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 EPE33770.1 - 3.7e-07 30.1 0.4 1e-06 28.7 0.4 1.8 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 R3H PF01424.22 EPE33770.1 - 0.0024 17.8 0.0 0.0056 16.6 0.0 1.6 1 0 0 1 1 1 1 R3H domain Pmp3 PF01679.17 EPE33771.1 - 1.6e-22 79.4 7.8 2e-22 79.1 7.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF929 PF06053.11 EPE33771.1 - 0.097 12.0 0.3 0.2 10.9 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF929) SPC22 PF04573.12 EPE33772.1 - 1.4e-38 132.1 1.9 1.9e-37 128.4 1.9 2.0 1 1 0 1 1 1 1 Signal peptidase subunit Amino_oxidase PF01593.24 EPE33774.1 - 1.9e-39 136.2 0.0 3.4e-39 135.4 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPE33774.1 - 1.4e-05 25.2 0.0 4.4e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EPE33774.1 - 0.0044 16.3 0.1 0.0082 15.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE33774.1 - 0.054 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase BTB PF00651.31 EPE33775.1 - 1.2e-12 48.1 0.0 3e-12 46.8 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain TFIIA PF03153.13 EPE33775.1 - 8.6 6.2 16.1 12 5.7 16.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BTB PF00651.31 EPE33776.1 - 3e-09 37.1 0.1 7.6e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.31 EPE33777.1 - 6.6e-10 39.2 0.2 1.6e-09 37.9 0.2 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EPE33778.1 - 1.7e-10 41.1 0.1 3.1e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain SnoaL_2 PF12680.7 EPE33779.1 - 3.2e-07 30.9 0.4 5.9e-07 30.1 0.4 1.5 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EPE33779.1 - 0.00024 20.9 0.1 0.00058 19.7 0.1 1.7 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Vps62 PF06101.11 EPE33780.1 - 7.7e-51 173.0 0.1 9.9e-51 172.6 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 HET PF06985.11 EPE33781.1 - 1.7e-37 129.0 1.0 2.1e-37 128.7 1.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 EPE33783.1 - 2.6e-69 233.5 0.0 3.8e-69 233.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE33783.1 - 7.9e-47 159.7 0.0 1.6e-46 158.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPE33783.1 - 5.1e-06 25.5 0.1 2.1e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EPE33783.1 - 0.00015 21.2 0.0 0.00093 18.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Transglut_core PF01841.19 EPE33784.1 - 1.8e-10 41.2 0.1 7.5e-10 39.3 0.1 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily SH3_2 PF07653.17 EPE33784.1 - 5.4e-09 35.6 0.0 1.5e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EPE33784.1 - 7.8e-08 31.8 0.0 2e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPE33784.1 - 0.0025 17.6 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain HflK_N PF12221.8 EPE33784.1 - 0.079 13.0 0.2 0.29 11.2 0.2 1.9 1 0 0 1 1 1 0 Bacterial membrane protein N terminal DUF3431 PF11913.8 EPE33785.1 - 0.029 14.1 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3431) p53-inducible11 PF14936.6 EPE33785.1 - 0.087 12.9 0.7 0.19 11.7 0.7 1.5 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 KH_7 PF17214.3 EPE33785.1 - 0.2 11.7 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 KH domain MFS_1 PF07690.16 EPE33786.1 - 3.2e-43 148.0 47.0 3.2e-43 148.0 47.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE33786.1 - 6.8e-20 71.0 14.1 1.1e-19 70.4 14.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPE33786.1 - 1.4e-13 50.6 8.0 1.4e-13 50.6 8.0 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3522 PF12036.8 EPE33786.1 - 0.39 11.0 9.9 0.03 14.6 1.9 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF3522) DUF4083 PF13314.6 EPE33786.1 - 1 9.3 0.0 1 9.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) TMEM208_SND2 PF05620.11 EPE33786.1 - 7.9 6.2 9.3 12 5.6 0.1 3.7 3 2 1 4 4 4 0 SRP-independent targeting protein 2/TMEM208 p450 PF00067.22 EPE33787.1 - 1.6e-29 103.0 0.0 2.8e-29 102.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EPE33789.1 - 2.1e-29 102.6 0.0 2.6e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 EPE33791.1 - 1.3e-18 67.0 1.0 4.8e-18 65.2 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EPE33791.1 - 0.073 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like ARGLU PF15346.6 EPE33792.1 - 0.086 12.7 49.9 0.9 9.4 22.2 3.0 1 1 1 2 2 2 0 Arginine and glutamate-rich 1 DUF812 PF05667.11 EPE33792.1 - 0.62 8.9 27.9 0.93 8.3 24.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) pP_pnuc_2 PF18166.1 EPE33792.1 - 4.1 7.5 7.7 4.7 7.3 0.3 3.1 2 1 0 3 3 3 0 Predicted pPIWI-associating nuclease GerPC PF10737.9 EPE33792.1 - 5.3 7.1 14.7 9.1 6.3 13.6 1.7 1 1 1 2 2 2 0 Spore germination protein GerPC Fungal_trans_2 PF11951.8 EPE33793.1 - 3.4e-33 115.0 1.5 5.2e-33 114.4 1.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE33793.1 - 7.3e-07 29.2 6.5 1.3e-06 28.5 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ammonium_transp PF00909.21 EPE33794.1 - 4.6e-72 242.9 21.9 5.5e-72 242.6 21.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family AA_permease_2 PF13520.6 EPE33795.1 - 8.5e-44 150.0 54.4 1.1e-43 149.6 54.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE33795.1 - 7.8e-23 80.8 48.4 1.1e-22 80.3 48.4 1.0 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.18 EPE33796.1 - 8.8e-07 29.0 9.8 1.7e-06 28.0 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1100 PF06500.11 EPE33797.1 - 2e-09 36.7 0.0 3.2e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 EPE33797.1 - 2.9e-07 31.3 0.1 5.6e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE33797.1 - 0.063 12.9 0.0 2.8 7.5 0.1 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPE33797.1 - 0.085 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family ADH_zinc_N PF00107.26 EPE33798.1 - 3.1e-11 43.4 0.0 6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE33798.1 - 0.0012 19.8 0.0 0.0022 19.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE33798.1 - 0.0017 18.2 0.1 0.038 13.9 0.1 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 EPE33799.1 - 1.9e-43 148.8 46.2 1.9e-43 148.8 46.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE33799.1 - 1.3e-15 57.3 12.2 1.3e-15 57.3 12.2 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EPE33799.1 - 1.2e-14 53.7 21.9 7.4e-14 51.1 21.9 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EthD PF07110.11 EPE33801.1 - 2.9e-09 38.0 0.1 4.2e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EPE33801.1 - 0.00095 19.6 0.1 0.0014 19.1 0.1 1.2 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase DUF4188 PF13826.6 EPE33801.1 - 0.031 14.6 0.0 0.051 13.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4188) Ribul_P_3_epim PF00834.19 EPE33801.1 - 0.092 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family GlcNAc-1_reg PF18440.1 EPE33801.1 - 0.18 12.1 0.0 0.39 11.0 0.0 1.6 1 1 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain ketoacyl-synt PF00109.26 EPE33802.1 - 6.7e-71 238.8 0.0 1.2e-70 237.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 EPE33802.1 - 1.6e-70 237.8 0.0 6.6e-70 235.8 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 EPE33802.1 - 3.4e-62 210.6 0.0 5.1e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 EPE33802.1 - 1.4e-57 194.5 0.0 3.8e-55 186.6 0.0 2.6 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EPE33802.1 - 2.4e-48 164.9 0.0 3.6e-48 164.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.12 EPE33802.1 - 1.1e-42 146.0 0.0 5.4e-42 143.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EPE33802.1 - 1.9e-38 132.8 0.0 3.6e-38 131.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE33802.1 - 1.2e-31 109.2 0.0 3.5e-31 107.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.21 EPE33802.1 - 8.3e-22 77.8 0.0 1.9e-17 63.6 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EPE33802.1 - 5.7e-17 61.8 0.0 1e-12 47.9 0.0 2.7 2 0 0 2 2 2 2 short chain dehydrogenase Methyltransf_12 PF08242.12 EPE33802.1 - 1e-16 61.5 0.0 2.8e-16 60.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EPE33802.1 - 3.3e-16 59.4 4.0 4.8e-09 36.5 0.0 3.6 4 0 0 4 4 3 2 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 EPE33802.1 - 6.9e-13 49.1 0.0 3e-12 47.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE33802.1 - 6.9e-13 48.8 0.0 1.7e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE33802.1 - 9.5e-12 45.0 0.0 2.9e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 EPE33802.1 - 6.1e-11 41.9 0.0 8.8e-09 34.8 0.0 2.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_11 PF08241.12 EPE33802.1 - 1.1e-10 42.0 0.0 3.4e-10 40.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EPE33802.1 - 1.6e-09 38.2 0.0 7.5e-09 36.0 0.0 2.2 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short_C2 PF13561.6 EPE33802.1 - 1e-08 35.1 0.0 3.1e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase GDP_Man_Dehyd PF16363.5 EPE33802.1 - 8.4e-08 32.0 0.0 0.0069 15.8 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Ubie_methyltran PF01209.18 EPE33802.1 - 1.4e-05 24.6 0.0 3.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EPE33802.1 - 3.1e-05 23.8 0.0 7.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase NAD_binding_10 PF13460.6 EPE33802.1 - 0.00017 21.5 0.0 0.00098 19.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Thiolase_N PF00108.23 EPE33802.1 - 0.00087 18.7 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_33 PF10017.9 EPE33802.1 - 0.049 12.8 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent NmrA PF05368.13 EPE33802.1 - 0.053 13.1 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family Methyltransf_28 PF02636.17 EPE33802.1 - 0.08 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 EPE33802.1 - 0.091 12.4 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 Nodulation protein S (NodS) ABC_tran_CTD PF16326.5 EPE33803.1 - 0.015 15.6 1.4 0.17 12.1 0.1 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.15 EPE33803.1 - 0.054 13.3 1.4 0.12 12.1 0.0 2.1 2 1 0 2 2 2 0 Septum formation initiator PH PF00169.29 EPE33804.1 - 2.5e-06 27.9 0.7 5.5e-06 26.8 0.7 1.5 1 0 0 1 1 1 1 PH domain DUF2828 PF11443.8 EPE33804.1 - 1.4 6.9 8.0 2.3 6.2 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Atg14 PF10186.9 EPE33804.1 - 2.1 7.4 6.8 3.6 6.6 6.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RmlD_sub_bind PF04321.17 EPE33805.1 - 8.3e-54 182.6 0.0 1e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EPE33805.1 - 1.3e-21 77.2 0.0 1.6e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE33805.1 - 8.3e-10 38.1 0.0 1.8e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EPE33805.1 - 3.3e-09 36.3 0.1 4.3e-06 26.1 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EPE33805.1 - 7.4e-08 32.2 0.0 4.4e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EPE33805.1 - 1.6e-06 27.5 0.7 0.00031 20.0 0.1 2.9 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EPE33805.1 - 0.007 16.0 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EPE33805.1 - 0.032 14.1 0.1 0.098 12.5 0.1 1.6 1 1 0 1 1 1 0 NAD(P)H-binding KIND PF16474.5 EPE33806.1 - 0.56 10.1 3.6 5.3 6.9 0.2 2.3 2 0 0 2 2 2 0 Kinase non-catalytic C-lobe domain FliJ PF02050.16 EPE33807.1 - 0.0057 16.9 1.3 0.0057 16.9 1.3 1.5 2 0 0 2 2 2 1 Flagellar FliJ protein Peptidase_S41_N PF11918.8 EPE33807.1 - 0.014 15.6 0.7 0.028 14.7 0.6 1.7 1 1 0 1 1 1 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Spc7 PF08317.11 EPE33807.1 - 0.054 12.4 6.0 0.064 12.1 6.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein COMP PF11598.8 EPE33807.1 - 0.065 13.7 0.6 0.065 13.7 0.6 2.4 2 1 1 3 3 3 0 Cartilage oligomeric matrix protein YscO PF07321.12 EPE33807.1 - 0.15 12.0 9.6 0.1 12.6 1.2 2.3 2 1 0 2 2 2 0 Type III secretion protein YscO Occludin_ELL PF07303.13 EPE33807.1 - 0.16 12.8 4.5 2.4 8.9 1.2 2.3 1 1 0 2 2 2 0 Occludin homology domain DUF61 PF01886.16 EPE33807.1 - 0.21 11.6 1.5 0.41 10.7 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF61 DHR10 PF18595.1 EPE33807.1 - 0.7 10.0 9.5 0.35 10.9 0.8 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF1664 PF07889.12 EPE33807.1 - 0.95 9.5 3.2 4.6 7.3 3.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 EPE33807.1 - 1.7 9.1 4.1 23 5.5 0.2 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Hrs_helical PF12210.8 EPE33807.1 - 1.8 9.1 7.7 0.96 10.0 3.1 2.4 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate IPP-2 PF04979.14 EPE33809.1 - 1.1e-24 87.7 12.3 1.1e-24 87.7 12.3 1.7 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Fic PF02661.18 EPE33810.1 - 5.6e-16 59.2 0.0 1.1e-15 58.3 0.0 1.4 1 0 0 1 1 1 1 Fic/DOC family DUF543 PF04418.12 EPE33810.1 - 0.12 12.4 0.5 0.25 11.4 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Sugar_tr PF00083.24 EPE33813.1 - 2.1e-103 346.6 22.5 2.5e-103 346.4 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE33813.1 - 2.2e-17 63.0 61.5 9.9e-16 57.6 32.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 EPE33813.1 - 0.0028 17.8 1.4 0.0028 17.8 1.4 3.7 3 1 0 4 4 4 1 Protein of unknown function (DUF2530) Phage_holin_3_2 PF04550.12 EPE33813.1 - 0.079 13.5 0.6 0.079 13.5 0.6 2.7 3 0 0 3 3 3 0 Phage holin family 2 LapA_dom PF06305.11 EPE33813.1 - 7.7 6.4 6.1 2.1 8.2 0.3 3.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain AAA PF00004.29 EPE33815.1 - 4.7e-16 59.4 0.0 9e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPE33815.1 - 0.0016 18.7 0.5 0.27 11.5 0.1 2.9 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EPE33815.1 - 0.0023 18.3 0.0 0.0051 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_lid_6 PF17866.1 EPE33815.1 - 0.015 15.4 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA lid domain AAA_5 PF07728.14 EPE33815.1 - 0.017 15.1 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) LIN37 PF15306.6 EPE33817.1 - 0.0043 17.3 0.1 0.005 17.1 0.1 1.1 1 0 0 1 1 1 1 LIN37 Ecm29 PF13001.7 EPE33817.1 - 0.0067 15.2 0.1 0.0075 15.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome stabiliser DUF3560 PF12083.8 EPE33818.1 - 5.6 7.1 11.1 3.8 7.7 8.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) HDAC4_Gln PF12203.8 EPE33819.1 - 0.15 12.3 2.5 0.35 11.1 2.5 1.7 1 1 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 SH3BP5 PF05276.14 EPE33822.1 - 0.0014 18.5 0.3 0.0015 18.3 0.3 1.0 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) Exonuc_VII_S PF02609.16 EPE33822.1 - 0.0018 18.3 1.1 0.0027 17.7 0.6 1.5 1 1 0 1 1 1 1 Exonuclease VII small subunit OEP PF02321.18 EPE33822.1 - 0.02 14.7 1.1 0.023 14.5 1.1 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein Flagellin_N PF00669.20 EPE33823.1 - 0.012 15.8 0.1 0.014 15.5 0.1 1.0 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region SNARE PF05739.19 EPE33823.1 - 0.025 14.5 0.7 1.1 9.4 0.6 2.1 2 0 0 2 2 2 0 SNARE domain Cep57_CLD PF14073.6 EPE33823.1 - 0.042 13.9 1.7 0.047 13.7 1.7 1.1 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DUF3584 PF12128.8 EPE33823.1 - 0.055 11.0 0.4 0.056 11.0 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FH2 PF02181.23 EPE33823.1 - 0.1 11.7 0.2 0.11 11.6 0.2 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Spc7 PF08317.11 EPE33823.1 - 0.14 11.0 1.3 0.17 10.8 1.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DHR10 PF18595.1 EPE33823.1 - 0.17 11.9 4.2 0.73 9.9 4.3 1.8 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Pyr_redox_2 PF07992.14 EPE33824.1 - 6.9e-25 87.9 0.6 1.1e-24 87.2 0.6 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE33824.1 - 1.3e-15 57.7 2.5 4.3e-14 52.8 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE33824.1 - 0.0009 18.6 3.3 0.013 14.8 0.1 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE33824.1 - 0.04 12.6 1.3 2.5 6.7 0.5 2.3 1 1 1 2 2 2 0 HI0933-like protein K_oxygenase PF13434.6 EPE33824.1 - 0.049 12.8 0.2 1.2 8.2 0.1 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EPE33824.1 - 0.096 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 EPE33824.1 - 0.15 11.6 5.9 0.39 10.2 0.5 3.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EPE33824.1 - 2.3 7.4 8.4 5.2 6.3 3.6 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain zf-CCCH_4 PF18044.1 EPE33825.1 - 1.5 8.7 7.1 2.7 7.9 2.8 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger Cnd3 PF12719.7 EPE33826.1 - 4.8e-92 308.3 4.2 7e-92 307.7 1.8 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EPE33826.1 - 3.6e-09 36.9 10.2 5.7e-05 23.4 1.8 5.4 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EPE33826.1 - 5.3e-08 32.5 8.6 0.16 12.3 0.0 7.6 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 EPE33826.1 - 0.00052 20.1 0.7 2.1 8.4 0.0 5.4 5 2 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 PALP PF00291.25 EPE33827.1 - 1.1e-66 225.3 0.1 1.3e-66 225.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme YtxH PF12732.7 EPE33828.1 - 0.13 12.8 0.4 0.37 11.3 0.1 1.9 2 0 0 2 2 2 0 YtxH-like protein Ribosomal_L19 PF01245.20 EPE33829.1 - 6.9e-15 54.9 0.2 1.1e-14 54.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 Peptidase_M13_N PF05649.13 EPE33830.1 - 4.2e-75 253.8 0.0 5.5e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EPE33830.1 - 2.6e-54 183.9 0.0 5.5e-54 182.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 DUF1816 PF08846.10 EPE33831.1 - 6.8e-05 22.8 4.9 1.3 9.1 0.0 4.0 1 1 3 4 4 4 3 Domain of unknown function (DUF1816) DUF1421 PF07223.11 EPE33831.1 - 0.0015 18.3 0.0 14 5.6 0.0 3.9 4 0 0 4 4 4 1 UBA-like domain (DUF1421) SAE2 PF08573.10 EPE33831.1 - 0.0062 17.6 0.2 0.0083 17.2 0.2 1.2 1 0 0 1 1 1 1 DNA repair protein endonuclease SAE2/CtIP C-terminus PurL_C PF16904.5 EPE33831.1 - 0.01 16.1 0.2 25 5.2 0.0 3.7 1 1 3 4 4 4 0 Phosphoribosylformylglycinamidine synthase II C-terminus PagP PF07017.11 EPE33831.1 - 0.072 12.5 0.6 6.2 6.2 0.0 2.2 1 1 1 2 2 2 0 Antimicrobial peptide resistance and lipid A acylation protein PagP DUF1657 PF07870.11 EPE33831.1 - 0.24 11.3 4.6 15 5.6 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1657) TRAM1 PF08390.11 EPE33831.1 - 0.86 9.3 7.5 7.6e+02 -0.1 7.5 3.7 1 1 0 1 1 1 0 TRAM1-like protein DUF3328 PF11807.8 EPE33832.1 - 1.1e-59 201.9 0.1 1.4e-59 201.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) EF-hand_7 PF13499.6 EPE33832.1 - 0.075 13.5 0.0 0.27 11.7 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair DUF4048 PF13257.6 EPE33833.1 - 7.9e-16 58.7 10.5 7.9e-16 58.7 10.5 4.3 2 1 2 4 4 4 2 Domain of unknown function (DUF4048) TPR_MLP1_2 PF07926.12 EPE33833.1 - 0.018 15.1 3.6 0.039 14.0 3.6 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Bap31_Bap29_C PF18035.1 EPE33833.1 - 0.025 14.6 4.0 0.044 13.8 4.0 1.4 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain DNA_ligase_A_N PF04675.14 EPE33834.1 - 3.1e-10 40.7 0.0 7.3e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus Carb_anhydrase PF00194.21 EPE33835.1 - 3.1e-18 66.2 0.1 4.5e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase NUDIX PF00293.28 EPE33836.1 - 5.8e-16 58.7 0.4 2.2e-15 56.8 0.4 1.8 2 0 0 2 2 2 1 NUDIX domain NUDIX-like PF09296.11 EPE33836.1 - 7.1e-14 52.3 0.0 7.9e-13 49.0 0.0 2.2 2 1 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 EPE33836.1 - 4.2e-08 32.7 0.5 8.1e-08 31.8 0.5 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain MPM1 PF17234.2 EPE33838.1 - 0.0032 17.7 4.7 0.0067 16.7 4.7 1.5 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 SPATIAL PF15256.6 EPE33838.1 - 0.036 14.4 0.9 0.061 13.7 0.9 1.4 1 0 0 1 1 1 0 SPATIAL Endomucin PF07010.12 EPE33838.1 - 7.2 6.5 14.1 12 5.8 14.1 1.2 1 0 0 1 1 1 0 Endomucin Glyco_hydro_61 PF03443.14 EPE33840.1 - 1.2e-48 165.7 0.0 1.5e-48 165.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ERCC3_RAD25_C PF16203.5 EPE33841.1 - 5.3e-121 402.5 0.1 1.1e-120 401.5 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EPE33841.1 - 2.3e-29 102.1 0.0 4.5e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE33841.1 - 5.7e-15 55.7 0.1 1.5e-14 54.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EPE33841.1 - 1.3e-11 44.9 0.2 3.3e-11 43.5 0.2 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EPE33841.1 - 1.8e-08 33.5 0.0 2.5e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HypA PF01155.19 EPE33842.1 - 0.006 16.6 0.5 0.0075 16.3 0.5 1.3 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 EPE33842.1 - 0.0082 16.0 4.9 0.45 10.5 0.5 2.9 3 0 0 3 3 3 2 zinc-ribbon domain zf-FPG_IleRS PF06827.14 EPE33842.1 - 0.018 14.9 0.6 0.018 14.9 0.6 1.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.10 EPE33842.1 - 0.028 14.5 4.6 0.049 13.8 4.6 1.4 1 0 0 1 1 1 0 Zinc ribbon domain RNHCP PF12647.7 EPE33842.1 - 0.03 14.3 0.3 0.031 14.2 0.3 1.3 1 0 0 1 1 1 0 RNHCP domain YHS PF04945.13 EPE33842.1 - 0.031 14.4 1.9 0.059 13.5 1.9 1.4 1 0 0 1 1 1 0 YHS domain zinc_ribbon_9 PF14369.6 EPE33842.1 - 0.044 14.0 2.7 0.11 12.8 2.7 1.8 1 1 0 1 1 1 0 zinc-ribbon DpnI PF06044.12 EPE33842.1 - 0.086 12.5 0.3 0.089 12.4 0.3 1.2 1 0 0 1 1 1 0 Dam-replacing family C1_4 PF07975.12 EPE33842.1 - 0.42 10.9 4.8 6.3 7.1 5.1 2.1 1 1 0 1 1 1 0 TFIIH C1-like domain Proteasome PF00227.26 EPE33843.1 - 5.2e-55 185.9 0.1 7e-55 185.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EPE33843.1 - 5.9e-13 48.2 0.3 2e-12 46.5 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 EPE33843.1 - 0.11 12.3 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) FAD-oxidase_C PF02913.19 EPE33844.1 - 2.6e-55 187.8 0.0 3.8e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EPE33844.1 - 1.3e-34 118.9 0.7 2.7e-34 117.9 0.7 1.5 1 0 0 1 1 1 1 FAD binding domain Turandot PF07240.11 EPE33844.1 - 0.17 11.9 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot LemA PF04011.12 EPE33844.1 - 0.17 11.7 0.0 0.56 10.1 0.0 1.8 2 0 0 2 2 2 0 LemA family Ferritin_2 PF13668.6 EPE33845.1 - 2.9e-08 34.0 0.1 4.2e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain CoA_transf_3 PF02515.17 EPE33846.1 - 1.5e-67 228.3 0.0 1.9e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III PRIMA1 PF16101.5 EPE33847.1 - 2 8.5 5.2 2.3 8.3 5.2 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 EPE33847.1 - 2.4 7.6 3.8 2.4 7.5 3.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Dynamin_M PF01031.20 EPE33848.1 - 2.2e-101 338.8 0.0 4.2e-101 337.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EPE33848.1 - 5.3e-56 189.3 0.0 9.9e-56 188.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EPE33848.1 - 3.5e-30 104.0 4.2 7.7e-30 102.9 4.2 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EPE33848.1 - 6.1e-05 23.1 0.2 0.00038 20.5 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EPE33848.1 - 0.052 13.2 0.5 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain PfkB PF00294.24 EPE33849.1 - 3.3e-54 184.3 0.5 3.8e-54 184.1 0.5 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase WD40 PF00400.32 EPE33850.1 - 6e-23 80.7 9.4 2.1e-06 28.3 0.3 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE33850.1 - 7.8e-17 61.4 0.1 0.0021 18.3 0.0 6.2 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 EPE33850.1 - 0.00011 22.1 0.3 0.0024 17.8 0.0 2.7 2 1 1 3 3 3 1 WD domain, G-beta repeat eIF2A PF08662.11 EPE33850.1 - 0.00026 21.0 0.1 0.1 12.5 0.0 3.1 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EPE33850.1 - 0.0036 16.3 0.1 0.036 13.0 0.0 2.5 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 EPE33850.1 - 0.0062 16.3 0.0 0.47 10.2 0.0 3.2 2 1 2 4 4 4 2 Lipoprotein LpqB beta-propeller domain Coatomer_WDAD PF04053.14 EPE33850.1 - 0.0073 15.4 0.0 0.028 13.5 0.0 2.0 2 1 1 3 3 3 1 Coatomer WD associated region WD40_like PF17005.5 EPE33850.1 - 0.044 13.1 0.0 15 4.8 0.0 2.9 1 1 1 3 3 3 0 WD40-like domain Nbas_N PF15492.6 EPE33850.1 - 0.047 13.0 0.0 1.1 8.5 0.0 2.5 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Str_synth PF03088.16 EPE33850.1 - 0.12 12.5 0.0 27 5.0 0.0 3.5 3 1 1 4 4 4 0 Strictosidine synthase ATP-synt_ab PF00006.25 EPE33851.1 - 8.2e-110 365.5 0.0 1.1e-109 365.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EPE33851.1 - 3.5e-47 159.2 0.0 6.4e-47 158.4 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EPE33851.1 - 6.6e-15 55.4 4.0 1.4e-14 54.4 4.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain F_actin_bind PF08919.10 EPE33851.1 - 0.052 13.7 0.1 0.66 10.1 0.1 2.3 2 0 0 2 2 2 0 F-actin binding adh_short PF00106.25 EPE33852.1 - 3.9e-18 65.6 0.3 7.1e-18 64.8 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE33852.1 - 2.4e-10 40.4 0.2 3.7e-10 39.7 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE33852.1 - 5.8e-08 32.8 0.2 1.1e-07 32.0 0.2 1.4 1 0 0 1 1 1 1 KR domain Bac_rhodopsin PF01036.18 EPE33853.1 - 5.8e-49 166.7 19.3 6.8e-49 166.4 19.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MerC PF03203.14 EPE33853.1 - 0.047 14.1 9.7 0.092 13.2 4.7 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein Heliorhodopsin PF18761.1 EPE33853.1 - 1.6 7.9 12.2 0.023 14.0 3.4 2.1 1 1 0 2 2 2 0 Heliorhodopsin DUF3810 PF12725.7 EPE33853.1 - 2.6 7.3 6.6 6.3 6.0 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF4131 PF13567.6 EPE33853.1 - 4.2 7.0 7.5 3 7.5 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) ACT_7 PF13840.6 EPE33854.1 - 2.4e-19 68.9 0.1 5.6e-17 61.3 0.0 2.7 3 0 0 3 3 3 2 ACT domain CTD_bind PF04818.13 EPE33855.1 - 6.8e-15 55.7 0.7 2.9e-14 53.6 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. DUF4748 PF15932.5 EPE33856.1 - 7.7e-27 92.8 0.9 1.2e-26 92.1 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) Exo_endo_phos PF03372.23 EPE33857.1 - 1.5e-10 41.0 0.3 1.1e-09 38.1 0.2 2.3 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.6 EPE33857.1 - 0.053 13.6 0.3 0.32 11.1 0.0 2.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 EPE33857.1 - 2.1 9.4 5.1 3.7 8.6 0.2 3.9 4 1 1 5 5 5 0 WD domain, G-beta repeat GFA PF04828.14 EPE33858.1 - 1.2e-09 38.3 1.4 1.2e-09 38.3 1.4 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4_3 PF13920.6 EPE33859.1 - 4.5e-09 36.0 8.6 4.5e-09 36.0 8.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE33859.1 - 1.9e-08 34.5 11.8 1.9e-08 34.5 11.8 2.5 3 0 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EPE33859.1 - 1.8e-07 31.1 5.5 1.8e-07 31.1 5.5 2.1 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EPE33859.1 - 5e-07 29.5 8.8 5e-07 29.5 8.8 3.0 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EPE33859.1 - 1.4e-06 28.1 10.1 1.4e-06 28.1 10.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE33859.1 - 2.9e-06 27.0 12.0 1.7e-05 24.6 12.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE33859.1 - 3.1e-06 27.0 9.4 3.1e-06 27.0 9.4 2.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EPE33859.1 - 0.00013 22.1 10.2 0.00058 20.0 10.2 2.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EPE33859.1 - 0.0011 18.7 15.0 0.012 15.4 4.0 3.2 2 1 1 3 3 3 2 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EPE33859.1 - 0.52 10.4 6.4 2 8.5 6.4 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.20 EPE33859.1 - 0.69 9.7 8.9 2 8.2 8.9 1.9 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.7 EPE33859.1 - 1.2 9.4 12.4 7.5 6.9 12.4 2.5 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EPE33859.1 - 1.5 8.7 8.6 0.38 10.6 4.6 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-WRNIP1_ubi PF18279.1 EPE33859.1 - 7.9 7.4 7.0 41 5.1 0.3 3.0 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain PrpF PF04303.13 EPE33860.1 - 4.5e-101 338.5 0.6 5.4e-94 315.2 0.1 2.0 2 0 0 2 2 2 2 PrpF protein MFS_1 PF07690.16 EPE33861.1 - 1.7e-33 116.1 21.5 2.4e-33 115.5 21.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EPE33861.1 - 2.7e-07 30.2 5.7 2.7e-07 30.2 5.7 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Orthoreo_P10 PF07204.11 EPE33861.1 - 0.11 12.5 0.8 4.2 7.4 0.0 3.0 3 0 0 3 3 3 0 Orthoreovirus membrane fusion protein p10 Sugar_tr PF00083.24 EPE33862.1 - 2e-124 415.9 32.1 2.3e-124 415.7 32.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE33862.1 - 9.2e-28 97.2 30.2 9.2e-28 97.2 30.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RNPHF PF08080.12 EPE33862.1 - 0.1 12.6 0.1 0.84 9.6 0.1 2.4 2 0 0 2 2 2 0 RNPHF zinc finger SecE PF00584.20 EPE33862.1 - 0.11 12.4 0.1 0.11 12.4 0.1 4.4 7 0 0 7 7 7 0 SecE/Sec61-gamma subunits of protein translocation complex DUF4342 PF14242.6 EPE33862.1 - 0.14 12.1 0.6 1.1 9.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) Fungal_trans PF04082.18 EPE33863.1 - 4.2e-25 88.3 0.5 6.5e-25 87.7 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.27 EPE33864.1 - 3.8e-55 183.8 9.6 6e-20 71.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 EPE33864.1 - 0.14 12.5 12.3 17 5.8 2.6 3.1 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family CbtA PF09490.10 EPE33864.1 - 3.3 7.4 7.0 2.9 7.6 1.6 2.7 2 2 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) E1_DerP2_DerF2 PF02221.15 EPE33865.1 - 0.00068 20.1 0.0 0.0014 19.1 0.0 1.5 1 1 0 1 1 1 1 ML domain CDCA PF18484.1 EPE33866.1 - 0.0083 16.0 0.3 0.0093 15.9 0.3 1.0 1 0 0 1 1 1 1 Cadmium carbonic anhydrase repeat zf-C2H2_2 PF12756.7 EPE33866.1 - 0.012 15.9 0.2 0.013 15.8 0.2 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-CpG_bind_C PF12269.8 EPE33866.1 - 0.025 14.4 0.2 0.025 14.4 0.2 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain zf-met2 PF12907.7 EPE33866.1 - 0.027 14.6 3.9 0.067 13.3 3.4 1.9 1 1 0 1 1 1 0 Zinc-binding DUF2757 PF10955.8 EPE33866.1 - 0.089 13.1 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) TrkH PF02386.16 EPE33868.1 - 2.2e-149 498.1 6.0 7.1e-149 496.5 2.9 2.0 2 0 0 2 2 2 2 Cation transport protein EHN PF06441.12 EPE33870.1 - 1.2e-26 93.2 0.1 2e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Hid1 PF12722.7 EPE33871.1 - 1.7e-297 989.0 0.0 2e-297 988.8 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EPE33871.1 - 7.4e-104 348.4 0.0 9.6e-104 348.0 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.11 EPE33871.1 - 1.7e-25 89.6 0.0 4e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore complex component AMP-binding PF00501.28 EPE33872.1 - 3.3e-14 52.3 0.0 4.2e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme PhoD PF09423.10 EPE33873.1 - 1e-43 149.7 0.1 3.5e-43 148.0 0.0 1.8 2 1 0 2 2 2 1 PhoD-like phosphatase EF-hand_7 PF13499.6 EPE33874.1 - 5.3e-26 90.9 1.9 5.6e-17 62.0 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EPE33874.1 - 2.3e-24 83.1 4.1 4.8e-09 35.1 0.6 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EPE33874.1 - 1.7e-19 68.0 2.4 3.3e-07 29.7 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EPE33874.1 - 3.9e-17 61.8 5.1 9e-13 47.9 0.5 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EPE33874.1 - 2.4e-10 39.4 6.6 3.1e-05 23.2 0.7 2.9 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EPE33874.1 - 4.4e-10 39.7 2.9 2.1e-08 34.4 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain UPF0154 PF03672.13 EPE33874.1 - 6.4e-06 26.1 0.0 0.052 13.6 0.0 2.7 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 EPE33874.1 - 1.1e-05 26.3 0.0 2e-05 25.4 0.0 1.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 EPE33874.1 - 0.00014 21.8 1.9 0.0034 17.3 0.3 2.6 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 EPE33874.1 - 0.013 15.9 0.1 0.092 13.1 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 EPE33874.1 - 0.034 14.5 0.0 0.086 13.2 0.0 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Multi_ubiq PF14452.6 EPE33874.1 - 0.1 12.9 0.0 16 5.9 0.0 2.6 2 1 0 2 2 2 0 Multiubiquitin Unstab_antitox PF09720.10 EPE33874.1 - 0.12 12.5 1.0 0.64 10.1 0.0 2.4 2 0 0 2 2 2 0 Putative addiction module component LSM PF01423.22 EPE33877.1 - 1.4e-16 59.9 0.0 1.9e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EPE33877.1 - 0.00072 19.7 0.0 0.00088 19.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain PPR_2 PF13041.6 EPE33878.1 - 7.6e-17 61.3 0.5 0.0015 18.7 0.0 6.5 3 2 4 7 7 7 4 PPR repeat family PPR_3 PF13812.6 EPE33878.1 - 4.6e-12 45.8 0.0 6e-05 23.0 0.0 4.5 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 EPE33878.1 - 1.2e-09 37.8 4.8 0.047 13.9 0.2 6.6 7 0 0 7 7 7 2 PPR repeat PPR_1 PF12854.7 EPE33878.1 - 1.6e-08 34.1 2.9 0.07 12.9 0.0 5.1 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 EPE33878.1 - 1.6e-06 27.7 0.0 0.05 13.0 0.1 3.1 2 1 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EPE33878.1 - 8.9e-05 23.0 0.1 11 7.1 0.0 5.3 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPE33878.1 - 0.0076 16.3 0.4 3.7 7.9 0.1 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EPE33878.1 - 0.011 16.0 0.0 16 5.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EPE33878.1 - 0.021 15.3 0.1 15 6.2 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EPE33878.1 - 0.046 13.8 0.2 2.9 8.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPE33878.1 - 0.049 13.5 0.6 59 3.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EPE33878.1 - 0.18 11.7 1.2 19 5.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat C5HCH PF17982.1 EPE33879.1 - 0.0052 16.9 0.9 0.018 15.2 0.9 1.9 1 0 0 1 1 1 1 NSD Cys-His rich domain zf-C2H2_4 PF13894.6 EPE33879.1 - 0.044 14.6 21.1 0.96 10.5 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EPE33879.1 - 0.072 13.6 0.7 0.072 13.6 0.7 3.8 2 1 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 EPE33879.1 - 0.11 12.2 17.4 0.32 10.8 0.7 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain DUF1478 PF07349.11 EPE33879.1 - 0.19 11.6 0.1 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1478) zf-C2H2_aberr PF17017.5 EPE33879.1 - 2.4 8.3 8.9 0.31 11.2 3.1 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger Ribosomal_L13 PF00572.18 EPE33880.1 - 6.9e-41 139.4 0.0 1.4e-40 138.4 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L13 HMA PF00403.26 EPE33881.1 - 1.4e-12 47.9 0.0 2.3e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain TPR_1 PF00515.28 EPE33882.1 - 1.4e-14 53.2 3.6 5.7e-07 29.1 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EPE33882.1 - 2.4e-13 49.1 3.3 2e-05 24.4 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EPE33882.1 - 4.9e-09 36.3 0.0 3.6e-05 23.9 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPE33882.1 - 1.2e-08 34.5 0.1 0.00022 21.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat PB1 PF00564.24 EPE33882.1 - 6.5e-07 29.2 0.5 1.2e-06 28.4 0.5 1.5 1 0 0 1 1 1 1 PB1 domain TPR_7 PF13176.6 EPE33882.1 - 7.8e-07 28.7 0.1 4.9e-05 23.1 0.1 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EPE33882.1 - 1.2e-06 28.0 0.8 7.8e-05 22.3 0.1 3.5 2 1 1 3 3 3 1 TPR repeat TPR_6 PF13174.6 EPE33882.1 - 2.4e-05 24.7 0.2 9.6 7.1 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EPE33882.1 - 0.0012 18.9 0.0 0.53 10.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPE33882.1 - 0.0039 17.8 0.3 0.029 15.0 0.2 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EPE33882.1 - 0.047 14.5 0.0 0.53 11.2 0.0 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EPE33882.1 - 0.1 13.1 0.0 3.7 8.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPE33882.1 - 0.23 11.4 1.5 2.6 8.0 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Hemerythrin PF01814.23 EPE33883.1 - 2.7e-10 41.0 4.7 2.7e-10 41.0 4.7 1.6 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain VSG_B PF13206.6 EPE33883.1 - 0.061 12.6 0.7 0.11 11.8 0.1 1.6 1 1 0 1 1 1 0 Trypanosomal VSG domain NTP_transf_3 PF12804.7 EPE33884.1 - 2.2e-07 31.4 0.0 3.6e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 MobA-like NTP transferase domain MoeA_N PF03453.17 EPE33885.1 - 7.2e-22 77.8 0.0 8.5e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) SET PF00856.28 EPE33886.1 - 3.9e-11 43.6 0.6 8.7e-10 39.2 0.6 2.3 1 1 0 1 1 1 1 SET domain HET PF06985.11 EPE33887.1 - 7.2e-33 114.0 0.4 1.5e-32 113.0 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Uricase PF01014.18 EPE33888.1 - 1.6e-78 261.3 0.5 7.2e-40 136.3 0.8 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.6 EPE33889.1 - 4.8e-130 433.9 1.9 4.8e-130 433.9 1.9 2.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 EPE33889.1 - 1.9e-39 133.6 1.2 7.1e-37 125.3 0.2 4.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EPE33889.1 - 1.8e-37 128.0 0.1 6.5e-35 119.8 0.0 4.4 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 EPE33889.1 - 1.1e-29 102.5 0.4 4.1e-28 97.4 0.1 3.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 EPE33889.1 - 5.6e-18 64.8 7.8 1.6e-17 63.4 7.8 1.7 1 0 0 1 1 1 1 Hr1 repeat DUF724 PF05266.14 EPE33889.1 - 0.01 15.7 4.1 0.027 14.3 4.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Uds1 PF15456.6 EPE33889.1 - 0.024 14.8 6.1 0.073 13.2 6.1 1.8 1 0 0 1 1 1 0 Up-regulated During Septation eIF-3c_N PF05470.12 EPE33890.1 - 4.5e-172 573.5 24.4 1.8e-141 472.4 1.6 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EPE33890.1 - 1.7e-14 54.2 0.9 1e-13 51.7 0.1 2.7 2 0 0 2 2 2 1 PCI domain AAR2 PF05282.11 EPE33892.1 - 1.9e-62 211.8 0.0 1.9e-62 211.8 0.0 1.8 2 0 0 2 2 2 1 AAR2 protein DUF3934 PF13070.6 EPE33892.1 - 0.15 12.5 0.1 0.35 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3934) Ribosomal_S11 PF00411.19 EPE33893.1 - 4.5e-46 155.8 1.3 5.6e-46 155.5 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EPE33893.1 - 0.065 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) PDH PF02153.17 EPE33894.1 - 7.2e-14 51.4 0.0 1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 EPE33894.1 - 1.9e-07 31.4 0.0 6e-07 29.8 0.0 1.8 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EPE33894.1 - 6.5e-05 23.4 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EPE33894.1 - 0.00011 21.9 0.0 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EPE33894.1 - 0.00078 18.8 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EPE33894.1 - 0.011 15.6 0.0 0.052 13.4 0.0 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SCAB-Ig PF16709.5 EPE33894.1 - 0.029 14.4 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Ig domain of plant-specific actin-binding protein Shikimate_DH PF01488.20 EPE33894.1 - 0.07 13.2 0.0 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EPE33894.1 - 0.071 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.12 EPE33894.1 - 0.12 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ribosomal_S9 PF00380.19 EPE33895.1 - 4.5e-34 117.6 0.2 5.1e-34 117.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EAP30 PF04157.16 EPE33896.1 - 8.4e-75 251.1 0.1 9.4e-75 250.9 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family YabA PF06156.13 EPE33897.1 - 0.28 11.8 1.5 4.2 8.1 0.3 2.2 1 1 1 2 2 2 0 Initiation control protein YabA FOXP-CC PF16159.5 EPE33897.1 - 0.29 11.8 1.6 0.46 11.1 0.2 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 EPE33897.1 - 0.77 10.3 2.6 0.51 10.9 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3384 PF11864.8 EPE33898.1 - 5.4e-130 434.5 0.1 2e-128 429.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 EPE33898.1 - 4.6e-54 182.8 0.0 8.7e-54 181.9 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 EPE33898.1 - 8.2e-42 143.6 7.2 6e-39 134.1 0.7 3.3 3 0 0 3 3 3 3 Tuberin CAS_CSE1 PF03378.15 EPE33899.1 - 3.5e-188 625.6 0.0 1.4e-187 623.6 0.0 2.0 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EPE33899.1 - 5.1e-160 532.3 0.3 7.4e-160 531.8 0.3 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 EPE33899.1 - 2.5e-15 56.2 0.1 1.1e-13 50.9 0.1 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EPE33899.1 - 0.014 15.4 2.1 2.4 8.2 0.1 4.3 4 1 0 4 4 4 0 Exportin 1-like protein DsbG_N PF18257.1 EPE33899.1 - 0.11 12.6 0.0 3.3 7.9 0.0 3.0 3 0 0 3 3 3 0 Disulfide isomerase DsbG N-terminal Glyco_hydro_10 PF00331.20 EPE33900.1 - 1.3e-100 336.7 1.0 1.5e-100 336.4 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 EPE33900.1 - 3.4e-07 30.1 9.9 8.5e-07 28.8 9.9 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Phos_pyr_kin PF08543.12 EPE33902.1 - 6.3e-83 277.9 1.8 6.3e-83 277.9 1.8 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EPE33902.1 - 1e-48 165.9 1.1 1.6e-44 152.3 1.5 2.3 2 0 0 2 2 2 2 TENA/THI-4/PQQC family PfkB PF00294.24 EPE33902.1 - 3.7e-07 29.7 0.0 7.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 EPE33902.1 - 0.02 14.3 0.6 0.22 10.9 0.1 2.3 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 EPE33902.1 - 0.024 14.1 2.7 0.032 13.7 1.4 1.9 2 1 0 2 2 2 0 Carbohydrate kinase HECT PF00632.25 EPE33903.1 - 1.5e-81 274.3 0.0 3.3e-81 273.1 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 EPE33903.1 - 0.002 17.8 0.1 0.0084 15.8 0.1 2.2 1 0 0 1 1 1 1 IQ calmodulin-binding motif PG_binding_2 PF08823.11 EPE33903.1 - 0.0051 17.1 0.0 0.016 15.5 0.0 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Piwi PF02171.17 EPE33904.1 - 2.2e-75 253.7 0.0 3.1e-75 253.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 EPE33904.1 - 9e-16 57.3 0.3 1.9e-15 56.3 0.3 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 EPE33904.1 - 1.5e-11 45.1 0.0 2.7e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 EPE33904.1 - 6.9e-07 29.5 0.0 1.5e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 EPE33904.1 - 7.6e-07 29.0 0.0 2.2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EPE33904.1 - 0.0003 21.0 0.0 0.00065 19.9 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute MFS_1 PF07690.16 EPE33905.1 - 2.9e-40 138.3 47.5 2.9e-40 138.3 47.5 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE33905.1 - 3.3e-13 48.9 23.6 9.2e-13 47.5 23.6 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cren7 PF11520.8 EPE33907.1 - 0.11 12.4 1.1 0.18 11.7 1.1 1.3 1 0 0 1 1 1 0 Chromatin protein Cren7 Cyclin_N PF00134.23 EPE33909.1 - 5.7e-15 55.2 0.1 5.2e-14 52.1 0.0 2.4 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin PF08613.11 EPE33909.1 - 1e-07 32.5 0.0 2.7e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Cyclin PET117 PF15786.5 EPE33909.1 - 3.4 8.0 7.4 6.2 7.2 7.4 1.4 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial HARP PF07443.13 EPE33911.1 - 0.19 11.4 0.0 0.51 10.0 0.0 1.6 1 0 0 1 1 1 0 HepA-related protein (HARP) Complex1_LYR_2 PF13233.6 EPE33912.1 - 6.6e-22 78.1 0.5 7.7e-22 77.9 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like MMR_HSR1 PF01926.23 EPE33913.1 - 2.5e-19 69.4 0.0 3.8e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EPE33913.1 - 3.3e-06 26.8 0.0 0.00016 21.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EPE33913.1 - 9.8e-06 25.7 0.0 0.0029 17.7 0.1 2.2 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 EPE33913.1 - 3.8e-05 23.7 0.2 0.0021 18.0 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 EPE33913.1 - 0.0018 17.7 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 EPE33913.1 - 0.0022 17.5 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.18 EPE33913.1 - 0.0032 16.8 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 Septin FeoB_N PF02421.18 EPE33913.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 EPE33913.1 - 0.014 15.6 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ENTH PF01417.20 EPE33914.1 - 1.2e-49 167.5 0.1 2.1e-49 166.7 0.1 1.4 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 EPE33914.1 - 0.001 18.8 4.5 0.028 14.3 0.3 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.16 EPE33914.1 - 0.0022 17.1 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 EPE33914.1 - 0.0029 17.4 0.0 0.005 16.7 0.0 1.3 1 0 0 1 1 1 1 VHS domain AIDA PF16168.5 EPE33914.1 - 0.023 14.7 0.2 0.055 13.6 0.2 1.6 1 0 0 1 1 1 0 Adhesin of bacterial autotransporter system, probable stalk DUF4264 PF14084.6 EPE33914.1 - 0.026 14.2 0.1 0.049 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Tim54 PF11711.8 EPE33914.1 - 1.2 7.8 12.8 0.012 14.4 5.1 1.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 EF-hand_7 PF13499.6 EPE33915.1 - 1.2e-16 60.9 1.9 4.5e-10 39.8 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EPE33915.1 - 3e-15 54.5 7.2 9.9e-07 27.9 0.3 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EPE33915.1 - 2.5e-14 51.9 4.3 1.6e-06 27.5 0.4 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EPE33915.1 - 5.2e-14 51.8 4.6 3.5e-09 36.4 0.7 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 EPE33915.1 - 0.0017 18.6 0.1 0.015 15.6 0.0 2.3 2 1 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 EPE33915.1 - 0.0019 18.1 0.0 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 EPE33915.1 - 0.0029 17.0 7.3 0.31 10.6 0.3 3.2 3 0 0 3 3 3 2 EF hand DUF150 PF02576.17 EPE33915.1 - 0.046 14.1 0.1 0.083 13.3 0.1 1.4 1 0 0 1 1 1 0 RimP N-terminal domain Caleosin PF05042.13 EPE33915.1 - 0.16 11.9 0.0 7.3 6.5 0.0 2.1 2 0 0 2 2 2 0 Caleosin related protein Nup96 PF12110.8 EPE33916.1 - 1.1e-90 303.7 0.2 1.7e-90 303.1 0.2 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EPE33916.1 - 5.4e-53 179.1 0.0 9.3e-53 178.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EPE33916.1 - 2.5e-13 50.7 169.2 2e-08 34.9 41.7 12.6 3 2 9 12 12 12 8 Nucleoporin FG repeat region Mce4_CUP1 PF11887.8 EPE33917.1 - 0.033 13.7 0.6 0.38 10.2 0.2 2.1 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Baculo_PEP_C PF04513.12 EPE33917.1 - 0.88 9.6 4.3 13 5.8 0.0 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus A_deaminase PF00962.22 EPE33919.1 - 1.1e-20 74.2 0.0 7.1e-19 68.3 0.0 2.6 2 1 0 2 2 2 2 Adenosine/AMP deaminase A_deaminase_N PF08451.11 EPE33919.1 - 0.07 13.4 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal SRP40_C PF05022.12 EPE33920.1 - 1.4e-23 83.5 0.7 5.5e-23 81.6 0.7 2.1 1 0 0 1 1 1 1 SRP40, C-terminal domain Sec3_C PF09763.9 EPE33921.1 - 1.7e-231 770.5 0.1 2.1e-231 770.1 0.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 EPE33921.1 - 1.6e-27 95.4 0.0 3e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 EPE33921.1 - 0.00012 22.4 0.1 0.00046 20.5 0.1 2.0 1 0 0 1 1 1 1 Sec3 exocyst complex subunit Vps52 PF04129.12 EPE33921.1 - 0.00038 19.3 0.7 0.00096 18.0 0.7 1.6 1 0 0 1 1 1 1 Vps52 / Sac2 family GTP_EFTU PF00009.27 EPE33923.1 - 6.4e-60 202.0 0.3 1.3e-59 201.0 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EPE33923.1 - 6.8e-33 112.6 0.0 1.5e-32 111.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EPE33923.1 - 1.3e-32 112.1 0.0 4.8e-32 110.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EPE33923.1 - 5.8e-25 87.2 0.0 1.6e-23 82.5 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EPE33923.1 - 1.4e-14 54.2 0.1 4.5e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EPE33923.1 - 5.6e-06 26.2 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EPE33923.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase IMS PF00817.20 EPE33924.1 - 8e-41 139.5 0.6 1.7e-40 138.5 0.1 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 EPE33924.1 - 5.9e-14 52.8 0.1 1.4e-13 51.5 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EPE33924.1 - 0.0029 17.8 0.0 0.0089 16.3 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif RPEL PF02755.15 EPE33925.1 - 8.5e-30 101.6 22.7 2.5e-10 39.7 2.8 3.9 4 0 0 4 4 4 3 RPEL repeat Rotamase_3 PF13616.6 EPE33925.1 - 0.01 16.4 0.2 0.25 11.9 0.0 2.3 1 1 1 2 2 2 1 PPIC-type PPIASE domain Clr5 PF14420.6 EPE33927.1 - 1.7e-17 63.3 2.3 1.8e-17 63.3 0.4 2.1 2 0 0 2 2 2 1 Clr5 domain Ribosomal_S8 PF00410.19 EPE33929.1 - 3.9e-14 52.7 0.0 3.4e-13 49.7 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S8 Iso_dh PF00180.20 EPE33930.1 - 5.1e-97 325.1 0.1 7.8e-97 324.5 0.1 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NOA36 PF06524.12 EPE33931.1 - 3.8 6.7 15.0 7.3 5.8 15.0 1.4 1 0 0 1 1 1 0 NOA36 protein SET PF00856.28 EPE33933.1 - 7.1e-14 52.5 2.4 3.3e-12 47.1 0.6 3.0 2 1 0 2 2 2 1 SET domain EGF_3 PF12947.7 EPE33933.1 - 0.075 13.2 4.6 0.086 13.1 1.7 2.6 2 1 0 2 2 2 0 EGF domain SAF PF08666.12 EPE33933.1 - 0.21 12.2 0.0 1.6 9.4 0.0 2.2 2 0 0 2 2 2 0 SAF domain GST_N_2 PF13409.6 EPE33934.1 - 4.1e-09 36.6 0.0 7.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPE33934.1 - 2.3e-07 31.1 0.0 4.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EPE33934.1 - 5.2e-07 29.8 0.0 9.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EPE33934.1 - 1e-06 29.0 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EPE33934.1 - 1.1e-06 28.7 0.0 1.7e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPE33934.1 - 4.9e-05 23.3 0.1 0.00014 21.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Gal-bind_lectin PF00337.22 EPE33934.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Galactoside-binding lectin Glyco_hydro_92 PF07971.12 EPE33935.1 - 5.1e-120 401.5 0.0 7.6e-106 354.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EPE33935.1 - 1.1e-68 231.6 1.7 1.7e-68 231.1 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Gln-synt_C PF00120.24 EPE33936.1 - 1.3e-61 208.5 0.0 2.1e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 EPE33936.1 - 7.4e-17 62.0 0.2 4.3e-16 59.5 0.1 2.1 2 0 0 2 2 2 1 Amidohydrolase Gln-synt_N_2 PF16952.5 EPE33936.1 - 0.0081 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Bac_DnaA PF00308.18 EPE33936.1 - 0.044 13.6 0.1 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein FAD-SLDH PF12318.8 EPE33936.1 - 0.052 13.6 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase TMEM119 PF15724.5 EPE33937.1 - 0.0073 16.4 4.7 0.0073 16.4 4.7 2.6 1 1 0 2 2 2 1 TMEM119 family TctB PF07331.11 EPE33937.1 - 0.043 14.1 0.1 0.07 13.4 0.1 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF5305 PF17231.2 EPE33937.1 - 0.06 12.7 0.7 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF1180 PF06679.12 EPE33937.1 - 0.88 10.0 0.0 0.88 10.0 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1180) MGC-24 PF05283.11 EPE33937.1 - 1.5 9.2 4.0 0.47 10.9 0.4 1.9 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4381 PF14316.6 EPE33937.1 - 5.2 7.3 5.5 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) KH_1 PF00013.29 EPE33938.1 - 0.0018 18.1 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 KH domain MLANA PF14991.6 EPE33940.1 - 0.096 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A Aldo_ket_red PF00248.21 EPE33941.1 - 1.6e-41 142.4 0.0 2.1e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 EPE33942.1 - 2.3e-10 39.9 0.6 3.2e-10 39.5 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE33942.1 - 9.5e-09 35.2 10.3 1.6e-08 34.5 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NGP1NT PF08153.12 EPE33943.1 - 2e-48 163.8 0.1 3.8e-48 162.9 0.1 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EPE33943.1 - 7e-17 61.6 0.0 4.4e-13 49.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EPE33943.1 - 0.00026 20.5 0.1 0.0012 18.5 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EPE33943.1 - 0.0014 18.6 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 EPE33943.1 - 0.0016 17.9 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.23 EPE33943.1 - 0.022 14.8 3.2 1.3 9.1 0.0 3.5 3 1 1 4 4 4 0 Dynamin family BUD22 PF09073.10 EPE33943.1 - 8.8 5.5 16.7 15 4.8 16.7 1.3 1 0 0 1 1 1 0 BUD22 adh_short PF00106.25 EPE33946.1 - 8.9e-35 119.9 3.2 1.5e-19 70.3 0.4 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE33946.1 - 6.6e-27 94.6 0.3 3.6e-14 52.9 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE33946.1 - 1.5e-06 28.2 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE33946.1 - 0.084 12.3 0.2 0.18 11.3 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Rad4 PF03835.15 EPE33947.1 - 2.8e-16 59.5 2.9 6.8e-16 58.3 2.9 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EPE33947.1 - 6.1e-14 52.4 2.9 9e-14 51.9 1.5 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily Pex14_N PF04695.13 EPE33947.1 - 7.3 7.2 11.7 0.66 10.6 5.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TrkH PF02386.16 EPE33949.1 - 2e-100 336.7 7.7 1.3e-95 320.8 1.3 2.1 2 0 0 2 2 2 2 Cation transport protein Ion_trans_2 PF07885.16 EPE33949.1 - 3.9 7.5 10.6 0.93 9.5 6.0 2.4 2 0 0 2 2 2 0 Ion channel Ferritin_2 PF13668.6 EPE33950.1 - 0.13 12.4 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 Ferritin-like domain OAD_gamma PF04277.13 EPE33951.1 - 0.0098 16.5 0.0 0.012 16.1 0.0 1.1 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain Gram_pos_anchor PF00746.21 EPE33954.1 - 0.11 12.5 4.0 16 5.5 0.0 2.8 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Ribonuclease PF00545.20 EPE33955.1 - 2.8e-07 31.2 0.0 3.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 ribonuclease Como_SCP PF02248.16 EPE33955.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Small coat protein DUF3632 PF12311.8 EPE33956.1 - 9.4e-37 127.1 3.3 1.1e-36 126.9 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF1577 PF07614.11 EPE33957.1 - 0.044 12.9 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) FKBP_C PF00254.28 EPE33958.1 - 1.9e-30 105.0 0.0 2.9e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-ANAPC11 PF12861.7 EPE33959.1 - 1.8e-44 149.7 9.9 2e-44 149.5 9.9 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EPE33959.1 - 4.1e-21 75.0 12.6 5.7e-21 74.6 12.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EPE33959.1 - 1.3e-08 35.0 15.5 1.8e-07 31.3 15.5 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPE33959.1 - 2.5e-05 24.0 5.5 2.5e-05 24.0 5.5 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE33959.1 - 3.5e-05 23.7 10.7 0.00085 19.3 7.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EPE33959.1 - 0.00017 21.4 15.9 0.00089 19.1 15.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPE33959.1 - 0.00047 20.3 1.4 0.00047 20.3 1.4 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EPE33959.1 - 0.00084 19.5 16.2 0.0092 16.1 16.2 2.6 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 EPE33959.1 - 0.0017 18.2 7.9 0.0017 18.2 7.9 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE33959.1 - 0.0017 18.2 15.9 0.026 14.5 16.3 2.2 1 1 1 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EPE33959.1 - 0.0046 16.5 12.8 0.069 12.8 12.8 2.2 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 EPE33959.1 - 0.0049 16.7 5.3 0.0087 15.9 5.1 1.6 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 EPE33959.1 - 0.025 14.4 0.2 0.025 14.4 0.2 2.5 2 1 0 2 2 2 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 EPE33959.1 - 0.071 12.9 11.6 0.28 10.9 9.0 2.8 2 1 0 2 2 2 0 RING-like zinc finger zf-RING_4 PF14570.6 EPE33959.1 - 0.082 12.7 14.6 0.3 10.9 11.4 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EPE33959.1 - 0.094 12.6 14.0 0.15 11.9 10.2 2.2 1 1 2 3 3 3 0 Prokaryotic RING finger family 4 RINGv PF12906.7 EPE33959.1 - 0.16 12.1 12.4 0.28 11.4 11.4 2.0 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 EPE33959.1 - 0.54 10.6 14.6 0.61 10.4 12.2 2.1 1 1 1 2 2 2 0 RING-like domain UBZ_FAAP20 PF15750.5 EPE33959.1 - 0.58 10.1 6.0 2.4 8.2 0.8 2.6 2 1 0 2 2 2 0 Ubiquitin-binding zinc-finger UPF0506 PF11703.8 EPE33959.1 - 1.9 9.0 11.9 3.4 8.1 3.7 2.2 1 1 1 2 2 2 0 UPF0506 zf-C2H2_9 PF16293.5 EPE33959.1 - 2.5 8.0 5.4 10 6.1 0.0 3.2 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) DZR PF12773.7 EPE33959.1 - 4.8 7.3 13.6 3.8 7.6 6.0 2.3 1 1 1 2 2 2 0 Double zinc ribbon Rhodanese PF00581.20 EPE33960.1 - 3.6e-18 66.0 0.0 9.7e-11 42.1 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain Methyltransf_23 PF13489.6 EPE33961.1 - 1.9e-24 86.3 0.0 2.9e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE33961.1 - 3.2e-08 34.2 0.0 7.9e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE33961.1 - 2.1e-05 24.4 0.0 0.00043 20.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE33961.1 - 0.00017 22.2 0.0 0.00034 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EPE33961.1 - 0.00063 19.9 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 EPE33961.1 - 0.0056 17.4 0.0 0.045 14.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPE33961.1 - 0.04 13.5 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EPE33961.1 - 0.041 13.3 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 EPE33961.1 - 0.049 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.17 EPE33961.1 - 0.059 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 EPE33961.1 - 0.068 12.5 0.0 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain GST_N PF02798.20 EPE33962.1 - 1.2e-18 67.2 0.0 2e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPE33962.1 - 2e-15 56.9 0.0 3.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPE33962.1 - 1.6e-13 50.7 0.0 3e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EPE33962.1 - 7.2e-07 29.3 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPE33962.1 - 2.6e-06 27.4 0.1 6e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPE33962.1 - 0.017 15.3 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EPE33962.1 - 0.052 13.8 0.0 0.091 13.1 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EPE33962.1 - 0.068 13.0 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EPE33962.1 - 0.12 13.1 0.0 0.22 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Jnk-SapK_ap_N PF09744.9 EPE33963.1 - 0.00064 20.0 5.4 0.00074 19.8 5.4 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Uso1_p115_C PF04871.13 EPE33963.1 - 0.001 19.5 3.9 0.0013 19.1 3.9 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region BRE1 PF08647.11 EPE33963.1 - 0.0013 18.7 6.2 0.0017 18.4 6.2 1.1 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase HAP1_N PF04849.13 EPE33963.1 - 0.0015 17.8 6.5 0.002 17.4 6.5 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region ATG16 PF08614.11 EPE33963.1 - 0.0022 18.3 4.4 0.0029 17.9 4.4 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Phage_GPO PF05929.11 EPE33963.1 - 0.0027 17.4 1.3 0.0031 17.2 1.3 1.0 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase bZIP_1 PF00170.21 EPE33963.1 - 0.0052 16.9 2.5 0.0052 16.9 2.5 1.6 2 0 0 2 2 1 1 bZIP transcription factor Golgin_A5 PF09787.9 EPE33963.1 - 0.0053 16.3 4.3 0.0065 16.0 4.3 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 COG5 PF10392.9 EPE33963.1 - 0.0066 16.6 3.3 0.0084 16.3 3.3 1.1 1 0 0 1 1 1 1 Golgi transport complex subunit 5 TSC22 PF01166.18 EPE33963.1 - 0.0072 16.6 2.9 0.0072 16.6 2.9 1.7 1 1 0 1 1 1 1 TSC-22/dip/bun family DUF3958 PF13125.6 EPE33963.1 - 0.0074 16.5 3.2 0.011 15.9 3.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3958) DUF3450 PF11932.8 EPE33963.1 - 0.0093 15.3 4.1 0.012 14.9 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) HD_2 PF12917.7 EPE33963.1 - 0.015 15.1 0.6 0.017 14.9 0.6 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme YabA PF06156.13 EPE33963.1 - 0.016 15.8 4.9 0.027 15.1 4.6 1.5 1 1 0 1 1 1 0 Initiation control protein YabA Med9 PF07544.13 EPE33963.1 - 0.022 14.8 3.1 0.049 13.7 3.1 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF922 PF06037.11 EPE33963.1 - 0.032 14.0 0.7 0.038 13.8 0.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) LXG PF04740.12 EPE33963.1 - 0.044 13.5 4.3 0.059 13.1 4.3 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Prominin PF05478.11 EPE33963.1 - 0.045 11.7 2.1 0.053 11.5 2.1 1.1 1 0 0 1 1 1 0 Prominin MctB PF11382.8 EPE33963.1 - 0.061 13.0 0.4 0.088 12.5 0.4 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB KI67R PF08065.12 EPE33963.1 - 0.073 13.6 1.9 0.095 13.2 1.9 1.1 1 0 0 1 1 1 0 KI67R (NUC007) repeat DUF724 PF05266.14 EPE33963.1 - 0.082 12.7 4.6 0.11 12.3 4.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) TPR_MLP1_2 PF07926.12 EPE33963.1 - 0.087 12.9 9.2 0.11 12.5 9.2 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PhageMin_Tail PF10145.9 EPE33963.1 - 0.14 12.0 1.3 1.5 8.6 0.2 2.0 1 1 1 2 2 2 0 Phage-related minor tail protein Vps51 PF08700.11 EPE33963.1 - 0.15 12.1 4.4 0.25 11.4 4.4 1.5 1 0 0 1 1 1 0 Vps51/Vps67 DUF1664 PF07889.12 EPE33963.1 - 0.16 12.0 4.0 0.21 11.6 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Cluap1 PF10234.9 EPE33963.1 - 0.23 10.8 5.7 0.3 10.5 5.7 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Snf7 PF03357.21 EPE33963.1 - 0.28 10.8 7.6 0.099 12.2 4.1 2.0 2 1 1 3 3 3 0 Snf7 Prefoldin_2 PF01920.20 EPE33963.1 - 0.32 10.9 8.3 0.084 12.8 3.0 2.0 1 1 1 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.8 EPE33963.1 - 0.53 10.3 9.2 1.1 9.3 9.2 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 EPE33963.1 - 0.72 10.3 8.8 0.38 11.2 6.5 1.8 1 1 1 2 2 2 0 Cell division protein ZapB M PF02370.16 EPE33963.1 - 1.1 10.0 6.6 0.21 12.2 2.6 2.1 2 0 0 2 2 1 0 M protein repeat DivIC PF04977.15 EPE33963.1 - 1.5 8.6 5.9 0.9 9.4 4.0 1.7 1 1 0 1 1 1 0 Septum formation initiator Sas10 PF09368.10 EPE33964.1 - 0.16 12.5 1.8 0.17 12.4 1.0 1.4 1 1 0 1 1 1 0 Sas10 C-terminal domain DNA_ligase_OB PF03120.16 EPE33965.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain NPV_P10 PF05531.12 EPE33967.1 - 0.0046 17.4 0.1 0.0081 16.6 0.1 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein YabA PF06156.13 EPE33967.1 - 0.0069 17.0 1.5 0.011 16.4 1.5 1.3 1 1 0 1 1 1 1 Initiation control protein YabA MCC-bdg_PDZ PF10506.9 EPE33967.1 - 0.023 14.7 0.7 0.041 13.9 0.7 1.5 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Spc29 PF17082.5 EPE33967.1 - 0.034 14.0 3.5 0.06 13.2 3.5 1.4 1 1 0 1 1 1 0 Spindle Pole Component 29 DivIC PF04977.15 EPE33967.1 - 0.036 13.9 0.1 0.036 13.9 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator FlxA PF14282.6 EPE33967.1 - 0.039 13.9 6.4 0.39 10.7 6.4 2.0 1 1 0 1 1 1 0 FlxA-like protein RFC1 PF08519.12 EPE33967.1 - 0.046 13.9 0.3 0.056 13.6 0.3 1.2 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain APC_N_CC PF16689.5 EPE33967.1 - 0.047 13.8 1.3 0.08 13.0 1.3 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain KLRAQ PF10205.9 EPE33967.1 - 0.13 12.5 5.7 0.2 11.9 5.7 1.4 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein MIF4G_like_2 PF09090.11 EPE33967.1 - 0.13 11.7 3.6 0.17 11.4 3.6 1.2 1 0 0 1 1 1 0 MIF4G like TMCO5 PF14992.6 EPE33967.1 - 0.27 10.8 6.1 0.35 10.4 6.1 1.2 1 0 0 1 1 1 0 TMCO5 family V_ATPase_I PF01496.19 EPE33967.1 - 0.32 8.9 2.8 0.36 8.7 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 EPE33967.1 - 1.7 7.9 5.8 2.7 7.2 5.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 EPE33967.1 - 3.9 8.0 12.3 30 5.1 12.3 2.1 1 1 0 1 1 1 0 Cell division protein ZapB DUF4200 PF13863.6 EPE33968.1 - 0.026 14.9 0.6 0.029 14.8 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DivIVA PF05103.13 EPE33968.1 - 0.042 13.9 0.6 0.42 10.7 0.0 1.9 1 1 1 2 2 2 0 DivIVA protein Filament PF00038.21 EPE33968.1 - 0.045 13.3 0.1 0.051 13.2 0.1 1.0 1 0 0 1 1 1 0 Intermediate filament protein TFIIB_C_1 PF18542.1 EPE33968.1 - 0.072 13.1 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 Colicin PF01024.19 EPE33968.1 - 0.094 12.6 0.2 0.14 12.1 0.2 1.3 1 1 0 1 1 1 0 Colicin pore forming domain RSN1_7TM PF02714.15 EPE33969.1 - 1.9e-86 289.8 25.4 1.9e-86 289.8 25.4 2.6 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EPE33969.1 - 1.8e-45 154.5 0.3 1.8e-45 154.5 0.3 3.0 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EPE33969.1 - 3.7e-29 102.2 1.9 1.6e-15 57.8 0.2 2.6 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EPE33969.1 - 4.1e-15 55.7 0.0 1.1e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter NARP1 PF12569.8 EPE33969.1 - 3.1 6.6 9.7 6.5 5.5 9.7 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Abhydrolase_6 PF12697.7 EPE33970.1 - 2.7e-11 44.5 0.0 6.2e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE33970.1 - 4e-09 36.5 0.0 1.1e-08 35.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 EPE33970.1 - 6.3e-05 21.8 0.0 9.8e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 EPE33970.1 - 0.0012 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative esterase EthD PF07110.11 EPE33970.1 - 0.0015 19.6 0.6 2.4 9.4 0.2 3.3 2 2 0 2 2 2 2 EthD domain Hydrolase_4 PF12146.8 EPE33970.1 - 0.002 17.5 0.0 0.0063 15.8 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Lactonase PF10282.9 EPE33971.1 - 2.3e-16 60.0 0.0 3.8e-16 59.3 0.0 1.3 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Dioxygenase_C PF00775.21 EPE33972.1 - 1.5e-46 158.2 0.0 2e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EPE33972.1 - 6.9e-24 83.5 0.1 1.1e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus SpaA PF17802.1 EPE33972.1 - 0.00035 20.8 0.0 0.00061 20.1 0.0 1.4 1 0 0 1 1 1 1 Prealbumin-like fold domain CarboxypepD_reg PF13620.6 EPE33972.1 - 0.011 16.0 0.0 0.11 12.8 0.1 2.5 2 1 0 2 2 2 0 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 EPE33972.1 - 0.024 14.9 0.1 0.11 12.7 0.0 1.9 1 1 1 2 2 2 0 SdrD B-like domain Abhydrolase_3 PF07859.13 EPE33973.1 - 2.6e-44 151.6 0.0 3.4e-32 112.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE33973.1 - 2.3e-05 25.1 0.9 3.8e-05 24.4 0.9 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 EPE33973.1 - 0.0009 18.2 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Sugar_tr PF00083.24 EPE33974.1 - 2e-90 303.9 19.9 2.3e-90 303.6 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE33974.1 - 4e-24 85.2 27.3 1.9e-23 83.0 22.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPE33974.1 - 7.4e-07 28.0 2.9 7.4e-07 28.0 2.9 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NADH_dehy_S2_C PF06444.11 EPE33974.1 - 0.075 13.6 0.0 0.28 11.7 0.0 2.0 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus MFS_1_like PF12832.7 EPE33974.1 - 2.2 7.0 16.9 0.051 12.4 6.3 2.2 2 0 0 2 2 2 0 MFS_1 like family HeLo PF14479.6 EPE33975.1 - 3e-48 164.4 0.1 4.9e-48 163.7 0.1 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation AAA PF00004.29 EPE33975.1 - 4.3e-07 30.4 0.0 1.1e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EPE33975.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 EPE33975.1 - 0.013 15.6 0.0 0.036 14.1 0.0 1.7 1 0 0 1 1 1 0 Torsin Pet100 PF09803.9 EPE33975.1 - 0.019 15.5 0.1 0.43 11.1 0.0 2.8 2 0 0 2 2 2 0 Pet100 Mg_chelatase PF01078.21 EPE33975.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EPE33975.1 - 0.061 13.7 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Latarcin PF10279.9 EPE33975.1 - 1.3 9.5 3.3 1.8 9.0 0.4 2.7 3 0 0 3 3 3 0 Latarcin precursor F-box-like PF12937.7 EPE33976.1 - 1.7e-09 37.4 0.2 5.6e-09 35.8 0.2 2.0 1 0 0 1 1 1 1 F-box-like Amidoligase_2 PF12224.8 EPE33977.1 - 0.064 12.9 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme FMO-like PF00743.19 EPE33979.1 - 2.4e-17 62.6 0.1 3.3e-14 52.2 0.1 2.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EPE33979.1 - 9.1e-12 44.8 0.0 2.7e-09 36.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE33979.1 - 8.1e-11 41.7 0.2 3e-10 39.8 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE33979.1 - 2.7e-10 40.3 0.1 1.1e-08 35.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EPE33979.1 - 7.3e-08 31.9 0.0 9.9e-07 28.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 EPE33979.1 - 7.2e-07 28.7 0.0 0.0001 21.6 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EPE33979.1 - 3.4e-05 23.6 2.9 0.0021 17.7 0.5 3.6 3 2 2 5 5 5 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EPE33979.1 - 5e-05 23.8 0.2 0.37 11.4 0.0 3.4 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EPE33979.1 - 0.0051 16.2 2.5 0.011 15.1 0.2 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EPE33979.1 - 0.007 15.5 0.5 0.096 11.7 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein GIDA PF01134.22 EPE33979.1 - 0.0079 15.3 0.6 0.53 9.3 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EPE33979.1 - 0.018 13.9 0.2 2.7 6.8 0.2 2.3 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.24 EPE33979.1 - 0.021 13.9 1.2 0.022 13.9 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.6 EPE33979.1 - 0.099 13.1 0.0 0.49 10.9 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 EPE33979.1 - 0.14 12.2 0.0 2.7 8.1 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 EPE33979.1 - 0.26 9.9 0.9 0.75 8.4 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein SET PF00856.28 EPE33980.1 - 4.4e-15 56.5 3.5 7.8e-14 52.4 0.1 3.5 4 0 0 4 4 4 1 SET domain Ezh2_MCSS PF18600.1 EPE33980.1 - 0.00017 21.1 0.7 0.00039 20.0 0.7 1.5 1 0 0 1 1 1 1 MCSS domain EZH2_N PF18601.1 EPE33980.1 - 0.0045 17.3 0.0 0.027 14.8 0.0 2.3 2 0 0 2 2 2 1 EZH2 N-terminal domain preSET_CXC PF18264.1 EPE33980.1 - 0.0057 17.1 16.6 0.0057 17.1 16.6 3.0 2 1 0 2 2 2 1 CXC domain PBP1_TM PF14812.6 EPE33980.1 - 1.3 9.4 8.1 21 5.6 3.4 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pil1 PF13805.6 EPE33982.1 - 1e-128 428.4 0.2 1.3e-128 428.1 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 EPE33982.1 - 0.079 12.4 2.5 0.094 12.1 1.1 1.8 1 1 1 2 2 2 0 FAM92 protein Atg14 PF10186.9 EPE33982.1 - 0.57 9.2 3.7 7.4 5.6 0.4 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BRAP2 PF07576.12 EPE33983.1 - 4.3e-31 107.1 0.0 6.7e-31 106.5 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EPE33983.1 - 8e-16 58.1 7.0 2.3e-15 56.7 7.0 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EPE33983.1 - 2.2e-08 34.3 9.0 2.2e-08 34.3 9.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPE33983.1 - 1.4e-06 28.1 9.5 3.4e-06 26.8 9.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE33983.1 - 0.00019 21.2 8.0 0.00047 20.0 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE33983.1 - 0.00036 20.5 3.7 0.00036 20.5 3.7 2.5 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EPE33983.1 - 0.00042 20.0 4.6 0.00042 20.0 4.6 2.4 2 0 0 2 2 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EPE33983.1 - 0.00073 19.8 6.4 0.00073 19.8 6.4 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EPE33983.1 - 0.0018 18.1 7.0 0.0018 18.1 7.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE33983.1 - 0.002 18.1 8.4 0.002 18.1 8.4 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_6 PF14835.6 EPE33983.1 - 0.0057 16.5 2.5 0.02 14.7 2.5 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EPE33983.1 - 0.016 15.2 6.1 0.016 15.2 6.1 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2353 PF09789.9 EPE33983.1 - 0.042 13.2 3.1 0.065 12.6 3.1 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Rootletin PF15035.6 EPE33983.1 - 0.69 9.9 5.8 1.3 9.1 5.8 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.9 EPE33983.1 - 0.87 8.6 3.4 1.8 7.6 3.4 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-RING_4 PF14570.6 EPE33983.1 - 1.1 9.1 6.1 3.4 7.5 6.1 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EPE33983.1 - 1.5 8.7 20.6 0.21 11.5 11.2 3.1 2 1 1 3 3 2 0 Prokaryotic RING finger family 4 Spc7 PF08317.11 EPE33983.1 - 1.5 7.6 8.2 2.3 7.0 8.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Rho_Binding PF08912.11 EPE33983.1 - 4.5 8.2 6.8 5.7 7.8 5.0 2.1 2 0 0 2 2 1 0 Rho Binding DUF4349 PF14257.6 EPE33983.1 - 7.4 6.0 7.9 3.7 6.9 5.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) ubiquitin PF00240.23 EPE33984.1 - 4.4e-135 439.7 20.4 3.3e-33 113.3 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 EPE33984.1 - 6.6e-64 211.7 21.0 2e-15 56.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EPE33984.1 - 8.1e-23 80.7 10.7 0.00043 20.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 EPE33984.1 - 1.7e-16 59.9 3.0 0.027 14.4 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EPE33984.1 - 3.9e-15 56.0 8.2 0.028 14.8 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EPE33984.1 - 2.1e-14 53.6 2.6 0.12 12.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EPE33984.1 - 5.6e-13 49.4 1.4 0.37 11.4 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EPE33984.1 - 5.2e-11 42.7 0.8 0.52 10.1 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EPE33984.1 - 3.7e-07 30.1 24.0 16 5.6 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 EPE33984.1 - 2.9e-06 26.8 0.4 1.8 7.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 EPE33984.1 - 3.8e-06 27.0 2.5 13 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 EPE33984.1 - 7.1e-06 26.3 0.0 30 5.1 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 EPE33984.1 - 1.2e-05 25.0 4.7 10 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain Big_7 PF17957.1 EPE33984.1 - 4e-05 24.3 0.1 52 4.7 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 EPE33984.1 - 0.00014 21.9 4.3 7.1 6.8 0.0 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EPE33984.1 - 0.00042 19.8 0.0 23 4.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) YcgR_2 PF12945.7 EPE33984.1 - 0.00091 19.3 6.2 29 4.9 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 EPE33984.1 - 0.003 18.1 0.1 1.4e+02 3.1 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 EPE33984.1 - 0.0037 16.9 0.0 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 EPE33984.1 - 0.0052 17.4 1.0 1.4e+02 3.1 0.0 4.2 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 EPE33984.1 - 0.0068 16.5 0.0 91 3.3 0.0 4.3 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 EPE33984.1 - 0.11 12.7 5.8 1.1e+02 3.1 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Baculo_p48 PF04878.13 EPE33984.1 - 0.12 11.2 0.0 61 2.4 0.0 3.0 3 0 0 3 3 3 0 Baculovirus P48 protein Tash_PEST PF07708.11 EPE33984.1 - 0.14 12.4 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif Myosin_N PF02736.19 EPE33984.1 - 0.23 11.3 6.3 1.1e+02 2.8 0.0 5.2 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain HAMP_N3 PF18575.1 EPE33984.1 - 0.23 11.0 1.5 2e+02 1.6 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 PI3K_p85B PF02192.16 EPE33984.1 - 1.9 8.3 9.3 96 2.8 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain Zn_clus PF00172.18 EPE33985.1 - 0.0048 17.0 7.8 0.0099 16.0 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIRM-assoc_2 PF16496.5 EPE33987.1 - 0.00063 18.7 0.1 0.00063 18.7 0.1 3.6 4 0 0 4 4 4 1 SWIRM-associated domain at the N-terminal AT_hook PF02178.19 EPE33987.1 - 0.0024 17.5 0.6 3.3 7.9 0.0 3.8 2 0 0 2 2 2 2 AT hook motif PTCB-BRCT PF12738.7 EPE33987.1 - 0.013 15.5 0.3 0.091 12.7 0.3 2.2 1 1 0 1 1 1 0 twin BRCT domain Acyltransferase PF01553.21 EPE33989.1 - 2e-10 40.4 0.0 2.5e-09 36.8 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase adh_short PF00106.25 EPE33990.1 - 0.00033 20.2 0.2 1.5 8.2 0.0 3.2 4 0 0 4 4 4 2 short chain dehydrogenase GrpB PF04229.14 EPE33993.1 - 6.9e-33 114.1 0.0 8e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 GrpB protein NTP_transf_5 PF14907.6 EPE33993.1 - 0.0085 15.7 0.0 0.014 15.1 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised nucleotidyltransferase Transp_cyt_pur PF02133.15 EPE33994.1 - 2.1e-100 336.5 40.4 2.5e-100 336.3 40.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RPN2_C PF18004.1 EPE33995.1 - 1.4e-57 194.1 10.1 2.3e-57 193.4 10.1 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EPE33995.1 - 4.5e-41 137.3 21.7 2.1e-09 37.3 0.0 8.9 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EPE33995.1 - 8.7e-22 77.3 0.1 5.4e-15 55.6 0.0 5.9 4 1 2 6 6 6 2 HEAT repeats HEAT PF02985.22 EPE33995.1 - 1.4e-06 28.1 0.6 7 7.2 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.6 EPE33995.1 - 6.4e-06 26.6 0.0 0.0068 16.9 0.0 4.9 2 1 1 3 3 3 2 HEAT-like repeat Phage_TAC_12 PF12363.8 EPE33995.1 - 0.00043 20.7 0.6 0.61 10.5 0.1 3.6 3 0 0 3 3 3 2 Phage tail assembly chaperone protein, TAC Cnd1 PF12717.7 EPE33995.1 - 0.0027 17.8 0.1 1.7 8.7 0.0 3.7 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 EPE33995.1 - 0.0067 16.9 1.6 15 6.2 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE33995.1 - 0.037 14.2 0.7 1.9 8.8 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 HEAT_PBS PF03130.16 EPE33995.1 - 0.039 14.6 0.2 4.4 8.3 0.0 4.3 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat mRNA_triPase PF02940.15 EPE33996.1 - 1.2e-55 188.6 0.0 1.8e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Sugar_tr PF00083.24 EPE33997.1 - 1.4e-95 320.9 17.0 1.6e-95 320.7 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE33997.1 - 8.9e-41 140.0 28.0 2.8e-33 115.3 14.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 EPE33997.1 - 0.00015 20.9 3.1 0.0013 17.7 0.5 2.2 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM TRI12 PF06609.13 EPE33997.1 - 0.00051 18.6 4.3 0.012 14.1 0.6 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_2_C PF02836.17 EPE33998.1 - 6.3e-104 347.3 0.0 8.4e-104 346.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 EPE33998.1 - 1.5e-64 217.9 0.0 3e-64 217.0 0.0 1.5 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 EPE33998.1 - 1.1e-30 106.7 0.0 3.1e-30 105.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 EPE33998.1 - 3.8e-22 78.6 0.2 8.8e-21 74.2 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 EPE33998.1 - 4.5e-14 53.0 0.0 1.2e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Cellulase PF00150.18 EPE33999.1 - 1.4e-15 57.5 5.3 1.4e-15 57.5 5.3 1.9 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Acyl-CoA_dh_1 PF00441.24 EPE34000.1 - 3.5e-35 121.4 1.9 4.1e-35 121.2 1.0 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EPE34000.1 - 1.9e-19 69.6 0.1 6e-19 68.1 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EPE34000.1 - 1.7e-11 44.5 0.1 3e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EPE34000.1 - 2.2e-06 28.3 0.0 2.9e-05 24.7 0.0 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 EPE34000.1 - 0.0031 17.2 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Glyco_hydro_76 PF03663.14 EPE34002.1 - 8e-155 515.9 15.8 9.4e-155 515.6 15.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EPE34002.1 - 0.16 11.0 11.8 0.83 8.7 1.1 3.0 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 FAD_binding_3 PF01494.19 EPE34003.1 - 1.4e-13 50.8 0.1 6.9e-13 48.6 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE34003.1 - 7.8e-05 22.0 0.1 0.042 13.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPE34003.1 - 0.00021 21.3 0.0 0.58 10.1 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 EPE34003.1 - 0.00031 20.4 1.0 0.0065 16.1 0.0 2.5 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE34003.1 - 0.00046 20.4 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPE34003.1 - 0.00053 19.2 0.0 0.053 12.6 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.24 EPE34003.1 - 0.0027 17.0 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SE PF08491.10 EPE34003.1 - 0.011 14.8 0.0 0.1 11.6 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Thi4 PF01946.17 EPE34003.1 - 0.025 13.8 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Mqo PF06039.15 EPE34003.1 - 0.025 13.2 0.3 0.046 12.3 0.0 1.5 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Trp_halogenase PF04820.14 EPE34003.1 - 0.15 10.9 0.2 3.4 6.4 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase ADH_N PF08240.12 EPE34004.1 - 5.5e-21 74.5 2.0 9.6e-21 73.7 2.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE34004.1 - 5.6e-09 36.1 0.1 1.6e-06 28.1 0.0 3.6 2 1 1 3 3 3 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EPE34004.1 - 0.0002 20.8 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EPE34004.1 - 0.013 14.8 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MRP-L51 PF10244.9 EPE34004.1 - 0.19 12.0 0.0 0.49 10.7 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit F-box-like PF12937.7 EPE34005.1 - 0.046 13.6 0.3 0.091 12.7 0.3 1.5 1 0 0 1 1 1 0 F-box-like NOA36 PF06524.12 EPE34005.1 - 2.9 7.2 10.9 4.4 6.5 10.9 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 EPE34005.1 - 3.8 7.7 14.6 13 5.9 14.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 BsuBI_PstI_RE PF06616.11 EPE34006.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain SesA PF17107.5 EPE34009.1 - 9.1e-07 29.1 2.4 5.6e-06 26.5 2.4 2.4 1 1 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 EPE34009.1 - 9.7e-07 28.8 0.0 3.9e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EPE34009.1 - 2.7e-05 24.5 0.0 9.8e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EPE34009.1 - 0.0013 19.3 0.0 0.006 17.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPE34009.1 - 0.0026 18.2 0.0 0.012 16.0 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EPE34009.1 - 0.0075 16.8 0.1 0.026 15.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.6 EPE34009.1 - 0.0092 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EPE34009.1 - 0.013 15.3 0.3 0.032 14.0 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EPE34009.1 - 0.019 15.4 0.1 0.043 14.2 0.1 1.6 1 0 0 1 1 1 0 RNA helicase Ploopntkinase3 PF18751.1 EPE34009.1 - 0.021 14.7 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Viral_helicase1 PF01443.18 EPE34009.1 - 0.051 13.3 0.0 0.55 9.9 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF3196 PF11428.8 EPE34009.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) MMR_HSR1 PF01926.23 EPE34009.1 - 0.082 13.0 0.1 0.26 11.4 0.0 1.8 2 0 0 2 2 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EPE34009.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EPE34009.1 - 0.13 12.0 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EPE34009.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EPE34009.1 - 0.15 12.5 3.3 2 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EPE34009.1 - 0.18 11.4 1.1 0.23 11.1 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ALIX_LYPXL_bnd PF13949.6 EPE34010.1 - 9.6e-05 21.8 1.7 0.00019 20.8 1.7 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Glyco_hydro_106 PF17132.4 EPE34011.1 - 2.9e-08 32.5 0.1 8.1e-07 27.7 0.1 2.7 2 1 0 2 2 2 2 alpha-L-rhamnosidase Glyco_hydro_42M PF08532.10 EPE34011.1 - 0.036 13.6 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain 3Beta_HSD PF01073.19 EPE34012.1 - 2.1e-40 138.5 0.0 2.9e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPE34012.1 - 6.6e-25 88.0 0.0 9.3e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Hemerythrin PF01814.23 EPE34012.1 - 4.2e-12 46.8 1.5 7e-12 46.1 1.5 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain RmlD_sub_bind PF04321.17 EPE34012.1 - 1.7e-11 43.8 0.0 2.5e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EPE34012.1 - 6.8e-10 38.9 0.3 1.4e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPE34012.1 - 1e-08 34.7 0.0 2.3e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EPE34012.1 - 1.4e-05 25.0 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EPE34012.1 - 0.00017 21.5 0.0 0.0015 18.4 0.0 2.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE34012.1 - 0.0002 20.6 0.5 0.00057 19.1 0.5 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 EPE34012.1 - 0.0042 17.2 0.0 0.015 15.4 0.0 2.0 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus AstE_AspA PF04952.14 EPE34012.1 - 0.051 12.7 0.1 0.1 11.7 0.1 1.5 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family NAD_binding_3 PF03447.16 EPE34012.1 - 0.059 14.0 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain TadE PF07811.12 EPE34013.1 - 0.027 14.8 0.9 0.054 13.8 0.9 1.6 1 1 0 1 1 1 0 TadE-like protein Tad PF13400.6 EPE34013.1 - 0.057 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like LptF_LptG PF03739.14 EPE34013.1 - 0.12 11.2 1.2 0.14 11.0 1.2 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF1275 PF06912.11 EPE34013.1 - 0.2 11.5 0.2 0.24 11.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) DUF648 PF04890.13 EPE34013.1 - 0.49 10.1 1.9 0.52 10.0 1.9 1.2 1 1 0 1 1 1 0 Family of unknown function (DUF648) p450 PF00067.22 EPE34014.1 - 7.7e-51 173.3 0.0 5.5e-36 124.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Yip1 PF04893.17 EPE34015.1 - 1.7e-07 31.1 13.3 4.1e-07 29.9 13.4 1.6 1 1 0 1 1 1 1 Yip1 domain Pex24p PF06398.11 EPE34016.1 - 3.4e-96 322.4 0.1 4.2e-96 322.1 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ribosomal_S9 PF00380.19 EPE34018.1 - 1.4e-39 135.4 0.5 2e-39 134.8 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF-hand_1 PF00036.32 EPE34020.1 - 4.7e-27 91.5 12.0 3.7e-07 29.2 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EPE34020.1 - 2e-24 85.8 11.3 4.6e-14 52.6 1.4 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EPE34020.1 - 9.8e-21 71.9 5.4 4.6e-05 23.0 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EPE34020.1 - 1e-18 65.9 9.8 1.5e-06 27.4 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EPE34020.1 - 9.7e-14 51.0 9.6 0.00014 21.7 0.4 4.3 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EPE34020.1 - 1e-06 29.0 0.0 0.0036 17.6 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EPE34020.1 - 1.4e-06 28.1 7.3 0.0034 17.3 0.4 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EPE34020.1 - 0.032 14.4 0.7 0.13 12.5 0.7 2.1 1 1 0 1 1 1 0 Dockerin type I domain EPL1 PF10513.9 EPE34021.1 - 1.7e-21 77.2 3.6 1.7e-21 77.2 3.6 2.4 2 1 0 2 2 2 1 Enhancer of polycomb-like SET PF00856.28 EPE34022.1 - 3.2e-20 73.2 0.2 2.8e-19 70.1 0.0 2.1 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EPE34022.1 - 1.2e-15 58.4 4.0 2.4e-15 57.4 4.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding PHD PF00628.29 EPE34023.1 - 3.4e-16 58.9 19.3 1.5e-10 40.8 9.5 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 EPE34023.1 - 0.016 14.7 14.6 0.032 13.8 4.5 3.4 3 0 0 3 3 3 0 PHD-finger zf-HC5HC2H PF13771.6 EPE34023.1 - 0.14 12.4 9.9 0.069 13.4 3.4 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-PHD-like PF15446.6 EPE34023.1 - 6.5 6.3 17.9 0.65 9.6 3.0 3.1 3 1 1 4 4 4 0 PHD/FYVE-zinc-finger like domain Peptidase_M22 PF00814.25 EPE34024.1 - 1.7e-83 280.5 0.0 2.1e-83 280.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EPE34024.1 - 0.03 14.0 0.0 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus LapA_dom PF06305.11 EPE34025.1 - 0.084 12.7 0.2 0.084 12.7 0.2 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Wzy_C PF04932.15 EPE34025.1 - 0.78 9.4 5.0 1.1 8.8 5.0 1.3 1 1 0 1 1 1 0 O-Antigen ligase AMPKBI PF04739.15 EPE34026.1 - 4.4e-26 91.0 2.4 4.4e-26 91.0 2.4 2.9 4 0 0 4 4 4 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 EPE34026.1 - 2.5e-24 85.3 0.0 4.6e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase p450 PF00067.22 EPE34027.1 - 2.6e-24 85.8 0.0 1e-18 67.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Ham1p_like PF01725.16 EPE34028.1 - 2.7e-59 200.3 0.0 3e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.6 EPE34029.1 - 1.2e-27 97.0 1.8 1.2e-27 97.0 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EPE34029.1 - 1.3e-10 41.8 0.1 1.5e-09 38.4 0.0 2.2 1 1 1 2 2 2 1 AAA domain ADK PF00406.22 EPE34029.1 - 1.4e-06 28.5 0.0 0.00018 21.6 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.6 EPE34029.1 - 6.4e-05 23.1 0.1 0.0037 17.4 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA PF00004.29 EPE34029.1 - 0.00014 22.3 0.0 0.00038 20.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 EPE34029.1 - 0.00015 21.7 3.1 0.095 12.5 0.2 2.1 1 1 0 2 2 2 2 Deoxynucleoside kinase AAA_28 PF13521.6 EPE34029.1 - 0.00022 21.5 1.2 0.00042 20.6 1.2 1.8 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EPE34029.1 - 0.00043 20.2 0.1 0.00098 19.1 0.0 1.7 2 0 0 2 2 2 1 NTPase SKI PF01202.22 EPE34029.1 - 0.00051 20.2 0.6 0.0032 17.6 0.6 1.9 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.6 EPE34029.1 - 0.00082 19.7 0.1 0.0023 18.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 EPE34029.1 - 0.0023 18.2 0.0 0.0046 17.2 0.0 1.5 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain Thymidylate_kin PF02223.17 EPE34029.1 - 0.0032 17.2 0.3 1 9.0 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Rad17 PF03215.15 EPE34029.1 - 0.0092 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EPE34029.1 - 0.013 15.9 0.1 0.02 15.3 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 EPE34029.1 - 0.02 14.4 0.1 0.043 13.3 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RuvB_N PF05496.12 EPE34029.1 - 0.028 14.1 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin2 PF13189.6 EPE34029.1 - 0.035 14.2 0.0 0.087 12.9 0.0 1.9 1 1 0 1 1 1 0 Cytidylate kinase-like family RNA_helicase PF00910.22 EPE34029.1 - 0.054 13.9 0.0 0.094 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EPE34029.1 - 0.057 13.5 0.1 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arnt_C PF18583.1 EPE34029.1 - 0.064 12.9 1.5 4.2 7.0 0.2 2.5 3 0 0 3 3 3 0 Aminoarabinose transferase C-terminal domain AAA_24 PF13479.6 EPE34029.1 - 0.065 13.0 1.4 0.083 12.6 0.2 1.9 2 2 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EPE34029.1 - 0.075 13.4 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EPE34029.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 EPE34029.1 - 0.092 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 EPE34029.1 - 0.16 11.7 0.6 0.27 11.0 0.1 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 EPE34029.1 - 0.16 10.9 0.1 0.3 10.0 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 EPE34029.1 - 0.18 11.4 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EPE34029.1 - 0.2 11.3 2.9 1.6 8.4 0.4 2.6 2 1 1 3 3 3 0 AAA domain Myosin_head PF00063.21 EPE34030.1 - 1.6e-259 862.7 0.5 2.8e-259 861.9 0.5 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 EPE34030.1 - 3.2e-26 91.6 2.6 3.2e-26 91.6 2.6 2.9 3 0 0 3 3 2 1 DIL domain IQ PF00612.27 EPE34030.1 - 3.3e-09 35.7 45.4 8.5e-05 22.0 2.1 6.6 6 0 0 6 6 6 3 IQ calmodulin-binding motif Spc7 PF08317.11 EPE34030.1 - 0.00013 21.0 19.3 0.0003 19.8 19.3 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_16 PF13191.6 EPE34030.1 - 0.0044 17.4 1.4 0.023 15.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain KASH_CCD PF14662.6 EPE34030.1 - 0.0053 16.6 7.0 0.0053 16.6 7.0 2.8 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH Myosin_N PF02736.19 EPE34030.1 - 0.0067 16.2 0.5 0.0067 16.2 0.5 1.9 2 0 0 2 2 1 1 Myosin N-terminal SH3-like domain CALCOCO1 PF07888.11 EPE34030.1 - 0.03 13.2 22.6 0.064 12.1 22.6 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF812 PF05667.11 EPE34030.1 - 0.031 13.2 25.8 0.051 12.4 25.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GAS PF13851.6 EPE34030.1 - 0.06 12.7 30.7 0.007 15.7 11.7 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HSF_DNA-bind PF00447.17 EPE34030.1 - 0.068 13.8 0.6 0.35 11.5 0.6 2.3 1 0 0 1 1 1 0 HSF-type DNA-binding APG6_N PF17675.1 EPE34030.1 - 0.068 13.7 33.0 0.061 13.9 26.4 3.0 1 1 1 2 2 2 0 Apg6 coiled-coil region AAA_22 PF13401.6 EPE34030.1 - 0.079 13.2 0.0 0.079 13.2 0.0 2.6 3 0 0 3 3 1 0 AAA domain DegQ PF08181.11 EPE34030.1 - 0.081 13.0 0.9 0.4 10.8 0.9 2.2 1 0 0 1 1 1 0 DegQ (SacQ) family ERM PF00769.19 EPE34030.1 - 0.5 10.2 29.0 0.024 14.5 22.7 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Sec34 PF04136.15 EPE34030.1 - 0.71 9.8 11.3 0.053 13.4 3.4 2.7 1 1 1 2 2 2 0 Sec34-like family zf-C4H2 PF10146.9 EPE34030.1 - 0.76 10.1 12.1 0.18 12.1 8.0 2.1 2 0 0 2 2 1 0 Zinc finger-containing protein TolA_bind_tri PF16331.5 EPE34030.1 - 0.8 9.8 18.8 2.5 8.2 1.7 4.2 2 1 1 3 3 3 0 TolA binding protein trimerisation Snapin_Pallidin PF14712.6 EPE34030.1 - 0.83 10.1 21.2 0.69 10.4 5.8 3.5 2 1 0 2 2 2 0 Snapin/Pallidin Leu_zip PF15294.6 EPE34030.1 - 1.5 8.3 22.5 19 4.7 22.5 2.5 1 1 0 1 1 1 0 Leucine zipper ATG16 PF08614.11 EPE34030.1 - 3.2 7.9 31.7 0.72 10.0 15.5 2.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DHR10 PF18595.1 EPE34030.1 - 3.6 7.7 31.5 5.9 7.0 5.6 3.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain EMP24_GP25L PF01105.24 EPE34030.1 - 3.7 7.4 13.0 0.59 10.1 3.5 2.8 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD FlaC_arch PF05377.11 EPE34030.1 - 5.4 7.5 17.1 0.098 13.1 0.6 4.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) ING PF12998.7 EPE34030.1 - 9.4 6.9 13.5 15 6.2 1.3 3.1 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding 2-Hacid_dh_C PF02826.19 EPE34031.1 - 1.7e-49 167.6 0.0 2.7e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPE34031.1 - 7.1e-35 119.6 0.0 9.4e-35 119.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EPE34031.1 - 2.5e-05 24.5 0.2 5.7e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EPE34031.1 - 0.00097 18.7 0.3 0.02 14.5 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ACT PF01842.25 EPE34031.1 - 0.0021 17.8 0.4 0.0074 16.0 0.1 2.0 2 0 0 2 2 2 1 ACT domain AdoHcyase_NAD PF00670.21 EPE34031.1 - 0.0047 17.0 0.4 0.01 15.9 0.1 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Rossmann-like PF10727.9 EPE34031.1 - 0.021 14.7 0.1 0.067 13.0 0.1 1.8 1 1 0 1 1 1 0 Rossmann-like domain 3HCDH_N PF02737.18 EPE34031.1 - 0.049 13.5 0.1 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 EPE34031.1 - 0.066 13.7 0.0 0.23 12.0 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain NAP PF00956.18 EPE34032.1 - 6.2e-101 337.1 8.7 6.2e-101 337.1 8.7 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) RNA_pol_3_Rpc31 PF11705.8 EPE34032.1 - 8.7 6.5 31.5 0.5 10.6 22.0 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 E1-E2_ATPase PF00122.20 EPE34033.1 - 7.6e-27 94.0 0.0 2.1e-26 92.5 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 EPE34033.1 - 2.9e-24 85.6 2.2 7.6e-13 48.7 1.1 2.8 1 1 1 2 2 2 2 P5-type ATPase cation transporter Hydrolase PF00702.26 EPE34033.1 - 1.8e-17 64.3 0.1 5.4e-09 36.7 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPE34033.1 - 0.0019 18.2 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EPE34033.1 - 0.017 14.8 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus CBP_BcsF PF11120.8 EPE34033.1 - 0.02 15.0 0.6 0.062 13.4 0.1 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF Hydrolase_3 PF08282.12 EPE34033.1 - 0.089 12.5 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EPE34033.1 - 0.28 10.9 11.8 3.2 7.4 9.3 2.9 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus CMAS PF02353.20 EPE34034.1 - 5.8e-39 134.0 1.0 8.5e-39 133.5 1.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EPE34034.1 - 4.2e-16 59.4 0.0 7.2e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE34034.1 - 7.8e-16 58.6 0.0 1.3e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE34034.1 - 5e-14 52.4 0.0 7.2e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE34034.1 - 1.7e-12 47.5 0.0 2.9e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE34034.1 - 1.5e-11 44.9 0.0 2.4e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE34034.1 - 6.8e-08 32.1 0.0 1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EPE34034.1 - 2.2e-07 30.6 0.0 4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EPE34034.1 - 0.00019 20.9 0.0 0.00074 19.0 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.19 EPE34034.1 - 0.00034 20.4 0.0 0.00075 19.3 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 EPE34034.1 - 0.0013 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltr_RsmB-F PF01189.17 EPE34034.1 - 0.0021 17.8 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_2 PF00891.18 EPE34034.1 - 0.0027 17.0 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain DUF938 PF06080.12 EPE34034.1 - 0.0031 17.3 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) RrnaAD PF00398.20 EPE34034.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GidB PF02527.15 EPE34034.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G 4HB_MCP_1 PF12729.7 EPE34035.1 - 0.51 9.9 4.5 0.34 10.4 2.3 1.7 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction NADH_B2 PF14813.6 EPE34037.1 - 0.055 13.3 0.1 0.063 13.1 0.1 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.25 EPE34038.1 - 9.6e-65 218.6 0.0 1.1e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE34038.1 - 4.8e-28 98.2 0.0 6.6e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE34038.1 - 0.00014 21.2 0.0 0.00076 18.9 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EPE34038.1 - 0.15 10.9 0.1 0.39 9.6 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Peptidase_C78 PF07910.13 EPE34039.1 - 1.7e-61 207.4 0.0 2.3e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.12 EPE34039.1 - 0.0036 17.5 1.5 0.046 14.0 0.2 2.6 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.18 EPE34039.1 - 0.1 13.3 0.3 1.1 10.1 0.0 2.5 2 0 0 2 2 2 0 TRAF-type zinc finger zf-H2C2_5 PF13909.6 EPE34039.1 - 0.39 10.5 1.4 0.77 9.6 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain tRNA-synt_2b PF00587.25 EPE34040.1 - 5.1e-37 127.6 0.0 7.8e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EPE34040.1 - 1.3e-19 70.4 6.0 1.3e-19 70.4 6.0 1.9 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain DUF5082 PF16888.5 EPE34040.1 - 0.011 16.0 2.9 0.023 15.0 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) NPIP PF06409.11 EPE34040.1 - 0.19 10.8 2.6 0.3 10.1 2.6 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) ST7 PF04184.12 EPE34040.1 - 0.23 9.9 1.3 0.36 9.3 1.3 1.2 1 0 0 1 1 1 0 ST7 protein Ras PF00071.22 EPE34041.1 - 1.4e-46 158.1 0.8 1.6e-46 157.9 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE34041.1 - 3.9e-17 62.6 0.1 5.5e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE34041.1 - 5.7e-08 32.4 0.0 6.2e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EPE34041.1 - 2e-06 27.5 0.4 3e-05 23.7 0.1 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EPE34041.1 - 0.00012 22.1 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EPE34041.1 - 0.00015 21.2 0.0 0.0003 20.3 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EPE34041.1 - 0.00023 21.1 0.6 0.026 14.4 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 EPE34041.1 - 0.02 15.1 0.1 0.1 12.8 0.0 2.1 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.18 EPE34041.1 - 0.064 12.8 0.0 0.22 11.1 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B WAPL PF07814.13 EPE34042.1 - 7.8e-80 268.4 2.5 1.4e-79 267.6 0.5 2.0 1 1 1 2 2 2 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.6 EPE34043.1 - 6.9e-79 264.1 0.0 9.3e-79 263.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EPE34043.1 - 0.0018 17.8 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 EPE34043.1 - 0.1 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) CoA_binding_2 PF13380.6 EPE34043.1 - 0.17 12.4 0.0 0.31 11.6 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain Elf1 PF05129.13 EPE34044.1 - 4.7e-30 103.5 3.5 5.8e-30 103.2 3.5 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like EST1_DNA_bind PF10373.9 EPE34044.1 - 0.025 14.1 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain GTP_CH_N PF12471.8 EPE34045.1 - 5.1e-91 303.7 0.0 7.3e-91 303.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EPE34045.1 - 8.6e-18 64.5 0.0 2.3e-17 63.1 0.0 1.6 2 0 0 2 2 2 1 GTP cyclohydrolase II Ribosomal_S3Ae PF01015.18 EPE34047.1 - 7.1e-90 300.0 3.4 8.6e-90 299.7 3.4 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EPE34047.1 - 0.011 16.3 0.1 0.096 13.2 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 EPE34047.1 - 0.075 13.0 0.3 0.5 10.4 0.0 2.2 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Ras PF00071.22 EPE34048.1 - 2.5e-50 170.2 0.0 2.9e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE34048.1 - 3.4e-27 95.0 0.0 4.4e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE34048.1 - 2.3e-13 50.0 0.0 2.9e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EPE34048.1 - 4.8e-07 29.4 0.0 5.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EPE34048.1 - 1.5e-06 27.9 0.0 3e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EPE34048.1 - 5.6e-05 23.2 0.0 0.00014 21.9 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EPE34048.1 - 0.0024 18.0 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPE34048.1 - 0.0062 16.9 0.0 0.0089 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EPE34048.1 - 0.009 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SRPRB PF09439.10 EPE34048.1 - 0.0094 15.4 0.0 0.013 15.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EPE34048.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EPE34048.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EPE34048.1 - 0.17 11.8 0.0 0.82 9.6 0.0 1.9 2 1 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EPE34048.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EPE34048.1 - 0.18 11.0 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Septin Abhydrolase_1 PF00561.20 EPE34049.1 - 5.1e-27 95.1 0.1 1.3e-20 74.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE34049.1 - 7.9e-16 59.3 0.0 1e-15 58.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE34049.1 - 6.7e-13 48.5 0.3 2.8e-12 46.4 0.2 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EPE34049.1 - 2.1e-07 30.9 0.2 0.00016 21.5 0.2 2.2 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 EPE34049.1 - 1.1e-06 29.0 0.0 1.7e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EPE34049.1 - 0.00031 20.5 0.0 0.0004 20.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Palm_thioest PF02089.15 EPE34049.1 - 0.0077 16.1 0.0 0.011 15.6 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Chlorophyllase2 PF12740.7 EPE34049.1 - 0.019 13.9 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF676 PF05057.14 EPE34049.1 - 0.046 13.2 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ndr PF03096.14 EPE34049.1 - 0.08 11.6 0.0 0.17 10.6 0.0 1.4 2 0 0 2 2 2 0 Ndr family Abhydrolase_2 PF02230.16 EPE34049.1 - 0.091 12.6 0.0 6.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Gly_transf_sug PF04488.15 EPE34050.1 - 2.8e-21 76.0 0.1 5.4e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EPE34050.1 - 0.65 9.2 5.3 0.41 9.9 0.5 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Peptidase_C97 PF05903.14 EPE34051.1 - 0.00016 21.5 0.0 0.0004 20.2 0.0 1.5 1 1 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EPE34051.1 - 0.036 14.4 0.7 0.27 11.6 0.0 2.2 1 1 1 2 2 2 0 Lecithin retinol acyltransferase DUF4105 PF13387.6 EPE34051.1 - 0.081 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Forkhead PF00250.18 EPE34052.1 - 1.2e-33 115.3 0.1 2.2e-33 114.4 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain Mid1 PF12929.7 EPE34054.1 - 3e-137 458.3 0.8 3.5e-137 458.1 0.8 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EPE34054.1 - 2.4e-05 24.9 5.1 0.0051 17.4 3.0 2.6 2 0 0 2 2 2 2 Fz domain TB2_DP1_HVA22 PF03134.19 EPE34055.1 - 3.2e-27 94.2 8.8 5.6e-27 93.5 8.8 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family PSI_PsaE PF02427.17 EPE34055.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IV / PsaE RFX_DNA_binding PF02257.15 EPE34056.1 - 1.5e-27 96.0 0.1 5.2e-27 94.3 0.1 2.0 1 0 0 1 1 1 1 RFX DNA-binding domain Cdc6_C PF09079.11 EPE34056.1 - 0.012 15.5 0.0 0.048 13.6 0.0 2.0 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain AA_kinase PF00696.28 EPE34057.1 - 3.5e-40 138.1 1.0 5.6e-40 137.4 0.1 1.8 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 EPE34057.1 - 1.4e-13 50.3 1.0 6.5e-07 29.0 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 EPE34057.1 - 2.1e-11 43.5 4.4 9.2e-09 35.0 0.3 2.5 2 0 0 2 2 2 2 ACT domain RRM_2 PF04059.12 EPE34058.1 - 4.9e-39 132.4 0.2 8.4e-39 131.7 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EPE34058.1 - 0.0001 22.0 0.1 0.019 14.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec15 PF04091.12 EPE34059.1 - 4e-78 263.0 5.1 4.6e-78 262.8 0.1 2.6 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 EPE34059.1 - 0.0014 18.5 3.3 0.0014 18.5 3.3 3.4 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain DUF4201 PF13870.6 EPE34059.1 - 0.0015 18.3 6.9 0.005 16.6 5.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) COG2 PF06148.11 EPE34059.1 - 0.0084 16.2 2.9 0.0084 16.2 2.9 2.9 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 TMCCDC2 PF15844.5 EPE34059.1 - 0.031 14.2 0.7 0.75 9.7 0.7 2.5 1 1 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 COG5 PF10392.9 EPE34059.1 - 0.042 14.0 5.0 0.049 13.8 2.9 2.3 2 0 0 2 2 2 0 Golgi transport complex subunit 5 YfdX PF10938.8 EPE34059.1 - 0.11 12.5 0.2 0.11 12.5 0.2 3.4 3 1 1 4 4 4 0 YfdX protein CBFD_NFYB_HMF PF00808.23 EPE34060.1 - 1.1e-19 70.5 0.4 2.1e-19 69.6 0.4 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EPE34060.1 - 1.2e-14 54.8 0.2 2.1e-14 54.0 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EPE34060.1 - 0.054 13.8 0.0 0.091 13.1 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Fcf2 PF08698.11 EPE34062.1 - 1.7e-38 130.9 0.4 1.7e-38 130.9 0.4 2.1 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing tRNA-synt_1b PF00579.25 EPE34063.1 - 2.4e-67 227.3 0.0 3.1e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.22 EPE34063.1 - 2.7e-27 94.9 0.0 1.9e-26 92.2 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Spt4 PF06093.13 EPE34064.1 - 3.5e-31 107.1 0.1 4.5e-31 106.8 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.11 EPE34064.1 - 0.033 14.2 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Coronavirus gene 5 protein Kin17_mid PF10357.9 EPE34065.1 - 8.1e-54 180.9 0.9 1.7e-53 179.8 0.9 1.6 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 EPE34065.1 - 0.00018 21.8 1.3 0.00041 20.7 1.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EPE34065.1 - 0.0012 19.1 0.8 0.0027 17.9 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EPE34065.1 - 0.0085 16.4 3.7 0.011 16.0 0.1 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) GHMP_kinases_N PF00288.26 EPE34066.1 - 2.4e-11 43.7 0.3 5e-11 42.7 0.3 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EPE34066.1 - 0.002 18.4 0.1 0.036 14.4 0.1 2.3 1 1 1 2 2 2 1 GHMP kinases C terminal GARS_A PF01071.19 EPE34067.1 - 3.3e-84 281.5 0.2 9.6e-84 280.0 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 EPE34067.1 - 1.7e-34 119.2 0.0 3.2e-34 118.3 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 EPE34067.1 - 2.4e-32 111.6 0.1 1.5e-31 109.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EPE34067.1 - 3.8e-27 94.4 0.7 1.1e-26 92.9 0.7 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EPE34067.1 - 1.2e-14 54.7 2.0 3.5e-14 53.2 2.0 1.9 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 EPE34067.1 - 4.8e-06 26.3 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EPE34067.1 - 0.0009 18.8 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 EPE34067.1 - 0.0025 17.4 0.2 0.023 14.3 0.0 2.4 3 0 0 3 3 3 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EPE34067.1 - 0.0034 17.5 0.0 0.0085 16.2 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EPE34067.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_2 PF08442.10 EPE34067.1 - 0.018 14.6 0.0 0.06 12.9 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.6 EPE34067.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp SOR_SNZ PF01680.17 EPE34068.1 - 6.6e-111 369.0 6.7 9.9e-111 368.4 6.7 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EPE34068.1 - 8.9e-09 35.0 5.4 2.9e-06 26.8 0.1 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 EPE34068.1 - 0.0017 18.4 0.0 0.0043 17.1 0.0 1.6 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Dus PF01207.17 EPE34068.1 - 0.0063 15.6 0.4 0.25 10.4 0.0 2.4 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EPE34068.1 - 0.0081 15.7 0.6 0.15 11.5 0.0 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 EPE34068.1 - 0.021 14.0 0.2 0.69 9.0 0.0 2.4 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase NanE PF04131.14 EPE34068.1 - 0.024 13.8 1.1 0.19 10.9 0.0 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase FUN14 PF04930.15 EPE34069.1 - 6.9e-09 36.0 1.0 1.5e-08 34.9 1.0 1.5 1 0 0 1 1 1 1 FUN14 family Creatinase_N_2 PF16189.5 EPE34070.1 - 6.9e-53 179.0 0.8 6.3e-51 172.7 0.0 3.0 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EPE34070.1 - 1.1e-43 149.4 0.0 1.6e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EPE34070.1 - 8.7e-22 77.0 0.2 2.3e-21 75.6 0.2 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EPE34070.1 - 4e-19 69.6 0.0 1.7e-16 61.0 0.0 2.6 2 1 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Xpo1 PF08389.12 EPE34071.1 - 9.2e-09 35.5 9.2 2.3e-08 34.2 0.3 4.8 4 1 1 5 5 5 1 Exportin 1-like protein Importin_rep_3 PF18806.1 EPE34071.1 - 0.00071 19.6 0.1 0.0082 16.2 0.0 2.9 3 0 0 3 3 3 1 Importin 13 repeat Urb2 PF10441.9 EPE34071.1 - 0.0028 17.6 0.3 1.1 9.1 0.0 2.9 3 0 0 3 3 3 2 Urb2/Npa2 family TetR_C_19 PF17924.1 EPE34071.1 - 0.04 14.5 2.9 0.17 12.5 0.2 3.1 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Importin_rep PF18773.1 EPE34071.1 - 0.087 12.5 0.1 0.28 10.9 0.1 1.9 1 0 0 1 1 1 0 Importin 13 repeat IBN_N PF03810.19 EPE34071.1 - 0.15 12.0 1.0 0.52 10.3 0.1 2.4 2 0 0 2 2 2 0 Importin-beta N-terminal domain Sad1_UNC PF07738.13 EPE34072.1 - 3.7e-32 111.1 0.2 6.9e-32 110.2 0.2 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 EPE34072.1 - 0.00098 19.2 0.0 0.0029 17.7 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain ARD PF03079.14 EPE34073.1 - 7.7e-47 159.4 0.3 9e-47 159.2 0.3 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EPE34073.1 - 5.3e-08 32.5 0.1 8.7e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EPE34073.1 - 0.00028 20.8 0.1 0.0004 20.3 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Apt1 PF10351.9 EPE34074.1 - 2.9 6.6 12.8 3.5 6.4 12.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tmemb_cc2 PF10267.9 EPE34074.1 - 3.6 6.6 4.3 4.4 6.3 4.3 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Miga PF10265.9 EPE34074.1 - 8.5 5.2 7.9 10 4.9 7.9 1.1 1 0 0 1 1 1 0 Mitoguardin SPX PF03105.19 EPE34074.1 - 8.5 6.2 19.4 11 5.8 19.4 1.1 1 0 0 1 1 1 0 SPX domain adh_short PF00106.25 EPE34075.1 - 1.4e-32 112.8 0.0 2.1e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE34075.1 - 6.6e-22 78.2 0.0 1e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE34075.1 - 1.3e-10 41.5 0.0 1.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE34075.1 - 2.5e-05 23.8 0.1 5.1e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EPE34075.1 - 0.00083 18.5 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EPE34075.1 - 0.00091 18.4 0.0 0.0012 18.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EPE34075.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding NAD_binding_2 PF03446.15 EPE34075.1 - 0.062 13.5 0.1 0.31 11.2 0.1 1.9 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NmrA PF05368.13 EPE34075.1 - 0.062 12.8 0.1 0.16 11.5 0.1 1.6 2 0 0 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.19 EPE34075.1 - 0.093 11.7 0.1 0.15 11.0 0.1 1.3 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DER1 PF04511.15 EPE34076.1 - 6.3e-51 173.0 6.3 7.2e-51 172.8 6.3 1.0 1 0 0 1 1 1 1 Der1-like family Histone PF00125.24 EPE34077.1 - 9.1e-44 149.0 0.1 1.1e-43 148.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EPE34077.1 - 1.5e-05 25.1 0.0 2.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EPE34077.1 - 0.0016 18.8 0.0 0.0024 18.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EPE34077.1 - 0.035 14.4 0.0 0.054 13.8 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PI3_PI4_kinase PF00454.27 EPE34077.1 - 0.14 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase MMM1 PF10296.9 EPE34078.1 - 4.1e-141 469.8 0.0 2.9e-99 332.3 0.0 2.1 1 1 1 2 2 2 2 Maintenance of mitochondrial morphology protein 1 UAA PF08449.11 EPE34079.1 - 3.6e-07 29.7 14.8 4.4e-07 29.4 14.8 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EPE34079.1 - 0.00017 21.8 26.5 0.00053 20.2 9.8 2.3 2 1 0 2 2 2 2 EamA-like transporter family Thioredoxin PF00085.20 EPE34080.1 - 0.00017 21.5 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Xan_ur_permease PF00860.20 EPE34081.1 - 2.3e-29 102.3 28.6 7.3e-29 100.6 25.7 2.6 2 1 0 2 2 2 1 Permease family MFS_MOT1 PF16983.5 EPE34081.1 - 1.3 9.4 15.7 0.11 13.0 4.0 3.1 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Torus PF16131.5 EPE34082.1 - 5.3e-44 149.4 0.0 1.4e-43 148.0 0.0 1.7 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 EPE34082.1 - 1e-06 28.4 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EPE34082.1 - 0.00013 21.9 0.4 0.00013 21.9 0.4 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 EPE34082.1 - 0.0096 15.8 0.8 0.018 15.0 0.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.6 EPE34082.1 - 0.043 13.8 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Alpha_Helical PF18489.1 EPE34082.1 - 0.18 12.0 0.2 0.41 10.8 0.0 1.6 2 0 0 2 2 2 0 Alpha helical domain zf-CCCH_4 PF18044.1 EPE34082.1 - 0.47 10.3 2.0 1 9.2 2.0 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger UreF PF01730.16 EPE34083.1 - 1.1e-20 74.6 0.2 1.5e-20 74.1 0.2 1.2 1 0 0 1 1 1 1 UreF Sugarporin_N PF11471.8 EPE34083.1 - 0.0032 17.4 0.1 0.011 15.7 0.1 2.0 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension DUF429 PF04250.13 EPE34083.1 - 0.042 13.6 0.1 0.07 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF429) MARVEL PF01284.23 EPE34084.1 - 1.5e-20 73.7 6.0 1.9e-20 73.4 6.0 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF2721 PF11026.8 EPE34084.1 - 0.35 10.8 0.0 0.35 10.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) eRF1_2 PF03464.15 EPE34085.1 - 8.4e-48 162.1 0.1 1.4e-47 161.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EPE34085.1 - 4.4e-39 133.5 0.4 9.1e-39 132.4 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EPE34085.1 - 2.1e-21 76.3 0.0 3.4e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EPE34085.1 - 3.5e-10 40.3 0.0 6.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EPE34085.1 - 1e-08 35.6 0.0 1.7e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF1770 PF08589.10 EPE34086.1 - 2.2e-36 124.8 0.3 2.9e-36 124.4 0.3 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.6 EPE34087.1 - 3.2e-05 23.3 0.0 7.3e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Ribosomal_L2_C PF03947.18 EPE34088.1 - 8.1e-42 142.4 6.3 9.7e-42 142.1 5.0 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EPE34088.1 - 3.2e-15 55.8 0.1 8.4e-15 54.5 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.24 EPE34089.1 - 2.6e-65 220.7 0.1 2.9e-65 220.5 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EPE34089.1 - 0.0012 18.3 0.1 0.0024 17.3 0.1 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.9 EPE34090.1 - 4.4e-52 177.3 0.0 6.8e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EPE34090.1 - 4.7e-21 75.8 1.1 1.2e-20 74.5 1.1 1.8 1 0 0 1 1 1 1 Telomerase activating protein Est1 Imm8 PF15586.6 EPE34091.1 - 0.004 17.2 0.0 0.0064 16.5 0.0 1.3 1 0 0 1 1 1 1 Immunity protein 8 zf-C2H2_jaz PF12171.8 EPE34091.1 - 0.1 12.9 0.2 0.1 12.9 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EPE34091.1 - 0.12 12.8 12.1 2 9.0 1.2 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type ATG101 PF07855.12 EPE34092.1 - 8.4e-54 181.8 0.4 9.6e-54 181.6 0.4 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 Peroxin-3 PF04882.12 EPE34093.1 - 1.1e-174 581.9 0.0 1.2e-174 581.7 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 Sybindin PF04099.12 EPE34094.1 - 3.4e-27 95.1 0.0 4.2e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EPE34094.1 - 0.0077 16.3 0.1 0.011 15.9 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.25 EPE34095.1 - 1.2e-55 188.7 0.0 3.8e-49 167.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE34095.1 - 2.3e-32 112.3 0.0 7.7e-31 107.3 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE34095.1 - 2.2e-06 27.2 0.0 1.6e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EPE34095.1 - 0.0015 18.5 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EPE34095.1 - 0.015 14.1 0.0 0.058 12.2 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase G10 PF01125.17 EPE34096.1 - 2.3e-38 131.2 0.2 2.7e-38 131.0 0.2 1.0 1 0 0 1 1 1 1 G10 protein Complex1_LYR_2 PF13233.6 EPE34097.1 - 7e-06 26.7 0.3 1.1e-05 26.1 0.3 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EPE34097.1 - 7.8e-05 22.6 0.3 0.00015 21.7 0.3 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Vps51 PF08700.11 EPE34097.1 - 0.028 14.5 0.0 0.056 13.5 0.0 1.5 1 1 0 1 1 1 0 Vps51/Vps67 RNA_pol_L_2 PF13656.6 EPE34098.1 - 4e-34 116.2 0.0 5.7e-34 115.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EPE34098.1 - 1.1e-13 50.4 0.0 1.6e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.25 EPE34100.1 - 1.5e-50 172.1 0.0 2.5e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE34100.1 - 9.6e-28 97.2 0.0 1.8e-27 96.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EPE34100.1 - 0.0034 16.8 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPE34100.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EPE34100.1 - 0.098 12.2 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EPE34100.1 - 0.17 11.8 0.0 1.3 8.9 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family MPTase-PolyVal PF18818.1 EPE34101.1 - 0.14 12.2 0.4 0.24 11.5 0.4 1.4 1 0 0 1 1 1 0 Metallopeptidase superfamily domain DUF2423 PF10338.9 EPE34102.1 - 7.1e-18 64.6 2.3 1.5e-17 63.5 2.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Phosphodiest PF01663.22 EPE34102.1 - 8e-15 55.3 0.9 2.6e-09 37.1 0.0 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EPE34102.1 - 8.6e-06 25.4 0.0 3.6e-05 23.3 0.0 2.0 3 0 0 3 3 3 1 Sulfatase Metalloenzyme PF01676.18 EPE34102.1 - 0.032 13.6 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily PAXIP1_C PF15364.6 EPE34102.1 - 3.1 8.1 5.7 2.3 8.5 2.9 2.0 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein PINIT PF14324.6 EPE34103.1 - 8.9e-42 142.9 0.0 1.5e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 EPE34103.1 - 9.5e-22 76.5 5.2 1.6e-21 75.7 5.2 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EPE34103.1 - 8.6e-06 25.5 1.1 2e-05 24.3 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Vps36-NZF-N PF16988.5 EPE34103.1 - 0.054 12.9 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-C3HC4_4 PF15227.6 EPE34103.1 - 0.38 10.9 4.3 0.7 10.1 4.3 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING 6PF2K PF01591.18 EPE34104.1 - 1.5e-60 204.3 0.0 2e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EPE34104.1 - 5.3e-19 68.7 0.1 1.4e-18 67.3 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EPE34104.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Porin_3 PF01459.22 EPE34105.1 - 9.6e-86 287.6 0.4 1.1e-85 287.4 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Pkinase PF00069.25 EPE34107.1 - 9e-66 221.9 0.0 1.1e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE34107.1 - 1.5e-25 89.9 0.0 1.9e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE34107.1 - 1.5e-06 27.8 0.0 7.8e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EPE34107.1 - 0.0014 18.6 0.0 0.0074 16.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF1229 PF06797.11 EPE34107.1 - 0.021 15.0 0.2 0.034 14.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1229) Choline_kinase PF01633.20 EPE34107.1 - 0.086 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EPE34107.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EPE34107.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 MIF4G_like PF09088.11 EPE34108.1 - 1.5e-91 305.4 0.1 2.6e-91 304.6 0.1 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EPE34108.1 - 1.7e-73 247.4 0.0 3.7e-73 246.3 0.0 1.6 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.19 EPE34108.1 - 0.16 11.6 0.0 0.45 10.1 0.0 1.7 1 0 0 1 1 1 0 MIF4G domain RRM_1 PF00076.22 EPE34109.1 - 5.1e-33 112.7 0.0 1.9e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 EPE34109.1 - 0.0023 17.5 0.3 0.24 11.1 0.1 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain RRM_5 PF13893.6 EPE34109.1 - 0.0057 16.3 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPE34109.1 - 0.013 15.6 0.0 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif CMV_1a_C PF12503.8 EPE34109.1 - 0.095 12.7 0.1 3.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein C terminal Limkain-b1 PF11608.8 EPE34109.1 - 0.099 12.7 0.2 1.9 8.6 0.1 2.1 2 0 0 2 2 2 0 Limkain b1 Cas_Cas2CT1978 PF09707.10 EPE34109.1 - 0.12 12.5 0.0 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) Mito_carr PF00153.27 EPE34110.1 - 9.2e-51 169.8 6.3 3e-20 72.0 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.12 EPE34110.1 - 1.1e-19 69.8 0.1 2e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 TOM7 family PsbJ PF01788.17 EPE34110.1 - 0.91 9.4 0.0 0.91 9.4 0.0 3.5 5 0 0 5 5 5 0 PsbJ DUF1640 PF07798.11 EPE34111.1 - 1.7e-43 148.7 6.7 2.5e-43 148.1 6.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF3149 PF11346.8 EPE34111.1 - 0.00092 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3149) KCNQC3-Ank-G_bd PF11956.8 EPE34111.1 - 0.03 14.6 0.1 0.089 13.1 0.1 1.8 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 DUF1866 PF08952.11 EPE34112.1 - 0.018 14.9 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) bZIP_1 PF00170.21 EPE34112.1 - 0.036 14.2 2.1 0.036 14.2 2.1 1.6 2 0 0 2 2 2 0 bZIP transcription factor ATF7IP_BD PF16788.5 EPE34112.1 - 0.043 13.9 1.1 0.071 13.2 1.1 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain Methyltransf_9 PF08003.11 EPE34112.1 - 0.24 10.3 0.9 0.36 9.7 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Vps51 PF08700.11 EPE34113.1 - 3e-11 43.2 0.0 1.4e-10 41.1 0.0 2.2 1 0 0 1 1 1 1 Vps51/Vps67 HrpJ PF07201.11 EPE34113.1 - 3.8 7.8 9.0 5.1 7.4 0.2 3.5 4 0 0 4 4 4 0 HrpJ-like domain ELFV_dehydrog PF00208.21 EPE34114.1 - 1.1e-63 215.2 0.0 2e-63 214.4 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EPE34114.1 - 2.1e-19 68.7 0.0 6.7e-15 53.8 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EPE34114.1 - 0.078 12.9 0.0 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Aminotran_5 PF00266.19 EPE34115.1 - 4.1e-12 45.7 0.0 5.7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cohesin_load PF10345.9 EPE34116.1 - 6.8e-146 487.2 0.0 8.7e-146 486.8 0.0 1.0 1 0 0 1 1 1 1 Cohesin loading factor Abhydrolase_1 PF00561.20 EPE34117.1 - 5.8e-11 42.5 0.0 9.5e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE34117.1 - 1.7e-05 24.2 0.0 6.1e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 IGPD PF00475.18 EPE34119.1 - 5.8e-58 195.3 0.4 7.4e-58 194.9 0.4 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Rep_fac_C PF08542.11 EPE34121.1 - 7.3e-24 84.0 0.2 2.6e-23 82.2 0.0 2.1 3 0 0 3 3 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EPE34121.1 - 1.8e-12 47.3 0.0 4.1e-09 36.4 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EPE34121.1 - 4.8e-11 43.2 0.0 1.1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EPE34121.1 - 1e-06 28.8 0.0 4.6e-06 26.7 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 EPE34121.1 - 4.8e-06 27.1 0.0 0.00041 20.8 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EPE34121.1 - 4.2e-05 23.3 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EPE34121.1 - 0.00015 22.0 0.1 0.76 10.1 0.1 3.0 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 EPE34121.1 - 0.00017 21.4 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 EPE34121.1 - 0.00019 21.3 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 EPE34121.1 - 0.0011 18.7 0.1 0.002 18.0 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EPE34121.1 - 0.0026 17.7 0.0 0.0055 16.6 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 EPE34121.1 - 0.0062 15.9 0.0 0.067 12.6 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 EPE34121.1 - 0.0073 16.6 0.0 0.022 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain TniB PF05621.11 EPE34121.1 - 0.0085 15.5 0.1 2.6 7.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein MeaB PF03308.16 EPE34121.1 - 0.01 14.9 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_11 PF13086.6 EPE34121.1 - 0.015 15.1 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EPE34121.1 - 0.017 14.9 0.1 0.77 9.5 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_24 PF13479.6 EPE34121.1 - 0.022 14.5 0.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EPE34121.1 - 0.026 14.2 0.1 0.079 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EPE34121.1 - 0.026 14.1 0.0 0.1 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 EPE34121.1 - 0.027 13.9 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.6 EPE34121.1 - 0.029 14.7 0.3 0.15 12.4 0.3 2.2 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EPE34121.1 - 0.036 14.0 0.3 0.13 12.2 0.1 2.0 1 1 1 2 2 2 0 NTPase AAA_5 PF07728.14 EPE34121.1 - 0.073 13.1 0.1 0.33 10.9 0.0 2.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DNA_pol3_gamma3 PF12169.8 EPE34121.1 - 0.13 12.1 0.4 1.3 8.9 0.0 2.6 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III Cupin_1 PF00190.22 EPE34122.1 - 1.3e-16 60.5 0.5 2e-16 60.0 0.5 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 EPE34122.1 - 0.047 13.4 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Cupin domain Glyco_hydro_18 PF00704.28 EPE34124.1 - 8.3e-64 216.3 0.1 9.8e-64 216.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL15 PF14885.6 EPE34124.1 - 0.00049 20.1 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Hypothetical glycosyl hydrolase family 15 Pet127 PF08634.10 EPE34125.1 - 8.4e-120 399.3 3.2 1.3e-119 398.7 3.2 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Peptidase_C48 PF02902.19 EPE34126.1 - 3.7e-38 131.5 0.0 8.4e-38 130.4 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3435 PF11917.8 EPE34129.1 - 0.01 14.8 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF410 PF04190.13 EPE34130.1 - 2.6e-91 306.0 0.0 3.1e-91 305.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPALS PF18178.1 EPE34131.1 - 0.026 13.9 0.1 0.038 13.4 0.1 1.2 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family RAI1 PF08652.11 EPE34132.1 - 2e-26 91.9 0.0 4.5e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Malic_M PF03949.15 EPE34133.1 - 2.7e-96 321.8 0.0 3.4e-96 321.5 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EPE34133.1 - 2.6e-62 209.8 0.0 4.1e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain EF-hand_9 PF14658.6 EPE34133.1 - 0.12 12.7 0.2 23 5.4 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain OPT PF03169.15 EPE34134.1 - 1.3e-152 509.6 23.1 1.5e-152 509.4 23.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SWIB PF02201.18 EPE34135.1 - 2.6e-19 68.8 0.0 6.4e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain Sporozoite_P67 PF05642.11 EPE34135.1 - 2.4 6.1 5.4 3.3 5.7 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 EPE34135.1 - 3 7.1 10.0 4.9 6.4 10.0 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EPE34135.1 - 3.9 7.9 13.1 6.9 7.1 11.2 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Mo25 PF08569.11 EPE34136.1 - 9.8e-131 436.0 0.1 1.1e-130 435.8 0.1 1.0 1 0 0 1 1 1 1 Mo25-like Methyltransf_25 PF13649.6 EPE34137.1 - 1.8e-12 47.8 0.0 5e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EPE34137.1 - 2.2e-11 43.7 0.1 4.6e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EPE34137.1 - 2.1e-10 41.1 0.0 6.4e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE34137.1 - 1.5e-09 37.9 0.0 2.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE34137.1 - 2.3e-06 27.6 0.0 6e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EPE34137.1 - 3.4e-06 27.0 0.0 6.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPE34137.1 - 5.5e-06 26.0 0.1 9.9e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EPE34137.1 - 1.8e-05 24.2 0.0 3.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EPE34137.1 - 0.00063 20.4 0.1 0.0016 19.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE34137.1 - 0.0016 17.8 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EPE34137.1 - 0.0078 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 EPE34137.1 - 0.0089 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 EPE34137.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EPE34137.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 EPE34137.1 - 0.015 14.2 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.18 EPE34137.1 - 0.018 14.3 0.1 0.048 12.9 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain TehB PF03848.14 EPE34137.1 - 0.025 14.0 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB UPF0020 PF01170.18 EPE34137.1 - 0.053 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.6 EPE34137.1 - 0.13 13.3 0.0 0.61 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 EPE34137.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain KASH_CCD PF14662.6 EPE34137.1 - 0.14 11.9 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Cons_hypoth95 PF03602.15 EPE34137.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 WD40_alt PF14077.6 EPE34137.1 - 0.57 10.1 1.8 0.83 9.6 0.7 1.8 1 1 1 2 2 2 0 Alternative WD40 repeat motif Pyridox_ox_2 PF12900.7 EPE34138.1 - 4.2e-36 124.1 0.0 6.1e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AA_permease PF00324.21 EPE34140.1 - 2.1e-66 224.5 29.5 6.9e-66 222.8 29.5 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE34140.1 - 6.2e-24 84.6 25.3 8.5e-24 84.2 25.3 1.2 1 0 0 1 1 1 1 Amino acid permease DUF983 PF06170.12 EPE34140.1 - 0.24 11.8 5.0 0.81 10.1 2.0 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF2039 PF10217.9 EPE34141.1 - 0.16 12.4 2.8 1 9.8 1.8 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Glyco_hydro_35 PF01301.19 EPE34142.1 - 4.1e-82 276.3 2.0 6.9e-82 275.6 2.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EPE34142.1 - 3.1e-59 198.5 8.7 1.9e-33 115.5 0.1 3.7 3 1 1 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 EPE34142.1 - 2.5e-55 187.1 0.3 4.9e-55 186.2 0.3 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 EPE34142.1 - 2.1e-24 84.9 0.2 5.8e-24 83.5 0.1 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 EPE34142.1 - 0.00018 21.0 0.1 0.0006 19.3 0.1 1.8 1 1 1 2 2 2 1 Beta-galactosidase Cellulase PF00150.18 EPE34142.1 - 0.02 14.3 0.1 0.043 13.2 0.1 1.5 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Polysacc_deac_1 PF01522.21 EPE34144.1 - 1.4e-28 99.3 0.0 2.3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EPE34144.1 - 1.8e-22 79.5 90.6 1.7e-09 38.0 19.2 5.3 5 0 0 5 5 5 4 Chitin recognition protein MSA-2c PF12238.8 EPE34144.1 - 0.023 14.7 2.2 0.041 13.9 2.2 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c CDC27 PF09507.10 EPE34144.1 - 0.13 11.7 3.1 0.18 11.1 3.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Csm1 PF12539.8 EPE34145.1 - 1e-29 103.0 0.3 2.4e-29 101.8 0.3 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 BRE1 PF08647.11 EPE34145.1 - 0.0018 18.3 8.4 0.0018 18.3 8.4 3.3 2 2 0 3 3 3 1 BRE1 E3 ubiquitin ligase COG2 PF06148.11 EPE34145.1 - 0.11 12.5 3.3 0.3 11.2 3.3 1.7 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2024 PF09630.10 EPE34145.1 - 0.14 12.1 0.0 0.45 10.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) Spc42p PF11544.8 EPE34145.1 - 0.75 9.8 7.4 0.26 11.3 2.6 2.8 1 1 2 3 3 3 0 Spindle pole body component Spc42p HalX PF08663.10 EPE34145.1 - 1.6 9.1 8.4 6.4 7.2 0.6 3.0 2 0 0 2 2 2 0 HalX domain Cep57_MT_bd PF06657.13 EPE34145.1 - 2.3 8.7 15.0 0.14 12.6 4.5 3.3 3 1 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF3138 PF11336.8 EPE34145.1 - 3.8 6.0 8.4 6.5 5.2 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Sulfatase_C PF14707.6 EPE34145.1 - 4.3 8.1 5.5 1.3 9.8 0.5 2.3 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase Bap31_Bap29_C PF18035.1 EPE34145.1 - 5.4 7.1 10.8 5.8 7.0 6.2 2.7 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Fungal_trans PF04082.18 EPE34147.1 - 5.7e-34 117.3 0.0 1.2e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE34147.1 - 0.022 14.9 3.9 0.04 14.0 3.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PigN PF04987.14 EPE34148.1 - 1.8e-139 465.6 32.0 3.4e-89 299.8 14.9 2.1 2 0 0 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EPE34148.1 - 5.9e-10 39.3 2.1 4.5e-08 33.1 2.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EPE34148.1 - 4.9e-09 36.0 0.1 7.8e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EPE34148.1 - 2.5e-05 23.8 0.0 4.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Isochorismatase PF00857.20 EPE34149.1 - 1.6e-30 106.5 0.0 2e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF3716 PF12511.8 EPE34150.1 - 3.2e-14 52.7 4.4 5.7e-14 51.9 4.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF4246 PF14033.6 EPE34151.1 - 8.4e-161 536.1 0.0 9.7e-161 535.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Arv1 PF04161.13 EPE34152.1 - 6.7e-62 209.4 5.6 3.6e-59 200.5 5.6 2.0 1 1 0 1 1 1 1 Arv1-like family ATP_synt_H PF05493.13 EPE34153.1 - 1.1e-23 83.4 5.2 1.3e-23 83.2 5.2 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Pox_A14 PF05767.12 EPE34153.1 - 0.026 14.7 1.2 0.031 14.4 1.2 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 ABC2_membrane_2 PF12679.7 EPE34153.1 - 0.55 9.5 3.6 0.65 9.2 3.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein CPP1-like PF11833.8 EPE34153.1 - 0.58 9.8 3.8 0.65 9.6 3.8 1.0 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like NAD_binding_2 PF03446.15 EPE34154.1 - 1.6e-30 106.3 0.1 2.6e-30 105.7 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EPE34154.1 - 1.8e-12 47.7 0.0 6.2e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EPE34154.1 - 9.6e-10 38.7 0.0 2.1e-09 37.6 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 EPE34154.1 - 7.8e-09 35.8 0.1 2.1e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase UDPG_MGDP_dh_N PF03721.14 EPE34154.1 - 0.0013 18.4 0.2 0.0059 16.2 0.2 2.0 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 EPE34154.1 - 0.0021 18.3 0.1 0.0042 17.3 0.1 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EPE34154.1 - 0.006 16.8 0.1 0.022 15.0 0.1 2.0 1 1 0 1 1 1 1 TrkA-N domain OCD_Mu_crystall PF02423.15 EPE34154.1 - 0.0073 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Semialdhyde_dh PF01118.24 EPE34154.1 - 0.042 14.3 0.0 0.091 13.2 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EPE34154.1 - 0.043 13.7 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding GFO_IDH_MocA PF01408.22 EPE34154.1 - 0.12 13.2 0.0 0.3 11.9 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold FRQ PF09421.10 EPE34155.1 - 1e-165 553.5 41.2 5.8e-164 547.7 41.3 2.5 1 1 0 1 1 1 1 Frequency clock protein DUF4472 PF14739.6 EPE34155.1 - 0.0015 19.2 0.3 0.0049 17.6 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) Leu_zip PF15294.6 EPE34155.1 - 0.0096 15.5 0.4 0.072 12.6 0.0 2.1 2 0 0 2 2 2 1 Leucine zipper DUF3907 PF13047.6 EPE34155.1 - 0.15 12.0 0.3 4.2 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) CoA_trans PF01144.23 EPE34157.1 - 1e-100 335.6 3.9 1.2e-61 207.9 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EPE34157.1 - 0.0072 16.3 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Glyco_hydro_47 PF01532.20 EPE34159.1 - 1.1e-188 627.8 0.1 1.5e-188 627.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Cpn60_TCP1 PF00118.24 EPE34160.1 - 1.2e-159 532.1 0.6 1.4e-159 531.9 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Prenylcys_lyase PF07156.14 EPE34161.1 - 1.9e-87 293.7 0.0 2.5e-87 293.4 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 EPE34161.1 - 5.3e-13 49.0 0.1 1.5e-12 47.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EPE34161.1 - 8.5e-10 38.5 0.0 4.4e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EPE34161.1 - 9.6e-06 25.4 0.5 8.8e-05 22.2 0.5 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE34161.1 - 0.00066 19.0 0.1 0.0056 16.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPE34161.1 - 0.0093 16.0 0.1 0.064 13.2 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EPE34161.1 - 0.029 13.6 0.6 0.12 11.6 0.2 1.9 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 EPE34161.1 - 0.057 12.7 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EPE34161.1 - 0.12 12.9 0.6 2 9.1 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CP2 PF04516.15 EPE34162.1 - 7.9e-84 280.5 0.0 1.5e-83 279.7 0.0 1.4 1 0 0 1 1 1 1 CP2 transcription factor AKNA PF12443.8 EPE34162.1 - 0.047 14.3 0.3 0.047 14.3 0.3 2.8 3 0 0 3 3 3 0 AT-hook-containing transcription factor Tektin PF03148.14 EPE34162.1 - 0.084 11.6 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Tektin family TMF_DNA_bd PF12329.8 EPE34162.1 - 0.21 11.6 0.2 0.47 10.5 0.2 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HET PF06985.11 EPE34166.1 - 8.8e-29 100.7 0.3 1.7e-28 99.8 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) E1-E2_ATPase PF00122.20 EPE34166.1 - 0.025 14.1 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 E1-E2 ATPase Peptidase_S41 PF03572.18 EPE34167.1 - 5.3e-08 32.6 0.0 2.1e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Peptidase family S41 Fructosamin_kin PF03881.14 EPE34169.1 - 8e-32 110.6 0.0 1.1e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase Fungal_trans_2 PF11951.8 EPE34170.1 - 3.6e-05 22.8 0.2 6.2e-05 22.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PHD PF00628.29 EPE34170.1 - 0.084 12.8 0.9 0.14 12.1 0.9 1.3 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 EPE34170.1 - 0.12 12.3 0.8 0.23 11.4 0.8 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DLH PF01738.18 EPE34171.1 - 2.1e-06 27.4 0.0 3.4e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family ADH_zinc_N_2 PF13602.6 EPE34172.1 - 5.9e-21 75.9 0.0 9.8e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPE34172.1 - 4.8e-16 58.9 0.1 8e-16 58.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EPE34172.1 - 0.0041 16.6 0.0 0.0063 16.0 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus DUF4058 PF13267.6 EPE34173.1 - 0.13 11.7 3.2 0.21 11.0 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) SKG6 PF08693.10 EPE34174.1 - 0.08 12.4 0.2 0.17 11.3 0.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FAM117 PF15388.6 EPE34174.1 - 0.25 10.7 0.0 0.25 10.7 0.0 1.4 2 0 0 2 2 2 0 Protein Family FAM117 Zn_clus PF00172.18 EPE34175.1 - 0.0001 22.3 12.3 0.0001 22.3 12.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Isochorismatase PF00857.20 EPE34176.1 - 1.2e-37 129.8 0.0 1.4e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family COesterase PF00135.28 EPE34177.1 - 2.2e-76 257.8 0.0 1.6e-75 255.0 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE34177.1 - 1.9e-07 31.2 0.1 1.2e-06 28.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPE34177.1 - 0.096 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Zn_clus PF00172.18 EPE34179.1 - 9.9e-07 28.8 10.0 1.8e-06 28.0 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 EPE34180.1 - 5.6e-14 52.6 0.0 1.3e-13 51.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE34180.1 - 0.011 15.3 0.0 0.068 12.7 0.0 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase Pax2_C PF12403.8 EPE34180.1 - 0.017 15.2 0.1 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 Paired-box protein 2 C terminal DUF1679 PF07914.11 EPE34180.1 - 0.041 12.7 0.0 3.9 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 EPE34180.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase ECR1_N PF14382.6 EPE34181.1 - 5.4e-17 61.3 0.3 1e-16 60.4 0.3 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EPE34181.1 - 1.4e-06 28.5 0.9 2.8e-06 27.6 0.9 1.4 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 EPE34181.1 - 0.029 15.0 1.6 2.3 8.8 0.1 3.5 4 0 0 4 4 4 0 Exosome component EXOSC1/CSL4 S1 PF00575.23 EPE34181.1 - 0.039 14.3 0.7 1.7 9.0 0.0 2.9 3 0 0 3 3 3 0 S1 RNA binding domain ADH_N PF08240.12 EPE34182.1 - 7.3e-23 80.5 1.6 1.3e-22 79.7 1.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE34182.1 - 2.9e-14 53.2 0.0 5.5e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EPE34182.1 - 0.00018 21.0 0.1 0.00034 20.0 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EPE34182.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EPE34182.1 - 0.06 13.2 0.2 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EPE34182.1 - 0.079 13.1 0.6 0.17 12.0 0.1 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF4536 PF15055.6 EPE34183.1 - 3.7e-08 33.5 2.1 2.3e-06 27.7 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4536) Adap_comp_sub PF00928.21 EPE34184.1 - 1e-68 231.6 0.0 1.3e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EPE34184.1 - 0.00073 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SNF2_N PF00176.23 EPE34187.1 - 1.5e-71 240.9 0.2 3e-71 240.0 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EPE34187.1 - 4.2e-41 139.5 0.8 1.4e-40 137.8 0.8 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 EPE34187.1 - 4.3e-37 127.2 2.0 4.3e-37 127.2 2.0 3.3 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 EPE34187.1 - 3e-18 66.2 0.0 1.6e-17 63.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE34187.1 - 2.3e-09 37.5 0.0 9.9e-09 35.4 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EPE34187.1 - 0.00023 21.0 0.0 0.00071 19.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EPE34187.1 - 0.00037 19.7 0.0 0.0011 18.3 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF1086 PF06461.11 EPE34187.1 - 0.00059 19.7 0.1 0.0016 18.3 0.1 1.7 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) Myb_DNA-binding PF00249.31 EPE34187.1 - 0.0006 20.0 0.2 0.67 10.2 0.0 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain SWI2_SNF2 PF18766.1 EPE34187.1 - 0.00099 18.8 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD_2 PF06733.15 EPE34187.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 DUF4588 PF15251.6 EPE34188.1 - 8.7e-06 25.7 2.0 1.7e-05 24.7 2.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) HAD_2 PF13419.6 EPE34189.1 - 5.4e-11 42.9 0.0 6.9e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPE34189.1 - 5.1e-06 26.9 0.0 6.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPE34189.1 - 0.00023 21.2 0.1 0.00036 20.5 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Pkinase PF00069.25 EPE34190.1 - 2.2e-63 214.1 0.0 2.9e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE34190.1 - 7e-40 136.9 0.0 9.3e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPE34190.1 - 0.00019 20.4 0.0 0.0004 19.3 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EPE34190.1 - 0.00019 20.9 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EPE34190.1 - 0.044 12.7 0.0 0.07 12.1 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain SH2_2 PF14633.6 EPE34191.1 - 2.5e-87 291.8 0.0 5e-87 290.8 0.0 1.5 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 EPE34191.1 - 4.6e-37 127.0 0.9 4.6e-37 127.0 0.9 2.1 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 EPE34191.1 - 3.5e-32 110.8 0.0 7.3e-32 109.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EPE34191.1 - 4.8e-30 104.3 0.0 1.4e-29 102.9 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 EPE34191.1 - 3.5e-19 69.2 23.4 3.5e-19 69.2 23.4 6.0 4 1 3 7 7 7 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 EPE34191.1 - 1e-05 26.3 3.1 0.00041 21.2 2.5 3.9 2 1 0 2 2 2 1 HHH domain HHH_3 PF12836.7 EPE34191.1 - 0.0027 17.9 0.0 0.014 15.6 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif SAM_Exu PF18609.1 EPE34191.1 - 0.042 13.9 1.6 1 9.5 0.1 3.0 2 0 0 2 2 2 0 Exuperantia SAM-like domain B12-binding PF02310.19 EPE34191.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Oxysterol_BP PF01237.18 EPE34192.1 - 1.4e-107 359.8 0.0 3.4e-107 358.5 0.0 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 EPE34192.1 - 2e-37 127.3 2.1 3.6e-37 126.5 0.1 2.4 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 EPE34192.1 - 2.7e-06 27.8 0.0 5.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 PH domain GOLD_2 PF13897.6 EPE34192.1 - 0.0022 18.5 0.0 0.0062 17.0 0.0 1.7 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking Amidohydro_2 PF04909.14 EPE34193.1 - 0.00012 21.9 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Catalase_C PF18011.1 EPE34193.1 - 0.031 13.9 0.0 0.13 11.9 0.0 2.2 2 1 0 2 2 2 0 C-terminal domain found in long catalases SMN PF06003.12 EPE34195.1 - 7.9 5.6 9.8 22 4.2 9.8 1.7 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) zf-PHD-like PF15446.6 EPE34196.1 - 1.3e-67 226.6 12.2 3.5e-67 225.2 12.2 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 EPE34196.1 - 2.1e-51 174.7 0.3 3.9e-51 173.8 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE34196.1 - 6.2e-20 71.6 0.0 1.9e-19 70.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EPE34196.1 - 4.8e-12 45.7 0.1 4.8e-12 45.7 0.1 1.8 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 EPE34196.1 - 0.0002 21.2 4.2 0.0002 21.2 4.2 3.3 3 1 0 3 3 3 1 PHD-finger Chromo PF00385.24 EPE34196.1 - 0.00037 20.3 5.0 0.077 12.9 2.5 2.8 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF1087 PF06465.13 EPE34196.1 - 0.0023 17.9 1.8 0.0037 17.3 0.0 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1087) PHD_2 PF13831.6 EPE34196.1 - 0.0032 17.0 5.8 0.0032 17.0 5.8 2.8 2 1 0 2 2 2 1 PHD-finger ResIII PF04851.15 EPE34196.1 - 0.0033 17.4 0.0 0.012 15.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit C1_1 PF00130.22 EPE34196.1 - 0.43 10.5 7.9 2.5 8.1 1.4 3.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ferric_reduct PF01794.19 EPE34197.1 - 6.8e-21 74.7 6.2 6.8e-21 74.7 6.2 3.1 3 1 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EPE34197.1 - 9.1e-13 48.6 0.0 1.3e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EPE34197.1 - 1.1e-10 41.6 0.0 2e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 FAD-binding domain Tom7 PF08038.12 EPE34197.1 - 0.015 15.0 0.0 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 TOM7 family E1-E2_ATPase PF00122.20 EPE34198.1 - 8e-38 129.8 0.4 8e-38 129.8 0.4 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EPE34198.1 - 5.6e-33 114.2 5.1 5.6e-33 114.2 5.1 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EPE34198.1 - 2.1e-20 73.9 0.0 1.4e-09 38.5 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPE34198.1 - 2.4e-14 53.2 0.0 5.2e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EPE34198.1 - 1.5e-11 43.8 0.0 4.2e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EPE34198.1 - 0.00042 20.2 0.3 0.0012 18.6 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Phage_connector PF05352.12 EPE34198.1 - 0.093 12.1 0.3 0.19 11.1 0.1 1.5 2 0 0 2 2 2 0 Phage Connector (GP10) Fer2 PF00111.27 EPE34200.1 - 2.5e-10 40.2 2.9 3.6e-10 39.7 2.9 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.12 EPE34201.1 - 5.2e-32 111.0 7.4 5.2e-32 111.0 7.4 2.1 2 1 0 2 2 2 1 Rrp15p SRP54 PF00448.22 EPE34202.1 - 1.5e-76 256.4 3.1 2.2e-76 255.9 1.8 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EPE34202.1 - 8.9e-31 106.5 4.7 8.9e-31 106.5 4.7 4.1 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 EPE34202.1 - 8.3e-21 74.0 0.5 2.8e-20 72.3 0.6 1.9 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EPE34202.1 - 4e-07 29.8 1.1 2.6e-06 27.1 1.2 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EPE34202.1 - 2e-06 28.0 0.1 4.1e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EPE34202.1 - 4e-06 26.2 0.0 9.6e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 EPE34202.1 - 1.8e-05 25.2 0.2 1.8e-05 25.2 0.2 2.5 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 EPE34202.1 - 0.00013 22.4 0.0 0.00026 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 EPE34202.1 - 0.00018 20.6 1.0 0.0014 17.7 1.0 2.2 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 EPE34202.1 - 0.001 19.0 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_30 PF13604.6 EPE34202.1 - 0.0016 18.2 0.0 0.0052 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EPE34202.1 - 0.003 17.6 0.0 0.0093 16.0 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 EPE34202.1 - 0.0033 17.2 0.4 0.019 14.8 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EPE34202.1 - 0.0042 17.6 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EPE34202.1 - 0.006 16.3 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Thymidylate kinase ResIII PF04851.15 EPE34202.1 - 0.0076 16.3 0.5 0.033 14.2 0.5 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Torsin PF06309.11 EPE34202.1 - 0.0081 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_22 PF13401.6 EPE34202.1 - 0.0095 16.2 0.0 0.029 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EPE34202.1 - 0.012 15.7 0.7 0.051 13.7 0.2 2.3 2 1 0 2 2 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EPE34202.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EPE34202.1 - 0.014 15.3 0.1 0.042 13.8 0.0 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.10 EPE34202.1 - 0.022 14.2 1.7 6.2 6.2 1.8 3.0 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit 6PF2K PF01591.18 EPE34202.1 - 0.025 13.9 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_31 PF13614.6 EPE34202.1 - 0.035 14.0 0.2 0.5 10.3 0.2 2.4 1 1 1 2 2 2 0 AAA domain Tex_YqgF PF16921.5 EPE34202.1 - 0.049 14.1 0.2 0.21 12.0 0.0 2.2 2 0 0 2 2 2 0 Tex protein YqgF-like domain Spectrin PF00435.21 EPE34202.1 - 0.068 13.7 0.3 0.2 12.2 0.1 1.8 2 0 0 2 2 1 0 Spectrin repeat NTPase_1 PF03266.15 EPE34202.1 - 0.074 13.0 1.4 0.7 9.8 1.4 2.2 1 1 0 1 1 1 0 NTPase AAA PF00004.29 EPE34202.1 - 0.084 13.3 0.2 0.25 11.8 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EPE34202.1 - 0.12 12.7 0.1 0.12 12.7 0.1 2.0 2 0 0 2 2 1 0 AAA domain DUF3052 PF11253.8 EPE34202.1 - 0.13 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) AAA PF00004.29 EPE34203.1 - 2.6e-40 137.9 1.1 4.6e-14 53.0 0.0 5.7 6 0 0 6 6 5 3 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 EPE34203.1 - 1.1e-38 132.9 0.1 5.2e-38 130.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EPE34203.1 - 4.1e-25 89.1 27.7 9.2e-23 81.3 0.0 6.7 6 0 0 6 6 6 2 AAA domain AAA_30 PF13604.6 EPE34203.1 - 1.8e-16 60.5 0.9 0.1 12.3 0.0 5.5 5 0 0 5 5 5 5 AAA domain AAA_lid_6 PF17866.1 EPE34203.1 - 5.2e-15 55.4 5.4 1.8e-06 28.0 1.7 3.0 2 0 0 2 2 2 2 AAA lid domain AAA_19 PF13245.6 EPE34203.1 - 1.2e-13 51.7 3.4 6.6e-06 26.5 0.0 5.4 4 2 0 4 4 4 3 AAA domain AAA_5 PF07728.14 EPE34203.1 - 2.3e-11 43.8 4.1 0.047 13.7 0.0 5.7 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPE34203.1 - 2.6e-11 43.9 8.4 0.14 12.4 0.1 7.2 5 2 0 5 5 5 3 AAA domain AAA_16 PF13191.6 EPE34203.1 - 2.8e-09 37.6 2.2 0.1 13.0 0.2 5.3 4 0 0 4 4 4 3 AAA ATPase domain Mg_chelatase PF01078.21 EPE34203.1 - 1.6e-07 30.9 0.3 0.13 11.6 0.0 4.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EPE34203.1 - 3.5e-07 30.1 0.6 0.13 12.0 0.0 4.3 4 1 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EPE34203.1 - 6.3e-07 29.7 7.7 0.48 10.6 0.0 5.5 4 0 0 4 4 4 2 AAA domain ATPase PF06745.13 EPE34203.1 - 4.3e-06 26.3 1.6 0.0092 15.4 0.0 4.5 4 0 0 4 4 4 1 KaiC RNA_helicase PF00910.22 EPE34203.1 - 1.1e-05 25.7 0.7 6.9 7.1 0.0 4.7 4 0 0 4 4 4 0 RNA helicase IstB_IS21 PF01695.17 EPE34203.1 - 7.2e-05 22.6 0.2 10 5.8 0.0 4.6 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_7 PF12775.7 EPE34203.1 - 0.00036 20.1 1.5 2.2 7.8 0.0 4.3 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_18 PF13238.6 EPE34203.1 - 0.0013 19.3 17.8 2.4 8.7 0.0 5.8 6 0 0 6 6 4 2 AAA domain AAA_24 PF13479.6 EPE34203.1 - 0.003 17.3 8.3 0.7 9.6 0.0 4.5 4 1 0 4 4 4 1 AAA domain Torsin PF06309.11 EPE34203.1 - 0.0041 17.2 0.1 67 3.6 0.0 4.4 4 0 0 4 4 4 0 Torsin Helicase_RecD PF05127.14 EPE34203.1 - 0.034 14.0 0.0 3.3 7.5 0.0 3.5 3 0 0 3 3 2 0 Helicase AAA_6 PF12774.7 EPE34203.1 - 0.043 12.8 0.1 16 4.3 0.0 3.4 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region PhoH PF02562.16 EPE34203.1 - 0.079 12.4 1.7 25 4.2 0.0 4.1 4 0 0 4 4 4 0 PhoH-like protein AAA_28 PF13521.6 EPE34203.1 - 0.14 12.4 12.5 3.6 7.8 0.0 5.7 5 0 0 5 5 5 0 AAA domain DUF2075 PF09848.9 EPE34203.1 - 0.47 9.6 0.0 0.47 9.6 0.0 5.6 7 1 0 7 7 5 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EPE34203.1 - 1.5 8.7 8.9 19 5.2 0.2 4.3 4 0 0 4 4 4 0 NTPase SRP54 PF00448.22 EPE34203.1 - 2.6 7.6 8.2 0.69 9.5 0.2 3.8 3 1 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 EPE34203.1 - 2.9 7.4 7.6 26 4.3 0.0 4.4 4 0 0 4 4 4 0 AAA domain AAA_17 PF13207.6 EPE34203.1 - 3.6 8.0 19.0 6.4 7.2 0.1 5.7 5 0 0 5 5 5 0 AAA domain HET PF06985.11 EPE34206.1 - 1.1e-07 32.4 3.4 8.6e-06 26.2 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ADH_zinc_N PF00107.26 EPE34207.1 - 4.1e-21 75.3 0.0 1e-20 74.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE34207.1 - 2.5e-17 64.2 0.0 4e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE34207.1 - 2.7e-08 33.7 0.0 1.1e-07 31.6 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain WD40 PF00400.32 EPE34208.1 - 2.9e-26 91.2 0.0 2.4e-07 31.3 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE34208.1 - 2.8e-14 53.2 0.2 0.012 15.9 0.0 5.2 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE34208.1 - 7.7e-05 22.7 0.6 0.0094 15.8 0.1 3.0 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EPE34208.1 - 8.8e-05 21.7 0.6 0.096 11.7 0.1 2.3 1 1 1 2 2 2 2 Coatomer WD associated region WD40_like PF17005.5 EPE34208.1 - 0.001 18.5 0.1 0.037 13.3 0.1 2.8 1 1 1 2 2 2 1 WD40-like domain PQQ_2 PF13360.6 EPE34208.1 - 0.0013 18.4 0.2 0.015 14.9 0.2 2.5 1 1 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.16 EPE34208.1 - 0.0061 15.1 0.3 0.098 11.2 0.0 2.4 2 1 0 2 2 2 1 Cytochrome D1 heme domain Gmad1 PF10647.9 EPE34208.1 - 0.027 14.2 0.4 0.079 12.7 0.4 1.7 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 EPE34208.1 - 0.059 12.0 0.1 0.14 10.7 0.1 1.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 FTHFS PF01268.19 EPE34209.1 - 5.8e-254 843.4 0.4 8.2e-254 842.9 0.4 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EPE34209.1 - 7.6e-65 217.1 1.2 7.6e-65 217.1 1.2 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EPE34209.1 - 4.3e-37 126.9 0.5 9.6e-37 125.8 0.5 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.27 EPE34209.1 - 0.03 13.9 0.4 0.09 12.3 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Fungal_TACC PF12709.7 EPE34210.1 - 2.5e-10 40.6 1.1 2.5e-10 40.6 1.1 4.1 3 1 1 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins Shugoshin_N PF07558.11 EPE34210.1 - 0.13 12.1 1.3 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region NPV_P10 PF05531.12 EPE34210.1 - 0.16 12.4 0.4 14 6.2 0.2 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 EPE34210.1 - 0.54 10.4 3.7 2 8.6 0.6 3.0 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 EPE34210.1 - 2.1 7.6 20.3 0.54 9.6 8.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cortex-I_coil PF09304.10 EPE34210.1 - 2.7 8.2 30.1 0.096 12.9 2.6 4.2 3 1 0 4 4 4 0 Cortexillin I, coiled coil Acyltransferase PF01553.21 EPE34211.1 - 7.5e-05 22.4 0.0 0.00026 20.6 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase Tyrosinase PF00264.20 EPE34212.1 - 7.3e-53 180.1 0.3 1.1e-52 179.5 0.1 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase HET PF06985.11 EPE34213.1 - 3.9e-11 43.5 9.8 1.9e-10 41.2 2.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ArAE_2_N PF10337.9 EPE34214.1 - 0.12 11.4 0.1 0.34 9.9 0.1 1.7 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal Baculo_PEP_C PF04513.12 EPE34215.1 - 0.025 14.6 0.3 1 9.4 0.0 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Endotoxin_N PF03945.14 EPE34215.1 - 0.1 12.3 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain DUF2205 PF10224.9 EPE34215.1 - 0.16 12.0 7.4 0.58 10.2 7.4 1.9 1 0 0 1 1 1 0 Short coiled-coil protein ApoLp-III PF07464.11 EPE34215.1 - 2.9 8.0 13.5 9.9 6.3 5.1 2.6 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF5082 PF16888.5 EPE34215.1 - 6.7 7.0 23.5 0.012 15.9 4.4 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF5082) DUF4942 PF13708.6 EPE34216.1 - 0.079 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4942) DUF4448 PF14610.6 EPE34217.1 - 0.00098 18.9 0.4 0.0012 18.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) AChE_tetra PF08674.10 EPE34217.1 - 0.052 13.3 0.6 0.12 12.1 0.6 1.5 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain DUF4202 PF13875.6 EPE34218.1 - 1 9.2 4.3 16 5.3 1.9 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4202) zf-C2H2_4 PF13894.6 EPE34220.1 - 3.3 8.8 6.1 0.88 10.6 0.1 3.0 2 1 0 2 2 2 0 C2H2-type zinc finger G-alpha PF00503.20 EPE34221.1 - 3.1e-80 270.0 0.0 1.3e-79 267.9 0.0 1.8 2 0 0 2 2 2 1 G-protein alpha subunit Arf PF00025.21 EPE34221.1 - 6.2e-07 29.0 0.1 7.9e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPE34221.1 - 0.0002 21.4 0.1 0.012 15.7 0.1 2.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Helo_like_N PF17111.5 EPE34221.1 - 0.0055 16.1 1.0 0.0096 15.3 1.0 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Gtr1_RagA PF04670.12 EPE34221.1 - 0.047 13.0 5.4 0.31 10.4 0.0 3.7 4 0 0 4 4 4 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EPE34221.1 - 0.098 12.4 0.1 3.1 7.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gln-synt_C PF00120.24 EPE34222.1 - 6.9e-11 41.7 0.0 9.2e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain SpoU_methylase PF00588.19 EPE34223.1 - 6.3e-27 94.5 0.0 1.1e-26 93.7 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EPE34223.1 - 2e-05 24.8 0.0 4.7e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding T4BSS_DotH_IcmK PF12293.8 EPE34225.1 - 0.069 12.4 0.0 0.084 12.1 0.0 1.1 1 0 0 1 1 1 0 Putative outer membrane core complex of type IVb secretion WIF PF02019.18 EPE34229.1 - 0.052 13.2 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 WIF domain DUF3557 PF12078.8 EPE34230.1 - 0.19 11.7 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) DDE_3 PF13358.6 EPE34232.1 - 2.7e-27 95.3 0.0 4.5e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.19 EPE34232.1 - 2.6e-06 27.2 0.0 3.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.26 EPE34232.1 - 0.00015 21.9 0.0 0.00026 21.2 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_33 PF13592.6 EPE34232.1 - 0.003 17.2 0.6 0.0068 16.0 0.2 1.8 2 0 0 2 2 2 1 Winged helix-turn helix CSF-1 PF05337.11 EPE34232.1 - 0.051 13.7 0.1 0.075 13.1 0.1 1.2 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) Styelin PF17562.2 EPE34232.1 - 0.51 10.7 2.5 10 6.6 0.1 3.2 4 0 0 4 4 4 0 Styelin TPR_12 PF13424.6 EPE34234.1 - 2e-25 88.9 1.7 3.1e-14 53.0 0.3 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EPE34234.1 - 1.9e-22 78.4 0.8 2.9e-14 52.4 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat Patatin PF01734.22 EPE34234.1 - 1.5e-21 77.5 0.0 3.7e-21 76.2 0.0 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase NB-ARC PF00931.22 EPE34234.1 - 5.2e-12 45.5 0.0 8.9e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_1 PF00515.28 EPE34234.1 - 3.7e-06 26.5 3.1 0.00019 21.1 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EPE34234.1 - 1.6e-05 24.6 2.6 0.00068 19.5 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EPE34234.1 - 4.6e-05 23.5 0.7 0.3 11.6 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPE34234.1 - 0.00058 19.8 0.2 0.016 15.3 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EPE34234.1 - 0.0026 17.8 0.3 0.063 13.5 0.1 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat AAA_16 PF13191.6 EPE34234.1 - 0.0066 16.9 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TPR_4 PF07721.14 EPE34234.1 - 0.016 15.8 0.0 0.78 10.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EPE34234.1 - 0.039 14.6 0.0 0.37 11.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EPE34234.1 - 0.11 12.6 0.0 0.37 10.9 0.0 1.9 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 EPE34234.1 - 0.26 12.2 1.7 4.3 8.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat NmrA PF05368.13 EPE34236.1 - 1.4e-27 96.7 0.8 1.9e-27 96.3 0.8 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE34236.1 - 8.1e-24 84.5 0.0 1.2e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EPE34236.1 - 1.5e-05 25.3 0.4 3.6e-05 24.0 0.1 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EPE34236.1 - 0.00066 19.2 0.0 0.0035 16.8 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE34236.1 - 0.00082 18.5 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 EPE34236.1 - 0.011 15.8 0.7 0.027 14.6 0.1 2.0 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF1353 PF07087.11 EPE34236.1 - 0.15 11.8 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) THF_DHG_CYH_C PF02882.19 EPE34236.1 - 0.3 10.4 1.8 1.9 7.8 1.0 2.4 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Zn_clus PF00172.18 EPE34237.1 - 3.5e-10 39.8 12.3 3.5e-10 39.8 12.3 2.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE34237.1 - 3.2e-08 32.9 0.7 8e-07 28.3 0.6 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPE34237.1 - 1.9e-07 31.2 15.5 0.0016 18.8 2.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE34237.1 - 0.0015 19.2 21.2 0.0028 18.4 1.0 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EPE34237.1 - 0.013 15.7 2.3 0.044 14.1 2.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-met PF12874.7 EPE34237.1 - 0.017 15.5 4.1 0.31 11.5 0.7 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EPE34237.1 - 0.031 14.3 3.9 0.059 13.4 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger FAM24 PF15193.6 EPE34237.1 - 0.77 10.6 4.5 1.3 9.8 1.4 2.6 2 0 0 2 2 2 0 FAM24 family Nop10p PF04135.12 EPE34239.1 - 4.7e-20 71.4 0.9 9.4e-20 70.4 0.9 1.5 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Ank_4 PF13637.6 EPE34239.1 - 5.4e-05 23.7 1.9 7 7.4 0.0 5.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EPE34239.1 - 0.0012 19.2 0.2 4.9 7.8 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeat NOB1_Zn_bind PF08772.11 EPE34240.1 - 8.9e-33 112.3 2.7 1.5e-32 111.6 2.7 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 EPE34240.1 - 1.8e-29 102.0 0.1 6.8e-29 100.2 0.0 2.0 2 0 0 2 2 2 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 EPE34240.1 - 0.076 12.7 1.8 0.48 10.1 0.2 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Rhodanese_C PF12368.8 EPE34240.1 - 0.11 12.9 1.1 0.2 12.1 1.1 1.3 1 0 0 1 1 1 0 Rhodanase C-terminal Ank_2 PF12796.7 EPE34242.1 - 4.7e-05 23.9 0.0 0.00044 20.8 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EPE34242.1 - 0.001 19.4 0.0 0.16 12.5 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EPE34242.1 - 0.0012 19.4 0.0 3.3 8.4 0.0 3.3 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE34242.1 - 0.0016 18.7 0.1 2.3 8.6 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE34242.1 - 0.019 15.5 0.9 7.8 7.4 0.1 4.5 4 1 0 4 4 4 0 Ankyrin repeat Cornifin PF02389.15 EPE34244.1 - 0.014 15.6 0.3 0.023 14.9 0.3 1.3 1 1 0 1 1 1 0 Cornifin (SPRR) family Fungal_trans PF04082.18 EPE34245.1 - 4.7e-09 35.7 5.5 7.2e-09 35.1 5.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HRG PF16954.5 EPE34245.1 - 0.099 13.1 0.2 20 5.7 0.0 3.1 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Glyco_hydro_32N PF00251.20 EPE34246.1 - 2.2e-64 217.9 0.2 3.7e-64 217.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EPE34246.1 - 6.1e-22 78.3 0.3 9.9e-22 77.6 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Bac_rhamnosid6H PF17389.2 EPE34247.1 - 1.2e-10 41.2 0.6 3.7e-10 39.6 0.3 1.7 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 EPE34247.1 - 0.00073 19.3 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Trehalase PF01204.18 EPE34247.1 - 0.006 15.5 0.1 0.0085 15.0 0.1 1.1 1 0 0 1 1 1 1 Trehalase DM13 PF10517.9 EPE34248.1 - 5.7e-12 46.1 0.0 8.6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Electron transfer DM13 NAD_binding_6 PF08030.12 EPE34249.1 - 1.7e-20 73.7 0.2 4e-20 72.5 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EPE34249.1 - 6.9e-20 71.4 12.9 6.9e-20 71.4 12.9 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EPE34249.1 - 1.2e-13 51.0 0.0 2.5e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EPE34249.1 - 0.027 15.1 0.0 0.55 10.9 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain p450 PF00067.22 EPE34250.1 - 7.2e-63 212.9 0.0 9e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GA-like PF17573.2 EPE34250.1 - 0.12 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 GA-like domain Podoplanin PF05808.11 EPE34252.1 - 0.005 17.0 3.5 0.0071 16.5 3.5 1.2 1 0 0 1 1 1 1 Podoplanin DUF5305 PF17231.2 EPE34252.1 - 0.0077 15.7 1.2 0.01 15.2 1.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5305) SKG6 PF08693.10 EPE34252.1 - 0.026 13.9 0.6 0.071 12.5 0.6 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Vpu PF00558.19 EPE34252.1 - 0.2 11.5 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Vpu protein FSA_C PF10479.9 EPE34252.1 - 3.8 5.5 9.8 4.4 5.3 9.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SSP160 PF06933.11 EPE34252.1 - 5 5.2 23.0 6.4 4.9 23.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CBAH PF02275.18 EPE34253.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 2 0 0 2 2 2 0 Linear amide C-N hydrolases, choloylglycine hydrolase family Exo_endo_phos PF03372.23 EPE34253.1 - 0.17 11.4 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Class_IIIsignal PF04021.12 EPE34254.1 - 8.1 6.6 14.1 0.43 10.6 2.3 2.6 2 0 0 2 2 2 0 Class III signal peptide Sh_2 PF17512.2 EPE34255.1 - 7e-05 22.7 0.7 0.0001 22.2 0.7 1.3 1 0 0 1 1 1 1 Metapneumovirus Small hydrophobic protein Adap_comp_sub PF00928.21 EPE34256.1 - 2.8e-92 308.8 0.0 5.8e-92 307.8 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EPE34256.1 - 2.3e-09 37.3 0.2 3.9e-09 36.6 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EPE34256.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.5 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Opi1 PF08618.10 EPE34257.1 - 5.3e-45 154.4 11.1 3.2e-34 118.9 2.7 3.2 2 1 1 3 3 3 3 Transcription factor Opi1 VCPO_N PF17897.1 EPE34258.1 - 9.8e-98 326.2 0.8 1.3e-97 325.8 0.8 1.2 1 0 0 1 1 1 1 Vanadium chloroperoxidase N-terminal domain PAP2 PF01569.21 EPE34258.1 - 9.5e-12 44.9 0.5 3.8e-11 42.9 0.5 1.9 1 1 0 1 1 1 1 PAP2 superfamily DnaJ PF00226.31 EPE34259.1 - 6.6e-11 42.2 0.2 1.9e-10 40.7 0.2 1.8 1 1 0 1 1 1 1 DnaJ domain zf-HIT PF04438.16 EPE34259.1 - 1.7 8.6 7.0 0.41 10.6 3.2 1.9 2 0 0 2 2 2 0 HIT zinc finger Ribonucleas_3_3 PF14622.6 EPE34260.1 - 2.4e-06 27.8 0.0 4.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EPE34260.1 - 0.028 15.1 0.1 0.3 11.7 0.0 2.7 2 1 0 2 2 2 0 Ribonuclease III domain DUF3638 PF12340.8 EPE34261.1 - 1.2e-84 283.2 0.5 1.4e-61 207.7 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EPE34261.1 - 1.4e-15 56.4 0.2 3.1e-15 55.2 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) OTT_1508_deam PF14441.6 EPE34262.1 - 1.8e-19 69.5 0.0 3.9e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Dynamin_N PF00350.23 EPE34263.1 - 2e-30 106.1 0.0 3.6e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EPE34263.1 - 2.5e-27 95.9 0.0 3.7e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EPE34263.1 - 0.0014 18.7 0.1 0.037 14.1 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase UPRTase PF14681.6 EPE34264.1 - 7.8e-40 136.5 0.2 1.4e-39 135.7 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.6 EPE34264.1 - 3e-24 86.0 0.0 6.6e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain HAD PF12710.7 EPE34264.1 - 6e-21 75.7 0.3 1.3e-20 74.6 0.1 1.8 2 0 0 2 2 1 1 haloacid dehalogenase-like hydrolase Pribosyltran PF00156.27 EPE34264.1 - 8.9e-05 22.1 0.9 0.0025 17.3 0.9 2.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain KAP_NTPase PF07693.14 EPE34264.1 - 0.00013 21.3 0.0 0.00023 20.5 0.0 1.5 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.6 EPE34264.1 - 0.00023 21.6 0.0 0.00093 19.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EPE34264.1 - 0.0005 20.2 0.1 0.0038 17.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EPE34264.1 - 0.0021 17.3 0.0 0.009 15.3 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 EPE34264.1 - 0.0035 17.9 0.0 0.012 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain PRTase_2 PF15609.6 EPE34264.1 - 0.0048 16.4 0.2 0.015 14.8 0.1 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase Hydrolase PF00702.26 EPE34264.1 - 0.011 16.1 0.1 0.016 15.5 0.1 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase AAA PF00004.29 EPE34264.1 - 0.019 15.4 0.0 0.046 14.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 EPE34264.1 - 0.019 15.0 0.0 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Torsin AAA_30 PF13604.6 EPE34264.1 - 0.02 14.6 0.3 0.7 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EPE34264.1 - 0.036 14.3 0.1 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EPE34264.1 - 0.097 12.6 0.1 0.33 10.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 EPE34264.1 - 0.13 11.4 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Hydrolase_3 PF08282.12 EPE34264.1 - 0.15 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AAA_24 PF13479.6 EPE34264.1 - 0.25 11.0 0.7 0.6 9.8 0.0 2.0 3 0 0 3 3 3 0 AAA domain HET PF06985.11 EPE34265.1 - 1.3e-06 28.8 0.0 2.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ifi-6-16 PF06140.13 EPE34266.1 - 0.029 14.3 13.4 0.051 13.5 13.4 1.3 1 0 0 1 1 1 0 Interferon-induced 6-16 family DHR10 PF18595.1 EPE34268.1 - 0.0015 18.6 3.4 0.077 13.1 0.5 2.4 2 0 0 2 2 2 2 Designed helical repeat protein 10 domain NleF_casp_inhib PF16809.5 EPE34268.1 - 0.056 13.4 0.2 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 NleF caspase inhibitor Uds1 PF15456.6 EPE34268.1 - 0.071 13.3 1.5 0.14 12.4 1.5 1.5 1 0 0 1 1 1 0 Up-regulated During Septation DUF2390 PF09523.10 EPE34268.1 - 0.097 13.0 0.4 0.097 13.0 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2390) eIF3_subunit PF08597.10 EPE34268.1 - 0.15 11.9 0.2 0.18 11.7 0.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4618 PF15397.6 EPE34268.1 - 0.22 10.9 1.6 0.2 11.1 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) HrpB2 PF09487.10 EPE34268.1 - 0.54 10.7 3.6 0.59 10.6 0.6 2.3 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB2) HalX PF08663.10 EPE34268.1 - 1 9.7 4.9 1.7 9.0 0.9 2.7 3 0 0 3 3 3 0 HalX domain DUF3684 PF12449.8 EPE34269.1 - 0.025 12.4 0.1 0.034 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) Melibiase_2 PF16499.5 EPE34270.1 - 6.7e-56 189.5 6.5 5.1e-39 134.2 0.6 2.3 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 EPE34270.1 - 1.4e-10 41.1 0.5 8.2e-09 35.4 0.0 2.8 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EPE34270.1 - 1.9e-07 30.3 0.0 3.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Melibiase Raffinose_syn PF05691.12 EPE34270.1 - 0.012 13.5 0.4 0.017 13.0 0.4 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_26 PF02156.15 EPE34271.1 - 2.1e-61 208.1 6.8 2.2e-61 208.0 5.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_1 PF00734.18 EPE34271.1 - 3.4e-11 42.9 10.6 9.6e-11 41.5 10.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.6 EPE34272.1 - 2.2e-18 67.3 0.1 2.8e-18 66.9 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE34272.1 - 6.6e-08 32.8 0.0 1.2e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 EPE34272.1 - 3.4e-05 23.2 0.0 4.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 OSK domain Lipase_GDSL_3 PF14606.6 EPE34272.1 - 0.0035 17.5 0.0 0.0048 17.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Coiled PF05710.12 EPE34272.1 - 0.67 10.8 5.0 2.3 9.1 0.2 2.5 2 0 0 2 2 2 0 Coiled coil Glyco_hydro_61 PF03443.14 EPE34273.1 - 1.5e-36 126.2 2.3 9.6e-18 64.9 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 Glyco_hydro_127 PF07944.12 EPE34274.1 - 3.1e-20 72.2 0.8 7.1e-17 61.1 0.1 2.4 2 1 1 3 3 3 2 Beta-L-arabinofuranosidase, GH127 Alginate_lyase PF05426.12 EPE34275.1 - 2e-07 30.8 7.4 5.3e-07 29.5 7.4 1.6 1 1 0 1 1 1 1 Alginate lyase Aldo_ket_red PF00248.21 EPE34276.1 - 1.5e-52 178.6 0.0 2.1e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 EPE34277.1 - 6.6e-30 104.2 33.9 7.1e-30 104.1 33.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EPE34277.1 - 2.5e-09 36.9 7.6 2.5e-09 36.9 7.6 2.7 2 1 2 4 4 4 1 Uncharacterised MFS-type transporter YbfB 2TM PF13239.6 EPE34277.1 - 0.56 10.5 0.1 0.56 10.5 0.1 4.3 3 1 0 3 3 3 0 2TM domain Fungal_trans PF04082.18 EPE34278.1 - 9.4e-20 70.7 0.1 2e-19 69.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE34278.1 - 5.7e-07 29.6 14.4 1.1e-06 28.7 14.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5382 PF17354.2 EPE34278.1 - 0.035 13.0 0.0 0.069 12.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5382) NFACT-R_2 PF18297.1 EPE34278.1 - 0.2 11.9 0.1 37 4.6 0.0 2.5 2 0 0 2 2 2 0 NFACT protein RNA binding domain Glyco_hydro_88 PF07470.13 EPE34279.1 - 3.2e-13 49.5 0.6 4.9e-13 48.9 0.6 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Zn_clus PF00172.18 EPE34280.1 - 5.6e-07 29.6 8.7 1.4e-06 28.3 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 EPE34281.1 - 1.2e-10 41.4 0.0 1.7e-10 40.9 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE34281.1 - 1.4e-08 34.9 0.0 3.9e-08 33.4 0.0 1.7 3 0 0 3 3 3 1 NAD(P)H-binding DapB_N PF01113.20 EPE34281.1 - 0.00057 20.0 0.0 0.0011 19.0 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EPE34281.1 - 0.0006 20.2 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EPE34281.1 - 0.0014 18.1 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EPE34281.1 - 0.035 13.2 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 EPE34281.1 - 0.12 11.5 0.2 15 4.6 0.0 2.4 3 0 0 3 3 3 0 Male sterility protein 3Beta_HSD PF01073.19 EPE34281.1 - 0.13 11.2 0.0 0.43 9.5 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 EPE34281.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pkinase PF00069.25 EPE34282.1 - 5.8e-15 55.4 0.0 8.7e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 EPE34282.1 - 0.0025 17.4 0.0 0.0058 16.2 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EPE34282.1 - 0.018 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EPE34282.1 - 0.023 14.1 0.0 0.058 12.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TRI12 PF06609.13 EPE34286.1 - 9.5e-27 93.7 28.9 1.2e-26 93.3 28.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EPE34286.1 - 3.8e-23 82.0 49.8 5.5e-22 78.2 42.1 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.19 EPE34287.1 - 3.2e-18 66.1 0.0 9.2e-18 64.6 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EPE34287.1 - 1.2e-06 28.1 0.0 0.0071 15.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPE34287.1 - 1.7e-06 28.1 0.2 3.9e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE34287.1 - 5.8e-06 25.8 0.3 0.00012 21.4 0.2 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE34287.1 - 4.1e-05 23.3 0.1 0.00013 21.7 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPE34287.1 - 8.5e-05 21.8 0.2 0.00013 21.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EPE34287.1 - 0.00026 20.4 0.2 0.0004 19.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EPE34287.1 - 0.00098 19.6 0.1 0.0043 17.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE34287.1 - 0.0012 17.6 0.7 0.0032 16.2 0.3 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 EPE34287.1 - 0.0075 16.3 0.1 0.32 11.0 0.0 2.6 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 EPE34287.1 - 0.0081 15.4 0.1 0.015 14.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 EPE34287.1 - 0.009 14.9 0.0 1.8 7.3 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 EPE34287.1 - 0.012 14.7 0.1 0.018 14.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 EPE34287.1 - 0.058 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 EPE34287.1 - 0.068 12.4 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EPE34287.1 - 0.087 12.1 0.2 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Collagen PF01391.18 EPE34288.1 - 3.3e-37 126.0 153.5 6.5e-09 35.4 24.3 5.4 2 1 3 5 5 5 5 Collagen triple helix repeat (20 copies) WSC PF01822.19 EPE34288.1 - 0.021 15.0 0.2 0.036 14.2 0.2 1.3 1 0 0 1 1 1 0 WSC domain Lactamase_B_6 PF16661.5 EPE34289.1 - 1.8e-64 216.8 0.0 3.5e-64 215.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EPE34289.1 - 3.9e-49 167.1 1.5 7.1e-49 166.3 0.0 2.1 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EPE34289.1 - 1.1e-18 67.5 0.0 9.2e-18 64.6 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 EPE34289.1 - 3.3e-11 42.9 0.0 7.3e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain ANAPC_CDC26 PF10471.9 EPE34289.1 - 0.034 15.0 2.9 0.12 13.3 2.9 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Sec23_trunk PF04811.15 EPE34290.1 - 2.9e-53 181.0 0.0 6.6e-53 179.8 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EPE34290.1 - 1.6e-24 85.7 0.0 3e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EPE34290.1 - 6.2e-18 65.3 0.0 1e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EPE34290.1 - 1.5e-14 53.7 9.2 3.4e-14 52.6 9.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EPE34290.1 - 6.1e-08 32.5 0.0 1.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat SUR7 PF06687.12 EPE34291.1 - 9.5e-08 31.9 4.4 1.3e-07 31.4 4.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family MFS_1 PF07690.16 EPE34292.1 - 3.3e-22 78.9 40.3 4.2e-22 78.5 40.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF485 PF04341.12 EPE34292.1 - 2.1 8.4 6.4 4.8 7.2 3.8 2.8 1 1 1 2 2 2 0 Protein of unknown function, DUF485 Beta-lactamase2 PF13354.6 EPE34293.1 - 0.22 11.1 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase enzyme family Zn_clus PF00172.18 EPE34294.1 - 2.2e-07 30.9 10.9 3.6e-07 30.2 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE34294.1 - 8.4e-05 21.7 0.0 0.00017 20.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3802 PF12290.8 EPE34294.1 - 0.0095 16.4 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3802) MFS_1 PF07690.16 EPE34295.1 - 3.3e-32 111.8 25.1 4.9e-32 111.2 25.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MASE2 PF05230.11 EPE34295.1 - 0.0079 16.2 3.4 0.65 10.1 1.2 2.9 2 0 0 2 2 2 2 MASE2 domain DUF3948 PF13134.6 EPE34295.1 - 0.04 13.6 0.2 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) LapA_dom PF06305.11 EPE34295.1 - 2 8.3 6.1 3 7.7 0.2 3.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Cu_amine_oxid PF01179.20 EPE34296.1 - 2.9e-166 553.4 0.1 3.8e-166 553.1 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 EPE34296.1 - 2.9e-11 43.5 0.1 6.5e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain TMEM234 PF10639.9 EPE34296.1 - 0.22 11.6 0.0 0.42 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative transmembrane family 234 DUF1857 PF08982.11 EPE34297.1 - 7.6e-51 171.8 0.2 8.8e-51 171.6 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Zn_clus PF00172.18 EPE34298.1 - 1.8e-07 31.2 13.5 1.8e-07 31.2 13.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE34298.1 - 0.13 11.3 1.4 0.12 11.3 0.1 1.5 2 0 0 2 2 2 0 Fungal specific transcription factor domain Spt4 PF06093.13 EPE34298.1 - 0.34 11.0 4.3 0.93 9.6 2.4 2.3 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger DUF4535 PF15054.6 EPE34299.1 - 0.7 9.7 2.4 2 8.2 2.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) MFS_1 PF07690.16 EPE34300.1 - 1.8e-31 109.3 28.5 2.8e-31 108.7 28.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ICL PF00463.21 EPE34301.1 - 7.1e-119 397.7 0.0 8.8e-119 397.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family DUF2935 PF11155.8 EPE34301.1 - 0.13 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Aminotran_1_2 PF00155.21 EPE34302.1 - 5.6e-17 61.9 0.0 8.4e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II P22_AR_C PF10548.9 EPE34302.1 - 0.11 12.6 0.4 0.65 10.2 0.1 2.2 2 0 0 2 2 2 0 P22AR C-terminal domain Hydantoinase_B PF02538.14 EPE34303.1 - 1.7e-197 656.9 0.8 2.2e-197 656.6 0.8 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EPE34303.1 - 1.9e-101 339.2 0.1 1.9e-101 339.2 0.1 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EPE34303.1 - 1.6e-55 187.6 0.3 3.2e-54 183.3 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.16 EPE34305.1 - 4.9e-17 61.9 65.1 3.2e-15 55.9 62.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE34305.1 - 1.6e-07 30.2 28.2 2.2e-07 29.7 28.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Antimicrobial24 PF16049.5 EPE34305.1 - 4.9 7.2 5.8 0.63 10.1 0.6 2.2 2 0 0 2 2 2 0 Frog antimicrobial peptide CFEM PF05730.11 EPE34306.1 - 3.9e-08 33.3 3.1 1.1e-07 31.8 3.1 1.8 1 1 0 1 1 1 1 CFEM domain Med3 PF11593.8 EPE34306.1 - 1.3 8.1 9.6 1.5 7.9 9.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FSA_C PF10479.9 EPE34306.1 - 1.6 6.8 9.1 1.8 6.6 9.1 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SprA-related PF12118.8 EPE34306.1 - 2.2 7.3 11.3 3 6.9 11.3 1.1 1 0 0 1 1 1 0 SprA-related family Pyr_redox_2 PF07992.14 EPE34307.1 - 1.3e-35 123.1 0.1 1.8e-35 122.6 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE34307.1 - 6e-10 39.6 1.9 3.1e-09 37.3 1.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE34307.1 - 4.3e-05 22.9 0.0 0.00011 21.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE34307.1 - 6.4e-05 22.2 0.5 0.1 11.6 0.2 3.4 4 0 0 4 4 4 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EPE34307.1 - 0.00082 18.3 0.5 3.5 6.4 0.1 3.1 2 1 1 3 3 3 2 Tryptophan halogenase HI0933_like PF03486.14 EPE34307.1 - 0.0015 17.4 0.5 0.22 10.2 0.1 3.6 4 0 0 4 4 4 1 HI0933-like protein NAD_binding_9 PF13454.6 EPE34307.1 - 0.0036 17.3 2.0 2.2 8.2 0.0 4.2 4 1 0 5 5 5 1 FAD-NAD(P)-binding DAO PF01266.24 EPE34307.1 - 0.0039 16.8 0.2 3.9 6.9 0.1 3.2 3 1 1 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 EPE34307.1 - 0.0056 15.9 0.0 0.012 14.8 0.1 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EPE34307.1 - 0.0096 16.1 0.0 2.9 8.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE34307.1 - 0.013 14.6 0.2 0.19 10.8 0.3 2.6 3 0 0 3 3 3 0 FAD binding domain Optomotor-blind PF11078.8 EPE34307.1 - 0.044 14.3 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region Thi4 PF01946.17 EPE34307.1 - 0.081 12.2 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 EPE34307.1 - 0.36 9.8 3.7 1.1 8.3 0.2 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A Acetyltransf_1 PF00583.25 EPE34308.1 - 4e-07 30.3 0.1 1.1e-06 28.9 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE34308.1 - 6.9e-06 26.0 0.0 1.4e-05 25.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE34308.1 - 0.00011 22.5 0.0 0.00026 21.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPE34308.1 - 0.0048 17.0 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Hva1_TUDOR PF11160.8 EPE34310.1 - 1.2e-15 57.4 2.5 1.6e-15 57.0 2.5 1.2 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Thioredoxin_2 PF13098.6 EPE34310.1 - 0.049 14.1 0.0 0.053 14.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain VipB PF05943.12 EPE34310.1 - 0.13 11.0 0.1 0.16 10.7 0.1 1.0 1 0 0 1 1 1 0 Type VI secretion protein, EvpB/VC_A0108, tail sheath Gti1_Pac2 PF09729.9 EPE34314.1 - 1.7e-42 145.6 8.4 4.9e-36 124.5 0.1 3.1 2 1 1 3 3 3 2 Gti1/Pac2 family tRNA-synt_2 PF00152.20 EPE34315.1 - 3e-80 269.6 0.0 3.7e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EPE34315.1 - 3.6e-07 30.1 0.0 5.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2263 PF10021.9 EPE34316.1 - 7.9e-15 55.5 0.0 1.3e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) RAP1 PF07218.11 EPE34316.1 - 1.2 7.4 7.5 1.5 7.0 7.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HET PF06985.11 EPE34317.1 - 2.8e-34 118.6 2.5 4.8e-34 117.8 2.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.7 EPE34318.1 - 1e-20 74.1 2.1 1.2e-09 38.6 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE34318.1 - 3e-17 62.4 6.0 6e-07 29.6 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE34318.1 - 7.5e-15 53.6 5.0 0.0012 19.2 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EPE34318.1 - 1.8e-12 47.5 4.2 3.9e-05 24.1 0.2 4.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EPE34318.1 - 4.1e-12 46.0 11.5 2.9e-05 24.3 0.3 4.4 4 0 0 4 4 4 2 Ankyrin repeat CorA PF01544.18 EPE34320.1 - 1.8e-10 40.6 0.1 2.7e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4233 PF14017.6 EPE34320.1 - 0.0056 17.0 0.4 0.009 16.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4233) Far-17a_AIG1 PF04750.14 EPE34320.1 - 0.023 14.0 0.4 0.04 13.2 0.4 1.3 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein WD40 PF00400.32 EPE34321.1 - 4e-13 49.6 1.0 1.6e-06 28.7 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE34321.1 - 0.00048 20.4 0.0 0.00086 19.6 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain EMG1 PF03587.14 EPE34322.1 - 4.9e-78 261.2 0.1 5.7e-78 261.0 0.1 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase RP854 PF17460.2 EPE34322.1 - 0.055 13.2 0.2 0.089 12.5 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein RP854 Plk4_PB2 PF18409.1 EPE34322.1 - 0.079 13.7 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 Gly-zipper_Omp PF13488.6 EPE34323.1 - 0.005 16.8 2.0 0.005 16.8 2.0 2.2 2 0 0 2 2 2 1 Glycine zipper Rick_17kDa_Anti PF05433.15 EPE34323.1 - 0.19 11.6 12.9 0.88 9.5 12.9 2.2 1 1 0 1 1 1 0 Glycine zipper 2TM domain 4HBT_3 PF13622.6 EPE34324.1 - 9.9e-44 150.4 0.0 1.1e-43 150.2 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily HET PF06985.11 EPE34326.1 - 9.3e-31 107.1 7.0 9.3e-31 107.1 7.0 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) LCAT PF02450.15 EPE34327.1 - 2.5e-102 343.0 0.0 3e-102 342.7 0.0 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.18 EPE34327.1 - 0.76 9.3 3.2 0.55 9.7 0.0 2.3 4 0 0 4 4 4 0 Lipase (class 2) SKG6 PF08693.10 EPE34328.1 - 0.0028 17.0 0.2 0.0028 17.0 0.2 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4718 PF15842.5 EPE34328.1 - 0.028 14.2 4.7 3.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) Mid2 PF04478.12 EPE34328.1 - 0.14 12.0 1.6 0.55 10.1 1.6 1.9 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor VSP PF03302.13 EPE34328.1 - 1.8 7.4 7.3 3.1 6.6 2.0 2.1 1 1 1 2 2 2 0 Giardia variant-specific surface protein SesA PF17107.5 EPE34329.1 - 0.028 14.6 0.1 0.2 11.9 0.1 2.3 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases VIT PF08487.10 EPE34330.1 - 1.5e-30 105.7 0.0 2.8e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EPE34330.1 - 2.5e-26 92.5 0.0 1.3e-25 90.1 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 EPE34330.1 - 1.7e-08 34.3 0.0 3.3e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 EPE34330.1 - 5.2e-08 33.3 0.0 9.8e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EPE34330.1 - 3.5e-06 27.6 0.0 7.9e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EPE34330.1 - 0.00011 21.7 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein AA_permease_2 PF13520.6 EPE34332.1 - 4.5e-57 193.8 51.0 5.6e-57 193.5 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE34332.1 - 6.8e-17 61.2 40.1 1.1e-16 60.5 40.1 1.2 1 0 0 1 1 1 1 Amino acid permease MerE PF05052.12 EPE34332.1 - 0.016 15.1 0.4 0.016 15.1 0.4 3.4 4 0 0 4 4 4 0 MerE protein CRPA PF05745.11 EPE34332.1 - 2.1 8.3 5.8 0.99 9.4 0.7 2.7 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF3040 PF11239.8 EPE34332.1 - 3.7 7.9 8.1 2.1 8.7 0.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3040) DUF973 PF06157.11 EPE34332.1 - 5.5 6.0 9.0 0.49 9.4 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF973) DUF2434 PF10361.9 EPE34333.1 - 1.7e-138 460.5 2.7 2.4e-138 460.0 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) COG5 PF10392.9 EPE34334.1 - 8.7e-41 139.2 0.2 8.7e-41 139.2 0.2 2.2 2 0 0 2 2 2 1 Golgi transport complex subunit 5 RCS1 PF07326.11 EPE34334.1 - 0.21 11.5 4.1 0.45 10.4 4.1 1.5 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 La PF05383.17 EPE34335.1 - 2.2e-10 40.4 0.0 5.2e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 La domain p450 PF00067.22 EPE34336.1 - 4.8e-38 131.1 0.0 6.3e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF569 PF04601.13 EPE34336.1 - 0.098 12.3 0.0 19 4.9 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF569) p450 PF00067.22 EPE34337.1 - 1.3e-34 119.8 0.0 1.8e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Thioesterase PF00975.20 EPE34338.1 - 2.5e-19 70.3 0.0 3.4e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EPE34338.1 - 6.8e-08 33.4 0.0 8e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EPE34338.1 - 0.00031 20.6 0.0 0.00051 19.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2974 PF11187.8 EPE34338.1 - 0.00042 20.0 0.0 0.00085 18.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 EPE34338.1 - 0.00072 19.3 0.2 0.0012 18.6 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EPE34338.1 - 0.00075 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE34338.1 - 0.0083 15.4 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EPE34338.1 - 0.036 13.8 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cutinase PF01083.22 EPE34338.1 - 0.064 13.2 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 Cutinase 2OG-FeII_Oxy PF03171.20 EPE34339.1 - 1.3e-15 57.7 0.0 2.3e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EPE34339.1 - 0.0064 17.2 0.1 0.014 16.2 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PS-DH PF14765.6 EPE34340.1 - 2.6e-62 210.8 0.0 3.7e-62 210.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.26 EPE34340.1 - 1.1e-61 208.6 0.6 5.6e-61 206.3 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EPE34340.1 - 4e-60 202.8 0.0 8.6e-60 201.7 0.0 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EPE34340.1 - 1.7e-58 198.6 0.0 2.8e-58 197.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE34340.1 - 6.9e-36 122.9 0.1 2.1e-35 121.3 0.1 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EPE34340.1 - 7.8e-19 68.3 0.0 2.2e-18 66.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EPE34340.1 - 1.4e-18 67.3 10.0 2.1e-14 53.9 0.9 2.6 1 1 1 2 2 2 2 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 EPE34340.1 - 6.9e-17 61.6 0.1 2.3e-16 59.9 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE34340.1 - 1.5e-16 61.7 0.0 1.6e-15 58.3 0.0 2.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EPE34340.1 - 1.3e-11 44.7 0.0 2.7e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EPE34340.1 - 7.2e-09 35.4 0.0 4.1e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_25 PF13649.6 EPE34340.1 - 1.3e-08 35.5 0.0 4.9e-08 33.6 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE34340.1 - 2.2e-08 34.0 0.0 8.1e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE34340.1 - 3.4e-07 30.8 0.0 8.4e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EPE34340.1 - 4.2e-06 27.0 0.1 1.4e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EPE34340.1 - 0.00012 21.9 0.2 0.00045 20.1 0.2 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EPE34340.1 - 0.00065 19.1 0.1 0.00065 19.1 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 EPE34340.1 - 0.014 15.1 0.0 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 Lysine methyltransferase ACP_syn_III PF08545.10 EPE34340.1 - 0.097 12.5 0.3 0.28 11.1 0.3 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ubie_methyltran PF01209.18 EPE34340.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AMP-binding PF00501.28 EPE34341.1 - 0 1444.3 5.4 6.1e-79 265.6 0.1 7.2 6 1 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 EPE34341.1 - 2.2e-274 910.1 0.0 1.9e-45 155.4 0.0 7.8 7 1 0 7 7 7 7 Condensation domain PP-binding PF00550.25 EPE34341.1 - 6.9e-81 266.6 17.4 4.8e-12 46.0 0.1 8.1 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPE34341.1 - 5.4e-10 40.1 0.0 4.1 8.4 0.0 7.2 6 0 0 6 6 6 2 AMP-binding enzyme C-terminal domain FAST_1 PF06743.15 EPE34341.1 - 0.0093 15.9 0.0 6.4 6.8 0.0 5.0 6 0 0 6 6 6 1 FAST kinase-like protein, subdomain 1 KaiB PF07689.12 EPE34341.1 - 0.019 14.7 0.3 42 4.0 0.0 4.3 4 0 0 4 4 4 0 KaiB domain OKR_DC_1_C PF03711.15 EPE34341.1 - 0.032 14.5 0.1 16 5.8 0.0 4.0 4 0 0 4 4 4 0 Orn/Lys/Arg decarboxylase, C-terminal domain RuvB_C PF05491.13 EPE34341.1 - 0.075 12.9 0.4 37 4.3 0.0 3.7 3 0 0 3 3 3 0 RuvB C-terminal winged helix domain AATase PF07247.12 EPE34341.1 - 0.14 10.6 0.2 10 4.6 0.0 2.7 3 0 0 3 3 3 0 Alcohol acetyltransferase ABC_tran PF00005.27 EPE34342.1 - 1.5e-47 161.6 0.1 3.7e-27 95.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPE34342.1 - 4.8e-26 92.0 33.4 4.4e-24 85.6 14.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EPE34342.1 - 2.6e-10 40.1 6.4 0.0014 18.1 0.3 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EPE34342.1 - 3.1e-09 37.1 3.6 0.23 11.2 0.1 4.3 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EPE34342.1 - 3.1e-06 27.2 0.5 0.015 15.2 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EPE34342.1 - 7.2e-06 25.6 3.0 0.036 13.8 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 EPE34342.1 - 2.4e-05 23.5 0.6 0.12 11.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 EPE34342.1 - 5.9e-05 23.4 2.5 0.12 12.6 0.1 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EPE34342.1 - 0.00013 22.4 0.1 0.45 10.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 EPE34342.1 - 0.00019 21.6 0.1 1.3 9.3 0.0 2.9 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EPE34342.1 - 0.00022 21.0 2.2 0.48 10.1 0.2 3.0 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EPE34342.1 - 0.0003 20.9 0.1 0.61 10.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EPE34342.1 - 0.00048 19.6 0.3 0.042 13.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_7 PF12775.7 EPE34342.1 - 0.00084 18.9 0.4 1.1 8.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region Dynamin_N PF00350.23 EPE34342.1 - 0.00092 19.3 0.6 0.44 10.6 0.1 2.6 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 EPE34342.1 - 0.0011 19.1 5.6 0.018 15.1 0.5 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 EPE34342.1 - 0.0066 17.0 3.5 0.9 10.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EPE34342.1 - 0.0067 16.2 1.5 0.13 12.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EPE34342.1 - 0.007 16.5 0.0 0.55 10.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 EPE34342.1 - 0.0082 16.0 0.1 0.82 9.5 0.0 3.0 3 0 0 3 3 3 1 Deoxynucleoside kinase Zeta_toxin PF06414.12 EPE34342.1 - 0.014 14.7 0.8 2.7 7.2 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 EPE34342.1 - 0.018 14.8 1.3 0.53 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EPE34342.1 - 0.022 15.3 0.3 8 7.0 0.2 2.5 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EPE34342.1 - 0.024 13.6 1.3 0.95 8.3 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 EPE34342.1 - 0.035 13.7 2.2 0.21 11.2 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EPE34342.1 - 0.062 13.7 1.8 4.3 7.8 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EPE34342.1 - 0.073 12.6 0.7 5.4 6.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EPE34342.1 - 0.19 11.6 0.3 0.75 9.7 0.1 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EPE34342.1 - 0.23 10.6 2.2 38 3.4 0.3 3.3 3 0 0 3 3 3 0 NB-ARC domain DEAD PF00270.29 EPE34342.1 - 1.5 8.6 5.3 1.4 8.7 1.1 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase Aconitase PF00330.20 EPE34343.1 - 6.4e-70 236.4 0.1 5.3e-68 230.1 0.1 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EPE34343.1 - 1.3e-15 57.9 0.0 2.4e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Iso_dh PF00180.20 EPE34344.1 - 5e-114 381.1 0.0 5.7e-114 380.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HMGL-like PF00682.19 EPE34345.1 - 4.4e-67 226.4 0.0 7e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 HMGL-like Aminotran_4 PF01063.19 EPE34346.1 - 2.5e-19 70.1 0.0 3e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DIOX_N PF14226.6 EPE34347.1 - 3.7e-18 66.4 0.1 6.2e-18 65.7 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPE34347.1 - 1.6e-15 57.4 0.0 3.4e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily KNOX2 PF03791.13 EPE34347.1 - 0.094 12.2 0.1 0.31 10.6 0.1 1.8 1 0 0 1 1 1 0 KNOX2 domain 2OG-FeII_Oxy PF03171.20 EPE34348.1 - 6.8e-12 45.8 0.1 1.3e-11 44.8 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EPE34348.1 - 6.1e-10 39.9 0.0 1.1e-09 39.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal AMP-binding PF00501.28 EPE34349.1 - 2.9e-68 230.4 0.0 3.5e-68 230.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE34349.1 - 5.5e-15 56.1 0.0 1.4e-14 54.8 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DIOX_N PF14226.6 EPE34350.1 - 6.7e-21 75.2 0.1 1.4e-20 74.2 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPE34350.1 - 4.5e-15 56.0 0.0 8.2e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HET PF06985.11 EPE34353.1 - 3.7e-25 89.0 0.2 8.2e-25 87.9 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2 PF00096.26 EPE34356.1 - 1.2e-05 25.5 11.7 0.005 17.2 1.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPE34356.1 - 0.0003 21.1 3.8 0.0003 21.1 3.8 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPE34356.1 - 0.00061 20.4 11.3 0.08 13.8 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EPE34356.1 - 2.4 8.0 6.4 2.3 8.1 0.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Bacillus_HBL PF05791.11 EPE34357.1 - 0.0043 16.9 17.3 0.066 13.0 0.7 4.6 4 0 0 4 4 4 2 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.9 EPE34357.1 - 0.092 12.8 0.2 0.092 12.8 0.2 8.2 5 3 2 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG5 PF10392.9 EPE34357.1 - 0.14 12.4 19.3 0.4 10.9 0.3 4.4 4 0 0 4 4 4 0 Golgi transport complex subunit 5 DUF2935 PF11155.8 EPE34357.1 - 0.98 9.8 6.1 14 6.0 0.0 4.2 4 1 0 5 5 5 0 Domain of unknown function (DUF2935) SPACA9 PF15120.6 EPE34357.1 - 1.4 8.6 6.1 3.6 7.3 0.3 3.4 3 0 0 3 3 3 0 Sperm acrosome-associated protein 9 bZIP_1 PF00170.21 EPE34357.1 - 2 8.6 23.4 5.5 7.2 0.3 7.1 6 1 0 6 6 6 0 bZIP transcription factor Noelin-1 PF12308.8 EPE34357.1 - 3.3 7.8 8.9 1.1 9.2 0.4 4.0 2 1 1 3 3 3 0 Neurogenesis glycoprotein Spc29 PF17082.5 EPE34357.1 - 4.4 7.1 16.1 0.27 11.0 0.2 4.4 2 1 1 3 3 3 0 Spindle Pole Component 29 FlaC_arch PF05377.11 EPE34357.1 - 8.7 6.8 25.2 47 4.5 0.1 8.4 7 1 1 8 8 8 0 Flagella accessory protein C (FlaC) GST_N PF02798.20 EPE34358.1 - 6.7e-14 52.0 0.0 3.8e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPE34358.1 - 2.9e-11 43.6 0.0 5.1e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPE34358.1 - 1.8e-10 40.9 0.0 3.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EPE34358.1 - 2.2e-08 34.2 0.0 4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPE34358.1 - 4.2e-07 30.1 0.0 8.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPE34358.1 - 9.6e-06 25.5 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Helicase_C_2 PF13307.6 EPE34359.1 - 8e-58 195.4 0.0 1.9e-57 194.1 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EPE34359.1 - 7.2e-52 175.5 0.0 1.2e-51 174.8 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EPE34359.1 - 0.019 15.0 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 EPE34359.1 - 0.03 14.1 0.0 3.4 7.4 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_22 PF13401.6 EPE34359.1 - 0.095 13.0 1.1 2.6 8.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain CENP-I PF07778.11 EPE34359.1 - 0.86 8.2 2.6 1.4 7.6 2.6 1.2 1 0 0 1 1 1 0 Mis6 Sel1 PF08238.12 EPE34360.1 - 1.3e-10 41.6 21.2 0.0003 21.4 0.1 6.9 7 0 0 7 7 7 4 Sel1 repeat TPR_1 PF00515.28 EPE34360.1 - 0.026 14.3 0.1 0.13 12.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TBPIP PF07106.13 EPE34361.1 - 6.7e-13 48.4 0.1 1.7e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain DUF2390 PF09523.10 EPE34361.1 - 0.00067 19.9 0.9 0.011 16.0 0.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2390) zf-CCCH PF00642.24 EPE34362.1 - 7.9e-11 41.6 8.6 9.8e-06 25.3 2.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EPE34362.1 - 2.8e-10 39.9 16.6 3.6e-05 23.6 3.5 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EPE34362.1 - 8.7e-10 38.2 12.2 5.9e-05 22.8 4.8 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 EPE34362.1 - 4.3e-09 37.0 6.4 0.00011 22.9 0.4 2.5 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 EPE34362.1 - 9.5e-05 22.6 2.0 0.0002 21.6 2.0 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EPE34362.1 - 0.011 16.2 16.4 0.16 12.5 2.7 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Evr1_Alr PF04777.13 EPE34363.1 - 2.9e-30 104.7 1.9 5.2e-30 103.9 1.9 1.4 1 0 0 1 1 1 1 Erv1 / Alr family HEM4 PF02602.15 EPE34364.1 - 4.1e-44 150.7 0.0 4.9e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Insulin_TMD PF17870.1 EPE34366.1 - 0.0022 18.0 0.4 0.0022 18.0 0.4 1.5 2 0 0 2 2 2 1 Insulin receptor trans-membrane segment SARAF PF06682.12 EPE34366.1 - 0.0033 17.1 0.0 0.0038 16.9 0.0 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis FeoB_associated PF12669.7 EPE34366.1 - 0.0036 17.7 1.5 0.0076 16.6 1.5 1.6 1 0 0 1 1 1 1 FeoB-associated Cys-rich membrane protein Syndecan PF01034.20 EPE34366.1 - 0.0053 16.6 0.9 0.0087 16.0 0.9 1.3 1 0 0 1 1 1 1 Syndecan domain Amnionless PF14828.6 EPE34366.1 - 0.021 13.7 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless TNFR_16_TM PF18422.1 EPE34366.1 - 0.046 13.7 2.1 0.089 12.8 2.1 1.5 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF3262 PF11660.8 EPE34366.1 - 0.046 14.1 0.3 0.074 13.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) FtsX PF02687.21 EPE34366.1 - 0.068 13.6 0.3 0.15 12.5 0.1 1.6 2 0 0 2 2 2 0 FtsX-like permease family TRP PF06011.12 EPE34366.1 - 0.13 11.0 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel EphA2_TM PF14575.6 EPE34366.1 - 0.19 12.6 0.0 0.41 11.6 0.0 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2062 PF09835.9 EPE34366.1 - 0.21 11.5 1.6 0.22 11.4 1.6 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Podoplanin PF05808.11 EPE34366.1 - 0.55 10.3 2.8 0.5 10.5 1.3 1.7 1 1 1 2 2 2 0 Podoplanin PTP_tm PF18861.1 EPE34366.1 - 0.81 9.7 4.2 1.1 9.2 4.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Claudin_2 PF13903.6 EPE34367.1 - 0.039 13.7 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2142 PF09913.9 EPE34367.1 - 0.054 12.3 0.3 0.061 12.2 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) DUF2681 PF10883.8 EPE34367.1 - 0.22 12.0 0.1 0.22 12.0 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) SET PF00856.28 EPE34368.1 - 2.6e-12 47.5 0.2 3.9e-11 43.6 0.0 2.7 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.17 EPE34368.1 - 3.6e-09 36.0 8.7 4e-05 23.4 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EPE34368.1 - 1.4e-06 27.9 2.3 0.002 17.8 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPE34368.1 - 6.3e-05 22.9 2.7 0.0034 17.5 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPE34368.1 - 0.00085 20.0 0.0 0.046 14.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EPE34368.1 - 0.074 13.3 5.2 2.9 8.2 0.5 3.9 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EPE34368.1 - 0.077 12.7 0.0 7.2 6.4 0.0 2.8 2 1 0 2 2 2 0 TPR repeat TPR_7 PF13176.6 EPE34368.1 - 0.11 12.5 0.6 8.4 6.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat CorA PF01544.18 EPE34369.1 - 1.7e-08 34.2 2.4 6.9e-08 32.1 0.1 2.6 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein P63C PF10546.9 EPE34369.1 - 0.15 12.7 0.4 0.38 11.4 0.4 1.7 1 0 0 1 1 1 0 P63C domain Aldo_ket_red PF00248.21 EPE34370.1 - 5.9e-38 130.7 0.0 1e-36 126.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family LRR_6 PF13516.6 EPE34371.1 - 2.5e-06 27.1 11.4 0.46 10.7 0.1 6.8 7 0 0 7 7 7 5 Leucine Rich repeat RAP1 PF07218.11 EPE34372.1 - 1.6 6.9 3.8 2.6 6.2 3.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SSP160 PF06933.11 EPE34372.1 - 6.9 4.7 15.2 10 4.1 15.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Amidoligase_2 PF12224.8 EPE34373.1 - 1.9e-29 103.1 1.3 1.2e-28 100.5 1.3 1.9 1 1 0 1 1 1 1 Putative amidoligase enzyme Defensin_5 PF18251.1 EPE34373.1 - 0.41 10.8 2.5 0.69 10.1 2.5 1.3 1 0 0 1 1 1 0 Fungal defensin Copsin WD40 PF00400.32 EPE34374.1 - 0.00099 19.9 1.9 2.8 9.0 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat GARS_A PF01071.19 EPE34374.1 - 0.047 13.4 0.0 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF1917 PF08939.10 EPE34375.1 - 1.4e-75 254.6 0.3 1.7e-75 254.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Succ_CoA_lig PF13607.6 EPE34375.1 - 0.08 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Phlebovirus_NSM PF07246.11 EPE34375.1 - 0.11 11.9 0.2 0.19 11.1 0.2 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M IF4E PF01652.18 EPE34375.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic initiation factor 4E Acetyltransf_1 PF00583.25 EPE34376.1 - 8.2e-05 22.8 0.0 0.00011 22.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EPE34376.1 - 0.0025 17.7 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EPE34376.1 - 0.0092 15.7 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 EPE34376.1 - 0.097 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TLD PF07534.16 EPE34377.1 - 1.5e-26 93.3 0.0 3.6e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 TLD HD PF01966.22 EPE34378.1 - 0.14 12.3 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 HD domain Ribosomal_L27A PF00828.19 EPE34379.1 - 1.6e-20 74.0 0.0 2.5e-20 73.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 EPE34380.1 - 2.7e-44 151.5 0.0 1.4e-41 142.6 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE34380.1 - 4.2e-14 52.4 0.0 4.8e-08 32.6 0.0 3.3 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.23 EPE34380.1 - 9.5e-06 25.7 0.2 0.016 15.2 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EPE34380.1 - 0.00038 19.3 0.0 0.00063 18.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EPE34380.1 - 0.0015 18.0 0.0 0.93 8.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EPE34380.1 - 0.025 14.0 0.0 0.063 12.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EPE34380.1 - 0.047 13.3 0.0 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Cnd1_N PF12922.7 EPE34381.1 - 7.1e-64 214.6 0.3 5.9e-63 211.7 0.3 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 EPE34381.1 - 9.3e-47 159.1 10.2 6.1e-44 149.9 1.0 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EPE34381.1 - 9.1e-10 38.8 2.6 0.00048 20.5 0.0 4.9 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EPE34381.1 - 6.2e-09 35.4 6.4 0.079 13.3 0.0 6.4 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 EPE34381.1 - 0.00012 22.4 8.9 0.71 10.4 0.1 5.5 6 0 0 6 6 5 1 HEAT-like repeat RTP1_C1 PF10363.9 EPE34381.1 - 0.00096 19.3 0.3 1.9 8.7 0.0 3.8 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 EPE34381.1 - 0.0061 15.8 1.3 0.0061 15.8 1.3 3.0 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain VHS PF00790.19 EPE34381.1 - 0.016 15.1 0.6 1.6 8.6 0.0 3.5 3 0 0 3 3 3 0 VHS domain DUF573 PF04504.14 EPE34381.1 - 0.19 12.4 2.0 2.5 8.8 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF573 p450 PF00067.22 EPE34381.1 - 0.26 10.0 4.5 4.1 6.0 0.9 2.3 2 0 0 2 2 2 0 Cytochrome P450 ENTH PF01417.20 EPE34381.1 - 0.27 11.3 2.3 5.4 7.1 0.0 3.8 3 0 0 3 3 3 0 ENTH domain DUF3619 PF12279.8 EPE34382.1 - 0.48 10.8 6.2 0.6 10.4 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) HET PF06985.11 EPE34384.1 - 5.8e-31 107.8 0.2 1.1e-30 106.9 0.2 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Podoplanin PF05808.11 EPE34385.1 - 0.073 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Podoplanin CSN8_PSD8_EIF3K PF10075.9 EPE34387.1 - 1.9e-17 63.6 0.0 3.3e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Coatomer_WDAD PF04053.14 EPE34388.1 - 9.2e-146 486.4 0.0 1.3e-145 485.8 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 EPE34388.1 - 2.1e-35 120.1 19.2 1.3e-07 32.2 0.3 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE34388.1 - 6.1e-08 32.9 0.4 0.023 15.0 0.0 5.8 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPE34388.1 - 0.011 14.5 6.4 2.4 6.7 0.3 3.8 2 2 1 4 4 4 0 Nucleoporin Nup120/160 Clathrin PF00637.20 EPE34388.1 - 0.015 15.1 0.3 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS IPPT PF01715.17 EPE34388.1 - 0.046 13.5 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 IPP transferase Glyco_transf_24 PF18404.1 EPE34389.1 - 3.6e-149 495.5 2.4 6.4e-149 494.7 2.4 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EPE34389.1 - 3.6e-71 240.1 0.0 4.2e-70 236.6 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 EPE34389.1 - 3e-54 184.2 0.0 4e-50 170.7 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EPE34389.1 - 2.7e-49 167.6 0.4 5.7e-49 166.6 0.4 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EPE34389.1 - 3.2e-43 146.9 1.5 3.6e-41 140.3 0.0 3.8 4 0 0 4 4 4 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EPE34389.1 - 1.6e-42 144.0 0.0 3.7e-42 142.9 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 EPE34389.1 - 0.0012 18.5 0.1 0.0025 17.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Saf_2TM PF18303.1 EPE34390.1 - 0.22 11.1 3.7 1.9 8.0 0.3 2.7 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain MFS_1 PF07690.16 EPE34391.1 - 2.9e-25 89.0 20.1 2.9e-25 89.0 20.1 2.3 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EPE34391.1 - 1.3e-05 23.9 4.8 1.9e-05 23.3 4.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 EPE34391.1 - 0.1 10.8 13.3 0.014 13.6 4.1 2.9 2 1 0 3 3 3 0 BT1 family Rhabdo_M2 PF04785.12 EPE34393.1 - 0.21 10.9 0.0 0.3 10.4 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus matrix protein M2 Sugar_tr PF00083.24 EPE34396.1 - 7.2e-72 242.7 24.9 8.1e-72 242.5 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE34396.1 - 4.4e-09 35.7 40.4 9.1e-08 31.4 33.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPE34396.1 - 9.9e-06 24.4 19.7 0.0025 16.4 2.5 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EPE34396.1 - 0.086 11.7 13.0 0.083 11.7 8.3 2.4 2 0 0 2 2 2 0 MFS_1 like family BORCS8 PF10167.9 EPE34397.1 - 0.021 14.7 0.1 0.023 14.6 0.1 1.0 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 ParD_antitoxin PF03693.14 EPE34399.1 - 0.19 12.1 0.0 0.23 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Hemerythrin PF01814.23 EPE34403.1 - 1.1e-09 39.0 0.3 1.4e-09 38.6 0.3 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Sugar_tr PF00083.24 EPE34404.1 - 4.4e-45 154.4 21.6 7.3e-45 153.7 21.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE34404.1 - 5.2e-15 55.2 26.2 5.2e-15 55.2 26.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.6 EPE34404.1 - 8.6 6.9 5.9 9.7 6.7 1.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) SesA PF17107.5 EPE34405.1 - 3e-06 27.4 0.8 7.4e-06 26.2 0.8 1.7 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 EPE34405.1 - 1.8e-05 24.2 2.4 2.8e-05 23.6 2.4 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_2 PF12796.7 EPE34405.1 - 0.003 18.1 0.0 0.0077 16.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE34405.1 - 0.0088 16.6 0.0 0.026 15.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EPE34405.1 - 0.037 14.5 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeat YicC_N PF03755.13 EPE34405.1 - 0.13 12.7 2.6 0.25 11.8 2.6 1.4 1 0 0 1 1 1 0 YicC-like family, N-terminal region Med30 PF11315.8 EPE34405.1 - 3.4 7.9 7.2 3.2 7.9 5.1 1.8 1 1 0 2 2 2 0 Mediator complex subunit 30 SYS1 PF09801.9 EPE34406.1 - 2.6e-54 183.3 9.3 2.9e-54 183.1 9.3 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network COX6B PF02297.17 EPE34407.1 - 4.9e-25 87.6 3.5 5.8e-25 87.3 3.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb HET PF06985.11 EPE34410.1 - 1.5e-20 74.0 0.0 2.9e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-Di19 PF05605.12 EPE34412.1 - 6.7 7.1 9.6 49 4.3 0.5 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Glyco_hydro_28 PF00295.17 EPE34413.1 - 2.4e-93 312.8 15.4 2.8e-93 312.5 15.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF3431 PF11913.8 EPE34414.1 - 5e-63 212.8 0.3 5.7e-63 212.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF4088 PF13317.6 EPE34415.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) MFS_2 PF13347.6 EPE34416.1 - 0.0009 17.9 0.5 0.0014 17.3 0.5 1.4 1 1 0 1 1 1 1 MFS/sugar transport protein Virul_fac_BrkB PF03631.15 EPE34416.1 - 0.0078 15.9 2.8 0.0078 15.9 2.8 1.8 1 1 0 2 2 2 1 Virulence factor BrkB DUF2721 PF11026.8 EPE34416.1 - 0.037 13.9 0.8 0.81 9.6 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) VPS53_C PF16854.5 EPE34416.1 - 0.087 12.7 0.2 0.43 10.4 0.0 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus EcsB PF05975.12 EPE34416.1 - 0.44 9.3 6.1 0.2 10.5 0.3 2.1 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB PhoR PF11808.8 EPE34416.1 - 1.4 9.4 0.1 1.4 9.4 0.1 3.0 2 1 1 3 3 3 0 Phosphate regulon sensor protein PhoR Glyco_hydro_47 PF01532.20 EPE34417.1 - 7.7e-135 450.3 0.0 9.6e-135 450.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2206 PF09971.9 EPE34417.1 - 0.02 13.7 5.1 0.046 12.5 5.1 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) LapA_dom PF06305.11 EPE34417.1 - 0.095 12.5 0.6 19 5.1 0.4 3.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PHO4 PF01384.20 EPE34417.1 - 3.7 6.5 5.2 0.52 9.3 0.2 1.9 2 0 0 2 2 2 0 Phosphate transporter family DUF5051 PF16473.5 EPE34419.1 - 6.6e-19 68.5 0.0 9.5e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like TMEMspv1-c74-12 PF11044.8 EPE34421.1 - 0.0064 16.4 0.2 0.011 15.6 0.2 1.3 1 0 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein Pex14_N PF04695.13 EPE34421.1 - 0.04 14.6 0.1 0.077 13.6 0.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec23_trunk PF04811.15 EPE34422.1 - 8.5e-68 228.5 0.0 1.2e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EPE34422.1 - 2.3e-22 78.7 0.0 9e-22 76.9 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EPE34422.1 - 4.2e-19 69.1 0.1 8.3e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EPE34422.1 - 1.4e-16 60.2 4.9 2.5e-16 59.4 4.9 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EPE34422.1 - 6.1e-08 32.4 0.0 1.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EPE34422.1 - 0.037 13.4 0.1 0.082 12.3 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pkinase PF00069.25 EPE34423.1 - 1.3e-66 224.7 0.0 1.7e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE34423.1 - 3.2e-32 111.8 0.0 4.8e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EPE34423.1 - 0.00042 19.7 0.3 0.00074 18.9 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EPE34423.1 - 0.0035 16.4 0.4 0.0069 15.4 0.4 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EPE34423.1 - 0.0086 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPE34423.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EPE34423.1 - 0.071 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RMI1_N PF08585.12 EPE34424.1 - 1.1e-46 159.4 0.0 1.2e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein Vps51 PF08700.11 EPE34425.1 - 7e-22 77.3 0.0 1.2e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 EPE34425.1 - 0.18 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Golgi transport complex subunit 5 NYD-SP28_assoc PF14775.6 EPE34425.1 - 0.41 10.8 1.6 0.82 9.8 0.1 2.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain NIF3 PF01784.18 EPE34426.1 - 2.8e-61 207.3 0.0 3.4e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.18 EPE34427.1 - 2.3e-17 63.0 0.0 5.6e-17 61.8 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein Adaptin_N PF01602.20 EPE34428.1 - 5.3e-141 470.8 4.1 7.3e-141 470.3 4.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EPE34428.1 - 2.1e-61 206.7 7.5 3.5e-61 206.0 0.3 3.4 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EPE34428.1 - 8.1e-18 64.6 1.1 1.6e-07 31.6 0.0 5.2 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 EPE34428.1 - 5.9e-12 44.8 2.5 0.023 14.9 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 EPE34428.1 - 8e-05 23.1 0.1 0.29 11.7 0.0 4.9 4 1 1 5 5 5 1 HEAT-like repeat CLASP_N PF12348.8 EPE34428.1 - 0.0013 18.3 0.1 2.2 7.8 0.0 3.3 2 1 1 3 3 3 2 CLASP N terminal UNC45-central PF11701.8 EPE34428.1 - 0.0032 17.4 0.3 2.6 8.0 0.0 3.2 2 2 0 2 2 2 2 Myosin-binding striated muscle assembly central Arm PF00514.23 EPE34428.1 - 0.038 14.1 1.5 25 5.1 0.0 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EPE34428.1 - 0.048 13.7 0.0 3.8 7.6 0.0 3.1 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain CAAP1 PF15335.6 EPE34428.1 - 0.11 13.1 1.5 0.47 11.0 0.1 2.8 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 Fungal_trans_2 PF11951.8 EPE34429.1 - 4.6e-11 42.1 0.1 1.7e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE34429.1 - 2.2e-05 24.5 9.2 5.2e-05 23.3 9.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NusB PF01029.18 EPE34429.1 - 0.061 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 NusB family zf-C2H2 PF00096.26 EPE34430.1 - 0.0032 17.9 0.9 0.0032 17.9 0.9 3.4 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE34430.1 - 0.028 15.2 0.9 0.028 15.2 0.9 3.2 4 0 0 4 4 4 0 C2H2-type zinc finger Xpo1 PF08389.12 EPE34431.1 - 1.7e-07 31.4 3.6 3.4e-05 23.9 0.1 3.8 3 0 0 3 3 3 2 Exportin 1-like protein IBN_N PF03810.19 EPE34431.1 - 0.00041 20.2 1.0 0.002 18.0 0.2 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Glyco_hydro_5_C PF18564.1 EPE34432.1 - 1.7e-23 83.0 0.0 4.7e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EPE34432.1 - 6.2e-15 55.4 2.8 9.6e-10 38.3 2.4 2.7 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 EPE34432.1 - 3.4e-05 23.4 1.0 0.075 12.4 0.1 2.2 2 0 0 2 2 2 2 Beta-galactosidase Glyco_hydro_35 PF01301.19 EPE34432.1 - 0.035 13.7 0.2 0.065 12.9 0.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 TPR_16 PF13432.6 EPE34433.1 - 1.8e-29 102.1 29.4 1.7e-08 35.0 0.9 11.5 13 0 0 13 13 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 EPE34433.1 - 1e-27 93.9 41.9 0.0023 17.9 0.0 15.9 14 1 1 15 15 15 8 Tetratricopeptide repeat TPR_19 PF14559.6 EPE34433.1 - 6.5e-27 93.8 23.8 8.5e-06 26.2 5.7 11.5 10 3 2 12 12 12 5 Tetratricopeptide repeat TPR_1 PF00515.28 EPE34433.1 - 1.5e-26 91.0 32.9 0.00049 19.8 0.1 13.1 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_17 PF13431.6 EPE34433.1 - 2.5e-23 80.7 19.3 0.11 13.0 0.0 15.8 15 1 1 16 16 16 4 Tetratricopeptide repeat TPR_14 PF13428.6 EPE34433.1 - 7.7e-22 76.1 24.5 0.042 14.7 0.2 13.6 10 5 4 14 14 13 6 Tetratricopeptide repeat TPR_8 PF13181.6 EPE34433.1 - 5.4e-19 66.8 38.5 0.085 13.1 0.7 13.6 17 0 0 17 17 15 7 Tetratricopeptide repeat TPR_11 PF13414.6 EPE34433.1 - 1.6e-17 62.9 38.5 0.00048 19.8 0.0 10.7 11 1 1 12 12 12 6 TPR repeat TPR_9 PF13371.6 EPE34433.1 - 2.3e-12 46.9 7.2 0.00078 19.5 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EPE34433.1 - 3.7e-11 43.1 38.7 0.0015 18.8 0.3 13.0 10 4 4 14 14 13 6 Tetratricopeptide repeat TPR_6 PF13174.6 EPE34433.1 - 4.2e-11 42.7 21.1 0.028 15.0 0.0 12.8 14 1 0 14 14 14 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE34433.1 - 2.6e-08 34.0 20.7 0.0074 16.5 0.9 7.8 6 2 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EPE34433.1 - 1.3e-07 31.2 24.7 0.043 13.8 0.0 11.8 12 2 1 13 13 13 2 Tetratricopeptide repeat TPR_22 PF18833.1 EPE34433.1 - 3.2e-06 27.2 0.0 1.3e-05 25.2 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat ChAPs PF09295.10 EPE34433.1 - 0.0053 15.8 4.8 10 5.0 0.0 5.2 5 1 1 6 6 6 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF5588 PF17826.1 EPE34433.1 - 0.0059 15.5 0.0 0.6 8.9 0.0 2.6 2 0 0 2 2 2 1 Family of unknown function (DUF5588) TPR_10 PF13374.6 EPE34433.1 - 0.019 14.8 12.1 3.4 7.7 0.1 7.5 8 0 0 8 8 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EPE34433.1 - 0.026 14.6 10.2 3.7 7.7 0.4 6.9 8 1 1 9 9 8 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 EPE34433.1 - 0.051 13.6 4.1 3.9 7.6 0.1 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.9 EPE34433.1 - 0.063 13.0 0.5 1.5 8.5 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) DIT1_PvcA PF05141.12 EPE34433.1 - 0.18 11.2 0.4 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein FAT PF02259.23 EPE34433.1 - 1 8.5 8.1 4.7 6.3 0.1 4.4 5 0 0 5 5 5 0 FAT domain Sec61_beta PF03911.16 EPE34434.1 - 2.5 8.2 0.0 2.5 8.2 0.0 2.8 3 0 0 3 3 3 0 Sec61beta family Ribosomal_S17 PF00366.20 EPE34436.1 - 3.1e-18 65.6 3.5 3.8e-18 65.4 2.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S17 PhyH PF05721.13 EPE34436.1 - 0.074 13.3 0.0 0.2 11.9 0.0 1.8 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) DUF4051 PF13260.6 EPE34436.1 - 0.12 12.2 0.6 0.27 11.0 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) LolB PF03550.14 EPE34436.1 - 0.12 12.4 4.4 0.24 11.4 1.1 2.3 2 0 0 2 2 2 0 Outer membrane lipoprotein LolB DUF3632 PF12311.8 EPE34437.1 - 4.8e-32 111.8 2.1 6.1e-32 111.5 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Pec_lyase_C PF00544.19 EPE34438.1 - 2.2e-11 43.8 6.2 1.7e-09 37.6 6.2 2.4 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EPE34438.1 - 0.00011 22.1 8.8 0.012 15.4 8.3 2.6 1 1 1 2 2 2 1 Right handed beta helix region CompInhib_SCIN PF11546.8 EPE34439.1 - 0.00036 20.5 0.3 1.4 8.9 0.1 2.9 1 1 1 3 3 3 2 Staphylococcal complement inhibitor SCIN Death PF00531.22 EPE34439.1 - 0.0041 17.2 0.3 8.8 6.6 0.0 3.3 3 0 0 3 3 3 2 Death domain Ribosomal_L30 PF00327.20 EPE34439.1 - 0.022 14.7 0.1 16 5.5 0.0 3.3 3 0 0 3 3 3 0 Ribosomal protein L30p/L7e CAAP1 PF15335.6 EPE34439.1 - 0.082 13.5 0.0 36 5.0 0.0 3.1 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 Pep1_7 PF17232.2 EPE34439.1 - 0.17 12.3 0.4 6.3 7.3 0.0 2.9 2 2 1 3 3 3 0 Elicitor peptide 1-7 PAP2 PF01569.21 EPE34440.1 - 4.7e-26 91.2 3.6 4.7e-26 91.2 3.6 1.7 2 0 0 2 2 2 1 PAP2 superfamily BPD_transp_2 PF02653.16 EPE34440.1 - 1.2 8.2 9.6 0.21 10.8 3.0 2.1 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component HK97-gp10_like PF04883.12 EPE34441.1 - 0.18 12.8 0.0 0.45 11.5 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component LRR_4 PF12799.7 EPE34441.1 - 0.26 11.8 1.8 46 4.6 0.2 4.1 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) HET PF06985.11 EPE34442.1 - 2.7e-24 86.2 0.1 5.7e-24 85.1 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Asp PF00026.23 EPE34443.1 - 3e-40 138.6 0.1 4.3e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 EPE34443.1 - 3.7e-07 30.7 0.6 0.00078 20.0 0.5 3.7 2 2 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EPE34443.1 - 0.0019 18.7 0.1 0.2 12.3 0.0 3.5 2 2 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EPE34443.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Fungal_trans_2 PF11951.8 EPE34444.1 - 4.7e-11 42.1 1.5 8.7e-09 34.7 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE34444.1 - 2.1e-07 30.9 13.6 8.5e-07 29.0 9.4 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_20 PF00982.21 EPE34445.1 - 1.2e-195 650.8 0.0 1.4e-195 650.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 EPE34445.1 - 0.08 12.6 0.2 0.31 10.7 0.1 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain Peptidase_U32_C PF16325.5 EPE34446.1 - 0.069 13.4 0.9 10 6.5 0.0 2.7 3 0 0 3 3 3 0 Peptidase family U32 C-terminal domain MDH PF02315.16 EPE34446.1 - 0.11 12.6 0.3 0.71 10.0 0.1 2.0 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit DUF5425 PF17472.2 EPE34447.1 - 0.078 13.8 0.1 0.17 12.7 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5425) Nore1-SARAH PF16517.5 EPE34447.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain SHR3_chaperone PF08229.11 EPE34449.1 - 0.98 8.4 7.7 1.2 8.1 0.1 2.8 1 1 2 3 3 3 0 ER membrane protein SH3 MFS_1 PF07690.16 EPE34450.1 - 5.8e-16 58.4 60.7 3.5e-15 55.8 28.2 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily DJ-1_PfpI PF01965.24 EPE34451.1 - 4.2e-13 49.4 0.0 4.8e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Yeast-kill-tox PF09207.11 EPE34451.1 - 0.064 13.9 0.1 0.12 13.1 0.1 1.4 1 0 0 1 1 1 0 Yeast killer toxin AATase PF07247.12 EPE34452.1 - 2.1e-06 26.6 0.2 1.1e-05 24.2 0.2 2.0 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 EPE34452.1 - 2.2e-05 23.3 0.2 3.5e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 Condensation domain Abhydrolase_3 PF07859.13 EPE34453.1 - 5.7e-43 147.2 0.0 7.6e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EPE34453.1 - 3.7e-12 45.9 0.0 2.2e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 EPE34453.1 - 0.0011 19.6 0.2 0.0036 17.9 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EPE34453.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EPE34453.1 - 0.015 14.5 0.0 0.071 12.4 0.0 1.9 1 1 1 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 EPE34453.1 - 0.035 13.6 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EPE34453.1 - 0.096 12.1 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DIT1_PvcA PF05141.12 EPE34454.1 - 2.3e-91 306.1 0.0 3.4e-91 305.5 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein ABC_tran PF00005.27 EPE34454.1 - 2e-09 38.1 0.7 3.8e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EPE34454.1 - 0.0041 17.1 0.1 0.013 15.4 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AMP-binding PF00501.28 EPE34455.1 - 4.5e-25 88.1 0.0 8.2e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.15 EPE34455.1 - 4.6e-10 38.7 0.0 1.3e-08 34.0 0.0 2.3 1 1 0 1 1 1 1 Transferase family PP-binding PF00550.25 EPE34455.1 - 4.6e-09 36.5 0.2 1.4e-08 34.9 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site MFS_1 PF07690.16 EPE34456.1 - 9.8e-39 133.3 50.7 1.8e-38 132.4 48.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE34456.1 - 5e-11 41.7 8.2 5e-11 41.7 8.2 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AAA PF00004.29 EPE34457.1 - 3.6e-38 131.0 0.0 6.6e-38 130.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPE34457.1 - 5.8e-08 32.4 0.0 1.4e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 EPE34457.1 - 1.1e-07 31.7 0.0 2.6e-06 27.3 0.0 3.1 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 EPE34457.1 - 1.9e-05 24.9 0.1 0.00045 20.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EPE34457.1 - 6.6e-05 22.7 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EPE34457.1 - 0.00057 19.2 0.1 0.0017 17.6 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 EPE34457.1 - 0.002 18.1 0.1 0.0074 16.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPE34457.1 - 0.0024 18.3 0.2 0.0024 18.3 0.2 2.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EPE34457.1 - 0.0039 17.3 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EPE34457.1 - 0.0046 16.7 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EPE34457.1 - 0.0052 16.2 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EPE34457.1 - 0.0095 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EPE34457.1 - 0.023 14.7 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EPE34457.1 - 0.045 14.3 0.0 0.17 12.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EPE34457.1 - 0.062 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EPE34457.1 - 0.07 12.7 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EPE34457.1 - 0.072 13.2 4.7 0.089 13.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EPE34457.1 - 0.14 11.7 0.0 0.39 10.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EPE34457.1 - 0.18 11.5 0.0 0.68 9.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 EPE34457.1 - 0.19 11.5 10.0 0.98 9.1 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EPE34457.1 - 0.25 11.6 1.2 0.85 9.8 0.1 2.5 3 0 0 3 3 3 0 AAA domain Mito_carr PF00153.27 EPE34458.1 - 2.2e-68 226.2 4.4 7.4e-23 80.3 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EPE34458.1 - 0.00049 19.4 4.2 0.18 11.0 0.2 3.3 1 1 1 3 3 3 3 Gammaproteobacterial serine protease APG9 PF04109.16 EPE34459.1 - 3.1e-185 616.8 10.7 3.7e-185 616.5 10.7 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 COG6 PF06419.11 EPE34460.1 - 6.6e-226 751.4 5.5 7.4e-226 751.2 5.5 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 GAS PF13851.6 EPE34460.1 - 0.035 13.4 2.6 0.082 12.2 2.1 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding COG2 PF06148.11 EPE34460.1 - 0.036 14.2 3.0 0.079 13.0 0.9 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 GARP PF16731.5 EPE34460.1 - 0.064 12.9 1.4 0.15 11.7 0.3 2.1 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Bombinin PF05298.11 EPE34460.1 - 0.14 11.8 0.3 18 5.0 0.0 2.8 3 0 0 3 3 3 0 Bombinin ApbA_C PF08546.11 EPE34461.1 - 1.8e-37 128.3 0.0 8.4e-37 126.2 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EPE34461.1 - 1.5e-21 76.7 0.1 2.6e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 EPE34462.1 - 1.2e-26 93.7 0.0 2.1e-26 92.9 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE34462.1 - 1.6e-06 28.1 0.0 2.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE34462.1 - 0.00015 21.3 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE34462.1 - 0.024 13.6 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 EPE34462.1 - 0.15 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain His_Phos_1 PF00300.22 EPE34463.1 - 5e-19 68.8 0.0 8.1e-18 64.8 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Chromate_transp PF02417.15 EPE34464.1 - 1.1e-57 194.6 31.2 2.4e-32 112.2 11.9 2.6 3 0 0 3 3 3 2 Chromate transporter p450 PF00067.22 EPE34465.1 - 1.6e-07 30.4 0.0 1.9e-07 30.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 3Beta_HSD PF01073.19 EPE34467.1 - 9.4e-54 182.3 0.0 1.2e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPE34467.1 - 1.3e-25 90.3 0.0 1.7e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE34467.1 - 1.4e-14 54.3 0.0 3.2e-13 49.8 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPE34467.1 - 3.8e-13 49.2 0.0 1e-11 44.5 0.0 2.1 1 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 EPE34467.1 - 8.6e-11 41.5 0.0 4.2e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EPE34467.1 - 2e-08 34.4 0.0 2.7e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EPE34467.1 - 5.4e-06 25.7 0.0 2.1e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EPE34467.1 - 2.4e-05 24.4 0.6 0.0018 18.3 0.6 3.0 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 EPE34467.1 - 0.096 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family TrkA_N PF02254.18 EPE34467.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Rft-1 PF04506.13 EPE34468.1 - 5.5e-80 269.6 6.3 1.4e-79 268.2 6.3 1.6 1 1 0 1 1 1 1 Rft protein DUF485 PF04341.12 EPE34468.1 - 0.17 11.9 5.3 1.9 8.5 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Polysacc_synt PF01943.17 EPE34468.1 - 0.35 10.2 17.7 3.6 6.9 17.7 2.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DEAD PF00270.29 EPE34469.1 - 1e-48 165.4 0.0 3.7e-48 163.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE34469.1 - 1.9e-33 115.1 0.0 3e-29 101.6 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EPE34469.1 - 0.0039 16.4 0.0 0.0039 16.4 0.0 2.1 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 EPE34469.1 - 0.021 14.1 0.0 0.021 14.1 0.0 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 EPE34469.1 - 0.047 12.5 0.0 0.24 10.1 0.0 2.1 2 1 1 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 EPE34469.1 - 0.11 12.8 1.2 0.99 9.7 0.6 2.5 2 1 0 2 2 2 0 AAA domain NifU_N PF01592.16 EPE34470.1 - 4e-53 179.0 0.0 5.1e-53 178.6 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 EPE34470.1 - 0.081 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain UCH PF00443.29 EPE34471.1 - 3.8e-34 118.3 0.0 5.6e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EPE34471.1 - 1.4e-23 83.0 6.7 4.3e-18 65.4 1.4 3.1 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 EPE34471.1 - 1.1e-22 79.5 0.0 3.5e-10 39.6 0.1 2.8 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 EPE34471.1 - 1.8e-21 75.7 1.4 5e-21 74.2 0.1 2.3 2 0 0 2 2 2 1 Variant UBP zinc finger UCH_1 PF13423.6 EPE34471.1 - 1.8e-17 63.9 0.8 4e-14 52.9 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 EPE34471.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Fungal_trans PF04082.18 EPE34472.1 - 1.6e-14 53.6 1.2 4.5e-14 52.1 1.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPE34472.1 - 2.6e-05 24.4 13.2 0.013 15.9 3.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE34472.1 - 0.13 13.2 10.5 3.8 8.6 1.4 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_M20 PF01546.28 EPE34473.1 - 1.4e-27 96.7 0.0 2.6e-27 95.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EPE34473.1 - 2.6e-14 53.0 0.0 4.5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EPE34473.1 - 0.029 14.1 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 AMPK1_CBM PF16561.5 EPE34474.1 - 2e-21 76.0 1.0 4.2e-21 75.0 1.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 EPE34474.1 - 0.18 12.1 0.2 0.4 11.1 0.2 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SIR4_SID PF16991.5 EPE34474.1 - 1.7 8.7 5.6 13 5.8 0.1 2.7 1 1 1 2 2 2 0 Sir4 SID domain cNMP_binding PF00027.29 EPE34475.1 - 4.6e-39 132.4 0.0 1.5e-20 73.1 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain BCAS2 PF05700.11 EPE34476.1 - 5.5e-64 215.7 0.5 6.1e-64 215.5 0.5 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Ceramidase_alk PF04734.13 EPE34477.1 - 1.6e-221 736.3 0.0 1.9e-221 736.1 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EPE34477.1 - 6.9e-59 198.5 0.0 1.1e-58 197.8 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal RNA_pol_Rpb1_5 PF04998.17 EPE34478.1 - 2.2e-77 260.1 0.1 4.8e-77 259.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EPE34478.1 - 2.4e-74 249.1 0.3 7e-74 247.6 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 EPE34478.1 - 4.9e-57 193.6 0.2 6.2e-52 176.9 0.1 2.4 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 EPE34478.1 - 6.3e-39 133.4 0.0 1.7e-38 132.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EPE34478.1 - 1.9e-26 92.1 1.5 5.4e-26 90.6 0.1 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 NIF PF03031.18 EPE34479.1 - 1.9e-55 186.9 0.0 2.9e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IF-2B PF01008.17 EPE34480.1 - 3.4e-58 197.1 7.7 2.4e-31 109.0 0.0 2.8 2 1 0 2 2 2 2 Initiation factor 2 subunit family DUF4646 PF15496.6 EPE34481.1 - 0.065 13.9 0.1 0.14 12.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) SR-25 PF10500.9 EPE34482.1 - 0.009 15.6 7.6 0.009 15.6 7.6 3.0 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 EPE34482.1 - 0.085 10.9 17.5 0.13 10.3 17.5 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Dehydrin PF00257.19 EPE34482.1 - 1.1 9.8 9.3 0.043 14.4 2.2 2.2 2 0 0 2 2 2 0 Dehydrin adh_short_C2 PF13561.6 EPE34483.1 - 7.9e-41 140.1 0.0 1.4e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE34483.1 - 4.3e-40 137.3 0.0 6.3e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE34483.1 - 5.4e-11 42.7 1.4 1e-09 38.6 1.4 2.2 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EPE34483.1 - 0.00052 19.5 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EPE34483.1 - 0.0055 16.2 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HI0933_like PF03486.14 EPE34483.1 - 0.035 12.8 1.0 1.2 7.8 0.4 2.3 1 1 1 2 2 2 0 HI0933-like protein ADH_zinc_N PF00107.26 EPE34483.1 - 0.037 14.0 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox PF00070.27 EPE34483.1 - 0.094 13.3 0.4 0.29 11.7 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1712 PF08217.11 EPE34484.1 - 6.4e-16 58.0 0.0 2.3e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.19 EPE34485.1 - 6.7e-27 94.4 0.0 9.7e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EPE34485.1 - 0.0026 18.0 0.7 0.027 14.7 0.7 2.3 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain CIAPIN1 PF05093.13 EPE34486.1 - 2.2e-41 140.4 3.1 3.5e-41 139.8 3.1 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EPE34486.1 - 6.6e-40 136.4 0.0 9.5e-40 135.9 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus SPAR_C PF11881.8 EPE34486.1 - 0.15 12.0 1.0 0.25 11.2 1.0 1.3 1 0 0 1 1 1 0 C-terminal domain of SPAR protein adh_short_C2 PF13561.6 EPE34488.1 - 1.9e-40 138.9 0.1 2.4e-40 138.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE34488.1 - 1.1e-35 122.9 0.2 1.4e-35 122.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE34488.1 - 2.5e-09 37.3 0.1 3.5e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 KR domain ICE2 PF08426.10 EPE34490.1 - 6.1e-129 430.7 1.6 6.8e-129 430.5 1.6 1.0 1 0 0 1 1 1 1 ICE2 DUF3074 PF11274.8 EPE34490.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) UPF0160 PF03690.13 EPE34491.1 - 1.2e-136 455.5 0.0 1.4e-136 455.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Endosulfine PF04667.17 EPE34492.1 - 5.2e-28 97.0 0.1 9.9e-28 96.1 0.1 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.13 EPE34493.1 - 1.9e-83 279.0 0.0 2.1e-83 278.8 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.22 EPE34494.1 - 7.3e-112 374.8 0.0 9.4e-112 374.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase WD40 PF00400.32 EPE34495.1 - 7.3e-16 58.3 4.9 0.0013 19.5 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE34495.1 - 7e-08 32.7 0.0 0.092 13.1 0.0 4.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EPE34495.1 - 0.025 13.9 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain PilX PF13681.6 EPE34495.1 - 0.027 14.8 0.0 0.11 12.9 0.0 2.2 1 1 0 1 1 1 0 Type IV pilus assembly protein PilX C-term Ge1_WD40 PF16529.5 EPE34495.1 - 0.048 12.6 0.2 0.12 11.3 0.0 1.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CTP_transf_like PF01467.26 EPE34497.1 - 1.7e-25 89.9 0.0 3.5e-21 75.9 0.0 3.5 2 1 0 2 2 2 2 Cytidylyltransferase-like Aminotran_4 PF01063.19 EPE34498.1 - 1.8e-23 83.5 0.0 2.7e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Phg_2220_C PF09524.10 EPE34499.1 - 0.25 11.4 1.8 2.1 8.5 0.1 2.8 2 1 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) HSCB_C PF07743.13 EPE34499.1 - 0.97 10.0 9.2 2.5 8.7 3.4 3.2 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain Qua1 PF16274.5 EPE34499.1 - 1.1 9.1 6.7 0.74 9.7 3.3 2.5 3 0 0 3 3 3 0 Qua1 domain Flavoprotein PF02441.19 EPE34500.1 - 2.6e-45 154.0 0.0 4.2e-45 153.3 0.0 1.3 1 1 0 1 1 1 1 Flavoprotein Glutaredoxin PF00462.24 EPE34501.1 - 1.6e-15 57.0 0.0 2.6e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DPBB_1 PF03330.18 EPE34503.1 - 2.5e-06 27.6 0.2 7.8e-06 26.1 0.0 2.0 2 1 0 2 2 2 1 Lytic transglycolase zf-TFIIB PF13453.6 EPE34503.1 - 0.037 13.3 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger Aldedh PF00171.22 EPE34504.1 - 3.5e-78 263.2 0.0 4.2e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MRP-S28 PF10213.9 EPE34505.1 - 7.6e-45 152.4 0.1 1.5e-44 151.5 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Glyco_tran_28_C PF04101.16 EPE34506.1 - 1.7e-16 60.6 0.0 4.9e-16 59.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain AIM5 PF17050.5 EPE34508.1 - 1.4e-22 80.2 6.5 4.6e-22 78.6 6.5 1.9 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Ribosomal_L17 PF01196.19 EPE34509.1 - 8e-34 116.4 0.0 1.3e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Mrpl_C PF18502.1 EPE34509.1 - 0.02 15.1 0.0 0.096 13.0 0.0 1.9 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain UTP25 PF06862.12 EPE34510.1 - 1e-200 667.5 0.1 1.2e-200 667.3 0.1 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 MitMem_reg PF13012.6 EPE34511.1 - 2.8e-18 66.3 0.5 5.3e-18 65.5 0.1 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EPE34511.1 - 3.4e-16 59.3 0.0 5.2e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SUZ PF12752.7 EPE34512.1 - 1.5e-15 57.6 4.2 1.5e-15 57.6 4.2 3.2 3 0 0 3 3 3 1 SUZ domain R3H PF01424.22 EPE34512.1 - 2.4e-08 33.8 0.1 5.8e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 R3H domain cwf18 PF08315.12 EPE34514.1 - 4.7e-45 153.6 6.4 4.7e-45 153.6 6.4 1.6 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor HK97-gp10_like PF04883.12 EPE34514.1 - 0.23 12.5 5.1 0.62 11.1 1.4 2.4 1 1 1 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component PPR_2 PF13041.6 EPE34515.1 - 2.5e-19 69.2 0.0 2e-10 40.7 0.0 4.1 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.6 EPE34515.1 - 3.8e-13 49.3 0.0 6.9e-06 26.0 0.0 4.7 3 1 2 5 5 5 4 Pentatricopeptide repeat domain PPR PF01535.20 EPE34515.1 - 4.9e-09 35.8 0.0 0.025 14.8 0.0 4.6 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.7 EPE34515.1 - 0.00029 20.5 0.2 0.035 13.8 0.0 3.7 4 0 0 4 4 4 1 PPR repeat PPR_long PF17177.4 EPE34515.1 - 0.014 14.7 0.0 1.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP IBR PF01485.21 EPE34516.1 - 2.3e-12 46.9 43.2 2.3e-07 30.9 2.1 4.6 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain His_Phos_1 PF00300.22 EPE34517.1 - 7.3e-25 87.8 0.0 9.5e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) He_PIG PF05345.12 EPE34518.1 - 7.2e-10 38.9 24.0 0.011 15.9 1.6 5.5 5 1 0 5 5 5 4 Putative Ig domain DUF4448 PF14610.6 EPE34518.1 - 0.00051 19.9 0.0 0.0017 18.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) BatD PF13584.6 EPE34518.1 - 0.0012 17.8 0.1 0.0023 16.8 0.1 1.4 1 0 0 1 1 1 1 Oxygen tolerance TMEM154 PF15102.6 EPE34518.1 - 0.0012 18.7 0.1 0.0012 18.7 0.1 2.0 2 0 0 2 2 2 1 TMEM154 protein family DUF2207 PF09972.9 EPE34518.1 - 0.0027 16.6 0.0 0.004 16.0 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF1180 PF06679.12 EPE34518.1 - 3.9 7.9 6.4 0.51 10.7 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) PP2C PF00481.21 EPE34519.1 - 8.5e-84 281.2 0.1 1.6e-83 280.3 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C CTP_transf_like PF01467.26 EPE34520.1 - 1.7e-30 106.1 0.0 3.2e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 EPE34520.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase Oxidored_q6 PF01058.22 EPE34521.1 - 3.4e-22 78.7 0.0 5e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Mpp10 PF04006.12 EPE34522.1 - 7.3e-113 378.1 52.8 1.8e-112 376.9 52.8 1.5 1 1 0 1 1 1 1 Mpp10 protein Fe-ADH PF00465.19 EPE34523.1 - 2.1e-65 220.9 0.0 2.8e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EPE34523.1 - 6.4e-08 32.6 0.6 7.7e-06 25.8 0.2 2.4 2 1 0 2 2 2 2 Iron-containing alcohol dehydrogenase F-box PF00646.33 EPE34525.1 - 2.1e-07 30.6 0.0 0.0033 17.3 0.0 2.6 2 1 0 2 2 2 2 F-box domain F-box-like PF12937.7 EPE34525.1 - 3.9e-07 29.8 0.0 0.0057 16.5 0.1 2.3 2 0 0 2 2 2 2 F-box-like Tctex-1 PF03645.13 EPE34526.1 - 4.1e-39 133.0 0.0 4.8e-39 132.8 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.15 EPE34527.1 - 3.1e-15 56.4 4.9 2.5e-14 53.5 4.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Bax1-I PF01027.20 EPE34527.1 - 0.027 14.3 6.1 0.035 13.9 6.1 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Alba PF01918.21 EPE34528.1 - 7.9e-07 28.8 0.1 1.7e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 Alba LptF_LptG PF03739.14 EPE34529.1 - 0.011 14.6 0.9 0.017 14.0 0.9 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG RRM_1 PF00076.22 EPE34531.1 - 5.1e-16 58.2 0.0 8.2e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spc7 PF08317.11 EPE34531.1 - 0.0041 16.1 3.1 0.0047 15.9 3.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4201 PF13870.6 EPE34531.1 - 0.0068 16.2 0.6 0.0087 15.8 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) UPF0242 PF06785.11 EPE34531.1 - 0.024 14.7 2.0 0.031 14.4 2.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Med9 PF07544.13 EPE34531.1 - 0.03 14.4 0.9 0.046 13.8 0.9 1.2 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 BLOC1_2 PF10046.9 EPE34531.1 - 0.042 14.2 1.3 0.057 13.7 1.3 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5082 PF16888.5 EPE34531.1 - 0.064 13.5 4.6 0.083 13.2 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) FDF PF09532.10 EPE34531.1 - 0.08 13.8 2.0 0.11 13.3 2.0 1.1 1 0 0 1 1 1 0 FDF domain RRM_occluded PF16842.5 EPE34531.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 2 1 0 2 2 2 0 Occluded RNA-recognition motif DUF724 PF05266.14 EPE34531.1 - 0.11 12.3 4.8 0.15 11.9 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TPD52 PF04201.15 EPE34531.1 - 0.25 10.9 2.4 0.33 10.6 2.4 1.1 1 0 0 1 1 1 0 Tumour protein D52 family DivIC PF04977.15 EPE34531.1 - 0.86 9.4 4.3 1.3 8.8 4.3 1.3 1 0 0 1 1 1 0 Septum formation initiator GRP PF07172.11 EPE34531.1 - 4.7 8.0 18.1 0.52 11.0 13.2 1.8 2 0 0 2 2 2 0 Glycine rich protein family HECT PF00632.25 EPE34532.1 - 4.1e-93 312.2 0.0 5.8e-93 311.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EPE34532.1 - 2.7e-32 110.5 21.1 5.9e-11 42.3 3.1 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 EPE34532.1 - 1.1e-18 67.4 0.0 2.8e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain Atrophin-1 PF03154.15 EPE34533.1 - 0.19 10.0 1.8 0.21 9.8 1.8 1.0 1 0 0 1 1 1 0 Atrophin-1 family SPX PF03105.19 EPE34534.1 - 2e-07 31.3 13.6 0.0038 17.2 0.0 3.4 2 1 2 4 4 4 3 SPX domain CorA PF01544.18 EPE34534.1 - 2.3 7.4 6.1 0.1 11.9 0.3 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Syndecan PF01034.20 EPE34534.1 - 5.5 7.0 5.5 0.56 10.2 0.3 2.0 2 0 0 2 2 2 0 Syndecan domain adh_short_C2 PF13561.6 EPE34535.1 - 6.5e-54 183.0 0.0 7.8e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE34535.1 - 7.8e-41 139.7 0.0 9.8e-41 139.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE34535.1 - 2.9e-11 43.6 0.0 4.1e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 KR domain PALP PF00291.25 EPE34535.1 - 0.14 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Hydin_ADK PF17213.3 EPE34536.1 - 0.14 12.4 2.8 0.18 12.1 2.8 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Mucin PF01456.17 EPE34536.1 - 4.6 7.2 13.4 6.4 6.8 13.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein ALAD PF00490.21 EPE34538.1 - 2.4e-118 394.9 0.0 3.2e-118 394.5 0.0 1.2 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Acyl_transf_1 PF00698.21 EPE34539.1 - 8.5e-19 68.2 0.0 4.9e-14 52.6 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain ROS_MUCR PF05443.11 EPE34539.1 - 0.046 13.8 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Sedlin_N PF04628.13 EPE34540.1 - 5.1e-06 26.6 0.0 6.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EPE34540.1 - 0.16 11.9 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Sybindin-like family AFG1_ATPase PF03969.16 EPE34541.1 - 1.4e-61 208.4 0.2 2.9e-27 95.5 0.0 5.1 4 1 0 5 5 5 5 AFG1-like ATPase AAA_5 PF07728.14 EPE34541.1 - 2e-05 24.6 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPE34541.1 - 2.1e-05 25.0 1.8 0.054 13.9 0.0 3.4 3 1 1 4 4 4 2 AAA ATPase domain AAA PF00004.29 EPE34541.1 - 0.00012 22.5 0.0 0.00054 20.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPE34541.1 - 0.0035 17.6 0.0 0.014 15.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EPE34541.1 - 0.06 13.1 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 EPE34541.1 - 0.16 11.6 0.0 0.55 9.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 EPE34541.1 - 0.18 11.1 0.0 0.44 9.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EPE34541.1 - 0.19 12.2 0.1 31 5.1 0.0 2.6 1 1 1 2 2 2 0 ABC transporter AAA_7 PF12775.7 EPE34541.1 - 0.21 11.1 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Nucleoporin_C PF03177.14 EPE34542.1 - 1.3e-166 555.9 24.5 1.6e-166 555.6 24.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EPE34542.1 - 1.8e-67 228.0 0.0 2.3e-67 227.6 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like DUF2949 PF11165.8 EPE34542.1 - 0.025 14.9 0.1 0.12 12.7 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2949) Pkinase PF00069.25 EPE34544.1 - 8.4e-28 97.5 0.0 1.1e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE34544.1 - 1.9e-14 53.6 0.0 2.6e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPE34544.1 - 7.6e-07 28.2 0.0 1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase EMP24_GP25L PF01105.24 EPE34545.1 - 1.8e-52 177.9 0.0 2.1e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SANT_DAMP1_like PF16282.5 EPE34546.1 - 1.5e-32 111.6 0.1 2.9e-32 110.7 0.1 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Hexapep PF00132.24 EPE34547.1 - 1.4e-10 40.5 17.9 5.2e-06 26.0 2.1 3.6 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 EPE34547.1 - 2.3e-10 40.5 0.1 5.7e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 EPE34547.1 - 2.8e-09 36.6 17.4 1.9e-05 24.3 4.5 3.3 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.18 EPE34547.1 - 4.6e-09 36.3 8.1 9.7e-09 35.2 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-oxoacid_dh PF00198.23 EPE34548.1 - 2.6e-79 266.0 0.1 3.5e-79 265.5 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EPE34548.1 - 1.1e-17 63.6 0.8 2.4e-17 62.5 0.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 EPE34548.1 - 0.0039 17.9 0.2 0.13 12.9 0.2 2.4 1 1 0 1 1 1 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EPE34548.1 - 0.019 14.8 0.1 0.99 9.3 0.0 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like Apt1 PF10351.9 EPE34548.1 - 1.6 7.5 8.3 2.2 7.0 8.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 EPE34548.1 - 1.8 7.2 7.1 2.6 6.7 7.1 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EPE34548.1 - 2.7 6.6 7.8 3.6 6.2 7.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 EPE34548.1 - 5.1 5.8 6.8 6.5 5.4 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FAM76 PF16046.5 EPE34548.1 - 8.4 5.6 8.2 81 2.4 0.0 2.1 2 0 0 2 2 2 0 FAM76 protein Complex1_LYR PF05347.15 EPE34549.1 - 4.1e-09 36.4 0.6 5.4e-09 36.0 0.6 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EPE34549.1 - 0.39 11.5 1.9 0.89 10.3 1.9 1.6 1 1 0 1 1 1 0 Complex1_LYR-like Histone_H2A_C PF16211.5 EPE34550.1 - 2.9e-21 74.9 2.7 5.1e-21 74.1 2.7 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EPE34550.1 - 7.6e-17 61.9 0.0 9.9e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EPE34550.1 - 9.9e-06 25.8 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EPE34551.1 - 1.6e-21 77.0 2.3 2e-21 76.7 2.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EPE34551.1 - 4.9e-05 23.5 0.4 0.0001 22.5 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EPE34551.1 - 0.00025 21.5 0.0 0.00042 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 EPE34551.1 - 0.033 13.8 0.1 0.08 12.6 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain R3H PF01424.22 EPE34552.1 - 1.1e-11 44.5 0.0 3.9e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 R3H domain G-patch PF01585.23 EPE34552.1 - 8.7e-10 38.3 0.2 2.7e-09 36.8 0.2 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EPE34552.1 - 0.00021 21.3 0.2 0.00021 21.3 0.2 2.8 3 0 0 3 3 3 1 G-patch domain Chromo PF00385.24 EPE34552.1 - 0.0033 17.3 0.0 0.0089 15.9 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_C54 PF03416.19 EPE34553.1 - 2.2e-94 315.9 0.0 2.7e-94 315.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_M14 PF00246.24 EPE34553.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Zinc carboxypeptidase DnaJ PF00226.31 EPE34554.1 - 1.2e-24 86.1 0.4 1.2e-24 86.1 0.4 2.9 3 0 0 3 3 3 1 DnaJ domain zf-C2H2_jaz PF12171.8 EPE34554.1 - 4.4e-10 39.6 6.2 1.1e-09 38.3 6.2 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPE34554.1 - 3.6e-09 36.7 2.9 3.6e-09 36.7 2.9 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EPE34554.1 - 5.4e-07 29.9 3.2 0.022 15.6 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EPE34554.1 - 1.1e-05 25.7 10.6 0.001 19.4 4.6 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EPE34554.1 - 2e-05 24.8 5.8 0.044 14.2 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type RPT PF13446.6 EPE34554.1 - 0.031 14.2 0.0 0.1 12.5 0.0 1.9 1 1 0 1 1 1 0 A repeated domain in UCH-protein E6 PF00518.17 EPE34554.1 - 0.12 12.8 1.5 10 6.6 0.1 2.4 2 0 0 2 2 2 0 Early Protein (E6) zf-H2C2_2 PF13465.6 EPE34554.1 - 0.38 11.3 3.1 5.1 7.7 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Elf1 PF05129.13 EPE34554.1 - 0.54 10.3 7.0 11 6.1 2.8 2.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_6 PF13912.6 EPE34554.1 - 2.1 8.5 5.6 0.93 9.6 1.5 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger SPX PF03105.19 EPE34555.1 - 9.9e-57 193.6 0.8 1.5e-56 193.0 0.8 1.3 1 0 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 EPE34555.1 - 4.3e-08 32.9 8.3 7.2e-08 32.2 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE34555.1 - 5.2e-07 29.4 9.7 9.3e-07 28.6 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPE34555.1 - 1.2e-05 25.4 7.9 2.2e-05 24.5 7.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EPE34555.1 - 2.2e-05 24.3 7.5 4.5e-05 23.3 7.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EPE34555.1 - 0.00013 21.7 9.6 0.00024 20.9 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE34555.1 - 0.00023 21.4 10.7 0.00039 20.7 10.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EPE34555.1 - 0.00028 20.9 6.4 0.00056 19.9 6.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EPE34555.1 - 0.0065 16.3 8.8 0.07 13.0 9.3 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EPE34555.1 - 0.17 11.7 8.1 0.048 13.5 3.6 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.20 EPE34555.1 - 0.73 9.6 8.5 1.6 8.5 8.5 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger YccV-like PF08755.11 EPE34556.1 - 1.7e-30 105.4 0.3 5.3e-30 103.8 0.2 1.9 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 EPE34556.1 - 3.5e-10 39.7 0.0 5.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 EPE34556.1 - 1.1e-07 31.7 0.5 2.5e-07 30.5 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE34556.1 - 3.6e-07 29.9 0.7 7.8e-07 28.8 0.7 1.6 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 EPE34556.1 - 0.00015 22.2 0.1 0.00038 20.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF4261 PF14080.6 EPE34556.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) F-box_4 PF15966.5 EPE34556.1 - 0.15 12.0 0.0 0.72 9.7 0.0 2.1 2 0 0 2 2 2 0 F-box Peptidase_C12 PF01088.21 EPE34557.1 - 4.1e-63 212.9 0.0 7.9e-63 212.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Lac_bphage_repr PF06543.12 EPE34557.1 - 0.08 12.9 0.7 21 5.2 0.0 3.1 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor PPP5 PF08321.12 EPE34558.1 - 3e-33 114.0 1.3 3e-33 114.0 1.3 1.7 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 EPE34558.1 - 1.5e-31 110.5 0.1 2.3e-31 109.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_2 PF07719.17 EPE34558.1 - 1e-12 47.1 4.4 0.0016 18.4 0.4 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EPE34558.1 - 8.3e-12 44.4 6.5 0.00043 20.0 0.3 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EPE34558.1 - 4.1e-06 26.4 9.3 0.00015 21.3 0.5 3.0 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.6 EPE34558.1 - 1e-05 25.6 0.7 0.011 15.9 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EPE34558.1 - 4.3e-05 24.1 5.8 0.061 14.0 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EPE34558.1 - 0.00018 21.9 0.8 0.023 15.3 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EPE34558.1 - 0.0042 17.2 5.1 1.1 9.7 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPE34558.1 - 0.01 16.3 3.5 1.1 9.8 0.1 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPE34558.1 - 0.062 14.2 1.3 11 7.1 0.1 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat adh_short PF00106.25 EPE34560.1 - 1.5e-25 89.8 0.0 2.2e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE34560.1 - 9.8e-18 64.6 0.0 1.9e-17 63.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE34560.1 - 6.2e-08 32.8 0.0 8.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE34560.1 - 2.9e-06 26.9 0.0 5.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE34560.1 - 0.0028 17.1 0.0 0.019 14.4 0.0 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EPE34560.1 - 0.051 13.5 0.0 0.082 12.8 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding LtuB PF17455.2 EPE34560.1 - 0.16 12.6 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 Late transcription unit B OMPdecase PF00215.24 EPE34561.1 - 4.1e-74 249.0 0.0 4.7e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MFS_1 PF07690.16 EPE34562.1 - 5.8e-37 127.4 54.4 7.5e-36 123.8 52.0 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Zn_peptidase_2 PF04298.12 EPE34562.1 - 0.023 14.1 0.0 0.14 11.5 0.0 2.4 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Ribosomal_L1 PF00687.21 EPE34563.1 - 5.4e-46 156.9 0.2 6.1e-46 156.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.18 EPE34563.1 - 0.1 11.3 0.1 0.14 10.8 0.1 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family Acyl-CoA_dh_1 PF00441.24 EPE34565.1 - 2.3e-32 112.3 1.1 3.4e-32 111.7 1.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EPE34565.1 - 6.3e-22 77.6 0.0 1.1e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EPE34565.1 - 1.6e-13 51.3 0.2 1.7e-12 48.0 0.0 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EPE34565.1 - 1.1e-07 32.3 0.1 1.9e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Skp1 PF01466.19 EPE34567.1 - 1.6e-29 101.7 0.4 3.3e-29 100.7 0.4 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EPE34567.1 - 2.5e-22 78.8 1.0 4.9e-22 77.9 0.6 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Trnau1ap PF17654.1 EPE34567.1 - 0.022 15.6 0.2 0.03 15.2 0.2 1.3 1 0 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins Arf PF00025.21 EPE34568.1 - 1.3e-66 223.4 0.0 1.5e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EPE34568.1 - 9.6e-12 45.2 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EPE34568.1 - 1.2e-08 34.8 0.0 1.5e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EPE34568.1 - 1.2e-08 34.6 0.0 1.6e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EPE34568.1 - 2.6e-07 30.1 0.1 5.8e-07 29.0 0.1 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 EPE34568.1 - 4.7e-06 26.1 0.0 6.1e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EPE34568.1 - 0.00059 19.9 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 EPE34568.1 - 0.0071 15.4 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 EPE34568.1 - 0.0076 15.8 0.0 0.045 13.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Catalase PF00199.19 EPE34569.1 - 1.1e-194 646.9 0.5 1.6e-194 646.3 0.5 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EPE34569.1 - 1.2e-11 44.6 0.0 3.2e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive 14-3-3 PF00244.20 EPE34570.1 - 1.6e-09 37.6 0.1 2.9e-08 33.5 0.0 2.0 2 0 0 2 2 2 2 14-3-3 protein CDC45 PF02724.14 EPE34571.1 - 1.1 7.5 33.2 0.14 10.4 16.2 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF2052 PF09747.9 EPE34571.1 - 4 7.5 32.0 0.37 10.9 13.3 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) MFS_1 PF07690.16 EPE34572.1 - 1.5e-39 135.9 55.4 6.3e-39 133.9 53.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE34572.1 - 5.5e-13 48.2 19.7 9.4e-13 47.4 19.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rhomboid PF01694.22 EPE34574.1 - 7.5e-08 32.5 10.0 1.2e-07 31.9 10.0 1.2 1 0 0 1 1 1 1 Rhomboid family ABC_tran PF00005.27 EPE34575.1 - 8.6e-15 55.5 0.1 2.2e-13 50.9 0.1 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EPE34575.1 - 1e-10 41.9 2.9 0.00019 21.4 0.8 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPE34575.1 - 0.0001 21.8 0.0 0.059 12.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF3584 PF12128.8 EPE34575.1 - 0.00087 17.0 0.2 0.0012 16.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 EPE34575.1 - 0.00088 19.0 0.1 0.0016 18.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 EPE34575.1 - 0.0066 16.2 0.0 0.0096 15.7 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 EPE34575.1 - 0.0091 16.5 0.1 0.013 16.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EPE34575.1 - 0.024 14.4 0.0 0.035 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EPE34575.1 - 0.038 14.2 0.3 0.062 13.6 0.3 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EPE34575.1 - 0.068 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EPE34575.1 - 0.094 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EPE34575.1 - 0.1 12.9 0.9 0.18 12.2 0.9 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.6 EPE34575.1 - 0.11 11.1 0.1 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EPE34575.1 - 0.12 11.8 0.2 0.22 11.0 0.2 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_22 PF13401.6 EPE34575.1 - 0.18 12.1 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EPE34575.1 - 0.23 11.1 0.0 0.31 10.6 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 EPE34575.1 - 0.24 11.5 0.3 0.45 10.6 0.3 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase WD40 PF00400.32 EPE34576.1 - 2e-29 101.2 31.3 2.4e-06 28.1 0.1 12.6 12 1 1 13 13 13 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE34576.1 - 5e-12 45.9 1.5 0.0022 18.3 0.2 6.7 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPE34576.1 - 0.0033 16.4 0.0 3 6.7 0.0 3.1 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4596 PF15363.6 EPE34576.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Abhydrolase_6 PF12697.7 EPE34578.1 - 6.2e-19 69.5 0.0 7.1e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Urm1 PF09138.11 EPE34579.1 - 3.2e-33 114.0 0.0 3.6e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) zf-C2H2 PF00096.26 EPE34580.1 - 1.4e-16 59.9 26.1 3.7e-05 23.9 0.3 4.8 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPE34580.1 - 1.2e-13 50.8 27.1 1.4e-08 34.7 0.8 4.9 5 0 0 5 5 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPE34580.1 - 1.3e-10 41.1 17.6 0.018 15.9 0.1 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EPE34580.1 - 0.0004 20.6 7.6 0.002 18.4 0.6 3.0 1 1 2 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 EPE34580.1 - 0.0013 18.9 6.4 0.13 12.4 0.2 3.3 2 1 1 3 3 3 1 Aberrant zinc-finger C1_4 PF07975.12 EPE34580.1 - 0.0058 16.8 5.6 0.43 10.9 0.3 2.6 2 0 0 2 2 2 2 TFIIH C1-like domain zf-LYAR PF08790.11 EPE34580.1 - 0.12 12.3 7.4 4.6 7.2 0.0 3.9 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 EPE34580.1 - 0.12 12.0 0.7 1.4 8.5 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_6 PF13912.6 EPE34580.1 - 0.31 11.1 9.1 8.2 6.6 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 EPE34580.1 - 0.46 11.0 8.0 67 4.1 0.1 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type GHMP_kinases_C PF08544.13 EPE34580.1 - 0.61 10.5 2.3 28 5.2 0.2 2.5 2 0 0 2 2 2 0 GHMP kinases C terminal zf-C2H2_11 PF16622.5 EPE34580.1 - 0.75 9.6 6.6 1.9 8.3 0.1 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type FOXP-CC PF16159.5 EPE34580.1 - 1.1 9.9 5.3 15 6.3 0.2 3.1 3 0 0 3 3 3 0 FOXP coiled-coil domain Zn-ribbon_8 PF09723.10 EPE34580.1 - 1.4 9.1 11.1 1.5 9.0 0.9 3.7 3 1 1 4 4 4 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 EPE34580.1 - 4.1 7.4 6.6 26 4.9 0.9 2.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Ribosomal_L5_C PF00673.21 EPE34582.1 - 6e-27 93.7 0.0 3e-26 91.4 0.0 2.0 2 1 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EPE34582.1 - 1.1e-12 48.1 0.0 2e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 UCH_1 PF13423.6 EPE34583.1 - 8e-21 74.9 0.0 5.2e-11 42.7 0.0 3.3 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF3398 PF11878.8 EPE34583.1 - 0.058 13.8 0.1 0.17 12.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) MARVEL PF01284.23 EPE34584.1 - 0.00032 20.8 22.2 0.00052 20.1 20.5 1.9 1 1 2 3 3 3 1 Membrane-associating domain FAD_binding_4 PF01565.23 EPE34586.1 - 1.4e-17 63.7 1.3 1.4e-17 63.7 1.3 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EPE34586.1 - 0.11 12.7 0.3 0.33 11.1 0.3 1.9 2 0 0 2 2 2 0 Berberine and berberine like Polbeta PF18765.1 EPE34587.1 - 0.098 12.8 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF2015 PF09435.10 EPE34588.1 - 1.1e-40 137.9 0.1 1.2e-40 137.8 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 EPE34589.1 - 3.1e-29 102.0 1.1 3.1e-29 102.0 1.1 1.4 1 1 1 2 2 2 1 Ribosomal L28e protein family Ldh_1_C PF02866.18 EPE34590.1 - 6e-48 162.9 0.0 8.6e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EPE34590.1 - 7.1e-43 146.1 0.1 1e-42 145.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EPE34590.1 - 0.038 13.0 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 EPE34590.1 - 0.11 12.0 0.2 12 5.4 0.2 2.3 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase TRAPP PF04051.16 EPE34591.1 - 6.2e-45 152.5 0.0 7.9e-45 152.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.32 EPE34592.1 - 2.4e-57 189.6 14.6 3.4e-09 37.2 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EPE34592.1 - 1.5e-16 60.4 6.2 3e-16 59.5 6.2 1.5 1 1 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EPE34592.1 - 4.2e-16 59.0 0.0 0.015 15.6 0.0 5.9 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EPE34592.1 - 6.6e-06 25.7 0.0 0.49 9.7 0.0 4.6 2 1 3 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 EPE34592.1 - 8.6e-06 24.9 0.1 1.5 7.7 0.0 5.5 2 2 4 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EPE34592.1 - 0.0017 17.0 0.4 0.048 12.2 0.1 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 EPE34592.1 - 0.06 13.3 0.0 22 5.2 0.0 4.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 EPE34592.1 - 0.089 12.1 0.0 19 4.5 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF3037 PF11236.8 EPE34592.1 - 0.11 12.9 0.1 0.22 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Nup160 PF11715.8 EPE34592.1 - 0.13 10.8 0.1 8.4 4.9 0.0 2.7 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Aspzincin_M35 PF14521.6 EPE34594.1 - 9.3e-07 29.5 0.0 1.8e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 EPE34594.1 - 0.02 13.8 0.1 0.04 12.8 0.0 1.5 2 0 0 2 2 2 0 Deuterolysin metalloprotease (M35) family Peptidase_U49 PF10463.9 EPE34594.1 - 0.028 14.2 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase U49 HECA PF15353.6 EPE34594.1 - 0.081 13.2 0.1 1.3 9.3 0.0 2.6 3 0 0 3 3 3 0 Headcase protein family homologue DUF2368 PF10166.9 EPE34595.1 - 0.072 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Lactamase_B PF00753.27 EPE34597.1 - 1.3e-17 64.5 0.3 4.1e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily HAGH_C PF16123.5 EPE34597.1 - 5.9e-15 55.5 0.1 1e-14 54.8 0.1 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B_2 PF12706.7 EPE34597.1 - 0.0015 18.0 0.3 0.026 14.0 0.3 2.6 1 1 1 2 2 2 1 Beta-lactamase superfamily domain DUF1236 PF06823.12 EPE34597.1 - 0.0076 16.1 0.2 0.57 10.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1236) DUF1264 PF06884.11 EPE34598.1 - 1.9e-79 265.2 0.1 2.2e-79 265.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) TauD PF02668.16 EPE34599.1 - 2.3e-47 162.1 0.3 2.9e-47 161.7 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Usp PF00582.26 EPE34600.1 - 2e-21 77.0 5.3 5.4e-21 75.6 1.3 3.0 2 1 0 2 2 2 1 Universal stress protein family Ribosomal_S7 PF00177.21 EPE34601.1 - 7.8e-26 90.5 0.0 1.3e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DND1_DSRM PF14709.7 EPE34602.1 - 0.0076 16.5 0.1 0.034 14.4 0.1 1.9 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 EPE34602.1 - 0.079 13.7 0.1 0.14 12.8 0.1 1.5 1 1 0 1 1 1 0 Double-stranded RNA binding motif NMO PF03060.15 EPE34603.1 - 5.3e-60 203.6 0.2 1e-59 202.6 0.2 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EPE34603.1 - 1.9e-14 53.4 0.0 1.2e-12 47.6 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EPE34603.1 - 0.002 17.2 0.1 0.0031 16.6 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 EPE34603.1 - 0.034 13.6 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Glu_synthase PF01645.17 EPE34603.1 - 0.037 13.2 0.2 0.094 11.8 0.2 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase Aldo_ket_red PF00248.21 EPE34604.1 - 3.3e-44 151.3 0.0 5.7e-44 150.5 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.22 EPE34605.1 - 4.2e-82 270.0 3.8 1.2e-22 79.5 0.3 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EPE34605.1 - 9.2e-28 96.2 0.5 3.6e-27 94.3 0.6 2.0 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 EPE34605.1 - 6.3e-06 26.2 0.5 1.5 9.0 0.0 5.3 4 2 0 4 4 4 1 RNA recognition motif RRM_occluded PF16842.5 EPE34605.1 - 0.0017 18.2 0.1 0.48 10.3 0.0 3.3 4 0 0 4 4 4 1 Occluded RNA-recognition motif CbiG_mid PF11761.8 EPE34605.1 - 0.0084 16.2 0.1 9.4 6.4 0.0 3.7 4 0 0 4 4 4 1 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.6 EPE34605.1 - 0.027 14.5 0.8 95 3.1 0.0 4.2 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif YflT PF11181.8 EPE34605.1 - 0.053 14.0 6.9 0.91 10.1 1.3 3.0 3 0 0 3 3 3 0 Heat induced stress protein YflT DEAD PF00270.29 EPE34606.1 - 4e-49 166.8 0.0 2.7e-48 164.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE34606.1 - 4.4e-31 107.5 0.0 1.3e-30 106.0 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE34606.1 - 1.9e-05 24.8 0.0 8.5e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EPE34606.1 - 0.0096 16.3 0.0 4.9 7.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain UTP25 PF06862.12 EPE34606.1 - 0.022 13.6 0.0 3 6.5 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Helicase_C_2 PF13307.6 EPE34606.1 - 0.067 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain His_Phos_2 PF00328.22 EPE34607.1 - 1e-26 94.2 0.0 1.3e-26 93.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PUF PF00806.19 EPE34608.1 - 2.1e-59 194.0 15.2 1.9e-08 33.6 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 EPE34608.1 - 0.022 14.6 1.1 48 3.8 0.0 4.5 4 1 1 5 5 5 0 Single Cache domain 2 CPL PF08144.11 EPE34608.1 - 0.045 14.1 8.2 11 6.3 1.7 4.2 1 1 2 3 3 3 0 CPL (NUC119) domain LOB PF03195.14 EPE34608.1 - 0.31 11.7 1.3 2.4 8.8 0.4 2.7 3 0 0 3 3 3 0 Lateral organ boundaries (LOB) domain LST1 PF05083.13 EPE34609.1 - 0.18 12.1 0.2 0.38 11.1 0.2 1.5 1 0 0 1 1 1 0 LST-1 protein Actin PF00022.19 EPE34610.1 - 3.1e-150 500.3 0.0 1.2e-149 498.3 0.0 1.7 1 1 0 1 1 1 1 Actin Abhydrolase_6 PF12697.7 EPE34612.1 - 2.2e-22 80.8 0.1 2.6e-22 80.5 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE34612.1 - 8e-16 58.5 0.0 1.5e-14 54.3 0.1 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE34612.1 - 2e-15 56.7 0.0 2.7e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EPE34612.1 - 6.4e-08 33.0 0.0 7.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 EPE34612.1 - 1.4e-06 27.2 0.0 2.9e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.13 EPE34612.1 - 9e-06 25.7 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EPE34612.1 - 4.2e-05 23.4 0.0 5.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.7 EPE34612.1 - 0.00042 19.3 0.0 0.00074 18.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 EPE34612.1 - 0.001 18.9 0.0 0.053 13.3 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EPE34612.1 - 0.0042 17.0 0.0 0.022 14.7 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_4 PF08386.10 EPE34612.1 - 0.013 15.6 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Lipase_3 PF01764.25 EPE34612.1 - 0.021 14.7 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) UPF0227 PF05728.12 EPE34612.1 - 0.06 13.3 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) LCAT PF02450.15 EPE34612.1 - 0.079 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DLH PF01738.18 EPE34612.1 - 0.08 12.5 0.0 8.6 5.8 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF900 PF05990.12 EPE34612.1 - 0.16 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) RF-1 PF00472.20 EPE34613.1 - 1.3e-22 79.9 2.2 2e-22 79.3 2.2 1.2 1 0 0 1 1 1 1 RF-1 domain SPT_ssu-like PF11779.8 EPE34614.1 - 9.7e-25 86.0 7.5 1.3e-24 85.6 7.5 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like CENP-I PF07778.11 EPE34615.1 - 1.9e-20 73.1 0.5 5.3e-11 41.9 0.1 2.6 1 1 1 2 2 2 2 Mis6 MA3 PF02847.17 EPE34615.1 - 0.056 13.4 0.1 0.18 11.8 0.1 1.9 2 0 0 2 2 2 0 MA3 domain ComK PF06338.11 EPE34616.1 - 0.0079 15.8 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 1 ComK protein APH PF01636.23 EPE34618.1 - 1.2e-11 45.1 0.0 3e-11 43.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE34618.1 - 0.00081 19.0 0.3 0.0021 17.7 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Patatin PF01734.22 EPE34619.1 - 7.8e-12 45.8 0.3 1.1e-10 42.0 0.3 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase LRR_4 PF12799.7 EPE34620.1 - 2.7 8.5 15.1 38 4.9 0.3 5.9 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) Rad9 PF04139.13 EPE34621.1 - 4.4e-34 118.1 0.1 5.9e-34 117.6 0.1 1.2 1 0 0 1 1 1 1 Rad9 RCC1 PF00415.18 EPE34622.1 - 7.7e-33 112.9 14.9 3.5e-08 33.9 0.1 6.8 6 1 1 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EPE34622.1 - 3.2e-18 65.0 28.0 4.4e-06 26.3 0.8 6.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Ribosomal_L30_N PF08079.12 EPE34623.1 - 1.9e-27 95.3 17.5 1.9e-27 95.3 17.5 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EPE34623.1 - 4.5e-17 61.7 2.6 9.9e-17 60.6 2.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Fe-S_biosyn PF01521.20 EPE34624.1 - 6.6e-15 55.3 0.0 4.9e-07 29.9 0.2 2.2 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis adh_short PF00106.25 EPE34625.1 - 1.9e-06 27.5 0.0 3.7e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE34625.1 - 9.3e-05 22.1 0.0 0.00016 21.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ATPgrasp_N PF18130.1 EPE34626.1 - 1.1e-14 54.7 0.1 2.8e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 EPE34626.1 - 5.3e-12 45.6 0.0 2.1e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EPE34626.1 - 5.3e-09 35.9 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 EPE34626.1 - 0.0014 18.2 0.0 0.0065 16.0 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 EPE34626.1 - 0.0075 16.3 0.0 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EPE34626.1 - 0.0085 15.9 0.0 0.022 14.5 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 EPE34626.1 - 0.025 14.3 0.1 12 5.7 0.0 2.9 3 0 0 3 3 3 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF4598 PF15370.6 EPE34627.1 - 5.7e-12 46.1 5.9 1.7e-11 44.6 0.7 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) RNA_pol_3_Rpc31 PF11705.8 EPE34627.1 - 1.1 9.4 11.1 2.1 8.6 9.0 2.5 1 1 1 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 EPE34627.1 - 8.7 6.0 11.9 7.5 6.2 0.6 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein IF4E PF01652.18 EPE34628.1 - 1.9e-38 131.7 0.1 2.4e-38 131.4 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Flagellin_N PF00669.20 EPE34628.1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region FA_hydroxylase PF04116.13 EPE34630.1 - 3.8e-26 92.0 12.9 3.8e-26 92.0 12.9 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily INCA1 PF15142.6 EPE34631.1 - 0.87 9.6 4.5 0.2 11.6 0.4 2.0 2 0 0 2 2 2 0 INCA1 Kinesin PF00225.23 EPE34632.1 - 6e-113 377.1 0.0 8.6e-113 376.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EPE34632.1 - 8.7e-27 93.9 0.0 1.9e-26 92.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF87 PF01935.17 EPE34632.1 - 0.011 15.8 5.3 0.75 9.8 0.0 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain UPF0449 PF15136.6 EPE34632.1 - 0.37 11.3 4.5 1.6 9.2 4.5 2.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Noggin PF05806.12 EPE34632.1 - 3.8 7.4 6.2 7.6 6.4 0.0 2.8 3 0 0 3 3 3 0 Noggin GDA1_CD39 PF01150.17 EPE34636.1 - 1.4e-100 337.0 0.0 1.7e-100 336.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PUL PF08324.11 EPE34637.1 - 4.2e-57 193.5 0.0 5.8e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 EPE34637.1 - 3.8e-35 120.9 0.0 6.3e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 EPE34637.1 - 1.5e-12 47.4 0.0 3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EPE34637.1 - 2.2e-05 24.9 0.1 0.0004 20.8 0.1 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EPE34637.1 - 0.00042 20.2 0.0 0.00075 19.4 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 EPE34637.1 - 0.0037 17.3 0.0 0.0088 16.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain OST3_OST6 PF04756.13 EPE34637.1 - 0.0061 15.9 0.0 0.0091 15.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EPE34637.1 - 0.021 14.7 0.0 0.078 12.9 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family AAA_lid_2 PF17863.1 EPE34638.1 - 3.3e-05 23.6 0.2 6.4e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 EPE34638.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ORC4_C PF14629.6 EPE34638.1 - 0.056 12.8 0.2 0.14 11.5 0.2 1.7 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Vps16_N PF04841.13 EPE34639.1 - 2.4e-98 329.6 0.0 3.2e-98 329.2 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EPE34639.1 - 5.3e-89 298.4 0.0 1e-88 297.5 0.0 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region SET PF00856.28 EPE34639.1 - 1.3e-12 48.4 0.1 6e-12 46.3 0.0 2.2 2 1 0 2 2 2 1 SET domain ANAPC4_WD40 PF12894.7 EPE34639.1 - 0.0054 17.0 0.0 1 9.7 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain TauD PF02668.16 EPE34640.1 - 6e-44 150.8 0.0 8.5e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ax_dynein_light PF10211.9 EPE34640.1 - 0.017 15.0 0.1 0.079 12.9 0.1 2.0 1 1 0 1 1 1 0 Axonemal dynein light chain CTNNBL PF08216.11 EPE34641.1 - 4.8e-40 135.9 0.0 1.9e-39 134.0 0.0 2.1 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear DUF3361 PF11841.8 EPE34641.1 - 0.00037 20.5 4.2 0.83 9.6 0.7 4.1 3 1 1 4 4 4 1 Domain of unknown function (DUF3361) SIL1 PF16782.5 EPE34641.1 - 0.0046 16.2 0.4 0.028 13.6 0.4 2.1 2 0 0 2 2 2 1 Nucleotide exchange factor SIL1 SH3-RhoG_link PF16609.5 EPE34641.1 - 0.019 14.7 0.3 0.034 13.9 0.3 1.3 1 0 0 1 1 1 0 SH3-RhoGEF linking unstructured region Mo25 PF08569.11 EPE34641.1 - 0.037 13.4 1.8 0.076 12.4 1.7 1.6 1 1 0 1 1 1 0 Mo25-like GP46 PF07409.12 EPE34641.1 - 0.043 13.6 0.7 0.11 12.2 0.2 1.9 2 0 0 2 2 2 0 Phage protein GP46 Arm PF00514.23 EPE34641.1 - 0.12 12.5 0.0 1.9 8.6 0.0 3.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat PMC2NT PF08066.12 EPE34641.1 - 0.13 13.0 4.4 36 5.1 0.0 4.2 4 0 0 4 4 4 0 PMC2NT (NUC016) domain Arm_3 PF16186.5 EPE34641.1 - 0.13 11.9 1.9 0.33 10.5 0.1 2.7 3 0 0 3 3 3 0 Atypical Arm repeat MFS_1 PF07690.16 EPE34642.1 - 6.9e-45 153.5 44.9 5.2e-41 140.7 30.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPE34642.1 - 1.5e-06 27.0 29.5 7.6e-06 24.7 3.9 3.7 2 2 2 4 4 4 3 MFS/sugar transport protein OATP PF03137.20 EPE34642.1 - 2.7e-06 26.0 2.1 0.0033 15.8 2.2 2.7 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 EPE34642.1 - 0.0032 16.8 13.1 0.0032 16.8 13.1 3.3 3 1 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 EPE34642.1 - 0.0078 14.7 0.8 0.0078 14.7 0.8 2.8 3 0 0 3 3 3 2 Transmembrane secretion effector MFS_1_like PF12832.7 EPE34642.1 - 0.029 13.2 17.3 0.027 13.4 7.2 3.2 2 1 1 3 3 3 0 MFS_1 like family Mem_trans PF03547.18 EPE34642.1 - 0.079 11.3 2.6 0.18 10.2 0.1 2.3 1 1 0 2 2 2 0 Membrane transport protein F-box PF00646.33 EPE34643.1 - 9.7e-08 31.7 0.0 3.3e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EPE34643.1 - 2.2e-05 24.2 0.0 4.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like YqgC PF17430.2 EPE34643.1 - 0.018 15.1 0.1 0.041 14.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized YqgC-like Cytochrome-c551 PF10643.9 EPE34643.1 - 0.12 11.9 0.3 0.21 11.1 0.3 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 TFB6 PF17110.5 EPE34645.1 - 1.4e-56 190.9 0.0 1.8e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH adh_short PF00106.25 EPE34646.1 - 4.5e-32 111.1 0.0 5.6e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE34646.1 - 4.3e-20 72.3 0.0 5.3e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE34646.1 - 4.9e-07 29.8 0.0 6.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE34646.1 - 5.1e-05 22.9 0.0 7.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPE34646.1 - 0.00023 21.1 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 EPE34646.1 - 0.096 12.0 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.20 EPE34646.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.18 EPE34647.1 - 6.2e-09 35.3 1.4 9.4e-09 34.7 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE34647.1 - 1.9e-07 31.1 10.8 1.9e-07 31.1 10.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 EPE34648.1 - 2.3e-110 369.5 20.4 2.8e-110 369.3 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE34648.1 - 4.5e-28 98.2 32.6 3.2e-27 95.4 24.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NDUF_B7 PF05676.13 EPE34650.1 - 1.2e-27 95.4 3.0 1.5e-27 95.1 3.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Asp_Glu_race PF01177.22 EPE34651.1 - 0.0016 18.3 0.0 0.0027 17.6 0.0 1.3 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Actin PF00022.19 EPE34652.1 - 8.1e-113 377.1 0.0 5.6e-112 374.3 0.0 1.8 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 EPE34652.1 - 0.029 13.5 0.2 0.082 12.1 0.1 1.7 2 0 0 2 2 2 0 Putative actin-like family MreB_Mbl PF06723.13 EPE34652.1 - 0.038 12.8 0.0 0.25 10.1 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein HAD_2 PF13419.6 EPE34653.1 - 6.7e-07 29.6 0.0 1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPE34653.1 - 0.00087 19.3 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EPE34653.1 - 0.062 13.6 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase UQ_con PF00179.26 EPE34654.1 - 4.3e-36 123.7 0.0 5.2e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_4 PF14555.6 EPE34655.1 - 0.0014 18.4 0.5 0.0027 17.5 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain DUF4665 PF15679.5 EPE34655.1 - 0.042 14.5 0.1 0.15 12.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) CUE PF02845.16 EPE34655.1 - 0.063 13.0 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 CUE domain TolA_bind_tri PF16331.5 EPE34655.1 - 0.34 11.0 2.8 5.7 7.1 0.2 2.9 3 0 0 3 3 3 0 TolA binding protein trimerisation NAD_kinase PF01513.21 EPE34656.1 - 6.9e-71 238.8 0.0 1.2e-70 238.1 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EPE34656.1 - 0.039 13.6 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain LRR_6 PF13516.6 EPE34657.1 - 0.45 10.7 2.3 10 6.5 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat CPP1-like PF11833.8 EPE34658.1 - 0.036 13.7 0.5 0.11 12.2 0.5 1.8 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like AhpC-TSA_2 PF13911.6 EPE34659.1 - 1.4e-15 57.4 0.1 3.9e-15 55.9 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EPE34659.1 - 0.00071 19.5 0.0 0.003 17.5 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family BAR PF03114.18 EPE34660.1 - 1.7e-68 230.9 6.0 2.1e-68 230.5 6.0 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EPE34660.1 - 6.3e-14 51.3 0.1 1.1e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPE34660.1 - 9.6e-12 44.6 0.1 1.6e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EPE34660.1 - 1.6e-08 34.1 0.0 3.8e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 EPE34660.1 - 0.0089 15.6 7.7 0.19 11.2 3.9 2.2 2 0 0 2 2 2 2 Vps5 C terminal like PAS_6 PF08348.11 EPE34660.1 - 0.057 13.3 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 YheO-like PAS domain BAR_3 PF16746.5 EPE34660.1 - 0.12 12.0 8.8 0.71 9.5 8.8 2.4 1 1 0 1 1 1 0 BAR domain of APPL family TMPIT PF07851.13 EPE34660.1 - 1.4 8.1 8.4 6.8 5.8 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein Aminotran_5 PF00266.19 EPE34661.1 - 1.2e-91 307.5 0.0 1.5e-91 307.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EPE34661.1 - 3e-07 30.0 0.0 4.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EPE34661.1 - 6.7e-06 25.6 0.1 1.1e-05 24.9 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EPE34661.1 - 0.00015 21.2 0.1 0.00026 20.4 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EPE34661.1 - 0.012 14.2 0.3 0.021 13.4 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme zf-RING_2 PF13639.6 EPE34662.1 - 5.1e-09 36.3 8.8 1e-08 35.3 8.8 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EPE34662.1 - 0.025 14.4 6.9 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 EPE34662.1 - 0.047 13.5 4.1 0.94 9.4 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_3 PF13920.6 EPE34662.1 - 0.052 13.4 10.3 0.2 11.5 10.6 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EPE34662.1 - 0.25 11.2 5.5 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EPE34662.1 - 0.31 11.0 7.4 0.54 10.3 7.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EPE34662.1 - 0.32 10.9 8.0 0.7 9.8 8.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EPE34662.1 - 0.39 10.9 9.6 0.82 9.9 7.0 2.5 1 1 1 2 2 2 0 FANCL C-terminal domain zf-rbx1 PF12678.7 EPE34662.1 - 4.5 7.6 10.1 36 4.7 10.3 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger domain Fungal_trans PF04082.18 EPE34663.1 - 2.1e-21 76.2 0.2 3.1e-21 75.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPE34663.1 - 2.2e-08 34.1 12.3 0.0012 19.2 3.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPE34663.1 - 4.1e-07 30.1 12.0 6.1e-07 29.6 6.3 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPE34663.1 - 0.00042 20.9 12.1 0.1 13.5 1.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE34663.1 - 0.075 13.3 2.6 0.77 10.1 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPE34663.1 - 1.8 9.1 4.6 0.57 10.7 0.9 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ank_5 PF13857.6 EPE34665.1 - 3.3e-10 40.0 0.1 5.4e-05 23.4 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE34665.1 - 1.1e-09 38.8 0.0 6.6e-09 36.2 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE34665.1 - 1.3e-09 37.5 0.0 4.9e-05 23.4 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EPE34665.1 - 2e-08 34.6 0.0 0.00022 21.7 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EPE34665.1 - 0.0039 17.6 1.0 0.21 12.1 0.1 3.6 4 0 0 4 4 4 1 Ankyrin repeat LAGLIDADG_2 PF03161.13 EPE34665.1 - 0.012 15.7 0.1 0.03 14.3 0.1 1.6 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family AAA_16 PF13191.6 EPE34665.1 - 0.021 15.2 0.0 0.045 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EPE34665.1 - 0.1 12.9 0.4 0.77 10.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain DUF676 PF05057.14 EPE34666.1 - 7.6e-05 22.3 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EPE34666.1 - 0.059 13.2 0.0 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Palmitoyl protein thioesterase Peptidase_M16_C PF05193.21 EPE34667.1 - 3.1e-54 183.8 0.0 1.6e-53 181.5 0.0 2.0 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EPE34667.1 - 3.8e-44 150.3 0.0 9.5e-43 145.7 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Disulph_isomer PF06491.11 EPE34667.1 - 0.0042 17.2 0.2 0.013 15.6 0.0 1.8 2 0 0 2 2 2 1 Disulphide isomerase FHA PF00498.26 EPE34668.1 - 4.1e-15 55.9 0.0 7.8e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EPE34668.1 - 3.1e-13 49.2 4.7 5.8e-13 48.3 4.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EPE34668.1 - 4.2e-05 23.8 10.7 7.2e-05 23.0 10.7 1.4 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 EPE34668.1 - 0.0019 18.4 0.0 0.0053 17.1 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 EPE34668.1 - 0.018 14.9 9.0 0.03 14.2 9.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE34668.1 - 0.09 12.8 5.5 0.2 11.6 5.6 1.6 1 1 0 1 1 1 0 zinc-RING finger domain PHD PF00628.29 EPE34668.1 - 0.18 11.8 5.6 0.34 10.8 5.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_2 PF13923.6 EPE34668.1 - 0.5 10.3 9.3 0.95 9.4 9.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE34668.1 - 0.51 10.4 10.0 1 9.5 10.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 EPE34668.1 - 1.1 9.4 4.3 1.9 8.6 4.3 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EPE34668.1 - 5.4 7.4 9.8 13 6.2 9.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Abhydrolase_4 PF08386.10 EPE34670.1 - 0.09 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein adh_short PF00106.25 EPE34671.1 - 1.8e-37 128.7 0.0 2.4e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE34671.1 - 1e-28 100.5 0.0 1.4e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE34671.1 - 4.6e-05 23.4 0.1 7.4e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 KR domain CRAL_TRIO PF00650.20 EPE34672.1 - 9e-39 132.7 0.0 1.2e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EPE34672.1 - 1.2e-14 54.2 0.2 2.6e-14 53.2 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain HTH_8 PF02954.19 EPE34672.1 - 0.04 13.7 0.2 0.079 12.8 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family TRAPP PF04051.16 EPE34673.1 - 9e-41 139.0 0.0 1.1e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ribosomal_S14 PF00253.21 EPE34674.1 - 1.4e-14 53.6 3.3 1.5e-14 53.5 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 EPE34674.1 - 0.018 14.9 0.4 0.023 14.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DUF3638 PF12340.8 EPE34675.1 - 1.4e-91 305.8 0.1 4.2e-91 304.3 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EPE34675.1 - 4e-16 58.1 0.0 9.3e-16 56.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) AA_permease PF00324.21 EPE34676.1 - 8.3e-143 476.4 38.3 1e-142 476.1 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE34676.1 - 8.3e-43 146.8 44.2 1.1e-42 146.4 44.2 1.0 1 0 0 1 1 1 1 Amino acid permease Pet100 PF09803.9 EPE34676.1 - 0.018 15.5 0.0 0.036 14.6 0.0 1.4 1 0 0 1 1 1 0 Pet100 Oxidored_molyb PF00174.19 EPE34677.1 - 5.6e-53 179.1 0.0 8.7e-53 178.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EPE34677.1 - 1.7e-24 86.4 1.8 6.9e-24 84.4 1.8 2.0 1 1 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 EPE34677.1 - 7.1e-11 42.1 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain OpcA PF07239.11 EPE34678.1 - 0.12 12.1 0.5 0.14 11.8 0.5 1.1 1 0 0 1 1 1 0 Outer membrane protein OpcA MIS13 PF08202.11 EPE34679.1 - 1.3e-51 175.7 4.5 1.3e-51 175.7 4.5 1.5 2 0 0 2 2 2 1 Mis12-Mtw1 protein family Mt_ATP-synt_D PF05873.12 EPE34679.1 - 0.0023 17.8 0.3 0.0052 16.6 0.3 1.6 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) CDRT4 PF15213.6 EPE34679.1 - 0.0062 17.1 1.3 0.0062 17.1 1.3 2.7 2 1 2 4 4 4 1 CMT1A duplicated region transcript 4 protein Methyltransf_16 PF10294.9 EPE34681.1 - 7.2e-22 77.9 0.0 1.3e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 EPE34681.1 - 8.6e-05 22.4 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 EPE34681.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EPE34681.1 - 0.0023 18.6 0.0 0.0067 17.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE34681.1 - 0.0023 18.6 0.0 0.011 16.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE34681.1 - 0.0023 17.8 0.0 0.0052 16.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EPE34681.1 - 0.012 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EPE34681.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EPE34681.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S24e PF01282.19 EPE34682.1 - 2e-34 117.4 0.1 3.9e-34 116.4 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e Pro_isomerase PF00160.21 EPE34684.1 - 1.3e-37 129.5 0.0 2e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EPE34684.1 - 7.4e-15 54.5 0.0 1.3e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 EPE34685.1 - 2.6e-08 33.8 5.0 4.3e-08 33.1 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S41 PF03572.18 EPE34687.1 - 7.4e-07 28.9 0.0 2.1e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 DUF4003 PF13170.6 EPE34687.1 - 0.057 12.8 0.4 0.094 12.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) HET PF06985.11 EPE34688.1 - 1.8e-31 109.5 1.0 3.2e-31 108.6 0.1 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) BST2 PF16716.5 EPE34688.1 - 0.0028 18.2 3.2 0.0064 17.1 3.2 1.6 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 DUF4449 PF14613.6 EPE34688.1 - 0.22 11.6 0.9 0.54 10.4 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) DLH PF01738.18 EPE34693.1 - 3.6e-18 65.9 0.0 4.2e-17 62.4 0.0 2.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EPE34693.1 - 0.018 14.9 0.0 0.55 10.1 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 EPE34693.1 - 0.076 11.5 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II RRP7 PF12923.7 EPE34694.1 - 8.4e-31 106.6 14.4 1.4e-30 105.9 14.4 1.3 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 EPE34694.1 - 6.7e-25 87.8 0.0 1.2e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain DUF5093 PF17011.5 EPE34694.1 - 0.0049 17.2 0.1 0.0049 17.2 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5093) YwqJ-deaminase PF14431.6 EPE34694.1 - 0.19 11.9 1.9 0.46 10.7 1.0 2.0 1 1 1 2 2 2 0 YwqJ-like deaminase peroxidase PF00141.23 EPE34695.1 - 7.9e-31 107.5 0.0 1.4e-30 106.7 0.0 1.4 1 1 0 1 1 1 1 Peroxidase Trypan_PARP PF05887.11 EPE34696.1 - 0.0048 16.9 19.7 0.017 15.1 19.7 1.9 1 1 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 EPE34696.1 - 5.8 6.0 10.0 0.49 9.5 4.2 2.0 2 1 0 2 2 2 0 Sperm equatorial segment protein 1 HET PF06985.11 EPE34697.1 - 5.7e-12 46.2 8.1 1.9e-09 38.0 2.3 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 EPE34697.1 - 2e-08 34.8 0.0 5.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EPE34697.1 - 8.4e-07 29.0 0.0 2.2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 EPE34697.1 - 0.014 14.6 1.2 0.029 13.6 0.6 1.6 1 1 1 2 2 2 0 KAP family P-loop domain APS_kinase PF01583.20 EPE34697.1 - 0.019 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 EPE34697.1 - 0.02 14.1 0.0 0.043 13.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 EPE34697.1 - 0.055 14.0 0.0 0.18 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EPE34697.1 - 0.062 13.7 0.1 0.22 11.9 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EPE34697.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 EPE34697.1 - 0.16 12.2 0.0 0.44 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EPE34697.1 - 0.18 11.5 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Med16 PF11635.8 EPE34698.1 - 0.19 9.6 0.4 0.25 9.2 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 Rad51 PF08423.11 EPE34699.1 - 2.3e-111 371.1 0.0 3.1e-111 370.7 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EPE34699.1 - 4.5e-12 46.0 0.1 6.2e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EPE34699.1 - 1.9e-09 38.0 1.8 3.7e-08 33.9 0.8 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 EPE34699.1 - 5.1e-09 35.8 0.0 1.1e-08 34.8 0.0 1.6 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 EPE34699.1 - 1.3e-07 31.4 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNA_pol_A_CTD PF03118.15 EPE34699.1 - 0.00027 20.6 0.5 0.0005 19.8 0.5 1.4 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain DnaB_C PF03796.15 EPE34699.1 - 0.004 16.5 1.3 1.2 8.4 0.2 2.9 2 1 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 EPE34699.1 - 0.0078 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EPE34699.1 - 0.088 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-CCHC PF00098.23 EPE34700.1 - 2.5e-44 147.4 60.1 7.8e-08 32.1 2.5 7.3 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EPE34700.1 - 1.2e-08 34.5 39.4 0.21 11.3 1.1 7.2 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 EPE34700.1 - 0.00013 21.6 43.5 0.0094 15.6 1.0 7.2 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 EPE34700.1 - 0.006 16.5 42.8 0.39 10.7 0.8 7.0 4 2 1 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.6 EPE34700.1 - 0.023 14.5 1.6 0.023 14.5 1.6 7.2 7 0 0 7 7 7 0 Zinc knuckle zf-CCHC_6 PF15288.6 EPE34700.1 - 0.24 11.3 0.3 0.24 11.3 0.3 6.9 6 1 1 7 7 7 0 Zinc knuckle Form_Nir_trans PF01226.17 EPE34701.1 - 0.028 13.8 0.0 0.038 13.3 0.0 1.1 1 0 0 1 1 1 0 Formate/nitrite transporter DUF1129 PF06570.11 EPE34701.1 - 0.19 11.2 0.4 0.27 10.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) WD40 PF00400.32 EPE34702.1 - 5.4e-38 128.3 9.6 9.6e-09 35.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE34702.1 - 1.6e-12 47.6 0.1 0.0042 17.4 0.0 4.9 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPE34702.1 - 0.033 13.1 0.0 12 4.7 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EPE34702.1 - 0.045 12.5 0.4 3.3 6.3 0.1 2.4 1 1 0 2 2 2 0 Nup133 N terminal like TRAPP PF04051.16 EPE34703.1 - 6.6e-35 120.0 0.1 8.3e-35 119.7 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 EPE34703.1 - 0.088 11.6 0.0 0.095 11.5 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A LisH PF08513.11 EPE34704.1 - 0.031 14.3 0.5 0.051 13.5 0.5 1.3 1 0 0 1 1 1 0 LisH zf-C2H2 PF00096.26 EPE34708.1 - 4.2e-08 33.2 8.3 0.068 13.7 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE34708.1 - 5.7e-05 23.6 2.8 0.88 10.6 0.2 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EPE34708.1 - 0.0014 18.8 1.0 15 5.7 0.1 3.1 3 0 0 3 3 3 2 Aberrant zinc-finger FOXP-CC PF16159.5 EPE34708.1 - 0.0035 17.9 8.4 2 9.1 0.0 3.4 3 0 0 3 3 3 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 EPE34708.1 - 0.13 12.6 1.7 2.8 8.3 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EPE34708.1 - 0.21 11.9 3.6 20 5.6 0.5 3.0 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 EPE34708.1 - 0.32 11.1 7.6 13 6.0 0.0 4.1 3 2 1 4 4 4 0 Zic proteins zinc finger domain DSBA PF01323.20 EPE34710.1 - 4.6e-19 69.0 0.0 2.8e-18 66.4 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain GRAS PF03514.14 EPE34710.1 - 0.14 11.1 0.0 0.29 10.0 0.0 1.4 2 0 0 2 2 2 0 GRAS domain family ADIP PF11559.8 EPE34712.1 - 1.1e-41 142.5 7.7 3.2e-41 140.9 7.7 1.9 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Fungal_trans_2 PF11951.8 EPE34712.1 - 0.00062 18.7 0.2 0.0017 17.2 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Retrotrans_gag PF03732.17 EPE34712.1 - 0.11 12.8 1.8 0.13 12.6 0.6 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein Laminin_II PF06009.12 EPE34712.1 - 0.41 10.7 6.9 1.4 8.9 6.9 1.9 1 0 0 1 1 1 0 Laminin Domain II TPR_MLP1_2 PF07926.12 EPE34712.1 - 2.9 8.0 13.5 0.33 11.0 6.6 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CCDC-167 PF15188.6 EPE34712.1 - 3.1 8.2 7.0 14 6.1 0.4 3.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Spc7 PF08317.11 EPE34712.1 - 4.3 6.1 9.4 0.59 8.9 4.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DLP_helical PF18709.1 EPE34712.1 - 8.1 5.5 9.5 1.9 7.6 2.8 2.3 1 1 1 2 2 2 0 Dynamin-like helical domain RTA1 PF04479.13 EPE34713.1 - 1.1e-71 240.7 14.7 1.1e-71 240.7 14.7 2.0 1 1 1 2 2 2 2 RTA1 like protein G0-G1_switch_2 PF15103.6 EPE34713.1 - 0.018 15.4 0.8 2.5 8.5 0.1 3.1 3 0 0 3 3 3 0 G0/G1 switch protein 2 DUF2177 PF09945.9 EPE34713.1 - 3 7.9 11.4 0.28 11.3 0.9 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2177) HisKA_7TM PF16927.5 EPE34713.1 - 3.2 7.7 24.8 13 5.7 24.8 1.9 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase HET PF06985.11 EPE34714.1 - 4.4e-27 95.2 0.9 9.7e-27 94.1 0.9 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Palm_thioest PF02089.15 EPE34715.1 - 5.1e-07 29.8 0.0 2.6e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EPE34715.1 - 2.4e-06 27.2 0.0 4.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EPE34715.1 - 1.5e-05 24.8 0.0 3.4e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 EPE34715.1 - 0.00045 19.9 0.0 0.0012 18.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 EPE34715.1 - 0.0022 17.3 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EPE34715.1 - 0.013 16.1 0.0 0.02 15.5 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.12 EPE34715.1 - 0.015 14.9 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Mst1_SARAH PF11629.8 EPE34715.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 Hydrolase_4 PF12146.8 EPE34715.1 - 0.2 10.9 0.0 0.57 9.4 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF915 PF06028.11 EPE34715.1 - 0.2 10.9 0.0 0.44 9.8 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.18 EPE34715.1 - 0.23 10.9 0.0 0.65 9.5 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 2) V-ATPase_G PF03179.15 EPE34716.1 - 4.6e-28 97.8 14.4 5.2e-28 97.6 14.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF16 PF01519.16 EPE34716.1 - 0.043 14.3 8.2 0.042 14.3 7.6 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF87 PF01935.17 EPE34716.1 - 0.048 13.8 2.4 0.055 13.5 2.4 1.0 1 0 0 1 1 1 0 Helicase HerA, central domain V-ATPase_G_2 PF16999.5 EPE34716.1 - 0.16 12.4 11.2 0.52 10.8 11.2 1.8 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit SAPS PF04499.15 EPE34716.1 - 0.24 10.1 7.2 0.25 10.1 7.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HOIP-UBA PF16678.5 EPE34716.1 - 0.47 10.4 5.8 0.92 9.5 5.8 1.4 1 1 1 2 2 2 0 HOIP UBA domain pair RRF PF01765.19 EPE34716.1 - 1 9.3 13.3 1.5 8.7 13.3 1.4 1 0 0 1 1 1 0 Ribosome recycling factor Trypan_glycop PF00913.19 EPE34716.1 - 1 8.5 10.2 1.2 8.3 10.2 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) PET117 PF15786.5 EPE34717.1 - 8.6e-25 86.8 2.3 1e-24 86.6 2.3 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial RNA_pol_Rpb2_6 PF00562.28 EPE34718.1 - 1.9e-124 415.7 0.2 6.1e-124 414.0 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EPE34718.1 - 3.6e-62 209.5 0.0 9.9e-62 208.1 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EPE34718.1 - 3.7e-46 157.2 0.0 6.1e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EPE34718.1 - 2e-32 111.4 0.1 4.9e-32 110.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EPE34718.1 - 9.7e-26 89.8 1.2 1.7e-25 88.9 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EPE34718.1 - 1.3e-23 83.1 1.9 2.1e-23 82.4 0.9 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EPE34718.1 - 1.7e-20 73.3 0.0 1.7e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 ADH_N PF08240.12 EPE34719.1 - 3.3e-25 88.1 7.7 5.3e-25 87.4 7.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE34719.1 - 1.7e-17 63.6 0.0 3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE34719.1 - 3.5e-06 28.1 0.0 5.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EPE34719.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EPE34719.1 - 0.0079 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EPE34719.1 - 0.058 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pex24p PF06398.11 EPE34721.1 - 9.3e-91 304.5 0.6 1.6e-90 303.8 0.6 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 EPE34721.1 - 0.011 14.2 3.6 0.056 11.8 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) Reticulon PF02453.17 EPE34721.1 - 0.038 13.9 1.7 0.15 12.0 1.7 1.9 1 1 1 2 2 2 0 Reticulon Pkinase PF00069.25 EPE34722.1 - 2.4e-51 174.7 0.1 4.5e-51 173.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE34722.1 - 3.1e-20 72.5 0.0 5e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPE34722.1 - 0.056 13.4 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE34722.1 - 0.059 12.9 0.2 0.14 11.7 0.2 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase COesterase PF00135.28 EPE34723.1 - 2.2e-73 247.9 0.0 3.6e-73 247.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE34723.1 - 5.6e-10 39.4 0.3 2.3e-09 37.4 0.1 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Helo_like_N PF17111.5 EPE34724.1 - 0.054 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins YqzH PF14164.6 EPE34725.1 - 0.93 9.6 4.9 1.9 8.6 4.9 1.4 1 0 0 1 1 1 0 YqzH-like protein Sugar_tr PF00083.24 EPE34726.1 - 1.4e-87 294.5 23.2 1.9e-87 294.0 23.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE34726.1 - 3.3e-11 42.7 41.4 4.4e-09 35.7 30.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DHHA1 PF02272.19 EPE34727.1 - 0.0036 17.7 0.0 17 5.8 0.0 4.1 4 1 1 5 5 5 1 DHHA1 domain DUF4985 PF16373.5 EPE34727.1 - 0.062 13.8 0.1 1.1e+02 3.3 0.0 4.4 1 1 4 5 5 5 0 Domain of unknown function ADK_lid PF05191.14 EPE34727.1 - 0.91 9.6 25.3 23 5.1 0.0 7.0 6 2 0 6 6 6 0 Adenylate kinase, active site lid YyzF PF14116.6 EPE34727.1 - 1.6 8.8 17.4 52 4.0 0.1 6.4 7 0 0 7 7 7 0 YyzF-like protein Inv-AAD PF18785.1 EPE34727.1 - 4.1 7.3 8.8 0.56 10.1 0.3 3.0 1 1 1 3 3 3 0 Invertebrate-AID/APOBEC-deaminase Sugar_tr PF00083.24 EPE34728.1 - 7.3e-70 236.1 22.0 8.5e-70 235.8 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE34728.1 - 2.5e-15 56.3 35.6 1.2e-14 54.0 29.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPE34728.1 - 8.5e-08 31.2 18.5 4.9e-06 25.4 3.3 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EPE34728.1 - 4.7e-06 25.7 9.0 0.0002 20.3 4.2 2.2 2 0 0 2 2 2 2 MFS_1 like family Phage_holin_7_1 PF16081.5 EPE34728.1 - 0.26 11.5 1.7 0.61 10.3 1.7 1.6 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family BRI3BP PF14965.6 EPE34728.1 - 3.6 7.0 11.2 1.6 8.2 6.0 2.3 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Beta-lactamase PF00144.24 EPE34729.1 - 1.5e-41 142.7 0.0 2.3e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 EPE34729.1 - 0.031 13.7 0.0 0.057 12.8 0.0 1.4 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase AAA PF00004.29 EPE34730.1 - 1.2e-17 64.5 0.0 2.9e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE34730.1 - 0.00019 21.9 0.0 0.00038 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPE34730.1 - 0.0095 16.2 0.3 0.083 13.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EPE34730.1 - 0.01 15.8 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zot PF05707.12 EPE34730.1 - 0.038 13.6 0.1 0.3 10.7 0.1 2.2 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_33 PF13671.6 EPE34730.1 - 0.054 13.7 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EPE34730.1 - 0.062 13.6 0.1 0.25 11.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EPE34730.1 - 0.072 13.1 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EPE34730.1 - 0.095 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NRN1 PF15056.6 EPE34731.1 - 0.3 11.2 1.4 18 5.5 0.2 3.4 3 1 0 3 3 3 0 Neuritin protein family Abhydrolase_6 PF12697.7 EPE34732.1 - 5.8e-11 43.4 0.0 7.2e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE34732.1 - 5.3e-06 25.9 0.0 8.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE34732.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ndr PF03096.14 EPE34732.1 - 0.036 12.8 0.0 0.058 12.1 0.0 1.3 1 0 0 1 1 1 0 Ndr family LIDHydrolase PF10230.9 EPE34732.1 - 0.24 10.9 0.0 0.39 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Fructosamin_kin PF03881.14 EPE34733.1 - 8.8e-27 94.0 0.0 4.2e-26 91.8 0.0 1.7 1 1 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EPE34733.1 - 0.056 13.4 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family adh_short PF00106.25 EPE34734.1 - 6.9e-29 100.7 0.2 1.1e-28 100.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE34734.1 - 5e-23 81.9 0.1 6.6e-23 81.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE34734.1 - 6.7e-09 35.9 0.1 9.5e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EPE34734.1 - 0.0038 16.4 0.2 0.0057 15.9 0.2 1.4 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EPE34734.1 - 0.0042 16.6 0.0 0.0081 15.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_5 PF00941.21 EPE34734.1 - 0.11 12.2 0.0 0.68 9.6 0.0 2.0 1 1 1 2 2 2 0 FAD binding domain in molybdopterin dehydrogenase Fungal_trans PF04082.18 EPE34735.1 - 9.4e-24 83.9 0.0 7.3e-23 80.9 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE34735.1 - 3.5e-05 23.8 12.1 5.5e-05 23.2 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IHABP4_N PF16174.5 EPE34735.1 - 0.16 12.6 3.8 0.28 11.8 3.8 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Amidase PF01425.21 EPE34736.1 - 1.1e-90 304.8 0.0 1.5e-89 301.1 0.0 1.9 1 1 0 1 1 1 1 Amidase Transp_cyt_pur PF02133.15 EPE34737.1 - 1.4e-103 347.0 36.2 1.8e-103 346.7 36.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PTR2 PF00854.21 EPE34738.1 - 1.1e-92 310.9 8.1 2e-92 310.1 8.1 1.4 1 0 0 1 1 1 1 POT family AAA PF00004.29 EPE34739.1 - 3.4e-15 56.7 0.0 6.4e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPE34739.1 - 0.00078 19.7 0.2 0.024 14.9 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EPE34739.1 - 0.003 18.0 0.0 0.0066 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EPE34739.1 - 0.061 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IPT PF01745.16 EPE34739.1 - 0.092 12.1 0.0 15 4.9 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase AAA_11 PF13086.6 EPE34739.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4806 PF16064.5 EPE34739.1 - 0.13 12.5 0.0 0.56 10.5 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4806) ABM PF03992.16 EPE34740.1 - 0.046 13.8 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase UPF1_Zn_bind PF09416.10 EPE34741.1 - 9.6e-71 236.7 1.9 1.6e-70 236.0 0.8 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EPE34741.1 - 9.7e-60 201.6 0.0 1.8e-59 200.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EPE34741.1 - 3.1e-54 184.5 2.9 9.6e-31 107.5 0.3 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EPE34741.1 - 1.4e-31 108.6 0.0 2.7e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EPE34741.1 - 7.3e-14 51.9 0.1 5.1e-13 49.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPE34741.1 - 3.3e-11 43.7 0.0 1.6e-10 41.5 0.1 2.1 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 EPE34741.1 - 7.7e-06 26.0 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 EPE34741.1 - 8.7e-05 22.4 0.3 0.38 10.4 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EPE34741.1 - 0.00047 19.5 0.0 0.016 14.5 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 EPE34741.1 - 0.00092 19.1 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 EPE34741.1 - 0.0015 17.8 0.0 0.51 9.4 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.21 EPE34741.1 - 0.0029 17.2 0.0 0.027 14.0 0.0 2.0 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 EPE34741.1 - 0.0052 16.6 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_10 PF12846.7 EPE34741.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ATPase PF06745.13 EPE34741.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 EPE34741.1 - 0.052 13.8 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EPE34741.1 - 0.14 11.6 0.0 0.38 10.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Brix PF04427.18 EPE34742.1 - 4.3e-30 105.3 0.1 5.5e-30 104.9 0.1 1.1 1 0 0 1 1 1 1 Brix domain EamA PF00892.20 EPE34743.1 - 1.7e-12 47.7 22.1 3.5e-06 27.2 14.4 2.5 2 0 0 2 2 2 2 EamA-like transporter family CSG2 PF16965.5 EPE34743.1 - 6e-06 25.5 11.6 1.3e-05 24.4 9.4 2.3 2 1 0 2 2 2 1 Ceramide synthase regulator Nuc_sug_transp PF04142.15 EPE34743.1 - 0.0017 17.6 7.8 0.022 13.9 7.7 2.0 1 1 0 1 1 1 1 Nucleotide-sugar transporter IncD PF17628.2 EPE34743.1 - 6.2 6.6 6.0 53 3.6 3.4 2.8 2 1 0 2 2 2 0 Inclusion membrane protein D SGL PF08450.12 EPE34744.1 - 0.0048 16.5 0.0 0.014 15.0 0.1 1.7 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region GMC_oxred_N PF00732.19 EPE34745.1 - 8.3e-28 97.6 0.0 1.1e-27 97.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE34745.1 - 6e-07 30.1 0.0 1.6e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EPE34745.1 - 0.0089 15.1 0.1 0.017 14.2 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EPE34745.1 - 0.019 14.6 0.9 0.043 13.4 0.5 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE34745.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EPE34745.1 - 0.063 12.1 0.0 0.13 11.1 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 EPE34745.1 - 0.075 12.2 0.0 0.35 10.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE34745.1 - 0.078 12.0 0.1 0.77 8.8 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 EPE34745.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family RTA1 PF04479.13 EPE34746.1 - 1.5e-58 197.8 6.5 1.5e-58 197.8 6.5 1.4 2 0 0 2 2 2 1 RTA1 like protein Zn_clus PF00172.18 EPE34747.1 - 0.00018 21.6 11.1 0.00037 20.5 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE34747.1 - 0.0019 17.1 0.6 0.0029 16.5 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 EPE34748.1 - 1.4e-21 77.2 0.0 2.1e-21 76.6 0.0 1.2 1 1 0 1 1 1 1 FAD binding domain DUF496 PF04363.12 EPE34749.1 - 0.018 15.0 0.2 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF496) CBM65_1 PF18259.1 EPE34749.1 - 0.82 9.8 3.6 32 4.7 0.1 3.1 3 0 0 3 3 3 0 Carbohydrate binding module 65 domain 1 DUF2075 PF09848.9 EPE34751.1 - 1.6e-44 152.6 0.0 2.2e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) MazG-like PF12643.7 EPE34751.1 - 3.3e-13 49.7 0.1 8.5e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 MazG-like family ResIII PF04851.15 EPE34751.1 - 4.6e-05 23.5 0.0 0.0021 18.1 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit MazG PF03819.17 EPE34751.1 - 0.00033 20.8 0.1 0.00077 19.6 0.1 1.6 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain GIY-YIG PF01541.24 EPE34751.1 - 0.00046 20.4 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain AAA PF00004.29 EPE34751.1 - 0.01 16.2 0.1 0.18 12.2 0.0 2.8 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EPE34751.1 - 0.011 15.5 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EPE34751.1 - 0.015 15.7 0.1 0.14 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 EPE34751.1 - 0.024 15.0 0.0 0.23 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EPE34751.1 - 0.025 14.9 0.7 0.45 10.8 0.3 3.0 1 1 1 2 2 2 0 AAA domain ATPase PF06745.13 EPE34751.1 - 0.064 12.6 0.6 0.33 10.3 0.2 2.1 1 1 1 2 2 2 0 KaiC IstB_IS21 PF01695.17 EPE34751.1 - 0.091 12.5 0.0 0.76 9.5 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 EPE34751.1 - 0.099 12.5 0.5 0.54 10.2 0.6 2.3 2 1 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 EPE34751.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DEAD PF00270.29 EPE34751.1 - 0.18 11.5 0.9 3 7.6 0.1 2.9 2 1 2 4 4 4 0 DEAD/DEAH box helicase KorB PF08535.10 EPE34752.1 - 0.15 12.2 0.0 8 6.6 0.0 2.7 2 0 0 2 2 2 0 KorB domain NUDIX PF00293.28 EPE34753.1 - 1.4e-13 51.0 0.1 4.9e-13 49.3 0.1 1.8 2 0 0 2 2 2 1 NUDIX domain Lipase_3 PF01764.25 EPE34753.1 - 0.0029 17.5 0.0 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) NUDIX_4 PF14815.6 EPE34753.1 - 0.064 13.3 0.1 0.86 9.6 0.0 2.6 2 1 0 2 2 2 0 NUDIX domain Glyco_hydro_127 PF07944.12 EPE34755.1 - 1.3e-128 429.8 1.1 1.5e-128 429.6 1.1 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Fungal_trans PF04082.18 EPE34757.1 - 2.9e-20 72.4 0.2 4.3e-20 71.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE34757.1 - 2.9e-08 33.7 11.8 5e-08 32.9 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 EPE34758.1 - 2e-24 85.6 0.2 4.1e-24 84.6 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE34758.1 - 1.5e-17 63.8 0.1 2.7e-17 63.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EPE34758.1 - 1.8e-08 34.2 1.0 0.00024 20.7 0.5 2.4 1 1 1 2 2 2 2 Glucose dehydrogenase C-terminus ThiF PF00899.21 EPE34758.1 - 0.0048 16.3 0.7 0.0086 15.5 0.7 1.3 1 0 0 1 1 1 1 ThiF family ApbA PF02558.16 EPE34758.1 - 0.013 15.2 0.1 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 EPE34758.1 - 0.044 13.0 0.3 0.099 11.9 0.2 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EPE34758.1 - 0.061 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TOBE_2 PF08402.10 EPE34758.1 - 0.078 13.2 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 TOBE domain FAD_binding_3 PF01494.19 EPE34758.1 - 0.095 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 EPE34758.1 - 0.11 12.1 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 EPE34758.1 - 0.14 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Aldedh PF00171.22 EPE34759.1 - 4.9e-151 503.4 1.7 6.7e-151 502.9 1.7 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldo_ket_red PF00248.21 EPE34759.1 - 1.3e-26 93.5 0.1 2.7e-25 89.2 0.1 2.2 1 1 0 1 1 1 1 Aldo/keto reductase family NAD_binding_8 PF13450.6 EPE34759.1 - 5.5e-11 42.5 0.0 1.5e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EPE34759.1 - 2.9e-09 36.6 0.1 4.2e-08 32.8 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EPE34759.1 - 8.2e-08 31.1 0.4 4.6e-06 25.3 0.2 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EPE34759.1 - 2.1e-06 27.1 0.3 0.00017 20.9 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EPE34759.1 - 0.0002 20.7 0.0 0.012 14.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE34759.1 - 0.0026 17.4 0.0 0.055 13.1 0.0 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EPE34759.1 - 0.046 13.7 0.3 0.29 11.1 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.17 EPE34759.1 - 0.078 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family adh_short_C2 PF13561.6 EPE34760.1 - 3e-55 187.4 0.0 3.6e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE34760.1 - 3.5e-45 153.9 0.0 4.3e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE34760.1 - 8.4e-12 45.4 0.0 1.7e-11 44.4 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF4372 PF14294.6 EPE34761.1 - 0.0091 16.1 0.1 8.9 6.5 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4372) Glyco_hydro_59 PF02057.15 EPE34762.1 - 2.1e-11 43.6 0.6 3.1e-11 43.1 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 EPE34762.1 - 1.6e-10 41.0 3.6 5.3e-10 39.4 3.6 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydr_30_2 PF14587.6 EPE34762.1 - 4.4e-09 36.4 3.5 5.6e-09 36.1 0.0 2.4 2 1 0 2 2 2 1 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.16 EPE34762.1 - 1.8e-06 27.2 0.1 2.8e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Bcr-Abl_Oligo PF09036.10 EPE34763.1 - 0.048 13.7 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Sec2p PF06428.11 EPE34763.1 - 5.8 7.0 10.7 8.2 6.5 7.3 2.6 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p AATF-Che1 PF13339.6 EPE34764.1 - 0.092 13.4 2.6 6.2 7.5 1.0 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Amidohydro_1 PF01979.20 EPE34765.1 - 2.8e-22 79.5 0.2 2.6e-18 66.5 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EPE34765.1 - 1.9e-14 54.0 0.2 3.4e-11 43.3 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family Fungal_trans PF04082.18 EPE34766.1 - 1.6e-06 27.4 5.8 0.00043 19.4 5.8 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain HSDR_N_2 PF13588.6 EPE34767.1 - 0.099 12.7 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF3573 PF12097.8 EPE34767.1 - 0.29 9.9 1.2 0.54 9.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) p450 PF00067.22 EPE34768.1 - 2.8e-43 148.3 0.0 4.5e-43 147.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Parathyroid PF01279.17 EPE34768.1 - 0.051 14.2 0.0 0.13 12.9 0.0 1.7 1 0 0 1 1 1 0 Parathyroid hormone family adh_short_C2 PF13561.6 EPE34769.1 - 4.2e-40 137.7 0.6 1.1e-39 136.4 0.6 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE34769.1 - 6.7e-33 113.8 0.9 4.4e-32 111.1 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EPE34769.1 - 8.5e-07 29.0 3.1 2.1e-06 27.8 0.5 2.1 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EPE34769.1 - 0.00054 19.2 0.1 0.00078 18.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EPE34769.1 - 0.0054 16.2 0.6 0.011 15.1 0.1 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EPE34769.1 - 0.012 15.1 0.6 0.079 12.4 0.6 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 EPE34769.1 - 0.015 15.7 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF1776 PF08643.10 EPE34769.1 - 0.044 13.2 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ApbA PF02558.16 EPE34769.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EPE34769.1 - 0.12 12.2 0.2 0.23 11.3 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EPE34769.1 - 0.12 11.3 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AAT PF03417.16 EPE34770.1 - 5.3e-28 98.2 0.0 6.7e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase MFS_1 PF07690.16 EPE34771.1 - 3.6e-33 115.0 30.5 2.3e-32 112.3 30.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EPE34771.1 - 0.00041 19.8 16.3 0.00087 18.7 9.9 2.4 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF1129 PF06570.11 EPE34771.1 - 0.011 15.3 0.2 0.011 15.3 0.2 3.5 2 2 3 5 5 5 0 Protein of unknown function (DUF1129) Amidohydro_1 PF01979.20 EPE34772.1 - 1.7e-14 53.9 0.0 3.3e-14 52.9 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPE34772.1 - 0.079 12.4 0.0 0.47 9.9 0.0 1.9 1 1 0 1 1 1 0 Amidohydrolase family Fungal_trans PF04082.18 EPE34773.1 - 2.3e-10 39.9 0.5 6.8e-10 38.4 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE34773.1 - 1.2e-05 25.3 10.5 2.2e-05 24.5 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 EPE34774.1 - 2.2e-101 339.9 16.9 2.9e-101 339.6 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE34774.1 - 1.3e-29 103.3 47.0 6.7e-27 94.3 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EPE34774.1 - 3.5e-07 28.9 0.4 3.5e-07 28.9 0.4 2.9 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family FAD_binding_3 PF01494.19 EPE34775.1 - 6.3e-08 32.2 3.6 2.3e-06 27.1 3.6 2.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE34775.1 - 7.7e-05 22.1 0.5 0.013 14.7 0.2 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EPE34775.1 - 0.007 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 EPE34775.1 - 0.0085 15.0 1.5 4.6 6.0 0.0 3.0 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 EPE34775.1 - 0.016 15.5 1.0 0.049 13.9 0.3 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE34775.1 - 0.022 14.3 2.0 0.035 13.7 1.4 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EPE34775.1 - 0.062 13.9 0.9 0.17 12.4 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE34775.1 - 0.071 12.1 0.6 0.44 9.5 0.6 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EPE34775.1 - 0.092 12.0 0.1 0.43 9.8 0.5 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 EPE34775.1 - 0.094 12.0 0.3 0.16 11.2 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EPE34775.1 - 0.1 11.7 0.0 0.32 10.0 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.14 EPE34775.1 - 0.1 11.2 1.0 0.17 10.6 0.3 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 EPE34775.1 - 0.12 12.3 0.2 2 8.4 0.3 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pkinase PF00069.25 EPE34776.1 - 3.2e-14 52.9 0.0 4.8e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE34776.1 - 2e-08 33.9 0.0 2.7e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPE34776.1 - 0.00017 21.6 0.0 0.00025 21.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EPE34776.1 - 0.024 14.3 0.0 0.063 12.9 0.0 1.7 1 1 1 2 2 2 0 RIO1 family Choline_kinase PF01633.20 EPE34776.1 - 0.044 13.4 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EPE34776.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HATPase_c_3 PF13589.6 EPE34777.1 - 1.7e-18 66.8 0.0 4.7e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 EPE34777.1 - 5.2e-10 39.3 0.0 5.2e-09 36.0 0.0 2.3 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 EPE34777.1 - 0.003 18.0 0.0 0.0092 16.5 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Bact_transglu_N PF08379.10 EPE34777.1 - 0.041 14.8 0.1 0.2 12.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial transglutaminase-like N-terminal region Cu-oxidase PF00394.22 EPE34779.1 - 6.4e-34 117.4 0.0 1.7e-29 103.0 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EPE34779.1 - 5e-29 100.7 1.1 6e-28 97.3 0.0 2.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EPE34779.1 - 1.8e-23 82.8 5.0 3.9e-21 75.2 0.5 3.4 2 1 0 2 2 2 2 Multicopper oxidase Glyco_hydro_76 PF03663.14 EPE34780.1 - 8.5e-36 124.2 18.9 1.1e-35 123.8 18.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF4817 PF16087.5 EPE34780.1 - 0.16 11.8 0.1 0.39 10.6 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) P5CR_dimer PF14748.6 EPE34781.1 - 6.7e-25 87.3 0.1 1.9e-24 85.9 0.0 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EPE34781.1 - 6e-12 46.0 0.4 1.9e-11 44.4 0.4 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1996 PF09362.10 EPE34782.1 - 2.1e-81 273.4 0.1 3e-81 272.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Kelch_5 PF13854.6 EPE34783.1 - 2.6e-11 43.3 13.8 2.1e-10 40.3 0.5 5.2 6 0 0 6 6 6 1 Kelch motif Kelch_6 PF13964.6 EPE34783.1 - 3.4e-06 27.1 13.7 0.44 10.9 0.2 5.8 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 EPE34783.1 - 0.00034 20.5 18.2 0.23 11.5 0.4 5.9 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EPE34783.1 - 0.0091 16.3 16.7 0.074 13.4 0.6 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain CYYR1 PF10873.8 EPE34783.1 - 0.027 14.9 0.1 0.079 13.4 0.1 1.7 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Kelch_1 PF01344.25 EPE34783.1 - 0.036 13.7 11.9 6.8 6.4 0.0 6.3 7 0 0 7 7 7 0 Kelch motif DUF3172 PF11371.8 EPE34783.1 - 0.1 12.3 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) Kelch_2 PF07646.15 EPE34783.1 - 1.2 9.3 7.9 66 3.7 0.0 5.3 5 0 0 5 5 5 0 Kelch motif SprT-like PF10263.9 EPE34786.1 - 5.3e-05 23.1 0.5 0.00018 21.3 0.0 2.1 2 1 0 2 2 2 1 SprT-like family adh_short PF00106.25 EPE34789.1 - 7.7e-21 74.4 0.0 2.6e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE34789.1 - 1.3e-11 44.6 0.0 4.5e-07 29.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE34789.1 - 6.6e-09 35.9 0.0 1.3e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 KR domain CENP-N PF05238.13 EPE34790.1 - 1.5e-139 465.9 0.0 1.7e-139 465.7 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like p450 PF00067.22 EPE34792.1 - 1.1e-69 235.4 0.0 1.7e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EPE34792.1 - 2.4e-29 102.4 21.5 2.4e-29 102.4 21.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE34792.1 - 3e-11 42.9 1.1 3e-11 42.9 1.1 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EPE34792.1 - 0.00013 20.6 2.5 0.00021 19.9 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAA_hydrolase PF01557.18 EPE34793.1 - 3.3e-55 187.1 0.0 4e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EPE34793.1 - 4.1e-08 33.4 0.0 7.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal FAD_binding_3 PF01494.19 EPE34794.1 - 1.5e-20 73.8 0.0 2.7e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.11 EPE34794.1 - 4.9e-14 52.5 0.0 8.7e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.14 EPE34794.1 - 3e-10 39.8 0.2 5.3e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE34794.1 - 6.7e-07 29.5 0.1 1.6e-06 28.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE34794.1 - 1.9e-06 27.2 0.7 3e-06 26.6 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPE34794.1 - 8.9e-06 25.5 1.4 2.6e-05 24.0 1.1 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EPE34794.1 - 4.8e-05 22.9 0.4 7.7e-05 22.2 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EPE34794.1 - 0.00014 20.9 0.1 0.019 13.8 0.1 2.3 1 1 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 EPE34794.1 - 0.00033 19.9 0.0 0.00056 19.1 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EPE34794.1 - 0.0012 17.6 0.7 0.0025 16.6 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EPE34794.1 - 0.0021 17.4 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EPE34794.1 - 0.0029 16.7 1.1 0.014 14.5 1.1 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 EPE34794.1 - 0.0081 16.7 0.2 0.025 15.1 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EPE34794.1 - 0.012 14.9 0.7 0.83 8.9 0.1 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EPE34794.1 - 0.023 14.0 0.2 0.076 12.3 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 EPE34794.1 - 0.065 12.9 0.4 0.16 11.6 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 EPE34794.1 - 0.069 12.4 2.2 0.11 11.7 0.1 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 EPE34794.1 - 0.32 9.7 1.0 2.9 6.6 0.2 2.1 1 1 1 2 2 2 0 MCRA family Aldedh PF00171.22 EPE34796.1 - 2.4e-06 26.4 0.0 0.011 14.2 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Fungal_trans PF04082.18 EPE34797.1 - 1.4e-09 37.4 0.1 2.7e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPE34797.1 - 3.5e-07 30.3 14.6 0.0026 18.1 3.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE34797.1 - 3e-06 27.6 11.8 0.0038 17.9 2.4 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_clus PF00172.18 EPE34797.1 - 0.00043 20.3 10.5 0.00043 20.3 10.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 EPE34797.1 - 0.00048 20.4 12.6 0.013 15.9 4.8 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 EPE34797.1 - 0.005 16.6 6.0 0.038 13.7 0.2 2.8 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 EPE34797.1 - 0.035 14.1 10.1 0.17 11.9 1.7 3.3 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE34797.1 - 0.07 13.4 6.8 2.1 8.7 1.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 EPE34797.1 - 0.096 12.6 0.6 1.2 9.0 0.2 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) LigB PF02900.18 EPE34798.1 - 3.5e-17 62.4 0.0 4e-17 62.2 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PepX_C PF08530.10 EPE34799.1 - 2.5e-47 161.7 0.2 3.9e-47 161.1 0.2 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 EPE34799.1 - 9.7e-41 140.1 0.1 1.4e-40 139.6 0.1 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EPE34799.1 - 0.071 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 IN_DBD_C PF00552.21 EPE34799.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Integrase DNA binding domain Cupin_2 PF07883.11 EPE34800.1 - 4.5e-08 32.7 0.1 7.2e-07 28.8 0.0 2.1 1 1 1 2 2 2 1 Cupin domain Cupin_3 PF05899.12 EPE34800.1 - 0.0015 18.1 0.4 0.14 11.9 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF861) Bac_rhamnosid6H PF17389.2 EPE34801.1 - 2.8e-10 40.0 0.1 3.5e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain F-box PF00646.33 EPE34802.1 - 0.00035 20.4 0.7 0.001 18.9 0.7 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPE34802.1 - 0.0071 16.2 0.1 0.0071 16.2 0.1 2.1 2 0 0 2 2 2 1 F-box-like Pro_CA PF00484.19 EPE34804.1 - 9.8e-21 74.7 0.0 1.2e-20 74.4 0.0 1.0 1 0 0 1 1 1 1 Carbonic anhydrase RSN1_7TM PF02714.15 EPE34805.1 - 2.9e-92 308.9 19.5 2.9e-92 308.9 19.5 2.0 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EPE34805.1 - 1.6e-43 148.2 0.5 1.6e-43 148.2 0.5 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EPE34805.1 - 1.9e-31 109.7 0.8 3.3e-31 108.9 0.8 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EPE34805.1 - 2.9e-22 78.6 0.2 9.4e-22 77.0 0.0 1.9 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter APG6_N PF17675.1 EPE34805.1 - 0.31 11.6 1.2 0.65 10.5 1.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region CN_hydrolase PF00795.22 EPE34806.1 - 3.5e-28 98.7 0.0 2.6e-27 95.8 0.0 2.0 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase TatD_DNase PF01026.21 EPE34808.1 - 2.4e-55 187.7 0.0 2.8e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Hydrolase PF00702.26 EPE34808.1 - 0.18 12.1 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase bZIP_2 PF07716.15 EPE34809.1 - 1.2e-11 44.4 10.6 2e-11 43.8 10.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EPE34809.1 - 0.0046 17.0 10.9 0.012 15.7 10.9 1.7 1 1 0 1 1 1 1 bZIP transcription factor XhlA PF10779.9 EPE34809.1 - 0.0068 16.6 3.2 0.014 15.5 3.2 1.5 1 0 0 1 1 1 1 Haemolysin XhlA LCD1 PF09798.9 EPE34809.1 - 0.013 14.1 0.1 0.013 14.1 0.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein ATG16 PF08614.11 EPE34809.1 - 0.018 15.3 5.5 0.018 15.3 5.5 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TSC22 PF01166.18 EPE34809.1 - 0.038 14.3 0.3 0.07 13.4 0.3 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Fib_alpha PF08702.10 EPE34809.1 - 0.17 12.0 1.9 0.3 11.3 1.9 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APC_u14 PF16635.5 EPE34809.1 - 0.62 10.6 5.6 0.56 10.8 4.2 1.7 1 1 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr HET PF06985.11 EPE34810.1 - 6.1e-24 85.0 0.0 1.6e-23 83.7 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4470 PF14737.6 EPE34811.1 - 3.4e-07 30.4 1.0 1.6e-06 28.2 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) Gpr1_Fun34_YaaH PF01184.19 EPE34812.1 - 1.6e-28 99.7 30.1 2e-28 99.4 30.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MAGP PF05507.11 EPE34816.1 - 0.11 12.9 1.5 0.31 11.4 0.7 2.0 1 1 1 2 2 2 0 Microfibril-associated glycoprotein (MAGP) Pkinase PF00069.25 EPE34820.1 - 2.9e-05 23.6 0.0 4.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF5089 PF17002.5 EPE34822.1 - 0.0081 16.1 0.9 0.013 15.4 0.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) Chorismate_synt PF01264.21 EPE34825.1 - 1.3e-137 457.9 0.0 1.5e-137 457.7 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase BPL_LplA_LipB PF03099.19 EPE34826.1 - 1.2e-05 25.3 0.0 4e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Zip PF02535.22 EPE34828.1 - 3.9e-58 197.2 4.6 7.8e-58 196.3 4.6 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter DUF456 PF04306.13 EPE34828.1 - 1 9.6 12.7 4.7 7.5 7.6 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF456) PNP_phzG_C PF10590.9 EPE34829.1 - 1.8e-20 72.7 2.8 1.8e-20 72.7 2.8 2.5 2 1 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EPE34829.1 - 7.9e-19 67.6 0.0 1.2e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 EPE34829.1 - 0.0015 19.1 0.6 0.0035 17.9 0.6 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_C12 PF01088.21 EPE34830.1 - 5.6e-56 189.6 0.0 7e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 CBM_1 PF00734.18 EPE34831.1 - 1.3e-07 31.4 11.6 1.3e-07 31.4 11.6 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain adh_short PF00106.25 EPE34833.1 - 6e-19 68.3 0.4 1.4e-17 63.8 0.3 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE34833.1 - 1.2e-09 38.0 0.1 2.6e-09 37.0 0.1 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE34833.1 - 4.4e-06 26.7 0.3 6.9e-06 26.1 0.3 1.3 1 0 0 1 1 1 1 KR domain FTR PF01913.18 EPE34833.1 - 0.14 12.1 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Ank_2 PF12796.7 EPE34834.1 - 5.4e-36 123.0 6.8 8.9e-16 58.3 0.5 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE34834.1 - 7.3e-21 74.3 0.2 2.2e-10 40.9 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE34834.1 - 2.3e-18 64.4 1.5 7.6e-05 22.8 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EPE34834.1 - 1.3e-15 57.0 2.6 0.0029 18.0 0.1 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EPE34834.1 - 2.8e-14 53.0 2.0 0.00011 22.4 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) bZIP_2 PF07716.15 EPE34834.1 - 0.0054 16.8 1.5 0.009 16.1 1.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EPE34834.1 - 0.017 15.2 4.5 0.028 14.5 4.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_Maf PF03131.17 EPE34834.1 - 0.068 13.7 1.7 0.12 12.9 1.7 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor adh_short PF00106.25 EPE34835.1 - 5.7e-20 71.6 0.0 9.5e-17 61.1 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE34835.1 - 7.8e-14 51.8 0.0 4.4e-10 39.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE34835.1 - 1.7e-08 34.6 0.0 2.7e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 KR domain IMPDH PF00478.25 EPE34835.1 - 0.00027 20.0 0.0 0.00038 19.6 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Epimerase PF01370.21 EPE34835.1 - 0.00036 20.1 0.2 0.0015 18.0 0.1 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EPE34835.1 - 0.023 14.9 0.4 0.22 11.8 0.3 2.3 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Hexapep PF00132.24 EPE34836.1 - 2.6e-13 49.1 14.5 2.2e-07 30.3 5.0 3.5 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EPE34836.1 - 1.4e-10 40.7 17.6 2e-08 33.8 5.4 3.6 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 EPE34836.1 - 6.3e-08 32.7 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase DUF1681 PF07933.14 EPE34840.1 - 4.6e-59 198.4 0.0 6.6e-59 197.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Tom5 PF10642.9 EPE34840.1 - 0.42 10.7 2.2 4.2 7.5 0.3 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase IF-2B PF01008.17 EPE34841.1 - 2.5e-49 168.0 0.0 3e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Oxidored_molyb PF00174.19 EPE34842.1 - 1.7e-49 167.8 0.0 3.2e-49 166.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EPE34842.1 - 2.4e-22 79.5 2.5 4.6e-22 78.5 2.5 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain UpxZ PF06603.11 EPE34843.1 - 0.0026 18.0 0.9 0.09 13.1 0.2 3.1 3 0 0 3 3 3 1 UpxZ family of transcription anti-terminator antagonists V_ATPase_I PF01496.19 EPE34843.1 - 1.5 6.6 7.2 1.6 6.6 7.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 EPE34843.1 - 2.2 6.7 4.9 3.3 6.1 4.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF724 PF05266.14 EPE34843.1 - 6.1 6.6 21.5 0.12 12.2 14.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Pyr_redox_2 PF07992.14 EPE34844.1 - 1.6e-43 149.0 0.0 4.3e-43 147.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE34844.1 - 6.7e-13 49.0 1.1 2.8e-09 37.4 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EPE34844.1 - 7.4e-07 28.3 0.2 8.7e-06 24.9 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EPE34844.1 - 6.1e-05 22.6 0.1 0.00023 20.8 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EPE34844.1 - 0.00059 19.2 0.9 0.0017 17.8 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EPE34844.1 - 0.0016 18.9 0.1 0.0043 17.5 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.6 EPE34844.1 - 0.29 10.3 0.3 2.2 7.5 0.3 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CLTH PF10607.9 EPE34845.1 - 1.7e-32 112.4 0.0 2.3e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EPE34845.1 - 3.1e-09 36.5 0.0 5.4e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 LisH PRK PF00485.18 EPE34846.1 - 6.8e-61 205.4 0.0 1.1e-60 204.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 EPE34846.1 - 2.4e-45 154.5 0.0 3.7e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 EPE34846.1 - 3.6e-05 24.3 0.0 7.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 EPE34846.1 - 0.0001 22.2 0.0 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 EPE34846.1 - 0.00019 21.6 0.0 0.0011 19.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 EPE34846.1 - 0.0014 19.1 0.1 0.021 15.3 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_17 PF13207.6 EPE34846.1 - 0.0019 18.6 1.1 0.022 15.2 0.2 2.7 2 1 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 EPE34846.1 - 0.012 15.3 0.0 0.21 11.3 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase Zeta_toxin PF06414.12 EPE34846.1 - 0.021 14.1 0.0 0.048 12.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 EPE34846.1 - 0.03 14.1 0.3 0.071 12.9 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 EPE34846.1 - 0.038 14.1 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain NB-ARC PF00931.22 EPE34846.1 - 0.041 13.1 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 EPE34846.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EPE34846.1 - 0.079 12.9 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 EPE34846.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DSPc PF00782.20 EPE34848.1 - 5.2e-19 68.4 0.0 6.2e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EPE34848.1 - 0.0014 18.2 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EPE34848.1 - 0.1 12.5 0.3 0.88 9.5 0.3 2.1 1 1 0 1 1 1 0 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 EPE34848.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain Lipase_3 PF01764.25 EPE34849.1 - 1.3e-08 34.8 0.0 2.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DLH PF01738.18 EPE34849.1 - 0.016 14.7 0.0 0.097 12.2 0.0 1.9 1 1 1 2 2 2 0 Dienelactone hydrolase family PGAP1 PF07819.13 EPE34849.1 - 0.044 13.5 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein BaxI_1 PF12811.7 EPE34850.1 - 0.43 10.1 8.6 2.5 7.6 2.8 2.9 2 1 1 3 3 3 0 Bax inhibitor 1 like Flavi_DEAD PF07652.14 EPE34851.1 - 0.00096 19.1 1.3 0.49 10.3 0.1 2.2 2 0 0 2 2 2 2 Flavivirus DEAD domain TRCF PF03461.15 EPE34851.1 - 0.0017 18.7 0.5 0.8 10.1 0.0 3.1 3 0 0 3 3 3 1 TRCF domain DUF4252 PF14060.6 EPE34851.1 - 0.0027 17.6 5.9 0.3 11.0 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4252) DUF2325 PF10087.9 EPE34851.1 - 0.048 13.8 0.3 8.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) DNA_pol3_a_NI PF14480.6 EPE34851.1 - 0.068 13.2 0.0 4.6 7.3 0.0 2.6 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus I DUF3042 PF11240.8 EPE34851.1 - 0.12 12.4 0.2 15 5.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) AAA_lid_6 PF17866.1 EPE34851.1 - 0.14 12.4 0.1 12 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA lid domain DUF1358 PF07096.11 EPE34851.1 - 0.15 12.1 0.0 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1358) TUDOR PF00567.24 EPE34851.1 - 0.17 11.9 0.8 37 4.4 0.0 3.2 3 0 0 3 3 3 0 Tudor domain S-antigen PF05756.11 EPE34851.1 - 3.7 8.0 5.5 5.1 7.5 0.1 3.1 3 1 1 4 4 4 0 S-antigen protein SNRNP27 PF08648.12 EPE34851.1 - 6.2 7.0 9.0 12 6.0 1.3 2.5 2 0 0 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins zf-C2H2_4 PF13894.6 EPE34853.1 - 6.1e-05 23.5 15.2 0.00051 20.7 0.6 4.9 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.26 EPE34853.1 - 0.00086 19.6 1.0 0.00086 19.6 1.0 3.9 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-met PF12874.7 EPE34853.1 - 0.023 15.1 0.1 0.023 15.1 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EPE34853.1 - 0.045 13.8 0.1 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Homez PF11569.8 EPE34853.1 - 0.049 13.1 0.2 0.12 11.9 0.2 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez zf-C2H2_jaz PF12171.8 EPE34853.1 - 0.1 12.9 0.3 0.1 12.9 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Actin_micro PF17003.5 EPE34853.1 - 0.26 10.4 1.1 0.59 9.3 1.1 1.6 1 1 0 1 1 1 0 Putative actin-like family zf-C2H2_2 PF12756.7 EPE34853.1 - 0.42 11.0 9.0 19 5.7 6.0 3.5 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Zf_RING PF16744.5 EPE34853.1 - 2.6 8.2 6.2 0.25 11.5 0.6 2.2 2 0 0 2 2 2 0 KIAA1045 RING finger MFS_1 PF07690.16 EPE34854.1 - 3.1e-46 157.9 32.0 5e-46 157.2 32.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE34854.1 - 1.8e-09 37.0 12.3 1.8e-09 37.0 12.3 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter FA_desaturase PF00487.24 EPE34854.1 - 1 9.1 18.4 0.033 14.0 1.7 3.5 3 1 1 4 4 4 0 Fatty acid desaturase OTU PF02338.19 EPE34855.1 - 2.9e-22 79.5 0.0 7.2e-22 78.2 0.0 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EPE34855.1 - 0.0011 18.5 0.1 0.31 10.5 0.0 2.5 2 1 1 3 3 3 2 Peptidase C65 Otubain DUF572 PF04502.13 EPE34855.1 - 0.46 10.1 17.9 0.55 9.8 17.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) HAT_KAT11 PF08214.11 EPE34855.1 - 3.8 6.7 6.6 6 6.0 6.6 1.3 1 0 0 1 1 1 0 Histone acetylation protein Lipoprotein_2 PF00921.17 EPE34855.1 - 7.4 6.0 16.7 9.2 5.7 16.7 1.3 1 1 0 1 1 1 0 Borrelia lipoprotein Hamartin PF04388.12 EPE34855.1 - 9.1 4.8 10.8 11 4.5 10.8 1.0 1 0 0 1 1 1 0 Hamartin protein TPMT PF05724.11 EPE34856.1 - 6.3e-27 94.6 0.0 8.1e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 EPE34856.1 - 1.3e-06 28.4 0.0 1.7e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE34856.1 - 4.5e-05 24.1 0.0 9.8e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE34856.1 - 7.9e-05 23.3 0.0 0.00016 22.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE34856.1 - 0.00024 21.7 0.0 0.00045 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE34856.1 - 0.0015 18.4 0.0 0.0065 16.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain UBM PF14377.6 EPE34856.1 - 0.012 15.0 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin binding region AdoMet_MTase PF07757.13 EPE34856.1 - 0.088 13.2 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase N2227 PF07942.12 EPE34856.1 - 0.21 10.7 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein adh_short_C2 PF13561.6 EPE34857.1 - 1.5e-46 158.8 0.0 1.9e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE34857.1 - 2.7e-43 147.7 0.0 3.5e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE34857.1 - 7e-07 29.3 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Lycopene_cycl PF05834.12 EPE34857.1 - 0.15 11.1 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein AMP-binding PF00501.28 EPE34858.1 - 2.3e-73 247.2 0.0 3e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EPE34858.1 - 9.8e-19 67.0 0.5 3.6e-18 65.2 0.5 2.1 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EPE34858.1 - 1.5e-17 64.3 0.1 1.3e-15 58.1 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ank_2 PF12796.7 EPE34859.1 - 2.1e-57 191.7 7.9 1.3e-10 41.7 0.2 8.0 3 2 5 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE34859.1 - 1.4e-41 140.3 10.2 1.4e-06 28.7 0.1 11.6 5 2 7 12 12 12 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE34859.1 - 1.6e-34 114.0 12.1 0.02 15.4 0.0 15.6 16 0 0 16 16 16 8 Ankyrin repeat Ank PF00023.30 EPE34859.1 - 1.4e-27 94.9 24.6 0.047 14.1 0.0 14.9 16 0 0 16 16 16 8 Ankyrin repeat Ank_5 PF13857.6 EPE34859.1 - 9.5e-24 83.2 20.0 0.0012 19.1 0.1 12.2 8 4 4 12 12 12 6 Ankyrin repeats (many copies) Clr5 PF14420.6 EPE34859.1 - 4.8e-18 65.1 4.6 8e-18 64.4 2.7 2.2 2 0 0 2 2 2 1 Clr5 domain DUF3734 PF12536.8 EPE34859.1 - 0.16 12.3 0.0 1.3 9.4 0.0 2.5 3 0 0 3 3 3 0 Patatin phospholipase SHMT PF00464.19 EPE34861.1 - 3.7e-194 644.9 0.0 4.3e-194 644.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Ribosomal_L19e PF01280.20 EPE34862.1 - 2.5e-61 206.0 5.8 2.5e-61 206.0 5.8 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e Gcn1_N PF12074.8 EPE34863.1 - 1.5e-124 415.9 5.1 1.5e-124 415.9 5.1 4.2 4 0 0 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT_EZ PF13513.6 EPE34863.1 - 4.3e-33 113.3 30.4 5.5e-07 30.0 0.0 18.5 16 5 5 21 21 19 7 HEAT-like repeat HEAT PF02985.22 EPE34863.1 - 8.1e-33 109.7 29.0 0.12 12.7 0.1 20.7 23 0 0 23 23 21 7 HEAT repeat HEAT_2 PF13646.6 EPE34863.1 - 5.4e-25 87.6 42.6 1.5e-05 25.3 0.1 15.8 10 4 7 18 18 18 7 HEAT repeats Cnd1 PF12717.7 EPE34863.1 - 1.2e-14 54.7 6.2 0.43 10.6 0.4 10.5 7 3 3 10 10 10 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EPE34863.1 - 3.1e-14 53.3 0.2 2.6 8.7 0.0 9.7 8 4 4 12 12 11 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EPE34863.1 - 1.3e-11 43.8 5.2 0.066 11.8 0.0 8.9 8 2 2 10 10 10 3 Adaptin N terminal region ParcG PF10274.9 EPE34863.1 - 6.2e-10 39.5 3.4 0.0017 18.5 0.0 6.1 6 1 1 7 7 6 2 Parkin co-regulated protein CLASP_N PF12348.8 EPE34863.1 - 3.2e-07 30.2 0.0 5.4 6.5 0.0 6.9 5 1 3 8 8 8 2 CLASP N terminal FANCI_S2 PF14676.6 EPE34863.1 - 1.5e-05 25.3 0.3 0.43 10.9 0.0 4.9 4 0 0 4 4 3 1 FANCI solenoid 2 TIP120 PF08623.10 EPE34863.1 - 7.8e-05 22.5 0.0 0.022 14.6 0.0 4.8 4 2 2 6 6 5 1 TATA-binding protein interacting (TIP20) RasGEF_N_2 PF14663.6 EPE34863.1 - 0.00036 20.9 2.4 0.83 10.1 0.0 5.3 6 0 0 6 6 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF937 PF06078.11 EPE34863.1 - 0.00068 20.3 10.4 6.3 7.4 0.0 7.3 5 1 0 6 6 6 1 Bacterial protein of unknown function (DUF937) MMS19_C PF12460.8 EPE34863.1 - 0.0014 17.8 30.4 0.059 12.5 0.1 8.0 7 1 2 9 9 9 4 RNAPII transcription regulator C-terminal Ecm29 PF13001.7 EPE34863.1 - 0.0023 16.7 1.7 42 2.6 0.0 6.0 5 2 1 6 6 6 0 Proteasome stabiliser TFCD_C PF12612.8 EPE34863.1 - 0.0048 16.7 1.7 0.048 13.5 0.0 3.7 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal Tti2 PF10521.9 EPE34863.1 - 0.0097 15.5 3.6 0.74 9.3 0.0 5.4 7 0 0 7 7 6 1 Tti2 family Mo25 PF08569.11 EPE34863.1 - 0.047 13.1 0.0 16 4.7 0.0 3.7 4 1 0 4 4 4 0 Mo25-like RTP1_C1 PF10363.9 EPE34863.1 - 0.19 11.9 7.8 56 4.0 0.0 7.1 8 0 0 8 8 6 0 Required for nuclear transport of RNA pol II C-terminus 1 U3snoRNP10 PF12397.8 EPE34863.1 - 0.6 10.5 8.2 49 4.3 0.0 6.3 6 1 0 6 6 5 0 U3 small nucleolar RNA-associated protein 10 RIX1 PF08167.12 EPE34863.1 - 0.83 9.4 7.4 1.3 8.7 0.1 5.0 5 1 1 6 6 6 0 rRNA processing/ribosome biogenesis HA2 PF04408.23 EPE34864.1 - 4.9e-16 59.0 0.5 1.5e-15 57.4 0.0 2.2 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EPE34864.1 - 4.2e-13 49.6 0.0 1.1e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPE34864.1 - 1.4e-11 44.5 0.1 2.9e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EPE34864.1 - 1.5e-08 35.0 0.2 2.6e-07 31.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.16 EPE34864.1 - 2.6e-07 30.9 0.0 6.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_29 PF13555.6 EPE34864.1 - 0.0016 18.1 0.0 0.0048 16.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EPE34864.1 - 0.0025 18.3 0.1 0.015 15.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_19 PF13245.6 EPE34864.1 - 0.0055 17.1 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EPE34864.1 - 0.014 14.8 0.1 0.037 13.4 0.0 1.7 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 EPE34864.1 - 0.045 13.7 0.3 0.16 11.9 0.3 2.0 1 1 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 EPE34864.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 EPE34864.1 - 0.55 10.7 0.0 0.55 10.7 0.0 2.9 4 0 0 4 4 3 0 AAA domain Epimerase PF01370.21 EPE34865.1 - 1.2e-14 54.3 0.0 2e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE34865.1 - 2.5e-12 46.4 0.0 7.9e-12 44.8 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EPE34865.1 - 3.5e-06 26.7 0.0 3.1e-05 23.6 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 EPE34865.1 - 2e-05 23.9 0.0 0.00042 19.6 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EPE34865.1 - 6.3e-05 22.5 0.7 0.00025 20.6 0.1 2.2 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EPE34865.1 - 0.00017 20.8 0.2 0.00027 20.2 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EPE34865.1 - 0.00039 19.9 1.6 0.042 13.3 0.2 2.4 2 1 0 2 2 2 2 short chain dehydrogenase GCHY-1 PF02649.14 EPE34866.1 - 0.56 9.7 3.1 1.3 8.5 3.0 1.6 1 1 0 1 1 1 0 Type I GTP cyclohydrolase folE2 Mcp5_PH PF12814.7 EPE34867.1 - 4.7e-47 159.1 0.0 1.1e-46 158.0 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 EPE34867.1 - 0.036 14.5 14.5 0.079 13.4 13.8 1.9 2 0 0 2 2 2 0 Fez1 STAT_alpha PF01017.20 EPE34867.1 - 0.59 10.0 6.4 1.1 9.1 6.4 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain DivIC PF04977.15 EPE34867.1 - 1.1 9.1 3.4 1.3 8.9 1.9 1.9 1 1 0 1 1 1 0 Septum formation initiator GAS PF13851.6 EPE34867.1 - 2.1 7.6 12.6 4.3 6.6 12.6 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMCO5 PF14992.6 EPE34867.1 - 4 6.9 8.2 7.9 6.0 8.2 1.4 1 0 0 1 1 1 0 TMCO5 family Cnn_1N PF07989.11 EPE34867.1 - 8.2 6.7 8.3 1.3 9.2 2.7 2.3 1 1 0 2 2 2 0 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 EPE34867.1 - 9.2 6.3 17.7 3.6 7.6 4.6 2.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HAD_2 PF13419.6 EPE34868.1 - 1.9e-08 34.6 0.0 2.9e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPE34868.1 - 6.8e-07 29.8 0.0 9.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPE34868.1 - 7.9e-06 25.8 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HET PF06985.11 EPE34871.1 - 1.3e-28 100.1 0.3 2.4e-28 99.3 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PALP PF00291.25 EPE34872.1 - 9.9e-60 202.4 1.7 1.4e-59 202.0 1.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Transglut_core PF01841.19 EPE34872.1 - 0.012 16.1 0.1 0.021 15.2 0.1 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily DFP PF04127.15 EPE34872.1 - 0.11 12.3 0.3 0.18 11.6 0.3 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PEP-utilizers PF00391.23 EPE34872.1 - 1.2 8.9 4.1 0.73 9.6 0.9 2.1 2 0 0 2 2 2 0 PEP-utilising enzyme, mobile domain IlvN PF07991.12 EPE34873.1 - 8.9e-47 158.7 0.1 1.4e-46 158.1 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EPE34873.1 - 2e-40 138.4 0.1 3.5e-40 137.6 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.17 EPE34873.1 - 0.0067 17.0 0.0 0.018 15.6 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EPE34873.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Chitin_synth_1 PF01644.17 EPE34874.1 - 2.8e-69 232.3 0.0 4.4e-69 231.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase UQ_con PF00179.26 EPE34874.1 - 6.7e-37 126.3 0.0 1.1e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_1N PF08407.11 EPE34874.1 - 2.8e-27 94.4 0.0 5.8e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EPE34874.1 - 2.1e-21 76.1 0.0 1.5e-18 66.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EPE34874.1 - 7.8e-09 35.7 0.0 7.8e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Opy2 PF09463.10 EPE34875.1 - 2.3e-07 31.0 23.2 3.6e-07 30.4 23.2 1.3 1 0 0 1 1 1 1 Opy2 protein Glt_symporter PF03616.14 EPE34875.1 - 0.042 12.6 0.0 0.057 12.1 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Mid2 PF04478.12 EPE34875.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Ras PF00071.22 EPE34876.1 - 8.1e-53 178.3 0.0 1.7e-52 177.3 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EPE34876.1 - 9.1e-18 64.6 0.0 1.5e-16 60.7 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE34876.1 - 0.00017 21.1 0.1 0.0006 19.3 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EPE34876.1 - 0.0081 16.1 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EPE34876.1 - 0.014 15.0 0.1 0.33 10.5 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B SRPRB PF09439.10 EPE34876.1 - 0.018 14.5 0.0 0.56 9.6 0.0 2.3 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EPE34876.1 - 0.14 12.5 0.2 0.26 11.7 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain Ferritin_2 PF13668.6 EPE34877.1 - 1.1e-12 48.3 0.0 1.9e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain PIR PF00399.19 EPE34877.1 - 2.5e-06 26.9 29.8 2.6e-06 26.8 5.9 3.3 2 1 1 3 3 3 2 Yeast PIR protein repeat Ferritin-like PF12902.7 EPE34877.1 - 0.034 14.0 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like DLH PF01738.18 EPE34878.1 - 2.1e-26 92.8 0.1 4.4e-26 91.8 0.1 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Hamartin PF04388.12 EPE34878.1 - 4.5e-20 71.9 44.0 1.8e-18 66.7 43.9 3.7 1 1 0 1 1 1 1 Hamartin protein GAIN_A PF18619.1 EPE34878.1 - 0.13 12.5 1.9 1.2 9.4 2.1 2.7 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Ribosomal_L23 PF00276.20 EPE34879.1 - 5.3e-11 42.7 0.0 1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 MT-A70 PF05063.14 EPE34880.1 - 6.1e-34 117.4 0.2 1.1e-33 116.6 0.2 1.4 1 0 0 1 1 1 1 MT-A70 G8 PF10162.9 EPE34880.1 - 0.081 13.0 0.0 0.59 10.2 0.0 2.0 2 0 0 2 2 2 0 G8 domain Methyltransf_15 PF09445.10 EPE34880.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Mito_carr PF00153.27 EPE34881.1 - 1.3e-61 204.5 0.7 5.2e-22 77.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein polyprenyl_synt PF00348.17 EPE34883.1 - 7.6e-50 169.3 0.0 6.9e-48 162.9 0.0 2.2 2 0 0 2 2 2 2 Polyprenyl synthetase Terpene_synth_C PF03936.16 EPE34883.1 - 0.021 14.2 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain Tim17 PF02466.19 EPE34885.1 - 7.4e-32 110.0 8.6 9.5e-32 109.7 8.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.6 EPE34885.1 - 0.19 11.9 0.0 0.37 11.0 0.0 1.6 1 1 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal adh_short_C2 PF13561.6 EPE34886.1 - 1.5e-55 188.3 0.1 2.4e-55 187.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE34886.1 - 3e-48 163.9 0.2 3.9e-48 163.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE34886.1 - 1.5e-13 51.1 0.4 2.2e-13 50.5 0.4 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EPE34886.1 - 0.023 14.6 0.1 0.034 14.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TRAP_beta PF05753.14 EPE34886.1 - 0.053 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) Epimerase PF01370.21 EPE34886.1 - 0.11 12.0 1.9 0.15 11.5 0.1 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family CCDC53 PF10152.9 EPE34887.1 - 0.02 15.3 1.0 0.024 15.1 1.0 1.0 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Zn_clus PF00172.18 EPE34888.1 - 0.00026 21.0 7.8 0.00058 19.9 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE34888.1 - 0.00029 19.9 0.4 0.00029 19.9 0.4 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE34889.1 - 2.8e-07 30.5 8.0 2.8e-07 30.5 8.0 2.2 2 1 1 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAT PF16073.5 EPE34890.1 - 4.6e-73 245.9 1.5 4.6e-73 245.9 1.5 2.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 EPE34890.1 - 3.3e-72 243.1 0.0 8.6e-72 241.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EPE34890.1 - 3.4e-41 141.8 0.0 1.1e-40 140.1 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE34890.1 - 2.7e-37 127.4 0.6 8.5e-37 125.8 0.6 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EPE34890.1 - 4.9e-20 72.6 0.0 5.8e-19 69.1 0.0 2.8 3 1 0 3 3 3 1 Thioesterase domain PP-binding PF00550.25 EPE34890.1 - 6.9e-20 71.2 4.0 4.7e-09 36.5 0.4 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 EPE34890.1 - 2.4e-15 56.6 0.0 3.7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 EPE34890.1 - 9.1e-05 21.9 0.1 0.00051 19.5 0.0 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 EPE34890.1 - 0.00018 22.2 3.1 0.15 12.6 0.0 3.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 EPE34890.1 - 0.001 19.5 0.0 0.0045 17.4 0.0 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Hydrolase_4 PF12146.8 EPE34890.1 - 0.039 13.2 0.0 0.15 11.3 0.0 2.0 3 0 0 3 3 3 0 Serine aminopeptidase, S33 RPA_C PF08784.11 EPE34890.1 - 0.17 12.6 0.1 27 5.5 0.0 2.8 2 0 0 2 2 2 0 Replication protein A C terminal Ank_2 PF12796.7 EPE34891.1 - 2.1e-36 124.4 9.3 1.2e-06 28.9 0.0 13.6 12 1 4 16 16 16 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE34891.1 - 6.5e-13 48.9 12.6 0.065 13.8 0.0 12.1 14 1 1 15 15 15 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE34891.1 - 1.9e-08 33.9 13.9 3.6 8.5 0.0 14.4 18 0 0 18 18 18 1 Ankyrin repeat Ank_5 PF13857.6 EPE34891.1 - 2.4e-05 24.5 15.2 0.2 12.0 0.0 10.1 13 2 1 15 15 15 2 Ankyrin repeats (many copies) Ank PF00023.30 EPE34891.1 - 0.0002 21.6 26.4 41 4.9 0.0 14.1 13 2 1 14 14 14 0 Ankyrin repeat Ion_trans PF00520.31 EPE34892.1 - 1.4e-07 31.0 26.1 2e-07 30.5 26.1 1.2 1 0 0 1 1 1 1 Ion transport protein FYDLN_acid PF09538.10 EPE34892.1 - 2.2 9.0 19.3 1.2 9.8 10.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Sds3 PF08598.11 EPE34893.1 - 7.1e-31 107.9 0.1 1.3e-30 107.0 0.1 1.4 1 1 0 1 1 1 1 Sds3-like DUF5327 PF17261.2 EPE34893.1 - 0.27 12.0 2.2 1.1 10.0 0.1 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5327) BRCT_2 PF16589.5 EPE34895.1 - 1.6e-07 31.6 0.0 3.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EPE34895.1 - 0.00012 22.0 0.3 0.00067 19.6 0.0 2.3 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 EPE34895.1 - 0.064 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain KilA-N PF04383.13 EPE34897.1 - 0.00036 20.3 0.0 0.0064 16.3 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain LapA_dom PF06305.11 EPE34898.1 - 0.12 12.2 2.6 0.22 11.3 2.6 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain FixS PF03597.15 EPE34898.1 - 0.48 10.2 3.0 0.98 9.2 3.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Aldedh PF00171.22 EPE34899.1 - 4.3e-09 35.4 8.9 0.00047 18.8 0.1 3.0 3 0 0 3 3 3 3 Aldehyde dehydrogenase family URO-D PF01208.17 EPE34899.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.4 1 1 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) PCI PF01399.27 EPE34900.1 - 0.0026 18.3 0.0 0.0052 17.3 0.0 1.5 1 0 0 1 1 1 1 PCI domain Rep_fac-A_C PF08646.10 EPE34901.1 - 4e-50 169.4 3.9 4e-50 169.4 3.9 2.7 2 1 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EPE34901.1 - 2.5e-38 129.9 3.3 4.3e-38 129.2 0.8 2.5 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 EPE34901.1 - 1.3e-24 86.2 0.4 3.6e-24 84.7 0.0 2.0 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EPE34901.1 - 5.6e-14 51.9 0.3 4.5e-10 39.4 0.0 3.8 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EPE34901.1 - 0.00068 19.4 0.2 0.015 15.0 0.1 2.7 2 1 0 2 2 2 1 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 EPE34901.1 - 0.0011 19.3 0.0 0.0085 16.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF223 zf-RRN7 PF11781.8 EPE34901.1 - 0.63 9.8 3.8 0.35 10.6 1.1 2.0 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 POT1 PF02765.17 EPE34901.1 - 3.4 7.5 8.2 0.27 11.1 0.1 3.2 5 0 0 5 5 5 0 Telomeric single stranded DNA binding POT1/CDC13 DLH PF01738.18 EPE34902.1 - 1.4e-20 73.8 0.1 2.6e-19 69.6 0.1 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EPE34902.1 - 0.0018 17.9 0.0 0.38 10.3 0.0 2.9 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EPE34902.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Amido_AtzD_TrzD PF09663.10 EPE34905.1 - 9.4e-115 383.5 1.2 1.1e-114 383.2 1.2 1.0 1 0 0 1 1 1 1 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Glyco_hydro_10 PF00331.20 EPE34906.1 - 1.8e-98 329.6 0.0 2.1e-98 329.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Tyrosinase PF00264.20 EPE34907.1 - 1.7e-32 113.5 3.7 2.5e-32 113.0 3.7 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase SCFA_trans PF02667.14 EPE34907.1 - 0.21 10.6 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 Short chain fatty acid transporter Sugar_tr PF00083.24 EPE34908.1 - 6.5e-129 430.7 28.7 8.1e-129 430.4 28.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE34908.1 - 3.5e-21 75.5 57.3 1.2e-19 70.5 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Arteri_Gl PF00951.18 EPE34908.1 - 0.026 14.3 1.2 0.026 14.3 1.2 1.8 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein Gram_pos_anchor PF00746.21 EPE34908.1 - 1.2 9.1 3.2 28 4.8 0.3 3.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Spike_NTD PF16451.5 EPE34909.1 - 0.053 12.9 0.3 0.087 12.2 0.3 1.3 1 0 0 1 1 1 0 Spike glycoprotein N-terminal domain Amastin PF07344.11 EPE34909.1 - 2.3 8.1 11.7 0.25 11.2 0.2 3.6 3 1 1 4 4 4 0 Amastin surface glycoprotein E1-E2_ATPase PF00122.20 EPE34910.1 - 4.6e-38 130.5 4.5 9.6e-37 126.3 0.3 3.5 3 1 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 EPE34910.1 - 4.3e-17 63.1 0.1 1e-16 61.9 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EPE34910.1 - 4.8e-10 39.0 0.0 1.2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EPE34910.1 - 0.0035 17.1 0.1 0.0059 16.4 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RINGv PF12906.7 EPE34911.1 - 0.018 15.2 11.1 0.045 13.9 11.1 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING_2 PF13639.6 EPE34911.1 - 0.041 14.2 11.0 0.076 13.4 11.0 1.5 1 0 0 1 1 1 0 Ring finger domain Prok-RING_1 PF14446.6 EPE34911.1 - 0.33 10.9 9.5 0.85 9.6 9.6 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Fungal_trans_2 PF11951.8 EPE34913.1 - 8.1e-09 34.8 0.0 1.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 EPE34914.1 - 5.4e-52 176.1 0.0 7e-52 175.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE34914.1 - 1.4e-35 123.0 0.0 1.7e-35 122.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE34914.1 - 2.9e-11 43.6 0.0 4.1e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE34914.1 - 0.0018 17.4 0.0 0.0032 16.6 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EPE34914.1 - 0.027 14.7 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Lin0512_fam PF09585.10 EPE34914.1 - 0.041 13.9 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) DUF1776 PF08643.10 EPE34914.1 - 0.23 10.8 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Sugar_tr PF00083.24 EPE34915.1 - 7.6e-94 315.1 28.5 9.7e-94 314.8 28.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE34915.1 - 1.1e-14 54.1 45.4 8.4e-11 41.4 33.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HORMA PF02301.18 EPE34916.1 - 2.9e-11 43.4 0.0 4.1e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 HORMA domain CBS PF00571.28 EPE34916.1 - 0.05 14.1 0.1 0.22 12.0 0.1 2.0 1 1 1 2 2 2 0 CBS domain IBN_N PF03810.19 EPE34917.1 - 1.1e-08 34.8 0.0 6.1e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EPE34917.1 - 0.00036 20.6 0.0 0.0014 18.7 0.0 2.1 2 0 0 2 2 2 1 Exportin 1-like protein Ndc1_Nup PF09531.10 EPE34917.1 - 0.03 13.0 0.4 0.05 12.3 0.1 1.4 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup HEAT PF02985.22 EPE34917.1 - 0.052 13.8 0.1 79 3.9 0.1 3.9 3 0 0 3 3 3 0 HEAT repeat Med15_fungi PF05397.12 EPE34917.1 - 0.18 12.1 0.4 3.6 7.9 0.2 2.5 2 0 0 2 2 2 0 Mediator complex subunit 15 FAD_binding_4 PF01565.23 EPE34918.1 - 3e-24 85.4 1.1 4.7e-24 84.7 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE34918.1 - 1.8e-09 37.5 0.3 4.2e-09 36.3 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like HET PF06985.11 EPE34919.1 - 5.3e-30 104.7 0.8 8.7e-30 104.0 0.8 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ras PF00071.22 EPE34921.1 - 1.3e-59 200.4 0.2 1.6e-59 200.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE34921.1 - 1.7e-20 73.5 0.0 2.5e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE34921.1 - 2.2e-08 33.8 0.0 2.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EPE34921.1 - 2.2e-06 27.3 0.1 1.2e-05 25.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EPE34921.1 - 0.00015 21.7 0.3 0.57 10.1 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EPE34921.1 - 0.0023 18.0 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EPE34921.1 - 0.0031 17.5 0.0 0.0066 16.4 0.0 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 EPE34921.1 - 0.0042 16.6 0.0 0.0065 16.0 0.0 1.3 1 1 0 1 1 1 1 Ferrous iron transport protein B MoCF_biosynth PF00994.24 EPE34922.1 - 1.4e-28 99.4 0.0 2.2e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 EPE34922.1 - 0.0089 16.2 0.0 0.083 13.1 0.0 2.2 2 0 0 2 2 2 1 Damage-inducible protein CinA KH domain DUF1829 PF08862.10 EPE34922.1 - 0.12 12.9 0.5 4.8 7.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF1829 CRAL_TRIO PF00650.20 EPE34923.1 - 5.3e-26 91.2 0.0 7.7e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EPE34923.1 - 1.3e-10 41.3 0.0 3.2e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Glyco_hydro_61 PF03443.14 EPE34924.1 - 1.8e-32 112.9 0.0 2.7e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PapG_N PF03627.13 EPE34924.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 PapG carbohydrate binding domain PI31_Prot_N PF11566.8 EPE34926.1 - 2.1e-60 203.2 0.0 2.7e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EPE34926.1 - 6.9e-17 62.4 19.4 6.9e-17 62.4 19.4 2.5 2 1 0 2 2 2 1 PI31 proteasome regulator Acetyltransf_7 PF13508.7 EPE34928.1 - 0.008 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPE34928.1 - 0.011 15.9 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPE34928.1 - 0.056 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE34928.1 - 0.087 13.1 0.0 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Dcc1 PF09724.9 EPE34929.1 - 3.6e-07 29.8 0.1 4.3e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 RhoGEF PF00621.20 EPE34930.1 - 3.3e-22 79.6 0.0 1.2e-21 77.7 0.0 1.9 2 0 0 2 2 2 1 RhoGEF domain Nod1 PF17114.5 EPE34930.1 - 4.8e-05 23.5 0.0 0.00022 21.4 0.0 2.2 2 0 0 2 2 2 1 Gef2-related medial cortical node protein Nod1 DUF3507 PF12015.8 EPE34930.1 - 0.0012 18.6 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DUF1319 PF07028.11 EPE34930.1 - 0.01 16.0 1.1 0.029 14.6 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) ATG16 PF08614.11 EPE34930.1 - 0.037 14.3 17.9 0.031 14.5 10.6 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) JAKMIP_CC3 PF16034.5 EPE34930.1 - 0.067 13.1 6.1 0.18 11.7 6.1 1.7 1 0 0 1 1 1 0 JAKMIP CC3 domain HALZ PF02183.18 EPE34930.1 - 0.97 9.7 5.9 3.3 8.0 1.3 3.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1664 PF07889.12 EPE34930.1 - 7.5 6.6 6.1 1.5 8.8 0.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 EPE34930.1 - 9.6 6.4 8.3 4.9 7.4 0.1 3.5 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 TLP1_add_C PF18313.1 EPE34931.1 - 2.7e-26 91.3 0.0 1.1e-25 89.4 0.0 1.9 2 0 0 2 2 2 1 Thiolase-like protein type 1 additional C-terminal domain Thiolase_C PF02803.18 EPE34931.1 - 0.1 12.2 0.1 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 Thiolase, C-terminal domain Thiolase_N PF00108.23 EPE34931.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Glyco_hydro_15 PF00723.21 EPE34932.1 - 7.2e-87 292.0 0.0 8.6e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EPE34932.1 - 1.3e-20 73.1 0.0 3e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain CENP-M PF11111.8 EPE34933.1 - 0.0065 15.7 0.4 0.012 14.8 0.4 1.4 1 0 0 1 1 1 1 Centromere protein M (CENP-M) Spt4 PF06093.13 EPE34934.1 - 0.0031 17.6 4.2 0.0064 16.6 4.2 1.5 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Zn_clus PF00172.18 EPE34934.1 - 0.0066 16.5 5.6 0.013 15.6 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1290 PF06947.12 EPE34934.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1290) MOSC PF03473.17 EPE34935.1 - 7.5e-31 106.9 0.0 1.4e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EPE34935.1 - 5.3e-16 58.6 0.0 8.5e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain p450 PF00067.22 EPE34936.1 - 2e-68 231.3 0.0 2.5e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4244 PF14029.6 EPE34936.1 - 0.1 12.0 0.1 0.47 9.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) Methyltransf_25 PF13649.6 EPE34937.1 - 3.8e-09 37.1 0.0 5.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE34937.1 - 9.7e-07 29.4 0.0 1.3e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE34937.1 - 6.7e-05 22.7 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE34937.1 - 0.0067 17.1 0.0 0.0091 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain His_Phos_1 PF00300.22 EPE34938.1 - 3.7e-10 39.8 0.0 8.1e-10 38.7 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CsbD PF05532.12 EPE34939.1 - 1.9e-05 24.5 9.1 0.0048 16.8 1.9 2.2 2 0 0 2 2 2 2 CsbD-like DUF3632 PF12311.8 EPE34941.1 - 2.7e-18 67.0 0.0 3.9e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) VCBS PF13517.6 EPE34944.1 - 1e-32 112.5 63.9 3.6e-13 49.9 4.5 9.2 6 2 4 10 10 10 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 EPE34944.1 - 5.6e-12 46.4 0.0 1.3e-11 45.2 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 EPE34944.1 - 3.2e-08 33.1 7.9 2.7 7.3 0.0 6.9 5 1 2 7 7 7 4 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL PF00657.22 EPE34944.1 - 0.0047 16.9 0.3 0.015 15.3 0.3 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EPE34944.1 - 0.013 15.7 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.23 EPE34944.1 - 0.014 15.5 1.9 0.014 15.5 1.9 7.4 8 0 0 8 8 8 0 FG-GAP repeat Mito_fiss_reg PF05308.11 EPE34944.1 - 3.5 7.6 3.7 5.6 7.0 3.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator SBDS PF01172.18 EPE34945.1 - 3.8e-20 71.8 0.5 4.5e-20 71.5 0.5 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Thioredoxin_6 PF13848.6 EPE34945.1 - 0.093 12.6 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Clr2_transil PF16761.5 EPE34946.1 - 4.6e-24 85.0 0.2 1e-23 83.9 0.2 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 EPE34946.1 - 4.3e-11 43.8 4.2 2.4e-10 41.4 0.2 3.1 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 SNF2_N PF00176.23 EPE34947.1 - 1e-60 205.3 0.1 7.1e-60 202.6 0.1 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE34947.1 - 4.9e-14 52.6 0.0 2.4e-13 50.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EPE34947.1 - 2.7e-05 23.5 0.0 0.00012 21.4 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 EPE34947.1 - 0.00033 20.5 25.1 0.0012 18.7 10.4 3.3 3 0 0 3 3 3 2 PHD-finger ResIII PF04851.15 EPE34947.1 - 0.0024 17.9 0.0 0.0089 16.0 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zf_RING PF16744.5 EPE34947.1 - 0.02 15.0 14.6 0.07 13.3 2.4 2.8 2 0 0 2 2 2 0 KIAA1045 RING finger zf_PR_Knuckle PF18445.1 EPE34947.1 - 0.067 13.0 7.5 1.4 8.8 0.1 3.6 3 0 0 3 3 3 0 PR zinc knuckle motif C1_1 PF00130.22 EPE34947.1 - 1.1 9.2 23.8 3.2 7.7 8.1 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 EPE34947.1 - 3.3 7.3 18.1 1.5 8.4 5.0 3.2 2 1 1 3 3 3 0 PHD/FYVE-zinc-finger like domain GDA1_CD39 PF01150.17 EPE34948.1 - 4.1e-104 348.6 0.0 6e-104 348.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PPV_E2_C PF00511.17 EPE34948.1 - 0.038 14.2 0.1 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 E2 (early) protein, C terminal MmlI PF09448.10 EPE34948.1 - 0.056 13.9 0.0 0.18 12.2 0.0 1.9 2 0 0 2 2 2 0 Methylmuconolactone methyl-isomerase Ank_2 PF12796.7 EPE34949.1 - 1.7e-10 41.3 0.0 5.3e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE34949.1 - 1.3e-07 32.0 0.4 4.1e-06 27.2 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EPE34949.1 - 2.8e-07 30.7 0.0 5.2e-05 23.5 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EPE34949.1 - 9e-05 22.6 0.1 0.14 12.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EPE34949.1 - 0.00053 20.2 0.1 0.01 16.2 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DYW_deaminase PF14432.6 EPE34949.1 - 0.0035 17.2 2.3 0.46 10.4 2.3 2.4 1 1 0 1 1 1 1 DYW family of nucleic acid deaminases Asp PF00026.23 EPE34950.1 - 4.6e-17 62.4 3.4 6.5e-17 61.9 3.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Mucin15 PF15672.5 EPE34950.1 - 0.0041 16.7 0.0 0.0041 16.7 0.0 2.2 2 0 0 2 2 2 1 Cell-membrane associated Mucin15 TMEM51 PF15345.6 EPE34950.1 - 0.009 15.9 0.0 0.009 15.9 0.0 1.9 2 0 0 2 2 1 1 Transmembrane protein 51 SKG6 PF08693.10 EPE34950.1 - 0.011 15.1 1.7 0.026 13.9 1.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TAXi_N PF14543.6 EPE34950.1 - 0.015 15.5 1.1 0.066 13.4 0.1 2.3 2 0 0 2 2 2 0 Xylanase inhibitor N-terminal Syndecan PF01034.20 EPE34950.1 - 0.045 13.7 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain VSP PF03302.13 EPE34950.1 - 0.062 12.1 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Rax2 PF12768.7 EPE34950.1 - 0.073 12.5 1.0 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Adeno_E3_CR2 PF02439.15 EPE34950.1 - 0.079 12.7 0.4 0.18 11.6 0.4 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 EPE34950.1 - 0.12 13.3 0.0 0.23 12.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glycophorin_A PF01102.18 EPE34950.1 - 0.15 12.3 0.0 0.15 12.3 0.0 2.7 3 0 0 3 3 3 0 Glycophorin A MtrF PF09472.10 EPE34950.1 - 0.61 9.5 1.9 1.3 8.4 1.9 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) F-box-like PF12937.7 EPE34952.1 - 2.3e-09 37.0 0.1 4.4e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE34952.1 - 4.5e-09 36.0 0.0 9e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EPE34952.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 F-box F-box_5 PF18511.1 EPE34952.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 F-box DUF775 PF05603.12 EPE34953.1 - 7e-64 215.0 0.0 7.9e-64 214.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF4743 PF15916.5 EPE34954.1 - 8.1e-12 45.2 0.0 1.3e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 EPE34954.1 - 6.7e-08 32.6 0.0 1.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.15 EPE34955.1 - 1.7e-43 148.2 0.0 1.9e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EPE34955.1 - 2.6e-06 27.5 0.2 0.0018 18.3 0.1 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G PAXNEB PF05625.11 EPE34956.1 - 2.9e-117 391.9 0.0 3.4e-117 391.7 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 EPE34957.1 - 2.3e-11 43.6 0.0 4.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain RNase_PH PF01138.21 EPE34962.1 - 2e-26 93.1 0.0 3.4e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Anp1 PF03452.14 EPE34963.1 - 2.3e-112 374.7 0.4 1.6e-111 372.0 0.0 2.0 2 0 0 2 2 2 1 Anp1 DUF334 PF03904.13 EPE34963.1 - 0.81 9.2 6.4 1.4 8.4 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Sec7 PF01369.20 EPE34964.1 - 9e-65 217.8 0.4 1.4e-64 217.1 0.4 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EPE34964.1 - 1.5e-17 64.0 0.2 4.8e-16 59.1 0.0 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Auxin_repressed PF05564.12 EPE34964.1 - 0.1 13.3 4.4 0.05 14.3 0.6 2.4 2 0 0 2 2 2 0 Dormancy/auxin associated protein DUF4360 PF14273.6 EPE34965.1 - 1.4e-26 93.4 0.0 1.7e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) RRM_1 PF00076.22 EPE34966.1 - 4e-26 90.6 1.1 1.4e-12 47.2 0.3 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPE34966.1 - 9.1e-05 22.1 0.0 0.0013 18.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPE34966.1 - 0.00051 19.9 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EPE34966.1 - 0.0083 16.2 0.1 0.2 11.7 0.1 2.3 2 0 0 2 2 2 1 Limkain b1 DUF4523 PF15023.6 EPE34966.1 - 0.058 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 EPE34966.1 - 0.13 12.3 0.0 3.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EPE34966.1 - 0.66 10.2 4.1 2.3 8.4 0.2 3.2 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter ATP-synt_D PF01813.17 EPE34967.1 - 1.5e-72 243.6 1.1 1.8e-72 243.3 1.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.6 EPE34967.1 - 0.016 15.2 6.2 0.036 14.1 2.8 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 HtrL_YibB PF09612.10 EPE34967.1 - 0.024 14.2 0.4 0.038 13.5 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) Mig-14 PF07395.11 EPE34967.1 - 0.19 11.1 2.4 0.46 9.8 0.2 2.0 2 0 0 2 2 2 0 Mig-14 CobA_CobO_BtuR PF02572.15 EPE34967.1 - 0.29 11.4 3.0 0.7 10.1 0.1 2.4 2 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF2098 PF09871.9 EPE34967.1 - 0.76 10.2 4.1 0.99 9.8 0.9 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Ribosomal_L6e PF01159.19 EPE34967.1 - 5.3 7.6 8.5 2.3 8.8 5.8 1.8 2 0 0 2 2 2 0 Ribosomal protein L6e TPR_14 PF13428.6 EPE34968.1 - 8.2e-15 54.2 14.1 1.2 10.1 0.1 10.2 10 1 1 11 11 10 4 Tetratricopeptide repeat Suf PF05843.14 EPE34968.1 - 1.8e-09 38.1 9.1 0.15 12.0 0.5 5.9 4 1 2 6 6 6 3 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 EPE34968.1 - 2.2e-07 30.9 13.7 0.15 12.0 0.1 7.2 6 1 0 6 6 6 3 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 EPE34968.1 - 2.7e-07 30.1 5.6 0.00021 20.6 0.6 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPE34968.1 - 2.1e-06 27.5 9.0 0.028 14.6 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat RPN7 PF10602.9 EPE34968.1 - 8.1e-05 22.4 0.7 0.00073 19.3 0.3 2.9 2 1 0 2 2 2 1 26S proteasome subunit RPN7 SNAP PF14938.6 EPE34968.1 - 0.00032 20.2 4.1 0.85 9.0 0.1 4.5 4 1 1 5 5 5 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EPE34968.1 - 0.00033 20.9 8.6 2.9 8.2 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 EPE34968.1 - 0.0021 18.5 3.7 11 6.6 0.1 5.4 5 1 1 6 6 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EPE34968.1 - 0.0061 16.6 17.2 6 7.2 0.1 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EPE34968.1 - 0.019 14.1 10.4 0.089 11.9 0.2 5.0 4 2 1 6 6 6 0 NRDE-2, necessary for RNA interference SHNi-TPR PF10516.9 EPE34968.1 - 0.039 13.4 0.0 10 5.7 0.0 2.8 2 0 0 2 2 2 0 SHNi-TPR MIT PF04212.18 EPE34968.1 - 0.049 13.7 0.7 0.71 10.0 0.1 3.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain RACo_linker PF17650.1 EPE34968.1 - 0.15 11.9 0.5 0.86 9.5 0.0 2.5 3 0 0 3 3 3 0 RACo linker region TPR_17 PF13431.6 EPE34968.1 - 3.8 8.1 6.3 16 6.1 0.0 5.1 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPE34968.1 - 7.6 7.4 10.2 8 7.3 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat Zn_clus PF00172.18 EPE34970.1 - 4.5e-08 33.1 9.2 4.5e-08 33.1 9.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM193_C PF15914.5 EPE34970.1 - 0.034 13.9 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 FAM193 family C-terminal Ribonuclease_3 PF00636.26 EPE34971.1 - 3.5e-40 136.8 0.0 2e-19 70.2 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 EPE34971.1 - 2.7e-22 78.7 0.1 1.3e-20 73.3 0.0 3.3 3 0 0 3 3 3 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 EPE34971.1 - 9.4e-21 74.3 0.0 7.6e-09 35.8 0.0 4.0 3 1 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.31 EPE34971.1 - 7e-16 58.6 0.1 2.1e-15 57.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE34971.1 - 2.1e-14 53.9 0.1 5.1e-14 52.6 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EPE34971.1 - 1.6e-12 47.6 0.0 3.6e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 EPE34971.1 - 0.00013 22.6 0.0 0.97 10.2 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif TetR_C_13 PF16925.5 EPE34971.1 - 0.018 15.0 0.0 5.5 7.0 0.0 2.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AAA_22 PF13401.6 EPE34971.1 - 0.13 12.5 0.1 1.2 9.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain TAP42 PF04177.12 EPE34972.1 - 1e-107 360.0 1.2 1.1e-107 359.9 1.2 1.0 1 0 0 1 1 1 1 TAP42-like family Focal_AT PF03623.13 EPE34973.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Focal adhesion targeting region SOG2 PF10428.9 EPE34974.1 - 1.4 8.0 7.3 1.6 7.8 7.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Fig1 PF12351.8 EPE34976.1 - 2.5e-15 56.9 2.2 4.2e-15 56.2 2.2 1.3 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EPE34976.1 - 0.0019 17.8 10.0 0.023 14.4 5.3 2.2 2 1 1 3 3 3 2 SUR7/PalI family SLAC1 PF03595.17 EPE34976.1 - 0.0073 15.6 0.6 0.0073 15.6 0.6 1.7 2 0 0 2 2 2 1 Voltage-dependent anion channel Cation_ATPase_C PF00689.21 EPE34976.1 - 2.1 8.0 5.6 0.55 9.9 2.4 1.7 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus ERAP1_C PF11838.8 EPE34977.1 - 4.2e-83 279.5 0.7 2.1e-82 277.2 0.2 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EPE34977.1 - 2.9e-82 275.5 1.2 4.6e-82 274.8 1.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EPE34977.1 - 2.8e-43 148.3 0.1 2.4e-42 145.2 0.1 2.5 3 0 0 3 3 3 1 Peptidase M1 N-terminal domain DUF45 PF01863.17 EPE34977.1 - 0.14 12.2 0.1 0.42 10.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function DUF45 CBFD_NFYB_HMF PF00808.23 EPE34978.1 - 3.9e-06 27.0 0.1 5e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 EPE34978.1 - 0.00073 19.7 0.1 0.00081 19.6 0.1 1.1 1 0 0 1 1 1 1 CENP-W protein DUF1980 PF09323.10 EPE34978.1 - 0.071 13.0 0.0 0.071 13.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Mod_r PF07200.13 EPE34979.1 - 0.16 12.1 10.6 0.27 11.3 10.6 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein SRR1 PF07985.12 EPE34980.1 - 2.7e-13 49.7 0.2 5e-13 48.9 0.2 1.5 1 0 0 1 1 1 1 SRR1 SUZ PF12752.7 EPE34980.1 - 0.59 10.9 0.1 0.59 10.9 0.1 3.1 2 1 0 2 2 2 0 SUZ domain Tom5 PF10642.9 EPE34980.1 - 2.5 8.2 7.7 44 4.2 0.5 4.1 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase eIF-5a PF01287.20 EPE34980.1 - 5.9 7.1 9.2 2.5 8.3 0.6 3.4 3 0 0 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold PIR PF00399.19 EPE34981.1 - 7.9e-35 117.7 79.3 2.6e-07 30.0 5.8 7.1 6 1 1 7 7 7 6 Yeast PIR protein repeat Glyco_hydro_17 PF00332.18 EPE34982.1 - 5.2e-10 39.4 2.3 6.8e-06 25.9 1.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 HK PF02110.15 EPE34983.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Pro-kuma_activ PF09286.11 EPE34985.1 - 8.3e-31 107.2 0.2 1.1e-29 103.6 0.0 2.2 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EPE34985.1 - 2.7e-05 23.6 3.1 4.3e-05 22.9 3.1 1.2 1 0 0 1 1 1 1 Subtilase family DUF5579 PF17742.1 EPE34986.1 - 0.037 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5579) Glyco_hydro_43 PF04616.14 EPE34989.1 - 8.7e-73 245.1 1.0 1.1e-72 244.8 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EPE34989.1 - 1.7e-22 80.2 0.0 2.4e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Abhydrolase_2 PF02230.16 EPE34989.1 - 0.2 11.5 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Gly_kinase PF02595.15 EPE34990.1 - 0.22 10.5 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Glycerate kinase family MFS_1 PF07690.16 EPE34994.1 - 5.9e-35 120.8 32.4 9.9e-35 120.1 32.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 EPE34995.1 - 3.3e-07 30.2 0.1 5.6e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE34995.1 - 2.2e-05 25.2 0.0 3.7e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE34995.1 - 0.00077 18.8 0.0 0.002 17.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EPE34995.1 - 0.013 15.0 0.1 0.11 11.9 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family FAD_binding_3 PF01494.19 EPE34996.1 - 6e-16 58.6 0.6 3.9e-13 49.4 0.6 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EPE34996.1 - 0.00014 22.1 0.0 0.00093 19.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 EPE34996.1 - 0.24 10.4 0.0 1.3 8.0 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase 2OG-FeII_Oxy_2 PF13532.6 EPE34997.1 - 8.9e-25 88.0 0.0 4.7e-24 85.7 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3716 PF12511.8 EPE34998.1 - 1.2e-15 57.2 6.4 1.9e-15 56.7 6.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Fungal_trans_2 PF11951.8 EPE34999.1 - 7.9e-07 28.2 0.4 1.3e-06 27.5 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE34999.1 - 0.00015 21.8 5.3 0.00043 20.3 5.3 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TetR_C_19 PF17924.1 EPE34999.1 - 0.042 14.4 0.0 0.096 13.3 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Alginate_lyase2 PF08787.11 EPE35001.1 - 3.6e-48 164.5 0.0 4.1e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Polysacc_lyase PF14099.6 EPE35001.1 - 0.022 14.6 0.3 0.21 11.4 0.3 2.0 1 1 0 1 1 1 0 Polysaccharide lyase Ank_2 PF12796.7 EPE35003.1 - 1.4e-33 115.3 2.1 4.3e-12 46.5 0.0 8.1 5 3 3 9 9 9 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE35003.1 - 9.3e-29 99.4 2.0 8.4e-07 29.4 0.0 9.1 7 2 3 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE35003.1 - 3.5e-21 73.0 6.3 0.069 13.7 0.0 12.2 14 0 0 14 14 14 5 Ankyrin repeat Ank PF00023.30 EPE35003.1 - 1.5e-19 69.5 4.2 0.00041 20.7 0.1 10.2 12 0 0 12 12 12 4 Ankyrin repeat Clr5 PF14420.6 EPE35003.1 - 1.7e-17 63.4 2.6 2.8e-17 62.7 1.6 2.0 2 0 0 2 2 2 1 Clr5 domain Ank_5 PF13857.6 EPE35003.1 - 1.4e-10 41.2 3.3 0.22 11.9 0.0 6.8 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Gly_transf_sug PF04488.15 EPE35004.1 - 2.7e-15 56.8 0.0 4.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Pkinase PF00069.25 EPE35005.1 - 5.2e-64 216.1 0.0 7.5e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE35005.1 - 1.4e-29 103.2 0.0 2.2e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE35005.1 - 0.00023 20.6 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPE35005.1 - 0.0023 17.9 0.0 0.015 15.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EPE35005.1 - 0.0067 15.4 0.0 0.0093 14.9 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EPE35005.1 - 0.022 13.6 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Phage_int_SAM_1 PF02899.17 EPE35005.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Baculo_PEP_C PF04513.12 EPE35006.1 - 0.48 10.5 6.9 14 5.7 1.6 3.7 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3037 PF11236.8 EPE35006.1 - 0.9 10.0 12.0 0.18 12.3 2.9 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3037) MAD PF05557.13 EPE35006.1 - 3.6 5.8 42.0 0.1 10.9 1.4 2.7 2 1 0 2 2 2 0 Mitotic checkpoint protein Tropomyosin PF00261.20 EPE35006.1 - 5.8 6.2 45.8 2 7.7 0.6 3.3 3 0 0 3 3 3 0 Tropomyosin JHD PF17811.1 EPE35006.1 - 8.2 7.0 9.4 0.38 11.3 0.4 2.9 1 1 2 3 3 3 0 Jumonji helical domain DUF4336 PF14234.6 EPE35007.1 - 3.8e-18 65.8 0.4 1.4e-14 54.1 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) Lactamase_B_5 PF14597.6 EPE35007.1 - 0.085 12.3 0.0 2.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily IMS PF00817.20 EPE35009.1 - 2.4e-33 115.2 0.0 4.9e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EPE35009.1 - 5e-12 46.5 0.0 1.1e-11 45.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 EPE35009.1 - 5e-11 42.0 2.0 6.2e-11 41.7 0.4 2.0 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 EPE35009.1 - 1.2e-05 25.4 0.0 3.8e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif DHHC PF01529.20 EPE35012.1 - 2.2e-30 105.5 1.8 2.2e-30 105.5 1.8 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase peroxidase PF00141.23 EPE35013.1 - 9.7e-16 58.2 0.0 2e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Peroxidase Exo_endo_phos PF03372.23 EPE35014.1 - 2.5e-07 30.5 0.0 4.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PI3Ka PF00613.20 EPE35015.1 - 1.2e-54 184.5 0.1 2.2e-54 183.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EPE35015.1 - 1.1e-45 156.4 0.0 3.5e-43 148.2 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EPE35015.1 - 7.6e-35 119.9 0.0 1.3e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 HpaP PF09483.10 EPE35015.1 - 0.12 12.7 0.5 4.4 7.6 0.1 3.1 2 1 1 3 3 3 0 Type III secretion protein (HpaP) Nse4_C PF08743.10 EPE35016.1 - 1.5e-34 118.1 0.0 4.6e-34 116.6 0.0 1.9 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EPE35016.1 - 9.4e-14 51.3 0.3 2e-13 50.2 0.3 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE FSH1 PF03959.13 EPE35017.1 - 1.2e-53 181.9 0.0 1.6e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 EPE35017.1 - 0.00055 19.5 0.0 0.00097 18.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EPE35017.1 - 0.001 18.4 0.3 0.12 11.6 0.0 2.6 2 1 1 3 3 3 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 EPE35017.1 - 0.0067 16.4 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 EPE35017.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 EPE35017.1 - 0.019 14.6 0.0 4.1 7.0 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EPE35017.1 - 0.064 12.8 0.0 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) HsbA PF12296.8 EPE35018.1 - 1.4e-20 73.9 0.7 2.2e-20 73.3 0.7 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Dimeth_Pyl PF09505.10 EPE35018.1 - 0.017 13.7 0.1 0.018 13.6 0.1 1.1 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) APH PF01636.23 EPE35019.1 - 1.4e-12 48.0 0.0 2.2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE35019.1 - 0.00028 20.5 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EPE35019.1 - 0.22 11.1 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family zf-HYPF PF07503.12 EPE35019.1 - 4.5 7.1 5.2 2.6 7.9 2.7 1.8 2 0 0 2 2 2 0 HypF finger RabGAP-TBC PF00566.18 EPE35021.1 - 9.3e-47 159.5 0.0 1.3e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 EPE35021.1 - 1.4e-05 24.6 0.4 0.014 15.2 0.3 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EPE35021.1 - 0.00043 19.6 1.0 0.075 12.6 0.6 3.2 3 0 0 3 3 3 1 EF hand GRAM PF02893.20 EPE35021.1 - 0.002 18.0 0.0 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.6 EPE35021.1 - 0.0028 18.1 1.1 0.047 14.2 0.4 3.1 2 1 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EPE35021.1 - 0.043 13.3 0.2 0.14 11.7 0.2 1.9 1 0 0 1 1 1 0 EF hand PTR2 PF00854.21 EPE35022.1 - 3.9e-63 213.6 1.3 7.2e-63 212.8 1.3 1.4 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 EPE35022.1 - 4.5e-05 22.5 24.8 0.00067 18.7 9.3 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sulfatase PF00884.23 EPE35025.1 - 3.8e-64 217.0 0.1 5.7e-64 216.4 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EPE35025.1 - 0.0001 22.1 0.1 0.00016 21.4 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 EPE35025.1 - 0.042 14.1 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) EMC1_C PF07774.13 EPE35026.1 - 5.3e-71 238.7 0.0 1.1e-70 237.7 0.0 1.5 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EPE35026.1 - 4.6e-23 82.0 9.4 5.6e-20 71.9 1.0 3.0 4 0 0 4 4 4 2 PQQ-like domain PQQ PF01011.21 EPE35026.1 - 1.4e-05 24.8 3.5 0.056 13.4 0.1 4.6 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_3 PF13570.6 EPE35026.1 - 0.28 11.7 3.1 11 6.7 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain adh_short_C2 PF13561.6 EPE35027.1 - 5.6e-32 111.2 0.0 7.5e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE35027.1 - 9.5e-29 100.3 0.0 1.1e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE35027.1 - 0.00018 21.5 0.3 0.00035 20.6 0.1 1.5 2 0 0 2 2 2 1 KR domain Acetate_kinase PF00871.17 EPE35027.1 - 0.023 13.4 0.0 0.031 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetokinase family Eno-Rase_NADH_b PF12242.8 EPE35027.1 - 0.032 14.0 0.1 0.055 13.2 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.19 EPE35027.1 - 0.044 13.1 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Helicase_RecD PF05127.14 EPE35027.1 - 0.048 13.5 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Helicase NAD_binding_7 PF13241.6 EPE35027.1 - 0.076 13.5 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding Glyco_tran_WecB PF03808.13 EPE35027.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family DUF1989 PF09347.10 EPE35028.1 - 3.7e-51 173.1 0.0 4.2e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF2981 PF11200.8 EPE35029.1 - 0.0083 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2981) RTC PF01137.21 EPE35030.1 - 3.4e-53 180.1 0.0 4.3e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Egh16-like PF11327.8 EPE35031.1 - 1.1e-54 185.6 14.5 1.4e-54 185.3 14.5 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor Glyoxalase PF00903.25 EPE35032.1 - 3.3e-07 30.5 0.0 5.3e-07 29.9 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EPE35032.1 - 0.0033 17.7 0.0 0.0046 17.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EPE35032.1 - 0.0066 16.6 0.0 0.029 14.5 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain ThiF PF00899.21 EPE35033.1 - 1.2e-40 139.5 0.0 1.9e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EPE35033.1 - 0.0021 18.3 0.1 0.013 15.8 0.1 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EPE35033.1 - 0.0028 17.9 0.7 0.0082 16.4 0.1 2.1 3 0 0 3 3 3 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EPE35033.1 - 0.01 15.4 0.1 0.032 13.8 0.1 1.7 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EPE35033.1 - 0.051 13.2 0.2 0.12 12.0 0.2 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF2252 PF10009.9 EPE35033.1 - 0.086 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Pyr_redox PF00070.27 EPE35033.1 - 0.34 11.5 1.3 5.1 7.7 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase OrsD PF12013.8 EPE35034.1 - 1.9e-21 76.6 0.7 4.2e-21 75.5 0.7 1.6 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D Fungal_trans_2 PF11951.8 EPE35034.1 - 6e-11 41.8 0.4 4e-10 39.1 0.7 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.25 EPE35035.1 - 6.3e-16 58.4 0.0 3.3e-13 49.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EPE35035.1 - 9.6e-08 32.1 0.0 1.3e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EPE35035.1 - 1.5e-05 24.7 0.0 2.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sulfotransfer_4 PF17784.1 EPE35035.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase domain HET PF06985.11 EPE35036.1 - 7.7e-34 117.1 4.6 8.2e-33 113.8 3.6 2.7 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CorA PF01544.18 EPE35037.1 - 0.068 12.5 0.1 0.17 11.2 0.1 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Ad_Cy_reg PF16701.5 EPE35037.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain Methyltransf_23 PF13489.6 EPE35040.1 - 2.1e-27 96.0 0.1 4.1e-27 95.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE35040.1 - 3.6e-14 53.2 0.0 9.6e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE35040.1 - 1.9e-13 50.9 0.0 4.7e-13 49.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE35040.1 - 8.9e-11 42.4 0.0 7.8e-10 39.4 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE35040.1 - 1.7e-10 40.9 0.0 7e-09 35.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE35040.1 - 8.6e-05 22.0 0.0 0.011 15.1 0.0 2.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EPE35040.1 - 0.00033 20.2 0.0 0.0013 18.3 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.20 EPE35040.1 - 0.00037 19.9 0.0 0.00084 18.7 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 EPE35040.1 - 0.00067 19.8 0.0 0.00098 19.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 EPE35040.1 - 0.0017 17.8 0.0 0.0072 15.8 0.0 2.0 2 1 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EPE35040.1 - 0.0058 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EPE35040.1 - 0.014 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Met_10 PF02475.16 EPE35040.1 - 0.046 13.5 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_2 PF00891.18 EPE35040.1 - 0.091 12.0 0.0 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase domain Med13_C PF06333.12 EPE35040.1 - 0.18 11.1 3.0 0.22 10.7 3.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Methyltransf_2 PF00891.18 EPE35041.1 - 9.1e-24 83.9 0.0 1.4e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain RelB_leu_zip PF16180.5 EPE35041.1 - 0.00055 19.9 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 RelB leucine zipper DUF2805 PF10985.8 EPE35041.1 - 0.013 15.9 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) Methyltransf_25 PF13649.6 EPE35041.1 - 0.14 12.9 0.0 0.49 11.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 EPE35041.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain AMP-binding PF00501.28 EPE35042.1 - 3.8e-87 292.6 0.0 4.8e-87 292.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE35042.1 - 2.1e-07 31.8 0.6 6.4e-07 30.3 0.2 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF4070 PF13282.6 EPE35042.1 - 0.22 11.6 0.0 2.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) Asp PF00026.23 EPE35043.1 - 5e-67 226.6 13.9 5.9e-67 226.3 13.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPE35043.1 - 1.6e-10 41.5 8.2 3.4e-05 24.1 1.5 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EPE35043.1 - 2.5e-06 28.0 4.0 0.0007 20.2 0.7 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 EPE35043.1 - 0.0063 16.3 0.0 0.026 14.3 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EPE35043.1 - 0.047 14.2 2.7 0.7 10.5 0.4 2.8 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease ATP-synt_C PF00137.21 EPE35044.1 - 1.3e-28 99.1 34.3 3.6e-16 59.2 13.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.22 EPE35045.1 - 1.1e-80 271.1 0.0 7.6e-80 268.4 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EPE35045.1 - 5.7e-46 156.0 0.0 1.1e-45 155.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EPE35045.1 - 2.7e-36 125.5 0.0 4.5e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EPE35045.1 - 1.7e-14 53.6 0.0 3.2e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 EPE35045.1 - 0.0047 16.7 0.0 0.041 13.7 0.0 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EPE35045.1 - 0.14 12.7 0.0 0.52 10.9 0.0 2.1 1 0 0 1 1 1 0 PH domain PGA2 PF07543.12 EPE35046.1 - 2.6 8.1 13.8 0.46 10.5 10.0 1.7 1 1 0 1 1 1 0 Protein trafficking PGA2 Amidase PF01425.21 EPE35047.1 - 2.3e-102 343.3 0.0 9.3e-102 341.3 0.0 1.8 1 1 0 1 1 1 1 Amidase Autophagy_N PF03986.13 EPE35048.1 - 1.2e-42 145.1 0.0 2.3e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 EPE35048.1 - 4.8e-16 57.9 1.0 9.2e-16 57.0 1.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 EPE35048.1 - 8.7e-15 55.1 0.2 1.4e-14 54.3 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain DUF2052 PF09747.9 EPE35049.1 - 5.2e-30 105.1 15.3 1.5e-28 100.3 15.3 2.0 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Herpes_UL56 PF04534.12 EPE35049.1 - 0.062 12.8 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein Y_phosphatase3 PF13350.6 EPE35050.1 - 3.7e-58 197.3 0.0 4.1e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EPE35050.1 - 7.5e-05 22.4 0.1 0.00013 21.7 0.1 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 EPE35050.1 - 0.0033 16.4 0.0 0.089 11.7 0.0 2.1 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase2 PF03162.13 EPE35050.1 - 0.0053 16.4 0.1 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family HTH_46 PF15977.5 EPE35050.1 - 0.12 12.3 0.0 0.38 10.8 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding Bot1p PF12298.8 EPE35051.1 - 1.6e-47 161.9 3.9 7.4e-47 159.7 3.9 2.0 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein CBFD_NFYB_HMF PF00808.23 EPE35052.1 - 6.5e-17 61.6 1.3 8.7e-17 61.2 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EPE35052.1 - 4.6e-06 27.0 0.0 1.3e-05 25.5 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Metallophos PF00149.28 EPE35053.1 - 7.4e-11 42.9 1.1 1.2e-10 42.2 0.4 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PRP38 PF03371.15 EPE35054.1 - 5.8e-57 192.3 0.0 6.8e-57 192.1 0.0 1.0 1 0 0 1 1 1 1 PRP38 family Cu-oxidase_2 PF07731.14 EPE35055.1 - 3.5e-31 107.7 1.5 3.6e-29 101.3 0.3 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EPE35055.1 - 1.2e-20 73.7 1.2 2.1e-15 56.8 0.1 3.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EPE35055.1 - 0.00015 21.9 0.3 0.52 10.4 0.0 3.5 2 2 0 2 2 2 2 Multicopper oxidase Fungal_trans_2 PF11951.8 EPE35056.1 - 5.9e-08 31.9 3.5 6.4e-08 31.8 1.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE35056.1 - 3.9e-06 26.9 12.8 6.2e-06 26.2 12.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2982 PF11201.8 EPE35057.1 - 0.091 12.3 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) Methyltransf_25 PF13649.6 EPE35058.1 - 2.2e-12 47.5 0.0 3.2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE35058.1 - 1.2e-11 45.2 0.0 1.7e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE35058.1 - 6.1e-11 42.8 0.0 9.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE35058.1 - 3.7e-10 39.9 0.0 4.7e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE35058.1 - 1.9e-09 37.5 0.0 2.3e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 EPE35058.1 - 0.0039 16.7 0.0 0.0052 16.3 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Ubie_methyltran PF01209.18 EPE35058.1 - 0.032 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EPE35058.1 - 0.091 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.18 EPE35058.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_33 PF10017.9 EPE35058.1 - 0.18 10.9 0.0 0.36 9.9 0.0 1.4 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent ADH_zinc_N PF00107.26 EPE35060.1 - 2.5e-15 56.6 0.0 4.1e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE35060.1 - 1.8e-05 25.8 0.0 3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE35060.1 - 0.026 14.4 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain AAR2 PF05282.11 EPE35060.1 - 0.049 13.0 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 AAR2 protein Transket_pyr PF02779.24 EPE35061.1 - 1.5e-46 158.3 0.0 2e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EPE35061.1 - 2.1e-35 121.3 0.2 6.1e-35 119.8 0.1 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain FtsA PF14450.6 EPE35061.1 - 0.1 13.0 0.0 0.32 11.4 0.0 1.8 2 0 0 2 2 2 0 Cell division protein FtsA Aminotran_5 PF00266.19 EPE35061.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V 2OG-FeII_Oxy_3 PF13640.6 EPE35062.1 - 1.1e-12 48.7 0.1 1.9e-12 47.9 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CTV_P6 PF06706.11 EPE35062.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein Thioredoxin_6 PF13848.6 EPE35063.1 - 2e-16 60.4 0.0 2.5e-12 47.1 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 EPE35063.1 - 2.8e-09 36.9 0.0 3.3e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin zf-C2H2_jaz PF12171.8 EPE35064.1 - 2.8e-07 30.6 2.4 5e-07 29.9 2.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPE35064.1 - 0.00064 20.0 0.5 0.0013 19.1 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 EPE35064.1 - 0.01 15.9 3.0 0.018 15.1 3.0 1.4 1 0 0 1 1 1 0 DBF zinc finger Connexin40_C PF16791.5 EPE35064.1 - 0.03 15.6 0.8 0.06 14.6 0.8 1.5 1 0 0 1 1 1 0 Connexin 40 C-terminal domain zf-C2H2 PF00096.26 EPE35064.1 - 0.12 12.9 0.4 0.22 12.1 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE35064.1 - 0.12 13.3 0.2 0.25 12.3 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3449 PF11931.8 EPE35064.1 - 0.31 10.8 2.2 0.62 9.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Vps54 PF07928.12 EPE35065.1 - 7.3e-50 168.9 0.0 1.7e-49 167.7 0.0 1.7 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 EPE35065.1 - 9.6e-08 31.6 0.8 2.3e-07 30.4 0.1 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Chorion_S16 PF05836.12 EPE35065.1 - 0.085 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Chorion protein S16 FliJ PF02050.16 EPE35065.1 - 0.12 12.6 0.1 1.2 9.3 0.1 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein SnoaL_4 PF13577.6 EPE35066.1 - 5.4e-16 58.9 0.0 6.3e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Zn_clus PF00172.18 EPE35067.1 - 0.0013 18.8 12.1 0.0022 18.1 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrpF PF04303.13 EPE35068.1 - 1e-66 225.5 0.0 1.3e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 PrpF protein HET PF06985.11 EPE35069.1 - 6.7e-27 94.6 0.0 1.2e-26 93.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_lectin_2 PF18647.1 EPE35070.1 - 2.6e-10 40.7 2.4 6.8e-10 39.3 0.9 2.4 2 0 0 2 2 2 1 Alpha-galactosyl-binding fungal lectin Lipase_GDSL_2 PF13472.6 EPE35070.1 - 3.1e-06 27.7 0.0 8.6e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TT_ORF2a PF08197.11 EPE35070.1 - 0.083 12.9 3.5 6.6 6.8 0.2 2.7 2 0 0 2 2 2 0 pORF2a truncated protein Gly_transf_sug PF04488.15 EPE35072.1 - 1.9e-07 31.6 0.0 5.5e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EPE35072.1 - 0.00061 19.2 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Ferric_reduct PF01794.19 EPE35073.1 - 1.6e-25 89.6 14.6 3.4e-25 88.6 14.6 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EPE35073.1 - 0.00026 21.0 0.0 0.0065 16.5 0.0 2.5 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 EPE35073.1 - 0.00087 19.4 3.1 0.047 13.8 0.1 2.5 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF4233 PF14017.6 EPE35073.1 - 0.001 19.4 8.0 0.0035 17.6 8.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4233) CFEM PF05730.11 EPE35073.1 - 0.0024 17.9 2.5 0.0043 17.1 2.5 1.3 1 0 0 1 1 1 1 CFEM domain DUF4131 PF13567.6 EPE35073.1 - 1 9.0 6.2 1.6 8.3 4.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2070 PF09843.9 EPE35073.1 - 1.2 7.3 6.7 1.4 7.1 5.8 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) HNF_C PF09354.10 EPE35073.1 - 5.4 8.1 8.1 31 5.7 0.1 2.9 2 1 1 3 3 3 0 HNF3 C-terminal domain Methyltransf_25 PF13649.6 EPE35076.1 - 2.9e-13 50.3 0.0 4.5e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE35076.1 - 1.6e-11 44.7 0.0 2.5e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE35076.1 - 9.8e-09 35.2 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE35076.1 - 1.1e-07 32.5 0.0 2.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE35076.1 - 1.5e-06 27.7 0.0 1.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EPE35076.1 - 9.1e-06 25.3 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EPE35076.1 - 2.3e-05 24.3 0.0 3.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EPE35076.1 - 0.00036 20.0 0.0 0.00048 19.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 EPE35076.1 - 0.0012 18.5 0.0 0.0016 18.1 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_PK PF05891.12 EPE35076.1 - 0.0072 15.9 0.0 0.01 15.4 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltrans_SAM PF10672.9 EPE35076.1 - 0.027 13.6 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase GMC_oxred_N PF00732.19 EPE35077.1 - 5.5e-58 196.7 0.0 8.1e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE35077.1 - 6.3e-32 111.1 0.0 9.7e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EPE35077.1 - 4.1e-06 26.1 0.6 6.2e-06 25.5 0.6 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EPE35077.1 - 0.0001 21.5 0.5 0.28 10.2 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EPE35077.1 - 0.0062 16.7 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE35077.1 - 0.035 13.3 0.0 0.086 12.1 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE35077.1 - 0.043 13.4 0.6 0.25 10.9 0.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EPE35077.1 - 0.047 12.5 0.2 0.069 12.0 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 EPE35077.1 - 0.094 11.9 1.3 0.13 11.5 0.1 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 EPE35077.1 - 0.12 12.9 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.25 EPE35078.1 - 4.9e-24 84.9 0.0 5.7e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE35078.1 - 9.4e-16 58.1 0.0 2.2e-14 53.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE35078.1 - 2.7e-05 24.1 0.0 4.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE35078.1 - 0.082 12.3 0.0 11 5.3 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Helo_like_N PF17111.5 EPE35079.1 - 1.9e-05 24.2 1.4 1.9e-05 24.2 1.4 2.3 2 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Aldose_epim PF01263.20 EPE35081.1 - 1.5e-35 123.0 0.1 1.8e-35 122.7 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase F-box-like PF12937.7 EPE35082.1 - 3.3e-12 46.1 0.3 1.1e-11 44.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EPE35082.1 - 1e-10 41.7 15.6 0.25 11.8 0.0 6.7 6 0 0 6 6 6 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EPE35082.1 - 8.7e-06 25.4 25.8 4.4 7.6 0.0 11.1 13 0 0 13 13 13 4 Leucine Rich repeat F-box PF00646.33 EPE35082.1 - 0.0084 16.0 0.1 0.029 14.3 0.1 2.1 1 0 0 1 1 1 1 F-box domain Preseq_ALAS PF09029.10 EPE35082.1 - 1.7 9.1 7.3 21 5.6 2.5 3.2 2 1 1 3 3 3 0 5-aminolevulinate synthase presequence Chalcone_2 PF16035.5 EPE35083.1 - 1.4e-78 263.3 0.0 1.8e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 EPE35083.1 - 0.0014 18.8 0.1 1.5 8.9 0.0 2.3 1 1 0 2 2 2 2 Chalcone isomerase-like BAALC_N PF06989.12 EPE35083.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 BAALC N-terminus Glutaredoxin PF00462.24 EPE35084.1 - 1.7e-18 66.6 0.0 2.5e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin PF00085.20 EPE35084.1 - 0.0023 17.9 0.0 0.0026 17.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EPE35084.1 - 0.0082 16.6 0.1 0.011 16.2 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.20 EPE35084.1 - 0.0094 15.7 0.0 0.02 14.6 0.0 1.5 1 1 1 2 2 2 1 DSBA-like thioredoxin domain DUF836 PF05768.14 EPE35084.1 - 0.013 15.9 0.1 0.021 15.2 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) TraF PF13728.6 EPE35084.1 - 0.044 13.6 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 EPE35084.1 - 0.097 12.7 0.0 0.13 12.3 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin domain BAG PF02179.16 EPE35085.1 - 8.6e-21 74.2 0.1 1.5e-20 73.4 0.1 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 EPE35085.1 - 9.1e-05 22.1 0.1 0.00018 21.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Cwf_Cwc_15 PF04889.12 EPE35085.1 - 2 8.1 7.0 4 7.1 2.6 2.6 2 1 1 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L13 PF00572.18 EPE35086.1 - 9.5e-11 42.0 0.0 8.3e-09 35.8 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 AMP-binding PF00501.28 EPE35087.1 - 2.9e-68 230.4 0.0 1.5e-67 228.1 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE35087.1 - 1.1e-19 71.2 0.1 2.2e-19 70.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Reticulon PF02453.17 EPE35088.1 - 0.022 14.7 0.7 0.024 14.6 0.7 1.1 1 0 0 1 1 1 0 Reticulon AA_permease_2 PF13520.6 EPE35089.1 - 2.3e-89 300.2 33.1 3e-89 299.8 33.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE35089.1 - 1.2e-16 60.5 31.4 1.6e-16 60.0 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease Phage_holin_2_2 PF10746.9 EPE35089.1 - 0.45 10.2 2.8 1.5 8.6 0.5 2.7 2 0 0 2 2 2 0 Phage holin T7 family, holin superfamily II SirB PF04247.12 EPE35089.1 - 4.6 7.3 7.9 0.31 11.1 0.2 3.0 3 0 0 3 3 3 0 Invasion gene expression up-regulator, SirB MAF_flag10 PF01973.18 EPE35090.1 - 0.016 14.9 0.1 0.028 14.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF115 Methyltransf_25 PF13649.6 EPE35091.1 - 9.6e-16 58.3 0.0 1.5e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE35091.1 - 8.8e-13 48.3 0.0 1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE35091.1 - 2e-12 47.6 0.0 3.2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE35091.1 - 5.3e-10 39.4 0.0 7.6e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE35091.1 - 2.8e-09 37.6 0.0 4.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE35091.1 - 1.1e-08 34.7 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EPE35091.1 - 0.00031 20.9 0.0 0.0004 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 EPE35091.1 - 0.0015 18.4 0.0 0.0075 16.0 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 EPE35091.1 - 0.0037 16.8 0.0 1.2 8.5 0.0 2.1 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain N6_Mtase PF02384.16 EPE35091.1 - 0.03 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase MTS PF05175.14 EPE35091.1 - 0.043 13.4 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain UPF0020 PF01170.18 EPE35091.1 - 0.11 12.2 0.0 0.43 10.2 0.0 1.9 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 gpW PF02831.15 EPE35091.1 - 0.15 12.0 0.1 0.65 9.9 0.0 2.1 3 0 0 3 3 3 0 gpW NAAA-beta PF15508.6 EPE35092.1 - 1.1e-16 60.8 0.2 2.6e-16 59.7 0.2 1.6 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase SDA1 PF05285.12 EPE35092.1 - 3.3 7.0 15.1 4.2 6.7 15.1 1.2 1 0 0 1 1 1 0 SDA1 Peptidase_M28 PF04389.17 EPE35093.1 - 1.3e-38 132.7 0.1 2.4e-38 131.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EPE35093.1 - 0.00024 20.9 0.2 0.00057 19.6 0.2 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Pkinase PF00069.25 EPE35094.1 - 4.8e-40 137.6 0.0 7.3e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE35094.1 - 3.5e-27 95.3 0.0 5.3e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE35094.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EPE35094.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3535 PF12054.8 EPE35095.1 - 8.5e-127 424.0 4.6 2.5e-125 419.2 0.0 3.9 5 0 0 5 5 5 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EPE35095.1 - 1.2e-61 208.4 0.0 2.9e-61 207.1 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE35095.1 - 8.8e-19 67.9 0.0 2.3e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EPE35095.1 - 5.2e-14 51.1 15.4 0.013 15.6 0.0 9.3 10 0 0 10 10 8 4 HEAT repeat Vac14_Fab1_bd PF12755.7 EPE35095.1 - 2.2e-08 34.6 0.3 0.12 13.0 0.0 3.9 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EPE35095.1 - 2e-07 31.3 4.1 0.012 15.9 0.0 6.7 6 0 0 6 6 6 1 HEAT repeats CLASP_N PF12348.8 EPE35095.1 - 0.00037 20.1 0.4 0.92 9.0 0.1 3.7 2 2 1 3 3 3 2 CLASP N terminal TAF6_C PF07571.13 EPE35095.1 - 0.0021 18.3 0.0 1.6 9.1 0.0 5.0 4 1 1 5 5 5 1 TAF6 C-terminal HEAT repeat domain DUF3385 PF11865.8 EPE35095.1 - 0.035 14.0 0.0 0.35 10.8 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) ERCC3_RAD25_C PF16203.5 EPE35095.1 - 0.06 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase HTH_16 PF12645.7 EPE35095.1 - 0.12 12.4 0.1 0.64 10.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HEAT_EZ PF13513.6 EPE35095.1 - 0.56 10.8 18.0 9.1 6.9 0.0 7.6 8 1 0 8 8 7 0 HEAT-like repeat Adaptin_N PF01602.20 EPE35095.1 - 2.1 6.8 4.6 27 3.1 0.0 3.8 3 2 1 4 4 4 0 Adaptin N terminal region HEAT_PBS PF03130.16 EPE35095.1 - 2.3 9.1 6.0 32 5.6 0.0 5.6 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat Siah-Interact_N PF09032.11 EPE35096.1 - 5.3 7.4 8.7 0.51 10.7 2.2 2.9 2 0 0 2 2 2 0 Siah interacting protein, N terminal HlyIII PF03006.20 EPE35098.1 - 4.5e-45 154.1 15.2 4.5e-45 154.1 15.2 3.0 3 0 0 3 3 3 1 Haemolysin-III related MFS_1 PF07690.16 EPE35098.1 - 3.5e-16 59.1 12.8 3.5e-16 59.1 12.8 3.3 2 1 1 3 3 3 1 Major Facilitator Superfamily PUCC PF03209.15 EPE35098.1 - 0.00027 20.1 12.9 0.0012 18.0 12.9 1.9 1 1 0 1 1 1 1 PUCC protein GST_N PF02798.20 EPE35099.1 - 5.7e-13 49.0 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPE35099.1 - 2.5e-12 47.0 0.0 4.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EPE35099.1 - 8.9e-12 45.1 0.0 1.8e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EPE35099.1 - 5.6e-11 42.6 0.0 1.4e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EPE35099.1 - 7.3e-11 42.2 0.0 2e-10 40.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPE35099.1 - 4.2e-06 26.7 0.0 8.3e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SF1-HH PF16275.5 EPE35100.1 - 4.2e-44 149.5 0.7 8.7e-44 148.5 0.7 1.5 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 EPE35100.1 - 2.8e-12 46.1 11.1 9.1e-06 25.5 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EPE35100.1 - 9.6e-08 31.7 0.1 1.9e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 EPE35100.1 - 1.1e-05 25.3 10.3 0.00095 19.1 2.9 2.7 2 1 1 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.6 EPE35100.1 - 0.00072 19.2 5.0 0.3 10.9 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 EPE35100.1 - 0.0056 16.5 10.1 0.25 11.2 0.9 2.8 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 EPE35100.1 - 0.0099 15.7 0.5 0.0099 15.7 0.5 2.4 2 0 0 2 2 2 1 Zinc knuckle C1_2 PF03107.16 EPE35100.1 - 1.5 9.2 3.6 1.5 9.2 1.7 1.9 1 1 1 2 2 2 0 C1 domain Prim_Zn_Ribbon PF08273.12 EPE35100.1 - 4.7 7.6 8.0 0.49 10.7 3.0 2.0 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase E2R135 PF11570.8 EPE35101.1 - 0.0022 18.3 0.1 0.0022 18.3 0.1 3.8 5 1 0 5 5 5 1 Coiled-coil receptor-binding R-domain of colicin E2 DUF2203 PF09969.9 EPE35101.1 - 0.0072 17.0 0.8 0.0072 17.0 0.8 6.6 3 2 4 7 7 7 1 Uncharacterized conserved protein (DUF2203) DUF2779 PF11074.8 EPE35101.1 - 0.022 15.2 1.2 0.13 12.8 1.2 2.4 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) TMF_DNA_bd PF12329.8 EPE35101.1 - 0.034 14.1 55.1 0.87 9.6 2.6 8.0 4 2 3 7 7 7 0 TATA element modulatory factor 1 DNA binding PspB PF06667.12 EPE35101.1 - 0.098 12.7 0.1 0.098 12.7 0.1 3.7 3 0 0 3 3 3 0 Phage shock protein B Lebercilin PF15619.6 EPE35101.1 - 0.52 10.0 52.7 0.033 13.9 7.4 7.1 5 1 2 7 7 7 0 Ciliary protein causing Leber congenital amaurosis disease SlyX PF04102.12 EPE35101.1 - 2.4 8.8 55.3 0.76 10.4 2.0 8.9 7 3 3 10 10 10 0 SlyX DUF1192 PF06698.11 EPE35101.1 - 2.6 8.2 19.6 2.4 8.3 0.2 6.5 5 1 1 6 6 6 0 Protein of unknown function (DUF1192) DIT1_PvcA PF05141.12 EPE35101.1 - 4.3 6.7 10.9 0.44 10.0 3.2 2.6 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein FAD_binding_4 PF01565.23 EPE35102.1 - 1.4e-19 70.2 0.5 2.2e-19 69.6 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_3 PF00933.21 EPE35103.1 - 1.4e-55 188.9 0.0 1.9e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EPE35103.1 - 1.3e-50 172.2 1.9 2.3e-50 171.4 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EPE35103.1 - 3.3e-22 78.4 0.1 7.9e-22 77.2 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF829 PF05705.14 EPE35104.1 - 4.1e-53 180.7 0.0 4.8e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) HTH_AraC PF00165.23 EPE35105.1 - 0.18 11.9 1.2 0.37 10.9 1.2 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Sec39 PF08314.11 EPE35106.1 - 3.6e-269 895.3 0.0 4.2e-269 895.1 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.9 EPE35107.1 - 0.0002 21.6 0.0 0.00025 21.2 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 EPE35107.1 - 0.022 15.1 0.7 0.049 14.0 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) COX17 PF05051.13 EPE35107.1 - 0.04 14.3 0.5 0.066 13.6 0.5 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Nup54_57_C PF18570.1 EPE35107.1 - 0.18 11.5 0.8 0.28 10.8 0.8 1.3 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain RRM_1 PF00076.22 EPE35109.1 - 5.5e-19 67.8 0.0 8e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPE35109.1 - 2.7e-05 23.8 0.0 3.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1793 PF08760.11 EPE35110.1 - 2.9e-71 239.3 0.1 5e-71 238.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 EPE35110.1 - 7e-66 221.2 0.3 1.1e-50 171.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EPE35110.1 - 1.8e-43 148.9 0.5 3.5e-43 148.0 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 EPE35110.1 - 0.001 18.6 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) adh_short_C2 PF13561.6 EPE35111.1 - 4.6e-58 196.5 0.6 5.7e-29 101.3 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE35111.1 - 4.7e-47 160.0 0.5 5e-32 111.0 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EPE35111.1 - 1.9e-11 44.2 0.1 3.4e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE35111.1 - 0.023 14.2 0.0 0.039 13.4 0.0 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family SLATT_fungal PF18142.1 EPE35112.1 - 9e-29 99.9 0.3 1.2e-28 99.5 0.3 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain ATP_transf PF09830.9 EPE35113.1 - 5.5e-19 68.1 0.0 1.1e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase CwfJ_C_1 PF04677.15 EPE35113.1 - 0.019 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Myb_DNA-binding PF00249.31 EPE35114.1 - 0.0023 18.1 0.3 0.0079 16.4 0.3 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPE35114.1 - 0.0062 16.8 0.1 0.021 15.1 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EPE35114.1 - 0.016 15.5 0.3 0.052 13.9 0.3 1.9 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Xpo1 PF08389.12 EPE35115.1 - 3e-37 128.0 2.9 1.3e-36 125.9 0.3 3.0 2 1 1 3 3 3 1 Exportin 1-like protein SHR3_chaperone PF08229.11 EPE35115.1 - 0.011 14.7 0.5 1.2 8.1 0.0 2.6 3 0 0 3 3 3 0 ER membrane protein SH3 Mce4_CUP1 PF11887.8 EPE35115.1 - 0.085 12.3 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative HEAT PF02985.22 EPE35115.1 - 0.12 12.7 0.1 40 4.8 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat Iso_dh PF00180.20 EPE35116.1 - 7e-123 410.2 0.0 8.2e-123 410.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PHD PF00628.29 EPE35117.1 - 8.2e-10 38.4 5.3 1.4e-09 37.7 5.3 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 EPE35117.1 - 0.051 14.0 0.2 0.2 12.0 0.2 2.1 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx DUF4451 PF14616.6 EPE35118.1 - 3.4e-24 85.4 0.1 6.1e-24 84.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DUF2382 PF09557.10 EPE35121.1 - 3.5 7.9 6.6 3.2 8.0 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF2382) PHD20L1_u1 PF16660.5 EPE35122.1 - 0.048 14.4 2.3 0.077 13.7 0.1 2.1 2 0 0 2 2 2 0 PHD finger protein 20-like protein 1 MFS_1 PF07690.16 EPE35123.1 - 4.3e-21 75.2 32.2 5.3e-11 42.0 6.9 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.8 EPE35123.1 - 4.4e-05 22.3 0.2 0.0018 17.0 0.0 2.7 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 EPE35123.1 - 0.00011 21.3 3.9 0.11 11.3 0.0 3.0 4 0 0 4 4 4 2 MFS_1 like family DUF2206 PF09971.9 EPE35123.1 - 0.062 12.0 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) LacY_symp PF01306.19 EPE35123.1 - 1.3 7.7 12.5 0.039 12.7 1.2 3.1 4 0 0 4 4 4 0 LacY proton/sugar symporter HsbA PF12296.8 EPE35125.1 - 1.5 9.3 9.5 0.39 11.1 4.4 2.3 2 1 0 2 2 2 0 Hydrophobic surface binding protein A DUF1700 PF08006.11 EPE35125.1 - 2.9 7.4 8.6 4.5 6.8 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Metallophos PF00149.28 EPE35126.1 - 2.2e-12 47.9 1.2 4e-12 47.1 1.2 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPE35126.1 - 1.5e-05 25.2 0.0 6.8e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.16 EPE35127.1 - 8.4e-34 117.0 25.9 2.2e-33 115.6 26.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.18 EPE35128.1 - 6.7e-09 35.2 0.2 1.4e-08 34.1 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE35128.1 - 0.00032 20.8 16.9 0.00057 20.0 16.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IL5 PF02025.15 EPE35128.1 - 0.083 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Interleukin 5 Abhydrolase_3 PF07859.13 EPE35129.1 - 8.2e-07 29.1 0.1 1.4e-05 25.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE35129.1 - 0.00032 21.4 0.0 0.00067 20.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE35129.1 - 0.0018 18.0 0.0 0.3 10.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2974 PF11187.8 EPE35129.1 - 0.0067 16.0 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.21 EPE35129.1 - 0.012 15.1 0.0 0.23 10.9 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EPE35129.1 - 0.033 13.5 0.0 0.07 12.4 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 EPE35129.1 - 0.039 12.8 0.0 0.18 10.6 0.0 1.8 2 0 0 2 2 2 0 Steryl acetyl hydrolase LIDHydrolase PF10230.9 EPE35129.1 - 0.049 13.2 0.0 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF3530 PF12048.8 EPE35129.1 - 0.12 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF3089 PF11288.8 EPE35129.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Cupin_2 PF07883.11 EPE35130.1 - 0.00012 21.8 0.0 0.0004 20.1 0.0 1.8 1 1 0 1 1 1 1 Cupin domain FAD_binding_3 PF01494.19 EPE35131.1 - 2.7e-20 72.9 1.0 1.8e-14 53.8 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 EPE35131.1 - 0.00047 19.3 0.0 0.0011 18.0 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 EPE35131.1 - 0.0076 15.5 0.3 0.047 12.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE35131.1 - 0.0095 16.2 1.3 0.027 14.7 0.9 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPE35131.1 - 0.1 11.6 1.2 0.18 10.9 1.2 1.4 1 0 0 1 1 1 0 FAD binding domain PocR PF10114.9 EPE35131.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR DAO PF01266.24 EPE35131.1 - 0.3 10.6 3.2 1 8.9 2.9 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EPE35132.1 - 1.6e-15 57.3 0.1 5.4e-15 55.5 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPE35132.1 - 7.4e-07 29.1 6.6 2.5e-06 27.3 5.0 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE35132.1 - 1e-06 28.9 0.5 2.3e-06 27.7 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPE35132.1 - 8.7e-05 21.7 0.1 0.00013 21.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EPE35132.1 - 0.00017 20.9 0.1 0.00022 20.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE35132.1 - 0.0045 17.5 0.9 0.013 16.1 0.9 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EPE35132.1 - 0.011 15.1 0.2 0.019 14.3 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPE35132.1 - 0.012 14.8 3.1 0.025 13.7 2.7 1.7 1 1 1 2 2 2 0 FAD binding domain GIDA PF01134.22 EPE35132.1 - 0.058 12.5 1.8 0.096 11.7 0.7 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Glyco_tranf_2_4 PF13704.6 EPE35133.1 - 5.9e-07 29.9 0.6 2.1e-06 28.2 0.1 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 EPE35133.1 - 0.00014 21.6 1.8 0.00034 20.3 1.8 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 92 Fringe PF02434.16 EPE35133.1 - 0.093 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Fringe-like Asp PF00026.23 EPE35135.1 - 6e-55 186.9 0.2 7.1e-55 186.6 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPE35135.1 - 6.2e-07 29.8 0.6 0.00069 19.9 0.0 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EPE35135.1 - 0.00015 21.5 0.0 0.00037 20.3 0.0 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EPE35135.1 - 0.062 13.9 0.0 16 6.2 0.0 2.7 2 0 0 2 2 2 0 Aspartyl protease AlaDh_PNT_N PF05222.15 EPE35136.1 - 1e-29 103.6 0.0 1.6e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EPE35136.1 - 0.00067 19.0 0.0 0.0026 17.1 0.0 1.8 1 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EPE35137.1 - 3.8e-31 108.1 0.0 5.1e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE35137.1 - 3.5e-29 102.0 0.0 4.4e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Phage_AlpA PF05930.12 EPE35137.1 - 0.076 12.8 0.1 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Prophage CP4-57 regulatory protein (AlpA) Thg1 PF04446.12 EPE35138.1 - 6.1e-54 181.4 0.0 9.5e-54 180.7 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EPE35138.1 - 8.5e-52 174.4 1.9 1.2e-51 174.0 1.9 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain PA26 PF04636.13 EPE35139.1 - 3.2 6.6 10.3 4.4 6.1 10.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RFXA_RFXANK_bdg PF15289.6 EPE35140.1 - 0.11 12.9 0.2 0.84 10.0 0.1 2.3 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain AAA_23 PF13476.6 EPE35141.1 - 1.8e-32 113.4 0.3 1.8e-32 113.4 0.3 8.0 2 1 1 3 3 2 1 AAA domain AAA_15 PF13175.6 EPE35141.1 - 2.3e-12 47.3 0.0 2.3e-12 47.3 0.0 4.8 1 1 0 3 3 2 2 AAA ATPase domain AAA_21 PF13304.6 EPE35141.1 - 4e-12 46.6 0.1 9.1e-05 22.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EPE35141.1 - 1.1e-05 25.5 0.0 3.7e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 EPE35141.1 - 0.0003 20.3 51.5 0.0043 16.5 51.5 3.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EPE35141.1 - 0.00042 20.0 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 EPE35141.1 - 0.005 15.5 0.0 0.005 15.5 0.0 7.0 3 1 3 7 7 7 3 AAA domain AAA_22 PF13401.6 EPE35141.1 - 0.0087 16.3 4.9 0.016 15.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain DUF3800 PF12686.7 EPE35141.1 - 0.016 15.8 0.0 8 7.1 0.0 5.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) ABC_tran PF00005.27 EPE35141.1 - 0.052 14.1 0.0 0.052 14.1 0.0 6.9 3 2 0 4 4 2 0 ABC transporter AAA_16 PF13191.6 EPE35141.1 - 0.086 13.2 0.0 0.086 13.2 0.0 4.5 5 2 0 5 5 3 0 AAA ATPase domain DASH_Hsk3 PF08227.11 EPE35141.1 - 7 7.1 10.6 44 4.6 0.1 5.4 4 0 0 4 4 4 0 DASH complex subunit Hsk3 like Thioredoxin PF00085.20 EPE35142.1 - 8.5e-26 90.0 0.0 1.2e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EPE35142.1 - 1.7e-07 30.9 0.0 2.9e-07 30.1 0.0 1.3 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EPE35142.1 - 4.5e-06 26.9 0.0 0.00011 22.5 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EPE35142.1 - 4.8e-06 27.0 0.1 1.7e-05 25.2 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EPE35142.1 - 0.0032 17.2 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EPE35142.1 - 0.0033 17.1 0.1 2.7 7.7 0.1 2.2 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.21 EPE35142.1 - 0.0034 17.3 0.1 0.38 10.7 0.1 2.2 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EPE35142.1 - 0.018 15.2 0.0 0.028 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 EPE35142.1 - 0.022 14.7 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE SelK_SelG PF10961.8 EPE35142.1 - 0.089 13.4 0.0 0.2 12.3 0.0 1.6 1 1 0 1 1 1 0 Selenoprotein SelK_SelG TraF PF13728.6 EPE35142.1 - 0.1 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein WSC PF01822.19 EPE35144.1 - 8e-08 32.4 10.2 8e-08 32.4 10.2 2.0 2 0 0 2 2 2 1 WSC domain Adeno_E3_CR2 PF02439.15 EPE35144.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EPE35144.1 - 0.056 13.5 14.7 0.1 12.7 14.7 1.4 1 0 0 1 1 1 0 Podoplanin Med13_C PF06333.12 EPE35144.1 - 0.085 12.1 13.7 0.13 11.5 13.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain MLANA PF14991.6 EPE35144.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A DUF4381 PF14316.6 EPE35144.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PRCC PF10253.9 EPE35144.1 - 0.36 11.6 4.9 0.82 10.4 4.9 1.7 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SOG2 PF10428.9 EPE35144.1 - 0.74 8.9 16.1 1.1 8.4 16.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Gram_pos_anchor PF00746.21 EPE35144.1 - 2.3 8.3 5.7 1.3 9.0 0.5 2.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif NB-ARC PF00931.22 EPE35145.1 - 1.4e-06 27.7 0.0 2.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain DUF676 PF05057.14 EPE35145.1 - 7.8e-06 25.6 0.0 2.7e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EPE35145.1 - 9.5e-06 25.5 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.6 EPE35145.1 - 1.5e-05 25.3 0.0 0.0015 18.8 0.0 2.8 1 1 2 3 3 3 1 AAA domain AAA_14 PF13173.6 EPE35145.1 - 0.001 19.1 0.0 0.04 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPE35145.1 - 0.0023 18.4 1.0 0.058 13.8 0.1 3.1 3 1 0 3 3 3 1 AAA ATPase domain Abhydrolase_6 PF12697.7 EPE35145.1 - 0.013 16.1 1.1 0.013 16.1 1.1 1.8 3 0 0 3 3 3 0 Alpha/beta hydrolase family LCAT PF02450.15 EPE35145.1 - 0.041 13.0 0.1 0.066 12.4 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase NACHT PF05729.12 EPE35145.1 - 0.094 12.6 0.1 0.35 10.8 0.1 2.0 1 1 0 1 1 1 0 NACHT domain Abhydrolase_2 PF02230.16 EPE35145.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase CbiA PF01656.23 EPE35145.1 - 0.14 12.2 0.0 0.37 10.9 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2710 PF10921.8 EPE35145.1 - 0.17 12.3 0.2 0.9 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2710) TniB PF05621.11 EPE35145.1 - 0.18 11.2 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Sugar_tr PF00083.24 EPE35148.1 - 1.2e-52 179.3 17.8 1.6e-52 178.9 17.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE35148.1 - 4.8e-20 71.8 28.6 4.8e-20 71.8 28.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4576 PF15144.6 EPE35151.1 - 0.093 12.6 0.0 0.17 11.8 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4576) Oxidored-like PF09791.9 EPE35151.1 - 0.19 11.4 1.0 0.39 10.4 1.0 1.5 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal MFS_1 PF07690.16 EPE35153.1 - 2.3e-24 86.0 32.4 1.7e-16 60.2 18.8 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Ferrochelatase PF00762.19 EPE35155.1 - 1.2e-97 326.8 0.0 1.5e-97 326.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase ACC_epsilon PF13822.6 EPE35155.1 - 0.17 12.6 1.0 0.51 11.1 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit Ku PF02735.16 EPE35156.1 - 2.9e-46 157.8 0.0 9.7e-46 156.0 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EPE35156.1 - 4.1e-35 121.5 0.0 5.9e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EPE35156.1 - 9.5e-27 93.5 0.3 2.6e-26 92.1 0.3 1.8 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 EPE35156.1 - 1.5e-10 40.6 0.0 2.7e-08 33.4 0.1 2.8 1 1 1 2 2 2 2 SAP domain Ish1 PF10281.9 EPE35156.1 - 0.14 12.5 1.2 0.83 10.0 0.1 2.7 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Complex1_51K PF01512.17 EPE35156.1 - 0.15 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Solute_trans_a PF03619.16 EPE35157.1 - 1.2e-90 303.6 26.1 1.5e-90 303.4 26.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Fungal_trans_2 PF11951.8 EPE35159.1 - 1.8e-07 30.3 0.2 3e-07 29.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Transp_cyt_pur PF02133.15 EPE35160.1 - 1.5e-94 317.2 35.2 1.9e-94 317.0 35.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidase PF01425.21 EPE35162.1 - 5.9e-74 249.7 0.0 7.9e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.20 EPE35162.1 - 5.3e-38 130.9 0.0 9.2e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Fungal_trans PF04082.18 EPE35163.1 - 3.7e-21 75.3 0.0 6.1e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE35163.1 - 5.5e-06 26.4 9.3 8.9e-06 25.7 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTB PF00651.31 EPE35164.1 - 0.028 14.6 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain zf-CCCH PF00642.24 EPE35165.1 - 2.6 8.1 10.2 0.62 10.0 3.9 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Atg29_N PF18388.1 EPE35166.1 - 1.5e-28 98.3 1.1 3.2e-28 97.3 1.1 1.6 1 0 0 1 1 1 1 Atg29 N-terminal domain Patatin PF01734.22 EPE35167.1 - 3.5e-24 86.1 0.1 2.1e-22 80.3 0.0 2.6 2 1 0 2 2 2 1 Patatin-like phospholipase Ank_2 PF12796.7 EPE35167.1 - 0.00013 22.5 0.0 0.00068 20.2 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE35167.1 - 0.00015 22.2 0.1 0.06 13.9 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EPE35167.1 - 0.00056 20.2 1.7 0.13 12.8 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EPE35167.1 - 0.0016 18.8 1.3 0.091 13.4 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EPE35167.1 - 0.0069 16.7 0.1 0.72 10.3 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) HET PF06985.11 EPE35168.1 - 4e-34 118.1 0.8 1.2e-33 116.6 0.3 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF3109 PF11307.8 EPE35168.1 - 0.023 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) SRR1 PF07985.12 EPE35169.1 - 1.2e-05 25.3 0.0 2.6e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 SRR1 Acetyltransf_10 PF13673.7 EPE35170.1 - 9.4e-09 35.3 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE35170.1 - 2.8e-07 30.8 0.0 5.2e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE35170.1 - 1.6e-06 28.4 0.0 2.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Tetraspanin PF00335.20 EPE35171.1 - 0.0003 20.6 2.5 0.00084 19.1 2.5 1.8 1 1 0 1 1 1 1 Tetraspanin family DUF2615 PF11027.8 EPE35171.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) PX PF00787.24 EPE35172.1 - 3e-26 91.6 0.0 3.5e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 PX domain IPK PF03770.16 EPE35173.1 - 7.1e-57 192.5 0.0 1.5e-56 191.4 0.0 1.6 1 0 0 1 1 1 1 Inositol polyphosphate kinase Myb_DNA-binding PF00249.31 EPE35175.1 - 0.0014 18.8 0.1 0.017 15.3 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EPE35177.1 - 6.9e-16 58.2 1.4 1.7e-08 34.5 0.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPE35177.1 - 5.8e-10 39.3 0.5 2.7e-05 24.3 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Glyco_hydro_16 PF00722.21 EPE35178.1 - 2.8e-46 157.2 4.6 2.8e-46 157.2 4.6 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 EPE35178.1 - 0.076 13.5 14.1 0.2 12.2 14.1 1.6 1 0 0 1 1 1 0 Chitin recognition protein adh_short_C2 PF13561.6 EPE35179.1 - 7.2e-61 205.7 3.7 8.6e-61 205.5 3.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE35179.1 - 4.8e-52 176.3 3.4 5.8e-52 176.0 3.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE35179.1 - 6.8e-16 58.7 1.9 1.2e-15 57.9 1.9 1.3 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 EPE35179.1 - 0.0052 16.2 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EPE35179.1 - 0.0071 15.8 0.2 0.68 9.3 0.2 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 EPE35179.1 - 0.008 16.2 0.7 0.03 14.3 0.3 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EPE35179.1 - 0.015 16.0 0.0 0.059 14.1 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain 3HCDH_N PF02737.18 EPE35179.1 - 0.046 13.6 0.4 0.046 13.6 0.4 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pentapeptide_4 PF13599.6 EPE35181.1 - 9.5e-06 25.7 0.6 0.031 14.4 0.2 2.4 2 0 0 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 EPE35181.1 - 0.069 12.8 0.0 11 5.7 0.1 2.6 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) DHHC PF01529.20 EPE35182.1 - 7.8e-35 119.9 7.4 7.8e-35 119.9 7.4 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.17 EPE35182.1 - 0.09 12.5 0.1 0.09 12.5 0.1 2.0 2 0 0 2 2 2 0 Yip1 domain B12D PF06522.11 EPE35183.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit PMT PF02366.18 EPE35184.1 - 6.8e-79 264.9 15.9 6.8e-79 264.9 15.9 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EPE35184.1 - 3.8e-68 229.0 11.8 3.8e-68 229.0 11.8 2.3 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EPE35184.1 - 6.9e-44 149.9 0.1 1.2e-43 149.1 0.1 1.4 1 0 0 1 1 1 1 MIR domain MFS_1 PF07690.16 EPE35185.1 - 0.006 15.6 0.0 0.0075 15.2 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1345 PF07077.11 EPE35185.1 - 0.08 12.6 0.0 0.41 10.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF5357 PF17310.2 EPE35185.1 - 0.13 10.8 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) ERCC4 PF02732.15 EPE35186.1 - 1.5e-24 87.0 0.2 3.9e-24 85.6 0.1 1.7 1 1 1 2 2 2 1 ERCC4 domain Arrestin_C PF02752.22 EPE35187.1 - 6.4e-16 59.0 0.0 3.3e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EPE35187.1 - 3.2e-13 50.0 0.0 5.5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EPE35187.1 - 0.0007 19.3 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like DUF4177 PF13783.6 EPE35187.1 - 0.012 15.9 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) ATP12 PF07542.11 EPE35188.1 - 1.1e-44 151.6 0.0 1.7e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein GMC_oxred_N PF00732.19 EPE35189.1 - 2e-54 185.0 0.0 2.7e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE35189.1 - 3.2e-30 105.5 0.0 6.9e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EPE35189.1 - 0.0037 17.4 0.0 0.0094 16.2 0.0 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE35189.1 - 0.048 13.2 0.3 0.51 9.9 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Rubis-subs-bind PF09273.11 EPE35190.1 - 2.1e-22 80.2 0.0 3.3e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EPE35190.1 - 2.7e-14 53.9 0.0 4.2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 SET domain zf-LITAF-like PF10601.9 EPE35191.1 - 8.7e-20 70.8 10.7 1.3e-19 70.2 10.7 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Glyco_hydro_18 PF00704.28 EPE35192.1 - 1.1e-40 140.3 0.6 1.7e-40 139.7 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EPE35192.1 - 2.7e-06 27.7 5.8 2.7e-06 27.7 5.8 4.2 5 1 1 6 6 6 1 Chitin recognition protein LysM PF01476.20 EPE35192.1 - 7.8e-06 25.9 0.2 7.6e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 LysM domain Herpes_pp85 PF04637.12 EPE35193.1 - 0.4 9.0 3.4 0.55 8.6 3.4 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) LysM PF01476.20 EPE35195.1 - 3.3e-05 23.8 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 EPE35195.1 - 7.3e-05 23.2 63.4 0.034 14.6 14.9 4.5 3 0 0 3 3 3 3 Chitin recognition protein FSA_C PF10479.9 EPE35195.1 - 2.2 6.3 12.7 3 5.9 12.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus PHY PF00360.20 EPE35196.1 - 6.1e-28 97.4 0.0 1.2e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Phytochrome region Response_reg PF00072.24 EPE35196.1 - 2e-15 56.9 0.0 6.1e-15 55.4 0.0 1.9 1 1 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EPE35196.1 - 4.4e-14 52.9 0.2 1.9e-13 50.9 0.1 2.2 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 EPE35196.1 - 5.1e-14 53.0 0.0 1.3e-13 51.7 0.0 1.8 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 EPE35196.1 - 2.9e-09 36.8 1.0 7.8e-09 35.4 1.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 EPE35196.1 - 3.2e-08 34.2 0.0 9.3e-08 32.7 0.0 1.9 1 0 0 1 1 1 1 PAS fold PH PF00169.29 EPE35197.1 - 0.02 15.4 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 PH domain Apolipoprotein PF01442.18 EPE35197.1 - 0.044 13.6 0.4 0.089 12.7 0.4 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Spore_II_R PF09551.10 EPE35197.1 - 7.7 7.0 6.9 7 7.1 0.3 2.6 2 1 1 3 3 3 0 Stage II sporulation protein R (spore_II_R) DUF3533 PF12051.8 EPE35198.1 - 1.5e-89 300.6 14.9 1.7e-89 300.4 14.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) TcA_TcB_BD PF18276.1 EPE35199.1 - 2.2e-60 204.2 1.5 3.6e-46 157.6 0.5 2.1 2 0 0 2 2 2 2 Tc toxin complex TcA C-terminal TcB-binding domain Zds_C PF08632.10 EPE35200.1 - 9.4e-29 98.9 1.2 1.6e-28 98.2 1.2 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Ribosomal_60s PF00428.19 EPE35200.1 - 0.37 11.4 0.0 0.37 11.4 0.0 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein VHS PF00790.19 EPE35201.1 - 1.2e-33 115.9 0.7 2.4e-33 114.9 0.7 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 EPE35201.1 - 1.3e-17 63.1 0.1 2.4e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EPE35201.1 - 9e-15 54.1 0.0 1.4e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EPE35201.1 - 2.8e-13 49.5 0.0 5.1e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 EPE35201.1 - 0.014 15.7 0.8 0.046 14.0 0.8 2.0 1 0 0 1 1 1 0 GAT domain UIM PF02809.20 EPE35201.1 - 1.6 8.9 7.8 0.13 12.2 2.9 1.9 2 0 0 2 2 2 0 Ubiquitin interaction motif Fe-ADH PF00465.19 EPE35202.1 - 3e-103 345.4 0.0 3.7e-103 345.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EPE35202.1 - 1.5e-14 54.3 0.0 1.7e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase RCC1 PF00415.18 EPE35203.1 - 4.1e-25 88.1 0.2 0.00011 22.8 0.0 4.8 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EPE35203.1 - 6.1e-11 42.5 0.0 1.9e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Ank_4 PF13637.6 EPE35203.1 - 2.3e-07 31.2 0.0 5.9e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RCC1_2 PF13540.6 EPE35203.1 - 7.9e-07 28.7 4.9 1.4e-05 24.8 0.1 3.7 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.6 EPE35203.1 - 0.004 17.5 0.0 0.11 13.1 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat AMNp_N PF10423.9 EPE35203.1 - 0.1 12.3 0.2 0.82 9.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial AMP nucleoside phosphorylase N-terminus Ank_2 PF12796.7 EPE35203.1 - 0.14 12.8 0.0 0.4 11.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF16 PF01519.16 EPE35207.1 - 0.0027 18.2 0.9 0.028 14.9 0.3 2.1 1 1 0 2 2 2 1 Protein of unknown function DUF16 HEPN_AbiU2 PF18734.1 EPE35207.1 - 0.024 14.2 0.1 0.052 13.0 0.1 1.6 1 1 0 1 1 1 0 AbiU2 DUF4806 PF16064.5 EPE35207.1 - 0.05 13.9 0.4 0.23 11.8 0.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4806) HeLo PF14479.6 EPE35207.1 - 0.055 13.3 0.9 0.12 12.2 0.9 1.7 1 1 0 1 1 1 0 Prion-inhibition and propagation Fungal_trans PF04082.18 EPE35208.1 - 2.5e-11 43.1 0.5 4.1e-11 42.4 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE35208.1 - 8.2e-10 38.6 10.6 1.3e-09 38.1 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SpoVR PF04293.13 EPE35208.1 - 0.16 10.7 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 SpoVR like protein CPSase_L_D2 PF02786.17 EPE35210.1 - 4.1e-112 372.8 0.2 7.1e-84 280.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EPE35210.1 - 8.6e-48 161.4 0.1 2.6e-47 159.8 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EPE35210.1 - 3.9e-47 160.5 0.0 8.3e-47 159.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 EPE35210.1 - 1.4e-46 158.2 0.0 3e-46 157.1 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EPE35210.1 - 2e-40 137.9 0.1 1.1e-39 135.6 0.1 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EPE35210.1 - 1.2e-30 106.7 0.0 2.8e-30 105.5 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EPE35210.1 - 2.3e-20 72.6 0.0 2e-19 69.6 0.0 2.8 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EPE35210.1 - 1.7e-18 66.9 0.4 4.6e-08 32.8 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EPE35210.1 - 3.8e-16 59.1 0.1 8.8e-08 31.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EPE35210.1 - 8.9e-10 38.4 0.0 0.00017 21.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 EPE35210.1 - 1.7e-06 27.9 0.3 0.00026 20.8 0.3 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 EPE35210.1 - 1.5e-05 25.1 0.4 0.069 13.2 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 EPE35210.1 - 5.1e-05 23.1 0.9 0.59 9.9 0.0 3.4 4 0 0 4 4 4 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.24 EPE35210.1 - 0.00074 19.4 0.1 0.17 11.7 0.0 3.9 4 0 0 4 4 4 1 DJ-1/PfpI family RimK PF08443.11 EPE35210.1 - 0.0014 18.3 0.0 2.6 7.6 0.0 2.8 2 0 0 2 2 2 2 RimK-like ATP-grasp domain AKAP7_NLS PF10469.9 EPE35210.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain Glyco_hydro_6 PF01341.17 EPE35213.1 - 4.9e-97 325.3 0.0 6.6e-97 324.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 S1-P1_nuclease PF02265.16 EPE35214.1 - 6.4e-73 245.7 0.0 7.3e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Peptidase_M24 PF00557.24 EPE35215.1 - 6.7e-08 32.5 0.0 9.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 TPR_12 PF13424.6 EPE35216.1 - 2.8e-51 171.7 35.0 1.3e-14 54.2 0.3 9.9 5 2 4 10 10 9 8 Tetratricopeptide repeat TPR_10 PF13374.6 EPE35216.1 - 6.1e-46 153.1 31.6 1.7e-05 24.5 0.0 12.8 12 1 1 13 13 13 9 Tetratricopeptide repeat NB-ARC PF00931.22 EPE35216.1 - 5.9e-14 51.9 0.1 1.3e-13 50.7 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.17 EPE35216.1 - 5.4e-09 35.5 24.1 0.019 15.1 0.0 10.6 12 0 0 12 12 11 2 Tetratricopeptide repeat AAA_16 PF13191.6 EPE35216.1 - 2.1e-08 34.7 0.8 2.9e-07 31.0 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain TPR_MalT PF17874.1 EPE35216.1 - 1.3e-07 31.3 13.1 0.00055 19.4 5.8 4.3 2 1 1 4 4 4 3 MalT-like TPR region TPR_7 PF13176.6 EPE35216.1 - 3.7e-06 26.6 14.0 0.17 12.0 0.2 7.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EPE35216.1 - 0.00016 21.3 14.4 0.78 9.7 0.1 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPE35216.1 - 0.00071 20.0 5.2 9.9 6.8 0.1 5.8 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPE35216.1 - 0.006 17.2 15.0 21 5.9 0.1 7.7 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPE35216.1 - 0.027 15.3 16.7 37 5.5 0.0 8.2 9 1 1 10 10 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 EPE35216.1 - 0.034 14.5 2.6 1.8e+02 2.8 0.0 6.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.6 EPE35216.1 - 0.041 14.1 22.7 0.13 12.6 0.1 7.6 11 0 0 11 11 7 0 Tetratricopeptide repeat TPR_20 PF14561.6 EPE35216.1 - 0.26 11.7 2.5 6.4 7.2 0.8 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPE35216.1 - 1.9 9.3 4.7 77 4.2 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF676 PF05057.14 EPE35217.1 - 0.00011 21.8 0.0 0.00045 19.8 0.0 1.9 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EPE35217.1 - 0.00017 22.3 0.0 0.00028 21.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE35217.1 - 0.00077 18.8 0.1 0.0017 17.7 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LCAT PF02450.15 EPE35217.1 - 0.0029 16.8 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF726 PF05277.12 EPE35217.1 - 0.0059 15.6 0.0 0.012 14.6 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF726) DUF829 PF05705.14 EPE35217.1 - 0.026 14.4 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Ser_hydrolase PF06821.13 EPE35217.1 - 0.045 13.6 0.0 0.092 12.6 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.13 EPE35217.1 - 0.064 13.0 0.0 0.14 11.8 0.0 1.6 1 1 0 1 1 1 0 PGAP1-like protein OrsD PF12013.8 EPE35218.1 - 2.7e-12 47.2 0.5 1.1e-11 45.2 0.0 2.3 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D GFA PF04828.14 EPE35219.1 - 2.7e-19 69.3 0.2 3.7e-19 68.8 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 EPE35219.1 - 0.39 10.9 4.2 2.7 8.2 0.2 2.2 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like FAA_hydrolase PF01557.18 EPE35220.1 - 1.1e-52 178.9 0.0 1.3e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ADH_zinc_N PF00107.26 EPE35224.1 - 2.3e-11 43.8 0.0 4.3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE35224.1 - 5.1e-07 29.5 2.0 9.5e-06 25.5 1.8 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EPE35224.1 - 0.04 15.0 0.0 0.1 13.6 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Pkinase PF00069.25 EPE35225.1 - 0.00057 19.3 0.0 0.00057 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SKA1 PF07160.12 EPE35226.1 - 0.021 14.7 1.5 0.037 13.9 1.5 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 EF-hand_2 PF09068.11 EPE35226.1 - 0.12 12.5 0.4 0.28 11.4 0.2 1.6 2 0 0 2 2 2 0 EF hand Tnp_22_dsRBD PF17490.2 EPE35226.1 - 0.13 12.2 0.1 27 4.9 0.0 2.6 2 0 0 2 2 2 0 L1 transposable element dsRBD-like domain Pyr_redox_2 PF07992.14 EPE35227.1 - 9.9e-14 51.2 0.0 1.2e-12 47.7 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE35227.1 - 0.00035 19.8 0.1 0.011 14.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EPE35227.1 - 0.022 14.0 0.3 0.15 11.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE35227.1 - 0.075 11.7 0.1 0.17 10.5 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 EPE35227.1 - 0.1 12.8 2.9 2.4 8.4 0.0 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Ras PF00071.22 EPE35228.1 - 1.2e-44 151.7 0.0 1.7e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE35228.1 - 2.3e-30 105.3 0.0 3.5e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE35228.1 - 4.7e-11 42.4 0.0 1.5e-10 40.8 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPE35228.1 - 7.8e-05 22.7 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EPE35228.1 - 0.00012 21.5 0.0 0.00017 21.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EPE35228.1 - 0.002 17.7 0.0 0.011 15.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EPE35228.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 EPE35228.1 - 0.011 15.9 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EPE35228.1 - 0.013 15.7 0.1 0.13 12.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EPE35228.1 - 0.018 14.8 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EPE35228.1 - 0.019 15.3 0.1 0.057 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 EPE35228.1 - 0.024 14.9 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EPE35228.1 - 0.03 14.8 0.2 0.092 13.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 EPE35228.1 - 0.035 14.0 0.0 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 EPE35228.1 - 0.037 13.9 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EPE35228.1 - 0.05 13.4 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain adh_short PF00106.25 EPE35229.1 - 6.4e-38 130.2 0.1 7.8e-38 129.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE35229.1 - 5.5e-29 101.4 0.1 6.5e-29 101.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE35229.1 - 1.6e-10 41.2 0.2 3.8e-10 40.0 0.2 1.7 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EPE35229.1 - 0.078 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EPE35229.1 - 0.14 12.0 0.1 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding Mannosidase_ig PF17786.1 EPE35230.1 - 2.1e-15 57.1 0.2 7.5e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EPE35230.1 - 2.2e-11 44.4 0.1 1.4e-10 41.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 EPE35230.1 - 0.0014 17.8 0.2 0.0039 16.3 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 EPE35230.1 - 0.003 17.3 0.1 0.013 15.2 0.0 2.1 2 0 0 2 2 2 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 EPE35230.1 - 0.02 14.8 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain bZIP_2 PF07716.15 EPE35232.1 - 0.00011 22.2 8.7 0.00024 21.1 8.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EPE35232.1 - 0.00019 21.5 8.9 0.00044 20.3 8.9 1.7 1 1 0 1 1 1 1 bZIP transcription factor FUSC-like PF12805.7 EPE35232.1 - 0.055 12.6 0.4 0.083 12.0 0.4 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS D5_N PF08706.11 EPE35232.1 - 0.84 9.9 4.3 1.3 9.3 4.3 1.5 1 1 0 1 1 1 0 D5 N terminal like NAM-associated PF14303.6 EPE35232.1 - 2.3 8.9 16.0 4.1 8.1 15.7 1.6 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain bZIP_Maf PF03131.17 EPE35232.1 - 4.1 8.0 9.4 0.49 10.9 3.7 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor SET PF00856.28 EPE35233.1 - 1.1e-11 45.4 0.0 6.7e-11 42.9 0.0 2.1 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EPE35233.1 - 0.51 10.5 6.1 1.2 9.2 6.1 1.7 1 1 0 1 1 1 0 MYND finger zf-FLZ PF04570.14 EPE35233.1 - 1.8 8.1 6.6 23 4.6 7.4 2.3 2 1 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 DUF3449 PF11931.8 EPE35235.1 - 2.7e-77 258.8 0.0 2.7e-77 258.8 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EPE35235.1 - 1.7e-26 92.5 1.9 9.1e-26 90.2 0.4 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EPE35235.1 - 2.1e-12 46.7 0.1 4.4e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 EPE35235.1 - 6.9e-09 35.8 4.7 1.6e-07 31.4 1.2 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPE35235.1 - 3.3e-08 33.6 3.1 6.7e-06 26.3 0.8 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type PRP9_N PF16958.5 EPE35235.1 - 1.8e-05 24.8 5.8 0.023 14.7 1.3 2.8 1 1 1 2 2 2 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_2 PF12756.7 EPE35235.1 - 0.00045 20.5 0.9 0.048 14.0 0.2 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EPE35235.1 - 0.084 13.8 3.8 6.5 7.9 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger DUF951 PF06107.11 EPE35235.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) Desulfoferrod_N PF06397.12 EPE35235.1 - 0.36 10.5 1.3 0.72 9.5 1.3 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain zf-C2H2 PF00096.26 EPE35235.1 - 2.4 8.8 4.1 21 5.8 0.2 2.9 3 0 0 3 3 2 0 Zinc finger, C2H2 type DEAD PF00270.29 EPE35236.1 - 1.3e-41 142.3 0.1 2.2e-41 141.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE35236.1 - 3.6e-33 114.2 0.0 1.1e-32 112.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EPE35236.1 - 0.00038 20.2 0.0 0.00055 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPE35236.1 - 0.0019 18.6 0.1 0.017 15.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EPE35236.1 - 0.0026 17.8 0.0 0.0051 16.8 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 EPE35236.1 - 0.046 13.7 0.2 0.16 11.9 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 EPE35236.1 - 0.088 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 EPE35236.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Helicase DUF5393 PF17371.2 EPE35236.1 - 0.12 10.4 0.0 0.2 9.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) BRCT PF00533.26 EPE35237.1 - 8.1e-08 32.5 0.0 2e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EPE35237.1 - 1.9e-06 28.2 0.0 5.7e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EPE35237.1 - 0.016 15.1 0.0 0.045 13.6 0.0 1.8 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 EPE35237.1 - 0.021 14.9 0.1 0.58 10.3 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Nodulin_late PF07127.11 EPE35238.1 - 0.0025 18.1 3.6 0.53 10.7 0.1 2.3 2 0 0 2 2 2 2 Late nodulin protein Squash PF00299.18 EPE35238.1 - 0.038 14.0 14.7 0.42 10.7 3.6 2.4 2 0 0 2 2 2 0 Squash family serine protease inhibitor Gamma-thionin PF00304.20 EPE35238.1 - 0.41 11.0 17.8 2.1 8.7 3.3 2.4 2 0 0 2 2 2 0 Gamma-thionin family PALP PF00291.25 EPE35239.1 - 4.5e-44 151.0 0.0 5e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.18 EPE35239.1 - 0.18 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 LytB protein ADH_N PF08240.12 EPE35240.1 - 1.2e-29 102.4 1.4 1.7e-29 101.8 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE35240.1 - 1.4e-23 83.3 0.2 2.8e-23 82.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EPE35240.1 - 1.4e-08 34.5 0.8 3e-08 33.4 0.8 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EPE35240.1 - 0.0001 23.3 0.0 0.00036 21.6 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPE35240.1 - 0.0026 17.1 2.2 0.0039 16.5 2.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EPE35240.1 - 0.0061 15.8 1.2 0.018 14.3 1.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EPE35240.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TmoB PF06234.12 EPE35240.1 - 0.024 14.7 0.4 0.31 11.2 0.0 2.7 3 0 0 3 3 3 0 Toluene-4-monooxygenase system protein B (TmoB) FtsJ PF01728.19 EPE35240.1 - 0.028 14.5 0.0 0.057 13.5 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EPE35240.1 - 0.033 14.9 0.1 0.25 12.1 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain HI0933_like PF03486.14 EPE35240.1 - 0.1 11.3 0.6 0.17 10.5 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein AMP-binding PF00501.28 EPE35241.1 - 1.3e-87 294.2 0.0 1.9e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Beta-lactamase PF00144.24 EPE35242.1 - 1.8e-29 103.1 0.0 1.4e-28 100.1 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase DUF3430 PF11912.8 EPE35243.1 - 0.039 14.0 0.0 0.045 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) INSIG PF07281.12 EPE35244.1 - 2.1e-78 262.8 0.1 2.6e-78 262.5 0.1 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) GDPD PF03009.17 EPE35245.1 - 7.9e-18 65.1 0.0 1.1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family G-patch_2 PF12656.7 EPE35246.1 - 8.6e-20 70.6 2.7 1.5e-19 69.8 0.3 2.8 2 0 0 2 2 2 1 G-patch domain Myb_DNA-bind_6 PF13921.6 EPE35247.1 - 4.9e-11 42.7 1.1 4.9e-11 42.7 1.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain HSA PF07529.13 EPE35247.1 - 2.2e-10 40.7 0.0 2.2e-10 40.7 0.0 3.4 3 0 0 3 3 3 1 HSA Myb_DNA-binding PF00249.31 EPE35247.1 - 8.1e-05 22.7 1.1 0.00022 21.3 1.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_Cef PF11831.8 EPE35248.1 - 2.7e-48 164.6 4.7 2.7e-48 164.6 4.7 2.7 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EPE35248.1 - 1.2e-21 76.6 4.5 2.9e-10 40.2 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPE35248.1 - 9.1e-20 70.7 4.7 6.4e-13 48.7 1.4 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.6 EPE35248.1 - 0.061 13.2 0.5 0.27 11.1 0.0 2.3 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Rap1_C PF11626.8 EPE35248.1 - 0.18 11.9 0.0 0.18 11.9 0.0 3.3 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Hexokinase_1 PF00349.21 EPE35249.1 - 1.5e-46 158.9 0.0 2.1e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EPE35249.1 - 7e-45 153.3 0.0 9.8e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase GILT PF03227.16 EPE35250.1 - 5.1e-18 65.3 0.1 8.2e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DcpS PF05652.12 EPE35251.1 - 5.9e-36 123.5 0.0 1.5e-35 122.1 0.0 1.8 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 EPE35251.1 - 9e-14 51.9 0.0 1.8e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding RNA_pol PF00940.19 EPE35253.1 - 5.2e-183 608.6 0.0 7.3e-183 608.1 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EPE35253.1 - 2.1e-96 323.3 4.5 3e-96 322.7 4.5 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Cnl2_NKP2 PF09447.10 EPE35255.1 - 1.2e-27 95.8 0.6 2.6e-27 94.7 0.6 1.6 1 0 0 1 1 1 1 Cnl2/NKP2 family protein MRG PF05712.13 EPE35256.1 - 2.3e-59 200.1 0.0 3.7e-59 199.4 0.0 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EPE35256.1 - 4.8e-07 29.6 1.0 9.7e-07 28.6 1.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF742 PF05331.11 EPE35256.1 - 0.065 13.0 0.1 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF742) RmuC PF02646.16 EPE35256.1 - 0.073 12.2 0.1 0.65 9.1 0.0 2.1 2 0 0 2 2 2 0 RmuC family Ribosomal_L30 PF00327.20 EPE35257.1 - 3.3e-08 33.3 0.2 4e-08 33.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Sec6 PF06046.13 EPE35258.1 - 1.5e-174 581.5 9.3 2.3e-174 581.0 9.3 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 PEP-utilisers_N PF05524.13 EPE35258.1 - 0.025 14.8 3.3 0.81 9.9 0.2 2.8 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF755 PF05501.11 EPE35258.1 - 0.04 14.2 0.2 0.089 13.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) OmdA PF13376.6 EPE35258.1 - 0.057 13.4 0.0 0.24 11.5 0.0 2.1 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated SPATA19 PF15212.6 EPE35258.1 - 0.13 12.4 0.6 0.39 10.9 0.6 1.8 1 0 0 1 1 1 0 Spermatogenesis-associated protein 19, mitochondrial Vps53_N PF04100.12 EPE35258.1 - 0.23 10.4 10.0 0.014 14.3 3.5 2.2 2 1 0 2 2 2 0 Vps53-like, N-terminal NPV_P10 PF05531.12 EPE35258.1 - 0.26 11.8 2.7 32 5.1 0.0 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Aldo_ket_red PF00248.21 EPE35259.1 - 3.4e-65 220.1 0.0 5.1e-65 219.6 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family CENP-Q PF13094.6 EPE35259.1 - 7.8e-35 120.5 3.2 7.8e-35 120.5 3.2 2.5 3 0 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit SPO22 PF08631.10 EPE35260.1 - 1.6e-63 214.8 5.4 1.6e-63 214.8 5.4 2.3 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.17 EPE35260.1 - 0.16 12.1 0.0 0.16 12.1 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EPE35260.1 - 0.18 12.5 0.8 38 5.0 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPE35260.1 - 0.37 11.1 9.0 0.17 12.2 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_28 PF00295.17 EPE35261.1 - 5.1e-117 390.5 21.9 6e-117 390.3 21.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Amidohydro_1 PF01979.20 EPE35262.1 - 1.2e-10 41.3 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPE35262.1 - 5e-09 36.1 0.3 5.3e-08 32.8 0.2 2.4 2 1 1 3 3 3 1 Amidohydrolase family C2 PF00168.30 EPE35263.1 - 2.8e-30 104.7 0.1 2.1e-18 66.5 0.0 2.8 3 0 0 3 3 3 2 C2 domain HET PF06985.11 EPE35266.1 - 2.4e-16 60.4 0.5 2.4e-16 60.4 0.5 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Abhydrolase_1 PF00561.20 EPE35267.1 - 1.2e-44 153.0 0.0 2.5e-44 151.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EPE35267.1 - 0.00075 19.2 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase zf-RING_6 PF14835.6 EPE35267.1 - 0.12 12.2 0.7 0.29 11.0 0.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein AMP-binding PF00501.28 EPE35269.1 - 1.1e-78 264.7 0.0 1.5e-78 264.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE35269.1 - 1.5e-14 54.7 0.5 3.8e-14 53.4 0.5 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SLC35F PF06027.12 EPE35270.1 - 9.7e-101 337.2 26.5 1.2e-100 336.9 26.5 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EPE35270.1 - 4.2e-07 29.2 7.8 6.8e-07 28.5 7.8 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EPE35270.1 - 0.00021 21.5 38.3 0.035 14.3 15.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family FUSC-like PF12805.7 EPE35270.1 - 1.6 7.7 0.0 1.6 7.7 0.0 2.8 3 0 0 3 3 3 0 FUSC-like inner membrane protein yccS ubiquitin PF00240.23 EPE35271.1 - 0.012 15.3 0.3 0.025 14.4 0.3 1.5 1 0 0 1 1 1 0 Ubiquitin family DUF1631 PF07793.11 EPE35271.1 - 0.043 12.3 1.6 0.054 11.9 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DNA_pol_phi PF04931.13 EPE35271.1 - 0.094 10.8 7.5 0.15 10.2 7.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF1115 PF06544.12 EPE35272.1 - 0.033 14.3 0.1 0.035 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) GFA PF04828.14 EPE35273.1 - 1.7e-25 89.1 0.1 2.3e-25 88.8 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme K_oxygenase PF13434.6 EPE35274.1 - 1.6e-112 376.0 0.0 1.9e-112 375.8 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EPE35274.1 - 4e-09 36.1 0.0 5.4e-06 25.8 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE35274.1 - 2.3e-06 27.1 0.0 0.00013 21.3 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPE35274.1 - 6.9e-05 22.9 0.0 0.0026 17.8 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EPE35274.1 - 0.00087 19.0 0.0 2.4 7.6 0.1 3.3 2 1 0 3 3 3 1 FAD dependent oxidoreductase Condensation PF00668.20 EPE35275.1 - 2.2e-18 66.2 0.0 6.1e-16 58.1 0.0 2.1 1 1 0 1 1 1 1 Condensation domain Asp PF00026.23 EPE35276.1 - 2.6e-60 204.5 10.6 3.2e-60 204.2 10.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPE35276.1 - 2.9e-05 24.4 9.8 0.00069 19.9 1.2 3.1 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EPE35276.1 - 0.00043 20.9 4.9 0.016 15.9 1.3 3.3 2 2 0 2 2 2 1 Aspartyl protease LprI PF07007.12 EPE35277.1 - 0.034 14.8 2.5 0.067 13.8 2.3 1.7 1 1 0 1 1 1 0 Lysozyme inhibitor LprI EBP50_C PF09007.11 EPE35277.1 - 1.5 9.8 9.9 2 9.4 9.3 1.5 1 1 0 1 1 1 0 EBP50, C-terminal Syntaxin-6_N PF09177.11 EPE35277.1 - 6.1 7.5 12.1 0.84 10.2 0.8 2.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Collagen PF01391.18 EPE35281.1 - 1.4e-24 85.6 113.3 1.7e-08 34.1 27.4 4.8 2 1 3 5 5 5 4 Collagen triple helix repeat (20 copies) WSC PF01822.19 EPE35281.1 - 1.3e-16 60.6 16.2 2.1e-16 59.9 16.2 1.3 1 0 0 1 1 1 1 WSC domain ABC_membrane PF00664.23 EPE35282.1 - 2.3e-109 365.3 34.5 4.3e-55 187.3 18.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EPE35282.1 - 2.4e-69 232.1 0.0 4.1e-33 114.8 0.1 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EPE35282.1 - 1e-13 51.2 0.0 0.00037 20.0 0.0 3.8 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EPE35282.1 - 4e-07 30.6 2.0 0.019 15.3 0.0 3.5 3 2 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EPE35282.1 - 1.4e-06 28.3 0.0 0.75 9.7 0.0 3.5 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 EPE35282.1 - 2.3e-06 27.2 1.7 0.0071 16.1 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EPE35282.1 - 2.9e-05 23.0 2.7 0.015 14.1 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 EPE35282.1 - 0.00011 22.5 3.1 0.19 12.0 0.1 4.1 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EPE35282.1 - 0.00011 22.0 0.0 0.89 9.2 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EPE35282.1 - 0.00031 20.4 0.3 0.17 11.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 EPE35282.1 - 0.0021 17.3 0.0 1.9 7.6 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_21 PF13304.6 EPE35282.1 - 0.0026 17.6 2.7 3.4 7.4 0.0 3.8 5 0 0 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EPE35282.1 - 0.0026 17.5 3.3 1.4 8.6 0.1 3.8 4 0 0 4 4 4 1 AAA domain DUF87 PF01935.17 EPE35282.1 - 0.0029 17.7 2.3 2.8 8.0 0.0 3.4 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_28 PF13521.6 EPE35282.1 - 0.0029 17.8 0.6 0.42 10.8 0.1 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EPE35282.1 - 0.0031 17.7 2.1 4.7 7.5 0.4 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 EPE35282.1 - 0.008 15.5 0.0 4 6.7 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 EPE35282.1 - 0.0094 15.5 0.0 3.8 7.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 EPE35282.1 - 0.013 16.0 0.7 5.2 7.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EPE35282.1 - 0.016 15.0 0.1 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EPE35282.1 - 0.028 14.2 0.0 0.78 9.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EPE35282.1 - 0.033 14.3 0.0 11 6.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EPE35282.1 - 0.066 12.4 0.2 4 6.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 EPE35282.1 - 0.088 12.8 2.7 12 5.9 0.0 3.5 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EPE35282.1 - 0.11 12.4 0.1 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain CsgA PF17334.2 EPE35282.1 - 0.21 12.3 0.7 0.68 10.7 0.0 2.2 2 0 0 2 2 1 0 Minor curli fiber component A AAA_23 PF13476.6 EPE35282.1 - 1.9 8.9 6.4 9.9 6.6 0.0 3.6 4 1 0 4 4 3 0 AAA domain MMR_HSR1 PF01926.23 EPE35282.1 - 2.4 8.3 4.6 23 5.1 0.0 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase IL28A PF15177.6 EPE35283.1 - 0.071 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Interleukin-28A TRI12 PF06609.13 EPE35284.1 - 5.1e-63 213.4 19.3 6.2e-63 213.2 19.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EPE35284.1 - 1.3e-21 76.9 37.1 5.2e-21 74.9 33.0 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily LapA_dom PF06305.11 EPE35284.1 - 0.11 12.3 0.0 0.11 12.3 0.0 4.1 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Clr5 PF14420.6 EPE35285.1 - 1.3e-15 57.4 2.3 3.1e-15 56.1 2.3 1.7 1 0 0 1 1 1 1 Clr5 domain RP-C_C PF11800.8 EPE35285.1 - 0.77 9.8 5.4 0.38 10.8 0.4 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region MFS_1 PF07690.16 EPE35288.1 - 3.2e-39 134.8 35.7 3.2e-39 134.8 35.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE35288.1 - 1.7e-11 43.7 6.5 1.7e-11 43.7 6.5 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter UbiA PF01040.18 EPE35289.1 - 2.5e-58 197.3 13.9 2.5e-58 197.3 13.9 1.5 1 1 1 2 2 2 1 UbiA prenyltransferase family Enterotoxin_HS1 PF08090.11 EPE35289.1 - 0.014 15.3 1.7 0.014 15.3 1.7 2.2 2 0 0 2 2 2 0 Heat stable E.coli enterotoxin 1 Myb_DNA-binding PF00249.31 EPE35290.1 - 2.6e-05 24.3 0.0 8.4e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPE35290.1 - 0.00038 20.6 0.2 0.0017 18.5 0.0 2.2 2 1 0 2 2 2 1 Myb-like DNA-binding domain Sugar_tr PF00083.24 EPE35291.1 - 6.6e-116 387.8 25.5 9.1e-116 387.4 25.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE35291.1 - 1.7e-22 79.8 39.9 9.3e-18 64.3 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rad50_zn_hook PF04423.14 EPE35292.1 - 0.0019 18.0 9.1 0.098 12.5 0.0 4.8 4 1 1 5 5 5 2 Rad50 zinc hook motif Lar_restr_allev PF14354.6 EPE35292.1 - 0.0089 16.4 1.8 0.0089 16.4 1.8 4.5 2 2 2 4 4 4 1 Restriction alleviation protein Lar Prok-RING_4 PF14447.6 EPE35292.1 - 0.31 11.0 3.0 28 4.7 0.1 3.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 Glyco_hydro_76 PF03663.14 EPE35293.1 - 3.9e-138 461.0 7.7 4.6e-138 460.7 7.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Ank_2 PF12796.7 EPE35294.1 - 1.8e-33 115.0 9.6 1.2e-10 41.8 0.1 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE35294.1 - 2.5e-30 104.4 4.9 4e-11 43.2 0.1 6.0 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE35294.1 - 1.1e-27 93.0 8.0 7.2e-05 22.9 0.0 9.2 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 EPE35294.1 - 2.7e-20 72.1 11.5 4.1e-06 27.0 0.2 6.9 4 3 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EPE35294.1 - 2e-11 43.8 14.0 0.13 12.8 0.7 7.8 7 1 1 8 8 8 3 Ankyrin repeat MOZART1 PF12554.8 EPE35294.1 - 0.17 11.7 0.7 15 5.5 0.1 3.0 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated tRNA-synt_2 PF00152.20 EPE35297.1 - 1.8e-84 283.5 0.0 2.3e-84 283.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EPE35297.1 - 0.01 15.3 0.0 0.29 10.6 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) ANTH PF07651.16 EPE35298.1 - 1.8e-70 237.1 1.9 2.3e-70 236.7 1.9 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 EPE35298.1 - 1e-09 38.5 0.0 1.7e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 ENTH domain MAT1 PF06391.13 EPE35299.1 - 5.6e-35 121.0 8.8 6.7e-35 120.8 8.8 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EPE35299.1 - 6.3e-30 102.8 8.0 9.7e-30 102.2 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE35299.1 - 0.00035 20.4 5.0 0.00076 19.3 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE35299.1 - 0.00061 19.6 4.3 0.0013 18.5 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EPE35299.1 - 0.0028 17.2 1.6 0.006 16.2 1.6 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 EPE35299.1 - 0.012 15.9 6.5 0.023 15.0 6.5 1.5 1 0 0 1 1 1 0 Ring finger domain DUF3797 PF12677.7 EPE35299.1 - 0.075 12.9 3.7 0.19 11.6 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) zf-RING_5 PF14634.6 EPE35299.1 - 0.11 12.4 7.8 0.38 10.7 8.0 1.8 1 1 1 2 2 2 0 zinc-RING finger domain DUF1682 PF07946.14 EPE35299.1 - 0.35 10.0 9.4 0.55 9.4 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) zf-RING_4 PF14570.6 EPE35299.1 - 0.48 10.2 8.2 14 5.5 9.4 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 EPE35299.1 - 1.1 9.2 5.0 1.7 8.6 2.6 2.4 2 1 0 2 2 2 0 zf-RING of BARD1-type protein DASH_Spc19 PF08287.11 EPE35299.1 - 2 8.3 11.7 3.9 7.4 11.7 1.4 1 0 0 1 1 1 0 Spc19 Prok-RING_4 PF14447.6 EPE35299.1 - 3.2 7.7 7.9 43 4.1 8.2 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 CS PF04969.16 EPE35300.1 - 7.4e-18 65.3 0.2 1.5e-17 64.4 0.2 1.5 1 0 0 1 1 1 1 CS domain Ribophorin_II PF05817.14 EPE35301.1 - 7.8e-31 107.3 0.2 9.4e-31 107.0 0.2 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II TauD PF02668.16 EPE35302.1 - 2.9e-54 184.7 0.1 3.5e-54 184.4 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3336 PF11815.8 EPE35303.1 - 2.7e-32 111.4 1.0 4.5e-32 110.6 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EPE35303.1 - 9.1e-20 71.7 0.0 1.9e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase SR-25 PF10500.9 EPE35304.1 - 2.8 7.5 9.5 4.5 6.8 9.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Polysacc_deac_1 PF01522.21 EPE35307.1 - 3.7e-16 59.2 0.0 6.4e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase HAD_2 PF13419.6 EPE35309.1 - 2.8e-10 40.6 0.0 7.1e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPE35309.1 - 3.9e-07 30.6 0.0 1.7e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DarA_C PF18789.1 EPE35310.1 - 0.0026 18.1 0.0 0.0049 17.2 0.0 1.4 1 0 0 1 1 1 1 Defence against restriction A C-terminal Dynamin_N PF00350.23 EPE35312.1 - 3.5e-30 105.3 0.0 4.9e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EPE35312.1 - 7.1e-05 22.9 0.1 0.00027 21.0 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AviRa PF11599.8 EPE35312.1 - 0.0036 16.8 0.1 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 RRNA methyltransferase AviRa AAA_28 PF13521.6 EPE35312.1 - 0.02 15.1 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EPE35312.1 - 0.023 14.2 0.1 0.84 9.2 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.16 EPE35312.1 - 0.037 13.3 0.1 5.5 6.3 0.0 2.3 2 0 0 2 2 2 0 AIG1 family Dynamin_M PF01031.20 EPE35313.1 - 3.5e-05 23.2 0.0 5.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Ribosomal_L16 PF00252.18 EPE35315.1 - 1.5e-44 151.2 0.1 2e-44 150.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.26 EPE35316.1 - 1e-25 89.3 0.0 1.1e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3450 PF11932.8 EPE35317.1 - 0.0062 15.9 24.1 0.41 9.9 17.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EPE35317.1 - 1.5 9.0 21.8 0.62 10.2 9.7 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family FapA PF03961.13 EPE35317.1 - 3.2 6.3 15.8 0.44 9.1 11.2 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A ATG16 PF08614.11 EPE35317.1 - 4.5 7.4 34.8 1.1 9.5 22.4 3.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 EPE35317.1 - 8.7 6.4 25.6 0.4 10.8 16.1 3.1 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Collagen PF01391.18 EPE35318.1 - 0.0019 17.9 8.1 0.0039 16.9 8.1 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF5639 PF18690.1 EPE35319.1 - 0.015 15.4 0.0 0.018 15.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5639) S4 PF01479.25 EPE35320.1 - 1.1e-11 44.3 0.0 2.4e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 EPE35320.1 - 2e-10 41.4 0.1 2.8e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain ETC_C1_NDUFA5 PF04716.14 EPE35320.1 - 0.074 12.9 0.0 12 5.8 0.0 2.5 1 1 1 2 2 2 0 ETC complex I subunit conserved region Ribosomal_S18 PF01084.20 EPE35321.1 - 4.9e-10 39.5 0.1 9.9e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 PRP1_N PF06424.12 EPE35322.1 - 1.8e-52 177.7 6.6 4.4e-52 176.4 6.6 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EPE35322.1 - 2.9e-30 102.3 34.6 8.8e-05 23.0 0.1 14.4 4 4 11 15 15 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 EPE35322.1 - 1.1e-25 89.9 16.5 2.6e-08 34.3 0.4 10.4 5 3 5 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 EPE35322.1 - 7.4e-15 55.3 18.9 3.5e-05 24.4 0.1 7.0 7 1 1 8 8 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EPE35322.1 - 1.1e-12 47.0 14.4 0.72 10.1 0.0 10.1 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 EPE35322.1 - 1.4e-11 43.6 0.1 1 9.8 0.0 8.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPE35322.1 - 1.2e-10 41.1 5.4 4.9 7.8 0.0 9.8 9 1 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 EPE35322.1 - 1.7e-08 34.0 22.3 0.00017 20.9 8.5 5.8 2 2 2 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EPE35322.1 - 2.3e-07 30.4 0.5 2 8.4 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EPE35322.1 - 3.9e-07 29.7 7.3 0.82 9.4 0.1 7.4 6 1 1 7 7 7 1 TPR repeat NARP1 PF12569.8 EPE35322.1 - 1.5e-06 27.4 9.9 0.031 13.2 0.0 5.8 3 1 3 6 6 6 1 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 EPE35322.1 - 1.2e-05 25.4 7.5 0.0083 16.2 0.1 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_21 PF09976.9 EPE35322.1 - 3.2e-05 23.7 12.5 0.012 15.3 0.8 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 EPE35322.1 - 4.6e-05 23.8 10.9 67 4.4 0.1 9.4 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPE35322.1 - 7.3e-05 23.0 3.5 1.4 9.2 0.0 6.3 6 1 0 6 6 6 1 Tetratricopeptide repeat Suf PF05843.14 EPE35322.1 - 0.00038 20.5 0.1 8.1 6.3 0.0 4.4 4 1 0 5 5 5 0 Suppressor of forked protein (Suf) Wzy_C_2 PF11846.8 EPE35322.1 - 0.0064 16.4 6.7 1.6 8.6 0.7 4.7 3 1 2 5 5 5 1 Virulence factor membrane-bound polymerase, C-terminal DUF3808 PF10300.9 EPE35322.1 - 0.017 13.8 1.8 10 4.7 0.0 3.9 4 1 0 5 5 5 0 Protein of unknown function (DUF3808) NRDE-2 PF08424.10 EPE35322.1 - 0.026 13.6 24.1 0.13 11.4 0.1 5.2 4 1 0 5 5 5 0 NRDE-2, necessary for RNA interference ZNRF_3_ecto PF18212.1 EPE35322.1 - 0.027 14.5 0.3 4.5 7.3 0.0 4.1 4 0 0 4 4 4 0 ZNRF-3 Ectodomain AdenylateSensor PF16579.5 EPE35322.1 - 0.028 14.9 0.3 28 5.2 0.0 3.7 2 1 2 4 4 3 0 Adenylate sensor of SNF1-like protein kinase TPR_7 PF13176.6 EPE35322.1 - 0.042 13.9 0.4 44 4.4 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat EntA_Immun PF08951.10 EPE35322.1 - 2.8 8.4 4.3 21 5.5 0.1 3.7 3 1 1 4 4 4 0 Enterocin A Immunity Glyco_hydro_26 PF02156.15 EPE35323.1 - 1.9e-12 47.3 0.2 2.8e-12 46.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 zf-CCCH_3 PF15663.5 EPE35323.1 - 0.041 14.1 0.1 0.077 13.2 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger containing family DUF2523 PF10734.9 EPE35323.1 - 0.088 13.4 1.7 0.13 12.8 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2523) YkuD PF03734.14 EPE35325.1 - 0.18 12.2 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain DUF3824 PF12868.7 EPE35326.1 - 2e-15 57.7 52.2 1.5e-11 45.2 6.6 12.2 6 3 7 13 13 13 6 Domain of unknwon function (DUF3824) PPR_3 PF13812.6 EPE35328.1 - 4.9e-08 32.9 1.0 0.23 11.6 0.0 5.5 5 1 1 6 6 6 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 EPE35328.1 - 7e-07 29.3 0.8 3.3 8.0 0.0 5.9 5 1 1 6 6 6 2 PPR repeat family PPR_long PF17177.4 EPE35328.1 - 4.5e-05 22.9 0.0 0.036 13.4 0.0 2.7 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EPE35328.1 - 0.00017 21.6 1.4 43 4.7 0.0 6.7 8 0 0 8 8 8 0 PPR repeat TPR_19 PF14559.6 EPE35328.1 - 0.057 13.9 0.4 8.4 7.0 0.0 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat PUF PF00806.19 EPE35329.1 - 7.7e-12 44.2 0.0 0.09 12.5 0.0 7.4 8 0 0 8 8 8 4 Pumilio-family RNA binding repeat Piwi PF02171.17 EPE35330.1 - 2.6e-58 197.6 0.9 3.8e-39 134.7 0.0 2.3 1 1 1 2 2 2 2 Piwi domain ArgoN PF16486.5 EPE35330.1 - 1.2e-20 74.5 0.1 5.1e-20 72.5 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EPE35330.1 - 6.9e-15 54.5 0.0 1.7e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EPE35330.1 - 1e-11 45.0 0.0 2.4e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 EPE35330.1 - 1.5e-11 44.3 0.2 2.7e-11 43.4 0.2 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EPE35330.1 - 5.9e-07 29.7 0.0 2.8e-06 27.5 0.0 2.1 1 0 0 1 1 1 1 Mid domain of argonaute ATG7_N PF16420.5 EPE35332.1 - 1.4e-109 366.4 0.0 1.7e-109 366.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EPE35332.1 - 8.3e-43 146.5 0.0 1.2e-42 146.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EPE35332.1 - 0.029 14.4 0.0 0.1 12.7 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EPE35332.1 - 0.055 12.8 0.0 0.77 9.1 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain dCMP_cyt_deam_1 PF00383.23 EPE35333.1 - 2.5e-28 97.9 0.5 3.6e-28 97.4 0.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EPE35333.1 - 2.2e-10 40.4 0.0 4.8e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 EPE35333.1 - 2.6e-05 24.8 0.0 6.6e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 EPE35333.1 - 0.0028 17.3 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 EPE35333.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain NmrA PF05368.13 EPE35334.1 - 9.5e-17 61.3 0.0 1.2e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE35334.1 - 0.0014 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DUF2505 PF10698.9 EPE35334.1 - 0.11 12.6 0.3 0.33 11.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) His_biosynth PF00977.21 EPE35335.1 - 2.5e-48 164.5 1.0 1.3e-47 162.2 1.0 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EPE35335.1 - 8.3e-23 81.1 0.0 1.4e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EPE35335.1 - 1.5e-10 41.2 0.0 5.4e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EPE35335.1 - 5.2e-06 26.2 0.0 1.4e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 EPE35335.1 - 0.0018 18.1 0.0 0.012 15.4 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EPE35335.1 - 0.065 13.0 0.4 0.3 10.9 0.0 2.2 3 0 0 3 3 3 0 DJ-1/PfpI family Dus PF01207.17 EPE35335.1 - 0.1 11.7 0.0 0.4 9.7 0.0 1.8 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) PhyH PF05721.13 EPE35336.1 - 1.9e-24 87.1 0.0 2.6e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) NUDIX PF00293.28 EPE35337.1 - 9.2e-08 32.2 0.1 1.7e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain CFEM PF05730.11 EPE35337.1 - 0.0031 17.6 2.4 0.0078 16.3 2.4 1.6 1 0 0 1 1 1 1 CFEM domain NAD_binding_10 PF13460.6 EPE35338.1 - 0.00058 19.8 0.0 0.00067 19.6 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE35338.1 - 0.0024 17.4 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE35338.1 - 0.0029 16.6 0.1 0.0043 16.1 0.1 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EPE35338.1 - 0.034 14.0 0.3 0.29 11.0 0.3 2.0 1 1 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 EPE35338.1 - 0.048 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Uds1 PF15456.6 EPE35339.1 - 1.7e-33 115.6 4.9 3.9e-33 114.4 4.9 1.7 1 0 0 1 1 1 1 Up-regulated During Septation Stathmin PF00836.19 EPE35339.1 - 0.033 14.2 1.1 0.092 12.7 0.3 2.3 2 0 0 2 2 2 0 Stathmin family APG6_N PF17675.1 EPE35339.1 - 0.13 12.8 0.4 0.28 11.7 0.4 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Peptidase_M1 PF01433.20 EPE35340.1 - 3.3e-44 151.1 0.9 4.7e-44 150.6 0.9 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EPE35340.1 - 7.2e-40 135.6 0.0 1.4e-39 134.7 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EPE35340.1 - 2.8e-27 96.1 0.0 5.3e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 EPE35340.1 - 0.06 13.0 0.1 0.46 10.1 0.1 2.1 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 EPE35340.1 - 0.34 11.3 3.0 8 6.9 2.7 2.8 2 1 0 2 2 2 0 M61 glycyl aminopeptidase Catalase PF00199.19 EPE35343.1 - 4.4e-33 114.9 0.0 5.8e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Catalase zf-C3HC4 PF00097.25 EPE35344.1 - 1.7e-06 27.8 8.5 3.1e-06 27.0 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE35344.1 - 6.3e-06 26.1 3.5 6.3e-06 26.1 3.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EPE35344.1 - 1.1e-05 25.5 6.1 6.8e-05 22.9 6.7 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EPE35344.1 - 1.3e-05 24.9 6.5 4.6e-05 23.2 3.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE35344.1 - 2.4e-05 24.2 5.3 4.8e-05 23.2 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EPE35344.1 - 3e-05 23.8 7.0 6.8e-05 22.6 7.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE35344.1 - 3.2e-05 24.2 9.0 0.00023 21.4 9.4 2.0 1 1 1 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EPE35344.1 - 0.098 12.5 9.9 0.93 9.4 10.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 TerY_C PF15616.6 EPE35344.1 - 0.21 11.7 0.4 0.51 10.5 0.4 1.6 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_10 PF16685.5 EPE35344.1 - 0.65 10.2 2.8 1.5 9.0 2.8 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EPE35344.1 - 3.4 8.0 7.3 11 6.4 7.3 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain UCH PF00443.29 EPE35345.1 - 6.2e-45 153.7 0.0 1.3e-44 152.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPE35345.1 - 3.3e-07 30.2 0.1 0.0074 15.9 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ERG4_ERG24 PF01222.17 EPE35346.1 - 1.5e-137 458.9 22.4 1.7e-137 458.7 22.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Transp_cyt_pur PF02133.15 EPE35347.1 - 4e-96 322.5 43.2 4.7e-96 322.2 43.2 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FeoB_C PF07664.12 EPE35347.1 - 0.068 12.9 0.0 0.068 12.9 0.0 3.2 4 0 0 4 4 4 0 Ferrous iron transport protein B C terminus DUF1440 PF07274.12 EPE35347.1 - 0.068 13.5 2.6 0.12 12.7 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) DIOX_N PF14226.6 EPE35348.1 - 8e-29 100.8 0.0 1.4e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPE35348.1 - 2.6e-17 63.2 0.0 4.5e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 EPE35349.1 - 1e-18 67.4 0.2 1.9e-18 66.5 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE35349.1 - 0.00019 21.5 6.3 0.00035 20.6 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_76 PF03663.14 EPE35350.1 - 1.7e-145 485.2 15.8 2e-145 484.9 15.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EPE35350.1 - 0.21 10.7 11.4 4.2 6.4 5.8 2.9 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 Glyco_hydro_17 PF00332.18 EPE35351.1 - 9.1e-07 28.8 1.2 1.5e-06 28.1 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Dynamin_N PF00350.23 EPE35352.1 - 6.5e-20 71.9 0.0 1.2e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EPE35352.1 - 2.2e-12 46.8 0.2 4.6e-09 35.9 0.1 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EPE35352.1 - 7.6e-07 29.2 0.1 3.7e-06 27.0 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPE35352.1 - 0.0049 16.4 0.0 0.76 9.3 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Roc PF08477.13 EPE35352.1 - 0.04 14.2 0.0 0.39 10.9 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CRM1_repeat_2 PF18784.1 EPE35352.1 - 0.099 12.3 0.1 0.28 10.8 0.1 1.7 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 AAA_27 PF13514.6 EPE35352.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain SpoVG PF04026.12 EPE35352.1 - 0.11 12.7 0.0 0.75 10.0 0.0 2.4 3 0 0 3 3 3 0 SpoVG MFS_2 PF13347.6 EPE35353.1 - 1.7e-09 36.8 13.1 1.7e-09 36.8 13.1 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 EPE35353.1 - 2.6e-07 29.9 30.8 2.6e-07 29.9 30.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 EPE35354.1 - 6.3e-07 29.4 34.4 0.00017 21.6 9.0 2.8 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPE35356.1 - 1.4e-08 34.0 39.7 1.4e-08 34.0 39.7 2.9 2 2 0 2 2 2 1 Major Facilitator Superfamily RCR PF12273.8 EPE35357.1 - 4.3e-10 40.3 3.0 6.6e-10 39.7 3.0 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM51 PF15345.6 EPE35357.1 - 2.8e-05 24.1 0.0 3.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Herpes_gE PF02480.16 EPE35357.1 - 0.00033 19.5 0.0 0.00041 19.2 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Hum_adeno_E3A PF05393.11 EPE35357.1 - 0.0013 18.7 0.1 0.0017 18.3 0.1 1.3 1 0 0 1 1 1 1 Human adenovirus early E3A glycoprotein DUF2207 PF09972.9 EPE35357.1 - 0.0017 17.2 0.0 0.0019 17.1 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) GRP PF07172.11 EPE35357.1 - 0.0041 17.8 0.4 0.011 16.4 0.4 1.7 1 1 0 1 1 1 1 Glycine rich protein family EphA2_TM PF14575.6 EPE35357.1 - 0.0098 16.8 0.0 0.015 16.2 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain SCIMP PF15050.6 EPE35357.1 - 0.026 15.0 0.0 0.035 14.6 0.0 1.2 1 0 0 1 1 1 0 SCIMP protein DUF4381 PF14316.6 EPE35357.1 - 0.035 14.3 2.1 0.035 14.3 2.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) OSTbeta PF15048.6 EPE35357.1 - 0.059 13.5 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein ASFV_J13L PF05568.11 EPE35357.1 - 0.063 13.0 0.1 0.094 12.5 0.1 1.3 1 1 0 1 1 1 0 African swine fever virus J13L protein Amnionless PF14828.6 EPE35357.1 - 0.077 11.8 0.0 0.077 11.8 0.0 1.0 1 0 0 1 1 1 0 Amnionless Stevor PF17410.2 EPE35357.1 - 0.1 12.1 0.6 0.12 11.9 0.6 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TMEM190 PF15431.6 EPE35357.1 - 0.1 12.7 0.2 0.13 12.4 0.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 190 Myc_target_1 PF15179.6 EPE35357.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 Myc target protein 1 Rhabdo_glycop PF00974.18 EPE35357.1 - 0.12 10.8 0.2 0.16 10.4 0.2 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein RTA1 PF04479.13 EPE35358.1 - 1.3e-70 237.2 10.4 1.8e-70 236.8 10.4 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4190 PF13828.6 EPE35358.1 - 5.9 6.7 10.5 0.15 11.8 1.0 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4190) GET2 PF08690.10 EPE35359.1 - 3e-33 115.8 0.0 2.7e-32 112.7 0.0 2.2 1 1 0 1 1 1 1 GET complex subunit GET2 ADH_N PF08240.12 EPE35360.1 - 2.1e-21 75.8 7.8 6.8e-19 67.8 1.7 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE35360.1 - 2.1e-16 60.1 0.0 3.8e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EPE35360.1 - 7.2e-13 48.5 0.0 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EPE35360.1 - 1.7e-07 32.4 0.0 2.8e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 EPE35360.1 - 0.0079 15.5 0.5 0.013 14.8 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 EPE35360.1 - 0.025 15.0 0.0 0.061 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EPE35360.1 - 0.044 14.0 0.0 0.074 13.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_8 PF13450.6 EPE35360.1 - 0.094 13.0 0.2 0.22 11.8 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Staph_opine_DH PF10100.9 EPE35360.1 - 0.19 10.4 0.0 0.3 9.7 0.0 1.3 1 0 0 1 1 1 0 Staphylopine dehydrogenase S10_plectin PF03501.15 EPE35361.1 - 3.1e-41 139.3 0.1 5e-41 138.7 0.1 1.3 1 0 0 1 1 1 1 Plectin/S10 domain Glyco_hydro_43 PF04616.14 EPE35361.1 - 3.2e-21 75.9 1.4 3.7e-20 72.4 1.4 2.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Sde2_N_Ubi PF13019.6 EPE35362.1 - 1.9e-67 226.2 2.6 3.1e-67 225.5 2.6 1.3 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain LacI PF00356.21 EPE35362.1 - 0.34 10.8 1.1 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DUF2407 PF10302.9 EPE35362.1 - 0.44 11.1 2.7 12 6.5 0.1 2.6 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain Peptidase_M20 PF01546.28 EPE35363.1 - 6.4e-23 81.5 0.0 1.2e-22 80.7 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EPE35363.1 - 6.3e-06 26.1 0.0 1.7e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain B12D PF06522.11 EPE35364.1 - 0.00013 21.7 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.22 EPE35365.1 - 4.5e-16 58.4 0.0 8e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPE35365.1 - 0.00027 21.0 0.0 0.00037 20.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EPE35365.1 - 0.0096 15.5 0.0 0.018 14.7 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EPE35365.1 - 0.054 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 Sec16_C PF12931.7 EPE35366.1 - 2.1e-10 40.8 0.2 1.8e-09 37.7 0.1 2.4 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 EPE35366.1 - 3.8e-08 33.2 2.5 3.8e-08 33.2 2.5 4.3 3 1 2 5 5 5 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 EPE35366.1 - 2.3e-06 28.2 3.1 0.016 16.1 0.1 5.4 6 0 0 6 6 6 1 WD domain, G-beta repeat DUF1365 PF07103.11 EPE35367.1 - 1.3e-47 162.5 0.0 2.1e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) adh_short PF00106.25 EPE35368.1 - 1.4e-17 63.8 0.0 6.9e-15 55.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE35368.1 - 2.8e-12 46.7 0.0 3.6e-10 39.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE35368.1 - 2.2e-05 24.4 0.0 3.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF2863 PF11062.8 EPE35369.1 - 0.0029 16.1 0.0 0.0039 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2863) HLH PF00010.26 EPE35370.1 - 3.8e-07 30.0 0.0 1.3e-06 28.2 0.0 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain YL1 PF05764.13 EPE35370.1 - 0.22 11.6 12.4 0.33 11.0 12.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein ORC6 PF05460.13 EPE35370.1 - 7.6 5.7 12.9 13 5.0 12.9 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) IMS PF00817.20 EPE35371.1 - 1.2e-24 87.0 0.0 2.2e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EPE35371.1 - 1.2e-13 51.7 0.1 3.9e-13 50.1 0.1 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EPE35371.1 - 0.001 19.3 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Cupin_2 PF07883.11 EPE35373.1 - 2.9e-16 58.9 0.1 2.9e-16 58.9 0.1 1.6 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 EPE35373.1 - 1.4e-05 25.0 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EPE35373.1 - 1.5e-05 24.7 0.0 1.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 EPE35373.1 - 0.00011 22.4 0.1 0.00023 21.4 0.0 1.6 1 1 0 1 1 1 1 ARD/ARD' family Cupin_3 PF05899.12 EPE35373.1 - 0.0018 18.0 0.1 0.0042 16.7 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF861) EutQ PF06249.12 EPE35373.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Cupin_6 PF12852.7 EPE35373.1 - 0.02 14.6 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Cupin MarB PF13999.6 EPE35373.1 - 0.078 12.8 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 MarB protein JmjC PF02373.22 EPE35373.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase CtaG_Cox11 PF04442.14 EPE35374.1 - 1.3e-59 200.6 0.0 2.3e-59 199.8 0.0 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 cIII PF08134.11 EPE35376.1 - 0.086 12.6 2.1 1 9.2 0.1 2.5 2 0 0 2 2 2 0 cIII protein family UPF0547 PF10571.9 EPE35376.1 - 0.41 10.8 2.3 0.44 10.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn_ribbon_recom PF13408.6 EPE35376.1 - 1 9.9 3.7 16 6.1 0.6 2.6 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain PLDc_2 PF13091.6 EPE35377.1 - 1.3e-16 60.7 0.2 1.4e-09 38.0 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.8 EPE35377.1 - 0.046 12.9 0.0 1.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB PLDc PF00614.22 EPE35377.1 - 0.09 13.0 2.2 7.4 6.9 0.1 2.9 3 0 0 3 3 3 0 Phospholipase D Active site motif Peptidase_M6 PF05547.11 EPE35378.1 - 3.1e-08 32.5 0.3 0.00028 19.4 2.7 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 Ank PF00023.30 EPE35379.1 - 4.5e-13 49.0 5.7 0.0018 18.7 0.1 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 EPE35379.1 - 2.4e-12 47.3 0.9 1.5e-06 28.7 0.1 4.3 4 1 2 6 6 6 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE35379.1 - 2.7e-11 43.5 2.0 0.00055 20.2 0.1 5.0 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPE35379.1 - 3.2e-08 34.0 1.6 0.1 13.2 0.0 6.2 5 1 2 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE35379.1 - 6.1e-07 29.3 2.9 0.69 10.7 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Fer4_22 PF17179.4 EPE35379.1 - 3.5 8.5 7.2 3.2 8.7 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain bZIP_2 PF07716.15 EPE35380.1 - 1.4e-06 28.2 19.4 4.6e-06 26.6 19.4 2.0 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EPE35380.1 - 6.6e-06 26.1 18.7 1.5e-05 25.0 18.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor eIF3_subunit PF08597.10 EPE35380.1 - 0.046 13.6 7.8 0.09 12.7 7.8 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Plasmodium_Vir PF05795.11 EPE35380.1 - 0.16 11.3 1.1 0.3 10.5 1.1 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3450 PF11932.8 EPE35380.1 - 0.23 10.8 10.7 0.46 9.8 10.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_Maf PF03131.17 EPE35380.1 - 0.25 11.9 21.5 0.048 14.2 17.7 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor UPF0242 PF06785.11 EPE35380.1 - 0.69 10.0 10.0 1.4 9.0 10.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MAP17 PF15807.5 EPE35380.1 - 7.3 6.8 8.0 26 5.1 0.0 2.5 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 NmrA PF05368.13 EPE35381.1 - 8.3e-18 64.8 0.0 1e-17 64.5 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE35381.1 - 1.9e-10 40.9 0.0 3.1e-10 40.2 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE35381.1 - 0.00096 18.7 0.0 0.0026 17.3 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.13 EPE35383.1 - 1e-35 123.5 0.0 1.4e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EPE35383.1 - 1.7e-12 46.9 0.0 2.7e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EPE35383.1 - 0.0002 20.4 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EPE35383.1 - 0.038 13.5 0.0 0.57 9.6 0.0 2.3 1 1 0 1 1 1 0 Prolyl oligopeptidase family Stevor PF17410.2 EPE35383.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame BAAT_C PF08840.11 EPE35383.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal SKG6 PF08693.10 EPE35385.1 - 0.00011 21.6 0.2 0.00027 20.3 0.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.11 EPE35385.1 - 0.00052 20.5 7.3 0.00052 20.5 7.3 2.4 3 0 0 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Glycophorin_A PF01102.18 EPE35385.1 - 0.00072 19.8 0.2 0.0012 19.0 0.2 1.3 1 0 0 1 1 1 1 Glycophorin A TMEM154 PF15102.6 EPE35385.1 - 0.0041 17.0 0.5 0.0076 16.2 0.5 1.3 1 0 0 1 1 1 1 TMEM154 protein family stn_TNFRSF12A PF12191.8 EPE35385.1 - 0.013 15.7 0.4 0.039 14.2 0.1 1.8 1 1 1 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SSP160 PF06933.11 EPE35385.1 - 0.014 13.6 10.7 0.019 13.2 10.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BatD PF13584.6 EPE35385.1 - 0.014 14.2 0.1 0.019 13.8 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance Mid2 PF04478.12 EPE35385.1 - 0.02 14.7 0.1 0.038 13.8 0.1 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor PTP_tm PF18861.1 EPE35385.1 - 0.085 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J RIFIN PF02009.16 EPE35385.1 - 0.14 12.0 0.0 0.19 11.6 0.0 1.1 1 0 0 1 1 1 0 Rifin Phage_Coat_B PF05356.11 EPE35385.1 - 0.15 11.9 0.3 0.36 10.8 0.3 1.6 1 0 0 1 1 1 0 Phage Coat protein B Adeno_E3_CR2 PF02439.15 EPE35385.1 - 0.19 11.5 0.1 0.34 10.7 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 EPE35385.1 - 0.34 10.8 0.9 0.55 10.2 0.1 1.6 2 0 0 2 2 2 0 Syndecan domain dCMP_cyt_deam_1 PF00383.23 EPE35386.1 - 3.5e-24 84.6 0.1 4.6e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EPE35386.1 - 1.2e-20 73.6 0.0 1.5e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EPE35386.1 - 7.1e-05 22.9 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 EPE35386.1 - 0.00061 19.9 0.0 0.00088 19.4 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 EPE35386.1 - 0.0031 17.6 0.0 0.0042 17.2 0.0 1.3 1 0 0 1 1 1 1 APOBEC2 APOBEC_N PF08210.11 EPE35386.1 - 0.0039 17.1 0.0 0.0055 16.6 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC3 PF18771.1 EPE35386.1 - 0.011 15.8 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 Bd3614-deam PF14439.6 EPE35386.1 - 0.026 14.6 3.4 0.053 13.6 0.3 2.4 2 1 0 3 3 3 0 Bd3614-like deaminase NAD2 PF18782.1 EPE35386.1 - 0.037 14.2 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC4_like PF18774.1 EPE35386.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase NADH_u_ox_C PF12853.7 EPE35387.1 - 2e-27 95.0 0.0 3e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.9 EPE35387.1 - 2.5e-26 92.2 0.0 4.2e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Swi3 PF07962.12 EPE35388.1 - 2.8e-31 107.4 0.9 4.2e-31 106.8 0.9 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DSHCT PF08148.12 EPE35389.1 - 7.3e-51 172.1 0.2 1.8e-50 170.8 0.2 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EPE35389.1 - 1.3e-41 141.6 0.1 9.6e-41 138.8 0.1 2.2 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 EPE35389.1 - 4.2e-23 82.6 0.0 6.6e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EPE35389.1 - 5.4e-19 68.6 0.0 4.5e-18 65.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE35389.1 - 3.4e-07 30.6 0.0 1.6e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE35389.1 - 1.6e-05 24.9 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4471 PF14740.6 EPE35389.1 - 0.0078 15.5 0.2 0.015 14.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) AAA_22 PF13401.6 EPE35389.1 - 0.13 12.5 0.0 0.44 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain CitT PF12431.8 EPE35390.1 - 0.00013 22.3 2.8 3.7 8.0 0.0 5.5 5 1 0 5 5 5 1 Transcriptional regulator L_biotic_typeA PF04604.13 EPE35390.1 - 0.00045 20.0 3.7 0.78 9.6 0.0 4.9 5 1 1 6 6 6 1 Type-A lantibiotic ATP-cone PF03477.16 EPE35390.1 - 0.011 16.2 22.3 0.52 10.9 6.7 4.6 1 1 2 3 3 3 0 ATP cone domain DUF433 PF04255.14 EPE35390.1 - 0.27 11.1 4.8 50 3.9 0.2 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF433) SHS2_FTSA PF02491.20 EPE35390.1 - 0.7 10.3 17.9 10 6.6 0.3 5.5 2 1 4 6 6 6 0 SHS2 domain inserted in FTSA PSD5 PF07637.11 EPE35390.1 - 1.7 9.0 12.8 1.5e+02 2.9 0.0 6.4 5 2 2 7 7 7 0 Protein of unknown function (DUF1595) CBP_BcsR PF10945.8 EPE35390.1 - 4.8 6.8 5.4 33 4.1 0.2 3.2 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsR SNAPc19 PF15497.6 EPE35390.1 - 4.8 7.7 21.6 16 6.0 1.2 4.4 1 1 4 5 5 5 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 SRR1 PF07985.12 EPE35391.1 - 7e-07 29.2 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 SRR1 OAD_gamma PF04277.13 EPE35392.1 - 0.14 12.8 0.0 0.48 11.0 0.0 1.9 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Podoplanin PF05808.11 EPE35392.1 - 1.1 9.4 3.5 1.1 9.4 0.2 2.6 2 0 0 2 2 2 0 Podoplanin AAT PF03417.16 EPE35393.1 - 1.2e-33 116.7 0.0 1.6e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Rpr2 PF04032.16 EPE35394.1 - 0.077 13.3 0.5 0.19 12.0 0.1 1.8 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Lactamase_B PF00753.27 EPE35395.1 - 5.4e-26 91.8 0.1 8.9e-26 91.1 0.1 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EPE35395.1 - 2.6e-05 23.8 0.0 3.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FMO-like PF00743.19 EPE35396.1 - 8.7e-12 44.2 0.1 9.9e-10 37.4 0.0 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EPE35396.1 - 1.5e-11 44.3 0.0 4.7e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE35396.1 - 3.8e-07 29.6 0.0 9e-05 21.8 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE35396.1 - 4e-07 29.6 0.0 4.6e-05 22.8 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPE35396.1 - 1.6e-05 24.3 0.0 0.11 11.6 0.0 3.5 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EPE35396.1 - 0.001 19.1 0.1 0.013 15.4 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 EPE35396.1 - 0.18 11.0 0.0 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Thi4 family TFIIA PF03153.13 EPE35398.1 - 1.9 8.4 21.2 2.1 8.2 21.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EPE35398.1 - 2.5 6.3 16.1 3.1 6.0 16.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyoxalase PF00903.25 EPE35399.1 - 0.02 15.1 0.0 0.071 13.3 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AAA_12 PF13087.6 EPE35401.1 - 4.8e-38 130.8 0.0 8e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EPE35401.1 - 7.9e-26 91.4 0.0 2.5e-25 89.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPE35401.1 - 2.8e-08 33.7 0.1 1.3e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EPE35401.1 - 6.9e-08 32.5 0.0 0.00019 21.3 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EPE35401.1 - 1.6e-07 31.8 2.2 2.2e-06 28.1 0.8 2.8 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EPE35401.1 - 6.5e-05 22.3 0.6 0.034 13.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EPE35401.1 - 0.0027 17.2 0.1 0.0057 16.1 0.1 1.4 1 0 0 1 1 1 1 PhoH-like protein ResIII PF04851.15 EPE35401.1 - 0.0051 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EPE35401.1 - 0.0071 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 EPE35401.1 - 0.028 14.0 0.1 0.086 12.3 0.1 2.0 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EPE35401.1 - 0.048 13.0 0.2 1.1 8.5 0.0 2.3 1 1 0 2 2 2 0 UvrD-like helicase C-terminal domain RuvB_N PF05496.12 EPE35401.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Helicase_RecD PF05127.14 EPE35401.1 - 0.18 11.6 0.0 0.51 10.2 0.0 1.7 2 0 0 2 2 2 0 Helicase WD40 PF00400.32 EPE35402.1 - 8.5e-10 39.1 1.8 1.1 10.3 0.0 7.3 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE35402.1 - 0.016 15.5 0.0 17 5.8 0.0 3.6 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIF_alpha PF05793.12 EPE35402.1 - 0.25 9.9 6.8 0.51 8.9 6.5 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 EPE35402.1 - 0.65 8.2 5.6 0.98 7.6 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein TSC22 PF01166.18 EPE35405.1 - 0.078 13.3 8.1 0.24 11.7 0.6 2.8 2 1 0 2 2 2 0 TSC-22/dip/bun family Fez1 PF06818.15 EPE35405.1 - 0.88 10.0 13.4 1.6 9.1 13.4 1.5 1 0 0 1 1 1 0 Fez1 GIT_CC PF16559.5 EPE35405.1 - 0.89 9.5 6.8 0.95 9.4 1.7 3.0 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-F_leu_zip PF10473.9 EPE35405.1 - 1.4 8.9 17.2 0.1 12.6 4.2 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Apc15p PF05841.11 EPE35405.1 - 1.8 9.4 8.2 0.2 12.5 2.0 2.2 1 1 1 2 2 2 0 Apc15p protein PKcGMP_CC PF16808.5 EPE35405.1 - 3.8 7.4 9.4 0.49 10.3 0.4 2.9 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DivIC PF04977.15 EPE35405.1 - 4.9 7.0 8.0 5.2 6.9 1.9 3.0 2 1 1 3 3 3 0 Septum formation initiator ATG16 PF08614.11 EPE35405.1 - 9.7 6.4 21.4 35 4.5 21.4 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 EPE35406.1 - 0.012 15.7 0.2 0.012 15.7 0.2 6.4 5 1 0 6 6 6 0 bZIP transcription factor FERM_M PF00373.18 EPE35406.1 - 0.046 14.1 2.6 9.9 6.6 0.1 3.6 3 0 0 3 3 3 0 FERM central domain DUF2461 PF09365.10 EPE35406.1 - 0.63 10.0 5.4 3.5 7.5 5.4 2.3 1 1 0 1 1 1 0 Conserved hypothetical protein (DUF2461) EF-hand_14 PF17959.1 EPE35406.1 - 4.5 7.7 5.0 1.2 9.5 0.6 2.4 2 0 0 2 2 2 0 EF-hand domain Shugoshin_N PF07558.11 EPE35406.1 - 4.9 7.1 6.9 1.3 8.9 0.6 3.3 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region MFS_2 PF13347.6 EPE35407.1 - 9.8e-10 37.5 4.4 9.8e-10 37.5 4.4 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein Na_H_Exchanger PF00999.21 EPE35409.1 - 3.7e-73 246.5 38.7 4.5e-73 246.2 38.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NiFe_hyd_3_EhaA PF17367.2 EPE35409.1 - 0.65 10.2 18.3 0.32 11.1 2.5 4.1 2 1 1 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A PIG-X PF08320.12 EPE35410.1 - 3.3e-63 213.4 0.0 4.5e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 SARAF PF06682.12 EPE35411.1 - 2.9e-91 306.6 7.4 7.1e-91 305.3 7.4 1.5 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis COX8 PF02285.15 EPE35411.1 - 0.0016 18.3 3.0 0.0069 16.2 1.1 2.4 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIII BRE1 PF08647.11 EPE35412.1 - 8.1e-28 96.4 8.8 8.1e-28 96.4 8.8 7.4 7 1 2 9 9 6 2 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 EPE35412.1 - 4.8e-08 32.7 7.2 7.2e-08 32.2 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE35412.1 - 1.7e-07 31.2 5.8 3.1e-07 30.3 5.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EPE35412.1 - 1.9e-07 30.8 11.0 3.4e-07 30.0 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE35412.1 - 2.3e-07 30.5 9.3 3.9e-07 29.8 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE35412.1 - 2e-06 28.0 8.0 3.3e-06 27.3 8.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EPE35412.1 - 4.2e-06 26.6 10.4 7.1e-06 25.9 10.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EPE35412.1 - 5e-06 26.3 6.8 8.4e-06 25.6 6.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EPE35412.1 - 0.008 16.3 6.0 0.016 15.4 6.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING HALZ PF02183.18 EPE35412.1 - 0.01 16.0 1.0 0.01 16.0 1.0 6.8 7 0 0 7 7 7 0 Homeobox associated leucine zipper Bap31_Bap29_C PF18035.1 EPE35412.1 - 0.011 15.7 2.7 0.011 15.7 2.7 5.8 5 2 1 6 6 5 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF2501 PF10696.9 EPE35412.1 - 0.012 15.9 0.0 0.052 13.8 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2501) DUF1272 PF06906.11 EPE35412.1 - 0.02 14.9 6.6 0.052 13.6 6.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 EPE35412.1 - 0.053 13.3 8.4 0.28 11.0 8.6 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 EPE35412.1 - 0.09 12.7 1.9 0.18 11.7 1.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2_jaz PF12171.8 EPE35412.1 - 0.12 12.7 7.8 3.9 7.9 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-RING_10 PF16685.5 EPE35412.1 - 0.78 9.9 4.9 2.1 8.5 4.9 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 FYVE PF01363.21 EPE35412.1 - 1.2 9.3 11.0 13 6.0 11.2 2.3 1 1 1 2 2 2 0 FYVE zinc finger zf-rbx1 PF12678.7 EPE35412.1 - 4.2 7.7 10.3 4.3 7.7 7.5 2.4 2 1 0 2 2 1 0 RING-H2 zinc finger domain GAS PF13851.6 EPE35412.1 - 5.6 6.3 73.3 0.11 11.9 17.5 6.3 4 2 0 5 5 5 0 Growth-arrest specific micro-tubule binding Myb_DNA-bind_7 PF15963.5 EPE35413.1 - 5.5e-23 80.7 1.8 5.5e-23 80.7 1.8 2.5 2 1 1 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EPE35413.1 - 5.3e-05 23.3 0.1 0.0001 22.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain NPV_P10 PF05531.12 EPE35413.1 - 0.096 13.2 0.5 0.23 12.0 0.5 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Annexin PF00191.20 EPE35413.1 - 0.1 12.7 0.1 7 6.8 0.0 2.7 2 0 0 2 2 2 0 Annexin Myb_DNA-bind_6 PF13921.6 EPE35413.1 - 0.11 12.7 0.1 0.26 11.6 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Aldo_ket_red PF00248.21 EPE35414.1 - 7e-45 153.5 0.1 1.6e-42 145.7 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family P3A PF08727.11 EPE35414.1 - 0.0028 17.0 0.5 0.56 9.6 0.0 2.7 1 1 1 2 2 2 2 Poliovirus 3A protein like Dev_Cell_Death PF10539.9 EPE35414.1 - 0.017 15.0 0.0 0.07 13.0 0.0 1.9 2 0 0 2 2 2 0 Development and cell death domain GFA PF04828.14 EPE35415.1 - 0.0083 16.4 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Glyco_hydro_1 PF00232.18 EPE35416.1 - 1.3e-147 491.9 0.0 1.5e-147 491.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Mod_r PF07200.13 EPE35417.1 - 4.7e-06 26.8 3.8 4.7e-06 26.8 3.8 2.9 1 1 2 3 3 3 1 Modifier of rudimentary (Mod(r)) protein CorA PF01544.18 EPE35417.1 - 0.003 16.9 4.1 0.003 16.9 4.1 2.4 2 0 0 2 2 1 1 CorA-like Mg2+ transporter protein Vac_Fusion PF02346.16 EPE35417.1 - 0.012 15.3 7.0 0.65 9.7 0.1 3.4 2 1 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Cnn_1N PF07989.11 EPE35417.1 - 0.049 13.8 0.2 0.049 13.8 0.2 4.2 2 2 3 5 5 5 0 Centrosomin N-terminal motif 1 THOC7 PF05615.13 EPE35417.1 - 0.052 13.8 27.3 0.83 9.9 11.0 4.2 1 1 3 4 4 4 0 Tho complex subunit 7 FliD_N PF02465.18 EPE35417.1 - 0.081 13.6 1.7 6 7.6 0.0 2.7 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Rimk_N PF18030.1 EPE35417.1 - 0.09 13.2 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 RimK PreATP-grasp domain DUF1664 PF07889.12 EPE35417.1 - 0.095 12.7 0.2 0.095 12.7 0.2 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) YabA PF06156.13 EPE35417.1 - 0.44 11.2 19.8 0.18 12.4 0.5 4.0 2 1 1 4 4 3 0 Initiation control protein YabA Prefoldin PF02996.17 EPE35417.1 - 0.49 10.3 13.4 4 7.4 0.1 3.9 2 1 1 3 3 3 0 Prefoldin subunit Sec34 PF04136.15 EPE35417.1 - 0.71 9.7 9.0 4.9 7.0 0.1 3.2 1 1 3 4 4 4 0 Sec34-like family Prefoldin_2 PF01920.20 EPE35417.1 - 0.85 9.6 12.8 0.45 10.5 0.2 3.5 3 2 0 3 3 3 0 Prefoldin subunit FapA PF03961.13 EPE35417.1 - 1.2 7.6 9.8 0.027 13.1 1.6 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A APG6_N PF17675.1 EPE35417.1 - 1.9 9.0 36.1 0.19 12.3 6.6 3.3 1 1 2 3 3 3 0 Apg6 coiled-coil region FlaC_arch PF05377.11 EPE35417.1 - 2.5 8.6 4.8 22 5.6 0.1 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ERM PF00769.19 EPE35417.1 - 4.9 6.9 33.8 1.5 8.6 1.2 2.6 1 1 1 2 2 2 0 Ezrin/radixin/moesin family HALZ PF02183.18 EPE35417.1 - 7.1 6.9 17.9 16 5.8 0.1 4.7 4 1 0 4 4 3 0 Homeobox associated leucine zipper HRDC PF00570.23 EPE35418.1 - 0.19 11.7 0.0 0.34 10.9 0.0 1.3 1 0 0 1 1 1 0 HRDC domain DivIC PF04977.15 EPE35419.1 - 0.015 15.0 15.3 0.25 11.1 0.1 3.3 3 0 0 3 3 3 0 Septum formation initiator TolA_bind_tri PF16331.5 EPE35419.1 - 0.017 15.2 7.1 5.1 7.3 2.2 3.4 3 0 0 3 3 3 0 TolA binding protein trimerisation H-kinase_dim PF02895.14 EPE35419.1 - 0.06 13.7 2.0 1.4 9.3 0.1 2.9 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain PRKG1_interact PF15898.5 EPE35419.1 - 0.07 14.0 17.0 0.15 13.0 0.1 3.5 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain TMF_TATA_bd PF12325.8 EPE35419.1 - 0.08 13.2 12.0 1.6 8.9 3.1 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding PikAIV_N PF18605.1 EPE35419.1 - 0.091 12.4 3.9 1.6 8.4 0.1 2.5 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain HMMR_N PF15905.5 EPE35419.1 - 0.65 9.4 20.9 0.22 11.0 16.3 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Cep57_CLD_2 PF14197.6 EPE35419.1 - 1.7 8.8 14.1 0.25 11.5 0.4 3.5 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 TPR_MLP1_2 PF07926.12 EPE35419.1 - 1.9 8.6 29.8 0.15 12.1 11.7 3.0 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 EPE35419.1 - 2.3 8.9 20.6 6.3 7.5 9.7 3.6 2 1 2 4 4 4 0 Initiation control protein YabA NRBF2 PF08961.10 EPE35419.1 - 3 7.4 16.8 2.1 7.9 5.1 2.6 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator Atg14 PF10186.9 EPE35419.1 - 4.1 6.4 18.1 32 3.5 18.2 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 bZIP_1 PF00170.21 EPE35419.1 - 4.8 7.3 16.5 3.5 7.8 0.4 3.5 3 0 0 3 3 3 0 bZIP transcription factor Golgin_A5 PF09787.9 EPE35419.1 - 5.7 6.3 20.1 4.3 6.7 2.2 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 FmiP_Thoc5 PF09766.9 EPE35420.1 - 0.49 9.6 6.5 0.79 8.9 6.5 1.3 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 PCRF PF03462.18 EPE35420.1 - 0.91 9.3 4.2 0.98 9.2 3.4 1.4 1 1 0 1 1 1 0 PCRF domain Glyco_hydro_16 PF00722.21 EPE35421.1 - 4.2e-09 36.1 0.0 9.5e-09 35.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Y_phosphatase3 PF13350.6 EPE35422.1 - 1.3e-37 130.0 0.0 1.8e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EPE35422.1 - 0.0013 18.4 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 EPE35422.1 - 0.017 14.1 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DSPc PF00782.20 EPE35422.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain adh_short_C2 PF13561.6 EPE35423.1 - 1.7e-62 211.1 0.5 1.9e-62 210.9 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE35423.1 - 1.3e-54 184.7 0.2 1.5e-54 184.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE35423.1 - 2.5e-10 40.6 0.3 3.7e-10 40.0 0.3 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EPE35423.1 - 0.0007 19.0 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 EPE35423.1 - 0.0097 15.4 1.0 0.046 13.2 0.2 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EPE35423.1 - 0.018 15.3 0.3 0.033 14.5 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EPE35423.1 - 0.11 12.6 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.8 EPE35423.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.18 EPE35423.1 - 0.23 11.3 0.7 0.51 10.2 0.3 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 EPE35424.1 - 2.9e-31 108.4 0.9 1.8e-21 76.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE35424.1 - 5e-24 85.2 0.5 7.9e-22 78.0 0.5 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE35424.1 - 5.4e-05 23.2 0.1 9.4e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EPE35424.1 - 0.00032 20.2 0.0 0.0012 18.3 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EPE35424.1 - 0.037 13.5 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EPE35424.1 - 0.079 12.3 0.1 0.15 11.3 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DSBA PF01323.20 EPE35425.1 - 5.4e-13 49.1 0.0 6.3e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain NAD_binding_10 PF13460.6 EPE35426.1 - 3.3e-26 92.3 0.1 4.1e-26 92.0 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EPE35426.1 - 0.079 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 EPE35426.1 - 0.2 10.8 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Prominin PF05478.11 EPE35429.1 - 0.39 8.6 2.0 0.46 8.4 2.0 1.0 1 0 0 1 1 1 0 Prominin Host_attach PF10116.9 EPE35429.1 - 0.61 10.7 7.5 0.65 10.6 6.5 1.5 1 1 0 1 1 1 0 Protein required for attachment to host cells zf-CCCH_6 PF18585.1 EPE35429.1 - 1.9 8.4 5.0 4.9 7.1 1.4 2.2 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 AAA_11 PF13086.6 EPE35429.1 - 2.8 7.7 9.5 3.3 7.4 9.5 1.1 1 0 0 1 1 1 0 AAA domain Sigma70_ECF PF07638.11 EPE35429.1 - 8.6 6.2 14.3 0.64 9.9 7.6 2.0 1 1 1 2 2 2 0 ECF sigma factor CAF1 PF04857.20 EPE35430.1 - 3.6e-24 85.5 0.0 2.8e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease NDUF_B12 PF08122.12 EPE35431.1 - 2.1e-26 91.7 1.5 2.8e-26 91.3 1.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family HATPase_c PF02518.26 EPE35432.1 - 1.8e-19 70.3 0.0 4.8e-19 68.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPE35432.1 - 8.4e-19 67.8 0.0 3.5e-18 65.8 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EPE35432.1 - 8.8e-13 48.1 0.0 3.1e-12 46.3 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain YmgB PF10798.8 EPE35432.1 - 0.59 10.0 2.0 23 4.9 0.0 3.2 3 0 0 3 3 3 0 Biofilm development protein YmgB/AriR Sugar_tr PF00083.24 EPE35433.1 - 1.1e-106 357.5 18.3 1.2e-106 357.3 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE35433.1 - 2.1e-22 79.6 34.5 5.9e-15 55.0 13.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Beta-lactamase PF00144.24 EPE35434.1 - 2.9e-45 155.0 0.0 7.7e-45 153.6 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase F-box-like PF12937.7 EPE35435.1 - 9.3e-05 22.2 0.3 9.3e-05 22.2 0.3 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EPE35435.1 - 0.0065 16.3 0.2 0.018 14.9 0.2 1.8 1 0 0 1 1 1 1 F-box domain DUF1496 PF07383.12 EPE35435.1 - 0.096 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1496) HypA PF01155.19 EPE35435.1 - 0.14 12.2 0.3 0.68 10.0 0.2 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EPE35435.1 - 0.33 11.0 4.9 0.6 10.2 0.6 2.8 3 0 0 3 3 3 0 Double zinc ribbon zinc_ribbon_5 PF13719.6 EPE35435.1 - 3.5 7.5 5.9 6.1 6.7 3.1 2.7 2 1 1 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 EPE35435.1 - 7.8 6.5 8.5 3.3 7.7 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Pkinase PF00069.25 EPE35436.1 - 8e-09 35.2 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EPE35436.1 - 0.00051 19.5 0.0 0.00081 18.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPE35436.1 - 0.00091 19.2 0.0 0.15 12.0 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EPE35436.1 - 0.0024 17.2 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 EPE35437.1 - 5.7e-10 39.6 19.4 0.086 13.8 0.2 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Mg_trans_NIPA PF05653.14 EPE35438.1 - 8.8e-65 218.7 13.1 3.8e-62 210.1 8.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EPE35438.1 - 0.00025 21.3 24.8 0.00074 19.7 2.0 3.7 3 1 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 EPE35438.1 - 0.002 17.7 0.2 0.002 17.7 0.2 2.2 1 1 0 2 2 2 1 Solute carrier family 35 DUF2101 PF09874.9 EPE35438.1 - 0.14 11.9 2.2 0.16 11.7 1.1 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2101) DUF1461 PF07314.11 EPE35438.1 - 0.41 10.5 5.8 0.64 9.9 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) F-box PF00646.33 EPE35440.1 - 0.00019 21.2 0.1 0.00066 19.5 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPE35440.1 - 0.00027 20.8 0.3 0.00096 19.0 0.0 2.0 2 0 0 2 2 2 1 F-box-like zinc_ribbon_4 PF13717.6 EPE35440.1 - 0.0042 17.0 0.0 0.0098 15.8 0.0 1.6 1 0 0 1 1 1 1 zinc-ribbon domain Hydrolase_6 PF13344.6 EPE35441.1 - 2.4e-10 40.4 0.0 5.7e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase His_biosynth PF00977.21 EPE35442.1 - 6.3e-36 124.0 0.0 8.4e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribosomal_S11 PF00411.19 EPE35442.1 - 0.2 12.0 0.0 0.69 10.3 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein S11 Ribul_P_3_epim PF00834.19 EPE35442.1 - 0.21 10.9 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.6 EPE35443.1 - 6.2e-12 46.0 14.5 1.2e-11 45.0 14.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) Phage_holin_3_6 PF07332.11 EPE35446.1 - 0.24 11.4 5.1 0.24 11.4 0.2 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III XPC-binding PF09280.11 EPE35447.1 - 3.1e-25 87.7 12.0 5.3e-25 86.9 12.0 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 EPE35447.1 - 3.7e-22 77.8 4.6 2e-13 49.9 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 EPE35447.1 - 1.8e-19 69.3 0.4 3e-19 68.5 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EPE35447.1 - 3.6e-07 29.9 0.5 5.9e-07 29.2 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EPE35447.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SOG2 PF10428.9 EPE35447.1 - 0.037 13.2 1.1 0.041 13.1 1.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CDC45 PF02724.14 EPE35448.1 - 0.071 11.4 5.3 0.13 10.5 5.3 1.5 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EPE35448.1 - 3.2 7.0 18.2 5.9 6.1 18.2 1.4 1 0 0 1 1 1 0 NOA36 protein eIF-6 PF01912.18 EPE35449.1 - 1.4e-80 269.3 1.7 2e-80 268.9 1.7 1.2 1 0 0 1 1 1 1 eIF-6 family Swi5 PF07061.11 EPE35450.1 - 3.6e-28 97.4 0.3 9.1e-28 96.2 0.3 1.7 1 0 0 1 1 1 1 Swi5 DUF4075 PF13294.6 EPE35450.1 - 0.021 15.0 0.2 0.29 11.3 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4075) DUF1192 PF06698.11 EPE35450.1 - 0.072 13.2 1.7 0.21 11.6 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF1752 PF08550.10 EPE35450.1 - 0.3 11.0 0.2 0.74 9.7 0.1 1.7 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1752) LOR PF04525.12 EPE35451.1 - 1.4e-27 96.5 0.1 1.8e-27 96.2 0.1 1.0 1 0 0 1 1 1 1 LURP-one-related GFA PF04828.14 EPE35452.1 - 1.7e-20 73.1 1.1 1.8e-20 73.0 0.4 1.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 EPE35452.1 - 0.17 12.1 4.5 4.5 7.5 0.2 2.4 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like SVS_QK PF10578.9 EPE35452.1 - 0.17 12.5 0.3 0.42 11.3 0.3 1.5 1 0 0 1 1 1 0 Seminal vesicle protein repeat Rpr2 PF04032.16 EPE35452.1 - 0.31 11.3 2.6 0.84 10.0 0.0 2.1 1 1 2 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Glyco_hydro_35 PF01301.19 EPE35453.1 - 5.2e-79 266.1 8.5 8.1e-79 265.5 8.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 EPE35453.1 - 5.4e-56 189.3 3.4 1.1e-55 188.2 3.4 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 EPE35453.1 - 7.1e-54 181.2 9.0 4.1e-30 104.7 0.0 4.4 3 1 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 EPE35453.1 - 8.1e-24 83.0 0.3 2.8e-23 81.3 0.3 2.0 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 EPE35453.1 - 0.0001 21.8 0.4 0.00074 19.0 0.7 2.2 1 1 1 2 2 2 1 Beta-galactosidase Cellulase PF00150.18 EPE35453.1 - 0.0028 17.1 0.1 0.022 14.2 0.0 2.3 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Crystall_2 PF09076.10 EPE35453.1 - 0.26 11.2 2.2 0.89 9.5 0.3 2.6 2 0 0 2 2 2 0 Beta/Gamma crystallin Aminotran_3 PF00202.21 EPE35454.1 - 7.9e-121 403.5 0.0 9e-121 403.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EPE35454.1 - 0.004 16.4 0.0 0.006 15.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II AT_hook PF02178.19 EPE35455.1 - 0.066 13.1 0.2 0.066 13.1 0.2 2.9 3 0 0 3 3 3 0 AT hook motif SET PF00856.28 EPE35457.1 - 4.1e-21 76.1 1.6 2e-20 73.9 0.1 3.0 2 1 0 2 2 2 1 SET domain SRI PF08236.11 EPE35457.1 - 6.1e-19 68.0 12.3 1.8e-18 66.5 12.3 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 EPE35457.1 - 4.1e-13 49.1 12.3 4.1e-13 49.1 12.3 2.3 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 EPE35457.1 - 0.00034 20.6 0.1 0.0014 18.6 0.1 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.26 EPE35457.1 - 0.013 15.6 0.9 0.03 14.4 0.9 1.7 1 0 0 1 1 1 0 WW domain TERB2 PF15101.6 EPE35457.1 - 9.4 6.2 7.3 2 8.4 2.7 2.1 1 1 1 2 2 2 0 Telomere-associated protein TERB2 DUF2431 PF10354.9 EPE35458.1 - 1.9e-54 184.4 0.0 2.4e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) ThiF PF00899.21 EPE35459.1 - 3.3e-27 95.4 0.0 4.4e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family Zn_clus PF00172.18 EPE35460.1 - 1.2e-09 38.1 5.9 2.6e-09 37.0 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE35460.1 - 0.0013 17.6 1.3 0.043 12.6 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Glyco_hydro_43 PF04616.14 EPE35461.1 - 5.6e-18 65.3 0.1 3.9e-17 62.5 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Methyltransf_23 PF13489.6 EPE35462.1 - 6.1e-17 61.9 0.0 9.3e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE35462.1 - 3.3e-10 40.5 0.0 1.4e-09 38.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE35462.1 - 9.4e-08 32.6 0.0 2.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE35462.1 - 7.9e-06 25.7 0.0 0.0001 22.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE35462.1 - 2.9e-05 24.7 0.0 0.00014 22.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EPE35462.1 - 0.0054 16.1 0.0 0.009 15.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EPE35462.1 - 0.008 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EPE35462.1 - 0.0092 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 EPE35462.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EPE35462.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.18 EPE35462.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EPE35462.1 - 0.17 11.2 0.0 0.36 10.1 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF2218 PF09981.9 EPE35464.1 - 0.072 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) TFIIA PF03153.13 EPE35465.1 - 9.1e-86 289.4 47.1 1.3e-84 285.6 47.1 2.0 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.16 EPE35466.1 - 5.2e-33 114.4 25.1 5.2e-33 114.4 25.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4381 PF14316.6 EPE35466.1 - 0.22 11.7 2.6 3.1 8.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) ANAPC4_WD40 PF12894.7 EPE35467.1 - 6.5e-18 64.8 4.8 1e-06 28.9 0.2 4.5 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPE35467.1 - 1.2e-16 60.8 20.6 0.00064 20.5 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.11 EPE35467.1 - 5.5e-07 29.7 0.2 0.00023 21.1 0.1 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EPE35467.1 - 8.9e-07 28.2 0.1 0.00021 20.4 0.0 3.5 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Kelch_4 PF13418.6 EPE35468.1 - 4.8e-27 93.7 8.7 8.2e-09 35.3 0.0 4.8 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EPE35468.1 - 6.9e-23 80.1 3.4 0.00011 22.4 0.0 5.0 3 1 1 4 4 4 4 Kelch motif Kelch_5 PF13854.6 EPE35468.1 - 3.9e-22 77.8 8.0 6.1e-07 29.3 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EPE35468.1 - 7.6e-21 73.4 1.5 9.7e-06 25.1 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EPE35468.1 - 1.1e-17 63.3 6.0 0.00042 20.2 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 EPE35468.1 - 7.8e-17 61.1 5.7 1.4e-06 28.5 0.1 5.5 6 0 0 6 6 6 2 Galactose oxidase, central domain BTB PF00651.31 EPE35468.1 - 2.6e-10 40.5 0.0 4.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Mito_carr PF00153.27 EPE35470.1 - 3e-58 193.7 2.1 1.1e-20 73.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EPE35470.1 - 0.049 12.8 5.9 2 7.5 0.1 3.5 3 1 1 4 4 4 0 Gammaproteobacterial serine protease YtxH PF12732.7 EPE35470.1 - 0.75 10.4 3.4 5.1 7.7 0.1 3.0 3 0 0 3 3 3 0 YtxH-like protein GWT1 PF06423.12 EPE35472.1 - 5.9e-42 143.3 3.3 2.5e-41 141.3 3.8 1.8 2 0 0 2 2 2 1 GWT1 DUF4818 PF16089.5 EPE35472.1 - 0.0054 17.2 0.0 0.0054 17.2 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4818) Pkinase PF00069.25 EPE35473.1 - 2.5e-63 213.9 0.0 3.9e-63 213.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE35473.1 - 1.1e-35 123.2 0.0 3.3e-30 105.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EPE35473.1 - 1.2e-06 28.0 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EPE35473.1 - 0.00086 19.3 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EPE35473.1 - 0.013 14.5 0.1 0.021 13.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EPE35473.1 - 0.055 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EPE35473.1 - 0.2 11.3 0.0 0.42 10.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Lactamase_B_3 PF13483.6 EPE35474.1 - 1.9e-05 24.6 0.0 4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EPE35474.1 - 0.00091 18.8 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DEAD PF00270.29 EPE35475.1 - 4.6e-29 101.4 0.0 9.8e-29 100.3 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE35475.1 - 7e-24 84.3 0.0 1.3e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE35475.1 - 6.8e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SbcCD_C PF13558.6 EPE35475.1 - 0.075 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Clr5 PF14420.6 EPE35476.1 - 3.9e-19 68.6 6.1 1.1e-18 67.1 4.6 2.6 2 0 0 2 2 2 1 Clr5 domain Nif11 PF07862.11 EPE35476.1 - 0.033 14.5 0.1 0.69 10.3 0.0 3.0 2 0 0 2 2 2 0 Nif11 domain FAD-oxidase_C PF02913.19 EPE35477.1 - 2.5e-59 200.9 0.2 3.6e-59 200.4 0.2 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EPE35477.1 - 1.3e-35 122.1 0.0 3.6e-35 120.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Lipocalin_3 PF12702.7 EPE35477.1 - 0.14 12.3 0.0 0.53 10.4 0.0 1.9 2 0 0 2 2 2 0 Lipocalin-like SPRY PF00622.28 EPE35478.1 - 2e-05 24.7 0.0 3.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 SPRY domain DUF1996 PF09362.10 EPE35480.1 - 5.9e-84 281.7 0.5 8.5e-84 281.2 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TPP_enzyme_N PF02776.18 EPE35481.1 - 3.5e-28 98.4 0.1 5.9e-27 94.4 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EPE35481.1 - 7.1e-18 64.8 0.8 3.2e-17 62.7 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EPE35481.1 - 0.00058 19.6 0.0 0.0058 16.4 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Amidase PF01425.21 EPE35482.1 - 6.8e-92 308.8 0.2 3.5e-91 306.4 0.0 2.1 2 1 0 2 2 2 1 Amidase Formyl_trans_N PF00551.19 EPE35483.1 - 1.1e-37 129.6 0.1 1.3e-37 129.3 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 EPE35483.1 - 6.3e-08 32.3 0.0 1.6e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EPE35483.1 - 0.0002 21.3 0.0 0.00065 19.6 0.0 2.0 2 0 0 2 2 2 1 ACT domain DUF5483 PF17581.2 EPE35483.1 - 0.044 12.7 0.0 0.055 12.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5483) Glyco_transf_25 PF01755.17 EPE35484.1 - 4.1e-12 46.4 0.0 9.3e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF4377 PF14302.6 EPE35486.1 - 0.11 12.5 0.1 3.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4377) RCR PF12273.8 EPE35486.1 - 1.1 10.0 11.7 13 6.5 11.5 2.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red E1-E2_ATPase PF00122.20 EPE35487.1 - 3.9e-36 124.3 14.0 4.8e-31 107.7 0.6 3.9 4 1 1 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EPE35487.1 - 4.8e-26 91.6 7.3 4.8e-26 91.6 7.3 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EPE35487.1 - 3.9e-18 66.5 0.4 3.6e-14 53.6 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EPE35487.1 - 2.8e-15 55.7 0.0 9e-15 54.1 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EPE35487.1 - 9.8e-14 51.2 0.0 2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EPE35487.1 - 1.1e-05 25.3 2.8 4.6e-05 23.3 1.9 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EPE35487.1 - 0.006 17.0 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 EPE35487.1 - 0.22 11.4 4.7 0.083 12.8 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) Tautomerase_3 PF14832.6 EPE35488.1 - 5.8e-34 117.3 0.0 6.5e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme CFEM PF05730.11 EPE35489.1 - 1.7e-13 50.5 11.2 1.7e-13 50.5 11.2 1.7 2 0 0 2 2 2 1 CFEM domain MFS_1 PF07690.16 EPE35490.1 - 5.6e-34 117.6 23.9 5.6e-34 117.6 23.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE35490.1 - 2.3e-11 43.2 9.0 2.3e-11 43.2 9.0 3.2 2 2 1 4 4 4 1 Sugar (and other) transporter DUF1772 PF08592.11 EPE35491.1 - 5.7e-08 33.2 0.6 7.8e-08 32.7 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) adh_short_C2 PF13561.6 EPE35492.1 - 1.1e-35 123.3 0.9 1.8e-35 122.6 0.9 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE35492.1 - 4.3e-29 101.4 1.2 5.3e-29 101.1 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE35492.1 - 3.5e-07 30.3 1.8 2.6e-06 27.5 0.2 2.0 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EPE35492.1 - 0.042 13.0 0.1 0.072 12.2 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF917 PF06032.12 EPE35492.1 - 0.045 12.6 1.7 0.058 12.2 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF917) DEAD PF00270.29 EPE35493.1 - 1.6e-18 67.1 0.0 5.7e-18 65.3 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE35493.1 - 2.7e-08 34.1 0.0 2.5e-07 31.0 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE35493.1 - 1.4e-06 28.4 0.0 3.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 EPE35493.1 - 0.0036 17.9 0.1 0.042 14.5 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain BEN PF10523.9 EPE35493.1 - 0.17 12.1 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 BEN domain DUF3717 PF12512.8 EPE35494.1 - 0.075 12.9 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) FOXP-CC PF16159.5 EPE35495.1 - 0.097 13.3 2.9 13 6.5 0.1 3.6 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 EPE35495.1 - 0.32 11.1 3.2 0.36 11.0 1.9 1.8 1 1 0 1 1 1 0 Aberrant zinc-finger HTH_Tnp_Tc3_2 PF01498.18 EPE35500.1 - 1.1e-09 38.4 0.8 1.7e-08 34.6 0.3 2.6 2 0 0 2 2 2 1 Transposase DDE_3 PF13358.6 EPE35500.1 - 3.2e-08 33.4 0.4 9e-08 32.0 0.1 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_38 PF13936.6 EPE35500.1 - 2.9e-05 23.7 0.4 7.7e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4 PF04545.16 EPE35500.1 - 0.06 12.9 0.1 0.52 9.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_32 PF13565.6 EPE35500.1 - 0.62 10.7 10.2 2.6 8.7 0.7 3.5 2 1 1 3 3 3 0 Homeodomain-like domain SNF2_N PF00176.23 EPE35501.1 - 7.4e-22 77.5 0.0 1.8e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE35501.1 - 2.5e-09 37.4 0.0 7.3e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE35501.1 - 5.8e-08 32.9 1.4 1.1e-07 32.0 0.0 2.2 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit Nop14 PF04147.12 EPE35501.1 - 0.00092 17.6 40.3 0.0013 17.1 40.3 1.1 1 0 0 1 1 1 1 Nop14-like family DEAD PF00270.29 EPE35501.1 - 0.00093 19.0 0.0 0.0055 16.5 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase CDC45 PF02724.14 EPE35501.1 - 0.0073 14.7 33.7 0.012 14.0 33.7 1.2 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 EPE35501.1 - 0.061 12.7 49.3 0.11 11.9 49.3 1.3 1 0 0 1 1 1 0 SDA1 DDHD PF02862.17 EPE35501.1 - 0.14 12.3 3.8 0.44 10.7 3.8 1.9 1 0 0 1 1 1 0 DDHD domain Nop53 PF07767.11 EPE35501.1 - 0.71 9.2 33.6 1.3 8.3 33.6 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4614 PF15391.6 EPE35501.1 - 1 9.4 12.1 2.8 7.9 12.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Presenilin PF01080.17 EPE35501.1 - 1.2 7.8 19.2 2 7.1 19.2 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 EPE35501.1 - 3.4 6.4 16.0 5.8 5.7 16.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM76 PF16046.5 EPE35503.1 - 0.72 9.2 7.2 0.042 13.2 1.1 2.0 3 0 0 3 3 3 0 FAM76 protein DUF3849 PF12960.7 EPE35505.1 - 0.11 12.5 0.5 8.3 6.4 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3849) zf-HC5HC2H_2 PF13832.6 EPE35506.1 - 2.7e-21 75.8 1.5 2.7e-21 75.8 1.5 4.2 3 1 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EPE35506.1 - 1.1e-16 60.8 2.3 1.1e-16 60.8 2.3 4.8 4 1 0 4 4 4 2 PHD-like zinc-binding domain BAH PF01426.18 EPE35506.1 - 2.3e-16 59.7 1.2 3.4e-16 59.2 0.1 2.0 2 0 0 2 2 2 1 BAH domain PHD PF00628.29 EPE35506.1 - 5.5e-12 45.4 54.0 5e-06 26.3 8.1 6.4 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.6 EPE35506.1 - 5.6e-09 35.4 6.8 5.6e-09 35.4 6.8 5.6 6 0 0 6 6 6 1 PHD-finger Myb_DNA-binding PF00249.31 EPE35506.1 - 0.0071 16.5 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_2 PF03107.16 EPE35506.1 - 0.36 11.2 47.4 0.095 13.0 0.8 6.2 7 0 0 7 7 7 0 C1 domain C1_1 PF00130.22 EPE35506.1 - 1 9.3 51.3 0.017 15.0 4.9 5.9 6 1 1 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 EPE35506.1 - 5.6 7.0 36.8 0.52 10.3 7.0 4.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Git3 PF11710.8 EPE35507.1 - 5.9e-15 55.6 12.5 5.9e-15 55.6 12.5 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EPE35507.1 - 5.9e-09 35.9 3.1 7.2e-09 35.6 0.1 2.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 EPE35507.1 - 0.00058 19.3 7.3 0.088 12.1 7.3 2.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) FMO-like PF00743.19 EPE35508.1 - 8.8e-32 110.2 0.0 1e-13 50.6 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EPE35508.1 - 4.2e-10 39.4 0.0 9.2e-09 34.9 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE35508.1 - 5.1e-10 39.1 0.0 3.9e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPE35508.1 - 8.6e-06 25.1 0.0 0.011 14.9 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EPE35508.1 - 0.00064 19.7 0.0 0.92 9.5 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EPE35508.1 - 0.17 12.2 0.0 0.67 10.2 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain WD40 PF00400.32 EPE35509.1 - 3.3e-14 53.1 11.3 0.0095 16.8 0.1 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE35509.1 - 7.1e-06 26.2 0.0 0.25 11.7 0.0 4.0 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 EPE35510.1 - 5.9e-08 32.4 0.0 1.2e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPE35510.1 - 9.2e-05 22.0 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Autophagy_act_C PF03987.15 EPE35511.1 - 3e-13 50.1 0.2 5.9e-13 49.2 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Glyco_hydro_47 PF01532.20 EPE35513.1 - 1.1e-168 561.9 0.0 1.4e-168 561.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AA_permease PF00324.21 EPE35514.1 - 1.7e-145 485.3 37.1 2.1e-145 485.0 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE35514.1 - 1.5e-38 132.8 38.8 1.8e-38 132.5 38.8 1.1 1 0 0 1 1 1 1 Amino acid permease His_Phos_2 PF00328.22 EPE35515.1 - 9.7e-08 31.8 0.4 3e-06 26.8 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) PDGLE PF13190.6 EPE35515.1 - 0.013 15.4 0.1 0.077 12.9 0.1 2.2 2 0 0 2 2 2 0 PDGLE domain ADH_zinc_N PF00107.26 EPE35516.1 - 5e-12 45.9 0.0 1.4e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE35516.1 - 6.4e-06 26.0 0.4 4.6e-05 23.2 0.2 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EPE35516.1 - 0.042 14.9 0.0 0.097 13.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF3445 PF11927.8 EPE35519.1 - 2e-71 240.2 0.0 8.6e-71 238.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3445) Fungal_trans PF04082.18 EPE35520.1 - 3e-08 33.0 0.0 5.7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPE35521.1 - 4.3e-13 48.9 11.8 3.6e-06 27.1 2.4 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPE35521.1 - 1.1e-12 47.7 8.9 1.9e-07 31.2 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPE35521.1 - 6.4e-09 35.9 10.4 0.00041 21.0 1.5 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EPE35521.1 - 2.1e-07 30.8 8.6 0.00032 20.6 0.3 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE35521.1 - 2.8e-06 27.4 0.4 0.088 13.1 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPE35521.1 - 3.6e-05 24.0 0.8 0.013 15.8 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EPE35521.1 - 0.0056 16.4 4.8 0.41 10.4 0.7 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 EPE35521.1 - 0.032 14.7 1.0 0.078 13.5 1.0 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 EPE35521.1 - 0.074 13.4 2.3 0.18 12.1 1.4 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 EPE35521.1 - 0.27 11.7 1.9 11 6.5 0.3 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 EPE35521.1 - 0.81 10.0 3.4 17 5.7 0.1 2.4 1 1 1 2 2 2 0 LIM domain C5HCH PF17982.1 EPE35521.1 - 4.1 7.7 6.4 33 4.7 1.4 2.8 1 1 1 2 2 2 0 NSD Cys-His rich domain FMN_red PF03358.15 EPE35522.1 - 1.4e-11 44.4 0.0 1.6e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EPE35522.1 - 1.8e-06 27.8 0.0 2.2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 EPE35522.1 - 5.1e-06 26.7 0.2 0.00039 20.7 0.1 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EPE35522.1 - 0.0043 17.3 0.0 0.024 14.9 0.0 1.9 1 1 1 2 2 2 1 Flavodoxin domain WW PF00397.26 EPE35523.1 - 8.9e-11 41.7 0.3 2e-10 40.6 0.3 1.7 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 EPE35523.1 - 0.0041 16.2 0.1 0.013 14.5 0.1 1.7 2 0 0 2 2 2 1 PhoD-like phosphatase AAA_22 PF13401.6 EPE35524.1 - 2.7e-12 47.1 0.0 5.3e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EPE35524.1 - 3.1e-12 47.1 0.1 9.8e-12 45.4 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE35524.1 - 7.9e-10 39.4 0.1 1.3e-08 35.4 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.11 EPE35524.1 - 2.8e-09 36.8 0.1 4.1e-08 33.1 0.1 2.6 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 EPE35524.1 - 5.5e-08 32.9 0.0 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 EPE35524.1 - 3.8e-05 24.0 0.9 0.00014 22.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EPE35524.1 - 0.00014 21.2 0.0 0.00026 20.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain KAP_NTPase PF07693.14 EPE35524.1 - 0.00025 20.4 0.1 0.00039 19.8 0.1 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_7 PF12775.7 EPE35524.1 - 0.00037 20.1 0.1 0.00091 18.8 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 EPE35524.1 - 0.00065 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein DUF815 PF05673.13 EPE35524.1 - 0.0014 17.8 0.1 0.0037 16.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA12 PF10443.9 EPE35524.1 - 0.0031 16.3 0.0 0.0053 15.5 0.0 1.3 1 0 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 EPE35524.1 - 0.0061 16.5 0.6 0.022 14.7 0.6 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 EPE35524.1 - 0.012 14.7 0.1 0.022 13.8 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 EPE35524.1 - 0.014 15.4 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EPE35524.1 - 0.023 15.1 0.0 0.06 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 EPE35524.1 - 0.07 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 EPE35524.1 - 0.092 12.7 0.3 0.28 11.1 0.3 1.8 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_32 PF13654.6 EPE35524.1 - 0.092 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain STAC2_u1 PF16664.5 EPE35524.1 - 0.092 13.2 1.8 0.18 12.3 0.7 2.1 2 0 0 2 2 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 RuvB_N PF05496.12 EPE35524.1 - 0.12 12.2 0.1 0.4 10.4 0.0 1.9 1 1 1 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NB-ARC PF00931.22 EPE35524.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 EPE35524.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain UvrB_inter PF17757.1 EPE35524.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 UvrB interaction domain DUF3884 PF13024.6 EPE35524.1 - 0.19 11.3 0.0 0.43 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) PMM PF03332.13 EPE35525.1 - 2.6e-89 298.8 0.2 2.3e-88 295.7 0.2 1.9 1 1 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.13 EPE35525.1 - 0.024 14.2 0.0 2.4 7.6 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 EPE35525.1 - 0.15 11.8 0.0 4.7 6.9 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Aminotran_4 PF01063.19 EPE35526.1 - 3.1e-25 89.3 0.0 1.3e-24 87.3 0.0 1.8 1 1 0 1 1 1 1 Amino-transferase class IV AATase PF07247.12 EPE35527.1 - 6.2e-16 58.0 0.0 4e-10 38.9 0.0 2.4 2 1 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.20 EPE35527.1 - 5e-06 25.5 0.1 0.084 11.5 0.0 2.4 2 1 0 2 2 2 2 Condensation domain KH_7 PF17214.3 EPE35527.1 - 0.13 12.2 0.0 0.42 10.6 0.0 1.8 1 0 0 1 1 1 0 KH domain NAPRTase PF04095.16 EPE35528.1 - 9.4e-54 182.6 0.3 5.8e-28 98.1 0.9 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EPE35528.1 - 1.7e-33 115.7 0.1 3e-33 114.8 0.1 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF3464 PF11947.8 EPE35528.1 - 0.044 13.5 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Peptidase_M24 PF00557.24 EPE35528.1 - 0.099 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase family M24 WD40 PF00400.32 EPE35529.1 - 3.4e-19 68.8 26.5 1.3e-06 29.0 0.1 11.0 11 0 0 11 11 11 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE35529.1 - 0.017 15.4 0.2 6.8 7.1 0.0 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EPE35529.1 - 0.043 12.6 4.7 0.61 8.8 0.0 3.3 2 1 0 2 2 2 0 Nup133 N terminal like Abhydrolase_6 PF12697.7 EPE35530.1 - 0.0048 17.5 0.1 0.012 16.2 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EPE35530.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_1 PF00561.20 EPE35530.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EPE35530.1 - 0.52 9.2 1.7 1.2 8.0 0.3 2.2 2 1 0 2 2 2 0 Chlorophyllase enzyme ADH_zinc_N PF00107.26 EPE35531.1 - 2.4e-28 98.7 0.4 4.7e-28 97.8 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPE35531.1 - 2.9e-12 47.8 0.0 4.9e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPE35531.1 - 0.00021 21.1 0.0 0.00047 20.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 EPE35531.1 - 0.025 14.7 0.5 0.18 12.0 0.5 2.4 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Spt5-NGN PF03439.13 EPE35532.1 - 3.4e-23 81.4 0.1 5.8e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 EPE35532.1 - 3.2e-21 76.2 9.5 3.2e-21 76.2 9.5 3.6 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 EPE35532.1 - 1.3e-18 67.3 36.0 2.1e-17 63.5 19.1 4.8 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 EPE35532.1 - 1.8e-07 30.8 20.8 0.00056 19.8 0.0 5.1 5 0 0 5 5 5 2 KOW motif DUF3912 PF13051.6 EPE35532.1 - 4.1e-05 23.8 0.2 0.0015 18.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3912) Cornifin PF02389.15 EPE35532.1 - 1.3 9.2 8.8 2.7 8.2 8.8 1.5 1 0 0 1 1 1 0 Cornifin (SPRR) family DUF3506 PF12014.8 EPE35533.1 - 6.9e-60 201.1 0.0 1.2e-59 200.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 EPE35533.1 - 5.7e-06 26.1 0.3 1.1e-05 25.2 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE35533.1 - 0.00016 21.4 0.2 0.00032 20.5 0.2 1.4 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 EPE35533.1 - 0.0024 18.4 0.1 0.0049 17.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF1769 PF08588.10 EPE35534.1 - 2.4e-28 98.1 0.5 5.5e-28 96.9 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Transglut_C PF00927.22 EPE35534.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain WD40 PF00400.32 EPE35535.1 - 2.2e-11 44.1 8.5 0.00014 22.6 0.1 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat CTP_transf_like PF01467.26 EPE35536.1 - 3.8e-06 27.1 0.1 1.2e-05 25.5 0.1 1.8 1 1 0 1 1 1 1 Cytidylyltransferase-like PRANC PF09372.10 EPE35537.1 - 0.04 14.2 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 PRANC domain adh_short_C2 PF13561.6 EPE35538.1 - 3.1e-47 161.1 0.1 3.7e-47 160.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE35538.1 - 6.9e-30 104.0 0.2 9.5e-30 103.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE35538.1 - 6.8e-06 26.1 0.1 9.3e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Jnk-SapK_ap_N PF09744.9 EPE35539.1 - 0.0061 16.8 10.8 2.2 8.5 0.0 2.7 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 Cob_adeno_trans PF01923.18 EPE35539.1 - 0.023 14.9 4.5 0.025 14.7 2.5 2.0 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Spc7 PF08317.11 EPE35539.1 - 0.056 12.3 11.1 0.04 12.8 7.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein SKA2 PF16740.5 EPE35539.1 - 0.092 12.5 5.2 0.059 13.2 1.1 2.6 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Filament PF00038.21 EPE35539.1 - 0.13 11.8 12.6 0.36 10.4 7.5 2.3 2 0 0 2 2 2 0 Intermediate filament protein XhlA PF10779.9 EPE35539.1 - 0.68 10.2 6.9 1.1 9.5 3.4 2.6 3 0 0 3 3 3 0 Haemolysin XhlA DivIC PF04977.15 EPE35539.1 - 1.6 8.6 8.4 32 4.4 0.0 2.7 2 0 0 2 2 2 0 Septum formation initiator DUF724 PF05266.14 EPE35539.1 - 2.2 8.1 10.4 1.3 8.8 6.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF724) DUF1640 PF07798.11 EPE35539.1 - 2.9 7.9 9.6 16 5.5 4.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) ZapB PF06005.12 EPE35539.1 - 6.2 7.3 16.5 6.5 7.3 8.7 3.0 3 0 0 3 3 3 0 Cell division protein ZapB DUF1748 PF08520.10 EPE35540.1 - 2e-31 107.7 0.0 8e-31 105.8 0.0 1.8 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1748) PK PF00224.21 EPE35541.1 - 4.8e-170 565.0 9.2 6e-170 564.7 9.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EPE35541.1 - 1.8e-35 121.7 0.0 1.1e-34 119.1 0.0 2.4 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EPE35541.1 - 0.00022 20.4 0.6 0.0011 18.2 0.3 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EPE35541.1 - 0.03 13.3 0.1 0.24 10.4 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Abhydrolase_6 PF12697.7 EPE35542.1 - 1.4e-05 25.8 0.7 0.00018 22.2 0.7 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE35542.1 - 0.0012 18.6 2.8 0.041 13.5 1.7 3.0 2 2 0 2 2 2 1 alpha/beta hydrolase fold Syntaxin-6_N PF09177.11 EPE35542.1 - 0.053 14.1 0.8 0.11 13.1 0.8 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal SIP PF04954.13 EPE35542.1 - 0.25 11.9 1.6 0.34 11.4 0.0 1.9 3 0 0 3 3 3 0 Siderophore-interacting protein Kelch_4 PF13418.6 EPE35543.1 - 5.8e-14 51.8 0.5 8.1e-05 22.6 0.0 5.2 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EPE35543.1 - 2.9e-12 46.3 0.3 0.00063 19.7 0.0 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 EPE35543.1 - 1.4e-11 44.4 2.8 7.7e-08 32.4 0.0 4.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EPE35543.1 - 7e-11 41.5 0.3 0.091 12.4 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 EPE35543.1 - 8.4e-09 35.4 5.1 0.18 12.2 0.0 5.5 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 EPE35543.1 - 1.2e-06 28.3 2.4 0.0043 17.0 0.0 4.6 4 1 0 4 4 4 1 Kelch motif BTB PF00651.31 EPE35543.1 - 0.02 15.1 0.0 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain DUF4719 PF15843.5 EPE35543.1 - 1.5 8.9 5.4 1.4 9.0 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) Nop PF01798.18 EPE35544.1 - 1.6e-72 243.7 0.0 2.2e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EPE35544.1 - 5.5e-46 156.4 2.3 5.5e-46 156.4 2.3 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain HAT PF02184.16 EPE35545.1 - 8.1e-28 96.1 62.6 2.3e-14 53.0 2.1 13.7 14 0 0 14 14 14 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 EPE35545.1 - 3.6e-21 75.4 1.9 1.7e-05 25.2 0.0 8.0 7 1 2 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 EPE35545.1 - 3.8e-21 74.0 29.9 0.0022 18.6 0.1 11.4 8 4 4 12 12 12 6 Tetratricopeptide repeat Suf PF05843.14 EPE35545.1 - 3.3e-15 56.8 20.7 0.00034 20.7 0.7 6.1 3 1 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 EPE35545.1 - 7.5e-11 41.6 3.9 0.034 14.5 0.0 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPE35545.1 - 2.4e-09 36.6 24.0 0.52 10.6 0.0 10.1 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPE35545.1 - 3.8e-09 36.0 10.5 0.44 10.9 0.0 7.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EPE35545.1 - 9.7e-06 26.1 11.1 0.78 10.4 0.0 7.3 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 EPE35545.1 - 1.8e-05 24.8 3.0 24 5.2 0.0 6.2 4 1 0 5 5 5 0 Tetratricopeptide repeat NRDE-2 PF08424.10 EPE35545.1 - 0.00053 19.2 28.2 0.25 10.5 0.1 7.0 4 3 2 6 6 6 4 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 EPE35545.1 - 0.00058 20.3 22.5 32 5.4 0.1 9.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_15 PF13429.6 EPE35545.1 - 0.00088 18.6 19.6 0.088 12.0 1.9 6.3 4 2 2 6 6 6 1 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EPE35545.1 - 0.0016 18.5 27.1 0.024 14.7 1.3 7.6 6 2 2 8 8 8 2 U3 small nucleolar RNA-associated protein 6 TPR_1 PF00515.28 EPE35545.1 - 0.016 15.0 6.4 58 3.7 0.0 6.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE35545.1 - 0.049 13.9 7.2 2.1 8.7 0.0 4.8 5 1 1 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 ECSIT PF06239.11 EPE35545.1 - 0.29 10.2 5.1 0.24 10.5 0.5 2.4 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_12 PF13424.6 EPE35545.1 - 3 8.2 26.2 3.5 8.0 0.1 8.2 9 2 1 10 10 10 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 EPE35547.1 - 1.2e-05 25.4 9.6 0.004 17.5 1.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE35547.1 - 0.0041 17.8 7.4 0.13 13.2 0.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger MTP18 PF10558.9 EPE35547.1 - 0.039 13.9 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) zf-TRAF PF02176.18 EPE35547.1 - 1.4 9.7 4.9 3.7 8.3 1.0 2.3 1 1 2 3 3 3 0 TRAF-type zinc finger zf-met PF12874.7 EPE35547.1 - 2 8.9 13.2 0.46 11.0 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EPE35547.1 - 5 7.7 12.9 0.1 13.0 1.7 3.0 3 0 0 3 3 3 0 Zinc-finger double domain XFP_N PF09364.10 EPE35548.1 - 3.8e-139 463.5 0.5 5.5e-101 338.0 0.1 2.2 1 1 1 2 2 2 2 XFP N-terminal domain XFP_C PF09363.10 EPE35548.1 - 2.1e-79 265.7 0.0 4e-79 264.8 0.0 1.5 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 EPE35548.1 - 1.9e-76 255.7 0.0 2.8e-76 255.1 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 EPE35548.1 - 0.0033 17.2 0.1 0.0078 16.0 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Acetate_kinase PF00871.17 EPE35549.1 - 1.2e-88 297.5 0.0 1.4e-88 297.2 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family GST_N_3 PF13417.6 EPE35550.1 - 1.8e-18 66.7 0.0 3.9e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPE35550.1 - 4.4e-13 49.3 0.0 1.3e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EPE35550.1 - 6.8e-08 32.7 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 EPE35550.1 - 0.00071 20.1 0.0 0.0014 19.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EPE35550.1 - 0.00093 19.4 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 EPE35550.1 - 0.00097 19.1 0.2 0.0025 17.8 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EPE35550.1 - 0.0091 16.7 0.0 0.023 15.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 EPE35550.1 - 0.089 13.0 0.0 0.089 13.0 0.0 2.3 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain PUL PF08324.11 EPE35552.1 - 2.6e-67 227.0 3.1 3.6e-67 226.5 3.1 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EPE35552.1 - 1.6e-44 150.7 0.6 3.4e-44 149.7 0.3 1.7 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EPE35552.1 - 6.8e-32 109.0 14.3 7.3e-05 23.5 0.0 8.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 EPE35552.1 - 0.058 12.0 0.1 4.2 5.9 0.0 2.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Pyridox_ox_2 PF12900.7 EPE35552.1 - 0.094 12.7 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Peptidase_S41 PF03572.18 EPE35553.1 - 3.4e-08 33.2 0.0 1e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 HET PF06985.11 EPE35554.1 - 1.2e-25 90.6 0.2 2.5e-25 89.5 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FMO-like PF00743.19 EPE35555.1 - 6.6e-32 110.6 0.0 1.9e-17 62.9 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EPE35555.1 - 8.1e-17 61.4 0.0 6.4e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPE35555.1 - 4.8e-13 49.0 0.0 1.5e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE35555.1 - 4.2e-09 36.5 0.0 1.8e-08 34.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE35555.1 - 1.1e-07 31.7 2.0 2.5e-05 24.1 1.7 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EPE35555.1 - 6e-07 29.6 1.1 0.00024 21.1 0.3 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EPE35555.1 - 3.1e-05 24.1 0.6 0.13 12.4 0.3 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.6 EPE35555.1 - 4.9e-05 22.6 0.1 0.015 14.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EPE35555.1 - 0.00011 22.7 1.4 0.0022 18.5 0.5 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EPE35555.1 - 0.0005 19.5 0.0 0.0016 17.8 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EPE35555.1 - 0.00095 18.0 0.8 0.0015 17.3 0.8 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EPE35555.1 - 0.0015 17.7 0.3 0.0024 17.0 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EPE35555.1 - 0.0029 16.9 0.1 0.0052 16.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EPE35555.1 - 0.0045 16.3 1.0 0.023 13.9 0.4 2.1 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EPE35555.1 - 0.014 14.7 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 EPE35555.1 - 0.015 15.0 0.0 0.093 12.4 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 EPE35555.1 - 0.021 14.4 0.9 0.03 13.9 0.1 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain OprF PF05736.11 EPE35555.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 OprF membrane domain NAD_binding_2 PF03446.15 EPE35555.1 - 0.074 13.2 0.1 0.19 11.9 0.0 1.7 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.22 EPE35555.1 - 0.11 11.6 1.0 0.19 10.7 1.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EPE35555.1 - 0.12 12.8 0.0 3.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EPE35555.1 - 0.13 11.5 1.8 0.18 11.1 0.5 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EPE35555.1 - 0.19 10.5 1.4 0.29 10.0 1.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.18 EPE35555.1 - 0.25 11.2 2.2 0.21 11.5 0.7 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.22 EPE35556.1 - 3.6e-51 174.4 0.0 4.5e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxidored_FMN PF00724.20 EPE35557.1 - 7.8e-65 219.4 0.0 8.8e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MARCKS PF02063.17 EPE35558.1 - 0.013 15.5 70.2 0.21 11.5 24.8 2.3 2 0 0 2 2 2 0 MARCKS family NAD_binding_10 PF13460.6 EPE35559.1 - 3.6e-08 33.5 0.2 6.9e-08 32.6 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPE35559.1 - 9.1e-08 31.9 0.1 1.4e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EPE35559.1 - 1.3e-05 25.5 0.1 2.1e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EPE35559.1 - 4.3e-05 24.0 0.1 9.5e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EPE35559.1 - 0.0083 15.3 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein DXP_reductoisom PF02670.16 EPE35559.1 - 0.0084 16.8 0.0 0.014 16.1 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_Gly3P_dh_N PF01210.23 EPE35559.1 - 0.019 15.0 0.1 0.057 13.4 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3Beta_HSD PF01073.19 EPE35559.1 - 0.05 12.6 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 EPE35559.1 - 0.085 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CbiA PF01656.23 EPE35560.1 - 5.9e-05 23.1 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_12 PF13087.6 EPE35560.1 - 0.00018 21.2 0.0 0.00038 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPE35560.1 - 0.0017 18.1 0.1 0.003 17.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EPE35560.1 - 0.0028 17.3 0.1 0.0064 16.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPE35560.1 - 0.0031 17.9 0.3 0.009 16.4 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EPE35560.1 - 0.022 14.5 0.1 0.061 13.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain UvrD-helicase PF00580.21 EPE35560.1 - 0.052 13.1 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_28 PF13521.6 EPE35560.1 - 0.061 13.6 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EPE35560.1 - 0.061 13.8 0.1 0.21 12.1 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 EPE35560.1 - 0.064 13.0 0.2 0.96 9.2 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EPE35560.1 - 0.073 13.4 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Herpes_UL79 PF03049.14 EPE35560.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 UL79 family T2SSE PF00437.20 EPE35560.1 - 0.1 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 EPE35560.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PIF1 PF05970.14 EPE35560.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase NACHT PF05729.12 EPE35560.1 - 0.13 12.1 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 NACHT domain BNIP2 PF12496.8 EPE35561.1 - 0.13 12.7 1.7 3 8.3 0.1 2.7 3 1 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 HET PF06985.11 EPE35562.1 - 3.2e-26 92.4 0.0 6.8e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pec_lyase_C PF00544.19 EPE35563.1 - 7.3e-41 140.1 4.0 1e-40 139.6 4.0 1.3 1 0 0 1 1 1 1 Pectate lyase Sugarporin_N PF11471.8 EPE35563.1 - 0.17 11.9 1.2 0.32 11.0 0.5 1.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Glyco_hydro_11 PF00457.17 EPE35564.1 - 4.3e-62 208.9 18.3 5e-62 208.7 18.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF4179 PF13786.6 EPE35564.1 - 0.062 13.8 0.3 0.2 12.1 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) Phage_lysis PF03245.13 EPE35565.1 - 0.037 14.2 3.8 0.14 12.3 0.1 2.9 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein SPRY PF00622.28 EPE35566.1 - 0.16 12.1 0.1 26 5.0 0.0 2.5 1 1 1 2 2 2 0 SPRY domain Fib_alpha PF08702.10 EPE35566.1 - 0.77 9.9 15.4 7.2 6.8 0.1 4.7 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family DUF4094 PF13334.6 EPE35566.1 - 2.1 8.8 7.2 8.9 6.8 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) Baculo_PEP_C PF04513.12 EPE35566.1 - 2.4 8.2 11.4 0.39 10.8 0.6 3.6 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TSC22 PF01166.18 EPE35566.1 - 3.5 8.0 5.0 9.3 6.7 0.2 3.6 3 0 0 3 3 3 0 TSC-22/dip/bun family GAS PF13851.6 EPE35566.1 - 3.9 6.8 16.5 6 6.2 6.1 3.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 EPE35566.1 - 4.9 7.0 18.5 0.47 10.3 1.6 4.3 4 0 0 4 4 4 0 Septum formation initiator SlyX PF04102.12 EPE35566.1 - 6.4 7.5 17.0 11 6.7 0.2 4.7 4 0 0 4 4 4 0 SlyX Lebercilin PF15619.6 EPE35566.1 - 7.1 6.2 19.1 14 5.2 1.0 4.9 5 0 0 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 EPE35566.1 - 8.6 5.1 18.5 2.1 7.2 8.9 3.4 2 2 2 4 4 4 0 Spc7 kinetochore protein DUF724 PF05266.14 EPE35566.1 - 8.7 6.1 11.1 4.2 7.1 2.5 3.2 3 2 0 3 3 3 0 Protein of unknown function (DUF724) Thioredoxin_12 PF18400.1 EPE35567.1 - 0.0095 15.8 0.7 0.019 14.8 0.5 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Bcr-Abl_Oligo PF09036.10 EPE35567.1 - 0.091 12.8 3.4 5.9 7.0 0.1 3.6 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Fez1 PF06818.15 EPE35568.1 - 1.7 9.1 23.4 0.025 15.0 8.7 2.6 1 1 2 3 3 3 0 Fez1 UPF0242 PF06785.11 EPE35568.1 - 4.6 7.3 20.0 0.51 10.4 11.1 2.9 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus MFS_1 PF07690.16 EPE35570.1 - 2.2e-41 142.0 40.9 2.2e-41 142.0 40.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE35570.1 - 1.8e-09 37.0 8.2 1.8e-09 37.0 8.2 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EPE35570.1 - 3.5e-08 32.4 1.6 5.4e-08 31.7 1.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.18 EPE35571.1 - 0.00021 21.4 9.0 0.00041 20.4 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE35571.1 - 0.0049 15.9 0.7 0.012 14.6 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain APH PF01636.23 EPE35572.1 - 1e-08 35.4 0.0 2.7e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family ketoacyl-synt PF00109.26 EPE35573.1 - 1.3e-64 218.3 0.0 3.6e-64 216.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EPE35573.1 - 5.6e-60 203.1 0.1 6.4e-58 196.3 0.0 2.5 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EPE35573.1 - 3.6e-48 164.7 0.0 6.5e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE35573.1 - 1.5e-36 125.0 0.3 4.6e-36 123.4 0.3 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EPE35573.1 - 3.8e-14 53.4 0.2 1.9e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 EPE35573.1 - 9e-11 42.0 0.5 2.5e-10 40.5 0.5 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 EPE35573.1 - 2e-10 40.4 0.0 4.3e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EPE35573.1 - 5.4e-08 33.3 0.1 1.9e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ketoacyl-synt PF00109.26 EPE35574.1 - 9.9e-70 235.0 0.1 1.7e-69 234.2 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EPE35574.1 - 3.3e-63 212.8 0.0 1.6e-62 210.6 0.0 2.3 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 EPE35574.1 - 4.2e-46 157.6 0.0 7.6e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EPE35574.1 - 2.6e-45 155.3 0.1 4.1e-45 154.7 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPE35574.1 - 2.6e-38 130.7 0.0 2e-37 127.8 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 EPE35574.1 - 4.5e-17 63.3 0.0 1.6e-16 61.6 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPE35574.1 - 9.7e-17 61.2 0.0 2.9e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EPE35574.1 - 4.9e-15 56.0 0.0 1.5e-14 54.4 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EPE35574.1 - 1.3e-11 44.3 0.0 1.3e-11 44.3 0.0 3.1 5 0 0 5 5 5 1 short chain dehydrogenase PP-binding PF00550.25 EPE35574.1 - 1.4e-07 31.8 0.0 3.8e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EPE35574.1 - 4e-06 26.4 0.3 1.3e-05 24.7 0.2 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain SAT PF16073.5 EPE35574.1 - 0.057 13.2 0.6 0.32 10.7 0.7 2.2 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis ThiF PF00899.21 EPE35574.1 - 0.099 12.0 0.2 0.55 9.5 0.1 2.2 2 0 0 2 2 2 0 ThiF family TPR_2 PF07719.17 EPE35576.1 - 2e-08 33.7 2.6 0.00032 20.6 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPE35576.1 - 4.9e-07 29.4 0.5 0.00058 19.9 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EPE35576.1 - 7.1e-07 28.8 0.8 0.033 14.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPE35576.1 - 4.3e-05 23.9 0.1 0.00077 19.9 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EPE35576.1 - 0.0016 18.7 0.7 2.7 8.3 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EPE35576.1 - 0.07 13.2 0.0 6.9 6.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPE35576.1 - 0.094 13.6 0.2 5 8.2 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EPE35576.1 - 0.1 13.2 0.1 3.4 8.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat APH PF01636.23 EPE35578.1 - 1.1e-07 32.1 0.0 4.4e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE35578.1 - 4.3e-05 23.2 0.0 6.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EPE35578.1 - 0.08 12.5 0.0 5.5 6.5 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 EPE35578.1 - 0.17 11.3 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain LysM PF01476.20 EPE35580.1 - 5.3e-05 23.2 0.2 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 2 LysM domain zf-C2H2_4 PF13894.6 EPE35581.1 - 0.073 14.0 0.4 0.073 14.0 0.4 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger Ivy PF08816.11 EPE35581.1 - 0.094 12.9 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Inhibitor of vertebrate lysozyme (Ivy) T5orf172 PF10544.9 EPE35582.1 - 3e-24 85.5 1.0 7.3e-24 84.3 0.1 2.1 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 EPE35582.1 - 1.1e-23 83.7 0.2 2.3e-23 82.7 0.2 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 PGAP1 PF07819.13 EPE35584.1 - 1.2e-05 25.2 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EPE35584.1 - 0.00076 19.1 0.1 0.0013 18.3 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) HeLo PF14479.6 EPE35584.1 - 0.001 19.0 0.1 0.0023 17.8 0.1 1.6 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF726 PF05277.12 EPE35584.1 - 0.02 13.8 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.7 EPE35584.1 - 0.063 13.9 0.0 0.19 12.3 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.8 EPE35584.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF829 PF05705.14 EPE35584.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Pkinase PF00069.25 EPE35585.1 - 5e-23 81.8 0.0 9e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE35585.1 - 4e-19 68.9 0.0 7.2e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.6 EPE35585.1 - 1.9e-11 44.1 7.3 0.0001 22.5 0.1 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EPE35585.1 - 8.4e-11 41.4 0.5 0.0038 17.1 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Pkinase_fungal PF17667.1 EPE35585.1 - 2.6e-05 23.2 0.0 5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EPE35585.1 - 0.0004 20.4 0.1 0.001 19.1 0.1 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EPE35585.1 - 0.00041 19.8 0.0 0.00097 18.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_7 PF13176.6 EPE35585.1 - 0.00071 19.4 0.2 19 5.6 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 EPE35585.1 - 0.025 14.8 0.4 1.1e+02 3.3 0.1 4.2 4 0 0 4 4 4 0 PPR repeat Cas9_a PF18470.1 EPE35585.1 - 0.048 13.2 0.2 0.087 12.4 0.2 1.4 1 0 0 1 1 1 0 Cas9 alpha-helical lobe domain TPR_2 PF07719.17 EPE35585.1 - 0.062 13.4 0.9 10 6.5 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EPE35585.1 - 0.073 13.3 1.0 69 4.0 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 EPE35585.1 - 0.16 12.7 0.1 0.67 10.7 0.1 2.0 1 0 0 1 1 1 0 Sel1 repeat HRXXH PF13933.6 EPE35587.1 - 1.4e-08 34.6 2.2 2.8e-08 33.6 2.2 1.4 1 1 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 EPE35587.1 - 0.00017 22.1 2.8 0.00022 21.8 1.1 2.0 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase DUF1961 PF09224.11 EPE35587.1 - 0.015 14.6 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1961) Peptidase_M35 PF02102.15 EPE35587.1 - 0.03 13.2 4.4 0.82 8.5 0.8 2.6 2 1 0 2 2 2 0 Deuterolysin metalloprotease (M35) family GP46 PF07409.12 EPE35587.1 - 0.035 13.8 0.2 0.97 9.2 0.0 2.8 2 1 0 2 2 2 0 Phage protein GP46 Sushi_2 PF09014.10 EPE35587.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain HRXXH PF13933.6 EPE35588.1 - 0.003 17.2 5.0 0.0056 16.3 5.0 1.6 1 1 0 1 1 1 1 Putative peptidase family Sushi_2 PF09014.10 EPE35588.1 - 0.23 11.4 1.3 0.34 10.8 0.3 1.9 2 1 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain Bac_luciferase PF00296.20 EPE35589.1 - 1e-51 176.2 0.0 1.4e-51 175.8 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF4412 PF14371.6 EPE35589.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4412) Cullin PF00888.22 EPE35591.1 - 4.4e-168 560.7 0.4 5.5e-168 560.4 0.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EPE35591.1 - 4.7e-26 90.6 0.6 1.5e-25 89.0 0.6 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Bac_thur_toxin PF01338.18 EPE35591.1 - 0.0023 17.4 0.0 0.0085 15.6 0.1 1.9 2 0 0 2 2 2 1 Bacillus thuringiensis toxin Pkinase PF00069.25 EPE35592.1 - 2.3e-15 56.7 0.0 2.5e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE35592.1 - 6.6e-05 22.3 0.0 7.8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EPE35592.1 - 0.00043 19.7 0.1 0.26 10.6 0.0 2.1 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EPE35592.1 - 0.041 12.9 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 EPE35592.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EPE35592.1 - 0.14 10.9 0.3 0.97 8.1 0.1 1.9 1 1 1 2 2 2 0 Fungal protein kinase Nup192 PF11894.8 EPE35593.1 - 0 1399.7 0.6 0 1399.4 0.6 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF2202 PF09968.9 EPE35593.1 - 0.11 12.3 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) CLU PF13236.6 EPE35593.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Clustered mitochondria PI3_PI4_kinase PF00454.27 EPE35594.1 - 7.3e-52 176.7 0.0 1.5e-51 175.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EPE35594.1 - 1.7e-29 102.9 0.7 1.1e-28 100.3 0.1 2.9 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 EPE35594.1 - 2.9e-10 39.8 0.1 8.4e-10 38.3 0.1 1.8 1 0 0 1 1 1 1 FATC domain Serine_rich PF08824.10 EPE35594.1 - 0.012 15.7 0.7 0.11 12.5 0.7 2.8 1 0 0 1 1 1 0 Serine rich protein interaction domain Ferritin_2 PF13668.6 EPE35595.1 - 3.3e-37 127.7 2.3 5.3e-37 127.1 2.3 1.3 1 0 0 1 1 1 1 Ferritin-like domain VanY PF02557.17 EPE35595.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Spb1_C PF07780.12 EPE35596.1 - 4.9e-82 274.7 15.9 4.9e-82 274.7 15.9 3.1 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 EPE35596.1 - 2.3e-56 190.7 0.1 4e-56 189.9 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EPE35596.1 - 2.4e-51 173.8 10.8 2.4e-51 173.8 10.8 4.4 3 1 1 4 4 4 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 EPE35596.1 - 0.0082 16.0 0.0 0.024 14.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain HrpB2 PF09487.10 EPE35596.1 - 0.076 13.4 0.3 0.24 11.9 0.3 1.8 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) WD40 PF00400.32 EPE35597.1 - 7.8e-10 39.2 8.4 0.054 14.4 0.1 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE35597.1 - 4.1e-06 27.0 0.0 0.99 9.8 0.0 5.3 4 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPE35597.1 - 0.48 9.0 5.7 6.6 5.3 0.2 3.3 2 2 2 4 4 4 0 Nucleoporin Nup120/160 Glyco_hydro_16 PF00722.21 EPE35598.1 - 2.4e-13 50.0 1.9 9.6e-13 48.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.18 EPE35599.1 - 3.1e-16 59.2 2.0 4.7e-16 58.6 2.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EPE35599.1 - 1.5e-08 34.7 12.1 1.1e-05 25.6 5.8 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EPE35599.1 - 0.00081 19.7 14.6 0.04 14.4 5.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 EPE35599.1 - 0.049 14.3 0.7 1.3 9.7 0.3 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats PDGLE PF13190.6 EPE35599.1 - 0.081 12.8 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 PDGLE domain zf-C2H2_4 PF13894.6 EPE35599.1 - 0.37 11.7 20.1 0.27 12.2 4.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE35599.1 - 0.55 10.6 3.7 1.4 9.3 3.7 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 EPE35599.1 - 1.6 8.9 4.1 4.1 7.6 4.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain RasGEF PF00617.19 EPE35600.1 - 6e-60 202.5 0.1 1e-59 201.7 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EPE35600.1 - 4.9e-26 91.0 0.9 1.1e-25 89.9 0.2 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.28 EPE35600.1 - 9.5e-15 53.9 0.1 1.9e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPE35600.1 - 2.1e-13 49.9 0.2 4.9e-13 48.7 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EPE35600.1 - 1.3e-12 47.1 0.1 2.6e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 EPE35600.1 - 0.00015 21.7 0.0 0.00036 20.6 0.0 1.6 1 0 0 1 1 1 1 WW domain CobT PF06213.12 EPE35600.1 - 3.4 7.0 7.2 16 4.8 0.0 2.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT HTH_Tnp_Tc3_2 PF01498.18 EPE35602.1 - 2.4e-07 30.9 0.8 5.2e-07 29.8 0.8 1.6 1 0 0 1 1 1 1 Transposase DNApol_Exo PF18136.1 EPE35603.1 - 1.6e-106 355.6 0.0 2.9e-106 354.7 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EPE35603.1 - 1.6e-56 192.0 0.0 2.6e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 EPE35603.1 - 0.0053 16.5 0.2 0.062 13.0 0.2 2.3 1 1 0 1 1 1 1 3'-5' exonuclease DUF5484 PF17583.2 EPE35603.1 - 0.09 12.5 0.3 0.24 11.1 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5484) zf-C3HC4_3 PF13920.6 EPE35604.1 - 1.6e-10 40.7 11.0 2.4e-10 40.1 11.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE35604.1 - 2e-07 30.8 11.0 3.3e-07 30.1 11.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EPE35604.1 - 2.6e-07 30.4 14.7 4.4e-07 29.6 14.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE35604.1 - 1.7e-06 27.9 13.1 2.7e-06 27.2 13.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EPE35604.1 - 3.1e-06 26.9 13.6 5e-06 26.3 13.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE35604.1 - 3.3e-06 27.3 12.7 5.1e-06 26.7 12.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EPE35604.1 - 2.3e-05 24.3 6.8 2.3e-05 24.3 6.8 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 EPE35604.1 - 0.0086 15.9 9.8 0.016 15.0 9.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EPE35604.1 - 0.019 15.2 9.6 0.038 14.3 9.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EPE35604.1 - 0.027 14.3 4.0 0.047 13.6 4.0 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EPE35604.1 - 0.23 11.6 11.8 0.45 10.7 11.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING VWC PF00093.18 EPE35604.1 - 1.3 9.4 7.9 2.1 8.7 7.9 1.3 1 0 0 1 1 1 0 von Willebrand factor type C domain UPF0052 PF01933.18 EPE35605.1 - 3e-61 207.2 0.0 4.1e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 RRM_1 PF00076.22 EPE35607.1 - 8.4e-09 35.1 0.1 2e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAF20 PF17052.5 EPE35607.1 - 0.51 10.5 12.3 0.65 10.2 0.4 2.4 2 0 0 2 2 2 0 Cap associated factor Cupin_8 PF13621.6 EPE35608.1 - 1.6e-57 195.2 0.0 1.9e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EPE35608.1 - 0.00053 19.5 0.0 0.00096 18.7 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein 2OG-FeII_Oxy_5 PF13759.6 EPE35608.1 - 0.093 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase WSC PF01822.19 EPE35609.1 - 5.2e-36 122.7 22.0 2.6e-20 72.4 6.7 4.5 3 1 0 3 3 3 2 WSC domain peroxidase PF00141.23 EPE35609.1 - 1.4e-18 67.5 0.0 3.1e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.18 EPE35609.1 - 0.028 14.4 0.1 0.071 13.1 0.1 1.6 1 0 0 1 1 1 0 Photosystem I psaG / psaK S1 PF00575.23 EPE35610.1 - 3.5e-84 277.2 32.3 1.2e-14 54.4 2.2 12.9 12 0 0 12 12 12 10 S1 RNA binding domain Suf PF05843.14 EPE35610.1 - 2.4e-10 40.9 0.0 0.015 15.3 0.0 4.5 2 1 2 4 4 4 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EPE35610.1 - 2.6e-08 34.0 0.1 0.57 11.1 0.0 4.7 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPE35610.1 - 3.9e-06 27.3 0.1 3.3 8.3 0.0 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 EPE35610.1 - 6.8e-06 25.9 9.3 2.9 7.9 0.0 6.3 7 0 0 7 7 7 3 RNase II-type exonuclease C-terminal S1 domain S1_2 PF13509.6 EPE35610.1 - 0.00017 21.6 0.2 4.2 7.5 0.0 5.0 5 0 0 5 5 5 2 S1 domain PCB_OB PF17092.5 EPE35610.1 - 0.00051 20.8 11.1 0.39 11.5 0.1 8.0 6 3 4 10 10 10 1 Penicillin-binding protein OB-like domain NRDE-2 PF08424.10 EPE35610.1 - 0.00081 18.6 1.1 0.027 13.6 1.0 2.9 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference TPR_16 PF13432.6 EPE35610.1 - 0.011 16.4 0.0 0.34 11.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPE35610.1 - 0.11 13.2 0.0 4 8.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Nop14 PF04147.12 EPE35610.1 - 5.9 5.0 23.1 11 4.1 23.1 1.4 1 0 0 1 1 1 0 Nop14-like family Lar_N PF09861.9 EPE35611.1 - 0.03 13.5 0.1 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Lactate racemase N-terminal domain DUF5427 PF10310.9 EPE35611.1 - 8.2 5.3 32.9 0.013 14.4 4.4 3.3 1 1 2 3 3 3 0 Family of unknown function (DUF5427) DOT1 PF08123.13 EPE35612.1 - 4.6e-75 251.6 0.0 7.4e-75 251.0 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 EPE35612.1 - 0.018 15.8 0.1 0.046 14.4 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EPE35612.1 - 0.044 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF3053 PF11254.8 EPE35612.1 - 1.9 8.0 4.6 7 6.2 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3053) ATG16 PF08614.11 EPE35613.1 - 1e-53 182.6 20.2 1.1e-53 182.4 20.2 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 EPE35613.1 - 0.00038 20.0 10.4 0.00042 19.9 10.4 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 HAUS-augmin3 PF14932.6 EPE35613.1 - 0.0085 15.7 10.5 0.0085 15.7 10.5 1.8 1 1 0 2 2 2 1 HAUS augmin-like complex subunit 3 DUF4201 PF13870.6 EPE35613.1 - 0.024 14.4 15.1 0.17 11.6 15.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) LMBR1 PF04791.16 EPE35613.1 - 0.043 12.7 5.0 0.042 12.8 5.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Prominin PF05478.11 EPE35613.1 - 0.15 10.0 5.1 0.17 9.8 5.1 1.1 1 0 0 1 1 1 0 Prominin Macoilin PF09726.9 EPE35613.1 - 0.26 9.8 10.2 0.26 9.8 10.2 1.1 1 0 0 1 1 1 0 Macoilin family UPF0242 PF06785.11 EPE35613.1 - 1.1 9.4 15.6 2.7 8.0 15.5 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 EPE35613.1 - 1.1 8.5 18.3 16 4.7 18.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 EPE35613.1 - 1.2 9.5 14.3 43 4.5 6.3 3.2 1 1 1 2 2 2 0 Csm1 N-terminal domain Atg14 PF10186.9 EPE35613.1 - 1.4 7.9 14.2 2.3 7.2 14.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Bap31_Bap29_C PF18035.1 EPE35613.1 - 1.9 8.6 12.2 0.32 11.0 7.6 2.2 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain APG6_N PF17675.1 EPE35613.1 - 5.3 7.6 25.2 25 5.4 16.4 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region Mod_r PF07200.13 EPE35613.1 - 5.5 7.1 19.4 3.3e+02 1.3 18.9 2.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF4349 PF14257.6 EPE35613.1 - 6.3 6.2 14.8 1.8 8.0 8.5 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) Ras PF00071.22 EPE35614.1 - 1.6e-56 190.4 0.1 1.8e-56 190.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE35614.1 - 6.8e-32 110.2 0.0 9.7e-32 109.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE35614.1 - 1.3e-12 47.5 0.0 1.6e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPE35614.1 - 1e-07 32.0 0.0 1.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EPE35614.1 - 3.8e-06 26.4 0.0 4.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EPE35614.1 - 3.4e-05 23.5 0.0 0.0017 17.9 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EPE35614.1 - 9.5e-05 22.4 0.1 0.0039 17.1 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 EPE35614.1 - 0.0044 16.8 0.1 0.12 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EPE35614.1 - 0.0077 16.2 0.0 0.015 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) cobW PF02492.19 EPE35614.1 - 0.0088 15.6 0.0 0.021 14.4 0.0 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 EPE35614.1 - 0.0093 15.4 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EPE35614.1 - 0.0096 16.2 0.0 0.015 15.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 EPE35614.1 - 0.011 15.5 0.2 0.34 10.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EPE35614.1 - 0.014 15.8 0.0 0.022 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EPE35614.1 - 0.022 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EPE35614.1 - 0.023 14.0 0.1 0.061 12.6 0.0 1.7 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 EPE35614.1 - 0.026 14.1 0.1 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EPE35614.1 - 0.081 12.8 0.4 0.14 12.1 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Glyco_hydro_75 PF07335.11 EPE35614.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 TniB PF05621.11 EPE35614.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 EPE35614.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 EPE35614.1 - 0.14 11.3 0.1 0.29 10.3 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 EPE35614.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 NTPase EamA PF00892.20 EPE35615.1 - 2.2e-11 44.1 34.8 5.6e-08 33.0 4.8 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF3955 PF13127.6 EPE35615.1 - 3.1e-08 33.3 3.2 1.4e-07 31.2 2.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3955) PUNUT PF16913.5 EPE35615.1 - 3e-06 26.7 0.0 3e-06 26.7 0.0 2.6 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 EPE35615.1 - 1.3e-05 24.9 7.9 1.3e-05 24.9 7.9 2.3 2 1 0 2 2 2 1 Solute carrier family 35 UAA PF08449.11 EPE35615.1 - 4.7e-05 22.7 10.8 4.7e-05 22.7 10.8 1.9 2 0 0 2 2 2 1 UAA transporter family CRT-like PF08627.10 EPE35615.1 - 0.014 14.4 4.0 0.35 9.8 0.1 2.3 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like TMEM234 PF10639.9 EPE35615.1 - 0.42 10.7 8.0 0.13 12.3 0.8 2.6 2 0 0 2 2 2 0 Putative transmembrane family 234 Heme_oxygenase PF01126.20 EPE35616.1 - 1.8e-14 54.0 0.0 2.2e-12 47.2 0.0 2.8 2 1 0 2 2 2 2 Heme oxygenase Hydrolase_4 PF12146.8 EPE35617.1 - 6.4e-12 45.3 0.0 2e-11 43.7 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPE35617.1 - 2.2e-11 44.8 0.0 3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPE35617.1 - 1.2e-08 34.9 0.0 5.2e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 EPE35617.1 - 3.9e-05 23.4 0.5 6.5e-05 22.6 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase PGAP1 PF07819.13 EPE35617.1 - 0.0086 15.8 0.2 0.016 14.9 0.2 1.4 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 EPE35617.1 - 0.017 14.7 0.2 0.026 14.1 0.2 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 EPE35617.1 - 0.025 14.4 0.1 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase LIP PF03583.14 EPE35617.1 - 0.067 12.5 0.8 0.1 11.9 0.8 1.2 1 0 0 1 1 1 0 Secretory lipase Abhydrolase_5 PF12695.7 EPE35617.1 - 0.074 12.8 0.3 0.13 12.0 0.3 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Epimerase PF01370.21 EPE35618.1 - 1.4e-11 44.4 0.0 1.9e-10 40.7 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPE35618.1 - 9.9e-07 28.8 0.2 2.5e-06 27.5 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EPE35618.1 - 1.3e-06 28.2 0.2 2e-06 27.5 0.1 1.5 2 1 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 EPE35618.1 - 3.3e-05 23.0 0.1 0.0011 18.0 0.1 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EPE35618.1 - 3.8e-05 23.0 0.0 0.00014 21.2 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 EPE35618.1 - 0.00034 21.0 0.1 0.00066 20.1 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EPE35618.1 - 0.0013 17.9 0.1 0.0022 17.2 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 EPE35619.1 - 4e-09 35.9 0.0 8.9e-08 31.5 0.0 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE35619.1 - 1.6e-08 34.5 13.9 2.8e-08 33.7 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transformer PF06495.11 EPE35619.1 - 0.072 13.2 5.3 1 9.4 4.5 2.2 2 0 0 2 2 2 0 Fruit fly transformer protein CorA PF01544.18 EPE35620.1 - 2.5e-12 46.7 0.0 4.3e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CorA PF01544.18 EPE35621.1 - 6.8e-13 48.6 0.5 1.4e-12 47.5 0.2 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein ATPase_gene1 PF09527.10 EPE35621.1 - 0.0034 17.5 0.6 0.0067 16.6 0.6 1.5 1 0 0 1 1 1 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DUF4335 PF14233.6 EPE35621.1 - 0.0086 16.0 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4335) SYCP2_ARLD PF18581.1 EPE35621.1 - 0.049 13.6 0.8 0.094 12.7 0.8 1.4 1 0 0 1 1 1 0 Synaptonemal complex 2 armadillo-repeat-like domain FumaraseC_C PF10415.9 EPE35622.1 - 0.14 12.6 0.6 0.87 10.1 0.4 2.2 2 0 0 2 2 2 0 Fumarase C C-terminus Nucleo_P87 PF07267.11 EPE35623.1 - 5.4 5.7 7.7 5.8 5.7 7.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HET PF06985.11 EPE35624.1 - 3.8e-28 98.7 0.0 6e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clr2 PF10383.9 EPE35624.1 - 0.029 15.2 0.0 0.091 13.5 0.0 1.8 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 DUF4395 PF14340.6 EPE35625.1 - 0.13 12.6 1.8 0.37 11.1 0.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4395) DUF4231 PF14015.6 EPE35625.1 - 0.65 10.5 3.9 0.91 10.0 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) HET PF06985.11 EPE35626.1 - 0.00026 21.4 1.0 0.36 11.2 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Mitochondr_Som1 PF11093.8 EPE35626.1 - 0.094 12.7 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial export protein Som1 APH PF01636.23 EPE35628.1 - 3.4e-08 33.7 0.0 5.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EPE35628.1 - 3e-07 30.1 0.0 5.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 EPE35628.1 - 8.4e-06 25.5 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EPE35628.1 - 0.0012 18.2 0.1 0.0018 17.5 0.1 1.2 1 0 0 1 1 1 1 Fructosamine kinase Sulfate_transp PF00916.20 EPE35629.1 - 5.4e-66 222.9 28.4 3.6e-65 220.2 28.4 2.0 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EPE35629.1 - 2.8e-11 43.1 0.0 6.3e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EPE35629.1 - 0.0016 18.8 4.8 0.0016 18.8 4.8 4.1 4 1 0 4 4 4 1 Molybdate transporter of MFS superfamily MCRA PF06100.11 EPE35630.1 - 2.2e-206 686.5 0.0 2.6e-206 686.3 0.0 1.0 1 0 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 EPE35630.1 - 2.2e-05 24.6 0.3 4.8e-05 23.5 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE35630.1 - 0.004 16.8 0.0 0.071 12.7 0.2 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 EPE35630.1 - 0.27 10.4 0.3 0.44 9.8 0.3 1.2 1 0 0 1 1 1 0 Thi4 family Sulfotransfer_4 PF17784.1 EPE35631.1 - 3.5e-30 105.5 0.0 3.9e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EPE35631.1 - 0.017 15.5 0.2 0.055 13.8 0.1 1.8 1 1 0 1 1 1 0 Sulfotransferase family Aspzincin_M35 PF14521.6 EPE35633.1 - 0.0016 19.0 0.1 0.13 12.8 0.0 2.5 2 0 0 2 2 2 2 Lysine-specific metallo-endopeptidase DNase_NucA_NucB PF14040.6 EPE35636.1 - 1.1e-13 51.6 0.1 1.4e-13 51.2 0.1 1.2 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Endostatin PF06482.11 EPE35636.1 - 0.21 11.0 0.0 0.29 10.6 0.0 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin STE PF02200.16 EPE35639.1 - 2.9e-56 188.6 0.1 5e-56 187.8 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EPE35639.1 - 5.5e-11 42.3 12.6 3.2e-06 27.3 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE35639.1 - 4.5e-08 33.3 9.6 0.00023 21.8 0.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPE35639.1 - 2e-07 31.1 8.0 8.9e-07 29.1 4.5 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EPE35639.1 - 0.00022 21.4 0.5 0.0077 16.5 0.2 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EPE35639.1 - 0.0024 17.8 5.6 0.0034 17.4 0.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zinc_ribbon_9 PF14369.6 EPE35639.1 - 0.024 14.9 0.2 0.052 13.8 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon zf-Di19 PF05605.12 EPE35639.1 - 0.25 11.7 3.4 0.5 10.7 3.4 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding NmrA PF05368.13 EPE35640.1 - 4.5e-26 91.9 0.0 6.7e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE35640.1 - 7.4e-10 39.0 0.0 1.9e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding TrkA_N PF02254.18 EPE35640.1 - 0.0089 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 EPE35640.1 - 0.015 14.8 0.0 0.029 13.8 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Gin PF10764.9 EPE35641.1 - 0.088 12.8 0.2 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin FlaC_arch PF05377.11 EPE35642.1 - 0.0078 16.6 5.2 0.019 15.3 0.5 2.9 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) Prominin PF05478.11 EPE35642.1 - 0.031 12.2 3.7 0.049 11.6 3.7 1.3 1 0 0 1 1 1 0 Prominin Transcrip_act PF04949.13 EPE35642.1 - 0.061 13.2 1.7 0.29 11.0 0.3 2.6 1 1 2 3 3 3 0 Transcriptional activator TipAS PF07739.13 EPE35642.1 - 0.065 13.8 2.1 0.93 10.0 0.2 3.3 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain DNTTIP1_dimer PF18192.1 EPE35642.1 - 0.083 13.2 0.5 0.43 11.0 0.1 2.4 3 0 0 3 3 3 0 DNTTIP1 dimerisation domain DASH_Duo1 PF08651.10 EPE35642.1 - 0.12 12.2 3.1 0.81 9.5 0.5 3.4 3 0 0 3 3 3 0 DASH complex subunit Duo1 Apolipoprotein PF01442.18 EPE35642.1 - 0.14 12.0 6.6 0.62 9.9 1.3 2.9 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain AI-2E_transport PF01594.16 EPE35642.1 - 0.36 9.9 0.8 0.97 8.5 0.1 2.1 2 1 0 2 2 2 0 AI-2E family transporter Baculo_PEP_C PF04513.12 EPE35642.1 - 0.72 9.9 8.3 0.054 13.5 1.1 2.9 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 EPE35642.1 - 1.3 9.4 4.5 2.4 8.6 0.4 3.4 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ApoLp-III PF07464.11 EPE35642.1 - 1.7 8.7 11.0 5.3 7.1 0.8 3.9 5 0 0 5 5 5 0 Apolipophorin-III precursor (apoLp-III) AAA PF00004.29 EPE35643.1 - 4.3e-16 59.5 0.0 1.7e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EPE35643.1 - 1.2e-06 28.6 0.0 2.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPE35643.1 - 2e-05 25.1 0.1 0.00038 20.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EPE35643.1 - 0.0014 18.9 0.0 0.0037 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 EPE35643.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Zot PF05707.12 EPE35643.1 - 0.076 12.7 0.1 0.91 9.1 0.0 2.2 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) DUF89 PF01937.19 EPE35644.1 - 3.4e-131 437.4 0.0 4.8e-131 436.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF5480 PF17576.2 EPE35644.1 - 0.2 11.6 0.5 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5480) APH PF01636.23 EPE35645.1 - 8.1e-08 32.5 0.8 3.6e-07 30.3 0.8 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EPE35645.1 - 0.00052 19.4 0.0 0.002 17.5 0.0 1.7 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 EPE35645.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EPE35645.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1514 PF07438.11 EPE35646.1 - 0.26 11.2 0.0 1.6 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) ABC_membrane PF00664.23 EPE35648.1 - 7.5e-80 268.5 42.5 1.9e-44 152.4 15.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EPE35648.1 - 3.8e-65 218.6 0.0 3e-33 115.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EPE35648.1 - 2.8e-15 56.4 5.3 7e-06 25.6 0.8 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EPE35648.1 - 3.1e-08 33.7 0.1 0.0022 17.9 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 EPE35648.1 - 5.3e-08 33.2 0.1 0.018 15.3 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EPE35648.1 - 2.7e-07 30.2 2.8 0.0026 17.5 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EPE35648.1 - 5.4e-07 29.7 0.8 0.006 16.4 0.0 3.3 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EPE35648.1 - 8.7e-07 29.5 1.0 0.08 13.3 0.1 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 EPE35648.1 - 1.8e-06 27.8 0.5 0.078 12.7 0.0 3.2 4 0 0 4 4 4 2 AAA domain ABC_ATPase PF09818.9 EPE35648.1 - 2.3e-06 26.7 0.7 0.014 14.2 0.0 3.6 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 EPE35648.1 - 2.7e-06 28.0 5.6 0.0033 18.0 0.1 3.1 3 1 0 3 3 2 2 AAA domain AAA_15 PF13175.6 EPE35648.1 - 1.9e-05 24.6 0.4 0.03 14.0 0.1 2.3 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 EPE35648.1 - 0.00053 20.2 1.0 0.38 11.0 0.1 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 EPE35648.1 - 0.00076 19.1 0.2 0.68 9.5 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EPE35648.1 - 0.00093 19.6 3.0 1.5 9.3 0.0 4.8 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EPE35648.1 - 0.0071 15.9 0.0 2.3 7.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region ATP-synt_ab PF00006.25 EPE35648.1 - 0.0077 15.9 0.1 1.9 8.1 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 EPE35648.1 - 0.0085 16.6 0.0 6.7 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EPE35648.1 - 0.0095 15.9 0.1 9.8 6.2 0.0 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EPE35648.1 - 0.012 15.4 0.1 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EPE35648.1 - 0.012 15.4 0.1 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 EPE35648.1 - 0.037 14.4 0.1 23 5.3 0.0 3.2 3 1 0 3 3 2 0 AAA domain DUF87 PF01935.17 EPE35648.1 - 0.038 14.1 0.2 1.6 8.7 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 EPE35648.1 - 0.048 13.8 0.2 4.8 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EPE35648.1 - 0.051 13.3 0.5 6.9 6.3 0.0 2.6 3 0 0 3 3 2 0 Cytidylate kinase DUF3987 PF13148.6 EPE35648.1 - 0.06 12.3 0.0 2.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PRK PF00485.18 EPE35648.1 - 0.072 12.8 0.0 7 6.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family IstB_IS21 PF01695.17 EPE35648.1 - 0.086 12.6 1.5 16 5.2 0.0 4.2 5 0 0 5 5 5 0 IstB-like ATP binding protein NB-ARC PF00931.22 EPE35648.1 - 0.1 11.8 0.3 16 4.5 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain ATPase_2 PF01637.18 EPE35648.1 - 0.12 12.3 0.8 2.1 8.2 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EPE35648.1 - 0.18 12.2 0.2 45 4.5 0.0 3.2 3 0 0 3 3 3 0 RNA helicase Rad17 PF03215.15 EPE35648.1 - 0.19 11.6 0.0 18 5.2 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase PF06745.13 EPE35648.1 - 0.2 11.0 1.0 10 5.4 0.1 3.1 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 EPE35648.1 - 0.2 11.4 0.8 12 5.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain SLATT_5 PF18160.1 EPE35648.1 - 0.54 9.6 3.2 3.6 6.9 3.2 2.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 zf-LITAF-like PF10601.9 EPE35648.1 - 0.73 10.1 3.6 0.45 10.8 0.5 2.4 2 0 0 2 2 1 0 LITAF-like zinc ribbon domain FSH1 PF03959.13 EPE35649.1 - 1.3e-30 106.7 0.0 3.1e-25 89.1 0.0 2.1 2 0 0 2 2 2 2 Serine hydrolase (FSH1) ketoacyl-synt PF00109.26 EPE35650.1 - 2.2e-71 240.4 0.0 5.6e-71 239.1 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EPE35650.1 - 2.4e-61 206.8 0.3 6.9e-61 205.3 0.3 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EPE35650.1 - 2.7e-53 181.5 0.0 4.9e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EPE35650.1 - 1.9e-52 178.3 0.0 3.1e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EPE35650.1 - 2.9e-41 140.2 0.0 1.4e-40 138.0 0.0 2.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EPE35650.1 - 7.9e-20 71.4 0.0 1.2e-18 67.6 0.0 2.9 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EPE35650.1 - 2.1e-16 59.9 2.1 1.7e-15 57.0 0.2 3.0 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 EPE35650.1 - 5e-14 53.5 0.0 1.4e-13 52.0 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPE35650.1 - 6.3e-10 39.1 0.6 2.9e-09 37.0 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 EPE35650.1 - 7.5e-09 35.5 0.3 7.5e-09 35.5 0.3 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 EPE35650.1 - 3.3e-07 30.2 0.3 1.1e-06 28.5 0.3 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EPE35650.1 - 3.3e-06 27.4 0.4 8.3e-06 26.1 0.4 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EPE35650.1 - 0.0001 21.8 0.1 0.00031 20.2 0.1 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 EPE35650.1 - 0.0015 18.0 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EPE35650.1 - 0.0076 15.8 1.5 0.017 14.7 0.1 2.3 2 0 0 2 2 2 1 NmrA-like family ACP_syn_III PF08545.10 EPE35650.1 - 0.069 13.0 0.1 0.25 11.2 0.1 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sec23_helical PF04815.15 EPE35650.1 - 0.07 13.0 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 1 0 Sec23/Sec24 helical domain Semialdhyde_dh PF01118.24 EPE35650.1 - 0.17 12.3 0.3 32 5.0 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_kinase PF01513.21 EPE35651.1 - 3.8e-48 164.2 0.0 6.8e-48 163.3 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase Acyltransferase PF01553.21 EPE35652.1 - 1.7e-25 89.2 0.0 2.5e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EPE35652.1 - 1.4e-11 44.3 0.0 2.8e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Pkinase PF00069.25 EPE35654.1 - 1.6e-20 73.6 0.0 2.4e-19 69.8 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE35654.1 - 1e-08 34.8 0.0 1.7e-07 30.8 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE35654.1 - 0.017 14.4 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF87 PF01935.17 EPE35654.1 - 0.044 13.9 0.8 0.11 12.6 0.3 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain Choline_kinase PF01633.20 EPE35654.1 - 0.11 12.1 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase p450 PF00067.22 EPE35655.1 - 2.9e-43 148.3 0.0 1.1e-37 129.9 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 Peptidase_S41_N PF11918.8 EPE35656.1 - 1.1e-06 28.9 0.0 2.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Peptidase_S41 PF03572.18 EPE35656.1 - 2.6e-06 27.1 0.0 4.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 APH PF01636.23 EPE35657.1 - 4.1e-15 56.4 0.0 7.7e-15 55.5 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE35657.1 - 9.2e-07 28.7 0.0 1.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EPE35657.1 - 0.053 12.8 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase HnRNPA1 PF11627.8 EPE35657.1 - 0.13 12.5 0.3 0.24 11.6 0.3 1.4 1 0 0 1 1 1 0 Nuclear factor hnRNPA1 DUF1679 PF07914.11 EPE35657.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Acyl_transf_3 PF01757.22 EPE35660.1 - 4.7e-20 71.9 19.3 6.4e-20 71.5 19.3 1.1 1 0 0 1 1 1 1 Acyltransferase family Glyco_hydro_42C PF08533.10 EPE35662.1 - 0.045 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain Nucleo_P87 PF07267.11 EPE35663.1 - 0.3 9.9 9.5 0.36 9.7 9.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Med3 PF11593.8 EPE35666.1 - 9.8 5.2 9.7 13 4.8 9.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HET PF06985.11 EPE35667.1 - 4.7e-39 134.0 2.7 1.1e-38 132.9 2.7 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4003 PF13170.6 EPE35667.1 - 0.063 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Fibrillarin PF01269.17 EPE35669.1 - 4.7e-104 346.5 0.0 5.7e-104 346.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EPE35669.1 - 1.2e-05 25.2 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EPE35669.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 EPE35669.1 - 0.02 14.6 0.0 0.039 13.6 0.0 1.5 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Peptidase_M20 PF01546.28 EPE35670.1 - 3.9e-28 98.6 0.0 2.2e-24 86.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EPE35670.1 - 6.6e-23 81.4 0.0 1.4e-17 64.0 0.0 2.7 3 0 0 3 3 3 2 Peptidase family M28 PA PF02225.22 EPE35670.1 - 8.7e-13 48.1 0.3 2.4e-12 46.7 0.1 1.8 2 0 0 2 2 2 1 PA domain TFR_dimer PF04253.15 EPE35670.1 - 4.8e-10 39.6 0.1 8.4e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain M20_dimer PF07687.14 EPE35670.1 - 0.0011 18.9 0.0 0.003 17.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.16 EPE35671.1 - 6.2e-27 94.5 48.3 9.4e-27 93.8 43.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EPE35671.1 - 1.3e-05 24.7 8.6 1.3e-05 24.7 8.6 2.6 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB Phage_holin_5_2 PF16079.5 EPE35671.1 - 0.023 15.0 0.5 0.023 15.0 0.5 3.9 6 1 1 7 7 7 0 Phage holin family Hol44, in holin superfamily V Condensation PF00668.20 EPE35672.1 - 0 1370.7 0.0 4.6e-60 203.6 0.0 12.2 11 2 0 11 11 11 10 Condensation domain AMP-binding PF00501.28 EPE35672.1 - 0 1279.7 0.1 7.4e-83 278.5 0.0 5.3 5 0 0 5 5 5 5 AMP-binding enzyme PP-binding PF00550.25 EPE35672.1 - 1.4e-70 233.6 14.8 2.4e-12 47.0 0.1 7.8 7 0 0 7 7 7 7 Phosphopantetheine attachment site Transferase PF02458.15 EPE35672.1 - 1.1e-11 44.1 0.1 0.04 12.6 0.0 5.4 5 0 0 5 5 5 5 Transferase family AMP-binding_C PF13193.6 EPE35672.1 - 2.3e-10 41.3 0.0 0.43 11.6 0.0 5.6 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain DUF5122 PF17164.4 EPE35672.1 - 0.21 11.9 2.4 17 5.8 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller DUF3510 PF12022.8 EPE35672.1 - 0.41 11.0 2.0 19 5.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) ABC_tran PF00005.27 EPE35673.1 - 2.2e-44 151.3 0.0 2.6e-24 86.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPE35673.1 - 1.4e-30 106.9 30.1 3.8e-26 92.3 14.8 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EPE35673.1 - 1e-09 38.2 1.4 0.014 14.9 0.1 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EPE35673.1 - 3.4e-06 27.1 0.1 0.0018 18.1 0.0 3.4 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EPE35673.1 - 5.1e-06 26.5 0.0 0.0021 18.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EPE35673.1 - 1.4e-05 25.6 0.1 0.021 15.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EPE35673.1 - 4e-05 23.3 0.6 0.055 13.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EPE35673.1 - 4.1e-05 23.6 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EPE35673.1 - 4.3e-05 23.8 0.5 0.02 15.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 EPE35673.1 - 0.00019 22.0 0.1 0.024 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EPE35673.1 - 0.00022 21.7 0.6 0.18 12.2 0.1 3.6 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EPE35673.1 - 0.0004 19.5 0.0 0.75 8.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_7 PF12775.7 EPE35673.1 - 0.0015 18.0 0.0 0.41 10.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 EPE35673.1 - 0.0023 17.5 0.0 0.1 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EPE35673.1 - 0.0023 17.7 0.0 0.092 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 EPE35673.1 - 0.0031 17.6 0.7 0.39 10.8 0.0 2.4 2 0 0 2 2 2 1 Dynamin family DUF815 PF05673.13 EPE35673.1 - 0.0047 16.1 0.1 2.9 7.0 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF815) cobW PF02492.19 EPE35673.1 - 0.0069 16.0 0.7 0.34 10.5 0.3 2.8 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 EPE35673.1 - 0.0076 16.0 1.4 28 4.4 0.1 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein NB-ARC PF00931.22 EPE35673.1 - 0.011 15.0 0.1 2.8 7.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 EPE35673.1 - 0.012 16.0 0.0 2.8 8.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 EPE35673.1 - 0.017 15.3 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EPE35673.1 - 0.022 14.5 0.0 2 8.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EPE35673.1 - 0.047 13.7 0.1 3.7 7.5 0.1 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EPE35673.1 - 0.048 14.2 0.2 6.1 7.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EPE35673.1 - 0.05 13.3 0.1 2.5 7.8 0.1 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EPE35673.1 - 0.066 13.1 0.0 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 EPE35673.1 - 0.079 13.0 0.6 0.22 11.6 0.1 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain Adeno_IVa2 PF02456.15 EPE35673.1 - 0.11 11.3 0.2 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein NACHT PF05729.12 EPE35673.1 - 0.12 12.3 0.6 4.4 7.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain UCR_UQCRX_QCR9 PF05365.12 EPE35673.1 - 0.14 12.1 0.5 0.46 10.5 0.5 1.9 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Rad17 PF03215.15 EPE35673.1 - 0.47 10.4 1.4 0.84 9.5 0.1 2.0 3 0 0 3 3 1 0 Rad17 P-loop domain DUF3464 PF11947.8 EPE35673.1 - 0.48 10.2 1.7 1.8 8.3 0.1 2.4 1 1 1 2 2 2 0 Photosynthesis affected mutant 68 Apt1 PF10351.9 EPE35674.1 - 0.095 11.5 4.1 0.11 11.3 4.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 EPE35674.1 - 0.85 6.7 6.0 0.99 6.4 6.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 EPE35674.1 - 1.2 8.2 19.3 1.6 7.8 19.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Gly_transf_sug PF04488.15 EPE35675.1 - 6.7e-11 42.7 0.0 1.1e-10 42.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EPE35675.1 - 0.0098 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein HET PF06985.11 EPE35676.1 - 6.6e-37 127.1 1.9 6.6e-37 127.1 1.9 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) FMN_red PF03358.15 EPE35677.1 - 3e-24 85.5 0.0 3.8e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EPE35677.1 - 1.6e-05 24.7 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Glyco_transf_90 PF05686.12 EPE35678.1 - 5.6e-14 51.9 1.6 1.3e-09 37.4 0.2 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 Arginase PF00491.21 EPE35679.1 - 2.1e-73 247.3 0.1 2.6e-73 246.9 0.1 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.23 EPE35680.1 - 4.6e-05 23.5 17.2 7.8e-05 22.7 17.1 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF2070 PF09843.9 EPE35680.1 - 9.9 4.3 10.3 13 3.9 10.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HET PF06985.11 EPE35681.1 - 1.7e-19 70.6 0.0 3.6e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2306 PF10067.9 EPE35683.1 - 6.2e-16 58.9 10.1 1.3e-15 57.9 10.1 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) SLATT_1 PF18181.1 EPE35683.1 - 0.15 12.0 5.7 0.44 10.5 1.2 2.4 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 UL45 PF05473.12 EPE35683.1 - 0.17 11.5 0.0 0.69 9.5 0.1 1.9 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like Cnn_1N PF07989.11 EPE35684.1 - 1.8e-22 79.3 8.2 1.8e-22 79.3 8.2 12.1 8 5 6 14 14 14 3 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 EPE35684.1 - 2.3e-14 53.4 11.1 2.3e-14 53.4 11.1 11.8 12 2 1 13 13 13 3 Micro-tubular organiser Mto1 C-term Mto2-binding region ERM PF00769.19 EPE35684.1 - 0.00039 20.3 36.9 0.00039 20.3 36.9 7.9 3 2 4 7 7 7 1 Ezrin/radixin/moesin family ZapB PF06005.12 EPE35684.1 - 0.012 16.0 7.9 0.012 16.0 7.9 12.8 7 3 3 10 10 10 0 Cell division protein ZapB Baculo_PEP_C PF04513.12 EPE35684.1 - 0.76 9.8 29.3 0.71 9.9 1.6 5.5 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2935 PF11155.8 EPE35684.1 - 1.1 9.6 15.0 0.61 10.4 1.9 5.3 2 1 2 4 4 4 0 Domain of unknown function (DUF2935) RrnaAD PF00398.20 EPE35685.1 - 3.4e-05 23.0 0.1 8.9e-05 21.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase JAB PF01398.21 EPE35686.1 - 1.6e-16 60.3 0.0 2.7e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 EPE35686.1 - 2.4e-08 34.1 0.1 5.1e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 EPE35686.1 - 3.5e-06 26.8 0.3 1e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Spc7 PF08317.11 EPE35686.1 - 0.5 9.2 2.9 0.71 8.7 2.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Lactamase_B PF00753.27 EPE35687.1 - 2.2e-20 73.5 2.9 2.9e-20 73.1 2.9 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EPE35687.1 - 0.00012 21.6 0.3 0.00021 20.9 0.3 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ADH_N PF08240.12 EPE35688.1 - 2.5e-19 69.1 0.1 5e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE35688.1 - 4.6e-19 68.7 0.0 7.7e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EPE35688.1 - 0.00019 21.0 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 EPE35688.1 - 0.0033 17.3 0.1 0.0091 15.9 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 EPE35688.1 - 0.022 14.1 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Alk_phosphatase PF00245.20 EPE35689.1 - 1.4e-68 231.8 0.3 2.4e-68 231.0 0.3 1.3 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 EPE35689.1 - 6.9e-07 29.0 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EPE35689.1 - 3.8e-06 26.7 0.0 6.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EPE35689.1 - 0.0005 18.8 0.2 0.00078 18.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 EPE35689.1 - 0.055 12.8 1.7 0.31 10.4 0.2 2.3 3 0 0 3 3 3 0 Metalloenzyme superfamily DUF1501 PF07394.12 EPE35689.1 - 0.062 12.4 0.1 0.098 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) adh_short PF00106.25 EPE35690.1 - 1.4e-18 67.1 0.0 1.9e-17 63.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE35690.1 - 1.5e-13 50.8 0.0 1.2e-12 47.9 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE35690.1 - 2e-05 24.6 0.0 6.2e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 KR domain Lipase_GDSL_2 PF13472.6 EPE35691.1 - 1.1e-08 35.7 0.0 5.7e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE35691.1 - 0.00079 19.5 0.0 0.0025 17.8 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FixP_N PF14715.6 EPE35693.1 - 2.2 8.1 8.7 3.9 7.3 8.7 1.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP TMEM154 PF15102.6 EPE35694.1 - 0.00048 20.0 0.9 0.00093 19.1 0.0 1.9 2 0 0 2 2 2 1 TMEM154 protein family Herpes_gE PF02480.16 EPE35694.1 - 0.0039 16.0 0.1 0.0092 14.8 0.1 1.5 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 EPE35694.1 - 0.016 16.1 0.4 0.063 14.2 0.0 2.2 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Gram_pos_anchor PF00746.21 EPE35694.1 - 0.32 11.0 1.9 0.86 9.6 1.9 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif LapA_dom PF06305.11 EPE35694.1 - 0.54 10.1 2.3 0.94 9.3 2.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain HET PF06985.11 EPE35695.1 - 1.4e-12 48.2 9.0 1.7e-10 41.4 0.9 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) DUF3843 PF12954.7 EPE35695.1 - 0.057 12.4 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) MFS_1 PF07690.16 EPE35697.1 - 6.3e-37 127.3 32.7 8.4e-35 120.3 24.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TagF_N PF09867.9 EPE35697.1 - 0.047 13.7 0.2 0.15 12.1 0.1 1.8 2 0 0 2 2 2 0 TagF N-terminal domain, Type VI secretion system-associated PSI_PsaH PF03244.14 EPE35697.1 - 0.14 11.6 0.4 0.55 9.7 0.2 2.0 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VI Fructosamin_kin PF03881.14 EPE35698.1 - 6.5e-34 117.5 0.0 8.6e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EPE35698.1 - 0.19 11.6 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family NACHT PF05729.12 EPE35699.1 - 0.00016 21.7 0.0 0.0003 20.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.13 EPE35699.1 - 0.001 18.8 0.4 0.0053 16.5 0.4 2.1 1 1 0 1 1 1 1 PGAP1-like protein ANAPC4_WD40 PF12894.7 EPE35699.1 - 0.0013 19.0 0.0 1.3 9.4 0.0 4.3 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF676 PF05057.14 EPE35699.1 - 0.0015 18.1 0.0 0.0044 16.5 0.0 1.8 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF829 PF05705.14 EPE35699.1 - 0.0087 16.0 0.0 0.053 13.4 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.7 EPE35699.1 - 0.012 16.2 0.0 0.041 14.5 0.0 2.0 1 0 0 1 1 1 0 Alpha/beta hydrolase family HET PF06985.11 EPE35701.1 - 3e-20 73.1 0.3 5.7e-20 72.1 0.3 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.23 EPE35702.1 - 8e-14 52.1 0.0 1.7e-13 51.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE35702.1 - 0.0094 15.6 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Tht1 PF04163.12 EPE35702.1 - 0.035 12.9 0.1 0.063 12.0 0.0 1.3 2 0 0 2 2 2 0 Tht1-like nuclear fusion protein Qua1 PF16274.5 EPE35704.1 - 0.022 14.6 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Qua1 domain GatB_N PF02934.15 EPE35705.1 - 2.7e-100 335.3 0.0 3.5e-100 334.9 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EPE35705.1 - 3.5e-18 65.9 0.0 7.9e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 GatB domain STAT1_TAZ2bind PF12162.8 EPE35705.1 - 2.9 7.6 4.2 0.91 9.2 0.8 1.9 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain zf-H2C2 PF09337.10 EPE35706.1 - 9.7e-16 57.7 3.1 2.4e-15 56.5 3.1 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 EPE35706.1 - 2.2e-10 40.5 0.3 4.4e-10 39.5 0.3 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 EPE35706.1 - 1.2e-06 28.8 0.0 2.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EPE35706.1 - 0.0042 17.2 0.0 0.0074 16.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EPE35706.1 - 0.032 14.9 0.0 0.089 13.5 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE35706.1 - 0.034 14.6 0.0 0.26 11.7 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE35706.1 - 0.044 13.7 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Aldose_epim PF01263.20 EPE35707.1 - 7.4e-61 206.1 0.1 9.7e-61 205.7 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Acyl-CoA_dh_1 PF00441.24 EPE35708.1 - 1.9e-42 145.0 0.1 2.8e-42 144.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EPE35708.1 - 7.9e-22 77.3 0.1 1.4e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EPE35708.1 - 2.3e-20 73.4 0.0 4.4e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 EPE35708.1 - 1.8e-18 66.4 0.2 3.9e-18 65.4 0.2 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 EPE35708.1 - 1.3e-08 35.2 0.0 2.9e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain C6 PF01681.17 EPE35708.1 - 0.16 12.5 0.0 0.45 11.1 0.0 1.7 1 0 0 1 1 1 0 C6 domain Cpn60_TCP1 PF00118.24 EPE35709.1 - 1.9e-156 521.5 2.6 2.2e-156 521.4 2.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 EPE35709.1 - 0.023 13.9 0.1 0.048 12.9 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Beta_helix_2 PF18835.1 EPE35709.1 - 0.13 12.0 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase FtsA PF14450.6 EPE35709.1 - 0.91 10.0 3.1 1.3 9.5 2.5 1.8 1 1 0 1 1 1 0 Cell division protein FtsA DUF1996 PF09362.10 EPE35710.1 - 1.7e-81 273.7 4.2 1.7e-81 273.7 4.2 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF1996) Peptidase_M28 PF04389.17 EPE35711.1 - 1.9e-34 119.1 0.0 2.7e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EPE35711.1 - 5.2e-08 32.8 0.1 1.2e-07 31.7 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 FYVE PF01363.21 EPE35712.1 - 0.76 10.0 5.0 0.27 11.4 0.3 2.4 2 0 0 2 2 2 0 FYVE zinc finger Fringe PF02434.16 EPE35713.1 - 1.4e-06 28.0 1.8 0.00058 19.4 1.8 3.1 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 EPE35713.1 - 0.007 16.3 0.4 0.017 15.0 0.4 1.6 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 EPE35713.1 - 0.027 14.3 0.2 0.056 13.3 0.2 1.4 1 0 0 1 1 1 0 PAN-like domain DUF1942 PF09167.11 EPE35713.1 - 0.16 11.9 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1942) DUF3284 PF11687.8 EPE35716.1 - 0.036 13.9 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3284) Fungal_trans PF04082.18 EPE35717.1 - 8.4e-17 61.1 0.3 1.1e-16 60.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE35717.1 - 8e-08 32.3 9.3 8e-08 32.3 9.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RSN1_TM PF13967.6 EPE35717.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport MFS_1 PF07690.16 EPE35718.1 - 1.7e-33 116.0 38.4 2.4e-33 115.6 38.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF155 PF02582.14 EPE35719.1 - 9.3e-49 165.9 0.0 1.5e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cupin_1 PF00190.22 EPE35719.1 - 0.076 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Cupin FeoB_associated PF12669.7 EPE35719.1 - 0.13 12.7 0.2 0.22 12.0 0.2 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Clathrin PF00637.20 EPE35720.1 - 1.5e-20 73.5 0.3 1.2e-19 70.6 0.6 2.2 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_1 PF10366.9 EPE35720.1 - 0.076 13.3 0.2 0.37 11.1 0.2 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.6 EPE35720.1 - 0.29 11.1 1.1 0.68 10.0 1.1 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EPE35720.1 - 0.8 10.1 2.1 2.8 8.3 0.8 2.2 2 0 0 2 2 2 0 Ring finger domain HIP1_clath_bdg PF16515.5 EPE35721.1 - 0.00037 21.0 60.2 0.0011 19.5 4.5 6.4 3 2 3 6 6 6 3 Clathrin-binding domain of Huntingtin-interacting protein 1 3-PAP PF12578.8 EPE35721.1 - 0.15 11.8 4.5 0.44 10.3 0.0 3.7 3 0 0 3 3 3 0 Myotubularin-associated protein Surfac_D-trimer PF09006.11 EPE35721.1 - 0.54 10.2 4.0 14 5.6 0.0 4.4 5 0 0 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation TMF_DNA_bd PF12329.8 EPE35721.1 - 4.4 7.4 55.5 0.3 11.1 8.1 5.8 4 2 0 5 5 5 0 TATA element modulatory factor 1 DNA binding Methyltransf_2 PF00891.18 EPE35722.1 - 1.6e-16 60.3 0.1 2.5e-16 59.6 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 EPE35722.1 - 0.0052 16.8 0.0 0.019 15.0 0.0 2.0 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 EPE35722.1 - 0.027 14.4 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain DUF4241 PF14025.6 EPE35723.1 - 0.22 11.8 4.8 0.3 11.3 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) PMSI1 PF15322.6 EPE35723.1 - 0.3 10.5 3.9 0.39 10.1 3.9 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative SprA-related PF12118.8 EPE35723.1 - 0.5 9.5 12.7 0.62 9.1 12.7 1.1 1 0 0 1 1 1 0 SprA-related family Folliculin PF11704.8 EPE35723.1 - 2 8.3 5.1 3.1 7.6 5.1 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Presenilin PF01080.17 EPE35723.1 - 5.1 5.8 4.4 5.9 5.5 4.4 1.1 1 0 0 1 1 1 0 Presenilin DUF1744 PF08490.12 EPE35724.1 - 2.2e-156 520.5 0.0 3.5e-156 519.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EPE35724.1 - 5e-76 256.0 0.1 8.6e-76 255.2 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EPE35724.1 - 7.9e-16 57.8 0.1 2.3e-13 49.7 0.1 3.1 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EPE35724.1 - 1.6e-07 31.3 0.2 4.5e-07 29.8 0.2 1.7 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EPE35724.1 - 7.8e-06 26.0 0.0 2.6e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily zf-CHY PF05495.12 EPE35724.1 - 7.1 7.2 7.5 2.5 8.6 2.9 2.5 2 0 0 2 2 2 0 CHY zinc finger DUF3767 PF12597.8 EPE35725.1 - 1e-34 118.3 0.0 1e-34 118.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3767) Prefoldin PF02996.17 EPE35725.1 - 0.68 9.9 4.5 1.1 9.2 4.5 1.3 1 0 0 1 1 1 0 Prefoldin subunit Nup88 PF10168.9 EPE35725.1 - 3 5.5 6.8 4 5.1 6.8 1.1 1 0 0 1 1 1 0 Nuclear pore component NmrA PF05368.13 EPE35726.1 - 2e-30 106.1 0.0 5.4e-30 104.7 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE35726.1 - 1.4e-07 31.6 0.0 1.9e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 EPE35726.1 - 0.018 15.3 0.2 0.032 14.5 0.2 1.3 1 0 0 1 1 1 0 TrkA-N domain DUF3632 PF12311.8 EPE35727.1 - 8.2e-24 85.0 0.5 1.3e-23 84.3 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) TRAUB PF08164.12 EPE35728.1 - 6.3 7.4 9.3 0.72 10.4 4.4 1.9 2 0 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal Gly_transf_sug PF04488.15 EPE35730.1 - 1.2e-10 41.9 0.0 2.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF4171 PF13775.6 EPE35734.1 - 0.15 12.5 1.6 0.27 11.7 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) INCENP_ARK-bind PF03941.15 EPE35734.1 - 0.17 11.9 1.2 0.33 10.9 1.2 1.5 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region Nucleo_P87 PF07267.11 EPE35734.1 - 0.46 9.3 2.5 0.5 9.2 2.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Synaptobrevin PF00957.21 EPE35737.1 - 2.2e-31 107.5 0.6 3.1e-31 107.0 0.0 1.5 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 EPE35737.1 - 7.7e-29 99.6 0.0 1.2e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Prominin PF05478.11 EPE35737.1 - 0.18 9.7 0.4 1.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Prominin SUV3_C PF12513.8 EPE35738.1 - 1.7e-17 63.0 0.6 3.6e-17 62.0 0.6 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EPE35738.1 - 7.6e-10 39.1 0.0 2.3e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 EPE35738.1 - 3.3e-06 26.9 0.1 6.6e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 TK PF00265.18 EPE35738.1 - 0.038 13.9 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase HET PF06985.11 EPE35739.1 - 1.9e-24 86.7 0.1 8.9e-24 84.5 0.0 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) FNIP_N PF14636.6 EPE35740.1 - 4.1e-40 138.3 0.4 4.1e-40 138.3 0.4 3.7 4 1 1 5 5 5 1 Folliculin-interacting protein N-terminus FA_desaturase PF00487.24 EPE35740.1 - 0.037 13.8 0.6 0.061 13.1 0.6 1.2 1 0 0 1 1 1 0 Fatty acid desaturase NuA4 PF09340.10 EPE35740.1 - 0.82 9.6 3.1 6.9 6.6 0.1 3.3 4 0 0 4 4 4 0 Histone acetyltransferase subunit NuA4 Acetyltransf_7 PF13508.7 EPE35741.1 - 6.2e-06 26.6 0.0 1.4e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE35741.1 - 2.4e-05 24.6 0.0 3.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE35741.1 - 3e-05 24.0 0.0 8e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPE35741.1 - 0.031 14.3 0.0 0.067 13.3 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE35741.1 - 0.12 12.4 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein IML1 PF12257.8 EPE35742.1 - 3.1e-119 397.4 0.0 4.4e-119 396.8 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EPE35742.1 - 1.3e-27 95.6 0.1 2.7e-27 94.6 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) NopRA1 PF16201.5 EPE35743.1 - 1.1e-66 224.3 6.5 1.1e-66 224.3 2.3 2.8 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 PriA_3primeBD PF17764.1 EPE35743.1 - 0.029 14.3 0.4 3.6 7.5 0.0 3.2 3 0 0 3 3 3 0 3′ DNA-binding domain (3′BD) Sec1 PF00995.23 EPE35745.1 - 7.8e-121 405.1 0.0 9e-121 404.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.23 EPE35746.1 - 1.2e-06 28.3 0.1 2.9e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 G-patch domain adh_short PF00106.25 EPE35747.1 - 6.2e-16 58.4 0.0 1.7e-14 53.7 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE35747.1 - 5.6e-07 29.4 0.0 1.2e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE35747.1 - 4.4e-05 23.5 0.0 8.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE35747.1 - 0.039 13.4 0.2 0.21 11.0 0.2 2.0 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 EPE35748.1 - 1.6e-06 28.1 9.8 4e-06 26.8 9.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0515 PF15135.6 EPE35748.1 - 0.019 14.3 4.0 0.028 13.8 4.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Epimerase PF01370.21 EPE35749.1 - 1.7e-13 50.6 0.1 5.1e-13 49.1 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPE35749.1 - 3.3e-07 29.6 0.0 1.9e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EPE35749.1 - 4.5e-07 29.9 0.0 8.3e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EPE35749.1 - 0.00024 20.6 0.0 0.00049 19.6 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EPE35749.1 - 0.0055 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EPE35749.1 - 0.0083 15.6 0.2 0.23 10.9 0.0 2.4 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EPE35749.1 - 0.12 11.5 0.4 1.2 8.3 0.4 2.1 1 1 0 1 1 1 0 Male sterility protein Stig1 PF04885.13 EPE35750.1 - 0.00021 21.8 22.7 0.00021 21.8 22.7 2.8 2 1 1 3 3 3 1 Stigma-specific protein, Stig1 HEAT_2 PF13646.6 EPE35751.1 - 1.4e-28 99.1 6.1 1.7e-12 47.5 0.1 4.0 2 2 3 5 5 5 2 HEAT repeats HEAT_PBS PF03130.16 EPE35751.1 - 3.2e-19 67.6 2.5 0.026 15.2 0.0 7.1 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.22 EPE35751.1 - 1.9e-09 37.0 4.2 0.054 13.8 0.0 5.8 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 EPE35751.1 - 5.2e-05 23.6 6.2 0.22 12.1 0.1 4.8 4 1 1 5 5 5 2 HEAT-like repeat Arm PF00514.23 EPE35751.1 - 0.024 14.7 0.2 16 5.7 0.0 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EPE35751.1 - 0.17 11.9 0.0 3.1 7.8 0.0 2.7 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Nipped-B_C PF12830.7 EPE35752.1 - 2.1e-53 181.1 0.1 1.1e-49 169.0 0.0 2.6 2 0 0 2 2 2 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EPE35752.1 - 3.6e-06 27.2 0.3 1.8e-05 24.9 0.3 2.4 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 EPE35752.1 - 0.00023 21.2 0.1 0.0032 17.5 0.0 2.6 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EPE35752.1 - 0.013 15.7 4.1 11 6.6 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 EPE35752.1 - 0.025 14.9 5.7 0.31 11.5 0.6 4.7 6 0 0 6 6 6 0 HEAT repeats UPF0147 PF03685.13 EPE35752.1 - 0.38 10.8 3.0 1.2 9.2 0.6 3.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) DJ-1_PfpI PF01965.24 EPE35753.1 - 2.1e-13 50.4 0.0 3.3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family Abhydrolase_3 PF07859.13 EPE35754.1 - 2.4e-54 184.4 0.0 3.7e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EPE35754.1 - 4.3e-08 32.5 0.0 1.8e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EPE35754.1 - 2.9e-05 23.6 0.1 0.0005 19.6 0.1 2.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 EPE35754.1 - 0.0021 17.0 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Esterase_phd PF10503.9 EPE35754.1 - 0.0059 16.1 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Lipase_3 PF01764.25 EPE35754.1 - 0.0064 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EPE35754.1 - 0.012 16.2 1.0 0.041 14.5 1.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EPE35754.1 - 0.014 14.3 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme AXE1 PF05448.12 EPE35754.1 - 0.015 14.0 0.0 0.031 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 EPE35754.1 - 0.015 15.1 0.0 0.082 12.7 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EPE35754.1 - 0.051 12.8 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Eno-Rase_NADH_b PF12242.8 EPE35754.1 - 0.097 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2974 PF11187.8 EPE35754.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 EPE35754.1 - 0.17 11.6 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family HET PF06985.11 EPE35755.1 - 2.2e-10 41.1 0.0 4.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2HC5 PF06221.13 EPE35756.1 - 9.6e-22 76.7 5.7 1.5e-21 76.1 5.7 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Tropomodulin PF03250.14 EPE35756.1 - 0.11 12.5 1.5 0.28 11.3 0.4 2.2 1 1 1 2 2 2 0 Tropomodulin Syja_N PF02383.18 EPE35757.1 - 1.2e-76 258.1 0.0 1.8e-76 257.5 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain DnaJ PF00226.31 EPE35758.1 - 1.6e-14 53.8 0.0 3.1e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Tti2 PF10521.9 EPE35759.1 - 1.9e-80 270.4 6.6 3.1e-79 266.4 6.6 2.3 1 1 0 1 1 1 1 Tti2 family PolyA_pol PF01743.20 EPE35760.1 - 2.3e-27 95.9 0.1 5.5e-27 94.7 0.1 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EPE35760.1 - 2.7e-09 36.7 0.0 6.4e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DUF648 PF04890.13 EPE35760.1 - 0.042 13.6 0.2 3.1 7.5 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF648) TRAPPC-Trs85 PF12739.7 EPE35761.1 - 7.5e-113 377.5 0.0 1.4e-112 376.6 0.0 1.4 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit HRXXH PF13933.6 EPE35762.1 - 8.6e-09 35.3 3.9 1.4e-08 34.7 3.9 1.2 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 EPE35762.1 - 2.7e-08 34.5 0.3 5.3e-08 33.5 0.3 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Fungal_lectin_2 PF18647.1 EPE35762.1 - 7.6e-07 29.5 0.7 7.6e-07 29.5 0.7 2.1 2 1 0 2 2 2 1 Alpha-galactosyl-binding fungal lectin TMEM52 PF14979.6 EPE35763.1 - 0.059 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Transmembrane 52 TauD PF02668.16 EPE35764.1 - 1.6e-62 211.8 0.6 1.9e-62 211.5 0.6 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NMD3 PF04981.13 EPE35765.1 - 3.7e-81 272.2 3.5 5.6e-81 271.6 3.5 1.3 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.8 EPE35765.1 - 0.36 10.7 9.5 0.63 10.0 0.2 2.8 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) HypA PF01155.19 EPE35765.1 - 0.39 10.8 6.6 6.6 6.8 0.2 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EPE35765.1 - 2.9 8.0 10.9 7.9e+02 0.2 10.9 2.7 1 1 0 1 1 1 0 Double zinc ribbon Ank_4 PF13637.6 EPE35767.1 - 1.8e-08 34.7 0.4 0.0047 17.5 0.1 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE35767.1 - 6.4e-08 33.1 0.1 0.003 18.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE35767.1 - 1e-06 28.6 1.9 0.015 15.8 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EPE35767.1 - 1.5e-06 28.4 2.6 0.0022 18.4 0.0 4.1 3 1 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.13 EPE35767.1 - 8.5e-05 22.4 0.2 0.0017 18.2 0.2 2.6 1 1 0 1 1 1 1 KilA-N domain Ank_5 PF13857.6 EPE35767.1 - 0.00022 21.5 1.4 2.2 8.7 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF948 PF06103.11 EPE35767.1 - 0.17 12.1 0.4 3.5 7.9 0.1 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 EPE35767.1 - 0.24 10.9 18.4 0.77 9.3 18.4 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit AAA_13 PF13166.6 EPE35767.1 - 0.27 9.8 8.5 0.41 9.2 8.5 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 EPE35767.1 - 0.41 9.5 14.9 3.9 6.3 12.0 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 EPE35767.1 - 0.48 9.7 16.2 0.64 9.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Filament PF00038.21 EPE35767.1 - 0.91 9.0 17.8 2.7 7.5 0.3 2.3 2 0 0 2 2 2 0 Intermediate filament protein UPF0242 PF06785.11 EPE35767.1 - 2.6 8.1 14.3 8.6 6.4 14.3 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 EPE35767.1 - 2.9 7.2 14.8 4.6 6.5 10.4 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 EPE35767.1 - 3.3 5.5 5.0 5.7 4.7 5.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SKA2 PF16740.5 EPE35767.1 - 4.9 7.0 15.9 15 5.4 0.2 3.0 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Cdh1_DBD_1 PF18196.1 EPE35767.1 - 7.1 7.0 7.2 9.5 6.6 1.6 2.6 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Complex1_LYR PF05347.15 EPE35768.1 - 6.1e-08 32.6 2.7 6.1e-08 32.6 2.7 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EPE35768.1 - 0.049 14.4 2.4 0.12 13.2 1.7 2.0 2 0 0 2 2 2 0 Complex1_LYR-like Acetyltransf_1 PF00583.25 EPE35769.1 - 6.4e-16 58.6 0.0 8.4e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE35769.1 - 4.3e-08 33.5 0.0 6.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE35769.1 - 1.8e-07 31.0 0.0 3.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EPE35769.1 - 3.1e-06 27.1 0.0 4.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EPE35769.1 - 0.0012 19.6 0.0 0.0023 18.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPE35769.1 - 0.041 14.0 0.0 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EPE35769.1 - 0.066 12.7 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 EPE35769.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 EPE35769.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_11 PF13414.6 EPE35770.1 - 2.3e-07 30.4 2.0 0.00061 19.4 0.0 4.4 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.17 EPE35770.1 - 3.5e-06 26.7 9.5 0.029 14.4 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EPE35770.1 - 0.017 15.8 0.7 0.017 15.8 0.7 4.3 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPE35770.1 - 0.058 13.7 15.4 0.56 10.5 1.7 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EPE35770.1 - 0.063 13.7 0.3 58 4.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EPE35770.1 - 0.096 13.0 4.0 2.1 8.8 0.1 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 EPE35770.1 - 0.12 12.9 0.8 15 6.1 0.2 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EPE35770.1 - 0.14 12.1 7.6 11 6.1 0.3 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPE35770.1 - 0.8 10.7 12.9 1.1 10.2 1.2 5.2 4 2 2 6 6 6 0 Tetratricopeptide repeat DTW PF03942.15 EPE35771.1 - 0.18 11.5 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 DTW domain Epimerase PF01370.21 EPE35772.1 - 1.3e-21 77.2 0.0 1.7e-20 73.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE35772.1 - 5.7e-10 39.1 0.0 7.2e-09 35.5 0.0 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EPE35772.1 - 7e-06 25.2 0.0 2.4e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EPE35772.1 - 1.6e-05 24.1 0.0 2.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EPE35772.1 - 3.1e-05 23.3 0.0 4.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EPE35772.1 - 0.00018 20.7 0.0 0.0039 16.4 0.1 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EPE35772.1 - 0.002 18.0 0.0 0.0052 16.7 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPE35772.1 - 0.052 13.1 0.3 7.4 6.1 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family AP_endonuc_2 PF01261.24 EPE35772.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Cys_Met_Meta_PP PF01053.20 EPE35773.1 - 7.7e-08 31.3 0.0 1.1e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme APH PF01636.23 EPE35774.1 - 0.00024 21.1 0.0 0.00078 19.4 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EPE35774.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase GYF PF02213.16 EPE35775.1 - 1.8e-17 62.7 1.2 1.9e-16 59.5 0.3 2.6 2 0 0 2 2 2 1 GYF domain Abhydrolase_3 PF07859.13 EPE35776.1 - 1.9e-46 158.6 0.1 2.4e-46 158.3 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EPE35776.1 - 1e-10 41.1 0.0 2.6e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EPE35776.1 - 0.0024 17.4 0.0 0.033 13.7 0.0 2.4 3 0 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 EPE35776.1 - 0.014 14.9 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EPE35776.1 - 0.017 14.4 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SLED PF12140.8 EPE35776.1 - 0.11 13.0 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 SLED domain Patatin PF01734.22 EPE35776.1 - 0.15 12.2 0.0 0.93 9.6 0.1 2.0 2 0 0 2 2 2 0 Patatin-like phospholipase Fungal_trans PF04082.18 EPE35777.1 - 7.4e-24 84.2 6.4 1.4e-23 83.2 6.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE35777.1 - 4.3e-09 36.3 11.0 9.6e-09 35.2 11.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DTW PF03942.15 EPE35777.1 - 0.042 13.6 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 DTW domain MFS_1 PF07690.16 EPE35778.1 - 4.6e-35 121.2 39.8 4.6e-35 121.2 39.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE35778.1 - 2e-09 36.4 6.9 3.6e-09 35.6 6.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPE35778.1 - 2.7e-08 33.1 14.8 2.7e-08 33.1 14.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Rb_C PF08934.10 EPE35779.1 - 0.05 13.4 0.4 0.074 12.9 0.4 1.2 1 0 0 1 1 1 0 Rb C-terminal domain Keratin_2_head PF16208.5 EPE35779.1 - 5.4 7.1 44.1 6 7.0 30.2 3.4 3 0 0 3 3 3 0 Keratin type II head Abhydrolase_1 PF00561.20 EPE35781.1 - 3.7e-22 79.2 0.4 1.9e-17 63.8 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE35781.1 - 6.6e-18 66.1 0.1 4.9e-17 63.3 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE35781.1 - 1.6e-13 50.5 0.0 8.5e-11 41.6 0.0 2.5 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Esterase PF00756.20 EPE35781.1 - 2.1e-05 24.3 0.9 9.3e-05 22.2 0.9 1.9 1 1 0 1 1 1 1 Putative esterase ELMO_CED12 PF04727.13 EPE35781.1 - 0.083 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 ELMO/CED-12 family Peptidase_S9 PF00326.21 EPE35781.1 - 0.11 12.0 0.1 0.38 10.2 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Cofilin_ADF PF00241.20 EPE35782.1 - 3.6e-18 65.5 0.0 4.5e-18 65.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Aldedh PF00171.22 EPE35785.1 - 1.5e-132 442.4 0.0 1.7e-132 442.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EPE35785.1 - 0.00028 20.1 0.0 0.00061 19.0 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) CdiI_2 PF18593.1 EPE35785.1 - 0.036 14.7 0.1 0.086 13.5 0.1 1.6 1 0 0 1 1 1 0 CdiI immunity protein OSCP PF00213.18 EPE35785.1 - 0.069 13.3 0.3 0.15 12.2 0.3 1.5 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit ATP-synt_D PF01813.17 EPE35785.1 - 0.087 12.6 1.9 0.18 11.6 0.9 1.9 2 0 0 2 2 2 0 ATP synthase subunit D RRM_1 PF00076.22 EPE35786.1 - 8.1e-08 32.0 0.1 1.7e-05 24.6 0.1 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gly-zipper_Omp PF13488.6 EPE35787.1 - 0.0016 18.4 10.1 0.0016 18.4 10.1 2.5 2 1 0 2 2 2 1 Glycine zipper Rick_17kDa_Anti PF05433.15 EPE35787.1 - 0.0046 16.8 20.2 0.0046 16.8 20.2 2.1 2 0 0 2 2 2 1 Glycine zipper 2TM domain ATPase_gene1 PF09527.10 EPE35787.1 - 0.3 11.3 7.2 0.5 10.6 7.2 1.3 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Pkinase PF00069.25 EPE35789.1 - 3.3e-23 82.4 0.0 1.3e-17 64.1 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE35789.1 - 1.7e-10 40.7 0.0 1.3e-06 27.9 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase PEHE PF15275.6 EPE35790.1 - 0.0082 16.8 1.3 0.016 15.8 0.1 2.1 1 1 1 2 2 2 1 PEHE domain Glyco_hydro_125 PF06824.11 EPE35792.1 - 3.1e-182 606.1 0.0 3.5e-182 605.9 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Aminotran_5 PF00266.19 EPE35793.1 - 2e-19 69.8 0.0 5e-19 68.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V MFS_1 PF07690.16 EPE35794.1 - 6.2e-37 127.3 28.3 8.4e-37 126.9 28.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fucose_iso_N1 PF07881.12 EPE35794.1 - 0.21 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain zf-C3H1 PF10650.9 EPE35795.1 - 1.9e-12 46.6 3.2 3.1e-12 46.0 3.2 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain Pox_E2-like PF04497.12 EPE35795.1 - 0.21 10.0 2.2 0.31 9.4 2.2 1.1 1 0 0 1 1 1 0 Poxviridae protein Resolvase PF00239.21 EPE35795.1 - 7.6 6.6 10.9 0.061 13.4 2.1 2.1 2 0 0 2 2 2 0 Resolvase, N terminal domain Myosin_head PF00063.21 EPE35796.1 - 1.4e-266 886.1 0.0 2.8e-266 885.1 0.0 1.6 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 EPE35796.1 - 2e-12 46.7 0.1 4.2e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 EPE35796.1 - 6.8e-11 40.8 266.3 2.9e-08 32.1 108.4 7.0 2 2 2 4 4 4 4 Myosin tail DUF1732 PF08340.11 EPE35796.1 - 0.0038 17.2 1.3 0.0038 17.2 1.3 5.3 6 0 0 6 6 6 2 Domain of unknown function (DUF1732) HALZ PF02183.18 EPE35796.1 - 0.042 14.1 0.3 0.042 14.1 0.3 12.3 16 0 0 16 16 16 0 Homeobox associated leucine zipper AAA_22 PF13401.6 EPE35796.1 - 0.1 12.9 0.0 0.1 12.9 0.0 5.8 5 0 0 5 5 5 0 AAA domain Erf4 PF10256.9 EPE35796.1 - 0.94 9.6 3.5 44 4.2 0.0 4.3 5 0 0 5 5 5 0 Golgin subfamily A member 7/ERF4 family But2 PF09792.9 EPE35797.1 - 6.7e-54 182.2 4.6 6.7e-54 182.2 4.6 3.9 3 1 0 4 4 4 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF4719 PF15843.5 EPE35798.1 - 0.038 14.1 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) Arginase PF00491.21 EPE35799.1 - 0.0078 15.7 0.0 0.0095 15.5 0.0 1.1 1 0 0 1 1 1 1 Arginase family Arginase PF00491.21 EPE35800.1 - 2.8e-65 220.6 0.0 4.7e-39 134.6 0.1 2.0 1 1 1 2 2 2 2 Arginase family UPF0489 PF12640.7 EPE35800.1 - 0.024 14.9 0.2 0.036 14.3 0.2 1.2 1 0 0 1 1 1 0 UPF0489 domain tRNA-synt_2 PF00152.20 EPE35801.1 - 0.0038 16.4 0.0 0.0045 16.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) ABC_tran PF00005.27 EPE35803.1 - 2.4e-06 28.1 0.5 0.0014 19.1 0.2 2.6 1 1 1 2 2 2 2 ABC transporter SMC_N PF02463.19 EPE35803.1 - 3.3e-06 26.7 0.0 0.0078 15.7 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EPE35803.1 - 1.2e-05 25.9 0.1 2.4e-05 24.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EPE35803.1 - 3.1e-05 24.0 0.1 5.8e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EPE35803.1 - 0.00015 21.4 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EPE35803.1 - 0.00035 20.4 0.0 0.00051 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EPE35803.1 - 0.0011 18.9 0.2 0.0032 17.4 0.2 1.8 1 1 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 EPE35803.1 - 0.0017 18.4 0.1 0.038 14.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPE35803.1 - 0.0058 17.0 0.0 0.013 15.9 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EPE35803.1 - 0.0063 16.8 0.4 0.041 14.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EPE35803.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EPE35803.1 - 0.013 15.5 0.2 0.028 14.3 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase DUF2813 PF11398.8 EPE35803.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA_5 PF07728.14 EPE35803.1 - 0.034 14.2 0.0 0.086 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EPE35803.1 - 0.055 13.9 0.0 0.27 11.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EPE35803.1 - 0.093 12.6 0.2 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 NTPase LAGLIDADG_3 PF14528.6 EPE35803.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 LAGLIDADG-like domain Hox9_act PF04617.13 EPE35804.1 - 0.035 14.9 0.2 0.037 14.8 0.2 1.0 1 0 0 1 1 1 0 Hox9 activation region HET PF06985.11 EPE35805.1 - 2.3e-27 96.1 1.4 5.4e-24 85.2 0.1 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Response_reg PF00072.24 EPE35806.1 - 1.3e-20 73.6 0.0 1.7e-14 53.9 0.0 2.5 1 1 1 2 2 2 2 Response regulator receiver domain Pkinase PF00069.25 EPE35807.1 - 1.1e-45 156.0 0.0 1.7e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE35807.1 - 1.2e-23 83.7 0.1 5.1e-23 81.7 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPE35807.1 - 0.011 14.6 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EPE35807.1 - 0.041 13.2 0.5 0.41 9.9 0.0 2.3 3 0 0 3 3 3 0 Kinase-like SGL PF08450.12 EPE35808.1 - 6.3e-05 22.7 0.1 0.00073 19.2 0.1 2.1 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Acetyltransf_10 PF13673.7 EPE35809.1 - 5.1e-08 32.9 0.0 1.5e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE35809.1 - 4.9e-06 26.8 0.6 1.1e-05 25.7 0.6 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EPE35809.1 - 0.00011 22.9 0.1 0.00049 20.8 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPE35809.1 - 0.00026 21.1 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 EPE35809.1 - 0.00045 20.6 0.1 0.00084 19.7 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Taq-exonuc PF09281.10 EPE35809.1 - 0.085 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Taq polymerase, exonuclease CRISPR_Cas6 PF10040.9 EPE35809.1 - 0.14 12.8 0.3 0.2 12.4 0.3 1.4 1 1 0 1 1 1 0 CRISPR-associated endoribonuclease Cas6 Fasciclin PF02469.22 EPE35810.1 - 3.2e-29 101.7 0.6 2e-15 57.2 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain SKG6 PF08693.10 EPE35810.1 - 0.0015 17.9 0.4 0.003 16.9 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 EPE35810.1 - 0.015 15.1 0.0 0.046 13.5 0.0 1.8 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM51 PF15345.6 EPE35810.1 - 0.045 13.6 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 MSA-2c PF12238.8 EPE35810.1 - 2.9 7.8 13.5 0.039 14.0 2.0 2.6 3 0 0 3 3 3 0 Merozoite surface antigen 2c CorA PF01544.18 EPE35811.1 - 7.3e-14 51.8 6.8 7.3e-14 51.8 6.8 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2207 PF09972.9 EPE35811.1 - 0.023 13.5 0.1 0.033 13.0 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) M11L PF11099.8 EPE35811.1 - 0.062 13.6 0.4 0.18 12.1 0.1 1.9 2 0 0 2 2 2 0 Apoptosis regulator M11L like FtsX PF02687.21 EPE35811.1 - 0.19 12.2 1.8 0.35 11.4 1.8 1.4 1 0 0 1 1 1 0 FtsX-like permease family Fib_alpha PF08702.10 EPE35811.1 - 1.6 8.9 8.1 5.2 7.2 8.1 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 EPE35811.1 - 3.9 8.1 9.1 10 6.8 0.7 3.2 3 0 0 3 3 3 0 SlyX Asp PF00026.23 EPE35814.1 - 8.8e-14 51.6 0.0 1.4e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease EssA PF10661.9 EPE35814.1 - 0.052 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Mid2 PF04478.12 EPE35814.1 - 0.063 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor PCC_BT PF18140.1 EPE35814.1 - 0.16 12.3 0.8 0.48 10.8 0.8 1.8 1 0 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain Potass_KdpF PF09604.10 EPE35814.1 - 0.89 9.6 8.2 2 8.5 8.2 1.6 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) Jnk-SapK_ap_N PF09744.9 EPE35816.1 - 0.15 12.2 1.3 0.29 11.3 1.3 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APH PF01636.23 EPE35818.1 - 1.8e-11 44.5 0.0 4.4e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family tRNA_bind_3 PF17176.4 EPE35819.1 - 4.6 7.6 10.4 0.69 10.2 2.2 2.9 3 0 0 3 3 3 0 tRNA-binding domain TPR_1 PF00515.28 EPE35820.1 - 4e-24 83.4 6.2 0.00014 21.5 0.5 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 EPE35820.1 - 8.1e-23 78.7 8.2 0.0012 18.8 0.8 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 EPE35820.1 - 7.1e-18 63.3 4.0 0.019 15.1 0.1 7.4 8 0 0 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE35820.1 - 2.3e-17 63.0 14.3 1.1e-16 60.8 0.6 4.1 4 1 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EPE35820.1 - 1.4e-13 51.2 11.5 1.9e-08 34.8 1.2 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EPE35820.1 - 5.3e-12 45.2 1.5 0.00014 21.5 0.1 6.2 6 0 0 6 6 6 2 TPR repeat TPR_7 PF13176.6 EPE35820.1 - 4.1e-09 35.8 2.6 0.68 10.1 0.0 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EPE35820.1 - 4.8e-09 36.3 6.6 0.0061 17.3 0.1 7.5 8 1 1 9 9 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 EPE35820.1 - 1.9e-08 34.7 7.6 0.013 16.0 0.5 5.2 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EPE35820.1 - 1.7e-06 28.2 13.6 0.16 12.3 0.6 7.2 4 2 4 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EPE35820.1 - 3.5e-06 27.1 11.1 0.12 12.6 0.3 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPE35820.1 - 0.0021 18.3 0.1 61 4.3 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPE35820.1 - 0.0027 18.2 7.6 10 7.0 0.1 6.9 9 0 0 9 9 8 1 Tetratricopeptide repeat SNAP PF14938.6 EPE35820.1 - 0.038 13.4 0.5 5.4 6.3 0.0 3.1 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.6 EPE35820.1 - 0.068 13.3 0.1 5.4 7.2 0.0 2.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat CAP PF00188.26 EPE35821.1 - 1.3e-18 68.0 4.2 2e-18 67.4 4.2 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family NeA_P2 PF12312.8 EPE35821.1 - 0.044 13.2 5.1 0.066 12.7 5.1 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Ank_2 PF12796.7 EPE35822.1 - 5.7e-29 100.5 1.6 1.6e-09 38.2 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EPE35822.1 - 5.4e-19 67.7 2.4 0.00082 19.7 0.4 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EPE35822.1 - 3.3e-17 62.6 0.1 2e-07 31.4 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE35822.1 - 2.1e-16 58.3 0.5 0.0087 16.5 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EPE35822.1 - 1.6e-14 53.8 0.2 0.00029 21.1 0.1 3.7 2 2 1 3 3 3 3 Ankyrin repeats (many copies) HET PF06985.11 EPE35822.1 - 1.4e-12 48.2 4.4 1e-09 38.9 0.2 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NACHT PF05729.12 EPE35822.1 - 7.5e-07 29.2 0.0 1.7e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EPE35822.1 - 0.00025 21.5 0.1 0.00097 19.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.14 EPE35822.1 - 0.011 15.0 1.8 0.15 11.3 0.0 2.8 2 1 1 3 3 3 0 KAP family P-loop domain FlaF PF07309.11 EPE35822.1 - 0.045 13.8 0.1 0.38 10.8 0.2 2.3 2 0 0 2 2 2 0 Flagellar protein FlaF AAA_22 PF13401.6 EPE35822.1 - 0.056 13.7 0.0 0.28 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain NESP55 PF06390.12 EPE35823.1 - 0.22 11.1 3.7 0.45 10.1 3.7 1.5 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Atrophin-1 PF03154.15 EPE35823.1 - 7.7 4.7 7.1 13 4.0 7.1 1.2 1 0 0 1 1 1 0 Atrophin-1 family ISK_Channel PF02060.15 EPE35825.1 - 0.19 11.4 0.1 0.4 10.4 0.1 1.4 1 0 0 1 1 1 0 Slow voltage-gated potassium channel TssO PF17561.2 EPE35825.1 - 0.24 11.5 1.8 0.46 10.6 1.8 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssO Sterol_MT_C PF08498.10 EPE35826.1 - 8.4e-29 99.7 0.2 1.4e-28 99.0 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EPE35826.1 - 4.4e-19 68.9 0.0 9.1e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE35826.1 - 8.1e-19 68.1 0.0 1.7e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE35826.1 - 2e-17 63.4 0.0 3e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE35826.1 - 4.5e-12 46.1 0.0 7.8e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EPE35826.1 - 7.1e-12 45.2 0.1 9.9e-12 44.7 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EPE35826.1 - 1.4e-11 45.0 0.0 3.1e-11 43.9 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE35826.1 - 1.8e-10 40.6 0.0 2.9e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EPE35826.1 - 4e-05 23.1 0.0 0.00011 21.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 EPE35826.1 - 0.0003 20.4 0.0 0.00045 19.8 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 EPE35826.1 - 0.00085 18.9 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EPE35826.1 - 0.026 14.5 0.6 0.053 13.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 EPE35826.1 - 0.027 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 EPE35826.1 - 0.055 12.5 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TehB PF03848.14 EPE35826.1 - 0.06 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB MetW PF07021.12 EPE35826.1 - 0.082 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RRM_1 PF00076.22 EPE35827.1 - 1.1e-08 34.8 0.0 1.9e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3089 PF11288.8 EPE35828.1 - 0.00029 20.4 0.1 0.00038 20.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Complex1_LYR PF05347.15 EPE35828.1 - 0.0003 20.8 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF3591 PF12157.8 EPE35828.1 - 0.088 11.4 0.0 0.088 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) Complex1_LYR_2 PF13233.6 EPE35828.1 - 0.13 13.0 0.0 0.16 12.7 0.0 1.3 1 1 0 1 1 1 0 Complex1_LYR-like RAC_head PF16717.5 EPE35829.1 - 1.1e-29 103.3 1.1 1.1e-29 103.3 1.1 3.7 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 EPE35829.1 - 9.9e-19 67.2 0.8 3.9e-18 65.3 0.8 2.1 1 0 0 1 1 1 1 DnaJ domain V_ATPase_I PF01496.19 EPE35829.1 - 3.5 5.4 7.8 5.9 4.7 7.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Acetyltransf_1 PF00583.25 EPE35830.1 - 1e-15 58.0 0.0 1.9e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EPE35830.1 - 8.2e-11 41.7 0.0 1.7e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EPE35830.1 - 1.9e-09 37.8 0.1 4.3e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPE35830.1 - 1.6e-05 24.8 0.0 3.7e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPE35830.1 - 0.082 13.1 0.0 0.61 10.2 0.0 2.4 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase DUF4604 PF15377.6 EPE35831.1 - 0.0067 16.9 2.0 0.0073 16.8 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) LigD_N PF13298.6 EPE35833.1 - 0.084 13.2 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) ubiquitin PF00240.23 EPE35834.1 - 0.0016 18.2 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 EPE35834.1 - 0.0059 17.3 0.0 0.01 16.5 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Nop PF01798.18 EPE35835.1 - 1.1e-80 270.4 0.1 1.1e-80 270.4 0.1 2.2 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EPE35835.1 - 3.2e-16 59.5 1.7 3.2e-16 59.5 1.7 3.8 4 0 0 4 4 4 1 NOP5NT (NUC127) domain bMG10 PF17973.1 EPE35835.1 - 1.1 9.4 4.9 2.4 8.4 2.3 2.3 2 0 0 2 2 2 0 Bacterial Alpha-2-macroglobulin MG10 domain vATP-synt_AC39 PF01992.16 EPE35836.1 - 8.4e-109 364.1 0.0 9.4e-109 364.0 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.22 EPE35837.1 - 1.9e-23 82.5 0.5 6.6e-23 80.7 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 SAE2 PF08573.10 EPE35837.1 - 0.6 11.2 0.1 0.6 11.2 0.1 2.4 3 0 0 3 3 3 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Ribosomal_S2 PF00318.20 EPE35838.1 - 1.3e-26 93.2 0.1 6.8e-15 54.9 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EPE35838.1 - 2.6e-09 38.3 13.6 4.5e-09 37.5 13.6 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus KxDL PF10241.9 EPE35839.1 - 2.6e-31 107.8 0.6 3.5e-31 107.3 0.6 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF3984 PF13136.6 EPE35841.1 - 0.094 12.1 5.9 0.15 11.5 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF2244 PF10003.9 EPE35841.1 - 0.15 11.7 1.6 0.52 10.0 1.4 1.9 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Nup54 PF13874.6 EPE35842.1 - 2.4e-40 137.9 0.0 2.4e-40 137.9 0.0 2.7 3 1 0 3 3 3 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 EPE35842.1 - 2.2e-13 49.5 5.9 4.8e-13 48.4 5.9 1.6 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 EPE35842.1 - 0.00032 21.5 71.3 1.8e+04 -8.6 71.3 3.3 1 1 0 1 1 1 0 Nucleoporin FG repeat region DivIVA PF05103.13 EPE35842.1 - 0.0023 18.0 2.2 0.59 10.2 0.3 2.7 2 0 0 2 2 2 2 DivIVA protein V-SNARE_C PF12352.8 EPE35842.1 - 0.062 13.6 1.9 6 7.2 0.4 2.8 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus YscO-like PF16789.5 EPE35842.1 - 0.88 9.6 10.1 7.6 6.5 9.9 2.3 1 1 0 1 1 1 0 YscO-like protein Ku_C PF03730.14 EPE35842.1 - 2.7 8.7 7.2 21 5.9 6.5 2.7 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm Acetyltransf_3 PF13302.7 EPE35843.1 - 9.4e-13 49.0 0.0 1.4e-12 48.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EPE35843.1 - 0.00035 20.7 0.0 0.00049 20.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE35843.1 - 0.0075 16.5 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family PIG-H PF10181.9 EPE35844.1 - 1.7e-26 91.8 0.2 2.9e-26 91.1 0.2 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.20 EPE35845.1 - 8.6e-33 113.0 0.0 1.2e-31 109.3 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase Ras PF00071.22 EPE35846.1 - 7.6e-16 58.1 0.0 2.5e-12 46.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Arf PF00025.21 EPE35846.1 - 3.8e-05 23.2 0.0 0.22 10.9 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 EPE35846.1 - 0.0055 15.9 0.1 0.0083 15.3 0.1 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Roc PF08477.13 EPE35846.1 - 0.024 14.8 0.1 0.064 13.5 0.1 1.9 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SET PF00856.28 EPE35847.1 - 7.1e-05 23.3 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 SET domain Sugar_tr PF00083.24 EPE35848.1 - 6.8e-84 282.3 26.6 8.2e-84 282.0 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE35848.1 - 8.1e-16 57.9 61.6 5e-15 55.3 32.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily APH PF01636.23 EPE35849.1 - 3.7e-07 30.3 0.1 5.4e-07 29.8 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE35849.1 - 3.3e-06 26.9 0.0 4.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EPE35849.1 - 0.057 12.3 0.0 0.08 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) PSI_PsaH PF03244.14 EPE35850.1 - 0.015 14.8 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VI 3Beta_HSD PF01073.19 EPE35851.1 - 1.9e-34 119.0 0.0 2.6e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPE35851.1 - 8.1e-20 71.3 0.0 2.2e-19 69.9 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE35851.1 - 1.4e-14 54.3 0.0 3.3e-13 49.7 0.0 2.4 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EPE35851.1 - 4.3e-08 32.6 0.0 6.9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EPE35851.1 - 5.8e-08 32.2 0.0 3.1e-06 26.5 0.0 2.2 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 EPE35851.1 - 7.3e-05 22.7 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EPE35851.1 - 0.0055 16.6 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 1 KR domain NmrA PF05368.13 EPE35851.1 - 0.014 14.9 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.15 EPE35851.1 - 0.021 14.0 0.0 0.056 12.6 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 EPE35851.1 - 0.039 13.4 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase ATP-synt_Z PF16594.5 EPE35851.1 - 0.065 12.7 0.8 0.12 11.8 0.8 1.5 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated HET PF06985.11 EPE35852.1 - 6.4e-11 42.8 12.0 3e-08 34.1 6.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ADH_N PF08240.12 EPE35853.1 - 1.6e-26 92.3 1.9 3.4e-26 91.3 1.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE35853.1 - 2e-08 34.2 0.0 5.3e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EPE35853.1 - 5.7e-06 26.2 0.9 1.5e-05 24.8 0.9 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated FANCL_C PF11793.8 EPE35853.1 - 0.051 13.7 0.3 0.095 12.9 0.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain OGFr_N PF04664.13 EPE35855.1 - 5e-18 65.4 0.0 6.8e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Cu-oxidase_2 PF07731.14 EPE35856.1 - 5.4e-24 84.5 0.6 2.1e-21 76.1 0.1 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EPE35856.1 - 3.2e-19 69.1 0.7 6.5e-19 68.1 0.1 1.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EPE35856.1 - 0.014 15.5 0.0 0.18 11.9 0.0 2.7 3 1 0 3 3 3 0 Multicopper oxidase Abhydrolase_6 PF12697.7 EPE35860.1 - 1e-12 49.2 0.0 1.3e-12 48.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EPE35860.1 - 0.086 11.7 0.0 0.33 9.8 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme Ank_4 PF13637.6 EPE35861.1 - 1.2e-12 48.1 0.0 0.0002 21.8 0.0 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE35861.1 - 1.1e-11 45.1 0.0 0.0094 16.5 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE35861.1 - 5.7e-09 36.1 0.1 4.5e-05 23.6 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE35861.1 - 3.8e-07 29.9 0.1 0.11 13.1 0.0 5.7 6 1 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 EPE35861.1 - 3.3e-06 27.3 0.0 0.62 10.6 0.0 5.1 4 1 0 4 4 4 1 Ankyrin repeat MFS_1 PF07690.16 EPE35862.1 - 2.3e-35 122.2 11.1 9.2e-21 74.2 0.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE35862.1 - 1.5e-06 27.3 11.9 1.9e-05 23.7 11.9 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 EPE35862.1 - 1.8e-05 23.5 24.7 0.0035 16.0 11.8 3.5 2 2 1 3 3 3 3 MFS/sugar transport protein OATP PF03137.20 EPE35862.1 - 4.7e-05 21.9 7.0 0.21 9.9 0.1 3.1 3 0 0 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EPE35862.1 - 9.8e-05 21.4 13.4 0.004 16.1 4.4 2.1 1 1 1 2 2 2 2 MFS_1 like family MFS_3 PF05977.13 EPE35862.1 - 0.021 13.2 12.5 0.025 13.0 2.1 2.5 3 0 0 3 3 3 0 Transmembrane secretion effector NAD_binding_6 PF08030.12 EPE35864.1 - 2.4e-17 63.5 0.0 3.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EPE35864.1 - 7e-17 61.7 15.3 7e-17 61.7 15.3 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EPE35864.1 - 3.5e-08 33.5 0.1 1.2e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 EPE35864.1 - 0.0062 17.2 0.0 0.13 12.9 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain LETM1 PF07766.13 EPE35865.1 - 1.5e-13 50.7 0.3 3.6e-12 46.2 0.2 2.2 2 0 0 2 2 2 2 LETM1-like protein RRM_1 PF00076.22 EPE35866.1 - 7.7e-11 41.7 0.0 1.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPE35866.1 - 5.8e-06 25.9 0.0 1.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EPE35866.1 - 0.03 14.4 0.0 0.074 13.1 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 DUF1290 PF06947.12 EPE35867.1 - 0.034 14.2 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1290) SANT_DAMP1_like PF16282.5 EPE35867.1 - 0.066 13.4 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Peptidase_U4 PF03419.13 EPE35868.1 - 0.016 14.5 7.9 0.019 14.3 7.9 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Chordopox_A13L PF05961.11 EPE35868.1 - 0.024 14.9 0.1 0.048 13.9 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein SET PF00856.28 EPE35869.1 - 5.8e-05 23.5 0.0 0.002 18.6 0.0 2.5 1 1 0 1 1 1 1 SET domain Fungal_trans PF04082.18 EPE35870.1 - 1e-08 34.6 0.1 2.3e-08 33.4 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 EPE35871.1 - 2e-83 279.0 47.0 2.7e-44 151.1 15.2 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EPE35871.1 - 1.5e-37 129.1 0.0 2.6e-17 63.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EPE35871.1 - 1.7e-25 88.8 4.9 8e-24 83.4 0.1 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 EPE35871.1 - 2e-15 56.7 33.9 8.3e-08 31.7 14.0 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 EPE35871.1 - 2e-05 24.5 0.0 0.099 12.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EPE35871.1 - 2.2e-05 24.1 0.5 0.0017 18.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.6 EPE35871.1 - 5.3e-05 23.7 0.0 0.0002 21.9 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EPE35871.1 - 0.00012 22.5 0.3 0.029 14.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EPE35871.1 - 0.00066 19.6 0.2 0.016 15.1 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EPE35871.1 - 0.0023 17.6 1.3 0.087 12.6 0.1 3.2 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EPE35871.1 - 0.012 15.9 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EPE35871.1 - 0.015 15.9 0.0 3.3 8.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EPE35871.1 - 0.05 13.0 0.0 0.39 10.1 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 EPE35871.1 - 0.082 12.5 1.2 1.7 8.2 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 EPE35871.1 - 0.085 13.1 0.3 0.9 9.8 0.2 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EPE35871.1 - 0.095 13.1 0.0 17 5.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EPE35871.1 - 0.13 12.4 0.0 0.85 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EPE35871.1 - 0.17 11.6 0.5 6.6 6.4 0.4 2.4 2 0 0 2 2 2 0 AAA domain Pyridoxal_deC PF00282.19 EPE35872.1 - 3.1e-76 256.5 0.0 5.1e-76 255.8 0.0 1.3 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EPE35872.1 - 6.2e-06 25.4 0.0 1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EPE35872.1 - 0.00041 19.7 0.0 0.00052 19.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase HTH_Tnp_Tc3_2 PF01498.18 EPE35873.1 - 0.28 11.4 4.7 0.32 11.3 1.1 2.2 2 0 0 2 2 2 0 Transposase AMMECR1 PF01871.17 EPE35875.1 - 1.1e-43 148.7 0.0 1.6e-43 148.2 0.0 1.4 1 1 0 1 1 1 1 AMMECR1 CytochromB561_N PF09786.9 EPE35875.1 - 0.075 12.0 5.8 0.093 11.7 5.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ras PF00071.22 EPE35876.1 - 3.9e-39 133.9 0.0 5.8e-38 130.0 0.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EPE35876.1 - 6.6e-11 42.5 0.0 1.9e-10 41.0 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE35876.1 - 0.002 17.6 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPE35876.1 - 0.0028 17.7 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NB-ARC PF00931.22 EPE35876.1 - 0.048 12.8 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Suf PF05843.14 EPE35877.1 - 2e-95 320.2 0.0 2e-95 320.2 0.0 4.0 4 0 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EPE35877.1 - 1.3e-05 25.6 1.3 0.0055 17.4 0.2 4.5 3 1 0 3 3 3 1 Tetratricopeptide repeat HAT PF02184.16 EPE35877.1 - 0.0012 18.8 0.2 0.17 11.9 0.2 2.5 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat Tex_N PF09371.10 EPE35877.1 - 0.039 13.6 0.6 0.077 12.7 0.6 1.4 1 0 0 1 1 1 0 Tex-like protein N-terminal domain TPR_16 PF13432.6 EPE35877.1 - 0.044 14.4 1.0 0.41 11.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EPE35877.1 - 0.069 13.7 0.0 14 6.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ASF1_hist_chap PF04729.13 EPE35878.1 - 1.6e-73 245.7 0.0 2.2e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone adh_short_C2 PF13561.6 EPE35879.1 - 6e-62 209.2 0.5 6.9e-62 209.0 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE35879.1 - 5.1e-42 143.5 0.7 6.2e-42 143.3 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE35879.1 - 4.3e-14 52.8 0.2 6.6e-14 52.2 0.2 1.2 1 0 0 1 1 1 1 KR domain LktC PF06261.11 EPE35879.1 - 0.23 11.4 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Pkinase_Tyr PF07714.17 EPE35880.1 - 0.16 11.2 0.0 0.79 8.9 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase Glyco_hydro_16 PF00722.21 EPE35882.1 - 2.6e-10 40.0 1.9 4.3e-10 39.3 1.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_tranf_2_3 PF13641.6 EPE35883.1 - 0.00024 21.1 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EPE35883.1 - 0.0018 18.1 0.1 0.0034 17.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EPE35883.1 - 0.069 12.6 0.0 0.21 11.1 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 21 VHS PF00790.19 EPE35884.1 - 4e-47 159.6 0.0 1.3e-46 157.9 0.0 1.8 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 EPE35884.1 - 2.9e-22 79.1 0.1 2.9e-22 79.1 0.1 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.14 EPE35884.1 - 7.5e-20 71.0 0.2 7.5e-20 71.0 0.2 2.6 4 0 0 4 4 4 1 GAT domain GGA_N-GAT PF18308.1 EPE35884.1 - 3.8e-07 29.6 0.3 1.3e-06 27.9 0.1 2.1 2 0 0 2 2 2 1 GGA N-GAT domain Ribo_biogen_C PF04034.13 EPE35885.1 - 5.2e-51 171.7 0.0 7.3e-51 171.2 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EPE35885.1 - 1.6e-12 47.1 1.1 1.6e-12 47.1 1.1 1.7 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI DTHCT PF08070.11 EPE35885.1 - 6.3 7.6 18.8 0.27 12.0 3.8 3.6 2 1 1 3 3 3 0 DTHCT (NUC029) region CDC45 PF02724.14 EPE35885.1 - 8.9 4.5 12.5 16 3.7 12.5 1.4 1 0 0 1 1 1 0 CDC45-like protein FAD_binding_4 PF01565.23 EPE35886.1 - 1.4e-23 83.2 1.6 2.3e-23 82.5 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE35886.1 - 0.00094 19.2 0.1 0.0024 18.0 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 EPE35887.1 - 1.1e-14 54.2 34.9 1.1e-14 54.2 34.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1129 PF06570.11 EPE35887.1 - 0.19 11.2 2.4 3.8 7.0 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) Sugar_tr PF00083.24 EPE35887.1 - 8.3 5.1 24.5 0.09 11.6 7.9 2.5 2 1 0 2 2 2 0 Sugar (and other) transporter Methyltransf_25 PF13649.6 EPE35888.1 - 7.4e-08 33.0 0.0 1.8e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE35888.1 - 3.2e-07 30.4 0.0 4.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE35888.1 - 9.9e-07 29.4 0.0 3.3e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 EPE35888.1 - 0.00053 19.5 0.0 0.19 11.2 0.0 2.4 1 1 1 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_31 PF13847.6 EPE35888.1 - 0.00075 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE35888.1 - 0.0029 18.2 0.0 0.0065 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EPE35888.1 - 0.065 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB Cellulase PF00150.18 EPE35889.1 - 6.8e-10 38.8 0.2 1.2e-09 38.0 0.2 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-RanBP PF00641.18 EPE35890.1 - 0.0068 15.7 2.7 0.0068 15.7 2.7 2.1 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others MFS_1 PF07690.16 EPE35892.1 - 6.4e-24 84.5 24.8 6.4e-24 84.5 24.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 EPE35893.1 - 3.2e-08 33.6 9.2 7.9e-08 32.3 9.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clostridium_P47 PF06597.11 EPE35893.1 - 0.061 12.1 0.2 1.1 7.9 0.0 2.0 2 0 0 2 2 2 0 Clostridium P-47 protein Lgl_C PF08596.10 EPE35895.1 - 6.4e-116 387.3 0.0 2.4e-115 385.4 0.0 1.9 3 0 0 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 EPE35895.1 - 1.5e-07 31.6 0.0 0.2 12.0 0.0 4.6 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPE35895.1 - 6.9e-05 23.6 3.0 1.8 9.5 0.1 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat WD40_like PF17005.5 EPE35895.1 - 0.0062 15.9 0.0 0.054 12.8 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain PP28 PF10252.9 EPE35897.1 - 3.6e-31 107.4 17.6 3.6e-31 107.4 17.6 3.0 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 PAS_9 PF13426.7 EPE35898.1 - 1.5e-21 76.6 0.0 2.9e-14 53.2 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 EPE35898.1 - 3.8e-16 59.1 0.0 3.2e-10 40.1 0.0 3.6 3 0 0 3 3 3 3 PAS fold GATA PF00320.27 EPE35898.1 - 2.1e-14 52.8 7.8 4.5e-14 51.8 7.8 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 EPE35898.1 - 1.7e-11 44.1 0.0 0.00035 20.5 0.0 3.7 3 1 0 3 3 3 3 PAS fold PAS_11 PF14598.6 EPE35898.1 - 6.5e-08 32.7 0.0 0.0059 16.7 0.0 3.0 3 1 0 3 3 3 2 PAS domain PAS_4 PF08448.10 EPE35898.1 - 6.1e-07 29.7 0.0 0.046 14.0 0.0 3.5 3 1 0 3 3 3 2 PAS fold PAS_2 PF08446.11 EPE35898.1 - 0.0049 17.5 0.0 0.47 11.1 0.0 2.8 2 0 0 2 2 2 1 PAS fold DMPK_coil PF08826.10 EPE35898.1 - 0.057 13.5 0.9 0.13 12.4 0.9 1.6 1 0 0 1 1 1 0 DMPK coiled coil domain like Importin_rep_4 PF18808.1 EPE35899.1 - 4.2e-34 116.7 9.7 1.4e-33 115.0 1.5 4.5 4 1 1 5 5 4 1 Importin repeat Importin_rep_5 PF18816.1 EPE35899.1 - 5.9e-23 80.9 3.1 7.5e-23 80.6 0.7 2.6 3 0 0 3 3 2 1 Importin repeat HEAT_EZ PF13513.6 EPE35899.1 - 8.7e-21 74.0 12.2 3.8e-11 43.3 0.4 8.1 7 1 2 9 9 7 3 HEAT-like repeat HEAT_2 PF13646.6 EPE35899.1 - 1.4e-16 60.6 12.6 9.5e-08 32.3 0.1 8.2 7 2 1 8 8 7 3 HEAT repeats HEAT PF02985.22 EPE35899.1 - 2.1e-16 58.6 12.1 0.026 14.8 0.0 10.1 12 0 0 12 12 9 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EPE35899.1 - 2.6e-12 47.1 0.1 0.018 15.6 0.0 6.2 3 2 4 7 7 6 3 Vacuolar 14 Fab1-binding region Importin_rep_6 PF18829.1 EPE35899.1 - 2.8e-12 46.7 1.6 6e-11 42.4 0.3 3.1 2 0 0 2 2 2 1 Importin repeat 6 RIX1 PF08167.12 EPE35899.1 - 1.5e-08 34.6 2.6 0.00016 21.5 0.1 4.9 5 1 1 6 6 5 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 EPE35899.1 - 4.9e-08 32.8 0.3 0.0026 17.3 0.1 4.0 3 1 1 4 4 4 2 CLASP N terminal MMS19_C PF12460.8 EPE35899.1 - 2.6e-07 30.1 0.5 2.6e-07 30.1 0.5 3.5 3 2 0 3 3 3 1 RNAPII transcription regulator C-terminal DRIM PF07539.12 EPE35899.1 - 6.5e-05 21.4 5.7 0.00025 19.5 0.5 3.6 2 2 1 3 3 3 1 Down-regulated in metastasis DUF3385 PF11865.8 EPE35899.1 - 0.00011 22.2 11.7 0.2 11.6 0.1 6.6 5 3 1 7 7 6 2 Domain of unknown function (DUF3385) TAN PF11640.8 EPE35899.1 - 0.00015 21.9 0.4 0.013 15.7 0.1 3.4 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair RTP1_C1 PF10363.9 EPE35899.1 - 0.00018 21.6 1.1 0.031 14.5 0.2 4.2 5 0 0 5 5 3 1 Required for nuclear transport of RNA pol II C-terminus 1 IBN_N PF03810.19 EPE35899.1 - 0.00043 20.1 1.6 0.0072 16.2 0.0 3.8 5 0 0 5 5 4 1 Importin-beta N-terminal domain MMS19_N PF14500.6 EPE35899.1 - 0.00069 19.3 2.9 0.21 11.1 0.3 3.9 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II Adaptin_N PF01602.20 EPE35899.1 - 0.00094 17.8 2.2 0.054 12.0 0.1 3.1 3 1 0 3 3 3 1 Adaptin N terminal region CAS_CSE1 PF03378.15 EPE35899.1 - 0.0017 17.0 4.1 2.7 6.4 0.0 4.3 3 1 2 5 5 5 2 CAS/CSE protein, C-terminus Arm PF00514.23 EPE35899.1 - 0.0023 17.9 12.7 0.033 14.3 0.1 5.2 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 EPE35899.1 - 0.0025 17.8 4.0 2.5 8.1 0.1 4.3 5 0 0 5 5 4 1 Myosin-binding striated muscle assembly central V-ATPase_H_N PF03224.14 EPE35899.1 - 0.0032 16.8 1.3 0.047 13.0 0.2 2.7 2 0 0 2 2 2 1 V-ATPase subunit H DNA_alkylation PF08713.11 EPE35899.1 - 0.0095 15.7 0.2 0.11 12.2 0.1 2.6 2 0 0 2 2 2 1 DNA alkylation repair enzyme DUF3535 PF12054.8 EPE35899.1 - 0.01 15.1 0.3 0.029 13.6 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) TFCD_C PF12612.8 EPE35899.1 - 0.018 14.9 0.1 6.6 6.5 0.1 4.3 5 0 0 5 5 5 0 Tubulin folding cofactor D C terminal Tti2 PF10521.9 EPE35899.1 - 0.08 12.5 0.1 6.3 6.2 0.0 3.4 2 1 0 2 2 2 0 Tti2 family DUF4042 PF13251.6 EPE35899.1 - 0.11 12.1 0.9 20 4.8 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4042) Telomere_reg-2 PF10193.9 EPE35899.1 - 0.3 11.6 8.0 0.87 10.1 1.9 3.9 3 1 1 4 4 4 0 Telomere length regulation protein CBS PF00571.28 EPE35900.1 - 2.2e-18 66.5 1.5 1.1e-05 25.8 0.0 4.4 4 0 0 4 4 4 4 CBS domain Glyco_hydro_76 PF03663.14 EPE35901.1 - 9.6e-160 532.0 19.2 1.1e-159 531.8 19.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EPE35901.1 - 0.0055 15.8 9.1 0.1 11.6 0.9 3.4 3 0 0 3 3 3 3 Glycosyl Hydrolase Family 88 Sacchrp_dh_C PF16653.5 EPE35902.1 - 1e-81 275.0 0.0 1.5e-81 274.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EPE35902.1 - 2.2e-24 86.2 0.9 3.3e-24 85.6 0.9 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EPE35902.1 - 8.3e-08 32.4 0.2 3.3e-07 30.4 0.0 1.8 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EPE35902.1 - 2.7e-05 24.1 0.4 4.7e-05 23.3 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EPE35903.1 - 5.5e-23 81.4 0.0 6e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPE35903.1 - 4.2e-12 46.1 0.0 1.3e-10 41.3 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE35903.1 - 5.6e-06 26.4 0.0 9.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EPE35903.1 - 0.0017 17.8 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EPE35903.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 EPE35905.1 - 6.8e-41 140.4 36.5 1.8e-40 139.0 31.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE35905.1 - 3.9e-07 29.3 27.1 1.2e-05 24.4 27.1 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EPE35905.1 - 3.2e-06 25.9 3.1 4.8e-06 25.3 3.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GFA PF04828.14 EPE35906.1 - 9.1e-24 83.6 1.9 1.1e-10 41.6 0.0 2.7 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.11 EPE35906.1 - 0.00067 19.8 3.8 0.023 14.9 1.3 3.0 2 1 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like DUF2321 PF10083.9 EPE35906.1 - 0.073 12.7 0.2 3.9 7.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) NapB PF03892.14 EPE35906.1 - 0.19 11.7 1.6 0.36 10.8 1.6 1.4 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Nudix_N_2 PF14803.6 EPE35906.1 - 1.6 8.7 0.0 1.6 8.7 0.0 3.9 5 0 0 5 5 5 0 Nudix N-terminal ubiquitin PF00240.23 EPE35907.1 - 3.4e-08 33.1 0.1 6e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S2 PF00318.20 EPE35908.1 - 2.9e-68 229.3 0.0 1.5e-67 227.0 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S2 CBS PF00571.28 EPE35909.1 - 4.4e-35 119.9 8.4 3.5e-09 37.0 0.0 5.6 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 EPE35909.1 - 8.2e-09 35.3 0.0 3.4e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 PB1 domain zf-C2H2 PF00096.26 EPE35910.1 - 3.9e-06 27.0 22.6 0.00039 20.7 7.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPE35910.1 - 6.4e-06 26.4 13.8 0.0028 18.0 2.3 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPE35910.1 - 1.6e-05 25.3 21.0 0.011 16.5 6.6 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EPE35910.1 - 0.14 12.0 11.5 0.67 9.8 4.5 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type AT_hook PF02178.19 EPE35910.1 - 1.9 8.6 5.5 5.4 7.2 5.5 1.8 1 0 0 1 1 1 0 AT hook motif DAO PF01266.24 EPE35913.1 - 3.3e-51 174.9 0.0 5.1e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EPE35913.1 - 3e-44 149.9 0.0 5.5e-44 149.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EPE35913.1 - 3.2e-08 33.1 0.2 7.6e-08 31.8 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EPE35913.1 - 3.6e-05 23.3 0.6 7.9e-05 22.2 0.4 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE35913.1 - 0.00015 21.1 0.0 0.00028 20.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EPE35913.1 - 0.0036 16.4 0.0 0.014 14.5 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EPE35913.1 - 0.02 15.1 0.3 0.085 13.1 0.2 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EPE35913.1 - 0.04 14.5 0.1 0.12 12.9 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EPE35913.1 - 0.042 13.7 0.3 0.083 12.8 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EPE35913.1 - 0.046 12.4 0.4 0.073 11.8 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EPE35913.1 - 0.088 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 EPE35914.1 - 3.4e-25 88.6 0.0 6.1e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE35914.1 - 4.1e-07 30.0 6.7 7.8e-07 29.1 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 EPE35916.1 - 7.4e-73 245.3 0.0 8.4e-73 245.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ntox47 PF15540.6 EPE35916.1 - 0.18 12.1 0.6 0.5 10.7 0.2 1.9 2 0 0 2 2 2 0 Bacterial toxin 47 adh_short PF00106.25 EPE35917.1 - 3.8e-14 52.6 0.0 4.6e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE35917.1 - 5.7e-10 39.1 0.0 7.5e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE35917.1 - 6.4e-05 22.9 0.0 8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Mucin PF01456.17 EPE35918.1 - 0.026 14.5 9.6 0.03 14.3 9.6 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein AIDA PF16168.5 EPE35918.1 - 0.039 14.0 2.3 0.082 13.0 2.3 1.5 1 1 0 1 1 1 0 Adhesin of bacterial autotransporter system, probable stalk MFS_1 PF07690.16 EPE35921.1 - 1.9e-43 148.8 35.1 1.9e-43 148.8 35.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE35921.1 - 1.7e-16 60.2 20.1 1.6e-15 56.9 20.0 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EPE35921.1 - 1.1e-07 30.7 5.4 1.1e-07 30.7 5.4 1.5 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) YjbE PF11106.8 EPE35921.1 - 7.8 6.8 7.4 0.78 10.0 2.0 2.1 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE SLAC1 PF03595.17 EPE35923.1 - 8.3e-78 261.9 40.3 1.1e-77 261.5 40.3 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF5056 PF16479.5 EPE35923.1 - 0.18 12.0 2.2 0.69 10.2 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) DUF3325 PF11804.8 EPE35923.1 - 0.33 11.1 4.4 11 6.3 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) SOG2 PF10428.9 EPE35924.1 - 1e-70 239.4 2.8 8.5e-48 163.8 0.0 4.4 4 1 1 5 5 5 2 RAM signalling pathway protein LRR_8 PF13855.6 EPE35924.1 - 8.9e-17 60.6 3.3 3.1e-10 39.7 0.4 2.6 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EPE35924.1 - 4.6e-16 58.7 4.5 3.4e-06 27.3 0.8 4.0 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EPE35924.1 - 0.00051 19.9 4.5 9.6 6.5 0.1 5.2 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 EPE35924.1 - 0.0093 16.4 9.6 22 6.1 0.1 5.4 5 0 0 5 5 5 2 Leucine Rich Repeat ING PF12998.7 EPE35924.1 - 0.22 12.1 1.4 14 6.3 0.2 2.8 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Actin PF00022.19 EPE35925.1 - 1.9e-127 425.3 0.0 8.5e-127 423.1 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EPE35925.1 - 0.011 14.6 0.0 0.072 11.9 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein baeRF_family10 PF18854.1 EPE35925.1 - 0.041 14.1 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 ApbA_C PF08546.11 EPE35926.1 - 4.6e-27 94.7 0.0 1e-26 93.5 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EPE35926.1 - 1.9e-26 92.5 0.0 2.5e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 EPE35926.1 - 0.052 12.9 1.1 0.087 12.2 1.1 1.3 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.20 EPE35926.1 - 0.074 13.1 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MPLKIP PF15502.6 EPE35926.1 - 0.22 11.8 0.1 0.39 11.0 0.1 1.4 1 0 0 1 1 1 0 M-phase-specific PLK1-interacting protein Cu-binding_MopE PF11617.8 EPE35927.1 - 0.037 14.2 2.3 1 9.6 0.5 2.5 2 0 0 2 2 2 0 Putative metal-binding motif XH PF03469.14 EPE35928.1 - 0.0018 18.2 0.1 0.0032 17.4 0.1 1.3 1 0 0 1 1 1 1 XH domain Pyr_redox_2 PF07992.14 EPE35930.1 - 3e-62 210.5 0.9 3.9e-62 210.1 0.9 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EPE35930.1 - 2.4e-33 114.7 0.6 2.4e-32 111.5 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EPE35930.1 - 1.9e-19 70.0 0.6 2.1e-18 66.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE35930.1 - 3.3e-12 46.3 4.1 2.1e-11 43.6 4.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPE35930.1 - 6e-08 32.2 0.0 1.6e-06 27.5 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 EPE35930.1 - 0.0031 16.8 0.5 2 7.7 0.2 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EPE35930.1 - 0.0034 16.2 3.9 0.62 8.7 0.0 3.1 2 1 0 3 3 3 2 HI0933-like protein 2-Hacid_dh_C PF02826.19 EPE35930.1 - 0.01 15.2 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EPE35930.1 - 0.02 14.3 0.1 0.043 13.2 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Eno-Rase_NADH_b PF12242.8 EPE35930.1 - 0.033 14.0 0.4 0.48 10.2 0.3 2.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_binding_2 PF00890.24 EPE35930.1 - 0.046 12.8 2.5 0.36 9.8 0.8 2.6 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.18 EPE35930.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pro-kuma_activ PF09286.11 EPE35931.1 - 2.5e-39 134.8 1.6 4.5e-39 134.0 1.6 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EPE35931.1 - 4.2e-06 26.2 0.3 8.1e-06 25.3 0.1 1.5 2 0 0 2 2 2 1 Subtilase family Peptidase_S8 PF00082.22 EPE35932.1 - 3.1e-31 108.7 3.9 5.2e-31 108.0 3.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EPE35932.1 - 5.3e-09 36.6 0.0 1e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Tcp11 PF05794.13 EPE35933.1 - 9.1e-104 348.0 0.4 9.1e-104 348.0 0.4 2.6 3 0 0 3 3 3 1 T-complex protein 11 DUF3510 PF12022.8 EPE35933.1 - 0.032 14.6 3.8 0.055 13.9 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) DUF5081 PF16887.5 EPE35933.1 - 0.11 11.6 0.1 0.3 10.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5081) DUF1871 PF08958.10 EPE35933.1 - 0.17 12.2 0.0 14 6.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1871) IFRD PF05004.13 EPE35934.1 - 1e-87 294.1 7.0 1.3e-87 293.8 7.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) DUF4618 PF15397.6 EPE35934.1 - 1.1 8.7 5.3 12 5.2 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4618) FHA PF00498.26 EPE35935.1 - 9.6e-14 51.5 0.0 2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EPE35935.1 - 0.00013 22.3 0.0 0.00032 21.0 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF3602 PF12223.8 EPE35938.1 - 7.6e-20 71.3 13.3 2.7e-18 66.4 2.2 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) PNPase_C PF12111.8 EPE35938.1 - 6.1 6.4 11.4 2.3 7.7 0.9 3.4 3 0 0 3 3 3 0 Polyribonucleotide phosphorylase C terminal RRM_1 PF00076.22 EPE35944.1 - 3.1e-13 49.3 0.0 9.1e-13 47.8 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EPE35944.1 - 0.016 15.2 0.1 0.036 14.1 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SMN PF06003.12 EPE35945.1 - 3.7 6.7 11.3 2.4 7.4 0.1 2.9 2 1 0 3 3 3 0 Survival motor neuron protein (SMN) Cu_bind_like PF02298.17 EPE35947.1 - 0.0045 17.0 0.1 0.018 15.1 0.1 1.8 1 1 0 1 1 1 1 Plastocyanin-like domain 4F5 PF04419.14 EPE35948.1 - 3.1e-08 34.4 9.2 3.1e-08 34.4 9.2 2.1 3 0 0 3 3 3 1 4F5 protein family Neurensin PF14927.6 EPE35949.1 - 0.34 10.6 1.5 0.53 10.0 0.1 2.0 2 0 0 2 2 2 0 Neurensin Caps_synth_CapC PF14102.6 EPE35949.1 - 1 9.8 7.3 0.063 13.7 2.1 1.6 2 0 0 2 2 2 0 Capsule biosynthesis CapC Guanylate_kin PF00625.21 EPE35950.1 - 2.7e-54 183.6 0.0 3.1e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 EPE35950.1 - 9.9e-06 25.6 0.0 1.6e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EPE35950.1 - 0.0002 21.9 1.0 0.0016 19.0 1.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EPE35950.1 - 0.00026 21.2 0.1 0.0074 16.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPE35950.1 - 0.0014 19.0 0.2 0.014 15.7 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPE35950.1 - 0.005 17.1 0.0 0.013 15.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 EPE35950.1 - 0.0086 15.9 0.3 0.39 10.6 0.0 2.5 1 1 1 2 2 2 1 Deoxynucleoside kinase AAA_24 PF13479.6 EPE35950.1 - 0.01 15.6 0.1 3.3 7.4 0.0 2.3 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EPE35950.1 - 0.023 14.9 0.0 0.1 12.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EPE35950.1 - 0.028 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 EPE35950.1 - 0.042 13.8 1.2 0.73 9.7 1.2 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 EPE35950.1 - 0.22 12.0 0.9 1 9.8 0.0 2.1 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 EPE35951.1 - 8e-112 373.1 0.3 9.5e-112 372.9 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EPE35951.1 - 6.7e-08 32.6 0.0 1.2e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EPE35951.1 - 4.4e-06 26.2 0.0 7.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EPE35951.1 - 3.2e-05 23.9 0.1 0.00026 20.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EPE35951.1 - 0.00022 20.8 0.6 0.012 15.2 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EPE35951.1 - 0.00046 20.3 0.3 1.4 8.9 0.0 2.5 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 EPE35951.1 - 0.0033 17.8 0.1 0.012 16.0 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EPE35951.1 - 0.0078 15.4 0.1 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 EPE35951.1 - 0.0086 16.3 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EPE35951.1 - 0.0089 15.6 0.2 0.049 13.1 0.1 2.2 1 1 1 2 2 2 1 P-loop containing dynein motor region ABC_tran PF00005.27 EPE35951.1 - 0.012 16.1 0.2 0.02 15.4 0.2 1.6 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 EPE35951.1 - 0.024 13.8 0.4 0.071 12.2 0.4 1.9 1 1 0 1 1 1 0 G-protein alpha subunit Gtr1_RagA PF04670.12 EPE35951.1 - 0.046 13.1 0.1 0.5 9.7 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 EPE35951.1 - 0.072 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 EPE35951.1 - 0.085 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EPE35951.1 - 0.087 13.3 0.1 0.2 12.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EPE35951.1 - 0.12 11.4 0.0 0.26 10.3 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 EPE35951.1 - 0.19 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.32 EPE35952.1 - 1.8e-22 79.2 7.5 6.8e-08 33.1 1.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Ribosomal_L32p PF01783.23 EPE35952.1 - 8.4e-14 51.6 2.2 1.8e-13 50.5 2.2 1.6 1 0 0 1 1 1 1 Ribosomal L32p protein family ANAPC4_WD40 PF12894.7 EPE35952.1 - 1.5e-13 50.8 1.7 0.0074 16.6 0.0 4.5 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE35952.1 - 7.5e-05 22.7 0.3 0.026 14.4 0.0 3.5 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EPE35952.1 - 0.0025 16.4 0.1 0.023 13.2 0.1 1.9 1 1 1 2 2 2 1 Cytochrome D1 heme domain RecR PF02132.15 EPE35952.1 - 0.0031 17.0 0.6 0.0073 15.9 0.6 1.6 1 0 0 1 1 1 1 RecR protein Nbas_N PF15492.6 EPE35952.1 - 0.0042 16.5 0.4 0.59 9.4 0.0 3.2 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 EPE35952.1 - 0.013 14.5 0.5 8.2 5.3 0.0 3.5 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EPE35952.1 - 0.015 14.6 0.0 4.4 6.5 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 EPE35952.1 - 0.026 13.2 0.2 0.32 9.6 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EPE35952.1 - 0.048 12.6 0.5 0.2 10.6 0.2 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Coatomer_WDAD PF04053.14 EPE35952.1 - 0.058 12.4 0.0 0.19 10.7 0.0 1.6 1 1 0 1 1 1 0 Coatomer WD associated region RimM PF01782.18 EPE35952.1 - 0.082 13.1 0.1 0.25 11.6 0.1 1.9 1 0 0 1 1 1 0 RimM N-terminal domain DUF1513 PF07433.11 EPE35952.1 - 0.11 11.6 0.4 1.4 8.0 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) MID_MedPIWI PF18296.1 EPE35953.1 - 0.15 11.9 5.7 0.19 11.5 5.7 1.2 1 0 0 1 1 1 0 MID domain of medPIWI DUF908 PF06012.12 EPE35953.1 - 0.15 11.5 6.4 0.16 11.4 6.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF1180 PF06679.12 EPE35953.1 - 1.1 9.6 9.0 1.7 9.0 9.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DHHW PF14286.6 EPE35953.1 - 1.8 7.8 5.9 2.3 7.5 5.9 1.1 1 0 0 1 1 1 0 DHHW protein Kei1 PF08552.11 EPE35953.1 - 5.9 6.7 8.7 9.9 6.0 8.7 1.6 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Ydc2-catalyt PF09159.10 EPE35954.1 - 4.9e-76 256.1 0.1 6.3e-76 255.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 EPE35954.1 - 1e-07 32.2 0.1 0.0029 17.7 0.0 3.2 2 1 0 2 2 2 2 Poxvirus A22 protein SAP PF02037.27 EPE35954.1 - 2.8e-06 26.9 1.8 3.4e-06 26.7 0.2 2.1 2 0 0 2 2 2 1 SAP domain Tissue_fac PF01108.17 EPE35954.1 - 0.0038 17.0 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 Tissue factor CFEM PF05730.11 EPE35955.1 - 6.1e-10 39.1 12.4 6.6e-10 38.9 10.2 2.0 2 0 0 2 2 2 1 CFEM domain Aa_trans PF01490.18 EPE35956.1 - 4.3e-72 243.1 33.7 5.2e-72 242.8 33.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YrhC PF14143.6 EPE35956.1 - 7.1 6.8 7.7 1.1 9.4 0.2 3.0 3 1 0 3 3 3 0 YrhC-like protein Ras PF00071.22 EPE35959.1 - 1.2e-55 187.6 0.0 1.4e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE35959.1 - 9e-22 77.5 0.0 1.4e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE35959.1 - 5.4e-07 29.2 0.0 8.8e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EPE35959.1 - 0.0021 17.5 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit baeRF_family3 PF18845.1 EPE35959.1 - 0.083 13.1 0.0 0.42 10.9 0.0 1.8 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 NB-ARC PF00931.22 EPE35959.1 - 0.091 11.9 0.1 0.84 8.8 0.0 2.1 1 1 1 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 EPE35959.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region KOW PF00467.29 EPE35960.1 - 2.8e-07 30.2 3.0 7.7e-07 28.9 3.0 1.8 1 0 0 1 1 1 1 KOW motif ExsD PF16806.5 EPE35960.1 - 0.013 15.5 0.2 0.02 14.8 0.2 1.3 1 0 0 1 1 1 0 Antiactivator protein ExsD IKI3 PF04762.12 EPE35961.1 - 0 1062.2 0.0 0 1061.9 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 EPE35961.1 - 5.9e-06 26.5 1.1 2.9 8.2 0.0 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF3984 PF13136.6 EPE35962.1 - 1.2e-52 179.4 22.9 1.9e-50 172.1 22.9 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) TPR_12 PF13424.6 EPE35963.1 - 2.4e-58 194.4 16.9 8.7e-17 61.2 0.2 5.6 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 EPE35963.1 - 7.2e-55 181.5 12.7 1.3e-08 34.4 0.1 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 EPE35963.1 - 7.9e-30 101.4 17.2 0.00039 20.1 0.3 7.8 7 1 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 EPE35963.1 - 1.7e-29 99.6 9.7 0.00014 21.7 0.0 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.6 EPE35963.1 - 8.1e-26 88.1 11.6 0.002 18.2 0.2 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 EPE35963.1 - 4.6e-24 82.6 17.0 0.0025 17.8 0.1 8.2 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_MalT PF17874.1 EPE35963.1 - 8.1e-19 68.2 0.1 8.6e-07 28.6 0.0 3.2 1 1 1 3 3 3 3 MalT-like TPR region TPR_14 PF13428.6 EPE35963.1 - 1.6e-16 59.6 10.0 0.016 16.0 0.1 7.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EPE35963.1 - 1.4e-13 51.3 18.0 0.018 15.7 0.4 6.8 5 1 1 6 6 6 5 Tetratricopeptide repeat HET PF06985.11 EPE35963.1 - 3.6e-11 43.6 4.1 1.7e-08 34.9 0.1 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_4 PF07721.14 EPE35963.1 - 8.2e-10 38.4 0.0 1 10.2 0.0 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat NB-ARC PF00931.22 EPE35963.1 - 5.7e-08 32.3 0.0 4.1e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 NB-ARC domain TPR_6 PF13174.6 EPE35963.1 - 7.5e-08 32.5 16.1 1.2 9.9 0.4 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EPE35963.1 - 1.5e-07 31.8 14.3 0.027 15.0 0.7 6.0 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EPE35963.1 - 1.8e-07 31.0 12.0 1.7 9.2 0.1 7.8 7 0 0 7 7 7 2 Tetratricopeptide repeat AAA_16 PF13191.6 EPE35963.1 - 3.4e-05 24.3 0.0 0.00011 22.6 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain PPR PF01535.20 EPE35963.1 - 4.5e-05 23.4 5.9 0.97 9.8 0.0 6.6 7 0 0 7 7 7 1 PPR repeat ATPase_2 PF01637.18 EPE35963.1 - 8.2e-05 22.6 0.1 0.00019 21.4 0.1 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_11 PF13414.6 EPE35963.1 - 0.00031 20.4 10.2 24 4.7 0.0 6.9 7 0 0 7 7 7 0 TPR repeat Tcf25 PF04910.14 EPE35963.1 - 0.00047 19.4 0.1 10 5.1 0.0 4.0 4 0 0 4 4 4 0 Transcriptional repressor TCF25 SNAP PF14938.6 EPE35963.1 - 0.00071 19.1 1.4 0.57 9.6 0.1 3.2 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP DUF2225 PF09986.9 EPE35963.1 - 0.0069 16.1 5.2 15 5.3 0.4 4.1 2 1 2 5 5 4 0 Uncharacterized protein conserved in bacteria (DUF2225) NACHT PF05729.12 EPE35963.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain SPO22 PF08631.10 EPE35963.1 - 0.028 13.9 0.0 1.2 8.6 0.0 3.1 1 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like Wzy_C_2 PF11846.8 EPE35963.1 - 0.055 13.4 0.2 4.7 7.1 0.0 3.3 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal RPN7 PF10602.9 EPE35963.1 - 0.2 11.4 4.0 9.7 5.9 0.4 3.7 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 EPE35963.1 - 0.59 9.8 12.2 15 5.3 0.1 5.1 2 1 1 4 4 4 0 Tetratricopeptide repeat-like domain Asp PF00026.23 EPE35964.1 - 1.4e-65 221.8 3.3 3.4e-65 220.5 3.3 1.6 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPE35964.1 - 1.4e-07 32.0 2.5 2.9e-06 27.6 0.1 3.7 2 2 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EPE35964.1 - 0.036 13.9 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal DUF1979 PF09322.10 EPE35964.1 - 0.12 12.3 0.5 0.56 10.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) Asp_protease_2 PF13650.6 EPE35964.1 - 2.3 8.9 5.4 4.9 7.9 0.1 3.7 3 1 0 3 3 3 0 Aspartyl protease F-box PF00646.33 EPE35965.1 - 1.6e-06 27.8 0.1 4.3e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPE35965.1 - 0.00011 22.0 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EPE35965.1 - 0.0013 18.6 2.5 0.0013 18.6 0.0 2.2 3 0 0 3 3 3 1 F-box PRANC PF09372.10 EPE35965.1 - 0.16 12.3 0.2 0.58 10.5 0.1 2.0 2 0 0 2 2 2 0 PRANC domain Kelch_5 PF13854.6 EPE35966.1 - 0.13 12.3 0.1 0.13 12.3 0.1 4.1 5 1 0 5 5 5 0 Kelch motif Kelch_6 PF13964.6 EPE35966.1 - 0.26 11.7 8.1 60 4.1 0.0 5.4 6 0 0 6 6 6 0 Kelch motif Oxidored_q5_N PF01059.17 EPE35967.1 - 0.053 13.6 3.5 0.067 13.3 0.1 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus HhH-GPD PF00730.25 EPE35968.1 - 3.3e-15 56.5 0.0 6e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Anp1 PF03452.14 EPE35969.1 - 5e-111 370.3 0.0 6.2e-111 370.0 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 EPE35969.1 - 0.021 14.7 0.1 0.18 11.6 0.1 2.2 2 1 0 2 2 2 0 Glycosyl transferase family 2 UCR_14kD PF02271.16 EPE35970.1 - 1.9e-42 143.3 0.3 2.2e-42 143.1 0.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 EPE35971.1 - 3.4e-65 216.0 4.9 3.1e-23 81.5 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Arabinose_trans PF04602.12 EPE35972.1 - 6.5e-05 21.9 0.0 7.6e-05 21.7 0.0 1.0 1 0 0 1 1 1 1 Mycobacterial cell wall arabinan synthesis protein ABC1 PF03109.16 EPE35973.1 - 2.2e-32 111.7 0.0 4e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family tRNA-synt_His PF13393.6 EPE35974.1 - 3.2e-38 131.8 0.0 3.1e-37 128.5 0.0 2.0 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EPE35974.1 - 7.8e-09 35.6 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.20 EPE35974.1 - 0.0022 17.1 0.0 0.022 13.9 0.0 2.1 1 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Pkinase PF00069.25 EPE35977.1 - 9e-07 28.5 0.0 1.9e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Mon1 PF03164.14 EPE35977.1 - 0.042 12.9 0.0 0.19 10.7 0.0 2.1 3 0 0 3 3 3 0 Trafficking protein Mon1 Pkinase_Tyr PF07714.17 EPE35977.1 - 0.15 11.3 0.0 0.47 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.25 EPE35978.1 - 2.6e-71 240.1 0.0 1.2e-70 237.9 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE35978.1 - 3.7e-47 160.8 0.0 6.2e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPE35978.1 - 0.00039 19.3 0.0 0.00071 18.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EPE35978.1 - 0.0028 17.0 0.0 0.0081 15.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like V-ATPase_H_N PF03224.14 EPE35978.1 - 0.041 13.2 0.7 3.2 7.0 0.0 2.5 2 0 0 2 2 2 0 V-ATPase subunit H CLASP_N PF12348.8 EPE35978.1 - 0.16 11.5 2.1 0.29 10.7 0.3 2.1 2 0 0 2 2 2 0 CLASP N terminal Mur_ligase_M PF08245.12 EPE35980.1 - 2.1e-05 24.6 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain SPATIAL PF15256.6 EPE35980.1 - 0.026 14.9 0.1 0.046 14.1 0.1 1.4 1 0 0 1 1 1 0 SPATIAL PRK PF00485.18 EPE35982.1 - 0.00035 20.4 0.0 0.00065 19.5 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 EPE35982.1 - 0.0013 18.0 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 EPE35982.1 - 0.008 16.4 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPE35982.1 - 0.012 16.0 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EPE35982.1 - 0.012 16.1 0.1 0.027 15.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EPE35982.1 - 0.017 14.4 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 EPE35982.1 - 0.02 14.0 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 EPE35982.1 - 0.02 14.1 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EPE35982.1 - 0.043 13.7 0.3 0.071 13.0 0.3 1.3 1 0 0 1 1 1 0 NTPase MeaB PF03308.16 EPE35982.1 - 0.071 12.1 0.4 2 7.3 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 EPE35982.1 - 0.077 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 EPE35982.1 - 0.094 13.1 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EPE35982.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EPE35982.1 - 0.11 12.6 0.3 0.2 11.8 0.3 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EPE35982.1 - 0.12 12.3 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 EPE35982.1 - 0.17 11.5 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 EPE35982.1 - 0.2 11.1 0.1 0.31 10.5 0.1 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 cobW PF02492.19 EPE35982.1 - 0.2 11.2 0.7 0.3 10.7 0.7 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 EPE35982.1 - 0.21 12.0 0.0 0.47 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRELI PF04707.14 EPE35983.1 - 6e-42 143.1 0.6 7.3e-42 142.9 0.6 1.1 1 0 0 1 1 1 1 PRELI-like family Rpn3_C PF08375.11 EPE35984.1 - 7.3e-27 93.6 1.7 2.4e-26 91.9 1.7 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EPE35984.1 - 1.3e-20 73.9 0.4 1.4e-19 70.5 0.1 2.6 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 EPE35984.1 - 0.01 15.9 0.2 0.031 14.4 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat MOZ_SAS PF01853.18 EPE35985.1 - 4e-35 121.1 0.0 3e-33 115.0 0.0 2.4 1 1 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EPE35985.1 - 1.1e-08 34.5 0.0 2.3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_1 PF00583.25 EPE35985.1 - 0.056 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE35985.1 - 0.15 12.5 0.0 0.55 10.7 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF4748 PF15932.5 EPE35985.1 - 7.4 6.4 5.8 28 4.6 5.8 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) NOA36 PF06524.12 EPE35987.1 - 9.9 5.4 17.2 0.18 11.1 4.2 2.1 2 0 0 2 2 2 0 NOA36 protein Zn_clus PF00172.18 EPE35988.1 - 2.9e-06 27.3 4.7 7.9e-06 25.9 4.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC45 PF02724.14 EPE35988.1 - 0.064 11.6 4.6 0.08 11.2 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Zn_clus PF00172.18 EPE35989.1 - 0.0043 17.1 11.5 0.0093 16.1 11.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HpcH_HpaI PF03328.14 EPE35990.1 - 3.8e-20 72.0 0.0 4.6e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family AT_hook PF02178.19 EPE35991.1 - 3.5 7.8 11.4 0.28 11.2 5.4 2.6 2 0 0 2 2 2 0 AT hook motif Amidohydro_1 PF01979.20 EPE35992.1 - 2.1e-24 86.5 0.0 1.6e-23 83.6 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPE35992.1 - 3.1e-12 46.7 0.4 7.2e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family PHD PF00628.29 EPE35993.1 - 7.3e-07 29.0 6.3 1.4e-06 28.0 6.3 1.5 1 0 0 1 1 1 1 PHD-finger ATG16 PF08614.11 EPE35993.1 - 3.6e-06 27.3 9.9 6.8e-06 26.5 9.7 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) PHD_2 PF13831.6 EPE35993.1 - 0.00019 20.9 1.8 0.00038 19.9 1.8 1.5 1 0 0 1 1 1 1 PHD-finger HOOK PF05622.12 EPE35993.1 - 0.0002 19.7 8.1 0.00028 19.2 8.1 1.1 1 0 0 1 1 1 1 HOOK protein CENP-F_leu_zip PF10473.9 EPE35993.1 - 0.0025 17.9 16.1 0.021 14.8 15.7 2.0 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 C1_1 PF00130.22 EPE35993.1 - 0.0038 17.1 3.0 0.0038 17.1 3.0 2.0 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) ATP-synt_D PF01813.17 EPE35993.1 - 0.0094 15.8 5.2 0.099 12.5 2.7 2.1 2 0 0 2 2 2 1 ATP synthase subunit D zf-HC5HC2H PF13771.6 EPE35993.1 - 0.019 15.2 1.7 0.04 14.2 1.7 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Zf_RING PF16744.5 EPE35993.1 - 0.026 14.6 1.0 0.06 13.5 1.0 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger DUF4407 PF14362.6 EPE35993.1 - 0.026 13.9 2.2 0.039 13.3 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-HC5HC2H_2 PF13832.6 EPE35993.1 - 0.058 13.6 0.2 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain APG6_N PF17675.1 EPE35993.1 - 0.061 13.8 10.3 0.12 12.9 10.1 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region zf-PHD-like PF15446.6 EPE35993.1 - 0.074 12.7 2.0 0.16 11.6 2.0 1.6 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain ZapB PF06005.12 EPE35993.1 - 0.13 12.7 12.2 6.3 7.3 12.2 2.3 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 EPE35993.1 - 0.18 11.6 7.8 0.62 9.9 2.6 2.4 1 1 1 2 2 2 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 EPE35993.1 - 0.3 11.3 11.7 0.45 10.7 11.4 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Tropomyosin_1 PF12718.7 EPE35993.1 - 0.58 10.3 12.8 4.6 7.4 12.8 2.1 1 1 0 1 1 1 0 Tropomyosin like DASH_Spc19 PF08287.11 EPE35993.1 - 0.6 10.0 10.1 0.99 9.3 10.1 1.3 1 0 0 1 1 1 0 Spc19 FlaC_arch PF05377.11 EPE35993.1 - 1.1 9.8 11.4 0.23 11.9 2.9 2.8 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) CortBP2 PF09727.9 EPE35993.1 - 2.4 8.0 14.0 12 5.8 14.1 1.9 1 1 0 1 1 1 0 Cortactin-binding protein-2 DUF2570 PF10828.8 EPE35993.1 - 2.8 7.8 4.3 0.85 9.5 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) CENP-H PF05837.12 EPE35993.1 - 3.2 8.2 11.6 7.1 7.1 11.5 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Rx_N PF18052.1 EPE35993.1 - 3.3 8.0 7.9 33 4.8 7.5 2.5 1 1 0 1 1 1 0 Rx N-terminal domain Spc24 PF08286.11 EPE35993.1 - 3.9 7.8 7.0 8.8 6.6 0.1 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.8 EPE35993.1 - 4.1 7.5 13.7 12 6.0 7.3 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TPD52 PF04201.15 EPE35993.1 - 4.3 6.9 9.6 7.4 6.2 5.0 2.3 1 1 1 2 2 2 0 Tumour protein D52 family Prefoldin_2 PF01920.20 EPE35993.1 - 5.2 7.1 10.6 1.1e+03 -0.4 10.4 2.8 1 1 0 1 1 1 0 Prefoldin subunit BRE1 PF08647.11 EPE35993.1 - 5.2 7.2 9.7 12 6.1 9.7 1.6 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase CENP-Q PF13094.6 EPE35993.1 - 5.6 7.1 12.6 7.9 6.7 11.7 1.7 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Cnn_1N PF07989.11 EPE35993.1 - 6.2 7.1 10.2 11 6.2 0.3 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Csm1_N PF18504.1 EPE35993.1 - 6.7 7.1 10.5 2.3 8.6 4.8 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain TMF_TATA_bd PF12325.8 EPE35993.1 - 7.4 6.8 15.4 6 7.1 5.5 2.5 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding Mucin PF01456.17 EPE35994.1 - 0.33 10.9 7.1 0.54 10.2 7.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein THOC7 PF05615.13 EPE35995.1 - 0.0019 18.5 1.4 0.0019 18.5 1.4 2.6 3 0 0 3 3 3 1 Tho complex subunit 7 Pil1 PF13805.6 EPE35995.1 - 0.0027 17.2 1.5 0.078 12.4 0.4 2.3 2 0 0 2 2 2 1 Eisosome component PIL1 TPR_MLP1_2 PF07926.12 EPE35995.1 - 0.031 14.3 7.4 0.91 9.6 1.9 3.0 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein MtrG PF04210.13 EPE35995.1 - 0.095 12.6 0.4 0.71 9.8 0.0 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Erp_C PF06780.11 EPE35995.1 - 0.41 10.6 4.5 1.1 9.2 0.0 2.9 3 1 0 3 3 3 0 Erp protein C-terminus FlaC_arch PF05377.11 EPE35995.1 - 1.1 9.7 6.1 1.5 9.3 0.3 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) FliT PF05400.13 EPE35995.1 - 7 7.5 6.8 3 8.7 3.7 2.0 2 0 0 2 2 2 0 Flagellar protein FliT PIP5K PF01504.18 EPE35996.1 - 1.6e-100 335.8 0.2 3.6e-100 334.7 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase WSC PF01822.19 EPE35997.1 - 2.3e-37 127.0 25.7 1.8e-19 69.7 7.5 2.1 2 0 0 2 2 2 2 WSC domain NAD_binding_6 PF08030.12 EPE35998.1 - 6.9e-32 110.7 0.0 1.8e-31 109.4 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EPE35998.1 - 1.9e-19 69.8 0.0 6.6e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EPE35998.1 - 3.4e-19 69.2 10.5 3.4e-19 69.2 10.5 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component UQ_con PF00179.26 EPE36000.1 - 1.1e-51 174.1 0.0 1.8e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Acyl-CoA_dh_N PF02771.16 EPE36000.1 - 1.1e-24 87.3 0.2 9.4e-24 84.3 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EPE36000.1 - 1.3e-20 74.1 0.0 2.2e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EPE36000.1 - 1.2e-14 54.3 0.0 2.3e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EPE36000.1 - 0.00096 19.4 0.1 0.0036 17.6 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Prok-E2_B PF14461.6 EPE36000.1 - 0.049 13.3 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B XPG_I PF00867.18 EPE36001.1 - 3e-30 104.4 1.7 5.2e-30 103.7 0.0 2.1 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EPE36001.1 - 8.6e-15 55.1 1.6 1.3e-14 54.5 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EPE36001.1 - 3.3e-05 24.4 0.3 0.00022 21.8 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.11 EPE36001.1 - 0.035 13.7 3.1 0.063 12.8 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Monellin PF09200.10 EPE36001.1 - 0.035 14.0 0.5 0.099 12.5 0.1 2.0 2 0 0 2 2 2 0 Monellin Fe_dep_repr_C PF02742.15 EPE36001.1 - 0.063 13.4 0.0 14 5.9 0.0 2.9 3 0 0 3 3 3 0 Iron dependent repressor, metal binding and dimerisation domain HHH_5 PF14520.6 EPE36001.1 - 0.073 13.7 0.0 0.2 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain RCC1 PF00415.18 EPE36002.1 - 9.2e-30 103.0 5.2 2e-06 28.3 0.0 7.5 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EPE36002.1 - 3.4e-14 52.2 22.0 4.9e-09 35.7 0.0 6.9 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat DUF1459 PF07312.11 EPE36002.1 - 0.46 10.7 1.6 1.1 9.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) Sec34 PF04136.15 EPE36003.1 - 1.1e-48 164.9 1.4 2.2e-48 163.9 0.3 2.2 3 0 0 3 3 3 1 Sec34-like family SKA2 PF16740.5 EPE36003.1 - 0.012 15.4 1.1 0.022 14.5 0.1 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF5089 PF17002.5 EPE36003.1 - 0.62 9.9 3.2 4.3 7.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5089) Abhydrolase_6 PF12697.7 EPE36004.1 - 9.2e-10 39.5 0.0 1.3e-09 39.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE36004.1 - 7.6e-06 25.4 0.0 1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE36004.1 - 0.0016 18.2 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3391 PF11871.8 EPE36005.1 - 0.17 12.4 0.1 0.33 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Bromodomain PF00439.25 EPE36006.1 - 5.3e-37 125.8 10.9 8.7e-18 64.2 0.3 3.2 2 1 1 3 3 3 2 Bromodomain BAH PF01426.18 EPE36006.1 - 9.2e-18 64.3 0.7 2.4e-17 62.9 0.7 1.8 1 0 0 1 1 1 1 BAH domain OTU PF02338.19 EPE36007.1 - 1e-06 29.2 0.0 2.2e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 OTU-like cysteine protease PB1 PF00564.24 EPE36007.1 - 0.14 12.1 0.0 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 PB1 domain Glyco_hydro_17 PF00332.18 EPE36008.1 - 9.4e-11 41.9 0.8 2e-09 37.5 0.4 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Ribosomal_S26e PF01283.19 EPE36009.1 - 4.9e-49 165.3 4.5 8.2e-49 164.5 4.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 EPE36009.1 - 0.081 12.9 0.5 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 EPE36009.1 - 0.17 11.7 0.6 0.28 11.0 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) ubiquitin PF00240.23 EPE36010.1 - 1.5e-32 111.1 0.3 2.6e-32 110.4 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 EPE36010.1 - 1.2e-26 92.6 2.2 1.2e-26 92.6 2.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EPE36010.1 - 2e-14 53.1 0.3 3.7e-14 52.3 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EPE36010.1 - 0.00011 22.6 0.2 0.0005 20.5 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EPE36010.1 - 0.00083 19.4 0.4 0.0018 18.4 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EPE36010.1 - 0.0072 16.6 0.6 0.014 15.7 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EPE36010.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain IBR PF01485.21 EPE36010.1 - 0.024 14.8 0.2 0.042 14.1 0.2 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF2407 PF10302.9 EPE36010.1 - 0.045 14.3 0.4 0.063 13.9 0.4 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DnaJ PF00226.31 EPE36012.1 - 8.3e-08 32.2 0.1 3.2e-07 30.4 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain Glyco_hydro_18 PF00704.28 EPE36013.1 - 1e-87 294.8 3.5 1.2e-87 294.6 3.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ELYS PF13934.6 EPE36014.1 - 1.3e-62 211.7 0.1 1.8e-62 211.2 0.1 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.19 EPE36015.1 - 8.8e-78 260.7 0.0 5.7e-77 258.1 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EPE36015.1 - 5.5e-24 84.7 0.0 2.2e-23 82.8 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EPE36015.1 - 8.5e-12 45.5 2.4 5.8e-05 23.0 0.1 3.5 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Filament PF00038.21 EPE36015.1 - 0.00048 19.8 40.9 0.00048 19.8 40.9 4.4 2 2 1 3 3 3 1 Intermediate filament protein AAA_29 PF13555.6 EPE36015.1 - 0.0006 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.6 EPE36015.1 - 0.00068 19.0 11.2 0.00068 19.0 11.2 7.6 2 2 3 7 7 7 4 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.19 EPE36015.1 - 0.001 17.0 50.4 0.001 17.0 50.4 3.9 2 2 2 4 4 4 1 Myosin tail Tektin PF03148.14 EPE36015.1 - 0.0013 17.6 12.2 0.0013 17.6 12.2 6.0 2 2 1 4 4 4 1 Tektin family FlaC_arch PF05377.11 EPE36015.1 - 0.0072 16.7 2.6 0.0072 16.7 2.6 9.0 10 2 1 11 11 11 1 Flagella accessory protein C (FlaC) ABC_tran PF00005.27 EPE36015.1 - 2.1 8.9 0.0 2.1 8.9 0.0 6.1 3 2 0 3 3 3 0 ABC transporter SKG6 PF08693.10 EPE36016.1 - 1.1e-07 31.1 0.0 2.5e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Amnionless PF14828.6 EPE36016.1 - 0.00069 18.6 0.1 0.00085 18.3 0.1 1.1 1 0 0 1 1 1 1 Amnionless Rab5ip PF07019.12 EPE36016.1 - 0.036 14.6 0.1 0.072 13.7 0.1 1.5 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) Linker_histone PF00538.19 EPE36019.1 - 8.3e-28 96.6 0.4 1.7e-27 95.6 0.4 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family Ribosomal_L27e PF01777.18 EPE36020.1 - 3e-36 123.7 2.7 4.7e-36 123.0 2.7 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EPE36020.1 - 0.013 15.5 1.2 0.027 14.4 0.5 2.0 2 0 0 2 2 2 0 KOW motif TPT PF03151.16 EPE36021.1 - 1.1e-26 93.9 21.2 1.5e-26 93.5 21.2 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EPE36021.1 - 0.00036 20.7 36.2 0.0021 18.2 14.2 2.7 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 EPE36021.1 - 0.0024 17.2 23.5 0.0033 16.7 23.5 1.2 1 0 0 1 1 1 1 UAA transporter family UBA_2 PF08587.11 EPE36022.1 - 0.0067 16.5 10.9 4.6 7.4 0.0 8.3 10 1 0 10 10 10 1 Ubiquitin associated domain (UBA) DUF4208 PF13907.6 EPE36022.1 - 0.26 11.8 6.7 4.7 7.7 0.1 5.8 5 1 1 6 6 6 0 Domain of unknown function (DUF4208) Tup_N PF08581.10 EPE36022.1 - 0.31 11.4 25.4 0.76 10.1 0.2 8.0 5 1 1 6 6 6 0 Tup N-terminal PHP_C PF13263.6 EPE36022.1 - 0.7 9.7 4.7 1.9e+02 1.9 0.0 6.1 6 0 0 6 6 6 0 PHP-associated CEP63 PF17045.5 EPE36022.1 - 0.86 9.4 33.2 2.2 8.1 0.5 6.2 4 3 1 6 6 6 0 Centrosomal protein of 63 kDa Caskin1-CID PF16600.5 EPE36022.1 - 1.2 9.8 4.4 5.6 7.6 4.4 2.2 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain DivIC PF04977.15 EPE36022.1 - 2.8 7.8 11.1 0.58 10.0 2.7 4.4 3 0 0 3 3 3 0 Septum formation initiator HeLo PF14479.6 EPE36022.1 - 4.5 7.1 18.8 0.7 9.7 0.1 5.3 5 0 0 5 5 5 0 Prion-inhibition and propagation IGR PF09597.10 EPE36023.1 - 8.8e-26 89.8 1.3 1e-25 89.6 0.3 1.7 2 0 0 2 2 2 1 IGR protein motif CCDC85 PF10226.9 EPE36025.1 - 0.0057 16.4 0.5 0.016 14.9 0.5 1.7 1 0 0 1 1 1 1 CCDC85 family UPF0242 PF06785.11 EPE36025.1 - 3.5 7.7 7.9 0.7 10.0 0.7 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LSM PF01423.22 EPE36026.1 - 1.2e-21 76.2 0.5 1.4e-21 76.0 0.5 1.1 1 0 0 1 1 1 1 LSM domain Rhodanese PF00581.20 EPE36027.1 - 2.1e-07 31.4 0.0 3.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Cytochrome_CBB3 PF13442.6 EPE36027.1 - 0.079 13.3 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Methyltransf_31 PF13847.6 EPE36029.1 - 1.8e-18 66.8 0.0 2.8e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE36029.1 - 2e-16 60.5 0.0 3.4e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE36029.1 - 1.3e-13 51.4 0.0 2.3e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE36029.1 - 7.7e-11 42.6 0.0 1.2e-10 42.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE36029.1 - 2.8e-08 33.8 0.0 3.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPE36029.1 - 2.2e-07 30.6 0.0 3.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EPE36029.1 - 1.1e-06 28.2 0.1 2.1e-06 27.2 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EPE36029.1 - 1.1e-06 28.6 0.0 1.6e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EPE36029.1 - 5.2e-06 26.1 0.0 8.2e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EPE36029.1 - 6.1e-06 26.3 0.0 8.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EPE36029.1 - 1.5e-05 24.5 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.18 EPE36029.1 - 3.9e-05 23.4 0.0 0.0011 18.6 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 GCD14 PF08704.10 EPE36029.1 - 0.0037 17.0 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_15 PF09445.10 EPE36029.1 - 0.034 13.7 0.5 0.3 10.6 0.1 2.0 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 EPE36029.1 - 0.05 13.5 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 EPE36029.1 - 0.092 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Met_10 PF02475.16 EPE36029.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltr_RsmB-F PF01189.17 EPE36029.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F MetW PF07021.12 EPE36029.1 - 0.16 11.6 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Amidase PF01425.21 EPE36030.1 - 2.9e-94 316.6 0.0 3.9e-94 316.1 0.0 1.2 1 0 0 1 1 1 1 Amidase Lactamase_B PF00753.27 EPE36031.1 - 2.7e-05 24.2 0.0 5.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Zn_clus PF00172.18 EPE36032.1 - 3.3e-07 30.3 8.4 6.5e-07 29.4 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE36032.1 - 0.0034 16.4 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1590 PF07629.11 EPE36032.1 - 0.35 10.7 3.2 2.5 8.0 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) FeS_assembly_P PF01883.19 EPE36033.1 - 9.5e-08 32.1 0.1 6.7e-07 29.4 0.1 2.3 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein GTP_EFTU PF00009.27 EPE36034.1 - 7.4e-49 165.9 0.0 1.1e-48 165.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EPE36034.1 - 6.8e-37 126.8 8.4 1.3e-36 125.9 8.4 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EPE36034.1 - 2.4e-21 75.8 0.0 7.3e-21 74.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EPE36034.1 - 3e-18 65.6 0.0 9.9e-18 64.0 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EPE36034.1 - 2.4e-09 37.4 0.0 5.8e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EPE36034.1 - 5.5e-07 29.6 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EPE36034.1 - 2e-05 24.7 0.2 3.6e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EPE36034.1 - 0.15 11.4 0.2 1.8 8.0 0.2 2.2 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Thiolase_N PF00108.23 EPE36035.1 - 3.6e-94 314.9 0.4 3.6e-94 314.9 0.4 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EPE36035.1 - 2.5e-45 153.1 1.0 2.5e-45 153.1 1.0 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EPE36035.1 - 3.8e-05 23.4 0.3 3.8e-05 23.4 0.3 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EPE36035.1 - 0.017 15.0 1.6 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GNAT_acetyltr_2 PF13718.6 EPE36036.1 - 1.6e-98 328.7 0.0 3.5e-98 327.6 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EPE36036.1 - 2.4e-89 299.1 0.0 5.9e-89 297.8 0.0 1.7 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EPE36036.1 - 1.9e-64 216.8 0.1 6.7e-64 215.0 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EPE36036.1 - 1.5e-34 117.8 0.0 3.9e-34 116.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 EPE36036.1 - 0.00011 22.0 0.1 0.033 13.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EPE36036.1 - 0.0016 18.7 0.0 0.044 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain GHMP_kinases_N PF00288.26 EPE36036.1 - 0.12 12.6 0.2 0.33 11.2 0.2 1.7 1 0 0 1 1 1 0 GHMP kinases N terminal domain Amidoligase_2 PF12224.8 EPE36037.1 - 3.4e-20 72.8 0.1 1.8e-19 70.4 0.1 2.1 1 1 0 1 1 1 1 Putative amidoligase enzyme HATPase_c PF02518.26 EPE36038.1 - 4.8e-30 104.3 0.2 1.4e-29 102.9 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPE36038.1 - 9.9e-22 77.2 0.1 2.5e-21 75.9 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPE36038.1 - 1.8e-20 72.7 0.1 4.9e-20 71.3 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EPE36038.1 - 1.4e-15 57.4 0.7 4.7e-15 55.7 0.7 2.0 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EPE36038.1 - 5.1e-10 39.5 0.0 0.0011 19.2 0.0 4.4 4 0 0 4 4 4 2 PAS domain PAS_4 PF08448.10 EPE36038.1 - 3.8e-08 33.6 0.3 9.2e-06 25.9 0.0 3.7 4 0 0 4 4 4 1 PAS fold PAS PF00989.25 EPE36038.1 - 9.7e-05 22.3 0.0 0.25 11.4 0.0 4.3 4 0 0 4 4 4 1 PAS fold PAS_8 PF13188.7 EPE36038.1 - 0.00038 20.4 0.0 0.042 13.9 0.0 3.2 3 0 0 3 3 3 1 PAS domain HATPase_c_3 PF13589.6 EPE36038.1 - 0.016 15.0 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MLTR_LBD PF17765.1 EPE36038.1 - 0.096 12.8 0.2 1 9.5 0.0 2.4 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain LNS2 PF08235.13 EPE36039.1 - 1.4e-91 306.0 0.0 1.9e-91 305.5 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EPE36039.1 - 1e-42 144.2 0.0 2e-42 143.3 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 EPE36039.1 - 0.12 11.9 0.2 0.6 9.6 0.0 2.1 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) WRNPLPNID PF15017.6 EPE36039.1 - 7.5 7.5 18.7 2.4e+02 2.7 19.0 3.4 2 1 0 2 2 2 0 Putative WW-binding domain and destruction box SNARE_assoc PF09335.11 EPE36040.1 - 4.2e-15 56.3 3.9 4.2e-15 56.3 3.9 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein ATG16 PF08614.11 EPE36041.1 - 0.5 10.6 3.9 0.13 12.5 0.6 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) F-box-like PF12937.7 EPE36042.1 - 0.031 14.2 0.1 0.067 13.1 0.1 1.6 1 0 0 1 1 1 0 F-box-like zf-RING_UBOX PF13445.6 EPE36043.1 - 1e-07 31.8 4.5 1e-07 31.8 4.5 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EPE36043.1 - 2.5e-06 27.7 9.8 4.7e-06 26.8 9.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EPE36043.1 - 2.6e-06 27.2 7.4 4.5e-06 26.4 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE36043.1 - 2.7e-06 27.1 11.0 5e-06 26.3 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE36043.1 - 1.5e-05 24.9 8.9 2.6e-05 24.1 8.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EPE36043.1 - 2.9e-05 23.8 10.3 6.4e-05 22.7 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE36043.1 - 0.015 15.2 11.7 0.15 11.9 11.5 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EPE36043.1 - 0.057 13.5 3.3 0.11 12.5 3.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EPE36043.1 - 0.063 13.4 10.9 0.15 12.2 10.5 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EPE36043.1 - 0.081 12.7 6.3 0.28 11.0 6.4 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.12 EPE36043.1 - 0.11 12.6 3.9 0.21 11.6 3.9 1.5 1 0 0 1 1 1 0 zinc-ribbons zinc_ribbon_9 PF14369.6 EPE36043.1 - 0.11 12.8 5.9 0.27 11.5 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon Cys_rich_KTR PF14205.6 EPE36043.1 - 7.1 6.5 6.3 28 4.6 1.8 2.6 1 1 1 2 2 2 0 Cysteine-rich KTR HTH_23 PF13384.6 EPE36044.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Homeodomain-like domain Tox-REase-7 PF15649.6 EPE36044.1 - 0.088 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 7 Tox-SHH PF15652.6 EPE36044.1 - 0.11 13.5 0.0 0.13 13.2 0.0 1.3 1 0 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature PAXX PF15384.6 EPE36045.1 - 0.13 11.9 0.0 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Ctr PF04145.15 EPE36046.1 - 5.5e-13 49.8 0.3 6.6e-13 49.5 0.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Abhydrolase_6 PF12697.7 EPE36047.1 - 1.3e-19 71.7 0.1 1.5e-19 71.5 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE36047.1 - 0.0015 17.8 0.0 0.13 11.6 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE36047.1 - 0.016 14.8 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 EPE36048.1 - 7.6e-07 28.3 0.1 9.2e-07 28.0 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE36048.1 - 0.00073 19.6 9.4 0.00073 19.6 9.4 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flu_NS2 PF00601.19 EPE36048.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Influenza non-structural protein (NS2) Peptidase_S9 PF00326.21 EPE36049.1 - 4.9e-54 183.0 0.0 9.5e-54 182.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 EPE36049.1 - 4.5e-05 23.3 0.1 0.015 15.3 0.1 3.7 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 EPE36049.1 - 0.012 15.3 1.2 0.05 13.2 0.5 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Pkinase PF00069.25 EPE36050.1 - 4.8e-36 124.5 0.0 4.2e-20 72.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE36050.1 - 2.2e-14 53.4 0.0 1.5e-13 50.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPE36050.1 - 0.00053 20.0 0.1 0.0011 18.9 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family VitD-bind_III PF09164.10 EPE36051.1 - 0.17 11.9 0.4 0.17 11.9 0.4 2.1 2 0 0 2 2 2 0 Vitamin D binding protein, domain III FapA PF03961.13 EPE36051.1 - 5 5.6 8.4 4.5 5.8 6.9 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A OmpH PF03938.14 EPE36051.1 - 7.2 6.9 13.8 16 5.8 13.8 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DEAD PF00270.29 EPE36052.1 - 3.5e-46 157.2 1.0 5.6e-46 156.5 1.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE36052.1 - 2.3e-31 108.4 0.1 1.7e-30 105.6 0.0 2.4 2 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE36052.1 - 1.5e-06 28.3 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EPE36052.1 - 0.00044 20.0 0.1 0.00079 19.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPE36052.1 - 0.0037 17.6 0.6 0.025 14.9 0.4 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPE36052.1 - 0.0086 16.4 0.3 0.03 14.6 0.3 2.0 1 1 0 1 1 1 1 AAA domain IL17R_D_N PF16742.5 EPE36052.1 - 0.011 15.8 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D CMS1 PF14617.6 EPE36052.1 - 0.017 14.5 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 EPE36052.1 - 0.11 12.4 0.1 0.6 10.1 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Cupin_8 PF13621.6 EPE36053.1 - 1.7e-15 57.5 0.1 1.5e-13 51.0 0.1 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EPE36053.1 - 1.5e-09 38.3 0.1 1.6e-08 34.9 0.1 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 EPE36053.1 - 0.00045 20.1 0.1 0.0011 18.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE36053.1 - 0.0016 18.3 0.0 0.0042 16.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain NuA4 PF09340.10 EPE36054.1 - 6.6e-22 77.2 0.2 1.2e-21 76.4 0.0 1.5 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 PWI PF01480.17 EPE36055.1 - 6.3e-32 109.7 0.4 1e-31 109.0 0.4 1.4 1 0 0 1 1 1 1 PWI domain FAA_hydrolase PF01557.18 EPE36058.1 - 4.7e-51 173.5 0.0 5.6e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.12 EPE36059.1 - 9.7e-61 203.8 0.0 1.1e-60 203.6 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EPE36059.1 - 4e-05 23.3 0.0 6.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain DZR PF12773.7 EPE36059.1 - 0.0018 18.3 2.5 0.0033 17.4 2.5 1.4 1 0 0 1 1 1 1 Double zinc ribbon AraC_binding PF02311.19 EPE36059.1 - 0.0039 17.1 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain TF_Zn_Ribbon PF08271.12 EPE36059.1 - 0.0081 15.7 0.5 0.65 9.6 0.0 2.6 2 0 0 2 2 2 1 TFIIB zinc-binding Cupin_1 PF00190.22 EPE36059.1 - 0.014 15.0 0.1 0.02 14.5 0.1 1.2 1 0 0 1 1 1 0 Cupin Nudix_N_2 PF14803.6 EPE36059.1 - 0.015 15.2 1.0 6.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Nudix N-terminal Cupin_4 PF08007.12 EPE36059.1 - 0.046 13.2 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein FYVE PF01363.21 EPE36059.1 - 0.057 13.6 1.4 0.1 12.7 1.4 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-ribbon_3 PF13248.6 EPE36059.1 - 0.06 12.8 2.6 6.6 6.3 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain ARD PF03079.14 EPE36059.1 - 0.092 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 ARD/ARD' family HalOD2 PF18547.1 EPE36059.1 - 0.17 11.8 1.4 5.9 6.9 0.1 2.4 2 0 0 2 2 2 0 Halobacterial output domain 2 zf-ACC PF17848.1 EPE36059.1 - 0.37 10.9 3.9 13 6.0 0.1 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain RecR PF02132.15 EPE36059.1 - 0.83 9.3 3.2 2.3 7.8 0.4 2.4 1 1 1 2 2 2 0 RecR protein ADK_lid PF05191.14 EPE36059.1 - 1 9.4 5.9 37 4.4 6.2 2.5 1 1 0 1 1 1 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.10 EPE36059.1 - 1.3 9.2 5.4 46 4.2 5.4 2.2 1 1 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 EPE36059.1 - 1.3 8.8 7.8 7.4 6.4 0.6 2.7 3 0 0 3 3 2 0 zinc-ribbon domain YhfH PF14149.6 EPE36059.1 - 4.1 7.5 7.6 7.8 6.6 0.0 3.2 3 1 1 4 4 3 0 YhfH-like protein U1snRNP70_N PF12220.8 EPE36060.1 - 0.33 11.6 7.2 13 6.5 0.3 3.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Glyco_hydro_71 PF03659.14 EPE36061.1 - 8.8e-127 423.0 0.6 1e-126 422.7 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Gag_p10 PF02337.17 EPE36061.1 - 0.52 10.3 3.4 2.4 8.2 1.1 2.6 3 0 0 3 3 3 0 Retroviral GAG p10 protein Glyco_hydro_38N PF01074.22 EPE36062.1 - 1.9e-87 293.3 1.1 1.9e-87 293.3 1.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EPE36062.1 - 3.6e-56 190.6 0.3 2.4e-55 187.9 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EPE36062.1 - 1.3e-28 99.0 0.0 2.9e-28 97.8 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EPE36062.1 - 6.4e-12 45.4 0.1 2.4e-11 43.6 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Pro_CA PF00484.19 EPE36063.1 - 1.3e-14 54.7 0.2 2.8e-14 53.7 0.2 1.5 1 1 0 1 1 1 1 Carbonic anhydrase NUDIX PF00293.28 EPE36064.1 - 1.8e-10 41.0 0.0 4.5e-10 39.7 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain CMD PF02627.20 EPE36065.1 - 6.9e-19 67.7 0.2 1.4e-18 66.7 0.2 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family peroxidase PF00141.23 EPE36066.1 - 1.2e-46 159.2 0.0 1.9e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Nop14 PF04147.12 EPE36068.1 - 2.3e-292 972.5 28.2 2.7e-292 972.2 28.2 1.0 1 0 0 1 1 1 1 Nop14-like family Ribosomal_L36e PF01158.18 EPE36069.1 - 2.3e-40 136.7 7.1 2.6e-40 136.5 7.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.9 EPE36069.1 - 0.012 15.7 1.8 0.014 15.5 1.8 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 PBS_linker_poly PF00427.21 EPE36069.1 - 0.1 12.7 0.3 0.12 12.5 0.3 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide TUG-UBL1 PF11470.8 EPE36070.1 - 1.1e-24 86.5 0.0 3.7e-24 84.7 0.0 1.9 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 EPE36070.1 - 1.4e-06 28.4 0.0 6.2e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 UBX domain TRAPP PF04051.16 EPE36070.1 - 0.037 13.8 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component DUF3811 PF11656.8 EPE36070.1 - 4 7.9 7.7 0.71 10.3 0.4 2.4 2 0 0 2 2 2 0 YjbD family (DUF3811) Proteasome PF00227.26 EPE36071.1 - 2.3e-40 138.1 0.0 2.8e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit E1-E2_ATPase PF00122.20 EPE36072.1 - 2.8e-49 167.1 6.6 7e-49 165.8 2.4 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EPE36072.1 - 1.5e-45 155.2 5.8 2.9e-45 154.2 5.8 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EPE36072.1 - 1.3e-24 87.6 2.0 9.7e-24 84.8 2.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPE36072.1 - 7.2e-20 70.9 0.0 1.4e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EPE36072.1 - 1.2e-18 66.5 0.2 3.2e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EPE36072.1 - 2.3e-08 34.1 2.2 2.6e-06 27.3 1.3 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EPE36072.1 - 6.5e-06 26.7 0.0 2e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase baeRF_family2 PF18844.1 EPE36072.1 - 0.038 14.1 0.1 20 5.2 0.0 3.3 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 2 DUF3431 PF11913.8 EPE36073.1 - 7.3e-87 290.7 0.9 9.2e-87 290.3 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) PAS_9 PF13426.7 EPE36074.1 - 3.1e-15 56.3 0.0 2.3e-12 47.1 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 EPE36074.1 - 0.0011 19.0 0.0 0.029 14.4 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EPE36074.1 - 0.017 15.4 0.0 0.41 10.9 0.0 2.5 2 0 0 2 2 2 0 PAS fold BAR PF03114.18 EPE36075.1 - 8.2e-53 179.5 7.1 1.1e-52 179.1 7.1 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 EPE36075.1 - 4.6e-06 26.0 4.1 8.6e-06 25.1 4.1 1.4 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF3086 PF11285.8 EPE36075.1 - 0.018 14.1 0.5 0.028 13.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) HAUS6_N PF14661.6 EPE36075.1 - 0.1 12.1 4.2 0.047 13.3 1.6 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus OmpH PF03938.14 EPE36075.1 - 0.32 11.3 9.5 0.35 11.2 7.4 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PMEI PF04043.15 EPE36075.1 - 0.36 11.1 3.1 1.7 9.0 3.1 2.0 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Arfaptin PF06456.13 EPE36075.1 - 0.79 9.3 8.1 1.8 8.1 8.1 1.7 1 1 0 1 1 1 0 Arfaptin-like domain Uds1 PF15456.6 EPE36075.1 - 1.3 9.2 11.9 1.8 8.8 7.3 2.4 2 0 0 2 2 2 0 Up-regulated During Septation APG6_N PF17675.1 EPE36075.1 - 6.4 7.3 12.4 18 5.8 12.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region zf-C3HC4_2 PF13923.6 EPE36076.1 - 3.4e-10 39.6 8.7 8.5e-10 38.3 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE36076.1 - 3.5e-10 40.1 9.3 7.8e-10 38.9 9.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EPE36076.1 - 2.3e-09 37.0 6.7 3.9e-09 36.2 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE36076.1 - 1.1e-08 34.9 7.4 8.2e-08 32.2 3.4 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EPE36076.1 - 1.5e-08 34.4 9.4 3.7e-08 33.1 9.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPE36076.1 - 9.9e-07 29.0 5.1 2.4e-06 27.7 5.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EPE36076.1 - 1.9e-06 27.7 7.4 3.6e-06 26.8 7.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EPE36076.1 - 2.3e-06 27.6 10.7 4.8e-06 26.6 10.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EPE36076.1 - 6.2e-06 26.0 10.9 7.8e-05 22.5 11.2 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EPE36076.1 - 4.2e-05 23.5 2.3 8.5e-05 22.5 2.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 EPE36076.1 - 0.016 15.1 4.4 0.041 13.8 2.5 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Siva PF05458.12 EPE36076.1 - 0.022 14.5 0.7 0.042 13.5 0.7 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) zf-RING_11 PF17123.5 EPE36076.1 - 0.034 13.9 10.7 0.28 10.9 6.8 2.6 2 0 0 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EPE36076.1 - 0.062 12.9 6.0 0.16 11.6 6.0 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EPE36076.1 - 0.091 12.6 7.1 0.19 11.6 7.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.20 EPE36076.1 - 0.2 11.4 7.1 0.48 10.2 7.1 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zinc-ribbons_6 PF07191.12 EPE36076.1 - 0.23 11.5 4.7 0.53 10.3 4.7 1.6 1 0 0 1 1 1 0 zinc-ribbons zf-Nse PF11789.8 EPE36076.1 - 1.4 8.8 7.5 2.1 8.2 6.2 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 EPE36076.1 - 2.6 7.8 11.6 0.27 10.9 6.6 2.0 2 1 0 2 2 1 0 P-11 zinc finger IBR PF01485.21 EPE36076.1 - 3.6 7.9 7.9 7.7 6.8 6.1 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Git3 PF11710.8 EPE36077.1 - 1.6e-21 77.0 12.5 2.8e-21 76.2 12.5 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EPE36077.1 - 0.078 13.1 0.1 0.078 13.1 0.1 2.4 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Presenilin PF01080.17 EPE36077.1 - 9.7 4.8 8.3 5 5.8 4.7 2.2 2 0 0 2 2 2 0 Presenilin ABC_tran PF00005.27 EPE36078.1 - 7.4e-48 162.5 0.0 6.5e-23 81.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EPE36078.1 - 1e-20 73.5 5.5 1e-20 73.5 5.5 2.2 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 EPE36078.1 - 4e-19 69.5 0.4 0.00033 20.6 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPE36078.1 - 2.1e-10 40.4 0.1 0.0019 17.7 0.1 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EPE36078.1 - 1.2e-08 35.7 1.7 0.032 14.7 0.1 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EPE36078.1 - 3.1e-08 33.2 0.1 0.0032 17.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EPE36078.1 - 3.2e-07 30.4 0.0 0.026 14.2 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EPE36078.1 - 1.4e-06 28.3 1.3 0.0027 17.6 0.1 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 EPE36078.1 - 2.5e-06 28.0 0.0 0.011 16.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EPE36078.1 - 6.2e-06 26.8 0.1 0.089 13.3 0.0 3.1 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 EPE36078.1 - 1e-05 25.5 0.0 0.015 15.4 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EPE36078.1 - 1.1e-05 25.7 0.0 0.038 14.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EPE36078.1 - 0.00015 22.1 1.2 1.4 9.4 0.0 3.4 3 0 0 3 3 3 1 RNA helicase AAA_28 PF13521.6 EPE36078.1 - 0.0003 21.1 0.0 0.13 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EPE36078.1 - 0.00048 20.1 0.3 0.73 9.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain NB-ARC PF00931.22 EPE36078.1 - 0.00051 19.3 0.1 2 7.5 0.0 3.1 2 1 0 2 2 2 2 NB-ARC domain AAA PF00004.29 EPE36078.1 - 0.00055 20.4 0.0 0.91 10.0 0.0 3.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EPE36078.1 - 0.00079 19.4 0.1 1.3 9.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_27 PF13514.6 EPE36078.1 - 0.0018 17.9 0.0 0.63 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EPE36078.1 - 0.0025 18.0 0.0 0.22 11.7 0.1 2.9 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EPE36078.1 - 0.0042 17.3 0.1 2.8 8.2 0.0 3.1 2 1 1 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EPE36078.1 - 0.0045 17.0 0.0 3 7.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EPE36078.1 - 0.011 15.5 3.6 2 8.1 0.1 3.5 4 0 0 4 4 3 0 AAA domain DUF2813 PF11398.8 EPE36078.1 - 0.012 14.9 0.0 4.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) ABC_ATPase PF09818.9 EPE36078.1 - 0.018 13.9 0.1 15 4.2 0.0 3.4 3 1 0 3 3 3 0 Predicted ATPase of the ABC class AAA_17 PF13207.6 EPE36078.1 - 0.018 15.5 0.0 8 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EPE36078.1 - 0.021 14.4 0.1 0.92 9.0 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 EPE36078.1 - 0.027 14.0 0.2 0.78 9.3 0.0 3.0 4 0 0 4 4 3 0 AAA domain MCM PF00493.23 EPE36078.1 - 0.042 12.9 0.1 4.2 6.4 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain DUF815 PF05673.13 EPE36078.1 - 0.066 12.4 0.1 3.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 EPE36078.1 - 0.067 12.9 1.1 4.1 7.1 0.1 3.1 3 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EPE36078.1 - 0.069 13.1 0.0 3.1 7.7 0.0 2.7 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 EPE36078.1 - 0.09 12.5 0.4 7.3 6.3 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EPE36078.1 - 0.1 12.1 0.0 11 5.5 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B Rad17 PF03215.15 EPE36078.1 - 0.11 12.5 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain TsaE PF02367.17 EPE36078.1 - 0.14 12.2 0.7 7.7 6.5 0.0 3.0 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3584 PF12128.8 EPE36078.1 - 0.18 9.3 1.1 0.24 8.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DAP3 PF10236.9 EPE36078.1 - 0.18 10.9 1.1 10 5.2 0.1 2.8 2 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 SNF2_N PF00176.23 EPE36079.1 - 3.2e-63 213.6 0.6 5.8e-63 212.7 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 EPE36079.1 - 6.5e-48 162.5 18.2 6.5e-48 162.5 18.2 4.7 5 1 1 6 6 6 1 DNA-binding domain Helicase_C PF00271.31 EPE36079.1 - 1.4e-19 70.5 0.0 3.6e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE36079.1 - 1.2e-06 28.6 0.0 1.2e-06 28.6 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EPE36079.1 - 0.002 17.9 0.0 0.0056 16.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EPE36079.1 - 0.2 10.8 0.0 0.2 10.8 0.0 2.4 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 Exo_endo_phos PF03372.23 EPE36080.1 - 2.3e-08 33.8 0.0 4.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4660 PF15559.6 EPE36080.1 - 0.67 10.3 5.5 0.17 12.2 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) Biotin_lipoyl PF00364.22 EPE36081.1 - 1.5e-20 72.7 0.7 4.1e-20 71.4 0.7 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EPE36081.1 - 2.5e-07 30.9 0.0 8e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EPE36081.1 - 6.3e-05 22.7 0.0 0.00062 19.5 0.0 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like DUF1631 PF07793.11 EPE36081.1 - 0.041 12.3 2.5 0.056 11.9 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF4518 PF15008.6 EPE36082.1 - 0.25 10.5 0.6 0.37 9.9 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) LRR_4 PF12799.7 EPE36083.1 - 1.1e-13 51.1 3.3 0.0022 18.4 0.5 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EPE36083.1 - 2e-11 43.5 7.2 3.3e-07 30.0 3.3 3.5 1 1 3 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 EPE36083.1 - 8.8e-05 22.1 0.4 0.00043 19.8 0.3 1.9 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 EPE36083.1 - 0.00017 21.4 8.1 5.3 7.4 0.1 5.4 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 EPE36083.1 - 0.0012 19.1 9.5 44 5.2 0.3 6.1 5 1 0 5 5 5 0 Leucine Rich Repeat Metallophos PF00149.28 EPE36084.1 - 4e-40 138.5 0.1 5.2e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EPE36084.1 - 3.2e-23 81.9 1.8 4.7e-23 81.4 1.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Rdx PF10262.9 EPE36085.1 - 3.3e-20 72.0 0.0 6.1e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.22 EPE36086.1 - 5.6e-24 83.9 0.0 7e-24 83.6 0.0 1.1 1 0 0 1 1 1 1 GGL domain DUF3591 PF12157.8 EPE36087.1 - 7.1e-174 578.6 0.4 9.8e-174 578.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 EPE36087.1 - 0.0093 16.0 0.9 0.021 14.9 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle PCI PF01399.27 EPE36088.1 - 3e-08 34.1 0.8 1e-07 32.4 0.1 2.3 2 0 0 2 2 2 1 PCI domain WSC PF01822.19 EPE36089.1 - 1.3e-27 95.8 26.3 2.5e-17 62.8 6.3 7.3 6 1 0 7 7 7 2 WSC domain Dioxygenase_C PF00775.21 EPE36090.1 - 5.5e-10 39.0 0.2 1.3e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 Dioxygenase Forkhead PF00250.18 EPE36091.1 - 8.4e-34 115.7 0.3 1.5e-33 114.9 0.3 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EPE36091.1 - 2.9e-09 37.1 0.1 8.8e-09 35.6 0.0 1.9 2 1 0 2 2 2 1 FHA domain Aminotran_3 PF00202.21 EPE36092.1 - 9.2e-82 274.9 0.0 1.2e-81 274.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EPE36092.1 - 0.0084 15.3 0.0 0.2 10.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II CLU PF13236.6 EPE36093.1 - 9.8e-75 251.2 0.0 1.8e-74 250.3 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EPE36093.1 - 4.4e-51 173.4 0.1 1.2e-50 172.0 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EPE36093.1 - 5.7e-25 87.4 4.2 6e-09 36.1 0.1 3.9 2 1 1 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 EPE36093.1 - 9.8e-24 83.5 0.1 3.9e-23 81.6 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 EPE36093.1 - 1.7e-23 81.8 1.5 2.2e-07 30.5 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EPE36093.1 - 4e-06 26.6 4.7 0.05 13.8 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPE36093.1 - 0.00022 21.1 2.9 0.23 11.7 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EPE36093.1 - 0.0024 17.7 0.2 2.5 8.4 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF727 PF05303.12 EPE36093.1 - 0.027 14.5 0.0 0.076 13.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF727) TPR_1 PF00515.28 EPE36093.1 - 0.069 13.0 1.3 23 5.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ferric_reduct PF01794.19 EPE36095.1 - 3.7e-22 78.8 11.0 9.2e-22 77.5 11.0 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EPE36095.1 - 9.8e-20 71.3 0.0 2e-11 44.2 0.0 2.6 2 1 1 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EPE36095.1 - 2.3e-12 47.0 0.0 2.1e-08 34.2 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain Peptidase_A4 PF01828.17 EPE36096.1 - 2e-46 158.1 0.2 2.5e-46 157.8 0.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family Yippee-Mis18 PF03226.14 EPE36097.1 - 7.1e-17 61.5 0.7 7.9e-17 61.4 0.7 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EPE36097.1 - 0.0025 18.0 1.2 0.0036 17.5 1.2 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I HNH_5 PF14279.6 EPE36097.1 - 0.0057 16.5 1.2 0.028 14.3 0.0 2.1 2 0 0 2 2 2 1 HNH endonuclease Endonuclease_7 PF02945.15 EPE36097.1 - 0.016 15.2 2.6 0.037 14.0 2.6 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII DUF2039 PF10217.9 EPE36097.1 - 0.016 15.6 1.2 0.056 13.8 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Sen15 PF09631.10 EPE36098.1 - 2.3e-23 82.4 0.0 3.8e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Sen15 protein DUF2985 PF11204.8 EPE36099.1 - 1.9e-39 133.7 1.1 1.9e-39 133.7 1.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) EamA PF00892.20 EPE36100.1 - 4.7e-11 43.0 25.1 4.3e-06 27.0 3.1 3.2 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EPE36100.1 - 9.4e-09 34.9 0.4 9.4e-09 34.9 0.4 2.2 3 0 0 3 3 3 1 Nucleotide-sugar transporter TPT PF03151.16 EPE36100.1 - 0.0011 18.3 8.2 0.0041 16.5 1.0 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family MitoNEET_N PF10660.9 EPE36100.1 - 0.14 12.2 0.7 0.64 10.1 0.7 2.1 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus zf-C2H2 PF00096.26 EPE36101.1 - 8.4e-05 22.8 8.6 0.084 13.4 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPE36101.1 - 0.096 13.2 3.2 9.2 6.9 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPE36101.1 - 4.9 8.3 7.0 13 6.9 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Peptidase_C2 PF00648.21 EPE36102.1 - 4.6e-32 111.2 0.0 6.8e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EPE36102.1 - 1.1e-10 41.9 0.0 6.7e-07 29.7 0.0 3.6 2 1 0 2 2 2 2 Calpain large subunit, domain III MIT PF04212.18 EPE36102.1 - 0.00022 21.2 3.5 0.00033 20.6 3.5 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Mito_carr PF00153.27 EPE36103.1 - 7.1e-54 179.7 0.6 4.8e-19 68.1 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EPE36103.1 - 0.16 11.1 0.1 0.74 8.9 0.0 2.0 2 0 0 2 2 2 0 Gammaproteobacterial serine protease SAM_2 PF07647.17 EPE36104.1 - 5e-09 36.1 0.0 9.2e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EPE36104.1 - 8e-05 23.0 0.1 0.00016 22.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 EPE36104.1 - 0.092 12.9 0.1 0.25 11.4 0.1 1.7 2 0 0 2 2 2 0 IGR protein motif DUF4508 PF14969.6 EPE36104.1 - 0.16 12.2 0.5 0.33 11.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) TPR_19 PF14559.6 EPE36105.1 - 0.0017 18.8 0.0 1.4 9.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EPE36105.1 - 0.0072 16.5 1.8 2.1 8.8 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EPE36105.1 - 0.022 14.6 0.3 13 5.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 EPE36105.1 - 0.092 11.6 2.2 0.32 9.8 0.0 2.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 EPE36105.1 - 0.099 12.8 2.5 0.37 11.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPE36105.1 - 0.13 13.2 7.5 5.6 8.1 0.0 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EPE36106.1 - 4.3e-15 54.8 16.3 1.8e-05 24.4 0.4 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EPE36106.1 - 3.5e-14 52.8 17.5 1.3e-05 25.4 0.9 4.7 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EPE36106.1 - 5.5e-11 41.7 15.6 0.0035 17.3 0.4 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EPE36106.1 - 1e-10 40.9 10.3 0.00088 19.3 0.1 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EPE36106.1 - 3.1e-07 30.9 0.2 0.58 10.9 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EPE36106.1 - 8.7e-07 28.6 6.6 0.0031 17.4 0.3 4.9 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EPE36106.1 - 2.8e-06 27.7 9.1 0.03 14.8 0.2 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EPE36106.1 - 2.4e-05 23.9 2.6 1.9 8.2 0.5 3.9 3 0 0 3 3 3 2 TPR repeat TPR_6 PF13174.6 EPE36106.1 - 3.7e-05 24.1 3.5 0.0073 16.9 0.1 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EPE36106.1 - 0.00011 22.3 8.6 0.0038 17.5 0.2 5.2 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPE36106.1 - 0.00012 22.6 5.9 6.5 7.9 0.1 5.7 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EPE36106.1 - 0.0015 17.9 4.5 0.15 11.4 0.8 2.9 3 0 0 3 3 3 2 MalT-like TPR region TPR_15 PF13429.6 EPE36106.1 - 0.016 14.4 4.0 2.1 7.5 0.1 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE36106.1 - 0.38 11.0 7.4 11 6.4 0.2 4.6 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EPE36106.1 - 0.4 10.6 10.8 7.3 6.6 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SPRY PF00622.28 EPE36107.1 - 6e-22 78.0 0.0 1.1e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 SPRY domain Peptidase_C12 PF01088.21 EPE36108.1 - 6.1e-69 232.0 0.8 8.6e-69 231.5 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EPE36108.1 - 4.8e-09 36.0 0.1 4.8e-09 36.0 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases Zn_clus PF00172.18 EPE36109.1 - 6.6e-08 32.6 14.5 1e-07 31.9 14.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE36109.1 - 7.2e-07 28.3 0.8 7.2e-07 28.3 0.8 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain PLD_C PF12357.8 EPE36109.1 - 0.035 14.0 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase D C terminal MIP-T3_C PF17749.1 EPE36109.1 - 0.14 12.1 1.0 0.25 11.3 1.0 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region HEAT_EZ PF13513.6 EPE36110.1 - 3.3e-37 126.4 9.6 6.2e-16 58.5 0.0 11.8 10 2 2 12 12 12 6 HEAT-like repeat HEAT PF02985.22 EPE36110.1 - 1.8e-30 102.4 3.6 2e-05 24.4 0.0 10.3 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.6 EPE36110.1 - 1.2e-18 67.3 0.0 1.1e-05 25.7 0.0 7.1 4 2 3 7 7 7 3 HEAT repeats Vac14_Fab1_bd PF12755.7 EPE36110.1 - 2.2e-08 34.6 0.1 1.4 9.5 0.0 6.8 5 1 2 7 7 7 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EPE36110.1 - 4.9e-08 33.2 0.0 0.6 10.1 0.0 4.7 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EPE36110.1 - 8e-07 28.5 2.6 0.85 8.7 0.0 5.4 5 0 0 5 5 5 1 RNAPII transcription regulator C-terminal IBN_N PF03810.19 EPE36110.1 - 1.9e-06 27.7 0.0 6.8e-05 22.7 0.0 3.3 2 1 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.23 EPE36110.1 - 6.5e-05 22.8 2.5 0.3 11.2 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EPE36110.1 - 0.00014 20.6 0.0 0.44 9.0 0.0 3.7 3 0 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 EPE36110.1 - 0.001 18.7 0.1 5.4 6.5 0.0 5.6 6 1 1 7 7 7 1 CLASP N terminal RIX1 PF08167.12 EPE36110.1 - 0.0079 15.9 2.6 16 5.2 0.1 5.6 5 3 2 7 7 7 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.16 EPE36110.1 - 0.03 15.0 1.2 25 5.9 0.0 4.5 3 0 0 3 3 2 0 PBS lyase HEAT-like repeat DUF3437 PF11919.8 EPE36110.1 - 0.031 14.2 0.1 6.2 6.8 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) RTP1_C1 PF10363.9 EPE36110.1 - 0.042 14.0 0.1 9.7 6.4 0.0 3.9 5 0 0 5 5 4 0 Required for nuclear transport of RNA pol II C-terminus 1 TAF6_C PF07571.13 EPE36110.1 - 0.14 12.5 0.0 30 5.0 0.0 3.6 3 1 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain HBS1_N PF08938.10 EPE36110.1 - 0.25 11.7 2.8 4 7.8 3.7 2.6 2 0 0 2 2 2 0 HBS1 N-terminus PAC4 PF16093.5 EPE36111.1 - 3.6e-25 87.9 0.4 4.7e-25 87.6 0.4 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Abhydrolase_1 PF00561.20 EPE36112.1 - 1.4e-10 41.3 0.0 2.2e-10 40.6 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE36112.1 - 0.012 16.3 0.0 0.016 15.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE36112.1 - 0.058 12.6 0.0 0.43 9.8 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Flavin_Reduct PF01613.18 EPE36113.1 - 1.6e-16 60.8 0.0 2.1e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain adh_short_C2 PF13561.6 EPE36114.1 - 1.8e-45 155.3 0.2 2.4e-45 154.9 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE36114.1 - 1.3e-41 142.2 0.4 2e-41 141.6 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EPE36114.1 - 5.1e-12 46.1 0.2 7.3e-12 45.6 0.2 1.3 1 0 0 1 1 1 1 KR domain N2227 PF07942.12 EPE36115.1 - 4.3e-96 321.3 0.0 5.3e-96 321.0 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 EPE36115.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE36115.1 - 0.0004 21.1 0.1 0.0024 18.6 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE36115.1 - 0.0012 19.4 0.0 0.0033 18.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE36115.1 - 0.026 14.3 0.0 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DREV PF05219.12 EPE36115.1 - 0.032 13.3 0.0 0.07 12.2 0.0 1.5 1 1 0 1 1 1 0 DREV methyltransferase PAP_central PF04928.17 EPE36116.1 - 2.3e-109 364.2 0.0 3.1e-109 363.8 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EPE36116.1 - 5.4e-59 198.7 1.1 5.4e-59 198.7 1.1 1.9 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EPE36116.1 - 3.8e-09 36.7 0.0 1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EPE36116.1 - 0.034 14.2 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF2183 PF09949.9 EPE36117.1 - 1.2e-32 112.2 0.0 4.5e-32 110.3 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) CarboxypepD_reg PF13620.6 EPE36117.1 - 0.062 13.6 0.1 0.4 11.0 0.1 2.2 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain LapA_dom PF06305.11 EPE36118.1 - 0.00027 20.7 0.0 0.00054 19.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain Mid2 PF04478.12 EPE36118.1 - 0.0017 18.2 0.4 0.0028 17.5 0.4 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor CD34_antigen PF06365.12 EPE36118.1 - 0.027 14.1 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4381 PF14316.6 EPE36118.1 - 0.097 12.9 0.3 0.17 12.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) EphA2_TM PF14575.6 EPE36118.1 - 0.12 13.2 0.0 0.24 12.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MGC-24 PF05283.11 EPE36118.1 - 8.4 6.8 7.8 1.7 9.1 2.1 2.3 1 1 1 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Zn_clus PF00172.18 EPE36119.1 - 4.6e-07 29.9 8.4 4.6e-07 29.9 8.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE36119.1 - 1.3e-05 24.2 0.0 2.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4045 PF13254.6 EPE36120.1 - 1.6e-113 380.5 43.8 8.2e-73 246.4 29.0 5.3 3 2 2 5 5 5 2 Domain of unknown function (DUF4045) Gelsolin PF00626.22 EPE36120.1 - 7.7e-12 45.0 0.0 0.00014 21.6 0.0 3.6 3 0 0 3 3 3 2 Gelsolin repeat Arf PF00025.21 EPE36121.1 - 8.2e-51 171.9 0.4 9.1e-51 171.8 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EPE36121.1 - 5.9e-11 42.2 0.0 7e-11 42.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE36121.1 - 1.4e-07 31.8 0.0 1.9e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EPE36121.1 - 5e-07 29.2 0.1 8.1e-07 28.5 0.1 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.12 EPE36121.1 - 1.3e-06 28.0 0.0 1.3e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EPE36121.1 - 0.0018 17.8 0.0 0.0032 17.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EPE36121.1 - 0.0089 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 EPE36121.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.10 EPE36121.1 - 0.021 14.2 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Acetyltransf_1 PF00583.25 EPE36122.1 - 0.00022 21.4 0.0 0.00045 20.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE36122.1 - 0.0022 18.4 0.0 0.0055 17.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EPE36122.1 - 0.076 13.1 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DEAD PF00270.29 EPE36123.1 - 1e-45 155.7 0.0 2e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE36123.1 - 1.8e-28 99.1 0.0 2.6e-27 95.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EPE36123.1 - 0.0013 17.6 0.5 0.027 13.3 0.1 2.9 1 1 2 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Cupin_1 PF00190.22 EPE36124.1 - 3.7e-38 130.5 0.0 9.4e-18 64.3 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EPE36124.1 - 2.2e-25 88.1 1.4 3.9e-12 45.7 0.0 2.2 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 EPE36124.1 - 1.7e-10 40.9 0.3 6.6e-06 26.1 0.2 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain Ectoine_synth PF06339.12 EPE36124.1 - 4.2e-06 27.0 0.1 0.1 12.8 0.0 2.2 2 0 0 2 2 2 2 Ectoine synthase CENP-C_C PF11699.8 EPE36124.1 - 0.00015 21.9 0.0 0.19 12.0 0.0 2.3 2 0 0 2 2 2 2 Mif2/CENP-C like MannoseP_isomer PF01050.18 EPE36124.1 - 0.00077 19.4 0.0 0.019 14.8 0.0 2.3 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_3 PF05899.12 EPE36124.1 - 0.001 18.7 0.0 0.87 9.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.7 EPE36124.1 - 0.012 15.4 0.0 0.091 12.5 0.0 2.0 2 0 0 2 2 2 0 Cupin GCD14_N PF14801.6 EPE36124.1 - 0.015 15.1 0.1 2.8 7.8 0.1 2.4 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term FdtA PF05523.11 EPE36124.1 - 0.018 14.7 0.0 0.046 13.5 0.0 1.6 2 0 0 2 2 2 0 WxcM-like, C-terminal DUF1971 PF09313.11 EPE36124.1 - 0.041 13.9 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1971) 3-HAO PF06052.12 EPE36124.1 - 0.05 13.3 0.0 3.6 7.2 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase ARD PF03079.14 EPE36124.1 - 0.055 13.7 0.2 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 ARD/ARD' family DUF2347 PF09804.9 EPE36125.1 - 1.3e-101 340.0 0.0 1.8e-101 339.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 EPE36125.1 - 4.4e-61 206.6 0.3 2.2e-60 204.3 0.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 EPE36125.1 - 0.0037 16.0 0.0 0.056 12.1 0.0 2.2 2 1 0 2 2 2 1 Transport protein Avl9 SPA PF08616.10 EPE36125.1 - 0.02 14.8 0.0 0.071 13.1 0.0 1.8 1 1 0 1 1 1 0 Stabilization of polarity axis DnaJ PF00226.31 EPE36126.1 - 4.1e-16 58.8 0.6 1.4e-15 57.2 0.6 1.9 2 0 0 2 2 2 1 DnaJ domain Sec63 PF02889.16 EPE36126.1 - 7.5e-07 28.6 0.0 2.6e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Sec63 Brl domain SNF2_N PF00176.23 EPE36127.1 - 1.4e-60 204.8 0.0 2.2e-60 204.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPE36127.1 - 6.5e-14 52.2 0.0 1.4e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE36127.1 - 1.4e-12 48.0 0.0 3.1e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EPE36127.1 - 0.029 13.5 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 FliX PF10768.9 EPE36127.1 - 0.13 12.8 0.2 1.1 9.8 0.0 2.3 2 0 0 2 2 2 0 Class II flagellar assembly regulator BP28CT PF08146.12 EPE36128.1 - 3.3e-45 153.8 0.5 3.3e-45 153.8 0.5 2.4 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EPE36128.1 - 2.2e-29 102.2 0.6 2.2e-29 102.2 0.6 5.2 7 1 0 7 7 7 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 EPE36128.1 - 2.3e-05 24.3 8.2 0.063 13.6 0.2 5.0 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EPE36128.1 - 7.7e-05 23.0 13.2 0.21 12.0 0.1 6.5 6 1 1 7 7 7 2 HEAT repeats CLASP_N PF12348.8 EPE36128.1 - 0.042 13.4 3.4 7.7 6.0 0.0 4.6 6 0 0 6 6 6 0 CLASP N terminal TetR_C_31 PF17940.1 EPE36128.1 - 0.069 13.4 0.6 0.52 10.5 0.2 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain 8TM_micro PF17028.5 EPE36128.1 - 0.096 12.4 0.3 0.2 11.3 0.3 1.5 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain HEAT_EZ PF13513.6 EPE36128.1 - 0.21 12.1 15.8 6.1 7.5 0.2 7.6 7 1 0 7 7 7 0 HEAT-like repeat RTP1_C1 PF10363.9 EPE36128.1 - 1.5 9.1 7.9 2.7 8.2 0.0 4.7 6 0 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 NRDE-2 PF08424.10 EPE36129.1 - 1.1e-97 327.1 2.4 8e-97 324.2 0.4 2.8 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EPE36129.1 - 0.002 18.8 0.7 6.3 7.9 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Peptidase_M24 PF00557.24 EPE36130.1 - 1.8e-58 197.7 0.1 2.7e-58 197.1 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EPE36130.1 - 1.1e-15 57.4 0.0 2.2e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RPN7 PF10602.9 EPE36131.1 - 1.7e-50 171.1 0.0 2.6e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EPE36131.1 - 5.8e-10 39.6 0.0 1.6e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 PCI domain SWIRM-assoc_3 PF16498.5 EPE36131.1 - 0.0061 16.8 0.1 0.029 14.6 0.1 2.0 2 0 0 2 2 2 1 SWIRM-associated domain at the C-terminal TPR_2 PF07719.17 EPE36131.1 - 0.039 14.1 1.1 2.5 8.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 EPE36132.1 - 4.4e-19 68.5 0.0 7.4e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE36132.1 - 2.3e-11 43.6 12.6 3.9e-11 42.9 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 EPE36132.1 - 0.04 14.1 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 Gal4-like dimerisation domain Sulfotransfer_3 PF13469.6 EPE36133.1 - 0.0035 17.7 0.0 0.098 13.0 0.0 2.6 1 1 0 1 1 1 1 Sulfotransferase family UCMA PF17085.5 EPE36133.1 - 0.2 11.7 1.6 0.28 11.2 0.4 1.8 1 1 0 1 1 1 0 Unique cartilage matrix associated protein Mhr1 PF12829.7 EPE36134.1 - 5e-33 113.1 0.4 1.2e-32 111.8 0.4 1.7 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination AAA_2 PF07724.14 EPE36135.1 - 5.6e-47 160.0 0.0 4.1e-46 157.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EPE36135.1 - 4.3e-33 113.4 1.3 4.3e-33 113.4 1.3 3.1 3 0 0 3 3 2 1 AAA lid domain AAA PF00004.29 EPE36135.1 - 5.2e-28 98.1 0.0 3.9e-14 53.2 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EPE36135.1 - 5.5e-23 80.8 0.1 1.9e-22 79.1 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EPE36135.1 - 4.9e-15 55.7 0.0 1.1e-09 38.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPE36135.1 - 4.9e-13 49.8 6.7 5.8e-06 26.8 0.0 5.1 4 2 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 EPE36135.1 - 3.4e-12 46.8 0.2 0.00012 22.4 0.0 4.2 2 2 1 3 3 2 2 AAA domain Sigma54_activat PF00158.26 EPE36135.1 - 1.2e-08 34.8 0.0 1.3e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 EPE36135.1 - 1.2e-06 28.1 0.0 0.0075 15.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 EPE36135.1 - 3.4e-06 27.6 0.2 0.089 13.3 0.0 3.6 2 1 1 3 3 3 2 AAA domain Mg_chelatase PF01078.21 EPE36135.1 - 3.5e-06 26.6 0.1 0.071 12.5 0.1 3.5 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EPE36135.1 - 8.3e-06 25.6 0.0 0.1 12.3 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase_2 PF01637.18 EPE36135.1 - 9.7e-06 25.7 1.3 0.027 14.4 0.1 4.7 4 1 0 4 4 4 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 EPE36135.1 - 1e-05 25.7 0.8 0.072 13.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 EPE36135.1 - 2.7e-05 24.2 0.0 0.27 11.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain Clp_N PF02861.20 EPE36135.1 - 2.8e-05 24.2 0.2 0.092 12.9 0.0 3.7 3 0 0 3 3 2 1 Clp amino terminal domain, pathogenicity island component AAA_28 PF13521.6 EPE36135.1 - 4.7e-05 23.7 0.1 0.48 10.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain TniB PF05621.11 EPE36135.1 - 6.9e-05 22.3 0.8 1.4 8.3 0.1 4.3 4 1 0 4 4 3 1 Bacterial TniB protein AAA_3 PF07726.11 EPE36135.1 - 8.9e-05 22.4 0.0 1.2 8.9 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EPE36135.1 - 9.6e-05 22.7 0.0 0.64 10.4 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 EPE36135.1 - 9.7e-05 22.2 0.0 0.69 9.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EPE36135.1 - 0.00018 21.8 0.1 0.061 13.7 0.1 3.4 4 1 0 4 4 2 1 AAA domain RsgA_GTPase PF03193.16 EPE36135.1 - 0.00021 21.2 0.0 0.27 11.1 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase RuvB_N PF05496.12 EPE36135.1 - 0.00021 21.0 0.8 4.5 7.0 0.6 4.2 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 EPE36135.1 - 0.00037 21.0 0.0 0.92 10.0 0.0 3.3 2 1 0 2 2 2 1 ABC transporter TsaE PF02367.17 EPE36135.1 - 0.00049 20.1 0.0 0.6 10.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EPE36135.1 - 0.00066 19.5 0.0 0.72 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Torsin PF06309.11 EPE36135.1 - 0.001 19.2 0.0 0.0047 17.0 0.0 2.0 2 0 0 2 2 2 1 Torsin TIP49 PF06068.13 EPE36135.1 - 0.0018 17.6 0.1 0.27 10.4 0.0 2.9 2 1 1 3 3 3 1 TIP49 P-loop domain ResIII PF04851.15 EPE36135.1 - 0.0024 17.9 0.0 0.88 9.5 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_29 PF13555.6 EPE36135.1 - 0.0025 17.5 0.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 EPE36135.1 - 0.0034 16.5 0.0 0.064 12.3 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Rad17 PF03215.15 EPE36135.1 - 0.0052 16.7 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Roc PF08477.13 EPE36135.1 - 0.0076 16.5 0.0 1.9 8.8 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EPE36135.1 - 0.0086 16.0 0.0 0.56 10.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 EPE36135.1 - 0.013 14.8 0.0 2.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 EPE36135.1 - 0.017 15.0 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 0 NTPase SRP54 PF00448.22 EPE36135.1 - 0.023 14.3 0.0 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 EPE36135.1 - 0.026 14.3 13.7 3.9 7.2 0.0 4.5 3 2 1 4 4 3 0 AAA domain DUF815 PF05673.13 EPE36135.1 - 0.029 13.5 0.0 4.3 6.4 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 EPE36135.1 - 0.059 13.1 0.0 15 5.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.6 EPE36135.1 - 0.072 12.9 0.0 26 4.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 EPE36135.1 - 0.12 12.1 0.0 6.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Apt1 PF10351.9 EPE36135.1 - 0.36 9.6 2.3 0.72 8.6 2.3 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain AAA_25 PF13481.6 EPE36135.1 - 0.61 9.6 3.8 19 4.7 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EPE36135.1 - 1.5 9.2 16.0 0.41 11.1 0.2 4.4 2 1 2 4 4 4 0 AAA domain Cep57_CLD_2 PF14197.6 EPE36135.1 - 1.7 8.8 6.6 7.2 6.8 6.6 2.2 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ABC_tran PF00005.27 EPE36137.1 - 3e-45 154.1 0.0 5.3e-28 98.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 EPE36137.1 - 1.2e-38 133.4 21.2 1.7e-19 70.6 11.0 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 EPE36137.1 - 4.1e-14 52.5 0.0 3.8e-08 33.0 0.0 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EPE36137.1 - 4.9e-08 33.1 0.2 0.11 12.3 0.0 4.3 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EPE36137.1 - 5.7e-07 29.9 0.1 0.0015 18.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EPE36137.1 - 7.1e-05 23.2 0.0 0.022 15.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EPE36137.1 - 0.00051 20.0 0.0 0.39 10.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 EPE36137.1 - 0.00073 19.2 2.4 0.047 13.3 0.4 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EPE36137.1 - 0.0012 19.4 0.6 0.081 13.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EPE36137.1 - 0.0018 18.0 5.1 0.12 12.1 1.2 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA PF00004.29 EPE36137.1 - 0.0059 17.0 0.2 2.9 8.3 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EPE36137.1 - 0.035 14.2 0.1 1.6 8.8 0.1 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 EPE36137.1 - 0.037 13.9 0.1 0.46 10.4 0.0 2.4 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EPE36137.1 - 0.042 13.4 0.5 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 EPE36137.1 - 0.069 13.1 0.1 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 NACHT domain T2SSE PF00437.20 EPE36137.1 - 0.11 11.5 0.9 3.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_ATPase PF09818.9 EPE36137.1 - 4 6.1 5.8 14 4.3 0.2 3.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class SKG6 PF08693.10 EPE36139.1 - 0.0004 19.7 1.5 0.0004 19.7 1.5 2.0 3 0 0 3 3 3 1 Transmembrane alpha-helix domain CFEM PF05730.11 EPE36139.1 - 0.001 19.1 1.6 0.0022 18.0 1.6 1.5 1 0 0 1 1 1 1 CFEM domain FmiP_Thoc5 PF09766.9 EPE36139.1 - 0.062 12.6 1.1 0.13 11.6 1.1 1.4 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 ATG16 PF08614.11 EPE36139.1 - 0.12 12.6 5.2 0.25 11.5 5.2 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) His_Phos_2 PF00328.22 EPE36140.1 - 2.9e-20 73.0 0.0 8.3e-20 71.5 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) FAD_binding_3 PF01494.19 EPE36141.1 - 2e-11 43.8 0.0 4.9e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EPE36141.1 - 1.1e-07 31.3 0.1 1.9e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE36141.1 - 1.7e-06 27.5 0.1 0.00013 21.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE36141.1 - 1.4e-05 25.2 0.4 7.7e-05 22.9 0.1 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EPE36141.1 - 2.6e-05 23.1 0.1 9.7e-05 21.2 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EPE36141.1 - 4.3e-05 23.3 0.4 0.007 16.0 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EPE36141.1 - 0.00024 20.6 0.1 0.00045 19.7 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EPE36141.1 - 0.0017 17.5 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EPE36141.1 - 0.0022 18.5 0.8 0.095 13.3 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE36141.1 - 0.0039 16.5 0.1 0.0076 15.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EPE36141.1 - 0.026 13.8 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EPE36141.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pkinase PF00069.25 EPE36142.1 - 2.3e-11 43.6 0.0 1.2e-10 41.2 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE36142.1 - 0.00037 19.9 0.0 0.0016 17.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase NmrA PF05368.13 EPE36143.1 - 1.6e-12 47.5 0.0 1e-11 44.9 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE36143.1 - 2.8e-10 40.4 0.0 2.2e-09 37.5 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE36143.1 - 8.1e-06 25.5 0.0 0.0094 15.4 0.0 3.1 1 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family TraH_2 PF06871.11 EPE36143.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 TraH_2 F420_oxidored PF03807.17 EPE36143.1 - 0.094 13.3 0.0 0.23 12.1 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EPE36143.1 - 0.12 11.7 0.0 0.4 10.0 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 EPE36144.1 - 2.9e-57 194.2 1.2 4.1e-57 193.8 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE36144.1 - 1.9e-09 37.4 9.3 3.4e-09 36.7 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG22 PF11700.8 EPE36145.1 - 6.2e-129 430.7 18.4 7.1e-129 430.5 18.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EPE36145.1 - 1.1e-14 54.1 30.1 1e-06 27.9 9.7 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF2684 PF10885.8 EPE36145.1 - 0.66 10.1 5.3 0.28 11.3 1.6 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2684) DUF917 PF06032.12 EPE36146.1 - 3.5e-101 338.5 0.0 6.6e-101 337.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 EPE36146.1 - 8.1e-35 120.1 0.4 6.9e-31 107.3 0.0 2.8 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 EPE36146.1 - 1.9e-26 93.0 6.2 6e-23 81.5 0.2 3.2 2 1 0 3 3 3 3 Hydantoinase/oxoprolinase MutL PF13941.6 EPE36146.1 - 6.8e-08 31.5 0.7 0.00046 18.9 0.0 2.4 2 0 0 2 2 2 2 MutL protein FtsA PF14450.6 EPE36146.1 - 0.00043 20.6 1.1 0.031 14.7 0.0 3.1 3 0 0 3 3 3 1 Cell division protein FtsA ROK PF00480.20 EPE36146.1 - 0.00078 19.0 0.6 0.0021 17.6 0.6 1.7 1 0 0 1 1 1 1 ROK family StbA PF06406.11 EPE36146.1 - 0.0027 17.0 2.3 0.63 9.2 0.1 2.9 3 0 0 3 3 3 2 StbA protein BcrAD_BadFG PF01869.20 EPE36146.1 - 0.031 13.8 0.3 0.031 13.8 0.3 2.5 3 0 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family CNH PF00780.22 EPE36147.1 - 6.2e-15 55.5 0.0 1.6e-14 54.2 0.0 1.7 1 1 0 1 1 1 1 CNH domain MID_MedPIWI PF18296.1 EPE36147.1 - 0.038 13.8 0.6 0.091 12.5 0.6 1.6 1 0 0 1 1 1 0 MID domain of medPIWI zf-C2H2_6 PF13912.6 EPE36147.1 - 0.51 10.4 6.2 0.17 11.9 0.3 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EPE36147.1 - 4.1 8.5 25.0 0.25 12.3 0.7 5.3 5 0 0 5 5 5 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPE36147.1 - 5 7.7 8.0 12 6.5 0.8 3.4 2 1 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.26 EPE36147.1 - 5.9 7.5 16.9 11 6.8 0.2 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type dCache_1 PF02743.18 EPE36148.1 - 0.062 13.1 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Cache domain AAA PF00004.29 EPE36149.1 - 1.1e-47 161.7 0.0 3.2e-42 144.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPE36149.1 - 2.2e-10 40.1 0.0 5.6e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 EPE36149.1 - 2.2e-07 30.8 0.0 4.5e-05 23.3 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_2 PF07724.14 EPE36149.1 - 1.8e-05 24.9 0.0 5.1e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EPE36149.1 - 4e-05 23.6 0.0 0.00027 21.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPE36149.1 - 6.3e-05 23.4 0.1 0.0014 19.1 0.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EPE36149.1 - 0.00011 22.5 0.0 0.029 14.6 0.2 3.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EPE36149.1 - 0.0016 18.8 0.0 0.011 16.1 0.0 2.3 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.12 EPE36149.1 - 0.0038 17.0 0.0 0.03 14.1 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EPE36149.1 - 0.01 16.4 0.2 0.078 13.5 0.0 2.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EPE36149.1 - 0.013 15.1 0.0 0.045 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EPE36149.1 - 0.015 15.5 0.0 0.045 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Bromodomain PF00439.25 EPE36149.1 - 0.017 15.2 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 Bromodomain AAA_33 PF13671.6 EPE36149.1 - 0.018 15.2 0.0 0.086 13.0 0.0 2.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EPE36149.1 - 0.018 14.4 0.1 0.061 12.7 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 EPE36149.1 - 0.035 14.2 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain TIP49 PF06068.13 EPE36149.1 - 0.035 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 EPE36149.1 - 0.036 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EPE36149.1 - 0.036 14.6 0.0 0.63 10.6 0.0 2.8 2 0 0 2 2 2 0 ABC transporter Parvo_NS1 PF01057.17 EPE36149.1 - 0.047 12.8 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 EPE36149.1 - 0.057 13.1 0.0 4.2 7.0 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EPE36149.1 - 0.06 13.2 0.3 1.7 8.5 0.0 3.6 5 1 0 5 5 3 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EPE36149.1 - 0.06 13.1 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EPE36149.1 - 0.1 12.1 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 EPE36149.1 - 0.14 12.1 0.0 0.45 10.4 0.0 1.9 2 0 0 2 2 1 0 NACHT domain PhoH PF02562.16 EPE36149.1 - 0.14 11.6 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein CorA PF01544.18 EPE36150.1 - 0.29 10.4 9.2 1.9 7.7 9.2 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein LMBR1 PF04791.16 EPE36152.1 - 3e-116 389.3 4.8 3.5e-116 389.1 4.8 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF148 PF02520.17 EPE36152.1 - 0.17 12.0 0.2 0.29 11.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 zf-C2H2 PF00096.26 EPE36153.1 - 3.9e-29 99.5 53.0 2.6e-05 24.4 0.1 10.6 11 0 0 11 11 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE36153.1 - 7.4e-19 66.8 47.2 0.11 13.3 0.1 11.2 11 0 0 11 11 11 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE36153.1 - 4.6e-14 52.3 30.1 0.04 14.2 0.2 9.6 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EPE36153.1 - 6.7e-11 42.1 51.3 0.011 16.1 0.8 11.1 11 1 0 11 11 11 5 Zinc-finger double domain zf-met PF12874.7 EPE36153.1 - 1.7e-08 34.5 19.8 0.12 12.8 0.1 8.1 9 0 0 9 9 9 3 Zinc-finger of C2H2 type FOXP-CC PF16159.5 EPE36153.1 - 3.1e-07 30.9 25.5 0.085 13.5 0.8 8.1 6 2 4 10 10 10 3 FOXP coiled-coil domain zf-Di19 PF05605.12 EPE36153.1 - 4.6e-06 26.8 34.2 0.14 12.5 0.4 7.7 5 3 3 8 8 7 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 EPE36153.1 - 0.0007 19.8 13.6 0.29 11.5 0.1 3.8 3 1 2 5 5 4 3 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 EPE36153.1 - 0.006 17.3 8.6 0.23 12.2 0.0 4.8 3 1 2 5 5 5 1 Zinc finger C2H2-type, 3 repeats DUF4187 PF13821.6 EPE36153.1 - 0.017 14.9 2.8 0.027 14.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) zf-C2H2_aberr PF17017.5 EPE36153.1 - 0.022 14.9 21.0 5.6 7.1 5.2 6.6 2 1 6 8 8 8 0 Aberrant zinc-finger zf_ZIC PF18366.1 EPE36153.1 - 0.049 13.7 10.2 19 5.4 0.0 6.6 9 1 0 9 9 9 0 Zic proteins zinc finger domain zf_Hakai PF18408.1 EPE36153.1 - 1.6 8.5 0.0 1.6 8.5 0.0 7.8 9 0 0 9 9 9 0 C2H2 Hakai zinc finger domain zf-C2H2_6 PF13912.6 EPE36153.1 - 2 8.5 17.0 35 4.5 0.2 6.9 7 0 0 7 7 7 0 C2H2-type zinc finger RNA_pol_Rpb6 PF01192.22 EPE36154.1 - 3.5e-16 58.9 0.7 5.7e-16 58.2 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.12 EPE36154.1 - 0.011 15.7 0.3 0.016 15.2 0.3 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Ku_C PF03730.14 EPE36154.1 - 0.47 11.2 3.7 1.4 9.6 2.2 2.0 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm Esterase PF00756.20 EPE36155.1 - 2.8e-49 168.0 0.0 3.4e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 EPE36155.1 - 0.00027 20.5 0.0 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 EPE36155.1 - 0.00056 19.2 0.0 0.0039 16.5 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EPE36155.1 - 0.002 17.1 0.0 0.0057 15.6 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 EPE36155.1 - 0.0039 16.7 0.0 0.0076 15.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.25 EPE36155.1 - 0.034 14.0 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 EPE36155.1 - 0.066 11.9 0.0 0.096 11.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 EPE36155.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.7 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.18 EPE36155.1 - 0.18 11.3 0.3 0.43 10.1 0.3 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Afi1 PF07792.12 EPE36156.1 - 9.4e-47 158.8 0.4 1.6e-46 158.1 0.4 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 EPE36156.1 - 2.6e-37 127.3 0.0 4.9e-37 126.4 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 EPE36156.1 - 9.3e-08 31.2 0.0 0.015 14.0 0.0 3.8 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.9 EPE36156.1 - 0.046 13.3 0.0 0.24 11.0 0.0 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Cwf_Cwc_15 PF04889.12 EPE36156.1 - 0.046 13.5 4.3 0.1 12.3 3.9 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 EPE36156.1 - 0.39 10.7 4.7 0.7 9.8 4.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EF-hand_6 PF13405.6 EPE36157.1 - 1.3e-12 46.5 0.7 3e-06 26.7 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EPE36157.1 - 5.3e-10 38.1 1.7 0.00026 20.3 0.1 2.7 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EPE36157.1 - 4.2e-07 30.3 0.1 0.023 15.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EPE36157.1 - 6.5e-06 25.9 0.0 0.014 15.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EPE36157.1 - 1.8e-05 24.0 3.7 0.0024 17.3 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EPE36157.1 - 4.6e-05 23.7 0.0 0.012 15.9 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain Whi5 PF08528.11 EPE36158.1 - 3.3e-10 39.4 0.4 6.5e-10 38.4 0.2 1.6 2 0 0 2 2 2 1 Whi5 like Dynactin PF12455.8 EPE36158.1 - 0.094 11.9 0.3 0.18 11.0 0.2 1.5 2 0 0 2 2 2 0 Dynein associated protein KIX_2 PF16987.5 EPE36159.1 - 3.1e-07 30.3 0.0 3.1e-06 27.1 0.0 2.9 1 0 0 1 1 1 1 KIX domain Med15_fungi PF05397.12 EPE36159.1 - 5.5e-06 26.6 5.1 5.5e-06 26.6 5.1 7.5 8 0 0 8 8 8 1 Mediator complex subunit 15 SSF PF00474.17 EPE36160.1 - 3.5e-18 65.7 23.3 6e-18 64.9 23.3 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Pkinase PF00069.25 EPE36162.1 - 5.3e-28 98.1 0.0 3.3e-27 95.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE36162.1 - 0.00014 21.2 0.0 0.23 10.7 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Methyltransf_16 PF10294.9 EPE36163.1 - 1.9e-13 50.5 0.0 2.8e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 EPE36163.1 - 0.2 11.3 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 zf-C2H2 PF00096.26 EPE36164.1 - 5.9e-05 23.3 16.7 1.2 9.8 0.5 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-met PF12874.7 EPE36164.1 - 0.038 14.4 1.5 2.5 8.6 0.6 3.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EPE36164.1 - 0.12 12.4 1.1 5.7 7.0 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 EPE36164.1 - 0.14 12.8 5.6 0.84 10.3 0.6 3.3 3 0 0 3 3 3 0 FOXP coiled-coil domain Pox_G9-A16 PF03003.16 EPE36164.1 - 0.18 11.5 0.5 0.36 10.5 0.5 1.4 1 0 0 1 1 1 0 Pox virus entry-fusion-complex G9/A16 zf-TAZ PF02135.16 EPE36164.1 - 0.39 11.2 5.3 0.43 11.1 2.8 2.1 2 0 0 2 2 2 0 TAZ zinc finger zf-C2H2_jaz PF12171.8 EPE36164.1 - 0.49 10.8 7.0 4 7.8 0.8 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EPE36164.1 - 1.9 9.6 21.7 1.3 10.1 0.3 5.2 5 1 0 5 5 5 0 C2H2-type zinc finger HRXXH PF13933.6 EPE36165.1 - 0.00013 21.6 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family zf-rbx1 PF12678.7 EPE36166.1 - 4.2e-08 33.4 5.7 2.5e-07 30.9 5.7 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EPE36166.1 - 1.1e-07 32.1 2.1 1.1e-07 32.1 2.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EPE36166.1 - 2.1e-05 24.3 0.6 6.4e-05 22.7 0.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE36166.1 - 4.4e-05 23.3 2.2 0.00019 21.3 0.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EPE36166.1 - 5.5e-05 23.1 0.3 0.00021 21.3 0.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EPE36166.1 - 7.8e-05 22.5 4.0 0.00078 19.3 0.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EPE36166.1 - 0.0011 18.6 0.7 0.0025 17.4 0.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EPE36166.1 - 0.0015 18.3 2.4 0.0015 18.3 2.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPE36166.1 - 0.0027 17.5 0.9 0.0027 17.5 0.9 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EPE36166.1 - 0.0086 16.1 1.8 0.044 13.8 0.5 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EPE36166.1 - 0.073 13.2 0.8 0.2 11.9 0.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SieB PF14163.6 EPE36166.1 - 0.075 12.5 0.2 0.17 11.4 0.2 1.5 1 0 0 1 1 1 0 Super-infection exclusion protein B zf-RING_4 PF14570.6 EPE36166.1 - 1.9 8.4 3.2 1 9.2 0.8 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Glyco_transf_8 PF01501.20 EPE36167.1 - 1.1e-22 80.9 1.2 2.3e-21 76.5 1.2 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EPE36167.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Mannosyltransferase putative PDEase_II PF02112.15 EPE36169.1 - 2e-50 171.8 0.0 5.4e-26 91.5 0.0 2.5 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II AMP-binding PF00501.28 EPE36170.1 - 3.9e-63 213.5 0.8 9.7e-26 90.3 0.9 4.3 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.11 EPE36170.1 - 2.9e-11 44.1 0.4 7.7e-11 42.8 0.4 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 EPE36170.1 - 6.2 6.9 8.9 0.044 13.8 0.5 1.8 2 0 0 2 2 2 0 Gas vesicle protein G Tma16 PF11176.8 EPE36172.1 - 0.08 12.8 0.8 0.2 11.5 0.8 1.6 1 0 0 1 1 1 0 Translation machinery-associated protein 16 K_oxygenase PF13434.6 EPE36173.1 - 1.8e-15 56.9 0.0 1.6e-09 37.4 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EPE36173.1 - 4.4e-08 32.7 0.5 0.03 13.6 0.1 3.6 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPE36173.1 - 6.1e-08 32.2 0.0 0.4 9.9 0.0 3.2 2 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE36173.1 - 9.1e-08 32.1 3.1 0.012 15.3 0.0 3.6 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EPE36173.1 - 6.2e-05 23.0 0.0 0.046 13.7 0.0 3.6 4 1 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 EPE36173.1 - 0.0051 16.1 0.0 0.015 14.5 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 EPE36173.1 - 0.0065 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPE36173.1 - 0.066 13.5 0.0 0.47 10.7 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EPE36173.1 - 0.14 10.8 0.0 0.61 8.7 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 EPE36173.1 - 0.15 12.7 0.1 15 6.2 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EPE36173.1 - 0.19 10.9 0.1 0.4 9.9 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Lactonase PF10282.9 EPE36174.1 - 1.2e-77 261.5 0.0 1.6e-77 261.1 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PS_Dcarbxylase PF02666.15 EPE36175.1 - 1.7e-77 259.5 0.0 8.1e-57 192.0 0.0 2.1 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase ubiquitin PF00240.23 EPE36176.1 - 2.2e-05 24.1 0.0 6.1e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EPE36176.1 - 9.9e-05 22.9 0.0 0.00025 21.6 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain CitMHS PF03600.16 EPE36176.1 - 0.031 13.5 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Citrate transporter YukD PF08817.10 EPE36176.1 - 0.15 12.7 0.5 1.3 9.7 0.0 2.5 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD PF11976.8 EPE36176.1 - 0.23 11.3 0.0 3.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Gtr1_RagA PF04670.12 EPE36177.1 - 2.2e-73 246.5 0.0 2.8e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EPE36177.1 - 0.0018 17.7 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EPE36177.1 - 0.0048 17.1 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EPE36177.1 - 0.052 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EPE36177.1 - 0.061 13.7 0.0 0.15 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain MIF PF01187.18 EPE36178.1 - 5.5e-11 42.8 0.0 8.4e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) BPD_transp_1 PF00528.22 EPE36179.1 - 0.022 14.5 5.8 0.093 12.5 0.7 2.5 2 1 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component LIFR_N PF18207.1 EPE36179.1 - 0.098 13.0 0.3 0.19 12.1 0.3 1.4 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor N-terminal domain PXA PF02194.15 EPE36180.1 - 2.3e-45 154.8 0.0 4.9e-45 153.7 0.0 1.6 1 0 0 1 1 1 1 PXA domain HTH_Tnp_Tc5 PF03221.16 EPE36181.1 - 5.6e-17 61.5 0.0 1.4e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EPE36181.1 - 4.3e-06 26.2 0.0 8.1e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.22 EPE36181.1 - 0.019 14.9 0.0 0.054 13.4 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.6 EPE36181.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_Tnp_4 PF13613.6 EPE36181.1 - 0.072 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MMR_HSR1_Xtn PF16897.5 EPE36182.1 - 4.1e-40 136.1 1.1 1.5e-39 134.3 0.4 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EPE36182.1 - 7.3e-22 77.2 0.2 1.7e-21 76.0 0.2 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EPE36182.1 - 1.1e-20 73.9 0.1 3e-20 72.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPE36182.1 - 8.1e-09 35.2 0.1 4e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EPE36182.1 - 0.00097 19.2 0.1 0.19 11.8 0.0 2.3 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 EPE36182.1 - 0.0016 18.0 0.1 9.4 5.7 0.0 3.5 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 EPE36182.1 - 0.0098 14.9 0.2 0.02 13.9 0.2 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EPE36182.1 - 0.11 12.3 1.0 3.8 7.4 0.1 2.7 3 0 0 3 3 3 0 RsgA GTPase Ploopntkinase3 PF18751.1 EPE36182.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 2OG-FeII_Oxy_2 PF13532.6 EPE36184.1 - 0.00031 21.0 0.0 0.00036 20.8 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1652 PF07865.11 EPE36184.1 - 0.19 11.6 0.0 0.55 10.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) Ank_2 PF12796.7 EPE36185.1 - 1.6e-20 73.4 0.2 8.1e-16 58.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE36185.1 - 6.8e-17 61.3 0.7 3.7e-07 30.3 0.0 4.3 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPE36185.1 - 1.2e-16 60.8 0.0 2.5e-10 40.6 0.0 5.1 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EPE36185.1 - 2.2e-11 43.7 0.1 0.00025 21.4 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EPE36185.1 - 1.2e-10 40.6 0.0 0.0072 16.8 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat His_Phos_1 PF00300.22 EPE36186.1 - 5.7e-16 58.8 0.0 7.7e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-Mss51 PF13824.6 EPE36187.1 - 8.8e-29 99.4 5.6 8.8e-29 99.4 5.6 1.8 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf_UBZ PF18439.1 EPE36187.1 - 0.19 11.3 4.9 4.7 6.9 1.3 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TPT PF03151.16 EPE36188.1 - 2.6e-07 30.3 22.3 4.9e-07 29.4 22.3 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family UPF0139 PF03669.13 EPE36188.1 - 0.077 12.9 0.2 0.24 11.3 0.2 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) Tuberculin PF12198.8 EPE36188.1 - 0.15 12.2 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Theoretical tuberculin protein Fungal_trans PF04082.18 EPE36192.1 - 8.2e-11 41.4 0.1 1.5e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE36192.1 - 4.4e-06 26.7 6.3 4.4e-06 26.7 6.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPE36193.1 - 1.3e-28 100.0 25.3 1.3e-28 100.0 25.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE36193.1 - 0.0013 17.7 10.0 0.0013 17.7 10.0 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter CreD PF06123.12 EPE36193.1 - 1.9 7.2 5.5 0.86 8.3 1.9 1.9 2 0 0 2 2 2 0 Inner membrane protein CreD Polysacc_deac_1 PF01522.21 EPE36194.1 - 1.1e-27 96.4 0.0 2e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase SH3_9 PF14604.6 EPE36194.1 - 9.2e-06 25.4 0.3 9.2e-06 25.4 0.3 1.9 2 0 0 2 2 2 1 Variant SH3 domain Chitin_bind_1 PF00187.19 EPE36194.1 - 1.7e-05 25.2 46.8 2.6e-05 24.6 21.3 3.2 3 0 0 3 3 3 2 Chitin recognition protein SH3_1 PF00018.28 EPE36194.1 - 5.9e-05 22.6 0.2 0.00014 21.4 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EPE36194.1 - 0.0031 17.1 0.1 0.009 15.7 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain Methyltransf_23 PF13489.6 EPE36195.1 - 2.5e-15 56.7 0.0 3.8e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE36195.1 - 7.9e-08 32.9 0.0 2.2e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE36195.1 - 5.8e-07 29.4 0.0 3.1e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE36195.1 - 1.5e-06 28.8 0.0 9.5e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EPE36195.1 - 2.2e-05 23.8 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_11 PF08241.12 EPE36195.1 - 0.0001 22.9 0.0 0.00026 21.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EPE36195.1 - 0.003 17.0 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.20 EPE36195.1 - 0.0067 15.8 0.0 0.0091 15.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EPE36195.1 - 0.032 13.8 0.0 0.07 12.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 EPE36195.1 - 0.038 13.3 0.0 0.22 10.8 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EPE36195.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase RgpF PF05045.12 EPE36198.1 - 0.0055 15.5 0.0 0.12 11.1 0.0 2.1 2 0 0 2 2 2 2 Rhamnan synthesis protein F XET_C PF06955.12 EPE36198.1 - 0.12 12.2 1.0 0.36 10.7 1.0 1.7 1 0 0 1 1 1 0 Xyloglucan endo-transglycosylase (XET) C-terminus Brix PF04427.18 EPE36199.1 - 3.3e-26 92.6 0.0 4.4e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain HGTP_anticodon PF03129.20 EPE36200.1 - 4.8e-19 68.3 2.1 1.6e-18 66.6 0.0 2.8 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EPE36200.1 - 1.5e-09 38.1 0.0 6.1e-07 29.6 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetase class II core domain (G, H, P, S and T) HTH_Tnp_Mu_1 PF02316.16 EPE36200.1 - 0.098 12.8 1.6 6.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Mu DNA-binding domain Macoilin PF09726.9 EPE36200.1 - 6.1 5.3 5.1 32 2.9 0.0 2.0 2 0 0 2 2 2 0 Macoilin family Pkinase PF00069.25 EPE36201.1 - 9.7e-69 231.7 1.8 1e-67 228.3 1.8 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE36201.1 - 4.7e-53 180.1 0.1 8.4e-53 179.3 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EPE36201.1 - 3e-24 85.1 0.6 7.8e-24 83.8 0.1 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.6 EPE36201.1 - 4.2e-06 26.3 0.0 7.1e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EPE36201.1 - 1.2e-05 24.3 0.0 1.2e-05 24.3 0.0 2.2 2 1 0 2 2 2 1 Fungal protein kinase PH_11 PF15413.6 EPE36201.1 - 2.1e-05 24.9 0.1 9.5e-05 22.8 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EPE36201.1 - 0.001 19.6 0.0 0.0028 18.2 0.0 1.8 1 0 0 1 1 1 1 PH domain APH PF01636.23 EPE36201.1 - 0.0037 17.2 3.7 0.014 15.3 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EPE36201.1 - 0.066 12.3 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EPE36201.1 - 1.6 7.6 5.4 0.16 10.9 0.4 1.9 2 1 0 2 2 2 0 Haspin like kinase domain Abhydrolase_6 PF12697.7 EPE36202.1 - 3.6e-11 44.1 1.0 4.5e-11 43.8 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Melibiase_2 PF16499.5 EPE36204.1 - 6e-61 206.1 11.9 3.9e-60 203.4 11.9 2.0 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EPE36204.1 - 7.8e-11 41.9 1.2 2e-08 34.2 0.4 2.6 2 0 0 2 2 2 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EPE36204.1 - 1e-06 28.0 0.1 2.1e-06 27.0 0.0 1.4 2 0 0 2 2 2 1 Melibiase ABC_tran PF00005.27 EPE36206.1 - 2.1e-52 177.3 0.6 3.1e-29 102.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 EPE36206.1 - 2.7e-51 174.8 29.5 1.4e-32 113.4 10.4 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EPE36206.1 - 6.6e-08 32.3 1.7 0.0098 15.4 0.0 3.9 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EPE36206.1 - 8.3e-07 29.7 1.3 0.00068 20.2 0.1 2.7 3 0 0 3 3 2 2 AAA domain AAA_21 PF13304.6 EPE36206.1 - 8.5e-06 25.8 1.2 0.12 12.2 0.1 3.5 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EPE36206.1 - 8.7e-05 22.6 0.1 0.068 13.3 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPE36206.1 - 0.0001 22.2 0.1 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EPE36206.1 - 0.00013 21.6 0.4 0.25 11.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 EPE36206.1 - 0.00074 19.7 0.3 0.023 14.8 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain T2SSE PF00437.20 EPE36206.1 - 0.0024 17.0 0.1 0.032 13.3 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 EPE36206.1 - 0.0025 18.1 0.3 4.8 7.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EPE36206.1 - 0.0033 17.2 0.0 1.2 8.9 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 EPE36206.1 - 0.0041 17.5 0.4 4.4 7.7 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.6 EPE36206.1 - 0.0045 16.6 0.2 0.16 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.9 EPE36206.1 - 0.007 15.3 1.4 2.1 7.1 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 EPE36206.1 - 0.026 15.0 0.7 5.6 7.4 0.1 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EPE36206.1 - 0.026 13.8 0.1 4 6.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EPE36206.1 - 0.027 13.8 0.0 0.62 9.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.15 EPE36206.1 - 0.042 13.8 0.0 3 7.8 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EPE36206.1 - 0.045 14.3 0.3 6.1 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EPE36206.1 - 0.1 12.3 0.4 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain DEAD PF00270.29 EPE36206.1 - 0.13 12.0 0.0 10 5.8 0.0 3.1 3 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_7 PF12775.7 EPE36206.1 - 0.14 11.6 0.2 19 4.7 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Adeno_IVa2 PF02456.15 EPE36206.1 - 0.16 10.8 0.1 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein NACHT PF05729.12 EPE36206.1 - 0.16 11.9 1.8 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 EPE36206.1 - 0.17 11.4 1.2 1.2 8.7 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EPE36206.1 - 0.18 12.0 0.5 27 5.0 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EPE36206.1 - 0.22 11.9 0.5 44 4.5 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.6 EPE36206.1 - 0.27 10.9 1.2 9.1 5.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 EPE36206.1 - 0.3 11.1 1.1 4.8 7.2 0.0 2.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain SecY PF00344.20 EPE36207.1 - 1.4e-71 241.3 9.7 1.7e-71 241.0 9.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EPE36207.1 - 1.9e-17 62.8 0.3 6e-17 61.2 0.3 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p IPPT PF01715.17 EPE36208.1 - 8.6e-64 215.5 1.4 1.4e-63 214.8 1.4 1.3 1 0 0 1 1 1 1 IPP transferase AAA_33 PF13671.6 EPE36208.1 - 6.6e-06 26.3 1.6 5.8e-05 23.3 0.6 2.8 2 1 0 2 2 2 1 AAA domain zf-met PF12874.7 EPE36208.1 - 0.00016 21.9 0.2 0.00016 21.9 0.2 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type AAA_18 PF13238.6 EPE36208.1 - 0.0007 20.1 0.1 0.17 12.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain IPT PF01745.16 EPE36208.1 - 0.00091 18.7 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Isopentenyl transferase zf-C2H2_jaz PF12171.8 EPE36208.1 - 0.0011 19.2 0.7 0.0044 17.3 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding AAA_16 PF13191.6 EPE36208.1 - 0.0046 17.4 0.1 0.014 15.8 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 EPE36208.1 - 0.031 14.5 0.0 0.14 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EPE36208.1 - 0.044 14.3 0.0 0.21 12.1 0.0 2.2 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 EPE36208.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase zf-C2H2_2 PF12756.7 EPE36208.1 - 0.18 12.1 0.1 0.41 11.0 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) ORC2 PF04084.14 EPE36209.1 - 1.6e-125 418.5 0.0 2e-125 418.1 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Elong_Iki1 PF10483.9 EPE36209.1 - 0.57 9.6 3.0 9.4 5.6 0.3 2.3 2 0 0 2 2 2 0 Elongator subunit Iki1 Cut12 PF11500.8 EPE36210.1 - 3.4e-27 95.2 11.6 3.4e-27 95.2 11.6 5.3 3 2 2 5 5 5 1 Spindle pole body formation-associated protein RelA_SpoT PF04607.17 EPE36210.1 - 0.083 13.2 3.0 1.7 8.9 0.1 3.2 3 0 0 3 3 3 0 Region found in RelA / SpoT proteins KASH_CCD PF14662.6 EPE36210.1 - 5.1 6.9 26.7 0.11 12.3 18.0 2.5 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Cu-oxidase_3 PF07732.15 EPE36211.1 - 1.8e-40 137.7 1.5 6.7e-40 135.8 0.3 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EPE36211.1 - 5.7e-38 129.7 2.8 4.7e-33 113.8 0.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EPE36211.1 - 4.4e-27 95.1 0.0 1e-26 94.0 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Myc_target_1 PF15179.6 EPE36211.1 - 0.021 14.8 0.1 0.034 14.0 0.1 1.3 1 0 0 1 1 1 0 Myc target protein 1 Phosphoesterase PF04185.14 EPE36212.1 - 2.2e-34 119.2 0.5 1.4e-33 116.6 0.8 2.0 2 1 0 2 2 2 1 Phosphoesterase family DNA_pol_phi PF04931.13 EPE36213.1 - 8.8 4.3 8.9 11 4.0 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 EPE36214.1 - 3e-11 43.2 0.0 3.5e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE36214.1 - 4.2e-07 29.5 0.1 0.00056 19.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Ank_2 PF12796.7 EPE36215.1 - 5.2e-18 65.4 6.8 8e-09 36.0 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE36215.1 - 4.4e-08 33.2 5.9 0.00014 22.1 0.0 4.6 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPE36215.1 - 1.3e-07 32.0 7.9 0.0071 16.9 0.1 5.7 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE36215.1 - 5e-06 26.4 7.8 0.0033 17.8 0.0 6.7 7 1 0 7 7 7 1 Ankyrin repeat Ank PF00023.30 EPE36215.1 - 1.2e-05 25.5 10.8 0.0063 16.9 0.0 5.5 5 1 0 5 5 5 1 Ankyrin repeat DUF2791 PF10923.8 EPE36215.1 - 0.0041 16.0 0.0 0.0078 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) Phage_int_SAM_4 PF13495.6 EPE36215.1 - 0.092 13.2 0.0 0.43 11.1 0.0 2.2 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Zn_clus PF00172.18 EPE36216.1 - 3.1e-05 24.0 1.1 4.1e-05 23.6 1.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ge1_WD40 PF16529.5 EPE36218.1 - 0.00016 20.8 0.0 0.00033 19.7 0.0 1.5 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF624 PF04854.14 EPE36218.1 - 0.22 11.7 0.0 0.47 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF624 Gp23 PF07068.11 EPE36218.1 - 1.1 8.0 4.7 0.46 9.2 0.5 2.1 2 0 0 2 2 2 0 Major capsid protein Gp23 LicD PF04991.13 EPE36220.1 - 3.5e-21 76.4 4.8 5e-14 53.0 1.6 2.2 1 1 1 2 2 2 2 LicD family 4HBT PF03061.22 EPE36221.1 - 8.5e-09 35.7 0.1 1.3e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily K1 PF02960.14 EPE36221.1 - 0.053 13.6 0.1 0.45 10.6 0.0 1.9 2 0 0 2 2 2 0 K1 glycoprotein Scm3 PF10384.9 EPE36221.1 - 0.15 11.8 0.3 0.26 11.1 0.3 1.4 1 0 0 1 1 1 0 Centromere protein Scm3 Aldo_ket_red PF00248.21 EPE36222.1 - 5.5e-46 157.1 0.1 1.5e-44 152.4 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.14 EPE36223.1 - 5.4e-126 421.1 0.0 6.8e-126 420.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family baeRF_family2 PF18844.1 EPE36223.1 - 5.7 7.0 6.5 6.5 6.8 1.1 2.7 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 2 DivIVA PF05103.13 EPE36224.1 - 0.069 13.2 5.0 0.085 12.9 3.5 1.8 2 0 0 2 2 2 0 DivIVA protein Uteroglobin PF01099.17 EPE36224.1 - 0.16 12.3 1.1 0.4 11.0 0.1 2.1 2 1 1 3 3 3 0 Uteroglobin family GFA PF04828.14 EPE36225.1 - 3.9e-26 91.2 0.0 5e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2321 PF10083.9 EPE36225.1 - 0.16 11.5 1.5 2 8.0 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) ACBP PF00887.19 EPE36226.1 - 2.3e-22 79.0 0.0 4.7e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Atg14 PF10186.9 EPE36226.1 - 0.13 11.4 0.0 0.46 9.5 0.0 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 UvrB PF12344.8 EPE36226.1 - 0.17 11.8 3.4 0.14 12.1 0.6 2.2 2 0 0 2 2 2 0 Ultra-violet resistance protein B Ribonuclease_3 PF00636.26 EPE36227.1 - 1.3e-13 51.5 0.0 7.8e-13 49.0 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EPE36227.1 - 3.2e-09 37.0 0.0 7.6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 EPE36227.1 - 0.0065 17.2 0.4 0.0065 17.2 0.4 1.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif MRP-S33 PF08293.11 EPE36228.1 - 1.1e-30 105.6 0.3 1.6e-30 105.2 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 PUF PF00806.19 EPE36229.1 - 3.2e-36 121.0 1.3 8.5e-06 25.2 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RasGEF PF00617.19 EPE36229.1 - 0.016 15.4 0.2 0.29 11.3 0.0 2.8 2 1 0 3 3 3 0 RasGEF domain RraB PF06877.11 EPE36229.1 - 0.045 14.5 0.0 0.22 12.3 0.0 2.1 2 0 0 2 2 2 0 Regulator of ribonuclease activity B SBF2 PF12335.8 EPE36229.1 - 0.6 9.7 2.3 1.1 8.9 2.3 1.3 1 0 0 1 1 1 0 Myotubularin protein DUF5572 PF17733.1 EPE36230.1 - 5.8e-22 77.3 0.6 2.7e-21 75.1 0.4 2.3 1 1 1 2 2 2 1 Family of unknown function (DUF5572) TPPII_N PF12583.8 EPE36230.1 - 0.28 11.7 3.2 0.46 11.1 3.2 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal LSM14 PF12701.7 EPE36231.1 - 1e-29 102.4 0.0 1.6e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EPE36231.1 - 4.8e-19 69.2 2.8 4.8e-19 69.2 2.8 2.3 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.6 EPE36231.1 - 3.4e-05 23.9 0.0 6.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Sugar_tr PF00083.24 EPE36232.1 - 9.5e-92 308.2 29.8 1.2e-91 307.9 29.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE36232.1 - 6.4e-14 51.6 44.0 1.1e-11 44.3 15.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 EPE36233.1 - 1.3e-17 63.7 4.7 1.6e-08 33.8 0.0 2.9 2 1 0 2 2 2 2 Fungal specific transcription factor domain Toxin_16 PF07945.11 EPE36234.1 - 0.0038 17.1 0.3 0.0055 16.6 0.3 1.2 1 0 0 1 1 1 1 Janus-atracotoxin Zn_clus PF00172.18 EPE36235.1 - 3e-09 36.8 8.8 4.7e-09 36.2 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE36235.1 - 1.1e-07 31.0 0.1 1.8e-07 30.4 0.1 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF2781 PF10914.8 EPE36236.1 - 2.9e-14 53.7 6.9 3.3e-14 53.5 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) ORC6 PF05460.13 EPE36237.1 - 0.12 11.6 6.4 0.17 11.2 6.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DAAD PF18752.1 EPE36237.1 - 0.25 11.2 1.2 0.29 10.9 1.2 1.1 1 0 0 1 1 1 0 Dictyosteliid AID/APOBEC-like Deaminase Myb_DNA-bind_4 PF13837.6 EPE36238.1 - 0.00037 20.8 0.0 0.00064 20.0 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain HTH_12 PF08461.10 EPE36238.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain MIEAP PF16026.5 EPE36238.1 - 0.16 12.2 0.1 0.18 12.0 0.1 1.2 1 0 0 1 1 1 0 Mitochondria-eating protein TAP_C PF03943.13 EPE36239.1 - 0.16 11.6 0.1 0.4 10.3 0.1 1.7 1 0 0 1 1 1 0 TAP C-terminal domain Pox_Ag35 PF03286.14 EPE36239.1 - 0.26 11.1 7.6 0.35 10.7 7.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein ABC_transp_aux PF09822.9 EPE36242.1 - 0.07 12.6 0.1 0.087 12.3 0.1 1.1 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Cpn60_TCP1 PF00118.24 EPE36244.1 - 1.1e-85 288.2 10.5 2.7e-85 286.9 10.5 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.20 EPE36244.1 - 0.039 14.3 0.2 0.13 12.6 0.2 1.9 1 0 0 1 1 1 0 Transcriptional regulator EF1_GNE PF00736.19 EPE36245.1 - 8.9e-34 115.5 0.9 1.8e-33 114.6 0.9 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EPE36245.1 - 3.6e-14 52.9 8.2 3.6e-14 52.9 8.2 2.3 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 EPE36245.1 - 0.0005 20.2 0.7 0.0026 17.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EPE36245.1 - 0.001 19.3 1.3 0.0029 17.8 0.1 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.12 EPE36245.1 - 0.0051 16.6 1.1 0.0069 16.1 1.1 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3752 PF12572.8 EPE36245.1 - 0.023 15.2 0.7 0.034 14.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) MMgT PF10270.9 EPE36246.1 - 6.5e-38 129.1 0.0 7.6e-38 128.9 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter MutS_V PF00488.21 EPE36247.1 - 1.7e-48 165.2 0.0 3.1e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EPE36247.1 - 6.5e-18 65.6 0.0 1.4e-17 64.6 0.0 1.6 1 0 0 1 1 1 1 MutS domain III DUF908 PF06012.12 EPE36248.1 - 0.31 10.4 1.4 0.36 10.2 1.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) ABC2_membrane PF01061.24 EPE36249.1 - 1.7e-77 259.6 45.6 1.3e-44 152.1 17.0 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EPE36249.1 - 9.3e-36 123.4 0.2 9.2e-18 65.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EPE36249.1 - 1.2e-27 95.7 12.5 8.9e-25 86.4 0.1 3.2 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EPE36249.1 - 3.3e-15 56.5 4.2 3.3e-15 56.5 4.2 2.6 3 1 0 3 3 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 EPE36249.1 - 7.7e-06 25.9 0.0 0.024 14.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EPE36249.1 - 1.1e-05 25.9 0.3 0.0028 18.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EPE36249.1 - 1.2e-05 25.9 0.1 0.0048 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EPE36249.1 - 2.2e-05 23.8 9.2 2.2e-05 23.8 9.2 2.8 3 0 0 3 3 3 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EPE36249.1 - 3.9e-05 23.6 0.3 0.00045 20.2 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EPE36249.1 - 0.00024 20.8 0.6 0.44 10.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EPE36249.1 - 0.00038 20.5 1.1 0.071 13.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EPE36249.1 - 0.00041 20.5 0.2 0.067 13.4 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EPE36249.1 - 0.0021 18.3 0.1 0.0074 16.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain cobW PF02492.19 EPE36249.1 - 0.0026 17.4 0.1 0.012 15.2 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EPE36249.1 - 0.0045 16.6 0.3 0.35 10.4 0.1 3.2 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.6 EPE36249.1 - 0.0052 17.1 0.7 0.36 11.1 0.1 3.3 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 EPE36249.1 - 0.0057 16.1 1.5 0.16 11.4 0.0 3.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EPE36249.1 - 0.017 15.0 0.5 0.75 9.7 0.2 2.3 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 EPE36249.1 - 0.042 13.6 0.1 0.37 10.5 0.0 2.4 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EPE36249.1 - 0.044 13.1 0.6 7.7 5.8 0.2 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 EPE36249.1 - 0.057 13.1 1.0 3.3 7.4 0.3 3.0 3 0 0 3 3 3 0 AAA domain DUF1719 PF08224.11 EPE36249.1 - 0.06 12.4 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Dynamin_N PF00350.23 EPE36249.1 - 0.061 13.4 0.6 1.7 8.7 0.0 3.1 3 0 0 3 3 3 0 Dynamin family NB-ARC PF00931.22 EPE36249.1 - 0.097 11.8 0.5 1.8 7.7 0.1 2.5 3 0 0 3 3 3 0 NB-ARC domain Septin PF00735.18 EPE36249.1 - 0.11 11.8 0.1 0.5 9.6 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_17 PF13207.6 EPE36249.1 - 0.13 12.6 0.5 3.3 8.1 0.1 2.8 2 0 0 2 2 2 0 AAA domain PLAC8 PF04749.17 EPE36250.1 - 1.5e-18 67.6 19.1 1.8e-18 67.4 19.1 1.1 1 0 0 1 1 1 1 PLAC8 family DUF1752 PF08550.10 EPE36251.1 - 1.5e-10 40.7 4.3 3e-10 39.7 4.3 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) CBFB_NFYA PF02045.15 EPE36255.1 - 1.1e-27 96.3 4.6 1.1e-27 96.3 4.6 2.0 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Mif2_N PF15624.6 EPE36256.1 - 5.7e-37 127.4 0.3 5.7e-37 127.4 0.3 4.4 3 1 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 EPE36256.1 - 3.6e-33 113.6 0.6 7.3e-33 112.6 0.6 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 EPE36256.1 - 0.00013 21.6 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AT_hook PF02178.19 EPE36256.1 - 5.9 7.1 11.5 13 6.1 0.1 4.0 3 0 0 3 3 3 0 AT hook motif Met_10 PF02475.16 EPE36257.1 - 1e-69 234.3 0.0 1.5e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 EPE36257.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase 2OG-FeII_Oxy_2 PF13532.6 EPE36258.1 - 9.3e-28 97.7 0.0 3.8e-27 95.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FTO_NTD PF12933.7 EPE36258.1 - 0.17 11.1 0.0 0.67 9.1 0.0 1.8 1 1 0 2 2 2 0 FTO catalytic domain Prenyltransf PF01255.19 EPE36259.1 - 0.014 15.0 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase DUF3985 PF13153.6 EPE36259.1 - 3.6 7.7 7.1 0.43 10.6 2.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3985) Sec10 PF07393.11 EPE36260.1 - 8.7e-223 741.8 0.1 1e-222 741.5 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Baculo_PEP_C PF04513.12 EPE36260.1 - 2.3 8.2 8.0 1.1 9.3 0.5 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus COX17 PF05051.13 EPE36261.1 - 3.9e-20 71.9 7.3 4.7e-20 71.7 7.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) LRR_6 PF13516.6 EPE36262.1 - 1.5e-08 34.0 8.2 0.0021 18.0 0.0 6.4 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 EPE36262.1 - 7.4e-06 26.2 10.5 0.029 14.8 0.1 5.3 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EPE36262.1 - 0.0062 16.9 1.1 1.3e+02 3.8 0.1 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 EPE36262.1 - 0.0083 15.9 13.9 0.93 9.3 0.3 4.9 4 1 0 4 4 4 2 Leucine rich repeat DUF604 PF04646.12 EPE36262.1 - 0.24 10.8 0.4 20 4.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF604 adh_short PF00106.25 EPE36263.1 - 2e-41 141.6 0.2 2.7e-41 141.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE36263.1 - 2.3e-31 109.2 0.1 4.3e-31 108.3 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE36263.1 - 1.4e-14 54.5 0.1 4.9e-14 52.6 0.1 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EPE36263.1 - 0.00027 20.2 0.1 0.00036 19.8 0.1 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein AIRC PF00731.20 EPE36263.1 - 0.055 13.1 0.1 0.17 11.4 0.1 1.7 1 1 0 1 1 1 0 AIR carboxylase Epimerase PF01370.21 EPE36263.1 - 0.057 12.9 0.2 0.84 9.0 0.2 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Mito_carr PF00153.27 EPE36264.1 - 1.9e-53 178.4 3.7 4.3e-17 61.8 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF3341 PF11821.8 EPE36264.1 - 0.038 13.6 0.1 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Abp2 PF09441.10 EPE36265.1 - 5.4e-85 283.7 0.0 7.6e-85 283.2 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 DUF4597 PF15366.6 EPE36265.1 - 3.7 7.4 10.6 8.2 6.3 3.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4597) Sugar_tr PF00083.24 EPE36266.1 - 8.1e-96 321.6 22.5 9.6e-96 321.4 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE36266.1 - 5.3e-15 55.2 35.7 6.8e-15 54.8 30.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EPE36267.1 - 8.9e-75 252.2 0.0 1.5e-59 202.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 WW PF00397.26 EPE36268.1 - 6.3e-10 39.0 0.3 1.1e-09 38.2 0.3 1.4 1 0 0 1 1 1 1 WW domain Pga1 PF10333.9 EPE36269.1 - 6.6e-08 32.6 0.2 1.2e-06 28.5 0.2 2.3 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Tubulin PF00091.25 EPE36270.1 - 1.1e-66 224.9 0.0 1.6e-66 224.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EPE36270.1 - 8.3e-50 168.2 0.1 1.4e-49 167.5 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EPE36270.1 - 0.0057 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain MFS_1 PF07690.16 EPE36271.1 - 1.8e-31 109.4 31.9 1.8e-31 109.4 31.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2681 PF10883.8 EPE36271.1 - 0.044 14.2 0.6 0.52 10.7 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) SH3_1 PF00018.28 EPE36272.1 - 5.2e-37 125.2 7.5 8.3e-14 50.9 0.1 4.1 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 EPE36272.1 - 4.3e-36 122.5 7.7 4.9e-11 42.3 0.2 3.4 3 0 0 3 3 3 3 Variant SH3 domain SHD1 PF03983.12 EPE36272.1 - 3.6e-34 116.4 0.1 6.1e-34 115.7 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 EPE36272.1 - 1e-23 82.8 0.7 3.3e-09 36.3 0.0 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.11 EPE36272.1 - 5.4e-06 26.6 5.0 0.0017 18.6 1.1 3.4 3 0 0 3 3 3 1 Bacterial SH3 domain SAM_4 PF18017.1 EPE36272.1 - 0.00045 20.1 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_10 PF17902.1 EPE36272.1 - 0.00054 20.0 0.0 0.15 12.2 0.0 3.3 3 0 0 3 3 3 1 SH3 domain SIN1_PH PF16979.5 EPE36272.1 - 0.15 12.3 0.6 17 5.7 0.3 3.3 2 1 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Cu-oxidase_2 PF07731.14 EPE36274.1 - 1.3e-42 144.8 5.9 6.7e-40 136.0 0.6 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EPE36274.1 - 1.7e-42 144.2 3.0 1e-39 135.2 1.6 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EPE36274.1 - 1.8e-35 122.4 4.6 2.2e-32 112.4 0.7 2.8 3 0 0 3 3 3 2 Multicopper oxidase PP2C PF00481.21 EPE36274.1 - 6.6e-34 117.7 0.0 1.9e-28 99.8 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C Cupredoxin_1 PF13473.6 EPE36274.1 - 0.013 15.5 0.0 27 4.9 0.0 3.6 3 1 0 3 3 3 0 Cupredoxin-like domain PP2C_2 PF13672.6 EPE36274.1 - 0.031 13.9 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C PPC PF04151.15 EPE36274.1 - 0.078 14.1 0.1 8.3 7.6 0.1 2.9 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain FTR1 PF03239.14 EPE36275.1 - 1.8e-80 270.4 9.6 2.1e-80 270.2 9.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4231 PF14015.6 EPE36275.1 - 2.1 8.8 6.4 0.19 12.2 0.8 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF2070 PF09843.9 EPE36275.1 - 5.5 5.2 9.1 8.9 4.5 9.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Dor1 PF04124.12 EPE36276.1 - 4.1e-53 180.2 3.4 2.3e-42 144.9 7.1 2.3 2 0 0 2 2 2 2 Dor1-like family Sec5 PF15469.6 EPE36276.1 - 0.0056 16.5 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 EPE36276.1 - 0.042 13.9 0.5 0.18 11.9 0.3 2.2 2 0 0 2 2 2 0 Vps51/Vps67 Peptidase_U40 PF10464.9 EPE36278.1 - 0.044 13.4 0.1 3.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Peptidase U40 TRAM_LAG1_CLN8 PF03798.16 EPE36279.1 - 1.2e-54 185.1 8.9 1.2e-54 185.1 8.9 1.5 2 0 0 2 2 2 1 TLC domain A_deaminase PF00962.22 EPE36280.1 - 1.5e-123 412.4 0.1 2e-123 411.9 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.11 EPE36281.1 - 2e-94 316.2 4.1 3e-94 315.6 4.1 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EPE36281.1 - 0.00017 21.8 24.0 0.044 14.0 7.4 4.0 2 2 1 3 3 3 3 EamA-like transporter family TMEM234 PF10639.9 EPE36281.1 - 0.028 14.4 1.3 0.2 11.7 0.3 2.4 2 0 0 2 2 2 0 Putative transmembrane family 234 TssN PF17555.2 EPE36281.1 - 0.12 11.7 4.6 0.3 10.4 2.0 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN WD40 PF00400.32 EPE36282.1 - 4.5e-13 49.5 3.2 0.12 13.3 0.2 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE36282.1 - 0.0095 16.2 0.1 2.7 8.3 0.0 3.7 4 2 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain CENP-Q PF13094.6 EPE36283.1 - 0.041 14.1 0.1 0.087 13.0 0.1 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit PBP PF01161.20 EPE36285.1 - 6.9e-16 58.8 0.0 1e-15 58.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Dynamin_M PF01031.20 EPE36286.1 - 8.9e-111 369.7 0.0 2e-110 368.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EPE36286.1 - 8.9e-57 191.8 0.1 2.5e-56 190.4 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 EPE36286.1 - 2.3e-31 107.8 1.8 6.7e-31 106.3 1.8 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EPE36286.1 - 0.00016 21.7 0.4 0.0012 18.9 0.4 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase LtrA PF06772.11 EPE36287.1 - 3.2e-50 171.3 26.8 4.3e-50 170.9 26.8 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) SBP_bac_11 PF13531.6 EPE36287.1 - 0.19 11.4 0.0 0.32 10.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Metal_resist PF13801.6 EPE36287.1 - 0.32 11.2 7.8 0.23 11.7 2.1 2.3 1 1 1 2 2 2 0 Heavy-metal resistance SOGA PF11365.8 EPE36290.1 - 0.034 15.3 1.6 0.034 15.3 1.6 3.5 2 2 1 3 3 3 0 Protein SOGA DUF948 PF06103.11 EPE36290.1 - 0.12 12.7 3.4 0.88 9.9 0.1 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) PilJ PF13675.6 EPE36290.1 - 2.5 8.1 5.8 11 6.1 0.1 3.3 4 0 0 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term ATG16 PF08614.11 EPE36290.1 - 3.1 8.0 29.6 0.057 13.6 8.8 3.4 2 1 0 3 3 3 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 EPE36290.1 - 5.4 7.5 8.5 3.2 8.2 0.4 3.8 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 EPE36290.1 - 8.9 6.7 26.9 1.1 9.7 8.1 3.2 1 1 2 3 3 3 0 Fez1 Mak10 PF04112.13 EPE36291.1 - 5.5e-64 214.7 0.1 1.2e-63 213.6 0.1 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.13 EPE36292.1 - 2.4e-23 81.8 1.5 3.9e-23 81.2 1.5 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16_C PF05193.21 EPE36293.1 - 1.1e-15 58.2 0.0 1.7e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EPE36293.1 - 4.5e-12 46.2 0.0 7.8e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) RNA_pol_Rpc82 PF05645.13 EPE36294.1 - 4.5e-52 177.4 0.1 3.5e-48 164.6 0.0 2.6 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EPE36294.1 - 4.6e-16 58.7 1.2 1.4e-14 53.9 0.1 3.7 5 0 0 5 5 5 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EPE36294.1 - 9.2e-10 38.3 0.7 0.00036 20.4 1.1 3.5 3 0 0 3 3 3 2 TFIIE alpha subunit Cdc6_C PF09079.11 EPE36294.1 - 0.11 12.5 0.0 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain HTH_20 PF12840.7 EPE36294.1 - 5.6 7.1 8.3 7.6 6.7 0.1 4.6 6 0 0 6 6 6 0 Helix-turn-helix domain Mito_carr PF00153.27 EPE36295.1 - 3.2e-29 100.7 1.2 3.1e-15 55.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein NCE101 PF11654.8 EPE36296.1 - 3.4e-09 36.3 0.0 5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Non-classical export protein 1 Atg8 PF02991.16 EPE36298.1 - 4.7e-51 171.3 0.2 5.6e-51 171.1 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EPE36298.1 - 2.5e-06 27.8 0.0 3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.18 EPE36299.1 - 1.5e-146 486.8 0.2 1.8e-146 486.5 0.2 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SWIM PF04434.17 EPE36300.1 - 0.003 17.2 0.6 0.14 11.9 0.1 2.3 2 0 0 2 2 2 2 SWIM zinc finger MitMem_reg PF13012.6 EPE36301.1 - 2.2e-37 127.9 0.1 3.8e-37 127.1 0.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EPE36301.1 - 2.1e-30 105.1 0.0 6.3e-30 103.6 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 EPE36301.1 - 0.056 13.1 7.0 0.084 12.6 7.0 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain Connexin PF00029.19 EPE36301.1 - 0.87 9.3 3.1 1.3 8.7 3.1 1.2 1 0 0 1 1 1 0 Connexin O-antigen_lig PF13425.6 EPE36301.1 - 2.6 6.8 3.3 3.5 6.3 3.3 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ADK PF00406.22 EPE36302.1 - 1e-57 194.5 0.0 1.4e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EPE36302.1 - 1.5e-21 77.2 0.3 3.5e-21 76.0 0.3 1.7 1 1 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EPE36302.1 - 2.4e-17 62.6 0.0 5.4e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EPE36302.1 - 5.9e-06 26.9 0.0 1.6e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EPE36302.1 - 0.00028 21.1 0.0 0.00042 20.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain FAP PF07174.11 EPE36303.1 - 5.9 6.3 18.9 8.7 5.7 18.9 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF4551 PF15087.6 EPE36303.1 - 7.4 5.3 9.0 10 4.8 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ribosomal_60s PF00428.19 EPE36304.1 - 6.3e-28 97.2 9.2 7.2e-28 97.0 9.2 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 EPE36304.1 - 0.0054 17.0 0.0 0.0054 17.0 0.0 1.4 2 0 0 2 2 2 1 EF-hand domain UBA_6 PF18039.1 EPE36304.1 - 0.03 14.2 0.2 0.068 13.1 0.0 1.6 2 0 0 2 2 2 0 UBA-like domain Cytomega_UL84 PF06284.11 EPE36304.1 - 0.26 9.7 0.9 0.28 9.6 0.9 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF3824 PF12868.7 EPE36304.1 - 1.8 9.2 4.7 2.6 8.7 4.7 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF2967 PF11179.8 EPE36304.1 - 7.7 4.5 7.0 1.9 6.5 4.3 1.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) CTD_bind PF04818.13 EPE36305.1 - 7.4e-05 23.5 0.0 0.00052 20.8 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase II-binding domain. VHS PF00790.19 EPE36305.1 - 0.00062 19.6 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 VHS domain CFIA_Pcf11 PF11526.8 EPE36305.1 - 0.00089 19.7 0.0 0.0025 18.2 0.0 1.9 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 zf-C2H2_4 PF13894.6 EPE36305.1 - 0.0096 16.7 2.0 3.9 8.6 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-CCHC_4 PF14392.6 EPE36305.1 - 0.095 12.4 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle Zn-C2H2_12 PF18112.1 EPE36305.1 - 0.68 10.4 3.3 2.2 8.8 0.2 2.6 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf_UBZ PF18439.1 EPE36305.1 - 1.2 8.8 8.8 0.5 10.0 3.5 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 EPE36305.1 - 4.3 8.0 6.1 35 5.1 0.1 3.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type Inhibitor_I9 PF05922.16 EPE36306.1 - 0.063 14.0 0.0 0.093 13.4 0.0 1.4 1 1 0 1 1 1 0 Peptidase inhibitor I9 Val_tRNA-synt_C PF10458.9 EPE36306.1 - 0.17 12.2 0.0 0.67 10.3 0.0 1.8 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm HOOK PF05622.12 EPE36307.1 - 0.0035 15.6 59.4 0.0034 15.6 51.8 2.8 2 1 1 3 3 3 1 HOOK protein Tropomyosin_1 PF12718.7 EPE36307.1 - 0.0078 16.4 19.8 0.0078 16.4 19.8 5.2 2 2 3 5 5 5 3 Tropomyosin like DASH_Dad4 PF08650.10 EPE36307.1 - 0.018 15.0 3.6 0.083 12.9 0.8 3.4 2 1 1 3 3 3 0 DASH complex subunit Dad4 DUF4754 PF15946.5 EPE36307.1 - 0.68 10.2 3.1 0.48 10.7 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4754) DGF-1_C PF11040.8 EPE36307.1 - 3.8 7.6 5.3 1.7 8.7 0.2 3.2 3 1 1 4 4 4 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus 3HCDH_N PF02737.18 EPE36307.1 - 6.2 6.7 13.3 0.072 13.0 4.2 2.5 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 EPE36308.1 - 1.2e-09 37.5 2.0 1.6e-09 37.1 2.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE36308.1 - 0.0058 16.7 1.6 0.0095 16.0 1.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cys_Met_Meta_PP PF01053.20 EPE36309.1 - 5e-143 476.2 0.2 5.7e-143 476.1 0.2 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EPE36309.1 - 9.1e-08 31.7 0.1 1.4e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPE36309.1 - 6.5e-07 28.6 0.6 1.2e-06 27.7 0.3 1.5 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EPE36309.1 - 1e-06 28.3 0.5 2.1e-06 27.3 0.2 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EPE36309.1 - 0.001 18.4 0.1 0.0025 17.2 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 EPE36309.1 - 0.03 13.2 0.1 0.046 12.6 0.1 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein RNA_pol_Rbc25 PF08292.12 EPE36310.1 - 3.1e-35 121.2 0.1 4.6e-35 120.7 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EPE36310.1 - 1.4e-14 54.2 0.0 3.8e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EPE36310.1 - 0.00036 20.8 0.0 0.00062 20.0 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain SdrG_C_C PF10425.9 EPE36310.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 C-terminus of bacterial fibrinogen-binding adhesin NUFIP1 PF10453.9 EPE36311.1 - 0.0008 19.2 0.2 0.0008 19.2 0.2 2.1 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 EPE36311.1 - 0.032 14.3 6.7 0.067 13.3 6.7 1.6 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 EPE36311.1 - 0.097 12.6 5.0 0.22 11.5 5.0 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CHD5 PF04420.14 EPE36311.1 - 3.8 7.3 5.9 6.1 6.7 5.9 1.2 1 0 0 1 1 1 0 CHD5-like protein Dynamin_N PF00350.23 EPE36312.1 - 5e-16 59.2 4.6 1.9e-15 57.3 0.0 4.0 3 1 1 4 4 4 1 Dynamin family MMR_HSR1 PF01926.23 EPE36312.1 - 1.2e-06 28.5 0.0 1.5e-05 25.0 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 EPE36312.1 - 4.2e-05 22.8 0.0 0.00081 18.5 0.0 2.8 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 EPE36312.1 - 0.00046 20.1 0.6 0.0024 17.8 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 EPE36312.1 - 0.00078 18.9 0.0 0.0032 16.9 0.0 2.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EPE36312.1 - 0.0025 16.9 0.0 0.0073 15.4 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 EPE36312.1 - 0.0042 17.6 0.0 0.0042 17.6 0.0 3.8 4 0 0 4 4 4 1 ABC transporter KAP_NTPase PF07693.14 EPE36312.1 - 0.039 13.2 2.3 0.23 10.6 1.9 2.6 2 1 0 2 2 2 0 KAP family P-loop domain Roc PF08477.13 EPE36312.1 - 0.046 13.9 0.2 1.9 8.7 0.0 3.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 EPE36312.1 - 0.049 13.4 0.1 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 EPE36312.1 - 0.053 14.0 0.0 0.053 14.0 0.0 5.2 4 1 2 6 6 3 0 AAA domain AAA_29 PF13555.6 EPE36312.1 - 0.062 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 EPE36312.1 - 0.11 12.5 0.2 0.11 12.5 0.2 3.8 3 1 0 3 3 3 0 Helicase HerA, central domain AAA_16 PF13191.6 EPE36312.1 - 0.57 10.6 3.5 1.1 9.6 0.0 3.1 3 1 1 4 4 4 0 AAA ATPase domain RRM_1 PF00076.22 EPE36314.1 - 3.3e-13 49.3 0.5 1.6e-08 34.3 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIF_alpha PF05793.12 EPE36314.1 - 0.97 7.9 31.7 2.7 6.5 31.7 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3435 PF11917.8 EPE36314.1 - 2.3 7.1 8.9 3.4 6.5 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) CHORD PF04968.12 EPE36315.1 - 3.1e-34 117.5 15.3 1.8e-24 86.2 6.7 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 EPE36315.1 - 9.4e-11 42.6 0.1 1.7e-10 41.7 0.1 1.5 1 0 0 1 1 1 1 CS domain DUF2721 PF11026.8 EPE36316.1 - 0.064 13.1 0.4 0.1 12.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) WH2 PF02205.20 EPE36318.1 - 2.5e-10 39.8 0.7 8.5e-10 38.2 0.7 2.0 1 0 0 1 1 1 1 WH2 motif SURF4 PF02077.15 EPE36319.1 - 3.6e-97 325.1 7.2 4.1e-97 324.9 7.2 1.0 1 0 0 1 1 1 1 SURF4 family DUF1129 PF06570.11 EPE36319.1 - 0.47 9.9 4.7 0.17 11.3 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Sgf11 PF08209.11 EPE36320.1 - 0.0037 16.8 0.1 0.007 15.9 0.1 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) DUF3336 PF11815.8 EPE36321.1 - 2.5e-33 114.7 0.0 3.7e-32 110.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EPE36321.1 - 5.2e-14 52.9 0.4 1.1e-13 51.9 0.4 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3237 PF11578.8 EPE36322.1 - 1.8e-32 112.2 0.0 2e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF4040 PF13244.6 EPE36322.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4040) Mob1_phocein PF03637.17 EPE36323.1 - 2.3e-42 144.9 0.6 1.7e-41 142.1 0.6 2.0 1 1 0 1 1 1 1 Mob1/phocein family Leo1 PF04004.13 EPE36324.1 - 1.5e-35 122.5 0.0 1.5e-35 122.5 0.0 1.8 2 0 0 2 2 2 1 Leo1-like protein Choline_kinase PF01633.20 EPE36325.1 - 8.5e-53 179.1 0.0 1.4e-51 175.1 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EPE36325.1 - 5.6e-11 42.8 0.0 1.5e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EPE36325.1 - 0.0015 17.9 0.0 0.013 14.9 0.0 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase gp32 PF08804.10 EPE36325.1 - 0.066 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 gp32 DNA binding protein like DUF1679 PF07914.11 EPE36325.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Voltage_CLC PF00654.20 EPE36326.1 - 4.2e-87 292.7 15.7 4.2e-87 292.7 15.7 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EPE36326.1 - 0.029 14.8 0.0 0.079 13.4 0.0 1.8 1 0 0 1 1 1 0 CBS domain BofA PF07441.11 EPE36326.1 - 0.11 12.7 3.8 0.14 12.4 1.5 2.3 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA PsbX PF06596.11 EPE36326.1 - 0.93 9.6 0.0 0.93 9.6 0.0 3.6 4 0 0 4 4 4 0 Photosystem II reaction centre X protein (PsbX) DUF3425 PF11905.8 EPE36327.1 - 3.4e-07 30.3 0.1 1.7e-06 28.0 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EPE36327.1 - 0.00019 21.5 19.3 0.00056 20.0 19.6 1.7 1 1 1 2 2 2 1 bZIP transcription factor MFAP1 PF06991.11 EPE36327.1 - 0.015 15.1 7.3 0.022 14.6 7.3 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing EMC3_TMCO1 PF01956.16 EPE36327.1 - 0.18 11.5 0.3 0.27 10.9 0.3 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like bZIP_Maf PF03131.17 EPE36327.1 - 0.2 12.2 12.8 0.4 11.2 12.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 EPE36327.1 - 8.4 6.6 24.8 1.6e+03 -0.8 24.8 2.4 1 1 0 1 1 1 0 Basic region leucine zipper Zn_clus PF00172.18 EPE36328.1 - 2.5e-05 24.3 9.8 4.5e-05 23.5 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BOP1NT PF08145.12 EPE36329.1 - 5.2e-105 351.0 6.6 7.9e-105 350.5 6.6 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EPE36329.1 - 1.3e-19 70.2 0.4 8.3e-10 39.1 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE36329.1 - 3.7e-05 23.9 0.0 0.0019 18.5 0.0 3.4 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain MFMR_assoc PF16596.5 EPE36329.1 - 2.8 8.4 5.4 5 7.6 5.4 1.3 1 0 0 1 1 1 0 Disordered region downstream of MFMR RNase_HII PF01351.18 EPE36330.1 - 2.5e-46 158.0 0.0 5.7e-46 156.9 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease HII Fructosamin_kin PF03881.14 EPE36331.1 - 1e-61 208.7 0.0 1.2e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EPE36331.1 - 0.00015 21.8 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_4 PF12763.7 EPE36332.1 - 4.1e-33 113.5 0.0 5.3e-14 52.0 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 EPE36332.1 - 4e-06 26.6 0.6 8.3e-06 25.6 0.6 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.6 EPE36332.1 - 4.9e-05 23.7 0.0 0.009 16.4 0.0 3.5 4 0 0 4 4 4 1 EF-hand domain pair TMF_TATA_bd PF12325.8 EPE36332.1 - 0.0083 16.3 4.0 0.0083 16.3 4.0 3.2 2 1 0 3 3 3 1 TATA element modulatory factor 1 TATA binding EF-hand_6 PF13405.6 EPE36332.1 - 0.0083 16.0 0.0 25 5.1 0.1 4.3 5 0 0 5 5 5 0 EF-hand domain Spc7 PF08317.11 EPE36332.1 - 0.023 13.6 35.3 0.011 14.6 23.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Macoilin PF09726.9 EPE36332.1 - 0.043 12.4 22.3 0.068 11.7 22.3 1.2 1 0 0 1 1 1 0 Macoilin family LPP PF04728.13 EPE36332.1 - 4.3 7.8 9.1 6.6 7.2 1.0 3.5 2 1 2 4 4 4 0 Lipoprotein leucine-zipper FUSC PF04632.12 EPE36332.1 - 4.6 5.7 11.1 6.8 5.1 11.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PRKG1_interact PF15898.5 EPE36332.1 - 6.7 7.7 31.8 1.8 9.5 12.2 3.3 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain CorA PF01544.18 EPE36333.1 - 0.00016 21.1 0.2 0.0027 17.1 0.2 2.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Acetyltransf_10 PF13673.7 EPE36334.1 - 5.4e-10 39.3 0.0 6e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE36334.1 - 2.4e-09 37.4 0.0 3.3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPE36334.1 - 7.2e-09 35.9 0.0 1.5e-08 35.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE36334.1 - 4.5e-05 23.3 0.0 8.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EPE36334.1 - 0.0025 17.9 0.1 0.017 15.2 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EPE36334.1 - 0.021 14.8 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_3 PF13302.7 EPE36334.1 - 0.055 14.1 0.0 0.074 13.7 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EPE36334.1 - 0.077 12.5 0.0 0.077 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase GNAT_acetyltran PF12746.7 EPE36334.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.5 1 1 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_CG PF14542.6 EPE36334.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase CFEM PF05730.11 EPE36335.1 - 2.2e-06 27.6 8.1 4.5e-06 26.6 8.1 1.5 1 0 0 1 1 1 1 CFEM domain TetR_C_16 PF17920.1 EPE36335.1 - 0.074 13.3 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF2052 PF09747.9 EPE36336.1 - 0.0022 18.1 22.0 0.006 16.7 10.9 2.5 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) PTPRCAP PF15713.5 EPE36336.1 - 0.0027 18.0 4.0 0.0027 18.0 4.0 3.9 4 0 0 4 4 4 1 Protein tyrosine phosphatase receptor type C-associated YL1 PF05764.13 EPE36336.1 - 0.097 12.8 44.7 0.016 15.3 4.5 3.2 3 0 0 3 3 3 0 YL1 nuclear protein CPSF100_C PF13299.6 EPE36336.1 - 1.1 9.5 13.1 4.5 7.4 3.9 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EPL1 PF10513.9 EPE36336.1 - 1.5 9.2 22.6 0.025 15.0 1.8 2.7 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF913 PF06025.12 EPE36336.1 - 2.9 6.8 9.8 0.94 8.4 2.9 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) CCDC106 PF15794.5 EPE36336.1 - 3.9 7.1 29.5 0.85 9.3 4.6 3.1 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 EPE36336.1 - 4.4 5.5 35.9 0.013 13.9 1.0 2.4 3 0 0 3 3 3 0 CDC45-like protein SR-25 PF10500.9 EPE36336.1 - 5.3 6.6 27.3 0.64 9.6 2.6 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.12 EPE36336.1 - 8.3 6.1 22.3 1.3 8.8 8.8 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 WD40 PF00400.32 EPE36337.1 - 6.6e-37 124.9 15.0 3.4e-07 30.8 0.8 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.11 EPE36337.1 - 1.9e-14 52.9 4.4 3.6e-14 52.0 4.4 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EPE36337.1 - 6.3e-13 48.8 0.1 0.27 11.6 0.0 5.6 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPE36337.1 - 0.096 12.6 0.1 27 4.6 0.0 3.3 2 1 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A COBRA PF04833.15 EPE36340.1 - 0.18 11.7 0.0 23 4.8 0.0 2.3 2 0 0 2 2 2 0 COBRA-like protein Sugar_tr PF00083.24 EPE36341.1 - 3.3e-26 92.2 22.1 2.2e-15 56.5 7.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter CorA PF01544.18 EPE36342.1 - 2.4e-12 46.8 2.0 5.5e-12 45.6 2.0 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF676 PF05057.14 EPE36342.1 - 0.0024 17.4 0.2 0.0057 16.2 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EPE36342.1 - 0.0026 18.4 0.2 0.098 13.2 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE36342.1 - 0.012 14.9 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 EPE36342.1 - 0.088 12.4 0.0 0.29 10.7 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase PGAP1 PF07819.13 EPE36342.1 - 0.097 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF4168 PF13767.6 EPE36342.1 - 0.98 10.6 4.8 2 9.7 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) tRNA_anti-codon PF01336.25 EPE36343.1 - 0.12 12.4 0.1 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Pkinase PF00069.25 EPE36344.1 - 2.9e-61 207.2 0.0 1.8e-60 204.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE36344.1 - 8.2e-30 103.9 0.0 1.6e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EPE36344.1 - 3.6e-08 33.6 0.2 3e-06 27.5 0.1 2.6 2 0 0 2 2 2 1 FHA domain APH PF01636.23 EPE36344.1 - 0.0041 17.1 0.0 2 8.3 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family COesterase PF00135.28 EPE36345.1 - 1.6e-89 301.1 0.0 2.4e-89 300.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EPE36345.1 - 0.00066 19.2 0.1 0.0011 18.5 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EPE36345.1 - 0.00098 19.0 0.1 0.0043 16.9 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Myb_DNA-binding PF00249.31 EPE36345.1 - 0.17 12.1 0.1 0.44 10.8 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain GPI-anchored PF10342.9 EPE36346.1 - 3.5e-13 50.1 1.1 8.1e-13 49.0 0.0 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Sigma_reg_N PF13800.6 EPE36346.1 - 0.24 11.7 2.2 0.65 10.3 0.3 2.5 1 1 2 3 3 3 0 Sigma factor regulator N-terminal GPI-anchored PF10342.9 EPE36348.1 - 1.1e-15 58.1 2.4 1.1e-15 58.1 2.4 3.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MG2 PF01835.19 EPE36348.1 - 0.25 11.8 1.8 0.27 11.7 0.1 1.9 2 0 0 2 2 2 0 MG2 domain SOG2 PF10428.9 EPE36348.1 - 4.3 6.4 24.4 5 6.2 24.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Miga PF10265.9 EPE36348.1 - 4.7 6.1 12.1 5.6 5.8 12.1 1.3 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 EPE36348.1 - 8.8 4.7 12.8 11 4.5 12.8 1.2 1 0 0 1 1 1 0 Macoilin family Ribul_P_3_epim PF00834.19 EPE36349.1 - 1.7e-62 210.4 0.0 1.4e-61 207.4 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 EPE36349.1 - 0.051 12.9 0.1 0.07 12.4 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 EPE36349.1 - 0.089 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family p450 PF00067.22 EPE36350.1 - 4.7e-94 315.7 0.0 5.6e-94 315.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pex14_N PF04695.13 EPE36351.1 - 6.3 7.4 8.0 2 9.1 0.3 2.6 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ofd1_CTDD PF10637.9 EPE36352.1 - 2.3e-89 299.1 13.5 1.6e-85 286.5 13.0 2.5 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EPE36352.1 - 1.1e-25 90.1 0.0 8.6e-25 87.2 0.0 2.5 3 1 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EPE36352.1 - 6.8e-13 49.3 0.0 1.6e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CDC45 PF02724.14 EPE36352.1 - 0.67 8.2 14.3 1.4 7.1 14.3 1.5 1 0 0 1 1 1 0 CDC45-like protein CSRNP_N PF16019.5 EPE36352.1 - 2.3 8.1 5.3 0.33 10.8 0.6 1.9 1 1 1 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Aminotran_5 PF00266.19 EPE36353.1 - 1.4e-55 188.8 0.0 1.6e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EPE36353.1 - 0.00016 20.3 0.0 0.00033 19.3 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EPE36353.1 - 0.0082 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II p450 PF00067.22 EPE36354.1 - 3.3e-43 148.1 0.0 4.4e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IRS PF02174.17 EPE36354.1 - 0.086 12.7 0.4 5.9 6.8 0.0 2.5 2 1 0 2 2 2 0 PTB domain (IRS-1 type) DUF5313 PF17240.2 EPE36358.1 - 0.012 16.0 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5313) MAGI_u1 PF16663.5 EPE36364.1 - 1.4 9.0 7.8 29 4.8 0.2 3.9 2 1 2 4 4 4 0 Unstructured region on MAGI WD40 PF00400.32 EPE36365.1 - 1.8e-07 31.7 7.0 0.92 10.5 0.2 6.3 7 1 0 7 7 7 3 WD domain, G-beta repeat ATP-synt_E PF05680.12 EPE36366.1 - 9.2e-22 77.2 0.1 1e-21 77.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain STT3 PF02516.14 EPE36367.1 - 3.8e-143 478.0 30.9 4.1e-138 461.3 29.0 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Glucan_synthase PF02364.15 EPE36367.1 - 0.035 12.3 0.0 0.035 12.3 0.0 1.6 2 0 0 2 2 2 0 1,3-beta-glucan synthase component Dpy19 PF10034.9 EPE36367.1 - 0.34 9.1 0.0 0.34 9.1 0.0 2.1 1 1 1 2 2 2 0 Q-cell neuroblast polarisation TPR_2 PF07719.17 EPE36369.1 - 1.9e-20 71.2 2.4 2.7e-05 23.9 0.1 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EPE36369.1 - 1.4e-19 69.0 2.6 4.1e-06 26.4 0.0 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EPE36369.1 - 4.2e-15 55.2 2.1 2.8e-06 26.9 0.0 5.1 4 1 1 5 5 5 3 TPR repeat TPR_8 PF13181.6 EPE36369.1 - 2.3e-14 52.3 1.3 5e-05 23.2 0.0 5.3 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EPE36369.1 - 1.2e-12 46.9 3.3 0.014 15.4 0.1 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EPE36369.1 - 1.3e-12 47.4 4.6 0.0019 18.8 0.1 5.8 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EPE36369.1 - 1.4e-12 48.1 4.4 0.00094 19.8 0.1 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EPE36369.1 - 7.7e-12 45.6 5.5 0.00053 20.4 1.5 4.7 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EPE36369.1 - 1.1e-11 44.9 7.3 1e-05 25.7 0.9 4.1 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EPE36369.1 - 2.2e-10 40.2 1.9 0.88 10.1 0.0 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_20 PF14561.6 EPE36369.1 - 5.3e-10 39.5 0.6 0.0066 16.8 0.0 4.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 EPE36369.1 - 3.9e-09 36.5 0.5 0.024 14.8 0.1 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE36369.1 - 3.2e-06 27.3 2.3 0.0016 18.6 0.5 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EPE36369.1 - 8e-06 26.2 3.0 5.5 7.8 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 EPE36369.1 - 0.00048 20.1 0.1 35 4.6 0.0 4.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 EPE36369.1 - 0.025 14.5 7.4 0.05 13.5 0.5 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 EPE36369.1 - 0.027 14.5 0.0 7.6 6.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 EPE36369.1 - 0.064 12.5 3.1 4.2 6.5 0.2 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF1992 PF09350.10 EPE36369.1 - 0.13 12.4 2.2 0.9 9.7 0.0 3.0 3 1 0 3 3 2 0 Domain of unknown function (DUF1992) BTAD PF03704.17 EPE36369.1 - 0.84 10.1 6.8 18 5.7 0.2 3.9 3 1 1 4 4 3 0 Bacterial transcriptional activator domain RRM_1 PF00076.22 EPE36370.1 - 4.9e-36 122.4 1.3 2e-18 66.0 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 EPE36370.1 - 0.056 13.1 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_7 PF16367.5 EPE36370.1 - 0.17 12.0 0.2 2.8 8.1 0.1 2.6 2 1 0 2 2 2 0 RNA recognition motif HLH PF00010.26 EPE36371.1 - 9.3e-13 47.9 0.4 2.4e-12 46.6 0.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 EPE36371.1 - 0.046 14.2 0.2 0.14 12.6 0.2 1.7 1 0 0 1 1 1 0 Cell division protein ZapB YabA PF06156.13 EPE36371.1 - 0.074 13.7 1.4 0.12 13.0 0.1 2.0 2 1 0 2 2 2 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 EPE36371.1 - 0.083 13.1 0.2 0.083 13.1 0.2 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4776 PF16003.5 EPE36371.1 - 0.14 11.1 0.4 0.21 10.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Phage_GPO PF05929.11 EPE36371.1 - 0.21 11.2 2.0 0.16 11.6 0.2 1.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase CENP-H PF05837.12 EPE36371.1 - 0.3 11.5 0.1 0.3 11.5 0.1 2.2 2 1 0 2 2 2 0 Centromere protein H (CENP-H) ADIP PF11559.8 EPE36371.1 - 3 7.9 7.4 1 9.4 0.5 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CAP59_mtransfer PF11735.8 EPE36372.1 - 2.1e-78 263.4 0.0 2.6e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 p450 PF00067.22 EPE36373.1 - 7.5e-41 140.3 0.0 1.1e-40 139.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TspO_MBR PF03073.15 EPE36374.1 - 3.7e-44 150.0 4.5 4.6e-44 149.8 4.5 1.1 1 0 0 1 1 1 1 TspO/MBR family CRISPR_Cas6 PF10040.9 EPE36374.1 - 0.13 12.9 0.1 0.31 11.7 0.1 1.7 1 1 0 1 1 1 0 CRISPR-associated endoribonuclease Cas6 Acetyltransf_7 PF13508.7 EPE36377.1 - 1.2e-07 32.0 0.0 1.9e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE36377.1 - 6.8e-07 29.5 0.0 1.2e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE36377.1 - 1.4e-06 28.2 0.0 2.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE36377.1 - 0.013 15.4 0.0 0.031 14.2 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 EPE36377.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ribosomal_S24e PF01282.19 EPE36377.1 - 0.19 11.7 0.0 0.78 9.7 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S24e DUF3546 PF12066.8 EPE36378.1 - 3.2e-33 114.2 2.8 3.2e-33 114.2 2.8 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 EPE36378.1 - 5.6e-13 48.5 0.3 1.2e-12 47.4 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 EPE36378.1 - 3e-10 40.8 3.9 1.1e-09 39.0 3.9 2.1 1 1 0 1 1 1 1 Arsenite-resistance protein 2 Ribosomal_60s PF00428.19 EPE36378.1 - 0.79 10.4 8.9 1.1 9.8 2.3 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Tubulin PF00091.25 EPE36379.1 - 6.3e-65 219.1 0.0 8.7e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EPE36379.1 - 3.3e-43 146.9 0.0 5e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EPE36379.1 - 0.0033 17.1 0.0 0.0061 16.3 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Cpn60_TCP1 PF00118.24 EPE36380.1 - 8.5e-148 493.0 16.9 9.6e-148 492.8 16.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.29 EPE36381.1 - 1.3e-40 138.9 0.0 2.2e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPE36381.1 - 8e-07 28.8 0.0 2.1e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EPE36381.1 - 0.00011 22.5 0.0 0.0069 16.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EPE36381.1 - 0.00013 22.0 0.1 0.00054 20.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EPE36381.1 - 0.00015 22.0 0.0 0.00051 20.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EPE36381.1 - 0.00085 19.7 0.1 0.013 15.9 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EPE36381.1 - 0.0017 17.6 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EPE36381.1 - 0.0077 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EPE36381.1 - 0.026 14.8 0.0 0.062 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EPE36381.1 - 0.032 13.7 0.0 0.099 12.2 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EPE36381.1 - 0.044 13.9 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EPE36381.1 - 0.062 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 EPE36381.1 - 0.085 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EPE36381.1 - 0.095 12.4 0.0 0.28 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EPE36381.1 - 0.14 12.7 0.0 0.5 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EPE36381.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EPE36381.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF3818 PF12825.7 EPE36382.1 - 3.7e-131 437.2 6.9 6e-131 436.5 6.9 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EPE36382.1 - 2.1e-39 134.5 1.5 3.7e-39 133.7 1.5 1.4 1 0 0 1 1 1 1 PX-associated PX PF00787.24 EPE36382.1 - 5.5e-16 58.6 0.2 1.9e-14 53.6 0.0 3.4 4 1 0 4 4 4 1 PX domain GFD1 PF17331.2 EPE36382.1 - 0.64 10.3 3.7 0.33 11.2 0.7 2.1 2 0 0 2 2 2 0 GFD1 mRNA transport factor MCPsignal PF00015.21 EPE36383.1 - 0.016 15.0 1.2 0.029 14.2 0.6 1.7 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SLATT_5 PF18160.1 EPE36383.1 - 0.034 13.5 1.8 0.8 9.0 0.1 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF2660 PF10859.8 EPE36383.1 - 0.15 12.6 0.4 0.39 11.2 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2660) OapA_N PF08525.11 EPE36383.1 - 0.46 10.5 4.4 0.62 10.1 1.2 2.2 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif Fib_alpha PF08702.10 EPE36383.1 - 0.58 10.3 2.3 2.1 8.5 2.1 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.11 EPE36383.1 - 1.1 9.9 4.3 0.61 10.7 0.9 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal SelP_N PF04592.14 EPE36383.1 - 3.2 7.1 9.7 5.5 6.3 9.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Cgr1 PF03879.14 EPE36384.1 - 2.4e-32 111.5 35.9 2.7e-32 111.3 35.9 1.0 1 0 0 1 1 1 1 Cgr1 family CDC27 PF09507.10 EPE36384.1 - 0.86 8.9 25.7 0.94 8.8 25.7 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pal1 PF08316.11 EPE36384.1 - 3.4 8.4 5.5 4.1 8.1 5.5 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein VIR_N PF15912.5 EPE36384.1 - 4.9 6.7 10.4 5.6 6.5 10.4 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Mito_carr PF00153.27 EPE36385.1 - 6.6e-59 195.9 0.3 4.2e-19 68.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CHB_HEX_C PF03174.13 EPE36386.1 - 0.15 12.0 0.1 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain 5_nucleotid_C PF02872.18 EPE36387.1 - 4.3e-32 111.5 0.7 7.9e-32 110.7 0.1 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EPE36387.1 - 3.1e-11 44.2 0.7 5.7e-11 43.3 0.4 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase YmdB PF13277.6 EPE36387.1 - 0.005 16.2 0.1 0.014 14.8 0.1 1.7 2 0 0 2 2 2 1 YmdB-like protein DUF3425 PF11905.8 EPE36388.1 - 6e-22 77.9 0.1 1.1e-21 77.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) TFIIA_gamma_N PF02268.16 EPE36388.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain Draxin PF15550.6 EPE36388.1 - 0.15 11.9 2.0 0.21 11.4 2.0 1.1 1 0 0 1 1 1 0 Draxin bZIP_1 PF00170.21 EPE36388.1 - 1.4 9.1 7.2 2.5 8.2 7.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor HET PF06985.11 EPE36389.1 - 9e-23 81.2 1.0 9e-23 81.2 1.0 1.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Aldedh PF00171.22 EPE36390.1 - 4.6e-138 460.6 0.0 5.4e-138 460.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EPE36390.1 - 0.041 12.9 0.0 0.18 10.8 0.0 1.9 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) SET PF00856.28 EPE36391.1 - 3.5e-11 43.8 0.0 6.9e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 EPE36391.1 - 4.8e-10 39.4 10.7 4.8e-10 39.4 10.7 1.8 2 0 0 2 2 2 1 MYND finger HET PF06985.11 EPE36392.1 - 2e-27 96.3 1.1 5.2e-27 95.0 1.1 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_C97 PF05903.14 EPE36393.1 - 0.00026 20.9 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain FAD_binding_2 PF00890.24 EPE36394.1 - 1.3e-125 419.8 2.4 1.6e-125 419.5 2.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EPE36394.1 - 4.7e-44 149.5 0.4 7.1e-44 148.9 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 EPE36394.1 - 1.2e-05 24.6 1.4 0.017 14.2 2.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EPE36394.1 - 3.5e-05 23.2 1.0 0.0015 17.8 0.4 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE36394.1 - 7e-05 22.2 0.2 0.032 13.5 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EPE36394.1 - 0.0025 17.1 0.7 0.0058 15.9 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EPE36394.1 - 0.055 13.0 1.8 0.21 11.1 1.7 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EPE36394.1 - 0.083 11.6 1.0 0.26 9.9 0.2 2.2 3 0 0 3 3 3 0 HI0933-like protein CDH-cyt PF16010.5 EPE36395.1 - 4.9e-49 166.5 0.8 8.2e-49 165.7 0.8 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 EPE36395.1 - 3.9e-25 88.8 0.1 8.6e-25 87.7 0.1 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE36395.1 - 4.1e-18 66.3 0.1 9.3e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.18 EPE36395.1 - 4.4e-07 29.8 2.4 4.4e-07 29.8 2.4 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain FAD_binding_2 PF00890.24 EPE36395.1 - 1.3e-05 24.5 0.6 0.0017 17.5 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EPE36395.1 - 0.00011 21.9 0.3 0.00048 19.8 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EPE36395.1 - 0.00014 20.7 0.3 0.00031 19.6 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EPE36395.1 - 0.00086 19.5 0.1 0.0041 17.3 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EPE36395.1 - 0.0015 17.9 0.6 0.015 14.6 0.8 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPE36395.1 - 0.0032 16.7 0.1 0.0075 15.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE36395.1 - 0.006 17.1 0.1 0.2 12.2 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE36395.1 - 0.0065 15.6 0.2 0.011 14.8 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 EPE36395.1 - 0.016 14.3 0.2 0.25 10.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EPE36395.1 - 0.054 12.7 0.1 0.09 12.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain ELMO_CED12 PF04727.13 EPE36396.1 - 2.6e-52 177.5 0.1 5.1e-52 176.6 0.1 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 EPE36396.1 - 1.8e-39 135.4 0.2 9.6e-39 133.0 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain DUF3361 PF11841.8 EPE36396.1 - 6e-15 55.5 0.0 1.5e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) MS_channel PF00924.18 EPE36397.1 - 8.9e-23 80.9 1.0 1.6e-22 80.1 1.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EPE36397.1 - 0.0042 16.5 0.1 0.011 15.2 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EPE36397.1 - 0.0043 16.9 0.0 0.015 15.2 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EPE36397.1 - 0.009 15.5 0.0 0.029 13.9 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EPE36397.1 - 0.011 16.2 0.1 0.029 14.8 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair APH PF01636.23 EPE36398.1 - 3.7e-13 49.9 0.0 1.4e-12 48.0 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE36398.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 EPE36398.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 EPE36398.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Abhydrolase_6 PF12697.7 EPE36399.1 - 6.6e-12 46.5 5.4 1.1e-11 45.7 5.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE36399.1 - 1.5e-08 34.2 0.2 3.5e-08 33.0 0.2 1.6 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE36399.1 - 4.2e-08 33.2 0.3 7.1e-08 32.4 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EPE36399.1 - 2.4e-05 24.3 0.1 3.4e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPE36399.1 - 0.0081 15.7 0.5 0.015 14.8 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family zf-GRF PF06839.12 EPE36401.1 - 1.4e-11 44.3 4.4 3.4e-11 43.1 4.4 1.7 1 0 0 1 1 1 1 GRF zinc finger FlgH PF02107.16 EPE36401.1 - 0.013 15.2 0.1 0.022 14.4 0.0 1.5 2 0 0 2 2 2 0 Flagellar L-ring protein TSC22 PF01166.18 EPE36401.1 - 0.14 12.5 1.2 4.4 7.7 0.2 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF5102 PF17104.5 EPE36401.1 - 0.29 11.1 6.4 3.9 7.4 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) PKcGMP_CC PF16808.5 EPE36401.1 - 0.34 10.8 2.0 0.75 9.7 2.0 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Nucleoporin_FG PF13634.6 EPE36401.1 - 3.1 8.7 8.7 0.29 12.0 1.9 2.5 3 0 0 3 3 3 0 Nucleoporin FG repeat region DUF563 PF04577.14 EPE36402.1 - 2.3e-26 93.2 0.0 4.7e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Yippee-Mis18 PF03226.14 EPE36403.1 - 0.00022 21.4 1.2 0.0027 17.9 0.2 2.7 2 1 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Spc7 PF08317.11 EPE36403.1 - 0.096 11.5 8.9 0.26 10.1 1.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 EPE36403.1 - 0.27 10.6 8.2 0.55 9.5 8.2 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding KxDL PF10241.9 EPE36403.1 - 0.85 9.9 4.4 27 5.2 0.3 3.1 2 1 0 3 3 3 0 Uncharacterized conserved protein Rx_N PF18052.1 EPE36403.1 - 1.8 8.9 7.1 28 5.1 0.8 3.5 2 1 1 3 3 3 0 Rx N-terminal domain Fib_alpha PF08702.10 EPE36403.1 - 1.9 8.6 7.5 2.7 8.2 0.8 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 EPE36403.1 - 4.2 5.2 5.5 1.3 6.8 2.0 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.11 EPE36403.1 - 6.5 7.4 8.3 21 5.7 0.7 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal RNase_T PF00929.24 EPE36404.1 - 9.6e-08 32.7 0.0 2.7e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Exonuclease Catalase PF00199.19 EPE36406.1 - 3.1e-167 556.5 0.0 3.8e-167 556.2 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 EPE36406.1 - 8.5e-45 152.1 0.7 1.3e-44 151.5 0.7 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 EPE36406.1 - 2.9e-13 49.8 0.0 6.6e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive His_Phos_1 PF00300.22 EPE36407.1 - 5e-18 65.5 0.2 2.1e-16 60.2 0.2 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NACHT PF05729.12 EPE36408.1 - 4.6e-09 36.4 0.0 1.4e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EPE36408.1 - 0.00022 21.7 0.0 0.0021 18.4 0.0 2.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EPE36408.1 - 0.00077 19.8 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EPE36408.1 - 0.012 16.1 0.6 0.04 14.4 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 EPE36408.1 - 0.048 14.2 0.1 0.2 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EPE36408.1 - 0.054 13.2 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EPE36408.1 - 0.081 12.1 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain SesA PF17107.5 EPE36408.1 - 0.085 13.0 0.9 0.28 11.4 0.5 2.2 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases RNA_helicase PF00910.22 EPE36408.1 - 0.14 12.5 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Ank PF00023.30 EPE36408.1 - 0.17 12.4 0.0 3.6 8.2 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat IBR PF01485.21 EPE36409.1 - 1.7e-11 44.1 37.6 1.6e-08 34.6 6.7 3.1 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain CFEM PF05730.11 EPE36410.1 - 4.4e-15 55.5 13.9 7.1e-15 54.9 13.9 1.3 1 0 0 1 1 1 1 CFEM domain STE2 PF02116.15 EPE36410.1 - 0.025 13.9 8.4 0.013 14.8 6.2 1.6 2 0 0 2 2 2 0 Fungal pheromone mating factor STE2 GPCR Methyltransf_23 PF13489.6 EPE36411.1 - 1.5e-13 50.9 0.0 2e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE36411.1 - 1e-11 44.9 0.0 1.3e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE36411.1 - 3.2e-11 43.8 0.0 5.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE36411.1 - 1.5e-09 38.4 0.0 3.4e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE36411.1 - 2.5e-09 37.8 0.0 4.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPE36411.1 - 2.7e-05 23.6 0.0 4.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EPE36411.1 - 3.8e-05 23.3 0.0 9.1e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 EPE36411.1 - 0.0033 16.6 0.0 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase AdoMet_MTase PF07757.13 EPE36411.1 - 0.072 13.4 0.0 0.17 12.2 0.0 1.6 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase HET PF06985.11 EPE36412.1 - 2.7e-18 66.7 0.0 5.4e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SUI1 PF01253.22 EPE36413.1 - 1.6e-26 92.6 0.7 2.5e-26 92.0 0.2 1.6 2 0 0 2 2 2 1 Translation initiation factor SUI1 Img2 PF05046.14 EPE36413.1 - 0.031 14.6 0.1 0.052 13.9 0.1 1.5 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Pox_RNA_Pol_19 PF05320.12 EPE36413.1 - 0.074 13.0 0.3 0.14 12.2 0.3 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Nbl1_Borealin_N PF10444.9 EPE36414.1 - 3e-19 68.4 2.9 5.9e-19 67.5 2.9 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.6 EPE36415.1 - 1.7e-28 99.4 0.0 3.5e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EPE36415.1 - 7e-12 45.9 0.2 9.8e-12 45.5 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 EPE36415.1 - 5.7e-08 32.8 0.0 7.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 EPE36415.1 - 0.0078 16.1 1.1 0.022 14.7 1.1 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif RNA_pol_Rpb4 PF03874.16 EPE36416.1 - 2.2e-24 86.1 4.1 3e-24 85.7 4.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 RhoGEF67_u2 PF16614.5 EPE36416.1 - 0.1 12.6 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 DUF3349 PF11829.8 EPE36416.1 - 0.49 11.2 2.9 0.84 10.5 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) F-box-like PF12937.7 EPE36417.1 - 0.041 13.8 0.1 0.12 12.3 0.1 1.9 1 0 0 1 1 1 0 F-box-like CD34_antigen PF06365.12 EPE36418.1 - 0.069 12.7 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 CD34/Podocalyxin family Mid2 PF04478.12 EPE36418.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.6 EPE36418.1 - 0.29 11.0 0.9 0.88 9.5 0.9 1.8 1 0 0 1 1 1 0 TMEM154 protein family ADH_N PF08240.12 EPE36419.1 - 2.1e-20 72.6 2.2 3.8e-20 71.8 2.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPE36419.1 - 2e-12 47.2 0.0 3.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EPE36419.1 - 0.00023 20.6 0.1 0.00036 19.9 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EPE36419.1 - 0.0036 16.6 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.22 EPE36419.1 - 0.021 15.7 0.0 0.034 15.0 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 EPE36419.1 - 0.15 11.9 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_45 PF02015.16 EPE36420.1 - 1.2e-78 263.8 21.0 2.1e-78 263.1 21.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 CBM_1 PF00734.18 EPE36420.1 - 2.5e-10 40.1 8.9 2.5e-10 40.1 8.9 4.3 4 0 0 4 4 4 1 Fungal cellulose binding domain DUF4871 PF16167.5 EPE36420.1 - 0.27 11.3 4.5 0.49 10.4 4.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4871) Orthopox_35kD PF02250.15 EPE36422.1 - 0.0099 15.6 0.7 0.015 15.0 0.7 1.2 1 0 0 1 1 1 1 35kD major secreted virus protein Alpha_GJ PF03229.13 EPE36422.1 - 0.014 15.9 11.4 0.014 15.9 11.4 1.9 2 0 0 2 2 2 0 Alphavirus glycoprotein J VIR_N PF15912.5 EPE36422.1 - 0.075 12.6 2.6 0.12 11.9 2.6 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal FSA_C PF10479.9 EPE36422.1 - 9.7 4.2 8.4 13 3.8 8.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Alg6_Alg8 PF03155.15 EPE36423.1 - 1.9e-131 439.4 25.3 1.7e-83 281.2 7.0 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family MFS_1 PF07690.16 EPE36424.1 - 8.5e-38 130.2 55.5 8.5e-38 130.2 55.5 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE36424.1 - 1.4e-10 40.6 15.1 1.4e-10 40.6 15.1 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter GPI-anchored PF10342.9 EPE36425.1 - 1.9e-06 28.5 0.4 1.9e-06 28.5 0.4 4.2 3 2 2 5 5 5 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.6 EPE36425.1 - 0.0054 16.5 0.9 0.0054 16.5 0.9 2.5 2 2 0 2 2 2 1 Protein of unknown function (DUF4448) Ank_2 PF12796.7 EPE36426.1 - 8.7e-35 119.2 0.0 3.6e-12 46.7 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE36426.1 - 6.6e-29 96.7 3.3 1.2e-05 25.3 0.0 8.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 EPE36426.1 - 4.5e-27 94.1 1.4 1.3e-06 28.8 0.0 6.1 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPE36426.1 - 3.5e-25 87.7 2.0 0.00075 19.7 0.0 7.3 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 EPE36426.1 - 7.4e-20 70.5 9.3 0.0037 17.6 0.0 8.2 7 1 1 8 8 8 6 Ankyrin repeat NmrA PF05368.13 EPE36427.1 - 9.1e-50 169.4 1.1 1.1e-49 169.1 1.1 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE36427.1 - 1.1e-13 51.5 0.0 1.5e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EPE36427.1 - 1.3e-07 30.9 0.0 1.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPE36427.1 - 0.00057 19.4 0.0 0.00077 19.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.8 EPE36428.1 - 6.9e-06 25.1 1.3 1e-05 24.5 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Neprosin PF03080.15 EPE36429.1 - 1.8e-41 141.9 6.7 2.6e-41 141.4 6.7 1.2 1 0 0 1 1 1 1 Neprosin TPR_12 PF13424.6 EPE36432.1 - 3.9e-34 116.8 10.8 1.4e-12 47.7 0.0 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 EPE36432.1 - 2.1e-30 103.7 8.4 7.5e-07 28.8 0.0 7.8 7 0 0 7 7 7 5 Tetratricopeptide repeat HET PF06985.11 EPE36432.1 - 1e-12 48.6 6.5 2e-10 41.2 0.3 3.2 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.22 EPE36432.1 - 3.2e-11 42.9 0.0 1.3e-10 40.9 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain TPR_MalT PF17874.1 EPE36432.1 - 1.5e-08 34.5 3.7 1.6e-08 34.4 1.2 2.0 1 1 0 2 2 2 1 MalT-like TPR region NACHT PF05729.12 EPE36432.1 - 7.5e-07 29.2 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain TPR_2 PF07719.17 EPE36432.1 - 9.8e-06 25.3 13.0 0.041 14.0 2.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPE36432.1 - 1.5e-05 25.4 0.9 1.6 9.8 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EPE36432.1 - 4.8e-05 23.1 2.4 0.023 14.7 0.4 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 EPE36432.1 - 9.3e-05 22.7 0.1 0.41 11.4 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EPE36432.1 - 0.00035 20.3 8.6 0.045 13.6 1.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.9 EPE36432.1 - 0.0047 16.7 1.8 0.045 13.5 0.1 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) AAA_22 PF13401.6 EPE36432.1 - 0.0095 16.2 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain MIT PF04212.18 EPE36432.1 - 0.051 13.6 0.1 0.24 11.5 0.1 2.1 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 EPE36432.1 - 0.09 13.4 3.9 8.5 7.1 0.3 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPE36432.1 - 0.13 12.9 2.1 0.86 10.4 0.4 3.5 3 0 0 3 3 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EPE36432.1 - 7.5 7.0 10.0 12 6.4 0.8 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat adh_short PF00106.25 EPE36433.1 - 4.4e-36 124.2 4.2 6.4e-36 123.7 1.5 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE36433.1 - 2.2e-33 115.8 2.5 3.7e-32 111.8 2.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE36433.1 - 1.6e-08 34.7 2.0 1.7e-08 34.6 0.5 1.7 2 0 0 2 2 2 1 KR domain Glycogen_syn PF05693.13 EPE36433.1 - 0.013 14.1 0.0 0.019 13.6 0.0 1.1 1 0 0 1 1 1 0 Glycogen synthase DUF1776 PF08643.10 EPE36433.1 - 0.021 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TrkA_N PF02254.18 EPE36433.1 - 0.024 14.9 0.2 0.045 14.0 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 EPE36433.1 - 0.074 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EPE36433.1 - 0.076 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPE36433.1 - 0.12 11.8 0.2 0.32 10.4 0.1 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 EPE36434.1 - 2.3e-27 96.0 0.0 4.5e-27 95.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE36434.1 - 2.2e-08 33.7 0.0 3.7e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPE36434.1 - 0.0033 17.4 0.2 0.0033 17.4 0.2 3.2 3 1 0 3 3 3 1 Phosphotransferase enzyme family zf-RING_2 PF13639.6 EPE36436.1 - 2.2e-05 24.7 6.8 2.2e-05 24.7 6.8 2.4 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EPE36436.1 - 0.00024 21.1 2.1 0.00085 19.3 2.1 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EPE36436.1 - 0.00062 19.7 4.8 0.0016 18.4 4.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EPE36436.1 - 0.00085 19.1 2.0 0.0023 17.8 2.0 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EPE36436.1 - 0.01 15.9 1.2 0.037 14.2 1.2 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EPE36436.1 - 0.013 15.4 7.9 0.16 11.8 8.1 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE36436.1 - 0.036 14.0 3.0 0.12 12.3 3.0 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE36436.1 - 0.069 13.0 7.7 0.46 10.4 7.7 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EPE36436.1 - 0.17 11.7 5.0 4.9 7.0 5.0 2.7 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 EPE36437.1 - 1.2e-06 28.8 6.7 3e-06 27.5 6.7 1.7 1 1 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EPE36437.1 - 4e-06 26.6 2.2 8.2e-06 25.6 2.2 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EPE36437.1 - 4.2e-05 23.5 5.2 6.9e-05 22.8 4.1 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EPE36437.1 - 9.5e-05 22.3 6.2 0.00019 21.3 6.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EPE36437.1 - 0.00069 19.4 6.7 0.0043 16.9 6.9 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPE36437.1 - 0.0019 18.0 2.6 0.0049 16.7 2.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPE36437.1 - 0.007 16.5 2.1 0.007 16.5 2.1 2.9 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 EPE36437.1 - 0.041 13.2 0.7 0.068 12.5 0.3 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_11 PF17123.5 EPE36437.1 - 0.19 11.5 5.0 5.6 6.8 5.0 2.5 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 EPE36437.1 - 0.32 10.9 9.7 2.5 8.0 9.7 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPE36437.1 - 0.72 10.2 5.1 1.4 9.2 5.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain SAP PF02037.27 EPE36441.1 - 0.068 12.9 2.8 1.8 8.4 0.0 4.1 5 0 0 5 5 5 0 SAP domain PaaX_C PF08223.11 EPE36441.1 - 0.086 13.1 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain DUF4817 PF16087.5 EPE36441.1 - 0.11 12.3 0.0 0.73 9.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) DUF1100 PF06500.11 EPE36442.1 - 7.4e-10 38.2 0.0 9.7e-10 37.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.18 EPE36442.1 - 0.00026 20.7 0.1 0.00047 19.8 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EPE36442.1 - 0.002 17.7 0.1 0.0053 16.3 0.1 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EPE36442.1 - 0.082 12.5 0.0 0.44 10.1 0.0 2.0 1 1 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 EPE36442.1 - 0.13 11.5 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF1749 PF08538.10 EPE36442.1 - 0.18 10.8 0.0 3.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) ZZ PF00569.17 EPE36443.1 - 2.6e-05 24.0 0.3 4.1e-05 23.3 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type dCMP_cyt_deam_1 PF00383.23 EPE36447.1 - 0.013 15.4 0.0 0.033 14.1 0.0 1.6 2 1 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region SAP PF02037.27 EPE36449.1 - 3.1e-10 39.6 24.6 0.00046 19.9 0.4 8.0 10 0 0 10 10 10 3 SAP domain HeH PF12949.7 EPE36449.1 - 0.00018 21.1 0.1 0.001 18.7 0.0 2.4 2 0 0 2 2 2 1 HeH/LEM domain YwpF PF14183.6 EPE36449.1 - 0.0042 17.1 0.1 0.0088 16.1 0.1 1.5 1 0 0 1 1 1 1 YwpF-like protein DUF1133 PF06576.11 EPE36449.1 - 0.066 12.6 0.1 14 5.0 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1133) LmjF365940-deam PF14421.6 EPE36449.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Laterosporulin PF17861.1 EPE36449.1 - 0.19 12.2 0.1 0.41 11.1 0.1 1.5 1 0 0 1 1 1 0 Laterosporulin defensin-like peptide Pkinase PF00069.25 EPE36450.1 - 2.1e-26 92.9 0.0 3.8e-26 92.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE36450.1 - 1.1e-09 38.0 0.0 2.8e-09 36.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EPE36450.1 - 0.003 16.9 0.0 0.0062 15.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPE36450.1 - 0.031 14.2 0.1 0.1 12.5 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family adh_short PF00106.25 EPE36451.1 - 3.2e-14 52.8 0.0 4.1e-11 42.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EPE36451.1 - 3.2e-06 27.2 0.0 7.4e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.6 EPE36451.1 - 1.1e-05 25.1 0.0 0.0018 17.9 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF4188 PF13826.6 EPE36452.1 - 1.2e-23 83.7 0.0 1.6e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 EPE36452.1 - 0.00028 20.4 0.1 0.00037 20.0 0.1 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase Carb_anhydrase PF00194.21 EPE36454.1 - 1.4e-37 129.7 0.1 1.9e-37 129.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase RRM_1 PF00076.22 EPE36456.1 - 1.6e-20 72.7 0.0 1.5e-12 47.1 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.29 EPE36457.1 - 1.3e-20 73.9 0.0 3.1e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE36457.1 - 1.9e-18 66.8 0.0 1.4e-14 54.4 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EPE36457.1 - 1.6e-07 32.0 0.1 3.3e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 RecQ zinc-binding SNF2_N PF00176.23 EPE36457.1 - 0.05 12.3 0.0 0.091 11.5 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Peptidase_S41 PF03572.18 EPE36458.1 - 1.5e-06 27.8 0.0 9.3e-06 25.3 0.0 2.0 1 1 0 1 1 1 1 Peptidase family S41 HNH_2 PF13391.6 EPE36459.1 - 0.064 13.4 0.2 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 HNH endonuclease SRR1 PF07985.12 EPE36459.1 - 0.071 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 SRR1 DUF1515 PF07439.11 EPE36459.1 - 0.076 13.0 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) FlxA PF14282.6 EPE36460.1 - 0.16 11.9 4.8 0.23 11.5 4.6 1.4 1 1 0 1 1 1 0 FlxA-like protein DivIC PF04977.15 EPE36460.1 - 0.62 9.9 6.1 1.1 9.0 6.1 1.4 1 0 0 1 1 1 0 Septum formation initiator DASH_Spc34 PF08657.10 EPE36460.1 - 1.3 8.7 6.9 1.6 8.4 6.9 1.0 1 0 0 1 1 1 0 DASH complex subunit Spc34 p450 PF00067.22 EPE36461.1 - 9.4e-70 235.6 0.0 1.1e-69 235.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.22 EPE36462.1 - 8.1e-40 134.5 0.0 9.2e-19 67.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPE36462.1 - 1.1e-05 25.5 0.0 0.082 13.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EPE36462.1 - 0.00015 21.7 0.0 0.064 13.3 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Peptidase_U49 PF10463.9 EPE36462.1 - 0.36 10.6 2.9 0.93 9.2 2.9 1.6 1 0 0 1 1 1 0 Peptidase U49 NDUFB10 PF10249.9 EPE36463.1 - 0.0075 16.8 0.0 0.0082 16.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.14 EPE36463.1 - 0.12 13.1 0.0 0.17 12.6 0.0 1.2 1 0 0 1 1 1 0 HWE histidine kinase Ribosomal_L37 PF08561.10 EPE36464.1 - 1.8e-38 131.8 0.1 2.5e-38 131.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 TAFII55_N PF04658.13 EPE36465.1 - 3.5e-50 169.9 0.0 6.9e-50 168.9 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region SPATA1_C PF15743.5 EPE36465.1 - 0.38 10.8 4.5 0.68 10.0 4.5 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus Gal4_dimer PF03902.13 EPE36465.1 - 2 8.6 4.2 3.4 7.9 2.3 2.3 2 0 0 2 2 2 0 Gal4-like dimerisation domain Bromo_TP PF07524.13 EPE36466.1 - 8.9e-09 35.2 0.0 1.7e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EPE36466.1 - 5.2e-05 23.3 0.0 9.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TFIID_30kDa PF03540.13 EPE36466.1 - 0.026 14.4 0.1 0.057 13.4 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit DUF148 PF02520.17 EPE36467.1 - 0.052 13.6 0.8 0.079 13.1 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 YqzE PF14038.6 EPE36467.1 - 0.22 11.5 0.8 0.4 10.7 0.8 1.3 1 0 0 1 1 1 0 YqzE-like protein BRO1 PF03097.18 EPE36468.1 - 1.7e-08 33.7 0.0 2.5e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Fungal_trans_2 PF11951.8 EPE36470.1 - 2.9e-05 23.1 0.0 8.9e-05 21.5 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.13 EPE36471.1 - 1e-19 71.1 0.0 1.3e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EPE36471.1 - 0.012 16.1 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EPE36471.1 - 0.19 11.2 0.0 12 5.3 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Viral_DNA_bp PF00747.17 EPE36472.1 - 0.024 11.8 0.7 0.034 11.3 0.7 1.1 1 0 0 1 1 1 0 ssDNA binding protein F-box-like PF12937.7 EPE36472.1 - 0.1 12.5 0.2 0.1 12.5 0.2 1.8 2 0 0 2 2 2 0 F-box-like Pkinase PF00069.25 EPE36474.1 - 2.3e-20 73.1 0.0 4.2e-19 68.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE36474.1 - 0.00011 21.6 0.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2153 PF09921.9 EPE36474.1 - 0.025 14.4 1.7 2.9 7.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2153) Pkinase_fungal PF17667.1 EPE36474.1 - 0.037 12.8 0.1 0.051 12.3 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase MBOAT_2 PF13813.6 EPE36475.1 - 0.01 16.1 2.8 0.094 13.0 0.4 2.8 3 0 0 3 3 3 0 Membrane bound O-acyl transferase family Fungal_trans_2 PF11951.8 EPE36475.1 - 0.015 14.1 0.3 0.022 13.6 0.3 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE36475.1 - 0.041 14.0 5.4 0.093 12.9 5.4 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Tannase PF07519.11 EPE36476.1 - 9.3e-78 262.2 0.0 1.7e-77 261.4 0.0 1.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 EPE36476.1 - 0.00096 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPE36476.1 - 0.0063 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EPE36476.1 - 0.13 11.7 0.0 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family FAM178 PF14816.6 EPE36479.1 - 0.13 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 p450 PF00067.22 EPE36480.1 - 2.6e-29 102.3 0.0 3.2e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyltransferase PF01553.21 EPE36481.1 - 2.8e-20 72.3 0.0 4.1e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF2235 PF09994.9 EPE36482.1 - 1.6e-81 273.9 0.1 2.2e-81 273.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 EPE36482.1 - 0.025 14.5 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal An_peroxidase PF03098.15 EPE36483.1 - 2.3e-31 109.0 0.1 2e-18 66.3 0.1 4.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 EPE36483.1 - 4.5e-08 32.3 0.1 4e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 HsbA PF12296.8 EPE36484.1 - 2.4e-17 63.5 1.9 3.2e-17 63.1 1.9 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Nuc_deoxyrib_tr PF05014.15 EPE36485.1 - 1.2e-32 112.7 0.0 1.5e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Pro-kuma_activ PF09286.11 EPE36486.1 - 1.6e-30 106.3 0.0 1.2e-26 93.7 0.0 2.3 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EPE36486.1 - 2e-07 30.6 0.2 6.2e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Subtilase family Mago-bind PF09282.10 EPE36486.1 - 0.034 14.0 0.1 0.088 12.7 0.1 1.7 1 0 0 1 1 1 0 Mago binding CDH-cyt PF16010.5 EPE36487.1 - 2.4e-16 59.9 1.4 4.4e-16 59.1 1.4 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EPE36487.1 - 6.8e-12 45.7 8.0 1.4e-11 44.7 8.0 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 EPE36487.1 - 2e-06 28.0 0.1 3.7e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 EPE36487.1 - 0.0012 18.6 4.8 0.0014 18.4 3.3 1.8 1 1 1 2 2 2 2 Domain of unknown function (DUF2427) DUF4079 PF13301.6 EPE36487.1 - 0.13 12.4 10.5 1.6 8.9 5.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Alpha_GJ PF03229.13 EPE36487.1 - 1.8 9.1 10.7 0.66 10.5 6.7 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF4662 PF15578.6 EPE36488.1 - 0.044 13.6 0.3 0.087 12.6 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) HET PF06985.11 EPE36489.1 - 5.3e-25 88.5 0.0 9.8e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4969 PF16339.5 EPE36489.1 - 0.22 11.9 0.3 1.7 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) DPBB_1 PF03330.18 EPE36490.1 - 0.002 18.4 0.0 0.0039 17.4 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Borrelia_P83 PF05262.11 EPE36490.1 - 0.0031 16.1 16.8 0.0037 15.8 16.8 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Red1 PF07964.11 EPE36490.1 - 1.3 7.2 25.4 2.1 6.5 25.4 1.3 1 0 0 1 1 1 0 Rec10 / Red1 NPR3 PF03666.13 EPE36490.1 - 5 5.8 17.2 8.7 5.0 17.2 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Mitofilin PF09731.9 EPE36490.1 - 6 5.6 34.4 7.7 5.2 34.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pkinase PF00069.25 EPE36491.1 - 4.5e-67 226.2 0.0 5.6e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE36491.1 - 4.7e-32 111.3 0.0 6.6e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPE36491.1 - 0.0024 16.7 0.1 0.0038 16.1 0.1 1.5 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EPE36491.1 - 0.0055 15.7 0.1 0.0082 15.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EPE36491.1 - 0.0088 15.7 0.1 1.1 8.9 0.1 2.6 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EPE36491.1 - 0.0092 15.3 0.0 0.028 13.7 0.0 1.7 1 1 1 2 2 2 1 Kinase-like DUF4246 PF14033.6 EPE36492.1 - 1.6e-127 426.4 0.1 1.9e-127 426.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Chordopox_A13L PF05961.11 EPE36492.1 - 0.033 14.4 0.1 0.082 13.2 0.1 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein HET PF06985.11 EPE36495.1 - 2.2e-27 96.2 0.0 6.7e-27 94.6 0.0 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) APH PF01636.23 EPE36496.1 - 0.00038 20.5 0.0 0.0007 19.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family WSC PF01822.19 EPE36497.1 - 2.3e-16 59.7 8.4 2.3e-16 59.7 8.4 1.8 2 0 0 2 2 2 1 WSC domain HsbA PF12296.8 EPE36497.1 - 0.27 11.7 3.0 0.46 10.9 3.0 1.3 1 0 0 1 1 1 0 Hydrophobic surface binding protein A zf-C2H2_4 PF13894.6 EPE36498.1 - 2.1e-15 56.1 53.1 0.0092 16.7 2.4 8.4 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.26 EPE36498.1 - 1.4e-11 44.2 46.8 0.053 14.0 2.3 8.0 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EPE36498.1 - 2.2e-05 24.7 35.5 0.089 13.1 0.8 6.6 2 1 2 5 5 5 3 C2H2 type zinc-finger (2 copies) Elf1 PF05129.13 EPE36498.1 - 0.00015 21.8 0.9 0.00015 21.8 0.9 5.5 4 2 2 6 6 6 2 Transcription elongation factor Elf1 like zf-H2C2_5 PF13909.6 EPE36498.1 - 0.0045 16.7 1.4 0.0045 16.7 1.4 4.9 5 0 0 5 5 4 1 C2H2-type zinc-finger domain zf-Di19 PF05605.12 EPE36498.1 - 0.023 15.0 40.5 0.033 14.5 2.9 6.2 2 1 5 7 7 7 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 EPE36498.1 - 0.032 14.5 25.0 0.074 13.4 1.3 4.4 2 1 2 5 5 5 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 EPE36498.1 - 0.035 14.1 0.7 0.035 14.1 0.7 7.3 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE36498.1 - 0.05 13.9 42.6 0.11 12.8 0.3 7.6 8 0 0 8 8 7 0 Zinc-finger double-stranded RNA-binding DUF4764 PF15961.5 EPE36498.1 - 0.11 11.2 4.2 0.04 12.6 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4764) Spt46 PF17734.1 EPE36498.1 - 0.12 12.2 8.8 0.077 12.8 1.9 2.8 1 1 2 3 3 3 0 Spermatogenesis-associated protein 46 zf-C2H2_3rep PF18868.1 EPE36498.1 - 1.9 9.2 21.0 3.3 8.4 9.1 4.7 1 1 3 4 4 4 0 Zinc finger C2H2-type, 3 repeats Methyltransf_25 PF13649.6 EPE36499.1 - 1.1e-11 45.3 0.0 2.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EPE36499.1 - 4e-11 42.9 0.0 5.7e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EPE36499.1 - 6.3e-10 39.0 0.1 9.9e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPE36499.1 - 8.8e-08 32.7 0.0 1.8e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE36499.1 - 5.2e-07 29.6 0.0 7.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EPE36499.1 - 2.3e-06 26.7 0.1 3.3e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 EPE36499.1 - 4.2e-05 23.5 0.1 7.1e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EPE36499.1 - 4.8e-05 22.8 0.0 6.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EPE36499.1 - 0.00046 19.8 0.1 0.00074 19.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EPE36499.1 - 0.00052 19.4 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain PRMT5 PF05185.16 EPE36499.1 - 0.00082 19.3 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase FtsJ PF01728.19 EPE36499.1 - 0.0018 18.5 0.2 0.0025 17.9 0.2 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 EPE36499.1 - 0.002 18.8 0.0 0.0035 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EPE36499.1 - 0.014 15.1 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase TehB PF03848.14 EPE36499.1 - 0.034 13.5 0.2 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 EPE36499.1 - 0.036 13.7 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 EPE36499.1 - 0.04 13.3 0.8 0.11 11.8 0.2 2.0 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EPE36499.1 - 0.043 13.6 0.1 0.071 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EPE36499.1 - 0.054 13.5 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltrans_SAM PF10672.9 EPE36499.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase TFIIB PF00382.19 EPE36500.1 - 1.8e-22 79.1 0.1 5.2e-18 64.9 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EPE36500.1 - 3e-19 69.2 2.3 3e-19 69.2 2.3 3.6 3 0 0 3 3 3 2 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EPE36500.1 - 0.0026 17.2 0.6 0.0083 15.6 0.6 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EPE36500.1 - 0.071 12.9 0.2 0.19 11.5 0.0 1.7 2 0 0 2 2 2 0 Cyclin, N-terminal domain DUF3246 PF11596.8 EPE36501.1 - 1.2 8.6 19.0 1.5 8.2 18.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) CCDC106 PF15794.5 EPE36501.1 - 1.9 8.1 4.8 1.7 8.3 4.2 1.3 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 Fer4_19 PF06902.11 EPE36502.1 - 0.039 14.0 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster BCS1_N PF08740.11 EPE36503.1 - 8.5e-40 136.7 0.1 1.2e-39 136.2 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EPE36503.1 - 1.4e-16 61.1 0.0 2.5e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPE36503.1 - 0.00023 21.6 0.1 0.0029 18.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EPE36503.1 - 0.0028 17.2 0.0 0.0062 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EPE36503.1 - 0.0037 16.5 0.0 0.0067 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 EPE36503.1 - 0.0085 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EPE36503.1 - 0.012 15.9 0.0 0.096 13.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EPE36503.1 - 0.017 15.1 0.0 0.038 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EPE36503.1 - 0.019 14.8 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 EPE36503.1 - 0.028 14.9 0.0 0.066 13.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.6 EPE36503.1 - 0.03 14.8 0.1 0.58 10.6 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 EPE36503.1 - 0.03 14.1 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EPE36503.1 - 0.033 14.4 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 EPE36503.1 - 0.033 13.0 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase RNA_helicase PF00910.22 EPE36503.1 - 0.038 14.4 0.0 0.091 13.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase GTSE1_N PF15259.6 EPE36503.1 - 0.058 13.6 0.0 0.16 12.1 0.0 1.6 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 AAA_18 PF13238.6 EPE36503.1 - 0.065 13.8 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EPE36503.1 - 0.071 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EPE36503.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 EPE36503.1 - 0.16 11.9 0.0 0.57 10.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 EPE36503.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EPE36503.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 KaiC CHZ PF09649.10 EPE36504.1 - 6.5e-08 31.9 0.2 1.4e-07 30.9 0.2 1.6 1 0 0 1 1 1 1 Histone chaperone domain CHZ Gpr1_Fun34_YaaH PF01184.19 EPE36505.1 - 5.3e-22 78.5 20.2 6.6e-22 78.1 20.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Tetraspanin PF00335.20 EPE36505.1 - 2.2 7.9 8.8 0.98 9.1 6.0 1.7 1 1 0 1 1 1 0 Tetraspanin family Glyoxalase PF00903.25 EPE36506.1 - 3.9e-11 43.2 0.0 6.9e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EPE36506.1 - 4e-06 27.1 0.0 7.6e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EPE36506.1 - 0.064 13.2 0.0 7 6.6 0.0 2.7 3 0 0 3 3 3 0 Glyoxalase-like domain Glyco_hydro_2_N PF02837.18 EPE36507.1 - 1.5e-14 54.3 0.0 3.1e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 EPE36507.1 - 5.4e-11 42.1 0.0 9.9e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 EPE36507.1 - 2.1e-08 34.8 0.0 4.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 EPE36507.1 - 0.018 15.6 1.4 0.027 15.0 0.4 1.8 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain IBR PF01485.21 EPE36508.1 - 2.5e-15 56.4 19.4 6.5e-09 35.9 1.8 4.1 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain Pecanex_C PF05041.15 EPE36508.1 - 0.22 11.1 0.2 0.41 10.2 0.2 1.3 1 0 0 1 1 1 0 Pecanex protein (C-terminus) RibD_C PF01872.17 EPE36509.1 - 7.8e-32 110.7 0.0 9e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Transposase_mut PF00872.18 EPE36509.1 - 0.27 10.1 0.2 0.37 9.6 0.2 1.1 1 0 0 1 1 1 0 Transposase, Mutator family Bac_luciferase PF00296.20 EPE36510.1 - 8.6e-49 166.7 0.0 1.1e-48 166.3 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SRA1 PF07304.11 EPE36512.1 - 0.029 14.2 0.1 0.072 12.9 0.1 1.6 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) EST1 PF10374.9 EPE36512.1 - 1.3 9.7 3.9 1.7 9.3 0.1 2.4 2 1 0 2 2 2 0 Telomerase activating protein Est1 DUF2358 PF10184.9 EPE36513.1 - 0.0099 16.1 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 EPE36513.1 - 0.021 15.5 0.0 0.029 15.0 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain RE_XamI PF09572.10 EPE36513.1 - 0.037 13.7 0.0 0.054 13.2 0.0 1.1 1 0 0 1 1 1 0 XamI restriction endonuclease RicinB_lectin_2 PF14200.6 EPE36514.1 - 0.0061 17.3 2.2 0.55 11.0 0.2 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like NICE-1 PF15845.5 EPE36514.1 - 0.065 14.0 2.8 0.14 12.9 2.8 1.6 1 1 0 1 1 1 0 Cysteine-rich C-terminal 1 family HET PF06985.11 EPE36515.1 - 1.6e-21 77.2 0.0 2.7e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 EPE36517.1 - 4.2e-34 118.0 33.2 4.2e-34 118.0 33.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily ERCC4 PF02732.15 EPE36518.1 - 1.9e-26 93.1 0.1 4.7e-26 91.9 0.1 1.7 2 0 0 2 2 2 1 ERCC4 domain HHH_8 PF14716.6 EPE36518.1 - 0.0077 16.6 0.0 0.026 14.9 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain PGM_PMM_I PF02878.16 EPE36519.1 - 3.1e-19 69.1 0.1 1.1e-09 38.1 0.0 2.9 3 0 0 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EPE36519.1 - 4.9e-13 49.1 0.6 1.5e-12 47.5 0.6 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EPE36519.1 - 0.0014 18.8 0.1 0.0042 17.3 0.1 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EPE36519.1 - 0.06 14.0 1.3 5.1 7.8 0.5 3.2 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Dicty_REP PF05086.12 EPE36520.1 - 0.83 7.6 12.0 1.2 7.1 12.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DIOX_N PF14226.6 EPE36525.1 - 5e-20 72.4 0.1 9.1e-20 71.6 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPE36525.1 - 3.4e-10 40.3 0.0 6.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MTTB PF06253.11 EPE36525.1 - 0.17 9.8 0.0 0.27 9.2 0.0 1.2 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) MFS_1 PF07690.16 EPE36526.1 - 1.8e-23 83.1 31.0 1.8e-23 83.1 31.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3021 PF11457.8 EPE36526.1 - 4.2 7.7 12.7 0.38 11.1 5.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) Amdase PF17645.1 EPE36527.1 - 2.3e-14 53.5 0.1 4.3e-14 52.7 0.0 1.3 1 1 0 1 1 1 1 Arylmalonate decarboxylase FAD_binding_3 PF01494.19 EPE36528.1 - 2.2e-17 63.3 0.2 1.1e-16 61.0 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EPE36528.1 - 1.6e-05 24.4 0.1 0.0028 17.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPE36528.1 - 0.00012 22.2 0.2 0.00031 20.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE36528.1 - 0.00029 20.2 3.1 0.0014 18.0 1.3 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPE36528.1 - 0.0017 18.4 0.9 1.3 9.0 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 EPE36528.1 - 0.01 15.4 3.4 0.86 9.1 2.8 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPE36528.1 - 0.013 14.6 1.2 0.021 13.9 0.9 1.5 1 1 0 1 1 1 0 FAD binding domain Amidase02_C PF12123.8 EPE36528.1 - 0.086 12.5 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Fungal_trans PF04082.18 EPE36529.1 - 5.7e-21 74.7 1.1 1.3e-20 73.6 1.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE36529.1 - 0.0018 18.3 14.8 0.0039 17.3 14.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 EPE36530.1 - 2.3e-60 204.5 0.0 3.1e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE36530.1 - 1.7e-29 103.2 0.0 3.2e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EPE36530.1 - 0.00015 21.0 0.2 0.0003 20.0 0.2 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPE36530.1 - 0.0013 18.9 0.2 0.0034 17.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE36530.1 - 0.0014 18.3 1.3 0.014 15.0 0.9 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EPE36530.1 - 0.061 12.4 0.2 2.1 7.4 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 EPE36530.1 - 0.07 11.8 0.1 0.36 9.5 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 EPE36530.1 - 0.1 11.6 0.3 0.2 10.7 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain Transp_cyt_pur PF02133.15 EPE36531.1 - 4.3e-77 259.8 39.0 4.9e-77 259.6 39.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TGase_elicitor PF16683.5 EPE36531.1 - 0.048 12.4 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase elicitor HET PF06985.11 EPE36532.1 - 1.9e-26 93.2 0.0 3.9e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF835 PF05763.12 EPE36532.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF835) HET PF06985.11 EPE36533.1 - 4.7e-35 121.1 1.1 8.5e-35 120.2 0.5 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Aldedh PF00171.22 EPE36534.1 - 9.1e-152 505.8 0.2 1e-151 505.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EPE36534.1 - 0.011 15.2 0.0 0.067 12.6 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Acetyltransf_3 PF13302.7 EPE36536.1 - 5.4e-14 53.0 0.9 9.5e-14 52.2 0.9 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE36536.1 - 9.3e-07 29.1 0.1 1.5e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family EHN PF06441.12 EPE36539.1 - 3.1e-30 104.7 0.2 5.1e-30 104.0 0.2 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EPE36539.1 - 3.6e-12 46.5 0.0 7.1e-12 45.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPE36539.1 - 0.065 13.8 1.0 0.15 12.6 1.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Transp_cyt_pur PF02133.15 EPE36540.1 - 3.4e-31 108.5 27.8 4.7e-31 108.0 27.8 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FAD_binding_3 PF01494.19 EPE36542.1 - 8.8e-13 48.2 1.1 8.8e-10 38.3 1.3 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EPE36542.1 - 7.7e-05 22.1 0.0 0.0017 17.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE36542.1 - 0.00013 22.5 0.1 0.00027 21.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE36542.1 - 0.0047 15.7 0.1 0.0084 14.8 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EPE36542.1 - 0.0075 16.5 0.2 0.014 15.6 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPE36542.1 - 0.0099 15.5 0.1 0.12 11.9 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPE36542.1 - 0.075 12.1 2.8 0.049 12.7 0.8 1.6 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 EPE36542.1 - 0.17 10.7 0.1 5.8 5.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_4 PF07993.12 EPE36543.1 - 7.6e-22 77.7 0.0 1.3e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EPE36543.1 - 9.1e-07 28.6 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding PF00501.28 EPE36543.1 - 6.6e-05 21.7 0.0 0.016 13.8 0.1 2.2 2 0 0 2 2 2 2 AMP-binding enzyme BTB PF00651.31 EPE36544.1 - 3.8e-07 30.3 0.0 1.1e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain R2K_2 PF18299.1 EPE36544.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 Lactamase_B PF00753.27 EPE36545.1 - 4.6e-06 26.8 0.2 8.7e-06 25.9 0.2 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EPE36545.1 - 0.0058 16.2 0.0 0.0099 15.4 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain F-box-like PF12937.7 EPE36546.1 - 0.0033 17.3 0.3 0.019 14.8 0.1 2.3 2 0 0 2 2 2 1 F-box-like Gly_transf_sug PF04488.15 EPE36547.1 - 4.4e-11 43.3 0.1 1.1e-10 42.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EPE36547.1 - 0.011 15.1 0.6 0.028 13.8 0.6 1.7 1 1 0 1 1 1 0 Capsular polysaccharide synthesis protein DUF2610 PF11020.8 EPE36547.1 - 0.088 12.7 0.1 0.41 10.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2610) B12D PF06522.11 EPE36547.1 - 0.27 11.0 1.2 0.78 9.6 1.2 1.8 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit PI3K_1B_p101 PF10486.9 EPE36547.1 - 2.3 5.9 7.7 3.2 5.4 7.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Acyl_transf_3 PF01757.22 EPE36548.1 - 5.9e-33 114.3 37.5 7.4e-33 114.0 37.5 1.1 1 0 0 1 1 1 1 Acyltransferase family TPR_9 PF13371.6 EPE36550.1 - 0.0028 17.8 2.8 0.0052 16.9 1.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EPE36550.1 - 0.0053 17.2 7.3 6 7.5 1.9 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EPE36550.1 - 0.0067 16.1 1.7 0.11 12.2 2.3 2.7 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.6 EPE36550.1 - 0.22 12.4 5.8 1.1e+02 4.0 0.1 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EPE36550.1 - 4.8 7.6 5.8 11 6.5 0.6 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 EPE36551.1 - 2.2e-151 504.4 0.0 2.8e-151 504.0 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 EPE36551.1 - 2.8e-05 24.6 0.4 9.7 7.3 0.1 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EPE36551.1 - 0.00012 22.1 0.0 0.019 15.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EPE36551.1 - 0.00015 22.2 0.0 0.77 10.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPE36551.1 - 0.0015 18.5 0.1 0.5 10.6 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EPE36551.1 - 0.0081 16.3 0.0 1.1 9.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EPE36551.1 - 0.04 14.0 0.1 1.6 8.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TauE PF01925.19 EPE36553.1 - 0.0072 16.0 0.6 0.013 15.1 0.6 1.3 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE HET PF06985.11 EPE36553.1 - 0.011 16.1 1.9 0.026 14.9 1.9 1.6 1 1 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DUF1989 PF09347.10 EPE36553.1 - 0.13 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) DBI_PRT PF02277.17 EPE36553.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyltransferase Glyco_hydro_72 PF03198.14 EPE36554.1 - 1.2e-99 333.5 0.0 1.5e-99 333.2 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_3_C PF01915.22 EPE36556.1 - 5.7e-37 127.7 0.0 9.8e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE36556.1 - 6.6e-31 107.9 0.0 1.1e-30 107.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Colicin_D PF11429.8 EPE36559.1 - 5.4e-35 119.7 0.1 8e-35 119.1 0.1 1.3 1 0 0 1 1 1 1 Colicin D TUDOR PF00567.24 EPE36560.1 - 0.061 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Tudor domain Sas6_CC PF18594.1 EPE36561.1 - 4.1 7.3 5.0 29 4.6 0.0 3.1 4 0 0 4 4 4 0 Sas6/XLF/XRCC4 coiled-coil domain Pkinase PF00069.25 EPE36563.1 - 1e-51 175.9 0.1 1.1e-34 120.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE36563.1 - 4.2e-22 78.7 0.6 2.3e-20 73.0 0.2 3.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EPE36563.1 - 1.6e-05 24.3 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPE36563.1 - 0.0014 18.6 0.2 0.0053 16.7 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EPE36563.1 - 0.0018 17.1 0.0 0.0018 17.1 0.0 2.9 3 0 0 3 3 3 1 Fungal protein kinase Ribonuc_red_lgC PF02867.15 EPE36564.1 - 7e-189 628.7 0.0 9.8e-189 628.2 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EPE36564.1 - 2.5e-23 81.9 0.1 5.9e-23 80.7 0.1 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EPE36564.1 - 9.8e-16 58.1 0.0 2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain DGF-1_C PF11040.8 EPE36564.1 - 0.014 15.4 0.1 0.045 13.8 0.1 1.9 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus HET PF06985.11 EPE36566.1 - 1.9e-08 34.8 0.0 6.5e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MMR_HSR1 PF01926.23 EPE36566.1 - 1.2e-05 25.4 0.1 0.00018 21.6 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EPE36566.1 - 0.00023 20.6 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.13 EPE36566.1 - 0.00049 19.3 0.0 0.00098 18.3 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.6 EPE36566.1 - 0.00083 19.0 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AIG1 PF04548.16 EPE36566.1 - 0.0011 18.3 0.0 0.092 12.1 0.1 2.5 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 EPE36566.1 - 0.0017 18.3 0.1 0.0065 16.4 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EPE36566.1 - 0.0037 17.3 0.0 0.06 13.4 0.0 2.7 3 0 0 3 3 2 1 Dynamin family Septin PF00735.18 EPE36566.1 - 0.0044 16.3 0.1 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 Septin ABC_tran PF00005.27 EPE36566.1 - 0.0074 16.8 0.0 0.024 15.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter T2SSE PF00437.20 EPE36566.1 - 0.009 15.1 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.6 EPE36566.1 - 0.026 15.0 0.1 0.026 15.0 0.1 2.6 3 0 0 3 3 3 0 AAA domain dNK PF01712.19 EPE36566.1 - 0.028 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_10 PF12846.7 EPE36566.1 - 0.028 13.3 0.1 0.19 10.6 0.0 2.3 3 0 0 3 3 3 0 AAA-like domain DUF87 PF01935.17 EPE36566.1 - 0.058 13.5 0.1 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 EPE36566.1 - 0.075 13.4 0.1 0.53 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Sigma54_activat PF00158.26 EPE36566.1 - 0.097 12.4 0.0 0.26 11.0 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 EPE36566.1 - 0.16 12.3 0.0 0.41 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain 60KD_IMP PF02096.20 EPE36568.1 - 6.1e-15 55.5 0.0 1e-14 54.8 0.0 1.4 1 1 0 1 1 1 1 60Kd inner membrane protein ALG11_N PF15924.5 EPE36569.1 - 5.3e-84 281.4 0.0 7.5e-84 281.0 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EPE36569.1 - 4.1e-24 85.0 0.0 6e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EPE36569.1 - 8.1e-12 45.7 0.0 1.6e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EPE36569.1 - 0.0074 16.3 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 G_glu_transpept PF01019.21 EPE36570.1 - 1.6e-40 139.3 0.5 2e-40 139.0 0.5 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase G_glu_transpept PF01019.21 EPE36571.1 - 1.8e-116 389.9 0.0 2.2e-116 389.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1344 PF07076.11 EPE36571.1 - 0.092 12.7 0.4 5.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) COesterase PF00135.28 EPE36572.1 - 2.2e-75 254.5 0.0 2.9e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPE36572.1 - 9.7e-07 28.8 0.0 1.2e-05 25.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cas_Csx8 PF09657.10 EPE36573.1 - 0.25 10.3 0.0 0.32 9.9 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein Csx8 (Cas_Csx8) Fungal_trans_2 PF11951.8 EPE36574.1 - 2.7e-06 26.5 0.6 4.3e-06 25.8 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE36574.1 - 6.1e-05 23.1 10.9 0.00011 22.2 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cas9_Topo PF17894.1 EPE36574.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 Ank_2 PF12796.7 EPE36575.1 - 1.3e-31 109.0 10.8 2.9e-06 27.8 0.1 6.1 5 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE36575.1 - 1.9e-20 72.9 9.4 3.6e-06 27.4 0.1 7.9 7 2 3 10 10 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE36575.1 - 1.2e-19 68.4 10.1 0.054 14.1 0.0 10.8 10 0 0 10 10 10 5 Ankyrin repeat Ank PF00023.30 EPE36575.1 - 5.8e-12 45.5 14.5 0.083 13.4 0.0 9.5 10 0 0 10 10 10 3 Ankyrin repeat Ank_5 PF13857.6 EPE36575.1 - 7.2e-11 42.1 7.9 0.072 13.4 0.1 7.0 6 1 1 7 7 7 4 Ankyrin repeats (many copies) NACHT PF05729.12 EPE36575.1 - 2.6e-08 34.0 0.0 1.1e-07 32.0 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EPE36575.1 - 3.8e-05 24.0 0.1 0.00021 21.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPE36575.1 - 0.00028 21.3 0.1 0.00083 19.8 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT_N PF17100.5 EPE36575.1 - 0.004 17.0 0.1 0.0079 16.1 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase AAA_19 PF13245.6 EPE36575.1 - 0.027 14.8 0.0 0.19 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 EPE36575.1 - 0.035 13.3 1.9 0.1 11.8 0.1 2.2 2 0 0 2 2 2 0 KAP family P-loop domain PIF1 PF05970.14 EPE36575.1 - 0.15 11.2 0.1 0.47 9.6 0.0 1.8 3 0 0 3 3 3 0 PIF1-like helicase Carn_acyltransf PF00755.20 EPE36576.1 - 2.7e-206 686.7 0.0 5.7e-206 685.7 0.0 1.5 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase SPT2 PF08243.11 EPE36577.1 - 0.00022 21.7 29.2 0.00022 21.7 29.2 2.8 2 1 0 2 2 2 1 SPT2 chromatin protein NOA36 PF06524.12 EPE36577.1 - 0.47 9.7 5.6 0.86 8.9 5.6 1.4 1 0 0 1 1 1 0 NOA36 protein Connexin40_C PF16791.5 EPE36577.1 - 0.8 11.0 6.5 4.7 8.5 0.1 3.0 3 0 0 3 3 3 0 Connexin 40 C-terminal domain FAM176 PF14851.6 EPE36577.1 - 8.1 6.1 12.2 21 4.7 12.2 1.8 1 0 0 1 1 1 0 FAM176 family Glyco_hydro_cc PF11790.8 EPE36578.1 - 4.1e-60 203.3 0.2 5.9e-60 202.8 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core HET PF06985.11 EPE36579.1 - 0.043 14.2 0.3 0.081 13.3 0.3 1.5 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) SopA PF13981.6 EPE36581.1 - 0.032 14.6 0.0 0.057 13.9 0.0 1.3 1 0 0 1 1 1 0 SopA-like central domain Chromo PF00385.24 EPE36582.1 - 7.3e-08 32.2 1.3 1.2e-07 31.5 1.3 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tra_M PF05261.11 EPE36582.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 TraM protein, DNA-binding SIL1 PF16782.5 EPE36583.1 - 2.2e-14 53.4 0.0 2.9e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Methyltransf_11 PF08241.12 EPE36584.1 - 6.3e-12 46.0 0.0 1.3e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE36584.1 - 5e-05 23.9 0.0 0.0001 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE36584.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EPE36584.1 - 0.018 15.8 0.0 0.034 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EPE36584.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 EPE36586.1 - 1.3e-52 178.8 0.0 1.7e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EPE36586.1 - 1.1e-19 70.7 0.0 3.1e-19 69.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EPE36586.1 - 3.3e-16 59.6 1.3 1.7e-15 57.3 1.2 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE36586.1 - 1.2e-08 34.6 0.0 1.5e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE36586.1 - 1.5e-05 25.1 0.2 0.13 12.6 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 EPE36586.1 - 0.083 13.2 0.1 1.7 8.9 0.2 2.3 2 0 0 2 2 2 0 TrkA-N domain HECT_2 PF09814.9 EPE36587.1 - 5e-103 344.9 2.9 5.9e-103 344.6 2.9 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 EPE36587.1 - 0.03 14.5 1.1 0.13 12.5 1.1 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly FAD_binding_3 PF01494.19 EPE36588.1 - 6.7e-21 74.9 0.0 1.5e-09 37.5 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EPE36588.1 - 4.6e-06 26.8 0.0 9.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE36588.1 - 3.9e-05 23.0 0.0 0.00028 20.2 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE36588.1 - 8.1e-05 21.8 0.0 0.028 13.5 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 EPE36588.1 - 0.00054 19.7 0.0 0.00086 19.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPE36588.1 - 0.0013 18.0 0.0 0.009 15.3 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE36588.1 - 0.0077 16.8 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EPE36588.1 - 0.009 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.24 EPE36588.1 - 0.012 14.9 0.0 0.074 12.3 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EPE36588.1 - 0.043 12.9 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EPE36588.1 - 0.06 13.3 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding SE PF08491.10 EPE36588.1 - 0.061 12.4 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Squalene epoxidase 3HCDH_N PF02737.18 EPE36588.1 - 0.099 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EPE36588.1 - 0.15 11.4 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EPE36588.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EPE36588.1 - 0.18 12.1 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Questin_oxidase PF14027.6 EPE36589.1 - 1.7e-94 317.1 0.2 2.2e-94 316.8 0.2 1.1 1 0 0 1 1 1 1 Questin oxidase-like Rad17 PF03215.15 EPE36590.1 - 3.4e-24 85.8 0.0 7.7e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 EPE36590.1 - 0.041 13.9 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HET PF06985.11 EPE36591.1 - 1.7e-24 86.9 0.0 3.1e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C3HC4 PF00097.25 EPE36592.1 - 3.4e-12 46.0 8.7 5.6e-12 45.3 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE36592.1 - 1.9e-11 43.8 5.1 1.9e-11 43.8 5.1 1.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EPE36592.1 - 8.3e-11 41.5 10.4 1.9e-10 40.4 10.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPE36592.1 - 1.3e-10 41.4 9.6 2.1e-10 40.8 9.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EPE36592.1 - 2e-10 40.4 5.1 2.8e-10 39.9 5.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPE36592.1 - 4.1e-07 30.2 5.3 8.2e-07 29.2 5.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EPE36592.1 - 4.6e-07 29.7 7.2 7.3e-07 29.0 7.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EPE36592.1 - 1e-06 28.5 7.6 5.8e-05 22.9 7.6 2.3 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EPE36592.1 - 2.1e-06 27.8 7.3 4e-06 26.9 7.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EPE36592.1 - 4.1e-06 26.5 6.4 7.3e-06 25.7 6.4 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 EPE36592.1 - 0.00051 20.0 3.8 0.0013 18.8 3.8 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger NOA36 PF06524.12 EPE36592.1 - 0.0018 17.7 12.5 0.0025 17.2 12.5 1.3 1 0 0 1 1 1 1 NOA36 protein zf-RING_10 PF16685.5 EPE36592.1 - 0.0035 17.4 4.4 0.0071 16.5 4.4 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_11 PF17123.5 EPE36592.1 - 0.011 15.5 3.7 0.011 15.5 3.7 1.7 2 0 0 2 2 1 0 RING-like zinc finger zf-MIZ PF02891.20 EPE36592.1 - 0.014 15.2 6.6 0.021 14.6 6.6 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger UBZ_FAAP20 PF15750.5 EPE36592.1 - 0.088 12.8 1.0 2.2 8.3 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Zn-C2H2_12 PF18112.1 EPE36592.1 - 0.11 13.0 0.2 0.11 13.0 0.2 2.9 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain zinc-ribbons_6 PF07191.12 EPE36592.1 - 0.13 12.2 3.6 0.25 11.3 3.6 1.5 1 0 0 1 1 1 0 zinc-ribbons DUF1644 PF07800.12 EPE36592.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1644) zf-RING_6 PF14835.6 EPE36592.1 - 0.18 11.7 2.2 0.39 10.6 2.2 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2_9 PF16293.5 EPE36592.1 - 0.22 11.4 3.5 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn_ribbon_17 PF17120.5 EPE36592.1 - 0.39 10.4 5.5 1.3 8.7 5.5 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type TFB6 PF17110.5 EPE36592.1 - 0.62 9.8 5.8 0.8 9.4 5.8 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH ALMT PF11744.8 EPE36592.1 - 0.73 8.6 2.6 0.85 8.4 2.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter zinc_ribbon_9 PF14369.6 EPE36592.1 - 0.75 10.1 6.3 10 6.5 0.6 2.8 2 0 0 2 2 2 0 zinc-ribbon Cwf_Cwc_15 PF04889.12 EPE36592.1 - 0.76 9.5 14.8 0.98 9.1 14.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Baculo_IE-1 PF05290.11 EPE36592.1 - 0.78 9.7 4.0 1.1 9.3 3.5 1.4 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) BUD22 PF09073.10 EPE36592.1 - 0.86 8.9 14.7 1 8.6 14.7 1.1 1 0 0 1 1 1 0 BUD22 zf-RING_4 PF14570.6 EPE36592.1 - 1.4 8.8 13.0 0.56 10.0 2.3 2.8 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain Nop14 PF04147.12 EPE36592.1 - 1.6 6.9 14.9 1.7 6.7 14.9 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 EPE36592.1 - 2 8.4 13.2 4.5 7.3 13.2 1.6 1 1 0 1 1 1 0 RXT2-like, N-terminal zf-C2H2_4 PF13894.6 EPE36592.1 - 2.3 9.3 7.9 3 8.9 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger DNA_pol_phi PF04931.13 EPE36592.1 - 5.3 5.0 22.1 6.2 4.8 22.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EPE36592.1 - 9 4.5 12.4 9.9 4.3 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2 PF00096.26 EPE36592.1 - 9 7.0 8.5 3.9 8.1 0.1 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Rad51 PF08423.11 EPE36593.1 - 1.2e-44 152.5 0.0 1.7e-43 148.7 0.0 2.0 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 EPE36593.1 - 1e-06 28.5 0.2 0.00029 20.4 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein ATPase PF06745.13 EPE36593.1 - 3.4e-05 23.3 0.1 0.00014 21.3 0.1 2.0 2 1 0 2 2 2 1 KaiC AAA_25 PF13481.6 EPE36593.1 - 0.00023 20.8 0.1 0.00093 18.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain DnaB_C PF03796.15 EPE36593.1 - 0.0023 17.3 0.1 0.098 12.0 0.1 2.2 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 EPE36593.1 - 0.043 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PAN_1 PF00024.26 EPE36595.1 - 9.1e-05 22.3 0.3 0.00019 21.3 0.3 1.4 1 0 0 1 1 1 1 PAN domain Fringe PF02434.16 EPE36595.1 - 0.011 15.3 0.8 0.14 11.6 0.8 2.1 1 1 0 1 1 1 0 Fringe-like PAN_3 PF08277.12 EPE36595.1 - 0.043 13.6 0.8 0.078 12.8 0.8 1.4 1 0 0 1 1 1 0 PAN-like domain Herpes_UL69 PF05459.12 EPE36596.1 - 0.056 12.8 0.0 0.066 12.6 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus transcriptional regulator family zf-C2H2 PF00096.26 EPE36597.1 - 0.0062 16.9 2.1 0.0062 16.9 2.1 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type ODAPH PF15848.5 EPE36598.1 - 0.32 11.5 3.5 0.48 10.9 0.0 2.5 2 1 1 3 3 3 0 Odontogenesis associated phosphoprotein adh_short PF00106.25 EPE36599.1 - 1.4e-25 89.9 0.0 1.9e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE36599.1 - 5.3e-15 55.6 0.0 6.7e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EPE36599.1 - 0.0043 16.5 0.0 0.084 12.2 0.0 2.0 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EPE36599.1 - 0.0086 16.0 0.1 1.9 8.4 0.0 2.2 2 0 0 2 2 2 2 KR domain DRMBL PF07522.14 EPE36600.1 - 6.7e-36 122.8 0.1 1.2e-35 122.0 0.1 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EPE36600.1 - 1.6e-06 27.8 0.0 3.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain LSM PF01423.22 EPE36601.1 - 1.5e-17 63.0 0.5 2.5e-17 62.3 0.5 1.4 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EPE36601.1 - 0.019 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Hfq protein SM-ATX PF14438.6 EPE36601.1 - 0.05 13.7 0.0 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain SnoaL PF07366.12 EPE36602.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EPE36602.1 - 0.023 15.4 0.1 0.047 14.3 0.1 1.4 1 0 0 1 1 1 0 SnoaL-like domain Ank_4 PF13637.6 EPE36603.1 - 3.9e-19 68.7 0.0 2.5e-10 40.7 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE36603.1 - 9.6e-19 67.8 0.1 7.6e-08 32.8 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPE36603.1 - 1.3e-17 63.6 0.1 1.1e-06 28.8 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EPE36603.1 - 3.5e-14 52.5 0.3 0.0019 18.6 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EPE36603.1 - 4.2e-11 42.1 0.0 0.072 13.7 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat CorA PF01544.18 EPE36603.1 - 0.00027 20.3 8.6 0.00027 20.3 8.6 2.7 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Yip1 PF04893.17 EPE36603.1 - 8.2 6.1 12.1 18 5.0 11.4 1.5 1 1 0 1 1 1 0 Yip1 domain DUF418 PF04235.12 EPE36603.1 - 9.9 6.1 8.1 14 5.5 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF418) Fig1 PF12351.8 EPE36604.1 - 8.3e-51 172.6 0.7 8.3e-51 172.6 0.7 1.9 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 3Beta_HSD PF01073.19 EPE36605.1 - 1.5e-05 24.2 0.1 1.8e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EPE36605.1 - 3.6e-05 23.7 0.0 4.6e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EPE36605.1 - 0.011 15.0 0.0 0.67 9.1 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein HET PF06985.11 EPE36608.1 - 5e-16 59.4 0.0 6.5e-15 55.7 0.0 2.8 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) zf-H2C2_2 PF13465.6 EPE36608.1 - 0.016 15.6 11.2 0.067 13.7 0.5 4.1 4 0 0 4 4 4 0 Zinc-finger double domain zf-BED PF02892.15 EPE36608.1 - 0.028 14.4 1.3 7.2 6.7 0.1 2.8 2 0 0 2 2 2 0 BED zinc finger DUF724 PF05266.14 EPE36608.1 - 0.39 10.5 8.7 0.86 9.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF724) zf-C2H2 PF00096.26 EPE36608.1 - 10 6.8 16.9 14 6.4 0.2 4.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type Peptidase_S8 PF00082.22 EPE36610.1 - 6.3e-05 22.4 2.1 0.068 12.4 0.5 3.4 3 1 0 3 3 3 2 Subtilase family Ribosomal_S8e PF01201.22 EPE36611.1 - 1.9e-48 164.1 1.1 2.8e-48 163.6 0.5 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e RIBIOP_C PF04950.12 EPE36611.1 - 0.35 10.3 4.5 0.76 9.1 4.5 1.6 1 1 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Ribosomal_L21p PF00829.21 EPE36612.1 - 4.4e-12 46.1 0.0 6.1e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF3433 PF11915.8 EPE36613.1 - 8.1e-31 106.3 20.0 6e-18 65.1 1.5 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF2417 PF10329.9 EPE36613.1 - 0.12 11.8 1.9 2.6 7.4 1.0 3.0 3 0 0 3 3 3 0 Region of unknown function (DUF2417) AA_permease PF00324.21 EPE36614.1 - 1.1e-99 334.2 48.3 1.4e-99 333.9 48.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE36614.1 - 9.1e-31 107.1 52.1 1.3e-30 106.6 52.1 1.2 1 0 0 1 1 1 1 Amino acid permease Synaptobrevin PF00957.21 EPE36614.1 - 1.6 8.6 0.0 1.6 8.6 0.0 4.3 6 0 0 6 6 6 0 Synaptobrevin RF-1 PF00472.20 EPE36615.1 - 0.025 14.5 0.3 0.035 14.1 0.3 1.3 1 0 0 1 1 1 0 RF-1 domain Peptidase_M48 PF01435.18 EPE36616.1 - 1.8e-06 27.8 0.0 2.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Ndc1_Nup PF09531.10 EPE36617.1 - 0.13 10.9 0.6 0.15 10.7 0.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Miff PF05644.11 EPE36618.1 - 0.78 9.3 8.7 1.5 8.4 8.7 1.5 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Asp PF00026.23 EPE36619.1 - 3.1e-14 53.1 0.1 5.1e-14 52.4 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Podoplanin PF05808.11 EPE36619.1 - 0.011 15.9 0.2 0.029 14.5 0.2 1.7 1 0 0 1 1 1 0 Podoplanin Gram_pos_anchor PF00746.21 EPE36619.1 - 0.021 14.7 1.2 0.045 13.7 1.2 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif VSP PF03302.13 EPE36619.1 - 0.092 11.6 0.6 0.12 11.2 0.6 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein WW_FCH_linker PF16623.5 EPE36619.1 - 0.16 12.7 0.0 0.16 12.7 0.0 2.8 3 0 0 3 3 3 0 Unstructured linker region between on GAS7 protein Vanabin-2 PF11437.8 EPE36620.1 - 0.47 10.6 18.4 9.6 6.4 11.8 2.9 2 1 0 2 2 2 0 Vanadium-binding protein 2 Pkinase PF00069.25 EPE36621.1 - 2.1e-44 151.9 0.0 3.4e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE36621.1 - 8.3e-18 64.6 0.0 1.4e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPE36621.1 - 0.0022 17.9 0.1 1.9 8.4 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EPE36621.1 - 0.011 15.3 0.2 0.025 14.2 0.2 1.5 1 0 0 1 1 1 0 RIO1 family Lipase_GDSL_2 PF13472.6 EPE36622.1 - 6.2e-13 49.5 0.0 7.7e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPE36622.1 - 3.9e-06 27.0 0.0 9.5e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PCI PF01399.27 EPE36623.1 - 5.3e-12 46.2 0.0 2.3e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 EPE36623.1 - 4.4e-05 23.2 0.1 0.00011 22.0 0.1 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PI-PLC-X PF00388.19 EPE36624.1 - 1.3e-48 164.3 0.0 2e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EPE36624.1 - 1.4e-38 131.8 0.0 2.2e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EPE36624.1 - 0.00054 20.2 0.1 0.0021 18.3 0.0 2.1 2 0 0 2 2 2 1 C2 domain TFIIF_beta_N PF17683.1 EPE36625.1 - 2.3e-38 131.9 0.6 3.6e-38 131.3 0.6 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 EPE36625.1 - 7.4e-30 102.9 0.1 1.4e-29 102.0 0.1 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain zf-CCCH PF00642.24 EPE36626.1 - 2e-14 53.1 28.2 9.2e-06 25.4 0.7 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EPE36626.1 - 3.5e-10 39.6 28.6 0.00051 20.0 1.8 6.1 5 1 0 5 5 5 4 Zinc finger domain zf-CCCH_4 PF18044.1 EPE36626.1 - 1.2e-07 31.4 20.3 0.0024 17.6 1.1 4.2 4 0 0 4 4 4 3 CCCH-type zinc finger Torus PF16131.5 EPE36626.1 - 0.00058 20.5 28.6 0.067 13.9 0.8 4.9 2 1 3 5 5 5 3 Torus domain DUF2513 PF10711.9 EPE36626.1 - 0.016 15.5 0.1 0.03 14.6 0.1 1.4 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) zf-CCCH_3 PF15663.5 EPE36626.1 - 0.066 13.4 18.7 0.051 13.8 1.4 3.7 1 1 2 3 3 3 0 Zinc-finger containing family DUF4685 PF15737.5 EPE36626.1 - 0.57 10.6 0.0 0.57 10.6 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4685) zf-C3H1 PF10650.9 EPE36626.1 - 5.9 6.7 8.4 14 5.6 0.0 3.6 4 0 0 4 4 4 0 Putative zinc-finger domain zf-CCCH_2 PF14608.6 EPE36626.1 - 9.7 6.8 35.3 0.1 13.1 4.6 4.8 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger bZIP_1 PF00170.21 EPE36627.1 - 8.9e-08 32.1 7.0 8.9e-08 32.1 7.0 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 EPE36627.1 - 8e-07 29.5 11.8 8e-07 29.5 11.8 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 EPE36627.1 - 8.5e-06 25.8 9.5 8.5e-06 25.8 9.5 2.0 2 0 0 2 2 2 1 Basic region leucine zipper AAA_23 PF13476.6 EPE36627.1 - 0.073 13.6 6.8 0.15 12.6 6.8 1.5 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.8 EPE36627.1 - 1.1 8.6 14.1 2.8 7.2 14.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 EPE36627.1 - 2.4 8.2 18.3 5 7.2 18.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sel1 PF08238.12 EPE36628.1 - 1.3e-13 51.1 5.8 0.00019 22.0 0.0 4.0 4 0 0 4 4 4 3 Sel1 repeat CBF PF03914.17 EPE36629.1 - 1.8e-37 129.0 0.6 6.7e-37 127.1 0.2 2.1 3 0 0 3 3 3 1 CBF/Mak21 family DUF3201 PF11447.8 EPE36629.1 - 0.063 12.8 2.6 1.4 8.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3201) Mt_ATP-synt_B PF05405.14 EPE36630.1 - 1.5e-55 187.3 7.0 1.9e-55 186.9 7.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Peptidase_C10 PF01640.17 EPE36630.1 - 0.17 12.2 0.4 0.47 10.7 0.1 1.6 1 1 0 2 2 2 0 Peptidase C10 family DUF3410 PF11890.8 EPE36631.1 - 0.13 12.1 2.4 0.1 12.4 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) DAO PF01266.24 EPE36633.1 - 1.1e-42 146.9 0.0 1.2e-42 146.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EPE36633.1 - 2.8e-07 30.7 0.2 8.7e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EPE36633.1 - 8.3e-06 25.3 0.7 0.014 14.7 0.1 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EPE36633.1 - 6.5e-05 22.4 0.0 0.0073 15.6 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPE36633.1 - 8.8e-05 22.7 0.1 0.00025 21.2 0.1 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPE36633.1 - 0.00011 21.5 1.1 0.29 10.3 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPE36633.1 - 0.00015 20.6 0.2 0.0092 14.7 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EPE36633.1 - 0.0018 17.6 0.0 0.0035 16.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 EPE36633.1 - 0.0059 15.8 0.0 0.46 9.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EPE36633.1 - 0.023 13.8 0.6 0.57 9.2 0.0 2.6 2 1 1 3 3 3 0 FAD binding domain MCRA PF06100.11 EPE36633.1 - 0.026 13.3 0.2 0.44 9.3 0.1 2.1 2 0 0 2 2 2 0 MCRA family Pyr_redox PF00070.27 EPE36633.1 - 0.059 13.9 0.9 13 6.4 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M28 PF04389.17 EPE36634.1 - 5.7e-40 137.1 0.2 7.8e-40 136.7 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EPE36634.1 - 5.8e-11 42.3 0.4 1.8e-10 40.7 0.4 1.9 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EPE36634.1 - 0.00026 20.8 0.1 0.00055 19.7 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1664 PF07889.12 EPE36635.1 - 0.63 10.1 5.8 0.43 10.6 3.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) F-box-like PF12937.7 EPE36636.1 - 0.03 14.2 0.0 0.03 14.2 0.0 2.5 3 0 0 3 3 3 0 F-box-like zf-CCCH_4 PF18044.1 EPE36636.1 - 1.4 8.8 4.5 0.24 11.2 0.2 2.0 2 0 0 2 2 2 0 CCCH-type zinc finger HTH_Tnp_Tc3_2 PF01498.18 EPE36637.1 - 1.2e-18 67.1 0.9 2.7e-18 66.0 0.9 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.6 EPE36637.1 - 8.9e-15 54.7 0.8 8.9e-15 54.7 0.8 2.0 2 1 0 2 2 2 1 DDE superfamily endonuclease HTH_33 PF13592.6 EPE36637.1 - 0.00013 21.5 0.1 0.00059 19.4 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.6 EPE36637.1 - 0.027 15.1 2.1 0.29 11.8 0.2 2.6 2 0 0 2 2 2 0 Homeodomain-like domain RWP-RK PF02042.15 EPE36637.1 - 0.029 14.4 0.7 0.029 14.4 0.7 2.0 2 0 0 2 2 2 0 RWP-RK domain HTH_24 PF13412.6 EPE36637.1 - 0.18 11.4 0.0 0.51 9.9 0.0 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Amidohydro_1 PF01979.20 EPE36639.1 - 2.2e-24 86.4 0.0 3.2e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPE36639.1 - 2e-19 70.4 0.0 2.6e-10 40.4 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Asp_Glu_race PF01177.22 EPE36640.1 - 1.2e-08 35.1 0.1 2.2e-08 34.2 0.1 1.5 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase CN_hydrolase PF00795.22 EPE36641.1 - 2.3e-44 151.7 0.0 4.5e-44 150.7 0.0 1.4 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.18 EPE36642.1 - 3.9e-23 81.8 0.2 5.4e-23 81.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE36642.1 - 0.00017 21.6 9.2 0.00038 20.5 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_tranf_2_4 PF13704.6 EPE36643.1 - 4.7e-09 36.6 0.5 8.1e-09 35.9 0.5 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 EPE36643.1 - 7.7e-09 35.6 0.8 1.4e-08 34.7 0.6 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 92 Octopine_DH PF02317.17 EPE36643.1 - 0.091 12.8 0.4 9.5 6.3 0.1 2.3 1 1 1 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Glycos_transf_2 PF00535.26 EPE36643.1 - 0.15 11.8 0.0 0.35 10.7 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 YihI PF04220.12 EPE36643.1 - 0.17 11.6 0.1 0.28 10.9 0.1 1.2 1 0 0 1 1 1 0 Der GTPase activator (YihI) GFO_IDH_MocA PF01408.22 EPE36645.1 - 5.6e-17 62.7 0.1 8.5e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold UCH PF00443.29 EPE36646.1 - 2.6e-26 92.7 0.0 3.8e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPE36646.1 - 1.1e-16 61.4 2.9 4.1e-16 59.5 0.6 2.0 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Tim54 PF11711.8 EPE36647.1 - 1.6e-138 461.6 0.1 2e-138 461.3 0.1 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.8 EPE36648.1 - 2.2e-198 660.4 27.0 1.9e-196 654.0 20.2 2.4 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 EPE36648.1 - 6.3e-17 61.8 24.7 0.0071 16.8 0.0 8.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 EPE36648.1 - 2.2e-16 59.1 13.6 0.0084 16.9 0.1 10.0 6 3 4 10 10 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 EPE36648.1 - 5.3e-15 54.2 36.7 0.0013 18.7 0.1 10.6 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 EPE36648.1 - 2.1e-14 53.9 26.3 0.0021 18.7 0.3 8.9 7 1 1 9 9 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EPE36648.1 - 1.3e-12 47.7 17.9 1.4e-05 25.3 1.1 5.6 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EPE36648.1 - 4.2e-11 42.2 30.7 6.4e-05 22.6 0.1 8.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPE36648.1 - 5.6e-11 42.0 5.5 0.012 15.9 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 EPE36648.1 - 1.6e-08 34.6 8.8 0.0011 19.0 1.7 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EPE36648.1 - 3.8e-08 32.9 12.6 0.00014 21.4 0.1 6.5 8 0 0 8 8 8 2 TPR repeat TPR_12 PF13424.6 EPE36648.1 - 3.7e-06 27.1 23.3 0.27 11.5 2.9 8.1 7 2 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EPE36648.1 - 4.3e-06 26.3 5.8 0.051 12.9 0.1 4.0 2 2 2 4 4 4 3 MalT-like TPR region TPR_8 PF13181.6 EPE36648.1 - 4.6e-06 26.4 28.1 0.0043 17.2 0.0 7.8 10 0 0 10 10 7 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EPE36648.1 - 7e-05 22.8 5.6 0.68 10.1 0.1 4.6 5 0 0 5 5 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EPE36648.1 - 0.0082 16.7 21.6 9.1 7.2 0.0 8.9 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF913 PF06025.12 EPE36648.1 - 0.069 12.1 0.4 0.14 11.1 0.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TPR_7 PF13176.6 EPE36648.1 - 0.31 11.2 19.7 12 6.1 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_4 PF07721.14 EPE36648.1 - 0.69 10.7 7.7 20 6.2 0.1 5.0 6 0 0 6 6 3 0 Tetratricopeptide repeat BTAD PF03704.17 EPE36648.1 - 0.97 9.9 6.0 10 6.5 0.3 3.2 2 1 0 2 2 2 0 Bacterial transcriptional activator domain Cid2 PF09774.9 EPE36649.1 - 2.7e-56 190.4 0.1 3.2e-56 190.2 0.1 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Mito_carr PF00153.27 EPE36650.1 - 1.7e-42 143.3 4.1 2.6e-16 59.3 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein JAB PF01398.21 EPE36652.1 - 3.6e-07 30.2 0.1 7.3e-06 26.0 0.1 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AdoHcyase PF05221.17 EPE36653.1 - 6.4e-127 422.8 0.0 4e-72 242.9 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EPE36653.1 - 3.1e-83 277.7 1.7 4.6e-83 277.1 1.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EPE36653.1 - 1e-07 31.5 0.2 2e-07 30.5 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EPE36653.1 - 0.0031 17.1 0.5 0.0056 16.3 0.5 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 EPE36653.1 - 0.0045 16.7 0.1 0.0079 15.9 0.1 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ATG11 PF10377.9 EPE36654.1 - 8.2e-44 148.8 0.2 8.2e-44 148.8 0.2 5.0 7 0 0 7 7 7 1 Autophagy-related protein 11 Spc7 PF08317.11 EPE36654.1 - 0.0012 17.8 15.7 0.0012 17.8 15.7 5.8 5 1 1 6 6 6 2 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 EPE36654.1 - 0.0085 16.1 0.3 0.0085 16.1 0.3 5.5 5 1 1 6 6 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus NuA4 PF09340.10 EPE36654.1 - 0.034 14.0 0.7 0.18 11.7 0.0 2.8 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Nab2 PF11517.8 EPE36654.1 - 0.061 13.6 0.1 0.29 11.5 0.1 2.2 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) HSBP1 PF06825.12 EPE36654.1 - 1.4 8.8 9.9 3.4 7.6 0.2 4.7 4 0 0 4 4 4 0 Heat shock factor binding protein 1 APG17 PF04108.12 EPE36654.1 - 3.4 6.7 63.9 0.019 14.1 5.2 6.6 3 3 1 4 4 4 0 Autophagy protein Apg17 SET PF00856.28 EPE36655.1 - 8.1e-14 52.3 0.0 1.2e-13 51.8 0.0 1.2 1 0 0 1 1 1 1 SET domain Ank_2 PF12796.7 EPE36656.1 - 4e-94 309.3 11.8 1.3e-17 64.1 0.0 10.3 3 2 7 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE36656.1 - 4.4e-92 301.4 16.5 1e-11 45.1 0.1 15.1 4 3 11 15 15 15 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE36656.1 - 6.4e-76 241.2 10.1 2.7e-07 30.3 0.0 17.7 17 0 0 17 17 17 13 Ankyrin repeat Ank PF00023.30 EPE36656.1 - 3e-75 245.6 22.3 5.3e-08 33.0 0.0 17.3 18 0 0 18 18 17 12 Ankyrin repeat Ank_5 PF13857.6 EPE36656.1 - 3.9e-63 208.7 25.9 1.6e-10 41.1 0.1 10.6 6 3 5 11 11 11 11 Ankyrin repeats (many copies) Goodbye PF17109.5 EPE36656.1 - 2.2e-17 63.6 0.0 5.8e-17 62.3 0.0 1.8 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 EPE36656.1 - 6.1e-06 26.2 0.0 1.8e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EPE36656.1 - 0.01 16.1 0.0 0.046 14.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain Ribosomal_S6 PF01250.17 EPE36656.1 - 0.016 15.5 0.5 13 6.2 0.0 4.7 5 1 1 6 6 6 0 Ribosomal protein S6 NB-ARC PF00931.22 EPE36656.1 - 0.027 13.6 0.0 0.06 12.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain VWA_3_C PF18571.1 EPE36656.1 - 0.12 12.3 0.6 97 3.0 0.1 4.7 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain CENP-H PF05837.12 EPE36657.1 - 1.4e-33 115.6 5.9 1.4e-33 115.6 5.9 1.9 2 1 0 2 2 2 1 Centromere protein H (CENP-H) DUF874 PF05917.11 EPE36657.1 - 0.0063 15.6 2.2 0.0082 15.2 2.2 1.1 1 0 0 1 1 1 1 Helicobacter pylori protein of unknown function (DUF874) Cas6 PF09559.10 EPE36657.1 - 0.02 14.8 0.2 0.034 14.1 0.2 1.3 1 0 0 1 1 1 0 Cas6 Crispr MRP-S28 PF10213.9 EPE36657.1 - 0.072 13.5 1.5 0.13 12.7 1.5 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein KIP1 PF07765.12 EPE36657.1 - 0.31 11.2 4.7 1 9.5 0.3 2.6 1 1 1 2 2 2 0 KIP1-like protein Mu-like_Pro PF10123.9 EPE36657.1 - 0.49 9.9 11.4 2.6 7.5 11.4 1.9 1 1 0 1 1 1 0 Mu-like prophage I protein Muted PF14942.6 EPE36657.1 - 0.61 10.4 7.0 0.4 11.0 4.3 2.0 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein UPF0515 PF15135.6 EPE36657.1 - 6.3 6.1 6.2 13 5.1 3.9 2.0 1 1 1 2 2 2 0 Uncharacterised protein UPF0515 HMG_box PF00505.19 EPE36658.1 - 6.1e-24 84.2 0.4 6.1e-24 84.2 0.4 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EPE36658.1 - 4.1e-18 65.7 0.6 7.8e-18 64.8 0.6 1.4 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EPE36658.1 - 0.002 18.7 0.0 0.002 18.7 0.0 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 CHDNT PF08073.12 EPE36658.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain RNB PF00773.19 EPE36660.1 - 1.5e-98 330.1 0.7 2.6e-98 329.4 0.7 1.4 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 EPE36660.1 - 4e-28 98.0 0.3 1e-27 96.7 0.3 1.7 1 1 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EPE36660.1 - 4.7e-28 97.0 0.3 4.7e-28 97.0 0.3 2.0 2 0 0 2 2 2 1 S1 domain OB_Dis3 PF17849.1 EPE36660.1 - 5e-21 74.5 0.0 1.5e-20 73.0 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 EPE36660.1 - 1.6e-10 41.0 4.9 5.2e-07 29.7 0.0 3.6 2 1 1 3 3 3 2 Cold shock domain PIN_4 PF13638.6 EPE36660.1 - 3.7e-10 40.2 0.1 1.3e-09 38.4 0.1 2.0 1 0 0 1 1 1 1 PIN domain Dis3l2_C_term PF17877.1 EPE36660.1 - 0.0057 17.0 0.1 0.025 14.9 0.1 2.1 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal HET PF06985.11 EPE36661.1 - 1.6e-24 86.9 0.1 5.2e-24 85.3 0.1 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) GN3L_Grn1 PF08701.11 EPE36662.1 - 9.5e-23 80.1 13.9 9.5e-23 80.1 13.9 1.8 2 0 0 2 2 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EPE36662.1 - 2.8e-17 62.8 0.1 3.7e-13 49.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPE36662.1 - 1.3e-07 31.7 0.2 1.5e-06 28.2 0.2 2.2 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EPE36662.1 - 4.3e-07 29.6 0.1 7.1e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EPE36662.1 - 4.1e-05 23.7 4.3 0.28 11.2 0.7 3.9 3 1 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 EPE36662.1 - 0.00012 21.7 0.0 0.028 13.9 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EPE36662.1 - 0.0029 16.7 0.1 0.0029 16.7 0.1 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 EPE36662.1 - 0.039 13.4 0.1 0.35 10.3 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 EPE36662.1 - 0.067 13.7 0.0 0.22 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EPE36662.1 - 0.12 11.9 0.1 0.85 9.2 0.0 2.2 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Nuc_deoxyri_tr2 PF15891.5 EPE36662.1 - 0.34 11.2 1.4 1.7 9.0 0.0 2.7 2 1 1 3 3 3 0 Nucleoside 2-deoxyribosyltransferase like AAA_16 PF13191.6 EPE36662.1 - 0.49 10.8 0.0 0.49 10.8 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain Enolase_N PF03952.16 EPE36662.1 - 0.84 9.8 4.0 6.5 6.9 0.0 3.0 3 0 0 3 3 3 0 Enolase, N-terminal domain HAD_2 PF13419.6 EPE36663.1 - 2.6e-16 60.2 0.0 3.8e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPE36663.1 - 4.7e-08 33.6 0.0 7.4e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPE36663.1 - 5.5e-07 29.6 0.0 9.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like GHL6 PF14871.6 EPE36663.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 TIP49 PF06068.13 EPE36664.1 - 7.7e-167 554.9 0.1 9.6e-167 554.6 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EPE36664.1 - 1.6e-22 79.4 0.2 3.5e-22 78.3 0.2 1.6 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EPE36664.1 - 2e-11 44.4 0.5 2.9e-07 31.0 0.1 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EPE36664.1 - 5.3e-10 39.3 0.3 1.2e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EPE36664.1 - 1.7e-05 25.1 0.2 0.27 11.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EPE36664.1 - 3e-05 24.5 0.1 0.00053 20.4 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EPE36664.1 - 3.3e-05 24.3 0.7 0.094 13.1 0.3 2.3 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EPE36664.1 - 0.00039 20.4 0.3 0.059 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EPE36664.1 - 0.002 17.8 0.1 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 EPE36664.1 - 0.0038 17.5 0.5 0.011 16.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EPE36664.1 - 0.0044 16.6 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EPE36664.1 - 0.0075 15.6 0.3 0.023 14.0 0.1 1.9 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 EPE36664.1 - 0.013 14.8 0.1 0.72 9.2 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 EPE36664.1 - 0.016 14.5 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 EPE36664.1 - 0.029 14.1 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 EPE36664.1 - 0.031 13.6 0.1 0.095 12.0 0.0 1.9 2 0 0 2 2 2 0 KaiC DnaB_C PF03796.15 EPE36664.1 - 0.04 13.2 0.0 0.081 12.2 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 EPE36664.1 - 0.047 13.7 0.0 0.83 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EPE36664.1 - 0.048 13.2 0.2 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 EPE36664.1 - 0.089 12.5 0.4 1.2 8.8 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EPE36664.1 - 0.15 12.6 0.2 0.48 11.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain Homeodomain PF00046.29 EPE36665.1 - 4.2e-13 48.9 1.5 8.1e-13 48.0 1.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EPE36665.1 - 0.0014 18.5 0.9 0.0045 16.9 0.4 2.1 2 0 0 2 2 2 1 Homeobox KN domain FRB_dom PF08771.11 EPE36665.1 - 0.12 12.8 0.1 0.27 11.6 0.1 1.5 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain HET PF06985.11 EPE36667.1 - 7e-26 91.3 0.2 1.4e-25 90.3 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Coagulase PF08764.10 EPE36667.1 - 0.026 14.7 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Aldedh PF00171.22 EPE36668.1 - 1e-107 360.5 0.0 1.3e-107 360.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HLH PF00010.26 EPE36669.1 - 1.8e-12 47.0 0.1 3.3e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mitofilin PF09731.9 EPE36669.1 - 0.17 10.7 4.1 0.19 10.5 4.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Cellulase PF00150.18 EPE36670.1 - 5.8e-08 32.5 0.3 8.7e-08 31.9 0.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HsbA PF12296.8 EPE36672.1 - 0.13 12.7 0.0 13 6.2 0.0 2.3 1 1 1 2 2 2 0 Hydrophobic surface binding protein A Wza_C PF18412.1 EPE36672.1 - 0.16 11.7 0.0 0.4 10.5 0.0 1.7 1 0 0 1 1 1 0 Outer-membrane lipoprotein Wza C-terminal domain Glyco_hydro_43 PF04616.14 EPE36673.1 - 3.4e-52 177.5 4.2 4.1e-52 177.3 4.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FAD_binding_4 PF01565.23 EPE36674.1 - 1.4e-19 70.2 0.3 3.2e-19 69.0 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPE36674.1 - 8.4e-14 51.4 0.0 1.8e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like AAA PF00004.29 EPE36676.1 - 1.1e-18 68.0 0.0 3.8e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EPE36676.1 - 0.0005 20.4 0.2 0.0056 17.0 0.0 2.4 2 0 0 2 2 2 1 RNA helicase DUF4260 PF14079.6 EPE36677.1 - 0.21 11.6 3.1 0.34 10.9 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4260) Vac_ImportDeg PF09783.9 EPE36678.1 - 1.5e-67 226.4 1.4 1.9e-67 226.1 1.4 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.14 EPE36679.1 - 3.2e-72 241.3 0.1 3.6e-72 241.1 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein CRS1_YhbY PF01985.21 EPE36679.1 - 0.11 12.7 0.2 0.16 12.1 0.2 1.2 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain Adaptin_N PF01602.20 EPE36680.1 - 7.3e-94 315.2 7.6 1.5e-93 314.2 7.6 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EPE36680.1 - 6.6e-60 201.1 1.7 1.4e-59 200.0 1.7 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 EPE36680.1 - 3.4e-56 188.7 0.0 9.2e-56 187.3 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 EPE36680.1 - 8.5e-14 51.9 1.9 3.4e-10 40.2 0.0 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EPE36680.1 - 6.2e-06 26.5 6.3 0.017 15.5 0.0 5.5 2 1 2 5 5 5 2 HEAT repeats Coatomer_g_Cpla PF16381.5 EPE36680.1 - 0.00047 20.3 0.0 0.002 18.3 0.0 2.2 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 EPE36680.1 - 0.0021 18.2 0.2 3.3 8.2 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Pilus_CpaD PF09476.10 EPE36680.1 - 0.043 13.6 1.5 0.069 12.9 0.5 1.8 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) AP4E_app_platf PF14807.6 EPE36680.1 - 0.087 13.2 0.1 0.27 11.6 0.1 1.9 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform DAGK_cat PF00781.24 EPE36681.1 - 4.1e-24 84.6 0.0 1.5e-23 82.7 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.12 EPE36682.1 - 4e-68 229.4 0.0 4.5e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 SET PF00856.28 EPE36683.1 - 1.5e-20 74.3 0.0 3.7e-20 73.0 0.0 1.7 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 EPE36683.1 - 3.6e-06 27.6 4.0 2.4e-05 25.0 0.8 2.2 2 0 0 2 2 2 1 Pre-SET motif SAP18 PF06487.12 EPE36683.1 - 0.059 13.5 0.8 0.15 12.2 0.1 1.9 2 1 1 3 3 3 0 Sin3 associated polypeptide p18 (SAP18) p450 PF00067.22 EPE36686.1 - 1.3e-48 165.9 0.1 2.8e-24 85.7 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 CUE PF02845.16 EPE36687.1 - 8.3e-12 44.6 0.0 1.6e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 CUE domain UBA PF00627.31 EPE36687.1 - 0.2 11.6 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain Hva1_TUDOR PF11160.8 EPE36689.1 - 1.3e-12 47.6 4.0 1.3e-12 47.6 4.0 3.2 3 1 0 3 3 3 1 Hypervirulence associated proteins TUDOR domain SLC12 PF03522.15 EPE36689.1 - 1.9 7.4 17.5 2.4 7.1 17.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 MFS_1 PF07690.16 EPE36690.1 - 4.7e-38 131.0 49.7 5.1e-37 127.6 49.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE36690.1 - 1.1e-09 37.8 15.5 1.1e-09 37.8 15.5 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter Spore_III_AF PF09581.10 EPE36690.1 - 0.23 11.5 0.1 0.47 10.5 0.1 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Collagen PF01391.18 EPE36691.1 - 2.3e-26 91.3 118.7 7.8e-09 35.2 25.2 6.0 3 2 2 5 5 5 5 Collagen triple helix repeat (20 copies) WSC PF01822.19 EPE36691.1 - 7.7e-15 54.9 11.3 7.7e-15 54.9 11.3 1.9 2 0 0 2 2 2 1 WSC domain Inhibitor_I36 PF03995.13 EPE36692.1 - 0.0054 16.6 0.5 0.0054 16.6 0.5 2.2 2 0 0 2 2 2 1 Peptidase inhibitor family I36 DUF5516 PF17637.2 EPE36693.1 - 0.1 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5516) NACHT PF05729.12 EPE36694.1 - 0.0013 18.7 0.5 0.0055 16.6 0.5 1.9 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EPE36694.1 - 0.14 12.6 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain T3RM_EcoP15I_C PF18273.1 EPE36695.1 - 0.024 14.9 0.1 0.079 13.3 0.1 1.9 1 0 0 1 1 1 0 Type III R-M EcoP15I C-terminal domain KTI12 PF08433.10 EPE36695.1 - 0.042 13.3 4.0 0.074 12.5 0.6 2.3 1 1 1 2 2 2 0 Chromatin associated protein KTI12 BAG PF02179.16 EPE36695.1 - 0.044 14.2 0.7 0.16 12.4 0.7 1.9 1 0 0 1 1 1 0 BAG domain IL32 PF15225.6 EPE36695.1 - 0.09 13.2 0.4 0.22 11.9 0.4 1.7 1 0 0 1 1 1 0 Interleukin 32 T3SSipB PF16535.5 EPE36695.1 - 0.16 12.4 1.4 1.5 9.3 0.2 2.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB FliD_N PF02465.18 EPE36695.1 - 0.41 11.4 6.9 5.4 7.8 5.2 2.7 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Mt_ATP-synt_B PF05405.14 EPE36695.1 - 0.61 9.7 8.6 0.46 10.1 1.1 2.6 2 1 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) IZUMO PF15005.6 EPE36695.1 - 0.77 10.3 3.0 0.72 10.4 0.9 2.0 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF4795 PF16043.5 EPE36695.1 - 1.7 8.2 9.4 0.59 9.7 3.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) SlyX PF04102.12 EPE36695.1 - 6.1 7.5 6.3 5.7 7.6 0.6 3.5 3 1 0 3 3 3 0 SlyX UQ_con PF00179.26 EPE36696.1 - 1.3e-42 144.8 0.0 1.4e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPE36696.1 - 6.3e-05 22.7 0.0 7.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EPE36696.1 - 0.03 14.6 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain RabGAP-TBC PF00566.18 EPE36697.1 - 7.8e-36 123.7 0.0 1.7e-35 122.6 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Kinesin PF00225.23 EPE36698.1 - 2.7e-54 184.3 0.0 2.2e-53 181.4 0.0 2.1 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EPE36698.1 - 7.9e-10 38.9 0.0 1.5e-06 28.2 0.0 2.9 3 0 0 3 3 3 2 Microtubule binding FAM76 PF16046.5 EPE36698.1 - 0.044 13.1 1.1 0.08 12.3 1.1 1.3 1 0 0 1 1 1 0 FAM76 protein HALZ PF02183.18 EPE36698.1 - 0.07 13.4 0.3 0.48 10.7 0.8 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper SMC_ScpA PF02616.14 EPE36698.1 - 0.54 10.1 3.1 0.91 9.4 3.1 1.2 1 0 0 1 1 1 0 Segregation and condensation protein ScpA Mitofilin PF09731.9 EPE36698.1 - 1.4 7.7 11.1 2 7.1 11.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF812 PF05667.11 EPE36698.1 - 1.4 7.7 13.6 2.2 7.1 12.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF1640 PF07798.11 EPE36698.1 - 2.3 8.3 10.7 13 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF4407 PF14362.6 EPE36698.1 - 2.3 7.5 3.9 3.8 6.8 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_S24 PF00717.23 EPE36699.1 - 2e-07 30.9 0.0 3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S9 PF00326.21 EPE36701.1 - 5.6e-38 130.5 0.0 8.4e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EPE36701.1 - 2.1e-08 34.0 0.0 5.4e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EPE36701.1 - 3.6e-06 26.8 0.0 4.4e-05 23.2 0.1 2.1 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.28 EPE36701.1 - 1.6e-05 24.0 0.0 2.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 EPE36701.1 - 6.1e-05 22.4 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPE36701.1 - 7.3e-05 22.5 0.0 0.13 11.9 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EPE36701.1 - 0.0065 16.6 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein BAAT_C PF08840.11 EPE36701.1 - 0.04 13.8 0.0 0.61 10.0 0.0 2.2 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1266 PF06889.11 EPE36701.1 - 0.088 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Esterase_phd PF10503.9 EPE36701.1 - 0.12 11.8 0.2 0.29 10.6 0.2 1.6 1 1 0 1 1 1 0 Esterase PHB depolymerase PD40 PF07676.12 EPE36701.1 - 0.14 12.1 0.1 0.4 10.7 0.1 1.8 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Glyco_hydro_31 PF01055.26 EPE36702.1 - 3.1e-151 504.5 2.3 4e-151 504.1 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EPE36702.1 - 2.7e-34 117.8 0.0 4.6e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Amidase PF01425.21 EPE36703.1 - 1.3e-100 337.5 0.0 1.6e-100 337.3 0.0 1.1 1 0 0 1 1 1 1 Amidase FAD_binding_3 PF01494.19 EPE36704.1 - 1.6e-74 251.2 0.0 2.2e-74 250.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EPE36704.1 - 4.3e-27 95.2 0.0 1e-26 93.9 0.0 1.6 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Inj_translocase PF16928.5 EPE36704.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome Ald_Xan_dh_C2 PF02738.18 EPE36705.1 - 1.3e-202 674.1 0.8 1.8e-202 673.7 0.8 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EPE36705.1 - 1.8e-40 138.5 0.0 3.7e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EPE36705.1 - 3.2e-33 114.0 0.0 2.6e-32 111.0 0.0 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 EPE36705.1 - 2.4e-25 88.3 0.0 5.8e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 EPE36705.1 - 4.5e-20 72.1 0.0 9.4e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 EPE36705.1 - 5.4e-09 35.9 0.0 2e-08 34.0 0.0 2.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_2 PF03446.15 EPE36705.1 - 0.086 13.0 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Oxidored_FMN PF00724.20 EPE36706.1 - 2.6e-86 290.0 0.0 3.5e-86 289.6 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TMP-TENI PF02581.17 EPE36706.1 - 0.21 10.9 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase Fungal_trans PF04082.18 EPE36707.1 - 9.3e-37 126.5 5.5 1.7e-36 125.7 5.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPE36707.1 - 0.0006 20.1 20.0 0.0016 18.8 2.9 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE36707.1 - 0.0041 17.8 10.2 0.46 11.4 1.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger DUF918 PF06033.11 EPE36707.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) FAD_binding_3 PF01494.19 EPE36708.1 - 1.2e-19 70.8 0.0 1.9e-13 50.4 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EPE36708.1 - 4.4e-09 36.4 5.4 2.2e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EPE36708.1 - 8.9e-08 31.4 3.5 0.00024 20.1 0.1 2.1 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 EPE36708.1 - 1.7e-07 30.7 2.8 0.0078 15.5 0.6 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPE36708.1 - 1.1e-06 27.9 0.1 1.7e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPE36708.1 - 1.9e-05 24.8 1.0 8.7e-05 22.7 0.6 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EPE36708.1 - 0.00011 21.6 1.5 0.11 11.7 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EPE36708.1 - 0.0011 17.8 3.8 0.01 14.6 3.8 1.9 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EPE36708.1 - 0.007 15.5 2.4 0.007 15.5 2.4 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EPE36708.1 - 0.019 15.5 1.6 0.035 14.7 0.4 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EPE36708.1 - 0.076 12.9 0.4 0.13 12.2 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 EPE36708.1 - 0.08 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Rossmann-like domain Pyr_redox_3 PF13738.6 EPE36708.1 - 0.097 11.9 0.1 0.65 9.2 0.1 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPE36708.1 - 0.12 12.4 3.5 0.8 9.7 3.5 2.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding SE PF08491.10 EPE36708.1 - 0.12 11.4 0.0 0.45 9.5 0.0 1.8 1 1 0 1 1 1 0 Squalene epoxidase GIDA PF01134.22 EPE36708.1 - 0.22 10.6 4.9 1.3 8.0 3.9 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A CFEM PF05730.11 EPE36709.1 - 6.8e-13 48.5 8.7 1.6e-12 47.4 8.7 1.6 1 0 0 1 1 1 1 CFEM domain Tubulin_3 PF14881.6 EPE36710.1 - 4.6e-78 261.0 0.1 1.9e-77 259.0 0.0 2.0 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.9 EPE36710.1 - 3.5e-41 140.2 4.3 5.4e-41 139.6 0.1 2.8 3 0 0 3 3 3 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EPE36710.1 - 0.00053 20.2 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain AhpC-TSA_2 PF13911.6 EPE36711.1 - 7.4e-06 26.1 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EPE36711.1 - 7.7e-06 25.8 0.0 1.2e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EPE36711.1 - 0.004 16.9 0.0 0.53 10.0 0.0 2.1 2 0 0 2 2 2 2 Redoxin HET PF06985.11 EPE36712.1 - 1.1e-24 87.5 0.0 2e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NADase_NGA PF07461.11 EPE36712.1 - 0.0038 16.2 0.0 0.0054 15.7 0.0 1.1 1 0 0 1 1 1 1 Nicotine adenine dinucleotide glycohydrolase (NADase) tRNA-synt_1c PF00749.21 EPE36713.1 - 3.1e-93 312.1 0.0 4.2e-93 311.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EPE36713.1 - 6.7e-33 114.0 0.8 1.7e-32 112.7 0.6 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 EPE36713.1 - 0.034 14.3 0.0 0.26 11.5 0.0 2.4 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPE36713.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Bromodomain PF00439.25 EPE36714.1 - 1.3e-23 82.8 0.1 2.5e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EPE36714.1 - 3.2e-07 30.6 0.0 6.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE36714.1 - 1.5e-06 28.2 0.7 5.5e-06 26.3 0.2 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPE36714.1 - 0.00043 20.7 0.1 0.0012 19.3 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CoA_transf_3 PF02515.17 EPE36715.1 - 4e-42 144.7 0.0 5.6e-41 140.9 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III MFS_1 PF07690.16 EPE36717.1 - 1.1e-39 136.4 35.4 1.1e-39 136.4 35.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE36717.1 - 1.1e-08 34.4 28.2 1.4e-08 34.1 27.1 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EPE36717.1 - 3.2e-07 29.2 2.2 6.3e-07 28.2 2.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EPE36717.1 - 7.7 4.7 17.5 0.087 11.1 4.3 3.4 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 EPE36718.1 - 8.8e-12 44.6 0.0 1.7e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3336 PF11815.8 EPE36719.1 - 2e-49 166.9 2.5 3e-49 166.3 2.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EPE36719.1 - 2.9e-17 63.5 0.5 4.5e-16 59.6 0.2 2.6 2 1 0 2 2 2 1 Patatin-like phospholipase DUF2048 PF09752.9 EPE36719.1 - 0.045 12.9 0.0 0.52 9.3 0.0 2.1 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Arf PF00025.21 EPE36720.1 - 4.2e-61 205.4 0.0 3.2e-60 202.6 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EPE36720.1 - 1.9e-12 47.0 0.1 1.5e-08 34.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EPE36720.1 - 3e-08 33.9 0.0 4.1e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EPE36720.1 - 1.6e-06 27.6 0.0 2.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EPE36720.1 - 1.7e-06 28.1 0.0 2.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EPE36720.1 - 5.4e-06 25.9 0.0 7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EPE36720.1 - 4.1e-05 23.2 0.0 0.00011 21.8 0.0 1.6 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 EPE36720.1 - 0.0052 16.3 0.1 0.062 12.8 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF2457 PF10446.9 EPE36721.1 - 4.4e-166 553.7 65.0 1.1e-107 361.1 43.6 3.9 3 1 1 4 4 4 2 Protein of unknown function (DUF2457) TFIIA PF03153.13 EPE36721.1 - 0.00076 19.6 11.1 0.00076 19.6 11.1 2.1 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 EPE36721.1 - 0.25 9.5 35.5 0.0074 14.6 27.6 2.0 2 0 0 2 2 2 0 Nop14-like family ATP-synt_DE_N PF02823.16 EPE36722.1 - 5.3e-17 61.5 0.1 7.5e-17 61.0 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Phage_GP20 PF06810.11 EPE36723.1 - 0.06 13.2 2.3 0.1 12.4 2.3 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 UNC-79 PF14776.6 EPE36723.1 - 0.11 11.2 2.0 0.19 10.4 2.0 1.3 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Spc24 PF08286.11 EPE36723.1 - 0.4 10.9 2.3 1 9.7 2.3 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Acetyltransf_1 PF00583.25 EPE36724.1 - 4.8e-07 30.0 0.0 6.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPE36724.1 - 1.2e-06 28.5 0.0 1.8e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPE36724.1 - 0.0001 22.2 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EPE36724.1 - 0.00097 19.5 0.0 0.0015 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPE36724.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SSDP PF04503.13 EPE36725.1 - 0.024 14.9 4.9 0.042 14.1 4.9 1.4 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP DUF1682 PF07946.14 EPE36725.1 - 0.063 12.5 0.0 0.084 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) HET PF06985.11 EPE36726.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) DUF1996 PF09362.10 EPE36728.1 - 9.9e-80 267.9 1.2 1.2e-79 267.6 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Glyco_hydro_36 PF17167.4 EPE36729.1 - 2.3e-66 224.2 0.0 4e-66 223.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_transf_36 PF06165.11 EPE36729.1 - 1.1e-32 113.4 0.1 1.8e-32 112.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 36 Bac_rhamnosid6H PF17389.2 EPE36729.1 - 0.00036 19.9 0.1 0.00087 18.6 0.1 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain GDE_C PF06202.14 EPE36729.1 - 0.0031 16.5 0.0 0.0094 14.9 0.0 1.7 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Glyco_hydro_65C PF03633.15 EPE36729.1 - 0.0045 16.9 0.0 0.015 15.2 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain MFS_1 PF07690.16 EPE36730.1 - 8e-22 77.6 15.4 1.1e-21 77.2 15.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily GDPD PF03009.17 EPE36731.1 - 1.2e-42 146.5 0.0 2e-42 145.7 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EPE36731.1 - 3.1e-23 82.2 0.1 1.1e-14 54.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPE36731.1 - 5.5e-17 60.1 0.6 2e-05 24.6 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EPE36731.1 - 2.6e-16 59.5 0.8 0.0001 22.5 0.0 3.9 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EPE36731.1 - 1.5e-15 56.8 0.4 0.00066 20.0 0.0 5.5 4 1 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EPE36731.1 - 5.6e-15 55.5 1.2 4.4e-06 27.1 0.0 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.19 EPE36731.1 - 2.3e-06 27.8 0.9 5.2e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 SPX domain Aldo_ket_red PF00248.21 EPE36732.1 - 5.9e-58 196.4 0.0 6.6e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PSD5 PF07637.11 EPE36733.1 - 1.8e-10 41.0 0.2 52 4.3 0.0 8.2 5 4 3 8 8 8 0 Protein of unknown function (DUF1595) tRNA_int_endo_N PF02778.14 EPE36733.1 - 0.0033 17.1 6.2 13 5.5 0.1 4.9 1 1 3 4 4 4 2 tRNA intron endonuclease, N-terminal domain IglC PF11550.8 EPE36733.1 - 0.0087 15.5 0.1 34 3.8 0.0 3.8 3 1 1 4 4 4 2 Intracellular growth locus C protein DUF276 PF03434.13 EPE36733.1 - 0.02 14.1 0.3 33 3.5 0.0 4.2 2 2 1 4 4 4 0 DUF276 ToxN_toxin PF13958.6 EPE36733.1 - 0.092 13.0 0.5 6.7 6.9 0.3 3.4 1 1 1 2 2 2 0 Toxin ToxN, type III toxin-antitoxin system Ras PF00071.22 EPE36734.1 - 2.5e-57 193.0 0.0 3e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE36734.1 - 1e-33 116.1 0.0 1.5e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE36734.1 - 2.3e-13 50.0 0.0 3.1e-13 49.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EPE36734.1 - 2.4e-05 23.9 0.0 3.7e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EPE36734.1 - 0.00014 21.9 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EPE36734.1 - 0.00019 20.9 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EPE36734.1 - 0.00071 20.0 0.0 0.001 19.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EPE36734.1 - 0.018 15.0 0.1 1.8 8.4 0.0 2.6 2 1 0 2 2 2 0 RsgA GTPase Kri1_C PF12936.7 EPE36735.1 - 2.2e-31 107.9 0.2 2.2e-31 107.9 0.2 4.1 3 1 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 EPE36735.1 - 9e-29 100.1 17.5 9e-29 100.1 17.5 5.5 5 2 1 6 6 6 1 KRI1-like family ECF_trnsprt PF12822.7 EPE36736.1 - 0.026 14.6 0.5 0.026 14.6 0.5 1.4 2 0 0 2 2 2 0 ECF transporter, substrate-specific component EBP PF05241.12 EPE36736.1 - 0.8 9.1 7.1 1.2 8.6 6.8 1.7 1 1 0 1 1 1 0 Emopamil binding protein Scs3p PF10261.9 EPE36737.1 - 1.5e-76 257.2 2.4 1.8e-76 256.9 2.4 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM APH PF01636.23 EPE36740.1 - 1.2e-12 48.3 0.0 5e-12 46.3 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE36740.1 - 0.0065 16.1 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EPE36740.1 - 0.013 14.4 0.1 0.019 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 EPE36740.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Glyco_hydro_3_C PF01915.22 EPE36741.1 - 2.8e-45 154.8 0.0 5.8e-45 153.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE36741.1 - 9.3e-40 136.9 0.0 1.5e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE36741.1 - 1.8e-16 60.0 0.1 3.9e-16 58.9 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain K_trans PF02705.16 EPE36742.1 - 7e-184 612.3 21.5 9.1e-184 611.9 21.5 1.1 1 0 0 1 1 1 1 K+ potassium transporter Fungal_trans PF04082.18 EPE36743.1 - 1.9e-29 102.6 0.0 3.5e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE36743.1 - 1.9e-09 37.5 10.9 3.1e-09 36.8 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polyoma_coat2 PF00761.20 EPE36743.1 - 0.067 12.9 2.5 0.13 12.0 2.5 1.4 1 0 0 1 1 1 0 Polyomavirus coat protein VASt PF16016.5 EPE36744.1 - 2.3e-35 122.2 0.3 5.4e-35 121.1 0.3 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 EPE36744.1 - 4.1e-18 66.0 0.0 7.5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EPE36744.1 - 5.4e-08 33.3 0.1 1.8e-07 31.6 0.1 2.0 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 EPE36744.1 - 0.012 15.4 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 GRAM domain DUF3074 PF11274.8 EPE36745.1 - 8.2e-63 211.7 0.5 3.3e-62 209.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) V_ATPase_I PF01496.19 EPE36745.1 - 4.6 5.0 15.2 8.2 4.2 15.2 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.6 EPE36745.1 - 5.4 5.5 21.0 8.3 4.9 21.0 1.2 1 0 0 1 1 1 0 AAA domain APH PF01636.23 EPE36747.1 - 3.3e-10 40.3 0.3 4.7e-10 39.8 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EPE36747.1 - 0.0012 17.8 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EPE36747.1 - 0.0033 17.0 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase GST_N_3 PF13417.6 EPE36748.1 - 2.8e-11 43.7 0.1 6.9e-11 42.4 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPE36748.1 - 2.9e-10 40.3 0.1 5.1e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPE36748.1 - 3.3e-05 23.8 0.0 6.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 EPE36748.1 - 0.00087 19.1 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_C_3 PF14497.6 EPE36748.1 - 0.0023 18.1 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EPE36748.1 - 0.019 15.3 0.0 0.04 14.2 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 EPE36748.1 - 0.034 14.7 0.0 0.059 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EPE36748.1 - 0.16 12.2 0.0 0.75 10.1 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Methyltr_RsmB-F PF01189.17 EPE36749.1 - 1.8e-17 63.7 0.0 2.6e-11 43.5 0.0 2.5 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F DUF1580 PF07618.11 EPE36749.1 - 0.16 11.6 0.3 13 5.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1580) Spt5_N PF11942.8 EPE36749.1 - 1.6 9.8 8.4 0.21 12.6 3.5 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Abhydrolase_6 PF12697.7 EPE36751.1 - 0.012 16.2 0.0 0.03 14.9 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPE36751.1 - 0.13 11.5 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 EPE36751.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase CBM_1 PF00734.18 EPE36753.1 - 1.5e-08 34.4 9.7 3.7e-08 33.2 9.7 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Totivirus_coat PF05518.11 EPE36753.1 - 3.8 5.4 9.4 4.6 5.2 9.4 1.0 1 0 0 1 1 1 0 Totivirus coat protein Prp18 PF02840.15 EPE36754.1 - 3.3e-51 173.1 0.0 3.3e-51 173.1 0.0 2.5 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 EPE36754.1 - 1.4e-12 46.9 0.9 1.4e-12 46.9 0.9 2.8 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like DUF4778 PF16008.5 EPE36754.1 - 1.3 9.0 8.6 2.4 8.2 8.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) CDC27 PF09507.10 EPE36754.1 - 2.7 7.3 23.3 3.8 6.8 23.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FAM60A PF15396.6 EPE36754.1 - 6.9 6.6 10.8 11 5.9 10.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A SAP18 PF06487.12 EPE36755.1 - 5.2e-52 175.7 0.0 6.2e-52 175.5 0.0 1.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) GST_N_2 PF13409.6 EPE36757.1 - 9.9e-10 38.6 0.1 1.8e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EPE36757.1 - 4.1e-09 36.7 0.1 6.6e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPE36757.1 - 2.6e-08 34.1 0.0 4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain KASH_CCD PF14662.6 EPE36759.1 - 0.0056 16.5 1.5 0.092 12.6 0.1 2.2 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH T3SSipB PF16535.5 EPE36759.1 - 0.0091 16.5 1.6 0.014 15.9 0.8 1.7 1 1 0 1 1 1 1 Type III cell invasion protein SipB DUF745 PF05335.13 EPE36759.1 - 0.016 14.9 0.9 0.025 14.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF745) PHA_synth_III_E PF09712.10 EPE36759.1 - 0.026 13.6 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Golgin_A5 PF09787.9 EPE36759.1 - 0.027 14.0 4.1 0.036 13.5 4.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1415 PF07209.12 EPE36759.1 - 0.035 13.8 2.0 0.48 10.2 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1415) KinB_sensor PF16767.5 EPE36759.1 - 0.038 14.5 0.7 0.067 13.6 0.7 1.5 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB Syntaxin-6_N PF09177.11 EPE36759.1 - 0.05 14.2 0.5 0.12 12.9 0.5 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Snf7 PF03357.21 EPE36759.1 - 0.055 13.1 0.5 0.11 12.1 0.5 1.5 1 0 0 1 1 1 0 Snf7 Jnk-SapK_ap_N PF09744.9 EPE36759.1 - 0.056 13.7 3.1 0.093 12.9 3.1 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Apolipoprotein PF01442.18 EPE36759.1 - 0.066 13.1 1.7 0.35 10.7 1.7 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF5449 PF17528.2 EPE36759.1 - 0.11 12.3 0.1 0.21 11.3 0.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5449) SesA PF17107.5 EPE36759.1 - 0.13 12.5 2.8 0.11 12.6 0.4 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Sec34 PF04136.15 EPE36759.1 - 0.15 11.9 3.1 0.31 10.9 3.1 1.6 1 1 0 1 1 1 0 Sec34-like family Fib_alpha PF08702.10 EPE36759.1 - 0.32 11.2 4.1 0.73 10.0 2.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CREPT PF16566.5 EPE36759.1 - 0.36 11.0 2.9 0.64 10.2 1.6 2.0 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour APG6_N PF17675.1 EPE36759.1 - 0.68 10.5 5.1 1.4 9.4 5.1 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region Ank_5 PF13857.6 EPE36760.1 - 0.0032 17.7 0.8 0.052 13.9 0.3 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPE36760.1 - 0.0064 16.9 0.9 0.08 13.5 0.3 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 EPE36760.1 - 0.0088 16.6 0.2 0.056 14.0 0.1 2.3 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPE36760.1 - 0.017 15.7 0.2 0.46 11.1 0.1 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) PHD PF00628.29 EPE36761.1 - 9.5e-06 25.4 6.1 1.6e-05 24.7 6.1 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 EPE36761.1 - 0.00085 19.9 0.1 0.0027 18.2 0.0 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.6 EPE36761.1 - 0.024 14.9 0.8 0.05 13.9 0.8 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain OATP PF03137.20 EPE36762.1 - 2.9 6.1 7.5 6.1 5.0 1.1 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family zf-C2H2 PF00096.26 EPE36763.1 - 0.043 14.3 3.6 0.043 14.3 3.6 2.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPE36763.1 - 0.082 13.4 0.9 6.6 7.4 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Astro_capsid_p PF12226.8 EPE36763.1 - 3 6.9 7.0 0.2 10.8 0.8 1.9 2 0 0 2 2 2 0 Turkey astrovirus capsid protein DUF3602 PF12223.8 EPE36764.1 - 9.9e-11 42.1 22.9 1.7e-06 28.5 2.6 2.5 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) PNPase_C PF12111.8 EPE36764.1 - 2.2 7.8 8.5 14 5.2 0.0 3.5 3 0 0 3 3 3 0 Polyribonucleotide phosphorylase C terminal SesA PF17107.5 EPE36765.1 - 3.8e-37 127.2 0.0 1.7e-36 125.1 0.0 2.2 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 EPE36765.1 - 1e-09 38.5 2.8 2.3e-08 34.1 2.5 2.8 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EPE36765.1 - 9.2e-06 26.1 0.0 3e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EPE36765.1 - 0.0068 16.9 0.1 0.027 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPE36765.1 - 0.011 16.0 0.1 0.067 13.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EPE36765.1 - 0.041 14.4 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 EPE36765.1 - 0.043 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF1059 PF06348.11 EPE36765.1 - 0.26 11.5 1.0 0.5 10.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) SH3_1 PF00018.28 EPE36766.1 - 6.2e-11 41.7 0.0 1.3e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain CorA PF01544.18 EPE36766.1 - 7.6e-10 38.6 0.0 7.6e-10 38.6 0.0 2.5 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein SH3_9 PF14604.6 EPE36766.1 - 3.5e-08 33.2 0.0 8.4e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EPE36766.1 - 1.4e-06 27.8 0.0 3.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain LMBR1 PF04791.16 EPE36766.1 - 0.062 12.2 0.2 0.12 11.2 0.2 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Phage_holin_3_6 PF07332.11 EPE36766.1 - 0.14 12.2 1.1 0.32 11.0 1.1 1.6 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III WDCP PF15390.6 EPE36766.1 - 0.65 8.3 4.7 1.1 7.6 4.7 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family zf-H2C2_2 PF13465.6 EPE36767.1 - 6.6e-05 23.1 3.3 6.6e-05 23.1 3.3 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 EPE36767.1 - 7.1e-05 23.0 19.9 8.4e-05 22.8 2.8 3.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPE36767.1 - 0.00028 21.5 1.7 0.00028 21.5 1.7 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EPE36767.1 - 0.0031 17.5 1.1 0.02 14.9 1.3 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPE36767.1 - 0.0069 16.6 2.4 0.0095 16.2 0.7 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 EPE36767.1 - 0.22 11.8 3.2 0.7 10.2 3.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 EPE36767.1 - 8.5 7.1 12.0 0.87 10.3 2.7 3.5 2 1 2 4 4 4 0 FOXP coiled-coil domain MJ1316 PF04457.12 EPE36768.1 - 1.6e-16 60.8 0.1 5.6e-16 59.0 0.1 2.0 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain DUF433 PF04255.14 EPE36768.1 - 0.12 12.2 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF433) DUF1295 PF06966.12 EPE36769.1 - 1.3e-38 132.9 9.8 1.7e-38 132.4 9.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Topoisom_bac PF01131.20 EPE36770.1 - 2.8e-100 336.2 0.0 2.8e-94 316.5 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 EPE36770.1 - 5.5e-18 65.1 0.0 1.2e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Toprim domain FXMRP1_C_core PF12235.8 EPE36770.1 - 1.7 9.3 4.3 3.5 8.3 4.3 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal FoP_duplication PF13865.6 EPE36770.1 - 6.5 7.4 10.7 14 6.3 10.7 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Stb3 PF10330.9 EPE36771.1 - 3.1e-38 129.7 0.0 4.8e-38 129.1 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein DNA_pol_phi PF04931.13 EPE36771.1 - 8.7 4.3 5.7 12 3.8 5.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pam16 PF03656.13 EPE36773.1 - 2.5e-07 30.8 0.2 5.6e-07 29.6 0.2 1.6 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 EPE36773.1 - 3.2e-05 24.0 0.0 5.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 EPE36773.1 - 0.023 14.3 1.0 0.023 14.3 1.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) DUF4538 PF15061.6 EPE36773.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Ribosomal_L24e PF01246.20 EPE36774.1 - 3.1e-06 27.3 0.3 3.1e-06 27.3 0.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e DUF3293 PF11697.8 EPE36774.1 - 0.024 15.1 0.1 0.042 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) SnoaL_4 PF13577.6 EPE36775.1 - 0.001 19.2 0.2 0.0024 18.0 0.2 1.6 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 EPE36775.1 - 0.0097 16.5 0.0 0.013 16.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EPE36775.1 - 0.012 15.9 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) CiPC PF15800.5 EPE36776.1 - 0.23 11.2 13.3 0.33 10.6 13.3 1.2 1 0 0 1 1 1 0 Clock interacting protein circadian Lin-8 PF03353.15 EPE36776.1 - 0.38 10.3 10.5 0.057 13.0 7.0 1.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist PI3K_1B_p101 PF10486.9 EPE36776.1 - 3.1 5.5 12.8 4.2 5.0 12.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Mit_ribos_Mrp51 PF11709.8 EPE36778.1 - 1.5e-126 422.9 0.3 1.8e-126 422.6 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Gp-FAR-1 PF05823.12 EPE36779.1 - 0.053 13.9 0.1 0.14 12.5 0.1 1.7 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TMEM51 PF15345.6 EPE36779.1 - 1.5 8.6 5.4 0.22 11.3 0.4 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 Aminotran_1_2 PF00155.21 EPE36780.1 - 9.2e-17 61.2 0.0 1.2e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EPE36780.1 - 0.0021 16.9 0.0 0.019 13.8 0.0 2.1 2 1 0 2 2 2 1 Alanine-glyoxylate amino-transferase Carbam_trans_N PF02543.15 EPE36780.1 - 0.018 14.7 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus F1F0-ATPsyn_F PF10791.9 EPE36782.1 - 1.1e-41 141.2 0.4 1.3e-41 141.0 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 EPE36782.1 - 0.0033 17.8 0.1 0.0043 17.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.12 EPE36783.1 - 8.7e-37 125.3 1.8 8.7e-37 125.3 1.8 1.6 2 0 0 2 2 2 1 ETC complex I subunit conserved region HA2 PF04408.23 EPE36784.1 - 1.1e-22 80.3 2.4 1.4e-22 80.0 0.1 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EPE36784.1 - 1.9e-22 79.4 0.0 3.8e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EPE36784.1 - 8.4e-14 51.9 0.0 2.5e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 EPE36784.1 - 3.3e-10 40.2 1.4 7.1e-10 39.1 1.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 EPE36784.1 - 8.3e-06 25.7 0.1 1.8e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EPE36784.1 - 0.00024 21.4 0.0 0.00063 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPE36784.1 - 0.00041 20.1 0.1 0.00093 19.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EPE36784.1 - 0.00059 19.0 0.2 0.0019 17.3 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 EPE36784.1 - 0.006 16.9 0.2 0.012 15.9 0.2 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EPE36784.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 EPE36784.1 - 0.058 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EPE36784.1 - 0.065 13.3 0.1 0.49 10.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EPE36784.1 - 0.14 12.6 0.2 1.7 9.2 0.2 2.5 1 1 0 1 1 1 0 ABC transporter Motile_Sperm PF00635.26 EPE36786.1 - 5.1e-25 87.4 0.7 2.9e-24 85.0 0.3 2.1 1 1 1 2 2 2 1 MSP (Major sperm protein) domain ASH PF15780.5 EPE36786.1 - 0.00079 19.6 0.1 0.0023 18.1 0.1 1.7 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixG_C PF11614.8 EPE36786.1 - 0.018 15.3 0.1 0.041 14.1 0.1 1.6 1 1 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase SLT_2 PF13406.6 EPE36786.1 - 0.071 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain DUF756 PF05506.12 EPE36786.1 - 0.11 13.4 0.0 0.37 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF756) UBX PF00789.20 EPE36787.1 - 2.6e-06 27.5 0.0 6.1e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 EPE36787.1 - 0.0023 17.8 0.0 0.007 16.2 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain zf-met PF12874.7 EPE36787.1 - 0.028 14.8 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EPE36787.1 - 0.068 13.5 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Utp11 PF03998.13 EPE36787.1 - 0.071 13.0 20.4 0.11 12.4 20.4 1.3 1 0 0 1 1 1 0 Utp11 protein zf-C2H2 PF00096.26 EPE36787.1 - 0.24 11.9 0.1 0.53 10.8 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type SOBP PF15279.6 EPE36787.1 - 2.1 8.9 5.4 2.5 8.6 5.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein VIR_N PF15912.5 EPE36787.1 - 4.1 6.9 9.9 6.3 6.3 9.9 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Rad52_Rad22 PF04098.15 EPE36788.1 - 1.4e-60 203.7 0.0 2.1e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein GCIP PF13324.6 EPE36790.1 - 0.26 10.9 1.6 0.28 10.8 1.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting NOA36 PF06524.12 EPE36790.1 - 1.8 7.8 5.0 2.3 7.5 5.0 1.1 1 0 0 1 1 1 0 NOA36 protein Aminotran_5 PF00266.19 EPE36791.1 - 1.1e-13 51.0 0.0 1.3e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V SepSecS PF05889.13 EPE36791.1 - 0.0045 15.7 0.0 0.0058 15.4 0.0 1.1 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 EPE36791.1 - 0.025 13.7 0.0 9.2 5.3 0.0 2.8 3 0 0 3 3 3 0 Aminotransferase class I and II RecO_N PF11967.8 EPE36791.1 - 0.21 11.6 0.2 3.8 7.5 0.1 2.3 2 0 0 2 2 2 0 Recombination protein O N terminal Meth_synt_2 PF01717.18 EPE36792.1 - 5.8e-153 508.9 0.0 3.5e-147 489.9 0.0 2.7 3 1 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EPE36792.1 - 4.9e-118 394.2 0.2 1.3e-111 373.1 0.0 3.3 4 0 0 4 4 4 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EPE36792.1 - 0.00058 19.1 0.1 0.051 12.7 0.0 2.8 3 1 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) VbhA PF18495.1 EPE36792.1 - 0.025 14.4 0.2 15 5.5 0.0 3.1 3 0 0 3 3 3 0 Antitoxin VbhA RasGEF PF00617.19 EPE36793.1 - 1.9e-55 187.8 0.0 4.4e-55 186.6 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EPE36793.1 - 4.6e-17 62.2 0.0 2.6e-16 59.7 0.0 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.6 EPE36793.1 - 1.2e-06 28.3 0.0 2.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EPE36793.1 - 3.8e-05 23.2 0.0 8.2e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain FA_desaturase PF00487.24 EPE36794.1 - 7.1e-25 88.3 13.2 1.3e-24 87.5 13.2 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EPE36794.1 - 7.1e-20 70.2 0.2 1.1e-19 69.6 0.2 1.3 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Aconitase PF00330.20 EPE36796.1 - 8.9e-148 493.1 0.0 1.1e-147 492.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EPE36796.1 - 2.9e-39 134.4 0.0 4.6e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain WD40 PF00400.32 EPE36797.1 - 2.8e-41 138.7 19.0 4.5e-09 36.8 0.0 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE36797.1 - 1.4e-13 50.9 0.7 0.0049 17.1 0.0 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPE36797.1 - 1.9e-09 36.9 0.6 0.041 12.8 0.0 4.7 2 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EPE36797.1 - 2.9e-05 22.9 4.2 0.091 11.4 0.1 4.4 3 1 2 5 5 5 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EPE36797.1 - 7.7e-05 21.8 0.1 7.7e-05 21.8 0.1 2.8 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 EPE36797.1 - 0.00015 20.3 0.0 0.00035 19.0 0.0 1.5 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Hira PF07569.11 EPE36797.1 - 0.00081 19.2 3.4 0.89 9.2 0.1 4.0 1 1 3 4 4 4 1 TUP1-like enhancer of split HPS3_N PF14761.6 EPE36797.1 - 0.0025 17.4 0.0 0.021 14.4 0.0 2.2 2 1 1 3 3 3 1 Hermansky-Pudlak syndrome 3 eIF2A PF08662.11 EPE36797.1 - 0.0028 17.6 1.9 0.048 13.5 0.1 2.9 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EPE36797.1 - 0.015 14.3 0.0 0.028 13.5 0.0 1.3 1 1 0 1 1 1 0 Coatomer WD associated region HEAT PF02985.22 EPE36798.1 - 2.8e-10 39.6 0.9 0.61 10.5 0.0 5.3 5 0 0 5 5 5 4 HEAT repeat HEAT_2 PF13646.6 EPE36798.1 - 2.5e-07 31.0 0.0 1.9e-05 25.0 0.0 3.1 2 1 1 3 3 3 1 HEAT repeats Cnd1 PF12717.7 EPE36798.1 - 6.9e-07 29.4 0.1 9.7e-05 22.5 0.0 2.3 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 EPE36798.1 - 1.2e-06 28.2 0.0 1.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPE36798.1 - 1.3e-05 24.6 0.0 2.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 EPE36798.1 - 4.3e-05 23.9 0.3 0.024 15.1 0.6 3.9 3 1 1 4 4 4 1 HEAT-like repeat CLASP_N PF12348.8 EPE36798.1 - 0.022 14.4 0.0 1.7 8.2 0.0 2.4 1 1 1 2 2 2 0 CLASP N terminal PHD PF00628.29 EPE36799.1 - 0.0012 18.7 5.5 0.0035 17.2 5.5 1.9 1 1 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 EPE36799.1 - 0.0016 18.3 2.1 0.0032 17.4 2.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 C1_1 PF00130.22 EPE36799.1 - 0.042 13.7 2.3 0.095 12.6 2.3 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 EPE36799.1 - 0.045 13.9 3.0 0.091 12.9 2.3 1.9 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EPE36799.1 - 0.65 10.3 7.1 2.3 8.6 6.8 2.1 1 1 0 1 1 1 0 PHD-like zinc-binding domain Zf_RING PF16744.5 EPE36799.1 - 1.9 8.6 5.2 5.9 7.1 3.9 2.2 2 0 0 2 2 2 0 KIAA1045 RING finger LPP20 PF02169.16 EPE36799.1 - 3.9 7.9 7.0 6.2 7.2 0.3 3.2 2 1 1 3 3 3 0 LPP20 lipoprotein Fringe PF02434.16 EPE36800.1 - 9.2e-12 44.9 0.5 5.5e-10 39.1 0.0 2.6 3 0 0 3 3 3 2 Fringe-like DUF604 PF04646.12 EPE36800.1 - 8.4e-09 35.2 0.1 2e-08 34.0 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF604 DUF815 PF05673.13 EPE36800.1 - 0.091 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) BRO1 PF03097.18 EPE36801.1 - 1.6e-128 428.8 0.1 7.9e-128 426.6 0.0 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EPE36801.1 - 1.4e-84 283.9 14.0 1.4e-84 283.9 14.0 1.6 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF1699 PF08004.11 EPE36801.1 - 0.16 11.7 0.1 0.48 10.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) CAP_N PF01213.19 EPE36801.1 - 0.68 9.4 4.9 1.5 8.2 4.9 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CN_hydrolase PF00795.22 EPE36802.1 - 5.6e-37 127.5 0.0 8.3e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EPE36802.1 - 2.6e-14 52.9 0.0 1.5e-13 50.4 0.0 2.2 1 1 0 1 1 1 1 NAD synthase DUF4987 PF16377.5 EPE36802.1 - 0.24 11.6 1.5 15 5.8 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function zf-C2H2 PF00096.26 EPE36803.1 - 0.0016 18.7 16.9 0.021 15.3 1.0 4.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPE36803.1 - 0.063 13.7 0.4 0.063 13.7 0.4 3.4 5 0 0 5 5 5 0 Zinc-finger double domain zf-CHCC PF10276.9 EPE36803.1 - 0.52 10.4 5.3 10 6.3 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-BED PF02892.15 EPE36803.1 - 6.1 7.0 14.9 0.79 9.8 0.8 3.8 3 1 0 3 3 3 0 BED zinc finger DSPc PF00782.20 EPE36804.1 - 2.6e-24 85.5 0.0 3.7e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EPE36804.1 - 0.053 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EPE36804.1 - 0.19 11.3 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Vfa1 PF08432.10 EPE36805.1 - 1.5e-58 198.1 25.5 1.7e-58 197.9 25.5 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Dynactin_p62 PF05502.13 EPE36805.1 - 6.1e-05 22.0 7.6 7.2e-05 21.8 7.6 1.1 1 0 0 1 1 1 1 Dynactin p62 family CDC45 PF02724.14 EPE36805.1 - 0.0029 16.0 14.5 0.003 16.0 14.5 1.0 1 0 0 1 1 1 1 CDC45-like protein SpoIIIAH PF12685.7 EPE36805.1 - 0.02 14.7 11.7 0.024 14.5 11.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein SET PF00856.28 EPE36805.1 - 0.023 15.1 2.5 0.027 14.9 2.5 1.1 1 0 0 1 1 1 0 SET domain MCM_bind PF09739.9 EPE36805.1 - 0.05 12.1 8.8 0.049 12.1 8.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor FGF-BP1 PF06473.12 EPE36805.1 - 0.055 13.3 15.2 0.065 13.1 15.2 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) PADR1 PF08063.12 EPE36805.1 - 0.098 12.5 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 PADR1 (NUC008) domain SRP-alpha_N PF04086.13 EPE36805.1 - 0.13 12.2 20.7 0.17 11.8 20.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Borrelia_P83 PF05262.11 EPE36805.1 - 0.13 10.7 22.1 0.13 10.7 22.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DDHD PF02862.17 EPE36805.1 - 0.14 12.3 5.2 0.15 12.2 5.2 1.2 1 0 0 1 1 1 0 DDHD domain DUF4820 PF16091.5 EPE36805.1 - 0.2 11.0 8.0 0.35 10.2 8.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF913 PF06025.12 EPE36805.1 - 0.2 10.6 6.8 0.23 10.4 6.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Atrophin-1 PF03154.15 EPE36805.1 - 0.23 9.7 22.9 0.33 9.2 22.9 1.2 1 0 0 1 1 1 0 Atrophin-1 family PBP_sp32 PF07222.12 EPE36805.1 - 0.24 10.8 9.7 0.36 10.2 9.7 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Astro_capsid_p PF12226.8 EPE36805.1 - 0.24 10.5 8.8 0.31 10.1 8.8 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF4778 PF16008.5 EPE36805.1 - 0.26 11.3 8.9 0.33 11.0 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) SAPS PF04499.15 EPE36805.1 - 0.29 9.9 9.3 0.28 9.9 9.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF908 PF06012.12 EPE36805.1 - 0.35 10.2 3.0 0.45 9.9 3.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) U79_P34 PF03064.16 EPE36805.1 - 0.41 10.0 20.3 0.5 9.7 20.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Tim54 PF11711.8 EPE36805.1 - 0.57 8.9 15.4 0.79 8.4 15.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM60A PF15396.6 EPE36805.1 - 0.6 10.1 14.2 0.9 9.5 14.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A SLC12 PF03522.15 EPE36805.1 - 0.69 8.9 11.3 0.77 8.7 11.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIP PF07454.11 EPE36805.1 - 0.76 9.2 14.9 0.96 8.8 14.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PhyH PF05721.13 EPE36805.1 - 0.78 10.0 4.2 1 9.6 4.2 1.2 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) PPL5 PF18168.1 EPE36805.1 - 0.82 8.9 10.6 0.97 8.7 10.6 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF3438 PF11920.8 EPE36805.1 - 1.1 8.5 8.7 1.2 8.3 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) Serinc PF03348.15 EPE36805.1 - 1.4 7.8 3.3 1.5 7.7 3.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.6 EPE36805.1 - 1.4 7.2 4.6 1.4 7.2 4.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 XRN_M PF17846.1 EPE36805.1 - 1.4 7.7 12.4 1.8 7.5 12.4 1.1 1 0 0 1 1 1 0 Xrn1 helical domain RR_TM4-6 PF06459.12 EPE36805.1 - 1.7 8.4 24.5 2.2 8.0 24.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UPF0242 PF06785.11 EPE36805.1 - 2.3 8.3 16.8 2.9 8.0 16.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ALMT PF11744.8 EPE36805.1 - 2.4 6.9 9.5 2.8 6.7 9.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4407 PF14362.6 EPE36805.1 - 3 7.1 9.3 3.6 6.8 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hid1 PF12722.7 EPE36805.1 - 3.1 5.8 11.4 3.3 5.7 11.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RRN3 PF05327.11 EPE36805.1 - 3.1 6.2 12.5 3.4 6.1 12.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ATP11 PF06644.11 EPE36805.1 - 5.1 6.8 20.5 6.4 6.5 20.5 1.1 1 0 0 1 1 1 0 ATP11 protein DNA_pol_phi PF04931.13 EPE36805.1 - 5.5 5.0 19.7 7.2 4.6 19.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi NPR3 PF03666.13 EPE36805.1 - 5.7 5.6 16.9 6.5 5.4 16.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 EPE36805.1 - 6 6.0 9.0 7 5.8 9.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 EPE36805.1 - 7.2 4.4 13.4 8.4 4.2 13.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PA26 PF04636.13 EPE36805.1 - 7.5 5.3 9.8 8.3 5.2 9.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF2151 PF10221.9 EPE36805.1 - 8.6 4.8 17.2 10 4.6 17.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Presenilin PF01080.17 EPE36805.1 - 9.7 4.8 16.5 12 4.6 16.5 1.1 1 0 0 1 1 1 0 Presenilin Lyase_1 PF00206.20 EPE36806.1 - 4.5e-90 302.2 0.0 6.1e-90 301.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EPE36806.1 - 8e-23 81.0 0.0 1.9e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Ufd2P_core PF10408.9 EPE36807.1 - 3.7e-217 722.9 11.2 4.6e-217 722.5 11.2 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EPE36807.1 - 1.3e-25 89.3 2.5 2.8e-25 88.3 1.7 2.0 2 0 0 2 2 2 1 U-box domain DUF1977 PF09320.11 EPE36808.1 - 2.2e-25 89.0 1.4 3.4e-25 88.3 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 EPE36808.1 - 5.6e-20 71.2 0.1 1e-19 70.4 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Aim19 PF10315.9 EPE36809.1 - 2.2e-05 24.7 0.1 3.5e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Ima1_N PF09779.9 EPE36810.1 - 1.9e-25 90.3 0.3 3.5e-25 89.4 0.3 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain Alg14 PF08660.11 EPE36811.1 - 2.4e-53 180.6 0.2 7.5e-53 179.0 0.2 1.7 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TAS2R PF05296.13 EPE36811.1 - 0.00052 19.2 0.8 0.00052 19.2 0.8 1.6 2 0 0 2 2 2 1 Taste receptor protein (TAS2R) MRP-S25 PF13741.6 EPE36812.1 - 1.4e-69 234.2 4.8 8.8e-61 205.4 1.3 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EPE36812.1 - 1.8e-06 28.2 1.0 8.3e-06 26.1 1.0 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 PPR_2 PF13041.6 EPE36813.1 - 4.9e-15 55.5 4.6 2.9e-05 24.2 0.2 5.5 3 1 3 6 6 6 4 PPR repeat family PPR PF01535.20 EPE36813.1 - 4.2e-09 36.0 8.9 3.3e-05 23.9 0.1 5.5 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 EPE36813.1 - 0.00017 21.6 0.7 0.072 13.2 0.0 4.0 4 1 1 5 5 5 1 Pentatricopeptide repeat domain PPR_long PF17177.4 EPE36813.1 - 0.00021 20.7 1.1 0.068 12.5 0.2 2.3 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EPE36813.1 - 0.0033 17.1 5.4 0.01 15.5 0.0 3.3 3 1 0 3 3 3 1 PPR repeat Lentiviral_Tat PF02998.14 EPE36813.1 - 0.66 10.0 3.8 1.2 9.2 0.2 2.8 2 0 0 2 2 2 0 Lentiviral Tat protein PNK3P PF08645.11 EPE36814.1 - 9.2e-56 188.0 0.0 1.3e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EPE36814.1 - 7.5e-24 84.5 0.1 4.3e-12 46.4 0.1 2.4 1 1 1 2 2 2 2 AAA domain KTI12 PF08433.10 EPE36814.1 - 0.2 11.1 2.4 8.4 5.8 0.3 2.3 1 1 1 2 2 2 0 Chromatin associated protein KTI12 Pkinase PF00069.25 EPE36816.1 - 1e-06 28.4 0.0 0.00091 18.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Rtt106 PF08512.12 EPE36817.1 - 3.2e-31 107.6 0.0 5.4e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 EPE36817.1 - 0.001 19.1 0.1 0.0075 16.3 0.1 2.4 2 1 0 2 2 2 1 Pleckstrin homology domain MNSV_P7B PF06692.11 EPE36818.1 - 0.13 12.3 0.2 0.35 10.9 0.1 1.8 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein CHD5 PF04420.14 EPE36819.1 - 7.3e-58 194.9 0.6 9.4e-58 194.6 0.6 1.1 1 0 0 1 1 1 1 CHD5-like protein PPTA PF01239.22 EPE36820.1 - 6.9e-09 35.2 7.6 7.5e-05 22.3 0.5 3.5 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat DUF4296 PF14129.6 EPE36820.1 - 0.029 15.0 0.0 5.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) Ecm33 PF12454.8 EPE36821.1 - 8.8e-09 35.4 3.2 2.8e-08 33.7 2.3 2.5 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 EPE36821.1 - 1.3e-08 35.0 0.3 0.0056 16.8 0.0 4.1 1 1 3 4 4 4 2 Receptor L domain H_lectin PF09458.10 EPE36821.1 - 0.054 13.7 2.0 0.43 10.8 0.7 2.6 2 0 0 2 2 2 0 H-type lectin domain VWA_CoxE PF05762.14 EPE36821.1 - 0.2 11.0 0.8 0.55 9.6 0.1 1.8 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein AcetylCoA_hydro PF02550.15 EPE36822.1 - 1.9e-47 161.8 0.0 2.9e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 EPE36822.1 - 1.6e-41 141.8 0.0 2.6e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.23 EPE36822.1 - 0.023 14.1 0.0 0.07 12.5 0.0 1.8 2 0 0 2 2 2 0 Coenzyme A transferase Ndc1_Nup PF09531.10 EPE36823.1 - 1.9e-188 628.0 0.7 2.2e-188 627.8 0.7 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 EPE36824.1 - 4.1e-25 88.1 4.4 4.1e-25 88.1 4.4 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EPE36824.1 - 7.8e-16 57.8 0.6 7.8e-16 57.8 0.6 2.2 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.25 EPE36824.1 - 0.0001 22.0 10.4 0.005 16.5 10.4 2.5 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 EPE36824.1 - 0.012 15.4 5.7 1.6 8.5 4.4 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Nre_C PF04895.12 EPE36824.1 - 0.018 15.0 3.1 0.022 14.6 0.1 2.4 2 1 1 3 3 3 0 Archaeal Nre, C-terminal ARA70 PF12489.8 EPE36824.1 - 0.15 12.2 11.3 0.069 13.3 8.0 2.0 2 0 0 2 2 2 0 Nuclear coactivator SKA1 PF07160.12 EPE36824.1 - 0.5 10.2 9.0 0.97 9.2 0.1 2.2 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Prominin PF05478.11 EPE36824.1 - 0.54 8.2 7.7 2.2 6.2 7.7 1.9 1 1 0 1 1 1 0 Prominin DUF883 PF05957.13 EPE36824.1 - 1.8 9.3 9.5 0.79 10.4 0.2 3.0 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.13 EPE36824.1 - 2.2 7.4 6.6 3.5 6.8 4.6 1.9 1 1 1 2 2 2 0 TMPIT-like protein Synaptobrevin PF00957.21 EPE36824.1 - 5.7 6.8 5.9 1.6 8.6 1.3 2.4 3 1 0 3 3 3 0 Synaptobrevin GRAB PF10375.9 EPE36825.1 - 4.4e-09 35.9 0.1 8.6e-09 34.9 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain DUF1664 PF07889.12 EPE36825.1 - 0.013 15.5 25.6 0.23 11.5 7.5 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Filament PF00038.21 EPE36825.1 - 0.039 13.5 55.9 0.76 9.3 35.5 3.1 1 1 1 2 2 2 0 Intermediate filament protein Golgin_A5 PF09787.9 EPE36825.1 - 0.13 11.7 58.3 0.9 9.0 9.3 3.5 1 1 2 3 3 3 0 Golgin subfamily A member 5 Tropomyosin PF00261.20 EPE36825.1 - 0.35 10.2 65.6 0.0059 16.0 41.3 2.6 1 1 1 2 2 2 0 Tropomyosin Phage_holin_7_1 PF16081.5 EPE36825.1 - 0.76 10.0 4.2 13 5.9 0.3 2.9 2 1 1 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family CENP-F_leu_zip PF10473.9 EPE36825.1 - 1.1 9.2 58.4 0.11 12.5 21.5 4.0 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RPW8 PF05659.11 EPE36825.1 - 1.5 8.5 11.6 1.7 8.3 0.5 3.8 3 1 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TPR_MLP1_2 PF07926.12 EPE36825.1 - 3.4 7.7 68.3 2.4 8.3 18.1 5.0 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein MAD PF05557.13 EPE36825.1 - 4 5.7 61.3 11 4.3 20.1 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein Spc7 PF08317.11 EPE36825.1 - 4.7 6.0 57.6 4.8 6.0 26.4 3.4 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF3584 PF12128.8 EPE36825.1 - 5.2 4.5 57.9 0.53 7.7 38.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1722 PF08349.11 EPE36825.1 - 7.4 6.9 8.5 1.4 9.2 0.3 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1722) TMPIT PF07851.13 EPE36825.1 - 7.6 5.7 35.3 0.35 10.1 3.7 3.6 2 1 1 3 3 3 0 TMPIT-like protein Catalase PF00199.19 EPE36826.1 - 1.6e-06 27.5 0.3 0.0086 15.2 0.0 2.2 2 0 0 2 2 2 2 Catalase PP2C_C PF07830.13 EPE36826.1 - 0.15 12.5 0.0 3.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Gag_spuma PF03276.14 EPE36827.1 - 1.9 6.8 6.5 2.4 6.5 6.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein MHYT PF03707.16 EPE36828.1 - 4.7e-10 39.5 22.4 1.7e-06 28.1 2.4 4.8 4 1 0 4 4 4 3 Bacterial signalling protein N terminal repeat G-patch PF01585.23 EPE36829.1 - 1.2e-12 47.5 1.1 2.2e-12 46.7 1.1 1.4 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EPE36829.1 - 3.5e-05 23.5 0.0 7.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rrn6 PF10214.9 EPE36829.1 - 1.6 7.1 7.5 3.2 6.1 7.6 1.4 1 1 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor AMP-binding PF00501.28 EPE36830.1 - 5.8e-87 292.0 0.0 7.3e-87 291.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPE36830.1 - 1.4e-18 67.6 0.2 2e-17 64.0 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EPE36830.1 - 0.00039 19.4 0.0 0.0019 17.2 0.0 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 EPE36830.1 - 0.00074 19.6 0.0 0.0018 18.4 0.0 1.6 1 0 0 1 1 1 1 RTX C-terminal domain zf-RING_2 PF13639.6 EPE36831.1 - 1.7e-06 28.3 6.9 1.7e-06 28.3 6.9 1.8 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.17 EPE36831.1 - 1.7e-05 24.4 0.2 3.7e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 SWIM zinc finger Prok-RING_1 PF14446.6 EPE36831.1 - 3.7e-05 23.6 2.3 3.7e-05 23.6 2.3 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 EPE36831.1 - 0.00022 21.2 2.0 0.00022 21.2 2.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EPE36831.1 - 0.0036 17.4 4.9 0.0036 17.4 4.9 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain zf-rbx1 PF12678.7 EPE36831.1 - 0.027 14.8 4.6 0.027 14.8 4.6 1.8 2 0 0 2 2 1 0 RING-H2 zinc finger domain PHD PF00628.29 EPE36831.1 - 0.07 13.0 6.9 0.15 12.0 6.9 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 EPE36831.1 - 0.085 12.7 7.2 0.18 11.6 7.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Stc1 PF12898.7 EPE36831.1 - 0.77 10.3 4.8 0.23 12.1 1.5 1.8 2 0 0 2 2 2 0 Stc1 domain RINGv PF12906.7 EPE36831.1 - 2.3 8.4 8.2 5.7 7.1 8.2 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.6 EPE36831.1 - 2.8 7.8 8.2 0.78 9.6 4.0 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPE36831.1 - 4.5 7.2 7.1 20 5.2 7.1 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2408 PF10303.9 EPE36833.1 - 2.8e-38 131.5 7.7 2.2e-26 93.0 1.0 4.7 3 2 1 4 4 4 3 Protein of unknown function (DUF2408) Pox_J1 PF03338.15 EPE36833.1 - 0.0029 17.5 2.7 0.89 9.4 0.1 3.6 4 0 0 4 4 4 1 Poxvirus J1 protein Laminin_II PF06009.12 EPE36833.1 - 0.024 14.7 6.7 0.42 10.6 0.3 2.8 1 1 1 2 2 2 0 Laminin Domain II DUF2920 PF11144.8 EPE36833.1 - 0.09 11.9 0.1 12 5.0 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2920) Nup54 PF13874.6 EPE36833.1 - 0.12 12.5 2.7 0.4 10.8 2.7 1.9 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Cytochrom_B562 PF07361.11 EPE36833.1 - 0.15 12.7 0.8 4.6 8.0 1.0 2.5 1 1 0 1 1 1 0 Cytochrome b562 SKA2 PF16740.5 EPE36833.1 - 0.7 9.7 6.1 5.1 6.9 0.3 3.0 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 TBCC_N PF16752.5 EPE36833.1 - 1.1 9.7 5.8 0.33 11.4 0.3 2.7 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain Ribosomal_60s PF00428.19 EPE36834.1 - 1.2e-26 93.1 8.6 1.4e-26 92.9 8.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein YCII PF03795.14 EPE36835.1 - 3e-06 27.5 0.0 5e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 YCII-related domain HMG_box PF00505.19 EPE36836.1 - 2.6e-13 50.2 0.2 5.2e-13 49.2 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EPE36836.1 - 8.1e-09 36.0 0.3 2e-08 34.7 0.3 1.6 1 0 0 1 1 1 1 HMG-box domain Methyltransf_1N PF02870.15 EPE36836.1 - 0.06 14.2 0.0 0.13 13.1 0.0 1.6 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Cut8 PF08559.10 EPE36838.1 - 1.1e-81 274.0 0.0 1.4e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein OTCace PF00185.24 EPE36839.1 - 5.1e-44 150.1 0.0 7.7e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EPE36839.1 - 1.7e-43 148.2 0.6 2.9e-43 147.4 0.6 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Porin_3 PF01459.22 EPE36840.1 - 7.9e-64 215.7 11.2 1.1e-61 208.7 11.2 2.0 1 1 0 1 1 1 1 Eukaryotic porin TetR_C_24 PF17932.1 EPE36841.1 - 0.078 13.3 0.9 0.12 12.6 0.9 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Viral_DNA_bp PF00747.17 EPE36841.1 - 0.098 9.8 0.3 0.12 9.5 0.3 1.0 1 0 0 1 1 1 0 ssDNA binding protein zf-CCHC PF00098.23 EPE36841.1 - 4.7 7.5 7.8 0.86 9.8 3.6 2.0 2 0 0 2 2 2 0 Zinc knuckle Snurportin1 PF11538.8 EPE36842.1 - 1.9 8.8 5.4 4 7.7 5.4 1.6 1 0 0 1 1 1 0 Snurportin1 Pex19 PF04614.12 EPE36843.1 - 1.4e-75 254.2 14.7 1.8e-75 253.8 14.7 1.1 1 0 0 1 1 1 1 Pex19 protein family ATG_C PF09333.11 EPE36843.1 - 0.022 15.1 1.1 0.51 10.7 0.0 2.7 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain ABC_tran_Xtn PF12848.7 EPE36843.1 - 0.3 11.2 4.3 1.2 9.2 0.3 2.9 3 0 0 3 3 3 0 ABC transporter FliE PF02049.18 EPE36843.1 - 1.6 8.9 13.4 0.072 13.2 2.0 3.6 3 2 1 4 4 4 0 Flagellar hook-basal body complex protein FliE GET2 PF08690.10 EPE36843.1 - 8 6.0 25.1 0.25 11.0 8.8 2.2 1 1 1 2 2 2 0 GET complex subunit GET2 UQ_con PF00179.26 EPE36844.1 - 2e-49 166.8 0.0 2.3e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPE36844.1 - 0.00011 21.8 0.0 0.00015 21.5 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EPE36844.1 - 0.029 14.7 0.7 0.055 13.8 0.7 1.7 1 1 0 1 1 1 0 RWD domain Asn_synthase PF00733.21 EPE36845.1 - 3.5e-92 309.8 1.1 1.3e-55 189.5 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EPE36845.1 - 3.9e-37 126.9 0.0 6.8e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EPE36845.1 - 1.5e-28 99.6 0.0 3.9e-28 98.3 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EPE36845.1 - 2.6e-07 30.3 0.0 5.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EPE36845.1 - 0.00011 21.4 0.1 0.0012 18.1 0.1 2.0 1 1 0 1 1 1 1 NAD synthase QueC PF06508.13 EPE36845.1 - 0.17 11.3 0.0 0.63 9.5 0.0 1.8 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Peptidase_M24 PF00557.24 EPE36847.1 - 2.2e-41 141.9 0.0 2.9e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 PGA2 PF07543.12 EPE36847.1 - 2 8.4 6.5 4.4 7.3 6.5 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 Cnd2 PF05786.14 EPE36847.1 - 3.7 6.1 8.1 5.7 5.5 8.1 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 CDC45 PF02724.14 EPE36847.1 - 9.8 4.3 6.1 14 3.8 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DnaJ PF00226.31 EPE36848.1 - 2.7e-20 72.2 0.3 3.9e-20 71.7 0.3 1.2 1 0 0 1 1 1 1 DnaJ domain adh_short_C2 PF13561.6 EPE36849.1 - 2e-33 115.9 0.1 9.2e-33 113.7 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE36849.1 - 3.1e-32 111.6 0.1 4.7e-32 111.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE36849.1 - 7.5e-10 39.0 0.5 1.3e-09 38.3 0.5 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 EPE36849.1 - 0.015 15.3 0.2 0.029 14.5 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EPE36849.1 - 0.046 14.0 0.2 0.081 13.2 0.2 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PSP PF04046.16 EPE36849.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 PSP Med13_N PF11597.8 EPE36849.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Polysacc_synt_2 PF02719.15 EPE36849.1 - 0.14 11.3 0.1 0.25 10.5 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EPE36849.1 - 0.15 11.1 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SRAP PF02586.14 EPE36849.1 - 0.17 11.4 0.0 0.53 9.8 0.0 1.6 1 1 0 1 1 1 0 SOS response associated peptidase (SRAP) SKG6 PF08693.10 EPE36850.1 - 0.00017 20.9 0.1 0.0003 20.1 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF3611 PF12263.8 EPE36850.1 - 0.00078 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) Rax2 PF12768.7 EPE36850.1 - 0.026 14.0 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity VSP PF03302.13 EPE36850.1 - 0.092 11.6 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein AA_permease PF00324.21 EPE36851.1 - 6.3e-121 404.3 43.5 7.6e-121 404.0 43.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPE36851.1 - 1.4e-36 126.2 45.8 1.8e-36 125.9 45.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3328 PF11807.8 EPE36852.1 - 6.2e-25 88.3 1.4 1e-24 87.6 1.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) MDD_C PF18376.1 EPE36853.1 - 6.8e-65 218.3 0.1 1.1e-64 217.7 0.1 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EPE36853.1 - 1.8e-09 37.7 1.5 5.1e-09 36.3 0.8 2.2 3 0 0 3 3 3 1 GHMP kinases N terminal domain Cyto_heme_lyase PF01265.17 EPE36854.1 - 3.6e-43 148.2 9.1 2.8e-42 145.3 9.1 2.2 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF647 PF04884.14 EPE36855.1 - 3.6e-109 364.0 0.5 4.4e-109 363.7 0.5 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Imm40 PF15569.6 EPE36855.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 40 DENN PF02141.21 EPE36856.1 - 6.4e-60 202.3 0.1 1.1e-59 201.6 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 EPE36856.1 - 5.7e-15 55.0 0.4 2.5e-14 53.0 0.3 2.2 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.18 EPE36856.1 - 6.7e-13 49.2 1.1 1.9e-12 47.7 0.0 2.4 3 0 0 3 3 3 1 uDENN domain C1_2 PF03107.16 EPE36856.1 - 0.014 15.7 9.0 0.028 14.8 9.0 1.4 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 EPE36856.1 - 0.018 14.9 6.9 0.038 13.9 6.9 1.5 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 EPE36856.1 - 0.039 13.9 7.9 0.068 13.1 7.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 EPE36856.1 - 0.11 12.6 3.4 0.21 11.7 3.4 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger SPA PF08616.10 EPE36856.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis FDF PF09532.10 EPE36856.1 - 2.4 9.1 0.0 2.4 9.1 0.0 2.8 3 0 0 3 3 3 0 FDF domain rRNA_proc-arch PF13234.6 EPE36857.1 - 3.9e-90 302.5 0.3 1e-89 301.1 0.0 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 EPE36857.1 - 8.6e-51 171.9 1.8 8.6e-51 171.9 1.8 2.3 3 0 0 3 3 3 1 DSHCT (NUC185) domain DEAD PF00270.29 EPE36857.1 - 6.3e-19 68.4 0.0 1.7e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE36857.1 - 5.4e-06 26.7 0.1 3.8e-05 24.0 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPE36857.1 - 1.2e-05 25.4 0.0 4.7e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EPE36857.1 - 0.031 13.3 0.0 0.071 12.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 EPE36857.1 - 0.052 13.5 0.0 0.17 11.7 0.0 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Prp19 PF08606.11 EPE36857.1 - 0.068 13.2 0.6 5.5 7.1 0.0 2.7 2 0 0 2 2 2 0 Prp19/Pso4-like AAA_22 PF13401.6 EPE36857.1 - 0.16 12.2 0.0 0.79 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Trypan_PARP PF05887.11 EPE36857.1 - 3.1 7.8 9.6 7.3 6.6 9.6 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) COX7C PF02935.16 EPE36858.1 - 1.7e-25 89.0 3.5 2e-25 88.8 3.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Med18 PF09637.10 EPE36859.1 - 1.6e-46 159.2 0.0 1.9e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Med18 protein HsbA PF12296.8 EPE36860.1 - 7.8e-35 119.9 16.1 1.1e-34 119.4 16.1 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Gp-FAR-1 PF05823.12 EPE36860.1 - 0.0054 17.1 0.4 0.04 14.3 0.2 2.2 1 1 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1451 PF07295.11 EPE36860.1 - 0.12 12.4 0.7 0.18 11.8 0.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain Phage_Coat_B PF05356.11 EPE36860.1 - 0.51 10.3 3.1 9.2 6.3 0.1 2.7 1 1 1 2 2 2 0 Phage Coat protein B S36_mt PF10937.8 EPE36861.1 - 3.2e-38 131.8 1.0 6.1e-38 131.0 1.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial GMC_oxred_N PF00732.19 EPE36862.1 - 1.6e-32 113.1 0.0 7.9e-25 87.8 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EPE36862.1 - 6.1e-31 107.9 0.0 1.3e-30 106.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EPE36862.1 - 0.00013 21.2 0.1 0.0056 15.8 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EPE36862.1 - 0.01 15.1 0.3 0.23 10.7 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPE36862.1 - 0.017 14.7 0.8 0.28 10.7 0.4 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPE36862.1 - 0.019 14.2 0.0 0.68 9.1 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE36862.1 - 0.061 13.6 0.7 0.14 12.4 0.7 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPE36862.1 - 0.09 11.8 0.1 0.26 10.3 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein HD PF01966.22 EPE36863.1 - 6.9e-08 32.7 0.0 9.7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 HD domain Pyr_redox_3 PF13738.6 EPE36864.1 - 1.3e-15 57.5 0.0 6.3e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPE36864.1 - 9.3e-13 48.1 0.0 1e-10 41.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EPE36864.1 - 1.5e-12 46.7 0.0 5.7e-09 34.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EPE36864.1 - 6.9e-12 45.2 0.1 4.8e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EPE36864.1 - 1.1e-05 25.5 0.1 4.2e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EPE36864.1 - 0.00017 20.9 0.0 0.0003 20.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EPE36864.1 - 0.00092 18.9 0.0 1.3 8.6 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EPE36864.1 - 0.0014 17.4 0.1 1 8.0 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 EPE36864.1 - 0.11 12.5 0.1 0.5 10.3 0.0 2.2 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EPE36864.1 - 0.2 12.2 0.6 18 6.0 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M14 PF00246.24 EPE36865.1 - 1.9e-41 142.8 0.3 2.7e-41 142.3 0.3 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF1798 PF08807.10 EPE36866.1 - 0.038 14.1 0.3 0.058 13.5 0.3 1.4 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) GPW_gp25 PF04965.14 EPE36866.1 - 0.078 12.8 0.0 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 Gene 25-like lysozyme TPR_14 PF13428.6 EPE36868.1 - 0.00067 20.3 0.1 0.081 13.8 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Actin PF00022.19 EPE36869.1 - 3.3e-05 22.7 0.1 5.4e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Actin Myc_N PF01056.18 EPE36876.1 - 1.2 9.0 6.6 3.2 7.6 6.6 1.7 1 1 0 1 1 1 0 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.8 EPE36876.1 - 8 6.6 20.1 1.4 9.2 15.1 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 ALS_ss_C PF10369.9 EPE36877.1 - 1.1e-14 54.4 0.0 1.1e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EPE36877.1 - 4.9e-14 51.8 0.1 1e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EPE36877.1 - 3.7e-08 33.1 0.1 7.5e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 EPE36877.1 - 0.1 12.6 0.0 23 5.1 0.0 2.5 2 0 0 2 2 2 0 ACT domain KH_1 PF00013.29 EPE36878.1 - 3.7e-09 36.3 0.0 1.3e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 KH domain S_100 PF01023.19 EPE36878.1 - 0.15 11.8 0.3 18 5.1 0.0 2.3 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain SET PF00856.28 EPE36879.1 - 1.4e-13 51.6 0.0 2.9e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 SET domain DUF974 PF06159.13 EPE36880.1 - 2.3e-78 263.4 0.0 2.8e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DUF3712 PF12505.8 EPE36881.1 - 2.6e-05 24.5 0.1 0.00014 22.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 EPE36881.1 - 0.00044 20.7 2.5 3.4 8.3 0.0 5.2 6 1 0 6 6 6 2 Late embryogenesis abundant protein Bcr-Abl_Oligo PF09036.10 EPE36882.1 - 0.64 10.1 4.5 2.3 8.3 0.4 2.7 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain RGS PF00615.19 EPE36887.1 - 1.5e-09 38.1 0.0 2.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Aa_trans PF01490.18 EPE36889.1 - 6.7e-20 71.2 34.4 9.3e-20 70.7 34.4 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATPase_2 PF01637.18 EPE36890.1 - 6.6e-07 29.5 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 EPE36890.1 - 2.1e-05 24.5 0.0 5.5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 EPE36890.1 - 0.0012 19.3 0.0 0.012 16.1 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ank_2 PF12796.7 EPE36890.1 - 0.0017 18.9 0.0 0.14 12.7 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) AAA_22 PF13401.6 EPE36890.1 - 0.011 16.1 0.0 0.048 13.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF676 PF05057.14 EPE36890.1 - 0.026 14.1 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Ank_4 PF13637.6 EPE36890.1 - 0.026 15.1 0.1 0.6 10.8 0.0 3.3 4 1 0 4 4 3 0 Ankyrin repeats (many copies) AAA_29 PF13555.6 EPE36890.1 - 0.055 13.2 0.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain HAUS4 PF14735.6 EPE36890.1 - 0.06 13.0 3.2 0.53 10.0 0.1 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 YolD PF08863.10 EPE36890.1 - 0.075 13.1 0.2 0.22 11.6 0.2 1.8 1 0 0 1 1 1 0 YolD-like protein AAA_18 PF13238.6 EPE36890.1 - 0.078 13.5 0.1 0.22 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EPE36890.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EPE36890.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EPE36890.1 - 0.18 10.9 0.0 0.48 9.6 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain MIP PF00230.20 EPE36892.1 - 8.8e-47 159.7 21.7 1.1e-46 159.4 21.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein TMEM208_SND2 PF05620.11 EPE36892.1 - 0.044 13.6 0.2 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Steroid_dh PF02544.16 EPE36893.1 - 3.9e-19 69.1 0.2 3.4e-18 66.1 0.0 2.3 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EPE36893.1 - 4.4e-05 23.1 0.1 7.4e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) CTP_transf_like PF01467.26 EPE36894.1 - 0.00013 22.2 0.0 0.00069 19.8 0.0 2.3 1 1 0 1 1 1 1 Cytidylyltransferase-like ATP-grasp_4 PF13535.6 EPE36896.1 - 4e-13 49.3 0.0 2.1e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_N PF18130.1 EPE36896.1 - 1.6e-10 41.4 0.1 3.2e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp N-terminal domain Dala_Dala_lig_C PF07478.13 EPE36896.1 - 4e-08 33.0 0.0 8.6e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EPE36896.1 - 5.5e-06 26.5 0.0 3.8e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EPE36896.1 - 4.6e-05 23.3 0.0 8.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 EPE36896.1 - 0.00027 20.5 0.0 0.00063 19.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 EPE36896.1 - 0.031 14.0 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 EPE36896.1 - 0.13 11.8 0.0 0.84 9.2 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain WD40 PF00400.32 EPE36897.1 - 1.4e-28 98.5 13.1 5.7e-08 33.3 0.1 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE36897.1 - 8.4e-11 42.0 1.5 0.11 12.8 0.0 5.2 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain DUF3086 PF11285.8 EPE36898.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) adh_short PF00106.25 EPE36899.1 - 3.1e-28 98.6 0.1 4.5e-28 98.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE36899.1 - 9.3e-22 77.7 0.1 1.1e-21 77.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE36899.1 - 1.6e-06 28.2 0.1 2e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 KR domain AIRC PF00731.20 EPE36899.1 - 0.015 14.8 0.1 0.39 10.3 0.0 2.6 2 1 1 3 3 3 0 AIR carboxylase DUF1776 PF08643.10 EPE36899.1 - 0.078 12.3 0.0 1.9 7.8 0.0 2.1 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Endonuc-FokI_C PF09254.11 EPE36900.1 - 0.13 11.5 0.5 0.21 10.8 0.5 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Glyco_hydro_32N PF00251.20 EPE36901.1 - 0.00095 18.8 0.1 0.0025 17.5 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.14 EPE36901.1 - 0.0048 16.3 2.5 0.0081 15.5 2.5 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 AAA PF00004.29 EPE36902.1 - 2.2e-06 28.1 0.0 4.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 EPE36902.1 - 0.0069 16.5 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Torsin AAA_5 PF07728.14 EPE36902.1 - 0.067 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MARVEL PF01284.23 EPE36906.1 - 8e-06 25.9 10.3 5.9e-05 23.1 8.8 2.0 1 1 1 2 2 2 2 Membrane-associating domain WLM PF08325.10 EPE36908.1 - 2.2e-49 168.1 0.0 3.8e-49 167.4 0.0 1.4 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 EPE36908.1 - 0.00037 20.6 0.4 0.001 19.2 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.9 EPE36908.1 - 0.00046 20.0 2.1 0.0011 18.8 2.1 1.7 1 1 0 1 1 1 1 SprT-like family ubiquitin PF00240.23 EPE36908.1 - 0.0071 16.1 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Reprolysin_5 PF13688.6 EPE36908.1 - 0.068 13.3 0.6 0.17 12.0 0.2 1.7 1 1 1 2 2 2 0 Metallo-peptidase family M12 ER_lumen_recept PF00810.18 EPE36909.1 - 5.8e-54 182.9 10.1 9.9e-54 182.2 10.1 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EPE36909.1 - 0.017 14.9 14.3 0.28 11.0 0.5 4.2 4 1 1 5 5 5 0 PQ loop repeat Molybdopterin PF00384.22 EPE36910.1 - 1.8e-74 251.3 0.0 2.6e-72 244.2 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EPE36910.1 - 2.5e-20 72.3 0.2 7.5e-20 70.8 0.2 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 EPE36910.1 - 3.1e-18 66.2 0.0 8.3e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 EPE36910.1 - 2.8e-17 62.0 0.2 2.8e-17 62.0 0.2 2.2 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 EPE36910.1 - 2.9e-08 33.6 0.6 2.9e-08 33.6 0.6 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 EPE36910.1 - 0.035 13.8 0.0 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Lyx_isomer PF07385.12 EPE36910.1 - 0.22 10.8 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 D-lyxose isomerase TMEM208_SND2 PF05620.11 EPE36911.1 - 0.2 11.4 0.1 0.82 9.4 0.0 1.8 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF4282 PF14110.6 EPE36911.1 - 0.61 10.9 5.5 1 10.1 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) SLATT_1 PF18181.1 EPE36911.1 - 0.82 9.6 3.0 8.1 6.4 0.1 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 DDOST_48kD PF03345.14 EPE36913.1 - 5.7e-165 549.2 0.0 7e-165 548.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta RTA1 PF04479.13 EPE36914.1 - 3.8e-77 258.6 4.6 5.4e-77 258.1 4.6 1.2 1 0 0 1 1 1 1 RTA1 like protein DHHC PF01529.20 EPE36914.1 - 4.3 7.4 9.8 7.9 6.6 0.6 3.2 3 1 1 4 4 4 0 DHHC palmitoyltransferase Amidohydro_3 PF07969.11 EPE36915.1 - 6.2e-15 55.6 1.3 2.2e-08 34.0 0.1 3.2 4 0 0 4 4 4 2 Amidohydrolase family Amidohydro_1 PF01979.20 EPE36915.1 - 5.3e-13 49.0 1.3 1.2e-10 41.2 0.0 3.0 3 1 0 3 3 3 2 Amidohydrolase family MGC-24 PF05283.11 EPE36916.1 - 0.0025 18.2 0.4 0.0058 17.1 0.4 1.5 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin Asp PF00026.23 EPE36916.1 - 0.0045 16.5 0.1 0.0045 16.5 0.1 2.3 3 0 0 3 3 3 1 Eukaryotic aspartyl protease Stevor PF17410.2 EPE36916.1 - 0.023 14.3 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame TMEM51 PF15345.6 EPE36916.1 - 0.068 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF5305 PF17231.2 EPE36916.1 - 0.2 11.0 0.1 0.38 10.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) peroxidase PF00141.23 EPE36918.1 - 1.2e-26 93.8 0.1 1.7e-26 93.3 0.1 1.1 1 0 0 1 1 1 1 Peroxidase MFS_1 PF07690.16 EPE36920.1 - 1.6e-29 103.0 28.9 1.6e-29 103.0 28.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_S8 PF00082.22 EPE36922.1 - 1.2e-37 129.8 13.8 1.4e-37 129.5 13.0 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EPE36922.1 - 1.5e-22 80.0 1.3 3.7e-22 78.8 1.3 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.18 EPE36923.1 - 3.9e-120 400.4 0.1 6.8e-120 399.6 0.1 1.4 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 EPE36923.1 - 1.3e-10 41.6 0.1 3.1e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 EPE36923.1 - 8.5e-10 38.6 0.0 2.5e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 EPE36923.1 - 2.8e-05 24.8 1.5 0.0034 18.2 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF4800 PF16057.5 EPE36923.1 - 0.29 10.4 6.1 2.3 7.4 6.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4800) APH PF01636.23 EPE36924.1 - 2.7e-12 47.1 0.0 4.3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPE36924.1 - 4.8e-06 26.3 0.0 7.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EPE36924.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family YjeF_N PF03853.15 EPE36925.1 - 2.4e-34 118.7 0.0 3e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.19 EPE36926.1 - 2.2e-26 91.7 0.1 3e-26 91.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 Aa_trans PF01490.18 EPE36927.1 - 1.8e-93 313.5 17.8 2.9e-93 312.8 17.8 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EPE36927.1 - 3.5e-09 36.2 21.0 7e-09 35.2 21.0 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family ORMDL PF04061.14 EPE36927.1 - 0.0076 16.1 4.1 0.051 13.4 4.1 2.2 1 1 0 1 1 1 1 ORMDL family TrbC PF04956.13 EPE36927.1 - 8.9 6.6 15.0 17 5.7 0.1 4.8 4 0 0 4 4 4 0 TrbC/VIRB2 family Dynactin_p22 PF07426.11 EPE36928.1 - 9.1e-12 45.1 0.4 1.5e-11 44.4 0.4 1.3 1 0 0 1 1 1 1 Dynactin subunit p22 Isochorismatase PF00857.20 EPE36930.1 - 5.1e-14 52.8 0.1 1.5e-13 51.4 0.0 1.7 2 1 0 2 2 2 1 Isochorismatase family adh_short_C2 PF13561.6 EPE36931.1 - 3.7e-57 193.6 0.1 5.3e-57 193.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE36931.1 - 6.6e-41 139.9 0.1 9.3e-41 139.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE36931.1 - 7.5e-14 52.0 0.1 1.1e-13 51.5 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EPE36931.1 - 0.0033 17.3 0.1 0.03 14.2 0.2 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EPE36931.1 - 0.0044 16.5 0.0 0.053 12.9 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1752 PF08550.10 EPE36934.1 - 8.6e-09 35.1 3.8 2e-08 33.9 3.8 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DLIC PF05783.11 EPE36935.1 - 1.3e-40 139.6 0.3 3.6e-37 128.3 0.0 3.2 3 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) RRM_1 PF00076.22 EPE36936.1 - 6.7e-20 70.7 0.0 1.9e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPE36936.1 - 9.5e-05 22.4 0.0 0.00032 20.8 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif Sigma70_r1_2 PF00140.20 EPE36936.1 - 0.35 10.9 3.1 0.35 10.9 0.8 2.2 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 WD40 PF00400.32 EPE36937.1 - 0.00064 20.5 0.1 2.5 9.1 0.0 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPE36937.1 - 0.0022 18.2 0.0 5.5 7.4 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EPE36937.1 - 0.15 11.4 0.0 0.48 9.7 0.0 1.6 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal VID27 PF08553.10 EPE36937.1 - 0.16 11.0 0.3 0.49 9.4 0.0 1.9 3 0 0 3 3 3 0 VID27 C-terminal WD40-like domain Septin PF00735.18 EPE36938.1 - 1.4e-107 359.2 0.1 3.3e-107 358.0 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EPE36938.1 - 4.2e-05 23.6 0.1 0.00012 22.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EPE36938.1 - 0.0062 16.7 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EPE36938.1 - 0.022 14.7 0.4 0.022 14.7 0.4 2.7 3 1 0 3 3 3 0 RsgA GTPase Dynamin_N PF00350.23 EPE36938.1 - 0.065 13.3 7.0 2.1 8.4 0.0 3.1 2 1 1 3 3 3 0 Dynamin family Herpes_U5 PF05999.11 EPE36938.1 - 0.099 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus U5-like family AIG1 PF04548.16 EPE36938.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 AIG1 family Ribosomal_S17e PF00833.18 EPE36938.1 - 0.36 10.8 4.9 0.85 9.5 4.9 1.6 1 0 0 1 1 1 0 Ribosomal S17 EB1 PF03271.17 EPE36938.1 - 1.2 9.4 4.3 8.4 6.7 4.3 2.3 1 1 0 1 1 1 0 EB1-like C-terminal motif AAA_23 PF13476.6 EPE36938.1 - 4.6 7.7 9.8 10 6.5 5.1 2.2 2 1 0 2 2 2 0 AAA domain Helo_like_N PF17111.5 EPE36939.1 - 0.00015 21.2 0.2 0.0004 19.8 0.2 1.8 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Phage_hub_GP28 PF11110.8 EPE36939.1 - 0.074 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Baseplate hub distal subunit CPSase_L_D2 PF02786.17 EPE36940.1 - 1.1e-72 244.0 0.0 1.6e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EPE36940.1 - 6.3e-37 126.0 0.0 1.2e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 EPE36940.1 - 3.8e-36 124.0 0.0 7.4e-36 123.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 EPE36940.1 - 6.2e-12 45.2 0.3 2.4e-11 43.3 0.2 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EPE36940.1 - 1.3e-07 31.4 0.0 2.9e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EPE36940.1 - 3.1e-06 26.9 0.0 5.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EPE36940.1 - 0.0098 15.5 0.0 0.023 14.3 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.19 EPE36940.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 EPE36940.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EPE36940.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Biotin-lipoyl like SH3_1 PF00018.28 EPE36941.1 - 5.4e-09 35.5 0.1 8.8e-09 34.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPE36941.1 - 3.8e-07 29.9 0.0 7.8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EPE36941.1 - 3.3e-05 23.5 0.0 6.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF1129 PF06570.11 EPE36941.1 - 4.5 6.7 8.1 1.1 8.7 2.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) TRAM_LAG1_CLN8 PF03798.16 EPE36942.1 - 2.9e-46 157.7 17.7 2.9e-46 157.7 17.7 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EPE36942.1 - 1.2e-20 72.9 0.0 3.2e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein ECF_trnsprt PF12822.7 EPE36942.1 - 0.78 9.8 0.0 0.78 9.8 0.0 2.8 4 0 0 4 4 4 0 ECF transporter, substrate-specific component Bax1-I PF01027.20 EPE36943.1 - 2.8e-54 184.1 26.1 3.3e-54 183.9 26.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SfLAP PF11139.8 EPE36943.1 - 0.0078 15.7 0.7 0.0078 15.7 0.7 2.4 2 1 0 2 2 2 1 Sap, sulfolipid-1-addressing protein zf-C2H2_4 PF13894.6 EPE36944.1 - 1.7e-05 25.2 5.3 0.014 16.2 0.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EPE36944.1 - 0.0001 22.5 8.2 0.1 13.1 2.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 EPE36944.1 - 0.0011 19.2 2.1 0.013 15.7 0.0 2.2 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 EPE36944.1 - 0.047 14.0 1.0 0.047 14.0 1.0 1.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 EPE36944.1 - 0.054 13.3 8.5 0.074 12.9 2.0 2.3 1 1 1 2 2 2 0 GAGA factor zf-met PF12874.7 EPE36944.1 - 0.071 13.5 0.5 0.14 12.6 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DEC-1_N PF04625.13 EPE36944.1 - 0.37 9.8 2.4 1.1 8.1 2.4 1.8 1 1 0 1 1 1 0 DEC-1 protein, N-terminal region zf-C2H2_2 PF12756.7 EPE36944.1 - 0.63 10.4 4.9 12 6.3 2.9 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 EPE36944.1 - 0.84 10.1 2.7 1.5 9.3 2.7 1.4 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Ecm33 PF12454.8 EPE36946.1 - 0.0094 16.1 0.7 0.026 14.6 0.7 1.8 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Chorion_1 PF01723.16 EPE36946.1 - 1.2 9.1 4.6 2 8.4 0.4 2.2 2 0 0 2 2 2 0 Chorion protein Carboxyl_trans PF01039.22 EPE36947.1 - 2.9e-136 455.0 0.1 3.4e-136 454.8 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Acyl-CoA_dh_1 PF00441.24 EPE36948.1 - 4.8e-41 140.5 0.7 8.5e-41 139.7 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EPE36948.1 - 5.1e-31 107.7 0.0 1.1e-30 106.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EPE36948.1 - 2.8e-27 94.7 0.2 5.8e-27 93.7 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EPE36948.1 - 4.6e-15 56.1 0.1 8.7e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EPE36948.1 - 0.00015 21.5 0.3 0.0012 18.6 0.1 2.3 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal PHD PF00628.29 EPE36949.1 - 3.6e-10 39.6 2.1 8.3e-10 38.4 2.1 1.6 1 0 0 1 1 1 1 PHD-finger UIM PF02809.20 EPE36949.1 - 0.0033 17.2 0.5 0.01 15.7 0.5 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif PHD_2 PF13831.6 EPE36949.1 - 0.067 12.8 2.8 0.11 12.1 2.8 1.4 1 0 0 1 1 1 0 PHD-finger NP1-WLL PF11733.8 EPE36950.1 - 0.13 12.0 0.1 0.13 12.0 0.1 2.3 2 0 0 2 2 2 0 Non-capsid protein NP1 GA PF01468.17 EPE36951.1 - 0.058 13.7 0.4 0.14 12.5 0.4 1.6 1 0 0 1 1 1 0 GA module Cu_amine_oxid PF01179.20 EPE36955.1 - 1e-169 564.8 0.0 1.3e-169 564.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 EPE36955.1 - 0.00011 22.3 0.6 0.00024 21.3 0.1 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain IBN_N PF03810.19 EPE36956.1 - 8.5e-13 48.0 0.1 3.3e-11 42.9 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 EPE36956.1 - 2.5e-05 23.3 0.2 0.00012 21.0 0.0 2.2 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 EPE36956.1 - 0.00056 18.5 0.9 0.0082 14.7 0.0 2.7 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus HEAT_2 PF13646.6 EPE36956.1 - 0.0047 17.3 0.9 2.8 8.4 0.1 3.5 2 1 1 3 3 3 2 HEAT repeats GRIP PF01465.20 EPE36956.1 - 0.016 15.1 0.1 0.098 12.6 0.1 2.5 1 1 0 1 1 1 0 GRIP domain RTP1_C1 PF10363.9 EPE36956.1 - 0.02 15.1 0.6 0.31 11.2 0.1 3.1 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Xpo1 PF08389.12 EPE36956.1 - 0.039 14.0 4.3 0.25 11.4 0.1 3.7 4 0 0 4 4 4 0 Exportin 1-like protein Cnd1 PF12717.7 EPE36956.1 - 0.11 12.6 0.7 1.1 9.3 0.1 2.9 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 EPE36956.1 - 0.12 12.1 0.1 9.7 5.9 0.0 3.6 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 EPE36956.1 - 0.34 11.5 1.9 1.5 9.5 0.0 3.1 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Mcp5_PH PF12814.7 EPE36957.1 - 2.5e-44 150.3 0.1 5.6e-44 149.2 0.1 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EPE36957.1 - 0.0004 20.9 0.0 0.0014 19.1 0.0 2.0 2 0 0 2 2 2 1 PH domain zf-CCCH PF00642.24 EPE36958.1 - 1.7e-08 34.1 2.5 3.4e-08 33.2 2.5 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 EPE36958.1 - 2.3e-08 33.8 4.8 4.3e-08 32.9 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPE36958.1 - 1.4e-07 31.2 6.6 2.6e-07 30.3 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPE36958.1 - 2.3e-07 30.7 5.0 4.7e-07 29.7 5.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EPE36958.1 - 3.7e-07 29.9 7.5 6.8e-07 29.1 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPE36958.1 - 1.6e-06 27.9 7.2 2.8e-06 27.2 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 EPE36958.1 - 6.1e-06 26.3 2.4 6.1e-06 26.3 2.4 2.1 3 0 0 3 3 2 1 zinc RING finger of MSL2 zf_CCCH_4 PF18345.1 EPE36958.1 - 1.9e-05 24.5 6.2 3.6e-05 23.7 6.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_2 PF13639.6 EPE36958.1 - 2e-05 24.8 5.8 3.7e-05 24.0 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 EPE36958.1 - 0.0002 21.1 2.6 0.0002 21.1 2.6 2.0 2 0 0 2 2 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 EPE36958.1 - 0.00025 20.8 5.3 0.00049 19.9 5.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EPE36958.1 - 0.0013 18.8 6.6 0.0032 17.6 6.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 EPE36958.1 - 0.092 13.3 3.6 0.18 12.4 3.6 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Cript PF10235.9 EPE36958.1 - 1.1 9.9 9.4 0.11 13.0 3.9 2.2 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT Abhydrolase_1 PF00561.20 EPE36959.1 - 1.4e-23 83.9 0.0 3e-23 82.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EPE36959.1 - 3.2e-21 74.7 0.1 8.3e-21 73.3 0.1 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EPE36959.1 - 0.00079 18.8 0.0 0.093 12.0 0.0 2.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 EPE36959.1 - 0.0054 16.4 0.1 4 7.0 0.0 2.5 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EPE36959.1 - 0.034 13.9 0.1 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pet191_N PF10203.9 EPE36960.1 - 2e-27 95.3 3.8 3e-27 94.7 3.8 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.12 EPE36960.1 - 0.011 15.5 0.3 0.035 13.9 0.2 1.8 2 0 0 2 2 2 0 PAN-like domain Cmc1 PF08583.10 EPE36960.1 - 0.37 10.8 2.9 1.2 9.2 0.5 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 EPE36960.1 - 8.8 6.4 7.6 3.6 7.7 0.4 2.8 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF1993 PF09351.10 EPE36961.1 - 1e-50 172.0 0.0 1.2e-50 171.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) 2OG-FeII_Oxy_3 PF13640.6 EPE36962.1 - 3e-10 40.9 0.0 5.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SWIRM PF04433.17 EPE36966.1 - 7.3e-13 48.7 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Thioredox_DsbH PF03190.15 EPE36967.1 - 6.3e-71 237.6 0.0 1.1e-70 236.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 EPE36967.1 - 2.8e-08 33.8 0.0 5.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_76 PF03663.14 EPE36967.1 - 0.00021 20.9 0.1 0.0004 20.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 A_deaminase PF00962.22 EPE36971.1 - 1.8e-41 142.5 0.0 3e-41 141.8 0.0 1.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase RRM_1 PF00076.22 EPE36972.1 - 5.4e-18 64.6 0.0 1e-12 47.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EPE36972.1 - 0.0036 17.1 0.0 0.49 10.2 0.0 2.3 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 EPE36972.1 - 0.047 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif MFS_1 PF07690.16 EPE36973.1 - 3.3e-42 144.7 38.0 1.4e-39 136.0 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE36973.1 - 6.5e-10 38.4 3.6 1.1e-09 37.7 3.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EPE36973.1 - 0.00024 20.5 4.0 0.00024 20.5 4.0 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4190 PF13828.6 EPE36973.1 - 0.019 14.7 1.2 0.86 9.4 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) p450 PF00067.22 EPE36974.1 - 7.8e-61 206.2 0.0 1e-60 205.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 EPE36975.1 - 2.4e-05 24.1 2.0 6.1e-05 22.8 2.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPE36975.1 - 6.3e-05 22.7 1.3 0.00014 21.7 1.3 1.6 1 0 0 1 1 1 1 F-box domain Pex16 PF08610.10 EPE36976.1 - 7.6e-133 442.7 1.2 8.6e-133 442.5 1.2 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Nucleos_tra2_N PF01773.20 EPE36976.1 - 0.22 12.1 0.4 13 6.4 0.1 2.3 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus Alpha-L-AF_C PF06964.12 EPE36977.1 - 2.9e-23 82.8 0.9 4.5e-23 82.2 0.4 1.5 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain NTS PF15447.6 EPE36978.1 - 0.0052 17.2 0.4 0.015 15.8 0.4 1.8 1 0 0 1 1 1 1 N-terminal segments of PfEMP1 Fungal_trans_2 PF11951.8 EPE36979.1 - 2.2e-09 36.7 2.0 2.9e-09 36.2 0.9 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE36979.1 - 7.2e-09 35.6 8.6 1.4e-08 34.7 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DJ-1_PfpI PF01965.24 EPE36980.1 - 7e-10 39.0 0.0 1.4e-09 38.0 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EPE36980.1 - 4.6e-05 23.2 0.0 0.0001 22.1 0.0 1.8 1 1 0 1 1 1 1 ThiJ/PfpI family-like Glyco_hydro_10 PF00331.20 EPE36981.1 - 2.4e-99 332.5 0.3 2.7e-99 332.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF2680 PF10925.8 EPE36981.1 - 0.093 12.7 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) APH PF01636.23 EPE36982.1 - 9.3e-07 29.0 0.0 2.3e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Skp1 PF01466.19 EPE36983.1 - 0.17 12.0 0.9 0.42 10.8 0.9 1.8 1 1 1 2 2 2 0 Skp1 family, dimerisation domain adh_short PF00106.25 EPE36985.1 - 2.2e-42 144.7 0.0 2.9e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE36985.1 - 4.5e-31 108.2 0.0 5.5e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE36985.1 - 4.4e-09 36.5 0.0 6.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE36985.1 - 1.6e-05 24.2 0.0 2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EPE36985.1 - 2.6e-05 24.2 0.1 5.4e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 EPE36985.1 - 0.00026 21.1 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EPE36985.1 - 0.0018 17.8 0.0 0.0062 16.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 EPE36985.1 - 0.03 14.5 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1451 PF07295.11 EPE36985.1 - 0.095 12.7 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Ras PF00071.22 EPE36987.1 - 3.6e-45 153.5 0.0 4.4e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPE36987.1 - 2e-15 57.0 0.0 3.3e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPE36987.1 - 1.1e-08 34.7 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EPE36987.1 - 0.00012 21.7 0.0 0.005 16.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EPE36987.1 - 0.00041 20.3 0.1 0.86 9.5 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EPE36987.1 - 0.005 16.9 0.0 0.0085 16.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EPE36987.1 - 0.027 14.8 0.0 0.34 11.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.20 EPE36987.1 - 0.071 12.3 0.0 10 5.1 0.0 2.1 1 1 0 2 2 2 0 G-protein alpha subunit Septin PF00735.18 EPE36987.1 - 0.093 12.0 0.0 0.32 10.2 0.0 1.8 1 1 0 2 2 2 0 Septin SRPRB PF09439.10 EPE36987.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MFS_2 PF13347.6 EPE36990.1 - 2.2e-05 23.2 2.8 2.2e-05 23.2 2.8 2.9 3 2 0 3 3 3 2 MFS/sugar transport protein Fungal_trans_2 PF11951.8 EPE36991.1 - 6.8e-12 44.9 0.4 1.1e-11 44.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE36991.1 - 2.5e-07 30.7 8.4 4.6e-07 29.9 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trp_repressor PF01371.19 EPE36991.1 - 0.016 15.3 0.0 0.098 12.8 0.0 2.3 2 0 0 2 2 2 0 Trp repressor protein Nop14 PF04147.12 EPE36992.1 - 0.47 8.6 18.8 0.51 8.5 18.8 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EPE36992.1 - 5.1 6.4 20.2 5.6 6.3 20.2 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 EPE36992.1 - 8.3 5.1 9.0 9.1 4.9 9.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF968 PF06147.11 EPE36993.1 - 0.073 13.3 0.9 0.17 12.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF968) Glyco_hydro_2_C PF02836.17 EPE36995.1 - 3.1e-107 358.2 0.1 7.8e-107 356.9 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 EPE36995.1 - 8.8e-66 222.0 0.0 4.6e-65 219.6 0.0 2.1 2 0 0 2 2 2 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 EPE36995.1 - 3.3e-46 157.3 1.2 1.7e-45 155.0 0.6 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 EPE36995.1 - 1.2e-22 80.1 0.1 4.5e-22 78.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 EPE36995.1 - 6.1e-14 52.6 0.2 2.6e-13 50.6 0.2 2.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_17 PF00332.18 EPE36998.1 - 1.6e-40 139.7 0.9 4.9e-40 138.1 0.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 F_bP_aldolase PF01116.20 EPE36998.1 - 0.069 12.6 0.1 0.1 12.1 0.1 1.1 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II PQ-loop PF04193.14 EPE36999.1 - 2.2e-38 129.8 8.8 2.6e-19 68.7 0.0 2.9 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 EPE36999.1 - 0.017 16.0 4.9 0.11 13.3 0.2 3.0 2 1 1 3 3 3 0 ER lumen protein retaining receptor NAD_binding_10 PF13460.6 EPE37000.1 - 1.5e-11 44.5 0.0 1.8e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPE37000.1 - 3.6e-05 23.4 0.0 4.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EPE37000.1 - 0.004 16.7 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family p450 PF00067.22 EPE37001.1 - 8.7e-60 202.8 0.0 3.8e-58 197.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 HET PF06985.11 EPE37003.1 - 7.2e-29 101.0 0.0 1.3e-28 100.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 EPE37004.1 - 8.1e-18 64.5 42.8 4.3e-16 58.8 36.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPE37004.1 - 8.2e-05 21.6 30.7 0.027 13.3 30.7 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3483 PF11982.8 EPE37004.1 - 0.032 13.8 1.4 0.077 12.6 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) DUF1980 PF09323.10 EPE37004.1 - 0.19 11.6 0.0 0.54 10.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Peptidase_M43 PF05572.13 EPE37005.1 - 1.6e-13 50.8 0.8 2.9e-13 50.0 0.8 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EPE37005.1 - 2.6e-07 31.0 1.3 4e-07 30.4 1.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EPE37005.1 - 1.5e-05 24.8 4.0 3.1e-05 23.7 3.9 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EPE37005.1 - 4.4e-05 24.0 0.4 7.3e-05 23.3 0.4 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EPE37005.1 - 0.00011 22.1 0.3 0.00024 21.1 0.2 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EPE37005.1 - 0.00049 19.1 0.3 0.0007 18.6 0.3 1.2 1 0 0 1 1 1 1 Peptidase M66 DUF4953 PF16313.5 EPE37005.1 - 0.0011 18.3 0.1 0.0017 17.6 0.1 1.3 1 0 0 1 1 1 1 Met-zincin Peptidase_M10 PF00413.24 EPE37005.1 - 0.0046 16.8 0.0 0.0061 16.4 0.0 1.3 1 0 0 1 1 1 1 Matrixin Metallopep PF12044.8 EPE37005.1 - 0.016 13.8 1.3 0.025 13.2 1.3 1.2 1 0 0 1 1 1 0 Putative peptidase family Ring_hydroxyl_A PF00848.19 EPE37006.1 - 7.7e-22 78.3 0.0 3.9e-10 40.1 0.0 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 EPE37007.1 - 2.4e-15 56.2 0.0 4e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 EPE37007.1 - 0.021 14.8 0.3 7.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) AA_permease_2 PF13520.6 EPE37008.1 - 1.1e-49 169.4 41.1 1.5e-49 169.0 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE37008.1 - 1.6e-18 66.5 33.4 2.5e-18 65.9 33.4 1.2 1 0 0 1 1 1 1 Amino acid permease Bac_export_2 PF01312.19 EPE37008.1 - 3.3 6.8 5.4 0.6 9.3 0.1 2.2 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family Esterase_phd PF10503.9 EPE37010.1 - 1.1e-23 84.0 0.7 1.4e-23 83.5 0.7 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EPE37010.1 - 7.2e-09 35.4 0.6 1.3e-08 34.6 0.6 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Glyco_hydro_76 PF03663.14 EPE37012.1 - 1.1e-29 104.1 0.1 1.5e-29 103.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EPE37012.1 - 4.9e-09 35.7 0.0 0.00056 19.1 0.0 3.1 1 1 2 3 3 3 3 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 EPE37012.1 - 0.0058 16.2 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus GlcNAc_2-epim PF07221.11 EPE37012.1 - 0.012 14.9 0.2 1 8.5 0.1 2.5 2 1 0 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) p450 PF00067.22 EPE37014.1 - 1.9e-56 191.7 0.0 2.5e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 But2 PF09792.9 EPE37016.1 - 0.00013 22.3 0.4 0.00019 21.9 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain AAA_33 PF13671.6 EPE37017.1 - 2e-10 41.0 0.0 2.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EPE37017.1 - 8.4e-07 28.5 0.0 1.4e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 EPE37017.1 - 1.7e-05 25.4 0.0 3e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EPE37017.1 - 0.0018 18.7 0.0 0.0042 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 EPE37017.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.6 1 1 1 2 2 2 0 Dephospho-CoA kinase KAP_NTPase PF07693.14 EPE37017.1 - 0.016 14.5 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 EPE37017.1 - 0.048 14.0 0.0 0.077 13.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 EPE37017.1 - 0.051 13.5 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_29 PF13555.6 EPE37017.1 - 0.11 12.2 0.5 0.71 9.7 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EPE37017.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 EPE37017.1 - 0.12 12.9 0.1 0.26 11.8 0.1 1.4 1 1 0 1 1 1 0 ABC transporter Methyltr_RsmB-F PF01189.17 EPE37017.1 - 0.16 11.5 0.0 0.38 10.4 0.0 1.5 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F Fungal_trans PF04082.18 EPE37018.1 - 5.2e-06 25.7 0.0 8.5e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3_C PF01915.22 EPE37019.1 - 1e-58 198.7 0.0 3.4e-58 197.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPE37019.1 - 3.2e-45 154.9 0.0 5e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPE37019.1 - 2.4e-20 72.4 0.0 4.8e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EPE37019.1 - 1.4e-08 34.7 0.3 3.7e-08 33.3 0.3 1.7 1 0 0 1 1 1 1 PA14 domain Sugar_tr PF00083.24 EPE37020.1 - 2.4e-76 257.4 23.7 2.9e-76 257.2 23.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPE37020.1 - 1.6e-12 47.0 27.4 1.3e-11 44.0 25.9 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2574 PF10836.8 EPE37020.1 - 0.1 12.5 0.3 0.29 11.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) Zn_clus PF00172.18 EPE37021.1 - 2.8e-12 46.5 9.4 3.8e-12 46.1 9.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPE37022.1 - 1.8e-15 56.7 0.1 2.7e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EPE37024.1 - 2.5e-48 164.8 63.7 3.9e-47 160.9 61.6 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EPE37024.1 - 8.3e-17 60.8 15.7 1.2e-16 60.3 15.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPE37024.1 - 1.3e-14 54.0 14.6 1.3e-14 54.0 14.6 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 EPE37024.1 - 0.052 11.8 15.8 0.48 8.6 10.4 2.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family YlaC PF10777.9 EPE37024.1 - 0.065 13.1 0.7 2.4 8.0 0.1 2.6 2 0 0 2 2 2 0 Inner membrane protein YlaC p450 PF00067.22 EPE37028.1 - 4.6e-10 38.8 0.0 5.1e-10 38.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 EPE37030.1 - 1.5e-19 70.5 0.0 4e-06 26.3 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 EPE37030.1 - 5.2e-06 25.9 0.0 0.0037 16.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPE37030.1 - 2.6e-05 24.7 0.0 0.094 13.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPE37030.1 - 7.3e-05 22.9 0.1 0.00015 21.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EPE37030.1 - 0.00024 19.9 0.3 0.0013 17.5 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EPE37030.1 - 0.00044 19.6 0.0 0.0084 15.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE37030.1 - 0.0013 17.9 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EPE37030.1 - 0.0028 17.0 0.6 0.68 9.2 0.0 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase DAO PF01266.24 EPE37030.1 - 0.0033 17.1 0.1 0.0088 15.7 0.1 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EPE37030.1 - 0.0091 15.1 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EPE37030.1 - 0.034 13.4 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family M20_dimer PF07687.14 EPE37030.1 - 0.077 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Peptidase dimerisation domain AlaDh_PNT_C PF01262.21 EPE37030.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_23 PF13489.6 EPE37031.1 - 1.2e-18 67.5 0.0 2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE37031.1 - 8.2e-08 32.9 0.0 2.8e-07 31.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE37031.1 - 1.7e-06 28.6 0.0 8.2e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE37031.1 - 3.8e-06 26.8 0.0 0.012 15.4 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EPE37031.1 - 1.6e-05 25.4 0.0 3.5e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EPE37031.1 - 0.0071 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EPE37031.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 EPE37031.1 - 0.036 13.4 0.0 0.5 9.6 0.0 2.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 EPE37031.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.17 EPE37031.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase zinc_ribbon_10 PF10058.9 EPE37033.1 - 7.7e-20 70.4 0.1 1.4e-19 69.5 0.1 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein BLUF PF04940.12 EPE37033.1 - 0.015 15.4 0.3 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Sensors of blue-light using FAD DUF2207 PF09972.9 EPE37033.1 - 0.069 11.9 0.1 0.094 11.5 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AHSP PF09236.10 EPE37033.1 - 0.31 11.5 1.5 0.96 9.9 0.1 2.1 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein GRIP PF01465.20 EPE37034.1 - 4.9e-06 26.4 0.1 1.2e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 GRIP domain DHR10 PF18595.1 EPE37034.1 - 0.00068 19.7 8.3 0.00068 19.7 8.3 9.9 3 2 6 10 10 10 5 Designed helical repeat protein 10 domain WD40_alt PF14077.6 EPE37034.1 - 0.0075 16.1 11.7 1 9.3 0.1 5.5 4 0 0 4 4 4 2 Alternative WD40 repeat motif DUF4201 PF13870.6 EPE37034.1 - 0.01 15.6 4.1 0.01 15.6 4.1 9.1 3 2 6 9 9 9 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.12 EPE37034.1 - 0.93 9.6 139.0 0.9 9.6 14.3 11.1 4 2 7 11 11 11 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EPE37034.1 - 3.6 6.4 132.8 0.012 14.5 13.6 8.5 2 2 7 9 9 9 0 Spc7 kinetochore protein Pkinase PF00069.25 EPE37035.1 - 7e-40 137.1 0.0 1.4e-22 80.3 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPE37035.1 - 1.2e-14 54.2 0.2 2.6e-10 40.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPE37035.1 - 0.026 13.3 5.4 0.011 14.6 1.3 2.1 1 1 1 2 2 2 0 Fungal protein kinase Brr6_like_C_C PF10104.9 EPE37036.1 - 5e-42 142.8 0.2 6.3e-42 142.5 0.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain TIP_N PF12457.8 EPE37036.1 - 0.01 16.2 0.4 0.026 14.9 0.4 1.6 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal Med26 PF08711.11 EPE37037.1 - 3.8e-09 36.4 0.0 7.8e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain HLH PF00010.26 EPE37038.1 - 9.2e-17 60.8 0.6 1.8e-16 59.8 0.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 EPE37038.1 - 0.0048 17.0 0.3 0.016 15.3 0.2 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EPE37038.1 - 0.015 15.4 0.2 0.062 13.4 0.1 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Fungal_trans PF04082.18 EPE37039.1 - 9.7e-24 83.8 0.4 1.5e-23 83.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE37039.1 - 1.4e-07 31.5 9.2 2.7e-07 30.6 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu-oxidase_3 PF07732.15 EPE37040.1 - 5.5e-40 136.1 1.2 1e-36 125.5 0.1 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EPE37040.1 - 3.2e-31 107.9 3.6 7.5e-31 106.7 0.3 2.7 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EPE37040.1 - 3.5e-16 59.7 0.0 1e-15 58.2 0.0 1.8 1 0 0 1 1 1 1 Multicopper oxidase NSs PF11073.8 EPE37040.1 - 0.06 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like Phosphoesterase PF04185.14 EPE37041.1 - 1.2e-59 202.3 0.2 2.1e-59 201.5 0.2 1.2 1 0 0 1 1 1 1 Phosphoesterase family CREPT PF16566.5 EPE37041.1 - 0.24 11.6 0.0 0.48 10.6 0.0 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour RAMP PF04901.13 EPE37042.1 - 0.14 12.2 0.1 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Receptor activity modifying family PNGaseA PF12222.8 EPE37048.1 - 4.4e-181 602.5 5.0 6.5e-181 601.9 5.0 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A EamA PF00892.20 EPE37049.1 - 9.1e-18 64.8 28.2 6.6e-12 45.8 7.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family TFIID-18kDa PF02269.16 EPE37050.1 - 9.2e-20 70.5 0.1 1.3e-19 69.9 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.6 EPE37050.1 - 0.035 14.5 0.3 0.075 13.4 0.0 1.7 2 1 0 2 2 2 0 CENP-S protein CBFD_NFYB_HMF PF00808.23 EPE37050.1 - 0.048 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF5315 PF17242.2 EPE37051.1 - 7.6e-29 99.4 1.7 1.7e-28 98.3 1.7 1.6 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) Ribosom_S12_S23 PF00164.25 EPE37052.1 - 4.1e-51 171.4 0.7 5e-51 171.1 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 SUR7 PF06687.12 EPE37053.1 - 4.2e-40 137.6 21.7 5.2e-40 137.3 21.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family PIG-P PF08510.12 EPE37053.1 - 3.5 7.5 9.8 6.7 6.6 6.4 2.4 2 0 0 2 2 2 0 PIG-P sCache_3_3 PF17202.4 EPE37054.1 - 0.25 11.8 1.5 2.7 8.5 0.0 2.5 2 0 0 2 2 2 0 Single cache domain 3 DEAD PF00270.29 EPE37055.1 - 1.7e-17 63.7 0.0 3.9e-17 62.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPE37055.1 - 8.4e-16 58.3 0.0 6.5e-14 52.2 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EPE37055.1 - 2.6e-10 40.8 1.5 7e-10 39.5 1.5 1.7 1 0 0 1 1 1 1 RecQ zinc-binding PP2C PF00481.21 EPE37056.1 - 4.3e-44 151.1 0.0 7.2e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EPE37056.1 - 0.0024 17.8 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) YopE PF03545.13 EPE37056.1 - 0.079 13.1 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) PP2C_2 PF13672.6 EPE37056.1 - 0.091 12.4 0.0 0.24 11.0 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C Tcf25 PF04910.14 EPE37057.1 - 1.1e-67 228.6 0.8 1.7e-67 228.0 0.8 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 STAT2_C PF12188.8 EPE37057.1 - 0.03 14.3 0.4 0.13 12.2 0.1 2.2 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal Wbp11 PF09429.10 EPE37057.1 - 1.2 9.6 16.8 0.12 12.8 7.3 2.5 2 0 0 2 2 2 0 WW domain binding protein 11 HMA PF00403.26 EPE37058.1 - 1.1e-10 41.8 3.0 5.8e-05 23.4 0.4 2.2 2 0 0 2 2 2 2 Heavy-metal-associated domain BRK PF07533.16 EPE37058.1 - 0.11 12.1 0.4 18 5.1 0.0 2.3 2 0 0 2 2 2 0 BRK domain Thiolase_N PF00108.23 EPE37059.1 - 3.4e-16 59.4 0.0 1.1e-15 57.7 0.0 1.9 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EPE37059.1 - 5.5e-12 45.4 1.4 1.6e-11 43.9 0.0 2.4 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EPE37059.1 - 7.6e-06 25.7 0.0 0.00044 20.0 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EPE37059.1 - 1.4e-05 24.8 0.1 4.3e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EPE37059.1 - 0.058 13.4 0.0 11 6.1 0.0 2.7 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DUF3824 PF12868.7 EPE37060.1 - 0.0085 16.8 2.7 0.0085 16.8 2.7 8.2 7 1 0 7 7 7 4 Domain of unknwon function (DUF3824) EcsC PF12787.7 EPE37060.1 - 0.39 10.4 1.2 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 EcsC protein family Glyco_hydro_61 PF03443.14 EPE37061.1 - 3.6e-58 196.9 0.1 4.3e-58 196.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Tcp11 PF05794.13 EPE37062.1 - 6.3e-101 338.6 6.4 8.2e-100 335.0 6.4 2.0 1 1 0 1 1 1 1 T-complex protein 11 TGT PF01702.18 EPE37065.1 - 5.2e-142 473.1 0.0 6.1e-142 472.9 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase RecA_dep_nuc PF16786.5 EPE37065.1 - 0.052 13.7 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 Recombination enhancement, RecA-dependent nuclease IL12 PF03039.14 EPE37066.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Interleukin-12 alpha subunit adh_short PF00106.25 EPE37067.1 - 5.8e-18 65.0 0.1 3.1e-17 62.7 0.1 1.8 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPE37067.1 - 1.3e-11 44.5 0.0 1.8e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPE37067.1 - 4.1e-07 30.1 0.0 6.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPE37067.1 - 0.045 13.2 0.1 0.059 12.8 0.1 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPE37067.1 - 0.05 13.2 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family HET PF06985.11 EPE37069.1 - 2.3e-32 112.4 0.1 4.3e-32 111.5 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MOZ_SAS PF01853.18 EPE37070.1 - 1.4e-80 269.2 0.5 2e-80 268.6 0.5 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EPE37070.1 - 5.4e-22 77.2 2.4 1.1e-21 76.2 2.4 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EPE37070.1 - 4.7e-18 64.8 0.0 1.7e-17 63.0 0.0 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EPE37070.1 - 0.00024 21.4 0.0 0.00048 20.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE37070.1 - 0.017 15.4 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Pox_Ag35 PF03286.14 EPE37070.1 - 0.034 13.9 5.9 0.073 12.9 5.9 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNase_T PF00929.24 EPE37071.1 - 1e-16 61.9 0.0 3.3e-16 60.3 0.0 1.8 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EPE37071.1 - 0.00026 20.8 0.0 0.00093 18.9 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease CMAS PF02353.20 EPE37072.1 - 2.7e-71 240.0 0.0 5.2e-71 239.1 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EPE37072.1 - 4e-13 49.8 0.0 8.5e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPE37072.1 - 5e-13 49.6 0.0 1e-12 48.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPE37072.1 - 2e-08 34.2 0.0 3.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPE37072.1 - 1.7e-05 24.6 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPE37072.1 - 3e-05 24.7 0.0 6.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EPE37072.1 - 0.055 13.2 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_3 PF01596.17 EPE37072.1 - 0.062 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF938 PF06080.12 EPE37072.1 - 0.069 12.9 0.0 0.56 9.9 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 EPE37072.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RNase_H2_suC PF08615.11 EPE37074.1 - 2.5e-33 115.2 0.0 3e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF4385 PF14328.6 EPE37075.1 - 8.5e-56 188.1 2.6 8.5e-56 188.1 2.6 1.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4385) MCM PF00493.23 EPE37076.1 - 3.6e-103 343.5 0.1 6e-103 342.8 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EPE37076.1 - 4e-38 130.1 0.2 7.9e-38 129.1 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EPE37076.1 - 2.1e-31 108.4 0.2 3.8e-31 107.5 0.2 1.5 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 EPE37076.1 - 2.8e-24 85.7 0.2 7.2e-24 84.4 0.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 EPE37076.1 - 1.4e-23 83.1 0.2 4.6e-23 81.5 0.2 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EPE37076.1 - 2.6e-08 33.5 0.0 7.8e-07 28.7 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EPE37076.1 - 0.00098 19.0 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EPE37076.1 - 0.0013 18.5 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EPE37076.1 - 0.0049 16.9 0.0 0.02 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RPAP1_N PF08621.10 EPE37076.1 - 0.17 11.7 0.4 0.61 9.9 0.4 1.9 1 0 0 1 1 1 0 RPAP1-like, N-terminal Hist_deacetyl PF00850.19 EPE37077.1 - 1.9e-51 175.4 0.0 3e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Lon_C PF05362.13 EPE37080.1 - 1.1e-68 230.8 0.2 2.2e-68 229.9 0.2 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EPE37080.1 - 3.1e-28 99.1 0.0 6.1e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EPE37080.1 - 2.7e-23 82.8 0.0 7.3e-23 81.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EPE37080.1 - 6.7e-08 32.6 0.0 2.1e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EPE37080.1 - 2.5e-07 30.6 0.0 7.4e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EPE37080.1 - 2.3e-05 24.9 0.0 6.8e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_3 PF07726.11 EPE37080.1 - 2.5e-05 24.1 0.0 7.4e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EPE37080.1 - 3.5e-05 23.6 0.0 8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 EPE37080.1 - 0.00011 22.4 0.0 0.00042 20.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EPE37080.1 - 0.00016 21.4 0.0 0.00065 19.5 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EPE37080.1 - 0.0017 17.6 0.1 0.0035 16.6 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EPE37080.1 - 0.0028 17.9 0.0 0.04 14.2 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EPE37080.1 - 0.0043 17.1 0.0 0.075 13.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 EPE37080.1 - 0.008 16.1 0.1 0.019 14.9 0.1 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 EPE37080.1 - 0.016 15.8 0.0 0.049 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EPE37080.1 - 0.016 15.3 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EPE37080.1 - 0.027 14.9 0.3 0.096 13.1 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_25 PF13481.6 EPE37080.1 - 0.032 13.8 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RSS_P20 PF11757.8 EPE37080.1 - 0.035 14.6 0.1 0.095 13.1 0.1 1.7 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain NTPase_1 PF03266.15 EPE37080.1 - 0.037 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 EPE37080.1 - 0.04 13.8 0.1 0.14 12.1 0.0 1.9 2 0 0 2 2 1 0 NACHT domain RsgA_GTPase PF03193.16 EPE37080.1 - 0.045 13.7 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 EPE37080.1 - 0.06 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EPE37080.1 - 0.083 12.3 0.1 0.23 10.8 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.11 EPE37080.1 - 0.098 11.6 0.1 4.7 6.0 0.1 2.3 2 0 0 2 2 2 0 PrkA AAA domain CENP-X PF09415.10 EPE37080.1 - 0.12 12.8 0.2 0.66 10.3 0.2 2.3 1 1 0 1 1 1 0 CENP-S associating Centromere protein X AAA_23 PF13476.6 EPE37080.1 - 0.66 10.4 0.0 0.66 10.4 0.0 3.3 2 1 1 3 3 1 0 AAA domain PLDc_2 PF13091.6 EPE37081.1 - 4.4e-19 68.7 0.0 4.7e-13 49.2 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EPE37081.1 - 0.00089 19.3 0.1 0.011 15.8 0.1 2.3 2 0 0 2 2 2 1 Phospholipase D Active site motif Regulator_TrmB PF11495.8 EPE37081.1 - 0.042 13.0 0.1 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB Ku_PK_bind PF08785.11 EPE37082.1 - 3.2e-31 108.0 0.0 7.7e-31 106.7 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 EPE37082.1 - 1.3e-30 106.6 0.0 2.5e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EPE37082.1 - 1.4e-05 25.0 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain DUF4149 PF13664.6 EPE37083.1 - 2.6e-26 91.9 1.5 2.6e-26 91.9 1.5 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Neugrin PF06413.11 EPE37084.1 - 0.01 15.8 0.8 0.01 15.8 0.8 2.2 2 1 0 2 2 2 0 Neugrin DASH_Dad4 PF08650.10 EPE37084.1 - 0.067 13.2 0.6 6.7 6.8 0.0 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad4 Ax_dynein_light PF10211.9 EPE37084.1 - 0.92 9.4 18.5 0.47 10.4 10.0 2.7 2 1 0 2 2 2 0 Axonemal dynein light chain DUF2514 PF10721.9 EPE37084.1 - 1.4 9.0 0.0 1.4 9.0 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2514) DUF4482 PF14818.6 EPE37084.1 - 1.9 9.3 15.0 1.9 9.3 0.1 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4482) GAS PF13851.6 EPE37084.1 - 5 6.4 22.5 4.9 6.5 0.5 2.7 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF5595 PF18077.1 EPE37084.1 - 5.7 7.1 7.7 1.5 9.0 2.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) DUF3432 PF11914.8 EPE37084.1 - 9.9 6.5 18.7 41 4.5 18.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3432) MA3 PF02847.17 EPE37085.1 - 1.9e-30 105.1 0.1 5.9e-30 103.6 0.0 1.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 EPE37085.1 - 2.4e-12 47.0 0.9 4.9e-12 45.9 0.9 1.5 1 0 0 1 1 1 1 MIF4G domain DPM2 PF07297.12 EPE37086.1 - 1.5e-32 111.7 1.4 1.8e-32 111.5 1.4 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EPE37086.1 - 0.00028 20.8 1.5 0.00034 20.5 1.5 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 EPE37086.1 - 0.00033 20.7 0.7 0.00033 20.7 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) Phage_holin_3_6 PF07332.11 EPE37086.1 - 0.0049 16.9 0.4 0.0057 16.7 0.4 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III LapA_dom PF06305.11 EPE37086.1 - 0.028 14.2 0.2 0.028 14.2 0.2 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain COX14 PF14880.6 EPE37086.1 - 1 9.2 3.2 2 8.3 0.0 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly ApoLp-III PF07464.11 EPE37088.1 - 0.00012 22.2 1.5 0.00027 21.1 1.5 1.5 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.7 EPE37088.1 - 0.039 14.5 0.3 0.1 13.1 0.3 1.8 1 0 0 1 1 1 0 YtxH-like protein Syntaxin_2 PF14523.6 EPE37088.1 - 0.039 14.3 0.6 0.088 13.2 0.6 1.7 1 1 0 1 1 1 0 Syntaxin-like protein AAA_13 PF13166.6 EPE37088.1 - 0.046 12.4 1.0 0.06 12.0 1.0 1.1 1 0 0 1 1 1 0 AAA domain PHA_synth_III_E PF09712.10 EPE37088.1 - 0.049 12.7 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) DUF885 PF05960.11 EPE37088.1 - 0.061 13.0 0.1 0.073 12.7 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Prefoldin_2 PF01920.20 EPE37088.1 - 0.085 12.8 0.2 0.15 12.0 0.2 1.5 1 0 0 1 1 1 0 Prefoldin subunit EFTUD2 PF16004.5 EPE37088.1 - 0.09 13.4 1.5 0.17 12.5 1.5 1.5 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus CdvA PF18822.1 EPE37088.1 - 0.095 12.5 0.5 0.19 11.6 0.5 1.5 1 0 0 1 1 1 0 CdvA-like coiled-coil domain ParB PF08775.10 EPE37088.1 - 0.14 12.7 1.8 0.14 12.6 0.7 1.7 2 0 0 2 2 1 0 ParB family DUF4358 PF14270.6 EPE37088.1 - 0.14 12.5 0.3 0.32 11.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4358) Orbi_VP1 PF05788.12 EPE37088.1 - 0.18 9.4 0.0 0.22 9.1 0.0 1.0 1 0 0 1 1 1 0 Orbivirus RNA-dependent RNA polymerase (VP1) ART PF01129.18 EPE37088.1 - 0.2 10.9 0.1 0.27 10.5 0.1 1.2 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase DUF2408 PF10303.9 EPE37088.1 - 0.21 12.1 1.3 0.42 11.2 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Seryl_tRNA_N PF02403.22 EPE37088.1 - 0.22 11.8 4.6 0.15 12.3 1.6 2.2 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain SET PF00856.28 EPE37089.1 - 1.1e-08 35.6 0.0 1.4e-06 28.8 0.0 2.6 1 1 1 2 2 2 2 SET domain zf-C6H2 PF15801.5 EPE37089.1 - 5.5 7.4 8.1 0.24 11.8 1.3 2.2 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Hydrolase_6 PF13344.6 EPE37090.1 - 3.1e-29 101.0 0.0 5.1e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPE37090.1 - 1.8e-15 56.7 0.0 1.7e-14 53.6 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EPE37090.1 - 5.8e-08 33.3 0.0 0.0037 17.6 0.0 3.0 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EPE37090.1 - 4e-05 23.8 0.1 0.12 12.4 0.0 2.6 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 EPE37090.1 - 0.07 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Glucosamine_iso PF01182.20 EPE37091.1 - 2.4e-66 223.8 0.0 2.8e-66 223.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase MukF_C PF17193.4 EPE37091.1 - 0.18 12.0 0.2 0.29 11.3 0.2 1.2 1 0 0 1 1 1 0 MukF C-terminal domain CFEM PF05730.11 EPE37092.1 - 0.00034 20.6 1.6 0.00034 20.6 1.6 2.5 2 0 0 2 2 2 1 CFEM domain Snf7 PF03357.21 EPE37093.1 - 9.8e-08 31.8 9.7 1.2e-07 31.5 9.7 1.0 1 0 0 1 1 1 1 Snf7 Pkinase_fungal PF17667.1 EPE37093.1 - 0.022 13.6 0.8 0.025 13.4 0.8 1.1 1 0 0 1 1 1 0 Fungal protein kinase Ist1 PF03398.14 EPE37093.1 - 0.03 14.2 1.9 0.037 14.0 1.9 1.1 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway bVLRF1 PF18826.1 EPE37094.1 - 2.7e-62 209.1 0.1 4.5e-62 208.3 0.1 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 EPE37094.1 - 1.4e-05 25.2 0.0 4.2e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EPE37094.1 - 0.0028 18.1 0.4 0.0064 16.9 0.4 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EPE37094.1 - 0.064 13.9 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Acyl-CoA_dh_1 PF00441.24 EPE37095.1 - 7.4e-40 136.6 4.8 1.3e-39 135.9 4.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EPE37095.1 - 2e-29 102.5 0.6 6.2e-29 100.9 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EPE37095.1 - 3.4e-23 81.7 0.0 7.6e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EPE37095.1 - 1.2e-16 61.2 1.4 2e-16 60.5 1.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.16 EPE37096.1 - 1.9e-24 86.3 45.2 6.8e-18 64.7 31.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily eIF-1a PF01176.19 EPE37097.1 - 1e-21 76.5 0.0 1.4e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.13 EPE37098.1 - 4.8e-149 496.7 19.2 5.6e-149 496.4 19.2 1.0 1 0 0 1 1 1 1 ALG3 protein Phage_DsbA PF11126.8 EPE37099.1 - 0.057 13.6 0.2 0.085 13.1 0.2 1.3 1 0 0 1 1 1 0 Transcriptional regulator DsbA HAD PF12710.7 EPE37100.1 - 6.1e-26 92.0 0.0 7.7e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EPE37100.1 - 0.00021 20.8 0.1 0.013 14.9 0.1 2.3 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 EPE37100.1 - 0.00045 19.8 0.0 0.0016 18.0 0.0 1.8 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) She9_MDM33 PF05546.11 EPE37101.1 - 2e-83 279.1 3.5 3.2e-83 278.4 3.5 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family ZapB PF06005.12 EPE37101.1 - 0.041 14.3 3.0 0.08 13.4 0.3 2.6 2 0 0 2 2 2 0 Cell division protein ZapB PsbH PF00737.20 EPE37101.1 - 0.11 12.2 1.2 0.24 11.2 1.2 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Glyco_hydro_35 PF01301.19 EPE37102.1 - 8.7e-90 301.5 0.0 1.4e-89 300.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 EPE37102.1 - 3.7e-63 212.6 6.8 5.9e-63 212.0 6.8 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 EPE37102.1 - 8.3e-57 190.7 9.3 7.2e-31 107.1 0.4 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 EPE37102.1 - 3.5e-19 68.2 0.4 1.1e-18 66.5 0.1 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Ribosom_S12_S23 PF00164.25 EPE37103.1 - 8.9e-28 96.2 0.6 1.1e-27 95.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 FAD_binding_3 PF01494.19 EPE37104.1 - 2.2e-20 73.2 0.7 3.3e-19 69.3 0.7 2.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPE37104.1 - 2e-10 40.4 0.4 0.00013 21.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPE37104.1 - 7.3e-09 35.2 0.0 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EPE37104.1 - 2.4e-08 33.1 0.9 0.00017 20.4 0.1 2.4 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.24 EPE37104.1 - 6.6e-08 32.5 0.0 0.00093 18.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 EPE37104.1 - 9.4e-08 31.5 0.2 0.00033 19.9 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EPE37104.1 - 4.6e-06 26.2 0.0 6.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPE37104.1 - 4.8e-06 26.7 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPE37104.1 - 7.1e-06 25.3 0.3 0.014 14.5 0.0 2.8 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EPE37104.1 - 7.2e-05 22.2 0.0 0.0028 16.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPE37104.1 - 0.00043 19.6 0.0 0.00079 18.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EPE37104.1 - 0.00066 20.2 0.4 0.063 13.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EPE37104.1 - 0.003 16.9 0.1 0.22 10.7 0.0 2.3 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EPE37104.1 - 0.0043 16.4 0.0 0.0091 15.3 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EPE37104.1 - 0.0074 15.2 0.1 1.9 7.3 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 EPE37104.1 - 0.036 14.1 0.4 8.1 6.4 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding p450 PF00067.22 EPE37105.1 - 6.3e-51 173.6 0.0 8e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3655 PF12379.8 EPE37105.1 - 0.15 12.4 0.0 0.38 11.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3655) Sybindin PF04099.12 EPE37105.1 - 0.15 12.0 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 Sybindin-like family FixQ PF05545.11 EPE37105.1 - 0.77 9.8 2.6 0.85 9.6 0.1 2.4 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF1772 PF08592.11 EPE37106.1 - 7.1e-22 78.2 0.5 7.1e-22 78.2 0.5 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) NmrA PF05368.13 EPE37108.1 - 2e-29 102.8 0.1 2.7e-29 102.4 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPE37108.1 - 2.6e-16 60.0 0.1 3.2e-16 59.7 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPE37108.1 - 9.2e-07 28.6 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EPE37108.1 - 0.00016 20.9 0.2 0.37 9.9 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein DapB_N PF01113.20 EPE37108.1 - 0.0016 18.5 0.2 0.0034 17.5 0.1 1.6 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 EPE37108.1 - 0.0028 16.7 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EPE37108.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 EPE37108.1 - 0.049 14.1 0.2 0.12 12.8 0.2 1.8 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Aminotran_5 PF00266.19 EPE37109.1 - 6.3e-18 64.9 0.0 6e-17 61.7 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V GST_N_4 PF17172.4 EPE37110.1 - 1.5e-22 80.2 0.0 2.4e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EPE37110.1 - 5.9e-05 22.8 0.0 0.00039 20.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EPE37110.1 - 0.0007 19.9 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.6 EPE37110.1 - 0.046 13.9 0.0 0.08 13.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EPE37110.1 - 0.057 13.8 0.1 0.24 11.9 0.1 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPE37110.1 - 0.099 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain p450 PF00067.22 EPE37112.1 - 1.3e-25 90.1 0.1 2.1e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2_4 PF13894.6 EPE37114.1 - 0.11 13.3 5.0 12 7.0 2.7 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Abhydrolase_2 PF02230.16 EPE37116.1 - 6.4e-18 65.4 0.0 1.1e-14 54.8 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EPE37116.1 - 0.1 13.2 0.8 0.19 12.3 0.8 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.18 EPE37117.1 - 1.3e-08 34.8 12.2 2.5e-08 33.9 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPE37117.1 - 0.0014 17.6 0.0 0.0026 16.6 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ldl_recept_a PF00057.18 EPE37117.1 - 7.8 6.8 12.9 0.11 12.7 5.3 1.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A XRCC4 PF06632.12 EPE37118.1 - 4.2e-08 32.4 4.5 5.9e-08 31.9 4.5 1.2 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 HTH_WhiA PF02650.14 EPE37118.1 - 0.91 9.9 4.2 2 8.8 3.7 1.9 1 1 0 1 1 1 0 WhiA C-terminal HTH domain EthD PF07110.11 EPE37120.1 - 7e-12 46.3 0.0 8.6e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 EthD domain CHAT PF12770.7 EPE37121.1 - 2.2e-41 142.2 0.1 3.4e-41 141.6 0.1 1.3 1 0 0 1 1 1 1 CHAT domain AMP-binding_C_2 PF14535.6 EPE37121.1 - 0.18 12.1 0.0 0.55 10.6 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain RE_MjaI PF09568.10 EPE37122.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 MjaI restriction endonuclease Mid2 PF04478.12 EPE37123.1 - 0.0016 18.3 8.0 0.0016 18.3 8.0 2.6 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor EssA PF10661.9 EPE37123.1 - 0.09 12.6 0.2 0.09 12.6 0.2 2.1 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA Peptidase_M56 PF05569.11 EPE37123.1 - 1 8.5 3.3 0.6 9.2 0.1 1.8 1 1 1 2 2 2 0 BlaR1 peptidase M56 Nucleo_P87 PF07267.11 EPE37123.1 - 8 5.2 17.0 10 4.8 17.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Cellulase PF00150.18 EPE37124.1 - 6.3e-43 147.2 2.8 8.6e-43 146.8 2.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 EPE37124.1 - 7.4e-16 58.0 0.1 1.9e-15 56.7 0.1 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain X2 DUF4390 PF14334.6 EPE37124.1 - 0.0026 17.2 0.1 0.0058 16.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4390) Peptidase_C39 PF03412.15 EPE37124.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase C39 family tRNA-synt_1f PF01921.18 EPE37126.1 - 0.0038 16.2 0.0 0.04 12.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (K) PFU PF09070.11 EPE37129.1 - 0.068 13.4 0.0 0.099 12.9 0.0 1.3 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) Amidoligase_2 PF12224.8 EPE37132.1 - 2.7e-11 43.6 0.0 1.7e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 Putative amidoligase enzyme EcsB PF05975.12 EPE37132.1 - 0.25 10.1 0.0 0.34 9.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB RdRP PF05183.12 EPE37134.1 - 1.5e-117 393.7 0.1 2e-117 393.3 0.1 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Hydrolase_4 PF12146.8 EPE37135.1 - 1.1e-06 28.1 0.0 2.3e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPE37135.1 - 2.3e-06 28.4 0.0 3.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 EPE37135.1 - 0.015 14.7 0.1 0.022 14.1 0.1 1.2 1 0 0 1 1 1 0 Secretory lipase DLH PF01738.18 EPE37135.1 - 0.024 14.2 0.1 6.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EPE37135.1 - 0.061 13.1 0.9 0.16 11.8 0.9 1.6 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EPE37135.1 - 0.15 11.5 0.1 5.2 6.5 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family AA_permease_2 PF13520.6 EPE37136.1 - 1.5e-46 159.1 53.2 1.9e-46 158.8 53.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPE37136.1 - 1.8e-19 69.7 35.9 1.8e-19 69.7 35.9 1.5 2 0 0 2 2 2 1 Amino acid permease Acetyltransf_7 PF13508.7 EPE37137.1 - 1.1e-09 38.5 0.0 2.2e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPE37137.1 - 9.8e-08 32.0 0.0 1.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPE37137.1 - 8.5e-07 29.2 0.1 2.7e-06 27.6 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EPE37137.1 - 0.0041 17.2 0.0 0.0071 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPE37137.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 EPE37137.1 - 0.15 12.1 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein CCDC106 PF15794.5 EPE37139.1 - 0.22 11.2 2.2 0.26 11.0 2.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Pox_Ag35 PF03286.14 EPE37139.1 - 0.68 9.7 3.0 0.84 9.4 3.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DAO PF01266.24 EPE37140.1 - 5.3e-45 154.5 0.1 6.2e-45 154.3 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EPE37140.1 - 0.00014 20.8 0.2 0.013 14.2 0.0 2.1 1 1 1 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 EPE37140.1 - 0.011 16.0 0.1 0.023 14.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EPE37140.1 - 0.034 14.1 0.4 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EPE37140.1 - 0.057 12.7 0.0 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPE37140.1 - 0.082 12.2 0.0 0.21 10.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Helo_like_N PF17111.5 EPE37142.1 - 1.7e-06 27.6 5.5 4.9e-06 26.0 5.5 1.8 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank PF00023.30 EPE37142.1 - 1.3e-05 25.4 0.1 0.012 16.1 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EPE37142.1 - 0.00053 20.2 0.0 0.0058 16.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE37142.1 - 0.0058 17.2 0.1 0.039 14.5 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Spore_YhcN_YlaJ PF09580.10 EPE37142.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF948 PF06103.11 EPE37142.1 - 0.59 10.4 3.8 1.3 9.4 0.6 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PilJ PF13675.6 EPE37142.1 - 0.97 9.5 4.2 14 5.7 0.1 3.1 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4297 PF14130.6 EPE37142.1 - 1.5 8.9 8.2 0.38 10.8 4.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4297) Helo_like_N PF17111.5 EPE37143.1 - 7.8e-05 22.1 1.2 7.8e-05 22.1 1.2 1.6 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Ank PF00023.30 EPE37143.1 - 0.00047 20.5 0.0 0.13 12.7 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EPE37143.1 - 0.0049 17.2 0.0 0.015 15.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPE37143.1 - 0.036 14.7 0.0 0.48 11.0 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) SecA_SW PF07516.13 EPE37143.1 - 0.1 12.6 0.2 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 SecA Wing and Scaffold domain Syntaxin_2 PF14523.6 EPE37143.1 - 0.13 12.6 8.0 0.031 14.6 3.4 2.1 2 0 0 2 2 2 0 Syntaxin-like protein DBINO PF13892.6 EPE37144.1 - 0.0026 18.1 16.2 0.003 17.9 16.2 1.0 1 0 0 1 1 1 1 DNA-binding domain UPF0172 PF03665.13 EPE37144.1 - 0.037 14.1 1.5 0.049 13.7 1.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) She9_MDM33 PF05546.11 EPE37144.1 - 0.2 11.4 10.5 0.23 11.2 10.5 1.0 1 0 0 1 1 1 0 She9 / Mdm33 family YqfQ PF14181.6 EPE37144.1 - 3.5 7.8 10.5 4.5 7.4 10.5 1.3 1 1 0 1 1 1 0 YqfQ-like protein RSN1_7TM PF02714.15 EPE37145.1 - 1.1e-81 274.1 15.2 1.1e-81 274.1 15.2 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EPE37145.1 - 3.8e-41 140.5 2.6 3.8e-41 140.5 2.6 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 EPE37145.1 - 1e-26 92.9 0.0 2.4e-25 88.5 0.0 2.4 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 EPE37145.1 - 6.7e-25 88.3 0.0 1.1e-24 87.6 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 EPE37145.1 - 0.0025 16.7 0.8 0.0078 15.1 0.8 1.8 1 0 0 1 1 1 1 Calcium-activated chloride channel EutQ PF06249.12 EPE37147.1 - 2e-09 37.4 0.0 2.6e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 EPE37147.1 - 6.9e-08 32.1 0.1 1.1e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EPE37147.1 - 0.0013 18.4 0.1 0.0018 18.0 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EPE37147.1 - 0.1 12.2 0.1 0.24 11.0 0.0 1.6 1 1 1 2 2 2 0 Cupin Fungal_trans_2 PF11951.8 EPE37148.1 - 7.4e-62 209.4 0.4 9.5e-62 209.0 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPE37148.1 - 5.3e-07 29.6 12.3 8.7e-07 29.0 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_72 PF03198.14 EPE37150.1 - 5.1e-112 374.2 0.0 6.8e-112 373.8 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 EPE37150.1 - 0.0058 15.8 0.1 0.013 14.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain BTB PF00651.31 EPE37151.1 - 0.00014 22.0 0.0 0.00032 20.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF4448 PF14610.6 EPE37152.1 - 0.00076 19.3 0.1 0.00091 19.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Plasmodium_Vir PF05795.11 EPE37152.1 - 0.015 14.7 0.2 0.017 14.6 0.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4148 PF13663.6 EPE37152.1 - 1.1 9.4 0.1 1.1 9.4 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) Shisa PF13908.6 EPE37152.1 - 1.3 9.2 10.8 2.8 8.1 1.5 2.1 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF4750 PF15938.5 EPE37152.1 - 3.2 7.5 7.2 0.24 11.1 2.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4750) RTA1 PF04479.13 EPE37153.1 - 0.023 14.3 0.1 0.027 14.1 0.1 1.3 1 0 0 1 1 1 0 RTA1 like protein PhaP_Bmeg PF09602.10 EPE37154.1 - 2.8e-05 24.1 2.1 0.00019 21.4 0.3 2.2 2 0 0 2 2 2 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) SesA PF17107.5 EPE37154.1 - 0.012 15.8 1.1 0.04 14.1 0.2 2.4 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Sec34 PF04136.15 EPE37154.1 - 0.012 15.5 3.6 1.7 8.5 0.1 2.8 2 1 1 3 3 3 0 Sec34-like family FAP206 PF12018.8 EPE37154.1 - 0.02 14.4 1.7 3.8 6.9 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function DUF4088 PF13317.6 EPE37154.1 - 0.044 13.4 0.2 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4088) FliJ PF02050.16 EPE37154.1 - 0.068 13.4 0.4 5.8 7.2 0.0 3.0 3 0 0 3 3 3 0 Flagellar FliJ protein DUF3782 PF12644.7 EPE37154.1 - 0.12 12.5 0.5 4.5 7.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) MCC-bdg_PDZ PF10506.9 EPE37154.1 - 0.13 12.3 1.5 0.38 10.8 1.5 1.8 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Med9 PF07544.13 EPE37154.1 - 0.13 12.3 0.4 5.6 7.1 0.1 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Phage_HK97_TLTM PF06120.11 EPE37154.1 - 0.22 10.7 2.8 1.5 7.9 0.1 2.5 1 1 0 3 3 3 0 Tail length tape measure protein Filament PF00038.21 EPE37154.1 - 0.35 10.4 2.3 2.1 7.8 0.1 2.6 2 1 0 3 3 3 0 Intermediate filament protein Sec8_exocyst PF04048.14 EPE37154.1 - 0.56 10.1 4.2 8.2 6.3 0.0 3.0 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain NPV_P10 PF05531.12 EPE37154.1 - 0.72 10.4 4.4 12 6.5 0.1 3.4 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Lin-8 PF03353.15 EPE37155.1 - 0.21 11.1 6.3 0.3 10.6 6.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BUD22 PF09073.10 EPE37155.1 - 4.6 6.5 13.3 7.8 5.7 13.3 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EPE37155.1 - 5.8 6.2 15.4 11 5.4 15.4 1.3 1 0 0 1 1 1 0 SDA1 DUF4690 PF15756.5 EPE37156.1 - 0.021 15.4 0.2 0.041 14.5 0.2 1.5 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Glycophorin_A PF01102.18 EPE37156.1 - 0.089 13.0 0.2 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 Glycophorin A ATP_synth_reg PF14960.6 EPE37156.1 - 0.15 11.6 0.3 2 7.9 0.1 2.3 2 0 0 2 2 2 0 ATP synthase regulation PolC_DP2 PF03833.13 EPE37157.1 - 0.02 12.8 0.1 0.02 12.8 0.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF2866 PF11065.8 EPE37157.1 - 0.13 12.3 0.4 11 6.1 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2866) Pec_lyase_C PF00544.19 EPE37158.1 - 6.5e-34 117.4 9.2 9e-34 116.9 9.2 1.2 1 0 0 1 1 1 1 Pectate lyase Ribosomal_L5_C PF00673.21 EPE37159.1 - 2.7e-13 49.9 0.0 4.1e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Glyco_hydro_43 PF04616.14 EPE37160.1 - 6.1e-52 176.7 6.4 1.6e-51 175.3 5.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 EPE37160.1 - 1.7e-24 86.5 5.8 4.1e-24 85.3 5.8 1.7 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 EPE37160.1 - 0.00032 20.8 0.5 0.00032 20.8 0.5 1.7 2 0 0 2 2 2 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 EPE37160.1 - 0.015 14.9 1.3 0.024 14.2 1.3 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain Herpes_BLLF1 PF05109.13 EPE37161.1 - 0.061 11.3 0.0 0.064 11.2 0.0 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF2510 PF10708.9 EPE37161.1 - 0.23 11.3 2.2 65 3.4 0.2 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2510) DUF924 PF06041.11 EPE37162.1 - 1.8e-55 187.9 0.0 3.4e-55 187.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) ACAS_N PF16177.5 EPE37162.1 - 0.079 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus Polysacc_deac_1 PF01522.21 EPE37164.1 - 0.0031 17.4 0.0 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase NmrA PF05368.13 EPE37165.1 - 3.1e-14 53.1 0.0 6.2e-14 52.1 0.0 1.5 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EPE37165.1 - 8.1e-05 22.6 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding PglL_A PF15864.5 EPE37165.1 - 0.21 11.3 2.4 8.3 6.2 0.1 2.4 2 0 0 2 2 2 0 Protein glycosylation ligase adh_short_C2 PF13561.6 EPE37166.1 - 2.4e-55 187.6 2.6 5.7e-55 186.4 2.6 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPE37166.1 - 2.1e-40 138.3 2.0 4.1e-40 137.3 2.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPE37166.1 - 0.0018 18.2 0.1 0.0018 18.2 0.1 1.6 2 0 0 2 2 2 1 KR domain p450 PF00067.22 EPE37167.1 - 2.6e-48 164.9 0.0 3.3e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EPE37168.1 - 1.4e-57 195.5 0.1 1.8e-57 195.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 3Beta_HSD PF01073.19 EPE37169.1 - 2e-40 138.6 0.0 2.6e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPE37169.1 - 1.7e-30 106.3 0.0 2.3e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPE37169.1 - 3.2e-18 66.2 0.2 4.7e-16 59.1 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPE37169.1 - 1.3e-15 57.3 0.0 7.2e-09 35.2 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EPE37169.1 - 1.2e-09 37.7 0.0 1.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EPE37169.1 - 8.5e-07 29.1 0.0 4.5e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPE37169.1 - 7.5e-06 25.3 0.0 4.7e-05 22.7 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EPE37169.1 - 8.2e-06 25.8 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPE37169.1 - 0.016 14.8 0.0 0.056 13.0 0.0 1.8 1 1 1 2 2 2 0 NmrA-like family adh_short PF00106.25 EPE37169.1 - 0.021 14.3 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.24 EPE37169.1 - 0.2 12.1 0.0 0.35 11.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain p450 PF00067.22 EPE37170.1 - 1.6e-24 86.5 0.0 4.9e-23 81.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF3937 PF13073.6 EPE37171.1 - 0.56 10.4 3.8 1.2 9.3 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3937) MFS_1 PF07690.16 EPE37172.1 - 1.5e-31 109.6 44.5 4.2e-31 108.1 44.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Glarea_lozoyensis_ATCC_20868-GLAREA/GCA_000409485.1_GLAREA_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Glarea_lozoyensis_ATCC_20868-GLAREA/GCA_000409485.1_GLAREA_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Glarea_lozoyensis_ATCC_20868-GLAREA/GCA_000409485.1_GLAREA_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Glarea_lozoyensis_ATCC_20868-GLAREA/GCA_000409485.1_GLAREA_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 21:17:22 2019 # [ok]